LOCUS       DARYXS010000001        70386 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.001, whole genome shotgun sequence.
ACCESSION   DARYXS010000001 DARYXS010000000
VERSION     DARYXS010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70386
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.001"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(697..783)
                     /locus_tag="TV193_000001"
     tRNA            complement(697..783)
                     /locus_tag="TV193_000001"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(747..749),aa:Ser,seq:gga)
     gene            complement(843..1478)
                     /gene="trmB"
                     /locus_tag="TV193_000002"
     CDS             complement(843..1478)
                     /gene="trmB"
                     /locus_tag="TV193_000002"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEL1512248.1"
                     /translation="MRVRKRKGAQEHLENNPHYVILEPEAAKGRWCEVFGNDHPIHIE
                     VGSGKGAFITGMALKNPEINYIGIDIQLSVLSYALDKVLASQAPNVRLLRVDGSSLTN
                     YFDAGEVDMMYLNFSDPWPKSRHEKRRLTYKSFLDTYKQILPENGEIHFKTDNRGLFE
                     YSLASFSQYGMTLKQVWLDLHASDYQGNVMTEYEARFAKKGQIIYRLEATF"
     gene            complement(1478..2269)
                     /locus_tag="TV193_000003"
     CDS             complement(1478..2269)
                     /locus_tag="TV193_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEL1512249.1"
                     /translation="MTTTEQDLVLTPLRGKSGKAYKGTYPNGESVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTREDMNSKQIVHILLRLHKSKQLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFRSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDCVRLTDRMYDVAYLLSHYIPRSRWADWLSYYGYKNNDKV
                     MQKIIWYAQFSYLTQILRCFDKRDMEHVNQEIYALRKFREMFRKK"
     gene            complement(2332..3366)
                     /locus_tag="TV193_000004"
     CDS             complement(2332..3366)
                     /locus_tag="TV193_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1512250.1"
                     /translation="MKALFRKRRQEFQHKHTKYLPYVFNDHFVLVLLFLLGFILFQYS
                     QLLKHFPANPLPIQLGLLIAVLFLLNLGSVATYLEKADQHFLLTKEAEVIAHIRSAER
                     LSFILWSSLQTVLLLPLFPLFQRLGVSLLAFVLLLGVLVLAKRLLLKRKVASFLSSKG
                     LDWEKAIAFEADRQQAILKFYALFTNVKGISTKVKERPYLNPILKLIKADSKKVWTNL
                     YLRAFLRSSDYLGLWLRLLLLSCLSLAFISNPYLAVGLALVFHYLSLFQLLSLYHHYD
                     YHYMSGLYPTKPQHKQRNLLSLLRQLSGLMLIVNLVLCRSWQNALVLIVAMGLLNLLY
                     LPYKLKKMID"
     gene            complement(3370..4095)
                     /locus_tag="TV193_000005"
     CDS             complement(3370..4095)
                     /locus_tag="TV193_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512251.1"
                     /translation="MLNIENVTGGYLNIPVLKDISFSVGNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYKGRISIDGLTLAEHEADYRKKIGFIPETPSLYEELTLAEHINTVAMAY
                     DIDVELAHKRAEPFLELFRLTDKLDWFPVHFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAIADLIKALEVEKAKGKSILMSTHVLDSAEKMCDRFVILHQGQVRAQGTLAD
                     LQAVFGDASASLNDIYLALTKEG"
     gene            4632..5075
                     /locus_tag="TV193_000006"
     CDS             4632..5075
                     /locus_tag="TV193_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512252.1"
                     /translation="MNLSRFLTFGLVSLSALSISGLVQTEAKANEWQTIFEKPQEVVI
                     TDGWQTISEKPQEVSTANEWQVSSEEAQESVPDKFSQNEDPSLWAVPDKFSQNEDPSL
                     WAVPDKFSQNEDPSLWAVPDKFSQNEDPSLWAVPDKFSQNEDPSL"
     gene            5528..5947
                     /locus_tag="TV193_000007"
     CDS             5528..5947
                     /locus_tag="TV193_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEL1512253.1"
                     /translation="MENCIFCSIISGEIPSSKVYEDEQVLAFLDISQTTAGHTLLIPK
                     KHVRNILAMDAETASQTFERLPKIARAIQKATGATAMNIINNNEELAGQTVFHAHVHL
                     VPRYSQEDGIAIQYTTHEPDFPALAALAQQISQEISQ"
     gene            5944..6240
                     /locus_tag="TV193_000008"
     CDS             5944..6240
                     /locus_tag="TV193_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEL1512254.1"
                     /translation="MTLKTMTTIGLTSVLAYQVYRKRHQIKETLVAMQTSKKAIQADV
                     DRIKANLAIIQKEARTLQAAGTELAYKWQAFNQEAQAHLTEIQQRMSKYQQETP"
     gene            complement(6410..7672)
                     /locus_tag="TV193_000009"
     CDS             complement(6410..7672)
                     /locus_tag="TV193_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1512255.1"
                     /translation="MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDF
                     ATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSL
                     ERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALNSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTD
                     ALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYE
                     NLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSSYQDTTAGTQESGA
                     ANVTPSPQADSPAEQQSSGATTGTPAAP"
     gene            complement(7673..8200)
                     /locus_tag="TV193_000010"
     CDS             complement(7673..8200)
                     /locus_tag="TV193_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1512256.1"
                     /translation="MSEQVVTIEEAKASDASALITLIKEAADETDFITGTEDVIAATV
                     EVLECFLEASQESLTDICLLLKVGDILAGLLNIAGKAYRETSYVGDCFMLVLKPYRNH
                     GLGQLLMETTLDWARETKQLCALELEVQARNTCAYHIYEKYGFKIEGVKRKDVKSRNG
                     DYQDVYLMRKYLERE"
     gene            complement(8193..8636)
                     /gene="tsaE"
                     /locus_tag="TV193_000011"
     CDS             complement(8193..8636)
                     /gene="tsaE"
                     /locus_tag="TV193_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEL1512257.1"
                     /translation="MFYSKNENELIAYGQGIGRQLKAGDVLVLTGDLGAGKTTLTKGV
                     AKGLGIDQMIKSPTYTIAREYEGRLPLYHLDVYRIGDDPDSIDLDDFIFGGGVTVIEW
                     GELLAKGTLHDYLEILITKTETGRQVDYLAHGHRSEALLEELKHV"
     gene            complement(9002..10462)
                     /locus_tag="TV193_000012"
     CDS             complement(9002..10462)
                     /locus_tag="TV193_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEL1512258.1"
                     /translation="MEKFFKLKENGTTVSTELMAGVTTFFAMSYILFVNPSILSAAGM
                     PSQAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFSLGFSWQEALAI
                     VFLCGLFNIFITVTKLRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANLITFSLSSA
                     EIVTVNGVEPAKATAETFANGVFSVNANGGVVPAISTFTDPSVLLAVFGLLLTAVLVL
                     KNVRGAILIGITVTTLAGIPIGVVDLSAVNFADNHISSAFAELGTTFLAAFGGMASLF
                     SDSSRLPLVLMTIFAFSLSDTFDTIGTFVGTGRRTGIFSEEDERALENSSGFSSKMDR
                     ALFADAIGTSIGALFGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFVLSVLLLPIVG
                     IVPAAATAPALIIVGVMMVSSFLDVDWSDFDVALPSFFAAFFMALCYSISYGVAGSFI
                     FYCLVKLVKGKTKEIHPILWGATFLFVLNFIILALL"
     gene            10721..11532
                     /locus_tag="TV193_000013"
                     /pseudo
     CDS             10721..11532
                     /locus_tag="TV193_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            11884..12876
                     /gene="manX"
                     /locus_tag="TV193_000014"
     CDS             11884..12876
                     /gene="manX"
                     /locus_tag="TV193_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEL1512259.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEEASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDELRKQLIKQAA
                     PGGVKANVVPINKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSIAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
     gene            13047..13856
                     /locus_tag="TV193_000015"
     CDS             13047..13856
                     /locus_tag="TV193_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEL1512260.1"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEAVQSVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
     gene            13872..14783
                     /locus_tag="TV193_000016"
     CDS             13872..14783
                     /locus_tag="TV193_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1512261.1"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKVQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            14917..15300
                     /locus_tag="TV193_000017"
     CDS             14917..15300
                     /locus_tag="TV193_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEL1512262.1"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKVARETIGNDKV
                     IKLPTLVQTIIAKLFHHQKKDKKSH"
     gene            complement(15621..16673)
                     /locus_tag="TV193_000018"
     CDS             complement(15621..16673)
                     /locus_tag="TV193_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEL1512263.1"
                     /translation="MTLDKNRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEGEADSY
                     FIVTWMIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTLLFALFG
                     FPVSLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVLLVFAI
                     FSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVYMGSLV
                     VTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPTTLGIY
                     LVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLMLFKKLG
                     FQNLLKWVDKKIPFAD"
     gene            17273..18550
                     /gene="serS"
                     /locus_tag="TV193_000019"
     CDS             17273..18550
                     /gene="serS"
                     /locus_tag="TV193_000019"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEL1512264.1"
                     /translation="MLDLKRIRTDFDTVAAKLKTRGVSEAILTSLKALDEQRRTLLVQ
                     TEELKAQRNIASAAIAQAKRQKEDASQQIADMQQLAANIKAIDAKLADIDQEITGIIT
                     VLPNTPHDSVPIGADEEDNVEIHRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYEELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLEVIKPR"
     gene            complement(18782..19552)
                     /locus_tag="TV193_000020"
     CDS             complement(18782..19552)
                     /locus_tag="TV193_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEL1512265.1"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYF
                     SSEIVEMIKSHLIDEITQLQAKPLEELLDQRYQRFRKY"
     gene            complement(19549..20415)
                     /locus_tag="TV193_000021"
     CDS             complement(19549..20415)
                     /locus_tag="TV193_000021"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEL1512266.1"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNVPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPDYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAISER
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAIKKHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            complement(20424..21788)
                     /gene="accC"
                     /locus_tag="TV193_000022"
     CDS             complement(20424..21788)
                     /gene="accC"
                     /locus_tag="TV193_000022"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEL1512267.1"
                     /translation="MFNKILIANRGEIAVRIIRAARELGISTVAVYSEADREALHTIL
                     ADQAICIGPSRSKESYLNMNSVLSAAVVTGAQAIHPGFGFLSENSKFVTMCEEMNIKF
                     IGPSGAVMDKMGDKINARAEMIKAGVPVIPGSDGEVYNAQEALEIARQIGYPVMLKAA
                     AGGGGKGIRKVESEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDSQ
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGTTLRQRMGEAAVRAAKAVSYENAGTIEF
                     LLDEASGDFYFMEMNTRVQVEHPVTEFVTGVDIVKEQLRIAAGLPLSVRQEDIVITGH
                     AIECRINAENPSFNFAPSPGKITDLYLPSGGVGLRIDSAVYSGYTIPPYYDSMIAKII
                     VHGDNRFDALMKMQRALFELEIEGIMTNIDFQMDLISDKQVIAGDYDTSFLMETFLPS
                     YNKD"
     gene            complement(21822..22244)
                     /gene="fabZ"
                     /locus_tag="TV193_000023"
     CDS             complement(21822..22244)
                     /gene="fabZ"
                     /locus_tag="TV193_000023"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEL1512268.1"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            complement(22241..22714)
                     /locus_tag="TV193_000024"
     CDS             complement(22241..22714)
                     /locus_tag="TV193_000024"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEL1512269.1"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRPMAAPA
                     PEPVTLHQEVAPISLTQEIVSKQESIPASSGLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            complement(22716..23948)
                     /gene="fabF"
                     /locus_tag="TV193_000025"
     CDS             complement(22716..23948)
                     /gene="fabF"
                     /locus_tag="TV193_000025"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEL1512270.1"
                     /translation="MTLNRVVVTGYGVTSPIGHTPEEFWSSLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAIEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAIRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAMSN
                     TFGFGGHNAVLAFKRWED"
     gene            complement(23964..24698)
                     /gene="fabG"
                     /locus_tag="TV193_000026"
     CDS             complement(23964..24698)
                     /gene="fabG"
                     /locus_tag="TV193_000026"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEL1512271.1"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKINLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILNQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            complement(24715..25635)
                     /gene="fabD"
                     /locus_tag="TV193_000027"
     CDS             complement(24715..25635)
                     /gene="fabD"
                     /locus_tag="TV193_000027"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEL1512272.1"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQYAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGV
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEARLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIEVMKANGITQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            complement(25648..26634)
                     /gene="fabK"
                     /locus_tag="TV193_000028"
     CDS             complement(25648..26634)
                     /gene="fabK"
                     /locus_tag="TV193_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEL1512273.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSIPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVIN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            complement(26829..27053)
                     /locus_tag="TV193_000029"
     CDS             complement(26829..27053)
                     /locus_tag="TV193_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1512274.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            complement(27111..28085)
                     /locus_tag="TV193_000030"
     CDS             complement(27111..28085)
                     /locus_tag="TV193_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEL1512275.1"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRH
                     ISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGAQGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            complement(28085..28519)
                     /locus_tag="TV193_000031"
     CDS             complement(28085..28519)
                     /locus_tag="TV193_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1512276.1"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     DRLHARFHKNMVGHVIADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            complement(28599..29390)
                     /locus_tag="TV193_000032"
     CDS             complement(28599..29390)
                     /locus_tag="TV193_000032"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEL1512277.1"
                     /translation="MTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIRLVK
                     DNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVRIAELVQDISFAIKQLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLVW
                     QSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFRGK"
     gene            complement(29710..30846)
                     /gene="dnaJ"
                     /locus_tag="TV193_000033"
     CDS             complement(29710..30846)
                     /gene="dnaJ"
                     /locus_tag="TV193_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEL1512278.1"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDVCHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            complement(31003..32832)
                     /gene="dnaK"
                     /locus_tag="TV193_000034"
     CDS             complement(31003..32832)
                     /gene="dnaK"
                     /locus_tag="TV193_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEL1512279.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQTALDELKKAQESGDLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            complement(33237..33806)
                     /gene="grpE"
                     /locus_tag="TV193_000035"
     CDS             complement(33237..33806)
                     /gene="grpE"
                     /locus_tag="TV193_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEL1512280.1"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSAELIADEAAEE
                     PSELELALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVEGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(33851..34885)
                     /gene="hrcA"
                     /locus_tag="TV193_000036"
     CDS             complement(33851..34885)
                     /gene="hrcA"
                     /locus_tag="TV193_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEL1512281.1"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSLIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDLYQLVKAFDFEAFKLE
                     DVLLRASQMLSDTTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLSLDESKPLTVQ
                     FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLATYQFLDEEQRLALSIRQSLSEEEMATVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            complement(35335..35907)
                     /locus_tag="TV193_000037"
     CDS             complement(35335..35907)
                     /locus_tag="TV193_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1512282.1"
                     /translation="MRKRLKFSYFLVFLVFIMVALIGPLLFNAKGTSASQEMSVPYTE
                     RQFIQLVAKEVKPLAKNYGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQAS
                     ISLKKQAASKHKTAYAIYRDREDSIRAYLSWLSQGTGEEKKLYQSLATEKGYKKPAKS
                     LQTYRYSDDKGYAQRLVQLIEARGLTSYDD"
     gene            complement(35904..36647)
                     /locus_tag="TV193_000038"
     CDS             complement(35904..36647)
                     /locus_tag="TV193_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEL1512283.1"
                     /translation="MKNNTIRVLLQALVVLLFLSGVYLFIKPEKQAVGPKANQTVPAP
                     KAAKQAKKTTDLPKVSTTDWQLVLVNRDHPQEEMSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASALYITAHSLSLEEYLTRLKEKK"
     gene            complement(36637..37344)
                     /locus_tag="TV193_000039"
     CDS             complement(36637..37344)
                     /locus_tag="TV193_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1512284.1"
                     /translation="MTKTRLYIVRHGKTMFNTIGRAQGWSDTPLTKAGEEGIRELGLG
                     LKAAGIPFKAAFSSDSGRTMQTMEIILRKSENEFLPYTRDKRIREWCFGSLDGAYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIAL
                     AVENAGGGNAIVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEYENGQFTIKTIGDM
                     SYRYRGREIIESIRDEE"
     gene            complement(37419..38756)
                     /locus_tag="TV193_000040"
     CDS             complement(37419..38756)
                     /locus_tag="TV193_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEL1512285.1"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCIDSDIDRAAAKI
                     YQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLSLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTQKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEIGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEIVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQIPAPIHSFKN"
     gene            complement(38771..39037)
                     /locus_tag="TV193_000041"
     CDS             complement(38771..39037)
                     /locus_tag="TV193_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEL1512286.1"
                     /translation="MKAIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            complement(39301..40416)
                     /locus_tag="TV193_000042"
     CDS             complement(39301..40416)
                     /locus_tag="TV193_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="HEL1512287.1"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQAIPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPLSG
                     LSGNNQGRPSLPGLNGENQKEPEQGERGEAGPPSTPNLEGNNRKNPLKGLDGENKPKE
                     DLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYEDGYGGKKHKGDYPKRFDESSPK
                     EYNDYSQGYNDNYGNGYLDGLADRGGKRGYGYSYNPD"
     gene            complement(40613..40852)
                     /locus_tag="TV193_000043"
     CDS             complement(40613..40852)
                     /locus_tag="TV193_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1512288.1"
                     /translation="MVWSLIVGAIIGMVAGRITEKSHSMGCFTMTAAGLIGSAVGQKL
                     FGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
     gene            complement(40903..41847)
                     /locus_tag="TV193_000044"
     CDS             complement(40903..41847)
                     /locus_tag="TV193_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEL1512289.1"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHGVGINALTSLRLI
                     ISGLVLSAMAYVRQREAVISLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAVGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVCFAIILMKEIFHPIDL
                     LGMALILIAVLVISLRDLLLTKRKKQLALNIKRPPSSD"
     gene            complement(42076..43515)
                     /gene="gatB"
                     /locus_tag="TV193_000045"
     CDS             complement(42076..43515)
                     /gene="gatB"
                     /locus_tag="TV193_000045"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEL1512290.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPADRRASYINALGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDPKQVSNWLQGEMAQFLNAEGKTIDQIALTPENLVEMIAIITDGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            complement(43515..44981)
                     /gene="gatA"
                     /locus_tag="TV193_000046"
     CDS             complement(43515..44981)
                     /gene="gatA"
                     /locus_tag="TV193_000046"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEL1512291.1"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIACEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLSVIAGSDRKDSTSAPVQIADYTIKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFELDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQVAVAFEATTDYHKQQPMIFGGDR"
     gene            complement(44981..45283)
                     /gene="gatC"
                     /locus_tag="TV193_000047"
     CDS             complement(44981..45283)
                     /gene="gatC"
                     /locus_tag="TV193_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEL1512292.1"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGVAITTTMADKKNIMRADIAEAGVDRKLLFQNVPEKENHFIKVPAILDDGGDA"
     gene            complement(45757..46314)
                     /locus_tag="TV193_000048"
     CDS             complement(45757..46314)
                     /locus_tag="TV193_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEL1512293.1"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYTRYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     STENHQWALNHCRTVLGAKLLDRLS"
     gene            complement(46931..47713)
                     /gene="codY"
                     /locus_tag="TV193_000049"
     CDS             complement(46931..47713)
                     /gene="codY"
                     /locus_tag="TV193_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEL1512294.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PIESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTVVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            complement(47885..49099)
                     /locus_tag="TV193_000050"
     CDS             complement(47885..49099)
                     /locus_tag="TV193_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1512295.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIANGEKILRLNTGNPA
                     AFGFEAPDEVIRDLILNARSSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIDDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGHAVHYLCDEEAEWYPDIAD
                     IKAKITERTKAIVIINPNNPTGALYPREVLEEIVAIAREHQLIIFADEIYDRLVMDGG
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKRHVRGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGRQSVDELLLPGGRIFEQRNFIYQAINAIPGLSAVKPKAGLYL
                     FPKIDRNMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKEPDHFRVVYLPTVEELADVQ
                     EKITHVLKQYKR"
     gene            49386..49838
                     /locus_tag="TV193_000051"
     CDS             49386..49838
                     /locus_tag="TV193_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1512296.1"
                     /translation="MSQTYERIMVAIDGSHGSELAFHKGVNVALRNGAALILTHVVDT
                     RALQSVATFDSYIYDKLEQEAKEVLGDFEKQAREAGLTEVKQVIEFGNPKTLLAHDIP
                     DKEEVDLIMVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
     gene            complement(50124..51512)
                     /locus_tag="TV193_000052"
     CDS             complement(50124..51512)
                     /locus_tag="TV193_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1512297.1"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQRAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMVSSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKERFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQERYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            51584..52549
                     /locus_tag="TV193_000053"
     CDS             51584..52549
                     /locus_tag="TV193_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEL1512298.1"
                     /translation="MKEILVLHTGGTISMQADEAGKVSPNQNNPMNQVGLSLEHIHLT
                     VVDFLNLPSPHITPHHMLKMYHYIQQRASQFDAVVITHGTDTLEETAYFLDTMVLPVE
                     LPIVITGAMRSANEIGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGVVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSI
                     LSLLTPDRIQGLVIEALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYR
                     GGGASLKRAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            complement(52669..54684)
                     /gene="recG"
                     /locus_tag="TV193_000054"
     CDS             complement(52669..54684)
                     /gene="recG"
                     /locus_tag="TV193_000054"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL1512299.1"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLE
                     KIVLDQEVAIFGRWDQKKAALTGMKLLMTLEDDLQPVYHVAQGISQPTLIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKAAEKRAALSAIADGSVDMIVGTHALIQDAVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHRQLDSVL
                     AWVKTELAKGTQAYVISPLIEESETLDLKNAVALEAELKDYFKASASVALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVAAEIVAAKDWQLDPRWAPILANLRVADQFD"
     gene            complement(55048..56502)
                     /locus_tag="TV193_000055"
     CDS             complement(55048..56502)
                     /locus_tag="TV193_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512300.1"
                     /translation="MEGLGGTDLDICDDSLHGSPVIKAKQLQFSYTNRRQTACELRDC
                     QIEAGQFIVLCGQSGSGKSTFLKLLNGLIPDYFSGQLQGSLKVLSHQAGQASVEVLSR
                     QVSSVFQNPASQFFYREVKHELVFPCENQGLEPALILERLDTLAADFDIKDLLEADML
                     KLSGGQKQRVAIAAAIMQGTAIMVFDEPTANLDHASVAAVKAYLKQLKAAGKTIIVAE
                     HRLHYLLDLADHFYYFSAGRLERVLSPKDLLALPDQEREELGLRRCELTAVTKALRAK
                     TVFEHYDPEHALQIKQLEVKAGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLA
                     GIFEAKEAKISYLGVTLPAKDRLSITSLVLQDVGLQLFSETVEKELNLGHHRHQATDD
                     LVNRLGLSQLLDKHPASLSGGEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVS
                     LLKELKQQKKVVIVISHDEELLDQACDSIYQLSR"
     gene            complement(56439..57119)
                     /locus_tag="TV193_000056"
     CDS             complement(56439..57119)
                     /locus_tag="TV193_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1512301.1"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGVLLGILFWLGQ
                     GRLAIGMTLLYALLLALSVLPLHVLPAYLFRLLSFAAVAGQLLYPSVLAALIFVKTTT
                     AYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKIIRQSLKIRGIFLDSWAIVRQP
                     RRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIFV
                     TIAYMVLQ"
     gene            complement(57116..57709)
                     /locus_tag="TV193_000057"
     CDS             complement(57116..57709)
                     /locus_tag="TV193_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1512302.1"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQTFGPISLVGIIMGSFFFLTGHFFASMLPAILFGCLADGIA
                     LLGKYQSRLVNLLSYLVFAFVNSGPIILMWLLKDAYIQSLLARGKDMAYVNRIMYDFT
                     VANVSWFVGVVLLCALVGGLFGQYLLKKHFAKSGMLL"
     gene            complement(57690..59372)
                     /locus_tag="TV193_000058"
     CDS             complement(57690..59372)
                     /locus_tag="TV193_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512303.1"
                     /translation="MVKSDYSTYRLVLRLLAMMKHLLAWIALAVMFAVLGFVLTVGIP
                     TSLAYLGLEVMAGHAITFKWLYLFVAMALLRGLVRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAVIIPVYFSNVLQSLLKKQNEGRRAYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAVEDLTFAYPKHQETIYHHLSVAFEKKGIIGIQGESGSGKSTLMKIIMKWYNW
                     QAGHIFLSEVDSQTLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACDEGLDTLVRGSADFSAGEAQRLELMRALLKRADCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            complement(59365..61128)
                     /locus_tag="TV193_000059"
     CDS             complement(59365..61128)
                     /locus_tag="TV193_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEL1512304.1"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTEADVLTVASQGIDSLDTYYSYYLSLAMLTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADERYEESFVNKAEAFRKATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQD
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVTIDLASKQAINQEILYVSDQSTLLNMSIYENLAMAAQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKQAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQVELEANLYG"
     gene            complement(61174..61956)
                     /locus_tag="TV193_000060"
     CDS             complement(61174..61956)
                     /locus_tag="TV193_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512305.1"
                     /translation="MSHEQGLIRVEDLSFTYRDRPILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAISSISLKQFAQKVAVVHQDNQAVADLLVGDLV
                     AVASQAHRRFFKGSSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILALIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGAIYAQGSPQEVLDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            complement(61953..62975)
                     /locus_tag="TV193_000061"
     CDS             complement(61953..62975)
                     /locus_tag="TV193_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1512306.1"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMVLLLMLLFGLMLYAVSVGGL
                     SVSYQRIFNGLFVAYDSEVALIYDLRFPRIVIALLAGAGIATSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDVI"
     gene            complement(62977..63861)
                     /gene="isdE"
                     /locus_tag="TV193_000062"
     CDS             complement(62977..63861)
                     /gene="isdE"
                     /locus_tag="TV193_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEL1512307.1"
                     /translation="MKKVIKLIGLAVLSLVLSACVDQHPRAEKKADKERIVATSVAVV
                     DICDRLSLDLVGVCDSKLYQLPKRYDAVKRIGLPMNPDMEVIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEEFYRAFKKK
                     HKGQKKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPELILRTAHAIPDKVKDMFDKEFAENDIWKHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVK"
     gene            complement(63845..64750)
                     /locus_tag="TV193_000063"
     CDS             complement(63845..64750)
                     /locus_tag="TV193_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEL1512308.1"
                     /translation="MKIINEEHMIKRLFKKLMGGLVVLLVCLAAIGGKAYADKGELYS
                     CVIRRDYRHPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLA
                     DFSGNYQFWVQPGGTGAFQAAAYSVTKVGTDTNGTTKDIAIALPDVNTVVRGSMYVEP
                     MGREVVFYLSPSELQEGYSGDMVASFAAGEAKTDHAVTAPAKADEKKAPSKPDSKDAK
                     SAPNPSARPVGQSSSPKKQSNPSKKGQAVGLSTSLDKSKQESSQKPVNNPLPVLVYYV
                     PTALLLSGALVLFIKKKRKNNEESH"
     gene            complement(64979..68730)
                     /locus_tag="TV193_000064"
                     /pseudo
     CDS             complement(64979..68730)
                     /locus_tag="TV193_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NEAT domain-containing protein"
     gene            complement(68932..70347)
                     /locus_tag="TV193_000065"
     CDS             complement(68932..70347)
                     /locus_tag="TV193_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1512309.1"
                     /translation="MRKNKLLRMIMLMTLLVPHLETARVLAEDTGAEASQVPATANEA
                     AIAQTGESTSTAAATSATDNSSSTTETTPNSGEPGATGSSSNTASSGSASGSTGQSTP
                     TSPAASPQPAPEVATQASQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAEIMEKLDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
BASE COUNT        20355 a        16870 c        13774 g        19387 t
ORIGIN      
        1 tcataaaaac gatttcaaaa acagacttgt atttcaagtg acatttgata tacttgaaga
       61 tgggaatact gcttgagtgg aggcattgta ggtctagttc aacgtaaagc agcagctgaa
      121 atcgcaaaac taatacttaa agtggggatc aagaatgtag cccctgctgc agctgcagca
      181 tcattaattt ggagctttgg aagatgcatg tggttttaat gtcaaaaaga tatagtattt
      241 gtataacatt tcttgttatt atttcgcgat tcgtttggtt tgcccttaca ggaagaagtc
      301 ctttttatga ctttattggg actatatttt taggagtagt ggttttacta attagtcaaa
      361 aagtattgaa aaaattaaag tgataaaatt attaacccga caatagcgaa gcagaatgtg
      421 atattattga tatgttccat aagatacttt ctaatgagat tgttagtgct tctcatgata
      481 agtcttatgg gacttttttg tactcaaaaa gccctatcat ttccatactg gataaatcca
      541 ctacagaaat gatagagcct aaaatatatg ttcaccaatt ggataagtta aaagaaaaaa
      601 atgaccatca ggtcaaaagc atttttcaaa atctcaaatt tgacgggtga aaaacaggcg
      661 aagactccga aacccttgat ataccaatag gataaaagga gaggagggga ttcgaacccc
      721 cgagccccgt taaggactac acgctttcca agcgtgcgca ctcggccact atgcgacctc
      781 tccaagtaaa aggctgatca actcaacctc agtagtgtat catatttttg tcaaaatagc
      841 tactagaatg ttgcttctag gcggtaaata atctgtccct ttttagcaaa tctagcctca
      901 tactcagtca tcacatttcc ttgataatca ctagcatgta aatccagcca gacctgcttg
      961 agggtcatac cgtactgtga aaagctcgct aggctatact caaataagcc acgattatct
     1021 gttttaaaat gaatttcacc attttccggc aaaatctgct tataagtgtc taaaaaggat
     1081 ttgtaggtta gtcgacgctt ttcatgcctg cttttgggcc aaggatctga aaaattcaaa
     1141 tacatcatat caacctcacc ggcatcgaaa taattggtca ggcttgaccc atcaacccgc
     1201 aagagcctaa cattaggagc ctgagaggct aggaccttat ctaaagcata gcttagcact
     1261 gatagctgaa tgtcaatgcc aatatagttg atctctgggt ttttcaacgc catacctgtg
     1321 ataaaggctc ccttgcctga gccaacctca atatggatcg gatgatcatt accaaagacc
     1381 tcacaccagc gccccttagc agcctccggc tctaaaatga catagtgagg attgttttcc
     1441 aagtgctcct gcgcaccctt tcgttttcta actcgcatta tttctttcta aacatttctc
     1501 taaattttct aagagcgtaa atctcttgat tgacatgctc catatctctc ttatcaaagc
     1561 accttaaaat ctgagttaga taagagaatt gagcatacca aataatcttt tgcatgacct
     1621 tatcattatt tttatagcca taataggata gccagtctgc ccatcgcgac cgaggaatat
     1681 agtggcttag caaataagcc acatcataca ttcgatctgt taggcgcaca caatcccagt
     1741 ccaccaaaaa aatcatgcca ctggtggtaa tcacccagtt gctatgcttg atatcaccat
     1801 gtacaatcgt ggccacctca gagcgaaatt caggtaggct gcgctttagc tccttgacga
     1861 tagcctgtaa ataagaattc tgttgaattt gcaaaggtgc attttgctca aagtctacta
     1921 aaaggtcata aggattttca attttatagt tgagctgaag caattgatta accaactgct
     1981 tggacttgtg gaggcgcagc agaatatgga cgatttgctt actgttcata tcctctctag
     2041 tcagagtacg accattgagc cactcttgag cactcatcat atcgccattc cccatacgct
     2101 ttgcccaaag caattgtggg gcaatctgtt cctttgctaa ggcaggtagg attggtgttg
     2161 tattaagctt gataaagacg ctttcgccat ttggataggt ccctttgtag gctttgccac
     2221 tttttccgcg caagggagtc aatacaagat cctgttcggt tgttgtcacc ttatcccctc
     2281 cttttctatc ttctgtaacc agttatccct attttacttg ttttaaagga cttagtcaat
     2341 catcttcttt aacttgtacg gtaagtaaag aagatttaat aatcccatcg ccacaatcaa
     2401 cacaagagca ttttgccaag aacggcagag cacaagattg acgataagca tcaaaccact
     2461 taattgcctc aacaaagaaa gtagattcct ttgcttatgc tgtggtttag tcgggtaaag
     2521 cccactcata taatggtaat cataatgatg ataaagtgat aataactgaa aaagacttag
     2581 ataatgaaag accaaggcca agcctactgc taaataaggg ttggaaataa aggcaagtga
     2641 caagcaacta agcaacaaca gacgtaacca taaccctaga taatcagagc tgcgtaaaaa
     2701 tgctcttaaa tataggtttg tccaaacctt tttactatct gccttgataa gcttaagtat
     2761 aggattcaag taaggccttt ccttaacctt ggttgagatt cctttaacat ttgtaaacaa
     2821 agcataaaac tttaaaatgg cctgctggcg atctgcctca aaagcaatcg ctttttccca
     2881 atcaagcccc ttggagctca aaaagcttgc caccttacgc tttaacagta agcgcttagc
     2941 cagcaccaaa acaccaagca atagcacaaa ggcaagcaag gaaacaccaa gcctttgaaa
     3001 caaaggaaat aaaggtaaca gcaagaccgt ttgaaggcta gaccaaagaa taaaggacaa
     3061 gcgctctgct gacctgatat gggcaataac ctctgcctcc ttggtcagca aaaaatgctg
     3121 atcagccttt tcaagatagg tagcaactga ccccagatta agcaaaaaca agacagcaat
     3181 caacaaacct agctgaatcg gtagaggatt agcaggaaaa tgcttgagta gttgactgta
     3241 ctgaaaaaga ataaagccca aaagaaacag caagacaaga acaaaatgat cattaaagac
     3301 ataaggcaga tacttggtat gcttgtgctg aaactcctga cgacgcttac gaaataatgc
     3361 cttcatagct tacccctctt ttgtcagcgc taggtaaatg tcattaagac tagctgaagc
     3421 atctccaaag actgcctgca aatccgccag agtcccttgt gcacgcacct gtccctgatg
     3481 caatatcaca aaacggtcac acattttttc tgccgaatcc agcacatggg tactcattag
     3541 aattgacttg ccctttgcct tttcaacctc taaagcctta atcaaatcag caattgctaa
     3601 ggggtcaagc cccaaaaagg gctcatcaag aataaaaaga ctagggtcaa tgacaaaagc
     3661 gcaaataatc ataacctttt gcttcattcc cttagaaaaa tgcaccggaa accaatccag
     3721 cttatccgtc aaacgaaaca gctctaagaa gggctcagct cgcttatgtg ccagctccac
     3781 atcaatatca taggccatag ctaccgtatt gatatgctct gctaaggtca gctcctcata
     3841 caggcttggt gtttctggga taaagccaat tttcttgcga taatcagctt catgctccgc
     3901 caaggttaag ccatcaatgg aaatccttcc cttatatggc tttaaaaacc caataatttc
     3961 attaatcgtt gttgacttac cagcaccatt tagaccaata agccctacta gctctccatt
     4021 tccgacagaa aagctaatat ccttcaaaac tggaatatta aggtagcctc cagtgacatt
     4081 ctcaatgttt aacatatcat ttctttctaa tatctaatct attgtagctt tgcatactag
     4141 cttccctaga tgacaggtta ttagcctaga cagataggac ttactaggca atgctttgtc
     4201 atcatcagcc tatccagcgc tttgaagcac tgataagacc aattagcttg accctactta
     4261 agaaagctgg ggcagctaat actaagggta cacttatatt agctattata acaaatttct
     4321 gcacagagcg ttaactgttt tgatcaatgc tcccatcagc taaaaacgct gagtgaatct
     4381 gaagtctatt ttaagatcat caagaaaaag gcctagctat aaaaacagag gctatattag
     4441 cttgatctat cagtcctaac catctatcac atcatattcg aatgacctgg tgatcctaaa
     4501 tagcagctca tctaaggcgt catctaaaaa atcatgataa tattatctta ttgtattgaa
     4561 tttttaataa tataatgtta tcgttaacat gtaaataagt gttgcgtctt taatgacaaa
     4621 ggaggtatgt tatgaatttg tcacgctttt taacatttgg tttggtatca ctttcagcac
     4681 tttcaatttc aggcctagtc caaacagagg ctaaggctaa cgaatggcag actatctttg
     4741 aaaagccaca ggaggtggtt atcacagatg gctggcaaac tatctctgaa aagcctcagg
     4801 aagtaagcac ggctaacgaa tggcaggtca gctctgaaga agctcaagag tctgttcctg
     4861 ataaattctc acaaaacgaa gaccctagcc tatgggctgt tcctgataaa ttctcacaaa
     4921 acgaggaccc tagcctatgg gccgttcctg ataaattctc acaaaacgag gaccctagcc
     4981 tatgggccgt tcctgataaa ttctcacaaa atgaggaccc tagcctatgg gctgttcctg
     5041 ataaattctc gcaaaacgag gaccctagcc tgtagtaaag ccatccgcac tcgattgaag
     5101 ataaggccta tgttgctgac gcttcaatct ttttttgttc taaaagcttt ctcagcctta
     5161 actgtcaaga agttccagca cctcatactc tctgaaactc ttgtccttac aaatattgtg
     5221 ccatgtcact accgtacgat agtgcgcaaa tgcacacctt tgacggacct agcttgcagc
     5281 aagtagcagg cttagttatg tgcttaacca taattgctta gtccattatc atgattcaaa
     5341 aggctttgct agtcatgtgg tcgataacca ttagcaccag ctataaacaa ttgcaatata
     5401 gaccagtaca tgctaagata actatagtat gagatagcta tggtcactga gcaactactg
     5461 atttcttatt ctaaaattat tcaactactg atttgagcca ttgctacgca gacgaaagga
     5521 ttatcacatg gaaaattgta tcttttgcag cattattagc ggtgagattc cctcctccaa
     5581 ggtttatgag gatgagcagg tactcgcttt tttggatatt tcgcaaacaa cagcgggtca
     5641 taccctcttg attcctaaaa agcatgtccg aaatatccta gcaatggacg ccgagacagc
     5701 tagccagacc tttgaacgat tacctaaaat cgctcgcgcc attcaaaaag caacaggtgc
     5761 tactgcaatg aacattatta ataataatga agagctagct ggtcagactg tttttcacgc
     5821 gcatgtgcac ctcgttcctc gctacagcca agaagacggg atcgctattc agtatacaac
     5881 acatgagcct gacttcccag ccctagcagc cttggcacaa caaattagtc aggagattag
     5941 ccaatgactc taaaaacaat gaccacaatt ggtctcacat ccgttttagc ctaccaagtg
     6001 tatcgtaaac gtcatcaaat caaagaaact ctagtagcca tgcaaacctc taagaaggct
     6061 atccaggccg atgttgatag gattaaggca aatctcgcca tcattcaaaa ggaggctcga
     6121 acgcttcaag cagcaggaac agaattagcc tacaaatggc aggcctttaa ccaagaagct
     6181 caggcccatc tgactgaaat ccaacaacgt atgagcaagt accagcagga aaccccataa
     6241 gcctaagcag actaccaagc ctcaaggtga caaaaaaggg ctctatcgtt tctgtagtgg
     6301 acaagtccgc tatagggatt atgggctctt tttgtatgta caaaaaagac gaagaaatca
     6361 ctcacaggat caagccttga tgagatttct tcgttttttt ggctgtaccc taaggcgctg
     6421 ctggcgtacc agtggttgca ccacttgatt gctgctctgc tggtgagtct gcttgagggc
     6481 taggagtcac attagctgct cctgactctt gtgtaccagc tgttgtgtcc tgatagctgc
     6541 tgctagagga cgtctctgag gaataggttg agtactgggt agatgagtct gtataggccg
     6601 gtaggctacc tgaattgtaa taatagctgc tatcctgagt agactgagtt tttaacgagc
     6661 cataaaggtt ttcgtaaact gtggcagtcg tttttagctg actaagcttt tcaaggccta
     6721 attcagcacg aatgcgattt tggatttcta aaagatgatc tgaggtcaca atttgatagg
     6781 agccgccatc tgacaaggtc gctccctcac cctttagctg ataggttttg atatttttaa
     6841 gggcgtctgt atagcctaaa agattaggaa tggttcgtga tgatatttca atgttggttt
     6901 gcatattacc actaacagct gacaagatct ttcggtagga gctgatactg ttaagggcaa
     6961 gaatcttttt cagcaccttt tgaataacct cgcgctgacg cttctgccga ccgtagtctc
     7021 cctctggatc atcatagcgc attcgagcat agaccaaggc ctgctctcca tttatcttgt
     7081 gagttcctgg tgcaacggta gcctgatact caggctcatt atctgcaata gagataggaa
     7141 agtcaaattc attggtaaca gtaatgccac caacagcatt aaccaaatca atgagccctt
     7201 gcatgttaat ctgaacgtat ttgtcaatcg tgatattcag caagtcctga acggtcatga
     7261 tagccatttg ggcaccacca gctgcataag cagcattcag cttagcttct gctccattca
     7321 tctcattatc atttggacct gacaaagtga tgagaatgtc tctttctaag cttgtcatgg
     7381 ttgtcttttt ggtcttaggg ttaatcgtaa ccagaatcat agaatcacta tttccttgcc
     7441 aggtagaggt tctgtgagac gatcctgtgt caactcccat caatagaatt gaaaagggct
     7501 ctgtctgttg aatggcatca ctttttttgg aggacgttgc aaaatcctta aaggtctttg
     7561 acaattctcc agttgaaaag gtataggcat tggttaggta aactcccata gcccccaagg
     7621 tcaacagcac aatagctgtc agcattaaaa agattttttt tccaattttc atctattcac
     7681 gttccagata tttacgcata aggtaaacat cctgatagtc tccatttctt gatttgacgt
     7741 cctttctttt gacgccctct attttaaagc catatttctc ataaatatga taggcacaag
     7801 tatttcgagc ctgaacctcc agctccaaag cacaaagctg ctttgtttct ctggcccaat
     7861 caagggtagt ctccatcaaa agctgtccta ggccatgatt gcggtagggt ttcaagacca
     7921 gcataaagca atcgccaaca tagctagtct cacgatatgc tttgccagct atatttagca
     7981 gaccagctaa tatatctccc acctttagca aaaggcaaat atctgtcaaa gactcctgac
     8041 tagcctctag aaaacactca agcacctcta cggtagcagc tatgacgtcc tcagtccctg
     8101 tgataaaatc tgtctcatca gcagcttctt taattagagt gatcaaagct gacgcatctg
     8161 aggccttggc ctcttcgatt gtcaccacct gctcagacat gcttaagctc ctcaagaagt
     8221 gcctctgatc gatgaccatg tgctagataa tcaacctgcc ggcctgtttc tgtttttgtt
     8281 attaaaattt caaggtagtc atgcagggtt cccttggcta aaagctcgcc ccactcaatc
     8341 acagtaaccc caccaccaaa gataaaatca tctaaatcaa tagagtccgg atcatcacca
     8401 atccgataaa catctaaatg atacaagggt agtcttccct catattctcg agcgatagta
     8461 taggttgggc ttttaatcat ctgatcaatc cccaaaccct tagcaacccc cttggtcagc
     8521 gttgttttac cagcacctaa gtcaccagtc aagacaagca catctcctgc ctttagctgt
     8581 ctaccaatgc cttgcccgta agcgattaat tcattctcat ttttgctata aaacataagg
     8641 ctattataac agaaaaaaaa cggtcttcca agcctaagcc agcctgtcag caaaatattc
     8701 taggctcgtc agtcctcata taatgtcgtc aaagctcaat cagctttaac atctcataaa
     8761 tcaaaagagc cagcagcaaa tcacatggac ctaacatcat ggcattctgc tgtgatagcc
     8821 agggctgaat gctctagaaa tcaacccgca gctctaaaac cttaagactt agcctaaata
     8881 taggactagg aaaaggtggc aatgcctatg agcttagaaa gtccatagtc ccagtccaaa
     8941 cggtaatccc tgtctttatt gtcccagcaa aaaagaggca cctaagtacc tcattagtcg
     9001 tttacaataa cgctaaaatg ataaaattca aaacaaataa gaaggttgct ccccaaagaa
     9061 tcgggtgaat ctccttggtt ttgcccttca caagcttcac caagcaatag aaaataaagg
     9121 agccagccac accgtatgaa atagagtagc aaagtgccat aaagaaagca gcaaagaagg
     9181 acggtagggc aacgtcaaag tcgctccaat caacatcaag gaaggacgat accatcataa
     9241 ccccgacaat gattaaggct ggtgcagtcg cagcggctgg aacaattccc acgatcggca
     9301 gcagtaaaac agataagaca aagcagacag cagttgatac agctgttaga cctgtacgtc
     9361 ctccctctgc aataccagca gcagactcaa cgtaggttgt ggtatttgag gtgccaaata
     9421 aagctccgat tgaagtacca atagcgtcag caaagagcgc acggtccatt tttgagctaa
     9481 agccagagct gttttccaaa gctctctcat cctcctcaga gaaaatccct gttcgacgac
     9541 cagtcccaac aaaagttcca atcgtatcaa aggtatcaga tagactaaag gcaaagatcg
     9601 tcattaaaac aagcggcaag cgacttgaat cactaaacag tgacgccatg ccaccaaagg
     9661 cagccaagaa tgttgtccct aattcagcaa aggctgagct gatgtgattg tctgcaaaat
     9721 taacagcaga aagatcaacc actccaatag gaataccggc taaagttgta actgtaatac
     9781 caattaggat ggctccacga acgttcttaa gcacaagcac tgctgttagc agcagaccaa
     9841 aaactgctag caaaacactc ggatcggtga aggttgaaat agctggaacc acaccaccat
     9901 tagcattaac agagaagacg ccattagcaa atgtttcagc agttgcctta gctggctcaa
     9961 caccatttac agtaacaatc tcagcagatg atagcgaaaa ggtgatcagg ttagcatttt
    10021 taaaacctag ataagcaaca aagactccaa tacctccgcc aatagcatgc tgcaggctta
    10081 ctggaatagc cttgataatg ctcttgcgaa gctttgtgac agtgataaag atattaaaca
    10141 gaccacaaag aaagacaata gccaaggcct cctgccaaga aaatcctaag ctaaaaacaa
    10201 cagtgtaagt aaagaaagca ttaagtccca taccaggagc caatgcgtaa ggcacattag
    10261 caaacaaacc catgatcaag gtagagatag cagctgcgat gatggtcgct aaaaacaccg
    10321 cttgcgacgg catacccgct gcactcaaaa tacttgggtt aacaaataag atatatgaca
    10381 tcgcaaaaaa agtcgtcaca ccagccatca gctctgttga aaccgtcgtg ccattttctt
    10441 ttaacttaaa aaacttttcc atttgaatgg agtctcctta ttgataggca aaatcaaaaa
    10501 agcccttatc tcatcagata agctttttct cttaaaacca aatgattatt atcgttttta
    10561 cgaacgatat attcatcgta acattttatc gttctatttt caatagcttt tttcgtttat
    10621 ttgccatgat cgttcaaaat ttaacagcct ttttttctat taaccgtcca agcagcaatt
    10681 ttctcttcca ctgatcctaa aatttgttat aatctagtgt atgactaaaa aactaattgc
    10741 tattgattta gacgggactt tattgcatca cgacaatacc atctctacct atactcaaaa
    10801 aaccattaag gccgtccaag ctaagggaca tgaggtcatc atctcgacag gacgtcctta
    10861 tcgtatggct attgactact accttcagct agagctaaag acacctatga ttagctttaa
    10921 tggctctttg acccacctac ctgagcaaag atggaaatac gagcataatg tgactcttga
    10981 taaggcatac cttctcaaac tcctagcagt gcaggaggac ttccagatgg actttattgc
    11041 tagtgagtac cgaaaagcct tctacattac catgaatagg cctgagagca ttgaccccaa
    11101 cctttttggt ttgaggccat cacaccagat atggctttac agatcgacaa aatcacgcag
    11161 gatccaaatg ctcttctcat gcaaacgcat catgaggata agtatgccct agccaaggcc
    11221 atgcgcgcct tcttcaagga cgaaattgag gtggactctt ggggtggtcc cttaaatatc
    11281 cttgagatgt cccccaaaaa cattaataag gcctatacct taaaatacct gcttagcatt
    11341 tacaacaagg agcctaagga tttaatcgcc tttggtgatg agcataacga cacagaaatg
    11401 ctggcctttg ccggaaccgg ctatgccatg aaaaatgcca gccctgtgct gctgcccttt
    11461 gccgaccagc agctagctta ctctaacgaa gaggacgggg tcgccagaaa actagaagag
    11521 cttttcttgt gaaagcaaac gaaaccattg tttttcagaa aacgatggtt ttcttaatgc
    11581 cgtttccgtc aattgatgaa agaatttcta atattttcgt tatttttcag catattttct
    11641 tttttatgcg gcataaaaat ccctttatta tcaatattct acttattcgg cagcgcatta
    11701 tgaaaatttt ttcatatttc gtaagatttt tccgaaaggg cttgattttt aagtgaaaac
    11761 gttttaaaat agagacgttc ttgaatttcg ttcaagtgaa aaagaattgc caaatgctat
    11821 ttggaaggag attattcttc ttcatttcaa cgaaaaatat tttaataagg aggaagaaca
    11881 agaatgggta tcggtattat tattgccagc catggtaaat ttgctgaagg tattcatcaa
    11941 tctggttcta tgatttttgg tgaacaagag aaagttcaag ttgtgacttt catgccaaat
    12001 gaaggaccag atgacttgta tggacacttc aacaatgcta tcgcacaatt tgatgctgat
    12061 gatgaaatcc ttgtactagc tgacctttgg agtggttctc catttaatca ggctagtcgt
    12121 gtggcaggag aaaatcctga tcgcaaaatg gctatcatca ctggtctaaa tttgccaatg
    12181 cttattcaag cctatactga gcgtttgatg gacgccaatg caggtgttga acaagtagcc
    12241 gcaaacatca ttaaagaatc taaggacggt attaaagccc ttcctgaaga gctcaatcca
    12301 gttgaggagg cttctacagc taatggtggt ggtcaagcgc ttcaaggagc tattcctaag
    12361 ggaactgtca ttggagatgg taagctaaaa atcaaccttg ctcgtattga cactcgtctt
    12421 cttcatggtc aggtagcaac tgcatggaca ccagcttcta aggctgatcg tattattgta
    12481 gcgtcagatt ctgtggctaa ggacgagctt cgtaagcaat tgatcaagca ggcggctcct
    12541 ggtggggtta aggctaatgt tgttccgatc aataaattga ttgaggcttc taaggaccca
    12601 cgctttggca acactcacgc tcttatcctg tttgaaactg ttcaggacgc ccttcgtgcg
    12661 attgaaggcg gcgttgagat caaagagctg aacgttggat caatagcgca ttcaacaggt
    12721 aaaacaatgg ttaacaacgt attgtctatg gacaaggatg acgttgctgc ctttgaaaaa
    12781 ttacgtgatc taggtgtttc atttgacgtt cgtaaggtgc caaatgattc taagaaaaac
    12841 ctatttgagc ttatccaaaa agcaaatgtg caataagcaa tttagaaata agaggtaggc
    12901 ttgtttaacg caacaagctg tctgcctcat ctacaatgct gcgatgatat gataagcctg
    12961 atgattgctt ctagacaaat catcatcact taataacgct ttatattgtc cattgacaat
    13021 tgactcatat acgaaaggat aacaaaatgt cagatatttc attaatttct gcaatcttgg
    13081 tcgttatcgt tgccttcttt gccggtcttg aaggtatctt ggaccaattt caaatgcacc
    13141 aaccacttgt tgcgtgtacc ttaatcggac ttgtgactgg tcaccttgaa gcaggtgtta
    13201 tgcttggtgg tactcttcaa atgcttgcac ttggttgggc aaacattggt gctgctgtag
    13261 ctcctgacgc tgctcttgca tctgttgcag cggctattat catggttaag ggtggcgact
    13321 ttactcaaaa agggattacc tttgcatact caacagctat tcctcttgcg gttgcaggtc
    13381 ttttccttac tatgattgtt cgtaccattt caactgtact tgttcacgct ggggacaagg
    13441 ctgctttaga gggtaacttc tctgctatcg agcgcttcca ctttgctgca cttcttcttc
    13501 aaggcttgcg tattgctgta ccagctgcac ttcttgttgc tgtgccaact gaggccgttc
    13561 aaagtgtctt gaaggctatg ccagcttggt tgaatgaagg tatgcaaatc ggtggtgcta
    13621 tggttgttgc cgtaggttac gctcttgtta tcaacatgat ggctacacgt gaggtatggc
    13681 cattcttcgc acttggtttt gcccttgcag ctgtgaccca attaacactt atcgctatgg
    13741 gtgttatcgg tgtggctatt gcctttatct accttaacct ttcaaaacaa ggtggtaacg
    13801 gtggaggtcg agcaggctct gctgacccaa tcggcgatat cctagaagac tactagaaag
    13861 gggtaagatt aatgactgaa caaattaaat taacaaaagc tgaccgtaaa cgtgtttggt
    13921 ggcgttcaca attccttcaa gggtcttgga actatgagcg tatgcaaaac atgggttggg
    13981 cttatgcact tatcccagca cttaaaaagc tttacacaac taaagaagat cgtgctgctg
    14041 cacttgagcg tcatatggaa ttctttaaca ctcacccata tgtggctgct cctatcatcg
    14101 gggtaacgct tgcccttgaa gaagaacgtg ccaacggtac tgctattgac aacgctgcta
    14161 tccaaggggt taagatcggt atgatgggac ctcttgcagg tatcggtgat cctgtcttct
    14221 ggtttacagt gcgtcctatc cttggtgctc ttggtgcttc tcttgcacaa actggtaacc
    14281 ttgtcggtcc actccttttc ttctttggct ggaacattat ccgtatggcc ttcttgtggt
    14341 acactcaaga atttggctac aaggctggat ctgaaatcac caaagacatg tcaggtggta
    14401 tcctacaaga catcactaag ggagcttcta tccttggtat gtttatcctt gctgtccttg
    14461 tacaacgctg ggtatctatc aactttacca tcaaccttcc aggcaagcag ctttctgaag
    14521 gtgcctatgt tgtcttccct gagggagccg ttaaaggtgc tgagctaaaa agtattcttg
    14581 gacaagctat gggtggcatg agccttgata aagttcaatc acaaaccctt caagggcaat
    14641 tagactcatt gatcccagga cttgctggat tactacttac cttcctttgc atgtggttat
    14701 tgaagaaaaa agtatcacca atcgcaatca tcattgcctt gtttgcattt ggtatcatcg
    14761 cacaccttct tcacatcatg taataaaaat taaggaattg ggggcttccc agttccttaa
    14821 tttttggctg tctagagcct tagcaaaggc cagtattcag cctgctacaa gctatatttt
    14881 tatgttataa tagacaaaaa cactaaagga cttattatgg cacaatcttt aaatcaaagg
    14941 gtgatccttc agacaacagc cgtctcctat cttggaatcg gaggaaaggt tgggaaaatc
    15001 ttacttggag ataaggcttt ggaattttac aatgataaaa acgttgagga cttcattcaa
    15061 attccctgga cggccattaa ccaaatcggt gccaatgttt ctggcaaaaa ggtcagtcgt
    15121 cactttgaaa tctttaccga tcaaggcaaa tttctctttg cttcaaagga ttcaggaaaa
    15181 atcttgaagg ttgctagaga aacaattggc aatgacaagg tcatcaagct accaaccttg
    15241 gtccagacca taatagcaaa gctatttcat catcaaaaaa aggataagaa atctcattga
    15301 tgggcctgcc ttaattcaat attacggtca tagaccagca tgataatact cttagacata
    15361 gcaccatagc aatatgtcta agagtttttt tcgttgctaa caaaaaagct tgaaaaacaa
    15421 gcttacagaa tgtagacaaa ccctatcagc gatagaaaaa ttgaaaattt agaaattgac
    15481 tatcatataa tgaaaactct ggaaaatgct gatattacag tatttttcag aattcttttg
    15541 tttttttgat taaaagaaaa agcttgaaaa acaagcttaa gtgaatcctt tctacaatct
    15601 aaatctaacc ttattcctca tcaatctgca aaggggattt tcttgtccac ccatttcaac
    15661 aaattttgaa agcctagttt tttaaaaagc atcagccttg cctgttcaac cagaaaggac
    15721 aaaaaataaa tcacaatgcc gacgccaaat atcagtagtg ggtataaaag gataggagca
    15781 ttgacaaagg gctctgcaaa atcgcgaata ataaatttga ccagcaaggg gtgtaagtgc
    15841 accagataaa tacctagagt cgttggagac acgatcacaa taaagcgtag cagcagtgtt
    15901 tctgatgtca gcttcagctt agcaaaaaga ataaataagg caatagctcc caaggtcagg
    15961 ctaggtgata cataccagta ccaaatattt cccaccataa atttcatgat ataggtaact
    16021 accaaagatc ccatataaac cgcaataaga agcttatgac taaacctact tagctctatc
    16081 ctccttagat aggctccgat aatgtagaga ataatcagcc aagtcatttc aaagcccttg
    16141 cttaaggaaa attcatcgac ctgctggttc atcagagctg ggatcaacga aaaaatagca
    16201 aaaaccagca gtaccaatcg gcctagctgc ttattggata aggtattgag gccaccattg
    16261 atcataggca taaaaatcag taacccaaag taggcggtga tataccaata attgccactc
    16321 actatgggaa agagggcctg acgccaattc tctaagctaa ctggaaagcc aaatagagca
    16381 aacaaaaggg tcatcagaaa gctataaaag aagacttgta cccaaatatt aacgattttg
    16441 gaatatttat agggcgactt aatgcccaca tagccactaa tcaacgcata gcaattgacc
    16501 gccccataaa caagaacctg aatcatccag gtaacaataa aataagaatc tgcctcacct
    16561 tcgacagttg accgcaagcc gccctttccc aaaacatgtg tgatcacaat cataaacatg
    16621 gaaatgattc gcaataaatc taaaccgtaa tggcggttct tatctaatgt cattacattt
    16681 ttacgcataa tattagttta ccacaatttt taatatttaa cgatttgatt ttgtctgaca
    16741 acgagatttt ttgtgcctct gacctaagct ctacttgtca tcagcctttt gtattactga
    16801 cgctccgtga cagacacatg aaaaagtttt agcaagaaaa gaaagctttc tgtatttcaa
    16861 ggatatgtct tgttttttat agactttact ataggaaaaa cattgaaagt gtctactcta
    16921 attccaaaat aactagttcg cgcgtttgat gtagctgaca ctcatttggg agtttacttt
    16981 ttctcctttt ttgttataat aggtctagcg gataagtagt ctggctctgt ctttcagaga
    17041 gtctgtggtt gctgaaaaca gatagaggag tcatacgaaa ttctaccgtc taccaattaa
    17101 atatgaatta agtgcacaga ttgtgaagct ggatggaacc gcgcttaggc gctccagtgt
    17161 attcataggc tgtgcttttt tatctcgtca gaaataaaaa agcgatcagc tagctttgct
    17221 catgctattt tataactgac tatcttatca ccagctcaaa ggagatttat ttatgctaga
    17281 tcttaagcgt attcgtactg attttgatac tgttgctgct aagctcaaaa cacgtggtgt
    17341 gtcagaagct atcctaacct ctctaaaagc cttagatgaa cagcggcgca ccctgcttgt
    17401 tcaaacagaa gagctaaaag cccagcgtaa tatcgcctct gctgctatcg ctcaagccaa
    17461 acgccaaaag gaagacgcca gccaacagat tgctgacatg cagcagctag ctgctaacat
    17521 caaggcaatt gatgctaagc tagctgacat tgaccaagaa attaccggta tcatcactgt
    17581 tttgccaaat actccccatg attcagttcc tattggagct gatgaagagg acaatgtaga
    17641 gattcatcgc tggggaaagc cacgtcagtt tgattttgac atcaaggcgc attgggatct
    17701 tggagaagcc ttagatatcc ttgattggga gcgtggcgca aaggttaccg gtgctcgctt
    17761 cttattctat aaaaatcttg gtgcaaggct ggagcgtgcc ctttataact tcatgcttga
    17821 tgagcaccta aaagagggct atcaagaaat cattcctcct tatatggtta atcatgactc
    17881 tatgtttggc actggtcaat atccaaaatt caaggaggat acctttgagc tagatgggac
    17941 aaactttgtt cttatcccaa ctgctgaagt cccattaacc aattactatc gtggtgacat
    18001 catagatggt aaggagctgc caatctactt tactgcaatg agcccatcat ttcgctctga
    18061 ggctggctct gctggccgcg acactcgtgg cttgattcgc ttacaccaat tccataaggt
    18121 cgaaatggtt aagtttgcta agcccgaaac atcttatgaa gagctggaaa aaatgaccgc
    18181 caatgccgag catattctcc aaaagctaaa gctcccttat cgtgtcttgg ctctttgtac
    18241 tggggatatg ggcttttcgg ccgctaaaac ctatgattta gaggtttgga tccctgctca
    18301 aaacacctat cgcgaaatct caagctgctc aaataccgaa gatttccaag cacgccgcgc
    18361 acaaattcgc taccgcgatg aggcagatgg caaggttaag ctactgcaca ccctaaatgg
    18421 ctctgggctt gctgtcggac gtaccgtagc tgctatccta gaaaattacc aaaatgagga
    18481 cggctcagtg acgattccag aagtgcttcg tccttatatg ggtggactag aggtgatcaa
    18541 gccacgttaa agccaaagac tggccggata aggtgccaac aagacgatta atgggctcta
    18601 tcatttctgt agtagataag gacacagtag aaatgatagg gcttttttct atgtacaaaa
    18661 aaggctcttt atcaattgta gggggacaaa gagccgatta atgagattga tcctaacaat
    18721 aaagaagacc tctgtaactc ctagctaact gctagcctta cagaggtctt ttttgatgtc
    18781 cttaatattt tctaaagcgc tggtagcgct gatccaataa ttcctctaag ggcttggcct
    18841 gtagctgagt gatttcgtca attaagtgtg attttatcat ctcaacaatc tcactcgaaa
    18901 aataaccccg ctccggaata atccgatcaa tgacgcccat ttgatacagc tcagctgcgg
    18961 taattttcat gagctcagca gcttcagtag ccctagagcc atccttccag agaatagagg
    19021 caaagccttc tgggctaaga acagcgtaca tggtgttttc cagcatccaa acctgatcag
    19081 caacagctaa agctaaagca ccgcctgagc cgccttcgcc aataataata gcaatgatag
    19141 gaaccttgag gtcactcatt tccatcaagt ttctagcaat agcttcacct tgaccgcgct
    19201 cctcagcacc tacgcccgga taagctcctg ctgtattgat aaaggtaatc actggacgac
    19261 caaatttttc agcctgcttc attaagcgta aggccttacg atagccctca gggtgcggct
    19321 gcccaaaatt tctagccaga ttatcttgaa gattttttcc tttttgaata ccaatcactg
    19381 tgaccggttg atcagccaaa taggcaatcc caccaacaat agagccatca tcagcaaact
    19441 gacgatcccc atgcaactcc ataaactcat caaaaatcag gctggcataa tctagagctg
    19501 tcattcgacc ctggtcacgc gcttccttta atattcttgc gacgtctgtc atgatacacc
    19561 tccatgaaat gccaccaaat gagcaatccg atcacgcagg tcagtccgct tcacaatagc
    19621 gtcaacaaag ccatgctctt ttaagaactc tgccttttga aaatcatctg gtaaattttc
    19681 tctaactgtc gtctcaatga cgcgtcgacc agcaaaacca accaaggact ggggctctgc
    19741 aataatcata tcaccctcca ttgcaaagct cgctgtcaca ccacctgtgg tcggatcagt
    19801 taggatagtc aggtaaaaaa gcccagcatt tgaatgtttc tttatagctg cagaaacctt
    19861 agccatctgc atcagactca taatgccctc ttgcatacgg gctccaccag acgctgtaaa
    19921 aataacaact gggagccgct cactaatagc cagctcaaat aagcgagtga ttttctcacc
    19981 aacaacggtc cccatgcttg ccatgataaa atgcgaatcc atgatggcta gagcaagcct
    20041 ttgtcccttg accagagctg ttccagtcag gacagcctca tgcaagccag tagcctgcct
    20101 ggccttttgc agcttggctt ggtagtctgg aaatcttaat ggatccttgg tttcaatatc
    20161 tgtaaacaat tcctgaaaag agccttcatc aacggttaaa gtcaagcgct cctgagcaga
    20221 aatcctaaaa ttataggagc aggtcggaca aatctttgcc ggccccagat ccttttgata
    20281 aatcatgtgc ttacaggcag gacacttggc aaataattcg tctggcacct ctggaacatt
    20341 acgactgaca gagcttttga gagaattatt gggagtaata cggatatatt tgtctttttt
    20401 actaaataag gccatatcta ctcctaatct ttattgtagc tgggtaaaaa ggtttccatc
    20461 aaaaacgacg tatcgtaatc acccgcaatc acttgcttgt ctgaaatcaa gtccatctga
    20521 aaatcaatat tggtcataat accttcaatc tctaactcaa acagagccct ttgcatcttc
    20581 atcaaagcat caaatcggtt atctccatga acgataatct tagcaatcat actatcataa
    20641 taaggcggta tcgtataacc actgtaaaca gcagaatcaa tcctaagccc aacacctccg
    20701 cttggtaggt aaagatctgt aatcttacca gggcttggtg caaaattaaa gcttggattt
    20761 tctgcgttaa tacgacactc aatagcatgg ccagtaatca caatatcctc ttgacgaact
    20821 gataaaggaa gacctgctgc gatccgcaat tgctccttga caatgtcaac gcctgtaaca
    20881 aactctgtta cggggtgctc tacctgaaca cgcgtattca tctccataaa gtaaaaatca
    20941 ccgctggctt catctaataa gaactcaatt gtgccagcat tctcatagga caccgccttg
    21001 gcagcacgaa cagcagcttc acccatcctt tgacgcagtg ttgtgccaat cgcaatcgaa
    21061 gggctttcct ccagtacctt ttgattgtta cgctgtaagg agcaatctct ctctccaagg
    21121 tgtatcacat gcccctgtga atcacctaaa atttgcacct caatatgcct tgccggataa
    21181 ataaccttct ccaaatacat ggcaccatta ccaaaggctc ctaaagcttc ttgactagca
    21241 gcgttaaaag cagcctctaa atcagcctcg gattcaacct ttcggattcc cttgccgcca
    21301 ccgcctgcag cagcctttag cattactgga tagccaatct gccttgcaat ctcaagagcc
    21361 tcttgggcat tgtaaacctc gccgtctgag cctggaataa caggaacacc tgccttaatc
    21421 atctcagcgc gggcgttgat tttgtcgccc attttatcca tgacagctcc tgaggggcca
    21481 ataaacttga tgttcatttc ctcgcacatg gtcacaaatt ttgaattttc acttaaaaaa
    21541 ccaaaccctg ggtggatagc ctgcgcccct gtcaccacag ctgctgataa gacagaattc
    21601 atattgagat aggattcctt tgatcttgac ggtccaatac agatggcttg gtctgccaag
    21661 atcgtatgta aagcctctct atcagcctca gaataaacag caactgtgga aatgcctaat
    21721 tctcgtgctg cacgaataat ccgcactgct atttcaccac gattggcaat taagattttg
    21781 ttaaacatag gttctttttt cctccacaga cgattagtct tttactgccc aaaagcaaag
    21841 gtcaaggtcc cactagctgc taatttgcca tcaacctctg ccttggcctc aacaactgct
    21901 attgtcccac gacgcttaat aaacctagct gtcatgacta gctggtctcc cggaaccacc
    21961 tgctttttaa attttacctt gtccatacca gcgtaaaaaa caagcttgcc tttattttcc
    22021 tcttttgata gctccaagac gccagcagtt tgtgccaagg cctccatgat caaaacacct
    22081 ggcatgactg gatactgagg aaaatgaccg ttaaagaagg gctcattgat agtgacattt
    22141 ttgatggcaa caatttcatc gtctgaagcc tctaaaattc tatcaacaag cagcattggg
    22201 tagcgatgtg gcaatgcctc ttgaatctgt tttatatcca tcatttaatg cgtaccaatc
    22261 cttgtccaaa ctcaaccacg tcctcattgg ccactaaaat ctctgtcacg ataccgtcgc
    22321 aaggagcagg aatctcgttc atgaccttca tcgcctcaac aattaacaat gtctgtccct
    22381 ttttaacgct atcaccaaca gtaacaaatg gaggcttgtc aggaccggca gcaagatagg
    22441 ccacaccaac aagaggactg tcaactactt ctccttctgg ctcttgcaga cctgaagaag
    22501 cagggattga ttcctgttta gagacaatct cctgcgtcag gctaataggg gctacctcct
    22561 ggtgcaaagt aacaggctca ggagctggag ctgccatcgg acggtgctca tttttactaa
    22621 ataacagctc cccatcactt gatttgaatg aaaattcgcg taggcttgac gcatcaaact
    22681 gtgccatcaa atcctttatc tcttgaatat tcattttaat cctcccaacg cttaaaggct
    22741 aatacagcgt tatgacctcc aaagccaaag gtatttgaca tggcataacg aatatcggct
    22801 tcttttcctt ggccaaaaat aacatttgct tcaatatcat ctgacagctc ctttgtccca
    22861 gctgtcattg gaacataatt gtgacgtatt gcttctatgg ttgcaatagc ttccacagca
    22921 ccagctgccc ctagtaggtg gcctgtaaag gacttggttg atgagacagg aacctcttta
    22981 ccaagcactg caacaatagc ctgactttct cctttttcat tagcaggagt tgaggtgcca
    23041 tgagcattca cgtagtcaat agctgctgca tcaataccgg cctcctgcaa tgctagatta
    23101 atggccttac gagcaccaag tccttctggg tgtggtgagg tcatgtggta agcgtcacag
    23161 gtattgccgt agccaacaat ctcagctaaa atagtcgcac cgcgcttttg agcatgctct
    23221 aagctttcca aaacaagcat acctgatcct tcacccatga taaaaccgtt tcgatcctta
    23281 tcaaatggaa tagagctgcg gcttgggtcc tcagttgttg acaaggcagt caagctctgg
    23341 aagcccgcaa tggcaaattt tgtaatggct gcctctgatc ctccaaccat catcacgtct
    23401 tgaagaccaa acttaattgt acgaaaggca tcgccaatag catcgtttga agaggcacag
    23461 gctgtattga ttgacttaca tacgccttgg gcattcagct tcatggcaac attaccagcc
    23521 gccatatttg gcaaggcctt tggtagagtc atcggcttaa cgcgctttgg tcctttttca
    23581 tgtaaccgaa tcacctgctc ttcaatctct tgaatgcctc caataccaga cgctacaata
    23641 acaccaaagc ggtcagaatc aatcgcttca atatctaggc cagcatgttc aatcgcctct
    23701 gtcgcagcat ataaggcata caaggaatac atgtcaaagc gatttagatc ctttttgaca
    23761 aaatacttat caaatggaaa atcctgaatc tctgctgcat tcttaacagc gaagtcactc
    23821 gtatcaaatt ttgtgatagg cttaatacca atatgacctg cctttaagct tgaccaaaac
    23881 tcctctggag tatgcccaat tggggaagtc acgccataac ctgttacaac tactctgttt
    23941 aatgtcattt taatacctct attttattgc attgtcatgc cgccgtcaat ggcaagcacc
    24001 tgaccagtaa tataatcctg actagctagg aagcttgctg cctgagcaac ctcttgcccc
    24061 ttgccaatac gcttcattgg gatttgattt aagatttgct cttgcatctt ttcagaaagg
    24121 acacctgtca tatcagattc gatgaagccc ggtgcaatcg catttacccg aatgccacgc
    24181 gccgcaacct cacgagcaac tgacttggta aagccaatca agcctgcctt ggacgctgca
    24241 taatttgctt gaccgatatt tcctgttagg ccgacaacac tagacacatt gatgatagca
    24301 ccctgacgag cctttgtcat cggctttaag accgattgtg tcatgttaaa tgctcctgtc
    24361 agattgattt tgagaacacg ctcaaagtcc tcctctgaca tcttaagcat taatttatca
    24421 ttagtgatgc cagcattgtt aatcaaaatg tccacagagc caagctgctc aatagcctca
    24481 tcaaccattc gcttagcatc agccccctct gaaacatctc ctgagatcgg cacaaccttc
    24541 acaccgtaat ccttaaaggt ctccaccagc tcatcagaaa tcgctgagcg accattgaga
    24601 acgatgttgg cgcctagtcc tgcaaattga tgagccattg ctagtccaat gcctcttgtt
    24661 gaccctgtga taaaaacgtt ttttccttta atttccatag cttagcattc cctcctattt
    24721 tcccaaatac aattgtaggc ttggcatatc ttcaacactg ctgcatagca gctttttgtc
    24781 gattttttta ataaagcctg ttaaaaccct gccagggcca atctcaacaa actgggtgat
    24841 accgttagcc ttcataacct cgatactatc ataaaaacga acaggctcca tgacctgacg
    24901 cgccaataat tctgcaatcc gatccttttc catgacctta gcctctgtat ttccaaccag
    24961 tggcagatca aagtcctgaa attgaatctt gctgagctcc tctgccaacc tttgactagc
    25021 aggcgctaaa agtgctgtat ggaaaggtcc tgagacattc agcggaatta aacgcttcac
    25081 tccctttgct tttaagattt caagtgccgc attgacagcc tcagctgtcc caccaataac
    25141 aatctgtcct ggcgtattat agttagcagg tgacacaaca ccaaccgaag aagcctcttg
    25201 acaagcctcc tcaataagcc tagcctctgt attcatcaca gctaccatct taccagagcc
    25261 agcaggcgct gcctcctcca taaagcgtcc cctttttgca actagctcta gggcagtctc
    25321 aaaactcaga acacctgccg caactagagc agaatattct ccaagagaaa gccccgccac
    25381 catatcagga tgaaccccat aagaggttaa gatacgataa atggagactg aagcggttaa
    25441 gattgctggc tgcgtgtagg ctgtctggtt caaccgatcc tggtcggtat caatgagctt
    25501 gcgtaaatca tagcctaaaa gctgactagc ctgatcaaag gtgtcacgag caatggcata
    25561 ttggtcatac aaatctcttg tcatgcctag tgtctgagca ccctgaccag caaataaaaa
    25621 ggctgttttt gtcatacttc tccttattta tatcgtttcg tttttgtcat cagctgcaag
    25681 agcttgccag cgcttagctt cttgactaat cactgctgct gcaccatagt agatatcctt
    25741 taggatggct tcacagcttt cttctgctct aattaagcct gcaatctgcc ctgccatgac
    25801 agagccattg atcacatcac catcaatcac agcgttgcgc agagctcctg ctcccatttc
    25861 ttcgatgtca ctagcagcct tacgatctgc taaaaattct ttttcagcct tagcataagc
    25921 tgatgttagc ttatttttga tagagcgtac cggatgacca acaacttgag ctgaaatgac
    25981 agtatcaatg tccttagcct tcaaaatttt atccttaaag ctttggtgag cattagattc
    26041 ctttgccaca acaaatcgag ttccaacctg aacagcctca gcacccagca taaaggctgc
    26101 tgctgcacct cgaccatctg caatcccacc tgctgcaata actggaatag aaacagcatc
    26161 taccacctgc ctaaccaagg tcatcgttgt caatttaccg atatggccac cagcctccat
    26221 tccttcagca ataacagcat caacgcctaa tttttccatg cgcttagcca gggcaacgct
    26281 aggaacaact ggaatcacga taatacctgc ctcatgaagg cgctccatgt atttccctgg
    26341 atttccagcg ccagtggtca ccaccttgac accttcttcg atcaccaaat cgacaatgtc
    26401 atctgcaaag ggagatagca gcatgatatt aaccccaaag ggcttatctg tgatcgcttt
    26461 gacacgatca atatttgcct tgaccacctc tttaggagcg tttcctccac caatgatccc
    26521 aagaccacca gcattggaga cagcacctgc tagatcacca tcagccaccc aggccatacc
    26581 tccctgaaaa atgggataat caatattaag taattctgta atacgtgttt tcataataac
    26641 cttctatgca aagaaatcag gagaataatt tgataatcaa actatcataa taagaagaaa
    26701 gagcgagtta gagcctgaaa gagggtctaa tctcaccctg atggttcgat tattacatat
    26761 caattgacca actaaagcag ttcattaatc agcaggctgg ttaatcagta ttctcgcttg
    26821 tttgagcttt attttgtttt ttcttcaacg taggcaacaa ggtcaccaac tgtgtttaag
    26881 ccttcttctg tttcgatttg aatgtcaaag gcatcttcaa tttctgagat cacttggaaa
    26941 acatcaagtg agtcagcatc taaatcatca aaggtagttt ctaaggttac ttcctctgcg
    27001 tccttgccaa gctcctcaac gataatttcc tgtacttttt caaatactgc cattttatgt
    27061 ctccttaata taaatattta ttttataaat gtgctaggca catgatataa ctagatttta
    27121 acaattagac tgccccatgt caaacctcca ccgaagcccg acagtaaaat atgctggctg
    27181 ccgtctaatt taagctgtcc attttggact gattcagata gcaaaatcgg tatactagct
    27241 gcactggtat tgccatagtg catcatattt tccagaaatt tctctcttgg cataccaatt
    27301 ttcttagcca tcttatctaa aatacgccga ttggcctgat gtaaaagcag atagtctaac
    27361 tcctccttgg ccaagcctga ttgctcaata attgctgtaa tgctccttga aacatctcta
    27421 atcgcaaagt caaagatagc acgaccatcc atctgaagaa aggagttgac ctcctgtcct
    27481 tgagaaaatg gtgagcgcag actgctctga cctgatgtca ggctttgacc ttgcgcacca
    27541 tcagtatgta aggcctcagc tagaaaatgc tgctgctcgc tggcctctaa taaaacccca
    27601 ccagcaccat ctccaaataa aacagctgtg cttctatcct gccaatcaat aatcttagac
    27661 agggtctctg ctccaataac caagcctctt tgataagccc ctgatgcaat caacttatcc
    27721 gccattgcta aggcaaagac aaagccactg caggccgctg tcatatcaaa agcaaatgca
    27781 ttagtagcac cgatagcagc ctgaaccttt gctgccgtcg atggcatgct agcatctggg
    27841 ctaatcgtag caacgatgat aaaatcaagt gcagtcgcat catatcctga ccctgctaac
    27901 aattgctctg ctacccgaat ggctaaatca ctggtcatct ccacagtgga aatgtgacgc
    27961 ttctcaatcc cagtccgtga cgaaatccat tcgtggctgg tgtccatgat ttgcgacaga
    28021 tcgtcattac taataacctg cttaggcgta taatgagcta cctgactaat ttttgaaaag
    28081 accattaaac caaatcctcc aaaaactgat gtaagttccc caagccacgt aacagggctt
    28141 gcatttcgtc ctcattcata tcagcgatca catgaccgac catattttta tggaatcttg
    28201 catggagacg atccagaaga cgcccctttt tggtcagtga caggtaaaca acccgtctat
    28261 ccacgcttga tcttgttctt tcaatatagc cctttagctc tagcttgttt aagctagtgg
    28321 taaccgttcc taaggtaacc atgagctctc ttgcgatgtc acttggcgtt acctgctgat
    28381 attttccaat aatctcaatt gtgtgcatct cctttagaga aacatcatta aattgacttg
    28441 tttttaagct catttcctca ataaccaaaa ttctgttgaa aatatcaact aaatattgat
    28501 taatcttatt atattccaag taaacacctc cctagctgta aaatactttg actatcaaag
    28561 tatatcagac atcaaagtat tttgcaagca cataagagct atttcccccg aaaatttggc
    28621 cgcctcctat ctccataagc cctgacgccc tctttaaagt cctccttaaa ggccaattcc
    28681 tcttgaatag caagctcttt ttgggcataa tcctcccaac ctgcaaaaaa gctttgccat
    28741 accaaagatt tcatgccggc gtaggaattt gaagagccac gcctcaaacg ctttaacagc
    28801 tgactacagg tcttatcaag cttatctgac tcagcagctc gatagacaaa tccgtactca
    28861 agcccttttt ctgctgtgac cccctcaccg gtcatcacca gatgagtcgc tctatttaga
    28921 ccaacggcac gtgttaacaa gaaaagacca ccagcatctg gcgctaagcc gacattaaca
    28981 aaggcctgaa taaattttgt ctgggtgcta gcaatacaaa aatccaccgc taaggcaata
    29041 ttaaaggccg caccagccac cgcaccatca gcacagagga taaccggctt tggcaattgc
    29101 ttgatagcaa aggaaatatc ctgaaccagc tcagcaatcc taactagaga ctgaacatca
    29161 tctctttcaa cagcattttg catctcaacc aagtcaccac cgactgaaaa gaccttgccc
    29221 tttgccttaa tcactaaaaa gcgcagagag gggttatcct taaccaacct aatagcctcc
    29281 agaatctcct gacaggctgg aatgttaaag ccattagaca cctctggacg atttaaggtt
    29341 aaaatggcca gatcctcttc aagctcaaaa atgatatttt gaaacgtcat atcactcctc
    29401 ttttctgaca gcttatttga ttaccaaata attttatgac caaataattt gacaatcaaa
    29461 ttaattacta gactatagta cactagaatc agtcgttatg caagaaaaag attgtaaaaa
    29521 atacattaaa attgactgcg caatttaaag catgcagccc taaaaccaag ctcagaccta
    29581 gcctctatac ctctaataaa agagcctaag acaaaagtgt cctagactct gaaactttgg
    29641 catgtgctat gctcaaccat tctatacaat tgtgatcaat cgctcataga gtgtgtaaac
    29701 aagacccgct taaatatcct ctagagcgtc tttgaccttg tcaaagaaac cttttttctt
    29761 tggagcaatc ggcttttcgc cactagcctc cgcaaaagcc ttcaaggcct ccttttgagc
    29821 ctcattgagc ttggtaggcg ttacaatgtt tacagttaca tgctggtctc cttggcctcc
    29881 gcctcgaagc ttaggagccc ccttgccctt caagcgaaat accttaccag tttgtgttcc
    29941 agcgggaata gacatggcaa catcaccatg gaccgttggg atatctactg tatctcccaa
    30001 agcagcctga acaaatgaaa tattcaagct gtagtaaata gtagagccat tgcgctcaaa
    30061 ctgtttactt ggaagcacgt ttaaaataac gaacaaatca ccataaggtc caccattaaa
    30121 gcctgcttcc ccctgaccct gtaggcggat ttgttggccg gtttcaacac ctgctgggat
    30181 ttttactgaa accttatgaa ccttcttttc atgaccagtt ccatgacagg tatggcaagg
    30241 ctctttgatt tcttgaccgc tgccatgaca gacatcacag gtcacctgac gacgcatcat
    30301 gccaagtggg gtctgcgtat caacattgat aacccctgag ccatgacatt tacggcaggt
    30361 tgtaggactt gttccaggct tagctcctga gcctgcacag gtgctacagg ttgattcacg
    30421 atgatagctg acctcttttt cggtaccaaa aacagcttcc tcaaaagaaa ggtttaccct
    30481 atattgaagg tcatcgccct gacgtggagc attgggatta cgcataccac caccgccaaa
    30541 aaagcttgag aaaatatcct caaagccgcc aaagccacca ccatcgaagc cgccaaaacc
    30601 gcctgcgcca ccaccaaagc caccgtttgc tccggctgcc ccgtattgat cataggctgc
    30661 acgcttttgt gaatcgctta gggtttcata ggcttcctgt acgtccttat atttttgctc
    30721 agctcccggc tctttattga tgtctgggtg gtatttctta gacatcttac ggtaagctcg
    30781 tttaatatca tcggccgaag cgtcctttga gaccccaaga cgatcatagt attccgtatt
    30841 attcatttat tctttccttc attgacaaaa acagacggag cgaggcgccc cgcctatttg
    30901 atttttattt atttagcctt gctatgctat tttctagcaa ttaggggagg ggactatcgc
    30961 ctcagtttct agctttactg agcgacctta gctcctcaca gcttattttt cagtgaactc
    31021 accatctaca acatcatcgc cactgtttgt tgagcctgta tctgctgcac cttctgcacc
    31081 agcctgggct tgttgtgctg cggctgcttg ctcgtacatt ttaacagcaa gggcttgtgc
    31141 tttttcatta agcgcttcaa gcttagcttt catatcatca aggtcgcctg actcttgagc
    31201 cttcttaagc tcatcaagag ctgtttgagc agcatcacgc tctgtgtcaa agcctttgcc
    31261 ttcagtttct ttaatagtct tttcagttgc aaagatagcc tggtcaactt catttttaag
    31321 gtcaacctct tccttacgtt ttgcatcggc ttcagcattg gcttcagcgt ctttcatcat
    31381 gcgttcaatt tcttcttcag aaagaccatc gttagatttg atgacaatat gttgttcttt
    31441 ttgagtacct aggtcttttg ccttaacaga aacaataccg tttttgtcga tgtcaaaggt
    31501 tacttcgatt tgtgggatac cacgaggggc tgcaggaatg tctgtcaatt ggaagcgtcc
    31561 aagtgttttg ttatctgctg ccattgggcg ttcaccctga agcacgtgga tatcaacagc
    31621 tggctggttg tctgctgcag ttgagaagac ctgtgattta gaggttggaa ttgttgtgtt
    31681 gcggtcaata agctttgtaa agacgccacc cattgtttcg ataccaagtg acaatggtgt
    31741 cacgtcaaga agaacaacgt ctttaacatc accagtgatc acaccacctt ggatagcagc
    31801 acccatcgct acaacttcat cagggttcac tgatttgttt ggctctttgc cagtttcagc
    31861 cttaacagct tcaaccacag ctgggatacg agttgaacca ccaacaagga taacctcatc
    31921 gatttctgac aagctcaagc ctgcatcaga cagcgcttgg cgaacaggaa ccttcgtacg
    31981 ctctactaaa tcacgagtca ggtcatcaaa ttttgcacga gacaggctca tctctaagtg
    32041 aagcggacca gcagcgccag cagtgatgaa tggcaatgaa atttgagttt gagtgacacc
    32101 tgaaaggtct tttttagctt tttcagcagc gtccttcaag cgttgaagag ccattttatc
    32161 ttgtgatagg tcaataccgt tttctttctt gaattctgct actaagaaat caatgatttt
    32221 ttggtcaaag tcgtcaccac cgagcttgtt gtcaccagca gttgcaagca catcaaagac
    32281 accatcaccc aattcaagga tagacacgtc aaaggtacca ccaccaaggt caaagactaa
    32341 gatcttttct tctttatctg tcttgtcaag accgtaagca agagctgctg cagttggttc
    32401 gttgacgata cgttctacct caagcccagc aatcttacct gcgtccttag tagcttgacg
    32461 ttgtgcatcg ttgaagtagg caggaactgt gataacagcc tttgttacct tttcaccaag
    32521 gtagtcctct gcatagcctt taaggtattg aagaatcatt gctgagattt cttgtggtgt
    32581 gtattcttta ccattagcag caaccttttc agaggttccc atctttgatt tgattgagat
    32641 aacagtgtca gggtttgtca ctgcttgacg cttggcagcg tcaccgacaa tgatttcacc
    32701 gtttttaaat gacactactg aaggggttgt gcggttgcct tctgggttgg caatgatttt
    32761 gctttctgtt ccttcaagaa ctgctactgc tgagtttgtt gttcctaagt caataccgat
    32821 aattttagac ataatatttt ttcctctttt atatatttat gatactcctc ttatgtggca
    32881 cggacgctag cagcttccta tggaatctca tagctgaaat ttgagcctaa agtctcaaat
    32941 tttccgagtc ataaaacact agtgttttat gacttttgcc acggcgaaga gtatcggtaa
    33001 tgctcacttc gttcgctttt gctagcgcaa aaagcagcaa tcttatttct tattttcata
    33061 gtttaccgtc atttcggaca tgattcattt tattgattag ctatcatcac gggataattg
    33121 cgacgtgaga tagcaaaatc gataccattt tgctatcgag ctagtaagga gtctaggcaa
    33181 gccgccacag cggttgccgt ctaatgacga gccatttcaa tggccatcat tagtgactag
    33241 ttgtacacaa ccaccatcgc tggtcttagt aagcgctcat gaagcttata gcctttttgg
    33301 aaaacctgag cgatactatc tgctgggtgg tcatcatctg ctggtagggt ttggactgcc
    33361 atgtgcagat tgtggtcaaa ggcttccaca ggaacctctt caataccttc ttctttaagg
    33421 gcttgaacaa ggctttcttg caccatttct aggccttttt tgacatcatc tgtcagaccc
    33481 tcaacagcca aagcacgctc caagttatct aagcttggaa ggattttttt agctaaatcc
    33541 tgtgaacgat agcgctgcaa gctttggcgt tcttcattcg cacgacgctg aatattttgc
    33601 atttctgcgt gagctctgag gtatttattt tcaaaatctt ctgctcgctg gagagccaac
    33661 tctagctcag atggttcctc ggctgcttca tcagcaataa gctcagctga ttgatcagct
    33721 tcttcaactg gctctactgc ttcctcagca gcctcatcaa gaatgtcctc ttgatccttg
    33781 agctcttctt ttggtttttt agacaaggtg tctacccctt tcttacattt tcttaaatca
    33841 tattaaggcc ttagtgaacc tcataatggt tgctgtttaa gtaacggtaa taatctctta
    33901 gcttcacagc cagtagctga ccaatcacat taatcaagct aacactacga cgataatcca
    33961 tatcaactgg cccaattaag cttaagaggc caaatcctct gtatggaatt aaaaacttgt
    34021 aggtcagcaa ggtcacgttt gctagggctg gctcactgct gtcagcaacc tgaaccgttg
    34081 ccatctcttc ctctgataga ctctgtctga tagatagggc taagcgctgc tcctcatcaa
    34141 gaaactgata ggtcgcaaga ccagcatagt caagggcagc aaccttgcca gagacaaaaa
    34201 tcgtttctcg aaaaagcccg acaaagatat aatcaaacaa atccaaaaca ttgtctgtca
    34261 ccgtaaaata cttctgaaca atctgaggga tttcggttcg cagcttgtaa tgaacagtca
    34321 taacatcttt gccaagtaag cgatcagcaa caatgccctt aagcaccagc aaatcacgat
    34381 tcataaaatt cttaggaatg gcaaactgta cggtcaacgg cttggactca tctaagctca
    34441 aaactgccaa ggcatcatga ctagatagct gaacaatatc aaagcctgtc agcctttgcc
    34501 ttgcaggctc aacatctaaa atcgccgccg tatagccggt cgtatccgat agcatctggc
    34561 tggctcttag caaaacgtcc tccagcttaa aggcctcaaa atcaaaggcc ttgaccagct
    34621 gataaaggtc ctgctcatca atgctgccaa gattaagaga atgctctaca aaatatttaa
    34681 agcctgccgc acttggcatg cgcccacttg atgtgtgagc cttctccagc aatcctagtt
    34741 tttcaagctt tgccatgtca tttctaatag tggcactact agaagcaata agtgactgca
    34801 aagccttaga gccaactggt tcatgggtct gtgtaaataa atctacaata agattcaaaa
    34861 tattagattg tctctctgtg atcacaaacc aatcactccc tttctgttag cactctatac
    34921 atcggactgc taatttataa ttctattata tccttttaaa ctagcatgtc aagaaaaaaa
    34981 ctcaaaaaat tagcactctt tttttagagt gctaattttt ataaaacatt gacagtgttg
    35041 cctttgacat tatgcttgaa agaagtaata gagagccact tactacctct cagactggta
    35101 ttggcttctc ccgactcgct agctaaaagg agcgctaagc tgtaaggggg attagcttaa
    35161 ctgcctgaag ccttaaggcc taacaatcaa gcctttagta gagcaggata aatcaggctg
    35221 cgtgctcaca gctcctactc ttaaggctta caccttcaag ctgatagaaa gttgcaatac
    35281 ctactaaagc aaatacctga gcttaccggt tgtttcggtg tctttttcat ctcctcaatc
    35341 atcatagctt gtcaaacctc ttgcttcaat cagctgcaca agcctttggg catagccctt
    35401 atcatcagaa tagcgatagg tctgcagact tttagcaggt tttttatacc ctttttcggt
    35461 tgctaggctt tggtaaagct ttttctcctc gcctgtgcct tgactaagcc atgataagta
    35521 agctctgata gagtcctctc tgtcccgata gatagcatag gctgtcttgt gctttgaggc
    35581 tgcttgcttc ttgaggctaa tggaagcctg ccctggagct ggctgcagtg aaaaaaggtt
    35641 gtggtatttg gccgccaaca gggttctgcc ataattggtt tctaaaataa tctgaccaat
    35701 caaaatagaa ggacgaatgc catagttttt ggccaatggc ttgacctcct tagcaaccaa
    35761 ctggataaat tgcctctctg tatagggaac agacatctcc tgactggccg atgtgccttt
    35821 ggcattgaac agcaagggac caatcaaagc caccataatg aacactaaaa acactagaaa
    35881 ataggaaaat ttaagtcgtt ttctcatttt ttctccttca atcgtgttag gtattcttct
    35941 aggctgaggc tatgagcggt aatgtatagg gcagaggctt taccaacata gcgataatgc
    36001 cagtcctcat actcaatccc tgtgctagtc tgcttccctt ttggatagcg caaaataaaa
    36061 ccaaattgtg gagctatttt ttgaatctcc tgtgccacct taggatcact agcgtttaag
    36121 ttatctactg tgctcatatc aatggctaga ccagtctgat gttcactagt gcctgctggc
    36181 tgggcatatt tccgaaccaa ggcttcagct gcctcttggg tcaggctagg atcatttgcc
    36241 agctcttggg caatataaga ctgataaagc tcttcttgct ggacaaccga acgataacca
    36301 gcaatcaagt gctcctgagg ttcaatcgtc tgcgccgctg ctagaaaatc agccgtctcc
    36361 tgctcaatgc gcttatcaat aggaatccca ttaatctcaa ccaactcagg actcatttcc
    36421 tcttgagggt gatcgcgatt gacaaggacc agctgccagt ccgtagttga tacctttggc
    36481 agatcagtag tctttttagc ctgcttagct gcctttgggg caggtactgt ttgattagcc
    36541 ttggggccta cagcctgttt ttcaggcttg ataaagaggt aaacccctga taaaaacaac
    36601 aggacgacca aggcctgtaa aaggactctt atagtgttat tcttcatctc ttattgactc
    36661 aattatctca cgaccacgat agcggtagct catatctcca atcgttttga tggtaaactg
    36721 cccattctca tattccacaa cagtgacgct tccattgtca atgtattgct tttccctatc
    36781 tgggtcaatt agccacataa aggttccaat ggtcatgcca tgactaacca cgatagcatt
    36841 gccacctcct gcattttcaa cagcaagcgc gatagcctca aagccctcat agatacgctt
    36901 gctcaatacc tcccagggct ctgcccagtt agcagtatca acctcgacaa tactctctgc
    36961 taattctgaa taaggcacat cacgcagatt gtcacgattt tcaaaggcct ttgttctagg
    37021 taaaacacct aaaaacagct cggaatcata agccccatct agactaccaa agcaccactc
    37081 acgaatccgc ttatctctag tgtagggtaa aaactcattt tcagactttc gtagaataat
    37141 ctccattgtc tgcatggtac gacctgaatc actcgaaaaa gcagccttga atggaatacc
    37201 agcagccttc aaaccaagtc ccaattcacg aatcccttct tctcctgcct ttgtcaaggg
    37261 ggtatcactc caaccctgtg cacgaccaat ggtgttgaac atcgtcttgc catgtctgac
    37321 aatgtataat cttgtttttg tcataatgaa cctccaaagt ctctctgcta ttatagcatt
    37381 aaaagaaaac acttgcaaaa ccatgcaagt gctagccgtt aattcttaaa gctatggata
    37441 ggagctggta tctgcccacc acgagcaata aagtcagccg atgaatgcgg attaacagcc
    37501 ataaccggag ctgtccctaa aagaccacca aaagcaatca tatcaccctc cttacccttt
    37561 ggaataatac gaacagctgt tgtcttttga ttaatcaccc cgatagctgc ctcatcagca
    37621 atcatggctg caatggtttc agacggtgtc tcctctggga tcgcaatcat atccaaacca
    37681 accgagcaaa tggcagtcat ggcttctagc ttttcaagat taagcgagcc tccctgcact
    37741 gctgcaatca tgccctcgtc ctctgataca gggataaagg cacctgacaa cccacccact
    37801 cggttgcaag ccatgacacc accctttttg actgcgtcat taagtaaagc tagggcagct
    37861 gtcgtgccat gtgtgccaac tatttcaagt cccatctcct ctaagacacg tgccacagag
    37921 tcaccaactg ctggagtggg agctagcgac agatccacaa caccaaagcc cacacctagc
    37981 cgctcacttg ccatctgtcc cactagctga ccgatacgcg tgattttaaa ggccgttttt
    38041 ttgacggtct cggctagaac gtcaaagctt tcaccacgaa ccttttccaa ggctcttttg
    38101 accacaccag gtcctgaaac accaacgtta atcaccgtat ccgcctcacc gacaccatga
    38161 aaggctcctg ccataaaagg attgtcctca acagcattag caaagactac tagctttgct
    38221 gcccctatct cagaggcttt ggcggtttcc ttgatgatac gccccatgtc tgcaactgct
    38281 gtcatattaa taccagacct tgttgatcca acattgaccg aagcgcagac cttctgtgtt
    38341 tgagccaaag cctgaggaat agactcaatc aaaatcttat cacccttttg atagcctttt
    38401 tgcacaagag ctgaaaagcc accgataaag tcaactccga tatcacaggc agcctgatcc
    38461 agagcttttg caagcgacag gtagtcttct gcgtctgttg ccgccccaat aagggctatc
    38521 ggagttacag agacgcgctt attaacaatg ggaataccta gttctgctgc aatgtcatca
    38581 ccaaccgcca caagattagc tgcctttgtc gtaatctttt ggtaaatctt agcggcagct
    38641 ctatcaatat ccgaatcaat acaatccagc aaggaaattc ccatcgtaat ggtacgaata
    38701 tcaaaatgct gctcctcaat catctcaact gtttcacgaa cctgtctaat atccatagtc
    38761 atcaagctcc ttatatgtta tgcatagcat caaaaatcgc tgcgctttga atattaatcg
    38821 tcacctgcaa ttgctttcca taagcctgaa gcacctcacg cagatgagca aaatcctgct
    38881 tttcactgct tgagacaatg gccatcatgg taaaataatc atctaaaacg gtctgtgaaa
    38941 tgtcatcaat atttaaccct aatgcagcaa tttgtcctga aacacctgcg acaatccctt
    39001 gattgtcctt accaacaact gtaatgatag ctttcatggc acacctcctc aatatgtgtt
    39061 atattttatc acaaacaaaa agagaaagct atcagagaca agaggtctgg tagccccttg
    39121 caaaaataga acaatgggta ccagaaaaaa gagtttgtta tccaattgat accgtttatt
    39181 aatatttaga ctttataata taatagcagc taataaaaga taagacgttt gaagctgcca
    39241 aaaaagctgg gtctaaggaa gcccagcttt tttgtaggtt aattaaggga tagcagaaga
    39301 ttagtcggga ttgtaagaat agccgtatcc tctcttacca cctctatcag ctagaccatc
    39361 taaatagcca tttccataat tatcattata cccttgacta tagtcattat attcctttgg
    39421 actagactca tcaaaccgct taggataatc tcctttgtgc tttttgccac catatccatc
    39481 ctcatagcca actcggtaac catcacgacg accatgattg taggggtgtt cgtctttaag
    39541 ttttggtgat tcatcatttt ctccgcttaa gcctttaccg tctaaatctt cctttggctt
    39601 attctctcca tctaatcctt ttaaaggatt tttacgatta tttccttcta aattcggagt
    39661 tgatggggga ccggcttcac ctcgttcacc ttgctctggt tccttctgat tctcaccatt
    39721 caagcctgga agcgaaggac ggccttgatt attaccactc aaccctgaaa gtgggggacc
    39781 agcctcacct cgttcacctt gctccggttc cttctgattt tcaccattca agcctttttc
    39841 tggcagcttg ggactattgc cctgaggctt tggttgaggc tgcgggctag aattatcctt
    39901 acctagatct aagtgctgtg gctttccttg tggctgatgg tgatgacctg aaccagagct
    39961 gttacctcct ctcagcccca gtggctggga aggcccttga ttaggaatag cctgaggctc
    40021 tgaggcctgt ccactactat ttccttggct gttcacactg agagactgag gttgattccc
    40081 atgatgacct gagctctttg ctgtcggctg ggacgggcta gtagcctgat gctgatgatt
    40141 agtaggctga tctgaaggct taggctgcaa gttatccttt ttcggtggcc gactgaccat
    40201 tgaatctgat gagctcttgt gcgacttatc gtcatctcca atcgagctga ctggctgctc
    40261 ctttggcctc gcttgatggg atgagccacc aagacttcct aataaacctc caaagacaag
    40321 tgcagctccc agcagcaagc tggtcaccac tgcaccggca aatagccatt gttttttgga
    40381 cttccatgtg cgaaaacgtc cttctgtttt tctcatactt ttttaactct ctccatattt
    40441 tttggtaaaa ataccaagaa atagtatata tagtcaagac tttatcatat ttcttttaaa
    40501 tttttatcat ctgatatatt cgattgtttt tacaaatctg ataaccaaaa aatcctcgta
    40561 tcatactgat acaaggattt ttatatattt gaacgtcaca agtactcctg gcttattgtt
    40621 ttttgccaaa gagcgctgaa gcaacaatta tcacaatagc tgctcctaga attgaaggga
    40681 aaacagccat gcctgccagc tgaatacccc agtcgccaaa cagcttttga ccaactgcag
    40741 agcctatcaa accagcagca gtcattgtga aacagcccat cgaatggctt ttttctgtta
    40801 tcctacctgc aaccatgccg ataatagctc caacaattaa tgaccaaacc atcgcaaatc
    40861 tcctttatgt tttgtcttat tataccatac ccttgcctta tatcagtcag atgatggtgg
    40921 tcgcttgata ttaagagcaa gctgcttttt tctcttagta agcaataagt ctctcagcga
    40981 tatcacaagc actgctatta aaatcaaggc cattcctaac agatcaatag ggtgaaaaat
    41041 ctctttcatc aggataatcg caaagcagac agaggcaacc ggctcaattg aagccagcaa
    41101 ggtagccttg atcggtccaa tgattgaagc cccctttaga aaaaaggtgt aggcaaaaat
    41161 tgtcccaata ccgataatgc caaacagggc ccgtagattc ccataagtca ttgccaatgg
    41221 gtactgccat gctcttgtca ggatcggaaa aatcactcct cccatcagca tggcaagacc
    41281 aacaatcagc aagctccccc agtcggcaat cagcttagca ggcttgatga cacagtaagc
    41341 ataggtcacc gctgcaaaaa gcccccagaa aagtccaata ggattgattg ccagatggga
    41401 aagatcacca tgacaggcca tgataaccgt tcctaggatc gctaggcaaa tagcacagct
    41461 ctctcccaca gccggcaggc gtcttgattt gaacgatagg tagaccagca ccaaaatggg
    41521 ggaaaggtat tgcaggactg tggctgtacc agcattagag taacgaatag caagcagata
    41581 ggcatattga ttaagtgtga gaccaaatag actgtaaatc aacagctctc ttaaaagcct
    41641 tttgtccttg agtaagctga tgacagcctc tctttgccgc acataagcca tagctgacag
    41701 cacaagccct gaaataatga gccttagtga ggtcaaggca ttgatgccga ccccatgagc
    41761 aattaaatat tgccctgaca cccctgagag accccaggcg attccggcta gtaaaatcat
    41821 ggtactgcct tttccatttc ttgacatatt atcttcctct ttttaatcca tgccatgata
    41881 aggccactca taataccttg atagctctag cctagacttc accaagcctg cttaacagtc
    41941 attaacaaca gaccgataag ctacctctta cagcttcgga tagcgaggta ttatcacaga
    42001 attgtcctaa agagcctacc atcataaaga gcctgaaaac tctgtttcag actcaatgcc
    42061 agtcataacg actccttaat ccagcaattt ttgcaattct tgggctaaca attgctgagc
    42121 tatctgtggg ttggcttgcc cctttgtggc cttcatcaga aaaccagtaa aggccttgtc
    42181 agcattgcgc ttgcctgatt tgaaatctgc cacagcagcc tcattgtcag caaacacctg
    42241 atgaatgatt ggaatcaaga cagctgggtc tgaaatttga accaagccgg ccttttccac
    42301 ataagcacgc gctgagccgc catgctttgc caaatgaaca aaaaccttct tggcgatttt
    42361 tgatgaaatc gtgccatcag tgatgatcgc aatcatttcc acgagatttt ctggggtcaa
    42421 ggcaatctga tcaatcgtct tgccctcagc atttaagaat tgagccatct caccctgaag
    42481 ccaattagac acctgcttag gatcaccacc aagtgccaca gcctgctcaa agaaatcaga
    42541 caaagccttt gttgctgtca gctgacctgc atcataggct gacaagccaa gagcattaat
    42601 gtagctagct cgcctgtctg ccggaaatct tggaagctct gcacgcatat cctcaatcca
    42661 tgcgtcatca atctcaaaca atggcaaatc tggctctggg aaatagcggt agtctgctgc
    42721 tccctccttg acacgcatga gaatcgttcc cttacttgcc tcgtcataac gacgtgtctc
    42781 ctgacgaata acaccgccag agcgtaggat tttggcttga cgctccacct caaactcaag
    42841 ccccttacgc acattgctaa atgagttcag gtttttcaat tctgtttttg taccaaaggc
    42901 ctcttgtccg tatggtcgca aggagatatt ggcgtccaca cgcatggacc cctcttccat
    42961 cttgacatca gaaataccag tatactgaat gatttccttt agggcagtca ggtaagcata
    43021 ggcctcctct ggagagcgca tgtcagcctc tgagacgatc tcaatcaagg gcactccctg
    43081 acgattgagg tcaacatagg aataaccatc tgtaccatgc gtatttttgc cggcatcctc
    43141 ttctaggtga gcacgctcaa tacggatttt cttggttgag ccgtcctcaa gagtaatatc
    43201 aatccagcca ttgtagccaa tcggctcatc aaactgtgaa atctgatagg ccttgggatt
    43261 gtctgggtag aaataattct tacggtcaaa gtgcatgtgc tgatgaatag acatgttaag
    43321 agcaagtgct gctttgattc ccgcatcaat gactcccttg ttcatcactg gaaggacacc
    43381 tgggaaagac cagtcaatca cattagtgct ggcatttgga tcctctccaa aatgagctga
    43441 tgaaggtgag aaaatcttag aattggtatt caactccaca tggacctcaa gtccaataat
    43501 ggtttcaaaa ttcattacct gtcacctcca aaaatcatag gctgctgctt gtggtagtca
    43561 gtagtcgctt caaaggctac cgctacctga tagatgacct cttcgctata ttttggaccg
    43621 atcaattgaa gcccaacagg caagccatct gcaaagcctg ctggaataga gattgcaggc
    43681 aagcccgcta gattcaccgg aatggtcaaa agatcagcca aatacatggc aacaggatca
    43741 tgattcaacg tatcaagctc aaaggctgct gttggtgctg ttggtcctaa aatcaagtca
    43801 taatcagcaa aaaccttctc aaagtcttga atgatcagcg tccgaacctg acctgccttt
    43861 ttgaaataag catcgtaata gcctgatgat aagctaaagg taccaagcat gatacgacgc
    43921 ttaacctcat caccaaagcc ctgactacgc gtcttgacat agatgtcctc aaggctcttg
    43981 gcatcagcag cacgaaagcc atagcgaata ccatcaaagc gctgtaggtt tgatgaggcc
    44041 tcagatgaag cgatgatata atagacagcc accccatact tgctatgtgg cagactgacc
    44101 tcctcaatga tagctcctag cttctcaaaa tgcttagcag cagccaaaac cgtctcctta
    44161 atcttaggat caatgccttc gccaaggtat tccttaggta gtgcaatctt catgcccttg
    44221 atgtcttgac cgatcttaat tgtgtagtca gcgatctgta caggtgctga ggttgagtcc
    44281 ttgcggtcac tccctgcaat gaccgatagc agctgggcat tttctcttac cgttggcgca
    44341 aaaggcccta tctgatctag cgagctgcca aaggcaatca agccatagcg agaaacagcc
    44401 ccataggtcg gcttaagccc aacaacacca ttaaaggctg ctggctgacg aatagagccg
    44461 ccagtgtctg agccaagaga taagcgaacc tgacctgaag ctactgctgt tgcagagcca
    44521 cctgatgaac caccaggaac cctgctatga tcccaagcgt ttttggtttt cttgaaataa
    44581 gacgtttctg ttgagccacc catagcaaac tcgtccatat tggtcttacc aataacaatc
    44641 atatccttgt cgtaggcatt agctaccgct gtcgcatcaa aaatcggctc ataattataa
    44701 agcatcttag aagcagcagt tgtcagaatc cccttggttg agatattgtc cttgacagct
    44761 agtggtattc ctgacatcac attgtcagga tcaatcccct tagcatcaag tgcagcagcc
    44821 tgctttaaag cagcctcgca agcaatggta atgaaagaac ccacagcctc ctcacgcgcc
    44881 ttgatatcct caagggttgc ctttgttagc tcaactgcag aaatgtcctt tgcaacaaga
    44941 agctcatgta attcttctat agtatgatga ttaaaagaca ttaggcatct cctccgtcat
    45001 caagaatagc tggtaccttg atgaaatgat tttctttttc aggaacattt tgaaacagga
    45061 gcttgcgatc cactccagcc tcagcgatat cagctcgcat gatatttttc ttgtctgcca
    45121 ttgtggtggt aatggcaaca cctgtcgtat ccacttcatt tagcaattca accatgtcaa
    45181 cgatttttga taatgttgtc gcaaactcag ttgtttcact ttctgaaaag gatagctttg
    45241 atagggccgc aacgtggcga acctcttctt cagaaatttt catgaattct cctatccaag
    45301 gtaaagcaga ccatcatcag ccacaaggcc ttgctgtttc aaacgcttga taatagcctg
    45361 aataacccaa ttttacatag tcttaaccat tatatcataa ttagctttat ttaccatagc
    45421 ggactgctgg gatttcacgt caaatgcatg tggcaactga cgttttctga taacgttttt
    45481 cataagctca acctgctttt ttcaagaaca gccaggctat aactaaactg catttgagca
    45541 attgatgagg ttaaaagggc aatgtggcta gagcatagct acctgcattt tattcacgtg
    45601 tatgcgtagc tgggattagc gaaaaactta ataacaaaaa gcctcctagc caagaccaaa
    45661 agatctcact aagaagccct taagatcagc gctgagccaa gcagcagcta atactgcctt
    45721 acttgattag cctatcccag ctgatcgaac gatcgcctaa gaaagccgat caagaagctt
    45781 tgctcctagg acagtcctac agtggttcag cgcccactgg tgattttctg ttgaattgct
    45841 cgccactgct gatgtgataa tctcaagctt gtagcccaat ttataggcat caatcgctgt
    45901 atgaaggaca caaatatccg tcagcacacc tgtcaagacc agcgtcgtga cgccacgctc
    45961 acgaagacga atatccaaat cagtccccga aaaggcagaa taatgccgct tatccagcca
    46021 aaagacccgc tgatcttgct ggtatctggt atatacggtc atcaaaggac catacaggtc
    46081 ccgacccctt gtcccgataa tattatgcgg cggaaacaag gctgcctccg gatgaaagct
    46141 atctccctcc tcgtgggcat caatcgcaaa aaagatatag tagccggcct caaaggcagc
    46201 ctcaacaacg ctagccatcg cctctgaaat cacctgagca ggtgctcctg ccgtcaggct
    46261 accatcatca gctacaaagt cattcgtgta atcaatagaa atcaaggcct tcacagctta
    46321 tccctcccca aaaagcttat gctctcttag ctgcatgaca gcaagccata agaactaagc
    46381 ctgcttttaa tattcagtat gattagacac ttatagttta ccactaaaca cgacagctgt
    46441 caagacagcg gattgattta tacacgataa aggcgaaaaa cagttatttc tgaactatag
    46501 tatagattta agtagacact ttcaacgttt ttctatatga aaataagata tattcctgaa
    46561 atagctgaac attgaaatac agaaagcctt attttcttgc taaaaatctt tcatgcatct
    46621 gtcatgttca tctcatgctg aatcacagcg aaaatacaaa aaatacccct caaaagccag
    46681 ccaatgctag aacctttgag gggacgctat aataatgtgt gaagtcctcc acagctgcta
    46741 agaaactccg ataagccgtc ataaagacca agtctagccc ttaccaagca gggctctggc
    46801 taatgaatgg ctgctctata agcagcaaga ctttgatcat agctaacact ttcactacct
    46861 gctctgacta atcacagcta gcaaagctaa aggcaagcct tgggcttagc agacgatcgc
    46921 atctgagcta ttaaaattcc tttagcttgt caaagatgcc ttcgttaatc accttgagat
    46981 aagtgccttt cattcctaga gagcgactct caatgatacc tgcactctct agctttctaa
    47041 gggcattcac gatgacagat cgtgtgattc caatacgatc tgcaatcact gaagcggtca
    47101 ggcgtccttc attgccatct agctcactaa ggatagctgc aacagccttc atttcagagt
    47161 aagatagagt gttgattgcc atattaacaa ctgtctgctt acgaatggtt tcttctaggt
    47221 tttctgtttg aagatttaac agctgaatac cgaccacagt gcttgagatt tcaactaaaa
    47281 caaggtcatc atcactgaat tcattgtcgt tacgccagat gatcaaggta cctaagcgca
    47341 tgccgccacc atagataggg gcaatcgtgg ttaaaccatc aggatagata tcctttgact
    47401 caataggaaa aatcgttagt tcattttcca cagaaaggtt tgcttcagtg tcataaacac
    47461 gactagctgc cttgacataa gcatctggga actgtcttgt ttcaaaaaat tcctcgacgc
    47521 ggtctgtgtt ggtcttgtac ttcatcgcat agccaagtaa gctgccgcca ccattgatga
    47581 tacaagcatt acaatcaata atatctgcta agcgtgaagc catagtgtta taggggagtt
    47641 ctgtttccaa gctgtctaca gaacgttgca aaatagaagt aatcttacgg gttttttcta
    47701 ataaatttgg cattttttct tttcctttta attatttgcg ttacaattat atcaaaggac
    47761 cctagctttt gcaaggaatt atcagaaaat tggctattat acctacaatt cggatgaggc
    47821 cagagcctta ttttgctgaa aaacaaaaag gatctcgcga tccaattttt gtatgagaat
    47881 catattagcg cttgtattgc ttgagaacat gcgtgatctt ttcttgcacg tcagctagct
    47941 cttctactgt tggcagatag accacgcgaa aatgatcagg ctccttccag ttgaagccac
    48001 gcccatgtac cagcatgacc ttttcttgct tcaaaagctg taggacaaat tcctcgtcgt
    48061 catcaatgcg gtacatattt cgatcaattt tcggaaacaa atagaggcct gccttaggct
    48121 ttacagctga taggcctgga atggcattaa tggcctggta aatgaagtta cgttgctcaa
    48181 agatgcgacc acccggaagc aagagctcat caacagactg acgtcctcct aaggaggtct
    48241 gcaccacctg ctgcgctaag acattggagc acaagcgcat gtttgccagc atgttcaagc
    48301 cttcaatgta acctctgaca tgtcttttag ggcctgacaa gaccatccag cccactcgaa
    48361 agccggcaat acggtgtgat tttgacagcc cattcattga cacgcaaaaa acatcaggtg
    48421 caaggctggc aattgcgata tgctccccac cgtccatgac caaacgatca taaatctcat
    48481 ctgcaaaaat gataagctga tgctctctgg caattgcaac aatctcctct aagacctctc
    48541 gagggtagag agcacctgtt gggttattgg gattgataat gacgatagct tttgtgcgct
    48601 cagtgatctt ggcttttatg tcagcaatat caggatacca ttcagcctct tcatcacaca
    48661 ggtaatgcac cgcatgccca ccacctaggc tgacacaggc tgtccaaagg ggatagtcag
    48721 gcattggcac cagcacctca tcaccattat cgagcaaggc ttgaagagac atcgaaatca
    48781 gctctgagac accatttccc aaataaatat catcaatgtc aacatcagga aagcccttta
    48841 gctgacaata ttgcatgatg gccttacgag ctgaaaaaat ccccttgcta tcagaatagc
    48901 cctcgctgga gcgagcattg agaatcaaat cacgaataac ctcatctgga gcctcaaagc
    48961 caaaggctgc tgggttacct gtatttaatc gaaggatctt ttcaccatta gctatcatac
    49021 gattagcctc gtccaggact ggacctcgaa tatcgtaggc tacgtgttct aattttgatg
    49081 atttttcaat tattttcata gtctcattac ctcgtaaccc atattataaa ccaaaacaat
    49141 taaaatagaa agcacttttc tatgagctta aagaatgcca aaagctcaac caaagctcta
    49201 agcaagctaa gcagcagcta ttaataaggc tatctaagct agcttctagc tcaaggtatc
    49261 ctcacctcag ggaatagctg ggctatttgg tgaacaatag ctcagaaaat cattaaaacg
    49321 ttttcaattt ctcctcaaaa aaggtataat agctatagag ataaagttca aaggaggata
    49381 aaccgatgtc acaaacatat gaacgtatca tggtcgctat tgatggctct catggctccg
    49441 aattagcctt tcacaagggg gttaatgtcg ctttgcgtaa tggtgctgcc ttgattttga
    49501 cccatgttgt tgatacacgt gcgctgcaaa gcgttgcaac ctttgatagc tacatttatg
    49561 acaagttgga gcaggaagct aaagaggtct tgggggattt tgaaaaacaa gcacgcgagg
    49621 cagggctgac tgaggtcaag caggtgattg aatttggcaa tcccaaaacg ctattagcgc
    49681 acgatatccc tgacaaagaa gaggttgatt tgattatggt tggggcaact gggcttaaca
    49741 cctttgagcg gttgctgatt ggatcatcat ctgaatatat ccttcgtcat gccaaggttg
    49801 acctattagt ggttcgagag catgacaaaa ccctgtagca agacgaattc tctcagctgt
    49861 cagaagcatt tgcagcctaa gtgaagtaac catacctagc ccttagcctc agctcacaag
    49921 gctactaaag gactactgct ctcatatact aattaccact agctagactt aagggccctt
    49981 ttattgaggg tgtctagtct acatcaaaaa gcaccctgag ctaataagtg aagtgacccc
    50041 aagtgttagg ccaaatgctt aacagctagg agatcaactc acagctcaag gtgcttttta
    50101 atgcctctaa aataaagaca gccttatttt tccaagcgct gcaatgattt ttgaagctgc
    50161 ttgtccaact cttttttgat ggctgactct ggtgcatagc gctcctgcca gtcatctggc
    50221 ttttgaattt tatgcgttat gggatcaaaa tgcgctttcc catcagggaa aattttcccc
    50281 atattggctt catggacggt ctcaaaaatg ggctgagggt ccactcccat caatacaaat
    50341 gagccatagg taaaataaag cagatctgtc aaagcatcaa cctgcccaac caggggtgac
    50401 tctgggtgct ccttggcctg caccttctta gctgccttat caagggcagc atggaggtct
    50461 atcaaagcct gagaaaagcg atgcttatcc ccttgactgg ctgcataaag aaattccaca
    50521 agttcctcta ccttaaaatc tgctcgatag ccagcctcct ttaaggaata gcctcttggt
    50581 gtttcaatcg tgtctccgtc catcaggcgg tggaaatcct tgaccttgtt gaaattatca
    50641 tcgcgacttt taaagctttt ttccacatca aaatgaatca agccataatg cgccagcgcc
    50701 ttagagatac catcattgtt atttgaagct gttgtaaagt gagcaccgct tttaaccact
    50761 gcctcagcat ttcccatcgc aacaccaaca ccaacgcctg agagcatttc taagtcatta
    50821 tcagagtcgc caaaggccat gacctctgag agctcaaagc caaacatctc gcccaagcgt
    50881 tcaatgccct tgattttaga ctgcccgcta gaaatcaaat ctaaggaata agggctgctt
    50941 ctggttacct tgatatgcgg gaatctttcc ttgatttttt gggtgtcatc aacagaagca
    51001 accaagacaa tctgataaat cggctctctc ataatggtaa caagattgct gaagctttgc
    51061 ggcttaaagc gtctgatgag gtttttaaag ctgccctcaa ccgtcttgac cagactcctt
    51121 ggcacaatac tgctaaccat ctgaccaaat ggactggttc ccatatcaat gatccgagac
    51181 ccagcaagac ctgaagctgt tcctaaggag atctcgcgct ttttatcgct agcatagcga
    51241 atgattttat aaatggttga ctttggcagc tggttctgat acaagacctt gtctcgtgtc
    51301 aaaatgtatt gaccattgta ggtcactgca aaatccaagc caaaattttc taaaaagggc
    51361 tgcacaaaag caggtccacg accagttgcc agcccaacca taataccttg tttttttaat
    51421 tgctgaatag ccctttgcgt cgttttttga acattttttc gatcattaag cagggttcca
    51481 tcaatgtcga aaaagactgc ttttattgtc aaatccttct gttctctctt ctatttgtga
    51541 taaaataaat tatatcataa attgaaagaa gtatgagtat caaatgaagg aaatcctcgt
    51601 cttacatacc ggcggcacca tttcaatgca ggctgatgaa gcaggcaagg tgagcccaaa
    51661 tcaaaacaat ccaatgaatc aggttggcct tagcctggag catatccacc taactgttgt
    51721 ggatttttta aatctgccaa gcccgcacat cacccctcac cacatgctca agatgtatca
    51781 ttacattcaa caaagggcta gtcagtttga tgcagtggtc atcacacatg gtacagatac
    51841 cttagaagag actgcttatt ttctagacac aatggtgctg cctgtagagt tgcctattgt
    51901 tatcacaggt gctatgcgct cggccaacga gattggaagc gatggtatct ataactacct
    51961 aacagcgctt agggtagcca gccatgagaa agccaagggc aagggggtgc tggttgtgat
    52021 gaatgatgaa attcatgccg ctaagtatgt caccaaaacg cataccacca atgtttcgac
    52081 ctttcaaaca ccgactcatg gccctttggg agtcgtcatg aaggacgatt tactgttctt
    52141 taagactgct gagccaaggg ttcgctttga gcttcgtcat atttctggca cagttccgat
    52201 tatcaaggcc tatgctggta tgggagatgg aagtatttta agccttttga cacctgatag
    52261 gattcaggga ctagtgattg aggccctcgg cgctggaaat gttcctcccc tagcagtatc
    52321 tgagctcgaa aaattaatcg cctctgggat tcctgttgtc ttggtctcgc gctgcttcaa
    52381 tggcatagca gagccagttt atgcttatcg cggaggtggt gccagcttaa aaagggctgg
    52441 tgttatgttt gtcaaggagc taaatgcccc taaggccagg ttaaaattgc tcatcgccct
    52501 caacgctggg cttacaggtc aagagctgaa ggattatatc gaaggctaag ctctcctata
    52561 atcacaggct actactcctc atctatagca caaaaagcac gactcggtca gctaagaacc
    52621 tcttgtcgtg tttttatatt agctctgtcc agcaagtcag cctcacatct aatcaaactg
    52681 atcagcgaca cgaagattag ccaaaatcgg agcccatcta gggtccagct gccaatcctt
    52741 agctgcaaca atctcagcag cgactcgtct tgcctcctct aggatatgat aatcctctac
    52801 aatatcagct gttttgaact ctggcaaacc tgattgacgg gtcccaaaaa tctctcctga
    52861 gccacgcagc ttgaggtcag cctctgccag cacaaagcca tcattagtcg ttgtcatgat
    52921 ggtcatacgc tccttgcctg agtctgtctt aggatctgcc accaaaatag cataggattg
    52981 cttgctgcct cgcccaacac gaccacgcaa ctgatgcaat tggctaaggc caaagcggtc
    53041 agcattcatg atcagcatga tggtggcatt tggcacattg acaccaacct caataacggt
    53101 tgttgacacc aagacatcaa tctccttagc cttaaagcgc tgcatgatca tctccttgtc
    53161 gtctgccttc attttgccat gcatcaaggc aacactagct gaagctttaa aataatcctt
    53221 cagctcagcc tctaaagcta ccgcattttt caaatctaga gtttcagatt cttcgatcaa
    53281 aggagagata acataggcct gtgtcccctt agcaagctcg gtctttaccc aggccagcac
    53341 actatctaat tgccgatgct tgacccagcg agtgatgatt ggctttcgcc ctgccggtaa
    53401 ttcatcaata atggaaacgt ccatctcacc ataggcagtt atggctaggg ttctaggtat
    53461 gggagtagct gtcatcatca aaacatctgg attgttgcct ttttcgcgaa acaagcgacg
    53521 ctgattgacc ccaaaacggt gctgttcatc agtaatcacc agccctagct tatgataggt
    53581 cactgcgtct tggatcaagg catgcgtccc aacaatcata tccacagacc catcagcaat
    53641 agccgataaa gctgctcttt tttcagctgc tttcataccc gatgtcaaca gggcaataga
    53701 caaatctgga aagagctgac aaagactatc gtaatgctgc tcagctaaaa tctcagttgg
    53761 caccatgagt gccgattgaa atcccgctgt ttgggcagca tacatggcaa ggcttgcgat
    53821 cactgtcttg ccagagccga catccccctg caacagacgg ttcatatgag cccctgaggt
    53881 catatctgct aagatttcct ccaggcttct ttgttgagct ctggtcagtg aaaagggcaa
    53941 agcagcaatc ttttttgcca ctgcctgctg atgaaaagga atcgctaacc cattgccctc
    54001 tgccttgtta gcaagcttta aaacctgcag attcatctga aaatagaaaa attcttcaaa
    54061 ttttatacgg cgcagggcct gcttataatc ctccatatgt ttaggaaaat gcatggcata
    54121 aacagcagct tgtctcggca gcaggcggta tttctgaatc aagggctctg gtaaattttc
    54181 ttccagctga gctaaggcac cgctatcaaa ggctgatctg atcgccttaa tcagggtggg
    54241 ttgactgatc ccctgcgcca catgataaac tggctgcaaa tcatcttcta aggtcatgag
    54301 caatttcata cctgtcaagg ctgctttttt ttgatcccac ctaccaaaga tagccacttc
    54361 ctgatccaag acgattttct caagcagata aggctgattg aaaaagctga cactaatcac
    54421 aagctccccc tgcttcaatt taaagctcag gcgattacgc ttgaacccat agtattgaac
    54481 gcttggtgga gtcacaactc tacctgtaag gacagccttt tcaccatcta aaagctctaa
    54541 ggctgacttg cttttaaaat cctcatagcg aaaaggataa tagagtagca agtccttgat
    54601 ctgataaatg cctaattttt gaaatttctc agctgacttt ggaccaagac ccttcaaatt
    54661 agcaatcgaa ctctttaaca gcatctcaac ctcgctttct ttttcattat tatatcaaaa
    54721 atcaagagcc tctccaaaaa ggaagaggct cgttttctta ctgtagatgc cttgaggtat
    54781 tagccgatcc taacacaccc ttagtgcggc cgctaggacg gcctaactaa aagatgaaga
    54841 gtggcatata aacaatacag cactgcttgc taggccaaga tatgccctag aattgtgata
    54901 gctactgcta gcttgtcaag agttggcggc ttgtgattgg tcaatcgcag ctagtggtta
    54961 tcagatcaag caggaacacc tgctgctcca aggagcgata aagccatcac caatacagca
    55021 ccagaccgct tgagcaaggc taggccttta cctgctcaac tgatagatac tatcacaggc
    55081 ttgatccagt aattcctcgt catgagagat gacaatcact accttttttt gctgctttag
    55141 ctcctttaaa agactaacca gagcctgcat ttgcagcaga tctaagccac tgcttggctc
    55201 atcaagaatg acaatctcct tgtcagacaa gaggctggca gcaatcatca ccctttgctg
    55261 ctcaccacct gataggctgg cagggtgctt gtctagaagc tgagaaagcc caagcctatt
    55321 caccaaatca tcagtagcct gatgtctatg atgacctaga ttaagctcct tttctaccgt
    55381 ctccgaaaat agctgtagcc caacgtcctg caacactagg cttgtgattg aaagcctgtc
    55441 cttagcaggc agggtgacac ccagatagct gatcttggcc tcttttgctt caaaaatacc
    55501 tgccagatat aaagccaact gcgattttcc caaaccgtta gctccggtaa tgccagtgat
    55561 ttgccctgca ccaaagctga gctgattgag gtgatacaaa accctgctgc ctgccttgac
    55621 ctctagctgc ttgatttgca aggcatgctc tggatcataa tgctcaaaaa cagtttttgc
    55681 ccgcaaagcc ttagtcacag cagtcaactc acatcgtctt agtcctagct cctcacgttc
    55741 ctgatctggc aaagctagca gatccttggg gcttaatacg cgctctagcc taccagctga
    55801 aaaatagtaa aaatggtctg ccaaatccag caaataatgc aagcggtgct cagcgacaat
    55861 aatggttttg ccagcagcct taagctgctt taaataagcc ttgaccgctg ctacactagc
    55921 atggtccaaa ttggctgttg gctcatcaaa aaccatgata gctgtccctt gcatgatagc
    55981 tgctgcaata gccacccgct gcttttgacc accagatagc ttaagcatat ctgcttctag
    56041 taagtccttg atgtcaaaat cagctgccaa ggtatccagc ctctcaagga taagagctgg
    56101 ctctaagcct tgattttcac aaggaaaaac aagctcatgc ttgacctcac gatagaaaaa
    56161 ttggctggct gggttttgaa agacagagga aacctgcctt gacagcactt caacactagc
    56221 ctgaccagcc tgatgagaca gtactttcag acttccttgt aattgtcctg aaaaatagtc
    56281 tggaatcaag ccattgagca gcttaagaaa ggttgacttg cctgagcctg actgaccaca
    56341 aagcacgata aattgacctg cctctatctg acaatccctg agctcacagg cagtctgcct
    56401 acgattggta taggaaaact gcagctgctt tgccttgatc actggagaac catgtaggct
    56461 atcgtcacaa atatccaaat ctgtaccccc caatccttcc atgatagatg tgatacgaag
    56521 cactcacttg ctcccttttt gattgctagc ccttttgtta ggctagcaat ggttaagtcc
    56581 tgactacttc tcagcaatga catcaacagc ggtaccaaga gatactccat ataccgcctt
    56641 ggctgtctga caatagccca gctgtccaag aaaatgcccc tgattttcag agattgccga
    56701 ataatctttc cttcttgcct gatcttaggt aaaaaacgca gcatgacagc aagagtcaac
    56761 agacaaacct ctggcacatg ccattttcgc agcccatgca caagctcgta ggcagtcgtt
    56821 gtcttgacaa aaatcaaagc agcaagcaca gatgggtaaa gcaattgacc agcaacagct
    56881 gcaaagctca gcagcctaaa cagataggct ggcagcacat gaagcggcaa tacagacaaa
    56941 gcaagcagta aggcatagag cagtgtcata ccgattgcca gacgcccttg accaagccaa
    57001 aacaaaatgc caagcaaaac acctataatc atcgtcccca gccagccatc aatccgaaaa
    57061 aagaagcagg cattggctag aattaacagg agcaattttg tgcgaacatc aagcctcata
    57121 aaagcattcc tgacttagca aaatgctttt tcagcaggta ttgaccaaaa aggccaccta
    57181 ctaaggcaca aagaaggaca acaccaacaa accagctaac atttgcaacg gtaaagtcat
    57241 acatgatacg gttaacatat gccatgtcct taccacgcgc taaaagactc tggatatagg
    57301 cgtccttcaa cagccacatt aaaataatag gaccactgtt aacaaaggca aaaacaagat
    57361 aagacaagag attcactagt ctagattgat attttcctaa aagggctatg ccatctgcca
    57421 aacagccaaa aagaatagct ggtagcattg aagcaaaaaa atgacctgtc aaaaagaaaa
    57481 agcttcccat aataattcct actaggctta tcggtccaaa ggtctgcagc ttagcgatta
    57541 atagcatata aactggcccg ccaagcaagg ccgcaaaggc tggcgcatag agcatattgc
    57601 ctgagcgatc aaacagaatg ctcagcatgg ctcctagccc cacacaaacg aaatagaggg
    57661 cggcaaaggc gcctgttgtc atgatatctt taatggttaa ccctttcatt gtttacctcc
    57721 ttcaaaaaac catttctcac acaaaatagc tggtctgcac aggccaaggt ggatggccga
    57781 tgtgaaatca aaaagaccat tccccggcaa tgctttttaa tcaaatcaat aaagatggct
    57841 tcattcagcg aatctaagtt tgatgttggc tcatcaaaaa tatagcaatc cgcccgcttc
    57901 aatagagccc gcatcaattc caagcgctgg gcttcaccag ctgaaaagtc tgctgatcct
    57961 ctcactaggg tatctagccc ctcatcacag gctaggatac gctccttcat gccacaggcc
    58021 tcagcaagtt ccatgatatc atcatctgaa atgtccttac gaccaagtgt gatattgtca
    58081 cgaagtgttt gctgaaatag ctgcgcattc tgtgggacat aggcaaagtt agcctgtagg
    58141 gaagcagcat ttagcgtttg actgtcaacc tcactcagga aaatatgacc agcttgccaa
    58201 ttgtaccatt tcataatgat cttcatcaga gttgacttcc cagagcctga ctctccctga
    58261 ataccgataa tgcctttctt ttcaaaagcg acggataagt ggtggtaaat agtctcctga
    58321 tgcttgggat aagcaaaggt cagatcctca acagcaatcc ttgttaccga ggaaatacgc
    58381 tgatctccct tatctactaa cgcttcttca tctaaaagct gaaagacatt cctagcagca
    58441 ttcatggcac gcttgaagcc aagcggcaaa cgccccaatt ctaaaaaggg tgcaaaggag
    58501 gctgtaaagg caacaaaagc cagcaaccca ccagcaaacg tcaccgtctg ctgactcagc
    58561 tcaaaaagag taacataagc aaaggtcaaa atagacaagc caagagccaa aaaggttatc
    58621 gccatttgta aaaattgagc ctgtgccacc tgacgatcaa gcgcattaac atgcttgctc
    58681 tgattggata agagcttaaa gcgcttctca atgctttgaa attgcagcaa atccttaaca
    58741 gatctgagac tctctaaaaa gcttgacaca taagccctgc gcccttcatt ttgctttttg
    58801 agcagtgatt gaaggacgtt tgaaaaatac actggaataa taacagccaa aagcacatag
    58861 gtcacaatag cccccaaggc taacttccag ctaacctgcc aaaggtaata ggccatcaag
    58921 ctagctgaaa taaacgccgt acaaataggg gcaagcgtgt gggcaaaaaa gacctccaag
    58981 gcctcaatat cctcgccaat catctttaac aggtgcccgc tgtcctgact gtctaagcgt
    59041 gccggcgaga gtgctcttag ctttttaaag acaatcctgc gaaaggctgc caggctatga
    59101 aaggcaacaa aatgcccaaa ataatgctct ccataacgaa caagccccct tagcagtgcc
    59161 atagcaacaa atagataaag ccatttaaag gtaatagcat gaccagccat cacctctaag
    59221 cccagatagg ctaagctggt aggaatgcca acggtaagca caaagcccag cactgcaaac
    59281 atcaccgcca gagctatcca agccagcaaa tgcttcatca tagcaagcaa tcgtaaaact
    59341 agccggtagg tgctgtaatc actcttaacc ataaagattt gcctccaatt ctacttgtgt
    59401 atcaactaat tgacgatagg ccaaatgatg gcggtaaagc tctcttgggc tagccaagct
    59461 agcagactgc tcagggctta aaaagagcac ctgatcagcc tgcttcaaat atttcatctt
    59521 atgagtgatg acaattacaa tggcctgttt agccaattgc tgaagcagtc tgtgaatagc
    59581 agcttcattc tcagcatcaa gacttgaggt agcctcatca aaaatataac aggaacgctg
    59641 gctcaataag gccctagcac aaatcacctg ctgtctttgc cctgcagata agtgacagcc
    59701 attctcacct acaatggtat caatcccatc aggtagccag taaataaagc tcaaaatgcc
    59761 atgctcatca atccagctaa gcagctcctt tctagtcagc tgagctgcca tagcaaggtt
    59821 ctcataaata ctcatattaa gcagcgttga ctggtcagaa acgtagagta tttcctgatt
    59881 gatggcctgt ttagaagcca gatcaatcgt cacatcacca aggaatatct gaccgctatc
    59941 tgcctgatag cgcttcaaca ggagctgtgc aagactagtc ttaccctgtc ctgaaacacc
    60001 tgcaacagct gttagctcac cctttttgat agtcatcgtg atgtctctta gcaaagcctt
    60061 ttccccatgt gaaaaggaca aatcttgaat atcaatacga tcaaaggccg gtaaggcaac
    60121 tcccttgtct tggtcaacag cctcaacact atctaaaaag ccaaagattt gatctgccat
    60181 tttagtattc atcatgacta ggtgcatgcc atagccctgc tccctaatag gggcaaaaaa
    60241 ttccgttgca atcaggataa aaaagagaaa gtcaaaaaag gatataccac cagctgacag
    60301 agcctgaacc gctaaaaagc cagataagcc aatgccaaga tacatgacag cgtccatata
    60361 gccaaccgct tgcagctgaa agcccaagag ctgcatggta gccttacgaa aggcctctgc
    60421 cttattgaca aagctttcct catacctttc atctgcctga taggaataaa gggtatttag
    60481 ccccttgaga tcgtccataa atagattgcc aacgtccata taggttgacc agtaatggtt
    60541 catgatcctt ttagagcgtt tttgcatagc aacaatggat atgggaatca agggcaaaga
    60601 caagataaag accaagcccc ctataggata gatcaaaaaa acaagcagta agaccgttgt
    60661 gcaattaaaa gctgttagca ttgcaagcga taggtaatag gaataatagg tatccaagct
    60721 atcaatccct tgtgaggcaa ccgttaacac atcagcctct gttgactgct gatcaaattg
    60781 cccgtccata gcaataaagg catcaaaaaa ggattgcttg agcgagtcac gcgcaaattg
    60841 cgaagctagg ccctgcagct gctttgcaat catcgccaag ccaaagccaa cagcatttaa
    60901 aatcaaaagg ataacaagca gccttgtcaa ttgcagggct tgacctgcta aaaaggctgt
    60961 gaattgctta gcaattaagt aaaagctcat taaacgcatc aaaaattgca gccaagataa
    61021 aaaggccgac acataaagca aaaaacgctt aggagcaata cgctccttta aacgccttaa
    61081 aagcattttt ttctttgcgc gtgatatttt ttcagttgta tcgttcatat aatcgtcgcc
    61141 ttattcctat ctatcattca ttttttattt gtctcataaa gtggtaagaa caaatcgcct
    61201 atcctgcttt tcaataaagg gcaagctcac cccaaaaacc gcctccacaa aagcctgatc
    61261 aagaacctcc tgtggactgc cttgggcata gatggcacct ttttgcagcc caagcacaca
    61321 atccgaaaca gccaaggcct gattaatatc atgtaacacc atgataatgg tcattcctag
    61381 ctcctgattg atttttttga tgagggctaa aatgtccagc tggtacttaa tatcaagata
    61441 agtggttggc tcatcaagca ctaagacacc tgttttttgg gcaagcgcca tagcaatcca
    61501 gaccctttgc ttttcaccac cagatagctc ctgcatttcc ctaaaggcca attcccttag
    61561 attagtcacc tctaaggccc aagcaacaat gtcatcgtcc tcttgacttg atcccttaaa
    61621 aaaacgccga tgggcttggc ttgccacagc caccaaatca cccaccagaa gatctgctac
    61681 cgcctgatta tcctgatgca caacggctac tttttgggca aactgcttaa gactaataga
    61741 gctaatagct tgtccctcta agaaaatttg cccagactta acggggatat ttttagtcag
    61801 cagacctagt agggttgatt tgccacagcc gtttgccccc atgattgtcg ttatcttgcc
    61861 ttttggaatg gtaaagctca gcctatctaa aataggccta tcacgataag taaaggacaa
    61921 atcctctaca cgaatcaagc cttgctcatg actcatatca cgtcagacct ccttaacaga
    61981 taaataaaat aaggtccccc gacaatgctc atgataacag ctgggctaat ctccaaggga
    62041 taacacaact gccttcctaa ggtatctgcc agcaaaaaga caaaggcgcc aagcagggca
    62101 gaaaaaggaa tgagatagct atgcttactg ccaactaaaa ggcggccaat atgcggcaca
    62161 atcaggccta aaaatgacac cacacccaca atcgaggtgg aaacagcagc tagtaagacc
    62221 gcaaccaacg agattcctaa gcgcaggtaa ttactatcaa tgcctaaatt acgaatcaag
    62281 ccatcgttta gcagcagtag atcacactgc cttgctaggc ctatcgcaag cagcaggcca
    62341 agcactgtat aaggccacag cacaccaaca tctgcccagg ttttttgact aatatttcct
    62401 gacaacagcg cattgacaaa gggattgctg gtttttgaaa aatcagtaat cgcacgagac
    62461 aagcctaaaa acaaggcgtt gatagctatt cctgtcaaaa tgatgcgtat cggctgcaag
    62521 cccttcttcc aggacaaggt ataaatcatc aaaaaagaaa cacagcctcc cacaaatgat
    62581 aacaaaggac cataaaacaa gagctgcggc aaaagcaggc tagataacaa gaccataaag
    62641 ctagccccac tgcaaacccc aataatcgcc ggatctgaaa taggattttt taaaatcgcc
    62701 tgaaacaaga ccccagatgt tgctatcccc gccccagcca ataaagcaat cacaatcctt
    62761 ggaaagcgta aatcgtaaat aagggctacc tctgaatcat atgctacaaa taagccatta
    62821 aagatcctct gataagaaac agataagccc ccaacagaga ccgcatatag cattaaacca
    62881 aacagcagca tgagcaatag aaccatatag accagtctag tggtcctttt tcttgctgct
    62941 gtgacttgat cagaatattg actaccttgc tgcatcttac ttgacttcct ttgctccata
    63001 aaagatttgt gacagatggt tcaaagcctc tttgtagtta aacttagcac tcatgccaaa
    63061 aagggtattg tctaaatcat aaacctgctg agacttgaca gcttcaaaat gcttccaaat
    63121 atcattttca gcaaattcct tatcaaacat gtccttaacc ttgtctggaa tggcgtgggc
    63181 agtacgcaaa atcagctcag gctgctgctg aagcatgtct tctggattgg cagacaaaaa
    63241 ttccttgtcc tcagagtgat aaacattctc accaccagcc agctcaagca gattaccaac
    63301 ataggattta tttgtagcaa tcagatagct gccaggaagc cccatcaaaa taagaaccct
    63361 aggctttttt tgccctttat gctttttctt aaaggcccgg taaaactcct cataatcagc
    63421 ccgcaagcgc ttagcttcct ttttgcgatc aaacaagtcc cccaaatcat caatcgactg
    63481 gtacatgcct tcaaggctag ttaaattcaa aaagccatat tccgtatcca attgctggta
    63541 tttaggctct aaatcatttt gcagagaatt gggactgagt atccacgttg gctttagaga
    63601 agcaataacc tccatatcag gattcatcgg cagaccgatc cttttgacag catcgtaacg
    63661 ctttggcaat tggtatagct tactgtcaca gaccccaacc aaatctaggc ttagccgatc
    63721 acaaatatca acaacagcca cagaggtggc aacaattctc tccttatcag cctttttctc
    63781 tgccctaggg tgctgatcca cacaagcaga tagcaccaag gacaaaacag ctaatccaat
    63841 aagcttaatg actttcttca ttgttttttc tctttttctt tataaacaag accaaggctc
    63901 ctgacaacaa aagagctgtt ggtacatagt aaaccagaac tggcaatgga ttatttactg
    63961 gcttttggga cgactcttgc ttacttttat ctagcgaagt gctcaaacca actgcctgac
    64021 ccttcttaga gggatttgac tgttttttgg gactgcttga ttgaccaact ggccttgctg
    64081 agggattagg agctgacttg gcgtcttttg agtccggttt actaggagct ttcttctcat
    64141 ctgcctttgc aggagctgtc accgcatgat ccgtcttggc ttctcctgct gcaaagctag
    64201 ctaccatatc tccactgtag ccttcttgta gctcagatgg tgacaggtaa aagacaacct
    64261 ctctgcccat aggctctacg tacatgctgc ctctaacaac cgtattgaca tcaggcaaag
    64321 caatcgcaat atcctttgtt gtgccattgg tatcagtgcc aaccttggtg acactgtagg
    64381 ctgccgcctg aaaagcccct gtaccacccg gctgaaccca aaattggtag ttacctgaaa
    64441 aatcagctag actcatgcga aaggtcagat acaaatcccc agccgaggtt acctctagca
    64501 taccattgct ataaactgtt ccttccacca taccttggcc aatctcaaaa gcgtgctcac
    64561 caccgctatc ttcaatttgc cctgaaaccg ggtgacgata atctcgccta atcacacagg
    64621 aataaagctc acccttatca gcataggcct tacctcctat agctgctagg caaaccagca
    64681 ataccaccaa gccacccatt aattttttga ataatctctt tatcatatgt tcctcattaa
    64741 tgatcttcat ttccttacga caatcaaata aggcatagat ttagacgcag gccaagacct
    64801 actcttattt gactattata acacctcaaa tacgaaaagc atacccattc ctcacttacc
    64861 aagggtaagc ttaagaaatc attagaaaca ggcatgcctt tacgtatcgt tgataagcct
    64921 tgatgactac aagcgattaa accaagctct tagtgcatca aacagactct ctactgactt
    64981 aaaataattt tttcctacca agaatgagac caactgctat gacaataaag cttgctagac
    65041 cgataatgat atggccgcga tgatcagctt tcatctgctc ctgactatgt ttagcagcct
    65101 tagatttagc tttggctcta gtcttagcag cctgcttaga ggccttgcct gtaccagcct
    65161 tagacgcctt atgtgaagaa atcaggctct taagcttatc tgtaccggtc ttagcgtcct
    65221 ccttggcatt actgcttgga gcagctgact tcttagtcaa aagattggtc aaattaggaa
    65281 tagcaggact tgtatgacca ccaatgatac ctgtgtgagg ctgcaagagc tcacctatgg
    65341 taccatgtcc ctgattgtcc tctgagtgtg gcaattgtgc cttatccttt gtcaggcttt
    65401 gaagatccaa cttcataaag actgtctgga agcctgttcc cttagagata gcgtccataa
    65461 ttggcacaaa gacgcgaaga ggtaccaagc catccttttt agcctgatca atcagcctaa
    65521 atctcaacac ctgtgggtaa ttgctgccat aagcgtctga caggggcttg cctgtgacat
    65581 ctgtaaagta ggacacaacc tctgcttttt ctgtcttacc aaccggtctg ccagtcaaat
    65641 ccctttggta gccatcaaca aagtagctca actctccgag ataccctgtc aggttaccga
    65701 tcttcatgcc cttaaaggtc acctctaggc tatagacacc cttattcaca atcaatttga
    65761 cgcggtggtc aatagcctga tgagacattg attctgactg caaatcattt ttaagcatgc
    65821 ttgccttgat gtagtagaca ccatcttcaa gcttattaat atccaagccc ttagactggt
    65881 cactacctgc aagctgatcc tccttgacct caacatcatt agaggtcaga taaatatgct
    65941 cacgcttctt agcaaattcc ttggtgataa gagccttacg aacacgataa acacctgctc
    66001 cctttaggtc aaaggagcct tgaagctcat cttgtggatc gttattcaag cgtctctcat
    66061 caacggtgac atattgaccg gttgatgttt ttttctgcaa ttgcaccaca atatcccagt
    66121 cagcataacg ctcatttaat aaggcaatga tgtctgacga gcttgcctta aggcgtttat
    66181 tgtaatcctc aacagagcta atttctgctt cggtgcttga gagtgtctgc tgctcccaat
    66241 aatacaaatc aagcaggcta aacccttggt gataggtcat cgcttgatga tttaaagtcg
    66301 cagatagatt agcaaattgc ttttgtgggt ttagcttatt tgttcccatg atctgtctaa
    66361 gcttatcact aacgccactt aggcagttaa acttaagatc aagatccaat gcctttagat
    66421 ctgcaaaatc agcttcgcta atattcgtta aaaggttatt atagacatta agctttgata
    66481 gctgcttatt agccttgaag gctccctgtg ggattttagt tagctcattt gatgccaagt
    66541 caacggttaa taagtttggc atatgactaa agtcaatatt agcaatatct aaaacctggt
    66601 ttcgattggc aacgatataa gaaagcttag ttagcttact caaggagctt ggcaggctgc
    66661 ccaactggtt ttcagaaaca tcaaagaagt ttagattatc aagtgaagct agagcatttt
    66721 ctgaaaattc agtaatgata ttttcagcca aggccaagga ggtcaagcga gatagaccat
    66781 taaagacacc atctcgaatc acgctgattc tattttttga cagatctagc tgatccagct
    66841 gaccaagatt tctaaatagt ccttcctcca gatttggcat atagttgctt gagagataga
    66901 gctcttttag ctggctgtta tgagcaaagg tatccttatc tagggttgta atcacattgc
    66961 tgcgaagatt taagaacctt agattggtca tttgactgaa ggtttccttt ggaatgcttg
    67021 caatctgatt gccctctaag tgcagctcag taatatgctt agcatgcttt aagagtgaaa
    67081 tatctgtcaa atcatagtgg tctaggcgca gctcaccttc aatcttcgca atttcctcag
    67141 gtgacatttt gccatcaccg ttaaggtcct taccaagctt aaccaaaacc ttttcaagac
    67201 gctcagagcc gacccctttt tccttgtcgt caatctcagc ctgatagcct gtccagccct
    67261 tacttgctgt agcgctaaag gtcatgtcca acttggtgta tttgtcatag tgatgtaggt
    67321 cgctttcctg accacccata gctgatacta gcacagcacc cttgtgaagc ttgtccagct
    67381 cctcaatcgg tagggtaaat tcactctaat gtagttattg ttaatatcgc gttcaccaac
    67441 ctgagtgcgg acagaggttg gatactgccc tttactctca atggaaaagt caatcaaaaa
    67501 ttgccctaga gctgtattga gcaatgaaat ctccatcttg ccatcttctt tgacgaccag
    67561 cttggccttc ttatcaaatg ctccctgcag cattgaggct tcctctgtat tttccttatt
    67621 ggccttaaag gttaaggtat aggttcctgc ctttagatcc gtaacagcca gatcagttcc
    67681 ctgataggac ttgatactat ccatcaaaag ctcataggtc tccttgagca atttttcatt
    67741 gtcaatctga cgataggact ccttgatcac ctgaagcttg ctagacaagt ccttgacctg
    67801 ttctttattg gcctcgctag caatgatacg ctcagcttcc ttgatcgcgc tttccagctt
    67861 agtaaaatca agtccctgcg gtgcttcctg ctgggatcct tgtctctgct tttgcttagc
    67921 agaaacaaag gtgtattgct cccctgactt tttcactgta atgatgacat cttcaaagct
    67981 ttgtgaggaa atgacaacct tgttttctcc ctccttgaaa gctgtcgtcc caagatgaag
    68041 ccccttcagg tcagacacat agccaggctt gtcctttact gaatcataga ccaaatcctt
    68101 atagtcctgg tcattgacct tgatctttgt gatttgatga gctaattcct taatttgctt
    68161 ggtgctggaa tagcgatcaa tttccggaaa aagaagctct ccttctgttg tctctagttt
    68221 ggtgataaat gatagggtcg ctaagccatc atggctagtt accttagcag gcttttctgt
    68281 cttagcagca gcttgctgcg gtgaagcagt agtatcatct gaaggcttgg cagaaacaaa
    68341 ggtaacatca tttcctttct tgtcaaagac cacaagaatg cctccgttag tcttattgac
    68401 gatgcgcagc tgatgctgtc cttctgtgat gttcttagcg tttaccttga ttccttggta
    68461 attgatgtca tagctatagt caccctccag ctttttgtca tactctttac catcaatgag
    68521 aattttctcg atatttttat aatagagctt cccctctgac ttgtccgcat agggaccgat
    68581 ctcctcgaac aataaaatat tatccttaag cttgacagtc gtcacaagac ttgaagagac
    68641 ttgagtagcc tctgagcgaa ccgtctgggc agactgggca agagccagcg ttgataaagc
    68701 aagaatggcg cacttattga tacttttcat tatttcgaac cttctaaaaa tgttattagc
    68761 catttaatta ttttattaat ctcacttaat ttattatgtt gtcaagcctt tgtcaagatt
    68821 gaatttgaga tttttttcac aataaagcaa agaaaaaaac agccctgcaa cagagctgga
    68881 ttttttctta caaaaattct gtacttctcg cctttaaagc aagaagatta cttatgattt
    68941 tccaacaaca taagtcaatt ggttggcctg ctcagcagta aaggtgcggt atgaaatctg
    69001 acctaagcca agacaatttg actctgaaat caggatggag ccgtcctttc tgacatcctc
    69061 aacaatagag acgtgcccat aaagaccgtc agcacccgct tgacctggag caaaggaaac
    69121 cgcatagcct acctttggct ccttagaaat actgtagcca gacttaaatc tccagtcacc
    69181 accatttccc ataaaggaat caaactgata gcctagctcc ttagcgcgat tataaacata
    69241 ccaggtacat tgtccccaag catagcttga cgcctgatag cttaaaatat catagctctt
    69301 agacagcttg tagcctgtag gaacaacagc aaagcttgaa gaggattgaa ttttcagctc
    69361 agccggaatc tctggcgtgc ctccatgctg atcaatccaa gcatctaatt tttccatgat
    69421 ctcagcgcga cgcttgccaa tgccattggt atctgtgaag taaagaccac catcactagc
    69481 aaagttcaac tgctttttgg caaatttatc agccttttga tcctgctgct caaaattaag
    69541 gttgctattt ttgataatcg tctcctgtgt cagcttaaca atagcaagct catcattaaa
    69601 ctgatttggc tttttcgaat caaggtcaaa aagcgcatag ccaaacatgt tagagcctag
    69661 taaggttgca tttcccttgg ttcctagctc actttctgtc attgcaatgg ctacaatcgc
    69721 ccgcacatct agcccactct ttttttccca ttgcagcaag gcagcaccgt taattcgctt
    69781 ctcatcatac ttgatcttgg tagactttaa aaagctatca agctgctctg ccttgatccc
    69841 atagcgccta gacaagaggt tatgggtata agcactctga ccactccaat gcgtcacata
    69901 agcagcatag gtatttacag aaggcagggc cagagtcaag gacaaatcaa ctgtaggagc
    69961 agcaggaaca atattcagtg ccggctgaga tgcctgtgta gcaacttcag gggctggctg
    70021 agggctagct gctggactag taggtgtcga ctgtccagta gaaccagaag ctgatccaga
    70081 gctagctgta ttgcttgatg accccgttgc tccaggttct ccactgttgg gagtagtctc
    70141 agtggttgat gaggagttgt cagtagctga ggtagcagct gctgtcgaag tggactcacc
    70201 agtctgggcg attgcagcct cattagcagt agctggaacc tggctggctt cagctcctgt
    70261 atcctctgcc aatactcttg cggtctctaa atgaggtacc agaagagtca tcagcattat
    70321 cattcttaat aatttatttt ttctcattta gtattcaatc acttctttct gctctattct
    70381 aaccta
//
LOCUS       DARYXS010000002        50113 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.002, whole genome shotgun sequence.
ACCESSION   DARYXS010000002 DARYXS010000000
VERSION     DARYXS010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50113
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.002"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(323..682)
                     /gene="rplT"
                     /locus_tag="TV193_000066"
     CDS             complement(323..682)
                     /gene="rplT"
                     /locus_tag="TV193_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEL1512310.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLGK"
     gene            complement(743..940)
                     /gene="rpmI"
                     /locus_tag="TV193_000067"
     CDS             complement(743..940)
                     /gene="rpmI"
                     /locus_tag="TV193_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEL1512311.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKAMVTGL"
     gene            complement(980..1510)
                     /gene="infC"
                     /locus_tag="TV193_000068"
     CDS             complement(980..1510)
                     /gene="infC"
                     /locus_tag="TV193_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEL1512312.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     ANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     misc_feature    complement(1525..1647)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(1671..2351)
                     /locus_tag="TV193_000069"
     CDS             complement(1671..2351)
                     /locus_tag="TV193_000069"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEL1512313.1"
                     /translation="MKAIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALKNGYHKEDVNLILQELAKRPISFKKAADGSQLVFLGDQDVTMAIRQNDVTNNVSWV
                     SALPEIREELVNQQRRIARTGAIIMDGRDIGTVVLPDAELKIFLIASVEERAQRRYQE
                     NIEKGIAADFDTLKAEIAARDYKDSHRQVSPLKAADDAIIFDTTGITISAVVQFIQEK
                     AEKIIDMA"
     gene            complement(2366..2863)
                     /locus_tag="TV193_000070"
     CDS             complement(2366..2863)
                     /locus_tag="TV193_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEL1512314.1"
                     /translation="MAKEPWEEKIVDDNKATRTRKSRGALISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNKQNETTGFYGASTQKKTTKKVSSKPKTKPKASSNSSAASDTTS
                     PSKTETAPSTEAAGKTITVLAGEGATSIAARAGISVEQLQALNPDHMTQGYWYANPGD
                     EVNIK"
     gene            2912..3109
                     /locus_tag="TV193_000071"
     CDS             2912..3109
                     /locus_tag="TV193_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEL1512315.1"
                     /translation="MKVSILPEKCIACGLCQTYSALFDYHDDGIVKLAQSDESSQLID
                     PNDHDAILAVKSCPTKALTLE"
     gene            complement(3096..3584)
                     /locus_tag="TV193_000072"
     CDS             complement(3096..3584)
                     /locus_tag="TV193_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEL1512316.1"
                     /translation="MIKLFGKVRYHWQPELSWSIIYWSIAVAPIFIGLSLLYERTEIP
                     SRVFVLFALFAILVGLGLHRYFVIENNGVLKIVSLKLFAPHRLMIASITKIEVTKSTV
                     CLFVGDKSYLFYMRKWPKKYFLDDLAINPYFKGEVILLDNFIKLDYFEAYQYEKKPLT
                     RG"
     gene            complement(3629..4852)
                     /gene="pepT"
                     /locus_tag="TV193_000073"
     CDS             complement(3629..4852)
                     /gene="pepT"
                     /locus_tag="TV193_000073"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEL1512317.1"
                     /translation="MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPE
                     MEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQ
                     GGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVA
                     NPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALE
                     LKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEE
                     AQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMT
                     PVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MEKAVDVILGIVQKA"
     gene            complement(5022..6041)
                     /gene="galE"
                     /locus_tag="TV193_000074"
     CDS             complement(5022..6041)
                     /gene="galE"
                     /locus_tag="TV193_000074"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1512318.1"
                     /translation="MLGSILVTGGAGYIGSHTCVELLAAGYDVVVVDNLCNSNPKSLA
                     AVASIAGREVTFYQGDIRDQQLLTDIFSKHPIVSVIHFAGLKAVGESSRIPLDYYDNN
                     ISGTLTLLKVMTAFNCKKIIFSSSATVYGDPHTVPILETFPLSVTNPYGRTKLMLEEI
                     FKDLYASDNEWHIVLLRYFNPIGAHESGDLGEDPKGIPNNLLPYVSQVAVGKLDCVGV
                     FGDDYETKDGTGVRDYIHVVDLAKGHVAALAKFAEEPSLSIYNLGTGTGYSVLDIIEA
                     FSQVVGRSIPYKILPRRQGDIAACYADASKAKKELNWTAEYGLERMCTDTWRWQSKHP
                     NGYED"
     gene            complement(6109..8478)
                     /locus_tag="TV193_000075"
     CDS             complement(6109..8478)
                     /locus_tag="TV193_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1512319.1"
                     /translation="MLDMILFSLSSLYLSIFAVSKNTLNKGAYGSWLVLVLIAGMACL
                     LIKHASSKLLIVSVAVSSYYAVANSYITLAINKNNSRFTISNRTIQEMLLSLAALVSL
                     LILGVLLKKYLFKKDYQSNRGIQVILLSQAFSVLTLNSSLFKTVIKQNDYWPLDSQSN
                     LVSLNLFKYSFCSYMLTFVVYYLIVTAFIEVLSKRWGLRLALVTSLFLGIIFNYFIQA
                     GITAYGDFHGAVIIPGATLFQVLVLTLFFVLVFLLINNYIIALFVNTVIGALISIVNI
                     EKYKQRSEPLLFSDLKWIKEIKFFLNYISLTQIISIILILVLSGLLIYVLYKRYFREK
                     ILSALYLRLMSIGSILLVFASILFVFSQNKDGEIKKGIPVLSSVYNVFDIDWYGLTTN
                     ARFQSLSFVWFKQVTTSTINQPSGYSKSAMQKIYQKYQARAADINKQRHQRISDQTVI
                     YILSESFADPARISGVQLAKDPIAEIHHIMETTTSGLMTSDGYGGGTANMEFQSLFGL
                     PKYNLNPTVSILYSDVFPKLKFSPAISNAFSPKDRIVLHLASANNYSRKIVYNKLGFD
                     TFIATEDSADKPKHLIRMSSSYSDESTYDNILDQLNPKRSQFFSVITMQNHGPWYTEL
                     RDVDVSLAGLDQSETDSLQSYVNLLSITDKSTKAFLSALEKVDKPITVVFYGDHLPGF
                     YPDQVFKNDEEVKYLTDYFIWSNHQTNKLARPRVNSSDFTSLLLEHTDSKVSPYYALL
                     TDVLDTRNSDDSQLTAAQKQVASDLKLLEYDLIEGKGYINAYPDFFKMK"
     gene            complement(8558..9721)
                     /locus_tag="TV193_000076"
     CDS             complement(8558..9721)
                     /locus_tag="TV193_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1512320.1"
                     /translation="MKTIAIFSGFTSPHLGGVERYTEKIAQQLVSLGYRIIIVTSNSH
                     QLSPIERDQAITYYRFPSKQLFKQRYPILDKNDLYHSMLAELMEERIDFVICNTRFYL
                     TSLMGLKLAKRKAIPSIVIEHGGGYVQVGENVKGHQLLDLFAKVYEHVITFFVKAYQP
                     DFYAVSKRSMAWLKTFGIKAKGVIYNSVDSDLYEVFKSKAYLPALQDKVIITFAGRVI
                     KEKGILLLLEAFEQLTYKDRAVLVVAGDGPLLASLRDSYKEDQSIIFTGKLNFAETMS
                     LLSQSDIFVNPSIYAEGLPTAVLEAGMLKCAVLATDRGGVKEVITSPSQGIIIDDTVS
                     DIKRQLDHLIEHKEKRCDLQEAIHQQVLSGFTWEVTVRQLVTEVIASESESNV"
     gene            complement(9735..11219)
                     /locus_tag="TV193_000077"
     CDS             complement(9735..11219)
                     /locus_tag="TV193_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEL1512321.1"
                     /translation="MLDTLFDKLQKASKALLVLLGAFLVLLLLYTQSTDLPIKFLAIL
                     VAIAALLIIFLPSNMEYATVLIIVVMGSVSAFISPINDIPDERVHFARALYLSEGNLN
                     LTNDDSKLLVTDDINLMDHNNGKPLRFQLWSRDHTDEAISFKEIRSTNGYYNFAYIPQ
                     VIGLFIGRSLGLTMGLSYLLGRLCNVLAYAILVFVALRLLTAGKQLLAVGSLLPMNIY
                     LAGSYNQDCVSIGLIILTISLFVQMATTEKIPLSKLFWYTLLCSIITFTKLPYILLIL
                     LLLFIPSRQFGAKASRTFLLKLLSILTVLVVTVFWLKVYGQIKSPQVDMADFLQKVNA
                     KEQLLTVLRNPIVYGFMLLRHTLAHILNPSGIYMFGPLSYGMVELMPISMVYYFAVVI
                     TNANKLQLPTLSRFGMGLMSLGIIGGITFSLYLTFTPVGDLNVLGVQDRYFLGVIPLV
                     LVLLASNNKYLEKAQGLLSNKQVLIGSLLLILGMITRTMLQYYT"
     gene            complement(11223..12464)
                     /locus_tag="TV193_000078"
     CDS             complement(11223..12464)
                     /locus_tag="TV193_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEL1512322.1"
                     /translation="MKTSSRIQSDQSIFIWNVLGTSSTALISVILLMIVSRVLSKSAS
                     DTFSFAYAIGNQLITIGLFQIRNFQSTDILHKYRFKDYFYTRLVTCFLMIAISVLYIY
                     LGSYSGFKGLVIWLICLYRCTDAISDVFQGMFQQRERLDIAGKSLFYRNMLVILGFTL
                     CLVLTKQLVLSLIVICLISVACIVLFDITPSVSFTSLERRIDAQSILGLLKESFPLFL
                     NGFLLIYIYNQPKFVLEQLYSKQLIPAGVQTEFNILFMPIFMINLIFLFLRPMITQLA
                     IYHSKEDEKSFAQLERRLSLVLLLASLAILLASYFVGLPVLSLVYGIDLRHYQLDFML
                     LIFGGIISTFATYIDNLITIIRKQHLLVIPYVVSFISSLAITGSLARSFGVIGVTYGF
                     IISMMIWLLLSYGLYIMEKRK"
     gene            complement(12448..12804)
                     /locus_tag="TV193_000079"
     CDS             complement(12448..12804)
                     /locus_tag="TV193_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEL1512323.1"
                     /translation="MFIGLQLILIIVALLTAMFILDSIRRSKILIEDSFFWLFFSLIV
                     LLLSLFPNAAVYFSRLLGFESPANFVFLSIIFLLIINQFFITQKLSRTEIKLKKMIQY
                     LALNEKEKQEEDENQQ"
     gene            complement(12809..13498)
                     /locus_tag="TV193_000080"
     CDS             complement(12809..13498)
                     /locus_tag="TV193_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1512324.1"
                     /translation="MKKDLLVMIPAYNEEESIEKVVENIKRHFPQYDYVIINDGSSDR
                     TSEICHHNHYNIIDLPENLGLSGAIQTGFKYAFKKGYAKALQFDADGQHLPEYIEALS
                     DSINAGADCVIGSRFVSAEKNRSLRMIGNSLISFFIKLTTGKRITDPTSGMRMFNQEL
                     IRIFATNINYTPEPDTISYLIRQGYRVSEVQVQMNDRLAGQSYLTLSRSIKYMVHMFI
                     SIILIQNFRKR"
     gene            complement(13528..15273)
                     /locus_tag="TV193_000081"
     CDS             complement(13528..15273)
                     /locus_tag="TV193_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEL1512325.1"
                     /translation="MKRLLLYVHFNKYHKVSDHVYYQLEQMRALFSKIVFISNSDIHQ
                     EDLEQLEQRHLMDQFIQRHNKGYDFAAWHDGMKALGCEHLVDFDSITIMNDTCFGPLW
                     DMKPYYLKYEADEAVDFWGMTNNRATKAFKEHIQSYFISFKKSLVHSKEFRQFWENIV
                     ELTDVQDVIHNYETRITTVFVEAGFRYKTVFDTTKEDSSSMLHADFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLDFIDQKTTYPASLIVDHMSQVHPPDAKYLLAHKYLPEQ
                     PISIDQSKKIAVHLHVFYVDLLSEFLEAFSHFHFDYDLLITTDSKAKKAEIKEILRES
                     GASADILVTGNIGRDVLPMLTLKERLSQYDYIGHFHTKKSKEADFWAGQSWRTELIDM
                     MVKPADQILTALAADAIGIVIADIPSFFRFNKIVDAWNEHLIAPEMNQLWQAMGLTKR
                     IDFQTMDTFVMSYGTFVWFKYDALKPLFDLDLSEADIPAEPLSQNSILHAIERLLIYI
                     AWDRHYDFRISRNEKLLTPFIDNKLLNLREGSVPHTYVDFDYMGGIKGALKYIVIGPA
                     KAIRYIIKRLLKRRV"
     gene            complement(15270..16277)
                     /locus_tag="TV193_000082"
     CDS             complement(15270..16277)
                     /locus_tag="TV193_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1512326.1"
                     /translation="MKKVSIICTNYNKGPWISEALDSFLAQQTSFDVEIIVIDDASTD
                     YSRQILMDYQASFPDRIRLIVNEVNLGIARTWVKACLEAKGQYIARCDGDDYWTDTLK
                     LQKQVDLLDSSPDSKWSNTDFDFVDTDGKLIQSNAFESGFTPLTDTYEKMLALKGMTM
                     SSTWLVEADLMRAVNQRIDLETSDDTFDIQLELFQSTSLAYLKDSTTVYRMTDNSDSR
                     PAAEEKMLGRIQGLLETQLSYLSKYPTANMEAIAKALLKQDAKNEIRIHQLSHTIHQL
                     RQTLADQEALQAEKIDQLQQQLDHQRQEVEALTHQYNCVVTSRRWRYLSKLLELFRRK
                     K"
     gene            complement(16298..17506)
                     /locus_tag="TV193_000083"
     CDS             complement(16298..17506)
                     /locus_tag="TV193_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512327.1"
                     /translation="MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQ
                     HVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYC
                     NRAVLIENGLVKAYGEPFDVANQYSVDNTELKNAEQGAAAEPVSDLASQLEVRLTSKP
                     SLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQ
                     CQLSHLNDIKLKLEVTVRDQNGQMLLFLTANHSPLVVLQRNDIAPDDLSALDSASGLY
                     QRNGSWLINQ"
     gene            complement(17506..18309)
                     /locus_tag="TV193_000084"
     CDS             complement(17506..18309)
                     /locus_tag="TV193_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1512328.1"
                     /translation="MELLSKKNRILLKELVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRTGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     TIVFSAVLGALINFSINLLVVLVFAAINGVTLSPHAYLALPLFVELAVLTVGVALMLS
                     TVFVYYRDLAQVWEVLLQAGMYVTPIIYPITFVFDRHPLAAKILMLNPLAQIIQDLRY
                     LLIDRANVTIWQMSTNWCYIIIPYLIPFVLLALGVAVFNKNAKKFAEII"
     gene            complement(18309..19244)
                     /locus_tag="TV193_000085"
     CDS             complement(18309..19244)
                     /locus_tag="TV193_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1512329.1"
                     /translation="MKINILMSTYNGARFLAEQIQSIQRQTVQDWTLLVRDDGSTDKT
                     LAIIQAFAKKDPRICLINADVQENLGVIRSFHTLLTYEKADIYFFSDQDDVWLDNKLE
                     LTLAEAQKHKISEPLLVYTDLKVVNQDLEVRHESMIQTQSHHANTQLVQELTENTVTG
                     GTMMINHALAEQWVSCEHVVMHDWYLALIAAAQGELVYLDVATELYRQHDANVLGART
                     WSKRLKQWRKPHKLIEKYWWLIVSSQHQARQLLDLQLNPADRRLIEAYVGLLDRPFYQ
                     RLSDFKAYGFRKNRAFHTLVFMALIMTKFGYRRKE"
     gene            complement(19234..20388)
                     /locus_tag="TV193_000086"
     CDS             complement(19234..20388)
                     /locus_tag="TV193_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEL1512330.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELVTNQTNKSITYHIACLSD
                     SKHKEHFVYKGADCFYINPPKLGPARVIAYDMMAISHALAYIDRYHIQKPIFYVLGNT
                     IGGFIAPFAKQIHQRGGRLLINPDGLEWKRSKWSKPVQQYLKYAEKQMTKHADLVISD
                     NIGIEAYIKKSYPWAKTTFIAYGTEIGRSCLSTSDEKVRTYFQTFEITENQYYLILGR
                     FVPENNYETAIREFMASSTQRDLVIICNHDKNPYFERLVSATGCDKDARVKFVGTQYD
                     KQLLAYIREHAFAYIHGHEVGGTNPGLLEALAHTQLNLVLGVTFNQSVAKTAALYWTK
                     EKGSLTGLINRVDQKESFADLGERAKQIIAKEYTWEKIVGEYEALFLDED"
     gene            complement(20513..21361)
                     /gene="rfbD"
                     /locus_tag="TV193_000087"
     CDS             complement(20513..21361)
                     /gene="rfbD"
                     /locus_tag="TV193_000087"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEL1512331.1"
                     /translation="MILITGSNGQLGTELRYLLDERSVDYVAVDVAEMDITNATKVEE
                     VFAQVKPSLVYHCAAYTAVDAAEEEGKALNEAINVAGTEHIAKACERYGATLVYISTD
                     YVFDGQKPAGQEWLETDTPDPQTAYGRAKRLGELAVERYTKQFYIIRTAWVFGHYGKN
                     FVFTMQNLAKTHSRLTVVNDQHGRPTWTRTLAEFMCHLADNRKPYGYYHLSNDAKEDT
                     TWYDFAREILKETAVEVVPVDSSAFPAKAKRPFNSTMNLDKAKATGFVIPTWQEALEA
                     FYKQQQ"
     gene            complement(21503..21841)
                     /locus_tag="TV193_000088"
     CDS             complement(21503..21841)
                     /locus_tag="TV193_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEL1512332.1"
                     /translation="MTETLKYTEEQVAAIKDRILEALGTVIDPELGIDIVNLGLVYEI
                     RFDDNGHTEIDMTLTTMGCPLADLLTDHIHDAMRDVPEVTKVEVKLVWYPVWSVEKMS
                     RYARIALGIR"
     gene            complement(22139..23248)
                     /gene="rpoD"
                     /locus_tag="TV193_000089"
     CDS             complement(22139..23248)
                     /gene="rpoD"
                     /locus_tag="TV193_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEL1512333.1"
                     /translation="MAKEKEITTFNVQIAEFIRHHKKEGTATDDEVTEKLVIPFTLDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYVVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSDEEKVLAVAVAAGDMEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(23257..25071)
                     /gene="dnaG"
                     /locus_tag="TV193_000090"
     CDS             complement(23257..25071)
                     /gene="dnaG"
                     /locus_tag="TV193_000090"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1512334.1"
                     /translation="MGFLWGGDGLAIDKEMISQIKHNVNIVDVIGEVVHLSRAGRHYL
                     GLCPFHKEKTPSFNVIEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIVADKAGM
                     AVTVAPSQTSLSQKQHPHQALIDLHEDAAKFYHAVLMTTKIGQRAKEYLYQRGLDDQL
                     IEYFRIGLAPNEMDYLYQALSKKYTEAQLTASGLFHVSEQSNAIYDAFRHRIMFPLCD
                     DKGNMIAFSGRIWAREDIEKQQAKYKNSRATVLFNKSYELYHLDKAKPIIAKTHEVFL
                     MEGFMDVIAAYRAGYGNTVASMGTALTPEHVRHLKQLTQKVVLTYDGDDAGQNAIAKS
                     LELLADFQVEIVKIPNRMDPDEFVQQHSPEALAELLQHSRISSVEFLIDHLKPENMDN
                     LQSQIAYVEHISQIIAQAPSITAQNSYINKVADLLPDFDYFQVEQSVNALRLQDRQSL
                     QQGQASQPKASLVTLPINKSMTALAKTESHLLHRLLHHDYLLNEFRHRPDFYFDTPAL
                     QTLYEQLKATGQITSYDLSQLSEEVNQAYYRVLEENLPDEIASGEIEDILSRQMTLLK
                     QRELHRQGKQIRESSSKGDHQMALEALERFIAEKRKME"
     gene            25318..25692
                     /gene="mscL"
                     /locus_tag="TV193_000091"
     CDS             25318..25692
                     /gene="mscL"
                     /locus_tag="TV193_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEL1512335.1"
                     /translation="MLKELKAFLFRGNIIDLAVAVIVGSAFSAIVTSFVNDIITPLIL
                     NPALKAANVENIAQLAWNGIKYGSFLSAIINFLIVGTSLFFVVKVAQKAMPKKGEEEP
                     AKPKTPTQEELLLDIRDLLAKK"
     gene            complement(25918..26094)
                     /locus_tag="TV193_000092"
     CDS             complement(25918..26094)
                     /locus_tag="TV193_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEL1512336.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(26249..27061)
                     /locus_tag="TV193_000093"
     CDS             complement(26249..27061)
                     /locus_tag="TV193_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1512337.1"
                     /translation="MNMKRLLVGALAMVSVFALAACGQANKTSLQDRIQEKGKLVVAV
                     SPDYAPFEFKALVDGKDTIVGADIELAQAIADELGVKLELSAMNFDNVLSSLQTGKVD
                     IAISGLSYTKERAKVYDFSEAYYETENAILVKASDAKHYANKDSLVGKKVAVQKGSIE
                     EGLVKEQLNKANCVSLTVMGEAINELKSGQVQAVDLEAPVAAGFLAQHKDLALAPFKL
                     QASDGDAKAVAMPKGSDDLRQTINKVIKQLNKDGKYKAFIQEAALLTGNAVE"
     gene            complement(27129..28244)
                     /locus_tag="TV193_000094"
     CDS             complement(27129..28244)
                     /locus_tag="TV193_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEL1512338.1"
                     /translation="MKLPVFGVEEWLNQHEKRAVYDIAGSSIASLTLEELFDLTQEQP
                     QAFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLE
                     AGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMIN
                     NANNPTGAYMTKPYLEELINIAREHDIYLLSDEVYHSFTSDHLLAVADLYDKGITVNS
                     MSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRN
                     QAIIRTNLAILEDWITGEARASYHRPNEVSTAFVRLDIDEDMEAFALRLLEDYGTLVV
                     PGNRFNQANHVRIGYCCQPQVLQAGLSRLSQCLKNIQ"
     gene            complement(28514..32155)
                     /gene="addA"
                     /locus_tag="TV193_000095"
     CDS             complement(28514..32155)
                     /gene="addA"
                     /locus_tag="TV193_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEL1512339.1"
                     /translation="MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNI
                     LVSASAGSGKTFVMVERILDKILRGIPVDCLFISTFTVKAATELIERIEKKLHTAIAE
                     TQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRIIQDKAEQDIL
                     KREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSW
                     LAEVFLRGSKTYTSFTDIPDQAVDALLACMQDTADQLRDLTDMEGYAQTTKAGKLTAK
                     YTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQ
                     EQLVRFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIE
                     ILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYD
                     DKHQLVAGSEGQRQPYPNNRAQLLLYDTDQVQEGTEEALANDGISAGEVILVAKEIIR
                     LYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTL
                     RSINNPLNDYALVALMRSPMFSFDEDQLARISLQGSSQKQPQAFYDKLSNSLRGQGEH
                     PELIGQELMTKLADFDGTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQ
                     ANLYALAIRADQFEQSGYKGLSRFIGMIDKVLETQNDLADVEVERPKHAVNLMTIHKS
                     KGLEFHYVFILNCDKRFAMADLQAPIILNRDEGIGIKYVANVKELLREEKLASLKVTM
                     ETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLIGKASKEKVQEKTADNSSEGR
                     LALASRERLLSFQDWLLAIAATFSKEDLFIDVRFVDDSDLTPEAVGQLRPSGLLQADD
                     LKDNRQTEDIARALDMLDKVSELNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDII
                     DQPYHRPKTFELPDFSKKKAVEPSQVGSSLHELMQRIPMSDQVTAGDIEQTLQLVSAD
                     AEVKARLDIEKVTSFFATTELGQLLQEHHQRLHREAPFAMLKKDSLSQEQYVVRGIID
                     GYLLFEDRIVLFDYKTDRYQQSAELKQRYQQQMDLYAEALSQSYGIARIEKYLVLMGG
                     SQLEVVRLA"
     gene            complement(32145..35366)
                     /gene="rexB"
                     /locus_tag="TV193_000096"
     CDS             complement(32145..35366)
                     /gene="rexB"
                     /locus_tag="TV193_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEL1512340.1"
                     /translation="MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKER
                     SVLALLPEQGSFAITVTRFEQMARYFTLAKAANRQALDDNGLAMIFYRVLMQLQEDEL
                     KVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQ
                     GDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEEQLLALLNEACEEIVI
                     GAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLE
                     ANHDYSKLDWQLSAKDKSKVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGD
                     VASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKS
                     GLFGRFQEGELDQLEQYLVFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQ
                     QLFKSQKQLGASLLDKLMTFFKTIQLADNFEALAGSRRETDREKDEEVWKAFTGILET
                     FYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIG
                     LSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNAATQ
                     ELVLSLPTSLTNSSDDVSPYLKELIALGVPVIEKGKNRLSHSAADIGNYKALLSRLVA
                     INRQGIADDMTSEDRNFWTVALRYLKRRLADEQLSLPAFEHHLTTKPVAPEVIETRFS
                     SQQPLNLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDR
                     SNAAFDQKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTASVLDLNQGLQI
                     TKQEEAFELALGQQVLIRGVIDRIDQLADGRLGIVDYKSSARVFDIVAFYNGLSPQLV
                     TYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKALDDQLVAAAYKELTYKGIFLAQAKE
                     YLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQ
                     LKAITRFEADLDLGYARRLVVLPTKERRQAFLTRMNEEIKHED"
     gene            complement(35575..36975)
                     /locus_tag="TV193_000097"
     CDS             complement(35575..36975)
                     /locus_tag="TV193_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1512341.1"
                     /translation="MIVQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGTIHLYERRQ
                     QAPVGGDVSLPPVSILVPAYNEELTIIETVESLLMLDYDCYEIIVIDDGSTDHTAKLL
                     KEQFHLEAVTCSINQRIPTRPLKAVSQKQLKHIKLTLLEKANGGKGDSLNLGINAAQY
                     DYLLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQ
                     LISCAQAIEYDCAFFGARVLLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDME
                     LVMKLHFFCHNNKIPYRIGYETDAICWSQAPSRLKDLCRQRRRWFLGLYQCLKKYLQF
                     FVSCRFKATVLISYVLYLLFELLSPFIEAFGVIIIVLSLLCHQLNTTFFVSLMLLYIC
                     YCVLIALTSFLNRVYLQNNSSITLFDMAWVIYAAIYQCLVLHTVLTLIKVSSFIGYQR
                     KKNAWGQITRDKHRAA"
     gene            complement(37117..39258)
                     /locus_tag="TV193_000098"
     CDS             complement(37117..39258)
                     /locus_tag="TV193_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512342.1"
                     /translation="MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTVFYT
                     KDKRIYDQKGSPYLIKGVDVESSIAGYRRRDLSVDEKTYYRWFKQIAAMGANTIRVRV
                     IMPVTFYHALRRYNDRASHPLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVD
                     VIHGRKRIWHSDLGLQHYDQDMSKWLLGYIVGDDWYSGTIAYTNHQNHAKPVGFKGRY
                     YATTPQANRFEAILAEIMEEITSYESRKYGWQHLVSFSNTPQSDPFVYQDPFASQAAK
                     YVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLTDRLVGDIKRMPLYQ
                     GYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGC
                     CGATIHSWQDDWTARSWNTSFATNKHQSFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQ
                     KAADEWSRALTYKKNGQQLLVDQDEKYLYIAIESTKKQPLQRQWLIPLDITPKTGSRV
                     IEGFSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTP
                     RFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGE
                     RLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVIAMVEY
                     PLLSWERPRVREVLKTSYQQVQAVWQEKRRR"
     gene            complement(39265..40698)
                     /locus_tag="TV193_000099"
     CDS             complement(39265..40698)
                     /locus_tag="TV193_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HEL1512343.1"
                     /translation="MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSR
                     STGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPR
                     LSLTALIAYRGNSSRHFDKKSLKLRFINKRAKPKAVSLAGMSKESEWVLHGPFLDRTL
                     VRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSD
                     KTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHI
                     EKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDF
                     NNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKY
                     IDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPASRNYSSYEASVKQLKDFIRR
                     RGRWLDKHIETLYQYSAPSKNTNTLLE"
     gene            complement(40704..41381)
                     /locus_tag="TV193_000100"
     CDS             complement(40704..41381)
                     /locus_tag="TV193_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HEL1512344.1"
                     /translation="MKQLLRHVFEQRGTLSFQDVLLHIVAAALLSIVIYMSYAYTHTG
                     TAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIF
                     WTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLV
                     FNYFSGKAIQSVKNTTSDDIEMIFELSRKDYDSTYQQANPLTEAVYQLGRVDYFNIVS
                     QSDDITG"
     gene            complement(41395..42090)
                     /locus_tag="TV193_000101"
     CDS             complement(41395..42090)
                     /locus_tag="TV193_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HEL1512345.1"
                     /translation="MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRS
                     LYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSNQKKRSLRLTRA
                     DAQLLIKGDKSILLTYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFD
                     HHIIGSETNADIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASK
                     YCMGRAISKHYRF"
     gene            complement(42218..42853)
                     /locus_tag="TV193_000102"
     CDS             complement(42218..42853)
                     /locus_tag="TV193_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HEL1512346.1"
                     /translation="MKYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQTDLAD
                     LRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIRA
                     PYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQ
                     QQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR"
     gene            complement(42843..43382)
                     /locus_tag="TV193_000103"
     CDS             complement(42843..43382)
                     /locus_tag="TV193_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEL1512347.1"
                     /translation="MVKGVLRGDKLLEFEDIYLEYKDDVYRFVNKLCCYQNSLSDDIT
                     QETFLKAYRNIAKFSGDSSIKTWLFTIAKNTFFTEIKKKKYENMSMESLEIVDAKGHD
                     EPLDKIARRELLEITLTIIFNLPEKMQAVFLARIYSGDSYEKIAKDIGITVSSAKVLV
                     FRARKHIKRQLREEYGYEV"
     gene            complement(43671..47387)
                     /locus_tag="TV193_000104"
     CDS             complement(43671..47387)
                     /locus_tag="TV193_000104"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEL1512348.1"
                     /translation="MMKRLGENQALFEERQLFGIRKLKLGVASVAIATAFSLGTASGQ
                     ITAAAESLTSVEPADGAVMVKSEAADQGSNELPEATDISDIAGISDVTKVSAAVNADT
                     VKEVQPVAVPLVEDQAHEETTDQSQPSSSIVSVTTDSSLETPEATSSEEPIAEQTLRL
                     HFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSANQ
                     ANKVSFLINNTKGDNLTGDRTIDLLSPKMNEVWIDGQELSYYRPLAQGYIRINYYRSD
                     GHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADTNELGFLLLDE
                     RQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNTVRLIGAQQVSPSSIE
                     ASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYTVT
                     FHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKADQ
                     TKVIGNLALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRNGKSVLVLDPYAKSL
                     AAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDFTS
                     DQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTYSS
                     SDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYNHT
                     ANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKVDG
                     FRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQTD
                     TVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVIQY
                     IAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEYGR
                     TKQFKDEAYKGKVADDKVPNKSHLLVNEDGTPFEYPYFIHDSYDSTDAINHFDWAKAT
                     DTERYPESTTSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDLVI
                     AYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEGVV
                     LTKDGVKLSGLTATIIRLRASQSDKGTLGAMTDQAAHHQEKLVAAQTAGEVSQFSAKT
                     LPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR"
     gene            47867..48412
                     /locus_tag="TV193_000105"
                     /pseudo
     CDS             47867..48412
                     /locus_tag="TV193_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            48493..48948
                     /locus_tag="TV193_000106"
     CDS             48493..48948
                     /locus_tag="TV193_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512349.1"
                     /translation="MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLW
                     DKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKE
                     DFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT"
     gene            48948..49235
                     /locus_tag="TV193_000107"
     CDS             48948..49235
                     /locus_tag="TV193_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512350.1"
                     /translation="MTTWYDYMVRASEHSGSDGDLWFRYLYKVIKDKETKLTTDDVEQ
                     LLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG"
     gene            49228..49776
                     /locus_tag="TV193_000108"
     CDS             49228..49776
                     /locus_tag="TV193_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEL1512351.1"
                     /translation="MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDIDA
                     FYQEGVNIRQMIKKVGDEFGVNEPDELWLNNSVANLNRIPPKTICETVFHYSNLIVLV
                     PPLSYILGMKLESGRDRDRQDAGDIIKLANIRSPKKLINTLEEYDFQPDISMILEVFE
                     IAYGMEWLANYMTEHPEEFRHY"
     gene            complement(49955..>50113)
                     /locus_tag="TV193_000109"
     CDS             complement(49955..>50113)
                     /locus_tag="TV193_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1512352.1"
                     /translation="EAQKGDKPAVPKAMEHKLPSTGEATAPFFTAAALAVLASLGVAV
                     VSRKRKKH"
BASE COUNT        14852 a        11479 c         9516 g        14266 t
ORIGIN      
        1 atgacattat ggctcctaaa taagttgttt tgcattttat tattttggtg atggatttga
       61 ttaaaactag aaatcatata tctccttata tgatcatcac ttgatggact gctcaactgt
      121 ctgatacaag attaagccct ttcttcttag ttaacagcta ccaaagaaag gtaaattggc
      181 tcctttatac taaattagag atagctaaaa acatctcaaa tactcttgac aaaacgtcat
      241 gactgtctta tctagctaga ttagctaaca taaggcatta aaaatagact tagaaggttt
      301 ctaagtctac agtcgatctc tattatttgc caagctttgc cttagcagca tcagcaaggg
      361 ctgtaaaagc tgctgcatca ttcaccgcta aatcagcaag cattttacgg ttaacttcga
      421 tttcagcaag ctttaggcca tgcatcaatt gtgaatatga caagccattc atacgagcag
      481 ctgcattgat acgtgtgatc catagcttac ggaagtcacg ttttttctga cgacggtcac
      541 gataagcata gtaataagaa ttcatgacct gctcttttgc agtacggaac aagatatgtt
      601 ttgctccata ataaccttta gctaatttca aaatacgttt acgacgtttg cgtgatacaa
      661 cgccaccttt aacacgtgcc attaatattc tccttcaaat aactcttata attctagtaa
      721 atacctgtta caacccttaa tcttaaaggc cagtaaccat tgctttaata cgcttgaaat
      781 ctcctgcatg caccatacct gctttacgaa gatgacggcg ttgcttttta gtctttccat
      841 ggaaacggtg tgatgtaaag gcacggaagc gtttcaaacc gcctgaacct gtacgtttaa
      901 aacgtttagc tgatgcgcgg tgtgtttttt gttttggcat tttaatattc tcctcttaac
      961 atatagtgta atatgacaat tacttcttgt ctgaaattgg tgcaagctgc ataaacattt
     1021 ggcgaccatc catttttgct ctttgctcaa taatagcaat atcttgagtt gcctcagcaa
     1081 aatcagccag taccttagca ccaatctcct tgtgagtaat catacgtcct ttaaaacgga
     1141 tagaaacctt aaccttattt cccttttcaa ggaacttacg accattacga agctttgttt
     1201 caaagtcacc cttgtcgata actgggctaa gacgtacttc ctttacagtt acaacgcttt
     1261 gctttttgcg ttgctccttt tgcttttttt gatactcaaa tttgaacttt ccatagtcca
     1321 taagcttggc aacaggagga acagcttgcg gctggattaa aaccaaatct acatttgcag
     1381 catcagctaa agactgagct tcagataatg gtttaatgcc taattgttca ccttcaagac
     1441 caacgagacg aacttcgcga acacgaatct catcattaat gaatagatct tttttagcta
     1501 tgatcttcac ctctttattt ttttagagaa aaacgaaagc ggacttaatg aaccaagccc
     1561 gcacacataa tatcccgtag gaatttgaca tgtagggcca gacaacctag gtcgcaaggc
     1621 gagaagctct cacttctgct tttctcatta ttgacattct aacaaataaa tcatgccatg
     1681 tcaattattt tttctgcttt ttcctgaata aattggacaa cagctgaaat cgtgataccg
     1741 gtagtatcaa agataatcgc gtcatctgcc gcctttagcg gcgaaacttg acgatgactg
     1801 tccttataat cgcgtgccgc aatctcagcc tttaaggtgt caaaatcagc tgcaatccct
     1861 ttttcaatat tttcctgata acgacgctgc gctctttctt caacagaagc aatcaaaaag
     1921 atcttcaact cggcatcagg cagcacaacc gttccgatat cacgaccgtc catgataata
     1981 gcaccagtcc tagcaattcg tcgctgctga ttcaccagct cctctctaat ctctggcaag
     2041 gcggacaccc aagaaacatt attggtgaca tcattttgcc tgatcgccat tgtcacatct
     2101 tggtctccaa gaaaaaccag ttgtgagcca tcagctgctt ttttaaaaga aattggacgc
     2161 tttgccaatt cttgcaggat tagattgaca tcttctttgt gataaccatt ttttaatgcg
     2221 atataagtcg ctgagcgata catggcacca gtatctaaat aggtgtagcc aagatttttg
     2281 gcaataatct tggctaccgt acttttccca cttgaggctg gtccatcaat cgcaattcta
     2341 attgctttca tcttttcctc tttaattatt tgatattgac ctcgtcacct ggattggcat
     2401 accagtagcc ttgggtcata tgatctgggt ttagggcctg taattgctca acagaaattc
     2461 cagcacgagc tgcaatagat gttgctcctt ctcctgctaa tactgtaatt gtctttcctg
     2521 ctgcctctgt agaaggtgct gtttcagtct tagaaggact tgttgtgtca ctagctgctg
     2581 agctattaga gctcgctttt ggctttgttt ttggttttga gctgaccttc tttgttgtct
     2641 ttttctgagt tgatgccccg taaaatcctg ttgtctcatt ttgcttgtta ctaccgctgt
     2701 ttgacgtata gaagaaaata aaaagtatgg caacaataat gacaaagaaa acacttaaca
     2761 aggcagtcaa ccaaggtgtg ctaatgagtg ctcctcttga ttttcttgtt cttgtcgcct
     2821 tattgtcatc aacaattttt tcttcccatg gttctttagc catgattctt cccccttgtt
     2881 aatttaacaa aatcatatta gaataatacc tatgaaagta tctatccttc cagaaaaatg
     2941 cattgcctgt ggtctttgcc agacctactc tgctcttttt gactatcatg atgatggtat
     3001 cgtcaaattg gctcagtctg atgagtcaag tcaactcata gatcctaatg atcatgatgc
     3061 catcttagca gtaaaatcct gccctactaa agcccttacc ctcgagtaag aggctttttt
     3121 tcgtattggt aggcttcaaa ataatccagt ttaatgaagt tatctagtaa tataacctct
     3181 cccttaaaat aaggattaat cgctagatca tctaaaaaat attttttagg ccattttctc
     3241 atgtaaaaaa ggtagctctt atcaccaaca aatagacaaa ccgttgattt agtaacctca
     3301 attttggtaa ttgaggcaat catcagtctg tgcggagcaa atagctttaa agatacgatc
     3361 ttcaagacac cattattctc aattacaaaa taacgatgca ggccaagtcc cactaatata
     3421 gcaaataaag caaacaagac aaaaacacga ctcggtattt ctgttctttc atacaataag
     3481 gacaggccaa taaaaatagg cgcaacagca attgaccaat aaataataga ccaagacagc
     3541 tctggctgcc aatgatacct tactttaccg aataatttaa tcatgctttt ccatcacctc
     3601 caatccgttc tgagcatttt gggtgatgtt aagccttttg gacaatgcca agaatcacat
     3661 caactgcctt ttccatcgtt tgcagactca caaattcaaa cctgccatgc atattttcac
     3721 cacctgcaaa aatatttggc gttggaatcc ccataaagga aatctttgag ccatcagtac
     3781 caccacgaat cggctcgata actggcttaa tagctaggtc ctccataaca gccttagcta
     3841 gattcacagg tgtcatgtcc ttttcaatca cctttttcat gttatagtac tgatccgtca
     3901 ctgttacaaa tacacgctct gctccaagct gactattcat ctcctcagct agctgtgtta
     3961 caaaggcctt tctagcttca aaggagctat cctcaaaatc acgaataata taagaggcct
     4021 gtgcttcttc tacagtacca gacatgctgt gtaggtggta aaagccttga tagccgtccg
     4081 ttttttcagg acgatcgtca actggtaatt gactatggaa atccattgct agctgcaggg
     4141 cattaatcat ctgattttta gctgtaccag ggtgaacatt gcgacctaac accttgagct
     4201 ctagggctgc tgcgctaaag gtttcatatt gtagctcgcc aagcggacct ccatcaatag
     4261 tataggcaaa gtcaacatca aaagcattaa catcaaactt atctgcacca acaccaattt
     4321 cttcatcagg tccaaaggca accttaatgt cgcaatgctc aatctgaggg ttggcaacaa
     4381 gaaactcaat agccgtcatg atttctgcaa ttccagattt atcgtcagct cctaaaaggg
     4441 ttgtgccatc agttgtaatc agggtctgtc ccaaatattg gttgagattt ggaaaatcct
     4501 ctgggcataa agaatagcct gactgaccaa gcttaatctc cccaccctgg tagctctcaa
     4561 taatctgagg ggctactcct tctgcattaa aatcagcagt atccatatgc gcaataaaac
     4621 caattttccg agtcaatttg ctgctgttag ctggtaagct tccaatgagg tagccattag
     4681 ctggattgta atgaatgtcc tgtaggccaa tagcttccat ctctggcttt agcactgtta
     4741 gagcaaagtc agcttgactc ttggtgcttg gagttgtagt gcttgctgga ttgctccttg
     4801 tgttgatttt tacatagttc agaaatcgtt ctaataaagt ttcgtatgtc atagatcacc
     4861 tcgataagtt ttcgttacta ttatagcata aaaggaccta aaatacttgc ctaagctcag
     4921 ttttttacag tgctttatct gttctgttac agttgcgttc tcataaaaag acagctgcca
     4981 agaaagctct tgacagcctt gattattcat cagcccatgc cttaatcctc ataaccattt
     5041 gggtgcttgc tttgccatct ccaagtatct gtacacatcc tttctaagcc gtactctgca
     5101 gtccagttaa gctctttttt agccttgcta gcatcagcat agcaggctgc gatgtctcct
     5161 tgacgccttg gtaatatctt gtaaggaata gacctgccaa ccacctgaga aaaggcttcg
     5221 ataatatcta gcacagaata gcctgtacct gttcctaaat tataaataga taggcttggc
     5281 tcttcagcaa actttgcaag cgcagcgacg tgtcctttag ccagatcaac aacatggata
     5341 taatctctaa cgccagtgcc gtccttggtc tcataatcat caccaaaaac gccaacacaa
     5401 tccagcttac caacagctac ctgagaaaca taaggtaata ggttgttagg tatgccctta
     5461 ggatcctctc ctaaatcacc agactcatga gctccgatag gattaaaata ccttaacaat
     5521 acaatatgcc actcattatc tgatgcatag aggtccttga aaatctcctc tagcatcagc
     5581 tttgtcctac cgtaaggatt ggtcactgat agtggaaagg tttctaaaat aggaacggta
     5641 tgcggatctc cataaaccgt tgctgaggag ctaaaaatga tctttttaca attaaaggct
     5701 gtcattacct ttagtagggt caatgtgcca gagatattat tgtcgtagta atcaagtgga
     5761 atcctgcttg actctccaac agcttttagc cctgcaaagt gaatgacact cacaatagga
     5821 tgcttactga aaatatctgt tagcagctgt tgatcgcgaa tatctccctg ataaaaggtc
     5881 acttctcttc cagctatcga ggcaacagca gctaggcttt taggatttga attgcacaaa
     5941 ttatcaacca caacaacgtc atagccagca gctagcagtt caacacaggt gtgtgacccg
     6001 atatagcctg caccaccagt aactaaaata cttcctaaca ttgattatat acctgacttt
     6061 ctaataatta ctaatattat aactgattac tcccaaaaag tatatctatc atttcatttt
     6121 aaagaaatca ggataggcat taatgtagcc cttgccttca ataagatcat attctaacag
     6181 ctttaagtca gaggccacct gcttttgagc agcagttagc tggctgtcat cgctatttct
     6241 ggtatccaag acatctgtca aaagagcgta gtaaggagac accttggaat ccgtatgctc
     6301 tagcaataaa gaggtaaaat cactggaatt aacacgaggt ctagccaatt tgttggtctg
     6361 atgattgctc cagatgaaat aatctgttaa atatttgacc tcctcatcat tcttaaagac
     6421 ctgatctgga taaaagccag gtaaatgatc accataaaac acaactgtaa taggcttgtc
     6481 aaccttttcc agtgctgata aaaaggcctt tgttgacttg tcggtaatgc ttaataaatt
     6541 cacataactt tgcaggctat ccgtctcaga ctggtccagt cctgctaggc taacatcaac
     6601 atctcttagc tctgtgtacc aagggccatg attttgcatg gtaatcactg aaaagaattg
     6661 acttcttttg gggttaagct ggtctaaaat attgtcatag gttgactcat cactatagct
     6721 tgagctcatt cgtatcaagt gctttggctt gtcagctgaa tcctctgtgg caatgaaggt
     6781 atcaaatccc aatttgttgt aaacgatttt tcgagagtaa ttgttggcgc tcgcaaggtg
     6841 caaaacaatc ctatccttag gcgaaaaggc attactaatg gcaggcgaaa acttcaactt
     6901 aggaaagaca tcagaataca aaatcgaaac tgttggattg aggttatatt ttggtaggcc
     6961 aaataggctt tgaaactcca tattagctgt accgccgcca tagccatcag aggtcattag
     7021 gccactcgtt gtggtttcca tgatatgatg gatctctgca ataggatcct tggccaattg
     7081 aaccccagaa atcctagctg ggtcagcaaa gctctcactc agtatataaa tcactgtttg
     7141 atcagaaata cgctgatgcc tttgcttatt gatatcagca gctctagctt gatatttctg
     7201 ataaatcttt tgcatagcgc tcttgctata gcctgaaggc tgattaatgg tgctggtggt
     7261 aacctgcttg aaccaaacaa agctcaagga ttgaaacctt gcattggttg taagaccata
     7321 ccagtcaata tcaaagacat tgtagactga tgacagaact ggaatacctt ttttgatttc
     7381 accatcttta ttttggctaa atacaaaaag gatagaggca aataccaaaa ggatagagcc
     7441 tattgacatc agtctaagat aaagcgctga taggatcttt tctctaaagt atcttttata
     7501 caaaacatag atcagcagac ccgacaagac tagtatcaaa ataatactaa tgatttgagt
     7561 cagactaatg taattcaaga aaaacttaat ctctttgatc catttcaaat ctgaaaacaa
     7621 taaaggctca cttcgctgct tgtatttttc aatattaaca atactgatta aagctccgat
     7681 caccgtattg acaaataaag caatgatata gttgttaatg agcaaaaaca ccagcacaaa
     7741 aaagagggtc aagacaagca cctgaaacag ggttgcacct ggaataatca ctgccccatg
     7801 aaaatcacca tatgctgtga tcccagcctg aataaagtaa ttaaagatga tccctaaaaa
     7861 taagctggtc actagagcta atctaagacc ccatcgcttg ctcaaaacct cgataaaggc
     7921 tgtgacgatg aggtaataaa ccacaaacgt cagcatataa gagcaaaagc tatacttaaa
     7981 gagattcagg ctaacaaggt ttgactgact atctaaaggc caataatcat tttgcttaat
     8041 cacagtctta aataaagagc tgttcagcgt taagactgaa aaagcctgac taagtaaaat
     8101 gacttggatt cctctgtttg attggtagtc cttcttaaac aggtattttt ttaagagaac
     8161 ccctaaaata agcaggctga ctaaagctgc cagactgagt agcatttcct gaatcgtacg
     8221 attactgatg gtaaacctgc tgttgttttt attgatggct aaggtgatat agctattagc
     8281 aacagcatag tagctactga cagctacaga aacaataagc agctttgagg aagcatgctt
     8341 gatcagcaaa catgccattc cagctattaa cactaagaca agccacgaac cataagctcc
     8401 cttatttaac gtgtttttgc ttaccgcaaa aatagataaa taaagagatg aaaggctaaa
     8461 caatatcata tcaagcattt ctagatcaac taactggcga gcttttgaaa ttatcttcgt
     8521 tattataatg gtcacaccct ttcctaactg ctaaaagcta gacattactc tctgactcag
     8581 aagcgattac ctctgttact aattgacgaa cagtgacctc ccaggtaaag cctgaaagca
     8641 cctgctgatg aatggcttct tgcaggtcac accgtttttc tttgtgctca atcaaatgat
     8701 ccaactgcct tttaatatca gagactgtat catcaatgat gattccctgt gacgggctcg
     8761 ttatcacttc cttgacacca cctctatctg ttgctaatac agcacatttc aacatacctg
     8821 cctctaatac agctgtcgga agcccttcag catagatgga cggattaaca aaaatatcag
     8881 attgagacag caaagacatg gtctcagcaa aattcagctt gcctgtaaag atgatggact
     8941 gatcctcttt atagctatct cttagtgaag caagcaaggg accatctcca gcaaccacca
     9001 agacagccct gtccttatat gtcagctgct caaaagcctc cagcagcaaa agaatcccct
     9061 tttccttgat cactcgacct gcaaaggtaa taatgacctt atcctgcaaa gctggtaaat
     9121 aagcctttga cttaaagacc tcataaagat cagaatcaac tgaattgtag atgacgcctt
     9181 tggcttttat tccaaaggtc ttgagccatg ccatactgcg cttagacacc gcataaaagt
     9241 cgggctgata ggctttgaca aaaaaggtaa ttacatgctc atagacttta gcaaacaagt
     9301 ctagtagctg gtgaccttta acattttcgc ccacctgaac atagccacca ccatgctcga
     9361 tcacaatact agggatggct tttcttttgg ctagcttcaa gcccatgagg cttgtcaaat
     9421 aaaatcgtgt attgcagatc acaaagtcaa tacgttcttc catcagctcc gccagcatgc
     9481 tatgatacag atcattctta tctaaaatcg gatagcgctg cttaaatagc tgctttgaag
     9541 gaaatcggta ataagtaatg gcttgatctc tttcaatagg gctcagctgg tggctgttgc
     9601 tggttacaat gatgatacgg tagcctaggc tcactaattg ttgcgctatt ttttctgtat
     9661 accgctctac tcctcctaga tgagggcttg taaagccgct aaaaatggct attgttttca
     9721 aagcttttcc cttcttatgt ataatattgc agcattgttc gagtaatcat acctaggatc
     9781 aatagcaacg agccaataag aacctgttta ttacttaata ggccttgggc cttttcaagg
     9841 tatttgttat tagaggccag caagaccaac actaaaggga tcacacccaa aaagtaccta
     9901 tcttgaaccc ctagcacatt aaggtctcca actggcgtaa aggtcaaata aaggctaaag
     9961 gtaataccgc ctattattcc taaagacatc aatcccatac caaagcgaga taaggtcggc
    10021 agctgaagct tgttggcatt agtgatgaca acagcaaaat aataaaccat actaattggc
    10081 atgagctcta ccataccgta tgataaaggg ccaaacatgt aaatccctga aggattaagg
    10141 atatgagcca acgtgtgtct tagcagcata aagccatata ctatagggtt ccttaacaca
    10201 gtcagtagct gctctttagc attgaccttc tggagaaagt cagccatatc cacctgaggt
    10261 gacttgattt gaccatatac ctttaaccaa aaaacagtca caaccagcac cgtcagaatt
    10321 gacaacagct ttagcagaaa cgtgcgagag gcttttgctc caaattgacg tgaagggata
    10381 aaaagcagca acaaaatcaa taaaatataa ggcagcttag taaaggtaat gattgagcac
    10441 agcagggtat accaaaagag cttggataag ggaatctttt cagttgtagc catctgaaca
    10501 aataaagaaa tcgtcagaat aatcaatcca atagagacac aatcctgatt ataagaacca
    10561 gcaagataga tattcatcgg aaggagactt cctacagcaa gcagctgctt gcctgctgtc
    10621 agcaatcgta aggcaacaaa aaccaagatg gcataggcaa gaacattaca aagcctacct
    10681 aaaaggtaag ataagcccat ggtcaagcct aagctccttc caataaataa gcctattacc
    10741 tgtggtatgt aggcaaagtt ataatagcca tttgttgagc gaatttcctt aaatgaaata
    10801 gcctcatctg tatggtctct gctccacagc tgaaagcgta agggcttgcc attgttgtgg
    10861 tccataagat taatgtcatc agtcaccagc agctttgagt catcattggt taaattaaga
    10921 tttccctcag ataagtataa ggctcttgca aagtgaaccc tctcatcagg aatatcattg
    10981 atcggtgaga tgaaggcaga gacagaaccc ataaccacaa taataagcac tgtcgcatat
    11041 tccatatttg aaggtaaaaa gataatcaaa agcgcagcaa ttgcaactaa tattgctaaa
    11101 aatttaatgg gtaaatccgt tgattgcgta tataaaagca gcaacacaag aaaggcacca
    11161 agtaaaacaa gcaaagcctt actcgccttt tgcaatttgt caaataaggt atctaacata
    11221 tcctatttcc ttttttccat aatgtacaag ccatatgaca atagcagcca aatcatcatt
    11281 gaaattataa aaccataggt aactccaatc accccaaagc ttctagccaa agaaccagtg
    11341 atggctagtg aggagataaa ggatacaaca taaggtatca caagcaagtg ctgctttctg
    11401 ataatggtaa tcaaattatc aatataagtg gcaaaggtgc tgataatccc tccaaaaata
    11461 agaagcataa aatcaagctg gtaatgcctt aaatcaatac cataaacaag cgatagcacc
    11521 ggcagcccca caaaatagct agcaagcaag atagctaggc ttgctaatag cagcactaga
    11581 ctgagacgac gctctaattg tgcaaagctc ttctcgtcct cttttgaatg gtaaatggcc
    11641 agctgagtga tcataggcct taaaaacaag aaaatcaggt taatcataaa aataggcata
    11701 aacaaaatat taaattctgt ttgaacaccg gctgggatca gctgctttga gtaaagctgc
    11761 tccaaaacaa acttgggctg gttgtagata taaatgagta aaaaaccatt taaaaagagg
    11821 ggaaagctct ccttcaatag ccctaagatg ctttgagcat caatacgacg ctcaaggctc
    11881 gtaaaggaaa ctgaaggggt tatgtcaaat agcacaatac aagccactga aataagacat
    11941 atcacgatca aagacaggac tagctgcttg gtcagaacca gacagagcgt aaagccaaga
    12001 atcaccagca tatttcgata aaacaaggat ttgccggcaa tatctaagcg ctctctttgt
    12061 tgaaacattc cttgaaacac atcagaaatg gcatctgtgc aacgatacaa gcaaatcaac
    12121 caaatcacta gccccttaaa cccactatag ctccccaaat aaatatagag cactgaaatg
    12181 gctatcatca agaaacaggt gactagtctt gtataaaaat agtctttgaa gcggtacttg
    12241 tgtaatatat ccgttgattg gaaatttcta atctgaaata agccaatagt aatcagctga
    12301 tttccaatag cataggcaaa gctaaaggta tctgaagctg atttagataa gacccgagac
    12361 acaatcatca gtaaaatcac tgatattagt gctgtcgagc tggttcccaa cacattccaa
    12421 ataaaaatcg actgatccga ttgaatccta ctgctggttt tcatcttctt cctgcttttc
    12481 cttctcatta agggctaaat actgaatcat ttttttaagc ttaatctctg tccgagacaa
    12541 tttttgagtg ataaaaaatt ggttgatgat gagtaaaaaa atgattgata gaaaaacaaa
    12601 atttgccggc gattcaaagc ctagcagcct tgaaaaataa accgcagcat ttggaaacag
    12661 tgacagcaaa agcactatta aagagaaaaa gagccaaaaa aagctatctt caattaaaat
    12721 tttggatctg cgaatgctat ctagtataaa catggctgtc aataatgcaa caatgatcaa
    12781 aatcagctgt aacccaataa acatcctctt acctctttct aaagttttga attaaaataa
    12841 tcgaaataaa catgtgaacc atgtatttaa tagatctaga aagagtgagg tagctttgac
    12901 cagccagcct atcattcatt tgcacctgaa cctcactcac cctatagcct tgtcgaataa
    12961 gataagagat cgtatcaggc tctggagtat agttaatatt agttgcaaaa atcctgatca
    13021 gctcctgatt aaacattctc ataccagagg tcggatcggt aatacgcttt cctgtggtta
    13081 gcttgataaa aaagctaata aggctattgc ctatcattct caaggatcta ttcttttcag
    13141 cactgacaaa ccttgatcca atgacacaat cagcaccagc attaattgaa tcgctcaaag
    13201 cctcaatata ctctggcaag tgttgaccat ctgcatcgaa ctggagtgct ttagcatatc
    13261 cctttttaaa ggcatattta aagcccgtct gaatagcacc agataagcca agattttccg
    13321 gcaaatcaat gatattgtaa tggttatgat gacagatctc tgatgtccga tccgaagagc
    13381 catcattgat aatcacataa tcatattgag gaaaatgtct tttgatattt tccactactt
    13441 tttcaatcga ctcctcttcg ttatatgctg gaatcattac caataagtct tttttcatat
    13501 cgtcaaatat tctctctatt cattcgtcta aacgcgtctt tttagcaatc gctttatgat
    13561 ataacggata gccttagctg gcccaatcac aatatatttt aaggctcctt ttatacctcc
    13621 catatagtca aaatcgacat aggtatgtgg cacactgcct tcacgcaggt ttaagagctt
    13681 attatcaata aatggtgtca atagcttttc atttcttgaa attctaaaat catagtgtct
    13741 gtcccaagca atataaatta agagacgttc aatggcatgc aggatcgaat tttgagacag
    13801 aggctctgct ggaatatcag cctcacttag gtctaagtca aacaagggct ttaaggcatc
    13861 gtatttaaac caaacaaagg tgccatagct catgacaaag gtatccatcg tctgaaaatc
    13921 aatgcgtttt gtaagcccca ttgcctgcca aagctgattc atttcagggg caataaggtg
    13981 ctcattccaa gcgtcaacaa ttttattaaa acggaaaaaa cttggaatat ctgctatcac
    14041 aataccgata gcatcagcag ccagtgctgt taggatttga tccgccggct tcaccatcat
    14101 atcaatcaat tcagtgcgcc aggattggcc cgcccaaaaa tctgcttcct ttgatttttt
    14161 ggtatgaaaa tgcccaatat aatcatattg agacaatcgt tcctttaagg tcagcattgg
    14221 caagacatct cgaccgatat ttcctgtcac caatatgtca gcacttgccc cgctttctcg
    14281 tagaatttct ttaatctcag cctttttagc cttgctatcg gtcgttatga gcaagtcata
    14341 atcaaaatga aaatgactaa atgcttctaa aaactctgac aataaatcaa cataaaaaac
    14401 atgaagatga acagcaattt tcttgctttg atcaatgctt atcggctgct ctggcaggta
    14461 tttatgtgcc agaagatact tagcatctgg tggatggacc tgcgacatat gatccacaat
    14521 caagctggca gggtatgtcg ttttttggtc aataaaatcc aaaaggtaag gagcaatgtg
    14581 ctggttagcg tcaatagcct taaccttgat aaagggcaca tggtgcttta agatggctgt
    14641 cggattgtaa taagagaaat ccgcatgcag catagaggac gagtcctcct tggtcgtatc
    14701 aaataccgtc ttgtatcgaa agccagcctc cacaaagaca gtggttattc tggtttcata
    14761 attgtggatc acatcttgaa cgtctgttag ctcaacgata ttttcccaaa actgcctaaa
    14821 ttccttacta tgaacgaggg attttttgaa gctgataaaa tagctctgaa tatgctcttt
    14881 aaaggccttg gtcgctcgat tgttggtcat gccccagaaa tcaactgctt catctgcttc
    14941 atatttgaga taataaggct tcatatccca aagcggacca aagcaggtat cgttcataat
    15001 cgtgattgag tcaaagtcaa caaggtgctc acagcctaag gccttcatac catcatgcca
    15061 agctgcaaaa tcatagcctt tattgtgtcg ttgaataaac tgatccatca aatgccgctg
    15121 ttcaagctgc tcaaggtcct cttgatggat atcactattt gaaataaaga caatctttga
    15181 aaacaaggct ctcatctgtt cgagctggta ataaacatga tcgcttacct tatgatattt
    15241 attgaaatgc acatacaata atagacgctt cattttttcc tcctaaaaag ctcaagcagc
    15301 tttgataggt acctccaacg acgtgaggta accacacaat tgtattgatg ggttagcgct
    15361 tcaacctctt gcctttgatg atcaagctgc tgctgtagct gatctatctt ctctgcctgt
    15421 agagcctcct gatctgcaag cgtctgtcgt aattgatgaa tggtatgact taattgatga
    15481 atccgaattt catttttagc gtcctgcttt agtaatgctt ttgcaatagc ttccatattg
    15541 gctgtagggt atttagacaa ataggacagc tgggtctcca acaagccttg aatacggccc
    15601 agcatttttt cctctgctgc cggccttgaa tctgaattat ccgtcattcg ataaacagtg
    15661 gtcgaatcct tcaaataggc tagagaggtt gactgaaaca gctctaattg tatgtcaaaa
    15721 gtgtcgtctg acgtctccaa atcaatgcgt tgattaactg ccctcatcag atcagcctcc
    15781 accagccagg ttgatgacat ggtcattcct tttaaagcaa gcattttctc gtaggtgtct
    15841 gttaagggag taaagccact ttcaaaggca ttgctctgaa taagcttgcc gtcagtatct
    15901 acaaaatcaa agtcagtatt agaccatttt gaatctggtg agctatccag caaatcaacc
    15961 tgcttttgta gcttgagagt atcagtccaa tagtcatcac catcacatct ggcaatatac
    16021 tgtccctttg cctccaaaca agccttgacc caggttcttg caatcccaag atttacctca
    16081 ttaacgatga gtcgtatacg atctggaaag ctggcttgat agtccatgag gatctgtctg
    16141 gaatagtctg ttgaagcgtc gtcaatgaca ataatttcaa catcaaagct ggtctgttgg
    16201 gctaaaaagc tgtctaaggc ctctgaaatc caaggcccct tattataatt ggtgcaaata
    16261 atagaaactt ttttcatagg atgctttcta atgacaatta ttgattaatg agccagctac
    16321 catttctttg atataagcca ctggcagagt ccaaagcaga caggtcatct ggagcaatat
    16381 cgtttcgttg aagcacgact aatggggaat gattagctgt taaaaagagc agcatttgcc
    16441 cgttttgatc gcgaacagtc acctcaagct ttaatttgat atcatttagg tgtgagagct
    16501 gacactggta ggatatgttc ttatgaccag gaccacttgt cggttgatcc tgtgaattgt
    16561 cattatatac ccaaatattg cggtcaatat cagtcaacga aaaggcaaca taggtaggct
    16621 cgtcctttaa gacatgatag gaaatctcaa aggaaatggg ctcatctgga ctaaggcttg
    16681 gcttagaggt caacctcacc tctaactggc ttgccaaatc agacacaggc tcagcagcag
    16741 ctccttgctc agcatttttc aattcagtat tatcaacact gtattggtta gcgacatcaa
    16801 agggttcgcc gtaagccttg acaaggccat tttcgatgag gactgcgcga ttgcagtatt
    16861 ttttgacagc ccccatatca tgggtcacta gtatagtagt cttgccgctc tccttgcgct
    16921 ccatgaagta gtcattgcat tttcgttgaa aggcctcatc accaacagct aacacctcat
    16981 caagaatcag cacatctccc tgtgccttga tagcgacaga aaaagcaaga cgaacctgca
    17041 tgcctgagga ataatttttt aatttttgat tcatgaaatc atgcagctca gcaaagtcaa
    17101 cgatatcatc atacatatca tcaacctctt ctgtggtaaa gcccagcatt gcgccattca
    17161 tgtagacatt ttcacgccca gtcaactcag gattaaagcc aacaccaagc tcgatgaagg
    17221 acaccatttt cccctcaact gtgacctgtc ctttttctgg aacataaatt tgagaaataa
    17281 tttttaataa ggttgatttt ccagagccat ttcgtccaac gatgccaaaa aaatccccct
    17341 tatacacgtc aaagctaata tcccttagca catgctgctc ggtatagccc ttaatgcctt
    17401 taaaacggtt aacaagagca gtacgaaagc tcttggttgc ctctgttggc agcttaaagg
    17461 acttactgac atgatcaact gttactgcaa tttctttatt agccattaga taatctccgc
    17521 aaacttctta gcatttttat taaacactgc taccccaagt gctaatagga caaatggaat
    17581 gaggtaagga atgatgatat agcaccaatt tgtcgacatt tgccaaatgg tcacattagc
    17641 tctgtcaatc agcagatacc gcaaatcttg aataatctgt gctaaaggat taagcatcaa
    17701 aatcttggca gcaagagggt gtcggtcaaa cacaaaggta atcgggtaga tgatgggagt
    17761 cacatacata cctgcctgca atagaacctc ccaaacctga gccaaatcac gataataaac
    17821 aaagacggta gaaagcatca aggccacacc aactgtaaga acagccagct caacaaagag
    17881 tggtaaggcc agataagcgt gaggagataa agtaactcca ttgatagctg caaaaaccaa
    17941 aaccactaat aggttgattg aaaagttaat caatgctcct aaaactgctg aaaaaacgat
    18001 agtatgcttt gaaaaattca attttctaag caggtctcct cgcgatacaa tagagaccat
    18061 tcccatactg gttgcttctg agaaaaagga ccaaatcaca ttggcaagta aaagagcaac
    18121 cggaaaatga ggaacgtcac caccagttcg caaaaacctg ataaacacca aatacatgat
    18181 ggtaaacatc atcaaaggct ttaagataga ccacaaataa ccaatagcac tgccctgata
    18241 ccttagttta aagtctgttt taacaagctc tttcaaaaga atacgattct ttttactcaa
    18301 taattccatt attcttttct cctatagcca aatttggtca tgatcaatgc cataaaaaca
    18361 agggtatgaa aggcacgatt tttccgaaag ccatacgctt tgaaatcaga cagacgctga
    18421 tagaaaggcc tatccaaaag ccctacgtaa gcctcaatca atcttctgtc agccggattt
    18481 agctgcaagt ctagcaattg ccttgcttga tgttgactag aaacaataag ccaccaatac
    18541 ttctctatga gcttatgggg cttacgccac tgcttcagtc gcttagacca ggttcttgcc
    18601 cctaaaacat tagcatcatg ctgacgatag agctctgttg ccacatctag atacacaagc
    18661 tctccctgcg ctgctgcaat caaggctaaa taccaatcat gcatcaccac atgctcacag
    18721 ctcacccact gctctgccag cgcgtgatta atcatcatag tgccgcctgt gactgtgttt
    18781 tcagtcaact cctggactag ctgagtatta gcatgatgtg attgtgtttg gatcatactc
    18841 tcatgacgta cttctaagtc ttgattgacc acctttaggt ctgtgtagac tagtaagggc
    18901 tcgcttatct tgtgcttttg cgcttctgcc agagtaagct ctaatttatt gtctaaccac
    18961 acatcgtctt ggtcactgaa aaaataaata tctgcctttt catatgttaa aagggtgtga
    19021 aagcttcgaa tcacaccgag gttttcctgc acatcagcat taatcaagca aattctcgga
    19081 tcctttttag caaaagcctg aatgatggca agcgttttat cagtagagcc atcatctctg
    19141 actaataagg tccaatcctg caccgtctgc ctttgaatgc tttgtatttg ctctgctaaa
    19201 aaccgcgccc cgttgtaggt agacattaaa atattaatct tcatctaaaa ataaggcctc
    19261 atactctcct acaattttct cccaggtata ttctttggca atgatttgct tagctctttc
    19321 tcccaaatca gcaaacgatt ccttttgatc aaccctgtta atcagtccag taaggctgcc
    19381 cttttctttt gtccaataaa gggctgctgt tttagcaact gattgattaa aggtcactcc
    19441 caaaaccaaa ttaagctggg tatgggctag ggcctccaaa agacctggat tggtacctcc
    19501 aacctcatgc ccatgaatat aagcaaaagc atgctcacga atataagcta aaagctgctt
    19561 atcatactgt gttccaacaa attttacacg cgcgtcctta tcacagccag ttgcactaac
    19621 cagccgctca aaataaggat ttttgtcatg gttgcaaata ataaccaaat cccgctgagt
    19681 agatgatgcc ataaactctc taatggctgt ttcatagttg ttttcaggaa caaagcgccc
    19741 caaaatcaaa tagtattggt tttctgttat ctcaaatgtt tgaaagtaag ttctgacttt
    19801 ttcatctgat gtagacaaac aagaccgccc tatttctgtc ccataggcaa taaaagtcgt
    19861 ttttgcccaa ggataagact ttttgatgta ggcttcaatg ccaatattat ctgagatgac
    19921 caaatcagca tgctttgtca tttgcttttc ggcgtatttc aggtattgct gaacaggctt
    19981 agaccatttt gaacgcttcc attccagccc atcaggatta atcaacaaac gcccaccacg
    20041 ctggtgaatc tgctttgcaa agggggcaat aaagcctcca atggtattgc ctagaacata
    20101 aaaaataggc ttttgaatat gatacctatc aatataagct aaagcgtgac taatagccat
    20161 catatcataa gcaatcactc tagctggacc gagcttagga ggattgatat aaaaacaatc
    20221 tgctcccttg tacacaaaat gctccttgtg cttgctatcg ctcaagcagg caatatgata
    20281 ggtaatgctt ttgttggtct gattagtgac taattcttca acaaaggtct caaaaccacc
    20341 atacttcgct ggtaaaccgc gacttccgat gatgaaaaca tcctgcatag cacactgccc
    20401 cattctaaaa tataattagt agtattatac catataaaca ggtcttatgc gacataaaat
    20461 ccatgaaaag agagccaatc tcctagatca gctctttagt gctatcgctt attcattgct
    20521 gttgcttgta aaaagcctcc agggcttctt gccaggtagg aatcacaaaa ccagttgcct
    20581 tagccttatc aagattcatg gttgagttaa agggtctttt ggctttagca ggaaaagccg
    20641 atgaatccac aggcacaacc tcgacagctg tctcttttaa gatttctcta gcaaaatcat
    20701 accaagtggt gtcttcttta gcatcatttg acaaatgata atagccataa ggcttgcgat
    20761 tgtctgctag atgacacata aactcagcca aggtcctcgt ccaggttgga cgcccatgct
    20821 gatcattgac gactgtcaag cgagagtggg tcttagcaag gttttgcatg gtaaacacaa
    20881 aattcttgcc ataatgacca aacacccatg cggtacgaat aatgtaaaat tgcttggtat
    20941 atcgctcaac agccagctca cctaagcgct tagcacgacc gtatgctgtt tgaggatcag
    21001 gagtatctgt ttctagccat tcctgaccag ctggcttttg accatcaaaa acgtaatccg
    21061 ttgaaatata aaccaaggtc gccccgtagc gctcacaagc cttggcaata tgctcagtac
    21121 cagctacatt gatagcttca ttcagtgctt ttccttcttc ttcagcagca tcaactgctg
    21181 tgtaggctgc acagtgatac actaagctag gcttgacctg agcaaaaacc tcctctactt
    21241 tagtcgcgtt ggtaatatcc atttcagcaa catcaacagc aacataatcg acgcttcgtt
    21301 cgtctaaaag ataacgaagc tctgttccta attgaccatt acttcctgta attaaaatca
    21361 tcttttctcc tttgtaaagg tcttatttct ttgagctaat cacgcagctc actcccatct
    21421 aatcctaaga gaggcttttt tgatcagctg accctagcaa gacctttgtt gtggtatcgt
    21481 atcagccttg ctttttatct agctaccgaa tacctagggc aattctcgca tagcggctca
    21541 tcttttcaac gctccaaaca gggtaccaga ccaactttac ctcaaccttg gtcacctctg
    21601 gaacatctct catcgcatca tgaatatgat cagtcaacaa atccgccaaa ggacagccca
    21661 ttgtggtcaa ggtcatgtca atctcggtat gaccattgtc atcaaaacga atctcataga
    21721 ccaagcctag attcacaata tcaataccta gctccggatc aataaccgtt cccaaagctt
    21781 caagaatccg atccttgata gctgcaacct gctcttctgt gtattttaat gtttcagtca
    21841 tagctattcc tttcactttt ttcgaagacc tgatatgatg ccaagtcaaa aaccagccca
    21901 aagaccagcg cattcagcat acctatgatg ccctaagctg actaacattg atagcctctt
    21961 tttagtcacc cttacattaa cactagtctt tagctactgg ctagcaaagg taatctcata
    22021 aaccagtaac taggcttgga gtcgttgacc ataggccact caccgtcaag gagagataac
    22081 gcatttcggg ctcgtctcct atttttagct cgccgttaaa aaggtccacc ggaccttttt
    22141 aatcctcaat gaagtctctg agctgcttgc tgcggcttgg gtggcggagc ttacgcaaag
    22201 ccttagcctc aatttgacga atccgttcac gagtgacatt gaagaccttc ccaacgtcct
    22261 ctaatgtacg cattttccca tcatcaagcc caaagcgcag gcgaagaaca ttttcctcac
    22321 gatctgtcag cgtatcaagc acttcgtcta attgctcacg aagaaccaca cgagttgtgt
    22381 aatcaacagg attttcaatc acttcatctt caataaaatc acctaaatga ctgtcatcct
    22441 cttcaccgat tggtgtttca agagacactg gctcctgagc gattttcaga atttcacgca
    22501 ccttatcagg ggtcatctcc atacgctctg cgatctgctc tggagtagga tcctgcccca
    22561 attcttgaag gaggttgcgc tgctcacgca ctagtttatt aatggtttcc accatatgca
    22621 caggaatccg aatggtacgt gcctgatctg caatagcacg agtaatggcc tgacgaatcc
    22681 accaggtcgc ataggtcgaa aacttgaagc ccttagaata atcaaacttg tcaacagcct
    22741 tcattaagcc catgttacct tcttgaatca aatcaagaaa ttgcatgcca cgccctacat
    22801 aacgctttgc aatcgacacc accaaacgca gattggcctc agcaagacgc tgcttagcct
    22861 ccatatcacc agcggctact gcaaccgcta aaaccttttc ctcatcactt gtcagcagcg
    22921 gcaccacacc gatctccttg agatacatgc gcacaggatc gttgaccttg gctgaattac
    22981 ttccgataag ctcctcgtct gtcagctcct ctggcttagg ctcttcaacg acgtatttag
    23041 atgagggatt tccttcctta tctgtaatgg aaatgccacc atctgtcaaa cgctcaagca
    23101 aatcatcaat ttggtcagca tctaaggtaa atggaatcac gagtttttct gtgacctcat
    23161 catcagtagc tgttccttcc tttttatgat gacgaataaa ctccgcaatt tgaacgttaa
    23221 aggttgtaat ttctttttct tttgccatat tttcctctat tccatttttc ttttttcagc
    23281 aatgaaacgc tctaaagcct ctagagccat ctggtggtca cccttactgc tagattccct
    23341 aatctgcttt ccttgcctat gcagctctct ttgctttagc aatgtcattt gccttgataa
    23401 aatatcctca atctcaccgc tagctatctc atcaggaaga ttttcctcta aaacccggta
    23461 ataggcttgg ttaacctctt cagacagttg cgataggtca taggaggtaa tctgccctgt
    23521 ggcctttagc tgctcataca gcgtctgaag ggctggtgta tcaaaataaa aatccggccg
    23581 atgacgaaat tcattgagca aatagtcgtg atgaagcagg cgatgcagga ggtgactttc
    23641 tgttttagcc aaggctgtca tgcttttgtt aatcggtaag gtcaccagag atgcctttgg
    23701 ttgactagcc tgtccttgtt gtaagctttg cctatcttgt agccttaaag catttaccga
    23761 ttgctccacc tgaaaataat caaaatccgg cagcaaatca gccaccttat taatatacga
    23821 attttgtgcg gtgattgagg gtgcttgagc aataatctgt gatatatgct ccacataagc
    23881 aatctgcgat tgcaggttat ccatattttc aggcttcagg tgatcaatca aaaactcaac
    23941 actgctaatg cgcgagtgct ggagcaattc tgctagagcc tctggtgaat gctgctgaac
    24001 aaattcatcg ggatccattc tatttggtat tttcacgatc tccacttgaa aatctgccag
    24061 cagctcaaga gacttggcaa tagcattttg cccggcgtcg tcaccatcat aagtcaatac
    24121 aaccttttgt gtcagctgct tgaggtgcct aacatgctct ggcgtcaagg ctgtccccat
    24181 agaggcaaca gtattaccat agcctgcccg gtaggctgca ataacgtcca taaagccttc
    24241 catcaaaaag acctcatgag tcttagcgat tatcggcttg gccttatcaa ggtggtaaag
    24301 ctcataggac ttgttaaata ggaccgtagc ccttgaattt ttatacttgg cctgctgctt
    24361 ttctatatcc tctcttgccc agatacgtcc tgaaaaagca atcatattgc ccttatcatc
    24421 acataaggga aacatgattc gatgacgaaa ggcatcataa atagcatttg attgttcaga
    24481 aacatgaaac aagcctgagg ctgttaattg cgcctcagta tacttttttg acaaggcttg
    24541 ataaaggtag tccatctcgt taggcgccaa gccaatccga aaatactcta ttagctgatc
    24601 atcaagccct ctttgataaa gatactcctt ggctctttgg ccaatctttg tcgtcatcaa
    24661 aaccgcatgg taaaacttag cagcatcttc atgaagatca attaaagcct gatgagggtg
    24721 ctgcttttga ctcaaactag tctgacttgg agcaacagta actgccatac cagccttatc
    24781 agccacaatc tgaacacttt ctaaaaaagg aacctgccga tattcctcaa taaacttaaa
    24841 aacatccccc gacttaccgc agccaaagca gtgaaagaac tgtctatctt cgatgacatt
    24901 aaaagagggt gttttttctt tatgaaaggg acacaatcca aggtagtgcc gaccagcccg
    24961 cgatagatgg acaacttctc caataacatc aacaatattg acattatgct tgatctgaga
    25021 aatcatctct ttgtcaatag ccaaaccgtc acctccccac aaaaagccca ttgtaaattt
    25081 acatttcatt ataccattga aaatgagctt tgtaaattgt aaaagcacaa tccttcatca
    25141 tctaaagccc gctacatcaa gcaataagct atgctaaagt attgacgtct cttatgatca
    25201 ctagcttgac tagcagtaca gcattaagta gctcatcagt ccttgataag ctcttctatt
    25261 agcctttttg acctatttgt gctatgataa gattatctga aaaaagggga gtcaatcatg
    25321 ctcaaagaat taaaagcatt tttatttaga gggaatatta tcgacctagc agttgcggtg
    25381 attgttggga gcgcctttag cgctattgtc acatcatttg tcaacgacat tatcacaccg
    25441 ctgatcctaa acccagcctt gaaagctgca aatgtggaaa acattgctca gctcgcctgg
    25501 aatggcatca aatatggcag ctttctcagt gctattatca actttttaat tgttggtacc
    25561 agccttttct ttgtggttaa ggtcgctcaa aaagcaatgc ctaaaaaggg agaggaagag
    25621 cccgctaagc ccaaaacacc aactcaggaa gaattattac ttgacatacg tgatttgtta
    25681 gccaaaaaat aactcaaagc tcttacagca gctggacctg tccggctgct ttttgatata
    25741 caagcacaga gcacttagcg atcaaaagat aatagaaccg gctctatttg ctgttttagc
    25801 atatcattgc tatttttatc agcagcaagc taaggtaaaa aaagacaaac tagtatcctc
    25861 atactggttt gccttcaaac taaggcagcc tacaaagggc cgcctttttt atgatgatta
    25921 gaatttttta cgtttgcgag ctgcttctga tttgcgttta cgctttacag aaggtttttc
    25981 gtagaattca cgcttgcgtg attcttgaag agtaccagct ttagtaacag aacgtttgaa
    26041 acgacgaaga gcatcatcaa gcgattcatt cttacgtact actgtttttg acatatgttt
    26101 cacctcctca agatattgta acattttcac gttctagctt atcttacatg atttttcgga
    26161 aaaagtcaat gatcttttct tgattttgag gtcattctta aaaaaatacc ttaaaatttg
    26221 ctgctgcatt aggcatcact tggcaaggct attctactgc atttcctgtt aataatgctg
    26281 cttcttgaat aaaggccttg tatttgccat ccttgtttaa ttgcttgatc accttattaa
    26341 tggtttgcct taggtcatca ctcccctttg gcatagctac agccttagca tctccatcac
    26401 ttgcctgcaa tttaaatggt gctaaagcca ggtctttatg ttgagctaaa aagcctgcag
    26461 ctactggtgc ttccaaatca acagcctgca cctgcccaga tttcaactca ttaatagcct
    26521 cacccatcac agttagagaa acacagttgg ctttattaag ctgctccttg actaggccct
    26581 cctcgatgct gcctttttga acagccacct ttttgccaac taagctatcc ttattagcat
    26641 aatgcttggc atctgacgct ttcaccaaaa tagcattttc agtttcatag taagcctcag
    26701 aaaaatcata cactttggca cgctctttgg tgtaggacaa accagaaatc gctatatcca
    26761 ccttaccagt ttgcagactg gataagacat tatcaaaatt catagcagag agttcaagct
    26821 taacccctag ttcatcagca atggcctgtg ccagctcaat gtctgctccg acaatagtat
    26881 ccttgccgtc aaccaaggcc ttaaattcaa aaggagcata gtcagggcta acagcaacca
    26941 ccagctttcc cttttcctgg atcctgtctt gaaggctcgt cttgttagct tggccacaag
    27001 ctgccaaagc aaaaacagat accatagcaa gtgctccaac taataatcgc ttcatgttca
    27061 tattataatt attccttttc ttgttgatga atcttattat attgcattat tattcaatgg
    27121 tcaagttttt attgaatatt tttcaagcac tgcgatagtc tgcttaatcc tgcctgtaga
    27181 acctgcggct gacagcaata gccgattctc acatgatttg cttgattaaa gcgatttccc
    27241 ggaacgacca aggtaccgta atcctccagc agcctcaaag caaaggcttc catgtcctca
    27301 tctatatcta gcctaacaaa ggccgttgag acctcattcg gtctatggta ggaggccctg
    27361 gcttcacctg ttatccagtc ctctaagata gcaaggttag tcctgataat ggcttgattg
    27421 cgctgcaata gcttgtcagc atgcttcaag gctagcgaag ccaccatatc atcaaaaaca
    27481 cctgcacaga tcattgtgta atctcgatat aacctaagct gatcacagat ggtctcagaa
    27541 gcggctaccc agccaactcg aatgcccgga atcgaaaagg tttttgacat gctattaaca
    27601 gtaatcccct tatcatacaa atctgccacc gctaaaagat gatcagaggt aaaggaatga
    27661 taaacctcat cacttagcag gtaaatatca tgctctctag caatattgat gagctcctct
    27721 aaataaggct tggtcatata ggcacctgtt gggttgttgg cattgttgat catgatcatt
    27781 tttgtgttgg gacgaatcat ggcacctagc tcattaaggt ctggcagcca agcctgctcc
    27841 tctctgatct gccaataatc aacctccact ccaagagaag ctggaatatc atatagctgc
    27901 tgatagctag gatagtgagc aatcacatga tcacctgctt caagcagtgc ataaataacc
    27961 aaaaaattgg cacctgttgc cccattggtt tgcaagatat ttctagcttt ctgctgctga
    28021 taaagccctg ccactgcctg cttaaagtca ggagagcctt ctatccagcc atagtctaat
    28081 ggcttttgat gcagctgctg gtaaaaggct tgaggctgct cctgtgttaa gtcaaagagc
    28141 tcctcaagcg ttaatgaagc aatagatgag ccagcaatat cgtatacagc acgtttttca
    28201 tgctgattta gccactcttc tacaccaaat accggtagtt tcataagatc accttatttc
    28261 ttgcgtaata tttattacaa tatcgcataa aaatacaatt gtcaaatcaa aaactatcct
    28321 ttttttgata agaatcatgt cctatctaac agttagtcct gattggtctc gcatgaaagg
    28381 ctactaaata gagcaaaaat cacataaaaa gactcccaac ccaccaatca gcgggattag
    28441 gagcctgata gctcgtatca attcattgat ttcagatcag agtgactatc atcactctac
    28501 tatgagccaa tgactaggct aggcggacaa cttctagctg tgatccaccc attaatacca
    28561 agtatttttc gatccttgca atcccgtagg attggctcag agcctcggca tataggtcca
    28621 tttgctgctg atagcgctgc ttcagctcag ctgactgctg atagcgatct gtcttatagt
    28681 caaaaagaac aatacgatcc tcaaaaagca ggtagccatc aataatacca cgcactacgt
    28741 actgctcctg acttaggctg tcttttttca gcatcgcaaa aggagcctcg cggtgtaggc
    28801 gctggtgatg ctcttgcagg agctgcccca attcagttgt cgcaaaaaaa gaggttacct
    28861 tttcaatgtc aagccttgcc ttgacctctg cgtcagctga gacaagctgt aaggtctgtt
    28921 caatatcacc agcagtaacc tgatcagaca ttggaatacg ctgcatgagc tcatgcaggc
    28981 ttgagccgac ctggctaggc tcaacagcct ttttcttaga aaaatcagga agctcaaagg
    29041 tcttgggcct atgataaggc tgatctatga tatcaacacc atcagtatcc attagaggct
    29101 cataaagggt tttaagctga ctgggggttc tcaccgtcgg cagctcaatg gccgcctgat
    29161 agcttgcatt gagctctgac accttatcca gcatgtctaa ggcacgcgca atgtcctctg
    29221 tttgacggtt atccttgaga tcatctgctt gcagcagccc tgagggcctt agctgaccaa
    29281 cagcttctgg tgttaagtca ctgtcatcaa caaatcgcac atcaataaac aagtcctcct
    29341 tgctaaatgt tgctgctatc gctagtagcc agtcttgaaa gctcagcaat ctttctcgac
    29401 tagctaaggc taagcgtcct tcggagctat tgtcggctgt tttttcctgt accttttcct
    29461 tgctagcctt accaatgagg tatacctttt tttctgctcg cgtcatggcc acatacaaga
    29521 gacgcatttg ctctgataag gtcgccaagc gtagctgctg cttattgagc tggtaaggaa
    29581 gagtttccat cgtaaccttg agcgacgcca atttttcttc tcttagaagc tcctttacat
    29641 tggcgacata tttgataccg attccctcat ctctatttag aatgattggc gcctgtaggt
    29701 cagccatcgc aaagcgcttg tcgcaattca aaatgaacac gtaatgaaat tcaagtccct
    29761 ttgatttatg aattgtcatg aggttaacag catgcttagg cctttcgacc tcaacatctg
    29821 ccaaatcatt ttgcgtctcc agcaccttat caatcatgcc aataaagcgt gagagtccct
    29881 tgtagcctga ttgctcaaat tggtcagccc gtatagcaag ggcgtaaagg tttgcctgag
    29941 cctgctctgc ctttggctgg cttgctacaa agtcaaagta aaagcgatcg ttaaaaatct
    30001 tccaaatcag ctcataaagc gaatgaagct ttgcaaattg acgccagtct ctcaaggtcc
    30061 catcaaaatc agccagcttt gtcatcagct cctgaccgat cagctctggg tgctcgcctt
    30121 gtcctctcaa gctattgcta agcttgtcat agaaggcttg aggctgcttt tgtgagctgc
    30181 cttgcagtga gattcttgcc agctgatcct catcaaagga aaacattggc gagcgcatta
    30241 aggccactag ggcataatca ttcaaaggat tgttgatgct tcttagcgta tccagcatga
    30301 ccatcacctc aactgatttg aggtaatttt cttggccacc atcagcaacg agaggaatgc
    30361 catactgatt aaagacctga aaaatagtgt catttcgtgt gcgtgacgaa acaagcaggg
    30421 taatatcttc aaaagcaacc ttctcctcgt tatagagcct gatgatttcc ttagccacta
    30481 agatgacctc acctgcggag ataccatcgt tagctaaggc ttcctcggtg ccttcttgaa
    30541 cttgatcggt gtcatagagc agcaattggg ctcgattgtt aggatatggc tgtctttgtc
    30601 cctcactgcc tgctaccagc tggtgcttgt catcataggt aatctctcct aaagactcgt
    30661 ccataaggcg gctaaagaca gcgttggtga catttaggac ctctgactga ctgcggaaat
    30721 tttcctttag taaaatcagc ttgccatgct cgggattgct ttgataatcc ttaaactttt
    30781 gattgaagat ttgaggatct gcttgcctaa agcgatagat ggattgcttg atatccccaa
    30841 ccataaaacg attatggcca ttagacagca gctctaatag gcgctcctgc atgtgattgt
    30901 tatcttggta ttcatcaacc atgacctcat gataatgacc ttggtaagct tggcgaatat
    30961 ctggagcctg ttgtaaaatc tcaatggcaa aatgagctat atctgaaaat tcaaaggcat
    31021 tttcttgcat ttttgcagcc aaataagcct ctgaaaagct gatcacaaag gcttgcagca
    31081 cctccaaaag tggtaagctc tcctgttgat aagcaaggat agtctccaag tgcctaaatc
    31141 ttaccagctg ctcctgtagc gatttgaaaa tagggtattt gtgaccggct acagttatat
    31201 cagctcctga aggaagtaaa gctgttagct cctgtgctag ctgacctagt cgcgctttac
    31261 cgtaaaggct gtcaaaatgc aaagcccact catataagct gtcaatcatt ttgaggtgct
    31321 tagtgtattt ggcagttagc ttgccagcct tggttgtttg agcgtaaccc tccatgtctg
    31381 tgaggtctcg cagctgatca gcagtgtcct gcatacaggc taagagagca tctacagctt
    31441 ggtctggaat atctgtaaag ctggtatagg tcttagaccc tcgtaaaaag acctctgcca
    31501 accaactgct aggattggca gttgattgac tgaaggcata aatgctatca acaatctctc
    31561 taaaggctga gctatcctta cgacgtccag aaaaattctg caccagctgt ataaaggctt
    31621 tattgtcagt ctgcgacata tagtcttcaa aaacctgacg aaagacctcg cgctttaaaa
    31681 tgtcctgctc tgccttatcc tgtatgatac gaaaatgcgg tgaaatccct aaaacataac
    31741 catgctggtg aaccaatttc tgagcaaagg catccatcgt accaatatca gcctgtgata
    31801 aagcctgcaa ttggtcatta aggtaggcct tgagctgata atcctgagtc tctgctatag
    31861 ctgtgtgcag ctttttttca attctctcta ttagctcagt agctgctttt acggtaaagg
    31921 tcgaaataaa taagcaatca accggaatac ctcttagaat cttatccaaa atgcgctcaa
    31981 ccataacaaa ggtcttacct gagccagcag atgctgatac taagatattt tgtccactgc
    32041 tataaatagc ctcaatctgc tgcgctgtcc gcttgtgcgt cttatctgat aaggcctcct
    32101 cctgctgcaa acgagcaata gcctctggcg ttagaaagcc ttcatcaatc ctcatgcttt
    32161 atctcctcat tcattcgtgt caagaaagcc tgtctccttt cttttgtcgg taggacgact
    32221 aggcgtctcg cgtaccctag atctaaatcc gcctcaaagc gcgtgatggc cttgagctgg
    32281 tcaccctgaa cagacttgcc gtctgcggta taagggttta ttaggaaatg ccctgtttta
    32341 atctgcttca ccgcagacaa atatagctgc tcattataag ccagcagggt ttctagctca
    32401 tcagtctcat aaagtgtgtt gttaaggtga tagctgccat tagccagata ttccttggct
    32461 tgggctaaaa aaatgccctt ataggttaac tccttgtaag ccgcagctac tagctgatca
    32521 tcaagtgcct taaagtcaga cagacttagc cttggctctt gcatgtgcag gtacatggcg
    32581 ccaaacaggc cctgcccctt attctttagg gcagcaagat aggtcacaag ctgaggactc
    32641 aagccattgt aaaaggcaac aatgtcaaat acccttgcac tggatttgta gtccacaatg
    32701 cccagcctac catcagctag ctggtcaata cggtcaataa cccctcgaat aagcacttgc
    32761 tgacccagcg ctagctcaaa ggcctcctct tgcttggtta tctgcaggcc ttgattaagg
    32821 tctaagacag aggctgttga gtaagcaatc ccctttagga cctctaagct atatcgccct
    32881 tcagcatcag cctgataaac ctgctgaaaa gcgctttgct gattaactgc tgcaatagct
    32941 gcgcctagct tttggtcaaa ggcagcatta gacctatcct tggttaccaa ctcaaaaata
    33001 cggtgcaggt attgaccatg aatgcgagca tctgggtgaa tagactctgg ctcttgcagc
    33061 cctaggacat atttcaagaa atacttgtat tgattgttat aaaatacagt caaggccgat
    33121 gaagacagat tcaagggctg ctgacttgaa aagcgggtct caataacctc aggtgctact
    33181 ggcttagtag tcaaatgatg ctcaaaagct ggaagactta gctgctcatc ggctagccta
    33241 cgtttcaaat aacgaagggc aaccgtccaa aagtttctgt cctcactggt catgtcatct
    33301 gcaattccct gccgattaat agccaccaag cgagacaaga gagccttata attgccaata
    33361 tctgccgctg agtgtgacaa acggttcttt cctttttcaa tgactggaac accaagggca
    33421 attagctcct tcaggtaagg agagacatca tctgagctat tcgttaagct tgtaggcagg
    33481 cttaacacca gctcctgcgt cgctgcatta aacagggaaa gtgctgtttg gtgatttttc
    33541 ttgatatttt caaagctcgg cacatcaagg cgctggtaag aggcagtctg ctcattgatg
    33601 cttgcccttt cctgatcaga gatcaggctg gtgttttttg tctgcttagg aaaatgggag
    33661 cgactcaggc caatcgcaaa cacaaagggc ttggaatgcg gctccaccag atcataggat
    33721 ttgatagaca caacatctaa ggtcgcaggc actgtccgat aatgtgctgt ctgcatgccc
    33781 atcttgatca gagctagaca gtctgcaagg gtcatttttt cctgaccaaa cacctgataa
    33841 aaggtctcta aaatgcctgt gaaggctttc caaacctcct cgtccttttc cctatcagtc
    33901 tcccttctac tgcctgctag tgcctcaaaa ttatcagcca gctgaatggt cttaaaaaag
    33961 gtcattagct tatcaagtag ggaagcccct agctgctttt gactcttaaa gagctgctgg
    34021 agaggagtca ccacagcaag tcgcagctga ttcaaaagag gcaaaggata ctgacgtgag
    34081 gaatttaggg taaagggtct tgaaaatttg gtgaagcctt gaatatcagc aaagaccaag
    34141 tattgctcaa gctgatccag ctctccctct tgaaagcgcc caaagagtcc tgattttagt
    34201 aagttgacaa tatcctcacg tcgccaattg tatctgcggc ctctttctaa ggattcgaca
    34261 aattgaacca aggggtgagc agacatcggc tcttgcttgc cgatataata agggatctca
    34321 aatttctcaa aaataggacc aatttgcagc tgataagacg ccacatcacc taaaaggaca
    34381 agcatatcct tatagcgata accctgatag agcttctcac gaatagcctt tgcaacatgc
    34441 tcaagctcct ctttttgatt gagcgcttgc cagatcacaa ccttgctctt gtccttggca
    34501 ctgagctgcc aatcaagctt tgaatagtca tgattggctt caagaagctg tgttaggcga
    34561 gaaaatgaca catcaaagac cttttctgac gttgtgtaga tcggcttggt ttgaaattgc
    34621 tgtgccagct gttggataaa cgcaaggctc gcctcgtaga gatttccctt ggtaaaggct
    34681 agtcgataag ccttttgact gatataggct ccaataacga tttcttcaca ggcttcgttt
    34741 aagagcgcta gcagctgctc ctcctcagct gaaaagcggg taaagccatc aatcactaat
    34801 acggtctgcc ttagctcgtc atctaggctc ttgcttttga tagcctcagc aagctgagcc
    34861 agcctacttg actggtcgta atctccttgt gcaatcagct gctcagcctt ggtcataatc
    34921 gtgatcaggt cctcttgctt ttctggtcta tcaagcgtcg ttaagtcaaa ggctgtcaga
    34981 ttagctgctt gcaattcctt atatagctca actaactggg caataaaggc ctgatctgtc
    35041 cgtagccggt gaaaaacctt tagctcatct tcttgcagct gcatgagcac acgataaaaa
    35101 atcatggcta agccattatc atctaacgct tgtcgattag ctgccttagc taaggtaaaa
    35161 taacgcgcca tctgctcaaa gcgggtcacc gtaatagcaa aggaaccctg ctctggcaat
    35221 aaggctagga cagaacgttc cttttcaaag gatagagagt taggagcaat ataaaagaca
    35281 cgatagccct tatcagcata agctcttgcc tctttgacta aaatctctgt catggaatag
    35341 ctaatctctg tgtatagtaa tttcataaaa ctccttttat ttggacctga tacaacgtct
    35401 atgcctccat tataacaaat cagccttgct tttcccattg ttaatgatct ttcaaacgcc
    35461 acaagaagcg ctcacagcat gaaaaaagcc taccatttca catctgctgc tttgcgcaag
    35521 aaatgataag gctttgtctt gtataggctc aaaaaacaga ctaagagctc ctagttaagc
    35581 tgccctgtgc ttgtctcttg tgatctgtcc ccaggcattc tttttacgct gataaccaat
    35641 aaagctgctc accttgataa gggttaatac cgtatgaaga acaaggcatt ggtagatggc
    35701 agcatagatt acccaagcca tatcaaaaag agtaatgcta ctattgtttt gcaaataaac
    35761 cctatttaaa aacgatgtca acgcaataag cacacaatag caaatataga gcagcatcag
    35821 tgacacaaaa aaggttgtgt ttaattgatg gcatagcaaa gacagcacaa tgataataac
    35881 accaaatgcc tcaataaaag gagataaaag ctcaaacaaa agatacagca cataggaaat
    35941 gagtaccgtc gctttaaacc gacagcttac aaaaaactgg agatactttt tcaagcattg
    36001 atacagtcct aaaaaccaac gacgcctttg ccgacacaaa tccttcaagc gactgggcgc
    36061 ttggctccag caaatagcgt ctgtttcata gccaatacga taaggaatct tgttgttatg
    36121 gcagaaaaaa tgtaatttca tcaccagctc catatcttct cccagagtcc cagtgtcata
    36181 accatcaaca gcaatcgcaa gctctttttt aaacagtcca aacgctcctg atatgattaa
    36241 attcccagca gcctggtcta ataaaacacg agctccaaaa aaggcacaat catactcaat
    36301 tgcctgcgca cacgaaataa gctgacgcgg caaatggtag tctacgatcc tcccagctgc
    36361 caatgctact ccctgcgaaa ccttgaccat gcccccaaca gcaatgacag acggatcctt
    36421 tgcagcagtc tttgcaatac gcttaagcga atcctcctgt agcatcgaat cagcgtccat
    36481 gcacaataaa taatcgtatt gagcagcgtt aatcccaaga ttgaggctat ctcctttgcc
    36541 gccatttgcc ttttcaagca gggtcagctt gatatgcttg agctgctttt ggcttacagc
    36601 ctttagaggg cgtgttggga tccgctgatt aatcgaacaa gtcaccgctt ctaaatgaaa
    36661 ctgctccttc aagagcttgg cggtatgatc tgttgaccca tcatcaatga caataatctc
    36721 atagcagtca taatcaagca tcagcaagga ctccactgtt tcgataatgg ttagctcttc
    36781 attataggcc ggaaccaaaa tagacactgg cggtaaagaa acatcaccac caacaggcgc
    36841 ttgctgtcgc ctttcataaa ggtgaatagt cccaacaatt aaggatagca gtaaaaagct
    36901 cgcataggca atcaaaaacg ctaaaaaaag atattgggag tatttcaata ctaaaaacag
    36961 tagctgcact atcattctcc tttaacatgc aatcacttgt gcttaccatt cgccttacaa
    37021 aagcgtctca aggtctgctt catcaaatac ccgatattaa aggcaaggat cgctaagcaa
    37081 acgattatat aaaaaaacaa caggtaataa atcatcttat cttctcctct tttcctgcca
    37141 gacagcctgc acctgctgat aggaggtctt taaaacttct cttacccttg gacgctccca
    37201 gctcaacagt ggatactcta ccattgcaat gacctttgat tcctttagcg gtgcaaaacc
    37261 aatagctatt gcttcaatgg ctaattcctc aacaccatag tgctcaaaat aatcatcgtg
    37321 tattttgttt gaagctggat cagaaaaatt gagcagctgc cagggaatcc taagctcaat
    37381 cagacgctcg ccaaaagaaa tatcggtctg cgaatcaaaa tgagccgagc ctcgtttgcc
    37441 attgccctgt tttaattggc cggtagggta gcgcttcagt cctctttttg caatcggaac
    37501 ctgatcaatg gctgcaaaaa taccatcatt tctcaccacc atatcaacca tagtaaatct
    37561 tggcgtatgc ttgttagggg gaaagacata aaagtccttt ccattaatct gcctaaggta
    37621 attggcatca gtagcatggt agcgctcctg caccaagagg cgactgcctt tgtggtcatc
    37681 aacaacaagg gcaaaatcag caaagcgatc aaaccgagcg ctaaagcctt caataaccct
    37741 gctgcctgtt ttgggcgtaa tgtctaaggg aatgagccac tgtctttgta agggctgctt
    37801 ttttgtcgat tcaatagcaa tatagaggta tttttcgtcc tgatcaacga ggagctgctg
    37861 cccatttttc ttgtaggtta gagctctaga ccactcatct gctgcctttt gcccatcaat
    37921 agcatgcgtc cttggagcat gctcaaaggt taagagacca taaccttgag ccttagactg
    37981 aacatcaccc caaagaaagc tttgatgttt attggttgca aaggaggtat tccagctcct
    38041 agcagtccaa tcgtcctgcc agctatggat cgttgcacca cagcagccag acgcaataaa
    38101 ggctgtgtaa tctgccatca agcgctcgcc ttgatccttt tctgtcaaag ggctggaagt
    38161 cgatatcatt tggtccacac ctctggctgt cgaatagcca tagcccgtca caaccactgg
    38221 gacacgatga tagctcgtca gtagcttgac gtatccctga tataagggca tgcgcttaat
    38281 atccccaaca agcctatcag taagccctag acggtcaaat agcagataat ccctataagc
    38341 cgagtgacaa tccaagagct tataggaagc aaaaagaccg gccttaacct tagcgctggg
    38401 cttaatattt tcaatcgtca gttgaacata ttttgctgcc tgagaggcaa agggatcctg
    38461 atagacaaag ggatctgatt gaggcgtatt tgaaaagctc accaagtgct gccagccata
    38521 tttgcggctc tcgtatgacg tgatttcctc catgatttca gccagtatag cctcaaaccg
    38581 attggcctga ggtgtcgttg cataatacct tcccttaaag cctacaggct tggcgtgatt
    38641 ctgatgattg gtataggcta tcgtcccact gtaccaatca tcaccaacaa tatagccgag
    38701 tagccattta ctcatatcct gatcataatg ctgaagccct aaatccgaat gccagatccg
    38761 ttttctccca tgaatcacat caacactagc cctagcttcc cttaacagag tgcctaaata
    38821 agccttatct aaggcgctga tagaagaatt gtcatgataa gcatctattc taaagccctg
    38881 taataggtac agaggatgac ttgctctgtc attgtagcgt ctcaaagcat ggtaaaaagt
    38941 gacgggcata ataaccctta ccctgatcgt atttgcaccc atagctgcta tttgcttgaa
    39001 ccacctatag taggttttct catcaacgct aaggtctcgt cgacgatagc ctgctatgga
    39061 actctccaca tcaacaccct tgatgagata aggagatccc ttttgatcat atatgcgctt
    39121 gtccttggtg taaaagactg tccgaatagc tgactggtta gagaccggca ggtacaagcg
    39181 accatcaata tcacaacaat aatagctcaa gccaatcaca gacaagagca aaccaacaaa
    39241 gattaaatat ttcttcatca ctacctactc caataatgta ttggtatttt tagacggtgc
    39301 actgtactga tagagcgtct caatatgctt atccagccat cgcccacgac gtctaataaa
    39361 gtcctttagt tgcttaacag aggcctcata gctactgtag ttacgactgg ctggcacaag
    39421 gtaattagtg gcatcgcttc ttgatggcac tgtaaacaca tagccccact tatgataatt
    39481 gcgctgaata gccggaccta aaaaagcaac cgtagcatca atatacttga tcaaataatc
    39541 cgttgataaa acattctgtc ggagctgatg ataccttgtg accaccagct taacaaagct
    39601 aggatccttt agcagcatgc aaaaccaagg agcatctgat agggtaaagt ccgcctcatc
    39661 ataaggagcc tcaatctgat tatcaaaggc gttgttaaaa tcccagacca ccagcttgag
    39721 cttatcgcgc aaatccttat aaagataggt tgaaaacttc ccagcatcaa tatttctaaa
    39781 gaattcattg ataataaaat agtctgcaaa ggactcttgg tccagataat cagtgtattg
    39841 ctttaaatca taagaatata ggagcttttc gatatgactg atatcctttt caataaactg
    39901 cttttgctta ggcgtcagac ggtgcaggct tgggtattta atgtctaaag aggacagacc
    39961 tgcttgattc gtataggata cgtaatgatc aagagcctgc ttagccttgt gtcttctatc
    40021 ccaaacaagg atataaggcg ttttatcaga ttttctatca cttttttcga tgtttaccct
    40081 atgccgcccc tgctcaatac tctccacagc caaatacaga ccacaatact gatgatccac
    40141 cactaactcg caatacctga cgttaggtgc ataggtcatg atctcaccgg caatattgta
    40201 gctaagataa tttcggacta gggtccgatc taaaaaagga ccatgcagca cccactcaga
    40261 ctccttggac atgccagcca gcgagactgc ctttggctta gctcttttat tgataaacct
    40321 tagctttaag gatttcttgt caaaatgacg tgacgaattg cccctataag caatcaatgc
    40381 tgtcaaggac aagcgcggag actcagacag gctgtgctct ctatctagct gatcacgaag
    40441 cgagaccgtc gttttaatgg ttttttgccg ctttgtctct ccctcgtatt ccctttgctc
    40501 tggaatctgc tgatgatgag tgtcaatgct aataatcggc aaatgagagc taaactcccc
    40561 agtgcttctg gagctctttt tgaccgtctg caaatggtga tgaatacgct ttgcagaggt
    40621 cttaggaaaa ccgataccac aaatagcagc tagcaagaga cacaccagca caatcacata
    40681 aatcgtcttt tctttcattt acgtcaacca gttatgtcat cgctttgact aacaatatta
    40741 aaataatcaa ctcgccccag ctgataaaca gcctcagtta acggattagc ctgctgatag
    40801 gtgctgtcat aatcctttct tgacagctca aagatcatct caatatcatc agacgtggtg
    40861 tttttcacgc tctggatcgc cttacccgaa aagtagttaa acactaaccg ctccagctca
    40921 atttccattt gcttatcaca gcgaacaatc aacaacagtc tattgtcatt tctgacagct
    40981 cccataagca acaaaagcat aaagatcacg ctgctaccag ttgcagcgac agtataatca
    41041 ccaacaccac agcaaatccc aaccacaatc gtccaaaaaa tatagactgt atctctagag
    41101 tctttgattg ctgtccgaaa acgcacaacc gacagcgcac cgaccatacc aagagacaaa
    41161 gcaacattat ttccgataac tgtcatgacg gttgctgtta agaccgtcaa ggtcatcaac
    41221 gaaacattaa acttcttgct ataggcagtc ccagtgtggg tataggcata tgacatataa
    41281 atcacaatac ttaacaaggc tgcagcaaca atatgcagca aaacatcttg aaagctcaag
    41341 gtcccacgct gttcaaagac atgtcttaat aattgtttca tcttaatatc tctcctaaaa
    41401 acgataatgc ttgctgatag ctctccccat gcaatacttg cttgcactta gctcgctacc
    41461 attaacagac tccaaaagct ttttgatata agacaacaaa aagccattat acttgacctc
    41521 caagatgacc aaatagggat ctagcaggta attctgaggc agatgatctg aaaaaatatc
    41581 agcattggtc tcagacccga taatatgatg atcaaaggta atgcgaatat tgttttcctt
    41641 tgccacaaat gccttgcgct ggtattcgat cactgttttt ggctgataga gctgcattga
    41701 catgcgacta tagcattcag cagcaaagcg atcaggataa gtcagcaata tagacttgtc
    41761 tcccttaatc aacaattgag cgtctgctct ggtcaacctc agagatcgct ttttttgatt
    41821 gctcccttgc ttttgcttca tctccaactt agcaaatgag ctctgactac cgtaattgcg
    41881 caggcgaatt tttcgcctaa gctcaatacc gtcctctttt tcctgccagt caacgtcctc
    41941 caaagaatca aaatacaagg atcgaatcac atatccctca ctagagctat gagcatctag
    42001 acgcaagagc ttggaaaatt catgcgataa gcgataataa tcctcaatgg taatcaaata
    42061 ctttttttct tgacgcaata cctcattcac gccagtgtcc tcctttttcg tctgtaagca
    42121 atgccttaac accaagctgc ctgtaacagc agccaacaaa cctgtctcat aaataagtca
    42181 gggcaaataa ggtgattgtt ggctctacaa gagtcaatca cctgccaaaa tagtaaatcc
    42241 tgccatctgt tgaaataata taaaccagct gatcgtcttg attgcaagac aggcgctttt
    42301 gtgactgatc tagctgtctg ctgctaatat cagttgcatt agcctccttg agcatggcct
    42361 gcttgagctg ttgctggatt tttctggctt gcagctcaga aatctcaaag ctgccattaa
    42421 ccttttgagc cttgtgcttg tagaccagtg ccacatggtc tttagctgtt gtcctagcag
    42481 tcgacaggag cccttctttg ttgagctgag tatgctctcc tacatcaatg gcaacatagt
    42541 catagggtgc ccgtatccgg tgcgctgtta gtattgagga caaaatccct gtcacaaggc
    42601 agatgcttat cgtagccact atcatctgct gccgctgctt acgaatgaac cttgaaaaag
    42661 cacagacctc cgcctgatat tcctgaagct cttcttcaac cttactgtaa tcctgtctaa
    42721 gatcagccaa gtcagtctga cagtccttgc agcttgtcag atgagcctca acaaccgctc
    42781 tactataatc actcaacgta tcatctacat ataatggcaa caaatcctgg atcaactcac
    42841 aatcatactt catagccata ctcctctcgt aattgtcttt taatatgttt tcttgcccta
    42901 aagacaagaa ccttggcaga ggatactgtg atgccaatat ccttagctat tttttcatag
    42961 gaatctcccg aataaatcct cgccagaaag acagcctgca ttttctctgg aagattaaaa
    43021 ataatcgtta gtgtaatctc taacagctcc cttcttgcta tcttatcaag tggttcatca
    43081 tgccctttag catcaacgat ttctaagctt tccatcgaca tattctcata ttttttcttt
    43141 ttaatttctg taaagaaggt gttctttgca atggtaaata accatgtttt gattgaacta
    43201 tccccactaa atttagcaat attacgataa gcctttagaa aagtctcttg agtaatatca
    43261 tctgataaac tattttgata acagcacagc ttatttacaa acctataaac atcatcttta
    43321 tattctaaat atatgtcctc aaattccaac agcttgtctc ctctcaatac acccttaacc
    43381 attagaccgt ccaatctgcc aaaagttaca gattaattta atttttagta taagctgtca
    43441 tcaagtcaga taaatagtaa tgatctatca tcttattatt gactcaaacg acaaattata
    43501 ttgcatttta gtataagctg tcatcaagtc aggtaaataa caaggacata tcatctaaca
    43561 tttgatccag acaaaaaaga cctgattctg taatatacag aaccaagtct ttctcaatag
    43621 acattgacta gatgattgat ttatagcgac atagctagat aggctatgac ttaccgtctt
    43681 ttggatttgg agacaagccc gccaagacct gccaagatac cactgccagc aagagccaat
    43741 aaagcatcta gctgactagt gcctgtttta gggagagtct tagctgagaa ctgagaaacc
    43801 tctccagcag tctgagcagc aactaatttc tcctgatgat gggctgcttg atcagtcatt
    43861 gcacctaaag tccccttatc agactgggac gccctaagac ggataatggt agctgttaag
    43921 cctgatagct tgaccccgtc cttggttagc acaaccccct caggacttgc cagcgcctcg
    43981 gtgcctgctt gcttggcatc gacgataacc tcaccagcaa gaagagcctg aaactcacca
    44041 gttagcctaa tggtacggtc attgctatca gcattgacaa agacagcata aacatcacca
    44101 ttgcttgctg ttgtctgata agcaatcacc aaatcctgtg ccttgatccc atgctcattt
    44161 ggaacagtga tcagcttgac cttctggtct atctcagcct tacttgccaa gcgaaaggca
    44221 tctgtcgaac ggcgcagcgc aatcaatccc ttagtaaagg cctgacttgt cgtgctttca
    44281 gggtagcgct ctgtatccgt tgcctttgcc cagtcaaaat gattaatggc atctgtcgaa
    44341 tcataggaat catgaataaa gtatgggtat tcaaatggtg ttccgtcctc attgaccaag
    44401 aggtgtgatt tatttggcac cttgtcatca gcgaccttgc ccttataggc ttcgtcctta
    44461 aattgctttg tacgaccata ttcctgacca gcatgtagga aaggggtgcc ttgagaggtt
    44521 agcaccaaga ggttccctag gcgcaagcga cgatgaatct ctgccgcatt tgctgcaaca
    44581 gacggatcct ttttaataga ctgggcgata atatcaaaca aggtcaggtt atcatgtgca
    44641 gcgatatact gaatcacatc acccggatca tcagccaaaa agttagtcgg ctgagccttg
    44701 atattatgaa aaatggtcat gatatcccta gcaccgcccg taataaaggc tggagagcct
    44761 tcatttggaa agcctgattt gagctgattg cgaaaatcat ctgagaagga ggcaacggta
    44821 tctgtctgtg acatccagct ttggtccgca ggctgctcag gcatgtgctc atcaccctga
    44881 taggtgaccc agccctcacc aagcatgatg atattcggat taagtgcctt agctgctaaa
    44941 aaggcttttt caatagctgc tgcatcatgg tcccccatca tgtcaaaacg aaaaccatca
    45001 accttatact catccaccag ataagtaatc gaatccacca aaacacgacg actcatgtaa
    45061 tgcgttgtcc caagtcgtcc accaccaaat gaggtcctag cagtgccatc agcattcata
    45121 aagtgataat aattcggctc caggtcctca aaaatatcaa cattagctgt atgattgtag
    45181 accacatcaa ggataacccc cataccacgc ttatggattt cattaacaag ctgcttaaat
    45241 tcctcaatgc gcttagctgg gtcggttgga tcagtcgaat acataccagt caaggcaaaa
    45301 tagctttgtg gatcatagcc ccagttgtaa ttattatcac ttgagctgta ggtcagcata
    45361 cgctccttgt tggccaattc gttgacaaaa taatagctca tcacaggcag cagttgaaca
    45421 tgcgtaatac caagctcctt gagataatcc aacttttcaa caaaggcagc aaaagtccca
    45481 aattgagcct ttagatcatt agcaatcgcc tgatctgagg taaaatcacg aacatgtgcc
    45541 tcatagataa tggcgtcctc acgcttatga aagcccttaa tatcagcaaa ggccagctcc
    45601 ttatccccaa tagcagcagg atcaacaatg gccgccttag ccaccttata ggacgggtct
    45661 gtcttagcaa gctcgctgtt ccatgccgct aacgatttgg cataagggtc cagcacaagg
    45721 acagacttgc catttctagt aatctcataa tgatagaaat agcctctata atctgaaatc
    45781 ccaagtccgc tatctgctga tagagtgatt gaccactctc ccttatcacc ctttgctaga
    45841 gcgagattac caatcacctt ggtctgatca gccttatcat acaaaacaag tgacacctta
    45901 tcagcacttg gtgaccaaat cgtcagatca accttagcac ctgcttctct cacacgcgct
    45961 cctagctcac cgtcataagc atacaggcta tccttgtatt gccaatttgg cctagcctgg
    46021 aagctctcat gatgaaaggt caccgtataa gtggccactg cttgactaaa atcacctgtg
    46081 atgacagcct tatgagtctt ttcatctaag gtgatatcag taatagcaac tgcttcctta
    46141 ctgtcagtgc tgatttttaa ttcttttaaa aggctttcct tatccacatc tgctagagtc
    46201 gtaaagctcg cctcaatact gcttgggctg acctgctgag caccgattaa tctaactgta
    46261 ttaacaaaat aagggttcgt ataaatggtt ggatcctcgt ctttcaagaa aatttgggtg
    46321 tgattcttta aatctttaaa aatataatca ttgggctgaa ttttaacagc gtcacctgtc
    46381 tgacgctcat ctagcaagag aaagcctagc tcattggtat cagctagctt gacatctata
    46441 taagcaccat atcgaccgac ctgcttaaaa tcaataccat ctggccaagc gccctgctga
    46501 ctagtcattg acgcatcagc acttccccaa agccagagcg atttgttgtc ataatggcca
    46561 tcactgcgat aataattgat acggatatag ccctgagcca gcggccgata gtaagacagc
    46621 tcctggccat caatccagac ctcattcatc ttagggctga gaaggtctat ggttcgatcg
    46681 cccgtcagat tgtctccctt agtgttattg atcaaaaagc taaccttatt ggcttgattg
    46741 gctgaaagct taacgtccat gtaatagcca tagtcatctg tcttcgctag actaaaattg
    46801 gtagccccag tcggccagcc tcccagctga tcagatggtg tctcaacatc gtcccacacc
    46861 caaagaccaa gcgaggatag gtcttgagct ggcagggtct tgaaatgcag ccgcaaggtc
    46921 tgctccgcta tcggctcctc tgagcttgta gcttctggtg tctctagaga gctgtctgtc
    46981 gtaacagaca ctatcgatga tgaaggctga gactggtctg tagtttcctc atgcgcctga
    47041 tcctctacaa gaggtacagc tactggctga acttccttga cagtatcagc attgacagca
    47101 gctgacacct tagtcacatc agaaatacca gcaatatcac taatgtcagt agcttctggt
    47161 agctcatttg agccttggtc agcagcctct gacttgacca tgaccgcacc atcagcaggc
    47221 tcaacactcg tcagactctc agctgctgct gtgatctgcc cactagctgt ccccaaagaa
    47281 aaagcggttg caatagctac cgaagccact ccaagcttaa gcttacgaat gccaaataat
    47341 tgacgctctt caaacagcgc ttgattttcc cctaaccttt tcatcattcc tccgtcctta
    47401 tcctgatagt tattaacacc ttaagtatac aaaagaaatc acaatagtgc aatcgttttc
    47461 tttattgaaa acaatgatat ttatgaacaa attagacaag aatcaacgca agcgatttcc
    47521 ttactgataa atacctgctc ccctcactaa gaccagccca ctgcaaagca gaaaagtagc
    47581 ctaaagagcc ttagtaacag ataaatgagc ttaatgttgc ttcatcaact agctggctgc
    47641 aaccgttttg ctctgatgtg gtaacgtctt gtcatcatga ctaagcttga caaaaaacgc
    47701 tgttagttac ataatcaacg gtgcttggta gccttccatt actcctttga ttgttatacc
    47761 ctaatgatac acaaaacctc agtttttata gtagaatatt acactttgtt ttgacaaaga
    47821 tgtttaatct tgctaaaata aacttatcaa tgagggagta ccaatgatga cattcgaatt
    47881 cacatcgtta ttcgatttac aaactgcttt tccaacagag caggcttgca taaatcattt
    47941 agaaaatatc acttggggtg acgtggtgat cagccctttt gacgctacct caaaggtcta
    48001 taaatgcaag ggaaataaat accgttgcaa gaatacaggg aagtatttca ctgtcaaaac
    48061 aggtactctt tttgataata ctaagattaa gctacaaaaa tggtttatgg caatctggct
    48121 tgtgacttct cacaagagag gaatctcctc agtgcaatta tcaaaagaga ttgcagtgac
    48181 acaaaaaaca gcatggttca tgttacagcg tattcgtaaa tgctttggct ctgaaaactg
    48241 agatccactt ggtgacgtcg ttgaagtaga taaaactgat attgatggta aaaataagaa
    48301 ccaccatgat cctaagaagg caaaaacgtt caagaaccat ccttctctga aagataagtc
    48361 ggcagttatt ggaatggtgc aacaaaaaag taaggccaac gctcatacaa tactcgtgat
    48421 tactctgata gtcggcgttt tatcttttat cagctaatgc tgatatgcga acaacttata
    48481 aggagctgat caatggttaa acatgcaaaa actaacctac actttgaatt agaaagatct
    48541 atctctcgca aagttgatag taaattgata gcctatcaag tcagtctttc agatggcttt
    48601 tatgacaaat acaccaaatt atgggataaa acctattcat ttgattttgt catcaaccat
    48661 cgtgcgtttt atgctcagtt gaccaaaaga tgtgtttacg atgtcctttt gcaaactttg
    48721 gaaaaaatca gtagaaaagc cattgcaaag caactagcag agcttgaagc cttggttgat
    48781 gtttcggaaa gtaaggaaga ctttcagata tttttcgaga aaaaatacaa actatcattt
    48841 cctgatttga agaattgtgt ttatccaaag aaaaaggaac tttccgattt tgatcaaaac
    48901 ctctggatag ctctacatta taaccctaga aaggagaggg atacataatg acaacatggt
    48961 atgattacat ggtaagagcc agcgaacact ctggaagtga tggagacctc tggtttcgtt
    49021 acctttacaa ggttatcaaa gacaaagaaa ccaaactaac tactgatgat gtggagcagt
    49081 tattaaaaaa tccgaatcta actccttttc agaaggtaac tctgcaagat gctttaacag
    49141 aaggtacgca tacaagagag catgttttac aggcaaaccg taaaagtcag ccaaaggata
    49201 ttttgaaact ctttagagag ggaaactatg gataaaaaaa tcttattcaa agctctgaat
    49261 acagaactag ctaaagaaaa tattagcctt gacattatct gtgtcggtgg ttttgtcctt
    49321 gaatattaca atctgcgagg aacacaagat atcgatgcct tttatcaaga aggtgttaac
    49381 atcaggcaga tgatcaaaaa ggtgggagat gagtttggcg ttaatgaacc tgatgagctt
    49441 tggcttaata attcagttgc caatcttaat agaataccac ctaaaacgat ttgtgagaca
    49501 gtatttcact attctaacct aattgtcctt gtcccaccct tgtcttatat tcttggaatg
    49561 aagctagaaa gcggacgaga tagggataga caagatgccg gagacattat taagctagct
    49621 aatatccgtt cccctaaaaa acttatcaat acacttgaag agtatgattt tcaacctgat
    49681 atttcaatga ttttagaagt ctttgaaata gcttatggca tggaatggtt agcaaactat
    49741 atgaccgaac acccagaaga atttaggcat tattaaaaga cgatttctgt ttggaagtcg
    49801 ccttttttga tgtttttgaa aacaccttga gattagtcta aactaatctc cataagcaaa
    49861 aaacagctta gccccgtctg ggagtaagct gtttttgctg taatgtatga gataattagg
    49921 ctaacatcaa tcattacata aagggaataa agggttaatg tttcttgcgt ttgcgtgata
    49981 ctacagctac gcctagactt gccaatacgg caagggctgc tgctgtaaag aatggagctg
    50041 ttgcttctcc tgttgacgga agcttgtgtt ccattgcttt aggtaccgct ggtttatctc
    50101 ctttctgtgc ttc
//
LOCUS       DARYXS010000003        48689 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.003, whole genome shotgun sequence.
ACCESSION   DARYXS010000003 DARYXS010000000
VERSION     DARYXS010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48689
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.003"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            110..637
                     /locus_tag="TV193_000110"
     CDS             110..637
                     /locus_tag="TV193_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEL1512353.1"
                     /translation="MSVDDYRPTYAVEAVYDLRANDLLRQGITAVLVDLDNTLIAWDN
                     PDGTPEVRAWLDEMTIADISVVVVSNNTYSRVERAVSRFGVDFIARAMKPFAYGINKA
                     IDRYGFDRDEVIMVGDQLMTDIRASHRAGIKSVLVKPLVTSDAWNTKVNRWRERRVLA
                     KLEEKYGRLVYQKGI"
     gene            637..1755
                     /gene="yqeH"
                     /locus_tag="TV193_000111"
     CDS             637..1755
                     /gene="yqeH"
                     /locus_tag="TV193_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEL1512354.1"
                     /translation="MEELFCIGCGIQIQTTRKQEAGFTPAAALVKGIEAREIYCQRCF
                     RLRHYNDITDVHITDEEFLRLLHEVGDSDALVVNVIDIFDFNGSVIPGLSRFVAGNDV
                     LLVGNKKDILPKSVKDSKVTQWLTERAHEEGLRPLDVLLTSAQNKYAIKELIERIDQL
                     RQGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSAKNLKFISPKKEIKPKTYQLNPEQTLFLGGLARFDFISGERQ
                     GFTAYFDNQLLLHRTKLEGADAFYDKQAGQLLTPPDKKELDDFPRLVRHEFLLDQKVD
                     VVFSGLGWIRVNANKETATKVAAWAPDGVAVVVRKAII"
     gene            1782..2123
                     /gene="yhbY"
                     /locus_tag="TV193_000112"
     CDS             1782..2123
                     /gene="yhbY"
                     /locus_tag="TV193_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEL1512355.1"
                     /translation="MLTSKQRAFLKAEAHSLKPIVQIGKNGLNDQIKTSIRQALDARE
                     LIKVTLLQNTDETIHEVAEILEEEIGCDTVLKIGRILILFKVSAKKDNILFKVSAKKD
                     NRKLSVKVKSI"
     gene            2207..2839
                     /locus_tag="TV193_000113"
     CDS             2207..2839
                     /locus_tag="TV193_000113"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEL1512356.1"
                     /translation="MALELLTPFTRVELEMEKKDSNRKQVGILGGNFNPVHNAHLVVA
                     DQVRQQLGLDQVLLMPEFKPPHVDHKETIDEKHRLRMLELAIQETEGLAIEEIELTRQ
                     GVSYTYDTMKLLIEQNPDVDYYFIIGADMVDYLPKWHRIDELIHMVQFVGVQRPKYKA
                     GTSYPVIWVDVPLLDISSSMIRDFIQSDRQPNHLLPKAVLDYIHKEGLYQ"
     gene            2836..3429
                     /gene="yqeK"
                     /locus_tag="TV193_000114"
     CDS             2836..3429
                     /gene="yqeK"
                     /locus_tag="TV193_000114"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEL1512357.1"
                     /translation="MMYQDYVGYRRDELLGKIAEQMSDKRFKHVLGVERAAIHLAERY
                     HCDPIKAGLAALLHDYAKECPDELFISLIDKYQLDPELLKWNNNIWHGMVGIYKLQED
                     LGLKDKGILRAIEIHTVGAAEMTILDKILYVADYIEEGRVFPLVDEARRIAELDLDKA
                     VAYETAHTVAYLASKAQPIFPQTIDTYNAFVHYLHEE"
     gene            3431..3784
                     /gene="rsfS"
                     /locus_tag="TV193_000115"
     CDS             3431..3784
                     /gene="rsfS"
                     /locus_tag="TV193_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEL1512358.1"
                     /translation="MRKEELLEIVIKAADEKRAEDMLALDLAGLTSLTDYFVIVTATN
                     SRQLEAIADNIRERVKEASGDASHVEGNSQTGWVLLDLNDVVVHIFSEDERYHYNLEK
                     LWHEAPAVELSHYLG"
     gene            3914..4657
                     /locus_tag="TV193_000116"
     CDS             3914..4657
                     /locus_tag="TV193_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1512359.1"
                     /translation="MQKNYDTFASVYDAIMDDSLYDKWTAFSLRHLPKNKEHQKLLEL
                     ACGTGIQSVRFAQSGFEVTGLDLSQEMLEVAKKRAQSAKKIITFVQGNMLDLSQVGSF
                     DVVTCYSDSICYMQDEIEVGDVFKEVYQVLNDGGIFMFDVHSIYQMDHLFPGYSYHEN
                     AEEFAMVWDTYKAEAPHSVVHELTFFIQAEDGHFLRFDEVHEERTYDILTYDILLEQA
                     GFKSFKVYADFEDQEPTKTSKRWFFVAQK"
     gene            4767..5867
                     /locus_tag="TV193_000117"
     CDS             4767..5867
                     /locus_tag="TV193_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEL1512360.1"
                     /translation="MTVTGIIAEFNPFHYGHQYLLSQAKGLKIVAMSGNFVQRGEPAL
                     VDKWVRAQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIDTLAFGTEQLLD
                     YQKLSRLYSEQAEHMTAYLATLPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYV
                     KASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRA
                     PQVTWEHYFPFLKYHILTAPDLTQFFQVNDELASRISAAIRSVATVDELVEAVATKHY
                     TKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQ
                     LTQRADTVYQLGHTDMPEQTWGCVPIRPEAMN"
     gene            6223..6930
                     /locus_tag="TV193_000118"
     CDS             6223..6930
                     /locus_tag="TV193_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1512361.1"
                     /translation="MKTVKEVSQLTGLSVRTLHEIGLLPPTMVGENGYRFYDAAALRR
                     LQDILLFRELAFPLKTIKQLLDSPSYDQQAALAAQIKMLELRKAHLEKVIAHARTLQK
                     GEETMTFDIYSKSQLEAFQLEAKERWGETEAYMAYEAKVNQPSAEQLIKDMGEIFSIF
                     GRMLDQPVAELAVQQQVKALQDYISQHFYDCSTEILSALGCMYLEDDRFRAAIDHMGG
                     AGTAAFVSRAISYYCQH"
     gene            7071..7787
                     /locus_tag="TV193_000119"
     CDS             7071..7787
                     /locus_tag="TV193_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1512362.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDD
                     VEAEDGSITVYTAPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKL
                     VDALEADDDVQKVYHNVADV"
     gene            8009..8854
                     /locus_tag="TV193_000120"
     CDS             8009..8854
                     /locus_tag="TV193_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1512363.1"
                     /translation="MTIKRYLGLAGLAVLSVGMLAACGTKEKSASSTKDTPKEVIFAT
                     VGTTAPFSFEKEGQLTGYDIEVAKAVFKDAEKYKLQFKKTEWSSIFTGLDSGKYQMGG
                     NNISYTKERSVKYLFSYPIGATPSVLVVPKDSDIKSYDDIKGHSTQVVQGTTTAAQLK
                     AFNEEHADNPVELKFTNETITQMLTNLNEGKADFKIFDAPTVNAIIDNQGLDHLKTIE
                     LATSEQPFIYFIFSQDQEELQAFVNKRLEELTADGTLSKIAKKYLGGDYVPAKQDLKL
                     PTAKS"
     gene            9226..10071
                     /locus_tag="TV193_000121"
     CDS             9226..10071
                     /locus_tag="TV193_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1512364.1"
                     /translation="MNIKKAVGFVSLALASIALVACSGKQDDKNTLTIGVMTKTASDQ
                     ARWDKIEELLKKDKITLKYKEFTDYSQPNKAVANGEVDINSFQHYNFLDNWNKENKAD
                     LKAIAETYISPIHLFSGTSQDGKAKYQSVDELPDGAQIAVPNDATNESRALYVLQAAG
                     LIKLNVSGDKLATIANITENKKKLDIKELDASQTARALTSADAAIVNNSYAVPAKIDF
                     KTSLFKEKADENAKQWINIIAAQKDWEKSAKADAIKALIKAYHTDAVKKVVDKTSNGV
                     DVPVW"
     gene            10149..11519
                     /locus_tag="TV193_000122"
     CDS             10149..11519
                     /locus_tag="TV193_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEL1512365.1"
                     /translation="MTKTDQQYLTRLWEDQLTQDYLVSLGQLIASRSIFAQGIGLEET
                     AAYLKELFAQAGAEAIVDKTYAAPFVLARFNSSRPAAKTLIFYNHYDTVPADSDQKWT
                     SDPFTLTERDGYLFARGVDDDKGHIIARLTAVVRYLKEHADLPLNIVFMMEGAEESAS
                     VDLDRYLAKYADQLKGAELLIWEQGIRNEHDQLEITGGNKGILTFEMSVDSARCDIHF
                     KYGGVIESAAWYLLQALSSLRNHRGELLVPGIYQKVVPPTERELDLVETYAIENAQAL
                     KKLYGLELPMLQSERRQLLAAYYFQPSINIQGLWTGYQGQGVKTIIPSQATPKMEVRL
                     VPGLEPEYVFDQIRSYLLNKGFDQIKLTYTLGEMSYRSDLSSSAISQLIAAAQPFYPK
                     GLSLLPTSAGTGPMHTVFEALQVPIAAFGLGHSNSCDHAGDENIAIVDYCRHIALIEE
                     LITSYE"
     gene            11512..12576
                     /locus_tag="TV193_000123"
     CDS             11512..12576
                     /locus_tag="TV193_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEL1512366.1"
                     /translation="MSEPMIQLDHIDITFHQKKRVIEAVKDVTLHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQQPTKGSITIDGELTFDQGKVQLSANSLREKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSRLPKAERERKVTELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRRLGLTIVMITHEMQIVKDICH
                     RVAVMQQGTLIEEGSVLDIFSNPREPLTQEFIKTATGIDEALEKINQQDIVKELPANA
                     ILAQLKYAGTSTDEPLLNQIYRQFEVTANILYGNIEILDQVPVGEMIVVFEGAAASIE
                     AAEKALHEAGVDVTILKRGA"
     gene            12577..13269
                     /locus_tag="TV193_000124"
     CDS             12577..13269
                     /locus_tag="TV193_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1512367.1"
                     /translation="MLELFQAYLPNVYELGWSGDAGWGVAIWNTLYMTIVPFIVGGAI
                     GLFIGLLLVLMGPDGVIENRLVCWLLDKLTSIFRAIPFVILIAILASFTYLIMGTTLG
                     ATAALVPLTFATFPFFARQVQVVFSELDRGVIEAAQASGATFWDIVRVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATLIILLLIFAIQF
                     IGDSLTRHFSHK"
     gene            complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TV193_000125"
     CDS             complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TV193_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL1512368.1"
                     /translation="MKEKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGQNIPWSIIG
                     FCLTGVSLPLLGVIAVARSGSDDVESLARPISKWYAILYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDSIINKAIYAVLFFGLSYFLAIRPSKLAESIGKFLTPTLLVVITIL
                     IIASFVHPAGDYGEAFNAGAGINNAFKDVPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDQEITKITLISGAIAILLLAFVYIFVGRIGATSQSLFPFVDGHFTLNNSAV
                     NGGQILSHASRFYLGSIGQAFLAIVIFLACLTTSTGLITSSAEYFHKLMPRVSHVAWA
                     TLFTLVSAFFYFGGLSVIINWSSPILYLLYPLTVDLIVLVLIQKSFGNAPLVYRTTIG
                     LTIIPALYDALATLSQLTKLFTLPDGLSYFFERLVPLGQFSMGWISFSILGFVLGLII
                     SKTKGLHPTAS"
     gene            15127..16341
                     /gene="sstT"
                     /locus_tag="TV193_000126"
     CDS             15127..16341
                     /gene="sstT"
                     /locus_tag="TV193_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEL1512369.1"
                     /translation="MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLF
                     VGALKAIAPLLVFALVAQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPL
                     TLTLNTPVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKS
                     VPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLV
                     GTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDL
                     GLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISAC
                     GASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKQKKA"
     gene            complement(16695..17369)
                     /locus_tag="TV193_000127"
     CDS             complement(16695..17369)
                     /locus_tag="TV193_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEL1512370.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNYDQDVIAIDIRESHVKEIA
                     DLATKAAVGDITDKDFLIAVGVEQCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRHHIESIIYLEHGISMIEFTIPKSW
                     EGKSLSELDVRRKYELNIIGMRQKEVKTLDTNVQPFEPLEADTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(17379..18755)
                     /locus_tag="TV193_000128"
     CDS             complement(17379..18755)
                     /locus_tag="TV193_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEL1512371.1"
                     /translation="MKRSFFKSLSVTQRLTFSFAIVILIGSLLLSMPFTHYSNGPNTV
                     YLDHFFNVVSMVCVTGLSVVPVADVYNGIGQTIAMMLMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKKYLFFAYKVTFSLEAFAALVIMTDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKDFVLNPTINAIITFLIISGGLGFAVWVDLGTAF
                     KKYFFERPHCYGITFKKFSNQSRLVLQTTLVILVLGTFLSWFLEKDNLNTIARYNLPQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKITTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGYILLLSVEPDIAPIP
                     LLFESISAIATVGVSMDVTPHLSSAGRLIIIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(19278..19991)
                     /gene="rsmG"
                     /locus_tag="TV193_000129"
     CDS             complement(19278..19991)
                     /gene="rsmG"
                     /locus_tag="TV193_000129"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEL1512372.1"
                     /translation="MTPQAFYLVLEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAI
                     TEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDS
                     LNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELT
                     IPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKK
                     KETPNKYPRKAGIPNKKPL"
     gene            20127..20684
                     /locus_tag="TV193_000130"
     CDS             20127..20684
                     /locus_tag="TV193_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1512373.1"
                     /translation="MPMFLVIVALIGVLVVWLMVSYNGLVKARMHTKEAWSQIDVQLK
                     RRNDLIPNLVETVKGYANHEEKTLEKITSLRSRVADATTPQATMAASNELSKQVTSLF
                     AVAESYPDLKANSNFLKLQEELTNTENKISYSRQLFNTTTSHYNLKLESFPSNLVAKL
                     FGFKPSEFLQVPEAEKEVPKVDFTV"
     gene            20721..21614
                     /gene="htpX"
                     /locus_tag="TV193_000131"
     CDS             20721..21614
                     /gene="htpX"
                     /locus_tag="TV193_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEL1512374.1"
                     /translation="MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAA
                     FALIIGAIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPRVFI
                     IDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAV
                     ALASAVTLISSIGGRMMWYSGGRRRDNDRNDNGFGAIMLIFSILSLILAPLAASLVQL
                     AISRQREYLADASSVALTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEK
                     LSALFSTHPPIEDRIERLKHM"
     gene            21902..22435
                     /locus_tag="TV193_000132"
     CDS             21902..22435
                     /locus_tag="TV193_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEL1512375.1"
                     /translation="MLSVSDIRKRPEGIRFEREYDVKEALLIRDPQVIDINNVRASGR
                     AQFDDGLYLLEYQLGYQITLPSSRSMAPVVLDEMQTVQELFIEEADVASKQEMVDENL
                     VLVLSEDQLDLEESIIDNILLAIPLQVLTEAEKESQILPTGEDWAVLTEEQYQAQQKE
                     KAKDNSPFAGLQGLFDE"
     gene            22620..23306
                     /gene="covR"
                     /locus_tag="TV193_000133"
                     /gene_synonym="csrR"
     CDS             22620..23306
                     /gene="covR"
                     /locus_tag="TV193_000133"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEL1512376.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALE
                     KDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            23310..24800
                     /locus_tag="TV193_000134"
     CDS             23310..24800
                     /locus_tag="TV193_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HEL1512377.1"
                     /translation="MAKQKKYKKTLPKRLSNLLFVLFFCIFSAFTLLAYISTNYFLLK
                     REKQTIFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDRTHLKIDDANGSRIIRSERNI
                     TNTLNANEDIYVYNVDKQMIFTTDDEEASPGLNGTIGKVTKDHIEEQYKGFSMTQKVY
                     SNKTGKFVGYVQVFHDLENYYMIRARLFFWLLVVELFGVGLAYFIILIVTRNFLKPLN
                     NLHDVMRTISKNPDNLMLRSGISSGDEIEELSVIFDKMLDKIETHTRLQSRFISDVSH
                     ELRTPVAIIKGHIGLLQRWGKDDSAILDESLTAAAQEVDRMAIMINDMLDMIRVQGSF
                     EGHQNDTTVLESSIETVVGNFRVLREDFDFTWYSENQRTLAKIYKNHFEQALMILIDN
                     AVKYSRKEKKIVIELAVNASNEAVVKVKDRGEGISEEDIKHIFERFYRTDRSRNRTST
                     QAGLGIGLSILKQIVDGYHLHMEVESELNKGSVFILRIPLADHQGS"
     gene            24991..25485
                     /gene="nrdR"
                     /locus_tag="TV193_000135"
     CDS             24991..25485
                     /gene="nrdR"
                     /locus_tag="TV193_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEL1512378.1"
                     /translation="MRCPKCNYNKSSVVDSRQAEDGNTIRRRRECESCHTRFTTFERL
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENLISRIEQKVRTAYENE
                     VSSTVIGNLVMEELAELDEITYVRFASVYKSFKDLDEIEELLQQITNRVRGKKKSSVD
                     DEAY"
     gene            25469..26632
                     /locus_tag="TV193_000136"
     CDS             25469..26632
                     /locus_tag="TV193_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase loader"
                     /protein_id="HEL1512379.1"
                     /translation="MMKPIDTFSYIKHNQVQYDSSSLIQLYFPIIGNDAVAVYQYLVH
                     FFDDGSGAHKFSDILNHLQFGMKRLEEALVMLTAIDLLVLYQLPDAYLIKLHQPLGRE
                     AFLNNPIYRRLLEQKIGDVAVLELQMVIPNQARNISKTFSDVFGIDSQELKQPQPSKI
                     NFDLDSFQQLMRRDGLRFEDHQKDVISLYSISEQYHLTWFDTYQLAKATAVGGSIRPE
                     RMLVKKQQEGAQKTSESFSPAEQVVLRESKQDTPLVFLEKIKKARRARVTKDEKELLL
                     TLARMNFLDEVINIMVLYTFNKTKSANLHKTYLMKMANDFAYQRVLTAETAIIKTRAF
                     GERKQQAKSQQSNVPKWSNPDYQEKTSQEEQAKLEQFKQAALKRLENLGKSGD"
     gene            26633..27541
                     /gene="dnaI"
                     /locus_tag="TV193_000137"
     CDS             26633..27541
                     /gene="dnaI"
                     /locus_tag="TV193_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEL1512380.1"
                     /translation="MEKIGKMVEHLGQASRVASAELIEAILADQEVAEFIKAHQLSQA
                     EIKLSLSKFNQFLVERRKYQTGDETYIAKGYQPILVMNEGYADVSYLETRELVEAQRQ
                     AAIADRIHLVSLPRSYRRVSLSAVDVNNASRMQVFSELLDFVEQYPAAEQKGLYLYGD
                     MGVGKSYLMAAMAHELSEKKGVSTTLLHFPSFTIDVKNAISNGSVKEEIDAIKHVPVL
                     ILDDIGAEQATSWVRDEVLQVILQHRMLEDLPTFFTSNYSFADLERKWAKIKGNDETW
                     QAKRVMERVRYLARECHLEGVNRRQG"
     gene            27591..28901
                     /gene="der"
                     /locus_tag="TV193_000138"
     CDS             27591..28901
                     /gene="der"
                     /locus_tag="TV193_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEL1512381.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYT
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEGVTDADEY
                     VSKLLYRTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDSFPVSSVHGIGTGDVLDAII
                     DNLPIEEPVENDDVIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTSFT
                     DESGQAYTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDIVLMVINAEEGIRDYDK
                     RIAGFAHEAGKGMIIVVNKWDTIEKDNHTVARWEADIRDQFQFLTYAPIIFVSAVTKQ
                     RLNRLPELIKRISDSQSQRISSAILNDVIMDAIAINPTPTDKGRRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIKLIARNRK"
     gene            29242..32334
                     /locus_tag="TV193_000139"
     CDS             29242..32334
                     /locus_tag="TV193_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1512382.1"
                     /translation="MARLIPGRIRNQGIELYEQGLVKIIDDRTDLLRAEVDTYQVQYG
                     INDEDIRCQCDYFERKQYCQHIAALEYFLKNNQKGKSLSEQLNNQLESKEETKKLTSF
                     GSLFLDSLHMNEDDTTKYRLLASGAKSPFSSDYWWSLKINRLPGEKAYVIRDIKAFIH
                     LVKVEGFYQIGKNYFESLSILQFDQASQELIRFLWRLSTHSDKLDYEWLFPNHARHLR
                     LPAGFFEEGIDLLTGLYEFSFETSSQTYSHLYVRPLEAEAGLFQFTVDVHRSSIELYI
                     KEKNIEYFFNNEYLLYMNTFYHLSLKQQKMVQAIRSLPIEADLAKHIHFDLDDQAKLA
                     ASLLEFRELGQVKAPKSFDIRDFQVTFVFDITEKGELTSQLIFDYGSIQISDKASLDQ
                     LPFASHYKKESSIYRALKRFGLSPQFFAKKALTDPKDWYRFFTEAVPYFESLGRVQLS
                     SKLQDQRLMESPQLTVKREGGLLDISFDFSTVCQTDIEKALATLFSDRSYFVNQSGKL
                     VVFDEETQKISRSLQELRAKQLANGHLQLEGIAATQLSHLFSDLSSVHFSEELETLIK
                     DLQHPDRFELGELAVKAKVRDYQLQGIKWLSVLDKYGFGGILADDMGLGKTLQIIAFL
                     SSRLTETSKVLILAPSSLIYNWLDEFSKFAPQIDAAVSYGLKPARDALIQEGHQVTIT
                     SYSSFRQDLETYQANDYDYLILDEAQMIKNAQTKIAQSLRAFDVKNCFALSGTPIENK
                     LLEIWSIFQIVLPGLLPSKKAFLKMEARDVSRYIKPFVMRRKKEEVLPELPELIEMNY
                     YNEMSDGQKAIYLAQLRQMQERLSAATDDDINRSKLEILSGITRLRQICDTPSLFMDY
                     QGGSGKLDNLRTLLLQIKENGHRALLFSQFKGMLALVKQEMDQLGLSSYTITGSTPAN
                     DRQEMTRAFNNGSKDAFLISLKAGGVGLNLTGADTVILIDLWWNPAVEMQAISRAHRI
                     GQEDNVEVYRLITRGTIEEKILELQENKRHLITTVLDGKQGLASMSVEEIKEILGLQP
                     "
     gene            32538..33131
                     /locus_tag="TV193_000140"
     CDS             32538..33131
                     /locus_tag="TV193_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512383.1"
                     /translation="MTKHAFPLVADGEPIIESARQMALYENEDLITNIAGSYQDKHYD
                     DIIRDHQFAEKTPVVSKGSLHHSPVVDEDHSYAQKARRQAKQDVKEKRQAYIAKNMAY
                     SPKQASKKGQSGAFSSKKPATELSRFTEKLNQESYILAELPRQYKEPQNTSQAAVKKN
                     NYDFLKRSQIYNHQEDRDHREKTIAQELNLSRFEDIK"
     gene            33175..34506
                     /locus_tag="TV193_000141"
     CDS             33175..34506
                     /locus_tag="TV193_000141"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEL1512384.1"
                     /translation="MSKTYHFIGIKGSGMSALALLLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQ
                     FTSLGVAGAHGKTSTTGLLSHVLKHMTATSYLIGDGTGHGAADARYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPA
                     PIYYYGFEDTDDFVAFDITRTTNGSDFKVKHKGHAIGQFHVPAYGRHNILNATAVIAN
                     LFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYP
                     NKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREVDKGDVKVEDLAAR
                     VERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ"
     gene            34554..35036
                     /locus_tag="TV193_000142"
     CDS             34554..35036
                     /locus_tag="TV193_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1512385.1"
                     /translation="MLIRHVNQTDWEIIADIEQANFSPQEAVAANVIKERAELISDTF
                     LVAVIANQFVGYIEGPVIAEPRLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIG
                     TALLAAMKDLAVAQDRLGIILTCHDYLIPYYEMNGFQDQGLSASKHGGSVWYQMLWQP
                     "
     gene            35145..36719
                     /gene="mltG"
                     /locus_tag="TV193_000143"
     CDS             35145..36719
                     /gene="mltG"
                     /locus_tag="TV193_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEL1512386.1"
                     /translation="MALTDFKDDEQRRQQQKSFKEKILAELEKANQIRKEKEEELFKK
                     DLEVQEAARRTAQLYAEYKRQEALSNNPKQASDIAAASQETTSTASTAHTSAIKLEET
                     AVATGDQALSPPEEPALSESLLKEEASVEGQTKKGGPVRRKTSKRQQTDRMAKKISTV
                     LISSIVAIIVVIGLAGTAYVYSALNPVDKNSDDFVQVEIPAGSGNKLIGQILEKEGLI
                     KNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEDIAQALQEGGTAEPTKPVLGKILIPE
                     GYTIKQIAKAIETNSRAKNRSKAKTPFHSKDFLNLVTSDAFIQEMAKKYPKLLGDLPS
                     KEVATYQLEGYLFPATYNYYKETTLKDLAEEMIAAANANLAPYYEAIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNNGMALQSNIAILYAMGKLGEKTTLAEDAAI
                     DTTINSPYNVYINTGLMPGPVDSPGLAAIEATINPAATDYVYFVADVRTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            36792..37274
                     /gene="greA"
                     /locus_tag="TV193_000144"
     CDS             36792..37274
                     /gene="greA"
                     /locus_tag="TV193_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEL1512387.1"
                     /translation="MAEKTYPMTAAEKEQLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVVVQEVGTQT
                     TDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVKIESPAATYEVTIISVDKTQ
                     "
     gene            complement(37515..38435)
                     /gene="yidC"
                     /locus_tag="TV193_000145"
     CDS             complement(37515..38435)
                     /gene="yidC"
                     /locus_tag="TV193_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1512388.1"
                     /translation="MKLKTNRILFSGLALSVLLTLTGCVGRDAKGHPEGIIWDYLGKP
                     VSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQSEKMAYLKPFFEP
                     INQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVAVQFT
                     KGVSTSTFMGIDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLYTMPIMM
                     IVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPRLRKQIAEEFAKNPPKAYKSHQP
                     RKDVTAEKQALSTSKRTKLNRNAGKQKKRR"
     gene            complement(38518..38796)
                     /locus_tag="TV193_000146"
     CDS             complement(38518..38796)
                     /locus_tag="TV193_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEL1512389.1"
                     /translation="MKKVRLIVSGRVQGVGFRYSTYALALEIGDIYGRVWNNSDGTVE
                     ILAQASDPAKMTRFIQEIRKGPSKWAKVTYVDVNPSHFEDFHDFRISN"
     gene            39089..39826
                     /locus_tag="TV193_000147"
     CDS             39089..39826
                     /locus_tag="TV193_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEL1512390.1"
                     /translation="MIITSKANHLIKQAKKLLQKKHRKHSYLIEGWHLFEEAQRSGQE
                     LIHIFVLEEMAERLSGFDQVVIVSPEILKELTSSPNPQGIIAEVKLCQQALPTSYAGK
                     YLILEDIQDPGNLGTIIRTADAAKFDGVFLSEKSADVYNQKTLRSMQGSHFHLPIWRT
                     DIYQVSQVMQQQKIPVLATTLSQDSIDYKDLSARSSLALVLGNEGQGISPEMAALADQ
                     LIHISMPGQAESLNVAVAAGILIFSLI"
     gene            39865..40365
                     /locus_tag="TV193_000148"
     CDS             39865..40365
                     /locus_tag="TV193_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1512391.1"
                     /translation="MHYTEDTEYMEHVGHLIAHPRFQRLGDIVQHHHSTRLEHSVNVS
                     YSSYRLAKRLGLDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTAL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTFVDKYWAVKEAMTPLRQKWTNRRFLRRKT
                     LQSHNH"
     gene            40384..41073
                     /locus_tag="TV193_000149"
     CDS             40384..41073
                     /locus_tag="TV193_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEL1512392.1"
                     /translation="MNDNVIYTQSDAGLSHFFAKVYSLVGMGVGLSAFVSYLMLFPFR
                     QNLVSIVLDHPMVYYGAAIVELVLVFVASGAARRNTPAALPLFLVYSALNGFTLSFII
                     AAYAQTTVLQAFISSAAVFFAMSLLGVKVKRDLSGIRKAMFAALIGIIVASLVNLFIG
                     SDLMSYVISLISVLIFSGLIASDNQMIKQVYQASNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRLLGRND"
     gene            41467..41709
                     /locus_tag="TV193_000150"
     CDS             41467..41709
                     /locus_tag="TV193_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEL1512393.1"
                     /translation="MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK"
     gene            41889..42683
                     /gene="racE"
                     /locus_tag="TV193_000151"
     CDS             41889..42683
                     /gene="racE"
                     /locus_tag="TV193_000151"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEL1512394.1"
                     /translation="MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGP
                     RPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASA
                     AIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSV
                     AKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLL
                     NYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL"
     gene            42680..43669
                     /locus_tag="TV193_000152"
     CDS             42680..43669
                     /locus_tag="TV193_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEL1512395.1"
                     /translation="MSDNIYEYKDKDNWFIGKMTGHNLMAGWGVNHELIAKIDDMLGA
                     IAGDVDWESPVGYDVTVIRYASPFALISFVVGMINQKANRALKVVRHSGAILVTENER
                     LLAVHMPDDGVPVADFFGQQADGFGDTILIATRNEGKTKEFRRLFGDMGYRVENLNDY
                     PELPDVAETGVTFEENARLKAETISRLTGKMVLADDSGLKVDILGGLPGVWSARFSGP
                     DATDETNNAKLLHELAMVFDQKDRSAQFHTTLVVAAPGKDSLVVEADWHGYIATKPKG
                     EHGFGYDPLFIVGETGRHAAELAADEKNKLSHRGQAVKRLMEVFPAWQAKQSL"
     gene            43645..44166
                     /locus_tag="TV193_000153"
     CDS             43645..44166
                     /locus_tag="TV193_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEL1512396.1"
                     /translation="MASKTIIVMSDSHGDREVVAAIKGRYLGKVDAIFHNGDSELESS
                     DPIWEGIHVVAGNCDHDSGYKDSLVTSFDGLTIAQTHGHLYHINFTWDRLDYFAQETG
                     ADICLYGHLHRPAAWQLGKTVFINPGSVAQPRGEVNEKLYARVEWTAACIRVDYFTCQ
                     HKSYPSLSKEFKR"
     gene            44163..44624
                     /locus_tag="TV193_000154"
     CDS             44163..44624
                     /locus_tag="TV193_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1512397.1"
                     /translation="MIAKEFEAFLISHLDSYLIPAEELAIFINTHNADHVMLLLVSNG
                     FSRVPVITKEKQYVGTISISDIMTYQAKRQLTDWEMTQTNIGDMVNTKIETINITSSL
                     TEIMHKLVDFPFLPVVNDDNRFIGIITRKSILKAVNSLLHDFTDEYTITKK"
     gene            44621..45367
                     /gene="xerD"
                     /locus_tag="TV193_000155"
     CDS             44621..45367
                     /gene="xerD"
                     /locus_tag="TV193_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEL1512398.1"
                     /translation="MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLAL
                     YQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDT
                     SAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLS
                     KALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFIL
                     NEKAAGKSIIEVAQLLGLKSPITLEKYYKM"
     gene            45367..46074
                     /locus_tag="TV193_000156"
     CDS             45367..46074
                     /locus_tag="TV193_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEL1512399.1"
                     /translation="MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVEVIEQYLAYIET
                     LQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKAL
                     SQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHT
                     VIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVG
                     IEQTSHFGQIVLRKEIQ"
     gene            46071..46610
                     /locus_tag="TV193_000157"
     CDS             46071..46610
                     /locus_tag="TV193_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEL1512400.1"
                     /translation="MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQ
                     KYKEDKESGLCLIESSRTYKLVTKECLAPLLKDYAKAPINQTLSRASLEVLSIVAYKQ
                     PITRIEIDEIRGVNSSGALSKLVAFGLVQEAGKKEVIGRPNLYATTDYFLDYMGINHL
                     EELVDISSIAVEEQETTLF"
     gene            46847..47569
                     /locus_tag="TV193_000158"
     CDS             46847..47569
                     /locus_tag="TV193_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1512401.1"
                     /translation="MRINKYIAHAGLASRRKAEELIKRGLVTLNGQVITDLATTVKSG
                     DLVEVEGIPIYNEEKVYYLLNKPRGVISSVSDDKGRQTVIDLLPQVKERIYPVGRLDW
                     DTSGLLILTNDGDFTDKMIHPRNEIDKVYLARVKGVVTKESLRPLTRGVVIDGKKTKP
                     ARYRIIRVEPDKNRSIVELTIHEGRHHQVKKMFEVVGHLVDKLSRTQFGSLDVRGLKP
                     GEARRLSKKEVSQLHHLASTRK"
     gene            47566..47844
                     /gene="yidD"
                     /locus_tag="TV193_000159"
     CDS             47566..47844
                     /gene="yidD"
                     /locus_tag="TV193_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEL1512402.1"
                     /translation="MIKALLIAPVRAYQKYISPLFPPSCRYQPTCSAYMITAIEKHGA
                     KGVLMGLTRLLRCHPFAAGGEDPVPDTFSLKRHFITHEKIQDFDQKTD"
     gene            48003..48551
                     /locus_tag="TV193_000160"
     CDS             48003..48551
                     /locus_tag="TV193_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEL1512403.1"
                     /translation="MKQEIINRQYREKDSQNHVVLFQPQIPQNTGNIARTCAATNTPL
                     HIIRPMGFPIDDRKMKRAGLDYWDKLDIRFYDHLDEFLAQCDGSLHVISKFADRVYSD
                     EAYNDRQSHYFLFGREDTGLPEPFMRQYADRALRIPMNDEHVRSLNVSNAVCMIVYEA
                     LRQQAFKGLELSHTYEHDKLKS"
BASE COUNT        13967 a         9060 c        11513 g        14149 t
ORIGIN      
        1 gtttgctttg aaagaggaaa cctgctttcc cttctttttc atttgatttt gaatgctatt
       61 tctggtgaaa tatggtaaaa taaaaagtac taattatttt ggagatgaaa tgagtgtcga
      121 tgattatagg ccgacctatg cggtagaggc tgtttatgat ttaagagcaa atgatttact
      181 gcgtcaaggt attacagctg tcttggtgga tttagataat accttaatcg cctgggataa
      241 tcctgatgga actccggagg ttcgtgcttg gttagatgag atgacgattg cagatattag
      301 tgtggtggtt gtgtcaaata acacgtattc acgtgtggag cgtgctgttt cgcggtttgg
      361 tgtggatttt attgctcgtg cgatgaagcc ttttgcctat ggtattaata aggctattga
      421 tcgttatggc tttgatcgtg atgaggttat tatggttggg gatcagctaa tgactgatat
      481 tagagctagt catcgggcag ggattaagtc tgtcttagtg aagcccttag taacatcaga
      541 tgcttggaac actaaggtta atagatggcg tgagcgtcgt gttttggcaa aattggaaga
      601 aaaatatgga aggctagtat atcaaaaagg gatttaatgg aagaattatt ttgtatcggc
      661 tgcggtatcc agattcaaac aacaagaaag caagaggctg gctttacacc tgctgctgct
      721 ttggtaaagg gaattgaagc tagggagatt tactgtcaac gctgctttag attacgtcac
      781 tacaacgaca ttacagatgt tcatattact gatgaagagt ttttgaggct gctccatgag
      841 gtgggagata gtgatgcctt ggtcgttaat gtgattgaca tttttgattt taatggctca
      901 gttattccag gcttatcacg ctttgttgct ggaaatgatg tgttattagt tgggaataaa
      961 aaggatattc ttccgaagtc tgttaaggac agcaaggtga cacagtggtt gacagaaaga
     1021 gctcatgagg agggcttgag acctcttgat gtcctgctga cgagtgcgca gaataaatat
     1081 gctattaaag agctgattga gcggatcgat caattgcgcc aagggcgaga tgtctatgtt
     1141 gttggggtga ctaatgttgg aaagtcgacc ttgattaatg ccattattca ggaaattact
     1201 ggggataagg atgtgattac aacgtcacgc tttcctggga ccactcttga taaaatcgaa
     1261 attcctttag atgatggtag ctttatcttt gatactcctg gtattatcca tcgtcaccag
     1321 atggctcact atttgtcagc taagaatttg aagtttatca gccctaagaa ggaaattaag
     1381 cctaaaacct accaattaaa tccggagcaa acgctttttt taggtggctt ggcgcgattt
     1441 gattttatta gtggtgaaag acaaggcttt acagcttatt ttgataatca attgctcctc
     1501 catcggacaa aattagaggg tgcagatgct ttttatgaca agcaggcagg gcaactgctg
     1561 actcctcctg ataaaaagga gcttgatgat tttcctaggt tggttcgtca tgaatttctg
     1621 ctggatcaaa aagtggacgt tgttttttct ggtcttggtt ggattcgtgt taatgctaat
     1681 aaggaaactg caactaaggt ggcggcttgg gctcctgatg gtgttgcagt agtcgttcgc
     1741 aaggcgatta tttaataaat aaaaagaaaa gtggaataaa aatgcttaca agtaaacaaa
     1801 gagccttttt aaaggctgag gcccatagtc ttaaaccgat tgttcagatt ggtaaaaatg
     1861 gcttgaatga tcagattaaa accagtattc gtcaagcctt ggacgctaga gagctgatca
     1921 aggttactct gttgcaaaat actgatgaaa cgattcatga ggtggcagag attttagaag
     1981 aggagattgg ctgtgatacg gttttaaaga ttggtcggat ccttattttg tttaaggtgt
     2041 cagctaaaaa agacaatatt ttgtttaagg tgtcagctaa aaaagacaat cgcaagctat
     2101 cagttaaggt caaatcgatc tagcgagagc ttttgctagg ctaagacgtt taggtctgct
     2161 gtgtcagtgc tgacaacatg agtaatggtg atattttgga gaggttatgg ctttagaact
     2221 tttgacgcct tttacgaggg tggaattaga aatggaaaaa aaagatagca atcgcaagca
     2281 ggttggtatc ttgggaggga attttaatcc tgttcataat gctcatttag tggtggctga
     2341 ccaggttcgt caacaattgg ggcttgatca ggtgcttttg atgcctgagt ttaagcctcc
     2401 gcatgttgac cacaaagaaa caattgatga aaaacatagg cttcgtatgc tggagctggc
     2461 tattcaggag acagaaggtc tagcgattga agagattgag cttacacgtc aaggggttag
     2521 ctatacctat gatacgatga agctgttaat tgagcaaaat cctgacgtgg attattattt
     2581 cattattggt gcggatatgg tagattattt gccaaagtgg caccgtattg atgagttgat
     2641 ccatatggtg cagtttgtcg gcgtgcaaag gcctaaatac aaggctggta cctcttatcc
     2701 ggttatctgg gtagatgttc ccttgctaga tatttcctca agcatgattc gtgactttat
     2761 ccaaagtgat cgtcagccta atcatttatt accaaaggct gttttagact atattcataa
     2821 agaaggcctg tatcaatgat gtatcaagat tatgttggct atagacgtga tgagctgtta
     2881 ggaaaaattg ctgagcagat gagcgataag cgctttaagc atgttcttgg cgtggaaagg
     2941 gctgctattc acttggcaga gcgttaccat tgtgatccga ttaaggctgg gttagcagct
     3001 ctactgcatg actatgccaa ggaatgtcct gatgagcttt ttataagctt aattgacaaa
     3061 tatcagctgg atcctgagct tcttaaatgg aacaataata tttggcatgg tatggttggc
     3121 atttataagc ttcaggaaga tttggggtta aaagacaaag gcattttgcg ggcaattgag
     3181 attcatactg ttggcgctgc tgagatgacg atattggata aaattctgta cgttgcagat
     3241 tatattgagg aaggtcgagt gtttcctttg gtggacgaag ctaggagaat agcagagctt
     3301 gatctagata aggcagttgc ctacgaaaca gctcatacag ttgcttattt ggcatcgaag
     3361 gctcagccga tttttccgca aaccattgat acttacaatg cctttgtgca ttatttacat
     3421 gaggaataaa atgagaaaag aagaactttt agaaattgtg attaaggctg ctgatgaaaa
     3481 gcgtgctgag gatatgctag ctcttgatct ggctggctta acaagcctaa cggactattt
     3541 tgttattgta acggcaacca atagtcgtca gttggaggcg attgctgaca atattcgtga
     3601 aagggttaag gaagcaagtg gtgatgctag tcatgttgaa ggaaacagtc agactggttg
     3661 ggtgctgctg gatttgaatg atgtggtcgt gcatatcttc tcagaagatg agcgttatca
     3721 ttataatctt gaaaagcttt ggcatgaggc tccagctgtg gagcttagcc actatttagg
     3781 ataaaaaagc agtcggctct gggctgtttt ttacaataag aaacagaaag gaagttggca
     3841 ttagaggcag gattgcctaa gaggtaagct cttgtagtac ttgctgtgag acgtgttgac
     3901 tgtatcaaat aatatgcaaa agaattatga taccttcgca tcagtttatg atgccattat
     3961 ggacgactca ctttatgata agtggacagc gttttcgctt cgtcatttac ctaaaaacaa
     4021 ggagcatcag aagcttttgg agctggcctg tgggactggt attcaatcgg ttcgatttgc
     4081 tcagtcaggc tttgaggtta ctggcttgga tcttagtcag gaaatgctag aggttgctaa
     4141 aaagcgagct caatcagcta agaagatcat tacctttgtg caaggtaata tgctggatct
     4201 gtcacaggtt ggatcgtttg atgtggtgac ctgctattcg gattcgattt gttatatgca
     4261 ggacgagatt gaggtgggtg atgtctttaa agaggtctat caggttttga atgatggcgg
     4321 tatttttatg tttgatgttc attctattta tcagatggat cacctttttc ctggttattc
     4381 ttaccatgaa aatgctgagg aatttgctat ggtttgggat acctacaagg ctgaggctcc
     4441 acattcagtg gtgcatgagc tgaccttttt tattcaggct gaggacggcc attttttacg
     4501 ctttgatgag gtacatgagg agcgtaccta tgatatcttg acctacgata ttttgctgga
     4561 gcaggctggc tttaagtctt tcaaggttta tgcagatttt gaggatcagg agccaacaaa
     4621 gacaagtaag cgctggtttt ttgttgcaca aaaatagctg tggctaagac aggtcagcga
     4681 gcggttttgt ggtttagtgg ctctgtattg agtctgtggc aggtcttgat gataatagga
     4741 atagatgcga aaggtaggac aatgttatga ctgtcactgg tattattgct gaatttaacc
     4801 cttttcatta tgggcatcag tacttactat cacaggcaaa ggggctaaaa attgttgcga
     4861 tgtcggggaa ttttgtgcag cgaggggagc cggcacttgt ggataagtgg gtacgcgcgc
     4921 aaatggcatt ggaaaatgga gctgaccttg tggttgagct cccttttctg gtttctgttc
     4981 aatctgcaga ttattttgct cagggagctg tggatatctt gatgagactt ggaattgata
     5041 cccttgcctt tgggactgag caattgcttg attaccagaa gctgtctagg ctatatagtg
     5101 aacaagcaga gcacatgact gcttatttgg ccaccttacc tgatcatcta tcttatccac
     5161 aaaaaacaca aagcatgtgg gaggcctttg caggccttag cgctactggt gataggccaa
     5221 accatctttt agcattatcc tatgtcaagg ccagcgcagg aaaaaagctg caattgcagc
     5281 cgattaagcg gctgggggca ggctttcatt cagaagccaa ggatcaatgc ttgtcatcgg
     5341 cgacagcaat tcgaaagcat atcgctgaca gagcctttgt ggaaaaatca tcacctaatg
     5401 cagctcttat tttgagggct cctcaggtga cttgggagca ttattttccc tttttaaaat
     5461 atcacattct gacagctcca gatttaacac agttttttca ggttaatgat gagctagcta
     5521 gtagaatcag cgcagctatt cggagtgtag cgacggtaga tgagctagta gaggcggttg
     5581 caaccaagca ctataccaag gcaagggtga ggcgtgtgtt gacctatatc ttggttaagg
     5641 ctgtggaagc cccattgcca gaaggcatac atgttttggg cttttcaaaa aaaggtcagg
     5701 ctcaccttaa aacaataaaa gcttctgtgc cgctaatcag tcgtattgga gctaagcctt
     5761 gggatcagtt gactcaacga gctgacactg tttatcagct gggacatacg gatatgccag
     5821 agcagacttg gggatgtgtg ccgataaggc cagaggcgat gaattgagcg ttactagaag
     5881 caaaccactg tctttgtatg acacgcttag aggaccagca agagcttcta agaagttcgg
     5941 gtaggcccta tagtcagttg gtaaaggtgt tattagagta gttcaggtga ctctttgctg
     6001 gtataaaggt cagatagact gcctttgctt gctaagctgt ttttcattgc tgataagaag
     6061 gatagttagc aagaactgtc agctcatgga agcttatcat ttaagatcaa aaaagttaag
     6121 tttgttcttg actctctccc tacgtgatag tctatacttg ttgttgaggt ggaaatagcc
     6181 atactagttg gtgctctttt gacctcacta aggaggaata ccatgaaaac cgtaaaagag
     6241 gttagtcaat tgacagggct tagtgtacgc accttgcatg agataggcct gctgcctcct
     6301 acaatggtgg gagaaaatgg ttatcgcttt tatgatgctg ctgccttgag acgtctacag
     6361 gacatcttac tgtttcgtga gctggcattt cctctaaaaa cgattaaaca attgctggac
     6421 agccctagct atgaccaaca agcagccctt gctgctcaga ttaagatgct agagctacgc
     6481 aaggctcatt tagaaaaggt tattgctcat gctaggactt tacaaaaagg agaagaaacc
     6541 atgacctttg acatttatag taagtcacag ctagaagcct ttcaactaga ggctaaggag
     6601 cgttggggag agacagaggc ctatatggct tatgaggcca aagtcaatca gcctagcgca
     6661 gagcagctta tcaaggatat gggggagatc ttttcaatct ttggtcgtat gctggatcag
     6721 cctgtagcag agctagcagt acagcagcag gtaaaggctc tgcaggatta cattagtcaa
     6781 cacttttacg attgctcaac tgagatctta tcagctcttg gttgtatgta tcttgaggat
     6841 gaccgcttta gagcagctat tgatcatatg ggtggtgcag gaacggcagc ctttgtcagc
     6901 cgagctatta gctattattg tcagcactaa gctgctaagt gcatatcact ggctgctatt
     6961 cctaatttac gaaccctttt gaaagtgcta taatgataga gttaaagcta atttaactct
     7021 gcttattcta aaaagagctt aatcaaaatt gtattttaga ggagaatcca atgggacgta
     7081 aatgggcaaa tattgttgca aaaaaaactg ctaaagacgg tgcaacatca aaggtttatg
     7141 ctaagtttgg tgttgaaatc tatgtggctg ctaagcaagg agagcctgat cctgagttga
     7201 atacagccct caagtttgtc attgatcggg caaagcaggc acaggtgcca aagcatgtta
     7261 ttgataaagc cattgataag gcaaagggta atactgatga gacctttgtt gagggacgct
     7321 atgagggctt tggaccaaat gggtcaatga ttatcgtaga caccttgacg tcaaatgtga
     7381 accgtacagc tgccaatgtt cgtgctgcct atggtaaaaa tggtggtaat atgggagcgg
     7441 ctggatcagt ttcttactta tttgataaaa agggggttat cgtttttaag ggcgatgacg
     7501 cagacagtat ttttgagttg ctcctagagg ctgatgttga tgttgatgat gtagaggcag
     7561 aagacggatc aattactgtt tatacagcac caacagatct gcataaggct attcttgctc
     7621 ttcgtgaatc aggtatatca gagtttcagg tgactgagct tgagatgatt cctcagtctg
     7681 aggtaactct tgagggggat gaccttgctg tttttgaaaa gctggttgat gcccttgaag
     7741 cagatgatga tgtgcaaaag gtctatcata atgtagctga tgtctaagcc ctaagactat
     7801 catgtaaaca gagccgagat ttctcggctc tgttcatttt cctataatcg agctctgtag
     7861 aggctgagta tgactatctg ccttttatgg taacagctga cgtagtagct gatcgtcaca
     7921 tggtgctgct ttagcagagt tcaatcatta gtatcttatg ataaaaaatg ataaactaat
     7981 cttatgaatc ataaaggagt agaggacaat gacaataaaa cgttatttag gtttagctgg
     8041 cttggccgta ctgtctgtgg gtatgctagc ggcatgtggc acaaaggaaa aatcagcttc
     8101 gagcacaaag gacacaccaa aagaggttat ctttgcgaca gttggaacaa ctgccccctt
     8161 ctcatttgaa aaggaaggac aattgacagg ctatgacatc gaagtggcta aggctgtgtt
     8221 taaagatgct gagaagtaca agcttcaatt taagaaaaca gaatggtcat ctatttttac
     8281 gggcttagac tctggaaaat atcaaatggg cggcaacaat atttcataca ctaaggaacg
     8341 ctcagtcaaa tatttgtttt cttatccaat tggtgcaact ccgtcagtgc tagttgtgcc
     8401 aaaggatagt gatatcaagt cttatgatga tattaagggt cattcaacac aggtggtgca
     8461 gggaacaacg actgctgctc agctaaaggc cttcaacgaa gagcatgctg ataatcctgt
     8521 tgagctaaag tttaccaacg aaaccatcac tcaaatgcta accaatctga atgagggcaa
     8581 ggctgatttt aagatttttg atgccccaac ggttaatgct atcattgata atcaaggctt
     8641 agatcacttg aaaacaattg agctggcaac aagcgagcag ccctttatct actttatttt
     8701 tagtcaagat caagaggagc tacaggcctt tgtcaataag cgcttagagg agctgacagc
     8761 tgatggcaca ctcagtaaaa ttgctaaaaa gtatctaggt ggcgattatg ttccagctaa
     8821 gcaggatttg aagcttccta cagcaaaatc ctaaattggc tgaaagacca acaacgatat
     8881 aagcgactat ttggcttaaa accaagctgt tagaaggctt gcttttaagc ctttttaaat
     8941 gcctttgttg cctactaggg cttttaaagt aacctagtgt ctagggcagc agctattaag
     9001 atctgttgcc ttatttcgag ggtggttttg aggtaaaagg tctgtagtaa gagccttgac
     9061 ttaattaatg cttgcttggc tagtctgtca gttggtttag gtttggtgtt ttgactagag
     9121 attatagcta atggctatac cttatcctaa aatttaccaa tttgaatgcg agagctattt
     9181 cgtataaaat aaactcattg aaaaaaagaa attgaggaac aaaatatgaa tattaaaaaa
     9241 gctgtcggct ttgttagcct tgctcttgct tcaatagctc tagtagcctg ctctggtaag
     9301 caggacgaca aaaatacctt gaccattggg gtaatgacta aaacggcatc tgatcaagcc
     9361 agatgggata agattgaaga gctgctgaaa aaggataaga tcactctaaa gtataaagag
     9421 ttcacagatt attctcagcc caacaaggca gttgctaatg gtgaggttga tatcaattca
     9481 ttccagcact ataacttttt ggataattgg aataaggaaa ataaggcaga tttgaaggct
     9541 attgctgaaa cctatatcag tccgattcat ctcttttcag ggactagtca agacggtaag
     9601 gctaaatacc agtcagtaga tgagcttcca gatggtgcgc aaattgcagt gccaaacgat
     9661 gcaacaaatg aaagccgtgc cctgtatgtg cttcaagcag ccggcttgat caagctcaat
     9721 gtgtcaggtg ataagctggc aaccattgca aatattacag aaaataagaa aaagctagat
     9781 attaaagaat tagatgcgag tcagacagca cgtgccttga cgtcagctga tgccgctatt
     9841 gttaataata gctatgccgt tcctgcgaaa attgatttta aaacctctct ttttaaggaa
     9901 aaggctgatg agaatgccaa gcaatggatt aatatcattg ctgctcaaaa ggattgggaa
     9961 aagtctgcta aggcagacgc gattaaggca ttaatcaagg cctaccatac agatgctgtg
    10021 aagaaggttg tggataaaac ctcaaatggt gttgacgtcc ctgtatggta agggataata
    10081 ggtaatatta gtaacaggag gattgaggcg tgtgaagcac gccctttctt atattagggg
    10141 gaaaacacat gacaaaaacg gatcagcagt acttaacaag gctttgggag gatcagctca
    10201 cacaggatta tcttgtgtcg ttggggcaat tgattgccag taggtctatt tttgctcaag
    10261 gtatcggctt agaagagaca gcagcctacc taaaggagct gtttgctcag gctggtgctg
    10321 aggctattgt tgataagact tatgcagctc cctttgtcct agcacgcttt aatagctcta
    10381 ggccagctgc taagacactg atattttaca atcattacga tacagtgcca gcagatagtg
    10441 atcaaaagtg gacgagtgat ccctttacct taacagagcg tgatggctat ttgtttgcgc
    10501 gcggcgttga tgatgacaag gggcatatca ttgcgagatt gacggctgtc gtcaggtatc
    10561 taaaggagca tgcagacctt ccgcttaata ttgtctttat gatggaggga gctgaggagt
    10621 cagcttcggt agatttagat cggtatctgg ctaaatacgc agaccagcta aagggagcag
    10681 agcttttgat ttgggagcag ggcattcgta atgagcatga tcagcttgaa ataactggcg
    10741 gcaataaggg gattttgacc tttgagatgt cagtagatag tgctcgttgt gatattcatt
    10801 ttaaatatgg tggtgttatc gagtcagcag cctggtattt gcttcaggcc ctatcaagcc
    10861 tgcggaacca tcgtggggaa ttgctggtgc ctggtattta tcaaaaagtc gttccgccaa
    10921 ctgagcgaga gctagattta gttgagacct atgcaattga gaatgctcaa gctctaaaaa
    10981 agctttacgg actggagctt cctatgttac aatcagagcg tcgtcaattg ttagcagctt
    11041 attactttca gccctccatt aacattcaag ggctgtggac tggctatcaa ggacaaggag
    11101 ttaagaccat cattccttca caggctactc ctaaaatgga ggttcgtttg gttcctggct
    11161 tagagcctga gtatgtcttt gatcagatta ggtcttattt gctcaataag ggctttgacc
    11221 agatcaagct gacctatact ttgggtgaga tgagctatcg gagtgatctt tcatcgtctg
    11281 ctattagtca gctgattgca gcagctcagc ctttttaccc taaggggcta tctcttttgc
    11341 cgacatcggc aggaacaggc cctatgcata ctgtttttga agccctgcag gttccgattg
    11401 ccgcttttgg cttagggcat tctaatagtt gtgatcatgc aggtgatgaa aacattgcta
    11461 ttgtagatta ttgtcggcat attgcattaa tagaggagtt aataacatct tatgagtgaa
    11521 ccaatgattc aattagatca tattgatatt acctttcacc aaaaaaaacg tgtgattgaa
    11581 gctgttaagg atgtaacgct tcatatcaac caaggggata tttatggcat tgttggctat
    11641 tctggtgctg gcaaatcaac cctagtgcgt gtgattaacc tgctgcagca gccaacaaag
    11701 ggaagcatta caattgatgg ggagctgacc tttgatcaag gcaaggttca gctgtctgct
    11761 aatagcctac gtgagaagcg tcgtgatatt ggcatgattt ttcagcattt caatcttatg
    11821 gcacaaaaaa cagctaagga aaatgttgcc tttgctctgc gccattctcg attgcctaag
    11881 gctgaaagag aaaggaaggt gactgagcta ttagaattag taggcttatc tgagcgtgca
    11941 gacaattatc cagcacagct gtctggtggt caaaagcaga gggttgctat tgcgcgtgcc
    12001 cttgccaatg accctaaaat attgatttct gacgaggcca cctcagcgct agatcctaaa
    12061 acgaccaagc agattctcgc tcttttgcag gaattaaacc gcaggctagg cttaacgatt
    12121 gtcatgatta cgcatgaaat gcagattgtc aaggatattt gtcatcgtgt ggctgttatg
    12181 cagcagggaa ccttgattga agaaggcagt gttttggata tcttctcaaa tccaagagag
    12241 cctttgacgc aggagtttat caagacagcg actgggattg atgaggcact tgagaaaatt
    12301 aaccagcagg atattgtcaa ggagctacca gctaatgcta ttttagctca gctcaagtat
    12361 gcagggacat cgactgacga gcctttactt aaccagattt atcgccagtt tgaggtgacc
    12421 gctaacattc tttatgggaa tattgaaatc ttagatcagg taccagttgg tgagatgatt
    12481 gttgtttttg aaggtgcagc agcaagtatt gaggcggcag aaaaagcctt gcatgaggct
    12541 ggcgtcgatg tcactatttt aaagagaggg gcttaaatgt tagaattgtt tcaggcttat
    12601 ttgccaaatg tttatgagct tggctggtct ggtgatgctg gctggggagt agccatttgg
    12661 aataccttgt acatgacgat cgttccattt attgtaggtg gagctattgg tttatttatt
    12721 ggtcttttgc tggtactgat ggggccagat ggggtgattg aaaatcgact ggtttgttgg
    12781 cttctagata agctcacgtc gatttttcgg gctattccct ttgttatatt aattgctatc
    12841 ctggcaagct ttacttatct gattatgggg acaaccttgg gtgcaaccgc agctctggtg
    12901 cctttgacct ttgcaacctt tccttttttt gcgcgtcagg tccaggttgt tttttcagag
    12961 cttgatagag gtgtgattga ggctgcacag gcttcaggag ctaccttctg ggatattgtc
    13021 agggtttatc tgagtgaggg cttaccagac ctgattcgtg tgtcaacagt gaccttgatt
    13081 tccttggttg gtgagacagc gatggcagga gctattggtg ctggagggct tggtaatgtc
    13141 gcgatttcct atggctataa ccgttttaac aatgatgtga cgtgggttgc cacccttatt
    13201 attctcttgc tgatctttgc gattcaattt attggagaca gcctgacaag gcattttagt
    13261 cacaaataat aaaactgctc agagctttat tagctccaag cagtttttta atgtcatgat
    13321 gctgtagggt gaagtccttt tgtcttgctg atgatgagac ctaagacaaa gcctaggatg
    13381 gaaaagctaa tccagcccat tgaaaattgg ccgagtggaa ccaacctttc aaagaaatag
    13441 gaaagaccat caggcaaggt aaagagcttg gttagctgtg agagggtagc tagggcgtca
    13501 tacaatgctg gaatgatggt aaggccaatc gtcgttctgt agacaagagg ggcattgcca
    13561 aatgactttt ggatcagaac aagaacaatc aaatcgacag tcagtgggta caagaggtac
    13621 aaaataggag atgaccaatt gataataact gacaagccac cgaagtagaa aaaggcagat
    13681 acaagggtaa atagagttgc ccaagcaaca tgtgataccc ttggcattag cttgtggaaa
    13741 tactctgcac ttgaggtgat aagaccggtt gaggtggtca gacaggctag gaaaatcaca
    13801 atcgcaagga aggcttgccc aatgctacct aggtaaaatc gtgaggcgtg gcttaaaatt
    13861 tgtcctccat tgacagcgct gttgtttagg gtaaaatgcc catcaacaaa agggaaaaga
    13921 gattgtgagg tcgcaccgat ccgtcccaca aaaatataaa caaaggctag cagcaaaatg
    13981 gcaatggccc cagagataag ggtgatttta gtgatttcct gatcggtttt agcgccaaat
    14041 tgcttggttg cttcaatgac taatatggca aaaaccaagg aagctaaagc atccatagtg
    14101 ccgtagcctt gaataagacc tgcaataaag ggaacgtcct taaaggcatt gttgatacct
    14161 gctccagcat taaaggcttc gccatagtct ccagctgggt gaacaaagga ggcaatgatt
    14221 aaaatagtaa tcacaaccaa tagcgtcggt gtcagaaatt taccaatgct ttctgctagc
    14281 ttgcttggtc taatagccaa aaagtaggat aagccaaaaa atagcacagc atagatggct
    14341 ttattgatga tgctatctcc taatatcggg gcaatcccaa cagagaagga ggtagcgcct
    14401 gttctaggaa tagcaaagaa aggaccaatg gacaaataca ggattgatga gtaaaggata
    14461 gcataccatt ttgaaattgg ccgagccagg ctttcaacat catcagagcc tgaccttgca
    14521 acagcaatga caccaagcaa gggtaaagac acaccagtca agcaaaagcc aataatggac
    14581 caagggatat tttgtcctga atagatgcca agaaaggccg gataaatgag atttgctgca
    14641 ccaaaaaaga gagcaaacag cataaagcca ataacgatat agacattttt ttctttcatt
    14701 gccttaataa gtctttcttt tgatataaat ttgaagattc caataattta attgaaaact
    14761 cttgaaaata ataacagttg ctattatacc taagtttctg aaagtcgtca acaattatca
    14821 gacgatagat caagctgaga cctaaaaaag cgctgagggg tatctggata aagcagctta
    14881 gcctttattt tacagctttt gagaggactt gctcacctgc tgaatctcta atcaagcctt
    14941 gctagaaaga gtggtccaag gcttggggag ctttgatgag agatttgctg tcttattgat
    15001 gaaagaatct gtcagctagc ttatgatggt ggggctgcag cggtgtataa catccttgct
    15061 tgatttgacg aataactaaa attatattat gataaaaaac atctaacttg agcgaggata
    15121 aataacatga aaagaattcg tgacttatgg gtcaggacca acctgattaa aaaaatagga
    15181 atcggggtcg ttataggact tcttttgggg attttattgc ctgatgtgac agcgattggc
    15241 attttggggc agctttttgt tggggcttta aaggcgatag ctcctctctt ggtttttgcc
    15301 ttggtggcac aagctatctc tcaccaaagg tcaggacagc aaaccaatat gaccttgatt
    15361 attgtgcttt atttgcttgg aacctttctg gcggccttgg ttgctgttat tgctaattac
    15421 ctatttcctc taaccttaac cttaaatact ccggttaata ctgagctttc accaccacaa
    15481 ggtattgttc aggtctttca gacgctttta ttaaagctag tggataatcc tattaatgct
    15541 ttagctactg ccaattatat tggtgtctta gcttgggcat tgatctttgg cttagccctc
    15601 aagtctgttc cttcagattt taagcatttg atcaaaacag cggcagatgt gacctcacaa
    15661 attgtcgttt ggattatcaa tgtcgcaccg attggcatta tgggcttggt cttttcaact
    15721 gtttctgaaa atggcattag cattttgtct gattatgctc ttttaattct ggtcttggtg
    15781 ggaacgatgc tctttgtagc gctagtggtt aaccctttgc ttgcctttgt cctgactcat
    15841 caaaatcctt atcctcttgt ttttagatgt ttaaaggatt ctggccttac agcctttttc
    15901 acaagaagct cggcagcaaa cattccagtc aatttgcagc tatgtgagga cttgggacta
    15961 agtcaggcga cctatttagt atctattccc ctaggtgcaa tgattaatat gggaggagca
    16021 gccatcacga tcaatgtttt gacacttgct gctgtcaata cctttggtat tcagattgat
    16081 tttctgactg ccctgctttt gagtgtggtt gcggctatct cagcctgtgg cgcttctggt
    16141 gttacaggag gctctctcct tcttattcca gtggcatgta gcctttttgg gatctcaagt
    16201 gatttggcta tgcaggttgt cggggttggc tttattgttg gtgtgattca ggattcctgt
    16261 gaaacagccc ttaattcatc aactgatgtc ctctttacag ccattgctga aaatgccttc
    16321 tggaagcaaa agaaggccta gccttataat acagcttatt agtaaaaaaa gaggctggga
    16381 caaaaagagc tgcactttag aaagtcttaa cctaatatac tttatgacct agtctcatgc
    16441 attaaaaaag cgaacaagtc tagttttcgg aatctctgaa aactggctcc atgtcaactg
    16501 tagtgggtga cttatagcta agcacgagag gagacgaagg ttgtcttctc ttttgtgatg
    16561 ttcaaagcga ggaagatgcg ttttttaggc tctataatct ccacagtggc cttacccact
    16621 acagaaatta tagagcctga aaactagact tgttcgttta ttttaggtca gacttttgtc
    16681 ccagacccgt tatgttattt gaggtagcct aggtagtcaa acttttcaaa ggtatgatcg
    16741 ttagcgatag caacaataat ggtgtcagcc tcaagtggtt caaagggctg aacattggtg
    16801 tctagggttt tgacctcttt ttgacgcatg ccaataatat taagctcgta ttttcgacga
    16861 acatcaagct ctgagagcga tttgccctcc cagctcttag gaatggtgaa ttcgatcatg
    16921 gaaatcccat gttctaggta gataatgctc tcaatgtgat ggcgtaagag atttgaggcc
    16981 actcgctttc cagagtctct ttcaggggtg ataaccttgg ttgctccaat gccatataag
    17041 acctcttcaa aaattttgtt tttagccttt gcaataatgg ttggaacccc taatttttta
    17101 cagtgcatga cagctagtac agaggactct agattgtttc ctgatgcgat gacaactgtg
    17161 tcacattgct caacccctac tgcgattaaa aaatccttat cagtaatatc gccaacagct
    17221 gccttggtcg ccaaatcagc aatttctttc acgtggcttt ctctaatatc aatggcaatg
    17281 acatcttggt catagttgct taattctctg gcaacggtgc ggccaaaaat ccccaggcca
    17341 agaacaccaa cagtttttcg ttttaacatg atttctcctt aacccactaa aatatcagta
    17401 gtggcatatt gaatggtttt ttctttacgt tgaattagac taatcaaaac agtaattggt
    17461 ccgacacgac caacaaacat cagcacaata atgattaggc gtcctgcact tgataagtgc
    17521 ggtgtgacgt ccattgatac cccaaccgtt gcaatagctg aaatggattc aaataaaagc
    17581 ggaatagggg cgatatctgg ctctacactt agcagtaaaa tgtagccaat catcaagacc
    17641 gcaaaaaaga aaatcaaaac agtcatggtt tgcttaatgg tcttgttggc gatgatacgg
    17701 ttacgaaagg ttacctcaga ttgaccggaa agctctgcct taaacaataa aaaggtgatg
    17761 gcagcagttg tgattttgat tcctccggca gtaccacctg gagctccacc gataaccatc
    17821 tgaatcatat aaagaatatt ggtaggagcc aaggtatcat tataagaaat agtcgcaaag
    17881 cctgcagttc tcatggttac cgtttggaaa aaggacacca tcagctgctg cggtagattg
    17941 tatctggcaa tagtattgag attgtccttt tccaaaaacc atgataaaaa ggtacctaaa
    18001 acaaggataa ctagggttgt ttgcagcact aagcgtgact gattagaaaa ctttttaaag
    18061 gtgatgccat agcagtgagg cctttcaaag aagtattttt taaaggcagt gcctaaatca
    18121 acccaaacag caaagccaag tccgccagaa ataattaaga aggtgataat agcattgatg
    18181 gtagggttta acacaaagtc ctttaagcta gatgatccta gattatcaaa gcctgcatta
    18241 caaaaggcag agacagccag aaagatactg ttaaagatac catttttcca gccgaaacga
    18301 gggataaagt cagtcatgat aaccaaggca gcaaaggcct ccagtgagaa ggtgacctta
    18361 taggcaaaaa agaggtattt ttttaagtcc ttactgtcac cacgattgag ggcggattgg
    18421 agcaaggttt gatcacttaa acgcattttg cgcttgagtg caaaggtgct gaccgcaatc
    18481 agagtgacca atccaagtcc gccaatttgc atgagcatca tggcaattgt ctgaccaatg
    18541 ccattgtaga catctgcaac aggaacgaca gaaagtccag ttacacagac cattgacacc
    18601 acgttgaaaa aatgatcgag gtaaaccgta ttaggaccat tgctgtagtg ggtaaaaggc
    18661 atggataaca agagactacc tatcaaaatg acaatcgcaa agctaaaggt tagccgctgg
    18721 gtcaccgata aggacttgaa aaatgagcgt ttcatgattc ctcctaataa tatctcatac
    18781 tatcatatca aaaatacatt aaaaaagcta agcagtaacc tagccttaga ctgaagcagc
    18841 cctgtttaca ataggccctt cctaacatgc tccaaaagac aatagctttt tttgacatgt
    18901 caggcttaag cttttagctc agagcttaaa agtgctgagt aagattttat aaagtcttaa
    18961 gggctttagt cattgttgcc acagtagaaa acagaatggc gagctcactg cctagcctat
    19021 gttttttctt gctaggcttc aaagaggctt gatgttttga agcgtcaaaa gtaatcttga
    19081 cagggttcta tatggctaat cgatatcact caaggctagc acttagcttt tgtggtttga
    19141 tcacatgatc attggctgtg gtcatagcgt cagctccctc ctactagcct ctaatggcta
    19201 ataggaggat caagggcaac aaaaaatgtt cagacagcct ttaatcaagg ctgcctgaag
    19261 cagcattcta tagcctctta caatggtttt ttattaggaa taccggcttt tcgagggtac
    19321 ttgtttggcg tttccttttt cttttcgaca agagtgatat agcggccatc tccattagga
    19381 agttggtagg gctggtgatc aagcacctta gcaaaaagta gctgaagtgc ctttttagct
    19441 tcttctaatt cttggtccgc tgcttgtgcc tttaaagcaa tcagttttcc cttgattttt
    19501 aaaaaaggaa tggtcaactc agacagaatc tgcatgcggg caacagctct agcagttacc
    19561 aaatcaaatt ggccacgaaa ttgcttgtct tgtccaaaat cctctgccct accatgatag
    19621 aaatgtactc cctctaatcc tagctcttta gcaaggagct gaagaaaatg tatgcgctta
    19681 ttgagagaat caataatggt aacatcaagc tttggaaaca taattttcat aggaatgctt
    19741 gggaagcctg ctccagcccc aatatctaac agcctgagag gctcatttgg aatatatccc
    19801 tgtaaaagcg gagcaacaga gtcataaaag tgcttgagat agacttcatt ttcttcagtg
    19861 atggctgtta agttgatctt acggttccaa tcaaccaaaa gcttaaaata agtgtcgaat
    19921 tgttcttttt gatgatttgt cagagcaaat cctgcttgct ccaggacaag gtaaaaggct
    19981 tggggtgtca tatatatcct ctgtttttaa ttaattgcta ctattttagc ataaaatagc
    20041 agaaaactgc tgaaaagtcc cttcaatact tgctattaaa ctgaaaattg ctataattga
    20101 gacacaaaga ttaaaggaga attacaatgc caatgttttt agtaatagta gcccttatcg
    20161 gtgtgctggt tgtttggctg atggttagct ataatggcct ggttaaagct cgtatgcata
    20221 caaaagaagc ttggagtcag attgacgtgc agctaaagcg tcgcaatgac ttgattccaa
    20281 accttgttga gacggtcaaa ggctatgcta atcatgaaga gaaaacctta gaaaagatta
    20341 ctagtcttag atcacgtgtg gctgatgcta ctacaccgca ggccacaatg gcagcctcca
    20401 atgaattgag caagcaggtc actagcctct ttgcagttgc agagagctat ccagacttaa
    20461 aggccaatag taatttccta aaattgcaag aggaattaac caatacagaa aataaaattt
    20521 cttattcgcg tcaattattt aatacaacaa catcgcatta taaccttaag ctagaaagct
    20581 ttccgagcaa tcttgtggct aaattgtttg gcttcaagcc aagtgagttt ttacaggttc
    20641 ctgaagctga aaaagaggtt ccaaaggtag actttaccgt ctagtctaat gcggctaatc
    20701 aaggtcagaa gaggacatca atgctttatc aacaaatttc acaaaataaa cgacgaactg
    20761 ttatcctgct ttttgccttt tttgtcttac tggtagtgat tggcgctgct gctgggtatt
    20821 tactggctga cagctaccag ctgggggctg cttttgctct gattattggt gctatttatg
    20881 cctttagcat gatttttcag tcaaccagcc tcgttatggg aatgaataag gctaaggaaa
    20941 tcacagtaaa cgatgctcct gatttctttc atattgttga ggatatggct ctggttgctc
    21001 agattccaat gccaagagta tttatcattg atgatccctc actaaacgcc tttgccacag
    21061 gctccagccc tcaaaatgca gctgttgcgg caaccactgg tctactaaag gtgatgaatc
    21121 gtgaggagtt agaagcagtg attgggcatg aagtcagcca tattcgtaat tatgatattc
    21181 ggatatccac tattgcagtt gctttagcta gtgctgtcac actgatttcc agcattgggg
    21241 ggcgtatgat gtggtatagc ggtggcagga gacgtgataa cgatcgcaac gataatggct
    21301 ttggcgctat tatgctgatt ttctcaatct tgtcactgat cttggctcct cttgcggcct
    21361 ctctggttca attagccatt tctcgtcaaa gagagtatct ggcagatgcc agctctgtcg
    21421 cgttaaccag aaatccagag ggcatgatta gggctctaca aaagctaagc aattcacagc
    21481 ctatgactca tccagtagat gatgctagcg cagccttata catcaatgag cctagaaaaa
    21541 aagaaaagct tagcgcttta tttagtaccc atccgccgat tgaagataga attgaacgct
    21601 tgaagcatat gtgagagctt gagactagct cagctctcat ttttactagc cataatgttc
    21661 agaaaacatc attaattaat tgttttgacc cggacatttt ttaagacttt tatggaaatt
    21721 tgggctattt tcataggggt tttatggtta aacatttgat tgttggcttg tcaatactta
    21781 tttgtatcca gacttaatgt taaaaaaagt tatgaatttg tcataaagct attgacaaat
    21841 tcttgatatc atagtaaaaa tagattagag ttttattagg aagtgtttta taggagaaag
    21901 catgttatct gtttcagata ttagaaagcg accggaaggc attcgctttg agagagagta
    21961 cgatgttaag gaagcgctgc ttatacgtga tccgcaggtt atagatatta ataacgtcag
    22021 agcttcgggg agagctcagt ttgatgacgg cttgtatcta ttagagtatc agctgggcta
    22081 tcagattacc ctgccctcga gccgttccat ggcgcctgtt gtcttagatg agatgcagac
    22141 ggttcaggag ctgtttatcg aggaagcaga tgtggcaagt aagcaggaaa tggttgatga
    22201 aaaccttgtc ttagtcttat cagaggatca gcttgacctt gaagagagta ttattgacaa
    22261 tattttgttg gcgattccct tgcaggtatt gacagaggct gaaaaggagt cacaaatctt
    22321 gccgacaggg gaggattggg cagtcttaac tgaggagcaa taccaggccc agcagaagga
    22381 aaaagcaaaa gacaacagtc cttttgcggg cttacagggt ctttttgatg agtaaaaata
    22441 aaaattaaag atgtctgtat tttttatttg aaaaaagaac agttgtctgg tatactttat
    22501 aaatatacgg catattagtc attttgatga ctaaatagca atacttgatt aatacaaaat
    22561 ggatgaatct tgtacatagc tgataagggg ctgtgataca ggaagtaagg attggtgtaa
    22621 tgacaaagaa aattttaatt atcgaagatg aaaagaatct tgcaagattt gtttcgcttg
    22681 agctacagca tgagggttac gaggtgaccg tcgaggttaa tggtcgtgag ggcttggaga
    22741 cagccctaga gaaggacttt gacttaatcc ttcttgattt gatgcttcct gagatggacg
    22801 gatttgaagt gacacgtcga ttgcaaacag aaaaaacgac ttacatcatg atgatgactg
    22861 cgcgtgactc tattatggac gttgtagctg gcttggatcg tggtgctgac gattacatcg
    22921 tgaagccatt tgccattgag gaattgctgg cgcgtattcg tgctatcttc cgtcgtcagg
    22981 acattgagtc agagaaaaag actcctagtc aaggcgttta ccgcgactta gtcttaaacc
    23041 ctcaaaaccg ctctgtcaat cgcggtgatg acgagatttc actgactaag cgtgaatatg
    23101 acctgcttaa tattttgatg acaaacatga atcgtgtcat gactcgtgag gagctcttgt
    23161 ctaacgtttg gaaatatgac gaggctgttg aaactaacgt tgttgatgtt tatattcgtt
    23221 accttcgtgg gaagatcgat atccctggga aagagtctta cattcaaact gttcgtggaa
    23281 tgggttatgt gattcgcgag aaataattga tggcaaagca gaaaaaatat aagaaaacgt
    23341 taccaaaacg tttatcgaat cttttgttcg ttctcttctt ttgcattttc tctgccttta
    23401 ccctactcgc ttatatttca acaaactact ttttgttgaa acgagaaaag caaactattt
    23461 ttcaggctgt taacattgtt agagttcgtc tctctgaggt ggactctaat tttacgttag
    23521 agaatttagc agaggttctc tataaaaatg acagaacgca tttaaagatt gatgacgcaa
    23581 atggtagtcg tattatcaga agtgaacgaa atatcaccaa cacgctcaat gccaatgagg
    23641 atatctatgt ctacaatgtt gataagcaaa tgatcttcac aacagatgac gaagaggcct
    23701 cgccaggctt aaatggaact attggtaagg taaccaagga ccacattgag gagcaataca
    23761 agggcttttc aatgactcag aaggtctact ctaataagac agggaagttt gtaggctatg
    23821 ttcaggtttt ccatgacttg gaaaactact acatgatcag agcacgcctc ttcttttggc
    23881 ttttggtggt tgagctcttt ggggttggtc tggcgtattt cattatctta attgtcacac
    23941 gcaacttctt gaagcctctg aacaatcttc atgatgtgat gcggacaatt tccaaaaatc
    24001 cagataatct gatgctgcgc tcgggtattt cctcgggtga tgaaattgag gaattgtccg
    24061 ttatttttga taaaatgctt gataagattg agacgcatac acgattgcaa tcaagattta
    24121 ttagtgacgt cagtcatgag ctgcgcacgc cagttgccat tatcaagggg catattggat
    24181 tattgcagcg ctggggcaag gacgatagtg ctattttaga tgaaagcctc actgcagctg
    24241 cgcaagaggt tgaccgaatg gctattatga tcaatgacat gcttgatatg atccgagtac
    24301 aggggtcctt tgaagggcat caaaatgata caactgtttt agagagctct attgagaccg
    24361 ttgttggtaa ttttagggtc ctgcgtgagg attttgattt tacctggtac tctgaaaatc
    24421 aaagaaccct agccaagatt tataaaaatc attttgagca ggctctgatg attttgatag
    24481 ataatgcggt caagtattct aggaaggaaa agaaaatcgt catagaatta gcggttaatg
    24541 ctagcaatga agctgtggtt aaggtcaaag acagaggtga ggggatctca gaagaggata
    24601 ttaagcatat ttttgagcgc ttctaccgca ccgataggtc cagaaatcga accagcaccc
    24661 aagcaggtct tgggattggc ttatccattt taaagcaaat tgttgatggc tatcatttac
    24721 atatggaggt tgagagtgag ctaaataaag ggtcggtctt tattttgcgg attcccttag
    24781 ctgatcatca aggctcatag ctgtatacct gcctgagtat ctagtagatg ctcaggcttt
    24841 tgactgttct aatgtgtggt gtgatgatga ggtgtttatc agggaaggag ggctcttgga
    24901 ggtaaacctg agtgcttgtc tattcttttg ttatccctaa aattatggta aaatagggta
    24961 ttagattaac gatagaattg gggtgtttgc gtgcgttgtc cgaaatgtaa ctataataag
    25021 tcaagtgttg ttgatagtag acaggcagaa gatggcaata cgattcgtcg ccgcagagaa
    25081 tgcgaaagct gtcacacgcg ctttacaacc tttgagcgct tagaagagct tccattacta
    25141 gtgatcaaaa aggacgggac tagggagcag ttttcaagag ataaaatctt aaatggtgtt
    25201 gttcaaagtg cccaaaagcg tccggtgtca agtactgaca ttgaaaatct catttctcgc
    25261 attgagcaga aggttcgtac agcctatgaa aatgaggtgt caagtactgt tattggcaat
    25321 ctggtgatgg aggaattagc agagcttgat gagattacct atgttcgttt tgctagtgtc
    25381 tataaaagct ttaaggattt agacgaaatc gaagagctct tacagcagat tactaatcgc
    25441 gttagaggaa aaaagaagag cagtgtagat gatgaagcct attgatacct tttcttatat
    25501 taagcataat caggttcaat acgattcaag cagcctgatt cagttgtatt ttcctattat
    25561 tggaaatgac gcagtggcag tttatcagta tttggttcac ttttttgatg atggctcagg
    25621 agcccacaaa tttagtgata ttttaaacca tctgcagttt ggaatgaagc gcctagagga
    25681 agccttggtg atgctgacag ctattgattt gctggtctta tatcagctgc cagatgctta
    25741 tttgataaaa ctacatcagc ccttgggcag ggaagccttt ttaaataacc caatttatcg
    25801 taggctttta gagcaaaaga ttggagatgt agcggttttg gagttgcaaa tggtgattcc
    25861 gaaccaggct agaaacatct caaagacctt ttcagatgtt tttggaatag actctcagga
    25921 gcttaagcag cctcagccat caaagataaa ttttgattta gatagctttc agcagctaat
    25981 gcggcgtgac ggtcttaggt ttgaggatca tcaaaaggac gttatcagtc tttacagtat
    26041 ttctgagcaa taccacctaa cctggtttga cacctatcag ctggctaagg caacagcagt
    26101 cggcggcagc attcgcccag agcgcatgct agtcaagaag cagcaagagg gcgctcaaaa
    26161 aacaagtgaa tcgttctcac cagctgagca ggttgttctt agagagtcta agcaggacac
    26221 gcctcttgtc tttttagaga agatcaaaaa agctaggcga gctagagtca caaaggacga
    26281 aaaggaattg ttgctgactc tagcccgcat gaatttcttg gacgaggtca tcaatattat
    26341 ggtattatat accttcaata agaccaagtc agctaatctt cacaagactt atctgatgaa
    26401 aatggcaaat gattttgctt accagcgggt tttaacagcg gaaactgcta ttatcaagac
    26461 acgcgccttt ggtgagcgta agcagcaggc aaagtcacag cagtccaatg tgcctaagtg
    26521 gagcaatccg gattatcaag aaaaaacaag tcaggaagaa caggcaaagc tagagcagtt
    26581 taagcaggct gccttaaaaa ggctggagaa cctaggaaag agtggtgact agatggaaaa
    26641 gatcgggaaa atggtagagc atttgggaca ggctagtcgt gtagctagtg ctgagctgat
    26701 tgaggctata cttgctgatc aggaggtggc tgagtttatc aaggctcacc agctatctca
    26761 ggcagaaata aagctgagtt tatcaaagtt caaccagttt ttagttgagc gccggaaata
    26821 ccagacaggt gatgagacct atattgctaa gggctatcag cccattttgg tcatgaacga
    26881 gggctatgca gatgtgtctt acctagagac aagagagctt gttgaagccc aaaggcaggc
    26941 agctattgca gatcggattc atttggttag tctgccaaga tcttatcgta gggtttcttt
    27001 gtcagctgtt gatgttaaca atgccagtcg tatgcaggtg ttttcagagc ttttggattt
    27061 tgttgagcag tatccagcgg cagagcaaaa gggtctctac ctttatggcg atatgggggt
    27121 cgggaaatcc tatctgatgg ctgctatggc acatgaattg tctgaaaaaa agggtgtatc
    27181 aacaactctt cttcattttc ctagctttac gattgatgtt aaaaatgcca tttcaaatgg
    27241 ctctgtcaaa gaagagattg atgccatcaa gcatgtccct gttttaattt tagatgatat
    27301 tggtgcagag caggcgacct catgggtgcg tgatgaggtg ctacaggtta ttttgcagca
    27361 tcgtatgcta gaggatttgc caaccttttt cacctctaat tacagctttg cagatttgga
    27421 gagaaaatgg gcaaagatca aaggaaatga tgagacctgg caggccaagc gtgttatgga
    27481 gcgtgtgcgt tatttagcac gtgaatgcca tttagaaggg gttaatcgcc gccagggcta
    27541 gctaaacgct agctcaagcg atggataatg agataaagaa aaggagaatc atggttttac
    27601 ctacagttgc cattgttgga cgtcctaatg ttggaaagtc cacgttattt aaccgaattg
    27661 caggagagcg tatttctata gttgaagacg tcgaaggggt tactcgcgac cgcatttaca
    27721 cgactggtga gtggcttaac cgccaatttt cattgattga cacaggtggt attgatgacg
    27781 ttgatgctcc ctttatggag caaatcaagc atcaggctca tattgcgatg gacgaggcag
    27841 atgttattgt ctttgtggtt tctggtaaag agggcgttac tgatgcagac gaatatgtct
    27901 ctaagctctt gtatcgtacc aacaagccag tgattttggt tgtcaacaag gtggacaatc
    27961 cagagatgcg aaacgatatt tatgattttt attctcttgg cttaggagat tccttcccgg
    28021 tatcatcagt tcatggtatt ggtacgggtg atgttttaga tgctatcatt gataacctgc
    28081 cgatagaaga gccagtagaa aacgacgatg tgattcgctt tagcctaatt ggacgtccaa
    28141 atgttggaaa atcaagcctc attaatgcga tcctaggaga agagcgtgtc attgccagtc
    28201 ctgttgctgg tacgactcgt gatgcgattg atacaagctt taccgatgaa tccggtcaag
    28261 cctataccat gattgatacc gcaggaatgc gtaagtccgg caaggtctat gaaaatactg
    28321 aaaaatactc agtgatgcgt gccatgcgtg ccattgaccg atcagatatt gtgttaatgg
    28381 ttattaatgc cgaggagggc attcgtgact atgataagcg gattgcaggc tttgcgcatg
    28441 aggcaggtaa gggcatgatt atcgttgtta ataagtggga caccatcgaa aaggataatc
    28501 atacagtagc taggtgggag gctgatattc gtgatcaatt tcaatttttg acctacgccc
    28561 ctattatctt tgtttctgcc gttacaaagc agcgcttaaa caggcttcct gagttgatta
    28621 agcgtatcag tgatagtcaa agccagcgga tctcgtcagc tattttaaac gatgtgatta
    28681 tggatgctat tgcgatcaac ccaaccccaa cggataaggg acggcgtcta aagattttct
    28741 atgctacaca ggtttctgtg aagccgccaa cctttgttgt ttttgtgaat gaagaagagc
    28801 tgatgcactt ctcttatctg cgctttctag aaaaccagat tcgtgctgct ttcacctttg
    28861 aagggacacc aatcaagctg attgcgcgca atcgcaaata agccctttta ttactcttgt
    28921 tagtattgga agcagcgagt gctgttgatg tgcggtgtct agaccttgtg tgtcaggact
    28981 tttgaccgac caataagcct taccagaaat gagaggctgc tatccaaata gagcttacca
    29041 gcaagcaagg cgtgccaagc attgatgtca catgataatc attagcccta ggctagtgat
    29101 tttttagtgc tttaaagcct atcagaacag ctatatacag ctactcaaat atgttttaat
    29161 agcctttaag agagattttt gcaggaaatc taagctgaag tttgttataa tcaaaggata
    29221 agcaaaaagg tgggagcaga tatggctaga ttaattccgg ggcggattcg caatcaaggc
    29281 atcgagcttt atgagcaagg cttggtgaaa atcatagatg acaggactga ccttcttcga
    29341 gcagaggtgg atacttatca ggttcaatat ggtatcaatg atgaggatat taggtgtcag
    29401 tgtgattatt ttgagcgaaa gcagtattgc cagcacattg cggctctaga atattttctg
    29461 aaaaataatc agaagggcaa gtcgctctca gagcagctta acaaccagct ggaaagtaag
    29521 gaggaaacta aaaagctgac ctcctttggt agtctttttt tggacagttt gcacatgaac
    29581 gaggacgaca cgaccaaata taggctttta gcttctggtg ctaaaagtcc tttctcatct
    29641 gattactggt ggagccttaa gataaatcgc ttgcccggag agaaggctta tgttatccgc
    29701 gatatcaagg cctttattca tttggtcaaa gttgagggct tttaccagat tggaaagaat
    29761 tactttgagt ctctttccat attgcagttt gatcaggcta gtcaggagct gattcgtttt
    29821 ctttggcgtt tatcaacgca ttcagataag ttagattacg aatggctatt tcctaaccac
    29881 gctcgtcatc ttcggttacc ggcaggcttt tttgaggagg gcattgacct gctgacgggg
    29941 ctttacgagt tttcatttga gacctcctct caaacctatt ctcatcttta tgttcgacct
    30001 ctggaggcag aggctggtct ctttcagttt acagttgatg ttcatcgcag ctctattgag
    30061 ctttacatta aggaaaaaaa tatagagtat tttttcaata atgaatacct gctatacatg
    30121 aacacctttt accacctgag cctgaagcag caaaaaatgg ttcaagctat tcgcagcctg
    30181 cctattgagg ccgatttggc caagcacatt cattttgatc ttgatgatca ggctaagctg
    30241 gcagctagct tgctggaatt tcgagagctt ggtcaggtga aggctcctaa aagctttgat
    30301 attagagatt tccaagtgac ttttgtcttt gatattactg aaaaaggtga gttgacctct
    30361 cagctgattt ttgactatgg gagcattcag atcagtgata aggcaagctt agaccagctc
    30421 ccctttgcta gccattataa aaaagaaagc agtatttatc gtgccttgaa gcgctttggg
    30481 ctttctccgc agttttttgc taagaaagcc ttgactgacc ccaaggactg gtatcgcttt
    30541 tttacagaag ctgttcctta ttttgaaagt ctaggtaggg ttcagctttc ctctaagctc
    30601 caagatcagc gcttaatgga aagccctcag cttacagtca aacgtgaggg aggtctttta
    30661 gatatttcct ttgatttttc aacggtttgt cagactgata ttgaaaaggc tttggccact
    30721 ttgtttagtg atcgctctta ttttgtcaat cagtcaggca agctggtcgt ttttgatgaa
    30781 gagacacaaa aaatcagccg tagcttacag gaactaagag ctaagcagct ggcaaatggt
    30841 cacctccagc tagaaggaat agctgccacc cagctgtctc atctattttc ggatctgtct
    30901 tctgttcatt tttctgagga gctagagacc ctaatcaagg acctgcagca cccggatcgc
    30961 tttgagctgg gagagctggc cgttaaggcc aaggtgagag attatcagct gcagggcatc
    31021 aaatggctct ctgtgcttga taagtatggc tttggtggta tcttggcaga tgatatgggc
    31081 ttgggcaaga cactgcaaat cattgccttt ttatcaagca ggctaaccga gacctccaag
    31141 gtgcttatct tggcaccctc tagcttgatt tacaattggt tagatgagtt tagtaaattt
    31201 gcccctcaga tagatgctgc tgtatcctac gggctaaagc cggcacgaga tgctcttatt
    31261 caagaaggac atcaggtgac gattaccagc tattcttcct ttaggcaaga tttagaaacc
    31321 tatcaggcaa atgattatga ttatttaatc ttagatgagg cgcagatgat taaaaatgcc
    31381 cagaccaaga ttgctcagag cctgcgtgcc tttgacgtga agaattgctt tgctttatct
    31441 ggtacgccga ttgaaaataa gctgcttgaa atctggtcca tttttcaaat tgttctgcca
    31501 ggcctgctgc catctaaaaa agcctttttg aaaatggagg ccagagacgt ttctcgctat
    31561 attaagccct ttgtcatgcg acgcaaaaaa gaggaggtct tgccagagct accagaatta
    31621 atcgagatga attattacaa tgagatgtcc gatggtcaaa aagcgattta tctggcacag
    31681 ctaaggcaga tgcaggagcg gctgtctgct gcaactgatg atgatattaa tcgcagtaag
    31741 ctggaaatcc tgtctggtat cacacgtcta aggcaaatct gtgatactcc tagcctgttt
    31801 atggattatc aaggaggaag cggtaagcta gacaatctaa gaaccttgct gctgcaaatt
    31861 aaagaaaacg gtcatagggc tttgctgttt tcacaattta agggcatgct ggctcttgtc
    31921 aagcaggaaa tggatcagct tggcttatca tcttatacca taacaggctc aacaccggcc
    31981 aatgaccgtc aagaaatgac acgtgccttc aataatggct caaaggacgc ctttttgatt
    32041 tccttaaagg ccggtggtgt tggactcaat ttaacaggtg ctgatactgt tattttgatt
    32101 gatctatggt ggaacccagc tgtagaaatg caggccatta gtcgtgctca tcgtattggt
    32161 caggaggaca atgtagaggt ttaccggttg attacccgcg gaacaattga ggaaaaaata
    32221 ctggagcttc aggaaaataa gcgtcatctg attaccactg ttttagatgg caaacaaggc
    32281 ctagcaagca tgtctgtcga ggagatcaaa gaaatccttg gtcttcagcc ctagcatgta
    32341 tggcttttag cacacgctct taagcctatc agctaaaggc tagtgtctgt tctctataac
    32401 aaataaggca agagaataga ggtgatgagc tagtcacatc atttttgctt tgctgccttt
    32461 ctttttagga attactttga aaaataggat tatttagttt ataataggga atgctatagg
    32521 aaggagagtg agatagaatg acaaagcatg cgtttcctct ggttgcagat ggtgagccta
    32581 ttattgagtc agctaggcag atggctttat atgaaaacga agatttgatc acaaatattg
    32641 ctggcagcta tcaagataaa cattacgacg acatcataag agaccatcaa tttgctgaga
    32701 agactcctgt cgtctctaaa ggatcccttc atcattctcc agttgtcgat gaagatcata
    32761 gctacgctca aaaggccaga aggcaagcaa agcaggatgt caaagaaaaa agacaggctt
    32821 atattgctaa aaatatggct tatagcccaa agcaggcaag caagaaaggt caaagtgggg
    32881 ccttctcttc taaaaaacca gcgacagaat tgagccgttt tacagagaaa ttaaaccaag
    32941 agtcttatat tttagctgag cttcctcgtc aatataagga gccgcaaaat accagccaag
    33001 cagctgtcaa aaaaaataat tatgactttt tgaagcgcag ccaaatctac aatcatcaag
    33061 aagacagaga tcatcgtgaa aagaccattg ctcaagagct aaacctgagt cgctttgaag
    33121 atattaagta agctttatac agccttatgt ctgtcaacat taaaaggagt taacatgtca
    33181 aaaacctatc attttatcgg aattaaagga tctggaatga gtgccttagc cctgctgctc
    33241 catcaaatgg ggcataaggt tcaaggcagt gatgtggaga agtattattt cacacaaaga
    33301 ggcctagagc aagcaggcat taccattttg ccctttagcg aagataatat ttctccggat
    33361 atggagctga tagcaggtaa tgcttttcgt gaggacaaca atagcgaggt tgcttatgcg
    33421 atgcgtcatc agctgccctt taaacgctac catgagtttt taggtgagtt tatgaagcag
    33481 tttactagtc ttggtgtagc cggtgctcat gggaaaacct ctaccacagg cttgttgtca
    33541 catgtgctca agcacatgac ggctacttct tatttgattg gtgatggtac tgggcatggg
    33601 gctgccgatg ctcgttattt tgtgtttgaa tcagatgagt acgagcgtca ctttatgcct
    33661 tatcacccgg aatattctat tatcactaat attgattttg atcaccctga ttattttaca
    33721 ggccttgatg atgtgttcaa tgcctttaat gactatgcta agcaggtgaa aaaggctctt
    33781 tttgtttacg gtgaagatga ggaattaaga aagattagct ctcctgcacc gatttactat
    33841 tatggctttg aggacactga tgatttcgta gcctttgata tcacacgcac gacaaatggc
    33901 tcagacttta aggtaaagca caagggtcat gctattggtc agtttcatgt tccagcctat
    33961 gggcgtcaca atattttaaa tgctactgcg gtgattgcta atttatttat tgcaggcttt
    34021 gatatgaagc ttgttgcaga gcatctgaag agcttttcag gggtgaagcg tcgttttact
    34081 gaaaaggtga tcaatgacac tattattatt gatgactttg ctcatcaccc aacagaaatc
    34141 attgcaacgc ttgatgctgc taggcaaaaa taccctaata aggaaatcat cgctattttt
    34201 cagccacaca cctttacaag gaccattgct ttgctagatg actttgccca tgccctaaat
    34261 gaggctgaca gtgtttatct agcgcctatc tacggctcag cgcgtgaggt tgataagggt
    34321 gatgtcaagg tggaggatct agcggctagg gttgagcgcc cagccaaggt catctcagtt
    34381 gacaatgtat caccgctgct ggatcatgat aatgcagtct atgtttttat gggagcaggt
    34441 gatattcagt tgtatgaacg ctcgtttgaa gagctgctgg ctaacttaac taaaaataat
    34501 caatgattaa gcgacctgcc ttaggcaggt tttctcgtcg taaaggagga cctatgctaa
    34561 ttagacatgt gaatcagact gactgggaga ttattgctga tatcgaacag gccaattttt
    34621 ctccccaaga ggctgtagca gccaatgtga taaaagagcg tgcagagctt atttcggata
    34681 cctttcttgt ggctgttatc gccaatcagt ttgtcggcta tatcgaagga cctgtcattg
    34741 ctgagccaag gcttgaggat cacctatttc atggtgtgac caagaatcca gcaagaggtg
    34801 gctatatagc cattaccagt ctttctgttg ctcctggata ccaaaagcag gggattggca
    34861 cagctctctt agctgcaatg aaggatttag cagttgcaca ggatcggctg ggtatcatac
    34921 ttacctgtca tgactatttg attccttact atgagatgaa tggttttcaa gatcaaggcc
    34981 tgtcagcttc aaagcatggt ggctctgttt ggtatcaaat gctatggcag ccataggaag
    35041 gctattaaag cttagcatgt attaagaatt agtaacaaaa gggggatttt attgcattta
    35101 tagtgcaatt aggatataat ggcggttgat taagtttagg aggaatggct ttgactgatt
    35161 ttaaagatga tgagcaaaga cgtcagcagc aaaaaagctt caaagaaaag attctagccg
    35221 aattagaaaa agcaaatcag attagaaaag aaaaagaaga agagcttttt aaaaaggatc
    35281 tagaggttca agaggctgct agaagaacag ctcagcttta tgcagaatat aaaagacaag
    35341 aagcactaag caataacccc aaacaagcgt ctgatatagc agctgcgtcg caagagacga
    35401 cctcaacggc ttcaacagcc cacacctctg cgattaagct agaagagaca gcagtagcta
    35461 ctggggatca agcattgtcg ccaccagagg agcctgcatt gagtgaaagc ctgcttaagg
    35521 aagaggcaag tgtcgaaggt cagactaaga agggtggtcc agtgagaaga aaaacaagta
    35581 agcgccagca gacagatcga atggccaaaa aaatttcgac agtactgata tcgtcgattg
    35641 tcgctattat tgtggtgatt ggcctcgcag ggacagccta tgtgtatagt gcccttaacc
    35701 ctgttgacaa aaatagcgat gactttgttc aggttgaaat cccagccggc tcaggcaata
    35761 agcttattgg gcagatcctt gaaaaagagg ggctgatcaa aaatagtacc gtctttagct
    35821 tttacactaa gtttaaaaat ttcactaatt ttcaaagtgg ctactacaac ctacaaaaga
    35881 gcatgagcct agaagacatt gcccaggcct tacaagaggg tggcacagca gagcctacaa
    35941 agccagtact aggaaaaatt ttaattccag agggctatac cattaagcaa attgctaagg
    36001 ccatagaaac taatagtagg gcaaagaatc gtagcaaggc taaaacacca tttcactcaa
    36061 aggatttctt gaatttggtg acaagtgatg cctttattca agagatggct aaaaaatatc
    36121 cgaaattgct aggagatctt ccaagcaagg aagtagctac ttatcagcta gaaggctacc
    36181 ttttccctgc gacctataat tattataagg aaacaacact aaaagacctt gcagaggaaa
    36241 tgattgcagc ggcaaatgca aacctagcgc cttattatga ggcgattgca gctagtggca
    36301 agacagttaa tgaggtgctg actttggcct ccttagttga aaaggaaggc tctactgatg
    36361 acgatcggcg tcaaattgcc agcgtatttt acaatcgctt aaataatggc atggccttac
    36421 agtctaacat tgctatattg tatgcaatgg gtaaattggg agaaaagaca accttagcag
    36481 aggacgctgc tattgacaca accattaatt ctccttataa tgtttatatc aatactggct
    36541 taatgcctgg tccagttgat agtccagggc ttgcagctat tgaggcgact atcaatccag
    36601 cggcaacaga ttacgtttat tttgtagccg atgtgcgtac tggtgaggtt tattatgcaa
    36661 aaacatttga agagcactct gcaaatgttg aaaaatatgt taacagtcaa attcagtaag
    36721 gacaaacatg gtgctttagc atcatgtttg tgtttctgat tcgtcaaaag aaaaaggaaa
    36781 agagaaagat aatggcagaa aagacttatc caatgacagc agcagaaaaa gaacagcttg
    36841 aaaaggaatt agaagagcta aaattagttc gtcgtccaga ggttgttgag cgcataaaaa
    36901 tcgctcgttc gtatggagac ctttctgaaa actctgaata cgatgctgct aaagatgagc
    36961 aggcttttgt tgagggacaa atctcaacct tggagacaaa gattcgctat gctgagatta
    37021 ttgatagcga tgctgttgcc aaggacgagg tggcgattgg taagacagtt gttgtccagg
    37081 aggttggcac acaaacaaca gacacttatc atattgtcgg tgcggcagga gcagatattt
    37141 tttctggaaa gatttcaaac gagagtccaa ttgcacaggc cttgattggt aagaaaacag
    37201 gagataaggt taagattgag tctccagcag ctacctatga ggttactatc atcagcgttg
    37261 acaaaacaca ataagactta tctgactatc agtgcagtgt cctgatagtc tttttagtgg
    37321 cttgcttttt aatatcagtt gttgtggtct attaaaaaga gctgcacttt agaaagtttt
    37381 aactaagata ctttatgacc tagtctcata cattaaaaaa gcgaacaggt ctaattttcg
    37441 gaatccctga aaattagacc tgttcgtttg ttttatcttg agtcagactt ttgtcacaga
    37501 ctcttttagc tatcttagcg acgctttttt tgtttaccgg cgtttcggtt taacttagtc
    37561 ctcttgcttg tgctaagggc ttgcttttca gctgtaacgt ccttgcgtgg ctggtgagat
    37621 ttataggcct taggagggtt ctttgcgaac tcctctgcaa tttgcttgcg gagccttggt
    37681 tttaaaaggt aggttgtgat caattgctga atgatactaa agaaaccacc aactagccaa
    37741 tacaagccta atccggcagg caggtaaaac gacatgacaa tcatcataat tggcatggtg
    37801 tacagcatgg ctttcatttg ttcacgttgc tcctcaggga ctgccatcat tgacagccag
    37861 gattgaacga agtataaagc cgcaattaca gctgtaagca agacgctgcg atgccccagg
    37921 tcaatgccca taaaggtact tgttgagact cccttggtaa attggaccgc aacatacatg
    37981 gcagaaaaga aaggcatttg aatcagcagt ggcaaacagc ctataccgcc tagcgggttg
    38041 actccatttt cacgctgggc cgccattaat tctgtttggg ctgccatttt ttcttcagtg
    38101 cttgtagcgt ttttgatgcg ttgattaatt ggctcaaaaa aaggctttag gtaggccatt
    38161 ttttctgatt ggtagcttgc cttccatgat tggtagagcc caagtggtag gataatcgtt
    38221 ctaacaataa tagttacaac aatgatggca agaccatagc ctagggcggt gctgttagca
    38281 aagtaatcaa tgagaaagga aacgggcttt ccaaggtaat cccaaatgat gccctccggg
    38341 tgccccttgg cgtctctgcc gacacaccct gtcaatgtca gtaggaccga taaggcaagt
    38401 cctgagaaaa gtatgcgatt cgttttgagt ttcaatgtgt ttgtccttta atttttaata
    38461 tacctaacca ttttactgtt tttttgagaa attaacaata gttctacagt aggattttta
    38521 attgctgatc ctaaaatcat ggaaatcctc aaagtgagat ggattaacat caacataggt
    38581 cacctttgcc catttagaag gtccttttct gatttcctgg ataaagcgcg tcatctttgc
    38641 agggtcacta gcctgtgcta aaatctcaac agtcccatca ctattgttcc acacgcggcc
    38701 gtaaatatca ccaatttcca aagctagtgc gtaggttgaa tagcgaaagc caacaccctg
    38761 caccctgcct gaaacgatta gtctgacctt tttcataagt cacctctttt ctttttatta
    38821 tagcatagat agcttataaa tactaaaagt tgtcatggag caggcagcca aaggataggc
    38881 aaagactgca agtgggctat ctgctgaggt aaacaatagg tcttagtgca gcaaggctat
    38941 gtttatggtt agctctcctt cttgtcttct aaaaaggaaa gctaatgggc ttacgacacc
    39001 tgataagggg agaaagctcc ttttaggctg atagccttct gatggttttt atgcaaaaga
    39061 gtgaacaatt ttgtgatata ataagaccat gattatcaca tcaaaagcaa accatttgat
    39121 taagcaggct aagaaattac tgcaaaaaaa gcatcgcaag cactcttact tgattgaggg
    39181 ctggcaccta tttgaggagg ctcagagatc tgggcaggaa ttgatacata tttttgttct
    39241 ggaggaaatg gcagagcgct tatcaggctt tgatcaggtt gtcatcgtca gtccagagat
    39301 tctaaaggag ctgacgagct ctcccaatcc acagggcatt attgctgagg ttaagctttg
    39361 tcaacaggcc ttaccgacta gctatgctgg aaaatatttg attttagagg acattcagga
    39421 tccaggcaat ctagggacaa tcattagaac agcggacgca gcaaagtttg atggggtgtt
    39481 tttgtctgag aagtctgcgg atgtctacaa tcaaaaaact ctacgctcca tgcagggcag
    39541 tcattttcac ctgccgattt ggcgaacgga tatttatcag gtcagtcagg tgatgcagca
    39601 gcaaaaaata ccagtgctag caacgacctt gtctcaggat tcgattgatt acaaggacct
    39661 ctcagctagg agcagccttg cccttgtttt aggaaatgaa ggtcagggca ttagtcctga
    39721 gatggcagct ttggctgatc agctgattca tattagcatg cctggacaag ctgaaagctt
    39781 aaatgttgca gttgcagcag gaatcctcat tttcagccta atttaagcta gtatggtata
    39841 ataatgatgt gaggtgatta gtgtatgcat tatacagaag atacagaata catggagcat
    39901 gttggtcatt tgattgctca ccctcgcttt caaaggcttg gagatattgt tcagcatcac
    39961 cattctactc gcttagagca ctctgtcaat gtttcttatt ctagctatag gctggcaaag
    40021 aggcttggct tagacgccaa gagtaccgca cgaggtggct tgctacacga tttcttttat
    40081 tatgattggc gagtaaccaa gtttaacaag ggacacgctt gggtgcaccc tagaattgct
    40141 gttcgaaatg ctaaaaaatt aacagcactc aacaaaaaag aagaggatat tatcctaaag
    40201 catatgtggg gagctactat tgcttttcct cgctataagg aaagctatat tgttaccttt
    40261 gttgataaat attgggcggt caaggaggcc atgacgccgc tgcgtcaaaa atggacgaac
    40321 cgtcgcttcc tgcgtcgaaa gacgcttcaa agtcacaatc attaagtaaa aaaaggagtt
    40381 atgatgaacg ataatgttat ttacacacag tctgacgcag gcttgagcca tttttttgcc
    40441 aaggtctata gcctggttgg tatgggagtt gggctttctg cctttgtttc ttatttgatg
    40501 ctgtttccat ttaggcaaaa tttagtctcg attgttcttg atcatcctat ggtctattat
    40561 ggggcggcta ttgttgagct tgtactggtt tttgttgcta gtggtgctgc acgtcgcaat
    40621 acaccagcag ctttaccctt atttcttgtc tattcagcct taaatggctt taccttgagc
    40681 ttcattattg cagcttatgc gcaaacaacg gtgctacagg cctttatctc atcggcagct
    40741 gttttctttg ctatgtcact gcttggtgtt aaggttaagc gtgatctgtc aggtattcga
    40801 aaggccatgt ttgcagcctt gattgggatt atcgtggcta gtctggtaaa tctctttatc
    40861 ggtagtgacc tgatgagcta tgtgatcagc cttatttcag tgttgatctt ttctggcttg
    40921 attgcttcag acaatcagat gatcaagcag gtctaccaag cctctaacgg tcaggttggt
    40981 gacggctggg ctgtcgctat ggctcttagc ttatacctag actttatcaa cctctttatc
    41041 agtctacttc gtctcttggg aagaaatgac taatagctat tttaagcgca gctgctgatt
    41101 gtcacttaat cgctattacg agaaatcagc gaagctgcag gtgttacctt ttgttagaaa
    41161 agagtggctg ctgctagtaa gaaagtagct gctaggagag cctgatgagc gtgactgtca
    41221 aggaaggcca gttactattg ctaccatcta gggaaggtac caaaaaaagt caagaagcgg
    41281 gcccaagggc tcgtttttgt ttgcttgatt tgtggtaaag tgcttcaaac caagcctata
    41341 tctagtctga tagctcttat cagctgacaa catcatattt acaatgcctg ttggtgtaga
    41401 tttgtaaagc atgctctttt ttggtataat gagaggaaca aaaaatcgag gagaatatct
    41461 atcaatatgt ctacagctat ctggatatta ttaatcattg ttgctcttac agccggtctt
    41521 tttggtggga tttttattgc ccgcaagcaa attgaaaagg aaattggaga gcacccacga
    41581 ttaacgcctg aggccattcg tgaaatgatg agtcaaatgg gtcaaaaacc aagtgaagcg
    41641 aaaattcaac aaacttaccg caacattgtc aagcaatcaa aagccgcaat gactaagggt
    41701 aaaaaatagg ttacggatta gaaatcgtgg tttctaagca atagctaaga gtgaacagtc
    41761 tttgatgtta aaagcttgtt tagagcttgc attgtcagtt agaggtgtca actgttcagg
    41821 ggttaacaat agactcagtt ggctcttacc agctgagttt tttatgcttc aatgaggaaa
    41881 taatcgttat ggacaataga ccaattggtt ttttagattc tggtgtagga ggcttaactg
    41941 ttgttagtga gctgatgcgt cagcttcccc atgaaaaaat catttatatt ggtgattcag
    42001 caagagctcc ttatggtcct agacctgctg aacaaatcag agaatatacc tgggagttgg
    42061 ttcgtttttt attaacgaaa catgtcaaga tgattgtctt tgcttgtaac actgcaacag
    42121 ctgttgcttg ggaggaggtc aaggaggctt tggatattcc tgttttgggc gttatcctgc
    42181 cgggcgctag cgcagctatc aaggctacta gtggaggaaa ggttggtgtt attggcacat
    42241 caatgactat ttcttcaggc atttaccagg aaaagatcca gttgctggct cccactgttc
    42301 aggtaactag cctagcctgt cctagatttg ttcctattgt ggagtccaat gagataagct
    42361 caagtgtggc caagaaaatt gtctatgaaa ccttggctcc cttagttgga aagatagata
    42421 cccttgtttt gggctgcacc cattatcctc ttcttaggac gattatccaa aatgtgctgg
    42481 gaccacaggt taaattgatt gatagtgggg cagagtgtgt gcgtgatatt tctgttcttt
    42541 taaattattt tgagattaat ggcagtcgag atgatgaaca taggcgtcat catttttaca
    42601 ctacagccgg ctcagacagc tttcaagcaa ttgcctcagc ctggctaaat caaacgatag
    42661 atgtggagca tgtgacctta tgagtgataa catttatgaa tacaaggata aagacaattg
    42721 gtttattggc aagatgacag gccataattt aatggctggc tggggggtta accatgagct
    42781 tattgccaaa atagacgata tgttaggtgc gattgctggt gatgtggatt gggaaagtcc
    42841 ggtcggttat gatgtgactg ttattcgtta cgcctcccct tttgccttga ttagctttgt
    42901 tgttggcatg atcaatcaga aagccaatcg agcccttaag gttgttcggc actcaggtgc
    42961 gattttagtg accgaaaacg agcgattgct tgctgtgcat atgccagatg atggcgtccc
    43021 tgtggctgac ttctttggtc aacaggcaga tggctttggg gatacgattt tgattgcgac
    43081 tcgaaatgaa ggcaagacca aggaatttcg ccggcttttt ggtgatatgg gatatcgcgt
    43141 tgaaaatctc aatgattacc cagagcttcc agatgtggca gaaaccgggg tcacctttga
    43201 ggaaaatgcc cgcctaaaag cagaaaccat ttcaaggctt actggaaaga tggttctggc
    43261 agatgattca gggctcaagg tggatatttt aggtggctta cctggggtct ggtcagctcg
    43321 tttttcgggc cctgatgcta ctgatgagac taataatgct aagctattgc atgagctggc
    43381 aatggtattt gatcaaaagg atcgctctgc tcaatttcat acgaccttgg tggttgctgc
    43441 acctggtaaa gacagcttgg ttgtcgaggc tgattggcat ggctatattg caaccaagcc
    43501 aaaaggcgag catggctttg gctatgatcc cttgtttatc gttggggaga ctggacgtca
    43561 tgcagcagag ctagctgctg atgaaaaaaa caagctgtct cataggggac aggcggtcaa
    43621 gaggttaatg gaggtatttc cagcatggca agcaaaacaa tcattgtgat gagcgattcg
    43681 catggcgatc gtgaggttgt ggcagctatt aaaggccgtt accttggaaa ggttgatgcc
    43741 attttccata atggcgattc tgagctagaa agctcagatc ctatttggga ggggattcat
    43801 gttgtggcag gcaactgtga ccatgatagc ggctataagg atagcctagt cacctccttt
    43861 gatggcttga ctattgctca aacacatggg catttgtatc atattaactt tacttgggat
    43921 aggctagatt attttgctca ggagactgga gcggatattt gtttgtatgg gcacttgcac
    43981 agacctgctg cttggcaatt gggcaagact gtctttatca atcctggctc ggtcgctcag
    44041 ccgcgtggtg aggtgaatga aaagctgtac gcgcgtgttg aatggacagc agcttgcatt
    44101 agggtggatt actttacctg tcagcataag tcttacccat cactttctaa ggaatttaaa
    44161 cgatgatagc aaaagaattt gaagcctttt taatcagtca tttggatagc tacctgattc
    44221 cagcagagga gctagccatt tttatcaaca cgcataatgc tgatcatgtc atgctcttat
    44281 tggttagcaa tggtttttca cgagttcctg tcattaccaa ggaaaagcaa tatgtcggaa
    44341 cgatcagcat ttctgatata atgacctatc aagccaaaag gcagctaaca gactgggaga
    44401 tgacgcaaac taatattggc gacatggtca atacaaagat tgagaccatc aatattacct
    44461 ctagcttgac tgaaatcatg cataaattgg ttgattttcc ctttttacca gttgttaatg
    44521 atgacaatcg atttatcggt attattacgc gtaagtccat tttgaaggcg gttaatagcc
    44581 ttttgcatga cttcactgat gaatacacaa tcacaaaaaa atgatagcat ttattgaacc
    44641 ctttctagca agcaaatctc ttgctaataa cagccagcaa tcctatcgct atgatttaag
    44701 gcagttttgc cagcaggtcg gacagcgtat taatcctgaa accctagccc tctatcagca
    44761 aagcttgtct ggccttacgg tagcagctaa aaagcgcaag ctttcaacgg tcaatcagtt
    44821 tttgtactat ttgtaccagc agaaggcttt gacagactat tttaaaatgg acgataggat
    44881 agaagcctct ttttctttga agccccagct gacaaggctt gacaccagcg ctttttatgc
    44941 tgaaacagcc ttcctaaaag ggcagctcat tgcgctgctg attctggagc tgggcttgac
    45001 gccaagtgag atagcagggc ttcgtcttgc tgattttgac ctgggtcttc aggtgctaag
    45061 gttgcaatct cacagaggca ttcgtgtgat gaccttatca aaggccttgc tgccattttt
    45121 ggaaaaggca acagaagctc agcagctcta cctctttgat catgacgcca agcccttttc
    45181 aaggcaatgg ttttttaacc agctcagaga ttttttagag agcattggct gtgcggagct
    45241 ttcagcccag agtctgagag agcaattcat tttaaatgaa aaagcagccg gtaaatccat
    45301 cattgaggtg gctcagctgc tggggctaaa aagcccgatc accttagaaa aatattataa
    45361 gatgtaatgg atataaaagt aaaagatttt gaaggtcctc ttgatttact cttgcaccta
    45421 gtgtcaaagt atgaggttga tgtttaccag gtgcctattg tggaggtcat tgaacaatac
    45481 ttggcctata ttgagaccct gcaggcgatg cgcttggagc ttgctggaga gtacatgctg
    45541 atggctagtc agctgatgct catcaaaagc agacgactgc tgccaaagct ggtagacaag
    45601 gagcctgatg aggaggatct tgagcaagag cttttgggta agattgaaga atatagtcgt
    45661 ttcaaggctc tgagtcagga gttggccagc cagcatgaca agagggctct gcttttttcc
    45721 aagccaaagc aggagcttat ctttgagcag gccgtcctac aaaaggataa aacagtcatg
    45781 gatttgtttt tagctttttc acagttaatg gctgcaaagc aagaggcctt taaatataac
    45841 catacggtta ttgagcgaga tgattatcgt attgaggata tgatggagct tattgaagct
    45901 aggcttgagc tagagcagga gcttactttg acggatttat tgaagcattg tgatcatctc
    45961 aatgaggcca ttaccttgtt tttagcaagc ctagaattaa tcaaacggca gcttgttggt
    46021 attgagcaga catcacattt tggccagatt gttttgcgaa aggagatcca atgacctatt
    46081 tatctcagct ggaggccttg ctgtttgtcg caggagaaga aggactaagc ctacgtcagt
    46141 tggccagcct attagagtta acaccgacag ccttacagca gcagctcgac aagctttctc
    46201 agaaatacaa agaggataag gaatctggcc tgtgcttgat tgagtcctct aggacctata
    46261 agttagtcac caaagagtgt ctggctccct tgcttaaaga ctatgctaag gctccaatca
    46321 accaaacctt gtcacgagca agcctggagg ttttgtcaat tgttgcctat aagcagccga
    46381 ttactcggat tgaaattgac gagattcgtg gtgtcaattc aagtggtgcc cttagtaaat
    46441 tagtggcctt tggtttggtt caagaggctg gcaaaaagga agtgattggt cgaccaaatc
    46501 tttatgcaac aacagattac tttcttgatt atatgggtat caatcattta gaagagctgg
    46561 ttgatatttc ttctattgct gttgaagagc aagagacaac cctgttttaa aggcaaagag
    46621 gagcttgtct catttgcaga taggccttat gccctctact agaagagata acagtcctaa
    46681 caaggtatag tgcctgaaaa tcctattgtc gttatggaca gcggtctttt taggcatgct
    46741 attaataaga gtagacctgt ttaagctagt gagcttttac ccataggaga gtgactggtc
    46801 tgttggagct atcatcagat ttcctaataa gaaagagaga aggataatga gaattaacaa
    46861 atacatcgcc catgcaggcc ttgctagccg tcgtaaggct gaagagctga tcaagcgagg
    46921 gctggtgacc ctaaatggtc aggtgataac agatttagca actactgtta aatcaggcga
    46981 ccttgttgag gtagagggga ttcctattta caatgaagag aaggtttatt atctcctcaa
    47041 caagcctcgt ggtgtcatct caagcgtttc agatgataag gggcgtcaga cagtgattga
    47101 tttgctgccg caggttaagg agcgcattta ccctgttggt cgcttggact gggatacctc
    47161 tggcttatta attttgacca atgatggtga ttttacagat aaaatgattc acccccgtaa
    47221 tgaaatcgac aaggtttatc tggctcgtgt caagggagtg gtaactaaag aaagcctgcg
    47281 tcccttaaca cgtggtgtcg ttattgatgg taaaaaaaca aagccggctc gttaccgcat
    47341 tattcgtgtt gagcctgata aaaatcgctc tattgttgaa ctaaccattc atgagggccg
    47401 tcatcatcag gtcaagaaaa tgtttgaagt ggttggacac ttggttgata agctatcaag
    47461 gacacagttt ggcagccttg atgtcagagg cctaaagccc ggagaagcca gaaggctgag
    47521 caaaaaagaa gtcagccagc tacatcattt agcgagcaca cgaaaatgat caaagcccta
    47581 ctcattgctc ctgtcagagc ctatcagaaa tatatttctc ccttatttcc tccttcctgt
    47641 cgttatcagc cgacctgctc ggcctatatg attacagcta ttgaaaagca tggtgctaag
    47701 ggtgttttga tgggacttac cagactatta aggtgccacc cttttgccgc tggcggagaa
    47761 gacccggttc cagatacctt ttccttaaaa agacatttca taacgcatga aaaaatacag
    47821 gattttgacc aaaaaactga ttgacaatag cagttaaagt gctataatag cagttaagta
    47881 ttcgttggtt taaatcaaac ctgttatgat ttaagttagc gagtcaccgt caaccacatt
    47941 gtttgctgag catgactccg ggcagtgtgg tttttttgat gaaaagagta agcgggacaa
    48001 gcatgaaaca agaaatcatt aatagacaat atagggaaaa agatagtcaa aaccatgtgg
    48061 tgctctttca gccacaaatt ccacaaaaca caggaaatat tgctaggacc tgtgctgcca
    48121 ccaacacgcc tttacatatc atcaggccta tgggctttcc gattgatgac cgtaagatga
    48181 aaagagcggg gctagattat tgggataagc tagacattag attttatgat catctagatg
    48241 aatttttagc acaatgtgat gggagcttgc atgtgattag caaatttgct gatagggtat
    48301 actcagatga agcctacaat gatcgtcagt ctcattattt tttgtttggg cgtgaggata
    48361 ctggtctgcc tgagcccttt atgcgtcaat atgctgatag ggcactcagg attcctatga
    48421 atgatgagca tgtcagaagt ctcaatgtct ctaatgctgt ttgcatgatc gtctatgagg
    48481 cacttagaca gcaagccttt aagggcttag agcttagcca tacctatgag catgacaaac
    48541 taaaatcata ataagcatat cgcaaaacat cagttagatt gaagaagtat ccgtagggga
    48601 gcttcttcag tcttttttta ttgtattctt tgcttattaa ccaagcagtt gacacgaaaa
    48661 ttccaataga tcgtttaaag ccaataaaa
//
LOCUS       DARYXS010000004        47956 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.004, whole genome shotgun sequence.
ACCESSION   DARYXS010000004 DARYXS010000000
VERSION     DARYXS010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47956
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.004"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            34..1377
                     /locus_tag="TV193_000161"
     CDS             34..1377
                     /locus_tag="TV193_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEL1512404.1"
                     /translation="MKLKTLLAIAAGRTAQLILNKIGRGSTYPGRLALMWDKDILDTL
                     AKDYEIVVVTGTNGKTLTTALTVGILKEAFGEVLTNPSGANMMTGITSAFLSAKRKKT
                     GKPIAVLEIDEASLARVTTYIKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGASQAPK
                     ATILANGDSPIFASKDLVNPVKYYGFDTPKHEPRLAHYNTEGILCPKCEQILRYRLNT
                     YANLGDYTCLNCDFQRPKLDYKLTQLTSITHHSSAFVIDDQTYRINVGGLYNIYNALA
                     AVAVAEFFGISADQIKAGFNKSKAVFGRQETFSINGKACTLVLIKNPVGASQALEMLR
                     LADYPFSLSVLLNADYADGIDTSWIWDADFELINQMDITEINAGGVRHSEIARRLRVT
                     GFDEAKITSFDKLEGIMQAIENQEAEHAYILATYTAMLAFRELLASRHIVEKEMI"
     gene            1377..2165
                     /locus_tag="TV193_000162"
     CDS             1377..2165
                     /locus_tag="TV193_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEL1512405.1"
                     /translation="MTYTSLQSPENRDYQYDLHIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGAKVRVDIVSIGDTFDQDDYDIVFFGGGQDYEQAIVARDLPSKKEALAAYIHQNK
                     VLLAICGGFQLLGQYYIQANGLKINGIGVMGHYTLNQDNNRFIGGIKIHNDDFDETYY
                     GFENHQGRTFLSDDEKPLGRVIYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVSLA
                     YRLVTTALKEKYGSTVSLAAYDKILQHETSEEYADVKSKASFDS"
     gene            complement(2789..3778)
                     /locus_tag="TV193_000163"
     CDS             complement(2789..3778)
                     /locus_tag="TV193_000163"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEL1512406.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVDEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIEQHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTTEGAFDFKTFS
                     QPVIETLADLGVKANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKISVEAFSDKILVKMKETYPDMTEYVLS
                     EDELAKIQQSAEEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSVIKNLKIY
                     GDFFGIKDVQDIESLLIGCKYEYADVLERLQTIDTTQYFSRMTVEEVAKAIVA"
     gene            complement(4020..5789)
                     /gene="lpdA"
                     /locus_tag="TV193_000164"
     CDS             complement(4020..5789)
                     /gene="lpdA"
                     /locus_tag="TV193_000164"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEL1512407.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKIIRQAGETVPVTEVIGYIGAAGEAIDVSSPAAADVNVARTTEDL
                     QAAGLEVPKAPDQGSAPSAPKAELAADEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVE
                     KSEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTV
                     VKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGVQTIKGRNIILATGSKVSRINIP
                     GIDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVEVTVIEMADRIIPA
                     MDKEVSLELQKILSKKGMTIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRV
                     PQMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENA
                     MHGSTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASN
                     EAHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMEAELTVDELLLSIHGHPTFS
                     EVMYEAFADVLGEAIHNPPKRKK"
     gene            complement(5998..7407)
                     /locus_tag="TV193_000165"
     CDS             complement(5998..7407)
                     /locus_tag="TV193_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEL1512408.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAAGESVDNSTASSEKTTEIPVPTSA
                     EANTTTVPKEAASTAPQVASVANAPAFGEKVRATPAARKAASEMGIELNQVPGTGPKG
                     RIHKEDVEGFKGAQPKATPLARKIAADKGVDLAAVVGTGIGGKITKEDILAVLGAAAP
                     AVEKASIAEEKPAKELPEGVEIKKMSAMRKAISKGMTHSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGLAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLVVPVVHGADKMSLSEFVLASKDVIKKAQGGKLKATEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGIGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(7531..8529)
                     /locus_tag="TV193_000166"
     CDS             complement(7531..8529)
                     /locus_tag="TV193_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEL1512409.1"
                     /translation="MTETKLMALREAINLAMTEEMRKDDTIYLMGEDVGVYGGDFGTS
                     VGMIEEFGAKRVKDTPISEAAIAGAAIGSAITGLRPIVDLTFMDFITIALDAIVNNGA
                     KNNYMFGGGLITPATFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANEAKGL
                     LKSAIRDNNIVIFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDVTIVSYGRMLE
                     RVLQAAEELAADGINVEVVDPRTLIPLDKELIINSVKKTGKLMLVNDAYKTGGFIGEI
                     AAMVTESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVAKIKAAIVKMVNKGN"
     gene            complement(8609..9577)
                     /locus_tag="TV193_000167"
     CDS             complement(8609..9577)
                     /locus_tag="TV193_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEL1512410.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKVTGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIVVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MSKAVEHVRGGNGPAVVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMLKYRAYLT
                     GEGIATDEELDALQAQVKQEIDDAYEFAQNSPDPDISVAFEDVWVD"
     gene            complement(10083..11993)
                     /locus_tag="TV193_000168"
     CDS             complement(10083..11993)
                     /locus_tag="TV193_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1512411.1"
                     /translation="MIILQGNNIERSFSGEVLFQNLSLQVGERDRIALVGPNGAGKST
                     LLKILVGEEEPTSGEVSRKRDLTLSYLAQNSRFESDKTIYQEMLKVFAELRVDEQRLR
                     QMEADMASRSGQALDQLMSDYDRLSESFRLRNGFTYESDIRAILNGFKFDESMWEMKI
                     SELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLEHYLVNYQGALIIVSHD
                     RYFLDKVATITLDLTKNSLDRYVGNYSRFIDLKAEKLAAEEKHYDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKLERLDKPSSSRKSASMTFQIDKPSGNVVLQVTDAAI
                     GYNDHILAEPIHLDVRRLDAIAIVGPNGIGKSTLLKSIIGEIPLIKGTCHYGTNVETG
                     YYDQTQSHLTGSNSVLEELWRDFPTTAELEIRSRLGAFLFSGEDVKKSVAMLSGGEKA
                     RLLLTKLSMKKDNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEITEAGSTLYLGDYDYYVEKKAEREELARLAAADHVVETDVAEAAVTDYQLQKAS
                     QKEYRRLTRRFEEIEQTLEGLEAQAKAIEAQMLVSNDTTQLIDWQKELDQLNQKQETL
                     LLEWEDIAGQLE"
     gene            complement(12403..13188)
                     /locus_tag="TV193_000169"
     CDS             complement(12403..13188)
                     /locus_tag="TV193_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEL1512412.1"
                     /translation="MASISIEYHSEILAMERHVKVIYPDQSELSPEEQGYQDIPVLYL
                     LHGMGGNENSWQKRTNIERLLRHTNLIVVMPSTDLGWYTDTTYGMNYYQAIAEELPRL
                     LASFFPNMTTKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALHFSPEMLLQQG
                     IGELPYWQGVFGDLNAPDIKKHYLTSIAAESDGQTQLYAWCGYEDFLFEANEKAVAEL
                     RRLGLTIDYRKDHGRHEWYYWNQQLEALLDWLPIAYHKEERLS"
     gene            complement(13294..14955)
                     /locus_tag="TV193_000170"
     CDS             complement(13294..14955)
                     /locus_tag="TV193_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1512413.1"
                     /translation="MTDINIIALGGVREYGKNFYLVEINDSMFILDAGLKYPETEQLG
                     VDLVIPSLDYVIENKDKVQGVFLSHGHADAIGALPYLLAEVPVPVFGSELTIELAKLF
                     VKANNSTKRFKNFHVVDSDTEIEFKDGLVSFFKTTHSIPESLGVVIGTDKGNIVYTGD
                     FKFDQASREGYQTDLARLADIGKEGVLALLADSANATSNEQTASEAEVGEEMDKVIAH
                     ADGRIIIAAVASNLVRIQQVFDSAAAYSRRVVLTGTDAENIVRTALRLKKLVIADEKL
                     LIKPKDMSKFEDHELIVLEAGRMGEPINSLQKMAIGRHRHVQIKDGDLVYIVTTPSAA
                     KEAMVARVENLIYKAGGSVKLITQHLRVSGHANARDLQLMINLVKPKYLFPIQGEYRD
                     LAAHAHLAEEAGILPENIHIMKRGDIMVLDEDGFLHEGAVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSRDILRESAELVNTT
                     VGNYLQGDHFDWSELKGSVREELSRFLFEQTKRRPAILPVVMEVR"
     gene            complement(15165..15923)
                     /locus_tag="TV193_000171"
     CDS             complement(15165..15923)
                     /locus_tag="TV193_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512414.1"
                     /translation="MRKIIELIHATVEVNNGFDETKAILDDVSLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLLLSKGQIKLLGHDVTHLPAEKRASYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGERRGLSSRRISHYMADFADLVKRVGNGLENHLETPTGLLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSQALMALTDDFVAKDRLTALMITHHMEDALNY
                     GNRLIVMKNGKIIQDLDQKRKSQMTIADYYQLFD"
     gene            complement(15920..16789)
                     /locus_tag="TV193_000172"
     CDS             complement(15920..16789)
                     /locus_tag="TV193_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1512415.1"
                     /translation="MIISSVSQGLLWGILGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTLLNLGLNPILATLAAMLAGALAGFATGLLYTKGKIPTLLAGILVMTSCHSIMLMVM
                     GRANLGLHDIKRIQDYLPFAADTNVLVAGLVVATLVIFLLMYFLYTNIGQAYIATGDN
                     RDMAKSFGIHTDRMELMGLAISNALIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVVGSILYQFLISVVIALGFNTNYLKLFSAIILALCLMVPV
                     LKKAIIKEASLSR"
     gene            complement(16803..17798)
                     /locus_tag="TV193_000173"
     CDS             complement(16803..17798)
                     /locus_tag="TV193_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1512416.1"
                     /translation="MKHKGLIVTVIALFLMVAASLVLKEGKKQPQLASKRVVKVGILQ
                     LVTHEALDQIAQGIKDELKKHHQPEQKVSITLMNAEGDQSKIQTMSKQLVKTNDIVVG
                     IATPAAQGLAAATKTIPVVMSAISDPVGAKLVKHLDRPEANVTGLSNKVPVRQTVDLI
                     KEMTPQVKRVGVLYASSEDNSISQVKDFTALAEKQGLEVLAYAVPSTNEVTTTMSVMT
                     EKVDAVFIPQDNTIASAFSAVIVASNAAQLPVYSSVDTMVEQGSLASISQSQYQLGVE
                     TARQVLQLMAGKEVSEVPVEVVDDGKPFLNLKAARDLGLMISKDLLKRSDLTGKQ"
     gene            18150..19820
                     /locus_tag="TV193_000174"
     CDS             18150..19820
                     /locus_tag="TV193_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HEL1512417.1"
                     /translation="MSFDGFFLHHLTQELNHSIVNGRIQKVNQPFDNELVLTIRNHRQ
                     TYKLLLSAHPVFGRIQLTQTDFQNPQFPNTFTMIMRKYLQGAIIEGFEQIDNDRIIEM
                     TVSNKNEIGDAIKTTLIIEIMGKHSNIILVDRHENKIIESIKHVGFSQNSYRTILPGS
                     AYIEPPKTTAVNPFTISDIALFEVLQTQELSAKNLQKHFQGLGRDTAQELSSLLTTDK
                     LKRFRDFFQRPSQPSLTQTSFAPVAFSNTLKTFQNLSQLLDYYYHDKAERDRINQQAS
                     DLIHRVQNELEKNRSKLIKQEAELLATENAEDFRQKGELLTTYLSLVPNDQDSVELDN
                     YYTGQKITIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTQQTIAYFESVDYN
                     LSQATIDEIEDIREELIQAGFVKSRKHNKHHKRKKPEQYLASDGKTIIMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLSPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPIESKIQAMKCSPSASSS"
     gene            complement(19909..21147)
                     /locus_tag="TV193_000175"
     CDS             complement(19909..21147)
                     /locus_tag="TV193_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEL1512418.1"
                     /translation="MLNSEKMIASLEQQDLEQAESYFQRALQEDDAETLLALAEYLES
                     IGFLLHAKTIYLQVCEAYPEVNINLAQIAAEDNVIEEAFMYLDRIPEDSADYLSALLV
                     MADLYDLEGLTDVAREKLLQAAELSQEPIVIFGLAEIEMSLEHFSEAIEQYARLDNRH
                     ILELTGISTYQRIGRAYAYLGKFEAAVEFLEKALAIEYDDETVFELATILYDQAAYQK
                     ANLYFKQLETMNADFLGYEYPYAMSLREEHRTEEALRLVQQGLRKNAFDPQLLLLASQ
                     LAFELHDPAGSERYLLRAKEVAVDDEEVIMRLSSLYLDMERFEEVIALEHEEIDHVLT
                     KWNLAKAYQALEQQEKALTIYKDIEGDLKENPDFLQDYAYLLREFGYTDQAVKQAKRY
                     LQQVPDDIHMQGFLDDLRDD"
     gene            complement(21137..22318)
                     /locus_tag="TV193_000176"
     CDS             complement(21137..22318)
                     /locus_tag="TV193_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1512419.1"
                     /translation="MSLHSKPNHHDSLFYKWFLNNQAVMVLLITLLVFLTIFVFTKIS
                     FLFTPILSFLAIIMLPLVISTILYYLTKPLVDMVEKLGPNRTASIFIVFGLVILLFFW
                     AISGFIPMIQDQLRSFVEDLPKYVAKVNLEANKLLENEWLVSYRSNLQDMLTSMSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIMSPFILFYFLRDSGHMKNGLVNVLPIKL
                     RQPMARVLGEINKQLSGYVQGQVTVAIVVGLMFSVMFSLVGLNYSITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMGMVQGPLMLIKVLIIFVIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPVYASVKVVVKELFDWYKDITGLYEEEPTEAERVAEDV
                     K"
     gene            complement(22381..22857)
                     /locus_tag="TV193_000177"
     CDS             complement(22381..22857)
                     /locus_tag="TV193_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1512420.1"
                     /translation="MTKLATICYIDNGEALLLLHRNKKENDVHQGKWISVGGKLEPGE
                     SPDDCARREILEETHLLVKAMDFKGVITFPDFTPGHDWYTYVFKVTDFEGDLIADEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFRYDDHNKLVEKTVTFY"
     gene            complement(23035..24081)
                     /gene="rfbB"
                     /locus_tag="TV193_000178"
     CDS             complement(23035..24081)
                     /gene="rfbB"
                     /locus_tag="TV193_000178"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEL1512421.1"
                     /translation="MSEYKNIIVTGGAGFIGSNFVHYVYNHHPEVHVTVLDKLTYAGN
                     RANLEEILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIYTN
                     FVGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTADTNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILDKMGQPKD
                     AYDHVTDRAGHDLRYAIDSTKLRQELGWEPQFTDFSEGLEQTIQWYTDHQDWWRSEKE
                     AVEANYAKTQEVIR"
     gene            complement(24273..24869)
                     /locus_tag="TV193_000179"
     CDS             complement(24273..24869)
                     /locus_tag="TV193_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEL1512422.1"
                     /translation="MTEQFFDKALACREIEAIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MIPLGFPEQFFAAGKLQNNISFSRKHVLRGLHAEPWDKYISVADEGKVLGAWVDLREG
                     DSFGHTYQTVIDASKGIFVPRGVANGFQVLTDKVAYTYLVNDYWALELKQKYAFVNYA
                     DPSLGIAWESLEQAEVSEADKSHPFLEAVKPLRQEDLS"
     gene            complement(24869..25738)
                     /gene="rfbA"
                     /locus_tag="TV193_000180"
     CDS             complement(24869..25738)
                     /gene="rfbA"
                     /locus_tag="TV193_000180"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEL1512423.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDDEMNAISIEEK
                     PAVPKSHFAVTGLYFYDNDVVEIAKSIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYITKEDVYQLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(25795..26904)
                     /locus_tag="TV193_000181"
     CDS             complement(25795..26904)
                     /locus_tag="TV193_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEL1512424.1"
                     /translation="MTTIAIIGAGIVGSSAAYYLKKQGYQQVTIFDDGNGQATKAAAG
                     IICPWFSKRRNKAWYQLARLGADCYQDLIKELQKEGLSTHFYKQTGVYLLKKNEDKLE
                     ELYQLAIRRKQESPLIGDLAIRCRSDIRVDFPDLQGFEQLVWASGAARVDGADLCQCL
                     LEASGYQVVKKRVGISIEKQGYLVDGMVFDRLILAAGAWLPELLEPLGYQVDIRPQKG
                     QLIDYHIANVTTDNYAVVMPEGELDIIPFEHDRLSVGASHENDKGYDLEPDVAVLEAL
                     EQEALTYYPKLSSASDVSYRVGIRAYTRDFSPFFGQVPQLPGVYAASGLGSSGLTLGP
                     LIAQQLIALLLGQKASLDTSQYPIHHYIRRINDKK"
     gene            complement(26959..27747)
                     /locus_tag="TV193_000182"
     CDS             complement(26959..27747)
                     /locus_tag="TV193_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEL1512425.1"
                     /translation="MKARTIIEKYESYCPLELSMSGDVCGLQIGSLDKEVKRVMITLD
                     VRENTVAEAIAAKVDLIITKHAPIFKGLKDLVSSPQRDIVLELVKHDISVYVSHTNID
                     IVSDGLNDWFCELLGIEQTEVLVETQDGYGIGRVGNVAEQSLEELGLTVKEAFGLDVV
                     RLVRYTGQNPLISRVAICGGSGDKFYQAALAKGAQVYITGDIYYHTAQEMLTEGLLAI
                     DPGHHIESLFIDKLLAKMQAWKKEEGWQVTIMASKASTNPFSHL"
     gene            complement(27737..28423)
                     /locus_tag="TV193_000183"
     CDS             complement(27737..28423)
                     /locus_tag="TV193_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEL1512426.1"
                     /translation="MESHLSKRLRHVASYVPDGAKLLDVGSDHAYLPIFLVETEHIQE
                     AIAGEVVKGPFVSALKNVSQYGLTEHIEVRLANGLAAFEARDAVDCITICGMGGRLIA
                     DILAAGKEKLQGIERLILQPNNREDELRAWLSANAFCISAETIMTENGKYYEIIVAEP
                     GQQSLTDQEQRFGPFLSQERSSVFVAKWQKERDKLVYALSCVPATKPVERASISQKIK
                     AIEEVISHES"
     gene            complement(28497..29159)
                     /gene="nth"
                     /locus_tag="TV193_000184"
     CDS             complement(28497..29159)
                     /gene="nth"
                     /locus_tag="TV193_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEL1512427.1"
                     /translation="MRIGRERLKKVLSIIGEMFPEAKGELNWDQEKPFQLLITVILSA
                     QTTDKAVNKVTPKLWQSYPELSDLAQANVSDVEDHLRTIGLYKNKAKNIIKTAQQLLT
                     QFDGQVPKTHKELESLPGVGRKTANVVLAEIYGVPAIAVDTHVSRIAKRLNISAPDAD
                     VTEIEADLMAKLPKKDWIITHHRLIFFGRYHCLAKHPKCDTCPVQSYCSYYKTTYGKK
                     KV"
     gene            complement(29159..29836)
                     /locus_tag="TV193_000185"
     CDS             complement(29159..29836)
                     /locus_tag="TV193_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEL1512428.1"
                     /translation="MSFLEHYQSGNLVLPTALLFHYKDIFKSSDDFLVWQFFYLQNTT
                     RLDELAPSQIANALGKSVAEVNKAISSLTSQGLLDMKTIELAGEIEIIFDASPVLVTL
                     DQLLARDEKGEHEQQNTNQLKLLVDEFERELGRFLSPMELEDLEKTIHDDQTDLDLVR
                     EALREAVFNGKTNWKYIQAILRNWRKEGITSLRQLEEKKRAREDMTASEVTVSDDFLA
                     AMNLWSN"
     gene            complement(29903..30421)
                     /locus_tag="TV193_000186"
     CDS             complement(29903..30421)
                     /locus_tag="TV193_000186"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEL1512429.1"
                     /translation="MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYA
                     CDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIG
                     DYDCKVLMHFPG"
     gene            complement(30501..30869)
                     /locus_tag="TV193_000187"
     CDS             complement(30501..30869)
                     /locus_tag="TV193_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512430.1"
                     /translation="MRLWHQDLITRLPRQQLLGQHRECAALRGAGWGRPHATVDYVFA
                     HSLYKLYQYHLLIMQEMQARGYQPDVSWQDKNYRGKSLAAYEDLEEVALTSPIYPEHQ
                     EAYLQECLTNLKEKGIDLDD"
     gene            complement(30878..33088)
                     /gene="recJ"
                     /locus_tag="TV193_000188"
     CDS             complement(30878..33088)
                     /gene="recJ"
                     /locus_tag="TV193_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEL1512431.1"
                     /translation="MITSKYQWTIADKEPDAGFFKLAQAKGLSQTAAKLIYDRGVHTE
                     EELTSFLTADLSQLHDPYLLNDMEKAVHRIRQAIEGLERILVYGDYDADGMTAASIVK
                     ETLEMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEQVSLIITVDNGVSGHEAVAFAQ
                     AQGVDVIVTDHHSLPAELPDAFAIIHPEHPAAAYPFQKLAGCGVAFKLASALLETIPV
                     DFLDLVAIGTIADMVSLRGENRILVKNGLAVLKETERLGLQELMKLSEVDLAHFDEDV
                     ISFKLAPQLNALGRLDDPNPAIDLLTGFDDEELHELALMISSKNEERKVLVQEIFAQA
                     MAMLDLDKPVQVLAKSGWHPGVLGIVAGRIMEEIGQTVLVLTIDEGLAKGSARSLESI
                     NIFEALNSNRSLFTAFGGHEGAAGMTLPSDRLEELSELLCQYVAAKGHDGQEKNTLLI
                     NGELDLEALSIDSLNKLLLLAPFGMDNKKPVFYLKDFTIKQARTIGQQQSHLKFKVSK
                     GAVEADVLAFGQGHLIQEYQQSQGLELAVSLAINHWRGHTSLQLMLVDARVTGVQLFD
                     IRARTARAPEHIPTAVEDQQAKVVVIDEVPDDIDALKGLFRHREFEAIYFKNHIKRPY
                     YLTGYGSREQFAKLYKTIYQYPEFDLRHKLTLLSDYLKIEKILLVKMIQIFEELGFVV
                     IEDGLMRVKTDAPKRSIADSVIYQQLKELVKFQELMALGSPQEIYQYLMTSEEK"
     gene            complement(33085..33849)
                     /locus_tag="TV193_000189"
     CDS             complement(33085..33849)
                     /locus_tag="TV193_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1512432.1"
                     /translation="MAQRIILITGASGGLAQAIIRQLPREDYLILLGRSKDRLDSLYQ
                     ARGNKECYEIAIQDPAAIEALVDELYQRHGRIDVLINNAGFGAFKAFDDFSAEEIEAM
                     FRVNSLASIHFARLLGHKMAEQGSGHIMNIVSMAGLIASAKSSIYSATKFAVIGFSNA
                     LRLELAERQVYVTTVNPGPIATSFFEQADPSGQYLASVAGFTLQADTVAKKIIAAIGK
                     KKREINLPISLALAHKCYTLFPTISDYLARKVFNYK"
     gene            complement(33849..34778)
                     /locus_tag="TV193_000190"
     CDS             complement(33849..34778)
                     /locus_tag="TV193_000190"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEL1512433.1"
                     /translation="MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYV
                     TNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALRAVGVPFGPLFGKVKNGQDIELEDGTKIFAKDFISEPRKGKIITIIGDTR
                     KTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKVVRDLEEVII"
     gene            complement(34793..35431)
                     /locus_tag="TV193_000191"
     CDS             complement(34793..35431)
                     /locus_tag="TV193_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEL1512434.1"
                     /translation="MTDYIQLAKTYGGFTSLDTVYLQNCLKGLTDQQKLATITPPPSV
                     INAYFAEMYQKQSPKAATDYYFELSRALKLFTSEPSFDEVKPFVRLNLLGQSYGFVFE
                     NEAQEAIVFAEKEQGQPEESLLLELAQIFPQYVVYVEDGRIKMKSCQFEQGEPEDITP
                     EHALLTTIYRFSNEMTLLKGFNSDELLALSQAFKGKKYYQFAQREFMIYLVH"
     gene            complement(35424..36662)
                     /gene="hflX"
                     /locus_tag="TV193_000192"
     CDS             complement(35424..36662)
                     /gene="hflX"
                     /locus_tag="TV193_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEL1512435.1"
                     /translation="MIETKARQERVILLSVVLQAADHAELSMTELASLAKTAGAEVVD
                     CYLQKRERYDSKTFVGSGKLAEIKEMVAANEIDTVIVNNRLTARQNANLEDALGIKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGVMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLAAVEKNRQTIRDRRMTSDVFNIGLIGYTNAGKSTIMTIL
                     TGDKQYEADELFATLDATTKQIYLQNQFQATLTDTVGFIQDLPTELVAAFKSTLEESR
                     HVDLLLHVIDASDPNHLEHERVVLDILKDLDMLDIPRLAIYNKMDKTASLTATVFPNV
                     RLSARDKNSRSLLRQLLIDQIRDMFEPFSIKLCQDQAYKCYDLNRLALLEPYSFDKEI
                     EEISGYIAPKNKWRLEEFYD"
     gene            complement(36747..37637)
                     /gene="miaA"
                     /locus_tag="TV193_000193"
     CDS             complement(36747..37637)
                     /gene="miaA"
                     /locus_tag="TV193_000193"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEL1512436.1"
                     /translation="MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHL
                     DIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIR
                     SLELNQFARDLENQEAPYNPLIIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQ
                     YPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSI
                     SESSYPQAIYDRVERFLKEP"
     gene            37770..37946
                     /locus_tag="TV193_000194"
     CDS             37770..37946
                     /locus_tag="TV193_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEL1512437.1"
                     /translation="MAKKHGFAKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFV
                     EENRKKAARRRVAR"
     gene            complement(38102..38739)
                     /locus_tag="TV193_000195"
                     /pseudo
     CDS             complement(38102..38739)
                     /locus_tag="TV193_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            complement(38896..41160)
                     /gene="glgP"
                     /locus_tag="TV193_000196"
     CDS             complement(38896..41160)
                     /gene="glgP"
                     /locus_tag="TV193_000196"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEL1512438.1"
                     /translation="MKRFTDYTEMTLGKSLASASNEEIYLSLLSYLKEEASKKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFRHNEQTAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTDIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEALERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTQKHGFDFDEAVSVVQKMDGYTNHTILAEALEKWPLDFLNEVVPQ
                     LVTIIEQLDALVRARVSDPAVQIIDETGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQELADYIKELIGDAYLTDATRLEKLMAFA
                     EDQAVHARLAEIKHHNKVALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYATGGYVSKDYYDAHPAIKEAVNFIISPELLELGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIAVKEQMLADYDNQDLWLTKVVHNIAKAGFFSSD
                     RTIEQYNQDIWHSY"
     gene            complement(41186..42688)
                     /gene="malQ"
                     /locus_tag="TV193_000197"
     CDS             complement(41186..42688)
                     /gene="malQ"
                     /locus_tag="TV193_000197"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEL1512439.1"
                     /translation="MTKRASGILMHISSLPGRFGIGSFGKEAFEFVDFLKETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDLELLAKDGYLQEADYAAVDFGSNPESVDYA
                     QVFQARRPLLEKAVQAFVSTEEGLRQLAEFEATASWLNDFAEFMAIKEHFDHKALQEW
                     DDRAIVKREEAALLHYRKLLAKGITYHKVCQYFFYQQWLALKTYANQNGITIIGDMPI
                     YVSADSVEVWTMPELFKVDADKKPIYIAGVPADGFSEDGQLWGNPIYNWESHEQTGFA
                     WWIHRIKESFKLYDKLRIDHFKGFSDFWEIPGGDVTAKNGHWESAPGIALFKAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDVTSQSFDLPHNYDHNCIVYT
                     GTHDNEVVNGWYEHLSAEQVEFVNHYIHKAAAESITKAMLRTIFATVCDTAILCMQDL
                     LDKSADSRMNMPNTVGGNWQWRMLEDDIKAEHKAYLIHLTELYGRANNHH"
     gene            complement(42896..43918)
                     /locus_tag="TV193_000198"
     CDS             complement(42896..43918)
                     /locus_tag="TV193_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1512440.1"
                     /translation="MVTIKDVALKAGVNPSTVSRVLKDNRSISQKTKEKVRRAMSELG
                     YVPNVAAQMLASGLTHNIGLVFPPIITNDRLSDPFFMEILSTITNEAKKHHFTVSIAT
                     GMSVEDLLSQVKLMHLQKRVDGFIILYSEQEDPVRGYLMTNQIPFVIVGAPEGDENKI
                     TYIDNDNQLMAKTAVDHLYQKGHRQILFITDDMEAEVASERYIGYLKGCLKLSLENKP
                     MLLFDRKDPISIEKVIETIRSFKATALIVIGDVLSVRMVQLLSFYDIKVPDDISIITF
                     NNSSYSKLIHPYLTTFDINVENLGRTSFRQLLDIINANEQTLSQKILVPFSLKKRESV
                     RDINAK"
     gene            44165..45418
                     /locus_tag="TV193_000199"
     CDS             44165..45418
                     /locus_tag="TV193_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1512441.1"
                     /translation="MKSWQKVIVSGASLTLASALLVGCASGSKDKTETASGTDSKTIK
                     LWVPTGAKKSYTDVVAKFEKDSGYKVKVIESEDPKAQEKIKKDASTAADVFSLPHDQL
                     GQLVESGIIQEVPEEYTKEIADTATDQAILGAQYKGKTYAFPFGIESQVLFYNKTKLA
                     ADDVASYDTITSKATFGGTFKQANAYATGPLFMSVGNTLFGESGEDTKGTNWGNEKGV
                     AVLKWISDQASNKGFVNLDANNVMSQFGDGSVASFESGPWDYEAAQKAIGKENLGVAV
                     YPKVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKT
                     RNIVPANKTVQASEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDA
                     FNGKIKEGDYLAKLQQFDKDIAATK"
     gene            45718..47079
                     /locus_tag="TV193_000200"
     CDS             45718..47079
                     /locus_tag="TV193_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1512442.1"
                     /translation="MTQAGLASQVTVKEALTKGSFDIKLSAIIMGFANFANKQFVKGT
                     LFLLSEVVFFIAFVSQIIPAIGGLITLGTQTQGMTTKTIDGISIQVAVDGDNSMLMLI
                     FGLASLIFCLLFAYIYWCNLKSARHLYMLKQEGAKIPSFKEDFVSLANGRFHMTLMTI
                     PLIGVLLFTVLPLIYMICLAFTNFDHNHLPPKSLFDWVGLSNFGNVLSGRMAGTFFPV
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKLKKMWRTFFVITIAVPQFISLLIMRN
                     LLNDQGPLNALLSKLGLIHHSLPFLSDPIWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILIIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSAYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            47079..47915
                     /locus_tag="TV193_000201"
     CDS             47079..47915
                     /locus_tag="TV193_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1512443.1"
                     /translation="MKNKRRFQLGLVYAILTVLSIIWLLPIAWVVLTSFRAEGTAYVD
                     YFLPKHLTLDHYIKLFTNETFPFGRWFVNTFVVAIFTCIISTFITVAMAYSLSRIKFK
                     FRNRFLKLALVLNMFPGFMSMIAIYYILKALGLTQSLTALVLVYSAGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLSKPIIVYTALLAFMGPWVDFIFAQVILG
                     DATSRYTVAIGLFSMLQPDTINDWFMAFTAGSVLIAIPITLLFMFMQKYYVEGVTGGS
                     VK"
BASE COUNT        13861 a        11414 c         9066 g        13615 t
ORIGIN      
        1 ctaaaattta agaacttatg ttaaaatatt aacatgaaac taaagacact actcgctata
       61 gcagccggaa ggactgcgca gctcatttta aataaaatcg gaagaggctc aacctacccc
      121 ggacgattgg ccttgatgtg ggataaggat attttagaca cacttgccaa ggactatgag
      181 attgttgttg tgacagggac aaatgggaaa accttaacca cagctctaac tgttggtatc
      241 ctaaaagaag cctttggtga ggttttgact aatccaagtg gcgccaacat gatgacaggg
      301 attacctctg cctttttatc tgctaaaaga aaaaaaacag gcaagcctat tgccgtctta
      361 gagattgatg aggcaagcct tgcaagggta acaacataca ttaagccaag tctttttgtt
      421 tacactaata tctttcgaga ccagatggat cgctacggtg agatttacac cacctatcag
      481 atgattgttg atggtgctag tcaagcgccg aaggcaacca ttctagctaa cggtgatagc
      541 cctatctttg cctcaaagga cctggttaat cctgttaaat attatggctt tgacacacct
      601 aagcatgagc cacgcctagc tcactacaac actgaaggca ttttgtgccc aaaatgtgaa
      661 cagattctcc gttatcgtct caacacctat gctaatctag gagactatac ctgcttaaat
      721 tgtgatttcc aaaggcctaa gttggattac aagctaacgc aattaaccag cattacccat
      781 catagctcag cctttgtgat tgacgatcag acttatcgca taaatgttgg aggactctat
      841 aacatctata atgccctcgc agctgttgct gttgctgagt tttttggcat ttctgctgat
      901 cagattaagg ctggcttcaa taaaagcaag gctgtttttg gtcgtcagga aaccttctcc
      961 atcaacggta aagcctgtac gctggttctc attaaaaacc ctgtgggtgc tagtcaggca
     1021 ctagaaatgc tgcgcctagc cgattatccc tttagcctat ctgtgctttt aaatgctgat
     1081 tatgctgacg gtattgacac aagctggatt tgggatgctg attttgaatt gattaatcaa
     1141 atggacatta ctgagatcaa cgccggtggg gttcggcatt ctgaaattgc aagacgctta
     1201 cgagtgacag gctttgatga ggctaaaatc acatcattcg ataagcttga aggtatcatg
     1261 caagccattg aaaaccaaga ggctgagcat gcctatatcc tagcgaccta tactgctatg
     1321 ctagcatttc gtgagctgct tgccagccgc cacattgtcg aaaaggagat gatctaatga
     1381 cctatacctc gctacaatct ccggaaaatc gcgattatca atacgacctt catattgctc
     1441 acctttatgg taatttgatg aatacctatg gcgataacgg caatgtcttg atgttgaagt
     1501 atgtcgctga aaagctaggc gctaaggtta gagttgatat tgtatccatt ggggatacct
     1561 ttgaccaaga tgattatgac attgttttct ttggtggtgg tcaagattat gagcaagcca
     1621 ttgttgctag agatttgcca tcaaaaaaag aggccttagc agcctatatt caccaaaata
     1681 aggtactcct tgccatttgt ggtggctttc agctgctggg acagtactat attcaagcca
     1741 atggccttaa aatcaatggc attggggtta tgggacatta taccttaaac caagataata
     1801 accgctttat cggaggcatt aaaattcaca atgatgactt tgacgaaacc tactatggct
     1861 ttgaaaatca tcaaggacgg acctttttat ctgacgatga aaagcctctt ggacgtgtca
     1921 tttatggaaa tggtaataat aaagaggacc aaactgaggg cgtccactat aaaaacgttt
     1981 acggcagcta ctttcatgga ccaatccttt cgcgtaatgt cagcctggcc tatcgcctag
     2041 tcacaactgc tctcaaagaa aaatatggct cgactgtttc cttagcggcc tatgataaga
     2101 tcttacagca tgagacctca gaggaatacg ctgatgttaa aagcaaggct agctttgaca
     2161 gttaagtcct tctcatagcc tgattaaacc acaacagaca tgcaaaacag ttattcccga
     2221 atgaaaatat agatttaaat agacaccctc aatgtttttc ctatcataaa atccataaaa
     2281 gataagacat attcttgcaa taactgaaca ttgaaagaca gaaagctttc tgtccttact
     2341 aaacatcttt catgcgtctg tcgtgctgat caagcgagat aaccccaaaa aagtgctagc
     2401 acagtaacaa aatggctatg accatatgtc tgtgcagctc tactgtcact gcatagacag
     2461 gctagagggg acgccctact tggttcagcg atctaggggt aggtctagct tgtttgtgct
     2521 gagtctgttt cggtagcaaa gattgaatcc tgctataaga tactctcaaa aagattaacc
     2581 caaaagcctt gcaacacatt taacgttttt agggataagt accgatatgc agacacatag
     2641 caggagatct atgtgtctgg taccaaagga cacaaaaaac taaagtaaca cactaaaagc
     2701 cacatgatac ccatttgata gggggcgtca tgtggctttt ttctatctca ctgttcatta
     2761 caaaaagcca aaccagcttc tttttgcatt aggcaacaat ggcctttgcc acctcttcta
     2821 ctgtcatacg tgagaaatat tgtgttgtat caatggtttg aagacgctca agcacatcag
     2881 catactcgta tttgcaacca atgagtaggc tttcaatatc ctgcacgtcc ttaataccaa
     2941 agaaatcacc gtagatctta agattcttaa taacagaatt ttcaacatta gcaaaggttg
     3001 agattttacc ggcagggtag cgaacattac gttcaatcgt gtattcaggt gcctttccat
     3061 aggtccaatc ccagctccca aattgctcct cagccgattg ttgaatctta gccagctcgt
     3121 cctctgacaa gacgtattct gtcatgtctg gataggtctc cttcatttta accaaaatct
     3181 tgtctgaaaa tgcttctacg ctgatttttt ctggcagctc atttaaaata ttggtcacgc
     3241 gggctcgtac agatttgact cctttggact caatcttatc cttactgacc ttgagcgcat
     3301 caccaagaac agtcatatcc acatcaaaca agagacagcc atgatgcatc atacgtccct
     3361 tataataggc ttgagcattg ccacagattt tcttgccatc aatttcaatg tcattgcgac
     3421 ctgtaaaatt agccttaact cctaaatcag ccaaggtctc aataactggc tgtgagaagg
     3481 ttttaaaatc aaaggctcct tctgttgttt tattggaaat aatcgtgtag ttaaggttat
     3541 tgagatcatg gtaaactgca ccaccgccag acaagcgacg aaccacatga ataccatgct
     3601 gttcgatgta ctccttgttg atttcctgaa tggtattttg atgcttacca ataataatag
     3661 ccggctcatt gatccagagg ataaacaatt catcctcatc aaccaattct ctaaaggcat
     3721 aagcctctag agcaatgtta aaggcagggt tgtggctctt attaacaatg tatttcattt
     3781 ctatctccta tagcgataat cgttatcata ttctattctt tattctaatg gaaactctta
     3841 caaaagacaa gctaaaagag gctagcaaaa gcaagggaac tagtaaatgc ttcctcaatc
     3901 aagaaccatc tgcaagctag cagtaaagct tgatctaact taaagagcct tccttgtatc
     3961 aacgaaagag ctgagaaatc tttttcccag ccctttttta tcgcagctat atagctagct
     4021 tattttttac gttttggtgg gttatgaatg gcttcgccaa gcacatctgc aaaggcttcg
     4081 tacatcacct ctgagaaggt tgggtgtcca tgaattgaca atagcaattc atcaactgtt
     4141 agctcagcct ccatgattgt ggctgcttca ttgatcattt cagcggctgc tggaccaatg
     4201 atgtgaacac caagtatttc atggtattta gcatctgcaa taacctttac aaagccatga
     4261 gcctcgtttg acgcaatagc acgaccattt cctgtaaagc tatttttacc aataagaaca
     4321 tcgccatatt gctcacgagc ctgctcttca gttaaaccaa ccatagcgac ctcagggtga
     4381 gtatagaccg ccgctggagt gtattttagg ttagccttac gtgttgtgct gccatgcatg
     4441 gcattctcag cagccacctc acccatacgg taagcagcgt gggcaagcat tttagtgccg
     4501 ttaacatcac ccggtgcata aatgcctggg attgacgttt cttggtagtc attaacctta
     4561 atgcggttac ggtccatttc aaggttgagg ttttcaagac cattcatctg tggcacacgt
     4621 ccaatagata gcaaggcctt ttcagcaaca acctcttcgc cattattaag cttcaaggtc
     4681 aactggttgt tggcttcaac aatctcagag acaccaactg aggtctttat tgtcatgcct
     4741 ttcttagaaa ggattttttg aagctccagt gaaacctcct tgtccatggc aggaataatg
     4801 cggtcagcca tttcaataac tgtaacctct acaccgtaag aggcccaaac aagaccaagc
     4861 tcaataccaa caacaccacc gcccataaca gcaagtgatt tcggcatttc acgcaaatca
     4921 agaatatcat cagatgtcaa gacaagctta gaatcaatcc ctggaatatt gatgcgtgag
     4981 accttagagc ctgtcgcaag aataatattg cgccctttaa tggtttgcac accaatggta
     5041 accgttttat caggatttac ctgaccaagg ccattaaaga tggttacctt gttggcttta
     5101 agaagccctt gaaccccacc tgttagcgtc ttaacaaccg tatttttaaa gtcaactgtc
     5161 ttatccatgt caatagtata gttggttgaa gcaaggttaa tcccgcgtcc tgctgcaatc
     5221 ttgatgccat caaggatttc agcatttttg aggtaggttt ttgttgggat acagccaacg
     5281 tttaagcagg taccgccaaa ttcagatttt tcaacgatag caatcttgcc gcccagctga
     5341 gcaccacgaa tagcagcgta gtaacccgca ggaccgccac cgacaacaat gatgtcatat
     5401 tcatcagcag caagctctgc ctttggtgct gatggcgctg atccttgatc cggtgccttt
     5461 ggcacctcaa gaccagccgc ctgtaaatcc tcggttgtac gcgcaacatt gacatcagcc
     5521 gctgctgggc ttgatacatc gatagcttca cccgcagctc caatgtagcc gataacttcg
     5581 gttacaggga ctgtctcacc tgcctggcga atgattttta aaagcacacc tgagtcttct
     5641 gcttctaatt ccatattggt cttgtctgac atgatttcca gaagaatgtc accctcgctg
     5701 acagtgtcac cctcctgctt tttccactcg atgatctcgc cttcttgcat gtcaacaccg
     5761 agctttggca taataatttc aacagccata atgatattgt aaggaacgtt caaatgcaat
     5821 cagatgcctt aacaatcagc actggctaac ataagcctgc taaaagccct gcatttagct
     5881 catagctagt gactacgagc tcgttccaga tcctttctat agttttaaag aattatcttt
     5941 tcgttacttt gtttctgaaa tatgctctct ttgcatcgca ggccataagg cctgtcatca
     6001 gattagcagt tcaaatggat tttccatcaa ttttttgaga tcaaccatga atttagcacc
     6061 attcatgccg tccaccagac ggtggtcaat tgtcagacac attgccatga ttggacgtgc
     6121 aacaatctca ccatcgacca ctgttggggt tggaatggtt gccccaatac ctagaatagc
     6181 tgaattaggc tgattgataa ttggattgaa ggttttggtg ccaaacatac ccagatttgt
     6241 gatggagaag gttgagcctg acatttcggt agcctttagc ttgcctcctt gagccttttt
     6301 gataacgtcc ttagaagcaa ggacaaactc tgagagactc atcttatctg caccatgaac
     6361 aactggcaca actagcccat catcaagtcc tacagcaata ccaaggttga caaagcgatg
     6421 aagctcaata tcattagcat cattaatcaa tgacgcattc atgtattcgt gctctggctt
     6481 catcaaggtc ttaacaacgg ctaaaccaat caagtcagta aagctaacct ttagccctgt
     6541 tttagccatg attgggtcaa tcagcttctt gcgcaaggca atcatttcgg tcatgtcaat
     6601 gtcataatta agcgtaaagg ttggtgctgt aaggtaggaa tgtgtcatac cctttgaaat
     6661 agccttacgc atagcagaca tcttcttaat ttcaacaccc tctggaagct ccttagcagg
     6721 cttttcttca gcaatagatg ctttttccac agcaggtgct gctgcgccaa gcacagccaa
     6781 aatgtcctcc ttggtaatct tgccaccaat acctgttccg accaccgctg caaggtcaac
     6841 tcccttgtcg gcagctatct tacgagcaag tggcgttgcc ttaggctgag ctcctttgaa
     6901 gccttcaacg tcttctttgt ggatacggcc ctttggtcct gttcctggca cttggttaag
     6961 ctcaattccc atttctgaag ctgctttacg agctgctggc gttgcgcgta ccttttctcc
     7021 gaaggctgga gcattggcaa ctgatgctac ctgaggcgct gttgaggctg cttctttcgg
     7081 tacagttgtt gtattagctt ctgctgatgt tggtactgga atttcagttg ttttctcact
     7141 tgaagcagta ctattatcaa cagattcacc tgcagcacca atatagccga taacctcagt
     7201 gacagggact gtttcacctg cctggcgagt gatttttaga agcacacctg aatcctctgc
     7261 ttcaagctcc atatttgtct tgtctgacat gatttcaaga agaatgtcac cctcgctaac
     7321 agtgtcaccc tcctgctttt tccactcgat gatctcgcct tcttgcatgt caacaccgag
     7381 ctttggcata ataatttcga cagccatata tttcctttca tttaatcccg cagcccatga
     7441 tcttaagacc agatacagct gctgaaaaaa gggatactgt tttatcagcc tgatgaagaa
     7501 agcctctaag ctaagacttc ctttgccatg ctaatttccc ttgttgacca tttttacaat
     7561 agcagccttg attttagcaa catctggtaa gatagcttgc tcaagaacac gtgcataagg
     7621 tactggtacg tcctcactag caagacgcac aattgggtga tcaaggtaat caaaggcttc
     7681 actttcagtg accattgctg caatctcacc gataaagcca ccagtcttat aggcatcatt
     7741 aacaagcata agcttccctg tcttcttaac agaattaata attaattcct tatctagtgg
     7801 gataagggta cgtggatcaa caacctccac attaatacca tcagctgcaa gctcttcggc
     7861 tgcctgaagg acacgctcta gcatacgccc ataggaaaca atggttacat cagtcccttc
     7921 acgcttgata tcccccttgc caagtgggat ataaaaatct ggatcctgat tgacctcttc
     7981 ttttttaccg tacaaggcct taggctccat gaaaataaca atattgttat cacgaatagc
     8041 tgactttaaa agtccctttg cttcgttagc agttccaggt gcaaccacct tgatcccagg
     8101 aatatgcgtc aaccaagcct caagagattg cgaatgctga gctgcagatc caattcctga
     8161 gccagaagca acacgaaaag ttgctggcgt gatcaagcca ccaccaaaca tgtagttgtt
     8221 ttttgcccca ttattaacaa ttgcatcaag tgcaatggta ataaagtcca taaaagtaag
     8281 gtcaacaatc ggacgaagcc ctgtaattgc tgaaccaatc gctgcacctg caatagcagc
     8341 ctctgaaatc ggcgtatcct tgacacgttt ggcaccaaat tcctcaatca tgccaacaga
     8401 agtaccaaag tctcctccgt aaacacctac gtcctcaccc ataaggtaaa tcgtgtcatc
     8461 tttgcgcatc tcctctgtca tggcaagatt gatagcctca cgcaaagcca ttaattttgt
     8521 ttctgtcatt attatctcct aatgtttaca aaatagaatt gtcaatgtta ctgtgaatag
     8581 atttttgctc gatgtgctag cagatcagct agtctaccca aacgtcctca aaggctacag
     8641 aaatgtctgg atctggacta ttttgtgcaa actcataagc gtcatcaatt tcttgcttga
     8701 cctgtgcttg aagcgcatct aattcttcat ctgtagcaat gccttcacct gttaggtaag
     8761 cgcgatactt aagcattggg tccttttcct tccactcatc aacctcttct ttggtgcggt
     8821 atttgccggc atcagcagtt gaatgaccaa accaacggta agactcaacc tcaacaacag
     8881 caggaccatt gccaccgcga acatgctcaa cagccttact catggtttca taaactgcca
     8941 tcacatcgtt gccgtcctca caataaaagc ctggaatacc ataagcctca gcacgcgtgt
     9001 agaggtgagg tgtatttgtg gcattgttaa tgctcatgga aatcccatag cggttgttaa
     9061 tgataaagaa aatcacagga agcttccaag ttgctgccat attgacagac tcatggaagg
     9121 agccctcatt tgttgcgcca tctccagaaa aggccacaac gatattgttg gtccccttgt
     9181 attgctgtgt caaggcagca cctaccgcaa gggcatagcc acctccaacg ataccatttg
     9241 ttccatagtt tcctttttca aaatcagcca agtgcattga gccgccgcgt ccctttgaca
     9301 cacctgttac cttaccggct agctcagcca tcattttatt gaggtccata tctttagcaa
     9361 tagattgccc atgcccgcgg tggtttgaaa aaataatatc atcataggtc aaatgtgcca
     9421 cagcgccaac gtttgctgcc tcctcaccaa ctgagaagtg tgtcatgccc tgcacaaatc
     9481 cacgacggac aagcttatta atacgtgaat caaattcacg aatacgctcc attttaagga
     9541 acatatctaa atgttgttct ttagaaactg ttaccatttc ggcctccata ttatcatatt
     9601 acttcctaat cataaaactt ttcttcacaa tttgcaagga ttttaatcgc tttctttgtg
     9661 actataaaag cttttttaag acgttttagt ttgtggtttc acaagctaga ttgttatagc
     9721 atctgttaca tttatatata acagattgaa aaatgagtca gtgtttattc agggaggtca
     9781 agcacctatt gactttgata gtcagaaata tcatcactct ttaagaggaa aataggctct
     9841 aaatgacctg tttcttctag cacaatcatg atcacctacc aaacgaacgc tttgcttgcc
     9901 tcgctccgat agaggcgaaa tgaactaaaa atcgcataac taaaaatgcc tgattttacc
     9961 tgaaaatcag acatttaaaa gctttaagac attagactca ggctctaatt ataatcctct
    10021 aagaaaagcc tgctaccttg cactacccaa gaatagcaag gcaatttcat tatctcacca
    10081 ggctactcca gctgtcctgc aatgtcctcc cactccagca gcaaggtctc ctgtttctga
    10141 ttaagctgat ccaactcttt ttgccagtct atcagttgag tcgtatcatt tgatactagc
    10201 atttgagctt ctatagcctt agcctgtgct tctagccctt ctaaggtctg ctcaatctcc
    10261 tcaaagcgcc ttgttaagcg acggtattcc ttttggctgg ccttttgaag ctgataatca
    10321 gttacagcag cttctgctac atcagtctct actacgtgat ctgcagcagc tagacgggct
    10381 aattcctccc gctctgcctt tttttctaca taatagtcgt agtcccccag atagagtgtt
    10441 gagcctgctt cagttatttc taaaacctta gtggccactc ggttgataaa atacctgtca
    10501 tgactaacaa acaacaaggt cccatcaaag tcaatcaagg cattttctag aacctctttg
    10561 ctatcaatat ccaggtggtt ggttggctca tctagaatca gaaaattgtc ctttttcata
    10621 gataattttg ttaagagcag ccgagccttt tcgcccccag atagcatggc cacagacttt
    10681 ttgacgtcct caccagaaaa gagaaaggca cctaagcggc tgcggatctc aagctcagct
    10741 gtcgttggga aatcacgcca aagctcctcc aatacagaat tactaccagt cagatgagat
    10801 tgcgtttggt cataatagcc tgtttcaaca ttagtcccat aatggcatgt ccctttaatc
    10861 aaaggaatct ctccaataat ggatttgagt agggttgact tgccaatacc atttggccca
    10921 acaatagcga ttgcatctaa cctacggaca tctagatgaa ttggctcagc taaaatatgg
    10981 tcattgtagc caatagcggc gtctgtcacc tgcaaaacaa catttcctga gggcttatca
    11041 atctgaaaag tcatactagc tgatttgcga gagctacttg gcttgtctaa gcgttctagc
    11101 ttttctagct gcttgcgtct tgcctgagca cgcttggtcg ttgacgctcg aacaatgttt
    11161 ttttggacaa aatcctctag cttagcaatc tctttttgct gcttgtcata atgcttctct
    11221 tctgctgcaa gcttttcagc ctttaaatca ataaagcgtg agtaattacc aacatagcgg
    11281 tctaagctat ttttagtcag atcaagtgtg atggttgcga ccttatccaa gaaatagcgg
    11341 tcatgactga caatgatcaa ggctccctga taatttacca gataatgctc cagccaggca
    11401 atggtttcaa tatctaaatg gttggtcggc tcatcaagca ccaatagctc tggcttttct
    11461 agtagcattt ttgccagggc caaacgggta ttttgcccac cagaaagctc tgagattttc
    11521 atttcccaca tgctttcgtc aaacttaaag ccatttaaaa tagctcgaat atctgactca
    11581 taggtgaagc catttcgcaa gcgaaagctt tctgacagcc ggtcatagtc tgacatgagc
    11641 tggtccagag cttgccctga tcgactggcc atatcagcct ccatttgcct tagtcgctgc
    11701 tcatcaaccc tcaattcagc aaataccttt agcatttcct gataaatggt cttgtcagac
    11761 tcaaatcggc tattttgtgc caaataagat agggttaagt ccctttttcg actaacctca
    11821 ccgctagttg gctcttcttc tccaactaaa atcttaagaa gggttgattt gccagcacca
    11881 tttggcccaa ccaaggcaat gcgatcacgt tcaccaacct gcagcgatag gttttgaaaa
    11941 agcacctctc ctgaaaaaga gcgctcaatg ttatttcctt gtaatataat cataccctta
    12001 ttgtagcaaa aaaatgccct tttggggggc acttttagtt atttttacag gtaagataag
    12061 actcatcaac aagctaaaga cataagcctt aggctaacat cgcttatcac ccttagtggt
    12121 atttatctga tgagacaaac tgctgcttga aaaaccagtg ggttgacctg ttagcgtatc
    12181 caacaatcgc accacctgct cagttatgct tgaaatgcta ttagccagtg aggaatcact
    12241 atggttcgaa taataaatca aaccaaaaat aagcaatacc aatactatta gggtctgcaa
    12301 acagcctctg acaagctgcc agacaagctt cagcagaagc tttgggaggc ataagaggat
    12361 agtcagtagt tttttcatcg taataagcct aaattctttc gtttaggata gcctttcttc
    12421 cttgtggtaa gcaatcggca gccaatctaa tagggcctct agctgctgat tccaataata
    12481 ccattcgtgc ctgccatgat ccttacgata atcaatagtc aagccaagcc ttctcaactc
    12541 agcaactgcc ttttcattgg cttcaaacaa aaagtcctca tagccacacc aagcgtatag
    12601 ctgggtttga ccatcacttt ctgctgctat acttgtcaaa taatgctttt tgatatcagg
    12661 agcattcaaa tctccaaaaa caccctgcca ataaggcagc tcacctatac cttgctgtaa
    12721 tagcatttcc ggcgaaaaat gcaaggcccc agaaaaggaa gcagcatagg aaaagcgatt
    12781 gctttttaag gcccatttaa aggcaccata gcctcccatt gacagcccag caacaaaggt
    12841 tttttcacgc ttagtggtca tattaggaaa gaaagaagct aatagccgag gaagttcctc
    12901 tgcaatagct tggtaataat tcataccgta ggtggtatcg gtataccagc ctaaatcagt
    12961 cgatggcatc accacgatta aattggtatg gcgaagcagc ctttcaatat tagtccgctt
    13021 ttgccaggaa ttttcatttc ctcccatacc atgtaacaga taaagaactg gaatatcttg
    13081 gtagccttgc tcttctgggc taagctcaga ctgatcaggg tagatcacct tgacatgtct
    13141 ttccatagcc aagatctctg aatgatactc aatgctaatg cttgccatca gctcacctcc
    13201 tttttaatat caccaaagca taaggaaagc ccactcttaa gacctaaaag ccagatccta
    13261 tttgaccagc ttttaggcag ggctgtatct gtattaacgg acctccataa caaccggaag
    13321 aatagctggc cgacgcttgg tctgctcaaa taaaaacctt gagagctcct ctctaacaga
    13381 gcctttcaat tcactccaat caaaatgatc cccttgcaga taattgccaa ctgttgtgtt
    13441 gaccaattca gcactttctc gtaaaatatc tctgctcttt ttcacataga caaatccgcg
    13501 agtgttgacc ttagccttag agataatacg tttttccttt ttagatactg tgatcgcaac
    13561 aataaaaata ccgtcctctg ataagacctt acggtctctc aaaacaatat tgccaacatc
    13621 accaatggca tttccatcaa tcatcacatc actagcagga accgcaccct cgtgtaagaa
    13681 gccatcctca tcaagcacca tgatgtcacc acgcttcata atatgaatat tttcaggtag
    13741 tataccagcc tcctcagcta aatgagcatg agcagctaga tcgcggtatt caccttgaat
    13801 cgggaacagg tattttggtt tgacgagatt aatcatcagc tgcaggtcac gcgcattggc
    13861 atgtccagaa acacgtaaat gctgcgtgat gagcttaaca gagccacctg ctttatagat
    13921 aaggttttca acacgagcaa ccattgcttc cttggcagcg cttggcgttg tgacaatgta
    13981 aaccagatct ccgtccttga tttgcacgtg gcgatgacgc cctattgcca ttttctgtag
    14041 gctattaatc ggctcaccca tacgtccagc ctccagaaca atcaattcgt gatcctcaaa
    14101 cttagacata tcctttggct tgattaatag cttttcatca gcaatcacta gctttttaag
    14161 acgaagtgct gttctgacaa tattttcagc gtcagtacct gtcagtacca ctcgcctgct
    14221 ataggctgct gcagaatcaa agacctgctg gatacgaaca agatttgaag cgacagctgc
    14281 aataataatc cgcccgtcgg catgagcaat caccttatcc atctcctcgc caacctcagc
    14341 ttcgctggca gtctgctcat tgcttgtggc attggccgag tcagctaata gggctaacac
    14401 cccttctttt ccaatgtctg ccaagcgagc taggtctgtc tgatagccct cacgcgaagc
    14461 ctggtcaaac ttgaaatcac ctgtatagac aatattcccc ttatcggttc caataaccac
    14521 gcctaaactt tcaggaatag aatgtgttgt cttaaagaag gaaaccaagc catctttaaa
    14581 ttcaatttct gtgtcactgt cgaccacatg gaaattctta aatctcttgg tgctattatt
    14641 ggccttgaca aacaattttg ctagctcgat ggtcaattct gaaccaaata ctggcactgg
    14701 aacctccgcc aacaggtaag gcaaagctcc gatagcatca gcatgcccat gacttaaaaa
    14761 gactccctga accttgtcct tgttttcaat tacataatca agacttggaa ttaccaaatc
    14821 tacacctagc tgttctgttt cagggtattt caagccagca tccaaaatga acatggaatc
    14881 gttaatctct actagataga agtttttccc gtactcacgt acgcctccta atgcaataat
    14941 gtttatatca gtcatgatac tccttttttt atattagtta ttacaaacgg tccttactgg
    15001 gtaagtcgaa ttactgtctt gcagctaagc tgcactcttt tacagtatat catattttag
    15061 ggcttattac ctcaaattgc cttgagactt tctcaatctt ttcaatagat tatcaaaaaa
    15121 gccaagggaa ggctttcatt ccaatggctt ttagagtatt tattttagtc aaaaagctgg
    15181 taataatcag caatggtcat ttgagatttt ctcttctgat caaggtcttg aatgatttta
    15241 ccatttttca tcacaatcag gcgattacca tagttaagag cgtcctccat gtgatgcgtt
    15301 atcattaagg ctgtcaagcg atccttagct acaaaatcat cagtcaaggc cattaaggct
    15361 tggctggtct tagggtctag cgctgcagta tgctcatcta atagtaaaag ctctggtctt
    15421 tttagggttg ccatgagtaa gctaagggcc tgtctttgac cgcctgataa gagaccagtc
    15481 ggagtctcca gatgattttc caagccattt ccaactcgct tgaccaagtc agcaaagtct
    15541 gccatataat ggctaatcct gcgtgatgac aagcctcgcc tttcccctct ttgccttgca
    15601 atcaaaaggt tttcagctac tgtcattcga ggtgctgttc ccattttagg atcctgaaaa
    15661 acacgtgata ggtagctagc tcttttttct gctggcaggt gcgtcacatc atgccctaaa
    15721 agcttaattt gacccttgct taacaatagc gtcccagcaa tcacattaaa aagggttgat
    15781 ttaccagcgc cattcccacc aagaatcgtt aaaaaatcat gctcataaat ggtcaaggaa
    15841 acatcatcta aaatagcctt agtctcatca aagccattat tgacttcgac agtagcgtga
    15901 attaattcaa taatttttct catcgtgata agctagcctc cttaataatt gcttttttta
    15961 gcacaggcac catcaggcaa agtgctaata taatggcact aaatagctta agataatttg
    16021 tattaaagcc aagagcaata actactgaga ttaaaaattg atacaggata gaaccaacca
    16081 caatggctat caagcgctca agcagggtta ggcctgtaga atataaaacc tcaccaacaa
    16141 taatactcgc aaggccaatt acaatcacac caatcccctt tgaaacatca gcatagccat
    16201 cttgctgact aaccaaggca ccagataagg ctatcaaggc attagagatc gctaagccca
    16261 taagctccat acgatcagta tgaatcccaa agctcttagc catatcccga ttatctcctg
    16321 tggcaatata agcctgacca atattggtgt aaagaaaata cattaacaaa aaaatcacca
    16381 atgtagctac aaccaaacca gctaccaaca cattggtgtc agctgcaaag ggaaggtagt
    16441 cctgaatgcg cttgatatca tgcaagccca aattggccct gcccataacc ataagcataa
    16501 tggaatggca ggaggtcatg actagtatgc cggcaagaag tgttggtatc tttccttttg
    16561 tgtataacag gcctgtggcg aagcctgcca aggcacccgc cagcatagca gccagagtag
    16621 ccaggatagg atttaaaccg agattgagca gagttactgc tacagcacct cctaaaggaa
    16681 aggacccttc tgttgtcata tctgggaaat tcaatattct aaaggtcagg taaatcccca
    16741 agccaagaat tccccataac aagccttgtg atacagatga aataatcata tgaactcctt
    16801 ttctattgct tacctgtaag gtcagaacgc ttcagcaggt cttttgagat cataagacct
    16861 aaatcccttg ctgcctttag atttaaaaat ggcttaccgt catcaactac ctcgacagga
    16921 acctctgata cctcttttcc agccataagc tgcagcacct gcctagctgt ctcaacccct
    16981 aattggtatt gactttgtga aatagaagca agactccctt gctcaaccat tgtatcaaca
    17041 cttgagtaga ccggaagctg tgctgcattt gaggcaacaa tcaccgctga aaaagcactg
    17101 gcaatagtat tatcctgtgg gataaaaaca gcatctacct tctcagtcat cacagacatg
    17161 gtcgtggtaa cctcatttgt tgaggggaca gcgtaagcta gaacctccaa gccttgcttt
    17221 tctgcaagag ctgtaaagtc cttgacctgt gatattgaat tgtcctcact gcttgcataa
    17281 aggacaccga cccttttgac ctgaggggtc atctccttga tcagatcaac cgtctgtcga
    17341 acaggaacct tatttgataa gccagtaaca tttgcctcag gcctgtctaa gtgcttgact
    17401 aatttagcac caactggatc agaaatagct gacatcacaa ccgggatagt cttggttgct
    17461 gctgctaatc cttgagctgc aggcgttgcg atgccaacaa caatatcgtt tgttttgacc
    17521 agctgcttgc tcatggtctg aatcttactt tgatctcctt ctgcattcat aagggtaatg
    17581 ctgacctttt gctctggctg atgatgcttc tttagctcgt ctttaatgcc ctgtgcaatc
    17641 tggtcaagcg cctcatgagt aaccagctgc aatataccaa ccttaaccac acgcttgctg
    17701 gctaactgtg gctgtttttt gccctctttt agcactagcg aagcagcaac cattaaaaag
    17761 agtgcaatga ctgttacgat aagaccttta tgtttcatgt tctacctctt aatttccatt
    17821 cttactccgt tgctaacatt tagagtactc acaaaaagaa aaaacgctta gtaatcagct
    17881 actaggcgct ttttttgaaa tccaatgtca gcgcatagat acctttttag aagtactcta
    17941 aaagtcgtat ctatgctaac ccataaacac aactttatct atgccagctt tgccaattta
    18001 tcatatgctg tgtttgcttc atcttggatt tcctttcttg tttttttaca ttataaccta
    18061 aaagctcaaa aatacaagag catttgaaca tatttttcca ttattttttg tggtataatg
    18121 aaagaattag aactcaggag ggagaaacca tgtcatttga cggctttttc ttacatcatt
    18181 taactcaaga gctcaaccat agtattgtta atgggcgcat tcaaaaagtc aatcaaccct
    18241 ttgataatga gttggttctg actatccgta accatcgcca aacttacaag ctcttgctct
    18301 cagctcatcc ggtttttgga cgcattcaac tgacccaaac agactttcaa aatcctcaat
    18361 ttcccaatac ctttaccatg atcatgcgca aataccttca aggagctatc attgaaggct
    18421 ttgagcagat tgataatgac cgcatcatcg aaatgaccgt ctctaacaaa aatgagattg
    18481 gcgatgccat aaagacgaca ttgatcatcg aaattatggg caagcacagc aatattattc
    18541 tggttgaccg tcatgaaaac aaaattatcg agtctatcaa gcacgtcggc ttttcccaaa
    18601 attcctaccg gactatttta ccaggatcag cctatatcga gcctccgaaa acaactgctg
    18661 tcaatccttt tacgatctca gatatcgctt tatttgaagt cctgcaaaca caggagttat
    18721 ctgctaaaaa tcttcaaaag catttccaag ggcttggccg agataccgca caagagctat
    18781 ccagtctcct gacaactgat aagctaaaac ggtttagaga cttttttcaa agacctagtc
    18841 agccaagtct aactcagacc tcctttgctc cagttgcctt ctcaaacaca ctgaagacct
    18901 tccagaatct atctcagctg ctagattatt attatcatga caaggctgag agagatcgta
    18961 tcaaccagca ggccagtgac ctgatccacc gcgttcaaaa cgaattggaa aaaaatcgca
    19021 gcaaactgat taagcaagag gctgagctgc tagccactga aaatgcggag gactttcgcc
    19081 aaaagggtga gctcttaaca acctatctga gcctggtgcc aaatgaccag gattcagttg
    19141 agcttgataa ctactatacc ggccaaaaaa taaccattgc acttgataag gcgttgactc
    19201 ccaatcaaaa tgcccaacgc tattttaaaa aatatcaaaa attaaaagaa gctgtcaagc
    19261 acctctcagg tctcatcgct gacacgcaac aaaccatcgc ttattttgaa agcgttgatt
    19321 acaatctatc tcaggcaacg attgatgaaa ttgaggacat tcgagaagag cttattcagg
    19381 ctggctttgt gaaaagccgt aagcataaca agcaccacaa acgtaaaaag ccagagcaat
    19441 acctggcttc agatggcaaa acaattatta tggtcggacg taacaatctg caaaatgagg
    19501 aattaacctt taaaatggcc aaaaaaggcg agctctggtt tcatgctaag gatattcccg
    19561 gcagccatgt gatcattaag gacaatctaa gcccaagcga cgaggtcaaa actgatgctg
    19621 ctgaattggc ggcctattat tctaaagcaa gactttccaa tctcgttcag gtggacatga
    19681 ttgaagccaa aaagctgcac aagccaagtg gtgcaaagcc tggctttgtc acctatacag
    19741 gacaaaagac actaagagtg acacctatag aaagcaagat tcaagccatg aagtgctccc
    19801 cttcagcctc ttcctcatag gactacagca ataaagataa aaaaagctac agcctcacac
    19861 ttggagatag gtccagtctt aaagctgcgg cttttttatc attacttgtt aatcatctct
    19921 caaatcatct aagaagcctt gcatatgaat atcatctgga acctgctgca aatacctttt
    19981 tgcctgctta actgcttgat cagtatagcc gaattccctt aataaataag cataatcctg
    20041 taaaaagtca ggattttctt ttaggtctcc ttcgatatct ttatagatag tgagggcttt
    20101 ttcttgctgc tccagagcct gataggcctt ggcaagattc catttagtta gcacatgatc
    20161 aatctcctca tgctcaagag caatgacctc ctcaaaacgc tccatatcca agtacaggct
    20221 agataagcgc atgatgacct cttcgtcatc aacagctact tccttggccc tgagcaaata
    20281 ccgctctgag ccagctggat catgcaattc aaaggcaagc tgtgaagcaa gcaacagcag
    20341 ctgggggtca aaggcatttt tacgcagacc ctgctgaact aggcgtaagg cctcttctgt
    20401 ccgatgctcc tcacgcaagc tcatggcata ggggtactcg tagcctaaaa agtctgcatt
    20461 catcgtttct aattgcttga aatagagatt ggccttttgg taagcagcct gatcatataa
    20521 aatcgtcgcc agctcaaaca ctgtctcatc gtcatactca atggcaagag ccttttcaag
    20581 aaactctaca gcagcttcaa atttccctaa ataagcatag gcacgcccta tgcgctggta
    20641 ggttgagata cctgtcagct caagaatgtg acgattatca agcctagcat attgctcaat
    20701 agcctcgcta aagtgctcca gagacatctc gatttcggct aagccaaaga tcactatcgg
    20761 ctcctgactc aattcagctg cttgaagtag cttctcacgc gccacatcag ttagcccctc
    20821 caaatcataa agatcagcca tgacgagcag agcagacaaa taatcagcac tatcctctgg
    20881 aatcctatca aggtacataa aggcctcttc aatgacatta tcctcagctg caatctgagc
    20941 aagattaata ttgacctccg gataagcctc acagacctgc aaataaatcg tcttagcatg
    21001 cagtaaaaaa ccaatactct ctaggtattc tgccaaagcc aacaaggtct cagcatcgtc
    21061 ctcctgcaag gctctttgaa aatagctttc tgcctgctct aaatcctgtt gctctagtga
    21121 ggcaatcatt ttttcactat ttaacatctt cagcgaccct ctcagcttct gtaggctctt
    21181 cctcatacag gcctgtaata tccttgtacc aatcaaatag ctccttcaca acaaccttaa
    21241 cagaagcata aactggaatg acaagaaaga caccccagac cccaaacatt gaccctgctg
    21301 tcaataataa aaacataatg gtaatcgggt gaatgctcag cttatttcca agcactagcg
    21361 gcgcgacaaa acgtccttca atcgtttgtt caataacaaa aataatcaac accttgatca
    21421 gcatcaaggg tccttgcacc attcccataa tcactacagg aatcatggct aaaaagctcc
    21481 ccagataagg aatcatatta agaaagcctg caataatacc aaaggtaata gaatagttca
    21541 aaccaacaag gctaaacatc actgaaaaca tgagaccaac cacaatcgca acggtcacct
    21601 gtccctgcac atagccagat aattgcttgt tgatttctcc taagacacgt gccataggct
    21661 ggcgcagctt aatcggaagc acattgacca aaccattttt catatggcca ctgtcacgca
    21721 gaaaataaaa gagaataaaa ggtgacatga tgattgcaac agtaatacgg gcaatagctc
    21781 cagcaaaatt tcctgcccaa tcaatagcat ttttagagaa gctttgcgca taatctagag
    21841 ccttttggct catactagtc agcatatcct gcaggttgga cctgtagcta accagccatt
    21901 cgttttcaag tagcttatta gcctctagat tgaccttggc aacatatttg ggaaggtctt
    21961 cgacaaagct ccttagctgg tcttgaatca tagggataaa gccagaaata gcccagaaaa
    22021 ataggagaat tactaagcca aagacaataa aaatagaggc tgtgcgattt ggacctagct
    22081 tctcaaccat atcaactaat ggcttggtca aataatacag gatagttgag ataaccagcg
    22141 gcagcatgat aatggccaaa aatgacaaga tcggtgtaaa gaggaaggat atttttgtaa
    22201 agacaaaaat agtcagaaaa accagcagcg tgattaacaa aaccatcacc gcctgattat
    22261 ttaaaaacca tttgtaaaat agactatcat gatgattagg cttagaatgc aatgacatta
    22321 atggtatcgt cctttcttaa ttgtggcatc attctgatga gagcttttag gttagttgac
    22381 ttaataaaag gtgactgttt tttccactag cttgttgtgg tcatcatacc taaatttagc
    22441 agaaaaaaac ggccggtctt ccagtatcca cttgaaaatg tcgtaatctc cctcccaggt
    22501 tggcttttcc agcacctgat catagggaac ccattctagg gtcccttctc tggactcctc
    22561 atcagcaatt aagtcacctt caaagtctgt caccttaaac acgtaagtat accaatcatg
    22621 ccctggtgta aaatcaggaa aggtaatcac tcccttaaag tccattgctt ttaccagcag
    22681 gtgagtttcc tctaaaattt cacgtctggc acagtcatca ggagattcgc ctggctctaa
    22741 tttgccacca actgaaatcc acttaccttg gtgaacatca ttttccttct tgttgcgatg
    22801 cagcagcaat aaagcctcac cgttatcaat ataacaaatc gttgctaact tagtcattca
    22861 tacccttcct ttgtttagtt gttactatta taccaatctc tgagaaatat gccatcattt
    22921 tatcatttaa gcacatcaaa caagaaaacc acaatcacta caactcttag ccctgtacta
    22981 gcaaaaaagc cttgataagg caacgtctgc tgactcatca agacttatca ctatttaacg
    23041 aatcacttcc tgtgtcttag cgtaattggc ttcaactgct tctttttcgg aacgccacca
    23101 atcctgatga tcagtatacc attggatcgt ttgctcaagt ccttctgaaa aatcagtaaa
    23161 ctgtggctcc cagccaagct cctgacgaag ctttgtcgaa tcaatagcat agcgtaaatc
    23221 gtggcctgca cgatccgtta catggtcata agcgtcctta ggctgcccca ttttatccag
    23281 gattaattcc agcacttcct tattattttt ttcgccgtca gctccaataa ggtaggtctc
    23341 accaatacgt cccttggtca aaatggccca aacaccagtt gagtggtcat tggtgtgaat
    23401 ccagtcacga acattctttc cttcaccata caattttggc ttgataccag acaagatatt
    23461 agtgatctga cgagggataa atttctcgat atgctggtag ggaccataat tatttgaaca
    23521 gtttgaaatg gttgccttca cgccaaagga gcgaacccag gccttaacaa tcaaatcaga
    23581 ggctgccttg gttgatgaat aaggtgacga cggattatag ttagtatcag cggtgaattt
    23641 ttcacctggc ccctcaccat gacctggcaa atcctcacgc agtggcagat ccccataaac
    23701 ctcatcagtg gacacatgat ggaagcgaat atcatattta cgagccgcct ctaagagtgt
    23761 ataagtccca acgaagttcg tgtaaataaa tggacttggg tcattgagtg aattatcatt
    23821 gtggctttca gcagcatagt ggacaatagc atctgcctta gcggccagct tatctaccaa
    23881 ttcagcatca gcaatgtcac caacaaccaa ctccacgcga tcacccaaaa tctcctcaag
    23941 gttggcacga ttgccagcgt aggtgagctt atccaaaaca gttacgtgaa cctctgggtg
    24001 atggttgtaa acataatgta cgaagtttga accgataaag ccagcgccac cggtaacaat
    24061 aatgttttta tattcagaca tgttttttct tttcctttgt tttcagctat cagcactcaa
    24121 aatgcagctt aatccgacag gcaagctcag ttaccagtga aaacagcgac taagctgcct
    24181 cacctcattg ctcctaccat ccataaggtc cttcctatca gaaggataca gagacactcc
    24241 catcaaaagc catagcttat ttcaaatgct aattatgata aatcttcttg tctcaaaggc
    24301 ttaacggcct ctaggaaggg atggctttta tctgcttctg aaacctctgc ttgttcaaga
    24361 ctttcccacg caatcccaag gcttgggtca gcataattaa caaaggcata tttttgcttg
    24421 agctcaagcg cccaataatc attgaccaga taggtataag ccaccttatc agtcagtact
    24481 tgaaagccat tagcaacacc tcgagggaca aaaatcccct ttgaagcgtc aatgactgtt
    24541 tgataggtat gcccaaagct atcaccctca cgaagatcaa cccaagctcc aagaacctta
    24601 ccctcatcag caacagagat gtacttgtcc caaggctctg catgcaggcc tcgaagcaca
    24661 tgcttgcgcg aaaatgaaat attgttttgc agcttacctg cggcaaaaaa ctgctcagga
    24721 aagcctagag gaatcatttt ttccttttga aaattttcct taaaccagcc acgattgtcc
    24781 cctcgaacag ggatatcaaa ctccaaaagt ccaggaatgg cttcaatttc ccgacaggct
    24841 aaggctttat caaaaaattg ttctgtcatc aagcttctcc aatcaaccgc agcaggtact
    24901 gcccgtattc gtttttctta agcgactgcg ctagctggta gacatcttct ttagtgatat
    24961 aacccatgcg ataggcaatc tcctctaggt tggccacctg agcgttttgc aagcgttgaa
    25021 ctgtctcgat gtattgggca gcctccagca ggctttcatg agtgccagta tctagccagg
    25081 caaagccacg tcccatcaac tcaaccgata ggtcgccacg ctctaaatag gctttattaa
    25141 catcagtaat ctcaagctct cctctggcac ttggtttaat gcttttagca atctcgacta
    25201 catcattgtc gtaaaaataa aggcctgtta cagcaaaatg tgacttagga actgccggct
    25261 tttcttcgat agaaatggca ttcatctcat cgtcaaactc cacaacccca aaacgctccg
    25321 gatccttgac ctgataacca aaaacagtgg ctcctttttc cttagctgct gccttttgga
    25381 gcattttcgt aaggccgttt ccatgataga tgttgtcacc taaaatcaag gcaactcgat
    25441 catcaccaat aaactcctca ccaatgataa aggcctgtgc taagccgtca ggacttggtt
    25501 gctccttgta ggacaagctt atcccaaact ctgagccatc gcctaatagc tcttcaaatc
    25561 ttggaagatc ttggggagtt gaaataatca aaatgtctcg aatccctgcc agcatcagtg
    25621 ttgataaggg ataataaatc attggcttat cataaattgg catcaattgc tttgaagctg
    25681 cacgagtaag agggtacaag cgtgttcctg atcctcctgc cagaataata cctttcatcg
    25741 tagctctcct cattttataa tacgtcacta ttttatcatt ttttaaaaac agtgtcactt
    25801 tttatcatta atccgacgaa tataatgatg aatcgggtat tgactagtat ctaagctagc
    25861 tttttgcccc aaaagcaggg caatcagctg ctgagcaatc aaaggaccta gggtcaagcc
    25921 agatgagcct agaccgcttg cggcgtaaac acctggtagc tgaggtacct gcccaaaaaa
    25981 tggagaaaaa tctctggtat aggctcgaat gcctacgcgg taagaaacat cagaggcaga
    26041 actcagctta gggtaatagg tcaaggcctc ctgctccaag gcctctaaaa cagctacatc
    26101 aggctcaagg tcatagccct tatcattttc atgactcgct cctacagaca acctatcatg
    26161 ctcaaaggga ataatatcca gctccccctc tggcatgacc actgcgtagt tatctgtagt
    26221 cacattcgca atgtgataat caatgagctg tcctttttgc ggtcgaatat ccacctgata
    26281 gccaagtggc tcaagcaatt ctggcagcca agcaccagcg gctagaatca gccgatcaaa
    26341 gaccatacca tcaacgagat agccttgctt ttctatgctt atgccaacac gctttttaac
    26401 cacctgatag ccactagctt caagcaaaca ctgacatagg tctgccccat caacacgtgc
    26461 agccccagaa gcccatacca gctgctcaaa accctgtaaa tcaggaaaat caaccctaat
    26521 gtccgaacga caccttatcg ccaaatctcc aatcaaaggc gactcttgct tgcgtctaat
    26581 ggccagctgg tagagctcct ctagcttgtc ctcattcttt tttaataaat aaacaccagt
    26641 ctgcttataa aaatgtgtag aaagcccctc tttttgcagc tccttgatta agtcctgata
    26701 acaatctgct cctaaccgag ccagctggta ccaagcctta ttccttcttt ttgaaaacca
    26761 agggcagata atgccagcgg ctgccttagt tgcttgacca ttaccatcat caaaaatagt
    26821 aacctgctga tacccttgtt tttttaaata ataagcggcg cttgaaccta caattccagc
    26881 tccaatgatt gctatcgttg tcattgccgt ttccattcta tcatactgct taccaagcat
    26941 aggccatact cagtcatgct atagatgact aaagggattt gttgacgcct tgctagccat
    27001 aatggttact tgccagcctt cctctttttt ccaagcctgc atcttggcaa gtagtttatc
    27061 aataaataag gactcgatgt gatgccctgg atcaattgcc agcaggcctt ctgtcagcat
    27121 ttcctgtgct gtgtgataat aaatgtcacc agtaatataa acttgagctc ccttagcaag
    27181 cgctgcctga taaaatttat caccactgcc cccacaaata gccactcgcg aaatcaaagg
    27241 gttttgacca gtatatcgaa ccagccgaac cacatcaagc ccaaaggctt ctttaactgt
    27301 aagtcctaac tcctccaagc tttgctctgc tacatttccg acacgtccaa taccataccc
    27361 atcttgcgtc tcaaccaata cctctgtctg ctcaatgccc aacagctcac aaaaccaatc
    27421 gttgagcccg tcagagacaa tatctatatt ggtatgactg acatagacag aaatatcgtg
    27481 cttcaccagc tcaaggacaa tatctcgctg tggcgaggag accaagtcct tcaagccctt
    27541 aaaaatagga gcgtgcttgg tgataatcag gtctaccttg gccgcaatag cttcggcaac
    27601 ggtattttct ctcacatcaa gggtgatcat tacccttttg acctccttat ccagagagcc
    27661 aatttggagg ccacacacat ctcctgacat ggatagctca agcggacaat agctttcata
    27721 tttttcgatg attgttctag ctttcatgac tgatgacctc ctcaatcgct tttatttttt
    27781 gagaaatgct agcgcgttca acaggcttcg ttgctggcac acaagacagg gcatagacaa
    27841 gcttatctcg ctctttttgc catttagcca caaagactga tgacctttcc tgagacaaga
    27901 aaggaccaaa gcgctgctcc tgatctgtta gactttgttg accaggctct gcaacaatga
    27961 tttcataata tttgccattt tctgtcatga tggtttcagc actaatacaa aaagcattgg
    28021 cagatagcca agcacgcagc tcatcctctc gattattggg ctgtaaaatc aagcgctcaa
    28081 tcccttgcag cttttcctta ccagccgcta aaatgtcagc tattaaacgc cctcccatgc
    28141 cacagatggt tatgcagtct acagcatctc tcgcctcaaa ggcagctaag ccattagcca
    28201 gacgcacctc aatatgctct gtcaaaccat attgtgacac attttttagg gctgatacaa
    28261 aaggtccctt gaccacctca cctgcaatcg cctcttgaat atgctcggtt tcaaccaaaa
    28321 aaataggaag ataagcatga tcacttccca cgtctaaaag cttagcacca tcagggacat
    28381 aggatgccac atggcgtaag cgctttgata aatgactttc cattttctta atccttctaa
    28441 caactaatcg tatcactatt atagcaaaat acagaccaat taaaaagaaa gccacatcag
    28501 accttctttt taccataggt agtcttgtaa tagctgcaat agctctgtac tgggcaggta
    28561 tcacacttag gatgcttagc caagcagtga tagcgtccaa aaaagatcaa acggtggtgg
    28621 gtgatgatcc aatccttctt aggaagcttg gccatcaaat cagcttcaat ttcagtaaca
    28681 tcggcatctg gggcagaaat gttcaagcgc ttggcaatcc ttgacacatg cgtgtcaact
    28741 gcgattgcag ggacaccata aatctctgcc aagaccacat tagcagtctt acggcctact
    28801 cctggtaagg attcgagctc cttatgggtt tttggtacct gaccatcaaa ctgtgtcagt
    28861 agctgctgag ctgtcttgat gatatttttt gccttatttt tatacaagcc aattgtcctt
    28921 aggtgatcct caacatctga cacatttgcc tgagccaaat ctgaaagctc tgggtagctt
    28981 tgccacagct taggggtaac cttgttgact gccttatcag ttgtctgcgc tgataggata
    29041 accgtaataa gaagctgaaa gggcttttct tggtcccaat tcagctcgcc cttagcctct
    29101 ggaaacatct caccaatgat tgatagaacc ttttttaatc gttctcttcc tatcctcatt
    29161 agttactcca aaggttcatc gccgcaagaa aatcatctga aaccgtcact tcagacgccg
    29221 tcatatcctc tctggcacgc tttttttcct caagctgcct gaggcttgta attccctcct
    29281 tgcgccaatt tcttagaata gcctgaatat atttccaatt ggtttttcca ttaaagacag
    29341 cctctctcag cgcctcacgc actaaatcca gatctgtttg gtcatcatga atggtttttt
    29401 ccaaatcctc tagctccatc ggactcaaaa aacgacccag ctcacgctca aactcatcaa
    29461 caagaagttt caattggttg gtgttttgct gttcatgctc acccttttca tcacgcgcca
    29521 atagctggtc taaagtgact aatacaggac tagcatcaaa aatgatctca atctctccag
    29581 ccagctctat ggttttcata tctaataacc cctgactggt caaggaagaa atagccttat
    29641 tcacctctgc tacagactta cccaaggcat tagcaatctg actaggtgcc aattcgtcaa
    29701 gcctagtcgt attttggaga tagaaaaact gccaaaccaa aaaatcgtct gagctcttaa
    29761 aaatatcctt gtaatgaaac agtaaggcag ttggaaggac caaattgcca gactgataat
    29821 gctctaaaaa actcataatt cccctgccaa acgtaatagc ccaacctagc ttttaatcag
    29881 tactgccatt agcaagcact gattaaccag gaaaatgcat caatacctta caatcgtaat
    29941 caccaatagc ctgacgacca ttcaagccgt ccagctcaat gagaaaagcg cagccagcaa
    30001 caatgccgcc cagcttttca accagatcaa tagtagcctt tactgtacca cctgttgcta
    30061 ataagtcgtc cacaataagg acacgttggc ccggcttaat agcatcagca tgcatggtca
    30121 aggtgtctag accatactcc ttttcatagc tagcagaaat cacctctctt ggcaatttac
    30181 ccggcttacg aacaggagca aagccaattc ctagctcaac tgcgaccgga cagccaataa
    30241 taaagccacg agcctccggt ccaacaatca tgtcaatgtc cttatcgcag gcatattgca
    30301 caatctcacg aatagcatag ctgtaggcct tgccactagc cattagcggc gaaatatcac
    30361 gaaaggtaat cccctccttt gggtaattct caattgaagc aatatattgt gttaaatcca
    30421 tcgtaaaata gtctttctaa tgtcttttaa attaaaatct ttcctattat agcatgaaag
    30481 tctaaaaagg taaatgattc ctaatcatcc agatcaatcc ctttttcctt taaattagtc
    30541 aggcattcct gtaaataggc ctcttgatgc tcaggataaa tcggtgaggt cagtgccacc
    30601 tcctctaagt cctcataggc ggcaaggctt tttcctcggt aatttttatc ctgccagctc
    30661 acatctggct ggtagccccg cgcctgcatt tcctgcataa tcaacaggtg atactggtaa
    30721 agcttataaa gagaatgggc aaacacatag tcaaccgtcg catgtggtct cccccagcct
    30781 gctcctcgca aggccgcaca ttcacgatgc tgccccaaca attgctgcct tggtaggcgt
    30841 gtgattaaat cctgatgcca aagacgcata agctctccta tttctcttca ctagtcatta
    30901 aatactgata aatctcctgc ggactgccca aggccataag ctcttgaaac tttaccagct
    30961 cttttagctg ttggtaaatg acactgtcag cgatgctacg ttttggggca tcagtcttta
    31021 ccctcatcag cccatcttcg attactacaa agcctaactc ctcaaaaatt tgtatcattt
    31081 tgaccaagag gattttttca atcttgaggt aatcacttag caaggtcagc ttatggcgaa
    31141 gatcaaattc tgggtattga tagatggtct tataaagctt ggcaaattgc tctctactgc
    31201 catagcctgt taggtaataa gggcgcttaa tatgattttt aaagtaaatc gcttcaaatt
    31261 cccgatgtct aaaaaggcct ttcaaggcat caatatcgtc aggaacctca tctatgacaa
    31321 caaccttggc ctgctggtcc tcaacagctg taggaatatg ctcaggtgcc ctagcagtcc
    31381 ttgctcgaat atcaaacagc tgcaccccag tcactctagc gtcaaccagc attaattgca
    31441 ggctagtatg acctcgccag tgattgatcg caagactaac cgctaattcc aagccctgtg
    31501 attgctggta ctcctgtatc agatgtccct gaccaaaggc caagacatca gcctcaacgg
    31561 ctcctttgct gaccttgaac ttcaagtgac tttgttgctg accaatggtc cttgcctgct
    31621 taatcgtaaa atcttttaag taaaaaacag gctttttatt atccatgcca aagggtgcta
    31681 gaagtagcag cttgttcaga ctatctatac tcaatgcttc taaatccaat tcaccattga
    31741 tcaatagagt gtttttttcc tgaccatcgt gtcccttggc tgccacgtat tggcaaagta
    31801 gctctgatag ctcctctagg cgatcagatg gcagagtcat gcctgctgcc ccctcatgac
    31861 caccaaaggc tgtaaataag ctcctattgc tattaagtgc ttcaaagata ttaatgctct
    31921 ctaagcttct ggctgagccc ttggctagcc cctcatcaat ggtcaaaaca agaacagtct
    31981 gcccaatctc ctccatgatc cgaccagcta caatccctaa gacccctggg tgccagccag
    32041 acttagctaa aacctgcaca ggcttgtcta gatcaagcat agccattgct tgagcaaaaa
    32101 tctcctgtac caagaccttt ctttcctcat ttttactact aatcatcaag gcaagctcat
    32161 gaagctcttc gtcatcaaag cctgtcagta gatcaatagc tggatttgga tcgtcaagac
    32221 gccctagagc attgagctgc ggagcaagct taaagctaat aacatcttca tcaaaatgcg
    32281 ctaagtcaac ctctgaaagc ttcatcagct cctgcaagcc tagtctttct gtctctttta
    32341 gaacagccag cccgtttttg acaaggatac ggttttcacc tcgtaggctg accatatcag
    32401 caattgtccc aatagcaacc agatctaaaa agtctactgg aattgtctct aacagagctg
    32461 aagccaactt gaaggcgacg ccacagccag ctagtttttg aaagggataa gcagcagctg
    32521 ggtgctcagg gtgaataata gcaaaggcat caggtagctc tgctggcagg ctgtggtggt
    32581 ctgttacaat aacatctacc ccctgtgctt gcgcaaaggc aaccgcttca tggcctgaaa
    32641 caccattgtc aacggtaata atcagcgaaa cctgctcttg ctcgatgaaa tacttgtaaa
    32701 cactttgatt gggaccatag ccatctgtaa agcgattagg caaataaaca agaggctctg
    32761 ctcccatcat ttccagcgtt tccttgacaa tagacgccgc tgtcatgcca tctgcatcat
    32821 aatctccgta gaccaaaatc ctctcaagcc cctcaatggc ctgacgaatg cgatgaacag
    32881 ctttttccat atcatttagc aaataagggt catggagctg tgataggtca gctgtcaaaa
    32941 agctggtaag ctcctcttcg gtatgaacac ctcggtcata gatgagcttt gcagctgtct
    33001 gactaagtcc ctttgcctga gctagcttaa agaagccagc atctggctcc ttatcagcta
    33061 tggtccactg atatttggac gtaatcattt ataattaaat acctttcttg caagataatc
    33121 agatatagtt ggaaacaagg tataacactt atgagcaagg gctaggctaa taggcagatt
    33181 aatctctcgt ttcttttttc ctattgcagc aatgattttt ttcgccacag tatccgcctg
    33241 cagcgtaaag cctgcaacac tggctaaata ctgcccgctt gggtcagcct gctcaaaaaa
    33301 ggaggttgca atcgggcctg gattaacagt tgtcacataa acctgccttt ctgccagctc
    33361 caagcgaagg gcattagaaa agccaatgac tgcaaacttt gtcgcagaat agatacttga
    33421 cttggcagaa gctattaagc ctgccattga gacaatattc ataatatgtc cagagccctg
    33481 ctctgccatt ttgtggccaa gcaagcgtgc aaaatgaatg ctggctaagc tattcacacg
    33541 aaacatggcc tcaatctctt ctgcagagaa atcatcaaag gccttaaaag caccaaagcc
    33601 tgcattgtta atcaaaacat caatcctgcc atggcgctgg taaagctcat caacaagagc
    33661 ctcaatagca gcagggtctt gaatagcaat ctcgtagcat tccttattac cgcgagcctg
    33721 atatagactg tctaacctgt ctttgctgcg ccctaacaaa atcaggtaat cttctcttgg
    33781 aagctgtctg atgatagcct gtgcgagccc gccagaagca cctgttatca gaataattct
    33841 ctgtgccatt aaatgatcac ttcctctaaa tcgcgaacaa ccttcacatt ttcaaaaata
    33901 gttgccgcat ccttttccat ttgacgacag tcacgtccta aaaagcgtgc tgaaacatga
    33961 ttcagtaaaa gacgcttagc acctgcatca cgcgcgattt gagcagcctg catgtttgtc
    34021 gaatgcccat gattacgggc cattctttca tcacccttcc cgtaggtgga ctcatgcacc
    34081 agcacatcag catcttttgc caatctaaca ctagcagatg tcttgcgtgt atcgccaata
    34141 atggtgatga tctttccttt tcgaggctct gaaataaagt ccttggcaaa aattttggtg
    34201 ccatcctcta gctcaatatc ctgcccattt ttaaccttgc caaaaagtgg accaaagggc
    34261 actcctactg ctctaagagc ttctgcatca agtgttcctt ctaaatcctt ttgaaccaca
    34321 cgatacccca tacaaaagat ggtatgtgcc aagcgctcag cataaacaat aaatttatct
    34381 gtttctaaaa tcttgcccat agaggtgtca tcaaactcat gataatgaat ctgataaggc
    34441 aatttagagc ctgatatcct gatgctgttt gttacatagg attttatccc aacaggtcca
    34501 taaatctcaa ggtccgtctg ctcctcacta gcttgaaaag cccgactaga taaaaagcca
    34561 ggcaagccaa aaatatgatc accatgcaga tgcgtgataa aaatcttctt gatttttcgt
    34621 ggcttgattg ttgtttctaa aatttgccgc tgggttccct cgccacaatc aaacatccac
    34681 acctcattga tttcatctaa tagctttagc actaagcttg aaacgttgcg atgcttggct
    34741 ggctgcccag ctccagtacc taaaaattgt aattccatac agtctattct ttctaatgca
    34801 caaggtaaat catgaattct ctttgtgcaa actgataata tttctttcct ttgaatgctt
    34861 ggctaagagc caacaattca tcactattaa agccctttag cagggtcatt tcgtttgaga
    34921 aacgatagat cgtggttaac aaagcatgct caggtgttat gtcctctggc tctccttgct
    34981 caaattggca gctcttcatc ttgattctac catcttccac ataaaccacg tattgtggaa
    35041 aaatctgagc cagctccagc agcagcgatt cctcaggctg cccctgctct ttttcagcaa
    35101 aaacaatcgc ctcctgtgct tcattttcaa agacaaagcc ataggattgc cccaacaaat
    35161 ttaagcggac aaagggcttc acctcatcaa atgacggctc tgaggtaaac agcttcaagg
    35221 cccttgatag ctcaaaataa taatctgtcg ctgcttttgg tgattgcttc tgatacattt
    35281 ctgcaaaata agcattaatc acacttgggg gtggcgtgat ggtagctaat ttttgctggt
    35341 ctgtcaagcc ctttaagcaa ttttgcaaat aaaccgtatc taaactcgta aagcctccat
    35401 aagtctttgc caattgaata taatcagtca taaaattctt ctaatctcca tttatttttg
    35461 ggagcaatgt agccagaaat ctcttcaatc tccttatcaa agctataagg ctccaataac
    35521 gccaacctgt tgaggtcata gcatttgtag gcttgatcct gacagagctt gatcgaaaat
    35581 ggctcaaaca tgtcccgaat ctgatcaata agcaactgtc ttaagaggct acgactgttt
    35641 ttatcacgtg ctgacagcct gacatttgga aaaacagttg cagtcaagct agctgtctta
    35701 tccatcttgt tataaatagc cagccttgga atatccagca tatctaaatc tttcaagatg
    35761 tctagaacaa ccctctcatg ctccaaatga ttagggtcac tggcatcaat cacatgcaag
    35821 agcaaatcaa catgccgact ttcctctaat gtcgacttaa aagcagccac gagctccgtt
    35881 ggtaaatctt ggataaagcc tacagtatct gtcagagttg cctgaaactg attttgcaga
    35941 taaatttgct tggtggtggc atcaagtgtt gcaaataatt catcagcctc atattgcttg
    36001 tcaccagtca aaatagtcat aatagtagac ttacctgcat tggtatagcc gatcaatcca
    36061 atattaaaga catcagaggt catgcggcga tcacgaatcg tttgacggtt tttttcgaca
    36121 gcagctagct gccgctcaat atctgcaatc tgatgacgaa tggagcgccg gttcagctcc
    36181 agctggctct cacccggccc acgactccca atgcccccgg cctgacgact aagcataaca
    36241 ccctgtccga ccagtcttgg cagcatgtat ttgagctgcg ctaaatgcac ctgcaatttt
    36301 ccttcatggc ttctagcccg catcgcaaaa atatcaagaa tcagctgcat gcgatcaatg
    36361 accttaatac ctaaggcgtc ctccaaattg gcattttgcc gagccgttaa acgattgtta
    36421 acaatcactg tatcaatctc attggcagca accatttctt tgatttcagc cagcttacca
    36481 gagccaacaa aggtcttgct atcatagcgc tccctctttt gcagatagca atcaacgacc
    36541 tctgcacctg cggtcttggc tagactagcc agctctgtca ttgatagctc agcatggtca
    36601 gctgcttgta ggaccacgct tagtaaaata actctttcct gccttgcctt tgtctctatc
    36661 atgaacgcga ctaatcctcc aaattccgta gtgtttatta tagcatagtt ttagctattt
    36721 tcagctagtt tgccatcgat agcttcctaa ggctccttca aaaagcgctc caccctatca
    36781 tatattgcct gcggatagga cgactcgcta atcgagtcaa agcgcactgc catacggtta
    36841 cgaaaccaag tcagctgtcg tttagcaaag cggcgtgttt gctgctttag tgtggctgtt
    36901 gcttcttcta aactagcctg accctgaaag taagggaaga gctccttata accgatccct
    36961 cgactagcct gaacagctgg atactgctca aaaagccacc ttgcctcctc caataggcca
    37021 gaagccatca tcagatccac ccgcttatta atccgctcat aaataacctc tcgctcatca
    37081 gtcaagccaa tgatcaaggg gttatagggg gcctcttgat tttctaaatc cctagcaaat
    37141 tgatttagct caagtgagcg aatggcacgc ctgcggttaa cctgatcaag gtgaatgccc
    37201 ttactagcta atagctgata aagctctgta tctgtcagtg tctctagctg ctgccgataa
    37261 gcaagtagct ccttttgatc aagatctcct cctagatgat agccctctaa caggctttgc
    37321 aaatacaggc cggtaccacc gacaataatc ggcagtttac cgcggctaac aatatcttca
    37381 atagctcgct tagcgtcctg cacaaaatca aaggctgagt aagactctgt cacctcacga
    37441 atgtcaatca aatgatgaac cgcaagagcc tgctccctgg cactagcctt agctgtccca
    37501 atatcaaggt gacgataaac ctgctgacta tctccagata taatttcacc attaaaggca
    37561 ccagccaagg caatccctag agctgtcttg ccaacagcag tcgggcctac aatcacaatt
    37621 atcttttctt ttgtcattta ttgtctttct acttaaaaag cagctgaaaa agtcttttac
    37681 ttgaattttc taatcttttt cgctaccata tattataaca taagattgag agacagttat
    37741 ggtcctctta atagaaatgg agaatgatta tggctaaaaa acatggattc gcaaagggtc
    37801 ttgctacagg tgttcttgct actgctgcta ccgttgcagg tgcagtattt gctgttaaaa
    37861 agactattat tgaccctgag gaagaaaaag cagcatttgt agaggaaaat cgtaaaaaag
    37921 cagcacgtcg tcgtgttgct cgctaatcac taatagatga aagattcgac aggctttatc
    37981 aatagcctgt cgaatttttt atgctgtgag accaagcttt ttgcttagac acataaaaga
    38041 aacagctcgt cagcgccgca tactgcctac ttcattgacc aacaaacagg gcaaactaag
    38101 gctaattttc actgatatga catgtttcga ctataaagcg gttttgtgat tgattgatca
    38161 caatatcaaa ttgctggtga taagggtgca gataacgagc atattgagcg cgcctattga
    38221 catgatgaac tccggattgc gacctctaat gctagtatct ctaccaagcc gcctttggag
    38281 ctctgtgtca ccatctgtat aaaagtaaag cgataagtca aacaactctg gctctaaaaa
    38341 ggttgtcgac atgccttcag caataaggat gggcacattc cccttcacca aaaaagaggg
    38401 agaccaaggg gtatcaatac tcaaaaaatc cagtccttgc ttaaacatca tgatgtcacg
    38461 cctcagactg gccaattcgt gcctagcagg gtgacaggct gttatactac caagtacctc
    38521 ctctccctga tcagggtagc taatcaaaac agcctgacta aaatcattag cgatgatata
    38581 ggcatctgtt tctaacaatt ggctttgtcc atcaggcaaa agctgctgta agcgcttagc
    38641 aaaggttgat ttaccagatg caccatgacc actaattcta ataagcattt tctcacgatt
    38701 ggctgctgca gttacaatag cttgaagtag cttctccatt atctctcctc atcaaataac
    38761 attctaataa taggacatca ttctacatcg aaaaacaagc cggtctcccg aaacagcctg
    38821 actgacagta aaaaaagatt gaagggcaat ccaataagga aagcttctcc aatctgatta
    38881 atagtctata atggcttaat atgagtgcca aatgtcttgg ttatattgtt caatcgtacg
    38941 gtccgatgaa aagaagccag ccttagcaat attatgcaca acctttgtca gccataggtc
    39001 ctgattgtca taatcagcca gcatttgttc tttgactgca atgtattcct caaggtcaat
    39061 caaggtcata aaccagtcct tagagattaa ctccttatag agacggtcaa gacgttcctc
    39121 attaccaagc tctaataatt ctggactgat aataaagtta actgcttcct tgatagctgg
    39181 gtgggcatca taatagtctt tagacacata accacctgtg gcataaagat caataatggt
    39241 atctgaatcc ttaccaaagg tgtagatatt atccatacca gcaagctcag cgatttccac
    39301 attagccccg tccatagtac caagcgtcaa ggcaccattg agcatgaatt tcatattacc
    39361 agtacctgaa gcttcctttg aagctagaga aatttgctct gaaatatcag ttgcaggaat
    39421 caaatgctct gctactgtca cattgtaatt ttcaacaagg tgaacattaa ggtatggact
    39481 tacctccgga tcgttattga taagctctga caagcaaaga atcaaatgaa taatatcctg
    39541 tgcaatgata taagccggtg cagccttacc accaaagata actgttattt tacgcttcgg
    39601 caggttgcct tttttgatct ctaagtattt atgaatcaca taaagggcat tcatctgctg
    39661 gcgcttatat tcgtggaagc gtttaatttg ggtatcaatg attgaatgct catcaagctc
    39721 aattccctta ttatccttga ggtagcgctt taaggctact ttattatggt gcttaatttc
    39781 agccaatctt gcatgaacag cttgatcctc agcaaaggcc attaattttt caagccttgt
    39841 cgcatcagtc aagtaagcat caccgataag ctctttaata tagtccgcca actcttggtt
    39901 ggcgaattct agccaacgac ggaaggtaat accattggtt ttgttgttga atttttctgg
    39961 atacagctca tagaaggcct tcaattcgct atttttcagg atttcagtgt gaagggcagc
    40021 aacgccgttg acacttgtgg caaaatgaat atccatatgt gccatatgca cgcgacctgt
    40081 ttcatcaatg atttggacag ctggatctga tacccttgca cgaacaagag catctaattg
    40141 ctcgataatc gttaccagct gcggcacaac ctcattaagg aagtcaagag gccatttttc
    40201 caaggcttct gcaaggatcg tgtgattggt gtaaccatcc atcttttgaa ccactgaaac
    40261 agcctcatca aaatcaaagc catgcttttg tgtcaataga cgaatcaatt ctggaatgac
    40321 cattgatgga tgggtatcat tgatctgcac gtatgcgtaa tcagctaagt catgcaggtt
    40381 tgagccacgc tcaagcgctt catcgatcaa gagctgagcg gcattagata ccatgaaata
    40441 ttgctggtaa atgcgaagga gctcaccatt tttatcagaa tcatcagggt aaaggaacag
    40501 ggtcaggttt ttggcaatgt cagtcttatc aaatgaaatg ccatctttaa tcaagccata
    40561 atcaacccct tcaatatcaa aaaggttaag atagttcttg gtgtcacgct tatagcccaa
    40621 aacatcaata cggtctaagc gagatttcag ggtaaagttt ttaaagggaa catcatatga
    40681 aatgtcagtc ggtactagcc aagagtcatc ctctatccaa aaattaggct ctgctgtttg
    40741 ttcattgtgt ctaaagacct gcttgaacaa gccacaatga taattcaagc caaccccttc
    40801 accattaatg ccaaggcttg agatagaatc aataaagcaa gaagccaaac gaccaagacc
    40861 accattacca agcgatggct ccaattcaac gtcctctacc tcagcaattg atttgcccgc
    40921 agcagccagc tcctctttga tgtccttata aatacctaga ttaatgagat tattagaaag
    40981 caacttacca atcaaaaatt ctgctgagat gtaataaacc ttacgtttag ctgtgttttt
    41041 tgcttttttg cttgcttctt ctttgagata ggaaagcaac gaaagataga tttcctcgtt
    41101 gcttgcactt gcaagagatt ttcctaatgt catttcagta taatctgtaa agcgtttcat
    41161 gatatcctct tttcaatata gtattctagt gatgattatt ggctcgaccg tatagctcag
    41221 tcaaatggat taaataggcc ttgtgctctg ctttaatatc gtcctcaagc atgcgccact
    41281 gccagttgcc accgacagtg tttggcatat tcatgcggct atcagctgac ttatccagca
    41341 aatcctgcat acacaggata gcagtatcac acacagtcgc aaagattgtt cttagcatgg
    41401 ccttggtgat gctttcagca gctgccttat ggatataatg attaacaaac tcaacctgct
    41461 ctgcgctcaa gtgctcatac cagccattca ccacctcatt gtcatgcgta ccagtgtaga
    41521 caatgcaatt gtgatcatag ttatgcggca aatcaaagct ttgacttgtc acatcaaaca
    41581 aaccaaactc taaaatcttc atgcccggaa agccagtaga tgccagcagc tgctcagcct
    41641 tttcatcaat gtagccaagg ttttctgcga taattggcag ctcacccaag gcctctcgaa
    41701 cagctttaaa tagagcaata ccaggagctg actcccaatg accattttta gcagtcacat
    41761 caccaccagg aatttcccaa aaatctgaga agcccttgaa atggtcaatt ctaagcttat
    41821 cgtacagctt gaagctctct ttgatccgat ggatccacca agcaaagcct gtttgctcat
    41881 ggctctccca gttgtaaata ggattgcccc aaagctgccc gtcctcacta aagccatcag
    41941 caggtacacc tgcaatgtaa atcggctttt tatctgcatc caccttaaag agctctggca
    42001 tcgtccaaac ctcaacgcta tcagcagaca cgtagattgg catatcacca atgatagtaa
    42061 tgccattttg attagcatag gtcttcagcg ctagccactg ctgataaaag aaatattggc
    42121 agaccttatg ataggtgatg cctttggcca acagcttgcg gtaatgaagc aaggcagcct
    42181 cttcacgctt aacaattgct ctatcgtccc attcctggag ggccttgtga tcaaaatgct
    42241 ctttaatagc cataaattca gcaaaatcat ttagccagct cgcagttgct tcaaattcgg
    42301 cgagctgtct taagccttcc tcagttgaga caaaagcctg aactgctttt tctaataaag
    42361 ggcgtctggc ttgaaagact tgagcgtaat caacagactc cggatttgag ccaaaatcaa
    42421 cagcagcata atcagcttcc tgcaaataac cgtcctttgc cagcaattca aggtcaataa
    42481 aatgcgtatt tcctgcaata gctgaaaaag attgataagg agaatctcca aagctagttg
    42541 ttgttaaggg caaaatctgc caataggtct gcttggtttc ctttaaaaag tcaacaaatt
    42601 caaaggcctc tttaccaaag ctcccaatac cgaagcgtcc cggaagcgag ctgatatgca
    42661 tcagaatacc acttgcacgt ttagtcattc tttttttctc cttgtaaaat cttaatgttg
    42721 aaattataac gcaaccgttt gcgcaagtca atatcttttc aaaaaaaaaa gagacttttt
    42781 cggcatgcta gagctgctca agccttgata ataatgaggg aagcagctag gacaaaaaca
    42841 aaaaaaggat tggagagaca gcctaagcag ctgctcttcc atcctcatct cactcctatt
    42901 tggcattaat atccctgaca ctctctcgct ttttgaggct aaagggaacc aaaattttct
    42961 gactcagggt ttgttcattg gcattgataa tgtctaagag ctgcctaaag gaggttcttc
    43021 ccaaattttc aacgttaata tcaaatgttg ttaagtaagg gtgaatcaat ttcgaatagc
    43081 tagaattatt aaaggtaata atcgaaatat catctggcac cttaatgtca taaaaggaca
    43141 agagctggac cattcgcacc gacaaaacat caccaatcac gattaaggct gtggccttaa
    43201 agctacgtat cgtttcaata accttttcga tgcttattgg atcctttcga tcaaataaca
    43261 gcatcggttt gttttccaag gataatttca agcagccctt gagatagcca atatagcgct
    43321 cagaagctac ctctgcctcc atatcgtctg tgataaacag gatctgtcgg tgaccctttt
    43381 gatagagatg atcaactgcg gttttagcca ttagctggtt gtcattgtca atataggtga
    43441 ttttgttctc atcaccttct ggtgcgccaa caatgacaaa aggaatctgg ttggtcatca
    43501 aatagcctct aacaggatct tcttgctcag aatataatat aataaagcca tcaacacgct
    43561 tttgcaggtg cattaactta acctggctca ataaatcctc aacagacata cctgttgcaa
    43621 tggaaacagt gaaatgatgt ttcttagctt cattggtaat ggtcgataga atttccataa
    43681 aaaagggatc actcaaacga tcattagtga taatcggcgg aaaaaccagg ccaatattat
    43741 gtgtcaggcc actagcaagc atttgcgcag ctacattcgg aacatagcca agctcgctca
    43801 tagctcttct aaccttttcc tttgtctttt gggagataga tcgattatcc ttgaggacac
    43861 gactgacggt cgaaggatta acacctgctt ttaaggcaac gtcttttatt gtaaccatat
    43921 aaacctcatt taatacctga taatgacgct atgtcaggct ttttcacatg tattttgctt
    43981 ttattataca attatctcct aaaaaatcaa ctctcgccct gcaagaaggc gacataaaaa
    44041 actgctgtcc tcatgatcga aaaaatgtta aaaaaatcaa ctttttttaa aaaaagacta
    44101 gactttttct gtaaacggtt gcataatatt aagtgtaaga aatatatctt aggaggaaat
    44161 cgctatgaaa tcatggcaaa aagttatcgt cagtggggca agcttgacac ttgctagcgc
    44221 cttattagta gggtgtgcat ctggttcaaa ggacaaaaca gaaactgcat caggtactga
    44281 ttcaaaaaca attaagcttt gggtaccaac aggagctaaa aagtcataca cagatgttgt
    44341 cgctaaattt gaaaaggact ctggctacaa ggttaaggtg atcgagtcag aggatccaaa
    44401 agcacaagaa aaaatcaaaa aagatgcttc tactgctgcc gatgtctttt cacttcctca
    44461 tgaccagctt ggtcagctcg tagaatctgg cattatccaa gaagtcccag aggaatacac
    44521 taaagagatc gctgatacag caactgatca agctatcctt ggtgctcaat acaagggtaa
    44581 aacctatgcc ttcccatttg gtattgagtc acaggttctc ttctacaaca aaactaagct
    44641 agctgctgat gatgttgctt catacgatac catcacgtct aaggctacct tcggtggtac
    44701 cttcaagcag gctaatgctt atgctactgg tccattgttc atgtctgttg gtaacacatt
    44761 atttggtgaa agcggtgaag acactaaagg aactaactgg ggcaatgaaa aaggggttgc
    44821 tgttcttaaa tggatttcag accaagcctc aaacaaagga tttgttaact tagatgccaa
    44881 caacgtcatg tctcagtttg gagacggttc agttgcttca tttgaatcag gtccttggga
    44941 ttacgaggca gcacaaaagg ctatcggtaa agaaaacctt ggtgttgctg tttatccaaa
    45001 ggtaactatc ggtggcgaaa ccgttcaaca aaaggccttc ttgggagtga agctctatgc
    45061 ggttaaccaa gctcctgcta agggagatac caagcgtatc gcagccagct acaagcttgc
    45121 ttcataccta acaaatgctg aaagccaaga aaaccaattc aagacacgta acatcgtacc
    45181 agctaacaag accgttcaag cttcagaggc tgttcaatca aacgagcttg caaaaacagt
    45241 tatcacaatg ggatcttctt cagattatac tgttgttatg cctaagctta gtcaaatggg
    45301 taccttctgg actgaaagtg ctgcaatcct tagcgatgcc ttcaatggta aaatcaaaga
    45361 aggtgactac cttgctaagc tacagcagtt tgacaaggac attgcagcaa caaaataagc
    45421 tatctcattt ataatactat cctaaacaag tacagaggtg ggctatttta acgctatcct
    45481 ttctactcat ctctaaaggg gtggaactaa gcatcattat tttttcaggg cttagtccac
    45541 tcctacttgt ttttgatatg acgtaaagct tggtgctact taaattttta atcgcttaaa
    45601 gatttaggta acacttagct atgtggtcgt tagcaccaaa cgcttatgac cacagcatct
    45661 gaacaagaga gtcaggtaat cctactttct tgtatcctaa cataaaggag aacatatatg
    45721 actcaggcag gcttagcatc tcaggttact gtaaaagagg ctttaacaaa gggaagcttc
    45781 gatattaaac tatccgctat catcatgggc tttgccaatt ttgctaataa acaattcgtc
    45841 aaaggaacac tctttttatt gagtgaggtg gtctttttca tcgcctttgt ttcacaaatc
    45901 attcctgcta ttggcggcct cattacccta ggaacacaaa cacagggcat gacaaccaaa
    45961 actatcgacg gtatcagcat tcaggttgct gttgatggag acaattcgat gctaatgctg
    46021 atttttggct tagcctctct gattttttgt ttgttatttg cctatattta ttggtgtaac
    46081 ctaaaaagcg cccgtcacct ctacatgcta aagcaagaag gggcaaaaat cccaagcttt
    46141 aaggaggatt ttgttagtct agcaaatggt cgtttccata tgaccttgat gacaattcca
    46201 ttgattggtg tgcttctgtt tacggtactt cctttgatct acatgatttg cttagcattt
    46261 actaactttg atcacaatca cctcccgcca aagtcacttt ttgattgggt tggtctttcc
    46321 aattttggta acgtgttaag tggtcgtatg gcaggaacct tctttcctgt tttctcatgg
    46381 acactgattt gggctgtctt tgccacagtg actaacttct tctttggtat cattttagca
    46441 ctcttgatta ataccaaagg cttaaaattg aaaaaaatgt ggcggacctt ctttgtgatt
    46501 accatcgcag ttcctcagtt tatttcactg ctgattatgc gaaatctgct aaatgaccaa
    46561 ggtcccttaa atgccctgct tagcaaatta gggttaatcc accattctct accgttttta
    46621 tctgatccaa tttgggctaa attctctatt atttttgtta atatgtggat cggtattcca
    46681 tttaccatgt taatcgcaac aggtatcatt atgaacctgc caagcgaaca aattgaggct
    46741 gcagagattg atggggcaag taaattccag gtcttcaaat caatcacctt ccctcaaatc
    46801 ctcattatca tgacaccaaa cctgattcag caatttattg gaaacatcaa taacttcaat
    46861 gtgatctatc tcttaactgg tggtgggcca accaattcag cctattacca agctggaacc
    46921 accgatctat tggtgacttg gctctataaa ttgactgtta cagcagcaga ttataatcta
    46981 gcctctgtta ttggtatctt aatctttacc gtatcagcaa tctttagctt actggcttac
    47041 acaagaactg catcatacaa ggaaggagca gcgaaataat gaaaaacaaa cgtcgatttc
    47101 agcttggatt agtttacgcc attttaaccg ttctctcaat catttggctt ttacctatcg
    47161 cttgggttgt tctgactagc tttcgtgctg aaggcactgc ttatgtcgat tattttcttc
    47221 ccaagcacct cacattagac cattatatta agctctttac aaatgaaaca tttccttttg
    47281 ggagatggtt tgtcaatacc tttgttgttg ctatctttac ctgtatcatc tcaaccttta
    47341 ttacagtggc gatggcttac tcgcttagtc ggatcaaatt caagtttcgc aatcgtttct
    47401 taaagcttgc actagtgcta aacatgtttc caggctttat gagcatgatt gctatctact
    47461 atatcctaaa agcacttggc cttacgcaaa gtcttaccgc cctagtcctt gtttattctg
    47521 ccggtgctgc acttggattt tacattgcta agggcttctt tgataccatt ccttattcgc
    47581 ttgacgaatc tgccatgatt gatggggcta ctcgtatgga tattttcttt aagattaccc
    47641 taccgctatc aaagccaatc attgtttaca ctgcactcct tgcctttatg ggaccttggg
    47701 ttgactttat ctttgcccaa gtgattttag gagatgcaac cagcagatat acggtagcta
    47761 tcggactctt ttcaatgctg cagcctgaca ccatcaatga ctggttcatg gcctttaccg
    47821 ctggatctgt gttaattgct attccaatca cattgctctt tatgtttatg caaaaatact
    47881 atgtagaggg cgttacaggt ggttctgtca aatagcagta atgatcacga taacccttac
    47941 tcaaaaaatc cttccc
//
LOCUS       DARYXS010000005        46574 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.005, whole genome shotgun sequence.
ACCESSION   DARYXS010000005 DARYXS010000000
VERSION     DARYXS010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46574
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.005"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            42..1034
                     /locus_tag="TV193_000202"
                     /pseudo
     CDS             42..1034
                     /locus_tag="TV193_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
     gene            1206..1745
                     /gene="rsmD"
                     /locus_tag="TV193_000203"
     CDS             1206..1745
                     /gene="rsmD"
                     /locus_tag="TV193_000203"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEL1512444.1"
                     /translation="MRIVSGEFGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFKGGR
                     VLDLFAGSGGLSIEAISRGMSEAVLVERDRKAQAIIQANIKMTKASQQFTLLKMNAER
                     ALDHLSGQFDVVFLDPPYAKETIVANIEALVEKNLLSDDVMIVCETDRSVALPEAIAW
                     LGIWKEKQYGISKVTVYVR"
     gene            1735..2235
                     /gene="coaD"
                     /locus_tag="TV193_000204"
     CDS             1735..2235
                     /gene="coaD"
                     /locus_tag="TV193_000204"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEL1512445.1"
                     /translation="MSGKIGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQ
                     SFFTFELRAQMLSEAVCALPNVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEI
                     GLEYFNHRLAPDIETIYLMATHDLQPVSSSRIRELIAFRAPITGLVPQAVINQVEKMN
                     ENNKKN"
     gene            2213..3250
                     /locus_tag="TV193_000205"
     CDS             2213..3250
                     /locus_tag="TV193_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEL1512446.1"
                     /translation="MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSV
                     LTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTPFTEISTMEDTTGGYSDADYLRI
                     NRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
                     TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQV
                     ISGDEVDFSTGGVGGPSAGLMFTLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGG
                     AGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKAAKRLKTAMKIIPVK
                     TVQDAISYLKK"
     gene            3812..4426
                     /locus_tag="TV193_000206"
     CDS             3812..4426
                     /locus_tag="TV193_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEL1512447.1"
                     /translation="MKRDILPEMYNYNKFPGPEFIHFDHYVKAEGIELLLLKNEKNAF
                     NTTSFGQRFTEILLKYDYIVGDWGNEQLRLKGFYKDHHDVKKASRISRLEDYIKEFCN
                     FGCAYFVLENPNPKDMPKEEERPSRRRKSSKANRRRNQPQHSQQAPAKDNFKKLTKDR
                     SADKPSFTSKKRPAPNKTKGNQRRSRTSQLNHKTDHFIIRKKDN"
     gene            4430..5512
                     /gene="rlmN"
                     /locus_tag="TV193_000207"
     CDS             4430..5512
                     /gene="rlmN"
                     /locus_tag="TV193_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEL1512448.1"
                     /translation="MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRVQSFDE
                     MTNISKEFVAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDKRAQDERVSHVVVM
                     GIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVS
                     LHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQE
                     LADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTMKKDRQKAAAART"
     gene            6794..7324
                     /locus_tag="TV193_000208"
     CDS             6794..7324
                     /locus_tag="TV193_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEL1512449.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDRLNANLDEMSERLITIGGAPYSTLEEFSQHSK
                     LDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGLDITDEEGDAASNDLFTAAKADAEK
                     TIWMLQAERGQGPAIF"
     gene            7697..7930
                     /locus_tag="TV193_000209"
     CDS             7697..7930
                     /locus_tag="TV193_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEL1512450.1"
                     /translation="MKTLYDVQQLLKGFGIVIYMGKRLYDIEMMKIELQRLYDGGLLD
                     KQAYLTAELILRREHRLELKREGQENESKIDRD"
     gene            7905..8876
                     /locus_tag="TV193_000210"
     CDS             7905..8876
                     /locus_tag="TV193_000210"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEL1512451.1"
                     /translation="MSQKLIGIDLGGTTIKFGILTSEGDVQEKWAIETNVLEDGKHIV
                     PDIVASLKHRLDLYGLTKDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIE
                     RELGIPFAIDNDANVAALGERWVGAGDNNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPLKGFACTCGSQGCLETVASATGVVKVARLLAEAYEGDSSIKAAIDNG
                     EAVSSKDIFVAAEAGDAFANSVVEKVSYYLGLAAANISNILNPDSVVIGGGVSAAGEF
                     LRSRVEKYFMTFTFPQVRQSTKIKIAELGNDAGIIGAASLARQFITE"
     gene            8886..9266
                     /locus_tag="TV193_000211"
     CDS             8886..9266
                     /locus_tag="TV193_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEL1512452.1"
                     /translation="MSPLTMIGWVLLAGVIAYYLWNYVSYRRMAKQVDNDTFKELMRQ
                     GQVIDLRDPASFRARHILGARNFPAQQFTTSIKALRKDKPILLYENVRPQYRVKAVKT
                     LRKAGYTDLYVLKAGLDYWNGKVK"
     gene            9662..11503
                     /gene="typA"
                     /locus_tag="TV193_000212"
     CDS             9662..11503
                     /gene="typA"
                     /locus_tag="TV193_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEL1512453.1"
                     /translation="MTKFREDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDDPADQEKTMAPIFDTIIDHIPAPVDNSAEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KVEERLLVELQTDVSLRVEPTESPDKWIVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVAGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            11585..11839
                     /locus_tag="TV193_000213"
     CDS             11585..11839
                     /locus_tag="TV193_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEL1512454.1"
                     /translation="MFYLIIAALITSYYLFMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPKEIFVGLAMIVLGYYALRDIQKIPKKPKSKH"
     gene            11985..13346
                     /locus_tag="TV193_000214"
     CDS             11985..13346
                     /locus_tag="TV193_000214"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEL1512455.1"
                     /translation="MKTITEFQNKKVLILGLAKSGEAAARLLARLGAIVTVNDSKPFE
                     ENPAAQALLEEGIRVICGSHPLELLDEDFYCMVKNPGIRYDNPMVVRALDKAISILTE
                     VELAYLVSEAPIIGITGSNGKTTTTTMIADVLNAGNHSALLAGNIGFPASEVAQAATA
                     KDILVMELSSFQLLGTEQFQPHIAVITNLVPTHLDYHGSFEDYIAAKWRIQHRMTDKD
                     YLVLNADQELVKSLAQKTKASPVFFSTKEKVDGAYLADGYLYFKEERLMSAAELGVPG
                     RHNIENALATIAVAKLRGISNQVISRTLSHFRGVKHRLQLVGTLNQVTFYNDSKSTNI
                     LACQKALSGFDNSKVILIAGGLDRGNEFDELVPDLVGLKKMILLGESAERMKRAADKA
                     GVSYLDAKDVAAATKIAFEQAKAGDIILLSPANASWDMYPSFESRGDEFLAAYDALKG
                     EAQ"
     gene            13343..14425
                     /locus_tag="TV193_000215"
     CDS             13343..14425
                     /locus_tag="TV193_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEL1512456.1"
                     /translation="MTKKIIFTGGGTAGHVTLNLILIPKFIKDGWEVHYIGDDKGIEH
                     QEIKKSGLDVTFHAIATGKLRRYFSWQNLLDIFKVGFGVMQSLFIIARLRPKALFSKG
                     GFVSVPPVIAARLLGVPAFIHESDLSMGLANRIAYRFATTMYTTFEQEQTLAKLKHVG
                     AVTKVTGPGSRSVTSKQLEAVLEYFDPNLKTLLFIGGSAGARVFNRFITDHPELKEDF
                     NIINISGDPSLNELSWHLYRVDYVTDLYQPLMEMADLVVTRGGSNTLFELLAMRKLQL
                     IIPLGKEASRGDQLENAHYFTTRGYAEQLLEQELTLPHFQEKVREVFAKQSDYLSAMK
                     SSSELQSPESFYQLLSADISSATKEN"
     gene            14426..15616
                     /locus_tag="TV193_000216"
     CDS             14426..15616
                     /locus_tag="TV193_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HEL1512457.1"
                     /translation="MADKTKHSEEKAALTEWQKRNIEFLNKKQQQAEKDKKLKEKLLN
                     EKIAQAQGEAASKADQEDTDEAEEKTEVSQAGTDEGEPLPEASEQEVPSPKDKPLKVP
                     KEKSPKQQALQKGWPVLLVSFVVLCLSIFMITPYSKVKDFSVKGNKKTSVEDLVRDSG
                     IKSSDYWITLLASPGSYENAVLKANPWVKKVALRYGFPNHFRFDVTEFDIIAYAQVAE
                     GFQLILENGKRVAAVKQAALPKSFLILNLEHEKEIQDVINRLTKIPSDLVKAIKSVSS
                     ANSQTTKDLLLLEMHDGNLIRVPRSQLELKLPYYQKIKKNLDTASIVDMEVGIYTTTA
                     EIENMPEVPASAQASQADKPAEASPEQGEEQATQEQPSPETPANPEATNPSVAQPTEQ
                     ANQQ"
     gene            15828..17192
                     /gene="ftsA"
                     /locus_tag="TV193_000217"
     CDS             15828..17192
                     /gene="ftsA"
                     /locus_tag="TV193_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEL1512458.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVD
                     VVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLR
                     RKPIDFTGQEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFG
                     SMFD"
     gene            17216..18544
                     /gene="ftsZ"
                     /locus_tag="TV193_000218"
     CDS             17216..18544
                     /gene="ftsZ"
                     /locus_tag="TV193_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEL1512459.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVVQLGPKLTRGLGAGGQPEVGRKAAEESEEVLTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRSNFAIEGIQELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDSMRDEIRVTVVATGVRQDKAEQASGFRQPRTYT
                     QSNAQQAAGAQYASEQVRQTAQPSFDRRSSSFDFDMGETREMPKSQQAMPAHGHNHNQ
                     GSAFGNWDLRRDNIARPAEGELDNQLNMSTFSSNDDIDDELETPPFFKNR"
     gene            18547..19218
                     /locus_tag="TV193_000219"
     CDS             18547..19218
                     /locus_tag="TV193_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEL1512460.1"
                     /translation="MDLQKNKDIVFENIRLATQAANRPENSVSVIAVTKYVDKAVAGQ
                     LIDMGIEHIAENRIDKFLDKYEALKDRQVTWHFIGTLQRRKVKEVINKVDYFHALDSV
                     KLALEIEKRADHPVKCFLQVNISEEESKHGFKIAELDAAIEEISKMEKLHLVGIMTMA
                     PIDASQQELRSIFQKANQLRKNLQSKKRKNMPFTELSMGMSNDYPIAIQEGSTFVRIG
                     TSFFH"
     gene            19231..19893
                     /locus_tag="TV193_000220"
     CDS             19231..19893
                     /locus_tag="TV193_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEL1512461.1"
                     /translation="MAIKDAFNKMISYFDTDGVSEVEEELSSKKQEEPVTKSQQTSRP
                     NQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAYAERPYQGQSQARVSHDYNDRRA
                     TSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDA
                     QARRCLDFIDGASKVLYGTLQRVGSSMYLLTPSNVSVNIEEMNIPNNGQDIGFDFDMK
                     RR"
     gene            19898..20155
                     /locus_tag="TV193_000221"
     CDS             19898..20155
                     /locus_tag="TV193_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEL1512462.1"
                     /translation="MIFILLILLKLIKVYSYLLLVYALLSWFPGAYDSWLGRLVSDIV
                     EPILKPFRSLNLQFAGLDFTIYLVMIGLNVLSEILIRVLIS"
     gene            20152..20946
                     /locus_tag="TV193_000222"
     CDS             20152..20946
                     /locus_tag="TV193_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEL1512463.1"
                     /translation="MTVQTMLYQHFQPDEHPFIERMLDLIARVEANYLLEVTDFLNPR
                     EVTILKGLVAATNLQCFSSTDYYPSEYGRVIVAPDYYCLDKADFDLALIEVTYNAKFN
                     QLTHAQILGTLINELGIKRALLGDIFVEIGHAQVMINRQLLSYCLGTIAKIAKARVKL
                     KEIDLDQLLNLTANQQVLTDIMVSSLRVDRLIATVLKQSRNQAIRLVEAGKVKVNYQL
                     VTKASQPVAVGDLISIRGYGRFSILTDNGFTKNGKYKLTLSKMMRK"
     gene            20956..21711
                     /locus_tag="TV193_000223"
     CDS             20956..21711
                     /locus_tag="TV193_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEL1512464.1"
                     /translation="MALTALEIKDKTFKTKFRGYSEEEVNEFLEIVVDDYEALVRKNR
                     DNEAKIRELEEKLSYFDEMKESLSQSVILAQETAEKVKSSANAEATNLVSKATYDAQH
                     LLDESKAKANQLLRDATDEAKRVAIETEELKRQTRVFHQRLVSAIESQLSLSNSPEWD
                     ELLQPTAVYLQNSDAAFKEVVKTVLNEDIPEADDSNSFDATRQFTPEELEELQRRVEE
                     SNKELEAYQVQREEQASEPEVNLSETQTFKLNI"
     gene            21982..24780
                     /locus_tag="TV193_000224"
     CDS             21982..24780
                     /locus_tag="TV193_000224"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEL1512465.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQKAWDEAEIYKKRQALN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRAKSMSGYQAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLADYLDMCRQYALSQVDKQRDDFKRLGVSADWDNPYVTLDPSFE
                     ADQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGK
                     GILDTDTYVVVWTTTPFTVTASRGLTVGPDMDYVVVRPAGSDRNYVVAEGLLDSLAAK
                     FAWESFEILANHKGSDLEYIVTEHPWDSEVDELVILGDHVTLDSGTGIVHTAPGFGED
                     DYNVGMTYGLEVAVTVDERGLMMENAGPDFHGQFYGKVTPIVIEKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQEILDEIDKTTFHPTWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQEHGSIIWWQKEAKELLPEGF
                     THPGSPNGVFTKETDIMDVWFDSGSSWNGVMNARDHLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMDILGQVSETYRKIRNTLRFLLANTSDFNPHTDKVAYAELAAVDKYMT
                     IKFNKLVGAINTAYERYDFMTIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLARRR
                     MQTVFYDILVNITKLLTPILPHTAEEIWSYLEHEPEDFVQLSELPQAQTFDNQDTILE
                     EWEAFMTLRAQAQKALEEARHDKIIGKSLEAHLTIYASPEVKTLLTALDSDIALLLIV
                     SQLTISEEPAPENAVSFDDVAFTVARAQGEVCERSRRIDPTTRMRSYNAFVCDHSAKI
                     IEENFPEAVAEGFDSAAN"
     gene            complement(25258..25560)
                     /locus_tag="TV193_000225"
     CDS             complement(25258..25560)
                     /locus_tag="TV193_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEL1512466.1"
                     /translation="MRLINTTSSHPELVRNQLQNTDAHLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELEVIREFFLKRKIDQSIVIPGHSKTLHTNNLIEISFQTSV"
     gene            complement(25622..26071)
                     /locus_tag="TV193_000226"
     CDS             complement(25622..26071)
                     /locus_tag="TV193_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1512467.1"
                     /translation="MTVPIFGDKIDDQHYTARYGVYAVIPNSAKTEIILVQAPNGAWF
                     LPGGEIEAGESQLQALERELVEELGFAADIGYYYGQADEYFYSRHRDTYYYNPAYLYE
                     VTSFQAISKPLEDFNHLAWFLPIADAITVLKRDSHRWGVEEWQKKHH"
     gene            complement(26231..28483)
                     /locus_tag="TV193_000227"
     CDS             complement(26231..28483)
                     /locus_tag="TV193_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1512468.1"
                     /translation="MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPI
                     LGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLPNTPPTQSGGHNGGGHNGYRPNH
                     TQPAQEANKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
                     PGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEE
                     IRKRHDVILFIDEIHEIVGAGAVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIE
                     KDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQSAIEAAANLSNRYIQ
                     DRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFR
                     DQIAKYKEMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLK
                     KHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFGS
                     ADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLDEIEKAH
                     PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNS
                     VLGELSHFFSPEFMNRFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQK
                     VKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLEHPAEKDMRAVLTSNGHIIIKP
                     VVKSQAKQAD"
     gene            28765..28995
                     /locus_tag="TV193_000228"
     CDS             28765..28995
                     /locus_tag="TV193_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEL1512469.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFVNDPEN
                     GPVFILRDIEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(29477..30415)
                     /locus_tag="TV193_000229"
     CDS             complement(29477..30415)
                     /locus_tag="TV193_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1512470.1"
                     /translation="MKKTIRKYSVCSAAIALATMASLGTAGNARAEDYTRLESYPDPA
                     ELIRDGLGDGEVRVYLHTLRQFMQTYLQNLELQAKKGGPQGPVGPAGPRGERGEQGPV
                     GPMGPRGDKGETGETGPKGEQGPAGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQG
                     QRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQKPKGDQGKDTKPSAPKAPEKTPAPKAPEKSAQPKAPAPKSAPAAQ
                     KSTLPATGETNHPFFTLAALSVITSAGVLNLKKKKS"
     gene            30757..31440
                     /locus_tag="TV193_000230"
     CDS             30757..31440
                     /locus_tag="TV193_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1512471.1"
                     /translation="MDFTFLPKYWAYFNYGVLVTMMISACVVFFGTIIGLLVTLIKRS
                     HIKPLSWLVSLYVWIFRGTPMVVQIMIAFAWLHFNDLPIVGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPKNAMRYVILPQAFKNILPALGNE
                     LITIIKDSALLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMITTILSQLLGCL
                     ERKLAQGGR"
     gene            31442..32179
                     /locus_tag="TV193_000231"
     CDS             31442..32179
                     /locus_tag="TV193_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1512472.1"
                     /translation="MTETVISIRQLHKSFGKHEVLKGIDLTINQGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGHISFEGVDITDKANDIFKMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMSRAGAEQRAYELLERVGLRDKAAAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGLV
                     IEEGSPVQVFEAPKEERTKDFLSKVLS"
     gene            32623..34317
                     /locus_tag="TV193_000232"
     CDS             32623..34317
                     /locus_tag="TV193_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1512473.1"
                     /translation="MDYKAVYQEWLHNDFFNEEIKADLEAIKHDEAEIQDRFYKVLEF
                     GTAGLRGKLGAGTNRMNIYMVGKAAQALANTIIDHGPEAVSRGIAISYDVRYKSKEFA
                     ELTCSIMAANGIKSYIYKGIRPTPMCSYAIRALNCISGVMITASHNPQAYNGYKAYWE
                     EGSQILDDIANQIAVHMDAIERFEDVKQIPFEEALASGLTSYIDDSIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLKRRGFDHVFVVPEQEMPDPDFTTVGYPN
                     PEVPKAFAYSERLGQEVGAAILIATDPDCDRVALEVRAADGSYVFLNGNKIGALLSYY
                     IFSQRHARHNLPDNPVLVKSIVTGDLSKAIAAKYDVETVETLTGFKNICGKANDYDIT
                     KEKTYVFGYEESIGFCYGTFVRDKDAVSASMMVVEMAAYYKQRGQSLLDVLQDIYKEF
                     GYYNERQVALELEGVEGQKRIARIMEDFRNEPIEHAGAMSLKTIVDFKDGYLDFPKQN
                     CLKYYFDDGSWYALRPSGTEPKIKLYIYTIGETEADSIAKLDAIESACQAKMDSVS"
     gene            34429..35283
                     /locus_tag="TV193_000233"
     CDS             34429..35283
                     /locus_tag="TV193_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEL1512474.1"
                     /translation="MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNP
                     ASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPH
                     HINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFHDYGIELEGKN
                     AVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRRLADICRRADILIVAIGQGHFITKE
                     FVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSELASMITPVPGGVGPMTITMLLEQTYQ
                     AALRRVSQ"
     gene            35280..36134
                     /locus_tag="TV193_000234"
     CDS             35280..36134
                     /locus_tag="TV193_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEL1512475.1"
                     /translation="MIIDQSFVARVVVPRQADSHKGSYGRVLLVGGLYPYGGAIIMVA
                     LACVHSGAGLVTVATDRETIAALHSHLPEAMAIAVDDEELLLSQLGMADLILIGPGLS
                     ENSRAARLFELVLAHVADHQVLVIDGSALRLLAKRAADVKQLRCPLVLTPHQKEWEAL
                     SGLAIDQQYDAANQAALKHFPRATILVAKSSATKIYHGNQIYRLRVGGPYQATGGMGD
                     TLAGMIAGIAVQFPESSLVAKVACATYLHSAIADELAKTAYVVLPTAISYELPRWLKA
                     ISTGQKLG"
     gene            36418..37758
                     /locus_tag="TV193_000235"
     CDS             36418..37758
                     /locus_tag="TV193_000235"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEL1512476.1"
                     /translation="MADYLSVTQLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPNHQY
                     FSLKDEGAVIQATMWAGAYKKLGFDLEEGMKLNVVGRIQLYEPNGSYSMIIEKAEPDG
                     IGALALQFEQLRQKLAGEGFFDERHKQALPQFVTKVGIVTSPSGAVIRDIITTISRRF
                     PGVSILLFPTKVQGEGAAQEVAANITKANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDIVSWIAEQQS
                     RSYQACLRYIRQGQERVDKLSYSVIFRQPERLYDAYSQRLDRLTTSLMTTFKETLSGA
                     KQEHLILEHRLASVNVQARLERYQDRLATAHRLLIANMTNQYDSKLAGFERAQAALLS
                     LDTSRIIARGYALLKKDGVVAACVKDIKKGDHLSIIMRDGQLEVEVEDVNEKNI"
     gene            37736..37951
                     /locus_tag="TV193_000236"
     CDS             37736..37951
                     /locus_tag="TV193_000236"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEL1512477.1"
                     /translation="MSTKKIFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKD
                     LQKTLQAAEKTLVKVMQADGTELEMDA"
     gene            37951..38820
                     /locus_tag="TV193_000237"
     CDS             37951..38820
                     /locus_tag="TV193_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEL1512478.1"
                     /translation="MDKLTRINATIHQYYDRQSTVSADLEEAILYSVDGGGKRLRPLM
                     LLELLEGFGLALTDAHYAVAAAVEMIHTGSLIHDDLPAMDNDDYRRGRLTSHKQFNEA
                     TAILAGDSLFLDPFALIAGADLPADLLVQLIQQFSLASGTFGMVGGQLLDMKGEHQLL
                     DIQELSDIHANKTGKLLTLPFVAAGIIAEQSADVLSCLWEAGRLVGQAFQIRDDILDL
                     TASFADLGKTPQKDLAAAKSTYPSLLGLERSRAILEESLSQALAIFSRLEREEGFESQ
                     AIIKRIEGLRLNG"
     gene            38813..39640
                     /locus_tag="TV193_000238"
     CDS             38813..39640
                     /locus_tag="TV193_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEL1512479.1"
                     /translation="MAKERVDVLAYRQGLFETREQAKRGVMAGLVISAISGLRFDKPG
                     EKIDEGIELRLKGEKLKYVSRGGLKLEKALQVFGISVQDKVTIDIGASTGGFTDVMLQ
                     AGARLVYAVDVGTNQLVWKLRQDSRVRSMEQYNFRYAKLADFSEGQPAFASIDVSFIS
                     LSLILPTLHCILQEGAEAVALIKPQFEAGREQIGKKGIVKDRLIHEKVIKQVADTALN
                     CGFIVKGLDFSPIQGGHGNIEFLAHLVKGKGSKAIDDQLIQSVVSSAHKEFKQHEKE"
     gene            39627..40097
                     /locus_tag="TV193_000239"
     CDS             39627..40097
                     /locus_tag="TV193_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1512480.1"
                     /translation="MKKSERLDLIKKMVLSHEIETQHELLKLLADYGLELTQATISRD
                     MNEIGIVKIPSGTGRYVYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVV
                     PGNSKLIKRYLMTDFSGQLFSLIADDDSLLLIAKSEADADHIRQELSLWMQGLV"
     gene            40115..41776
                     /gene="recN"
                     /locus_tag="TV193_000240"
     CDS             40115..41776
                     /gene="recN"
                     /locus_tag="TV193_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEL1512481.1"
                     /translation="MLLEISIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     LLGARASTEVIRHGADKAEIEGFFSVDANPHLAAVLAESGISMEEELILRRDIFANGR
                     SVSRINGQMVTVSTLKKLGQFLVDIHGQHDQEELMRPQLHQHILDSFGDEAFDQLKQS
                     YQQIFDRYKALRRQALEKQKNEKEHQARLDLLAFQIGEIEAADLVRGEDDLLNQERQR
                     LLNHKKIADTLTSAYLSLDNEDFSSLSQVRSSMNELLSIEDLAPEYQLISAGVSEAYY
                     ILEEVTKQLSDTIDQLDFDAGRLQDIELRLDSINSLTRKYGGGVNDVLDYYANITKEY
                     QLLSGDDRSSDELERELKVLEKQLVMTASQLSDKRHALALELEADIKAELRELYMEKA
                     DFKVHFTRSKFNREGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAKKIYKIGSYGQVLAISHLPQVVAIADNQYFISKES
                     KEESTVSKAKLLTQEERIEEIAKMIAGADVTETARNQARELLGKD"
     gene            41997..42869
                     /locus_tag="TV193_000241"
     CDS             41997..42869
                     /locus_tag="TV193_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1512482.1"
                     /translation="MLKKRMGLASLLVLMTFVYQCCSVTAEQYSDTEVEVLQISEEKS
                     QIMENQEALKDLTTSSDQLKKEALKPKEAATNKSKQEASTVYLAEDDPVTIDSSDEES
                     NQDIIADSVPDLVIKGDQVDVSEVMVSVKEDSSKVAKQRTDAAQRYSIAKHQLTQKLE
                     AFNAATDQLLTMIAKKSDLTGQYYVVGHSLGEMLAAQNEKKLAEQLVMQQKHKKGLGS
                     SVTILDELGRVISDISGHKGMLPFNRKISFKVHQVRYDLPLTGDRTVLPAQLAGLLLL
                     LIGLMLPKVANKKS"
     gene            43007..43858
                     /locus_tag="TV193_000242"
     CDS             43007..43858
                     /locus_tag="TV193_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1512483.1"
                     /translation="MELKMGTIKIVADSSMTIEPELIKSLDITVVPLSVMIDSKLYSD
                     NELKEEGQFLQLMRASKSLPKTSQPPVGLFADIYERLVKEGATAIVAIHLSPALSGTI
                     EASRQGAEIAAAPVTVLDSGFTDQALKFQVVEAARLAQAGASLEEILEAVEDIKRKTE
                     LYIGVSALEHLVKGGRIGRVTGLLSSLLNIRVVMEMKNDTLQTLVKGRGNKTFTKWLD
                     SYLAENSQRQIAEVAISYAGQRDFADSLKKTIATVFDGPITVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            43851..44693
                     /locus_tag="TV193_000243"
     CDS             43851..44693
                     /locus_tag="TV193_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEL1512484.1"
                     /translation="MNKRGFLGGLIFFFSVFALSFVILAVLIPKSDPQLKKSDFLKNK
                     KISLNYIAIGDSLTEGVGDLTNQGGFVPLLSGDLGDYFNATVNTENYGVSGNTSQQIL
                     TRMTENKEITEQLKKANLMTLTVGGNDVLAVIRKNLANLKVSSFKKPARQYQERLRKI
                     LDLARKDNQDLPIFVLGIYNPFYLNFQELTEMQTVINDWNKKTQEVVDDYDHVYFVPI
                     NDLLYKGVDGKEGIVQSTGEQTTIVNDALFSGDHFHPNNTGYQIMSDAVMETIRKNGK
                     EIKP"
     gene            44671..45258
                     /locus_tag="TV193_000244"
     CDS             44671..45258
                     /locus_tag="TV193_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEL1512485.1"
                     /translation="MEKKLNLNWWKWAFLLLLAFNAAFLAVIGSRIIQIREPKSELIN
                     QKAAKNIKIGTLTTTKEQLNEAVVSYLKDFQTEKMTYKVYATSSTILFEGTYQLLGYE
                     VPLYIYFQPHRLTNGAIQLQVLSFSVGTLSLPEKDVLQYLKSSYKLPKFVEVLPKQSA
                     IIINLQQLENDANIYLKAQKIDLVKDDIRFDIYKK"
     gene            45356..45631
                     /locus_tag="TV193_000245"
     CDS             45356..45631
                     /locus_tag="TV193_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEL1512486.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(45692..46396)
                     /locus_tag="TV193_000246"
     CDS             complement(45692..46396)
                     /locus_tag="TV193_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEL1512487.1"
                     /translation="MLVVQPSTIKAQSYDEGQTVVFEPYGNSFKPYYKFSEPDVTKYI
                     ITNRWRSQTAFTEAEKKMMYQYTYASASPINLALEQVMGDTSQLDAQLQQSVALLDSA
                     THKLTIPWNIIVYRYVYETFLTELGTSEEELARYYHDKTFDPQILSAIKPGTHYTKQG
                     FMSTTAIKNAAMPHRSVELRIQVPQGSQAAFVQPYSFYPYEMELLFPRQCTLEIIGAN
                     LSDDHTRLLIETRLLP"
BASE COUNT        12965 a         8787 c        11411 g        13411 t
ORIGIN      
        1 taaaggtgac ttagtcgcga aaatgattta aaggaggagc tatgaaaaaa agctttattc
       61 atcaacaaga ggaaatttcc tttgttaaaa atacatttac gcagtatttg attgctaagc
      121 ttgatgttgt tgaggtgcaa ggtcctattt taagtagggt cggagacggc atgcaggaca
      181 atttatctgg ggttgaaaat ccggtatctg tccatgtctt gaacattcct aatgcaacct
      241 ttgaggtggt gcattcgcta gcaaaatgga agcgtcatac cttagcacgt tttggcttta
      301 atgaaggtga aggtcttgtg gtgaatatga aagcgctccg tcctgatgaa gattcgctag
      361 accagacgca ttcagtgtat gtggaccagt gggattggga gaaggttatc cctgatggtc
      421 agcgcaatct agcttacctc aaagaaactg tcgaaacgat ttacaaggtt atccgcttga
      481 cagagctagc tgttgaggca cgctatgata ttgaagctgt cttgccaaag aaaattacct
      541 tcattcacac cgaggagctt gttgccagat accctgattt gacaccaaag gagcgtgaaa
      601 atgctatcac aaaagaattt gatgcggtat ttttgattgg tattggcggt gtattgccag
      661 atggcaagcc acatgacggt cgtgcgccag actatgatga ctggaccagt gagtcagaaa
      721 atggctacca tggcttaaat ggtgatattc tcgtttggaa tgagtagcta ggcacagcct
      781 ttgagctatt ctcaatggga attcgtgttg atgaagaggc tctaaagcgt caggtggaca
      841 ttactggaga tcaggaacgc ctacaatttg attggcacaa atcgctgcta aatggtctgt
      901 tccccctaac catcggtgga ggaattggtc aatcgcgtat ggccatgttt ttgcttcgta
      961 aaaagcacat tggagaggtc caaacatcgg tgtggccaca agaggttcgc gatacctacg
     1021 acaatatttt atagatgata cggaggctag gtttttacct atagcctcta tttttgtccc
     1081 taagtgatgc ttcattagag ctcatttagt gctaagcagg ctcgtcagtt atataatagg
     1141 tcaaaaattt gaaaaaatga atcattttta aggcttgaca ctagattttt gttataatat
     1201 cagttatgag aattgtatca ggtgaatttg gagggcgtcc cctaaaaacg ctcgaaggca
     1261 agactactcg acccacatca gataaggtac gtggcgcgat ttttaatatg attggtcctt
     1321 attttaaggg cggacgtgtc ttagacttgt ttgctggatc aggtggccta tcaatagagg
     1381 ctatttctag gggcatgtca gaggcagtgc tggttgagcg tgatcgtaag gcgcaagcca
     1441 ttatccaagc caatattaag atgacaaaag ctagccagca atttacgcta ttaaaaatga
     1501 acgctgagcg tgcacttgat cacttatccg gtcagtttga tgtggtgttt ttggacccac
     1561 cttatgctaa ggaaacgata gtagccaata tagaggcctt ggtggagaaa aatcttttaa
     1621 gcgacgatgt gatgattgtt tgtgagacgg atcggtcggt agctctgcca gaggcaattg
     1681 cctggctagg gatctggaaa gaaaaacaat atggaattag caaggtaaca gtatatgtca
     1741 ggtaagattg gactttatac agggtcattt gacccagtga caaatggaca catggatatg
     1801 attaagcgtg ctagccattt gtttgagcat gtttatgtcg ggatttttaa caatccaaat
     1861 aagcagagct tttttacttt tgagctgcga gctcaaatgc taagcgaagc ggtttgtgcc
     1921 ttgccaaatg tgacagtggt ttctgccgag catggtcttg cagttgacct ggctagggag
     1981 ctgtctgtga cccaccttat ccgagggctt cgcaatacag ctgattttga ctatgagata
     2041 ggcttagagt attttaatca tagactagcc cctgatattg agaccattta cctgatggcg
     2101 actcatgacc tgcagcccgt tagctccagt cgtatcagag agttgattgc atttagagcg
     2161 ccaattactg gtttggttcc gcaggctgtt attaatcaag tggagaaaat gaatgaaaac
     2221 aataaaaaaa attaaatggt ggctgattgg ctttgttgcc ttgctttttc tactgttgac
     2281 actgtttttc cccttgcctt attatattga aatgccaggt ggagcctatg atattcgctc
     2341 ggtattgact gtcaatggca aagaggataa ggaaaaggga gcttatcagt ttgttgtagt
     2401 gagcctcagt cgggccacct tggctaaatt gctctatgct tggctaacgc ctttcactga
     2461 gattagcacc atggaagata ctactggtgg ctatagcgat gctgactacc tgcgaattaa
     2521 tcgcttttat atggaaacct ctcaaaacag cgctgtttat caggccctta ctctagcagg
     2581 caaggaggta agctttgatt ataagggtgt ttatgtctta gacgtcagca aggattctag
     2641 ctttaaaggt gtgctgcacc tagcagatac agtgacaggt gtcaatggta aaacatttac
     2701 aacgtctgcc gatctgattg attatgtttc tcatttgacc ttgggagatg aggtgcaggt
     2761 acaatttaca accgctggtg agtcaaagac tgaaaaagga aagattatta agcttaaaaa
     2821 cggtaaaaat gggattggca ttaccctgac agaccacaca caggtcattt ctggtgatga
     2881 ggtcgacttt agcactggag gtgtgggtgg accaagtgca ggcttgatgt ttactcttga
     2941 tatttatgat caaatcaatc acgaagactt gcgcaaggga cgtgtgattg ctggtacagg
     3001 aaccattggc aaggatggaa aagttggaga tattggcggg gcgggcctaa aggtggctgc
     3061 cgccgccgct gctggtgctg atattttctt tgttccaaat aatcctgtgc ataaggacgt
     3121 caaaaaagca aatcctaagg ctattagcaa ttacgaggag gctaaaaaag cagctaaacg
     3181 actaaagaca gcaatgaaaa ttattcctgt gaaaaccgtt caagatgcta taagctacct
     3241 taaaaaatag aagcaatgcg aagcaggcta atagggcatg ctctgtcttg cttctagttg
     3301 gtggaattta gctagctcaa aggtcttgag acctaagcat aaggtctaga cagtattcta
     3361 gagctagacc ttatgcttga tcctgaacaa ggaagaccgc caaagaagaa caaaatcctc
     3421 aggccaaaag agcccgtagg gaaatattgc cattatctat caaggctttt tgaagaaaat
     3481 cacttaaaga cagtagggcg ttaggcttta ctgtcttagt ttttcttgcc tgaagtcatg
     3541 gctgctgatg atgttacatc aaggcttact agccagcaga gcacaaggag cagctttggc
     3601 ttaggtttat tttctctgct gactagtaaa gaaggttgct gtcagtctgc ttacaaaaac
     3661 ctaaaaatag tgtataatag gtaggctatg ggctgtcagg agtcgctagc ctgcttaccc
     3721 agaccagccc tttgagaaga gcaagcatgg ctcttctcag aataacccag gattaacaga
     3781 catcaaaatt aatgctaagg aaaggagcta tatgaaaaga gatattttac cagagatgta
     3841 taattacaat aaatttcccg gtccggaatt tattcatttt gatcattatg tcaaggctga
     3901 aggcattgag ttattgctgc tgaaaaatga aaaaaatgct tttaacacaa cgagctttgg
     3961 tcagcgcttc acagagatat tattaaagta tgactatatt gttggagatt ggggcaatga
     4021 acagctgcgt ctcaagggct tttacaagga tcatcatgat gtcaaaaaag ctagtcgtat
     4081 ttctcgccta gaagactata ttaaagaatt ttgtaacttt ggctgtgcct attttgtttt
     4141 ggaaaaccct aatcccaagg acatgccaaa agaggaggaa aggccatcaa ggcgcaggaa
     4201 atcgtctaaa gccaatcgcc gcagaaatca gcctcagcat agtcagcagg cacctgctaa
     4261 agacaacttc aaaaagctaa ccaaggatag gtcagcggac aagccaagct ttaccagcaa
     4321 aaagcgccca gctcctaata agaccaaggg aaaccaaagg cgctctcgta ctagtcaact
     4381 gaaccataaa acggatcact ttatcatcag aaagaaggac aattaatcta tgaaaccatc
     4441 aatctatggc ctaacgcgcg acgagctaat tgcttgggcg attgacaatg gtcaaaaggc
     4501 attcagagcg acacagattt gggactggct ttacagaaaa cgggttcaat cctttgatga
     4561 aatgactaac atttctaagg aatttgttgc cattctaaag gacagctttt gtattaatcc
     4621 cttgaagcag cgtgttgctc aggaatcagc tgatggaacg gttaagtatt tgtttgaatt
     4681 gccagatggt atgctgattg aaacggtttt gatgcgtcag cactatgggc agtcggtctg
     4741 tgtaactacg caggttggct gtaatatagg ctgcaccttc tgcgctagtg gcttgattaa
     4801 aaagcaacgg gatttaaaca gtggtgaaat cactgcacaa attatgatgg tgcaaaacta
     4861 ttttgataag cgtgctcaag acgaacgtgt cagccatgtt gttgtgatgg ggattggaga
     4921 gccctttgat aattatcaaa atgtgatgac ctttcttcgg acgatcaatg atgatcatgg
     4981 gcttgctatt ggtgctcgtc acattactgt ttcaacctca ggcttggctc acaagattcg
     5041 tgaatttgcc aatgaaggag tccaagttaa tctggctgtg tcactgcatg cacctaataa
     5101 tgagctgcgc tcaagtatca tgaggatcaa tcgttccttc ccacttgata agctcttttc
     5161 agcaatcgaa tattacattg aaacaactaa tcgtcgtgtg acctttgagt atatcatgct
     5221 taataaggtt aatgatgggg tagagcaggc acaggaattg gcagatttga ccaaaaggat
     5281 tcgcaagctg tcttatgtta acctgattcc ctataatcct gtctcagagc atgaccaata
     5341 cagtagaagt cctaaggagc gtgtggcagc cttttatgac attctaaaga aaaatggagt
     5401 gaactgtgtc gttcgtcagg agcatggtac agatattgat gctgcctgcg gtcagctgcg
     5461 ctctaatacc atgaaaaagg accgacaaaa agcagcagct gcaaggacat gatgacttgg
     5521 tcaaggttgc tgatttgatt gataggagat ggagataaaa atctgacctc aaataaagca
     5581 aacaaatagg tctagttttc tgagatcccg aaagcaggtc ttgttcgttt tttaatgaat
     5641 gagactaggt cataaagtac atgcgttaag aatgtctaaa gtgcagctct ttttgtccca
     5701 gcctccctct tttatcttgg tagcagttgt caagtaattg ctaagcaaca gtgttttatc
     5761 tttattggct gtaaaaaaag atatagtgcc tttattcaca ccttttctga atcacttgag
     5821 ccttgttctg accgctcctt ttggtgcttc tgatccatat agcctaagct tttcagagct
     5881 atgaatcgag gcaaaataat aggtgttagc cctagctgct tgatgtagct agggcttttg
     5941 tgacctagct gccagtgagc ctttcaaata gcaatatggc tataaggccc agtgtcagat
     6001 agggaataaa agggattttc ttagtttgta gaagtaggca ggctagaatt ccgatcagac
     6061 tggcaatttg gacgatccat aacaaagagc taagcttgac cacaagagca agattagcta
     6121 ggtaaagaaa atctccggca ccaatattga taggaaaagc tacgcttagc agtgcaagca
     6181 aaagcaatag cactgttaac aggttaatgc tataaaatgg cagcagaaac aaaaagctca
     6241 tcagccagat gagcaaagga tactcttgac tgtctaaatc aaaaaagcac agtagcaaag
     6301 agaagcatag gagataaagc tgtgtccagg tcaagccgca aagggcagcc agtccgaaaa
     6361 tgaggctggt gattatttct aaataaggaa gcataaccca gtgcttttgt tcatgcttag
     6421 agttgtaagt gggctttgcc ataggaaaaa agaggcttga aagatgaagt tgacctatat
     6481 agagcttgac ccaagccttt gcttgctgtt cagaaaacag gttaagtatt agccgaaaga
     6541 ggtttcccac aagaaaacca caatagcaat aaaaaatagt gttcatactt atttatccga
     6601 aaaacaattt aaattcttgc aatattttaa aaaacggtgt acaatgaaac tataaaacga
     6661 gaatgattct aaataagctg ttgatactta tctgaattgg ctcgttatcg tcgaatggag
     6721 ctgacaagag agtgactttt cttgctgcat accattcatg cccttttata tctatcagta
     6781 aggagagttt attatgacaa acacactcgt tgaaaacatt tatgcatcag taactcataa
     6841 tatttctaaa aaagaagcat caaaaaatga aaaaaccaag gctgttttaa atcaagcagt
     6901 agcagatcta tctgtagcag cttcaattgt tcatcaggtt cattggtaca tgcgtggtcc
     6961 tggcttttta tacctgcacc ctaagatgga tgagctatta gaccgcttga acgcgaacct
     7021 agatgagatg agtgagcgct tgattactat tggtggggca ccctactcaa ccctagagga
     7081 gttttcacag cattctaagc tagatgaaac aaagggaagc tatgataagt cagtagctca
     7141 gcatttagct cgtttggtag aggtttacct ttaccttacc agtctttatc aggttggttt
     7201 agacattact gatgaagagg gtgatgctgc ttcaaatgat ttgttcacag cagcaaaggc
     7261 tgacgctgaa aagactattt ggatgctaca ggcagagcgt ggtcaaggtc ctgctatttt
     7321 ctaaagcgtc atacaactga tataacataa aaaaggcaga gcgtggtata gccctgtctt
     7381 tttaacgcct ttaaagtcag ctattagtgc tagtgatgtc aggtctcaca gcttttttat
     7441 gatggatgac caacattttt agaccttgtc accacagcag agcatgtggc atttagtcca
     7501 ccttgggctc acgtcgatgg tcttacttat gatatatcaa ggcttgtgac attaccgttg
     7561 ccttttatct tcagtctgag ctgctggttc ctactgctga tgctgcttga tagtgttata
     7621 gtgattttca gaaatatgga aagcgattgc ataattgtct tgaaatctca tgcgtaattt
     7681 gctaaaatct agttatatga aaacattata cgatgtacag cagctgttaa aaggctttgg
     7741 tattgttatc tacatgggaa agcggcttta tgatattgaa atgatgaaaa tagagctgca
     7801 aaggctatat gatggtggct tgttggataa acaggcttat ttaactgctg agctgatttt
     7861 acgacgtgag catcgattag agctaaaaag agaagggcaa gaaaatgagt caaaaattga
     7921 tagggattga tttgggcgga accacgatta aatttggtat tttaacctca gagggtgacg
     7981 ttcaggaaaa atgggcgatt gagacaaatg ttttagagga cggtaaacat atcgttccag
     8041 atattgtcgc ctcactcaag catcgccttg acctttatgg actgactaag gacgatttta
     8101 tcggtattgg tatgggctca cctggagctg tcaatcgcac agatcatact gttacagggg
     8161 cctttaacct caactggaga ggcacccaag aggtgggatc tgttattgaa agggagctag
     8221 gaattccctt tgctattgat aatgacgcaa atgttgcggc cctcggcgag cgctgggtcg
     8281 gtgcaggtga caataatcct gatgtggtct ttatgacctt aggaacaggt gttggtggtg
     8341 gtatcatcgc tgatgggaac ttgattcatg gtgtggctgg agctggtggt gagattgggc
     8401 acatgatagt agagccgctt aagggctttg cttgcacctg tggctcacag ggctgcctgg
     8461 agacagtggc ctctgctaca ggtgttgtta aggttgctcg tcttttagca gaagcctacg
     8521 aaggagattc aagcattaag gcagcgattg ataatggaga ggctgtctca agcaaggaca
     8581 tttttgttgc agcggaggct ggtgatgcct ttgccaactc tgttgttgaa aaggtcagtt
     8641 attatctagg actggcagcg gctaatatct caaatatttt gaaccctgat tcggtcgtta
     8701 ttggcggtgg tgtatctgct gcgggtgagt ttttacgttc acgtgttgaa aagtacttta
     8761 tgacctttac ctttccgcag gttagacagt ccactaaaat caaaatagca gagcttggta
     8821 atgatgctgg tattattggt gcagctagcc ttgcaagaca atttatcaca gaataggagt
     8881 taatgatgtc accacttaca atgattggct gggtattgct tgcgggagtg attgcctatt
     8941 acctttggaa ttatgtttcc tatagaagaa tggcaaagca ggttgataat gataccttta
     9001 aggagctgat gcgtcagggg caagtgattg acctgcgcga tccagcttcc tttagggcaa
     9061 ggcatatcct aggcgctaga aattttcctg cccagcagtt tactacctct attaaggctt
     9121 tgagaaagga caagccaatc ttgctttatg aaaatgtaag acctcaatat cgggtcaaag
     9181 cagtcaaaac attacgtaag gctggctata cggaccttta tgtcctaaaa gcgggactag
     9241 attattggaa tggtaaggtt aaatagcctt atagtccttt ttgctgagct aacgtttgct
     9301 gctatgtgtc ggaacgttgc aagcagcagc ttatctaagc ttgtcatgct agtttcacag
     9361 cccaaagtgg ctggccgtat aaacgcagct gcttttagat gccggtagga gcttttgtca
     9421 gcttctttag ggattgtttt aagtgatgta gagaggccgt tctgagagaa agccttgtag
     9481 ttagaaaaag agatgagaaa gctaaggctc ttgctgctgt tgtaagagtt agctttcttt
     9541 ttcttttttg tgtggcgcat ttaagggctt gaaaacattt acaattccct cagatcggtt
     9601 ttttaaaaaa atttgtgtta tactgtttta gttaaaacta tttatgctac aagaggaaaa
     9661 aatgacaaaa tttagagaag atattcgtaa cgttgctatt attgcccacg ttgaccatgg
     9721 gaaaacaacg ctcgttgatg aattactaaa gcaatcccat acactagatg agcgcaaaga
     9781 gcttcaagaa cgtgcgatgg attcaaatga ccttgaaaaa gagcgtggta ttaccattct
     9841 tgctaaaaat accgcagtag cttataacga tgttcgtatt aatatcatgg atactcctgg
     9901 gcacgctgac tttggaggcg aggttgagcg tatcatgaaa atggttgatg gtgttgtcct
     9961 tgttgttgac gcttacgagg gaaccatgcc tcaaacacgc tttgtgctga agaaggcctt
    10021 agaacaaaat ttaaccccaa tcgttgtggt taataagatt gataagccat cagctcgtcc
    10081 agctgaggtt gttgatgagg ttcttgagct tttcattgag cttggtgcag acgatgatca
    10141 gctggagttc cctgttgttt acgcttcggc gatcaatggc acatcttcgt tgtcagatga
    10201 tcctgctgat caggaaaaaa caatggctcc gatttttgat accattatcg atcatattcc
    10261 agcacctgtt gataactcag ctgagcccct tcaattccag gtgtcacttc ttgattacaa
    10321 tgattttgta ggtcgtattg ggatcggtcg tgtctttcgt gggactgtta aggttggaga
    10381 tcaggtgacg ctttcaaagc ttgatggcac cactaaaaat ttccgcgtta ctaagctgtt
    10441 tggcttcttc gggcttgagc gcaaggagat tcaagaggcc aaggctggtg acttgattgc
    10501 agtttctggt atggaggaca ttttcgttgg tgagacgatt acaccaacgg attgtgtgga
    10561 ggctttgcct gttcttcgca ttgatgagcc gacacttcaa atgaccttct tggttaacaa
    10621 ctctcccttt gctggtcgtg aaggcaaatg ggtaacctct cgtaaggttg aggagcgttt
    10681 gcttgtggag cttcaaacag atgtgtccct tcgtgttgag ccaacagaat caccagataa
    10741 atggattgtg tcaggtcgtg gtgagctgca tctatctatt ttaattgaga ccatgcgtcg
    10801 tgagggctat gagcttcagg tatcgcgtcc agaggttatc attaaggaaa ttgatggtgt
    10861 caagtgtgag ccttttgaac gtgtacagat tgacacacca gaggaatatc aaggtgctat
    10921 tatccaatcc ttgtcagaac gtaaggggga tatgcttgat atgcagatgg ttggtaatgg
    10981 tcaaacgcgt cttatttttc tcattcctgc ccgcggcttg attggttatt cgactgaatt
    11041 tttatcaatg acacgtggct atggtatcat gaatcatacc tttgatcagt atctgccagt
    11101 ggttgctggt gagattggtg gacgccatcg tggagcgctg gtttcgattg aaaacggtaa
    11161 ggcaacaacc tactcaatca tgcgtattga agagcgcgga acaatctttg ttaacccagg
    11221 aactgaggtt tatgagggca tgattgttgg tgaaaattct cgtgacaatg accttggggt
    11281 taatatcaca actgctaagc agatgaccaa cgttcgttca gcaacaaagg atcagacagc
    11341 tgttatcaaa acaccacgta ttctaaccct tgaggaatct cttgaattct tgaatgatga
    11401 cgaatacatg gaggtaacgc cagaatcaat ccgcttgcgc aagcaaattt tgaacaaagc
    11461 agcgcgtgat aaagctaata aaaagaaaaa atcagcagaa taaaggctgg ttggtctgag
    11521 catcacactc ccttgccgct ttaactagta agctaggttg gcagaggatt gaaaggagct
    11581 ttctgtgttt tatcttatta ttgcagcctt gattacctct tattacctgt ttatggcacc
    11641 aaagagcgtc cgtaacacac taggtatgat tggtttggtt ggtttggttg ccctattgat
    11701 tgtgctagct ggcttaagtt ttatcaaaat catgcaaacg cccaaggaaa ttttcgttgg
    11761 tctagccatg atagtattgg gctactatgc cctaagggac attcaaaaaa tccctaaaaa
    11821 accaaagagt aaacattagc atcaagcatt gagtcaaatc ttaatagggt ttgacttttt
    11881 ctgtctttgt actggcctta tgcgctgcta tctgtaaaat cttgaaaaag cagttaaata
    11941 agggtaaaat agtagtcaaa tagacataga tagtgtggat aaaaatgaag acaataacgg
    12001 aattccaaaa taaaaaggta ttgattcttg gcctggccaa atcgggcgaa gcagcagcta
    12061 ggcttttagc ccggttggga gctattgtga cagttaatga tagcaagccc tttgaggaaa
    12121 atcccgcagc acaggctctt cttgaggagg gcataagggt tatttgtggt agccacccct
    12181 tggagctgtt agatgaagac ttttattgta tggttaaaaa cccagggatt cgctatgaca
    12241 acccgatggt ggtacgcgcc ttagataagg ctatttctat tctaacagag gttgagctgg
    12301 cttatttggt atctgaagca cctatcattg gtattacggg ctcaaatggt aaaaccacta
    12361 caaccacaat gattgctgat gtgctaaatg ctgggaacca ttcagctctt ttggctggga
    12421 atatcggctt tcctgcttca gaggtggctc aagctgctac agcaaaggat atactggtca
    12481 tggaattgtc ttcctttcag ctgctgggga ctgagcagtt tcagccacat attgcagtca
    12541 ttactaacct agtgcctact catcttgatt atcatgggag ttttgaggac tatatagcgg
    12601 ccaagtggcg cattcaacat cgaatgaccg ataaggatta ccttgtgtta aatgctgatc
    12661 aagagctggt aaaatcattg gctcaaaaga ctaaagcaag tcctgtcttt ttttctacca
    12721 aagaaaaagt tgatggtgct tatttggcag atgggtatct ttatttcaaa gaggagaggc
    12781 tgatgtcagc agctgagctt ggtgttcctg gaaggcataa cattgaaaat gctcttgcca
    12841 ccattgctgt tgcaaagcta agaggcattt ctaatcaagt gatatcaagg actttgtctc
    12901 actttagggg ggtgaagcac cgccttcagt tagttggtac attgaatcaa gtgaccttct
    12961 acaatgacag caagtcaacc aatatcttgg cttgtcaaaa agccttgtcg ggctttgata
    13021 atagcaaggt tatcctgatt gctggtggct tggatcgtgg caatgaattt gatgagctgg
    13081 tgccagacct cgttggtctt aaaaagatga ttcttttagg ggaatccgca gagcgtatga
    13141 agcgagctgc agacaaggca ggagtgtcct atcttgatgc caaagatgtt gcagctgcca
    13201 ctaaaatagc ctttgagcag gcaaaggctg gtgatattat cttgctgagc ccagccaatg
    13261 ctagctggga tatgtatcca agctttgaaa gccgcggcga cgagttttta gcagcctatg
    13321 acgcgttaaa aggagaggct caatgaccaa gaaaatcatt tttaccggtg gtggaacagc
    13381 tggtcatgtc actttaaacc ttatcctcat accgaagttt atcaaagatg gctgggaggt
    13441 tcactatatt ggtgatgaca aaggcattga gcatcaggag atcaaaaagt caggtcttga
    13501 tgtcaccttt catgctattg caactggaaa attaaggcgt tatttctctt ggcaaaacct
    13561 gcttgatatc ttcaaggtag gctttggtgt catgcaatca ctttttatca tagctagact
    13621 aaggcctaag gctctctttt caaagggagg ctttgtgtcg gttcctcctg tgattgctgc
    13681 aaggctttta ggggtgccgg cctttattca tgagtcggat ctttctatgg gcttggctaa
    13741 taggattgct tatcggtttg caacaacgat gtatacaacc tttgagcaag agcagacact
    13801 ggcaaagctc aagcatgttg gagcggttac caaggtgaca ggtcctggga gtcgatcggt
    13861 gacttctaag cagcttgaag ctgttttgga gtattttgat cctaatttaa aaacactttt
    13921 gtttattgga ggctccgcag gggctagggt gtttaaccgc tttatcactg accatcctga
    13981 gctaaaggaa gactttaata tcatcaatat ctctggcgat cctagcctaa atgagcttag
    14041 ttggcatctt taccgcgtgg attatgtgac tgatctgtat caaccgctca tggaaatggc
    14101 tgatctggta gtgactcgcg gaggctctaa cacacttttt gaattattag cgatgagaaa
    14161 gctccagctt attatcccac ttggcaaaga ggccagtcga ggtgatcagc ttgagaatgc
    14221 tcattatttt acaacaaggg gctatgctga gcaattattg gagcaggaat tgaccctgcc
    14281 tcattttcaa gagaaagtga gagaagtctt tgctaagcaa tcggactatt tatctgcaat
    14341 gaagagctct agcgagctcc aatcaccaga aagcttttac cagcttttaa gtgccgacat
    14401 tagctccgcg acaaaggaaa attaaatggc agataagaca aaacattcag aagaaaaagc
    14461 cgctttgacc gaatggcaaa agcgtaatat tgaatttctc aacaagaagc agcagcaggc
    14521 tgagaaagac aaaaaactaa aagaaaaatt attaaatgag aaaatagcgc aagctcaggg
    14581 agaggcagct tcaaaggctg accaagaaga tacagatgaa gctgaggaga aaactgaggt
    14641 aagccaagcg ggtactgatg agggtgagcc gctgccagaa gcatcagagc aggaagtccc
    14701 ctccccaaaa gacaagccat taaaagtccc caaagaaaaa agtccaaagc agcaggcact
    14761 tcaaaagggc tggcctgtat tgctggtgtc gtttgtggtt ttgtgcctgt cgatttttat
    14821 gatcacaccc tatagtaagg tcaaggattt ctccgtcaag ggcaataaaa aaacaagcgt
    14881 tgaggactta gttagagaca gtgggatcaa gtcatctgat tactggatta ctctattagc
    14941 ctctccgggt tcttatgaaa atgcggtttt aaaagccaat ccctgggtga aaaaggtggc
    15001 tttgcgttac ggctttccca atcatttccg ctttgatgtg acagagtttg atattattgc
    15061 ctacgctcag gtagctgaag ggtttcaact gatcctagaa aatggcaagc gagttgctgc
    15121 tgtcaagcag gctgctttgc ctaaatcctt tttgatttta aatcttgagc atgaaaaaga
    15181 gattcaagat gtcattaatc gcttgaccaa aatcccaagt gacctagtca aggctatcaa
    15241 atcagtgtca tcggccaatt cacagacaac taaggatttg ctgcttcttg aaatgcacga
    15301 tggcaacctt atcagggtac ctcggtcaca gcttgagcta aagctgcctt attaccaaaa
    15361 aatcaagaag aatcttgata ctgctagcat tgttgatatg gaggttggta tctatacgac
    15421 cactgctgaa attgaaaaca tgcctgaggt gccagcgtct gctcaagctt ctcaggcaga
    15481 taagcctgct gaggcttcac cagagcaggg tgaagagcag gccacacagg agcagcctag
    15541 ccctgaaaca cctgctaatc ctgaggccac aaatccctca gtcgcccagc ctactgagca
    15601 ggcaaatcaa cagtaatcgt ttagggtaag agaagggggc aaaaaagcat ttaaggctct
    15661 taaattaggc ccttgttgaa cggcaaaaaa acattaagtt tatataacaa aaaacgtaaa
    15721 atggtaacat tttacgtttt tttatgatat aatattccct gaataattct gctttttagc
    15781 agtgtttttg aatagtaaaa gtttggaaag taagtgaggt cgagtgaatg gctagaaatg
    15841 gcttttttac tggtttggac attggaacaa gctcgataaa ggttttggta gcagagttta
    15901 tctctggcga gatgaatgtt attggtgtga gcaatgttcc gagtactggc gtaaaagatg
    15961 gcataatcat tgatatagag gcagcagccg ctgctattaa aactgcagta gaacaagctg
    16021 aagaaaaagc aggaatgaca attgaaaggg tcaatgttgg gctgccagca aacctccttc
    16081 aaattgagcc gacacaaggc atgattcctg ttcctagcga atcaaaagaa atcaaagatg
    16141 aagacgttga tagcgttgtt aagtcagcac taactaagag cattactcca gagcgagagg
    16201 tgatttcctt agtccctgaa gagtttattg tagacggctt tcagggcatt cgagatcctc
    16261 gtggcatgat ggggatcagg cttgaaatgc gcggtctgat ttacactgga ccaagcacaa
    16321 tcctgcataa cttaagaaag acagttgagc gtgctgggat taaggttgaa aacatcatca
    16381 tttctccttt ggcaatggct aaggcggtgt taaatgaagg tgaacgtgaa tttggtgcta
    16441 cggtcattga catgggtgga ggacaaacca ccgttgcctc aatgcgagca caggaattgc
    16501 agtacaccaa tatctatgca gagggtggcg agtatatcac aaaggatatc tctaaggttc
    16561 ttaaaacgtc aatgtcaatt gcagaggcct tgaagtacaa ttttgggcag gctgatatgg
    16621 cagaggcaag cttgactgac actgttaagg ttgatgttgt tggcagtgat gagccagttg
    16681 aggtaacaga gcgttactta tcagagatta tctcggctcg tgttcgccat attctagatc
    16741 gtgttaagca ggatttagaa agaggacgcc tgcttgattt acctggtggc attgtgctga
    16801 taggtggcgg cgccattatg ccgggcgtgg ttgaggttgc tcaagagatt tttggaacca
    16861 atgttaagct tcatattcca aatcaggttg gtattcgtaa cccaatgttt gccaatgtca
    16921 ttagcttggt cgagtacgtt ggtatgatgt cagaggtgga cgttttagcg caaaatgctg
    16981 tatcaggcga ggaattgcta agacgtaagc cgatcgactt tactggccaa gaagcttact
    17041 tgccagacta caatgagact aggggatttg aaccggctcc taattatgag cagcaagtgc
    17101 cccaagcaga ctacgagcct caagaacccg ctgaaccaaa gcaaaagatt tcagagcgtg
    17161 ttcgtggcat ttttggaagt atgtttgatt aaaagtaata aagtgaggaa ataaaatggc
    17221 attttcattt gatacggcat ccattcaagg tgcaatcatt aaggtaatcg gtgttggtgg
    17281 aggtggcgga aacgctatta accgcatgat tgatgagggg gttgcaggtg ttgagtttat
    17341 cgctgcaaac actgatattc aggcattaag ctcatcaaaa gcagaaacag ttgttcagct
    17401 tggtcctaaa ttaactcgtg gtcttggtgc tggaggtcag ccagaggttg gtcgtaaggc
    17461 agcagaggaa agcgaagagg ttctcacaga agctttgact ggcgctgata tggtctttat
    17521 cactgctggt atgggtggag gctctggaac aggagcagct ccagtgattg ctcgtatcgc
    17581 taagagccta ggagccttga ctgtggcagt tgtaacacgt ccatttggct ttgaaggcaa
    17641 caaacgcagt aattttgcca ttgaggggat tcaggagcta agagagcagg ttgatacctt
    17701 attgatcatc tcaaataata acctgcttga aattgttgac aaaaagacac cattgcttga
    17761 agcgcttagc gaagcagaca atgttttgcg tcagggtgta caagggatta ctgatctgat
    17821 tacaagccct ggcttgatta atcttgactt tgccgatgtt aagactgtga tggcaaataa
    17881 aggcaatgca cttatgggga tcggtattgg ttctggtgag gaacgtattg tagaggcagc
    17941 tcgtaaggct atctactcac cattacttga aacaacaatt gacggtgctg aagatgttat
    18001 cgttaacgtg acaggtggac ttgatatgac cctcacagag gctgaggagg catctgaaat
    18061 tgttggtcag gcagcaggtc aaggcgttaa catctggcta ggaacatcga ttgatgactc
    18121 tatgagagac gaaattcgcg taacagttgt tgcaacaggt gttcgtcagg ataaggcgga
    18181 gcaagcctca ggatttcgtc agccacgcac ctacactcag tctaacgctc agcaggctgc
    18241 tggagcacaa tatgcttcag agcaggtgag acagactgcg cagccaagct ttgatcgtcg
    18301 ttcatcaagc tttgattttg atatgggtga aacacgtgag atgcctaagt ctcagcaagc
    18361 tatgccagct catggccaca atcataatca gggctcagct tttggaaatt gggacttacg
    18421 tcgagacaat attgctcgtc cagcagaagg tgagcttgac aatcaattga acatgtcaac
    18481 cttctcatca aatgatgaca ttgatgatga attagaaaca ccaccatttt tcaaaaatcg
    18541 ttaatgatgg atttacaaaa aaataaggat attgtttttg aaaatattcg cttagccact
    18601 caggcagcca accggcctga aaacagtgtg tcagttatcg ctgtcacaaa atatgtggac
    18661 aaggcagttg caggtcagct gattgatatg gggattgagc atatcgctga gaaccgtatt
    18721 gataagtttc tagataaata tgaagccttg aaagataggc aagttacttg gcattttatc
    18781 ggtactttac agcgtcgaaa ggtaaaggaa gtgattaata aggttgatta ttttcatgcc
    18841 ttagattcag taaaactggc tttagaaatt gaaaagagag ctgaccaccc tgtgaagtgt
    18901 tttctacaag ttaatatttc tgaagaagaa agcaagcatg gttttaagat tgctgagctt
    18961 gatgctgcta ttgaggaaat cagcaagatg gaaaagcttc atcttgtcgg tatcatgaca
    19021 atggcaccta ttgatgccag tcagcaagag cttagaagca ttttccaaaa agcaaatcaa
    19081 ttaagaaaaa acttgcagtc aaaaaagaga aagaatatgc cgtttacaga attgagtatg
    19141 ggcatgagta acgattatcc aattgctatt caagaaggct caacctttgt tcgtattgga
    19201 acatctttct ttcactaaat ggagaataag atggcaatta aagacgcatt taataagatg
    19261 atttcttatt ttgatactga tggggtcagt gaagtagaag aggagctatc ctctaaaaag
    19321 caagaagagc ctgtgactaa atcacaacag accagcagac ctaatcagca gcaacaagca
    19381 gctagagcga gtcagcccca gcagcctaag caggctagac ctcagatgca agctcagcaa
    19441 agaccacaat cacaatcaag agctgcctat gctgagcgac catatcaagg tcaaagtcaa
    19501 gcacgtgttt ctcatgacta caatgacaga agggcgacgt cagccccgtc tgcttctagt
    19561 cgtcgtgagc aatatcagca tgctgctcat caagagcaaa caactattgc cttgaagtat
    19621 cctcgtaagt atgaggacgc ccaagaaatt gttgatcttt tgattgttaa tgagtgtgtg
    19681 ctgatcgatt ttcaatacat gctagatgct caggcaaggc gttgcctaga ttttattgac
    19741 ggtgctagta aggtattgta tggtactctg caaagggttg gttcttccat gtatctgttg
    19801 accccatcaa atgtatctgt taatattgaa gagatgaata tcccaaataa tggccaagat
    19861 attggttttg attttgatat gaagagacgc tagtgtgatg atttttatac tgttgatact
    19921 tctaaagcta attaaggttt attcctattt gctgctagtc tatgccttac tgtcttggtt
    19981 tcctggagcc tacgactctt ggcttggcag gctggtcagc gatatagtag agcctatctt
    20041 aaaacccttt agatcattga acctacagtt tgcgggcttg gactttacta tttacctagt
    20101 gatgattggt ctaaatgttt taagtgagat cttgataaga gtgttgatct catgactgtt
    20161 caaacaatgc tttatcagca ttttcagcct gatgaacacc catttattga aagaatgctt
    20221 gacttgatcg ctcgtgttga ggctaattat ttattagagg ttactgattt tttaaatccg
    20281 cgagaggtca cgattttaaa aggcttagtc gcagcaacca atctgcagtg ctttagctct
    20341 actgattatt atcctagtga atatggtcgt gtgattgttg ctcctgacta ttattgtcta
    20401 gataaggcag attttgactt ggctttgatt gaggtgacct ataatgctaa gtttaatcag
    20461 ctgacacatg cacagatttt aggcacctta attaatgaat tgggaatcaa aagagcctta
    20521 cttggcgata tttttgttga gataggtcat gctcaggtca tgattaatcg acagctgtta
    20581 agctattgtt taggaacgat tgctaaaata gcaaaagcta gggtcaagct caaagaaatt
    20641 gatcttgatc agctgttaaa tctgacagct aatcagcagg ttctgactga tataatggta
    20701 tctagtctac gcgttgatcg cttgattgct accgtattaa agcaatctag aaatcaggcg
    20761 ataaggcttg ttgaagcagg caaggtcaag gttaactatc agcttgtcac taaagcctct
    20821 cagcctgtag ctgttggtga tttaatcagc attcgtggct acggtaggtt tagcatacta
    20881 acagacaatg gcttcacaaa aaatgggaaa tataagctaa cacttagcaa aatgatgcgt
    20941 aaataaggag atataatggc acttacagca ctagaaatta aagataaaac gtttaagaca
    21001 aagtttcgtg gctacagtga agaggaagta aatgaatttc ttgagattgt tgtagacgat
    21061 tatgaggctt tggttcgcaa aaatcgtgat aatgaagcta agataagaga gcttgaagaa
    21121 aagctgtctt actttgatga gatgaaggaa tcattgagtc aatctgttat cctagcccag
    21181 gaaacagctg aaaaagtgaa atcctcagca aatgctgaag caaccaattt ggtcagcaag
    21241 gcaacctatg atgctcagca tttacttgat gagtcaaaag caaaggctaa ccaactgttg
    21301 cgcgacgcaa cagatgaagc aaagcgcgtt gctattgaga cagaggaatt aaagcgccag
    21361 acacgcgttt tccatcagcg cttggtttca gctattgagt cacagctaag cttatccaat
    21421 tcgcctgagt gggacgaatt gttgcagcca acagctgtct accttcaaaa ctctgatgca
    21481 gcctttaaag aggtggttaa aactgtcctt aatgaagata ttcctgaggc tgatgacagc
    21541 aattcctttg atgcaacacg tcagtttaca ccagaggagc tagaggagct gcagcgtcgt
    21601 gttgaagaaa gcaataagga gctagaagcc tatcaggtgc agcgagaaga gcaagctagc
    21661 gagcctgaag tgaacctaag cgagacacag acctttaaat tgaatattta atcataagaa
    21721 aaacaggatt gaatgcccaa aatcacagca agtaggagat gatgagagtc ctatattccc
    21781 tgagcatgac aattatcatt ttcttcaatc atcactgaat gacagtaagt gacgagggag
    21841 gctcacctta cgagcaaaga gggaacagca aaagggattt tactgttctg aattaaggtg
    21901 gtaccacgag ctttcgtcct ttttgagacg gggctttttt tgtaattctg ataagatatt
    21961 gactaaaagg agtttgacaa gatgaaatta aaagaaacac ttaacttagg caaaacggcc
    22021 tttccaatgc gtgccggtct acccaacaag gagccacaat ggcaaaaggc ttgggacgag
    22081 gctgagattt acaaaaaacg tcaagcctta aatgaaggca agcctgcctt tcacctgcac
    22141 gatgggcctc cctatgcaaa tggtaatatc catgtcggac atgcgctgaa taaaatttca
    22201 aaagacatta ttgtacgtgc caaatctatg tcaggctatc aagcgccttt tgttccaggt
    22261 tgggatactc atggccttcc tattgagcag gtcttggcta agcagggggt taagcgtaaa
    22321 gagatggatc tggctgacta tcttgacatg tgtcgtcagt acgcgttaag tcaggttgat
    22381 aagcaaagag acgactttaa gcgtctcggt gtatctgctg attgggacaa tccttatgtt
    22441 accttagatc caagctttga agccgatcaa attcgtgtct ttggtgcgat ggctgataag
    22501 ggctacattt atcgtggggc aaagcctgtg tattggtcat ggtcctctga atctgctctt
    22561 gctgaggcag aaatcgaata ccatgatatt gattctacat cgctttacta tgctaatagg
    22621 gttaaagatg gtaagggaat ccttgatact gacacctatg ttgtggtttg gacgaccaca
    22681 ccatttacgg taacagcttc tcgtggtcta acagttggac ctgatatgga ttatgtggtt
    22741 gttagacctg caggttcaga ccgtaactat gtggtggcag aaggactgct agacagtctg
    22801 gctgctaagt ttgcttggga atcatttgag attttggcca atcataaggg ctctgacttg
    22861 gaatacattg taaccgagca cccttgggac agtgaggttg atgagctagt cattcttggc
    22921 gatcatgtga cgctagattc aggtacaggt atcgttcata cagcacctgg ctttggtgaa
    22981 gatgactaca acgttggtat gacatatgga cttgaggttg cagttacagt tgatgagcgt
    23041 ggtttgatga tggaaaatgc aggtcctgat tttcatggtc aattttatgg caaggtaact
    23101 ccgattgtta ttgaaaagct tggagaccta ttgcttgctc aagaagtgat caaccactcc
    23161 tatccatttg attggcgcac gaaaaaacca attatttggc gggctgttcc tcagtggttt
    23221 gcttctgtgt ctgacttccg tcaagagatt ctagatgaga ttgacaaaac aacattccac
    23281 ccgacatggg gaaagacacg actctacaat atgattcgtg atcgtggcga ttgggtgatc
    23341 tctcgtcagc gtgcttgggg tgttccactg cctattttct atgcagagga cggcacagcc
    23401 attatgacta aggaggtaac tgatcacgtc gcagatctgt tccaagagca tgggtccatt
    23461 atttggtggc aaaaagaggc taaggagctt ttacctgaag gcttcacaca cccaggctct
    23521 ccaaatgggg tatttaccaa agagacagat atcatggacg tctggtttga ttcagggtct
    23581 tcttggaatg gtgtgatgaa tgctcgtgat catcttgctt atccagctga cctctacctt
    23641 gagggctccg atcaatatcg tggttggttc aactcatcac tgattacctc agttgcggtt
    23701 aatggtcatg caccgtataa ggctatccta tcacagggct ttgtccttga tggtaagggt
    23761 gaaaaaatgt ctaaatctaa aggaaatatc atttcaccta atgatgttgc aaagcaatat
    23821 ggtgctgata ttctccgtct ctgggtagct tctgttgata cagataatga tgtgcgtgtg
    23881 tcaatggata tcctaggaca ggtctctgaa acctatcgta aaatccgtaa cacgcttcgc
    23941 ttcttgcttg ctaatacatc agacttcaat ccacatacag ataaggtggc ttatgctgag
    24001 cttgctgctg ttgataagta catgaccatc aagtttaaca agctagtagg agctatcaat
    24061 actgcctatg agcgttatga cttcatgacg atttacaagg ctgtggttaa ctttgtgacg
    24121 gttgacttat ctgctttcta ccttgatttt gccaaagatg tggtctacat tgaggctgct
    24181 aacagcctgg cacgtcgtcg tatgcagact gtcttttatg atattttggt taatatcact
    24241 aagctattga ctccgatcct tccacatacg gcagaggaaa tctggtcata tttagagcat
    24301 gagccagaag actttgtaca gctatcagag ctgccacagg ctcagacttt tgataatcaa
    24361 gatactatcc tagaggaatg ggaagccttt atgacgcttc gggcacaggc gcaaaaggct
    24421 ttggaggaag cacgtcatga caagattatt ggtaagtcct tagaagctca tctgacaatt
    24481 tatgcaagtc cagaggttaa gacactgttg acagctctag atagcgatat tgcactgcta
    24541 ttgattgtct ctcagctaac cattagtgag gagccagctc ctgagaatgc tgtcagcttt
    24601 gatgatgttg cctttacggt agctcgtgcg caaggagagg tttgtgagcg ttcacgtcgt
    24661 atcgatccaa cgaccagaat gcggtcttat aatgcctttg tttgtgacca cagtgcgaaa
    24721 attatcgaag aaaacttccc agaagcagta gcagaaggct ttgactcagc tgctaattaa
    24781 gcaactaaca gctctgttcc cgagttaaat aagcattggc gtgcttttgc caatccagca
    24841 gcaaggtgct agtcggtctg ggcgtacctg ccttactagg gactctttgt gtgggagctg
    24901 ataagtgacc tgccttgagc ttggcaggtc taggcttctt tataggttca cgatttacga
    24961 ttgactgggc ttagagaagg gctagtcctg ctaggcggca ttggatatga actgagtagt
    25021 catcatagct ataaaaaaac aagcgcagac tcacgtcagc ttaatcgtga gcggcgcttg
    25081 ttttttcttg gttggggggt gaaggcgagg agctattaaa gctaatatta agcgatcaaa
    25141 aaagcctaga ccactagtca tgttgtctaa gcttcagctg ttagagagga gctttctgag
    25201 tggaaggtag cctatgctga taggtgctgc cttagccttt tagcagtagt attaaggcta
    25261 gacagacgtc tggaaggaaa tttcaatcaa attattggtg tgcagggttt ttgagtgacc
    25321 tggaatcaca atagattggt caatcttacg ctttaagaaa aattcgcgaa tcacttcaag
    25381 ctcgtcctct ttgatggcac gatatttatt tgaaatgagt agctcataat gcttgggtgc
    25441 ttgcgtaaag atgacgtcag tgttaccagc tgagtaaact tcaacgaggt gagcatctgt
    25501 attttgcagc tgatttctga caagctcggg gtgactgctg gtggtattaa taagtctcat
    25561 aaatcttctc ctgactattt ttacttttat tatagcacta tttttaaatt gattacggat
    25621 tttaatggtg ctttttctgc cattcttcga cgccccatct gtggctatca cgctttaaga
    25681 ctgttatggc gtccgcaata ggaagaaacc aagccagatg gttaaagtct tccaagggct
    25741 ttgagatagc ttggaatgat gtcacctcgt acaggtaggc aggattatag tagtaggtat
    25801 cgcggtgacg agaatagaag tattcgtctg cttgaccata ataataacca atatcagcag
    25861 caaatcccag ctcctcaact agctcacgct ccagtgcctg tagctggctt tcaccagcct
    25921 ctatttctcc tcctggcaaa aaccaagcac catttggagc ctgcactagg ataatctctg
    25981 ttttagccga gttaggaatc actgcataga caccgtaacg tgcggtgtaa tgctggtcat
    26041 ctatcttatc accaaatatt ggaacggtca tatcgcttct cctttgtttt attatactaa
    26101 atttttggtc attattctca taaaactgta gatttatcaa aaatgtttca taaaaaaatg
    26161 ctcgtcaaaa agagagaaaa tgctgtctgc ttttctctct gcttttctct ctgctttttg
    26221 gtatgccctg ttagtccgcc tgcttcgcct gagatttgac tacaggcttg attataatgt
    26281 gtccattaga ggtcaagaca gctcgcatgt ctttttctgc tgggtgctca aggtagaagt
    26341 cagtaatggc gtcctcaatg tagtcctgaa tggtgcggcg caatggtcgt gctcccatct
    26401 taggatcata gcctagctca acgagctttt ctttgacctt ttgggtgaca tcaaggcgaa
    26461 tgttattgtg agcaaggcgg tggttaacat catcgagcat taaatgaacg atatgtaaaa
    26521 gattgtcctt gcttagtggc tgaaactcaa taatgccatc aaagcgattc atgaactcgg
    26581 ggctaaagaa atgactgagc tctcctaaaa cagagtttgt ccgcccttct ctagcagcgc
    26641 caaagcctac tgaggcctct gttttgccag tgccagcatt tgatgtcatg atgataatag
    26701 tgtccttaaa gctaacggta cgtccttgtc cgtcggttaa tcgtccgtca tctaggacct
    26761 gtaaaaacat gtgcatgaca tcagggtgag ccttttcgat ctcatctaac aaaatgagcg
    26821 agtaagggtt gcggcgcacc tgctctgtta actgacctgc ctcctcatag ccgacgtagc
    26881 cgggaggggc accgacaagc ttagccacag cgtgcttttc catgtattca gacatgtcaa
    26941 agcgaatcat gttatcagca gagccaaaaa gctcaatggc taattgcttg gaaagctctg
    27001 ttttaccgac accagttggg ccaacaaaga ggaaggagcc gataggacga tttggggctc
    27061 ccagtccaac acgattacga cggatagctt ttgcaatttt atcaacagca tcgtcttgac
    27121 cgataacatg ctttttgaga tcggcggcca gattgactag ctgtgattgt tccttttcct
    27181 ttaaatcacc aactggaata ttggtttttt gctcaacgat tgcttcgatg gtcttgtcag
    27241 tgatgattgg aatatcctgc tcatctagct tttgagcctg catttcttta tatttggcga
    27301 tttgatcgcg gaaataggct gctcgctcat aatcctcatc acgtgtggct tgtgtcttga
    27361 ggttttcagc ctcaatcaaa cgcttatcaa tgtctttggg gtcaacaaag ttaagggtta
    27421 ggttcatctt tgagccggct tcatctagca ggtcaatggc cttatcaggc aagaagcggt
    27481 cttgaatata gcggttggag aggttagcag ctgcttcaat agccgactgg ctatatttga
    27541 catggtgata gtcctcatat ttgggttgga ttccttttag gatagtgatt gtttcttcaa
    27601 ccgaaggctc gtccacctta accggctgca tgcgtcgctc aagggctgcg tccttttcga
    27661 tgatgcgata ttcattgaga gtggtcgctc ccactaattg aagctcacca cgagcaagtg
    27721 ctggctttaa aatatttcct gcgtccatgc tgccgtcacc aactgcacca gctcccacaa
    27781 tttcatggat ttcatcaata aatagaatca cgtcatggcg cttgcggatt tcctccatga
    27841 gcttttgcat gcgctcttca aattggccac gaatacctgt cccctgaacg aggctaacca
    27901 catcaaggcg aatcacctgc ttactctgta gcttttgtgg cacatcgcca tcaacgattt
    27961 tttgagcaag gccttcaacg acagcagtct taccaacacc tggttctccg attaggacag
    28021 ggttattttt ggtacgacgg ttgagaatct cgatcacgcg gataatctca tcgtcacgtc
    28081 cgatgacagg atcaatatca ccacgcttag ccatttcagt gatattaatg ccgaattcct
    28141 caagcaaacc tttgttagcc tcttgtgctg gctgtgtgtg attgggacgg tagccattgt
    28201 gacctccgcc attatggccg cctgattggg taggtggtgt attgggcaat tgaccgaagg
    28261 ctctaaaatt gttcaggtca ccaaaaaagt catcaaagaa agggttttga gaaggctgct
    28321 gcgccttttg gttgccatta tagcctccta agataggatt tttagggtct gttttcatga
    28381 tttggtagca attttgacag aggtcaatct gcctttgctt tccgttaatg cttgtataaa
    28441 gatgaatggt tgattcgttt aaattacagt tttgacaaag catatcatac ctccaagggg
    28501 ttatctaaaa agtcaaggtc atttagtcaa aaatggtcaa actttatagt catattatag
    28561 caccttaggc ttggaaatca agtaaaaagc ttcattatta gcactttcag gtatagagtg
    28621 ataatctcta taaatcttgc tgctcattgg ttcaaaaaag tcgtcaaagg ggataaaata
    28681 aagagaaaat ggctactttt cttgtttgtt ttcgatgatt tatgttaaaa tatataggga
    28741 caataaacga ataggagaaa cgaaatggaa tcacatttag tgagaatcat caaccgtctg
    28801 gagctgatgg taacagatgg cggtaattta aagagaaact ttgagcgaga tggtgttgtt
    28861 gttgcagagg ttgcatttgt caacgatcct gaaaatggtc cagtctttat tttacgtgat
    28921 attgaagcgc gtgagtcata ttcatttgat agcatcgatt tgattgcgat ggaaatttac
    28981 gatttgttat attaagctat tgatgatgac atgggcttgc tgggaggcag gtcagacaga
    29041 ggacaagctg gtgatttact ggtttgtttt tattatccct taaagcctca agacagctcc
    29101 aggaaaggcc tttctcctat ggtctttcta gccggtaggg cttgatagtg attaatagtg
    29161 atctgctcta gcacggtctt gagcttttac tgtcagaggc ttgtgacctt agccactcgc
    29221 agtaaagggt actggcccag taagcaaggt aggctaagta tcaatgtgaa gttctaacct
    29281 tgatcttagt gaaatatttt tgaggtgaat taagatgtta aaagtcctta gaatgctcat
    29341 ttctaagggt tttgttgtgt ctagctgttg gtgtttgaaa gagcggtggt atgataaaga
    29401 gaggtcagaa aagacctctc tgatgtttgt gattagctgt tagctattgc cataggggaa
    29461 agacacaata gctagcttag cttttctttt tctttaggtt taggacgcct gcgctagtga
    29521 tgacgctaag ggctgcaagg gtgaagaatg ggtgatttgt ctcccctgta gctggtagcg
    29581 tgctcttttg agctgctggt gctgacttag gcgctggtgc tttaggctga gctgattttt
    29641 ctggagcctt tggtgcaggt gtcttttcag gtgcttttgg agctgatggt tttgtatctt
    29701 ttccttgatc accctttggt ttttgctcgc ctttttcgcc gcgttgtcct tgctcgcctt
    29761 tttcgccgcg ttgtccttgc tcaccttttt caccgcgttg tccttgctca cctttttcac
    29821 cgcgttgtcc ttgctcacct ttttcaccgc gttgtccttg ctcacctttt tcaccgcgtt
    29881 gtccttgctc gcctttttca ccgcgttgtc cttgctcacc tttttcaccg cgttgtcctt
    29941 gctcaccttt ttcaccgcgt tgtccttgct cgcctttttc gccgcgttgt ccttgctcac
    30001 ctttttcgcc gcgttcgcct ctgtcaccct tagggccggc tggtccttgt tcacctttag
    30061 gacctgtttc tccggtttcg cctttatctc cacgtggtcc cataggccca acaggacctt
    30121 gctctccgcg ttcccctcta ggtccggcag gccccacagg tccctgagga ccaccttttt
    30181 tagcttgtag ttctaagttt tgtaagtagg tttgcatgaa ttgtcttaat gtatgtaggt
    30241 atactcttac ttcgccatct ccgagtccgt ccctaattag ttcagctgga tctggatagg
    30301 actctaatcg cgtataatct tcagctcggg catttccagc tgttcctagg ctggccattg
    30361 ttgctagggc aatggctgct gagcagacgc tgtacttgcg tattgttttt ttcatctttc
    30421 tctcctttga tgatagtatc attacttttt caaaattctt tcccgaagaa gagtttaaca
    30481 tggtagcttg ctatgagaaa cagctaggcg ccactttgtc tccgtagttt ttttaattca
    30541 atgctgaatc gtctgatttt atcagagggt tattgttttt aaaggcgagg agttgctttg
    30601 ctcagctagt ctagcaagtt cacaggtcag cttatgtttc ttatcaagct tgtttgtttt
    30661 tgagaatatt tttcgataaa aagatgttgt attaatattc atgttatagt ataattatat
    30721 tcgttgccat gactttatga atgttaggag ataggaatgg attttacctt tttacccaaa
    30781 tactgggctt atttcaatta tggtgtgctt gtaaccatga tgatttcagc ctgtgttgtc
    30841 ttttttggca cgattatagg tcttttagtg accctgataa aacgcagtca tatcaagcct
    30901 ttgtcttggc ttgtcagtct ttatgtctgg atttttcgtg gaacgccgat ggtggtacag
    30961 atcatgattg cttttgcttg gctgcatttc aacgatctgc ccattgtagg ctttggtgtg
    31021 ttggatttgg atttttcaag actgcttcct ggtattatta ttatttcctt gaatagcggt
    31081 gcttacatat ctgaaatcgt cagggctggg attgaggcgg tgccaaaggg gcagctggag
    31141 gctgcttact ctcttggtat ccgtcctaag aacgccatgc gctatgtgat tttgcctcag
    31201 gcctttaaga atattttgcc ggccttgggc aatgaattga tcaccattat caaggatagt
    31261 gccttgcttc agacgattgg tgtgatggag ctttggaatg gagctcagtc ggttgtgacg
    31321 gcgacctatc tgcctattac acccttgctg tttgcggcct tttattactt gatgataaca
    31381 acaatattgt cgcaattatt aggctgcttg gagcgcaagc tagcacaggg agggagataa
    31441 gatgactgag acagtgattt cgattcgtca gttgcataag agctttggca agcatgaggt
    31501 gctaaaagga atagacctga ccattaatca gggtgaggtt gtggtgatta ttgggccatc
    31561 tggctcagga aagtccacgc tattgcgcac gatgaatttg cttgaggtgc caacaaaggg
    31621 acacatcagc tttgagggcg tcgatattac ggataaggca aatgatattt tcaagatgcg
    31681 tgagaagatg ggcatggttt ttcagcagtt taatctgttt cccaatatga cagtgctgga
    31741 aaacatcacc ctgtcaccca tcaaaacaaa aggaatgtca agggctggcg cggagcagag
    31801 agcttatgag ctgcttgagc gagttgggct gagagataag gctgctgcct atccggcaag
    31861 cttatccggt ggtcagcagc agcgcattgc gattgcgcgc ggcttggcaa tggatcccga
    31921 tgtgctgctc tttgatgagc cgacctcagc gcttgaccct gagatggtgg gtgaggtttt
    31981 ggctgttatg caggatttgg caaaatcagg catgacgatg gttattgtaa cgcatgaaat
    32041 gggctttgcc aaagaggtgg cggatcgcgt gatttttatg gacggtggtc ttgtgattga
    32101 agagggcagt ccagttcagg tatttgaagc tcctaaggag gagcggacca aggacttttt
    32161 gagcaaggta ttgtcatagc tggcgcagct aaagggcagc atgtcacctc aaggtctggc
    32221 tattagtcaa ttggctgttt gttttgggca ttttgtttgt aaaaggctta gaaagtctgg
    32281 ttggtgctgt agccatatct ggctttgcta cgcttgggct gctagctggt cagtgggtat
    32341 catagtgatt ggaggtgtgg tctctttatt ggtcaacatt gctgtggcag gctagcacag
    32401 gggctttgct tgttgtgctg ggtaaggggt ttcatttgca tgactgttaa cattgcttaa
    32461 ttgatgaatt aggttgactt ttgttttatt gtttgatact attcaggtaa gtctgtcatt
    32521 agaaagcgct ttgctttttt gatgatggaa atcatgatca tatgatcacg tcttaggtaa
    32581 tatgttgttg tcaacatggt ggtctgaaag taggaggata atatggacta caaagctgtt
    32641 tatcaggagt ggctgcacaa tgattttttc aatgaagaaa tcaaggcaga tttagaggcg
    32701 attaagcatg atgaggctga gattcaagac cgtttttata aggtgcttga gtttgggaca
    32761 gcaggactta gaggaaagct cggtgctggg accaaccgta tgaatattta catggttggt
    32821 aaggctgcgc aggctttagc taataccatt attgatcatg ggccagaggc agtctcacgc
    32881 gggattgcca tcagctatga tgtgcgctat aagtctaagg aattcgcaga attgacctgc
    32941 tcgatcatgg cagccaatgg gatcaagtct tatatctaca aggggattcg tccgacaccg
    33001 atgtgctctt atgcgattcg tgccttgaac tgtatctctg gtgtcatgat tactgctagt
    33061 cacaatcctc aggcctacaa tggctacaag gcttattggg aagaggggtc acagatccta
    33121 gatgacattg ctaatcagat agcggttcat atggacgcta ttgagcgctt tgaggacgtt
    33181 aagcagatac cctttgagga ggcattggca agtggtctga ccagctatat tgatgatagt
    33241 atagaggagg cctataagaa agaggtttta ggcttgacca tcaatgatac tgatattgat
    33301 aagtcagtgc gtgtggttta tacacctttg aatggcgttg gtaatttgcc tgttcgtgag
    33361 gtattgaaga gacgaggctt tgatcatgtc tttgtagtgc cggagcagga aatgccagac
    33421 ccagatttca caacagttgg ttatccaaat ccagaggtac caaaggcctt tgcttattca
    33481 gaaagactag ggcaagaagt aggagcagct attctgattg cgactgatcc ggactgtgat
    33541 cgtgtggcac tagaggttcg agctgctgac ggtagttatg tctttcttaa tggtaataag
    33601 attggtgctt tgttgtccta ctatatcttt tcacagcgtc atgctaggca taatcttcct
    33661 gacaatcctg tccttgtcaa atcaattgta acaggggatt tatcaaaagc tattgccgct
    33721 aaatatgacg ttgaaacggt tgagactctt acaggcttta aaaacatctg tggtaaggct
    33781 aatgactatg acatcacaaa ggagaagacc tacgtctttg gctatgagga aagcattggt
    33841 ttttgttacg gtacctttgt gcgtgataag gacgcggtta gcgcctcaat gatggtggta
    33901 gaaatggctg cctactacaa gcaaaggggt cagtcactct tagatgtgct tcaagacatt
    33961 tacaaggaat ttggctatta caatgagcgt caggtagcgc tagagctaga gggtgttgag
    34021 gggcagaagc gtattgcacg tatcatggag gactttagaa atgagcctat tgagcatgca
    34081 ggtgctatga gcttgaagac cattgtagac tttaaggacg gctaccttga ttttccaaag
    34141 caaaattgtt tgaaatatta ttttgatgat gggtcatggt atgcgctgag accatctgga
    34201 acagagccta agatcaagct ttacatctat actattggtg aaacagaggc agacagcatt
    34261 gctaagctag acgctattga gtcagcttgt caagcaaaga tggacagtgt cagctaattg
    34321 ttcaagctct gcaacagaaa atcagctaat caataagcaa aaaggaaaag gaagtgacag
    34381 tgcttccttt tttcgttata atagttaaaa aattagcaag gagtgcatat ggtacagatt
    34441 attgatggga aggccctagc acagaaaatg caggcagcat tggctaagaa ggtagagagc
    34501 ttaaaggcag aaaaaggaat tgttccaggc cttgttgtca ttctggtagg agacaaccct
    34561 gctagtcagg tttacgtccg taataaggaa cgcgctgcct tagcagcagg ctttaaaagt
    34621 gaaaccgttc gcttgtctga ttcagtctgt caggaagagt tgatagagct cattgagcaa
    34681 tataatcaag atgatacgat tcatggtatt ttagtgcagc ttcctcttcc gcaccatatt
    34741 aatgacaaaa gcattatcct tgctattgat cctaaaaagg acgtcgatgg ctttcaccct
    34801 atgaatacag gtcatctgtg gtcaggtcgt ccgaatatgg tcccttgtac tccggcaggg
    34861 attatggaga tgtttcatga ctatggtatc gaacttgaag ggaaaaatgc tgttattgtc
    34921 gggcgctcaa atattgttgg gaagcctatg gcgcagctac tgttggataa aaatgctacg
    34981 gtaacgctta cccattcgcg cacgcgccga ctggcagata tttgtcgtcg tgctgatatc
    35041 ttgattgttg ctattggtca ggggcatttt atcacaaagg agtttgttaa agagggtgct
    35101 gttgttatag atgttggtat gaatcgtgac gtcaatgggc gattgattgg agacgtcgcc
    35161 tttgatgagg tgtcagagct ggctagcatg attactcctg ttccgggtgg tgttggaccg
    35221 atgaccatta ctatgctttt ggagcaaacc tatcaagcag ctctaagaag ggtgagtcaa
    35281 tgattataga tcaatcgttt gttgctaggg ttgttgttcc gcggcaggct gactcccata
    35341 aggggagtta cggcagagta ctgttagtag gtggcttgta tccatacggt ggtgctatta
    35401 ttatggtagc gctggcctgt gttcatagtg gtgctggcct agtaactgtt gcaactgata
    35461 gagaaactat tgctgccttg catagtcatt tgccagaggc gatggctatt gcggtagatg
    35521 atgaggaatt actgttatct cagctaggta tggcagacct gattttgatt ggtccggggc
    35581 tgtcggagaa tagcagagca gctaggctgt ttgaattggt ccttgcacat gtcgctgatc
    35641 atcaggtatt ggtcattgat ggctctgcct taaggctttt agcgaaaagg gcagctgatg
    35701 ttaagcagct gaggtgccct cttgtgttaa cgccacacca aaaggaatgg gaggcgctgt
    35761 caggtttagc gattgatcag cagtatgatg ctgccaacca agcagctctc aagcattttc
    35821 caagggctac gattttggtt gctaaaagct cagcaaccaa gatttatcat ggcaaccaga
    35881 tctaccggct aagagtgggc ggaccttatc aggctacagg tggtatgggg gataccttgg
    35941 caggtatgat agcagggata gctgtccagt ttccagagtc aagcttggtg gctaaggttg
    36001 cttgtgcgac ctatctgcac tctgcgattg ctgatgagct ggcaaagact gcctatgtgg
    36061 ttttgccgac tgctattagc tatgagcttc ctagatggct aaaggcaatc agcacaggcc
    36121 agaagctagg ttgaggctgt gctgcgaggt cgtttgggaa aagcggttaa ttggtaggca
    36181 tgacagcagc tggtttcagt cgtttagcta ttttgagttt agagctgcta gcttaagact
    36241 gggtgctgct ttatgattca aggaagctat cattggaaaa acttgtgtca agctgtagaa
    36301 gccctagctg gcttcttttt ttgtctcttt tttgctcact atttatgtgg aaacatgata
    36361 taattgcatt agtatacagt tggagcagtt aggcttcatg aagtgaaagg taaactgatg
    36421 gcagactatt tatccgtcac tcagctgaca aaatatttaa aattgaaatt tgatcgagac
    36481 ccttatctgg agcgtgtcta tctcactggt caggtatcta atttcagaaa aagaccaaat
    36541 caccaatatt tttccttaaa ggacgaggga gcggtgattc aggccaccat gtgggcagga
    36601 gcttataaaa agcttggctt tgatttagaa gagggcatga agctcaatgt ggttgggcgt
    36661 attcagctct atgagccaaa tggctcgtat tcaatgatca ttgaaaaggc tgagccagac
    36721 ggtattggtg ctttggcgct gcaatttgag cagctcaggc aaaagctggc tggtgaaggc
    36781 ttctttgatg agaggcataa gcaggccctg ccgcaatttg tgacaaaggt aggtattgtg
    36841 acgagtccaa gtggggctgt gattcgtgat attatcacaa ccatctcaag gcgttttcct
    36901 ggggtgagta ttcttttgtt tccaacaaag gttcagggtg agggggcagc tcaagaggtt
    36961 gctgctaata ttactaaggc taaccagcgt gaggatctgg atttgttgat tgttggacgc
    37021 ggcggtggct cgattgagga cctgtgggct ttcaatgagg aaatcgttgt tcaggctatt
    37081 tttgagtctc gcctgcctgt tatttccagc gtaggacatg agacagatac aaccttggct
    37141 gattttgtgg ctgatcgcag agctgccacc ccaaccgcag ctgcagagct ggcgacacct
    37201 attacaaaaa cagatattgt ctcttggatt gctgagcagc agagccggtc ctatcaagcc
    37261 tgtctgcgct atatcagaca agggcaggag cgggtggata agctttctta ttctgttatt
    37321 ttcaggcagc cagagaggct ctatgatgct tatagtcaac gcttagatag gcttacgacc
    37381 tccttgatga ccacttttaa agagacatta tcaggagcta agcaggagca cttgattttg
    37441 gagcatcgtt tagcctctgt caatgtacag gcaaggcttg agcgttatca ggatcgtctg
    37501 gcaactgcgc atcgtctctt gatagccaat atgaccaatc aatatgacag taagctagca
    37561 ggctttgagc gagctcaagc tgccttgctg tcgcttgata cgagccgtat cattgcccgc
    37621 ggctatgccc tgttaaaaaa ggacggtgta gtagctgctt gtgttaagga cattaaaaag
    37681 ggagatcatc ttagtattat catgcgtgat ggtcaattag aagtagaggt agaagatgtc
    37741 aacgaaaaaa atatttgaag agcgtttaca agaattagag gccattgtga cgaggctaga
    37801 aaatggtgat gtgccactag aagaggccat ctctgaattt caaaagggta tggtgctgtc
    37861 caaggacctt caaaaaacct tacaagcagc tgaaaagaca cttgttaagg tcatgcaggc
    37921 agatggcaca gagctagaaa tggatgccta atggataagc taacaagaat taatgccacg
    37981 attcatcagt attatgacag gcagtctact gtttcagcag atctggagga ggccatttta
    38041 tattctgttg atggtggagg aaagaggctc cgtccactca tgttattgga gctgctagag
    38101 ggctttggtc ttgccttgac agacgctcat tacgcggttg ctgctgctgt tgagatgatt
    38161 catacaggaa gtttgattca cgatgatttg cctgctatgg ataacgatga ttaccgtcgc
    38221 gggcgactaa ctagccacaa gcaatttaat gaagcaactg ctattttggc aggagatagt
    38281 ctttttttgg acccttttgc tctaatcgca ggggcagatt tgccggctga cctgctggtg
    38341 caattgattc agcagttttc cttagcgtca ggaacctttg gcatggtcgg tggtcagctc
    38401 ttggacatga agggtgagca tcagctgctg gatattcagg agctatctga tattcatgcc
    38461 aataaaacag ggaaattgtt gacccttcct tttgtggctg cgggtatcat agctgagcag
    38521 tcagcagacg ttttgtcttg tctgtgggag gctggtaggc ttgttggaca ggcctttcag
    38581 ataagagatg atatattaga ccttacggct agctttgctg atcttggcaa gacaccgcaa
    38641 aaggaccttg ctgctgcaaa atcaacctat ccgagtctgc ttggtttaga gcgctcaagg
    38701 gctattttgg aggagtcttt gagtcaagcg ctagctattt ttagcagact agaaagggaa
    38761 gaaggctttg agtctcaggc tattatcaaa aggatcgagg ggttgcgact aaatggctaa
    38821 agaaagagta gatgtgctag cctatagaca gggacttttt gaaacgcgag aacaggccaa
    38881 gcgcggtgtg atggctgggc tagttatatc agctataagt ggcttacgct ttgataagcc
    38941 tggtgaaaag attgatgagg ggatcgaact aaggctcaag ggtgagaagc ttaagtatgt
    39001 cagccgaggg ggtctcaagc tggaaaaagc cttgcaggtc tttgggatct ctgtgcagga
    39061 taaggtgaca attgatattg gtgcttcaac aggtggcttt acagatgtta tgctacaggc
    39121 aggagctagg ctggtttacg ctgttgatgt tggaaccaat caattggtct ggaagctcag
    39181 gcaggatagt cgtgttcgaa gcatggagca gtacaatttt cgctatgcaa agctagcaga
    39241 tttttcagaa ggtcagccag cctttgccag cattgatgtg tcctttattt ctcttagcct
    39301 gatactgccg acattgcact gtattttgca ggaaggggca gaggctgttg ctctgatcaa
    39361 gccacagttt gaagcagggc gcgagcagat tggcaaaaaa gggattgtca aggatagact
    39421 gattcatgaa aaagtgatta agcaggtggc agatactgct cttaattgcg gatttatcgt
    39481 taaggggctt gatttttcgc ctatccaagg tggtcatggc aatattgaat ttttggctca
    39541 tttagtcaag ggaaagggct ccaaggctat tgatgatcag ctcatacaga gcgttgttag
    39601 cagtgcacat aaggaattta aacagcatga aaaagagtga acgattagat ttaataaaaa
    39661 aaatggtttt gtctcatgag attgagactc agcatgagct attaaagctc ctagctgatt
    39721 atgggctaga gctaactcag gccactattt caagagacat gaatgaaatt ggcattgtca
    39781 aaattccatc tggaactggg cgttatgtct atggcttgtc acaggatagt ggcaagcggg
    39841 tggtgcaaag gcctgcctct atcaaaaaaa cgattttgga aatgtctgaa aaaacagcgg
    39901 gcttggagca gcatattcac ctcaacgttg ttccaggcaa tagcaagcta atcaaacgtt
    39961 atttgatgac agacttttca ggtcaattgt ttagcctgat tgcagatgat gatagtttgc
    40021 tgttgattgc aaaatcagaa gcagacgctg atcatatccg tcaggaattg tccctttgga
    40081 tgcagggatt ggtctaaaaa atagagagaa gccgatgtta ttagaaattt ccattaagaa
    40141 ttttgctatc atagaggaaa tctctttaaa ctttgaaaac ggtatgaccg tactgactgg
    40201 ggagacaggg gcaggaaagt ccattatcat tgatgcgatg aacatgctgc tgggtgcgcg
    40261 cgcaagcact gaggtgattc gacatggtgc tgataaggca gagattgagg gcttcttttc
    40321 ggttgatgct aatcctcatt tagccgctgt gctggcagaa tcagggatta gcatggaaga
    40381 ggagttgatt cttcgtcgtg atatttttgc taacggtcgt agcgtcagcc gtatcaatgg
    40441 tcaaatggtc actgtcagca ccctaaaaaa acttgggcag tttttagtgg atattcatgg
    40501 tcagcatgat caggaggaat tgatgcgtcc acagctgcac cagcatattt tggatagttt
    40561 tggagatgag gcctttgacc agctcaagca gtcctatcag cagatttttg atcgctataa
    40621 ggctttgcga aggcaggctc ttgagaagca aaaaaatgaa aaagaacatc aggcgcgcct
    40681 tgacctgctg gcctttcaga taggggaaat tgaggcagca gatttggtta gaggagaaga
    40741 tgacctgctt aaccaagaaa ggcagcgatt gctcaatcac aaaaagattg ctgatacctt
    40801 aaccagtgcc tacctttcct tggataatga ggacttttcc agtctctcac aggtccgctc
    40861 tagcatgaat gagttgctgt ctattgagga ccttgcccca gagtatcagc ttatatcagc
    40921 tggtgtgtca gaggcttatt atattcttga ggaggtcaca aagcaattat ctgataccat
    40981 cgaccagctt gattttgatg caggcagatt gcaggacatt gagctgcgtt tagacagcat
    41041 taatagtctg acaagaaaat atggcggtgg tgtgaatgat gttttggact actatgccaa
    41101 tattaccaag gaataccagt tattaagcgg agatgaccgt tcctctgatg agctagaaag
    41161 ggaattaaag gtccttgaga agcaactggt gatgactgcc tcacagctaa gtgacaagcg
    41221 tcatgccctg gctctagagc tagaagccga catcaaagct gagctgagag agctttatat
    41281 ggaaaaggcg gactttaagg tccactttac aaggtcaaag tttaatcgag aaggcaatga
    41341 aagcttagaa ttttatatct caaccaatcc aggtgagggc tttaagccgc tggttaaggt
    41401 tgcttcaggt ggtgagcttt cccgcttgat gcttgctatc aaggctgcca tttctaaaaa
    41461 agaggacaag acgagtattg tctttgacga ggtggatact ggagtttcag gacgtgtggc
    41521 ccaggccatt gctaaaaaaa tatataaaat tggcagctat ggtcaggtat tagcgatttc
    41581 gcatttgcca caggtggttg ctattgcaga taaccagtat tttatttcca aggaaagcaa
    41641 ggaggagtcg acagtgtcta aggctaagct gttgacacag gaggagcgga tcgaggagat
    41701 tgcgaagatg attgcaggag ctgatgtcac agagacagca agaaatcaag cgcgtgaatt
    41761 gctaggtaag gactgagtat catagcaaaa gcagaacagt agctttagag caagcttgcc
    41821 tgctgcactt gtcgctacat gttcagaatg agccacctga aaggcaagca agaaggctag
    41881 ctcttatgcg tatgctatca gaagctaagt ctttttgtct cttgcattgg cgagtgattg
    41941 attgataata ttatgataaa tagaaggact aaaagaatac tgactgagga ggtaaaatgc
    42001 tgaaaaaaag aatgggcttg gctagtctgc tagtgttgat gacctttgtg tatcagtgct
    42061 gttcagttac tgctgagcag tattccgata ctgaggttga ggtgctgcag attagcgagg
    42121 agaaaagcca gatcatggaa aatcaagagg cgcttaaaga cctcaccacg tcgtctgatc
    42181 agctaaagaa ggaagcttta aagcctaaag aggcagctac caacaagagc aagcaagagg
    42241 cttcgacagt ttatttagct gaggacgatc ctgtaaccat tgatagctct gacgaggaaa
    42301 gcaatcaaga tatcatagcg gattctgttc ctgatttggt tattaaaggt gatcaggtgg
    42361 atgtatctga ggttatggtc tctgtaaagg aggattcatc gaaagttgct aagcaaagaa
    42421 ctgacgcagc gcagcggtac agtatagcca agcatcaatt gacccaaaag cttgaggcct
    42481 ttaatgcggc aacggaccaa ttgctgacca tgattgctaa aaaatctgat ttgactggtc
    42541 agtattatgt ggttgggcat tcgttgggag aaatgctggc tgctcaaaat gagaaaaagc
    42601 ttgctgagca attagtcatg caacaaaagc acaaaaaagg cttaggctca tcagtcacta
    42661 ttttagacga attaggacgt gtgatttctg acattagtgg tcataaaggc atgcttcctt
    42721 ttaatcgtaa gatcagcttt aaggtacatc aagtcagata cgatcttcca ctaactggtg
    42781 atcgaacagt gctacctgcc cagctggctg gcttactgct tttactaata ggtcttatgc
    42841 tgcctaaagt agctaacaag aaaagctaag atatggtctt ggctttttta tcttttaaga
    42901 gggtgagttt ttgacagatg ttttagctaa caccaagagc tagataccag ctttgcttta
    42961 tttttaaagg agtgataaaa taaagagacg ataaatgagg ttagaaatgg aacttaagat
    43021 gggaactatt aaaattgttg cagattcatc aatgacgatt gaaccagagc taatcaaatc
    43081 tcttgatatt acggttgtac cgctttctgt catgattgat agcaagctgt attctgataa
    43141 tgagctaaaa gaggaagggc aatttctaca gctgatgaga gctagtaagt cattgccaaa
    43201 aactagtcag ccaccggtag ggctttttgc agatatttat gagcgattgg tcaaggaggg
    43261 ggcgacagct attgttgcca ttcacctctc accagctctt tcaggaacaa ttgaggcatc
    43321 acgtcaggga gctgaaattg cagcagcacc agttacggta ttggactcag gctttacaga
    43381 tcaggctttg aagtttcagg tggttgaagc ggctagactg gctcaagctg gcgctagcct
    43441 tgaggaaatc cttgaggcgg tagaggatat taaacgaaag acagagcttt atataggggt
    43501 atcagcactt gagcacttgg ttaagggggg acgaatcggt cgtgtgacag gcttgcttag
    43561 ctccttgctg aatattcgtg tggtcatgga aatgaaaaat gataccctgc aaacacttgt
    43621 taaaggacgc ggcaataaga cctttactaa atggctggat agctatctag cagaaaatag
    43681 ccagcgacag atagctgagg tggccatttc ctatgctggt cagagggatt ttgctgatag
    43741 cctgaagaag acaatcgcta cggtctttga tgggccaatt actgttttgg agactggctc
    43801 aatcattcaa acacatactg gcgagggcgc ttttgcggtg atggttagat atgaataagc
    43861 gagggttttt gggaggcctt atcttctttt tcagtgtttt tgccttatca tttgtgatat
    43921 tagctgtcct tattccaaag tctgacccac agctgaagaa aagtgatttt ctaaaaaata
    43981 agaagataag cctcaattat attgctattg gagactcctt gacagaggga gtgggtgatc
    44041 tcaccaacca aggaggcttt gtgcccttat tgtctggtga tcttggagac tactttaatg
    44101 ctaccgttaa tactgaaaat tacggtgttt ccggtaatac cagccagcaa attttaacga
    44161 gaatgactga gaacaaggag atcacagagc agctcaaaaa agctaatctc atgacattaa
    44221 cggttggtgg caatgatgtc ttggctgtta ttcgcaagaa cttagctaat cttaaggtat
    44281 caagctttaa aaagccagca aggcaatacc aagagcgctt acgcaaaatc cttgatttgg
    44341 ccagaaagga taatcaggat ctgccgatct ttgttttagg tatctacaat cctttttatt
    44401 tgaattttca ggagctaaca gaaatgcaga cggtcattaa tgactggaac aaaaaaacac
    44461 aagaggttgt tgatgactat gaccatgttt actttgttcc aattaatgat ctattgtaca
    44521 aaggagtaga tggtaaagag ggcattgtcc agtcaacagg agagcaaaca acgattgtga
    44581 atgatgcttt gttttcaggg gatcattttc accccaataa cacaggctac caaatcatgt
    44641 cagacgcagt aatggagaca ataagaaaga atggaaaaga aattaaacct taattggtgg
    44701 aaatgggctt ttttgctatt attggctttt aatgcagcct ttttagcagt tattggaagt
    44761 cgtattatac aaataagaga gcctaagtct gagctgatca atcaaaaagc agcaaagaat
    44821 attaaaatag ggaccttaac aaccactaaa gagcaattaa atgaggcagt cgttagctac
    44881 ctaaaggatt ttcagacgga aaaaatgacc tataaggtgt atgccacctc ctcgaccatt
    44941 ctctttgaag gaacctatca gctcttagga tatgaggtgc cgttatacat ttattttcag
    45001 cctcatcgct taaccaatgg tgcgatacag ctgcaggttc tctccttttc tgtggggacc
    45061 ctttctttgc cggaaaagga cgttttgcaa tacttgaaat ccagctataa gctgccaaaa
    45121 ttcgttgaag tcttacctaa gcaatcggct attattatca atctacagca attggaaaat
    45181 gatgccaaca tctatttaaa ggctcaaaag attgatcttg tcaaggatga tattcgattt
    45241 gacatctata agaaatgagt ctaactaacg tttaatactt gacctgtggc tgttttttag
    45301 atatgataat atctgttaaa gcgttaagct tactaattat ttggaggatt gttaaatggc
    45361 taacaaacaa gatttaatcg caaaggttgc agaagcaact gagcttacaa agaaagattc
    45421 agcagcagca gttgacgctg tcttttctgc aatcgaagct tttcttgctg aaggtgaaaa
    45481 ggtacaatta attggttttg gtaactttga ggttcgtgaa cgcgctgctc gtaaaggtcg
    45541 caacccacaa actggtgaag aaattgaaat tgcagcttca aaggttccag cattcaaggc
    45601 tggtaaagct cttaaggacg ctgtaaaata ataaatcaaa aaaagcccta tctcattaag
    45661 ctgtttagcc tgtgagatag ggctttttcc attaaggaag gagtcttgtt tcaataagta
    45721 atcttgtgtg atcgtctgaa agattagcgc caataatttc taatgtgcac tgtcttggga
    45781 acaagagttc catttcataa ggataaaatg agtagggctg tacaaaagca gcctggctgc
    45841 cttgagggac ctgaattctt aattccactg agcgatgtgg catagcagca tttttgatgg
    45901 ctgtagtact cataaagcct tgctttgtat aatgagtgcc tggcttgatc gctgatagga
    45961 tctgcggatc aaaggtctta tcatggtagt aacgagcgag ttcctcttca gaagtgccca
    46021 attctgttaa gaatgtttca taaacatagc gatagacgat gatattccaa gggatggtta
    46081 gcttatgagt agcactatca agtaaggcta cagactgctg cagctgggca tccaactggc
    46141 tggtatctcc catcacctgt tctagggcta ggttaatagg gctggcagag gcgtatgtat
    46201 actgatacat catctttttt tctgcttctg taaaggctgt ttgagacctc cagcgattgg
    46261 tgataatgta tttggtaaca tcaggctcac taaatttata ataaggctta aagctattcc
    46321 catagggctc aaaaacaact gtttgtcctt catcataaga ctgtgccttg atggttgaag
    46381 gctgaacgac aagcaacgat aagaaaaatg taaacaagca tagtgtacga atagctatcc
    46441 tttgataaga taactttgcg ttatgatgtt gatgagtcat ttagcttttc ctcctttaca
    46501 gtagtgccaa gagtgtcatc acctaatgat gatgtctgtt gctaacagga ttagccttag
    46561 ttgaaatgat taca
//
LOCUS       DARYXS010000006        46074 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.006, whole genome shotgun sequence.
ACCESSION   DARYXS010000006 DARYXS010000000
VERSION     DARYXS010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46074
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.006"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            69..683
                     /locus_tag="TV193_000247"
                     /pseudo
     CDS             69..683
                     /locus_tag="TV193_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1213..2091
                     /gene="mvk"
                     /locus_tag="TV193_000248"
     CDS             1213..2091
                     /gene="mvk"
                     /locus_tag="TV193_000248"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL1512488.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIMSQVPQKRGMGSSAAVSIAAVRA
                     VFSYFGQPLSDELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCFTEAVEQAIKTNDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVAAALEAGALGAKMTGGGLGGCMIALAERITDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            2073..3017
                     /gene="mvaD"
                     /locus_tag="TV193_000249"
     CDS             2073..3017
                     /gene="mvaD"
                     /locus_tag="TV193_000249"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL1512489.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEAKMIPSTSSISLTLEGMYT
                     TTSLSFLPASAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQTFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGWLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQEGYSCYFTMD
                     AGPNVKVLCLEEDLERLSHLFEREYRIIASKTKELPDV"
     gene            3010..4008
                     /locus_tag="TV193_000250"
     CDS             3010..4008
                     /locus_tag="TV193_000250"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL1512490.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYIDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVVLTLRALAAFYQVQLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRRKVGQWLIEMTLKELMAAHWGYTIETIEPALPCWFLVGWTQVPSISREM
                     IQLVNKSISCQFLEQSQLVTQEVMTALQLGQRKRLKASIEKAGQLLQGLASVIYHPKL
                     TQLVQACQGLDAAAKSSGSGGGDCGIALVFEAKDIEPILARWQQAGIVLLYQEEWG"
     gene            4011..5003
                     /locus_tag="TV193_000251"
     CDS             4011..5003
                     /locus_tag="TV193_000251"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL1512491.1"
                     /translation="MTNRKDDHITHALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVV
                     LELVETYPVEQIIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(5288..6571)
                     /locus_tag="TV193_000252"
     CDS             complement(5288..6571)
                     /locus_tag="TV193_000252"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL1512492.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDVANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSAKCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARTGSYRGLSSWHVDLSKNSLCGELTLPMPIASKGGSIGLNPT
                     VSVAHSLLEQPNAKVLAQITTAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAGQLLTAIRLSQS"
     gene            complement(6558..7733)
                     /locus_tag="TV193_000253"
     CDS             complement(6558..7733)
                     /locus_tag="TV193_000253"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL1512493.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAVCFHIPFPKLALKGLHKIMTKSLADDHKERLYENFQASIAYSKQIGN
                     IYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQA
                     LLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN"
     gene            7918..8757
                     /locus_tag="TV193_000254"
     CDS             7918..8757
                     /locus_tag="TV193_000254"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL1512494.1"
                     /translation="MTKADHIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRSIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWKAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACQPKLLLHVPDGTDFFDIRPEDFELQDYYPVKPQLTFD
                     LAI"
     gene            8838..9335
                     /locus_tag="TV193_000255"
     CDS             8838..9335
                     /locus_tag="TV193_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL1512495.1"
                     /translation="MTKKIIAIWAEDEAGLIGACGRLPWYLPKELQHFKETTLNQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTRDSYYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGYFDVIIKTVVHHQFEGDTYRPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            9355..9525
                     /locus_tag="TV193_000256"
     CDS             9355..9525
                     /locus_tag="TV193_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512496.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            9561..10790
                     /gene="clpX"
                     /locus_tag="TV193_000257"
     CDS             9561..10790
                     /gene="clpX"
                     /locus_tag="TV193_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL1512497.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLEILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMVQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVR
                     ITKEAVEGQSKPILEIA"
     gene            10800..11399
                     /locus_tag="TV193_000258"
     CDS             10800..11399
                     /locus_tag="TV193_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL1512498.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHESSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            11763..14765
                     /locus_tag="TV193_000259"
     CDS             11763..14765
                     /locus_tag="TV193_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL1512499.1"
                     /translation="MTIKKCPQILALFLAFAALASQGQTVHALERQETSVKQAHESDD
                     WFDEDEGVSDIKSNTPTEIDSTVTELFGDAEPKTKAEKEESKAPSPKQEALPAESQKE
                     KETSAKSTDHATVQAEEAQPEQGSDSPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLV
                     LPRIGIDKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRDILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERVFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHAVLRTKNGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNRWLAEDFTYTGQTITGFSASGLRKVKRNKHLVLPKNYQGQPLTAIADNA
                     FRNVNFHDKTLRKYDLESVTLPSTIQKIGAFAFQSNNLESFEASEDLVEIGQGAFMNN
                     RIEILALNDKLKVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVMFMGDKLIS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDSLMRIEAEAFKINRLQ
                     RVTVPDTVISISFNAFDHNSDDKVVLRTTNHNKNLLADGNGFIVDPDLLSADQSTVQA
                     VLEDLRRLDLASLRADTAAHFMTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKTADITLSSHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKVSRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKLLPKTGAF
                     KEAWVTMIGMLVLLAATLLKGDSRYKKK"
     gene            complement(14955..17048)
                     /locus_tag="TV193_000260"
     CDS             complement(14955..17048)
                     /locus_tag="TV193_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1512500.1"
                     /translation="MATYYGKDPFENMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAAAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEITK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGASDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDRADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLTEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            17419..17838
                     /gene="ndk"
                     /locus_tag="TV193_000261"
     CDS             17419..17838
                     /gene="ndk"
                     /locus_tag="TV193_000261"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL1512501.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDTLINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            18339..19145
                     /locus_tag="TV193_000262"
     CDS             18339..19145
                     /locus_tag="TV193_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1512502.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVVDTPVLNQSEKAVY
                     ANDFGSGNRASDYVPAANAWSFEAYPDYYSILGASHLNPAVFPEPSKMSYSPLDELGR
                     TQVARGTITYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     VPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTIDYATGAFRSN"
     gene            complement(19437..20402)
                     /locus_tag="TV193_000263"
     CDS             complement(19437..20402)
                     /locus_tag="TV193_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1512503.1"
                     /translation="MNNRNKRRKKRKIFKMINLMLLLACIIGLSAIVYLYKSHSKISI
                     SQLSQAIPKISLFSKTDKKPAPKPSKKATNKEASHTNSQQQKGAVSWTKQQNPVKLPI
                     LMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLSPEEAYRVLSANELPAE
                     KVVWLTFDDSMVDFYNVAFPILKKYDIKATNNVITGFTEAGNAANLTLDQMKEMKQAG
                     MSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIAIAYPAGRYTDTTLKIA
                     EDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNTISQ"
     gene            20574..21857
                     /locus_tag="TV193_000264"
     CDS             20574..21857
                     /locus_tag="TV193_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEL1512504.1"
                     /translation="MSVKVALLGFGTVASGIPLLLENNSSKIRAVVGDDLVIAKVLVR
                     DETTKKRLLDQGYSYQFVTSIDDIVDDESIDMVVELMGRIEPAKTFISRALSAGKPVV
                     TANKDLIALYGGELSTLAAKHQVALYYEAAVAGGIPILRALADSFASDKLTRLLGVLN
                     GTTNFMLTKMIDEGWTYERALQKAQELGYAESDPTNDVKGIDAAYKVAILSQFAFGMT
                     IDFEAISYSGIDKVRVEDVTVAQKLGYVIKLVGLLEETASGLNAEVSPVFLPKTHPLA
                     AVDGVMNAVYIESIGVGQAMFYGPGAGQMPTATAVVADMIQTACTLRDHTVSVFNRFA
                     TKTRLAKSEDIMSPYYFAIQATNKFGQLLELTRLCDVCGIRVEQLLSDEIDSDRLDFV
                     MITHEMSKKELACFTALLQDHQDFRMLSTFKILGD"
     gene            21859..22719
                     /locus_tag="TV193_000265"
     CDS             21859..22719
                     /locus_tag="TV193_000265"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEL1512505.1"
                     /translation="MKIRVPATSANLGPGFDSMGIAVSKYLEVDILEERDQWFIEHDL
                     GDIPNDDSNLLIQTALRLAPNIPAHRLKMTSDIPLARGLGSSSSVIVAGIELANQLGH
                     LNLTDDRKLAIATRIEGHPDNVAPAIFGQLVIASQIGKDVDYIIAPFPDLSLVCFIPD
                     YELKTSDSRDVLPKQLSYKQAVAASSVANLAIAALLTGNLKKAGRAIENDQFHEIYRQ
                     RLVREFQPIKRAAAANGAYATYLSGAGPAIMVMCPNKKKMAIYEAIEQLGLIGQLVSL
                     ELDRQGLCLV"
     gene            22884..24143
                     /locus_tag="TV193_000266"
     CDS             22884..24143
                     /locus_tag="TV193_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEL1512506.1"
                     /translation="MNYQETLDWIHGQERFGIKPGVKRMRWVLEQLGNPQDRIRGIHV
                     VGTNGKGSTVNDLQHIFTRAGYEVGTFTSPYIMDFKERICLNGEMISETDLVKAANCI
                     RPLTDRLISETSLGPATVFELITLIMFLYFGESHPVDIAIIEAGLGGLYDSTNVFQAM
                     AVVCPSIGLDHQAILGDTYADIAYQKAGVLKGGEDLIFAIDNKEARQVFLKKAEQLGV
                     PIWEWRRQFNMLQGEGGYQFNSQLGQLSHLVLAMPGQHQVANAGLATMTSLILQDRYP
                     KVTESVIREALASSFWLGRTELLAPNLMIDGAHNNESIAALIDVISSDYQDKQIHILF
                     GAIDTKPVSDMLQSLERLGDVQVTSFHYPNAYPLEAYPDRLTKVADFRAFLDRLEQAA
                     ADDFFLITGSLYFISEVRQYWKKVLSK"
     gene            24143..24766
                     /gene="folE"
                     /locus_tag="TV193_000267"
     CDS             24143..24766
                     /gene="folE"
                     /locus_tag="TV193_000267"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEL1512507.1"
                     /translation="MLSHINSSNKINQLKRGKPLPINQKKAEAAIYQLLEAIGEDPNR
                     EGLRDTPKRVAKMYLEMLSGLEQDAKDEFTAVFTEHHDDLVIVKDISFYSMCEHHLVP
                     FYGKAHIAYLPSDGRVTGLSKLARAVEVTSKRPQLQERLTAQIANALVDALQPKGVFV
                     MVEAEHMCMTMRGVKKPGSKTITTTARGIYKDSRDDRREVMQLIMEG"
     gene            24774..25574
                     /gene="folP"
                     /locus_tag="TV193_000268"
     CDS             24774..25574
                     /gene="folP"
                     /locus_tag="TV193_000268"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEL1512508.1"
                     /translation="MTIGHYSAAGEAAIMGILNVTPDSFSDGGSYTSVNQALAQAEKM
                     LSEGATVIDIGGESTRPGCQFVPAEEEIARVVPIIKAIKKRYDVLISIDTYKTETARA
                     ALEAGADMLNDVWAGLYDGQMLSLAAEYDVPIILMHNQTKEAYADVTKEVCSFLQARA
                     AAALKAGVKKEHIWLDPGFGFAKNVEQNIALLKGLNEVCQLGYPVLFGISRKRVVDAL
                     LGGGTKAKDRDGATAALSAYAINKGCQMVRVHNVGANRDIVSVLSQLR"
     gene            25581..25940
                     /gene="folB"
                     /locus_tag="TV193_000269"
     CDS             25581..25940
                     /gene="folB"
                     /locus_tag="TV193_000269"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEL1512509.1"
                     /translation="MDKIRLEACRFYGYHGAFKEEQVLGQIFVVDLELSVDLMAASLS
                     DCLEDTVHYGLVFETVRQIVEEKTFTLIERLAGAICQELFAQFLPIKAIKIAIKKENP
                     PIAGHYQAVGIELERKR"
     gene            25937..26443
                     /gene="folK"
                     /locus_tag="TV193_000270"
     CDS             25937..26443
                     /gene="folK"
                     /locus_tag="TV193_000270"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEL1512510.1"
                     /translation="MTLVYLGLGTNMGDRAGYLQAAVNALSKLPETELLRQSSIYQTA
                     AWGKTDQNAFLNMACQLDTRLTSEALLAATQAIEQALGRVRHEKWGPRTIDIDLLLFG
                     DEPYQSETLVIPHPYMTQRAFVLIPLLEIAPDVTLPGSQKSLRSYLDALEQSDVALWS
                     HEYSNKFS"
     gene            26539..27426
                     /gene="murB"
                     /locus_tag="TV193_000271"
     CDS             26539..27426
                     /gene="murB"
                     /locus_tag="TV193_000271"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEL1512511.1"
                     /translation="MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIV
                     DYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVRLNGYTLEAEAGANLIETT
                     KVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAR
                     EMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRKLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEDLIAHVIRTV
                     EQASGVRLEPEVRIIGESL"
     gene            27472..28626
                     /locus_tag="TV193_000272"
     CDS             27472..28626
                     /locus_tag="TV193_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512512.1"
                     /translation="MTKPIITFDNVSKTFEDSGTQVLKNINFELEEGKFYTLLGASGS
                     GKSTILNIMAGLLDATSGDIYLDGERINDLPTNKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKQEIARRVKETLKMVQLEGYEKRSIQKLSGGQRQRVAIARAIINQPRLVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVASFIGESNIINGTMIKDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIG
                     LDFTPEDIHIMRLNETEEEFDARIEEYVEIDEHADGLINAIEEERNEENL"
     gene            28610..29404
                     /locus_tag="TV193_000273"
     CDS             28610..29404
                     /locus_tag="TV193_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1512513.1"
                     /translation="MKKTSSLFAVPYFLWIVLFVMAPVALLLYQSFFDIEGRLTLANY
                     ETFFSSWTYLRMGLNSILYAGIVTLVTFLISYPTALLLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGLGPQQILFTDFSFIFVASYIELPFMILPIFNA
                     LDDIDDNIINASKDLGANDYQTFSRVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTENWGMGSTIGVVLIIAMIVIMWLTKEKSK"
     gene            29401..30177
                     /locus_tag="TV193_000274"
     CDS             29401..30177
                     /locus_tag="TV193_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1512514.1"
                     /translation="MKKFANLYLACVFILLYIPIFYLIVYSFNKGGDMNGFSGLTLEH
                     YKTMFDDSRLMAILLQTFVLAFTSALLATIIGTFGAIFIHQSKKKYQNAILSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGILSVLMSHIAFSIPIVVLMVLPRLKEMNQDMINAA
                     YDLGANHFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARRGISLDINALSTIVFLFSILLVIGYYYISQDKEEKHA"
     gene            30170..31243
                     /locus_tag="TV193_000275"
     CDS             30170..31243
                     /locus_tag="TV193_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1512515.1"
                     /translation="MRKLYSFLAGIIGVILLLATLSFILQKKTSSASQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEK
                     LLVKLDKSKLVGLDNIGQEFLGKSFDPHNDYSIPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYQNSIMLVDGAREILGVGLTTFGYSVNSKHLKQLEAAEKKLQALTPNVKAIVA
                     DEMKGYMIQGDAAIGVTFSGEASEMLDNNDHLHYVVPSEGSNLWFDNLVLPKTMKHEN
                     EAYAFINFIMKPENAAQNAEYIGYATPNTKAKALLPDDIKNDPAFYPTDETVKKLEVY
                     DNLGSKWLGIYNDLYLQFKMYRK"
     gene            31401..32933
                     /locus_tag="TV193_000276"
     CDS             31401..32933
                     /locus_tag="TV193_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEL1512516.1"
                     /translation="MENHKNEFTFSKHSIIAYVWRGILVGIIAGAIVSLFRLLIEMVS
                     EAVVGYYHQAHSNRMLLVPIAGFSLLAVFLVGLLVKSDANIKGSGIPHVEGELKGLMS
                     PNWWSVLWKKYLGGTIAISMGLMLGREGPSIQLGAMSAKGLAKYLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLVWITALVASLVANFISLNIFGLRPVLA
                     MPKAMPFLALHQYWLLLILGLVLGCLGFLYEEVILHFHRVYDFLGKSLRLAPHFHGLI
                     VVAIILLIGYYLPQLLGGGHGLIMSLSEQKLPLLTVLAYFFIRFLGSMFSYGSGLPGG
                     IFLPILTLGALSGTIFGLILQQIGLLDRQMIPLFLVLGMAGYFAAVSKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVAYLVMDLLNGQPIYEAMLEKMAIKHPTDLVEPTLIELPVS
                     EKIAGRYVRDLKLPKNVLITTQLHHKKSQVVSGDTLLISGATIFLVVNEADTGFVREV
                     LM"
     gene            33139..33753
                     /locus_tag="TV193_000277"
     CDS             33139..33753
                     /locus_tag="TV193_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEL1512517.1"
                     /translation="MLEVISKELRHYQKNKLAAYQKKNQGIEAGGIVFAGDSLIEFFP
                     LKKYFKQVSTIYNRGIAGIDSQWLLEHIDSHVNDLEPSHVFILIGCNDIGLGFDQSHI
                     VSTIVDLISRIRSQSIYTRISLLSLLPVSENPAYQATVKLRTNRAIDEINQALAMIPA
                     IEFIDLNACLKDETGGLAAAYTVDGIHLNALGYEHLAQAISPYL"
     gene            34101..35228
                     /locus_tag="TV193_000278"
     CDS             34101..35228
                     /locus_tag="TV193_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1512518.1"
                     /translation="MKFEKKQVFYVVLAFVLCYAIQANWDNGANIVTTVYKTSLPFLY
                     GAAVAYIVNIVMSAYERAYTYTLKPFPFAMKARRGLCMLLAYFTFISLIVWIISIVIP
                     DLIASISSLTQFDTRAIKEVISDLGHNKLIARAINYIGGDAKLTETITNYSQQLLKQF
                     IGVLTGILTSVTAVASAIINVVISFVFSLYVLASKEELCQQATTLIDTYTGKYAKAIH
                     YLVGLLHSRFRGFFVSQTLEAMILGSLTAIGMFILQLPFAGTIGVLVAFTALIPVVGA
                     SIGAAIGFVLIMTQSMSQAVVFIVFLVILQQIEGNFIYPRVVGGSIGLPAMWVLMAIT
                     IGAALKGIVGMIVAVPLAATLYQVVKDHIHKKQALQNRQSS"
     gene            35380..36057
                     /gene="radC"
                     /locus_tag="TV193_000279"
     CDS             35380..36057
                     /gene="radC"
                     /locus_tag="TV193_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEL1512519.1"
                     /translation="MYSIKTDHKLMPRERLIRLGPEKLSNQEQLAILLRTGNKEKHVL
                     ELSAYLLSSLDSLADLKKFSLQELQRLSGIGKVKAIEIKAMLELADRIQIAGQAVADP
                     VLSSAQVAEKMMIELGDKQQEHLVAIYLDSQNKIIEEKTIFIGTVRKSIAEPREILYY
                     ACKNMATSLIVVHNHPSGLTKPSANDYHFTEKIKRSCDYLGLICLDHIIVSKYDYYSF
                     REKSDLF"
     gene            complement(36059..36754)
                     /locus_tag="TV193_000280"
     CDS             complement(36059..36754)
                     /locus_tag="TV193_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEL1512520.1"
                     /translation="MSKTIIGITANQRGTKALDNLPCSYAPTSFIEAVTRSGGLPLLL
                     PIGDEAAAKSYVAMVDKIILIGGQHVDPKYYHEKRAALDGDFSPQRDIFELAIIKEAL
                     AQKKPILGICRGMQLINVALGGSLNQHIEGHWQKTASDCLSQEIVIEKTSPLYPIYGP
                     RALINSFHHQSLKQVAEDLRVIARDPNDGTIEAVISCNPDIPFLGVQWHPELLQAIRE
                     EDLRLFDWFIHSF"
     gene            complement(36766..37410)
                     /locus_tag="TV193_000281"
     CDS             complement(36766..37410)
                     /locus_tag="TV193_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEL1512521.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFYADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTHVILVGCGNIGRALLHY
                     RFHDRNKMQIVMGFDTDDNPMVGTKTPDDIPIYGISTIKEHLDNSGIETAILTVPSIY
                     AQEVADQLIEAGIRGILSFAPLHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(37696..38043)
                     /locus_tag="TV193_000282"
     CDS             complement(37696..38043)
                     /locus_tag="TV193_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEL1512522.1"
                     /translation="MAFEKEIALKDCKYSYRISPKIKKYTLRDTTFSQTKIGHYQLTR
                     LLEKVPNSGEGFPLKITINKDLDGFKLAITDQSGLRLVNIFKSEEHSILQDKFYFLMD
                     SLVERDIFIKKEC"
     gene            complement(38033..39160)
                     /locus_tag="TV193_000283"
     CDS             complement(38033..39160)
                     /locus_tag="TV193_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1512523.1"
                     /translation="MIYFDNAATTSLSQAAIKAMTEAMADDFGNPSSIHAYGRQANKQ
                     LRECRKAIANCLGAAENHIIFTSGGTESNNTAIKGYALAHQEKGKHLITTAIEHHSVL
                     STMAYLEERFGFEVTYLEAKNGIIDLNQLQAALREDTILVSMMFANNETGDLLPIQAV
                     GSMLKQHQAVFHVDAVQAIGKVPIQPADLGIDLLSASAHKFHGPKGTGFLYNKGLKLA
                     PLLHGGNQENKQRAGTESLINIVGMTQALDEAVSRLPQHYQHAKELSQLLLSELEGIS
                     YQLNHNECHLPYIINIGFPGYQNHVLLTQLDLAGFAVSSGSACTAGAVEPSHVLAAYF
                     GKQSHRLTEAIRVSFSEQNTQKDVIALATQLKNILGGSYGI"
     gene            complement(39163..40137)
                     /locus_tag="TV193_000284"
     CDS             complement(39163..40137)
                     /locus_tag="TV193_000284"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1512524.1"
                     /translation="MTERYADKQIKLFSLTSNLAIAEKISKAAGIPLGKVSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKSREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAKH
                     YYPLGLSGPDTVIVSPKNSGIKRARSLAEYLNSPIAIIDYAQDDAEREEGYVIGDVAG
                     KKAILIDDILNTGKTFAEAAKILECAGATDIYAVASHGIFAGGAADILETAPIKEIIV
                     TDSVKTKNRIPKTVTYLSASDLIAEAIIRIHERKPLSPLFSYKPESTN"
     gene            complement(40272..40844)
                     /locus_tag="TV193_000285"
     CDS             complement(40272..40844)
                     /locus_tag="TV193_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEL1512525.1"
                     /translation="MTNLEIEYKTLLTKDEYNRLLSQMTHVPPVTQTNYYIDTDHFDL
                     KAHKMSLRIRTFVAAPAELTLKVPEKVGNREYNLELDDTQAKAIIQTGQLPKSAILDI
                     ISTLDVDLSAIKTFGNLTTIRREADTPIGKLALDYNQYAGIKDYELELEVTDPVRGKV
                     DFDHFLAQHQITFKYSKSKVARFSKTLKKS"
     gene            40939..41610
                     /locus_tag="TV193_000286"
     CDS             40939..41610
                     /locus_tag="TV193_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEL1512526.1"
                     /translation="MALDWEEFLDPYIQTVGELKIKLRGIRKQFRKQNRYSPIEFVTG
                     RVKSVESIKEKMALRGVLEENIAQDIQDIAGLRIMVQFVDDIEDVLSLLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRHLSDGVGNSDDT
                     DELYR"
     gene            41585..42421
                     /locus_tag="TV193_000287"
     CDS             41585..42421
                     /locus_tag="TV193_000287"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEL1512527.1"
                     /translation="MTQMNYTDKVKRVAIIANGKYQSKRLASKLFGVFKDDPSFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDRVRFVGIHTGHLGFYTDYRDFEVDQLIANLR
                     RDTGEQISYPILKVVITLDDGRLFKARALNEATIKRIEKTMVADIIINNVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSVIIPKKDKIE
                     LVPKRLGVYTVSVDNKTYHLKNVVKVEYFIGNEKIHFVSSPSHTSFWERVKDAFIGDS
                     ES"
     gene            42418..43320
                     /locus_tag="TV193_000288"
     CDS             42418..43320
                     /locus_tag="TV193_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1512528.1"
                     /translation="MRFEFVATKKTKVKTLLKEHDVSKGLLAKIKYKGGNIWVNGVAQ
                     NAIYLLDIGDVVAIDIPNEESFEQLTAISHDLDIVYEDEHFLILNKPAGYASIPSAIH
                     SNTIANFIKAYYIKQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAIN
                     KRYYALVCGQERLPDQGEIIAPIGRTDDSIITRTVTPKGKYAKTSYKVIARYPENVSL
                     VDITLHTGRTHQIRVHFAHLGFPLLGDDLYGGRLDLGMTRQALHCHHLSFTHPFTESR
                     SDHTICLTDDFESVIIDLQKKDRG"
     gene            43324..44325
                     /gene="pta"
                     /locus_tag="TV193_000289"
     CDS             43324..44325
                     /gene="pta"
                     /locus_tag="TV193_000289"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEL1512529.1"
                     /translation="MSIRNLFGGLREKIVGKNMKIVFPEGNDERVVRAAARLKFEGLV
                     EPIILGQADDIRSLLTQLGFAEQHYTIINPNDYADFEKMKAAFVELRKVKATLEDADR
                     LLRDVNYFGVMLVKLGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTEQRLVFADCAINIDPTAQELAEIAVNTADTAKIFDIDPKVAMLSFSTMGSAKAPQV
                     EKVQEAVRIAKELRPELALDGELQFDAAFVPSTAAIKAPDSSVAGHANVFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQALENESIN"
     gene            44425..45183
                     /locus_tag="TV193_000290"
     CDS             44425..45183
                     /locus_tag="TV193_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1512530.1"
                     /translation="MTKIALVTGASAGFGKAIAEQLIAQNIKVIGAARRIEKLRELEG
                     IFGSERFYPLQMDVSEPTAIDKALAELPKEWQAIDILVNNAGLALGLDKAYEADVANW
                     LTMINTNIIGLIYLTRQVLPQMVSSNNGMIINIGSTAGTIPYPGANVYGASKAFVKQF
                     SLNLRADLAGTNIRVTNIEPGLCEGTEFSHVRFKGDHERVKALYAGAHAIQPRDIANT
                     VSWIIDQPEHVNINRVEMMPVSQSYGSQPVSRHD"
     gene            complement(45288..45974)
                     /locus_tag="TV193_000291"
     CDS             complement(45288..45974)
                     /locus_tag="TV193_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEL1512531.1"
                     /translation="MTKTIYTLALVDDKNNLQKTFFTTLSQEFSYLFHITIVRQLTTE
                     QLKKAQAIFTFQNLEASLPVLYFNQADKEQGFTVSDHTFTDSQQTLRLAKYLMQFYQA
                     LAPHFLTYLPLQARIADHQGQIIFDNHRFNGNFFASDKHDVIEDWILTDLHKAATGSK
                     LYLIPTASQDHIYMQQYQALYDDTKQFVGVYDMILDFKPMLQHYLEETGQAIVGWSDV
                     TSGPSLSDHF"
BASE COUNT        12979 a         8771 c        10557 g        13767 t
ORIGIN      
        1 tggagaaata gagattatag agaaatagat aattcaggaa attctatatc aattgcttga
       61 cattgtaggg aaagtcctct atcatgaatt tgctgtatcg cttttatgat gtacaatcag
      121 gcctcattac agttgatggg caaaatattc aggagtattc tagagaaagc ctgcgttcac
      181 agatgggtat tgtcttgcag gatccttatt tgtttacagg aacgattgct tctaatatca
      241 cgatgggaaa tccagcttat tcggatcagg atattttaga tgctttggaa aaggtcggag
      301 cctcttcgat gattgctcgt ctggaaaagg gcattcatga gcctgtctat gaaaaaggct
      361 cctcttattc aagtggcgag cggcagctaa ttgcttttgc taggacattg attgccgacc
      421 ctaaaatttt gatcttagat gaagcgacct cgcacattga tactgagaca gaggacatca
      481 ttcaacaggc tatggaggtc ttaaagaaag gccgaacaac ctttatcatt gcccatcgct
      541 tgtctaccat tcaatctgct aatcaaattt tagtattgga taaggggagg atcgtcgaaa
      601 gaggaacaca tcaggaattg ctagatcagc aaggcattta tgctgaaatg tccaagctac
      661 aagaaaaggt ggctgtacag taatgctttt tagtgatagc tatcaaaaaa ttccttttct
      721 aggccgtgtt aagcagcagt agtctgtgaa gtaggagcta tatttaggtt ttgtgcctaa
      781 gcctttaagg tttttaagag gctggattag ggcttaacat caataaaatc atatgtcact
      841 ttatcacagc atgttgtggt gaagtgtttt ttgtgtcgtc ctgctaaagg gaagatcctc
      901 acagtcaggg cttggctggc tcctttatca gagtcagatc attcatacgt acttcctgtc
      961 aggcttggct aagttgaatt gtatgttgag atcagcatgt cagcaattta tgctttgtgt
     1021 ctgactttta gcagcttgta catgaaatag gactaaagga cacttgaatt gatgaagaat
     1081 cagcttaaaa accatttgtc ctagatagga taagaactgt ctaaaagggg gatagatcat
     1141 cgcaattttt aacaatttag tgtaaaatag taaggtgaat gttttgatga aataaacgaa
     1201 aagatttagg atatgaataa gacaattgga tatggcaagg cacacagcaa aatcatttta
     1261 atgggtgagc attctgtggt ctatggctac cctgcgttgg ccttgccctt aaaagatatt
     1321 gaagtgacct gccggatttt ccctgctgca aagcccttag cctttgattt ttatgatccc
     1381 ttatcaacgg cagtttatgc agccttggag catttggggt gcttggcaga gcccattcat
     1441 tatgatatta tgtctcaggt accacaaaag cggggcatgg gctcctcagc agctgtttcg
     1501 attgcagctg ttcgagctgt tttttcttat tttgggcagc ccttgtcaga tgagctgttg
     1561 gaaatcttgg tgaataaggc agaaatcatt gctcacacca atcccagtgg cctagatgct
     1621 aagacctgcc tcagtgataa ggccatcaaa tttattagaa atgttggttt tgataccatt
     1681 gatattcagt taaatgctta tttggtcatt gctgatacag ggattcaggg gcatacgcgt
     1741 gaggctgtca ataaggtggc tcaatttgag gaggaaaatc ttcctcattt agccaagctt
     1801 ggctgtttca cagaggctgt tgagcaagca attaagacaa acgattgcct agctattgga
     1861 cgattcatga cgcaggcaca tgaatcacta aaggctattg gtgtcagtgt ggcaaaggct
     1921 gatcagctgg ttgcagcagc tcttgaggct ggcgctttag gagctaaaat gactggtggt
     1981 ggcttaggag gatgtatgat tgcattagct gaaaggataa cagacgctca gcaaatcagt
     2041 aagaaactaa aagaagaggg agctgtaaat acgtggattc aaatactgta acggtaactt
     2101 cctacgctaa tattgctatt gtcaaatact gggggaaaaa agatgaggct aagatgatcc
     2161 catcaacctc tagtatttct ttgaccttgg aaggcatgta cacgacaaca agtctttctt
     2221 ttttgcctgc ctcagcaaag ggagatcagt tttatatcaa tggtgttctg caggacgcca
     2281 aggagcatgc taagattact gcgattttgg atcagttccg tcagaaggac cagacttttg
     2341 tcaaggttga agccagcaac agcatgccaa ctgcggcagg cttatcctca agctctagtg
     2401 gcttatctgc tctggtaaag gcctgcaatc agctttttca agctaagcta agtcaagaag
     2461 agcttgccca aaaggctaag tttgcctctg gctctgcttc gcgttctttt tttggccctg
     2521 ttgctgcctg ggataaggat acaggctcta tttataaggt caaaacagat ttaaagctgg
     2581 ccatgattat gctggtcttg aacgatgcta gaaagcccat ttcgagtcga gaggggatga
     2641 agcgctgcag cacaacctca acaagctttg accagtggct ggcccagtca gaaagtgatt
     2701 atcaggccat gttgcgtgcc cttagtgaca atgattttga aacggttggt tggctgacag
     2761 aagcaaatgc tctagccatg cacgcaacga ccaaaacagc cagtccttcc ttctcttacc
     2821 taacagaggc ctcctatcag gccatgctaa gggtcaaaga gcttcgtcaa gagggctatt
     2881 cttgctattt tacgatggac gctggtccaa atgtcaaggt gctttgttta gaagaggact
     2941 tagagcggct gtcgcacctt tttgaaaggg agtatcgtat catcgcctca aaaacaaagg
     3001 aattaccaga tgtctaaata tcatgttcaa gcaggaggaa agctgtatct gacaggcgaa
     3061 tatgcgattc taaggccggg gcaaacggcg ttgatttgct atattcccat aatgctgaca
     3121 gctgtcattg aagcagcaga ggctgttagt atcagctcag atatgtttga ccatgctgct
     3181 gatttgtcac cggataagga ttataggctg attcaagcct ctattgaagc ctttagttta
     3241 tatatagata aggatattaa ggagctgcca gccttttctt tgtctattac tggtaagctt
     3301 gagcgtgacg gtaaaaagtt tgggattggc tctagcggta gtgttgttgt actaacgcta
     3361 agagctttgg cagcctttta tcaggttcag ctgctaccag agcagctctt taagctggct
     3421 gcttataccc tgcttaaatc aggagataat ggctccatgg gggacattgc ctgcattgcc
     3481 tatgagagct tggttgctta tacatccttt gataggcgta aggttggtca atggttgatc
     3541 gagatgaccc taaaagagct aatggcagca cattgggggt atacgattga gactattgag
     3601 cctgctctgc cctgttggtt tcttgttggc tggacccaag tcccttctat ctcaagagag
     3661 atgattcagc tggttaacaa gagcattagc tgtcagtttt tagagcaaag ccagctggtc
     3721 acacaggaag tgatgactgc cctgcagctt ggtcaaagaa aaaggctcaa agctagcatt
     3781 gaaaaagcgg gtcagttgct gcaagggttg gcttcagtta tttatcaccc taagcttacg
     3841 cagcttgtcc aggcttgtca agggcttgat gctgctgcca aatcatcagg ctcaggaggt
     3901 ggggattgtg gtattgcact cgtttttgag gctaaggaca ttgagcctat ccttgccaga
     3961 tggcagcaag cagggattgt attactatat caggaggaat ggggataaac atgactaatc
     4021 gtaaggatga ccatatcaca catgctttga gctatcattc tccttacaat gcatttgacg
     4081 acatggagct cattcactgt tccttgccga gctatgattt agctgatatt gatctctcaa
     4141 cccattttgc tggctgtgat tttgagtttc ctttttatat caatgcgatg acaggtggta
     4201 gcaagaaagg ccaagcagtc aatgaaaagc tggccaaagt ggctgcggct acaggtattt
     4261 taatggtgac aggctcttac agtgcagcct tgaaaaatcc tgaggacact tcctttcaat
     4321 tgcgaggtgt agcaccagat ttacagttgg ccaccaacat tggtcttgat aaggctgttg
     4381 acctagggat tagagctgtc gaggaaatga agcccttgtt tttacaggta catgtgaatg
     4441 ccatgcagga gctgttaatg ccagagggag agcgcagctt taagcattgg aaggatcatt
     4501 tagcggccta tgccaagcag cttccagtcc ctttgatttt aaaagaggtt ggctttggta
     4561 tggatattaa gaccatcact atagcacgtg atatgggagt aaaaaccttt gatatttcag
     4621 gaagaggagg aacctccttt gcctacatcg aaaatcaaag aggaagtaat cgctcttacc
     4681 tagacgattg gggacagaca acagtgcaat gtctattaaa cgccaaaggt ctggttgatg
     4741 aagtggagat cttagcctca ggtggtgtca gacacccctt agatatggtt aaatgcttgg
     4801 tgctgggggc acgtgctgtg ggcctatcgc gagtggtatt ggagttagtt gagacctatc
     4861 cagttgagca gatcatcgct acgatcaata gctggaagaa ggagcttaag ctcatcatgt
     4921 gtgctttaga ttgtcgaacc ttgagcgatt tgcgtcaggt ggattattta ttatatggta
     4981 ggctttatca ggcaaaccgc taaagacttt ttagccctga gctaactttc cttagaaaat
     5041 catcacagga gttaagaagc tgcctgcttg gtgctgcaag ctaattcagc tgattatggc
     5101 tcgtaagatt tttagatgtc tgaatgaaat gataggacag atgacatagt atagcgctaa
     5161 tttctagtga aaatcagtcc ttggtcaggt tactgagact gaggttaagt ttatgtttac
     5221 actaacactt aaaggatatg aaaacacttg gtagctgcca ctgaagctgt taccaagtgt
     5281 ttttagtcta tgattggctt aatcgtatgg ctgttaagag ctgtcctgcc ttttctaggt
     5341 tcattggctt atcctttagt agagccttaa ctagttgagg cacctcctgc tcactagcac
     5401 ctgctaatag agctagagac ttggcctgca gcttcatgtg accagcctgg ataccagttg
     5461 aggtcaaagc ctttagagcc gcaaaatttt gcgccagccc aactgcagtg gtgatttggg
     5521 cgagaacctt agcatttggt tgctctaaaa ggctatgagc aacactgacg gttgggttga
     5581 gaccgatcga ccctccttta ctagcaatgg gcattggcag tgttagctct ccgcataagc
     5641 tatttttaga taaatcaacg tgccagctac ttagccctct ataagagcca gtccttgcgg
     5701 cataggcatg tgctccagcc tcaatagctc tccagtcatt tccggtagct atagctaccg
     5761 catcgattcc attaaagatt cccttattat gcgttgctgc tcggtaaggg tcaatctggg
     5821 ctaatttgct tgccagctct atttttttgg ccaattgctg agcttcttcc ttatgtcgac
     5881 ttaggtatct gaggtcaacc tgacatttag cactaactaa agcttttgtt gcatagtttg
     5941 agaggatagc cattaagcat tgaccaccgc ttagggcctc caaatcaggt actaaagcct
     6001 ccatcatcgt gttaacgatg ttggctccca tagcctcttg ggtatcaacg ctcagataga
     6061 caatgaaaaa atcctcctta cgctcaacgg taaggctctt tgcgccacca ccacgcttaa
     6121 caatagaagg gtaggcattg tttgcaacgt caatcaatgt atctgcgtta gctagaatag
     6181 ccagcctagc ctgctcgtca tctttaacat cataaagagc tacctgccca agcatttgac
     6241 gactgagtac ctcagtctga aagccacctg atcgcttgat gattttggca gcaaaggaag
     6301 cagcagcaac aacagaaggc tcttcagtca caaaggggac ctgataggta tgcccattga
     6361 tcagaaaatc aggggctaga ctaaaaggca gagccagtcg accgatgaca ttttcggtca
     6421 tttgattggc aatagcaatg ggtaagagct ggtctgtctc taacagcttt tgctgctgcg
     6481 ggccaagcag ctggtcatct gcgagctgtt gaatgcgttc tgcaaggctt tttttataaa
     6541 agccggccca atttggttta gtttttgtca tcatcttgat aaattcgttg gtgttcctta
     6601 atttctttga gggcaaacct gccagttaga tatggtgaaa agctggcatt gccatcttgg
     6661 tctagtctag gctcttcata aaaaagtgct tcataatcag ccactgaaat cacctgacgt
     6721 tggtctaata gggcttgtcg attagtcagt agcatgtcct tgtaaccgtc aacaagctgc
     6781 cctgaaaaca gctcactaac agctcctgag ccatagctaa acaatccaat cctatcacca
     6841 gcccttagca cctgactatt ctctaaaagt gataataagc cgaggtagag tgagcctgtg
     6901 taaatgttgc cgatttgctt gctgtaggca atagaagctt gaaagttttc ataaagcctt
     6961 tctttgtgat catctgctag tgattttgtc atgatcttat gaagtccctt tagagcaagc
     7021 tttggaaagg ggatatgaaa acaaacagca gcaaggtctg atagctcaat accttctttt
     7081 tcttggtatt tgtcccaggt tgtttttagg gaatcaaggt attgcttggt cgaataaata
     7141 ccattgacaa atggtgttga gctgtaattt ggacgccaaa aatccatcac atcacgtgtc
     7201 tgtgcgacat tgtcatgatt taactggaga atacgaggat tagtagtaac tagcatagca
     7261 atacttccag caccttgtgt tggctctccg gcggatccaa tgccgtattt ggcgatgtca
     7321 ctggcaatga ccaagacctt ggaggctggg tgtgcagcaa catgtaattt ggcataatct
     7381 aaagcagcag tagcgctgta gcaggcttcc tttatctcaa aggagcgtgc aaagggctga
     7441 atatcaagca gctgatgaac gtaaatactg gctgcctttg attgatcaat gcttgattcg
     7501 gttgctaaaa tgaccatgtc aatgcttgct ttatcgtctt tggtaaggat ttggtcagca
     7561 gctgatgcag caagcgttac aatatcctct gtaacaggtg caatgcttag agcgtcaagc
     7621 attagcccct gatgaaattt tgctggatca gtgctgcgag caagtgccag gtcttccatt
     7681 tttaagacgt attgactggt cgcaaagcca atcttatcaa ttccgatgtt cataaatatc
     7741 cttcttttat ccattttata gtcctatcca ttttatcata ttttcttaga aaattagctg
     7801 atttaatacg atagttttac ctttcaaacc aaaaacagca gcatatagct ttcttctggt
     7861 atttttgaag gaaattagat aaaataatat ggactgtgct tacagaaagg ggtttccatg
     7921 acaaaagcag atcatatttt taaagctaat atcaaaaaaa ttatggagga gggagtcttt
     7981 agcgagcagg ctcgcccaag gtacaaaaat ggtcaaacag ccaattccaa atacattaca
     8041 ggtgcttttg cagagtatga tttgtctaag ggagagtttc ctattacaac tctaagatca
     8101 atccctatca agtcagctat taaagagtta ttttggattt atcaggacca atcaaacagc
     8161 cttgatgttt tagaaaacaa atacaacgtt cactattgga atgagtggga ggtcggtcag
     8221 acaagaacca tcggtcagcg ctacggtgca atcgttaaaa agcatgatat catctcaaaa
     8281 atcctcaagc agctagagga caacccttgg aatcgccgaa atgtgatttc tctgtgggat
     8341 tacgaagcct ttgaagaatc agaaggactg ctaccatgtg cctttcaggt gatgtttgat
     8401 gttaggcgag tagatggtga gctgtattta gatgccacgc tgacccagcg ctcaaatgat
     8461 atgctagtgg ctcatcatat caatgccatg caatatgttg ccctgcagct aatgattgcc
     8521 aagcattttg gctggaaggc tggtaagttc ttttattttg tcaataattt gcacatctat
     8581 gacaaccaat ttgcgcaagc caaggagcta ttggagcgtc agccagcagc ctgtcagccc
     8641 aagcttttgc tgcatgttcc tgatgggaca gacttttttg atataagacc agaggatttt
     8701 gagctacagg attattaccc agtgaagcct cagctcacct ttgacttggc gatttaagcg
     8761 aaaaagacga ttttttctga gcattttgcc aagaaatttg atagaataaa agaagttcat
     8821 attgaggaaa gctagtgatg acaaagaaga ttattgctat ttgggcagag gatgaagcag
     8881 gacttatcgg agcgtgtggc aggcttcctt ggtacctacc aaaagagttg cagcatttca
     8941 aggaaacaac attgaatcaa gctatcctga tgggacgagt aacctttgag ggcatgaagg
     9001 gtcgtttgct gccaaatcgc caaacgcttg ttatgaccag agacagttat tatcatgtgg
     9061 agggcgcttt aaccataacc agtgtgcagg aggctttgga ttggtatcat gcgcaggata
     9121 agaccttata tgtgattggt ggcagcaagg ttttagaggc ctttgatggt tattttgatg
     9181 tcatcatcaa aacagtggta catcaccagt ttgagggtga tacctaccga cctaggttag
     9241 agctgagtga ttttgtagag gagacctctg tattgtaccc aagggacgat aacaatcctt
     9301 acgatttcac tgttacagta ttgagacatc gctaatatag ggagatgata gtctatgcag
     9361 cgtagtattt ttggggtatt tacggccttt ttgtgtgcga tttgtgtttt atgtgccata
     9421 ccggccttta gaaaaaatcg ctatggctta ggattacttt ttttattaaa tgcctttact
     9481 aacctagtga ataccataca tgccttttat ggaacactgt tttaagccta agagaatgaa
     9541 aagagaaaga tagaggaatc atggcaggaa atcgtagtaa cgatattaag gttcattgct
     9601 cgttttgcgg caagagccaa gacgaagtga aaaaaattat tgcaggtaat aacgtcttta
     9661 tttgtaacga atgtgttgcc ttatcacaag aaatcatcaa ggaagaattg gcagaagagg
     9721 ttctcgctga tctgactgag gtaccaaagc caaaagagct gcttgagatt ttaaatcaat
     9781 acgtcattgg gcaggagcgt gctaagagag ccttatcagt tgcagtttac aaccactaca
     9841 agaggatttc atttactgag agtcgtgatg atgatgatgt ggatttgcag aagtccaata
     9901 ttctgatgat tggaccaaca ggctcaggaa agaccttttt ggcacagacc ctggctaaga
     9961 gtctgaatgt tccgtttgct attgctgatg caacctcttt gactgaggca ggctatgtcg
    10021 gagaagatgt ggaaaatatc ctcctgaaat taattcaagc cgctgattac aatgttgagc
    10081 gtgcagagcg cggcattatt tatgttgacg aaattgataa aatcgctaaa aaaggtgaga
    10141 atgtctctat cactcgtgac gtatcaggag aaggtgtcca acaagccttg ctaaaaatca
    10201 ttgaaggaac ggttgctagt gttccaccgc aaggtggtcg taagcaccca aaccaagaga
    10261 tggtacagat tgataccaaa aatatcttgt ttatcgtcgg aggcgccttt gatggtatcg
    10321 aagaaattgt caagcagcgc ttgggagaaa agatcattgg ctttgggcaa aatagtcgaa
    10381 agattgatga caatgcttcc tatatgcagg agatcattgc tgaggatatt caaaaatttg
    10441 gtctgattcc cgaatttatt ggacgcttgc ctgttgtggc agcgcttgag cagcttaata
    10501 ctgaggattt gattcgtatt ttaacagagc ctagaaatgc ccttgtgaag caatatcaag
    10561 ccttattgtc atatgatggc gtagagcttg agtttgaaaa gggggctctg gaggctattg
    10621 caggtagggc tattgagcgc aagactggtg cgcgtggtct gaggtctatt attgaagaaa
    10681 ccatgctgga tatcatgttt gaggtgccaa gccaagagga agtaatcaag gtacgcatta
    10741 ctaaggaagc tgtcgaaggt caatcaaagc ctattttaga gatagcctaa ggaggtatga
    10801 tgtctgaaga gcaaatcctt aacacgcata atgcttcgat attgcttagt gcggcaaata
    10861 agtctcatta cccacaagac gaccttcctg agattgcttt ggcaggtcgg tcaaatgttg
    10921 gaaaatcaag ctttatcaat actatactag gacgtaaaag ccttgctaga acctcaagca
    10981 aacctggtaa aactcagctt cttaattttt ttaacgttga tgataagcta aggcttgttg
    11041 acgttcctgg ctatggttat gctaaggtat ctaaggcaga gcgggctaga tggggaaaga
    11101 tgatcgaaga gtacctgacc acacgacaaa atctcagagc agttgttagt ctggttgatt
    11161 ttcgccatga gtcatcacag gacgacattc agatgtatga gtttttgaag tattatgaga
    11221 ttccggtgat tattgtggct acaaaggcag acaaggttcc tcgtggtcgc tggaataagc
    11281 atgagtctat ggttaaaaag tccttaaact ttgatcaaac agatgcgttt attatttttt
    11341 catctgttga gcgtatcggt attgatgagt cttgggatac cattttagag tatttataag
    11401 catatggtaa aaaatttaag tatcttttag acaggcactt gtgtctggtc tgagaggtgc
    11461 ttttttattg acaaaaaaac aatttgttga tgacgagctt gtgttcaaaa atgtcagttt
    11521 gctaaaaaat gatgataaca aacaagactt ttatgatata atgcttagca ggataatatg
    11581 gagacatgag aaaaaggtca gagacagcta atttgctatc cctgattata actatgatga
    11641 ccagcattat tataatactc atggtgctag ctattagtag cagcacctaa cctatagtgt
    11701 tgctttttag gttacaagca ctggcgctag gagtattata atatatttag aaaggttttt
    11761 ttatgacaat aaaaaaatgc cctcaaatac ttgccttatt ccttgctttt gcagcgctag
    11821 ctagtcaggg gcaaaccgtc catgctctgg agcggcagga gacatctgtc aagcaagctc
    11881 atgaatcaga tgattggttt gatgaggacg aaggagttag cgatatcaag tctaataccc
    11941 ctacagagat agactcaaca gtaacagagt tatttggtga tgctgagcct aagactaagg
    12001 ctgaaaaaga agagtcaaaa gctccaagcc ctaagcaaga agcactgcca gcagagtctc
    12061 aaaaagaaaa agagacatct gctaaatcga ctgaccatgc gacagtacaa gcagaagagg
    12121 cacagcctga gcaaggctca gatagtcctt ggctagcaga tgactttgtt actaagggag
    12181 ataccttggt tgggctatct aaggcaggtc ttgctaagtt atcaaagaca cctgtcttgg
    12241 tactaccaag gatagggatt gacaagacag tgttgacaag gattgctagc tttgccttta
    12301 ctccaaataa atcagtcgct attgctgatt atacaggtag agcaggtgaa catggcgaga
    12361 tcaatcatct ggacgtcgaa ggcagagata tccttactga gggagaggat tttggtgcct
    12421 atgcgattaa aaagcttgtg attcctgaag gctatctttt tatcggtcaa gatgccttta
    12481 atgacaataa acagctagaa gaaatcagtc tacctgatag cttactcagt atttcagact
    12541 atgcctttgc tcacatgagt ttatctaagc ttaagctgcc aaaaagccta cagtccattg
    12601 gagatcaagc cttttttgat aatcggattg caggcacttt ggtattgcca aaagctctaa
    12661 agcagctggg agaacgcgtc tttaagtcca atcgcctcac tggacttgtc tttgagggag
    12721 aaggcttgtc tgtcctaaaa gaagcagcct ttcaagacaa tgctttcatt agtcttgtta
    12781 tcccagatag cattcaagcc ttagaagagg acgtctttac aggaaacctt ggcgatgaag
    12841 aatacggtaa tcatgccgtt ttacgaacca aaaatggtca gaatccttac agacttcaca
    12901 gtgccaatgt tcttgtcaat ccaagtgatc aggctagaac accacagcca ccaattgatt
    12961 acaacaggtg gcttgcagaa gattttacct atactggaca gacgataacc ggtttttcag
    13021 ctagtggact gcgcaaggtc aaacgcaata agcatttggt tctgcctaag aattatcagg
    13081 gtcagccctt gacagccatt gcagataatg cctttagaaa tgtcaatttt catgataaaa
    13141 ccttgcgtaa atacgaccta gaaagcgtga cgttaccatc taccattcaa aagattggtg
    13201 cctttgcctt tcagtcaaat aatctagaaa gctttgaggc cagcgaggac ttggttgaga
    13261 ttggtcaagg agcctttatg aataatcgca ttgagattct ggccttgaat gataagctga
    13321 aggtcattgg agatgcggcc tttcatatca atcggattta tgctattgtt atccctgagt
    13381 cggtcgaagt aattggcatt tctgccttta ggcaaaatgg tgctaaacat gtgatgttta
    13441 tgggagataa gctaataagt attggagaaa tggctttttt gagcaatact ctggaggaag
    13501 tggatttgag cagcttagca gggcttaaga ccatcgctgt tcaagccttt gcagacaatc
    13561 acttgagaga gcttaagctg ccagatagtt tgatgcgtat tgaagcagaa gcttttaaaa
    13621 ttaatagact tcaaagagtg accgttccag acactgtcat tagcattagc tttaatgcct
    13681 ttgatcataa tagtgatgac aaggttgtcc taaggaccac caatcacaat aaaaacctgc
    13741 tagctgatgg aaatggcttt attgtggatc cagacctatt aagtgcggat caatcgactg
    13801 ttcaagcagt tttagaggac ctgcggcgct tagatctagc tagtctacgt gctgatacag
    13861 cagctcattt tatgacactc atcacaagag gtaagcagct actaaaagaa tccgctgtac
    13921 ggttaggtta tcagcttagg ttccttgcag agtcacgatt tttcttaggg cgcgtgagac
    13981 tggatcagct gattaaaact gctgacataa ccctatctag ccatcaagac acacctaatg
    14041 ctaagctgtt gatggctaag ctagacaagg ccaagctgca ttacaataat agcgcaatga
    14101 ctgctccaaa agtaagtcgc ttggaaaaag agctcagcct gttaattgat cttgtccaag
    14161 gggtaggcgc tatctctaaa gcaacaatga ctcaaggtgt ctataagctt cagacaaccc
    14221 tacctattcc agagtattat attggggtta atctttatac tgatgatcag gggaatattt
    14281 tatttgtgct tgacatgagt gatacgattg ggcagggaca acttgatgac tatggcaatc
    14341 ctattttaaa tgttgatgag gataatgaag gctaccatgc tttggccatt gagtccttag
    14401 cagattacga aggccttacg attaaggata tattgaccaa ggagctaaat caattgccta
    14461 ttcgcgatgt caagcaagca agagagcatc gtgttggtct ttttatggca atcagagatg
    14521 ctgcaaggga agctcagctt ctactagaaa agcagagcaa agccttatca gaatcagccg
    14581 gcaaatctaa tggctcaaaa gtagctgact caggacttga gccttctgtg acactatcaa
    14641 ccaataagac taagctgcta ccaaaaacag gagccttcaa agaagcttgg gtgacaatga
    14701 tcggaatgct tgttcttttg gcggctaccc tacttaaagg cgatagtcgc tacaaaaaga
    14761 agtaaatagg cttgcttagc aagcacactc tagcaccagt aaggcttgag gggcttacaa
    14821 agcctatcta atctagcaat agtatattgc cagtgtgagc tggtgcttga gcttcaaaaa
    14881 aacaaaagag cctgaaatga cttttactag catttcaggc tctttttagc ttgtgattct
    14941 tttttgtgtg aagcttactt ctcacttatc gtaatagtat cttgatcaag gcttgctaat
    15001 aggtgtttag cagtcgggtg atccaggtag taatccgtaa tgcggtcacg aatttcttgt
    15061 tcgatgacac gtctaagtgg acgaactccc atcgcatgat catagcccag atcaatcaaa
    15121 cgctctttaa catcgtcagt cacctcaagg ctaatgcctt ttttagcaag ggtttggttc
    15181 acttctgtta gcattaaagc aacaatttct tgtaaatcct ttttcgctaa atggttgaat
    15241 tcgatgacac cgttgaagcg attcaagaat tctggtctaa agtaaggtgc aatacgctcc
    15301 atgatagcag gctcttgatc agcacgatct cctgcttgat ggccaaaacc agcattagag
    15361 gttgcgatga taaccgtatt tttgaaattg atcgtgttgc cttgtccatc tgtcaatcgc
    15421 ccatcatcaa gcacttgaag aagcagtgta atgacctgtg ggtctgcttt ttcgatttca
    15481 tcaagcaaga tgatagagta aggactgcga cggacacgtt ctgtaagggt attttgatta
    15541 tcatcatagc caacatagcc agctgttgtt ccgattaatt tggaaacagc tgtgcggtca
    15601 ctatattcag acatatctaa gcgaatgata gcgtcctttg agccgaacat atcaagggct
    15661 aactgcttag ccagctcggt cttaccaaca ccagttggac caacaaagag gaaggagcca
    15721 attgggcgat taccgtcatc aaagcctgcg cggttgcgtc gaatcgcacg agcaacagcc
    15781 tcaactgcac catcttgtcc gataacatgg cctttaagac ggttactgat ttccttgagc
    15841 ctttctaaat cactagcccc catatttgat actggaacac cagttagacg ttcaacagat
    15901 tctgcaatat cattaacagt ggcagtgacc ttttgccctt cactgtgatg attgatttgc
    15961 ttttggagct cctcaatgcg ggtcttagca gttaaggcct tttcaaagtc ttcttctgca
    16021 acagcctttt cctgtagctc cttttgctta gtgatttctg cttcaagtga ttttagatca
    16081 gtgacagggt gctgagctgc tagatgagca gcagtcatat caacaaggtc aatggcttta
    16141 tctggtaggc ttcgttgtgg aatatattgg atagcataat caatagctgc cttcaagaca
    16201 gagtctggta ggatcacatt gtggtgctgc tcgtagaggt tgcgaatgcc cattaaaatg
    16261 tggaaggtat cctctgctga aggagcatta accttaacct cgttgaaacg acgagcaaga
    16321 gcagcatttt ttagaatggt gttgcgatac tcatcttgag ttgtggcacc aatcagggtc
    16381 aactcaccgc gtgagagggc tggttttaga atatcagcta agcccttaga gcctgagtct
    16441 gaaccagctg accctgcacc aaggatttga tggatttcgt caaagaagag aatgatattg
    16501 ccagcctcct taacctcttt aaccatgttt tgaatgtttt cttcaaagga gccacgatac
    16561 tgtgtgccag cctcaaggcc agaaatatca attgagataa tctctttatt tttgatggca
    16621 gctggcacat caccgttgac aatagcctgg gctaggcctt cgacaacagc agttttacca
    16681 acaccagcgt caccgacaag aacagggtta ttcttggttc gtcttgctag aatttctgcg
    16741 gtcgcttgaa tctcatcgtt tcgtccgatc acaggatcta acctgccttg ccgagcttct
    16801 tcggtcaggt ttgttccgag cttggttaga atgccgtctt ttttaaggct gctagcctgt
    16861 ttttcttgtc cctcagctgc agctagctta ccggttttcc ggtattcttg aaattcctct
    16921 ggtgtcatct cacgtccatt gacaagatag cgacgatttt cgctgcggta gccgccgatg
    16981 tttcccatta actgattgaa aatatcgtcc atattttcaa aggggtcttt tccataatag
    17041 gttgccatat acacttacct cacttgtatt atatttacca gtcattatga gctactggta
    17101 taggtagaag gtgatcggtg ttggctcata cagagatcat agagaggtct tatgagagtc
    17161 tattgctcag gcttattact caccttctaa taatattata tccaaaaggt cagtaaaggt
    17221 caaacaaaaa gtatgaataa ttaaccttta taatcaggtg cttatagccc ttgaaacatc
    17281 agatgactat gccataagct gctggtgctt ttttgctagc aaggctatct gtaaagaaga
    17341 gacttttgtc aaaaatggtt ttactttttg ttctaaaggc tttcatgata taataaaaga
    17401 aaagcacaga ggtcaattat ggaacaaaca ttttttatgg tgaagcctga tggtgtgaaa
    17461 cgtggcttgg ttggagagat tctacgccgg attgagcgtc gtggctttac ctttgatagg
    17521 cttgaattgc gacaagcaac cccagaattg ctagctaagc attatgacac cttaatcaat
    17581 aagccctttt atccagagct agaggcctat atgacaagcg gacctgtttt aatcggcatt
    17641 atctccggta atcgtgtggt ctcttcctgg cgaaccatga tgggggtaac caatcctaaa
    17701 gacgctttac cggggactat tcgtggtgat tttgctcaag cccctggtga tgatggcggc
    17761 attttcaacg tggtgcatgg ttcggattcg agagattcag ccaagcgaga aattgcgatc
    17821 tggtttggac atagctgaca ttgggcttgg gcctattctt ttaagaactg ataaagcaat
    17881 tgcataagga gttgataagc ccatcatcaa tagtagctca gcattagaag ggtaacagcc
    17941 ttgatgttgg gctatttttt tgcttgccta gggtctgtat gcttgtcctg atgagcaggt
    18001 agacaaagca gcataagttt aacaatcctt tgcggcagtg atcaattgta gctctaacca
    18061 tagcatcagc tatttgaaag ccttgaaaaa gaaagctaag gctaacaagc tagtctaggt
    18121 catttactac aagcgacttt tttcaattag ctgctcaagg caagtattga aaaaagtcca
    18181 tttttcatgt catttgtaat aatatggtat atttttaacg aaaagtcgtt ttagttgaga
    18241 aaatatacaa aaaaggctat gatatagtta ataaagttgt tataccccct gtgtcttgta
    18301 cactatgact tgtagagagt ttatcaaagg aggataagat gaacaaacaa agcatgaccc
    18361 atttttctaa gaagctgatg aagttagccc ttttaggttt ggcattgcca ttaagcttgg
    18421 tgtcggtggt agatactccg gttcttaacc aatccgaaaa agctgtttat gccaatgatt
    18481 ttggatctgg aaatcgagcc agtgattatg taccggcggc taacgcttgg agctttgagg
    18541 cttatccaga ttactacagt attttaggag ctagtcatct taatcctgct gtctttccag
    18601 agcctagtaa gatgtcatac agtcctttag acgagttggg ccgcacacag gtcgcaagag
    18661 gaacaataac ctatcacaat atcgtgatga attacaatgt tcggcaacgc tttgctaaaa
    18721 atcagaaccc ttcaggctgg attggtaacc ctagaaatgt tcgctacact attgagtggc
    18781 tagatggact atcctatcag ggagattttt ggaatcggag tcatttgatt gcagatagcc
    18841 ttggtggagc agccttacgt gtcaatgcta ttactggtac aagaacacaa aatgttggcg
    18901 gcagaaatca aagaggcggt atgcgctata ttgagcaaaa ggtgcagcag tggattgagc
    18961 agcatacaag cgcagttgtt tattacgaag cggtgccaat ttaccaggca aatgagctag
    19021 ttccaagagc tgttgttgtt tcagcattgt catcagacgg aggtcttgac gaaaaggtca
    19081 tggtctataa taccgccaac ggctatacca ttgattatgc cactggcgca ttccgcagta
    19141 actaggcttt tgtactaagc tgtagctgat caaggtctga ctaagacaag ctcatcagca
    19201 attggtatat aaaaagacgt ggcaacaaca tgttttaaat gagttgtcat gtctttttag
    19261 tgtcgtcagc ttttcacatt gtcttagaat gatcacacct agctagccgc taaaagcatt
    19321 ggtccaaaga aatgttaaga atagatagaa tgccttttaa tcagtggtat gggactgcta
    19381 gctaatataa tgcctgcagt tgagccaatt tctcatctag gctaataact aacaagctat
    19441 tgacttatcg tgttcattag aatgtcagct gttgtagttg gtagtattcg aatacgatta
    19501 agcgatagca ggccattagc agcacttgct agtccttcat ttgttgtgac ccctaatttg
    19561 taatgcagat cctcagcaat ctttaatgtg gtatcagtat aacgacctgc tggataggca
    19621 attgcaatgg tatcttggtg tagctctcta tctaggtatt ctttagaatc tttcatttca
    19681 gcggtttgac tagcagcgct tgcctgagat agatcagggt ggttaaccgt atgatcttgg
    19741 aaagacatgc ctgcctgctt catttccttc atctgatcca atgtaagatt ggccgcatta
    19801 cctgcctctg taaagccagt gataacgtta ttggtggcct tgatgtcata ctttttcagg
    19861 attggaaaag caacgttgta aaaatcaacc atgctatcat caaaggttag ccagacaacc
    19921 ttttcagcag gaagctcgtt agctgataag actcggtagg cttcttcggg agataaaaag
    19981 tagtagccgg cctccttcat tgcctttagc tggctttcaa aaagatctgg agcaacgatg
    20041 agattggcac ttgctgcctc ttctggtgcc ataacgtgaa tagcatgata cattaagata
    20101 ggaagcttaa cagggttttg ctgcttggtc cagctgacag ctcctttttg ctgctgacta
    20161 tttgtatggc tagcttcctt attagttgct tttttgctag gcttgggagc tggtttttta
    20221 tcagtttttg aaaataggct tattttgggg attgcctgcg ataattgaga gatgcttatc
    20281 tttgaatggc tcttgtaaag gtagacaata gctgataagc ctatgataca ggcaagtagt
    20341 agcatgagat taatcatttt gaagattttt cttttcttac gccgtttgtt tctgttgttc
    20401 atcacttgct ccttgtttat tgattagtct attgtaacat ttttttaagt aagctgtctt
    20461 tcgttaactt aattttttgc taacattcta ttagtgttat gctttgtaaa acaagaccta
    20521 gatttgctat aataagacag agtatttaag acagtcaaaa aaaggaggat aggatgtcag
    20581 ttaaggttgc attattaggc tttgggactg ttgctagtgg cattcccttg ctattagaaa
    20641 acaatagtag caagattcgt gcagtggtag gtgatgattt ggtgattgca aaggttctgg
    20701 ttagagatga gaccactaag aagcgtttgt tggatcaagg ctattcctac caatttgtga
    20761 cctccattga tgatattgtt gatgatgaga gcattgatat ggtggtcgaa ttaatgggtc
    20821 gtatcgagcc tgcaaagacc tttatctcgc gtgctctatc agccggaaag cctgttgtga
    20881 ctgctaataa ggatttgata gccttgtacg gaggagagct ctcgactttg gcagctaagc
    20941 atcaggtagc tttgtactac gaggctgctg ttgctggtgg tattccaata ctaagagctt
    21001 tggctgattc ctttgcctca gataagctga cgcgtctgct cggtgtgctc aatggaacaa
    21061 ctaatttcat gttaaccaag atgattgatg agggctggac ctatgaaagg gccctgcaaa
    21121 aagcgcagga gctgggctat gctgaaagtg atccgactaa tgatgtgaaa gggatcgatg
    21181 cagcttacaa ggttgctatt cttagtcagt ttgcttttgg aatgaccatt gactttgagg
    21241 ctattagcta ttcagggatt gataaggttc gagtagaaga tgtgacagta gcgcagaagc
    21301 tgggctatgt gatcaaatta gttggtctac ttgaagagac ggcttctggg cttaacgcag
    21361 aggtatcccc agtcttttta ccaaagacac acccgttggc tgctgtagac ggtgtgatga
    21421 atgctgttta tatcgagtca attggggttg ggcaggctat gttttatggt ccaggtgccg
    21481 gtcaaatgcc aacagctaca gctgttgtgg cagatatgat tcagactgcc tgcaccttac
    21541 gtgaccatac agtctcagtc tttaatcgtt ttgctacaaa aactagacta gctaagtctg
    21601 aggatattat gagtccctat tactttgcta ttcaagcaac taataagttt ggtcagctac
    21661 tagagctaac aaggctatgt gatgtttgtg gcattagagt tgagcagctg ttatcagatg
    21721 agatagatag tgacaggtta gactttgtga tgattactca tgagatgagc aaaaaggagc
    21781 ttgcttgctt tacagcgcta ctacaggatc atcaggattt ccgtatgtta agtacattta
    21841 agattttagg agattgacat gaagatacgc gtacctgcaa cctcggctaa tttgggacct
    21901 ggatttgact caatggggat tgctgtttca aaatacctag aagttgacat tttagaagaa
    21961 cgtgaccaat ggtttattga gcatgatttg ggtgatattc caaatgatga tagcaactta
    22021 cttatccaaa cagcccttag gctagcacca aatattccag cacatcgtct aaagatgacg
    22081 tctgatattc cattggcacg tggcttggga tcgtcctcct cggtgattgt cgctggtatt
    22141 gaattagcta atcagctagg gcatttaaac ctaacagacg accgtaaatt ggccatagca
    22201 actcgtattg aggggcaccc tgataatgta gctccagcga tttttggtca attggtaatt
    22261 gcttcacaga ttggtaagga cgtggattac atcattgcgc cttttcctga cctttctttg
    22321 gtttgtttta ttcctgatta tgagctgaaa acctctgatt ccagagatgt attgcccaag
    22381 cagctatcgt ataagcaggc agtggctgct tcctcagttg ctaatcttgc tatagctgcg
    22441 ctattgaccg gtaatttgaa aaaggccggt cgggcgattg aaaatgacca attccacgaa
    22501 atctaccggc aaagattagt cagagagttc cagccgatta agcgagctgc agcagctaat
    22561 ggtgcttatg caacctactt atccggtgca gggcctgcta ttatggttat gtgtcccaat
    22621 aagaaaaaaa tggcgattta tgaggccatc gagcagctag gtctaattgg tcagttggtg
    22681 tctctagagc tggatcgtca ggggctgtgt cttgtctaga ctggcaaggt actggtatgc
    22741 ttgcctagta ggcttattgt tgatatcaga tggacttaaa gcttagtcat tcaaatacat
    22801 caaaaaagtg aggcttgatc gttttatcgg ctttcacttt tttcttgata tgttatacta
    22861 gagtagactt tgtgaggtgt gtgatgaatt atcaagaaac attagactgg attcatggtc
    22921 aggaaagatt tgggatcaag ccaggtgtaa aacgcatgcg ttgggtgctt gagcagctag
    22981 gtaatcctca agataggatt agaggaatcc atgtggtcgg cacaaatggt aagggatcga
    23041 cggtcaatga cctacagcat atttttacta gagcaggcta tgaggttgga acctttacct
    23101 cgccttatat catggatttt aaggaacgta tctgtctcaa tggtgagatg atctcagaga
    23161 ctgaccttgt taaggctgct aattgtattc gtccactaac ggatcgcctt atcagtgaga
    23221 caagtttggg tcctgcaaca gtctttgagc tgatcactct gatcatgttt ctttattttg
    23281 gtgagagtca cccggttgat attgctatta tcgaggcagg attagggggg ctttatgact
    23341 ccactaatgt gtttcaggcg atggctgtgg tttgcccgtc tattggtctt gatcatcaag
    23401 ctattttagg tgatacctat gctgacattg cctatcaaaa agccggtgtg ctaaagggtg
    23461 gtgaagacct tatttttgcc attgataaca aagaggccag acaggttttt ctaaaaaaag
    23521 cagagcagct tggcgtgcct atttgggaat ggcgtcgaca gttcaacatg ctacagggtg
    23581 aaggtggtta tcaatttaac agtcagcttg gtcagctgtc tcatctagtg cttgcaatgc
    23641 ctggtcagca tcaggtagcc aatgcaggcc tagccactat gacaagcttg atattacagg
    23701 atcggtaccc aaaggtaact gagtctgtta ttagagaggc tctggcaagc agcttttggt
    23761 tgggacgaac agaattgttg gcacccaacc tgatgattga tggtgctcat aataatgaaa
    23821 gcattgccgc cctgattgat gtgatatcat cagactatca ggataagcag attcatattc
    23881 tatttggtgc cattgatacc aagcctgtct cagatatgct gcagagtctg gagcgtcttg
    23941 gagatgtgca agtaacaagc tttcactatc ccaatgccta tcctttggag gcttatccag
    24001 ataggctaac aaaagtagca gattttagag catttttaga ccggcttgag caagcagctg
    24061 ctgatgattt tttcctgatt acaggctctc tttacttcat ctcagaggtc aggcagtatt
    24121 ggaaaaaggt attaagcaag taatgctttc tcacatcaac tcatcaaaca agattaatca
    24181 actaaaaagg ggaaaaccat tgccaatcaa tcaaaaaaaa gcagaagccg ctatctatca
    24241 attattagaa gctatcggtg aggatccaaa ccgagaaggg ctacgagata ccccaaagcg
    24301 tgttgccaag atgtatctag aaatgctctc agggctggaa caggacgcta aggatgaatt
    24361 tacagctgtt tttacagagc atcacgacga tttggtgatt gttaaggata ttagctttta
    24421 ttccatgtgt gagcaccatc tggtgccatt ttatggtaag gcgcatattg cttatttgcc
    24481 tagtgatggg cgtgtgacag gcttgagtaa gctggcaagg gcagttgagg tgacgagcaa
    24541 aagacctcag ctgcaggagc gtttgacagc tcagattgct aatgctcttg ttgatgcctt
    24601 gcagcccaaa ggggtttttg ttatggtaga agcagagcat atgtgcatga ccatgcgagg
    24661 tgtcaaaaag ccaggcagta agaccattac gacaactgct agagggattt acaaggatag
    24721 tagagacgac aggcgtgagg ttatgcaatt aatcatggag ggctagggta tttatgacta
    24781 ttggacatta ttcagccgct ggtgaggcag ctattatggg gattttaaat gtgactccgg
    24841 attcgttttc agatggtggc tcctatacta gtgttaatca ggccttggca caggccgaaa
    24901 aaatgctgtc agaaggagcg actgtcattg atattggagg cgagtcaaca cgaccgggct
    24961 gccaatttgt gccggcagaa gaagagattg cacgcgttgt tccaatcata aaggccatta
    25021 aaaaacggta tgatgtcctt attagcattg atacctacaa gacagaaact gctagagcgg
    25081 cccttgaagc aggagcagat atgctcaatg atgtctgggc aggactatat gacggtcaaa
    25141 tgctaagtct agccgccgaa tacgacgttc ccattatatt aatgcataat caaaccaaag
    25201 aggcttatgc tgatgttaca aaagaggttt gcagcttttt acaggctaga gcagctgcag
    25261 ccctcaaagc aggtgtcaaa aaagaacata tctggcttga tccaggattt ggctttgcta
    25321 aaaatgttga gcaaaatata gccttattaa aagggctaaa tgaggtttgc cagttgggct
    25381 atcctgttct ttttgggatt tccagaaagc gtgttgtaga cgccctactt ggtggcggca
    25441 ctaaagccaa ggatcgtgac ggggctactg ccgccctatc agcctacgct attaataagg
    25501 ggtgtcaaat ggtgcgcgtg cataatgtcg gtgctaacag ggatattgtc tctgtattga
    25561 gtcaattaag gtgagaaatg atggataaaa tcagattaga ggcttgtcgc ttttatggtt
    25621 atcatggtgc ctttaaggag gagcaggtct taggtcaaat ttttgtagtg gatttagaat
    25681 tatcagttga cttgatggct gcctctcttt cagactgcct agaggatact gttcattatg
    25741 gtttagtttt tgaaacagtc cgtcaaattg ttgaggaaaa gacctttacg cttatcgaac
    25801 gtttggctgg tgccatttgt caagagctat ttgcccagtt tttgcctatt aaagcgatta
    25861 aaatcgctat taaaaaagaa aatccaccga ttgcaggcca ttatcaagct gtcggtattg
    25921 aattggagag aaagagatga cacttgttta tttaggcttg ggaactaata tgggagatag
    25981 ggcaggctac ctacaggcag cagttaatgc cctatctaag ctgccagaga ctgagttact
    26041 gagacaatcc tctatctatc aaacagcagc ctggggaaaa acagatcaaa atgccttttt
    26101 gaatatggct tgccagctag atactaggct gacatcagaa gctcttttgg cagctacgca
    26161 ggctatcgag caggctctgg gacgagttcg tcatgaaaaa tggggcccaa ggacaattga
    26221 tattgacctc ttgctgtttg gtgatgagcc gtatcaatca gagaccttgg ttattcctca
    26281 cccttacatg acacaaagag cctttgtttt gattccttta ttagagattg cacccgatgt
    26341 gaccttacct ggtagccaga aaagcctgag gtcttacctt gatgctttag agcaatcaga
    26401 tgtagccttg tggtcacatg agtattcaaa taagttttct taaactgtcg ttatttttac
    26461 taaaatttga tataatagtg ctactctttg ctgatttttt gtcttatatt aagaaatgat
    26521 tgaagaaaga agaagattat gatagctgaa cttgaaggca ttgatattcg agagaatgaa
    26581 gccttaaaac attacaccta tacccaagta ggcggtccag cagatttctt ggcttttcct
    26641 agaaatcatt acgaactatc ccgtattgtt gattatgcca atcataatca tattccttgg
    26701 atggtccttg gaaatgccag taatctcatt gttcgagacg gtggtattcg tggctttgtt
    26761 atcatgtttg ataagctcaa cgccgtccgc cttaatggtt ataccttgga ggcagaggca
    26821 ggcgctaacc tcattgaaac aacaaaagtt gccaaatttc atagcttaac aggctttgaa
    26881 tttgcttgtg gcattcctgg aagcataggg ggtgctgttt ttatgaatgc aggtgcttat
    26941 ggtggagaga ttgctcatat ttttttgtcg gccaaggtct tgacaccaga agggaaaata
    27001 aaaaagatct cagccagaga gatggccttt ggctatcgtc actctgtcat tcaagaaact
    27061 ggtgatattg tgatttcagc caagtttgct ttaaaaccgg gtaatcatga cagtatttgt
    27121 caggagatga atcgcctcaa ccaccttcga aagctcaagc agcccttaga atttccctct
    27181 tgtgggtccg tttttaagcg tcctcctggg cattttgcag ggcaattgat tatggacgct
    27241 aacctaaaag ggcatcgtgt tggcggtgtt gaggtctcta aaaagcatgc aggctttatg
    27301 attaatgttg ctgatggctc tgccaaggat tatgaggact taattgctca tgtcattagg
    27361 acagttgagc aggcatctgg cgttaggctt gagccggagg ttcgtattat tggtgaaagc
    27421 ctttaatgat tgtgttatca aaaaagaaaa attgtggagg atttatgaca attgactaag
    27481 ccaattatca catttgacaa tgtctcaaag acatttgagg acagcgggac acaggtccta
    27541 aagaacatta attttgagct tgaggaggga aaattttaca ccctgcttgg tgcctcagga
    27601 tctgggaaat caaccatttt aaatattatg gctgggctgc ttgatgcgac cagtggtgat
    27661 atttatttag atggtgagcg tatcaatgat ttgccgacca ataagcgtga tattcacact
    27721 gtttttcaga attatgcttt gtttcctcat atgacggttt ttgagaacgt tgcctttgct
    27781 ttaaagctga aaaaggttga caaacaggag atagcaagac gtgtcaagga aaccttaaaa
    27841 atggttcagc tggagggcta cgaaaagcga tccattcaaa agctttccgg tggtcagcgt
    27901 cagcgtgtag cgattgctcg tgcgattatc aatcagcctc gtcttgtcct attagatgag
    27961 ccactttctg cccttgattt gaaattgaga acagaaatgc agtatgagct gcgtgagctg
    28021 cagcagcgac tgggcattac ctttgttttt gttacccatg atcaggaaga agcactagcg
    28081 atgagtgatt ggatttttgt catgaatgat ggtgaaattg tgcaatcagg cacacctgta
    28141 gatatttacg atgagccgat taatcatttt gtagctagct ttattggtga atcaaacatc
    28201 atcaatggta cgatgattaa agactatctg gtttccttta acgggaaaga atttgagtca
    28261 gttgatggtg gtatgcgacc caatgagcca gttgaggtgg ttattcgacc ggaggattta
    28321 caaatcaccc tgccagagga aggaaagctt caggtaaagg tagatacaca gctctttcgt
    28381 ggtgttcact atgaaatcat tgcctatgat gatttaggca acgaatggat gattcactca
    28441 acccgcaagg ccattgaagg agaagtgatt ggtttagatt tcacaccaga ggatattcat
    28501 attatgcgcc tcaatgaaac agaagaagaa tttgatgctc gtatcgaaga atacgttgaa
    28561 atcgatgagc atgcggatgg cttaatcaat gctattgagg aggagcgcaa tgaagaaaac
    28621 ctctagcctc tttgcagttc cctatttttt atggattgtc ctctttgtta tggcaccggt
    28681 tgcccttttg ctttatcaat ccttttttga catcgaagga cgattgacac tagccaatta
    28741 cgagactttt tttagctcat ggacttacct gagaatgggc ttaaactcta tcttatatgc
    28801 tggtatcgtt accttggtga cctttttgat ttcatatccc acagctttat tgttaacgcg
    28861 tttaaagcac aagcagctgt ggttaatgct tattatttta ccaacctggg tcaatctgct
    28921 cctcaaggct tatgctttta tggggatttt tgggcagcag ggtggtatca atagcttttt
    28981 aacctttatg ggcttaggac cacagcaaat tctgtttact gatttttcgt ttatttttgt
    29041 ggcctcttat attgagctgc cctttatgat tttgcctatt tttaatgctt tagatgatat
    29101 tgatgataat attatcaatg ccagtaagga cctgggtgcc aatgactacc agaccttttc
    29161 aagggttatt tttcctttgt cgctaaacgg tgttagagca ggggttcagt ctgtttttat
    29221 tcccagcttg agtctcttta tgcttacgcg tctcatcggt ggaaatcgtg tgattacgct
    29281 ggggacagct attgaacagc atttcctaac aacagaaaac tggggcatgg gctcaaccat
    29341 aggtgttgtc ctaattatcg cgatgattgt gattatgtgg ctaacaaagg agaaaagtaa
    29401 atgaaaaaat ttgccaatct ttacttagcg tgtgttttta ttttgctcta tattccaatc
    29461 ttttacttga ttgtttattc ttttaacaag ggtggagaca tgaatggctt ttctggcttg
    29521 acgctagagc attataagac catgtttgat gatagtcgct tgatggcgat tttattgcag
    29581 acctttgtgt tagcctttac aagtgccttg cttgcaacca ttatcgggac ctttggggcg
    29641 atttttattc atcagagtaa aaagaagtac caaaatgcga tactgtctgc aaataatgtg
    29701 ttgatggttt cccctgatgt gatgataggt gcctctttct tgattctctt tacgtccttg
    29761 aaatttcaat taggaatcct ctcggttttg atgagtcata ttgctttttc cattccgatt
    29821 gtggtcttaa tggtgcttcc tcggttgaag gaaatgaatc aagatatgat taatgcagct
    29881 tatgatctag gagcaaatca ctttcaaatg ctaaaggagg ttatgcttcc ttatctgaca
    29941 ccgggcatta tcgcaggcta ctttatggcc tttacttatt ccttagatga ttttgcggtg
    30001 accttttttc taacaggaaa tggctttaca accctgtctg ttgagatcta ttcgcgtgct
    30061 cgaaggggta tttcattaga tatcaatgcc ttatcaacga ttgtcttttt gttctcaatt
    30121 ctattagtca ttggctatta ttacatttca caggacaagg aggaaaagca tgcgtaagct
    30181 atactctttt ttagcgggaa ttatcggggt tatcttgctg cttgcgaccc tgtcctttat
    30241 tttgcagaaa aaaacgagct ctgctagtca atctgataag ctggtgattt ataactgggg
    30301 tgattacatt gatcccgctt tgctgaaaaa attcactaag gaaaccggta tcgaggttca
    30361 gtatgagacc tttgattcca atgaagccat gtacaccaag atcaaacagg gtggaacgac
    30421 ctatgacatt gctgttccga gtgattacac gattgacaag atgattaagg aaaagcttct
    30481 tgttaagcta gataagtcca agcttgttgg tctagataac attggtcagg agtttttagg
    30541 aaaaagcttt gatccgcaca atgattattc cattccttat ttttggggaa cggtaggcat
    30601 tgtctataat gaccagctgg tggataaggc tcctatgcat tgggaggatt tatggcggcc
    30661 agaataccaa aatagtatca tgctagttga tggtgctcgt gagattttag gtgttggatt
    30721 gaccacattt ggctatagcg ttaactcaaa gcacctaaag cagcttgaag cagctgaaaa
    30781 aaaactacag gccttaaccc ctaatgtaaa agcaatcgtc gctgacgaga tgaaggggta
    30841 tatgattcag ggtgacgctg ctattggtgt taccttctca ggagaggcta gcgaaatgct
    30901 ggacaataac gaccatctac actatgttgt accatcagag ggctcaaacc tttggtttga
    30961 taatctggtg cttcccaaaa caatgaagca tgaaaatgaa gcctatgcct ttatcaactt
    31021 tatcatgaag ccggaaaatg cagcacaaaa tgctgaatat atcggctatg ccactcccaa
    31081 tacaaaagcg aaggctttat tgccagatga tattaaaaat gacccagcct tttacccaac
    31141 tgacgagacc gtaaagaaat tagaggttta tgataattta ggctctaaat ggcttggtat
    31201 ttacaacgac ctttacctac aatttaagat gtatcgaaaa taggtcatgc aagattgaag
    31261 gagctattca ttggaaagct tcttcagtct tttttagctt ggtctggtct caataatctc
    31321 atgagattaa aaagaactag aatcttgctt tcgtctttga tacaatagta gtggtttatt
    31381 aaaatgaaag agatgacaaa atggaaaatc ataaaaacga gtttaccttt tccaaacatt
    31441 caatcatagc ctacgtttgg cgtggcattt tagtcgggat aattgctgga gctattgtca
    31501 gtttgtttcg cttattgatt gagatggtta gtgaggctgt tgttggctat tatcaccaag
    31561 ctcacagcaa tcgcatgctc cttgttccga tagcaggctt tagcttatta gctgtttttt
    31621 tagttggtct tttggtcaag tctgacgcca acattaaagg ctctggtatt ccacacgtcg
    31681 aaggggagct aaagggcttg atgtcaccca attggtggag tgtgctttgg aaaaaatacc
    31741 ttggtggaac aattgccatt tctatgggct taatgcttgg aagagaaggc ccttctatac
    31801 aattaggggc tatgtcagct aaaggcttag ctaagtacct gaaatctagt cgtctagaaa
    31861 aacgtgtctt gatcgctagt ggagcagctg ctggcttatc agctgctttt aatgcgccta
    31921 ttgcaggact gctttttgtt gttgaggaga tttaccacca tttttcaaga ttagtgtgga
    31981 tcactgcctt ggttgcaagc cttgttgcga actttatttc gttgaatatt tttggcctta
    32041 gacctgtttt ggccatgcct aaggccatgc cctttcttgc cttacatcaa tattggctgc
    32101 tcttaatctt aggccttgtg cttggctgtc tgggctttct ttatgaagag gtcattttac
    32161 attttcatag ggtttatgat tttcttggaa agagcttgcg cctagcgccg cattttcatg
    32221 ggctgattgt tgttgctatt atcctgctga ttggctatta tttgccacag ctattgggcg
    32281 gaggtcatgg tttgattatg tccttgtcag agcaaaagct accactgttg actgttcttg
    32341 cttacttctt tattcgattt ttagggagta tgtttagcta tggcagtggc ctgcctggag
    32401 gaattttttt gcctattcta accttaggtg ccttgtccgg aactattttt ggattgattc
    32461 ttcagcaaat aggactgtta gatcgccaga tgattcctct ctttttagta ttgggaatgg
    32521 caggctactt tgctgctgta tcaaaggcac ccttgacagg aatgatctta gtgactgaaa
    32581 tggtagggga tctgaagccc ttaatggcca ttgctgttgt gaccttcgtg gcctacttgg
    32641 tgatggattt gttaaatggt cagcctatct atgaagcaat gctagagaaa atggctatca
    32701 aacacccaac agatctagtg gagccgaccc tgatcgaatt acctgtaagt gagaaaattg
    32761 caggcagata tgtccgagac ctgaagctac ctaaaaacgt tttaattaca acgcagctcc
    32821 accataagaa atcacaggtc gtctcaggtg atacgctatt gatttcaggt gctacgatct
    32881 ttttggtggt caatgaagct gatacaggct ttgttcgaga ggtcttgatg tagagcaagg
    32941 tcggttaagc agtcagcagt agctgtgcta ccgatcaaag aagcagatca gtgctttttc
    33001 tcatctgatg aaaggtattg atttgctttt tttgtgttat taaacctttg ttagcaagag
    33061 ccatagcctt agcagtcgta tctgatgaat acctgctgtc tttttgttat acttaagtat
    33121 caatcaaagg agctttatat gctagaagtt atttcaaaag agctgcgcca ttaccaaaag
    33181 aataagcttg ccgcctatca aaaaaagaac caaggcatag aagctggtgg aattgttttt
    33241 gctggcgatt cgttaatcga atttttcccg ttgaaaaaat atttcaaaca ggtctcaacc
    33301 atttataatc gcggaattgc agggatagac agtcagtggt tgctagagca tattgacagt
    33361 catgtgaatg atctggagcc cagtcatgtg tttatcctga ttggctgtaa tgatattggg
    33421 cttggctttg atcaatcgca tatcgtatcg accattgttg atcttattag tcgtattcgc
    33481 agtcagtcta tttatactag gattagcctt ctgtccttat tgccggtttc tgaaaatccc
    33541 gcctatcagg cgactgtcaa gctaaggaca aatagggcta ttgatgagat taatcaagca
    33601 ttagcaatga taccagcgat tgaatttatt gatcttaacg cctgcttaaa ggacgagact
    33661 ggtggcttag cagctgctta tacggtagat ggcattcatc ttaatgccct tggctatgaa
    33721 cacttagctc aagctattag tccctatcta tgaaaggtaa aggctggagc tgctaatttg
    33781 taagggatct ttaaaaaaca agcactgatg aatcatcatt gaaacccttc agagtgccga
    33841 taggctgcac aatcaaagaa gcattaggtt tgtctatgac gcccttgtgt taagctggct
    33901 tttaggttta tactgcgaga aaatcagtca ttgggctggg agtctcaaag cttagctgtg
    33961 gtaattaaat gcgagctcct gctagcttgt gctgatcaag cagtatagca aggagggact
    34021 gaacttttag tctcagataa tattagactt tttatcctat attaaacgat ttagtgtata
    34081 ataaacagga aggagttaaa atgaaatttg aaaaaaaaca agtcttttat gttgtgcttg
    34141 cctttgtgct ttgttatgct attcaagcta attgggataa tggggctaat attgtcacaa
    34201 ccgtttataa gacaagcctg ccctttcttt atggagcagc agtcgcctat attgttaata
    34261 ttgtcatgag tgcctatgaa agagcttata cttataccct aaaacccttt ccttttgcca
    34321 tgaaggctag aagagggctc tgtatgcttt tggcatattt tacctttatc agcttgatcg
    34381 tatggattat ttctattgta atccctgatt tgattgcaag cattagctcg ttaacgcaat
    34441 ttgatacaag agctatcaag gaggtcatca gtgatttagg tcacaataag ctgattgcac
    34501 gtgccattaa ttacattggt ggagatgcta agctgacaga aacaattacc aattatagcc
    34561 agcagctgct caagcaattt ataggtgttc taaccggtat tttgacatcg gttacagcag
    34621 ttgcctcagc cattatcaat gtggttatca gctttgtctt ttccctgtat gtgcttgcta
    34681 gcaaggaaga gctttgtcag caggcaacta ccttaattga cacctatact ggtaaatacg
    34741 caaaggccat tcattattta gtgggtttgc tgcatagtcg ttttcgtggc ttctttgtga
    34801 gtcagacgct tgaagcaatg attttaggct ccttgactgc cattggcatg tttatcctgc
    34861 aattaccctt tgcaggaact attggagtct tggttgcttt tactgccttg atccctgttg
    34921 ttggtgcttc aatcggtgct gcgataggct ttgttttgat tatgactcag tcaatgtcgc
    34981 aggcagtcgt ctttattgtc tttcttgtta tactacagca aatcgagggg aattttattt
    35041 atcccagagt ggttggtggg tctatcgggt taccagctat gtgggtctta atggcaatca
    35101 ccattggtgc tgctctcaaa ggcattgttg gtatgatcgt tgcagtgcca ttagcggcaa
    35161 cgctttatca agtggtaaag gatcacattc ataaaaagca ggccttacaa aatcgtcagt
    35221 ccagctaatt aacagcatca gatcaaggaa aacgtctatt acaagaccga tttcttggtc
    35281 ttttatgctg tctgattgac tgcgtatggc cttattttta tgctgtggta atgaaaaaag
    35341 ccgtcttatt tatcgaatat cattagtgga ggtaataaga tgtattccat caaaactgat
    35401 cataaattaa tgcctagaga gcgtttgatt cgactgggtc cagaaaagct aagcaatcaa
    35461 gagcaactag cgatcctact taggacaggt aacaaggaaa agcatgtctt agagttgtct
    35521 gcttatttat tgtcaagctt agatagtcta gctgacttga agaaattttc tttacaagaa
    35581 ctacagcgct tatccgggat aggaaaggtc aaggctattg agattaaggc catgctggag
    35641 ctggcagacc gtattcagat agcgggacaa gcagtagcag atcctgtctt atctagtgct
    35701 caggtggctg aaaagatgat gattgaatta ggagacaagc agcaggagca tttagtcgct
    35761 atttatctcg atagtcaaaa taaaatcatt gaagaaaaga cgatatttat aggaaccgtc
    35821 agaaaatcaa ttgcagagcc tagagaaatt ctttattatg cgtgtaaaaa tatggcgact
    35881 agccttattg ttgttcacaa tcatccctca ggcctgacca agccaagcgc aaatgactat
    35941 cacttcacag aaaaaataaa acgatcatgt gattatttag gacttatctg cctagatcac
    36001 attatcgtta gtaagtatga ctactatagc tttcgggaaa aatcagattt attttgagtt
    36061 agaaactatg gataaaccaa tcaaagagcc ttaggtcttc ttctctaata gcctgaagca
    36121 gctctgggtg ccactggaca ccgagaaagg gaatatcagg attgcaggag ataacagcct
    36181 cgatggtgcc atcgttagga tcccttgcaa tcactcttaa gtcctctgcg acctgcttta
    36241 ggctctggtg gtgaaatgaa ttaatcagcg ctcttggacc atagataggg tacaaaggtg
    36301 aagtcttttc gatcactatc tcctgtgata aacagtcaga ggcagtcttt tgccaatggc
    36361 cctcaatgtg ctggtttaga ctgccaccta gagcaacatt tattaactgc ataccgcgac
    36421 aaatccctaa aattggtttt ttctgcgcta gggcttcttt aatgatggct agctcaaaga
    36481 tgtcacgctg gggtgaaaaa tcaccatcaa gtgcagctct tttttcatga taatatttag
    36541 gatcaacatg ctgaccacca ataagaatga ttttatcaac cattgcgaca taggatttgg
    36601 cagccgcctc atccccaatc ggaagaagta agggtaggcc accagatctt gtcacagcct
    36661 cgatgaagct tgttggagca taggagcaag gcaggttatc tagagccttg gtcccccttt
    36721 ggttagcagt tatcccaata attgttttag acacgacctt ctccattaat caagatgatt
    36781 ttggttcata aagtatagca aggtttgcaa ctcgctggtc aaatcaacag attggacgat
    36841 cacacctttt ggaacctgta agtgaagtgg agcaaagctt aaaataccgc gaatgccagc
    36901 ttcaatcagt tgatctgcaa cctcttgagc atagatgctt gggactgtta gaatagccgt
    36961 ttcaatgcct gaattatcca ggtgctcctt aatggtagaa atgccataaa taggaatatc
    37021 atcaggcgtt ttggtgccga ccataggatt atcatcagtg tcaaatccca taacaatctg
    37081 cattttgttt cgatcgtgga agcggtagtg aagaagtgca cgaccaatat tgccgcagcc
    37141 aactaaaatc acatgcgttg ttgagtgatc atttagcaaa tctgcaaaaa aattcattaa
    37201 ttttgtgaca tcatagccaa atccacgtcg gcctaattca ccaaagtaag aaaaatcacg
    37261 tcgaacagtt gcagaatcaa ttcccatagc atcagcaatc tgttttgagc ttgccttttc
    37321 aacctgatca gcataaaagc gtttaaaaat acgataatag agtgataagc gttttgcagt
    37381 cgcttttgga atagatttat caataaccac ttttgtagct ccttctattg ttattttaat
    37441 gttatctatc accattgtag cagatagatt gtgaaatatg caactatttg accattcttt
    37501 ttgtgttttt cgttataaaa tgacttgaca gcacaagcat tggtattttt caaacccagt
    37561 cacctcgagt ataaaaaagc agacaatgaa gcacttgccc tttaggtcag ctgcgatggc
    37621 tgggcttgtc ttgttaaagg caaatgtact gtcattgtct gatatttctc tgagattaga
    37681 agagctcttg tgtgcttagc attctttttt aatgaaaata tcacgctcaa caaggctatc
    37741 cattaaaaag taaaacttgt cctgtagtat gctatgctct tcagatttaa aaatgttcac
    37801 cagtcttaga ccggattggt ctgttatagc tagcttaaag ccatctaaat ctttattaat
    37861 cgtaattttt aaagggaagc cctcacccga attagggact ttttccagta gtcgtgttaa
    37921 ctgatagtga ccaatcttgg tctgactaaa ggttgtgtct cttagggtgt attttttaat
    37981 ctttgggcta atcctgtagc tgtatttgca gtctttaagg gcaatttctt tttcaaatgc
    38041 catatgatcc tcctaaaata tttttgagct gggttgctag tgcgataacg tctttttgag
    38101 tattttgctc tgaaaagcta actcgaatag cttctgtgag acgatgggac tgcttgccga
    38161 aataagctgc caaaacgtga cttggctcaa cagcaccagc tgtacaagca gagcctgacg
    38221 acacagcaaa gcctgctaaa tcaagctgag tcagtaatac atgattttgg taaccaggaa
    38281 agccgatatt aatgatatag ggaagatgac actcattatg attgagctga taagaaatac
    38341 cttctaattc actaagcaag agctgtgata gctctttagc atgctggtaa tgctgtggca
    38401 gccttgagac agcctcatct aatgcttggg tcatgccgac gatattaatc aggctttcag
    38461 tgccggctct ttgtttgttt tcttgattgc cgccatgtaa gaggggggcc aactttaagc
    38521 ctttattgta taaaaaacca gtcccctttg gtccatgaaa cttatgggca gaggcagaga
    38581 gcaaatcaat ccccaaatct gccggctgta ttgggacctt gccaatagct tggacagcat
    38641 caacatgaaa gacagcctga tgctgcttta gcatgctacc aacagcctga ataggcagca
    38701 aatctcccgt ttcgttgtta gcaaacatca tgctgactaa gattgtatcc tctcttaagg
    38761 cagcttggag ctgatttaga tcaatgattc catttttagc ctcaaggtag gtcacctcaa
    38821 agccaaatcg ttcttccaga taggccattg tgcttaacac ggaatgatgc tcaatagcag
    38881 ttgtaatcaa gtgtttgcct ttttcctgat gagctaaggc atagcccttg atagcagtat
    38941 tgttactttc agtacctcct gaggtaaaga taatgtggtt ttctgcagct cctaggcagt
    39001 tggcaatagc ttttcggcac tctcttaatt gtttgtttgc ctgccgccca taagcatgaa
    39061 tactagatgg gttaccaaaa tcatcagcca tagcttcagt catcgccttg atagcagcct
    39121 gactaagcga tgttgtagca gcattatcaa aataaatcat gattagttag tgctttcagg
    39181 tttgtaagaa aacagtggac ttagtggttt tctttcgtga atgcgaatga tagcctctgc
    39241 aattaaatca ctggcactaa gataggttac tgttttaggg atacgatttt tagtcttgac
    39301 agagtccgtg acaatgatct ctttgattgg agcagtctct aaaatatcag ctgcacctcc
    39361 tgcaaaaatc ccatgactag ccactgcata aatgtcagtt gcgcctgcac attctaggat
    39421 cttagctgcc tctgcaaagg tttttcctgt gttgagaatg tcatcaatca agatagcctt
    39481 cttgccagca acatcaccaa tcacatagcc ttcttcgcgc tcagcatcgt cttgtgcata
    39541 atcgataatg gcaattggag agttaagata ctctgctaag cttctagcac gcttgatacc
    39601 agaattttta gggctgacaa taaccgtatc aggtcctgag aggcccagtg gataatagtg
    39661 ctttgcaaaa agaggcactg taaataaatt atcaactgga atgtcaaaaa agccttggac
    39721 ctgaaccgca tgcaaatcaa gggttacaac gcgatcaatc cctgctttgg tcagcatgtt
    39781 tgcgaccagc tttgctgtaa taggctcgcg agactttgca acacgatcct gacgcgaata
    39841 accaaaatat ggcaaaacaa tattgactgt attagcactt gcacgcttac aagcatcaat
    39901 catgatgagc agctcccata ggttatcgtt gacaggaaag cttgttgatt gaatgatata
    39961 aatatcatca ccacgaactg tttcttcaat gttaatcatg atctcaccat cagaaaattg
    40021 acgagatgag acctttccaa gcggaatacc agcagcctta gaaatttttt cagcgattgc
    40081 gagatttgaa gtgagtgaga acagcttgat ttgcttgtca gcatatcgtt cagtcatgat
    40141 aaaattagct ccttacatta cattaacgat agaataacag gttaacagtt attcaagatt
    40201 acaaatagac agtactattt taacaaaaaa acagaaaaat ttcagtcttt ctgttgattt
    40261 tctgtcctct cctaggattt tttaagggtc ttgctaaagc gagcgacctt gcttttggaa
    40321 tatttaaagg tgatctgatg ctgggctaaa aagtggtcaa aatcaacctt tcctcttaca
    40381 ggatcagtca cctctagctc aagctcatag tctttgatac cagcatattg attataatcc
    40441 agcgctagct tgccaatagg agtatctgcc tctcgacgaa tggtagtcag gtttccgaag
    40501 gtttttatag cagataggtc aacgtcaaga gtgctgataa tatcaaggat agctgatttt
    40561 ggtagctgtc ctgtctgaat gatagctttt gcttgggtgt catcaagctc taaattgtac
    40621 tcgcgattac caaccttttc agggactttt aaggttaatt cagcaggagc agcaacaaag
    40681 gtgcgaatgc gaagtgacat tttatgagcc ttgagatcaa aatgatcagt atcaatgtaa
    40741 taatttgtct gggtaactgg tgggacatga gtcatttgag agaggaggcg attatattcg
    40801 tcctttgtca gtaaggtctt gtattcgatt tctaggttag tcatgcgaac gttcctttta
    40861 actatatttt atgctataat aaattgttat cttaatttta tattaatatc cgaggtttga
    40921 caagaaagga gagaaaggat ggctttagat tgggaagaat ttttggatcc ttatatacaa
    40981 acggttggcg aattgaaaat taagctgcgc ggtatccgaa agcagtttcg caagcaaaac
    41041 cgttattctc ctattgagtt tgtgactgga cgtgtcaagt cggttgagag catcaaggaa
    41101 aaaatggcct tgcgtggtgt cttggaagaa aatatcgctc aagatattca agacatcgct
    41161 gggcttagga ttatggtgca gtttgtggac gatattgagg acgttttgtc cttgcttaga
    41221 caaagacagg acatgacaat tgtttatgag cgagactaca ttagaaacat gaaatctagt
    41281 ggttatcgct cgtatcatgt tgtcgttgag tatcctgttg ataccattga gggtcaaaaa
    41341 aaagtattag cagaaattca aatccgtact ttagcaatga atttttgggc aaccattgag
    41401 cattccttga actacaagta cggtggtgat tttccagaag aaataaaaaa acgattagag
    41461 gttacagcaa aaattgcttt ggagcttgat gaagaaatgc gaaaaattcg tgaagacatt
    41521 cgtgaagcac aattgttatt tgatcctgta acacgtcatt tgagtgatgg tgtaggaaat
    41581 agtgatgaca cagatgaatt atacagataa agtaaagcgc gttgctatca ttgcaaacgg
    41641 caaatatcag agtaagcgcc ttgcctcaaa gctttttggc gtctttaagg acgatccgag
    41701 tttttaccta tccaaaaaaa atccggatat tgtgatttca attggcggag atggcatgct
    41761 tctatcagcc tttcatatgt acgaaaaaga attagacagg gtgcgatttg taggcattca
    41821 cactggacac cttggttttt acactgatta tcgtgatttt gaggttgatc aattgatagc
    41881 caatcttaga agagacaccg gtgagcaaat ttcttaccct attttaaagg tagttattac
    41941 gcttgatgac ggtcgcctgt ttaaggctag ggctctcaat gaagcaacta ttaagcgtat
    42001 cgagaaaacg atggttgcag atattatcat taacaatgtc aagtttgaaa gctttcgtgg
    42061 tgatggcatc tctgtatcca caccaactgg aagcacagcc tataacaaat ccttaggtgg
    42121 agctgtattg cacccaacga ttgaggccct tcagctaaca gaaatctcga gcctgaacaa
    42181 tcgtgtattt agaaccttgg ggtcctcagt gattattcct aaaaaagata aaattgagct
    42241 tgttccaaaa agactaggcg tttatactgt ctctgttgac aataaaacct accacttaaa
    42301 aaatgtggtt aaggtggaat attttatcgg caatgaaaag attcattttg tgtcctcacc
    42361 tagccacacc agcttttggg aaagggttaa ggacgctttt attggggata gtgaatcatg
    42421 aggtttgaat ttgttgcaac taaaaaaaca aaggtaaaga cccttttaaa agagcacgat
    42481 gtgtcaaagg gattgctcgc taagattaaa tacaagggtg gcaatatatg ggtaaatggc
    42541 gttgcgcaaa atgccattta tttattggat attggtgatg tggtggctat tgatattcca
    42601 aatgaggagt cctttgagca attgacagcg atttcgcatg accttgatat tgtgtatgag
    42661 gacgaacatt ttctcattct caacaagcct gctggctacg ctagcattcc aagtgctatc
    42721 cattctaata ctatagctaa ttttatcaag gcttattata tcaagcagga ctatcccaat
    42781 aaacaggttc atattgtgac gcgcttagat cgggatacca gtggcttaat gctctttgcc
    42841 aagcatggct atgcccatgc cagattagat aagcagctac agcaaagagc tatcaataaa
    42901 cgctattatg ctcttgtttg tggtcaggag aggcttccag atcaaggtga gattatagct
    42961 cctattggcc gtacggacga cagcattatc acaagaactg tcacgccaaa gggaaagtat
    43021 gctaagacaa gctacaaggt cattgcccgc tatcctgaaa atgtctctct agtggatatt
    43081 acgctgcaca ctggtcggac ccatcaaatt agggtacatt ttgctcatct tggttttcca
    43141 cttttgggag atgatctgta tggtggtcga ttggaccttg gcatgactag acaggcgctg
    43201 cattgtcacc atcttagctt tacgcaccca tttacagaaa gtagaagcga tcatacaata
    43261 tgcttgacag atgactttga gagcgttatc atagatttac agaaaaaaga tagaggttag
    43321 ttaatgagta ttcgtaattt atttggtggt ttaagggaaa aaattgtcgg caaaaacatg
    43381 aagattgttt tccctgaggg aaatgatgag cgtgttgtac gtgcagcagc acgtctaaag
    43441 tttgaaggtc ttgttgagcc aattattctt ggtcaggcag atgatattcg cagcctgcta
    43501 acacagctag gctttgctga gcagcactat acaatcatta acccaaatga ttatgctgat
    43561 tttgagaaaa tgaaagcagc ctttgtagag cttcgtaagg tcaaggcaac gcttgaagat
    43621 gctgatagac tgcttagaga tgtcaattac tttggtgtta tgctggttaa gctaggctta
    43681 gcagatggca tggtttcagg ggctattcat tcaacagctg atacggtgcg tccggcgctt
    43741 cagattatca agacaaagcc aggcatttct agaacatcag gtgtcttttt gatgaatcgc
    43801 gaaaatacag agcagcgttt agtgtttgct gattgtgcca ttaatattga cccaactgct
    43861 caggagctcg cagaaattgc ggtaaacaca gcagatactg cgaaaatttt tgatattgat
    43921 cctaaggttg ccatgcttag cttttcaaca atgggctctg ctaaagcccc acaggttgaa
    43981 aaggttcaag aggccgtccg tattgctaag gaattgaggc cagagcttgc tttagacggt
    44041 gagcttcaat ttgacgcagc ctttgtacca agtacagcag cgatcaaagc ccctgattca
    44101 tcagtggcag gccatgcgaa tgtttttgtc ttcccagatt tacagtctgg aaatattggc
    44161 tataagattg ctcagcgctt aggcatgttt gatgctatcg gaccaatcct gcaaggattg
    44221 aacaagcctg ttaatgattt atcacgtggc tctagtgcag aggatattta caagctagct
    44281 attattacag cagcgcaagc gcttgaaaat gagtctatca attaactgct aatagccatt
    44341 aagttcacaa ggcttagcta tagtagatgt tgcttaaaac gagttggata agccagctcg
    44401 ttttttcaga aagtgaggaa ggaaatgaca aagattgcat tagtaacagg cgcctctgct
    44461 ggctttggta aagccattgc agagcagtta atagcccaaa acatcaaggt gatcggagca
    44521 gcccgccgca tagaaaagct aagagagcta gaaggtattt ttggttctga gaggttttat
    44581 ccgcttcaaa tggacgtttc agaaccaact gccattgata aagcacttgc agaattacct
    44641 aaagaatggc aggccattga tattttagtt aataatgcag gactagcctt aggacttgat
    44701 aaggcctatg aggctgatgt cgccaactgg ctaaccatga ttaatactaa tattattggg
    44761 cttatctatt taacacgtca ggtattaccg caaatggtaa gcagcaacaa tggcatgatc
    44821 atcaatatcg gctcaactgc tggcactatt ccctatccgg gagctaatgt ttatggggct
    44881 tcaaaagcct ttgttaagca gttttcgctt aatttaaggg cagatttagc aggaacaaat
    44941 atcagggtga ccaatattga gcctggcctt tgtgagggaa cagagttttc tcatgttcgc
    45001 tttaagggtg accatgagcg tgttaaagca ctttatgcag gtgcacatgc tattcagcca
    45061 agggatatcg caaatactgt ctcatggatt attgatcagc cagagcatgt taacattaac
    45121 cgcgtggaaa tgatgcctgt ctcacaaagc tatggttctc agcctgttag ccgtcatgac
    45181 taagaattac aagagcagat gtaaaaggat tgtcgaagtg caacccaaaa agacttaaag
    45241 cctagctgtt ttatagcctg gctttaagtc tttttctcta atttttctta gaaatgatcc
    45301 gaaagagaag gtccagatgt gacatctgac cacccaacaa tggcctgccc tgtttcttcc
    45361 aaatagtgct gcagcatagg cttgaagtcc aaaatcatgt catagacccc aacaaattgc
    45421 ttggtatcat cgtacaaggc ttgatattgc tgcatataaa tatgatcctg tgaagcagtc
    45481 ggaataagat acagcttact gccagttgcc gccttgtgca aatcagtcaa gatccaatcc
    45541 tcaatgacat catgcttatc agaagcaaaa aaattgccat taaagcgatg attatcaaag
    45601 atgatctgcc cctgatgatc agcaattcta gcctgaaggg gaagataggt taaaaaatgt
    45661 ggggctaagg cttggtaaaa ttgcatgagg tatttagcaa gtcttaaagt ttgctgacta
    45721 tcagtaaagg tatgatcact aacggtaaat ccttgctctt tgtctgcctg attaaaataa
    45781 agtacaggta gtgaggcttc aaggttctga aaggtaaaaa tggcctgagc ctttttgagc
    45841 tgctcagtag tcagctgacg gacaatagtg atatgaaaca gatagctaaa ctcttgtgat
    45901 aaggtggtaa aaaaagtctt ttgcagatta ttcttatcat caaccagtgc taaggtataa
    45961 atcgttttag tcataaggct atcatagctt tattttgttt aaatagcaat gaaacagcct
    46021 tttagtctac agacttagtt gatagcttaa taaaagaaag caatatgaaa aaat
//
LOCUS       DARYXS010000007        37864 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.007, whole genome shotgun sequence.
ACCESSION   DARYXS010000007 DARYXS010000000
VERSION     DARYXS010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37864
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.007"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(80..1285)
                     /locus_tag="TV193_000292"
     CDS             complement(80..1285)
                     /locus_tag="TV193_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEL1512532.1"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLADVIDKV
                     YTRDVFGRD"
     gene            complement(1538..2791)
                     /locus_tag="TV193_000293"
     CDS             complement(1538..2791)
                     /locus_tag="TV193_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1512533.1"
                     /translation="MRTLKNLITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRDTGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVFAATGHLNVRNRQTNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSVYRREVVVPNIDRYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            complement(3188..3808)
                     /locus_tag="TV193_000294"
     CDS             complement(3188..3808)
                     /locus_tag="TV193_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512534.1"
                     /translation="MRKYLQIRLYELSHYVEIIISIILVISLLVLTGRLALSLTGIFT
                     IKSGIDTYLQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKD
                     SLLSVIALAILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRD
                     LMLRHLEEEGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(3849..3944)
                     /gene="ffs"
                     /locus_tag="TV193_000295"
     ncRNA           complement(3849..3944)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="TV193_000295"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            4121..5347
                     /locus_tag="TV193_000296"
     CDS             4121..5347
                     /locus_tag="TV193_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1512535.1"
                     /translation="MKNKLSLFLLAALTIVGLSACAWRSNPLADKEQQFGLTGARRQQ
                     VLDQIDQRYYYQQLSQAEKENYLLLYDSLSAFHEVTSLAPASKHSLMTTIDAFMMDNP
                     AFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDDIIADMPATNDYERVRY
                     FYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYAQAFQFLCQKA
                     GIPVAYIRGSVTFDRSQDVFTHAWNTVQIAGKNYAVDTTFGDPVFDQNESIKQLEVNY
                     NFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLNHSYFTAFDRP
                     DILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQHSDSYHSLFQAYWPNAAGYFYS
                     LHPSTFSISISIINQQ"
     gene            complement(5457..5951)
                     /locus_tag="TV193_000297"
     CDS             complement(5457..5951)
                     /locus_tag="TV193_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEL1512536.1"
                     /translation="MSYSKQEQEYFMREALKEAEKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLEVGLLADDCAKLMQTFFRQRRDQKKQDK
                     ESKI"
     gene            complement(5948..6730)
                     /locus_tag="TV193_000298"
     CDS             complement(5948..6730)
                     /locus_tag="TV193_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1512537.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGSRSLNEL
                     EKEINPLDLDAVIISHYHPDHVADLGVLRHYYQLYPRHLGKPRLLPIYGHDEDEAEFA
                     KLTLPGVSKGIAYQVDRVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLVFTGDTG
                     YFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLTHMPPLP
                     PEGIDPKRHLEVLRQQAQGYAGQIPVDLALPHRAWDLGSLSQ"
     gene            complement(6829..7368)
                     /locus_tag="TV193_000299"
     CDS             complement(6829..7368)
                     /locus_tag="TV193_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEL1512538.1"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPVPIVLQNLGVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            complement(7372..7683)
                     /locus_tag="TV193_000300"
     CDS             complement(7372..7683)
                     /locus_tag="TV193_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512539.1"
                     /translation="MRNCFGIALDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTDHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPAYHKHQDIYFSKE
                     L"
     gene            complement(8070..8207)
                     /locus_tag="TV193_000301"
     CDS             complement(8070..8207)
                     /locus_tag="TV193_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1512540.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     gene            complement(8591..9835)
                     /locus_tag="TV193_000302"
     CDS             complement(8591..9835)
                     /locus_tag="TV193_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1512541.1"
                     /translation="MRNKKTSIRLVQKYGICSAVVALATIASLGIGNDVRAEDFTYPS
                     MYNQGYFFQQFIKKEILNPGSGSSSDWETSTHYNNGRMLENVLRYLWRVEQFLKKSTG
                     QSEQLYKLYEKDSLGIPGPQGPMGPAGPQGLRGERGPVGERGPIGPQGPEGKPGQQGP
                     KGDTGPQGEPGQQGPKGDIGPQGEPGLPGPKGDTGPQGAPGQQGPKGDTGPQGEQGLQ
                     GPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQGEQGLQGPKGDTGPQGAPG
                     QQGPKGDTGPQGAPGQQGPKGDTGPQGVPGQQGESQKVPEVPKAPETPEKKEQPQAPK
                     EPETPKAPEQSPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPF
                     FTLAALSVIASAGVLGLKKKQD"
     gene            complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TV193_000303"
     CDS             complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TV193_000303"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEL1512542.1"
                     /translation="MTNYPITYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQAILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVSMDFPGYSI
                     GGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYTCQHYTRAYLRHLLKADETFGMR
                     LTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLERYGYNSSSRNF"
     gene            11812..12657
                     /locus_tag="TV193_000304"
     CDS             11812..12657
                     /locus_tag="TV193_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEL1512543.1"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGASYFPLIVLIMLTVFTLSAAYTMLDVIRYYRREVSFSEATIAFSGNLF
                     GKVLVLLIIKGLLFILWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     FIIGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLIYIYVLPYYTTADVTFYHHLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            complement(12853..16815)
                     /locus_tag="TV193_000305"
     CDS             complement(12853..16815)
                     /locus_tag="TV193_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEL1512544.1"
                     /translation="MFKPYTDGKQRFAIKTFKTGAASVLVATLFLTLGLTTVSADEQQ
                     VTASAAIATTLEAQEAVDQQAADQSATAAQDTAAEGSSETLPVVIGTATTETTDSKSQ
                     VAAAEQATEASAEETTKQEQTEVSQAVETTNKTEAKDYIYLSDETRVNPSKVGHGSFL
                     QDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLGVDYSRR
                     GKDDGVSFNIYKSKDGKSWESLVTTGTVTGTSEAVYVDLDITGAKYVKLIANSLKNNG
                     NDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNLALVLER
                     EFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKTLNALGD
                     LYATNKADLEDKGNGYVYKKMMLATAVAYCKEIKSFVVNYGGTYLASDPVLKYQAFKE
                     LYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASYTSGYSY
                     TKYKNIGYGGADMRSADNQAQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLMEKGAVCW
                     GLSNLGVAVNEVFGIPAVNIYQNDHEAYLVYRQDDQGNGIWDIRDNVYGNRWAISYSR
                     WGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLIANVYEA
                     GSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAYTYYPQV
                     MVEAIKRITPNISDQAAKAELDLLSYNALIAAKTATDKEVLQSNEVRIIANYILTGNP
                     IETASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLAKLNIED
                     GILVGFDAVSATYRINLTKAAAPTNSSLYGNDLENRLIGAIEHLEVSLDNGQSWQAYD
                     GTERFNDTVTVLARYRAHGTSLASDSVTYTFTADSTDPTMHYISIDDIQAVTYANEQS
                     GRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNGMIHSAK
                     VDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQANKFVS
                     GSAYRFFEDISSPIEAPVRNDILALKDSILTILKETNTATKEIESFAITNSGLTAATT
                     EKNQAIQGKILETIKDLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKAAGPLYV
                     LAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAAKTAVNT
                     ALMEKLQQLLPGDYFIDLAGLPTAASIDELLDSQLFIYYRESHWTTAYALDRGAFQQL
                     "
     gene            complement(16950..18776)
                     /locus_tag="TV193_000306"
     CDS             complement(16950..18776)
                     /locus_tag="TV193_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEL1512545.1"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHLNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASPTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKNSNSNKTELRKSLEEAKLKLSQPEGTYSDESLQALQSAVTIGKTYLNS
                     DPDQNTVDQSVTTIDSAITSLVNLNALNEAINQATPFITDGKEYPKEAYDGLVQKLAA
                     AAKLQNSFGPSQGDVDKAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLALT
                     SESLKELYNKAIEAAGTFYRTVNKDKERKDISLYELERYTTETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLVKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVDPVDPVDPVDPVD
                     PVDPVDPVDPVDPVDPVDPVDPVDPIDPADPVKPSDPEVKPEPKPESKPEAKKEDKKA
                     ADKQQVLPATADTANPFFTAAALAVIACAGQLAIVSRRKESN"
     gene            complement(19136..19609)
                     /gene="perR"
                     /locus_tag="TV193_000307"
     CDS             complement(19136..19609)
                     /gene="perR"
                     /locus_tag="TV193_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEL1512546.1"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQTKQGKDTDY"
     gene            complement(19646..20098)
                     /locus_tag="TV193_000308"
     CDS             complement(19646..20098)
                     /locus_tag="TV193_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEL1512547.1"
                     /translation="MIDTFQNPSDETITSYLESSKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPRLAGQSVLGEVVYASLAAIPFKVDIANVFRRSEYLPQVAQDFLACQG
                     QVFWAQLGLYSQEAEELLRSAGKADIVMNRCIKIDYLRLISKQDQDSC"
     gene            complement(20338..22980)
                     /gene="polA"
                     /locus_tag="TV193_000309"
     CDS             complement(20338..22980)
                     /gene="polA"
                     /locus_tag="TV193_000309"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEL1512548.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLG
                     ALGIAFYELEHYEADDIIGTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKK
                     GVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGS
                     LEGIYEHIDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDR
                     LSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYH
                     REELIGFAWGNQGQIYASADISLLTTKLFKKVLEQPIATYDFKRSKVLLSHLGLDLPA
                     ASYDARLANYLLSTVEDNEMATLARLYTTISLDTDEVVYGKGVKRAVPDKAVLLGHLA
                     RKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQ
                     NKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGA
                     DIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYI
                     DTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKALVKETM
                     ESAVSLAVPLRVDESAGKSWYEAK"
     gene            complement(23404..25134)
                     /locus_tag="TV193_000310"
     CDS             complement(23404..25134)
                     /locus_tag="TV193_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEL1512549.1"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNALMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISVLLGIPLGIWMAKNKIVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLALRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTMMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMLSSSADKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQKA
                     YSNLADWELVAASTGAMTTSLDQAVKKKEPIVVTAWSPHWMFAKYDLKYLADPKKTFG
                     SKENINTIARRGLKADLPAVHRIVDHFHWEKEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            complement(25152..26348)
                     /locus_tag="TV193_000311"
     CDS             complement(25152..26348)
                     /locus_tag="TV193_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEL1512550.1"
                     /translation="MGTILEVRHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGRDISKLSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            complement(26548..26802)
                     /locus_tag="TV193_000312"
     CDS             complement(26548..26802)
                     /locus_tag="TV193_000312"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512551.1"
                     /translation="MLLDMTSSYGQSKLTLCLADLIAIGSLLGSLSIGLVAGQESDRS
                     IKSARGGCWVSSQGAKCQKGLLAVVCSGLLSAWLTSDITA"
     gene            complement(26855..27946)
                     /gene="ulaG"
                     /locus_tag="TV193_000313"
     CDS             complement(26855..27946)
                     /gene="ulaG"
                     /locus_tag="TV193_000313"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEL1512552.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(28141..29787)
                     /locus_tag="TV193_000314"
     CDS             complement(28141..29787)
                     /locus_tag="TV193_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEL1512553.1"
                     /translation="MIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHLDK
                     INEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVADYHYVMKGDERRSLSAIYIA
                     VATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHPMA
                     LIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQASLG
                     KTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKRDFNLIWKRKEYQIAKALASEL
                     YHNFKLHLDDIEVGMIAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHF
                     THKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQAWQ
                     IRLTDDDVAYLTIHLGGELRHSHADWDKTKLVIVSDDGIGIQKLLLKQCQRYLPNCQI
                     EAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPVLIVNPILSDDDIIRLIRFSKQGRL
                     SDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            complement(30091..30807)
                     /locus_tag="TV193_000315"
     CDS             complement(30091..30807)
                     /locus_tag="TV193_000315"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEL1512554.1"
                     /translation="MAKRLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFASRGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPTYIMD
                     KHYLRKHGPNAYYGQKGSRH"
     gene            complement(30807..31670)
                     /locus_tag="TV193_000316"
     CDS             complement(30807..31670)
                     /locus_tag="TV193_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEL1512555.1"
                     /translation="MARPIGIYEKATPKHFTWLERLQFAKVLGFDFVEMSVDESDARL
                     ARLDWSKQERLDIVKAIYETGVRIPSICFSGHRRYPLGSSNPETEATSLELMKKCIVL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQACTWAEEAQVILAIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWEAMFDVLKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLS"
     gene            complement(31675..32340)
                     /locus_tag="TV193_000317"
     CDS             complement(31675..32340)
                     /locus_tag="TV193_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEL1512556.1"
                     /translation="MMTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQV
                     GSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALK
                     AIKEERGERGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNK
                     VKALIDMGFRVSVTGGLDINTLKLFEGVNVFTFIAGRGITEAEDPAAAARAFKDEIRR
                     IWG"
     gene            complement(32435..32920)
                     /locus_tag="TV193_000318"
     CDS             complement(32435..32920)
                     /locus_tag="TV193_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1512557.1"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLTKPVTFSDGKEASVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLVACHTPAEVLALVDESKNSPYLEGLDLD
                     S"
     gene            complement(33136..33414)
                     /locus_tag="TV193_000319"
     CDS             complement(33136..33414)
                     /locus_tag="TV193_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1512558.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            complement(33529..34962)
                     /locus_tag="TV193_000320"
     CDS             complement(33529..34962)
                     /locus_tag="TV193_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1512559.1"
                     /translation="MKMLIAPLNWFSQDILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGAGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGS
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQLQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLASFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGAGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFARAKDKEAYYRGEAQ"
     gene            complement(35445..36065)
                     /locus_tag="TV193_000321"
                     /pseudo
     CDS             complement(35445..36065)
                     /locus_tag="TV193_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(36067..36684)
                     /locus_tag="TV193_000322"
     CDS             complement(36067..36684)
                     /locus_tag="TV193_000322"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512560.1"
                     /translation="MKLSNLLVVGMKACLTGLLIHLLLIKANMTGERDFHNLVCYRLL
                     MPFPVIEGETADFVKVITLLGLSFNSFYFTISFLADLAEGTKEIFRFHARSQLVFFNK
                     LWRTSTIFYIKEWLLFIVLILGVLMTYYGAPYHIERLCYLMVSWLTIDICLIYVMIRY
                     ASSAVVAMILFASLTLIRYFLFDVWWCLLLIVLVHMLYDNYYKES"
     gene            complement(36671..37375)
                     /locus_tag="TV193_000323"
     CDS             complement(36671..37375)
                     /locus_tag="TV193_000323"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512561.1"
                     /translation="MKHILFFDTSAVDLSGGIEVKKSLLLSMIRLDSVVFDFSFYQSF
                     IYPLVMILVAYAYYYLKSRHLKYLIGRKSDYGKRCIFLKLQLSLYVLLSFYIVIFALT
                     LVSWLNGVAHMNGNLMPYFDQNSILRFFGQGATTFIAYYCLVKSLALFVHTYFVCFLV
                     DYLQSFIKSSMLYLILMWALSPLLYSYLPPKYVLMTSLMSTSYSDADIPYLLSPYLGL
                     VGVCIVLKLRKHHEII"
     gene            complement(37530..37784)
                     /locus_tag="TV193_000324"
     CDS             complement(37530..37784)
                     /locus_tag="TV193_000324"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512562.1"
                     /translation="MKSAAPYYVVNLDSRGRNREIVVRHYLANSNGQRRSDIDKTWTG
                     DRGIYTQDTKSGYLYALHLVRENWWDGATTISGSWSPDNW"
BASE COUNT        10913 a         8880 c         7406 g        10665 t
ORIGIN      
        1 tgggataatg gcttttctga cctttgtcat gagttcctcc ttgatttgtg gttccttatg
       61 tgtgccactt gttttctgac tagtctcttc caaagacatc tctcgtgtaa accttgtcaa
      121 tgacatctgc taggtcgtcc tcaaagcgat ttgacacaat gattgtagac tcgtttttga
      181 actgctctaa atcctttaca actctatagc caatgtcctc accaagcatg ggttcgtaaa
      241 tgacaatatt aaccccatag tcgttgatga tatcaataat atctttaatg gcgctttctc
      301 ggaaattatc agagttgctt ttcataatca agcggtaaaa gccaatcgtt aatggtacac
      361 cagcctgctt ttgactagag gctctgtcta atatttgttc agccaaataa gattttcgta
      421 tcttgttgga ttcaacaatc gctgacatca aggactgggg aatgcctcta taatttgcca
      481 acagctgctt gctgtccttt ggcaggcaat agccgccata tccaaaggaa gggttattgt
      541 aatggttacc aatgcgctga tcatgacaga ctccttcaat cacgcgctga gcatctagac
      601 ccttgctttc ggaataggtg tctaattcat taaagtaaga cacccgcata gccaaaaagg
      661 tattcgcaaa tagcttgacc gcctcagcct cctgtgagcc cataaataag accggagtat
      721 ccttgctttt ggctccttcc tttaaaagac cagcaaaggc tttagcagcc tgaataaccc
      781 ttggtgagtc gtccttttca taagaaacaa tgattcgact tgggtaaagg ttatcgtata
      841 aggcttttga ttctcttaaa aattctgggc taaaaataat acgatctgtc tggtattttt
      901 ccctaacatg cttgataaag cctagtggta tggttgattt gataataatg gttgctgacg
      961 catttaggtc taggacctgc tcgatgacct cttcaacatg ccttgtgtca aagtagttgc
     1021 gttcgctgtc ataatttgtc ggagtagcaa tgataataag gtctgcattg ctataagcgc
     1081 ttgcgccatc aagcgtcgct gtgagattta gcggcgcatt ttttaaatac tcctcaatat
     1141 cagcatcctt gattggcgat atgccttgat tgatcaatct caccttttca tcaataatgt
     1201 caacaacagt gacgtcatta tgttgtgcca gtaaaatact caaggatagg ccgacatatc
     1261 ctgagcctgc tacagaaatt ttcacttcat tttttccttt gataccttag tacagttagc
     1321 tactgccgga gctcaggtgc cacacctgaa ggaccatgat gacctagccc tcataccaaa
     1381 gctgacgctc agcctctggt tcgtcttcac agggctacaa gctaaaagct cttaactcaa
     1441 gtacaagtgg actagcttta tttgatgagc tgcttaactc aagatgcttt gttcactcct
     1501 agcttagctc ccttgtcaga acctaggtct agttggttta taataatttt ttacgtgttc
     1561 cccagtcagc atttctaata gtaaaaagag aatacaattt caagggctgt aggacaaaca
     1621 aatgcagcac cccataaaac ggagataaca agaaggacag cgggtgctta agcatgtaat
     1681 gaatgttccg acaaagagca acaatgaaga taatcaccag aaaggctaaa accctgagcc
     1741 aatcaaattc tctgacattg cctacaaaga aatccaccac agaataaaca agcatcataa
     1801 acatagacac ctcaagtatg gtccataggg ctacaaaagg attgttcatg attttcttaa
     1861 cagaaataat ggactctcta aagaaggact tgttccagcg gttttgctgc ttcaagtaag
     1921 tagacatctt gtcaggaaca tctgtaatac atttagcagt ggattgataa acagtctttc
     1981 ctaaatcagt tgcatagttg gtcaagcacc tgtcatcacc gatacttaca ggaataccca
     2041 ggaaggtctg gttgatgtat ctgtctatat taggaacaac cacctcgcgt ctgtaaacgc
     2101 taagtgggcc tgagcaaaca aggatattac ccgtaactga ttgggcagct cgttcaacgc
     2161 caaaagcatt atcatagcga atatctgtca agcgtgttaa gagattggtt tgtctatttc
     2221 tgacattaag gtgacccgtc gcagcaaaaa cagttgggtc attaaaggtc tttaacagct
     2281 cctctaaagc atcagggtag atataagtat ctgagtcaac ggtcaaaaag acatcagcgt
     2341 ctgatctttc aaaggcccag gcctgtgcat gacgctttcc ttgatttttc tctgaccgat
     2401 gaacaatgac attgcttgat aggtcaccag tgtcacgcac atagtcttca atgcgcttaa
     2461 tacctgtctc atcagcactt ccatcgtcaa caacataaat ttctgctagg ggataggttt
     2521 gctgctgaac actttttaag gtctctagca atgactcagc gtcttcgtta taagagggaa
     2581 taatggctgc aaccttatat tgcccagccc ttcccttaaa tggcttgtaa aaaaaagata
     2641 aggacatttt gactaataga taagctatca gcaaaaagcc ataaattgac aagcttcctt
     2701 tagcaccaaa gagataaaca ttgacgtaaa tcaacagtac ccaaaaaata ctaaaggcca
     2761 caacagttat gaggtttttt aatgttctca ttgtgattgg tttgctcctc tcttgcgctt
     2821 tgtattttgc ctttaaacac taaccataat ataccatctg tcacagcaag caaacaaggt
     2881 cattaattta ccattctatt aaagatagat taatcttagt gtcaatacag ctttttctaa
     2941 gatttgccta tgctcaccaa gtcatcaatc ccctacaaaa aacaaatgat agcctgagtc
     3001 tacctgtggc tatcgctagc atgtgcctga taacaagcag ctaaatggcc cgtccaaaac
     3061 taaggcgctt tggacagccg cttttcgctc tcttttttga catcaaaaaa gcagccctta
     3121 tcaggccact tcatattggt aacaaagcaa ttctataagg agctccttaa aggataaggg
     3181 caagagatta ctttagagac ttgatgatct caatgcgagt gataaccccc tcatgcatat
     3241 gatctactct taaggcaaca tcagaaaaag caatagatgc cccaatcgtt gcagtctttc
     3301 cttcctcttc caaatggcgc agcattaaat cacgcattag ctcgtttttg ttaataaccg
     3361 gcagctcgac acgcgctagc acattagcta ttttgacctt ttgactgccc cgaacgataa
     3421 tgcttgaagt atcatcaaag cttgtaaaaa ggtattttcg cgtcgcaaat aaaatagcaa
     3481 gagctatgac actcaacaaa gaatccttag cagagccatg agcgacaaca atttgccggg
     3541 caatcgcaaa caaaagcacc tcaataatgg ttcctgaggt atgcttactc agcattttaa
     3601 tcagctcgac accaatagca atactcatgg cctggtttaa aaagctctgt aaataggtat
     3661 caatgccact ttttatggta aaaatacctg tcaagctcaa ggccaagcgc cctgtcagca
     3721 ctagtaacga aatcaccaag atgatggaaa taataatctc aacataatga gatagctcat
     3781 acaatctaat ctgcaaatat tttctcatag caactcctta tcattattat ataaaaaatg
     3841 ccactatttg aaaataaaaa aagagcacac acccgatatc gcttagggct gctggattcc
     3901 tcccctgacc cacttcacgc acaagtgttg ctccaccttt attgtagcat atattgtacc
     3961 ctaaaacaag tcttatttca aaaacgtctc acatctggct cataaagctt aattagctca
     4021 acagcaaacc aagcaaacgc tatcaataag gccagtcctt aaagctaagc ccgactagac
     4081 ttgtgctata atggtactaa caaacctgag tggagatgat atgaaaaaca agcttagcct
     4141 attcttgctg gcagcactta ctatagtcgg tctctcagcc tgtgcatgga gatccaatcc
     4201 tcttgctgac aaggagcagc agttcggcct gactggagca agacgtcagc aggtgcttga
     4261 tcagatcgat caacgttatt attaccagca gcttagtcag gcagaaaagg aaaattacct
     4321 tctcttgtat gatagcctct cagcctttca cgaggtgact agcctagcac cagcttctaa
     4381 gcatagcttg atgacaacca ttgatgcctt tatgatggat aatcctgcct ttttctggat
     4441 tacctcagcc aactaccgct tggaacgctc ggatcaggtg gccttcgtta cctttccatt
     4501 gccagagaag gtcgaacaaa catatcacag gcttcaagcc attggagatg atatcatcgc
     4561 tgacatgcca gcaaccaatg actatgagcg cgtgaggtat ttttatgagt ggatcatcaa
     4621 gcaaactgac tacaatagag atgcctttga ggcatatcaa tcgggtcatg aggccttgat
     4681 agcctctaat caagacattc gcagtgtctt tcttgatcat ctttctgtct gcaacggcta
     4741 tgcacaggcc tttcagtttc tttgccaaaa ggccggtatt cctgtcgcct atattcgagg
     4801 gtcagtcacc tttgatcgat cacaggacgt ttttactcat gcttggaata ctgttcagat
     4861 tgcaggcaag aactatgctg ttgacacaac ctttggagat cccgtctttg atcaaaacga
     4921 atccattaag caactagagg ttaattataa ctttttatgc ttgccagacc agctcatgaa
     4981 gcagtcgcat caagccagca gggatattgt gatcaatcag acagaaacct tgaccgatgt
     5041 ctggacaatt cctgagtgct cagacgattc tctgctctat actaagctca atcacagcta
     5101 ctttactgcc tttgatagac cagacattct ggccagtctt gagcagcaat taaggactaa
     5161 tcagccacag accagcttac aatttgctaa tcaggacctc tacaaccaaa tggtaagtga
     5221 tcttgagcag cattctgaca gctaccatag cctgtttcaa gcttattggc ctaatgctgc
     5281 tggctatttc tacagtctac accccagcac ctttagcatt agcattagca ttatcaatca
     5341 gcaatagcct aataccctga cagacaagta caagcgctta tggcatggct ctaccagcca
     5401 ttaaagagct gtgctaggct ctcaagggtc ttttttcttg ctaatcgctc aatgggctaa
     5461 atcttacttt ccttatcctg ctttttctgg tcacgccttt gccggaaaaa ggtctgcatg
     5521 agcttggcac agtcatcagc taaaagacct acctcaagct gtacacgatg gttcaggcgc
     5581 tcatcggtta agatctgata aagactacca gcaccgccaa acttttgatt gctggcccca
     5641 tagaccacat gaggaattcg agctagccca atggctccgc tgcacatgac acaaggctca
     5701 atcgtcacaa aaagagtcgt atccaagaga cgccaattgc cttcgtgcgc attggcttca
     5761 ttaatggcca tgatctcagc atgcataatc gcctgattgc gctcctcgcg agcattgtga
     5821 ccacgcccga taatgtgacc agccttcaca ataacgcagc caatcggtat ctcgtccttt
     5881 agcagcgatt tctcagcctc cttgagggct tctcgcataa aatactcttg ctcttgtttg
     5941 gaatagctca ttgagataga ctccccaaat cccaagcccg atgtggcaga gcaagatcaa
     6001 caggaatctg accagcatag ccttgagctt gctgtcgcag cacctccaaa tgcctcttag
     6061 gatcaatccc ctctggcggc agaggtggca tatgggtcaa gaccaagcgt ttcaccttag
     6121 cacggctggc aagctgccca gcctcttttg aggtcaaatg cgccatatga tgttcattgc
     6181 cttcataaag gtacacatct gctaaaaaca catcagcctc cgcagcaaaa tcagccagct
     6241 cttcaaagta gcctgtgtct cctgtaaaga caagcacctg cccagttgct ctttccacaa
     6301 tacgaaaagc atagcacacg accgggtgaa ccgtcttaat aaaggtaatg tcaaaaggtc
     6361 caagagcttc aaccctatca acctgatagg caatgccctt tgagacacct ggcaaggtta
     6421 gtttggcaaa ctcggcctca tcttcgtcat gaccgtaaat aggtagtagc cttggcttgc
     6481 caagatgcct tggatagagc tgataataat gacgcaaaac acccaagtct gccacatgat
     6541 ctggatgata atggctaatg ataacagcgt ctaaatccag cggattgatt tctttttcta
     6601 attcgttaag agaacgacta ccagcatcca tcaataattg aaaaccatca tgccctgtca
     6661 caagataggc tgtcgtccca gcatcttgat agggataggc tccccaagag ccaagcgttg
     6721 ttaatttcat cacaaaacct tccttcatgc tttgttctta ttataacaaa aaatagcagc
     6781 aaaaaataag tcctagtgcg caagagctag gacttacagg cttagtattt agctgttggt
     6841 gtttaaaaag ctgtctttat agctaacagc aagcgccgtt gcgatgactg ccttaatagt
     6901 atctcccggg ataaagacaa ggctagcaac gagcgatcta gtgagcggca tgtctgtata
     6961 aaccgctagc caaatagtcc ccaacagatc caccagcagg acaccagaaa taaagattgc
     7021 taaaaaagca agagaccgat accttgctag ccagctgcgg tacaagaatg caaaaaccaa
     7081 tggaacaaag agccaggcca aaacatagcc agccgatggt cccattagga ctggaacagt
     7141 tgttctagag cctgaaaata ctggcaagaa cagaccaatc actagaaaaa gcaggataga
     7201 cagggttcct tttttcccac ctaaaatcaa gccagcaagc atgaccccta agttttgcaa
     7261 aacaatcggc actggaacaa agcctagagg aatcgctgga ataagaccta aaataatgat
     7321 taaggtggtc atcattgcta ccttcactaa gtccttggtt gacaacatat ctcataactc
     7381 ctttgaaaaa taaatatcct gatgcttatg ataggctggg ttaaaagggc taaaacaaaa
     7441 aggacagctg ccgcactcat attcggacct tctcagcagt tgtcggcaat gaccacaaat
     7501 caccggatag gtctccttgt ggtctgtcgg ctcaaaagca tgatcttgaa gcgtgtcatg
     7561 acaatgataa caggcataat aagcctgaca tcgagcacac ttcaagccga caatatccag
     7621 cactgtgtga taatgtacac agcgatactc ctgatcaagc gcgataccaa aacagttcct
     7681 catgtcttat cctcttatta aaaggataaa gcattcgttt tattttgtca acctatattt
     7741 actaataggg ttactaatca cataagaaga acaccaaaaa agcataaagt agtcccatag
     7801 gcagctgctt tttaccagta ccacacaaat agctatatga ctataaaggt tggcttaaga
     7861 aggttcagat ttaaccgagt gtgggaaaaa gattaccaat ctagctgcca aaatacgggg
     7921 tctcgtttga ctatttttcc ctattgggat ataatgagaa cagaaaaagg gcagttgctc
     7981 taaacaacta ccctatgcag aaccgtttaa gacggtggca tatctttaat tattaaaaaa
     8041 taatcgtcga cctaccaaag ttcagacggt tattttttat tgtttaatat gacgattgca
     8101 acgactaagc tgattaaggt aagtaagaaa ctaccaaaag ccagcatgag ttgaagggcc
     8161 tcgtaagtag acaataaaac gctcctttct gttggatttt gatgcattgc ccataggtat
     8221 caccaccttt cagaaatcag agccaccgcc ttagcttttc tgtaaagaac attattatat
     8281 cataatcaca caagaatccg tcaaatctta aactaatcag gcggcttttt tatgctctga
     8341 ctataggtct gaagagaaga tgctagatgt cttaggtggc tttccattta aactacgagg
     8401 tcttctttct cacagagtat agccccctct tttttcagct actgtttcgg aggcaagctg
     8461 gcatttcgtc taaattgctt ttgtttttcc ctgagcattc gaaaaaatcc tttatttcta
     8521 cctgacatat cactaaaaga gggtcctgtg accctctttt atagctatct gttagagaga
     8581 tatgcaattg ttagtcttgt tttttcttca agcctaggac acctgcgcta gcaatgacgc
     8641 tgagagctgc aagggtgaaa aatgggtgat ttgcctcccc cgtagctggt agcgtgccct
     8701 tttgagctgc tggagccgct gatttgtttg gtgctgactg aggagctggt gcctttggac
     8761 tagctggctg ctctgaagat tttggtgcct gtggagcagg ggattgctcc ggtgcctttg
     8821 gagtctctgg ttcttttggt gcttgtggtt gctctttttt ctccggtgtt tctggagcct
     8881 ttggcacttc tggcaccttt tgtgattccc cttgttgacc tggcactcct tgtggcccag
     8941 tatcaccttt tggaccttgt tgacctggtg cgccttgtgg gccggtgtcg ccttttggtc
     9001 cttgttgacc tggtgcgcct tgtgggccgg tatcaccctt tggtccttga agtccctgtt
     9061 cgccttgtgg cccagtgtcg ccttttggtc ctggttgacc tggctctcct tgcgggccag
     9121 tatcaccttt tggcccttgt tgacctggtg caccttgtgg gccggtatca ccctttggtc
     9181 cttgaagtcc ctgttcgcct tgtggcccag tatcaccttt tggcccttgt tggcctggcg
     9241 ctccttgagg accggtgtcg ccttttggtc ctgggagacc tggttcacct tgtgggccga
     9301 tgtcaccctt tggaccttgt tgacctggct ctccttgtgg cccagtatca ccttttggcc
     9361 cttgttggcc tggttttcct tctggtccct gtgggcctat tggtccacgc tcaccaactg
     9421 gtccgcgttc ccctcgaagg ccttgaggtc ctgcgggacc cattggacct tgaggtcctg
     9481 gtatccctaa tgaatctttc tcatacaatt tgtataattg ctctgattgg cctgtcgatt
     9541 tttttaaaaa ttgctccact cgccatagat atcttaaaac attttctagc attcgaccat
     9601 tgttataatg tgtcgaagtt tcccagtcac ttgagctacc agaaccagga ttaagtattt
     9661 ctttttttat gaactgttga aagaaatatc cttgattata catagaagga tatgtaaagt
     9721 cttctgccct tacatcattt ccaatcccta agctagctat ggttgctagg gcgacaactg
     9781 ctgagcagat accgtacttc tgaacaagcc tgatacttgt tttcttgttt ctcatgttta
     9841 tctcctttta gtttagaaat gttaacgatt tctaatcttt tttcttccaa agaaaatctt
     9901 aacatgacgc ttgcgggctg tgaatatgtt ttggggaatt cgcttccgta gtttcgtttt
     9961 tttctaatca aagggtcaat tgtctgacgc tagtgtcttt tggcattggc ctttagctta
    10021 ggaagactgc ctatgttagc aagcttttca ttagcttatc cgttttgata aagggtaagc
    10081 gacgaggata atctgacttt gtcttttgct tttgttagat tttttaatgt ttttttgatg
    10141 tctgatgact tttaaaaaaa gccttctttt gataggcaag cttaaaaggc ctaggcaaaa
    10201 gcccagaccc ttgctgctat tatctgttat tgtggaaagc taccgctctt tggcactgtc
    10261 atgcttaaaa attgcgactt gagctattgt aaccatagcg ctcaaggaaa tcctgacgaa
    10321 actctaaaag gttatcgtcc aagatagctt gacgcacctg cttcatgagg tttactaaga
    10381 agtataggtt atggtaactg gtcaagcgca tgccaaaggt ctcatcagcc tttaagagat
    10441 gacgcaggta agcacgtgtg taatgctgac aggtgtagca gtcacaatga tggtcaagtg
    10501 gggtaaagtc ctctgcaaac ttagcatttt tcacaacgag acggccctcg ctggtcatgc
    10561 aggtgccatt gcgagcgata cgggttggca ggacgcagtc aaacatgtca accccacgaa
    10621 tcaccccatc aatcaggcta tcaggtgcac ctacccccat caggtagcgt ggcttatttt
    10681 caggtaaaag tggcgttgta aaatcaagga cagcattcat ctcagcatgg ctctcaccaa
    10741 ctgccaagcc accgatagaa tagcccggaa aatccatgct cacaaggtcc gcagcagatt
    10801 gacgacgcag gtcctcaaag ccagctccct gcacgatacc aaagaggcct tgatcatgag
    10861 gacggcggtg agccttcaag ccacgctctg cccaacgact ggtgcgctca atggattttt
    10921 tcacataatc atagggctgg taaaattgcg ggcactcatc aaagctcatc ataatgtcag
    10981 accctaggtt attttgaatg gagatcgctt tctctggtga taaaaacatc tttgagccat
    11041 tcaggtgatt tttaaaggtc accccctcct cagtgatgtt tctggagtct gccaaggaat
    11101 aaacctgaaa gccgcctgag tctgtcagaa ttgcctgatc ccagttcata aatttgtgaa
    11161 ggccgcctgc acgcgcaatc agctcatctc ctggtcgtag ccataggtga taggtatttg
    11221 acaaaataat gcctgaccca atctccttga gctcctcagg agactgtgtc ttaaccgtcg
    11281 cctgtgtccc taccggcata aacatgggcg tcggaaaggt cccatgcggg gtaataatct
    11341 caccgagacg agcacctgta tgcttttcct ttttgatcaa acgataagta atagggtaat
    11401 tagtcattgt ttcttttttc cttgctatca agataaacag tcttgagcgt tttgcatacc
    11461 acttacaaag cacttagtca agcggtatgg gcttgtttag agccctatca ttttatcaaa
    11521 aaatctctga cttgtcatgc cttcaaagag acaagatccc gaagcaatgg cacgacagac
    11581 gcatgaagga gttttagcaa gaaaagaaag ctttctgtcg ttcaatgttc agctatttca
    11641 agtatatgtc ttatctttta taaactttac tacagaaaaa tcgttgaaaa tgtttgcttt
    11701 actctatact atcattcaga aatagctgtt tcgcgcgttt gtcgtgagca aggacggtat
    11761 gggtatcact ggctcctaga atatggtata atgtaccaaa ggagttgtac gatgtcaatt
    11821 agagaaataa aacgtgaagc tagacagact ttaaagggac taaaggggaa atacctctta
    11881 tttttagtac cgataatctt atctattttt tactcaggaa ttgaggttca tcagacctat
    11941 gtgaccactc aggggattga ggtatcagtc ggggcaagct actttccttt gattgttctg
    12001 ataatgctga cggtctttac cttatcagca gcctatacca tgctagatgt tatccgctac
    12061 tatcgtcgtg aggtctcttt ttcagaggca acgatagctt tttctggaaa cttgtttggc
    12121 aaggtccttg ttttgttgat catcaaaggg ctcctattta tcctatggtc tttgatttgg
    12181 attgttggct tggttattct aacgattagc tctgcggcat tactgacaag ctacaatact
    12241 ggtgctgctg tgatgactcc aatcatcttt atggttattg gttttgtgat ttttattatc
    12301 gggcttattg tttatatgaa tcgttattgt gcttacagca tggctgagta cattctctat
    12361 gacaaggtca aggaaggcac ctatatgggt gctattacgg caatcgaaga gagcaaggac
    12421 atgatctcag gctataaagg aaagtatttt ttactacacc ttagctttat tggctggttt
    12481 atcctagtaa tcttgtcttt tggcttgatc tatatctacg tactgcctta ttacaccact
    12541 gctgatgtga ccttttacca ccatttaaag cacattcacg atgaaacaga gctgccgata
    12601 gatgctgaaa ggcttactat cacaggttca aaagaagccc catctgctat tagctagcct
    12661 taacgatatg cctctatgtc tctcatgacc ttgttcagag tagacataga ggttttttgc
    12721 atgacctttg ataacttttt tatagtaaaa aagaggagcc catcagttgc ctatccaaag
    12781 ctagatgaca catctaacgg ttggaaggct tgcttacagg ccctctttta gcaatgttag
    12841 cccaagacta tcctaaagct gctgaaaagc tcctcggtct aaggcatagg cagtcgtcca
    12901 atggctctca cgatagtaaa taaagagctg gctatctaat agctcatcaa ttgaggctgc
    12961 tgttggcaga cctgctaggt caatgaaata atcccctgga agaagctgtt gtagcttttc
    13021 cattaaggcg gtattaacag cggtctttgc tgctggtaat tgactagaga ttgataagcc
    13081 ttcaaaggtc tttaaatcta tgttttctga ctctaaagct gattttaagg ctgatttgat
    13141 caagtctagg ctgtattcag catctaaggc ttcatcgcct gatgagaggc tattcatcgc
    13201 caatacatac aaagggcctg ctgccttatc ctgataggta atgacaagtt gatggttcag
    13261 caaatcagct aagtcatcat aagtaccagt gttctcaaga gtaatgtaat aagtccctgt
    13321 gagccctaag tccttgattg tctctaaaat cttgccttgg attgcttgat ttttttcagt
    13381 tgttgccgct gttagaccac tatttgtaat agcaaagctc tcaatctctt tggtagctgt
    13441 attggtctct tttagaatgg ttagaatact atctttaagc gctagaatat catttctaac
    13501 cggtgcttca atagggctag agatgtcttc aaagaaacga taagcagaac cgctgacaaa
    13561 tttattggcc tgtccgctgc tttttccata ggtgtctaag gcagttattc taacaaatcg
    13621 acctgttgtt ggtgtaaagc tgactgtttt tagctcagta ttttgcttcc aatcagtgct
    13681 atcgacaacc gttgtccaga ccttaccgtc tgagctgatg tcgacctttg cagaatggat
    13741 cataccatta acacctcctg ggagataggc aatagcagag aagtttttat cgtccttaaa
    13801 ctcaacagta tatgacttgt cctcagtaac ctgattaaat aaggtatgcc attgggtggc
    13861 catatctcta ccatctacca tatgcttgcc agacctgcct gattgctcat tagcataggt
    13921 caccgcctga atatcatcaa ttgagatgta gtgcattgta ggatcagtgc tgtctgcggt
    13981 aaaggtatag gtaacgctgt cacttgctag actggtgcca tgagcccgat agcgagcaag
    14041 aactgtgaca gtgtcattga agcgctctgt gccatcataa gcctgccaag actggccatt
    14101 atccagactg acctccaaat gttcaatagc accaatcaag cgattttcca agtcattgcc
    14161 ataaaggctg ctgttggtcg gtgctgctgc ctttgtcagg ttaatcctgt aggtagcaga
    14221 taccgcgtca aagccaacta aaataccgtc ctctatatta agcttggcca aaaggtcatc
    14281 actaaaaacg ataaccttgt ccttggtttc aagccatgtt ttcccattat caatagaata
    14341 gcggactgtc aaatctgtat cctgataatt ctcatgcaaa cgaagggtct tgtcatcaaa
    14401 gctaaagctt gctgtttcga ttggattgcc cgttaggata tagttggcga taattctaac
    14461 ctcattagat tggagcactt ccttatcagt tgctgttttg gctgcgatta gagcgttata
    14521 gctcagtaaa tctagctcag ccttagctgc ttgatcgctg atattaggcg tgatacgctt
    14581 gatagcctct accatgacct gtggatagta ggtgtaagct gcaatgacac gctttcctaa
    14641 gtccagccaa tcctgatctg ttttttggcc attttttgca taggcctcta tcaagccatc
    14701 gtaagtatct agattaagct ctagtacatc taaagccttg ctgtaggcct caatctgttg
    14761 atcactgcca gcctcgtaga cattagcgat gagattataa taaagcgatt ccttgaactt
    14821 atcgtattgg tttaaggctg cttgcgccag cagcatatag ctagcgtttt tatgaatgtc
    14881 attgtaggat tttaggcccc agccaagcaa gagcctagcc tctgttgctg ttgtggttcc
    14941 ccaacgagaa taagagattg cccagcgatt accataaaca ttgtctctaa tatcccaaat
    15001 cccgttgccc tgatcatctt gacggtaaac caaataagcc tcgtggtcat tttggtaaat
    15061 attgaccgct ggaataccaa agacctcatt gactgctaca cctaaatttg ataatcccca
    15121 gcaaacagcc cctttttcca tcagcatcca gatccggtga cggttgtcat aagtaacatt
    15181 aaaggcatcg tcattgaggg tgccaacgag ctgatatttt tctgtccatt gagcttgatt
    15241 gtcagcgctg cgcatgtctg cgccaccgta gccgatgttt ttgtatttcg tataagagta
    15301 gccactggta tagctagcaa ccttatctcc atatttttgt tcggcgtaat gatgcagcca
    15361 gagaatttcc tcatcatcta ttttggcgtc cataacagca cgcaccaact ccatattgta
    15421 gttggcgaat tcttctttcc tcaagaattc gttgtctcga tacaattctt taaaggcttg
    15481 atatttcagc accgggtcag aagcaaggta ggtgccacca tagttaacca caaaggattt
    15541 gatctccttg cagtaggcaa cagcagttgc cagcatcatt tttttgtaga catagccatt
    15601 tcccttgtcc tccaaatctg ccttattagt agcataaagg tctcctaagg cgttcaaggt
    15661 ttttagggta gagccgttaa acatcgagcc tgcctctaaa aacagtgaca gagcgtcctc
    15721 atctgacaat agccaatcaa gagcgacctt gaccttttca tttttcttga cagcagattg
    15781 aatggtgtgg tagccgacac gattgacaaa ttcgcgctca agcactaatg ccaaattgtc
    15841 tggattatca taattatctg tgacactatt cttgctgaga agggcatcat actcttcagt
    15901 tgtctttagc ctgtcataag acacctcgct tgataaatca taatctgtct tgagcaacct
    15961 gagatccgca taaacagagt gatcattacc gttatttttt agtgaatttg caattagctt
    16021 tacatattta gcacctgtaa tatctagatc aacataaaca gcctcactgg ttccggttac
    16081 tgtaccagtt gtcaccaggc tttcccaact ttttccgtcc ttagacttat agatgttaaa
    16141 gctaacacca tcgtccttac cacgtctact atagtcaact cctaggtagg ctgatagacg
    16201 cgtgtattca ttggagtatt gttcaacatc ataataaagc tgtgaaggag catgcactgc
    16261 aattccctta tcaaatgcaa gcacctcgcc atcaactact agagtaatgg tgccaccggc
    16321 agggtttttg tcctgtaaaa agctgccatg cccaaccttg gacgggttga cacgtgtctc
    16381 atctgataag tagatatagt ccttagcttc agtcttattg gtggtctcta ctgcttgtga
    16441 tacttctgtc tgctcctgct ttgtggtctc ttcggcagaa gcttcggtag cttgctctgc
    16501 tgcggctact tgactcttag agtcagttgt ttctgtagtg gcagtaccta ttactactgg
    16561 cagcgtttct gaggagccct cagctgctgt gtcttgcgca gcggttgctg attggtcagc
    16621 tgcttgttga tcaaccgctt cttgtgcttc taacgtggtt gctatggctg cactagctgt
    16681 tacttgctgc tcatcagcag aaacagttgt cagccctagt gttaaaaata aggttgcaac
    16741 caacacagag gctgcacctg ttttaaaggt tttaatggca aagcgctgct taccatcagt
    16801 ataaggtttg aacatggtgt cttctccttt aaaaataaga tatttaagca aaataaagac
    16861 tgaccaccaa ccactacagt tgataatcag tccaacaaag atatcgtact ataggaaatt
    16921 aattaaaggg ggaaaatcat cgcctacagt taatttgatt ctttgcgtct tgacacaata
    16981 gcaagctggc ctgcacaagc aataactgca agagctgctg ctgtaaagaa tggattagct
    17041 gtatcagcag ttgccggaag cacttgctgc ttatcagctg ctttcttgtc ctccttctta
    17101 gcttcaggct tagattctgg tttaggctct ggcttaacct caggatctga tggttttact
    17161 ggatccgctg ggtcgattgg atcgaccggg tctaccggat ccactgggtc taccggatcc
    17221 actgggtcta ctgggtctac tgggtctact ggatccactg ggtctaccgg atccactggg
    17281 tctaccggat ctactgggtc taccggatcc actgggtcta ctggatctac tggatcgacc
    17341 ggtttagcaa ccaaggctgc cttggcatct gagagggatt tcttagcatt taacacctta
    17401 accaagctgt tagtaatagc tgtcggttct gtctcctgag cataagctgt ctcacccgct
    17461 gctgcgacct ccttagcctt agctagctgg tctgtatagg cttgagcaga agctgctgta
    17521 tatggagata ggtctagatt ttctccgata agagcattta attggtctaa agcagaacgc
    17581 aattttgcct ttccttcttc ggcaatcgca gcctttacct ttaaaatagt atcaacaact
    17641 gaatttgttt ctgtagtgta gcgctctagc tcataaaggg aaatgtcttt tctctcttta
    17701 tccttgttaa cagttctata gaaggtacct gctgcttcaa tggccttatt gtacaattcc
    17761 ttcaaagact ctgatgtcaa agcaagattt ggattttctc ggtaaagctc taacagctta
    17821 gccaaggctt gatctaaggc ttcatgcgct acagcagtct taagcgtcgt aagagcttgc
    17881 gttaaatcag tcgcagcctt atcaacatct ccttgtgaag gaccaaatga attttgaagc
    17941 ttagctgccg ctgcaagctt ttgcacaaga ccgtcatacg cttctttagg atactctttg
    18001 ccatctgtta taaaaggtgt agcttgatta atagcttcat ttaaagcatt aagattaaca
    18061 agactagtaa tagcggaatc aatagtagta acagattgat ctactgtatt ttgatcaggg
    18121 tcactgttta aataggtctt accaatagta accgctgatt gcaaggcttg cagtgattca
    18181 tcagaatacg ttccttcagg ctggctgagt tttagcttag cctcctctaa cgacttcctt
    18241 aactcagttt tattgctgtt ggaatttttt agtttaaatg tgaagagctt tttggtatca
    18301 tttttcccat agaataccca agctttaata gtataagatc cccccggtac agcatatgta
    18361 ggcgaagcta acatttcatc agttaaaaag gaagtacccg cagcattgta aaagtcaaac
    18421 catattttta ctccaggggt atcaattcct cttgaaccat ctccattcga aataaagtca
    18481 aaagtatctc catcattaac agtcccatta ctacctttac gagtaaccgt aatttgactc
    18541 ataagatctg agatagtaat tggttctcct aattcaactg tatattcttg tggaatatct
    18601 atgtgccagt tcagatgttg acctgtccca ttattttcaa atgcactagc agtagtcgtt
    18661 tccgccccta ctgttaaagc gctatcaata ttatccgaca aggcaaccaa tcctgtgctg
    18721 aaaactaatc caacaagacc acagccctta agacaccgtt tcgtgaattt cttcattctt
    18781 ctttttcctt ttctagagcc ctagcaggct cgaacaatag caatatgtgt catagggcag
    18841 ctgctatcac tagtagctgc cactttgata ttagcctgat tgtgacactc aaatatcact
    18901 tataatttac aaaaaatttt aagaaaagtc aatatacaaa cggtttttgt taaatttttt
    18961 aaaaatataa caaaaaacaa gcacgccaat ctggtctata acagttttta ttgtcaatag
    19021 tgatcgctaa agggtttttc agccaacaaa aaaagagtga gtccctaact ctctcttcta
    19081 gactttgtgc catatcatca gctacacgaa cagccaagat caaaaaggcc agctctcaat
    19141 agtctgtgtc cttaccctgc ttcgtctgac agctagggca aacaccatag gctataactg
    19201 gaatacgggt gaccttatag cctgtttgct ggtgtgcttc cttagcgata tccatcacat
    19261 ctacgtccat aaaatcagcg attgtcccgc aaacctcaca aaccacattg acatgctgat
    19321 gtcccataaa gtcataatag gtcgtcaaat cattactaat tttcagctcg gatacaaagc
    19381 cctcatcaac gagaaccttc aaattattat acaccgtagc aaggctcata ttagggtatt
    19441 gaggctgtaa atcacgatag attttatctg cgctggggtg ctcagtggac tgaatcatgt
    19501 aagaaatgat cgccttacgc gtctcggtaa tacgaatatg cttgtcacgt agatgctcta
    19561 ggacattttc ataggcattt agagcttgct gatgtgaatg aatgtccaag cttacaacct
    19621 cctccttttg taactatggc actaactagc aggaatcttg atcctgcttg ctgattagcc
    19681 gtaaatagtc aatcttgata cagcgattca taacaatgtc agctttgcct gctgatcgca
    19741 aaagctcctc agcttcttgg ctatacaagc caagctgtgc ccaaaagacc tgaccctgac
    19801 aagctaaaaa gtcctgagca acctgaggca aatactcact tcgtcgaaag acattggcaa
    19861 tatctacctt aaaaggaata gccgcaaggc tagcataaac gacctctcct aaaacagact
    19921 gacctgccag cctaggattg acagggacaa tccgatagcc cttagcctgc ataaacctag
    19981 ccacatcata agcagcagtg gtttgacgat cagataagcc aaccactgca atggtcttgg
    20041 aagattcaag ataagaggtg atagtctcat cagagggatt ttgaaatgta tcaatcatca
    20101 tttacttcct ttttatcaag cacacccaat agcaaatcaa caacaggaaa agacaatcgc
    20161 tgccggtatg acatagccaa ccatctggct accaagctca aggaaaaccc tccttagcat
    20221 gacatgccct gctgtttttt tctcttcatt atagcataag tttttaaaat gcggaacaca
    20281 aggaataaca gcagccacac caagcaggct gccacttaac accactgcta atctagtcta
    20341 cttggcctca taccagctct tgccggcact ttcgtctaca cgcagcggaa ctgccaggct
    20401 gacagctgat tccatcgttt ctttgaccag cgctttaaca gccgctagct catgattagg
    20461 cacctcaagc acaatctcat catgcacctg aagcagcatt ttggtctcaa agccaccagc
    20521 tactagggct tggtcaagat ttatcatcgc aattttgaga atatcggctg cactgccttg
    20581 aatgggcgaa ttaatggctg tacgctctgc aaaggagcga acgttgaact gacgagaatt
    20641 gatatctggc aattgacgac ggcgcttaaa gagcgtctca acatagccct tatccttggc
    20701 ttcacgcaca accctttcca tgtaagcctt gataccaggg tagcgctcaa agtaggtgtc
    20761 aatataagcc ttggcctgtt ttcttggaat tccaaggtta ttagacaagc caaagtcaga
    20821 aatcccatac acaatgccaa agttaacagc cttagcattc cgacgatcat tggcagtgac
    20881 gtcctctggc ttttcaatgc caaagacacg cattgccgtt gaggtatgga tatccgctcc
    20941 ctccttaaaa gcagcaatca aatgctcatc tcctgaaata tgtgctaaaa cacgcaattc
    21001 aatttgcgaa taatccgagc taagcaaaac agcatcatca tgagatggag taaaggcctt
    21061 acgaatcaag cgcccctgct ccagacgaat cgggatattt tgcaggttag gatcaacact
    21121 ggaaagtcgg cctgtctggg ttaaatcctg taaatagcgg gtgtggatcc tgccatcagc
    21181 catgatgtaa tcctgcagtc caatcacata ggttgattgc agcttagtaa tttgacgata
    21241 gtccaagatc ttagccacga ttggcgcaat tggcgctaag cgctccaaga catcaacagc
    21301 cgttgaatag cctgtcttgg ttttctttgt caaatgaaga gggagctgca ttttctcaaa
    21361 gagtatcact cctagctgct tgggagaatt aatattaaag acctcaccag ccatttcata
    21421 gatttcctgt gtcagttcct caatgaccac cttattttgc tctgccattt cctgcaggct
    21481 atcttgattg acagcaatgc cttcgatttc cattttcgca aggacattgg caagcggcag
    21541 ttcaatgtca gtgtagagat cagcctgctc atgctctgcc agcttatcaa gcatgactgg
    21601 tctactatcc agcaagacct gaaccttacg cgccagatgt cctaacaaaa cagccttgtc
    21661 aggcacagca cgcttgaccc ccttaccata gacaacctca tctgtatcca gtgatatagt
    21721 ggtataaaga cgtgccagag tagccatctc attgtcctct acagttgaca agaggtaatt
    21781 agctaagcgg gcatcatagc tggcagccgg caaatcaagc cccagatgac taagcagaac
    21841 cttactgcgc ttaaaatcat aggtagcaat cggctgctca agaacctttt taaagagctt
    21901 tgtagtgagg agactaatat ctgctgaagc ataaatctgg ccttggttgc cccaagcaaa
    21961 gccaatcagc tcctcgcggt gataattatc cctcaaagct tcaaaataaa acaccgtatc
    22021 gtctgaaaac atgtccgctc ttatgtcagt aacttcctga taagcaatct cagctaccgg
    22081 ctcctgtggc aactgactag ctaaggcatt ttttagttga acaaaatcca tctcatcata
    22141 aaattgtgac aagcgatcta gatctggacc ctgatagaca atatcctcca atccaatcgt
    22201 aatcggagcg ctagtgttga tagtagcaag tgtctttgag aggaaggcct gctccttatc
    22261 atgaagcagg ttttccttca tttttgaagg cttgaagcta tcaatatgct cgtaaatccc
    22321 ctccaagctt ccatattcgt gcaggagctt tagacctgtt ttttccccaa ttttggtcac
    22381 tcctggaata ttatcagact tgtctcccat gagcgctttc aagtcaatga attgctctgg
    22441 cgtaagcccc attttgtcca taaggtaggc tggggtaaac tcttcaaatt cagcaactcc
    22501 ttttttagaa atctcaacaa cggtatttgc atctgtcagc tgaatcaaat ccttgtcacc
    22561 actgacaata gtcacatcaa aaggaatctc tgtacgctct gccattttat caagcgttcc
    22621 gataatatcg tctgcctcgt aatgctctag ctcataaaag gcaataccaa gcgctcccag
    22681 catatcacga atataaggaa actgctcccg aaattcatca ggggtcttgg cacgtcctgc
    22741 cttgtaatca gcaaaaagct ctgtccgaaa ggttgtttta cccgcgtcaa aggccaccaa
    22801 gacatgcgtc ggctgaacac gcttcatcat gtggtctagc atcaaatgaa agccataaat
    22861 cgcattagtg tgaagaccgc tgtgattttt aaagcggtca atctggttat agagggcaaa
    22921 aaaggcacga aaggccactg aggagccatc aatcaaaagt aatttattct tgttttccat
    22981 gcctttatta taccacacag tgacctgctt tgctctgacc agctacgctt tttgcaagca
    23041 ctagcaggta aagcagcata cccgtagctt gatcaaaaga tccaagctgc ttgaaggaag
    23101 ataaatgact gcttttgctt tatcatcaag acatttctac caaaaaagag actgagataa
    23161 aaagagtgac actttagaga gtcttaacta atatcctttg ttatctaatt cattaacaaa
    23221 cgaacaggcc tagttttcaa aacctcagaa aactaaacct gttcatttgt tctatttgaa
    23281 gtcagacttt gtctcaatct ccaaattgat gacatcatct gctatgactt tcctaagctg
    23341 atatggacgg aaagccttct gcaaaatcca tgattagtct aggctacatt tgagcgagcg
    23401 gccttatgac tgagtccatt tggccacctt atcagcatgg ctagccaccc atttcttggc
    23461 tgcggcttct ggtgtcatgc cctgattgat gtcaagcata acagcctcca tatcctcttt
    23521 ttcccaatgg aagtgatcaa caatcctatg aacagctggc aggtcggcct ttaagccccg
    23581 acgtgcaatg gtattgatat tttcctttga gccaaaggtt ttctttggat ctgccaggta
    23641 tttcaaatcg tacttagcaa acatccaatg aggagaccaa gccgtcacaa cgatcggctc
    23701 ctttttcttg accgcctgat caagtgaggt ggtcatagca cctgtcgaag cagcaacgag
    23761 ctcccaatct gccaagttgg aataggcctt ttgcgtctta tcagcagcag tcataatacc
    23821 agctcccggt tcaatcccaa taatctgttg attggcttga tccgaaagct cctctatgct
    23881 gttcacatcg ctcatatagg ctggcacagc gagtcctagc tttgttccct tcagattagg
    23941 accaagatta tccagcttat cctgatactt ttggtactgc tgctgatggg tcactggtaa
    24001 ccaggcactt gttgaaaagt ctgcatcgcc atttgcgatg gtttgccaca tcacagcatt
    24061 atccagtggt gtcaaggtta cctgataacc ctcatctctt aagacctgag cgataacatg
    24121 ggtagaagcc acctcagaat cccactgcac ataagcaatg gtcaccttct gccccttgtc
    24181 tgctgagctt gataacatcg cagcaaagcc acgccccaaa gctgacaaca aaaagacagc
    24241 taaagcagct agaccaagcc atttcttggt ttttccagtc tgcgttcttt cttgcggctt
    24301 accgttaaaa tgctgagtca tacgatccaa aataatcgcc aagataacaa gggccaaacc
    24361 actaacaaag ccacgcccaa tatcagcatg ctgcaaggcc gataggacct cacgtccaag
    24421 acctggagca ccaatcattg agcctgtcac aaccattgat agggccaaca tcatggtctg
    24481 attaacacct gccatcatcg tatgctttgc caagggtaat tcgaccttca gtaatttttg
    24541 tttaggggtt gacccaaagg catctgaagc ttcaaccaat tctgtcggaa tatgacgaag
    24601 cgctaaattg gtaaaacgaa cagtcggcgg caaggcaaag ataaccgacg caaagacgcc
    24661 agggaccata ccaatgccaa aaaaggcgac agccggaatc aaataaacaa aggctggcat
    24721 ggtctgcata aggtccagca ttggattaat cacctggtga acaatcttat ttttagccat
    24781 ccaaatgccc aagggaatac caagcaagac agagatgagg cttgctacca aaaccagcgt
    24841 aaaggtattg atcagctctg cccacaggcc ttggttatag acaaataaca ggcccaggag
    24901 ggtaaagatc ggcaaaggcc atttttttct tgccaagaaa aacatcgcac aggtaaccaa
    24961 tagcataaac agtaacggat tgataaacaa aagggtctgc gtgatccaat ccatcaaagc
    25021 attgcccaca agctgcagca gatcaaagaa gcctgaaaag gtttttgtca gccactcagt
    25081 tagttgctca accagctgtg ccactggtag agttgtttgt aataggtttt ccaaaataca
    25141 gtctctccat tctaattaag gtcgtcatct ggaatattag ccaaggcttc aaggacacgc
    25201 ccacgaataa taacccctaa caagcggtgc tgctcatctg tcactgcaat tggcgcagaa
    25261 gagtcataaa tcaagggcaa aatatccgta ataacagtat cctttgagac cgttctgaca
    25321 ttacgatcaa taacctctga caaggggagc tttttctgac gtgcttcaat cgctccgtct
    25381 gctgttaggc ttcctattag ctgacgacga cgattggttg ccatgagcat agacacctcc
    25441 tcattgtgca tacgattcaa agccacctgc ggaccgtcca gatcaaccgt tgttgtgata
    25501 ggcttaatca taatatgctg agcagtcagc acctttgagc ggtcaacgtc ctctacaaat
    25561 tcacgaacaa aatcattagc cggattggtt agaatatcct cacccgtccc aatctgcatg
    25621 atctgaccgt ccttcatcaa ggcaatacga tcaccaatac gcagagcctc attcaagtcg
    25681 tgactgataa aaataatggt ctgcttcatc gtctcctgta attctagcag ctcatcttgc
    25741 atgtcacgac gaatcaaggg atctaaggca gaaaaagcct cgtccatcag caaaatctta
    25801 gggctgtttg ccaaggcacg cgccaagcca acacgctgct gcatgccacc agacaattga
    25861 tcagggtatt ggtccctgac ctcaagaagc cctgactgat caagcgcacg ctttgcaatc
    25921 tctcgacgct cctgctttgg taccccacgc agctccaagc caaactctgt gttttccaaa
    25981 atcgtcttgt gtggaaaaag agcaaagctt tgaaaaacca tattcatatc atgcctgcga
    26041 acttctctga gctgatccac agacagttta gaaatatccc ttccctctaa taaaatagag
    26101 cctgctgagg gctcaattaa tcgattaagc atacgaacaa gcgttgattt gccgctgcct
    26161 gaaaggccca tgatcacaaa aatctcgcct tcctgaacct caaagctggc atcatagacc
    26221 ccgacagtaa ctcctgtctt tttaaaaata gcgctcttac ttttaccagc cttgatcatt
    26281 tcaagagctg ctttttgttt tttgccaaac aatttactca aatgcctgac ctctaaaata
    26341 gttcccattc ttttcctctc ttgttctctt cctcgattaa agctaaatta gcttaataga
    26401 tttctaaaag tgccaccaca attttaaaat aatgaggtca ctttttgctt aaaaaaaaga
    26461 gtctgcctaa acagaacaca ttaattatat aatatatggt cactttttgt caagctggac
    26521 gcttgctacc caagtatcag gatcgtccta agcagtgata tcactagtca accaagcact
    26581 taacagccct gaacagacca cagcaagcag gcctttctga cacttagcgc cttgagagct
    26641 tacccagcag cctcctctag ctgacttgat tgacctatct gactcttgtc ctgcaaccaa
    26701 accaatgctt agactgccaa gcaagctccc aatagcaata agatctgcta agcaaagcgt
    26761 tagcttgctt tgaccatagc tgctagtcat gtctaatagc actctagata aatcaaaagc
    26821 cccacctagc aaggctagat gaggcaaaat aggtttagag aagggcttta aactgaatat
    26881 ttgagtcttc caagaagcag tcgtcaaagc cacgtgggtg atgatactcg atgcgatcct
    26941 gatcctgtgg ataggtgtat ttgccaccaa cctcccaaat gaatggatgg aattggtatt
    27001 gcaagcgctc cttacgcatc ttccaaagct ctaggatttc atcagttgag gccatgaagt
    27061 ttgaccagat atcatagtga accggaatga caaccttggc gcggagattt tctgccatac
    27121 gaagtaggtc aacagaggtc atcttatcct gaataccgat tggattttca ccataattgt
    27181 tcaagacaac atcaatatcg tagtcacgtc catgcttagc aaaatagttt gagaagtggg
    27241 agtctgcacc atgatagatg gttcctcctg gtgtttcaaa aatgtagtta acggttttgc
    27301 gagctaactc ttcgtcagtc actggaagtc ctgctagctc gccaccattt tcctcagcgc
    27361 cagcaactgg taaggtaacg atacaggtac ggtcaaagga ttcaacagca gtaaccttga
    27421 tatccttgaa tgcaaagcta tcgcctggtt ttaccacgat gatacgatcc tttggaacac
    27481 cccagctctc ccaaatcttg ccgcactcat aagggccaac aaatttgaca tggtcaagct
    27541 ttggattgtt gataatggct gctgcagtat tgatatcaat gtggtcacta tgataatgag
    27601 acaccaagta atagtctaac tcattaatca taaagggatc aataaccatt ggctgagctc
    27661 ttagatttgg ttgtagcttg cgaacccctg ccatattggc catttggtga ccacgaacca
    27721 tgtcttttac ttttttagtt gcctttccac gattggacca taggtccatg acaacattgg
    27781 caccacccgg tgttttgatc cagataccgc agttacctag ccaccacata gagaaatttc
    27841 cttcaggcac tacctcttct tcaatttctt cgtttagcca ggttccccat tctgggaagg
    27901 tgctaagaat ccatgattca cgagttatat cttgtacttt agccattatg tttcctccaa
    27961 aatgaatttt tatctatact ctaagtatag accttcttta ttctcataaa aagaccaagt
    28021 gtcacacact cttgtgttca aaactggact gaattttggc tcaaaataaa ctaaaagccc
    28081 cagccttctc ctaaaccaat agacagctga ggggtcctta tcaataggca agctagtagc
    28141 ttacaataat tcgtgatgaa tgagcttttc aatttttgtt ttcaaggcat agcggtcagc
    28201 atcgtcctta acaatggtct cgatcgcctt ttctagctca agggaaaaac gagagctatc
    28261 actcaagcgc ccctgctttg aaaaacggat caatctaata atgtcatcat cgctcaaaat
    28321 aggattgaca atcagtacgg gaacaagagc ctccagtgcg tctgttgttg ataccacaat
    28381 gtcaacagac atcaaatcaa agacactctg gtattgctct gttgtaaaga cagcctcgat
    28441 ttgacaattg ggcaaataac gctggcactg cttcaacagc agcttttgaa tcccaatgcc
    28501 atcatctgaa acgataacaa gcttggtctt gtcccagtca gcatgactat ggcgcagctc
    28561 tcctcccaga tgaatcgtta gataagccac gtcatcatct gttagacgga tctgccaagc
    28621 ctgctctagg attacagcac aggattgagc catagcaaag agctcctcgt atttttcctt
    28681 aatatggtct gttaaaggat tgatcgaaaa aatcccatag gcctttcgat aaacaagggc
    28741 cttgcaatgc ctggtcagct gtctaagcaa gtcctttttg tgggtaaaat gcagctgata
    28801 gcgcagctcc agctgatcga taaaatcacc aatagtggct cgcatctgct cataatcctg
    28861 actttcaaca tggtgatcct gatcttttct aaaggatagc atcagcatgg ctatcatgcc
    28921 tacctcaatg tcatctaaat gcagcttgaa attgtggtaa agctcactag ccaatgcctt
    28981 agcaatctgg tattccttgc gcttccaaat caggttaaaa tcccttttaa gcgctgtttt
    29041 agtttccgaa tgcaattgca tgttgcgata gctaagcagg ataaaaggaa gaatttgcag
    29101 cataaactga ctatcctgaa tattaattgt tttgcctagg ctagcctgag acaaaaagag
    29161 gtattcgtga aaataatcca aaacctcctt tgaaaaataa gctgacaagc cttgtgtctc
    29221 agaaagctta tgatcaaaaa gctcaataaa gctgctattg cctccctgat aaacacctgc
    29281 caataccttg taaaggtact gaatcaaagc catagggtga cagtcaaagt aatagccctt
    29341 ggccttggtg gcatgcagct gaatcttatt gttatagcta gacaattcct ctctcagttc
    29401 agcaaggtca tttaagatgg tatttctgga aacatcatta atcatcatga gcttatccag
    29461 tgtcacccgc tctgttgcca ctgcaatata aatcgctgat aagctcctgc gctcatcacc
    29521 cttcatgaca tagtgataat ctgccacttc attgaggagc tgttggcagg cagccttttg
    29581 ctcactattt agcaagatgc caacccgagg ataggagaca atttgagcaa catggctggg
    29641 cagcgcttcg ttaattttat ccaaatgata atagattttg cgccgcgact gacccaaggc
    29701 agctgaaatc gccatgactg tctcagcctc cttcaatcga atcagatatg acagcagatc
    29761 atagcttttt ttatccaaaa taatcacgtt catacctccc ttctataaaa catcactacc
    29821 acacagcctt atcagtttac cattttacct atctgtagga aagaatacta ggccaaagtc
    29881 aatttctaaa taggaaaaaa cgaacgatca ttagttttct gaagataaaa ttcctaatta
    29941 gttcgctttt ttcttttata attgtaatag ttgaattaat tattaaactt tgtctaaaat
    30001 aagaggcttt ttatcccaga ttgcaacaag ggttaacacc ttgaccttaa gcctagctaa
    30061 gcagctctca ctaagttact agctgctgcc ttaatgccgg ctaccttttt ggccataata
    30121 ggcatttgga ccatgctttc taaggtaatg cttgtccata atataggttg gagctggctc
    30181 cacacgagga ttgatttgtt ctgtcaggcg gttcatcttg gccacctctt cgagcaccac
    30241 tgagtgataa accgctaatt caggcgtctt gccccaagta aagggaccat gattgcgaac
    30301 aacaatacca ggcactgcca tcggatcaag accacgacta gcaaattcct ctaaaataac
    30361 cgtacccgtt tctttttcat aggctccatt aacctcatcg gcagttagag agcgagcaca
    30421 tggaatgggg ccataaaagt aatcagcatg agttgtccca taaaatggaa tatctcgccc
    30481 agcctgtgcc cagccaaccg cttctgttga gtgtgtgtgc acaatcccgc caacctctgg
    30541 ccatgccttg tataattgca catgggttgg caaatcagaa gaagggttca gctctccctc
    30601 aacaatagtg ccatctaagt ctgtaacgac catattttcc ggtgttaatt ggtcatagtc
    30661 aacgccgctt ggcttgatga cgatacgtcc cagctcacga cagacctctg agacattgcc
    30721 ccaggtaaat ttcaccagcc catgcagcgg tagggccttg ttggctgcac agacacgttc
    30781 acgcatttct tgtagccttt ttgccattag cttaaccccg ctttctcaat cagtggataa
    30841 aggaaatcct gtgcctcctt gatggcagct cttgtctcct ctacagtttc acagttttct
    30901 gaccacattt caatcaaaaa tggaccatga taatgcgttt tcttgagcac atcaaacatt
    30961 gcttcccaat caacacagcc ttgaccgaat ggcacatcac gaaattgccc tttagatgtt
    31021 tctgtcacag cataggtgtc ctttagatgc aaggcagcaa tagaccgatg cccattgtaa
    31081 aattcactcc agaggtcatt atgccaagca gagacattgc ccgtatctgg atagacaaag
    31141 agataagggg agtcaatttc tttttccaca gctaggtatt tctcaattga gttgataaaa
    31201 ggatcgtcca ttatttcaat ggctaaaata acctgagctt cctctgccca agtgcaggcc
    31261 tgtctgagat ttttgataaa gcgcgcacgc gtttcaggtg atttttcttc ataataaacg
    31321 tcatagccag ccaattgaat ggtacgcaca ccaagatcct gtgctagcac aatgcatttt
    31381 ttcattagct ctaatgatgt cgcttctgtt tctggattgc tagagccaag tggataacga
    31441 cgatgaccag agaagcaaat gcttgggata cgaacccctg tttcataaat agccttgaca
    31501 atgtctagtc gctcctgttt actccaatcc aagcgcgcta ggcgagcatc tgattcatcg
    31561 acagacattt ctacaaaatc aaagcctaat acctttgcaa attgcaagcg ttccagccaa
    31621 gtaaaatgct ttggcgttgc tttttcatat ataccaatag gacgcgccat attgttaccc
    31681 ccaaatgcgt cgaatctcgt ctttaaaggc acgtgccgct gctgcaggat cctctgcttc
    31741 agtgatacca cgacctgcaa taaaggtaaa gacattaacc ccttcaaaga gcttgagggt
    31801 attgatatct aagccacccg tcaccgatac acgaaagccc atgtcaatga gggctttgac
    31861 cttgttcaga tctttttcac cccatacttc accagcgagt agggcgtcac gtgattgatg
    31921 gtaaatcgcc tgtgaaatgc ctgcatctag ccacaattgt gcctgttcat aggtccaatc
    31981 accatacagc tcaacctgaa tctcgccacg ttccccacgc tcttctttga tggctttcag
    32041 tgcggctgcc atggttggaa tagtggcaca gcaaatacaa gtcatccagt ccgcaccacg
    32101 cttagcatta ttcttagcaa cagtaccgcc agcgtctgca cacttggtgt ctgctacgat
    32161 gatcttctct ggaaataagc tacgcagcac ctcaaccaat tcgctgccta cttgaagcag
    32221 gcaaactgtc cctgcttcga ttacatcaac ctcgtgacca actgcaacag cagccctgac
    32281 cgccccctgc aaatcagaat gatctaaggc aacctgtaat tttggaatat gtgtcatgat
    32341 tttctaccaa gagcccgtag caccgccttc aatgcttaat agcgagctcc tatcctttct
    32401 gttgtgtttg attcgtttag tgatgatggc ttgtctaaga atccaaatcc aagccctcta
    32461 aataaggact atttttggac tcgtccacca aagccaaaac ctctgctgga gtgtgacagg
    32521 caactaagcg cgaaatagcg tcttccagtt caaaaagggc gacaatctgt ggaatagcaa
    32581 ctgttgtatg aatagaagga tcagttgccg ccaaggttag caataccgaa gcctctttgc
    32641 catctgaaaa ggtcaccggc ttggtcagtg tgataagagc aaaggcattt cgcttgaccc
    32701 ctacaccagc ctctgcgtgt ggcatggcca ttcccggcat aaggacataa tagggcccgt
    32761 acttttctgt tgatgcgata atagcgtcat aatattcaga ggtcaccgcc ccgctgtcaa
    32821 tcaaaggctg aacagctagc ttaaccgctt cctgccagct agctgctgac aagcccaagc
    32881 gaatagagtt gttttcgata aatgcttttt ttaaattcat ataactatcc tttctaaatc
    32941 aaattctttg gccagacact ttttgcctca ctcctatcta gctgataaag agaaagagct
    33001 ggaatctctc ttcacaactc tcactccatc tatccttact gaaagttgat tgctacagct
    33061 tagcttacag ccaagtggct gctcttaggc tcactatcat ttgccatgag cagcactgat
    33121 gtcatcaggg ccgctctaaa gcaccgcctg tagcttggtt ttgatttcat tgtcgtccat
    33181 aagattatct agtccaacca aatgaccctt tgtacgccca tctaattcat gaatcaggtg
    33241 attagaagca accacaatat catagcctga ggcaagtccc tttgcctcac ccactgagca
    33301 agaagcagac tgaatatcag tcaccccaag ctgacgaagt gcgttttcaa ccttcatttt
    33361 aataaccatt gatgacccca tgccattacc gcatgctgta agaaccttaa ccatttattt
    33421 tcctccgaat atatgataat ttgatatgaa tgaagacctg cagaagtata tcgacaaact
    33481 cctaccagcc tgtgctaaaa gacgaataag cagctattat caccttgctt attgtgcttc
    33541 accgcggtag taagcctctt tatccttagc cctagcaaat tgtagctgtg gaatagcaag
    33601 taagaagaca cacaccacca catagcctgc aataccaagg aacttgaaga gataaccaaa
    33661 tggaagccaa ggaagcacca ggtcaatatt gccatgataa ccacctgtca agcccaacag
    33721 accaactgcc actgcaccta aggcaacctg aagaatacct gatataaagg atagagcaac
    33781 agctgccttc cagccaccac gcttatctgc ataaacagca atcgcagcat tatcaaagaa
    33841 gaccggaaca aatcctgtga tgatcaagat tggattttta aagatcacaa gaagtgcaat
    33901 agtgattagc tgaccgataa gcccaaaggt aaatcctgac aaaacagcgt ttgaagagcc
    33961 aaagccatat gacgctgcaa cgtccaccgc aggaaatgaa cccggaagga gcttacttga
    34021 aatcccttgg aaggcattgg tcaactctga cacaaacata cgcacaccct gcatcaggat
    34081 aaagagataa actgagaaag ttaaggaggt ttgcaaaata tacataaaga aggcctgctt
    34141 agctggatta aaggcaccag cacctataag ttctgcatta gacatcatat ctgggccaag
    34201 cacagccaag atagcaccaa agaaaaccag cattagagtg gcagaagcaa ccaccgtatc
    34261 atgaaaaatc gttaaaaagc ttgctagctt aagattgtca aggttctctt cttttttacc
    34321 aaagaaaggc gccaccttgt caacaaacca gatcgcaaac tgctgctggt gcccaatggc
    34381 aaagcctcca ccacctgtca agcgctgagt cgcctcaact gtcatattgg agctgacagc
    34441 ccagtaaagg ccacagataa taccgaccgc ccaagcacca aaagcatttt gaagctgagg
    34501 gattaaaaga agaacaaaca cagagatggt tgccgcctgc tgcaccatga tatgacccgt
    34561 aataaagagc gtacgaacct ttgtcacctt acgaagcgcc actagcaaaa tattgacccc
    34621 aaaaccgatc aaaagggctg tggtggcaac gctgatggat cccatctcct ctagcttggt
    34681 attggctgct gcaagtccaa agtaagggtc aataactgcg gcctttaatt caaatttctt
    34741 acccaatgcc actaggattg ggcgaaaggt gttaaccaag cccccagcac caacattcaa
    34801 aatcagataa ccaaccgttg ccttaacaaa gccagcaaat acttcatgca ggggcttttt
    34861 aagcagcaaa tacccaatca aaaccaaaag acctacaaag aaagccggat tttgcaaaat
    34921 atcttgcgaa aaccagttta ggggagctat aagcattttc ataagaacta cctcttttca
    34981 cagttaataa atatgatatt ttctatacaa taattgtaaa cgatgtaagc gtttaaaaaa
    35041 aagaccaaca atcacacaaa gaagtgttca aaaatgtact gaagccaatt tccagctagc
    35101 tctgatcact gttaaagcac tatcattaat ctctaattaa taaccaaaca catcacaaca
    35161 atatcgggct aacacaaaaa taggccagcc catactgccc agccaaaacg aaacaagcaa
    35221 tcaattcaag gcacttaacc ctgttttata tcgtacaaag cccttttaag atgattttgt
    35281 ttgtttccta atcgtaaatt agttatctga tccgttctct cctcagatat actcaccctt
    35341 atctaattct actgtcaaat agctacttac tcataagcaa atgaatatta agcaaccacc
    35401 aagctacaat aaaagacctt accctgttgg caagatctta ttcattatac aatttttcct
    35461 tctgcgacat ggactacctc atcacacaag tcttcaatat ctgtcttcag atgtgagctt
    35521 aaaatcacaa gcccattttt gctaacatct aaaagcaatt ttttcgtttg ctccacgctc
    35581 ctgtcatcta atgcattcat tggctcatct aatataagga tcttagggtg atgcatcaag
    35641 gcctgaatta accctaattt tttcttagtg cctagcgatt aatgcttaaa tgctgtttga
    35701 ctaaactgat gtaaatgata aacatctaac caaaaagcta aatcaatatc tctagcctta
    35761 ggagagattg acctaagcaa ctctagattt tgtaacaatg ttaaatgtgc aataaactct
    35821 ggattctcaa tcaaaatccc agcatcctcg atataattat ggtactgtct aattttttta
    35881 ttgtcctgat aaacagctcc ttcatctaat ttgatataac cagctaaggc cttaagtatc
    35941 aaggtttttc ccgaaccatt aatacctacc aaaccataga tattaccttc tttaaaagta
    36001 agattaatat catctagaac aaggttaccc ttatacagtt ttctaccatg ttcaatccgt
    36061 aacatctcag ctctccttat aataattgtc ataaagcata tgtaccaata ctattagcag
    36121 caggcaccac caaacatcaa acaaaaagta acgtatcaag gtgagactag caaacaagat
    36181 catagctact acagcagatg aggcatagcg tatcataaca taaatcaagc aaatatctat
    36241 agtaagccaa gataccataa gataacatag tcgttcaata tgatatggtg caccataata
    36301 ggtcatcaat acacctaata ttaaaacgat aaaaagtaac cactctttaa tatagaaaat
    36361 cgtactcgtc cgccatagct tgttaaaaaa taccaactga cttcgagcat gaaaacgaaa
    36421 gatttcctta gttccttcag ccaaatccgc caaaaatgaa atcgtaaaat aaaagctgtt
    36481 gaaggacaag cctagcaagg tgataacctt gacaaaatca gctgtctccc cttcaatcac
    36541 tggaaacggc attagcaacc gatagcacac taaattatga aaatctcgct ccccagtcat
    36601 attagcctta atcaataaaa gatgtattag taagccagta agacatgctt tcattccaac
    36661 aaccagcagg ttagataatt tcatggtgct tcctcaattt taaaacgatg cacacaccca
    36721 ctaagcctaa ataaggtgat aaaaggtaag gaatatcagc atcactataa gatgttgaca
    36781 tcaaagaagt cataagaaca tatttgggag gtaaatagct atataacaac ggtgacaaag
    36841 cccacatcaa aatcaaatag agcatgcttg acttaataaa ggattgaaga tagtcaacaa
    36901 gaaaacaaac gaaatacgta tgaacgaaca aagctaacga ttttactaag caatagtaag
    36961 ctataaaggt tgttgctcct tgaccaaaaa aacgcaatat tgagttttga tcaaaataag
    37021 gcattaaatt accgttcata tgggcaacac catttagcca agacactaaa gtcaaagcaa
    37081 atattacaat gtaaaaactc agtaaaacat ataagctcaa ctgaagcttt aaaaaaatac
    37141 accttttacc atagtcagac tttctgccaa tgaggtattt aagatgtctt gacttaaggt
    37201 aatagtaggc ataggccact aaaatcatca ctagtggata gataaaagat tgataaaaac
    37261 taaaatcaaa caccacacta tccaaacgta tcatactcaa caatagactt ttctttacct
    37321 caattccacc agataaatct actgcacttg tatcaaaaaa taagatatgc ttcaaactgt
    37381 caaaataaat aaaacctaaa aatagtaacg ggactaatgg ataaaaatag cgaaatggaa
    37441 ataatctata ctgtagcatt tatgaataac tcccctacaa aaaatcaagg aaacgcctcg
    37501 ttactaactc aattcacaat tgtagatatt taccaattgt ctggagacca actaccacta
    37561 atggttgttg ctccgtccca ccaattttca cgtaccagat gcaaggcata aaggtaccca
    37621 cttttagtat cctgtgtata aattcctctg tcgcctgtcc aagttttatc tatatcactt
    37681 cttctttgac cgttactatt agctagatag tgccttacca caatttctct attacgtcct
    37741 cttgaatcta aattaacgac ataataaggc gccgcactct tcacaagata atctttcgtc
    37801 cttccaaaag atgacgtgat tctaaaattt tgcaagtaac caatttgtcg ttctgctata
    37861 acta
//
LOCUS       DARYXS010000008        37040 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.008, whole genome shotgun sequence.
ACCESSION   DARYXS010000008 DARYXS010000000
VERSION     DARYXS010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37040
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.008"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(150..389)
                     /locus_tag="TV193_000325"
     CDS             complement(150..389)
                     /locus_tag="TV193_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEL1512563.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(548..1036)
                     /locus_tag="TV193_000326"
     CDS             complement(548..1036)
                     /locus_tag="TV193_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1512564.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREANSSGSYGGGFNSSPATNSYSAPAQQTPNFGRDGSPFGGSNPMDISDDDL
                     PF"
     gene            complement(1055..1345)
                     /locus_tag="TV193_000327"
     CDS             complement(1055..1345)
                     /locus_tag="TV193_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEL1512565.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            2721..3869
                     /gene="mutY"
                     /locus_tag="TV193_000328"
     CDS             2721..3869
                     /gene="mutY"
                     /locus_tag="TV193_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEL1512566.1"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEINYDIGDPKNRKIFQAVMEVLIDPERPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSKGRLLLEKNTQGRLLGGFWAFP
                     LIETKLVSQQLTLFEDSPIVLETMSQTTLFEERYGLMPIWSQATFPQVKHTFSHQKWT
                     IELCEGFTDSMPLAPDRELVWVAIEDMAAYPMATPQKKMLEAYLKKQS"
     gene            4640..5821
                     /locus_tag="TV193_000329"
     CDS             4640..5821
                     /locus_tag="TV193_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1512567.1"
                     /translation="MNKKSARRRRKNLITKLAMTSALTLGVGAATTLAGQTEVRADNI
                     LRLDMTDKEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQ
                     KVKELNDKVNSETQGKQELQNQLEKEKEELETLKKELEAEKAKGTGETEKLQKEIEAK
                     NAMISDLQKQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKA
                     QIEKLKHCQDTPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKP
                     GPKPEPKPEPKPGPKPEPKPEPKPGPKPGPKPEPKPGPKPGPKPEPKPEPKPEPKPEP
                     KPEAKKPEQPKPMTKPGAKKPEQSLPSTGDIRNPFFTPAAIAIMIAAGTIAIPKRKEE
                     D"
     gene            complement(6067..6381)
                     /gene="trxA"
                     /locus_tag="TV193_000330"
     CDS             complement(6067..6381)
                     /gene="trxA"
                     /locus_tag="TV193_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEL1512568.1"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            6561..7880
                     /locus_tag="TV193_000331"
     CDS             6561..7880
                     /locus_tag="TV193_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEL1512569.1"
                     /translation="MEAYELIVIGFGKAGKTLAAKMAQLGKRVALIEQSPTMYGGTCI
                     NIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGVTLYNGKASFVS
                     NKTIQVEAGQERILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTGILALTEQPQRL
                     AIIGAGNIGLEVASLYASLGSEVTMYEAAPAILGRYEPVVAELAQDYLEKAGVTFKLS
                     ATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTDIKLDDRYAVVV
                     DDYCQTTVEGLYAVGDVNGGPQFTYTSLDDFRIVFEQLTGTSQYNHKDRGYLPTTVFI
                     EPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVIVNTETNEILGA
                     TLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            complement(8220..10556)
                     /locus_tag="TV193_000332"
     CDS             complement(8220..10556)
                     /locus_tag="TV193_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEL1512570.1"
                     /translation="MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLAVKKLLQVSAEV
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILNQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IETAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATD
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKKAKK
                     WRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            complement(10629..11174)
                     /locus_tag="TV193_000333"
     CDS             complement(10629..11174)
                     /locus_tag="TV193_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEL1512571.1"
                     /translation="MLSVLILLLLSWSFYIGYNRGLILQTFYCFGALVSLLFAHHGYK
                     ALAGKLALWVPYSNPAEGAATLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAGV
                     LVHLAPVDYFDGFEAKLASGLLAVMVSVLFLSMALTVLATIPMPFIQGRLHGSLLSRL
                     LVEHCPFISSILRQLWVTAIL"
     gene            complement(11174..11485)
                     /locus_tag="TV193_000334"
     CDS             complement(11174..11485)
                     /locus_tag="TV193_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512572.1"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            11603..12511
                     /locus_tag="TV193_000335"
     CDS             11603..12511
                     /locus_tag="TV193_000335"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEL1512573.1"
                     /translation="MDTLVFKINSQVSSSLIKQLAPYRISNANPYVRLAAKKDGVTLM
                     LYTSGKLVLQGRQAAKLAQELDLQETPADQRPAPSSAQDIPLIGSDEVGNGSYFGGIA
                     VVASFVQPEEHALLRQLGVDDSKNLNDKSIAQIAPVLKKHIQHRALLLSPKKYNEMVG
                     KGKPYNAVSVKVALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFRNPL
                     TFEEKAEGKYLAVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQILAAY
                     GMAGLEHCAKLHFANTKKAQALLKKQ"
     gene            12536..13135
                     /gene="lepB"
                     /locus_tag="TV193_000336"
     CDS             12536..13135
                     /gene="lepB"
                     /locus_tag="TV193_000336"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1512574.1"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            13364..15763
                     /locus_tag="TV193_000337"
     CDS             13364..15763
                     /locus_tag="TV193_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEL1512575.1"
                     /translation="MEHFFTGTVDRIIFDNASNFFKILLLAIEDTDSDFDEADIVITG
                     TMAEIIEGEAYTFWGELTQHPRYGQQLRLSRYQKAKPTSAGLVSYFSSEHFKGIGQKT
                     AEKIIALYGNNPIDEILKNPSRLNEISSLSKANREAFVAKLKANYGTEQVIAALADLG
                     LANRFAFQLFDKYKEEAVHIVKDNPYQLIEDIQGFGFKLADSLAEQLGIESASPKRFR
                     AALLHCLLEQSIKRGDTYIQARELLALTISLLEDTRPVECDPAIVANQLTQLIDEGKV
                     MTIGTRVFDSSLYYAEDGIQKHLTRLLQQPLTKEPSQDTIDQEIQAIQEELAITYDKI
                     QKQAISQALTSKVFILTGGPGTGKTTVIRGILQAYASLYQIDLKQKDIPIILAAPTGR
                     AARRMNELTGLASATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLT
                     AINSNTQLIIVGDSDQLPSVGPGQVLADLLKVDRIPHITLDKIFRQSEESTIVDLANH
                     IRQGILAPDFCQKKADRSYFEAQAPFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGL
                     AGINSLNQLMQNLLNPLANQTEFLFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDEIIMDFDGTEIVYPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQ
                     SGRLLQRNLIYTAITRSKSKLIMLGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHT
                     AAASVKESNQSSLSVMPATSPQKEQEQPPYLLTPHNFLAIDPMIGLTEDDMLTFFKKK
                     S"
     gene            15859..16344
                     /locus_tag="TV193_000338"
     CDS             15859..16344
                     /locus_tag="TV193_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512576.1"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGSTVSYV
                     PYIIGIVLYLISIVSQLFSQIEPVSMIIVLAELALYGFAFYKAKTLNEKDKDNPQSIE
                     E"
     gene            complement(16487..17590)
                     /gene="dinB"
                     /locus_tag="TV193_000339"
     CDS             complement(16487..17590)
                     /gene="dinB"
                     /locus_tag="TV193_000339"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEL1512577.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKN
                     PRESGGRGVVSTCNYEARRFGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FKRYTDQVEPVSIDEAYLDVTTNKLGIKSALKIARLIQHDIWNSLQLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRMRKSISSERTYAKLLYQEADIKAEL
                     SKHARRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARIIDQVARELFD
                     SLEEHQAGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            17799..20123
                     /gene="pflB"
                     /locus_tag="TV193_000340"
     CDS             17799..20123
                     /gene="pflB"
                     /locus_tag="TV193_000340"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEL1512578.1"
                     /translation="MATVKTNADVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDE
                     SFLAGVTERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKDKELIFGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEI
                     NLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSI
                     QYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEA
                     VQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYPRW
                     GEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHRG
                     VYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNSLASLDFSYAADGISLTTQVSP
                     RALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLNDVYDKIMAGEDVIVRISGYCV
                     NTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            20430..20708
                     /locus_tag="TV193_000341"
     CDS             20430..20708
                     /locus_tag="TV193_000341"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512579.1"
                     /translation="MKRLKTLCLLATAITLTLAPISTSQTTTQTVYASETHQNLCTNT
                     GNGWFKCPDGHGGWTWHFDENHKSNQQSFLGGLLGFALSLWGAIIRLF"
     gene            complement(20872..21813)
                     /locus_tag="TV193_000342"
     CDS             complement(20872..21813)
                     /locus_tag="TV193_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEL1512580.1"
                     /translation="MTLEVIEKVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSGALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKDDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGNHAGSAGLFSTIRDL
                     ERFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQQAA
                     IFLTNRTYDKDDRALWIKERRQLRDAIHRTFDRNSPR"
     gene            complement(21810..22565)
                     /locus_tag="TV193_000343"
     CDS             complement(21810..22565)
                     /locus_tag="TV193_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEL1512581.1"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRVVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPVTLEFNREAGQDLTIVPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVLSDPSQIEIWFVK"
     gene            complement(23058..23906)
                     /locus_tag="TV193_000344"
     CDS             complement(23058..23906)
                     /locus_tag="TV193_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEL1512582.1"
                     /translation="MEITWTVKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQ
                     LVVVAVYKPYFVQTDNPNNILGSFSTISAVDDGDKSSRKAAYINGFLNEFVGSFVLFF
                     GAMALTKNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSL
                     GGPTGPALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVAAVAAF
                     KFLYIK"
     gene            complement(24008..24460)
                     /locus_tag="TV193_000345"
     CDS             complement(24008..24460)
                     /locus_tag="TV193_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1512583.1"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLRYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            complement(24480..25679)
                     /locus_tag="TV193_000346"
     CDS             complement(24480..25679)
                     /locus_tag="TV193_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1512584.1"
                     /translation="MEDKLFNKHFIGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYF
                     VRLFNGFGYGVVSTATNTIVTAYIPASKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIILCSVLIAVVVLGAFAFPVTDIALNSEQLAKTKSWTVDSFIERKALFITL
                     IAFLMGIAYASVLGFQKLYTTDIHLTTVGAYFFVVYALIITITRPAMGRLMDVKGEQW
                     VLYPSYLFLALGLFLLGSVTSSLPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFHQLFWLAGLIPAACAVMYFLKTQ
                     AKAIDKG"
     gene            25848..26507
                     /locus_tag="TV193_000347"
     CDS             25848..26507
                     /locus_tag="TV193_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1512585.1"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQINDQHIIITNLEKLKDNIV
                     F"
     gene            26528..28813
                     /locus_tag="TV193_000348"
     CDS             26528..28813
                     /locus_tag="TV193_000348"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEL1512586.1"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKENFAIFLRKL
                     FFHFQDTDYPLSHMIASKDLDLLTFLTSDATLTKEVFDLVALQVLGFIPAVDFTDAQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADRIKCEVVYTHGLQDWNVKPRQVYNIFNALPDSLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGDDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILAAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSDLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(28919..29311)
                     /locus_tag="TV193_000349"
     CDS             complement(28919..29311)
                     /locus_tag="TV193_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEL1512587.1"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTCSNIQANGKIEVAYVNREQLRGYRFVGRAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(29465..29722)
                     /locus_tag="TV193_000350"
     CDS             complement(29465..29722)
                     /locus_tag="TV193_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1512588.1"
                     /translation="MSKATLKELRIAQKKTQKELSALTGISVRTLARYEKDVQKLRRA
                     KYEKLRGIAEALTISVDDIFFGRRFGFYEIKSACLLIAFLL"
     gene            29901..30275
                     /locus_tag="TV193_000351"
                     /pseudo
     CDS             29901..30275
                     /locus_tag="TV193_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678526.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(30533..31315)
                     /locus_tag="TV193_000352"
                     /pseudo
     CDS             complement(30533..31315)
                     /locus_tag="TV193_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(31832..33340)
                     /locus_tag="TV193_000353"
     CDS             complement(31832..33340)
                     /locus_tag="TV193_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1512589.1"
                     /translation="MLEEYLEPVINHQALLLTILLGKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPCYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRGEFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSALLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKLLANRIELMINSWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVMQQVSPCVAKVYRFNILSEAELPWRTDFDLIVTTAEMT
                     AFIEERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILNG"
     gene            33591..34487
                     /locus_tag="TV193_000354"
     CDS             33591..34487
                     /locus_tag="TV193_000354"
                     /inference="COORDINATES: protein motif:HMM:NF012162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1512590.1"
                     /translation="MKTKSFRKVLTTSATCIVLATSFAGGTLRVWAEQLYYGWNDGTR
                     QSSPYFLYVSPKNAPKRELKDEYVVYCFNKKLYWPDQWESIYSNFNDIRSPYNDLPVY
                     EKKLGYDGIFKQYAPDYKKDISDIASALVAVLSNGYPTNKSQLSTSYHLNNDSSRKVT
                     QLAIWYFSDSLTKEYLKDTGGYNLNDMEKKALDFLISKGEDSKLKSEQSNYSLDIYVY
                     QSGGHDHMKDYQNLLGSTLIPKEPLKPQLGGFSGHNGNGLSGLEGGSSGSQETNEDGK
                     KGLIGFHGGLSGSEGKRDPFQD"
     gene            34535..34747
                     /locus_tag="TV193_000355"
     CDS             34535..34747
                     /locus_tag="TV193_000355"
                     /inference="COORDINATES: protein motif:HMM:NF014980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein"
                     /protein_id="HEL1512591.1"
                     /translation="MQSLEGGNSPIVEQNYGSTEGYHGQSGILEETEDTNPPGIILGG
                     SGNVETRSSSDGAWRWSSWRIRRNDT"
     gene            34674..35480
                     /locus_tag="TV193_000356"
     CDS             34674..35480
                     /locus_tag="TV193_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1512592.1"
                     /translation="MSKRDPHLMGLGGGLAGESGETTPKPGQTGGHGPIIETTEDTQK
                     GMSGQSGGTIESENTKKPEVMIGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVM
                     IGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVMIGGQGQIIDFSENTQSGMSGQ
                     SGDTTVIEDTKKSEIIIGGQGQIIDFSEDTQPGMSGQSGGTTIVEDTKKPTPKPKPAP
                     APIVNDEKPNKGTQLPQTNDMKQLTLSIIGAMSMLLVLCLSLFKRPSKKD"
     gene            complement(35852..36898)
                     /locus_tag="TV193_000357"
     CDS             complement(35852..36898)
                     /locus_tag="TV193_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1512593.1"
                     /translation="MRLRTYIVIGYLMSMLITIAGLIVGLNQMLITIEDISYILVIAL
                     IASVAGGIVNMILLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQM
                     SSELKVSFESLSESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLN
                     TISRQTNRLNQLVEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQEKRS
                     VHIEVAKEVVKISSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQ
                     GQGIKKEDLPLIFKRLYRVEASRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGS
                     CFSLLLPASPPLGD"
     gene            complement(36900..>37040)
                     /locus_tag="TV193_000358"
     CDS             complement(36900..>37040)
                     /locus_tag="TV193_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HEL1512594.1"
                     /translation="WEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKTVWGLGYKL
                     EG"
BASE COUNT        11107 a         8656 c         7400 g         9877 t
ORIGIN      
        1 cttagatgag gagtttttct ttagccctat gcttcatcaa acaccaccag ataccacact
       61 ctcaatcaga tcacaggcta aggcttgacg acgctgctca gctgacttca gaccacataa
      121 aaaacagccc ttaaggactg tttcagatat tagtcttcgt ttacgtaagg cataagtgcc
      181 ataacacgag cacgtttgat agctgttgtt actttacgtt ggtttttagc tgatgttcct
      241 gttacacgac gaggaaggat tttcccacgt tctgaaacga aacggctaag aagctcagta
      301 tctttgtaat caacatattc aattttgtta gctgcgataa agtcaacttt tttacggcgc
      361 ttgaatccgc cacgacgttg ttgagccatg tgttatctcc tttatattat tcacatgata
      421 aatttgctgc ctaataagca aaccgacgcc agaaagaggc ctcaatcttt tgtgcttgaa
      481 agcaactcct ctgtctccca agctaccagc aaatctatgc aattcatgtc agtccacttt
      541 ccattgctta gaatggaaga tcgtcatctg aaatatccat tggatttgag ccgccaaatg
      601 gacttccatc tctgccaaag ttaggtgttt gctgagcagg cgctgaatag ctattggttg
      661 ccggtgagct attaaaacca ccaccatatg agccagacga gttcgcctca cgtgtagcac
      721 gactttccag catttggaaa ttatctgcaa caacctcggt tacatacaca cgctgcccct
      781 gttggttttc gtagttacga gtctgaatac gtcccgtaat cccaatcaag gcaccctttt
      841 tagcccagtt agctaaattt tcagcttgct gacgccagat cacacagtta atgaaatccg
      901 cttcgcgctc accattttgg ctcttaaagg cgcgattaac agcaagtgta aacgtagcaa
      961 ctgccacctg acttggagtg tatcgaagct ctgcgtcctt ggtcatacga ccaactagta
     1021 ctacattatt aatcataaac tacctacttt gcaattaagc gtcaagctta acgatcatgt
     1081 gacgaagaat gtcaccgttg atttttgaca gacggtcaaa ctcattaaga gctacagcgt
     1141 cagtcgcttc aaggtttacg atatggtaaa ggccttcgcg gaaatcattg atttcgtatg
     1201 caagacgacg cttttcccaa tcttttgatt caacaatagt tgcaccattg tcagtcaaga
     1261 tagagtcaaa acgtgctacc aaagcgtttt tagcttcttc ttcaatgttt ggacgaatga
     1321 tataaagaat ttcgtattta gccattgata gtttcctcct tttggtctaa tgactcgcta
     1381 cccttgtaac gagtaagtga ggtatgctca cagattaaca gtatacaata aacaaaggta
     1441 aaaagcaagc aaaatgttga cctttctgtt gaataaaaga ccttcttaga tcccttcgta
     1501 gctccataaa aagcaaagcc acttctatag aaatgacctt tagtcacctg acttgcaggt
     1561 cttagtggca aggtcaaatc cagacaccag caaaaaggac acccaaccgg gtgtccttat
     1621 catgtcttga gtgctattct cccttctatc tgccatttaa taaggagtca cctgtcaatt
     1681 gttcctctaa agaggaacac atacttatct gtctaatcag tcgtctcctt tctgtttaac
     1741 aaaatgaacg gttattaaaa gaatatgact gttcttgagt ttcgtttgtt agcactgtgc
     1801 tattttggct tacattggac tcactccttc agctattttt tgctgtcgtg ctcaatgtct
     1861 ccgtttttat atcttgcgat gtacataaga ccctcctatt agaaaagctc actagctatc
     1921 tgatgatagc tacctttcaa ataagctcaa tcctttaccc tgagtgccaa taacaatatc
     1981 aaggacgact agtgacacag caactagtct ccatttttat agcgtccttt attgaatctt
     2041 agcatagcat acgtcctttc aataacggga atttcaagct tatactgttt agagcgctcc
     2101 tttggccaaa gctggtaatc tcgataagcc ttcacatgtg atcacatatt aaattgtaaa
     2161 attggttttg cctaccgttt gttggagctc ttaatctcca tttttgtacc gcgcgacatg
     2221 tcttgttatc atcagatatc ctcctataac tccagtgtca tcggtcgtcc ttatctacat
     2281 ctttattata atgtaagcgg ttactaaagt caagcttttt gctccttttt tgataacata
     2341 tcagcaacta aaaccccacg ataggacaca agccttcagc aaagactgag aaccttttta
     2401 tacttgtcat ttacgttcaa gtgcctttgt caatacctca gagtcattaa ccttttcgcg
     2461 gtcagctaat ctaaccaacc actctgaaac ggtaacagtt ttacgaacag ctttattatt
     2521 tttgataaat ggtgttgaat cagcttgtag gaactggtaa attcagacca caatcaatat
     2581 aagcagcaag aacattttct aacatgtcat gagcagttgt cacagcctct ttataaggta
     2641 taaatcacaa agcatgcttt aacaaatcct atcggacgca gggttcaacc aattcagaca
     2701 atctgtgtta caataggatt atgatagatt taaatgatta tggcattacc atgtgggatc
     2761 aagataccat tgcctccttt cgtcgtacgc tgctagcttg gtacgatcag gaaaagcgag
     2821 acctgccttg gcgtcgcaca aaggaccctt atcatatctg ggtctcagag atcatgctcc
     2881 agcaaacgca ggtcgttacc gttattcctt attacgagcg atttttggat tggtttccaa
     2941 cggtagaggc cctcgcctgc gctgacgaag agcgcttact caaggcttgg gagggactgg
     3001 gctactactc tcgtgtacgc aatatgcaaa aggctgcgca gcaaatcatg actgactttg
     3061 gcgggatttt cccaagctca cacgctgata ttactaagtt aaagggcatt ggcccttata
     3121 cagctggcgc tatctcaagc attgcctttg atctgcctga gcctgcggtt gatggcaatg
     3181 tcatgcgagt catggccaga ctgtttgaga ttaattacga tattggagac cctaagaacc
     3241 gcaagatttt tcaggctgtt atggaggtgc ttatcgatcc ggagcgaccc ggagatttca
     3301 atcaagcctt gatggatctg gggactgata ttgaagcggc taaaaatccc agacctgacg
     3361 agtctcctgt gcgctttttc tgtgcagcct accgacatgg tacctatgac aaatacccca
     3421 tcaaggagcc aaagaaaaag ccccggccta ttcaggtgca ggcctttgtg attcgtgaca
     3481 gcaaggggcg gcttttgctc gaaaaaaata cccaagggcg cttgctaggt ggcttttggg
     3541 cctttcctct gatagagacc aagcttgtca gtcaacaact gaccctcttt gaggacagtc
     3601 ctatcgtgct tgagaccatg tctcagacaa ccctttttga ggagcgttac gggcttatgc
     3661 ctatctggtc tcaagctacc tttcctcagg tcaagcatac ctttagccac caaaaatgga
     3721 ccattgagct ttgcgagggc ttcacagaca gcatgcccct agcccctgac agagaacttg
     3781 tctgggtcgc aatagaggat atggctgctt acccaatggc aaccccacaa aagaaaatgc
     3841 tagaagccta cctaaaaaaa caaagctaag cggctcatag ctgtcagata aggtccttaa
     3901 ggcagagctt tagggacttt tttgcttgcc caaggagctt acttgtagcc tacttggtct
     3961 gatcagacaa gaaaaactcg atttcttgta acaaagtcag acgattaccc ttttcattaa
     4021 aaaaacgaaa ctacggagac aaattgggac actgctatgt cttgtcgtca gctgtcgtgc
     4081 tacactggcc ttagaaacta agcacagcca aaagctgtga aaactataac tatattatgg
     4141 aggagaaaac acaatgaagc tgacaaatgc cctatgccta gtagccgcta ctgcagccct
     4201 agccctagca ccaatcaaca caagcactgg acaaactaat accgttttgg caagtcaaaa
     4261 aagtacagga cattgtactc atactagaag tggatggttt aaatgccctg atggaggatc
     4321 atattacgac gaaagttacg atacacattc atcatggtta atttggcttt atggtgcttt
     4381 ttactctgca tgggaaatta taactagttg gttcaaataa attagtaaag caggtcaggt
     4441 tattatcggc ctgcttttct taatcagcct tgctaatgcc tgctgaattg ccagaaatca
     4501 gacaattagc cttttcatta aaaccaaaaa ccgaacgaat ctaggagaga aagtagcgga
     4561 caactatttc tctatcttga tgactgtgtt aaaatatctt cagtcaaaat taatatgtct
     4621 atcattaaag gagagagaaa tgaacaaaaa atcagcaaga cgcaggcgta agaatcttat
     4681 tacgaagctt gcgatgacaa gtgccttaac cctgggtgta ggcgcagcga ctaccctagc
     4741 aggacaaaca gaagtacggg ctgataatat cttacgctta gatatgacag ataaagaagc
     4801 agttgaaaaa ttcgctaacg agcttaaaaa tgaagtccat aaaaactatc gtggtagtaa
     4861 tacttggcaa aagcttaccc ttatacttaa tggttatcaa aaccttagag aacaaataga
     4921 gaccgagcta aaaaatagtg aacaaaaagt aaaagagctt aatgataagg ttaatagtga
     4981 aactcaagga aaacaagagt tacagaatca gcttgagaaa gaaaaagaag agttagaaac
     5041 actaaaaaaa gagcttgaag ctgagaaggc taaaggaact ggagaaacag agaagcttca
     5101 aaaggaaatt gaagcaaaaa atgcaatgat ttctgaccta caaaaacagc ttgaggaaac
     5161 taagcaaagg gttcaagagt ttgaagctga agtaggtaaa ttaatggccg aaaaggcaga
     5221 cctacaaaca aaattaaatg aacaagagca gcttaacgct aagcttcaaa aagaaattga
     5281 agacttaaag gctcagattg aaaagcttaa gcactgtcaa gatacaccta agccagagcc
     5341 taagccagag cctaagccag agcctaagcc agagcctaag ccagagccta agccagagcc
     5401 taagccagag cctaagccag agcctaaacc agagcctaag ccagagccta agccagagcc
     5461 taagccaggg cctaagccag agcctaagcc agagcctaag ccagggccta agccagagcc
     5521 taagccagag cctaagccag ggcctaagcc agggcctaag ccagagccta agccagggcc
     5581 taagccaggg cctaagccag agcctaagcc agagcctaag ccagagccta agccagagcc
     5641 taagcctgaa gctaagaagc ctgaacaacc taaaccaatg actaaaccag gagctaagaa
     5701 gcctgagcaa tcacttccat caactggtga catcagaaat ccattcttca cgcctgcagc
     5761 tattgctatt atgatcgcag caggtaccat tgccattcca aaacgcaagg aagaagatta
     5821 aacaaattaa caatccccat atttcaacaa tgatacacaa gcccctactt gtgtccacct
     5881 caaaagcagt agccagtcgc gcggctactg cttttactat gcttttttta caccagctct
     5941 gatagcagct aataacaaaa aagattgaag acacagctta ttgggtcccc gatctttttt
     6001 tggtcataca accaacagca gctcttgagg cttgctgtcc ttctaagagg ctgttggctt
     6061 gttgctttag cttaattctg ctacgatagc cttgatttga tccttggtat ggacgcctgc
     6121 tacttgcttg acaaccttac cgtccttttt gaacagcagg gttgggatag acataatgcc
     6181 aaattgttga gcagtattgg ggttgtcatc aacatctagc ttgacaatct taagctcagc
     6241 ttcgtcaatt tctgctgcta attgatcaag gattggcgct tgcattaagc aagggccgca
     6301 ccaggttgcc caaaagtcca caaggactag gccttcatta gtttctgctt caaatgttgc
     6361 atctgttacg atatgtgcca ttgtaatctc cgttcttata gtttataagc ctattttagg
     6421 ggaaaacgac tgataatgca agaatctgat acgaagacct cggtcttatg atttaagaaa
     6481 aatctggcgt agccatttta agacaaatac gctggccttt gctacaatga ccttatctta
     6541 acaactaaaa ggaggctact atggaagcat acgagcttat tgtgattgga tttggtaagg
     6601 ccggaaaaac tttggctgcc aaaatggcgc agctaggaaa aagagttgcc cttattgagc
     6661 agagccccac tatgtatggc gggacttgta tcaatatcgg ctgtattcca acaaaggcct
     6721 taatcactgc tgctgagcat aatgctagct ttgcagacgc tatggcgcac aaagatactg
     6781 ttgttcatcg tcttcgccaa aaaaatgagc agctgctagc tcagtctggt gtgacacttt
     6841 acaacggtaa ggcaagcttt gtctctaata agacgattca agtagaagca gggcaggagc
     6901 ggatcctctt agagggcaag catatcgtga tcaataccgg agctgtttca aatcgctttc
     6961 cgatacctgg tctagcagat agtcagcatg tggttgatag tacagggatt ctagctctca
     7021 ctgagcagcc tcagcgcttg gctattatcg gtgcggggaa tatcgggcta gaggttgcca
     7081 gcctttatgc cagcttaggc agcgaggtta ctatgtatga ggctgcacct gctattttag
     7141 ggcgctatga gccggttgtc gctgagctgg cacaggatta cctggaaaaa gctggggtta
     7201 cctttaagct ctctgcgact gttgagctga ttgctaatga tgaagcaggt agagttctag
     7261 tgactgctaa tggcaagaca gaagcctttg attgtctcct ctatgctatg ggacgtaagc
     7321 ctgccactca aggccttggc ttggaaaaca ctgacattaa gcttgatgat cgctatgctg
     7381 tcgtggtaga tgattattgt caaaccactg tcgaggggct atatgcggtt ggtgatgtta
     7441 atggcgggcc tcaatttacc tatacgtcct tagatgattt caggattgtg tttgagcagc
     7501 taacaggcac aagccagtac aaccacaaag atcggggcta tctgccaaca acagtcttta
     7561 tcgagccgcc actttcacaa attggtctaa cagaaaaaga agcaaaagag cagggactgc
     7621 cctacaaggc taatgagctc ttggttgcca atatgccacg cgcccatgtc aataacgacc
     7681 tcagggggat ttttaaggtc attgtcaata cagagactaa tgaaattcta ggggcaacct
     7741 tatttgctaa caattctcac gaatacatta acctgattaa gatggctatg gataaccaga
     7801 ttccatatac ctatctcaaa aaccagctct ttacccaccc gtcaatggct gaaaatctta
     7861 atgatgtctt taacctttaa aagaacctca acctcacctg catagcaggt acaacagcca
     7921 aactattaaa aaaacaaact cctttttggc tgcttatcac atggataggc ggctagcaaa
     7981 aggagcttgt tttttcttgt atccaatcag caggctagca gctgctcatg gtctaaagga
     8041 actagctagg ctgggacacg ttggtagcaa aagtccagca agactcacta gctgctgtca
     8101 tgagctttga agagcagcac ttagggaaca cgcccagtag ctttctttgg gacgcttggc
     8161 tcacctaggg ctcaatcagc ttgagtaaaa aggggcttta tttgaatcaa gaggatcaat
     8221 tagcctagat tagctatggt acagcctgag ccgccagcat tttgcggggc atagccaaag
     8281 cttttgacat gcttgttgcg tcgcaagtac ttgccgaccg cttcacgtat aacacctgta
     8341 ccaataccat gtatgatgtc aacctgactc atgttgttaa gcaaggcttg gtcgataaag
     8401 gcatctagct cctgcatggc ctcctcatag cgcttgcctc gaaggtctaa gcgagcgcgc
     8461 ggcccttttc ctgtagctgc ttttttgacg accttgacag ctctcttctt aggctgctgc
     8521 gcttcttctt ttagcttaac caagctgaat tcgtcttcct tgagggtcaa cttgatcagg
     8581 ccaacctgag cctcccacct cttgtcctta agctgggcaa gcaaggttcc tctttgccca
     8641 taggcggtaa caatgatgtc atcacccaca cgaggagccc gccatttttt cgcttttttc
     8701 agcaccttat tttgcgacag gctttgctct ggcgcaagct gctttaggcg atgcttggct
     8761 tcgataattt cgtgcggctt tagctctgcc ttttcatgca gctgacttaa aatgctatca
     8821 ctttctgcca aggctatatc cacaatctca cgcgcttcaa gggctgcctt ttccaattcc
     8881 ttgtccttag cgtgggagaa ctcgttatag agctttttaa cagcacgatt gaatttgagg
     8941 ttatcctgct cgacctcctt gatatgctca aggcgcttgc ggctttctaa cgtttgctgc
     9001 tctagttgct caatgatacg attgacatca tgatcagttg cggtcatcgc ctgagcttcc
     9061 ttgacgatgt gctctgctaa gcccaatcgt ctcgcaatgt caaaagcatt tgagcgacca
     9121 ggcactcctt gcatgaagcg gtaagtaggc tttaggctga cattgtcaaa ggccatgctg
     9181 gcattttcaa cataggctgt ctcaatccca taggccttta gctctgggta atgggtagtg
     9241 gccatcgtct taatattggt cagacgcagc tgctccaaaa tagccatagc aaggctggct
     9301 ccttcctgtg gatcagtccc tgctcctagc tcgtcaaaga ggatcaagct gtcactgtct
     9361 gcctgattga gaatctcaac aatgtgagtc atatgactgg aaaaggtaga caggctttgc
     9421 tcaatggatt gctcatctcc aatatcagca taaataccat taaaaactgc caccctggag
     9481 cccttgtcag ccaaaatagg cagccctgac tgggccatca cctgagcaag ccccaaggtt
     9541 ttgagcatga tggtcttacc acctgtatta ggaccggtga tcacaattac tgctaagtca
     9601 tttgcaaaat gcagatcatt tgccacaggg ttttgaatca aggggtggcg cgcattgagc
     9661 agctgtaagc ttttatcgtc agaaatcact ggcacagttg cctgtttggc ttgcatataa
     9721 aggtattttg ctctcacaag atctaaatgt cctagtagcc aagcgttatt cctaagagat
     9781 cgactatgcg gacgcagctg ctctgacagc tcatgcaaga ttcgtccaat ctcatggcgt
     9841 tcatctgtct gtagctgagt cagctcctca ttgagactta caagcgctct aggctcaatg
     9901 tagaccgtac tgccagaagc tgacatgtca tgcacaacgc ctgccacctt atgacgatag
     9961 gtgtttttga caggcaggac acttcggcca ttacgactag caatcaggct ctctgacaaa
    10021 taagctgcct gtttttttag gatatcctgc aggagctgac gactggcatg ctccttgttt
    10081 gatatctgac gacgaatgct ctccaattca ggactagcaa agccttcaac aaagcctgcg
    10141 tcattaatgg cttggagact cccctgtaag ctaggaaagc tctctatttt ttcaaagagt
    10201 gcttttagag cgactaaatc aacattttcc aaatcagcgt aaaaacgaca gacctctgcc
    10261 gacacctgca ggagcttttt aactgctaaa agctcttgaa tgctcagatc tgcctctaaa
    10321 tccaaacgct gcatgctttc tgagacatct gatagccctc ccaaggcaaa atggtggtgc
    10381 tctacaaaaa tagccgccat ttcctcaagc tctgtaaagt aagcctgtat tttgtcttta
    10441 ttcgcaatag gctccaacaa gtcaagctct agctgcccct gctctgtctg taaataaggc
    10501 caaaattgct ctttaacctt ttcaaattct aactgttcta aaatcttttt ttccatagtt
    10561 cttattatac ctaaaaatca cttaaaatgt gggacactaa acaaaaagag accagagaga
    10621 ctctgacctc aaagaatagc tgttacccat aattgcctga gaatgcttga gataaaggga
    10681 caatgctcaa ccaagaggcg agacaaaaga ctgccatgta ggcgcccttg aataaagggc
    10741 atgggaatgg tagcaagaac ggtcaatgcc atgcttaaaa acaaaaccga aaccatcacc
    10801 gccagcaagc cactggctag cttagcctca aagccatcaa aataatccac cggcgcaagg
    10861 tgcaccaaga cacccgccaa tcgaaccaca gcatagccta ctgtagacag tataaaaaat
    10921 gctatccctg cataataaac cttatccaat tcaaaaatat taatatcctt aaaaaataag
    10981 gtagctgctc cctcagcagg attagaataa ggcacccata gagccagctt gcctgccaga
    11041 gccttatagc catgatgggc aaacaagagc gacaccaagg ccccaaaaca ataaaaggtc
    11101 tgaaggataa gccctctatt gtagccaatg taaaagctcc aagaaagcag taacaatata
    11161 agcactgaga gcatcatgac acctcatctg tatctgcttg actagccttt tcctgaatac
    11221 ctgccagtgc cttctcacgc agctcgacaa tctcagcttc gattttttca atctcaatct
    11281 ctctactcag ttgggctgac agggtattga tggtcatcaa aatagcaacg gtttcgtcgt
    11341 ctgcttctgg cagacgctcc ttgatggcct gatatttttc ctttgccaca cgatcaacct
    11401 cttccataaa gaggttgtct ttgtccgttg tcaatgttaa tgtcttctca ccaaatgtta
    11461 atttgtaacg attaatattc ttcataggct caccccttta gcattatacc ctaaaaatga
    11521 cttttcgtaa aattgtgaaa ttaatctgag attgcatgga atgatttccc ataacaggac
    11581 attttatgtt aaaataatgt tcatggacac cttagttttc aaaatcaatt cccaagtcag
    11641 cagcagcctg atcaagcagc tagcaccata ccgcataagc aatgccaatc cttacgttag
    11701 actggctgcc aaaaaagatg gtgtcacact gatgctgtat acctcaggca agctggtgct
    11761 gcaaggcaga caggctgcaa agctggctca agagcttgat ctgcaagaaa cgcctgctga
    11821 tcagagaccc gcaccctcca gcgcacagga tatcccctta attggtagtg atgaggtggg
    11881 aaatggctct tactttggag gcattgctgt tgttgctagc tttgtgcagc cagaggagca
    11941 cgccttgctc agacagctcg gtgtcgatga ttctaaaaac ctcaatgata agagtatcgc
    12001 ccagatcgct cctgtcctaa aaaagcatat tcaacacagg gcgcttttgc tatcgcctaa
    12061 aaaatacaat gaaatggtag gtaaggggaa gccctacaac gctgtttctg tcaaggttgc
    12121 tcttcataat caagcgattt ttctgctctt aaacgacgga gcaagaccag aaaaaattgt
    12181 cattgatgcc ttcacaagtc aggccaatta tgacaaatac ctacagcaag aaaaaaatca
    12241 ctttcgtaat cccttgacct ttgaggagaa ggccgaaggc aaatatctgg cagttgctgt
    12301 cagctctatc attgctagac agctattttt agacaatctt gacaagctca gtcaagatct
    12361 gggctaccgg ttgcctagtg gtgctgggcg tccatctgat cagattgcca gtcaaatctt
    12421 agccgcctat ggtatggcag gcttagagca ttgcgctaag ctgcactttg caaacaccaa
    12481 aaaagcccaa gcgctactaa aaaaacaata atcttagaaa aataaaggaa aagtcatgaa
    12541 acaatttatt aaagaatggg gagcttttac cctttttatc ctactttttg gactctcacg
    12601 tttgttccta tggcagcctg tcaaggttga tggccactca atggacccaa ccctagcaca
    12661 tggcgagagg ctcattatct tcaacaaggc taagattgat cgctttgata ttgttgttgc
    12721 cagtgaggag gacgagaacg gacagagaaa agagattgtt aagcgtgttg ttggcatgcc
    12781 aggtgataag ctgtcttata gaaatgacac tctttatatc aacaacaaga aaacaaaaga
    12841 gccttatctt gatacctacc tgacgagttt taaaaaggac aaattacaat caacctatgc
    12901 ttacagtgat ctcttccaag agctggctga aaatgctgct gcctttaccg tcaactccga
    12961 aggaaaaaca gaatttgaca tcactgttcc aaagggcgaa tatttcctac tgggtgatga
    13021 ccgcattgta tctcgtgaca gccgcgaggt cggctccttt aaaaagcagg acatcgttgg
    13081 tgaggttaag ttccgctttt ggccactcaa taaaatcaat ctcttcccta gatagcaggc
    13141 aagctaaagc tattttctag cagggctgat ataggctcta tgcccacagc agtaaagact
    13201 cagggcagca atagcctcta tctatatctg cttatctatc cataccaaga ggcttgatgt
    13261 gctatccaag cactcagcta gctttagaga agcagctatt gttgacgttc taaaacctgc
    13321 cgttgtgcag gttttcgact atcttgcaca gaaaggtacc gtcatggaac acttttttac
    13381 aggcactgtt gaccgaatta tctttgacaa tgcgtcaaat tttttcaaaa ttctattact
    13441 ggctatagag gatactgata gtgattttga tgaagctgac attgtcatta caggcactat
    13501 ggctgagatc atagagggcg aagcctatac cttttggggt gagctgaccc agcacccaag
    13561 gtatggtcag cagctgcgcc tgagccgcta tcaaaaggct aagcccacct cagcaggtct
    13621 cgttagctat ttttccagtg agcatttcaa gggcattggg caaaaaacag ctgagaaaat
    13681 cattgccctt tacggtaata atcctattga tgagatttta aaaaatccca gtcggcttaa
    13741 tgagatctct agcctttcta aggctaatcg tgaagccttt gtggcaaagc ttaaagccaa
    13801 ttatggcact gagcaggtga ttgctgcctt ggctgatcta ggactggcca atcgctttgc
    13861 ctttcagcta tttgacaaat acaaggaaga ggctgttcat atcgtcaagg acaatcctta
    13921 tcaactcatt gaggacattc aaggctttgg ctttaagctg gctgatagct tagctgaaca
    13981 gctaggaatt gagagtgcct ctcccaagcg ctttcgtgcg gctctgctgc attgcctgtt
    14041 ggagcaatcc atcaagcgag gcgacaccta tatccaggca cgtgagcttt tggcgctgac
    14101 cattagccta ttagaggaca caaggccagt cgaatgcgac ccagctattg tcgctaatca
    14161 gctaacccag ctcatcgacg agggcaaggt tatgactatt ggcacgcgtg tttttgacag
    14221 cagcctttat tatgccgaag acggcattca aaagcatctg acacgcttac tacagcagcc
    14281 tctgactaag gagcctagtc aagataccat tgaccaagaa atccaagcca tacaagagga
    14341 gcttgctata acctatgaca agatccaaaa gcaggccatc agccaggcac tgaccagcaa
    14401 ggttttcatt ctaacaggag gcccaggcac aggaaagaca accgttatca ggggcatttt
    14461 acaggcctat gccagcctgt accagattga cctgaaacaa aaggatattc ccattatcct
    14521 agcagctcca actggtcgag ccgctcgtcg tatgaacgaa ttaaccggtc tagcaagcgc
    14581 aactattcac cgccatcttg ggttaaacgg agacaatgat taccaagcaa tggaggatta
    14641 tttagactgt gatttgctga ttgttgatga attttccatg gttgatacct ggctggccaa
    14701 tcagctatta acagccatca attctaatac ccagctgatc atcgtaggag atagcgacca
    14761 gctgccttct gtcggtcctg gacaggtact agctgacttg ctaaaggttg atcggatccc
    14821 tcacattacc cttgacaaga tttttcgcca atcagaggag tcaaccattg ttgatttagc
    14881 caaccacata cgccaaggca ttcttgctcc tgatttttgt cagaaaaagg ctgatcgctc
    14941 ctactttgaa gcgcaagcgc cattcattcc cggcatgatg acaaagatcg tacaggctgc
    15001 cctaaaaagt ggcatcccag ctgaggaaat tcaaatccta gcccctatgt acaaaggact
    15061 agcaggcatc aacagcctca accagctcat gcaaaacctc ctgaatcctc tagctaatca
    15121 gacagaattt ctctttaacg agacggcctt tcgtaaggga gacaaggtac ttcaccttgt
    15181 caatgacgct cagcttaatg tcttcaatgg tgatattggc tatatcacag acctcattcc
    15241 agccaaatat accgaatcca agcaggacga aatcatcatg gactttgatg gcaccgagat
    15301 cgtctaccca agaaatgaat ggttaaaaat cacccttgcc tatgccatga gcattcacaa
    15361 atctcaaggc agtgaatttc aggtggtaat cctgcctgtc acccgtcaga gtggtcgact
    15421 tctgcaaaga aacctcatct acactgccat caccagatca aaaagcaagc tcatcatgct
    15481 cggagaaata gccgcctttg aagaggcaat caaaaaagaa ggtgacaagc gacacaccta
    15541 tctcgtacaa aggcttcaag tggctgaagc tgatgaccat acagcagctg cttcagtaaa
    15601 ggaatcaaat cagtctagcc tatctgtaat gccagctacc agcccacaaa aggaacaaga
    15661 gcagcctcct tatctgctca cccctcataa tttcctagct atagacccca tgattggtct
    15721 aaccgaagat gatatgttaa ccttttttaa gaaaaaatca taatatatta aaaaagtaag
    15781 gcacaatcct tattcctatg ctataatatc catgtatcat cttaaaagta caataacata
    15841 acattcaagg agacttatat gatttcatac gaacaagtac gacaagcact cagaacatca
    15901 actattacga tcattatcat caatgctatc agcatggtta tcaccttgtt tggacttgct
    15961 ggcattttct ttttgaagtc tcaattggat aaacctgaat ttcgtgcaca attttcagct
    16021 gagcagctaa ggctatttga ggttggcata tcacccttta ctatttttat gtcagtgatt
    16081 agccttggat tggttgtttt gaccactgtg ctttgtggct ttaacctctc aaaaatcaaa
    16141 caaggttcca ctgtcagcta tgttccttac attataggga ttgtgctcta tcttattagt
    16201 atcgtaagcc aactatttag ccaaattgag cctgtctcaa tgatcattgt cctagctgag
    16261 cttgcgcttt acggctttgc cttttacaag gctaaaaccc ttaatgaaaa agacaaggac
    16321 aatccccaaa gcattgaaga ataagcaggc cataaaggta tgataacaag acttcctgtc
    16381 tgccttcaaa tatggctctt tgtcagccca ctacggttga caaagagcct tttttaacca
    16441 ctaaaaaagc aagaggaaaa ttgataatgt cctcttgctt tttttgttag ttgaatgaca
    16501 ggtccaacaa aatatctgtc actttatcct ttagtccggt cattgtgact cccaataagc
    16561 ggattcctgc ctgatgctcc tccaggctat caaaaagctc tctagccacc tgatcaatga
    16621 tcctagcatc tcttgttaac tcaggtaggc taacccgctt ggtcaaggtc gtaaagtcag
    16681 cataccgaac cttcaaaaca atgatccttc ctagtttttt attcgcctca agcaaatcag
    16741 cgacccgtct tgcatgttta gaaagctctg ccttaatatc agcctcctgg tagaggagct
    16801 tagcataggt acgctcactg ctgatggatt tgcgcatacg attaggcttg actggagaat
    16861 gactaatgcc tctggccttt cgataaagct catagccaaa gcgtccaaac tgatcaatca
    16921 gggtcatctc aggaacacgc aaaagatcct gcccagtgta aatccccatc tcatgcagcc
    16981 tttcaactgt tcgcttacca acgccatgaa acttttcaat cggaagcttt tctaagaatg
    17041 gcagagcatc atcaggaagt actagggtca gaccatgtgg cttttcaaaa tcactagcta
    17101 gcttggctaa aaatttgtta taagaaacac cagcagagca ggtcaactgc aggctattcc
    17161 aaatatcatg ctgaatcagt cttgcaatct ttaaggcaga cttgatgccc agcttattgg
    17221 ttgtcacatc taaataagcc tcatcaatag acacaggctc cacctgatcc gtataacgct
    17281 tgaaaatctc tctgatatca tagccaatcc tacggtactt agcatgatct ccagagataa
    17341 aaatagcctg aggacaacgc tcgtaggcct cctttgagct cattgcagag tgaatgccaa
    17401 accttcttgc ctcgtagtta caggttgata caacgccccg tccaccactt tctctagggt
    17461 tcttgccgat caccaccggc ttgcccttta attcgggatt atctctttct tccaccgcag
    17521 caaaaaaagc atccatgtca atgtgtataa tcttgcgtga ggtgtcatta atcagcggaa
    17581 aaataagcat aggtccctcc ctcctacatt atactccttt aggcttttaa agccaaggca
    17641 gaggattgta tgacagtttt caactgtttc agcaaactgt aatataaaag aatcttgtat
    17701 ttgtcaagat ttttgcttgg gaaatcgttt cccctatggt aaacttagat tgtaaatgta
    17761 acagattgga cttgttacta gattttaagg agaaacttat ggcaactgtt aaaactaacg
    17821 cagatgtttt tgaaaaagct tgggaaggct ttaagggaac tgactggaag gaaaaagcga
    17881 gtatatctcg ttttgtacag gctaactata caccttatga cggtgatgaa tcattcctag
    17941 caggtgttac tgagcgttca ttgcacatca aaaaggtcat tgaggagact aaagctcact
    18001 acgaagcaac acgcttccca tacgatactc gtccaacctc aattgctgac attcctgccg
    18061 gatttattga caaggataag gaattaatct ttggtatcca aaacgatgag ctattcaaat
    18121 tgaacttcat gccaaagggt ggtatccgta tggcggaaac aactctgaag gaaaacggct
    18181 atgagccaga tcctgctgta catgagattt tcactaagca tgtgacaacg gttaatgacg
    18241 gtattttccg cgcttacacg tcaaacattc gtcgtgcgcg ccatgcccac actgtaactg
    18301 gtctgccaga tgcttactca cgtggtcgta tcatcggtgt ttacgcacgt cttgccctct
    18361 acggagcaga ttacttgatg caagaaaagg tcaacgactg gaatgccatc actgagatcg
    18421 acgaagaatc aatccgtctt cgcgaagaaa tcaacctgca ataccaagca cttggcgaag
    18481 tggttaagtt aggtgatctt tacggtgttg acgttcgtcg tcctgctgaa aacgtcaaag
    18541 aagctatcca atgggttaac attgccttta tggctgtttg ccgcgtgatc aatggtgctg
    18601 ctacttctct tggacgtgtc ccaatcgttc ttgacatctt tgctgagcgt gaccttgcac
    18661 gtggaacctt caccgaatca gaaattcaag aattcgttga tgattttgtc ctcaagcttc
    18721 gtaccgttaa gtttgctcgt acaaaggctt atgacgctct ttattcaggt gacccaacct
    18781 tcatcacaac ctctatggct ggtatgggta atgacggtcg tcaccgcgtt acaaagatgg
    18841 actaccgctt cttaaacaca cttgacaata ttggtaactc tccagagcca aacctaaccg
    18901 ttctttggac tgataagtta ccatatgctt tccgtcgcta ctgtatgcac atgagtcaca
    18961 agcactcttc aatccaatat gagggtgtga caacaatggc taaggacggc tacggtgaaa
    19021 tgtcatgtat ctcatgctgt gtgtcaccac ttgacccaga aaatgaagag caacgtcata
    19081 acattcagta cttcggtgct cgtgtgaacg tgcttaaagc ccttcttact ggacttaacg
    19141 gtggttacga tgatgtgcac aaggactaca aggtatttga catcgaccct gttactgatg
    19201 atgtccttga ctttgatact gttaaggcta actttgaaaa atcacttgat tggttgactg
    19261 atacttacgt agatgcgctt aatatcattc actacatgac tgacaagtac aactacgaag
    19321 ctgttcaaat ggcattctta ccatcacatc aacgtgctaa catgggattt ggtatctgtg
    19381 gcttcgcaaa tactgttgac accctatcag ctattaaata tgcgactgtt aagccaattc
    19441 gtgacgaaga tggttacatc tatgactacg aaacaatcgg cgactaccca cgctggggtg
    19501 aggacgatcc tcgctcaaac gaattagctg agtggttgat tgaggcttac actacacgtc
    19561 tacgcagcca caagctttat aagaacgctg aagcaactgt gtcactgctt accatcactt
    19621 caaacgttgc ttactctaag caaactggta actctccggt tcaccgcggt gtttacctca
    19681 acgaagatgg tacaactaac ctatcacaac ttgaattctt ctcaccaggt gctaacccat
    19741 ctaacaaggc taagggtggc tggctgcaaa acttgaactc acttgcaagc cttgacttct
    19801 catatgccgc agatggtatc tcactaacaa ctcaagtatc acctcgcgcg cttggtaaga
    19861 cacatgacga acaggttgaa aaccttgtta ctatccttga tggttacttt gaaaatggtg
    19921 gtcaacacgt taacctaaac gttatggact taaatgacgt ttacgataaa attatggctg
    19981 gtgaagacgt tatcgtccgt atctctggat actgtgtcaa taccaaatac cttacaccag
    20041 aacaaaaaac tgaattaact caacgtgtct tccacgaagt gctttcaatg gacgatgccg
    20101 ctgaagctat ttcaggaaaa taagctaatc ttagctagct aagagcctgt ctgttgacag
    20161 gttctttttt tatcacacat gcaataggta cagctgtcct cagcagctga ataaccagca
    20221 gagctggttg aaactactag caagcctatc attatcattg tgaaaatcag acgattaacc
    20281 ttttcattaa aaaaaaaaaa aacgaaacta cggagaaaag ctgatgagga gctctttaag
    20341 gctatcagtc aacatgttaa actcttctta ggaagcgtta acaataacta actgctaagc
    20401 taagcaatta tctattaagg agaataacaa tgaaacgact aaaaacacta tgcttgttag
    20461 ctactgctat aaccctaacc ctagctccta tcagcacaag ccagacaaca acacagaccg
    20521 tatatgctag tgaaactcat caaaatcttt gtacgaacac tggtaacgga tggtttaaat
    20581 gtcccgatgg acatggaggg tggacttggc attttgacga aaatcataag tcaaatcagc
    20641 agtccttttt gggaggattg ttgggctttg ctttgtctct atggggagct attattagac
    20701 tcttttaagc tctagcttaa ctaatcctca aacaacaaaa ataagctctt agagaactaa
    20761 gctctaaggg ctttttgctg ttctgataag taaaaaccaa gagacaagga catcaaaaac
    20821 aagcaggcct atcagatata ccacctgata ggcccacttg tgctctcatt cttatctagg
    20881 actatttctg tcaaaggtcc tatgaatagc atcccgaagc tgtcgtctct ctttgatcca
    20941 caaggcccta tcatccttgt cataggttct attggtgaga aaaatcgctg cctgctgctc
    21001 ctttttattg agcatgataa aaggccctgt atagcctgta tgactaatcc aatcaccctc
    21061 taggctccaa cccaaagacc tgggcttttc ctgtctgcta tagctttgaa aaagtctatc
    21121 cgaaaagctt tccttcaggt aatgctcaat aaaccgctct aaatccctga tggttgaaaa
    21181 aagccctgct gagcctgcat ggtttcccaa gaccttagcc ttgggatcat gtacctctcc
    21241 atcaagcacc cctttgaccg ttggaactgc ttctggcctt gggccaaagg aggtctcagt
    21301 cattccaaag ggagtaaaaa ccatctcctg aaaaagctca tcaagagact ttccatgaag
    21361 gtgctctagc atgaagccaa gcaataaaaa attcacatct gtgtaatgaa aggtcttatc
    21421 gtccttgacc tgaagctggt gcatcgctgc tcttaattgc tgggcattga gctgatctcg
    21481 attgggaata taagggtcaa gtccactagt atgggtgagt agctgtcgca gtgtaacctc
    21541 cagcttttga gcgtcaggat aataatgcct taaaggagta tcaagagcca aggcaccact
    21601 attgatcatg gctatacaga cagtcgctac tccgacaacc ttagagacac tggctaaatc
    21661 ataaaccaag cctttggtaa caggtctttg accatcaagg gtaccgatat aatgctcctg
    21721 ccaaccgcca cagcgaaaaa gggctaagct agccccatga tataagcctt cctgaatctg
    21781 ctggcttacc ttttctatga cttctaatgt catttgacaa accaaatttc gatctgactt
    21841 gggtctgaaa gaacaagcac ccttgccttt ttatctaaat aaacctgaca ccctttgtcc
    21901 tcaaggtagg tctttagagc aagcaagtca tagctatctg acacctgaaa ttctaaaatc
    21961 tccaaatccc atgtgacatg cgggacaatc gtcaaatctt gaccagcctc cctattaaac
    22021 tcaagcgtga ccggcaggca atcaccaaaa atagactgat aaaaagctct ggattgctcg
    22081 tcatctaaaa catttaagac aatcagatca aagctaaact gactcagccc cctaaagtca
    22141 gcttccttgt caattgcagg aacatcatcg acaatgtcaa gctccttgat atcgtcctct
    22201 gcatggagta agaagcgatc tccctctggt gaggtgactt caaaggcata gccttttttt
    22261 cccttgaaaa tcaaatcata gtcaacgcca tgagctagga gctgctcaat gtccttagga
    22321 gcagttgttt tgataacaat tgtatttact ttcttagggc catctacaac gcgtgttctt
    22381 gctgctggag attcttcaat tacaaagcgt tcttgtcctt ggccccaaga tgaaaaaatt
    22441 gatatcgcgt tttcctctga cactagcctt aagcctagat ttttttggta aaaggcaata
    22501 ttaaggtcgc gattgttaac acgtaatact ggggttttaa agacaatatt gtcaaataaa
    22561 gtcatatatt cctcctaatc ctctgctatt atagacaaaa ttccaatttt tgacaagaaa
    22621 ttatatgctt tttaaccgcc tgtcacgcgc taccaaggca atatagcact cacagccatc
    22681 accagactta ctaggtccaa tcttccttcg tgcgctctat cacaagcagc tttccttagc
    22741 gtaactcatg cacatattgg taaatgcgac tttttcaaaa tagcacatga agtacccctt
    22801 taatttgact tttccttaac caaaagcgag aacctttttt agttctcaca gtagcaatca
    22861 cactcttgaa atgtgatttc gctctcctca ataacagatg ataactgaaa ttgcccggat
    22921 tttcttatcc acgcgcaact tcaaaagcac cttatcttca gcattagtaa ggatactacc
    22981 agcttagctc agaccagatt cagctggctc ttgctggcaa gcttttatca caaaaaagaa
    23041 ggcctaagcc ttctttttta cttgatataa aggaatttga atgctgctac tgctgctact
    23101 gctgctagca ctggggcagc aaccggtacc catgagtacc accattttga atcccccttg
    23161 gcttgtccaa ggactgattt tggtaagaaa tggtgaacca aacgagggcc taagtcacgc
    23221 gctgggttga gcgctggacc agtaggacca ccaagagagg tcacaagagt catcaccaag
    23281 aaaccaatcc ccaagtgagc tactgcaagt gagcctgtca cgtaaggaga gatttgcgtt
    23341 gcagctgttg tttggtcata gccagcctct accagcttac caacaagctc cacaccaaag
    23401 taattcttgg ttaaggccat tgcgccaaaa aagaggacaa aggaaccaac aaactcgttc
    23461 aaaaagccat taatgtaggc tgccttacgg ctgctcttgt caccatcatc aactgctgaa
    23521 atcgttgaga aggatcccaa aatattgtta gggttgtctg tctgcacaaa ataaggcttg
    23581 tacaccgcaa caaccactaa ttggccaaac atagccccta gcaattgagc aagaacatat
    23641 tgtaaaacgt gtgcccaagg gaacaagcct gaaactgcca agccaaaggt aaaagctggg
    23701 ttaatgtgat ttccagaaac gttaccaaac ataagtgccg gcatcatcac accgaggcca
    23761 tagccaaagg caatcacaag ccagcctgag cggttaccct ttgttccctt taagtcaaca
    23821 ttggcaactg ctccatttcc caaaataatc aaaaatgcag tggcaataaa ctctgtgatg
    23881 tatttcacag tccatgttat ttccatattc tctagtttcc tccaaatgat aagtataaca
    23941 gataccattt tatcagggat actagttctt gtaaagccta ttgtaagata ttgcctgctt
    24001 aatatgttta cagtgttttt tcacaattac ggacaactaa taagtctttt ttagcatgtc
    24061 gcaggatata ctctgaggtc gatccaatca gcagacgctc aaaggtattt aagccagttg
    24121 ctcctaccat gatcaaatca gcctgctcct tttcaggtat gtcactagct aagagctttt
    24181 tagggttgcc tctttcgatg atttttttaa tgctgctaac gcctctgcct ctagccattt
    24241 tctcgtaata gcgcaacacc tccttggcat gctcctcttg tgtgtcaaag acataatcac
    24301 taaccattgc atcaccctga taggccttaa catcaataac atgagccagc agtaagaccg
    24361 catcattgcg aagggcaaca ttaatggcct tctcaacagc taattctgat tcgtaagagc
    24421 cgtccaccgc agccagaatc cgtttatatt tgcttatcat ctttgtctcc tttcgttgat
    24481 tagcctttat caatagcctt tgcttgtgtc tttaggaaat acatgactgc gcaggcagct
    24541 ggaatgagcc ctgccagcca gaacaattga tgaaaggact gcacaccaga cccaagaagc
    24601 atatccttga tgagtcccaa cagataaggt cccgcaccca agcccaaatc tagcccaatc
    24661 atataagtag acatagcggt attaaagcga tgctcctcaa cccccttgat ggaggctgcc
    24721 tgtccgcagg acataaaggt tccatagcca aagcctatca aagcacccga aagcagatag
    24781 ggaaggctgc ttgtcacact accaagcagg aaaagcccta gcgccaaaaa gagatagctg
    24841 ggataaagaa cccactgctc ccccttaacg tccatcaagc gtcccatagc aggtcgtgtg
    24901 atcgtaatga tcaaggcata taccacaaag aaataggctc ccaccgtcgt caaatgaatg
    24961 tctgttgtgt ataatttttg aaagcctagc acagaagcat aggcaatccc catcaaaaag
    25021 gcaatcaagg tgataaataa ggcctttcgc tcaataaagc tatcaactgt ccaggatttt
    25081 gtttttgcca gctgctctga gttgagggca atatctgtca caggaaaggc aaaggcccct
    25141 agcacaacta ctgcgatcaa cacactgcac aaaataataa tcatccgaaa atcaatgtgc
    25201 aaattatcca gcataaaggt cccaacaaaa ggaccaatcg ccgccgctag gcttgttgat
    25261 agaccataaa aattaatccc ctctccgcgc ttgctagctg gaatataggc agtcacaatg
    25321 gtattggttg ctgttgagac aacaccatag ccaaagccat taaacaagcg cacaaaatac
    25381 atcatgccaa tcgttggcat gaaaaagtag gctagcgttg ttaggagata aaaaatggcg
    25441 cctcctctta gcactaagcg tcggccaaaa acctccaatt gcttgccaaa aatcagtcga
    25501 gccagcaggg ttcctaggat ataaatcccc gtcgccagac ctgcctcact ggtcttagct
    25561 cctaattcct tagtcgcaac aaaggcaatg atcaccgtaa acaagtaata gaccatatac
    25621 acaataaaat ttaatactgt gatccctata aaatgcttgt taaataattt gtcttccact
    25681 gaaaatgagc tcctccctat ttcattaaca ttttacaaaa aaatcagata atgccccatt
    25741 tcaatggtat aatataggtg atactattaa acgacattag caaatgctaa gcattgctgc
    25801 agcaacaaat tatataatga taccagaaac acctctagga gaaaagcgtg aaccatcaaa
    25861 tcttacagcg ttatattgac agtcataact ttcctattat cgaaaagggc taccacaaat
    25921 acctgacctt tgaaagctta gaggaggatt ttacgtatat cctaaaggag ggcattgtca
    25981 agcaaagcgt tctgtcaaaa tatggcatgg aatttaacct caggtacgtc acaggccttg
    26041 agatcacctc tgtgcttaat actggctatt ccaaggacat gagagagccc tacaatgttc
    26101 gcatcgaatc tgagactgcc agcttttata aggttcgtca ttccaccttt ttaagggata
    26161 ttagcgagga tatcgagctg cagggctatg tcaaggactt ttatcactac cgcctccaaa
    26221 aatcaatgaa aaaaatgcag tgtatgctga caaatggccg tatcggcgct atctctactc
    26281 agatttacga tttaatgacc ctttttggac gccccttggc taatggccat atccttattg
    26341 attttatcat cacaaatgag gagctgggca aattctgtgg catttcgact gccagcagtg
    26401 tcagtcgtct cctaaagcag ctcaaaaaag agggcattat tcaaatcaat gaccagcata
    26461 tcatcattac caatttagag aagctaaagg ataatattgt tttttaacga tttagaaagg
    26521 acgtcccatg cgctataatc aattgtctta cattcccacc agtctagaaa cagctgtagc
    26581 tgagcttcag gccctgggct ttgctgtcca gcaagagcaa gcacccaagg agaacttcgc
    26641 tattttcctt agaaagctat tttttcattt tcaggatacc gattatccct tgagccatat
    26701 gattgcaagc aaggatctcg acctattgac ctttttaaca tctgatgcaa cactgacaaa
    26761 agaggttttt gatttagtgg ccttacaggt ccttggcttt attcctgctg ttgactttac
    26821 cgatgcacag gactttatac aaaagattgg ctttccgatt gtttttgaca gccagcaatt
    26881 actactcaat ttacatcagc tgcttgcaac ccggcagaag tccggtgtga ccttgattga
    26941 tagccttgtt agtcagggct tgcttcctat ggataattgc taccactact tcaacggaaa
    27001 agccctagca acctttgata ccaccagcct cattcgcgag gtggtctatg tcgaagcgcc
    27061 acttgatacc gatcaagacg gacagcttga cctcatcaag gtcaacatta tccgccccaa
    27121 ggccagcact gctatcccaa gcatgatgac agccagccct tatcaccaag ggattaacga
    27181 gaccgccaac gataaaaagc tccatcgcat ggaaggtgag cttagcccta aggctcctcg
    27241 taggattacc gttgagccaa ctgattttca gccgcttgcc accaagccct caaggcttcc
    27301 tgtcaatgag tgccaagaga ccttcagcca tatcagctcc tacacactaa atgattattt
    27361 tctagcgcgt ggctttgcca atctctatgt ctcaggagtg ggaacagcag gctcaactgg
    27421 ctttatgaca agtggtgact acgcccagat cgaaagcttt aaggctgtta tcgattggct
    27481 aaatggcaga gctactgctt acacgagcca caagcgtgac tatcaaatca aggctgattg
    27541 gtcaaatggc ttagtcgcaa caactggaaa atcctatctt ggtaccatgt caacaggact
    27601 ggctacaaca ggtgttgatg gcttagcagt catcattgct gaagctgcca tttcttcttg
    27661 gtacgattat tatcgtgaaa atgggctggt atgcagtcct ggtggctacc caggagagga
    27721 tctcgatgtg ctgacagagc tcacctactc gcgtaacctg ctgccaggtg attacttacg
    27781 tcacaacgac cattatcaac agctgctgag ccaacaatct caagctctcg agcgccaatc
    27841 aggcaactac aatcaatttt ggcatgaccg caactacctg ccacaggctg atcgcatcaa
    27901 gtgtgaggtc gtctacacgc atggcctaca ggactggaat gtgaagccta gacaggtcta
    27961 caatatcttc aatgccctgc ctgatagcct tggaaagcac cttttcctac atcatggtga
    28021 gcatgtctac atgcacaact ggcagtcaat tgattttcgt gaggccatga atgccctgct
    28081 ctgtcaaaaa atgctaggac aaaataatgg ctttacccta ccaacaatca tctggcagga
    28141 taaccaaaaa gaacaaacct ggaaagagct aacagccttt ggcggtcaca gcaagcgtca
    28201 gattgcccta ggcgatgatc atgtcttaat tgacaatcac tatggcgaag aggactttaa
    28261 gcgctatagc aaggattttc gtgcctttaa agctgagctt tttgaaggca aggcaaatca
    28321 agcagtcatt gatattctgt tagaagagga tctaccaatc aacgggcaag cctgccttaa
    28381 gcttaagcta aaatcaagtg aaaacaaggg gattttggct gcacagctcc tagattatgg
    28441 caagaaaaaa cgctttgctg atatacctgc tattcttgag ctagacagca ttgacaacgg
    28501 gcagcagttt gcacgtgaag cgctcaagga gcttcccttc aaggacagcc cataccgcgt
    28561 tgtcaccaag ggtgtcctaa acctacagca ccgcagcgac ctattgacca ttgaggatat
    28621 tccaaatgac caatggatga ccatcacctt ccacttgcag ccaaccatct atcatatggc
    28681 caagggagac accctaagag tcgttcttta cacgactgat tttgagcata caatccgcga
    28741 caatagcaac tatgccctaa ccctagattt ggagcaatcc tatctcctaa tccctactga
    28801 tgaggaggaa taaatcaaag cgcatcaaaa aagcctgaga tcacaatgag ctgcacccca
    28861 atcgttagat cctttgtcta actgttggag tacagctcaa agctctaggc ttttttaact
    28921 attttgaaac ctttttacca gcctcagcac cagaatgcag gctgtagacg gactcgatat
    28981 gaatcaagcc tgctgccttt ggtgcgccca tcttgccttc tgcccattcc ttggcagcct
    29041 caaagacagg accctctgta atgatttccg cacgccctac aaagcgataa ccacgcaatt
    29101 gctcgcgatt gacataagcg acctcaattt taccattagc ctgaatatta gagcaggttt
    29161 ggccgccagt attttcatta taaaccaagg tttcatcgtc taacagtctc atcgaacgct
    29221 tagggccaat attaggatta ccctcattat ctacagttac taccattgct aattgctcag
    29281 caatcatttc tttcatttct tctgttaaca tataatctcc tcttaatcgt ttctatagtc
    29341 agctgactac gctttgatta tagcacagtt aagcagaaaa gccgacaaaa ataggttagc
    29401 ttaaaaaagt tttacagttt acttaagatt agaatgattc tcgctatcta gccatcaccc
    29461 ttgatcacag taaaaaggcg attagcaagc aagcactctt tatttcataa aatccgaatc
    29521 gtcgcccaaa aaaaatatca tcaactgata tggtcaatgc ctctgcaata cctcttaatt
    29581 tttcatactt agctcgccta agcttttgca catccttttc atatctggct agtgtcctaa
    29641 cagaaatccc agttaacgct gacagttcct tttgggtctt tttttgagca atcctcaatt
    29701 cctttaacgt tgcttttgac aatattttcc ctccgcctct catctcaggt aatattaatg
    29761 acagatgaca agtttattat agacttcggt ttttatgaag tcaagtcttt tatcgcactt
    29821 tccccacttc tttttctaaa tcttttgatt tagcttgatt tgtggtatca tatcctatat
    29881 agaaataaag gagaatggaa atgtccgaaa agaaaacatt ttttgcaact aatttaaaat
    29941 atcttcggct aaaaaagaat atggaacaat tagaacttgc taacctttta ggacgaaaaa
    30001 gctcttcctc aatcagcgaa tgagaaagag gaaagtacac tccaaaatct ggtctcctga
    30061 gtgacattgc tgccatcttt gatgtcagcc tgacagacct catggaaaag gatttaacac
    30121 tggaaaataa gggagtgact tatcagcttc cccaaagaga tttagtaatg atttcagagc
    30181 agctatctga aaacaattat aacaaatggc tggattttgg tcaggatctc ttatctcatc
    30241 aggataaaga agaaaatcac aagccaagca aataaagagc ctcacacgtc ttattctcat
    30301 caagtttcga aaaatcacct accactcaag cacacaaaaa gccttggcag ggcttctaag
    30361 cataagaaag ctgtatcata tcaatacctc agggaccatg atatgataca gctttttgta
    30421 tctcactttt agacaaggta gccacataaa gcttgcagat gacctacctc tgtattagct
    30481 accacaacca acagctagct agactggcag gccctctata agcctcagcg gattatctaa
    30541 gcactcccaa cagctccaac aaaataaaga cataaccaat accattattt aagatatggg
    30601 ctactgttga aaaatagata ttcttcttcc aaacataaac taagccgagc aaaagtccca
    30661 gtccaccata cacaacgatg gaagatagct cgctgaagga atagatatga accaagccaa
    30721 atagcaatga tgatcccaac aatcgagcca gcagcatacc tgtgcctgat tggccctcac
    30781 cgattaaaat cttgcggaaa ataagctcct cattgaaggg accaataata ctcaccacca
    30841 gaataaagat cactgtctcg aagccctcac tagcattata gcgattagct aaaacagctg
    30901 cattgctgct ctcttctaaa ggaaggctac tgagcaaaat atttgcaaca taaagcactg
    30961 caaaaatgac caagacccac aaggtatttt tgacccattt tgttgaaaac tgccgccagt
    31021 ccctctgata atctgctcga taaagccaac agatcccaag tgcaaaaatc agcagatgtc
    31081 tcccgtaaaa taaaaaggta ttcaataaag gcggaagctc aatcacattg ctaacttgtc
    31141 tataaagata cacagcaatg atatatagca tgaccagtac agctgcacga tgacgtttga
    31201 tggtatccaa ttactcttcc tcaattctaa taattgtcag attagctagg ctatattgcc
    31261 atcagctaat cttgatctta aatgtgacta atttacaagc actcaacttt tgaatcggta
    31321 aagctgacag acagccctac cctagcttca ataaagctat cttccaatag tccttgcgct
    31381 catcagaact gtcaaaggcc tgacccagct gagtcaacag acttatccag tcaacatcac
    31441 acagaacaag accatcttac catatccctg ccaactataa aagcccctaa cctgacctat
    31501 ttgactacta acagcaaaaa agcagcttaa aaacaccaat cagacgccac caaggactct
    31561 tgatcagcgc agctcgcaca gacacctgaa aaatgacaga caagcctctt aaaagcacct
    31621 cagcaagctg agccaaccct tcacagaata gacaaacaac aagagctaag tcaagacctc
    31681 aagctagcag attacaggca gagacgcttg caaggcttac ccagcaaaaa gcaacagact
    31741 gataaaggat tcacaccaca cagccacaag tcaagcagct agcccaaaca aagcactgct
    31801 caccaaatcc tactatgctt tctggtagcc cttatccatt caaaatcgta tccaaggctt
    31861 cttgatattg cttgtctcgc aattctctga tcacctgtga taaatactct gcctgataca
    31921 tcacaaagtc aaaattgaaa tccagaattt tggtgttctc attcaatgac agcctctcct
    31981 cgataaaagc agtcatctca gctgttgtca caatcaagtc aaaatcagtt ctccaaggca
    32041 attcagcctc tgacaaaata ttaaaacgat agacctttgc aacacaagga ctcacctgtt
    32101 gcatgaccaa gctatataaa atatcaatgt ttttcttgtt gatttcgatc actgctatgg
    32161 ctaaaggtgg cagaccttct ctaacaagct gttccagtcg cgtgcaaagc aaatgcaaat
    32221 tagagcctgt cagccgacca acaccagaaa cccgctctgc ccagctatta atcatcagct
    32281 cgatacgatt ggccaagagc ttactgcctt gatattcctc cgcataataa tatttttgcg
    32341 ggataaagag cgacaaatca aacaaggtct tacgaaaata aggaatcaag gtctgaatac
    32401 aagccttgtc aaaggcgata tagtggccaa acaattgacg cagctcaccc agcagctctt
    32461 ggtaagcagg atcctcctga atgatcgtca ataaggccga agaatcctcc tcagaccatt
    32521 gtgtgatcga aaaagagttg ttaaccgtca aataaacgag aaaaatataa tcaatctcgc
    32581 tactgggaaa gtccatatca agcaacaatt tcccctcacg cttgaaaaag tcctccaaat
    32641 acccataaag cgccaaagac tttaagcgtt taaaaatccc ctcctgagga atcgcaacgt
    32701 caaactctcc acgcttccaa gatagcgaca agagcacatc aaaaaagcga aacttcttat
    32761 ccagtaacgg gtgaggcgtt tgttgctttt tgatcgaaaa gataaagtca tgcacaatat
    32821 ccagatcatg gtcagtcagc tcatagatga caatcccgta cttatcatgc aataaagcaa
    32881 tcaaatagcg gatacgccac tcctcaccaa caacactatt atcctctaag gccaagccgc
    32941 actcctcaac aaagggcttc atgtgctgaa tcagccgata agctgacggt gtggaaataa
    33001 aatgctccct agcaaagcct gagacagatt tgaccttata gcaaggtgcc ttgatcaaga
    33061 gaaatttaag aatgtgcagc cgtaccgatt ggcggtaaat cgtcttcaaa aacggtttgc
    33121 cccttttcaa aacggtgcag cggacaatgg tgctatccca ctcaaaggcg atatctcctt
    33181 ggaaaagctc ctctaattgg tggatatagc gctttatgtt agctaggcta aagcccgtct
    33241 tttgctgaat ggcgtggaaa ctgatccttt ttttaccaag tagtatggtc agcagcaaag
    33301 cctgatgatt aatcactggt tccaaatact cttcaagcaa aacactttct cctccttaaa
    33361 ccatttcgtt agcgtcatta tcataacaat ttttaccaaa aaagtgatga aaaatattta
    33421 atatcaggac gatttttctg atagccttta ttataacaca aaagctcaag gcaggtaaaa
    33481 cgataaagaa atcaacttaa aactatgaca cagtctcatc tcatatgata tagttattca
    33541 ggtttcctaa tggaaaacat attaacaact taataatgga gagaagaaag ttgaaaacaa
    33601 aatcatttag aaaggtactg acaacgtcag ctacctgtat tgtgctggca acaagctttg
    33661 ccggaggaac cctaagagtc tgggcagagc agctttatta tgggtggaat gatggaacga
    33721 gacaaagttc gccatatttt ttgtacgtat cgcctaaaaa tgctccaaag cgtgaattaa
    33781 aagacgagta tgttgtttat tgctttaaca aaaaattgta ttggccagat caatgggaat
    33841 ctatatacag caattttaat gacatcagat ctccatataa cgatttacct gtatatgaga
    33901 aaaaactagg atatgatggt atatttaaac aatatgctcc agattacaaa aaagatatta
    33961 gtgatatcgc aagtgctttg gtggcagttt taagtaatgg ataccccact aacaagtcac
    34021 aactatcaac tagctaccat ttaaataatg attcttctag aaaagttact caattagcca
    34081 tttggtattt tagtgatagt ttaacaaaag aataccttaa agatacgggt ggttataact
    34141 taaacgatat ggaaaaaaaa gctttagatt ttttaatcag taaaggagag gattctaagc
    34201 ttaaatcaga gcagagtaat tactcattgg atatttatgt ttatcaaagt ggcgggcatg
    34261 accatatgaa agattaccaa aatcttctcg gctctacctt aattcctaaa gaaccgctaa
    34321 agcctcagct aggtggtttt agtggacata atggaaatgg attaagcggc cttgaaggag
    34381 gatcatcagg ttcacaagaa actaatgaag atggtaagaa aggacttata ggtttccatg
    34441 gaggactctc aggaagcgag ggcaaacgag atcctttcca ggattgaagg gtgaggctgg
    34501 tgcacctgat acacctcaaa agcctaatga cccattgcaa agtcttgaag gtggtaactc
    34561 tcctatcgta gaacaaaact atggtagtac tgagggatat catggtcaat ctggcattct
    34621 tgaggaaacc gaagacacta acccacctgg tatcatttta ggtggctcag gaaatgtcga
    34681 aacgagatcc tcatctgatg gggcttggcg gtggtctagc tggcgaatca ggagaaacga
    34741 cacctaaacc aggacagact ggtggtcatg gaccaatcat cgagacaaca gaggacacac
    34801 aaaaaggcat gtctgggcaa tctggcggca ctatcgagtc agaaaacacc aaaaagcctg
    34861 aggtcatgat tggtgggcag ggacaaacca tcgaaacaac agaggacaca caaaaaggca
    34921 tgtctgggca atctggcggt actatcgagt cagaagacac taaaaaacct gaggtcatga
    34981 ttggtgggca gggacaaacc atcgaaacaa cagaggacac acaaaaaggc atgtctgggc
    35041 aatctggcgg tactatcgag tcagaagaca ctaaaaaacc tgaggtcatg attggcggtc
    35101 agggacaaat catcgacttc tctgaaaaca cgcaatcagg tatgtctgga cagtctggag
    35161 acactacggt cattgaggat accaagaagt ctgagataat cattggtggg caaggacaaa
    35221 tcatcgactt ctctgaggat actcagccgg gtatgtctgg gcaatctgga ggcaccacaa
    35281 ttgtcgaaga caccaagaag ccgacaccta agcctaaacc tgcacctgcg ccaattgtta
    35341 atgacgaaaa acctaacaaa ggcactcagc tcccacagac aaatgatatg aagcaactca
    35401 ccctaagcat catcggtgca atgtcaatgc tgcttgtcct atgtctgtct ctattcaagc
    35461 gaccatctaa aaaagactaa gcaacactga caagtgatca ttattgtacg gacgtttaca
    35521 ggcgggcttt ctgccctctt aaaacaccgt acaacaacaa aacggtctaa atagaaatat
    35581 ccctcaaggg ttagacaatc gctctagccc ttggggcttt ttttgatact tataatagaa
    35641 gagagcaagc agtgacactt tctttttgcc ctatatctgc taacactagc ggtatgtgca
    35701 gttaccatag gctatcaact cgtcgtgcaa ctctagagaa aagctgatac aaaaaacaag
    35761 caccagcctt gctgctgatg cttgctccgg acttactgat aagcctttgt gatgtcctag
    35821 ctttataacc atatgcctat tacctaaagg tctagtctcc taatggtggg ctggctggta
    35881 aaagcaagga gaaacagctc ccctttccaa gctggctctc aacagcaata tccccaccta
    35941 gttggcgagc taactgccta gcaatagaga gccccagccc atgaccacca gtcttcatat
    36001 tgcgagaggc ctcaacacga tacaggcgct tgaaaatcaa aggcaggtcc tcttttttga
    36061 tcccttgccc ctgatcaata acatcaatgc gaatggactg ctcctgttga taagcatgaa
    36121 tcgtcaaagc cgtattagcc tttgaatatt taagcgcatt gctgactaaa ttcagcataa
    36181 tccgagacaa agcatcatat cggctgctga tcttaaccac ctcttttgcc acctcaatat
    36241 gaacggagcg tttttcctgc tctaaggtca attgaaattc ggatagcatg tcaatcaata
    36301 gcttttcaag atagatgatt tgaagctgct gcttgtcgtc ttgcttttga tcatttaagc
    36361 tgaccatatg caattcttca actaattgat tcaaacggtt ggtctgtcgt gagatggtgt
    36421 ttagatagtg cctttcctct tcccttggaa taacgccatc taaaatcccc tctacagttg
    36481 cttgaataga ggtcaagggt gtcttaatat cgtgcgacag ctgagcaatc atcatggatt
    36541 tctcatgctc actctcactc aatgactcaa agctgacctt tagctctgag gacatctgat
    36601 taaaggcttc ctctagatct ttaaactcca aaggacactt gatgagctga ccactatcaa
    36661 agtttctttc agaaatagcc tgtatctttt tctttagcct tttaagcgat gaaaaaacat
    36721 tactcaaaag gatcatattc acaattcctc cggctactga agcaattaga gctattacta
    36781 aaatatatga aatatcctca atggtaatga gcatttggtt taacccaaca atcaggcctg
    36841 caatagtaat cagcatagac attaaatagc caatgacaat gtacgttctt aatcgcatgc
    36901 tacccctcta atttataacc tagtccccaa accgttttaa tggttggtgt ttgctcggta
    36961 ctgtattttg ccaagtcatt gcgtagggaa tgaatgtgaa catttaaggt attggtatca
    37021 tctaaatact cctcctccca
//
LOCUS       DARYXS010000009        34004 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.009, whole genome shotgun sequence.
ACCESSION   DARYXS010000009 DARYXS010000000
VERSION     DARYXS010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34004
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.009"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            23..949
                     /gene="cysK"
                     /locus_tag="TV193_000359"
     CDS             23..949
                     /gene="cysK"
                     /locus_tag="TV193_000359"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEL1512595.1"
                     /translation="MSKLYHNITELVGKTPIIKLRNTSPEEAADIYVKLEAFNPGSSV
                     KDRIALAMIEAAEKAGMIKPGDTIVEPTSGNTGIGLSWVGAAKGYRVLIVMPETMSIE
                     RRQIIQAYGAELVLTPGSDGMKGAIAKAEEIARETGAWMPSQFDNPANPKVHEETTGQ
                     EIIAVFGEKGLDAFVSGVGTGGTISGVAHALKAVNPDISIYAVEADESAVLSGEESSP
                     HKIQGISAGFIPNTLDTKAYDHIIRVASEAALATARSIGAKEGFLVGISSGAAVYAAI
                     QAAKELGKGKKVLAILPDNGERYLSTALYQFD"
     gene            complement(1336..1698)
                     /locus_tag="TV193_000360"
     CDS             complement(1336..1698)
                     /locus_tag="TV193_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL1512596.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDNI
                     HQILRLGEAVLVQVIDYDEYSHKVSLSLRTLEEEKHHVSSHHRFSNSRYKIGFKPLEA
                     SLPNWIEEGLDHFKQEKS"
     gene            complement(1698..3098)
                     /locus_tag="TV193_000361"
     CDS             complement(1698..3098)
                     /locus_tag="TV193_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1512597.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKNTGYMPESIQRVFKELKK
                     KGILTGIASGRARYGVPKEVQDLQADYCVKLNGAYVKDNQKNIIFQAPIPADTVVAYK
                     KWANAVGIDYGMAGRHEAVLSARNEMISDAIDKVYSTLEVCPDYNEHHDVYQMWTFED
                     KGDDLQLPVELAEQLRLVRWHDHSSDVVLKGTSKALGVSKVVEHLGLRPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPQLQEKADFITKTVEENGILYALEELGLIDKELHFPQL
                     DLAGHEGPRVVMKTNHGELTLALFPEHAPKTVANFLGLAKEGYYNGVIFHRIIADFMI
                     QGGDPTGTGMGGQSIYGQSFEDEFSEELYNLRGALSMANAGPNTNGSQFFIVQNTSLP
                     YSQKELERGGWPKDIAAAYAEHGGTPYLDRRHTVFGQLADEASYQVLDNIAAVETGAQ
                     DKPKEDVVIEAIEVFD"
     gene            complement(3131..3772)
                     /locus_tag="TV193_000362"
     CDS             complement(3131..3772)
                     /locus_tag="TV193_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1512598.1"
                     /translation="MSNITVILVDDHEMVRMGLKSFLNLQQDVDVIGEASNGREGVEL
                     ALELRPDVVVMDLVMPELGGVEATLEILSKWKEARVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVAKGELAIETEVDKKIKAHDQQPNLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDH"
     gene            complement(3765..4769)
                     /locus_tag="TV193_000363"
     CDS             complement(3765..4769)
                     /locus_tag="TV193_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1512599.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFDYLRSHLWQLER
                     LVFSVVLLIISVTLLLLLLWIILDDNSKRSINKNLRRILNNQRIHLEETSEINTNLTR
                     LSAKMSHITTNIQKKENAYILDSQKIIQQERKRIARDLHDTVSQELFASSMILSGVSM
                     SLDQMDKEQLQQQLVTVEAMLQNAQNDLRILLLHLRPTELANRSLSEGFTMILKELTD
                     KSGIEVVYKENIGTLPKAIEDNLFRIAQEFISNTLKHAKASRLEVYLNQTPTELQLKM
                     VDNGVGFDMGQVRELSYGLKNIEDRVNDLAGTLRLISQKGKGVSMDIRLPLVMGDEDE
                     "
     gene            complement(4766..5458)
                     /locus_tag="TV193_000364"
     CDS             complement(4766..5458)
                     /locus_tag="TV193_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL1512600.1"
                     /translation="MKKFQFFLLVECMLLAMGIMTILANDLSSFILILVLILLALRFY
                     NQDTRNSFLLTVSLLLLFLIFMLNPYVIMAVLLGIVYVIINHFSQVKKKNRFALIRFA
                     EEKMTVRQVKNQWLGAANYESDYYSFEDINIIRASGNDTIDLTNVIVTGMDNVIIIRK
                     IFGNTKILVPIDVAVTLEVSSIYASVDFFELQEYDLRNESITLGEAEDSSLKKVKIIV
                     STIAGNVEVARR"
     gene            complement(5591..7486)
                     /gene="pknB"
                     /locus_tag="TV193_000365"
     CDS             complement(5591..7486)
                     /gene="pknB"
                     /locus_tag="TV193_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEL1512601.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGSDLKKYI
                     QDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSSVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIDENPNVPQALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYN
                     RSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAVDARLEQTSQMDTLQKPQ
                     KKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEA
                     GLKVGKVHQIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDY
                     QDVMTSLTETYGVPKSKIKIERIVTNEYPENTVISQSPSAGEKFNPAGKSKITLSVAV
                     GDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSSKAVVSG
                     QTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQ
                     NDAVTTP"
     gene            complement(7483..8223)
                     /locus_tag="TV193_000366"
     CDS             complement(7483..8223)
                     /locus_tag="TV193_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEL1512602.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIKDWLLTTIEAENQRIYDLGQSEDYKGMGTTVE
                     AVALVDSNAIYAHIGDSRIGLVHEGNYSLLTSDHSLVNALVKAGQITEEEAASHPQKN
                     IITQSIGQASPVEPDLGVKVLEKGDYLVINSDGLTNMIANEEIVDILCQDISLDEKNQ
                     ALIDLANQRGGLDNITVALVHKESGEAE"
     gene            complement(8261..9583)
                     /gene="rsmB"
                     /locus_tag="TV193_000367"
     CDS             complement(8261..9583)
                     /gene="rsmB"
                     /locus_tag="TV193_000367"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEL1512603.1"
                     /translation="MANDWKKSARGQALLIVEDIFDHGAYSNLALKHQLANQFLSDKD
                     KALVTEIVYGTISRKITLEWYLAHYIEDRDRLDKWVYYLLMLSLYQLAYLDKVPAHAI
                     VNDAVNLAKARAHGRGADKLVNAVLRQLTNKPLPDIKSIKRKNKYYAVAYSVPVWLVK
                     KLIDQFGEERAVAIMESLFVRSRASIRVTDLTKLDEIKQATGSEQSLLARTGLTKRAG
                     NFAASSYFINGDITIQDETSQLVAPTLDIQGQEMILDACSAPGGKTAHIASYLTSGKV
                     VALDLYEHKLALVNENAKRLGVADRIETKVLDAREVHKHFAKNSFDKILVDAPCSGIG
                     LIRRKPDIKYNKEGQDFQQLQEIQLEILSSVCQTLRKGGIITYSTCTIFDEENFQVID
                     KFLQRHPNFEQVTLKHAQADIVKDGCLMITPEQYQTDGFFIGQVRRVL"
     gene            complement(9573..10508)
                     /locus_tag="TV193_000368"
     CDS             complement(9573..10508)
                     /locus_tag="TV193_000368"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEL1512604.1"
                     /translation="MTRLIFMGTPQFSATVLQGLLEKPAYDILAVVTQPDRAVGRKKD
                     ITMTPVKKLALAHQLPVFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVT
                     FAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTD
                     NVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPA
                     REVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGA
                     LSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE"
     gene            complement(10575..12959)
                     /locus_tag="TV193_000369"
     CDS             complement(10575..12959)
                     /locus_tag="TV193_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEL1512605.1"
                     /translation="MQHIAQVIVDIPLMQTDKPFSYLIPDELLSLVKIGSRVHVPFGN
                     GNRLLQGFVIGFSSQSTQQLKAIWSVLDAEPVLNQEQVALAEQLRQTVFSYKITLLKA
                     MLPSLLNSHYDRLLTPTADLAAADLADVFSNGDSLLYSKLSPEQEGRVLRLIQSGKIR
                     ATYLAKDKKTIKTETYYQVNRLALQEHKISNRAKKRQALKAYLLANPQKDKLAKLYQD
                     YSREVVSYFVTNQLIELEERRVNRSEDYFNHIKAAPLLKLNQQQQQAVDQITKAVGRE
                     AKPFLLEGITGSGKTEVYLHVIAHVLEQGKTAIVLVPEISLTPQMTSRFISRFGRQVA
                     IMHSGLSDGEKFDEWQKIKTGQARVVVGARSAIFSPLENIGAIIIDEEHEATYKQESN
                     PRYHARDVALIRARHHKAALVMGSATPSIDSRARASKGLYQFIQLTERANPLASMPQV
                     EIVDFRDYIGQQEVSSFTPYLIDKLKERLARKEQAVLMLNRRGYSSFIMCRDCGYVDQ
                     CPNCDISLTLHMDTKTMNCHYCGFQRAIPKLCPSCQGKSIRYYGTGTQKAYDELKQVL
                     PEARILRMDVDTTRKKGSHEAILSQFGNGDADVLLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLHLPDFRASERTFQLLTQVAGRAGRADKPGEVLIQTYNPEHYAIQLAKKQDFEAFY
                     AYEMGIRRKLGYPPYYFTVGLTLSHKSEQEVVKKAYQLLTILKQGLSDQIRILGPTPK
                     PIARTHNLYHYQIILKYRFEDQLEATLNQILDWSQEQDNRELKVIIDQEPQSFM"
     gene            complement(13023..13340)
                     /locus_tag="TV193_000370"
     CDS             complement(13023..13340)
                     /locus_tag="TV193_000370"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEL1512606.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGAAPTQSFKSV
                     KSTLQALEEIESGNVVIHPDPAAKRAAVRARFEAERLAREEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(13365..13991)
                     /gene="gmk"
                     /locus_tag="TV193_000371"
     CDS             complement(13365..13991)
                     /gene="gmk"
                     /locus_tag="TV193_000371"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEL1512607.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKNGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKAKVPDGVFIFLTPPDLDELQDRLVGRGTDSQEVIAKRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIETEHFRVERVIGRYDQMIKTTKSLR"
     gene            complement(14153..15763)
                     /locus_tag="TV193_000372"
     CDS             complement(14153..15763)
                     /locus_tag="TV193_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEL1512608.1"
                     /translation="MLINIITLLVCGLIGVILGYALISIRLKSAKEAAELTLLNAEQD
                     AVDIRGKAKADAAHIKKTAQRESKASRKELLLEAKEEARKYREEIEQEFKSERQELKQ
                     LETRLAERALTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQAQVEKLEEDKRAEL
                     QRVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTDKTAKDLLAQAMQRMA
                     GEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDP
                     IRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPD
                     LIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDR
                     EVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGAR
                     NESVENYIKRLRDLEEIATSFDGVQSSFALQAGREIRIMVQPEKISDDEIVVLSHKVR
                     EKIENNLDYPGNIKVTVIRELRAIDYAK"
     gene            15920..16405
                     /locus_tag="TV193_000373"
     CDS             15920..16405
                     /locus_tag="TV193_000373"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEL1512609.1"
                     /translation="MPKEVIVESFELDHTIVKAPYVRLISEEFGPQGDVITNFDVRLV
                     QPNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKI
                     ITSSLEEIATSITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVT
                     S"
     gene            complement(16550..18001)
                     /locus_tag="TV193_000374"
     CDS             complement(16550..18001)
                     /locus_tag="TV193_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512610.1"
                     /translation="MSEKSKAFESEAESQNLELHEAKKMTIGEAVRKDSELKAGITED
                     DSVLDKYIKRHRNEVSSQKFDAKYMELDTASLDNFIKKQREELSKAGLVDVEPVDEAS
                     TEEKPAGETSFIEPLAARADTSAAATDSASDFTGQLADDAVSERPAEVESILSDSYAS
                     RRSKKKKPLFAILLATLTLVASAFALNHIYQLSKHKPQSKATVSKKARSKASTANQTN
                     KTKANAKAFEDLYKTFFTDNDKTTLKNSAFDQLPNLETALKRLEGTAYYDKAKEKVTG
                     LKKQVTAIQAVNGKFTTAAIVNGEKIAAEVKADANFDDLASDTLTTGNAKLDSLLQSS
                     IKAGREQLASRSATQAASTPAASALPASPAAPQVPAVPAPVAPMYGITGYDPSILQRD
                     LSRVPYNQAMIADTGNPAWAFNPGVLERIVATSQARGYISGNDYILEPVNIINGNGYY
                     NMFKPDGTYLFSLNCKTGYFVGNGKGHAEDLDY"
     gene            complement(18015..19169)
                     /locus_tag="TV193_000375"
     CDS             complement(18015..19169)
                     /locus_tag="TV193_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEL1512611.1"
                     /translation="MKEQFTLVATAAAGLEAVVGKELRALGFDCRVDNGKVFFEGDIE
                     AIAKANLWLRAADRIKIIVGQFPARSFEELFQGVFALDWEHYLPLGARFPIAKAKCVR
                     STLHNEPSVQAITKKAIVRKLQQHFHRPEHIPLQEVGAEFKIEVSILKDQATLMIDTS
                     GSSLFKRGYRVEKGGAPIKENMAAAILKLSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDRVQKVRDAAEKEANYDIELDISGFDIDGRMVELAKRNA
                     EEAGLADIITFKQMRLQDFRTDKINGVIISNPPYGERLLDDKAVDILYNEMVQVFAPL
                     VTWSKFILTSDDHFEQKYGQKADKKRKLYNGTLRVDLYQFYGERVKRNLI"
     gene            complement(19233..19601)
                     /gene="rnpB"
                     /locus_tag="TV193_000376"
     ncRNA           complement(19233..19601)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="TV193_000376"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(19614..19937)
                     /gene="gpsB"
                     /locus_tag="TV193_000377"
     CDS             complement(19614..19937)
                     /gene="gpsB"
                     /locus_tag="TV193_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEL1512612.1"
                     /translation="MTGIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYEYFNA
                     QIEALKAENEALKKAKAQVRDPLAGSSQAVSQPTRVAQSATNFDMLKRISKLEKEVFG
                     KQIIE"
     gene            complement(20059..20574)
                     /locus_tag="TV193_000378"
     CDS             complement(20059..20574)
                     /locus_tag="TV193_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEL1512613.1"
                     /translation="MTAILVTGYRSFELGIFSEKDKRVAIIKKAIERDLIAYLEEGVD
                     WFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQQLQQFRETDF
                     VKYSYPSYESPKQLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFL
                     NFERLNDIADE"
     gene            20650..21258
                     /gene="recU"
                     /locus_tag="TV193_000379"
     CDS             20650..21258
                     /gene="recU"
                     /locus_tag="TV193_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEL1512614.1"
                     /translation="MVNYPHNPIRQKVTPLQKQQKHKQVDFANRGMSFEASINATNAY
                     YLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAK
                     ETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQID
                     RGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN"
     gene            21245..23410
                     /locus_tag="TV193_000380"
     CDS             21245..23410
                     /locus_tag="TV193_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1512615.1"
                     /translation="MITINNPKILKFLKYTLGAILSLIIVTITLGGLLFAYYISSAPK
                     LSEAQLKSTNSSLVYDGNNHLIADLGSEKRENVTADSIPINLVNAIISIEDKRFFNHR
                     GVDLYRILGAAFHNLTSKTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKAYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYTQPETAQSRRNIVLQQMYAEKNITKAEYEAAIATPISEGLQPLQQRASYPKYMD
                     NYLKQVIEQVKAETNKDIFTSGLKVYTNIIPEAQKKLYDIYNSEDYVYYPDADFQVAS
                     TVIDVTNGHVIAQLGGRNQDTNVSFGTNQAVLTDRDWGSTMKPITDYGPAIESGAYNS
                     TAQTTNDSVYYWPGTHTQLYNWDRRYYGWMTIQAALMQSRNVPAVRALEAAGLSYAQS
                     FLSDLGINYPEMHYSNAISSNNSSSDSKYGASSEKMAAAYAAFANGGLYYKPQYVNKI
                     EFSDGTSKVIENKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAQIVETHGLSPDYVGTMAPDENFVGYTNRYAMAVWTGYKNRMTPIYGYSLEIA
                     SHVYRNMISYLTGGYSDDWTMPSGLYRSGGFLYLSGTYTNSSDYTSSVYNNLYGNNSS
                     ASSQSSDEDTTEDSHSEANDSTTSSSEQQSSSTDDKKTN"
     gene            complement(23453..24787)
                     /gene="pepC"
                     /locus_tag="TV193_000381"
     CDS             complement(23453..24787)
                     /gene="pepC"
                     /locus_tag="TV193_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEL1512616.1"
                     /translation="MSVLTETFTEQLYANYEANAKYLALENAITHNGLLKSLETRQSE
                     IDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLISEFKLEDFELSQAHTFFWD
                     KYEKSNWFMEQVIATADQALTSRRVKFLLDVPQQDGGQWDMVVALFEKYGVVPKSVYP
                     ESVSSSNSRELNQYLNKLLRQDAQILRDVISAGADHQAVQAKKEELLQEIFNFLAMNL
                     GLPPRQFDFAYRDKDNHYHADKGITPQAFYEKYVGLKLSDYVSVINAPTADKPYGKSY
                     TVDMLGNVVGSPEVRYLNLDMERFKELAIKQMQAGESVWFGSDVGQVSDRQKGILALN
                     TYDFQAGMDIQLSQDKAGRLDYSESLMTHAMVLTGVDLDDTGKPIKWKVENSWGDKVG
                     DKGYFVASDAWMDEYTYQIVVRKDLLTADELAAYEAEPQVLAPWDPMGALAK"
     gene            complement(25476..26300)
                     /gene="nadE"
                     /locus_tag="TV193_000382"
     CDS             complement(25476..26300)
                     /gene="nadE"
                     /locus_tag="TV193_000382"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEL1512617.1"
                     /translation="MTLQEDIIRQLEVKAVIDPKQEIRQSVDFLKAYLLKHPFLKTYV
                     LGISGGQDSSLAGKLAQMAIEELRAETGDEQYQFIAVRLPYGVQADEADAQKALAFIQ
                     PDQALTVNIKEAVDGQLRALEAAGLEISDFNKGNIKARQRMISQYAIAGQTAGAVIGT
                     DHAAENVTGFFTKFGDGGADILPLFRLTKRQGKALLKVLKADPSLYEKVPTADLEDKK
                     PGLADEVALGVTYQEIDDYLEGHTISAEAQARIEDWWHKGQHKRHLPITIFDDFWK"
     gene            complement(26297..27757)
                     /locus_tag="TV193_000383"
     CDS             complement(26297..27757)
                     /locus_tag="TV193_000383"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEL1512618.1"
                     /translation="MYRDDSLTLHTDLYQLNMMQVYFEQGIHNRNAVFEVYFRREPFN
                     NGYAVFAGLQRIVEYLEQLTFSETDLAYLKELGYSPAFLTYLRELRLELTIRSAQEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQEMDAAVWGTRAAIIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFKAYA
                     SVHKDCIFLVDTYDTLRVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKRVRQQLD
                     AAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QADGTMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTGVNVNDLEEIHM
                     FHPTYTYINKTVRDFDAVPLLVDIFDKGKLVYQLPSLKDIKAYARKEFDKLWDEYKRV
                     LNPQHYPVDLALDVWQNKMHLIDKIRKEACKRSDLI"
     gene            complement(28033..29427)
                     /locus_tag="TV193_000384"
     CDS             complement(28033..29427)
                     /locus_tag="TV193_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1512619.1"
                     /translation="MSTKEAKSTKELENGMVRGLQNRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGVFMFLMMRAIGEMLYYDPDQHTFINFITKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVASYVQFWFPAWPSWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKIVAILALIATAVFMVLTGFETHVGHASLANIVDHFSLFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPMRIVIFYVGALVSIMAIVPWYQLPTDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTKALR
                     INTLSRQGVPSRAIIASAVAVGVSALINILPGVADAFSLITASSSGVYIAIYALTMLA
                     HWKYRQSSDFMPDGYLMPSYQLTTPLTLAFFAFVFISLFLQKSTYIGAIGASIWILVF
                     GCYSQLKCKKALKG"
     gene            complement(29547..30464)
                     /gene="trxB"
                     /locus_tag="TV193_000385"
     CDS             complement(29547..30464)
                     /gene="trxB"
                     /locus_tag="TV193_000385"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEL1512620.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLRVGIIEQGAPGGQMNNTSD
                     IENYPGYDHISGPELSLKMYEPLEKFKVENIYGIVQRVEDCGDYKRVYTEDTHYDTKT
                     VIVATGAKHRLLGVAGEEEYTSRGVSYCAVCDGAFFRNQELLVVGGGDSAVEEAIYLT
                     QFAKKVTIVHRRDQLRAQKILQERAFANEKLDFIWDSVVKEIQGNDIKVSNVVIENVK
                     TGQVTSHDFGGVFIYVGLIPVTQMVSELGITNQEGWIVTDDQMKTSIPGIFAVGDVRQ
                     KQLRQITTAVGDGAIAGQGVYHYIESLSS"
     gene            complement(30524..30751)
                     /locus_tag="TV193_000386"
     CDS             complement(30524..30751)
                     /locus_tag="TV193_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEL1512621.1"
                     /translation="MLVEIFRFYLEGLLLAAITMVMLCLLWILWRAVTKKDKTILQRQ
                     AFLYEMIMVAILTIPILSFAFMSILVVLKAK"
     gene            complement(30861..31604)
                     /locus_tag="TV193_000387"
     CDS             complement(30861..31604)
                     /locus_tag="TV193_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1512622.1"
                     /translation="MIKVTHLTKSFSGQKILDDLTVTIEKGQVIALVGASGAGKSTFL
                     RSMNYLEQPDTGSITIDDFAVDFEHITKEDILTLRRKLAMVFQQFNLFERRTALDNVK
                     EGLKIVKKLSDQEATDIARAELAKVGLSDRENHYPRHLSGGQKQRVAIARALAMKPDV
                     LLLDEPTSALDPELVGEVERSIIDAAKAGQTMILVSHDMAFVYQVADRVLFLDKGKIL
                     EEGAPEQIFRHPKEARTKEFFANYAKTYI"
     gene            complement(31604..32407)
                     /locus_tag="TV193_000388"
     CDS             complement(31604..32407)
                     /locus_tag="TV193_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1512623.1"
                     /translation="MTSTFLTSGWAWYDKLISLIPEGKLFSWHAVFDAIPDIIRRLPI
                     TLGLTIAGAALGLFLALVFAIVKINRVRILYPIQAVFVSFLRGTPILVQLMLSYYGIP
                     LFLKFLNQRYGFDWNINAIPASIFAITAFAFNEAAYTSETIRAAIQSVHTGEIEAAKS
                     LGMTSAQVYRRVIIPNAAVVATPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGAD
                     YRYFERYISVALVYWGISILIEQAGRLIEYNMAIKAPIPTNNSKIGELR"
     gene            complement(32784..33611)
                     /locus_tag="TV193_000389"
     CDS             complement(32784..33611)
                     /locus_tag="TV193_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1512624.1"
                     /translation="MTKQLQRALFFLLASLGLLAVVTSHEVTARQKEVIRVATDAATK
                     PFTYRKKHSVTGYDIEVLKRVFKGSKKYRLSIEVVPFPSILAGIDAGRYQIGANNFGY
                     SKERAEKYLFSSPISASHYALATKGKQQYKSLADLSGKKTQGIAGSNYMLILEKWNQS
                     HPDQKPIHLTYASESTPFTQRLQLLENGQLDFLFYDAISLTTVAEEQGFDVHVTKLKE
                     QADTAKDGLEYYVFANDQKGKALQSFVNKRLAKLKKSGQLRKLSQAFLGGDFISKVN"
BASE COUNT         9808 a         8003 c         6471 g         9722 t
ORIGIN      
        1 acaaggataa aaaggaggac ctatgtcaaa gctatatcac aacattacag agttggttgg
       61 gaaaacccct attattaaat tgagaaacac cagtccagag gaggctgccg atatttatgt
      121 caagctagaa gcttttaatc caggctcttc agttaaggat cgcatagcac ttgcaatgat
      181 tgaagctgct gagaaagcag gcatgatcaa gccaggtgat acaatcgttg agccaaccag
      241 tggcaataca gggattggct tatcctgggt tggggctgca aaaggctacc gagtgctcat
      301 tgtaatgcct gagacaatga gtattgaaag acgtcaaatc attcaagctt acggagcaga
      361 gctcgtttta accccaggta gtgatgggat gaaaggtgcg attgctaaag cagaagagat
      421 tgccagagag accggtgctt ggatgccctc gcaatttgac aatcctgcaa atcccaaggt
      481 tcatgaagag acaacagggc aagaaattat cgcggttttt ggagaaaaag gacttgatgc
      541 ctttgtttct ggtgtgggaa ctggtggcac tatttctggc gttgcgcatg ccttaaaggc
      601 tgttaatcct gatatttcta tctatgctgt ggaagcagat gaatctgccg tcttatctgg
      661 tgaagagtct tctccgcaca agattcaagg gatttcagct ggctttatcc caaatacctt
      721 agatacaaag gcctatgacc acatcattcg agtagcgtca gaggctgccc ttgccactgc
      781 tcggtcaatc ggggctaagg agggctttct tgtaggcatt tcttctggag ccgctgttta
      841 tgctgctatc caagctgcta aggagcttgg aaaaggtaaa aaggtcttag ctatattacc
      901 agataatggt gagcggtacc tgtctactgc cctttatcag tttgattaga ataatcatat
      961 aagcaccagc cctagcagct agaataagct ttcaagcata aatcatcgct cttacttagt
     1021 caccattaaa ggccagtcag ctagcatatg gaaaaatgct tactttgatt cctttttaac
     1081 aataaacata gcataccacg cctaagcgcc ccagagcttc tagcttcttg gaaataggct
     1141 ttcctagccg ctttcaccac agtaaaaaag actcaagcta gtaggctaag atgttcaaag
     1201 aggactagca atcacaattg gctttttttg aagatagctt tgagataagt aaggtgactg
     1261 gtccagagct gatagcaaaa aaccgaggaa cagttcatat agctgtttct cggtttttta
     1321 tgtttccaag tctgtttacg atttttcctg cttaaagtgg tctaagcctt cctcaatcca
     1381 attgggtaag ctggcttcaa gaggcttaaa gccaatctta taacggctgt ttgaaaagcg
     1441 atgatgactt gacacatgat gcttttcctc ctccaaagtt ctcaaggaca ggctgacctt
     1501 atgactgtat tcgtcatagt caatgacctg aactaaaacc gcctcaccaa gtcttaggat
     1561 ctgatgaata ttatcaataa atcccgtctt aatttctgaa atatgaatga gacctgttgt
     1621 cccattttca agggcaacaa aggctccata gggtttgatt cctgtaatgg tcccatgcag
     1681 cttatcgcca attttcatca atcaaatacc tcgatggcct caatgacaac gtcctctttt
     1741 ggcttgtctt gtgcccctgt ttcgacagca gcaatgttat ccaagacctg ataagaggct
     1801 tcatcagcca actgaccaaa tactgtatgg cgacgatcca ggtaaggagt ccccccatgt
     1861 tcagcgtagg ctgctgcaat gtcctttggc cagccaccac gctctaattc cttttgagaa
     1921 taaggaaggc ttgtattttg gacgataaag aattggctgc cgtttgtatt tggtcctgca
     1981 ttagccatcg aaagggctcc gcgaaggttg tacaattcct ctgaaaactc atcctcaaag
     2041 ctttgaccat agatggattg cccacccatt ccagtgccag tcggatctcc accttgaatc
     2101 ataaaatctg caataatacg atggaaaata acaccattat agtagccttc cttagctaga
     2161 cctaagaagt tagcaactgt ttttggagca tgctctggaa ataaagccaa tgtcagctca
     2221 ccatgatttg ttttcatcac cactcttggt ccttcatggc cagccaaatc tagctgcgga
     2281 aaatgtaatt ctttgtcaat caaacctaat tcctccaagg catataaaat gccgttttct
     2341 tcaactgttt tagtaataaa atctgctttt tcttgtaatt gtgggtgaga aacccccata
     2401 gcaatgctga tgccagcata atcaaatagc tctaaatcat tgagctcatc accaaagacc
     2461 aggatatttt caggccttaa gcccaaatgc tcaacaacct ttgatacacc tagagcctta
     2521 gaggtgccct ttaggaccac atcagaggag tgatcatgcc accttactag gcgaagctgc
     2581 tcagccaatt caacaggtaa ttgcaggtca tctcccttgt cctcaaaggt ccacatttgg
     2641 tagacatcat ggtgctcatt gtaatccggg catacctcta gtgtggagta aaccttatca
     2701 atagcatcac taatcatctc gttacgagct gataagacag cctcgtgacg tcctgccatg
     2761 ccataatcaa tgccgactgc attggcccat tttttatagg ctacaacagt gtctgctggg
     2821 ataggtgcct gaaagataat gtttttttga ttgtccttca cataagcacc atttagctta
     2881 acacaataat ctgcctgtaa atcctgaacc tccttgggca caccatatct ggcgcgaccc
     2941 gaagcaattc ctgttaggat cccttttttc ttgagctctt tgaaaaccct ctggatagac
     3001 tctggcatat agcctgtgtt ctttacgcgc agggtatcat ctatgtcaaa gaaaaccatc
     3061 ttgattttct tggccttata ctttagtttt gcgtccatac tttcctccat gcaatagtac
     3121 tattatagca ttaatgatca tcttgaggca ctaaatgatg tcggaaagcg tatacaacag
     3181 cctgagtacg atcatcaacc tgcaatttgg ctaaaatatt tgacacgtga gtcttaactg
     3241 tcttcaagga aataaaaagc tcatcagcaa tggtctggtt atcatagccc ttggccaata
     3301 aatgcaaaat atcgtattca cgcgctgtaa gctcttcatg taaattaggc tgctgatcat
     3361 gtgccttaat cttcttgtca acctccgttt caatggcaag ctcgccctta gcaacctttc
     3421 taatggcatt taagatttca gctgcacttg atgtttttaa catatagccc ttagctcctg
     3481 catcaatgac agggtaaatt ttttcattat caagatagga ggttaacacc aacacccttg
     3541 cttccttcca tttggagagt atttctaggg tcgcctctac acctcctaat tcaggcatta
     3601 ccaaatccat aaccacgaca tctggtctca attcaagggc aagctcaact ccctcacgac
     3661 cattagaagc ctcacctatg acatcaacat cttgctgcaa atttaagaag ctttttaagc
     3721 ccattcggac catttcatgg tcatcaacta atattacggt tatattactc atcttcatct
     3781 cccatcacaa gtggcagtct aatgtccatc gaaacgccct ttcctttttg actaatcaaa
     3841 cgaagcgttc cagccaggtc attcacacga tcttcaatat ttttaaggcc atagcttaat
     3901 tccctaacct gacccatgtc aaaaccaacc ccattatcaa ccatttttag ctgtagttct
     3961 gttggtgttt ggttcaagta cacctcaagg cggctcgcct tagcatgctt gagggtattg
     4021 ctgataaatt cctgagcgat cctaaagaga ttatcctcta tggcctttgg cagagtgcca
     4081 atattttctt tatagacaac ctcaatgccg cttttatcag ttagttcctt gagaatcatc
     4141 gtaaagccct ctgacaggct acgatttgcc aattctgtcg ggcgcaggtg caataataaa
     4201 atgcgtaaat cattttgagc attttgcagc atggcttcaa cagtaactaa ttgttgctgt
     4261 agctgctcct tatccatctg atctaggctc atagaaaccc ctgacaaaat catcgacgaa
     4321 gcaaacaatt cttgactaac agtgtcgtgc aggtctctag cgattcgttt acgctcctgt
     4381 tgaataattt tttgactatc taaaatataa gcattctctt ttttctggat attggttgtt
     4441 atatgagaca ttttcgcaga aagtctggtc aaattcgtgt tgatttcaga ggtctcctcc
     4501 aaatgaattc tttgattgtt gagaatcctg cgtaaatttt tattgatgct ccgcttgcta
     4561 ttatcatcta aaataatcca caacaaaagc aacagcaagg ttacagagat gataagcagc
     4621 acaactgaaa acaccaagcg ctctagctgc cataaatggc tccgcaagta gtcaaaggtg
     4681 atccccagat tatccatcac aacaaaaaca attgataaaa tggttatagt cgaataaagc
     4741 cagaccaaag cataatacct ttttttcatc gtctagccac ctcgacattt cctgctatag
     4801 tggatacgat aatcttaacc ttctttaaac tgctgtcctc ggcctctcct agggtgatgg
     4861 attcatttcg taaatcgtac tcttgaagct caaaaaaatc aacactagca tagatagagc
     4921 tgacctctaa ggtaacagcc acatcaatag gcactaggat ctttgtgttg ccaaagatct
     4981 ttctgataat gatgacattg tccattccag tcacaatcac atttgtcaga tcaatcgtat
     5041 cattgccaga ggcacgaata atattgatat cctcaaagga ataataatca ctttcatagt
     5101 tagctgcgcc aagccattga tttttgacct gtcgcacagt cattttttct tctgcaaacc
     5161 gaatgagggc aaatcgattc ttctttttta cctgtgaaaa atgattgata atcacataca
     5221 caatccccaa cagaaccgcc ataataacat aagggttcag cataaaaatt aagaataaaa
     5281 gcaataagct aactgttagc aaaaagctat tgcgggtatc ttgattataa aaacgcagag
     5341 ccaataaaat caagaccaaa attaaaataa agcttgataa gtcgttggcc aaaatggtca
     5401 taatccccat agccagcagc atgcattcaa caagcagaaa gaattgaaat tttttcatta
     5461 gactccttcc attaccctga cattttatca aaaattaagc aaaaattcac ccttgagtgg
     5521 cattctagta aaaaagaata cctagcttag caactatggg caagccagat attctatatc
     5581 ctatttacgt ttacggtgtt gtaacagcgt cattttgacc taattcggta tgactgcttg
     5641 agtctgttgt atctccagct gatggattag gagccgaggt atcagagctc gatgagctgc
     5701 ttgatgcacg tgtctcctca gggtagaggt agaggctaat atcacccttt tcagaaaggc
     5761 taatctgggt accataatac ggtgtttgcc cactgacaac cgcctttgag cttggggagc
     5821 tcacctgcac aaagcctgtc ggagagctgg agcttggtac ataggccttg attcttgcgg
     5881 catcaattcc taaagctgtt agtgtattga ctgcatctgc atagctgtac tcagttacca
     5941 ttggcatgat gactgtatca cccactgcta cactgagggt aatcttggat ttaccagctg
     6001 ggttaaattt ttctcctgcg cttggagact ggctaataac ggtgttttca gggtattcat
     6061 ttgtcacgat acgctcaatc ttgatttttg actttggtac gccataggtc tcagtcagac
     6121 tggtcatcac atcttgataa tcctgtccct tataattttc catctcaaag cctttatttc
     6181 cgatcgaaag gtaaaggtca acgctggagc cttttcgctt agctgagcca gcttgaggat
     6241 ttgtcttaac cacctgatcc tcactaactg tgtcactttc aatctgatgg accttaccga
     6301 cctttagtcc cgcctcctcc aagacctgct tggcagcatt gagactagag cctgtcacat
     6361 caggaacctt aaccgtagtt ggcttggtca agaccaaata agcaaaaaga gccacaccaa
     6421 caacaaaaaa ggaaaacaag atttttaaga gtgttcctag aaaacgccca ttttttttct
     6481 ttttttgagg cttttgcaga gtatccatct ggctagtctg ctcaagtcta gcatcaactg
     6541 ccgcagatgc ctgactagca tttgatacct taggtgctgt tacaggagtc ggtgttacct
     6601 ttggcaaggg ctttgtgctt tcgacatcat caaagacaac cttacgctca cgactgcggt
     6661 tatagctaag ggctgtcatc aaatccctgc tcatctcaaa ggtcgagcga taacggtcac
     6721 ttagcttttt ggcagtagcc cgaataacga cgttttccaa ggcttgaggc acattaggat
     6781 tttcatcaat gatagagggc agcggctttt gaaaatgctg caaagcaatc gtcacagcgc
     6841 tatcgccatc ataaggaata tgccctgtta gcatttcaaa gagcataatt cccatcgcgt
     6901 aaatatcact ttgaatcgtc gctttagaac cacgcgcttg ctcaggtgag aggtaatgca
     6961 cacttcctag catagaattt gtctgggtta gactggtctc tgcaaaggca acggcaatcc
     7021 caaaatctgt aaccttaaca acacttgatt tggtcaaaag aatgttttga ggctttaaat
     7081 ccctgtgaac aattcctttt tggtgggcca gagtcatggc agaaagaacc tcttccatga
     7141 ttctcaccac ctcattgtta gataatggcg catgatcctg aatgtatttt ttcaagtcag
     7201 agccatcaac atattccatt actaaaaatt gctgtccgtc ttcctcgcct atatcccgaa
     7261 tggcaacaat attggggtga tttaattcag ccatggctcg cgcttctctt tgaaaacgcg
     7321 caacagcaac ctgatctgtt tgataattgg tccgcaagac cttaatggca acgtcctcat
     7381 tatccagaat caaatcgttt gctaaataaa catccgccat accaccgcgg cctatagatt
     7441 ttagaatgcg ataacgacca gcaaatagct tgccaatctg aatcattctg cttccccgct
     7501 ttccttatgc accaaagcaa cggtgatgtt gtctaggcct cctctttggt ttgccaggtc
     7561 aatcaaggct tgatttttct catcaaggct gatgtcttga cataatatgt caacaatctc
     7621 ctcattagca atcatattgg ttaagccatc actattaatc actaggtaat cgcccttttc
     7681 taaaaccttg acacctaagt ctggctctac cggtgaagct tgacctatag attgtgtgat
     7741 gatatttttt tgtgggtggc tagcagcctc ctcttcggta atctgaccag ccttcactag
     7801 ggcattaacc aaggaatgat cactggttaa aagactataa tttccctcat gaaccaagcc
     7861 gatacgagaa tcgccaatat gggcataaat cgcattagaa tctactagag caactgcctc
     7921 aacggttgtt cccattccct tatagtcttc agattgtccc aagtcgtaga tacgttggtt
     7981 ctctgcttcg atggttgtta acaaccaatc cttgatctga ctaagctcag taaaatctgt
     8041 cttaacccac tctctaccta ggtctgtaac ggtcatctca ctggcaatat ttcctgccct
     8101 atgacctccc ataccatctg ctaggataac aagggtaatg ccttttttat tatcaaattt
     8161 gttgataaaa tcttgattgt ttgagcgctt ttgcccaata tcggttttta atgaaatctt
     8221 catataatct tttctgacta ggtcagtctc ctcctaaata ctacaagact cgtctgactt
     8281 gcccaataaa gaagccatca gtctggtatt gctctggtgt aatcataaga caaccgtcct
     8341 tgacaatatc tgcttgtgca tgcttgagtg ttacttgttc aaaattagga tgacgttgta
     8401 aaaatttgtc aataacttgg aaattctctt catcaaaaat cgtacaagtg ctataggtta
     8461 ttataccacc ttttcgcagc gtttgacaaa cgctagacaa tatctccagc tgaatttcct
     8521 gcaattgctg gaagtcctgc ccttccttgt tgtatttaat atctggctta cgcctgatga
     8581 ggcctatacc agagcaggga gcatcaacta aaatcttatc aaagctgttc ttcgcaaaat
     8641 gcttatgaac ctctctagca tcaagcacct tagtttcaat ccgatctgct acccctagac
     8701 gcttagcatt ttcattcact aaggccagct tgtgctcata caaatcaagg gccactactt
     8761 tgccgctcgt caaataagag gcaatgtgag ctgttttccc tccgggtgca ctacaagcat
     8821 ctaaaatcat ttcctgccct tgaatatcca gcgtcggggc aactagctga ctggtctcat
     8881 cttggatcgt aatgtcccca ttgatgaaat aactgctggc agcaaaattg ccagctctct
     8941 tggtcagacc agtcctagca agtaatgatt gctctgatcc tgttgcctgc ttgatctcat
     9001 caagctttgt cagatctgtg acacgtatgc tggctctgct tctcacaaaa agactttcca
     9061 tgattgctac agctcgctcc tcgccaaatt ggtcgatcaa ttttttgact agccagaccg
     9121 gtactgagta agcaacagca tagtatttgt tttttcgctt gatgctcttg atatctggta
     9181 agggcttatt ggtcagctgg cgcaaaacgg cattgaccag cttatctgct cctctgccat
     9241 gagctctcgc cttggcaaga ttaacagcgt cattaacaat agcatgagca ggcaccttgt
     9301 ctaggtaagc cagctggtaa aggctaagca tcaagagata ataaacccat ttatccagcc
     9361 tgtctcggtc ctcaatatag tgagccagat accattctag ggttatcttc ctagagatag
     9421 tcccgtaaac aatctctgtg actagagcct tgtccttatc acttaaaaac tgattcgcca
     9481 gctggtgctt caaggcaagg ttagaatagg ctccatgatc aaaaatatcc tcaacgataa
     9541 gcagcgcctg tcctctagct gattttttcc aatcattcgc caaggacatc acccacctct
     9601 aggcttctgc caataccatt taaaaagtca acaataggca tctttggctt gcctgctggt
     9661 tgaacgagcg tcaaggatag agccccctca cctgctgcta cgaccaatgc ttttttagtt
     9721 ttagcgatga tttgcccagc agatccagag ccttcagcca attcagcctc ataaattttg
     9781 aagcgctgcc catctaataa ggtatgagcc accggccaag ggttcattcc tctgatatga
     9841 ttaaacacct ctcttgctgg ctttgaccag tccagtcttt cttcttctgc tgaaagattg
     9901 ggagaaaagg tggcttggct atggtcttga ggaactggct ttaggtcacc agacaagtaa
     9961 tcaggcaagg ttttcaataa taaatctcgt cctagaatgg ccagcttatc aaacatggta
    10021 ccaacattat cagtatctaa aattggaagg cttgcgcttg atatcatatc cccagcgtcc
    10081 atctccttaa ccatctccat aatggtaact ccagcttcct tgtcaccatt gataatagca
    10141 taatggatcg gagcgccacc acgatattta ggaagtaagg acgcgtgcac attaacagca
    10201 aatgtcaccg aatccaataa gactgttggt aaaaattgcc caaaggctgc cgttacaatc
    10261 ccgtctgctc ctaatgccat gatatctgct agctcctgtg aaccagatag cttctcaggc
    10321 tgaaaaacag gcagctgatg tgcaagcgcc agctttttaa caggcgtcat tgtgatgtct
    10381 tttttgcgac caaccgcacg atcaggctgg gtcacgaccg ctaaaatgtc ataggctggt
    10441 ttttctagta agccctgcaa aacagttgct gaaaattggg gagtgcccat aaaaattaat
    10501 cttgtcatct atgtcctcta ttttctttct ttttcattat agcatagctt ggcgcaaagt
    10561 ccggtaaaga acacttacat aaagctctgt ggctcctgat caatgataac ctttagctcg
    10621 cgattatcct gctcttggct ccaatcaaga atttgattca gggtagcttc aagctgatcc
    10681 tcaaagcgat acttcaaaat aatctgataa tggtaaagat tgtgcgttct tgcaattggc
    10741 tttggcgttg gccctaatat tctgatctga tcagacaagc cctgcttcaa tatggtcagc
    10801 agttgatagg cctttttgac cacctcttgc tcactcttat gcgatagggt cagacctact
    10861 gtgaaataat agggaggata gcctagcttt cgtcgaatcc ccatttcata agcgtaaaag
    10921 gcttcaaaat cctgcttttt ggccagttga atcgcgtaat gctcaggatt gtaggtctga
    10981 atcaggactt cacctggctt gtctgcacgt cctgcacgtc ctgcaacctg agtcagcaat
    11041 tgaaaggttc gctccgatgc cctaaaatca ggtaaatgca aggaagtatc tgcatttaaa
    11101 acacctacta gggtgacgtt gggaaaatcc aacccctttg caatcatttg tgtcccaagc
    11161 agcacatcag catcaccatt tccaaactgg cttaaaatag cctcatggct tcctttttta
    11221 cgtgtcgtgt ctacgtccat tcgtaatatt ctagcttccg gcaacacttg cttgagctca
    11281 tcataggctt tttgcgtccc tgttccataa tagcgtatgc ttttgccttg acagctaggg
    11341 catagcttcg gaatagccct ttgaaagccg caatagtgac aattcatggt tttcgtatcc
    11401 atgtggaggg ttaaggaaat atcacaattt ggacattgat caacatagcc acaatctcga
    11461 cacatgataa agctagagta gccacgcctg ttgagcatca aaacagcctg ctcttttcta
    11521 gcaagacgct ctttgagttt atcaatcaaa taaggggtga agctgctaac ctcctgctga
    11581 ccaatataat ctcgaaaatc aacaatctca acctgaggca tactggcaag aggattggct
    11641 ctctcagtca gctggataaa ctgatacagt cccttgctgg ctctagcgcg actatcaata
    11701 ctaggggtcg ctgagcccat cactaaggca gccttatggt gccttgcacg aatgagagct
    11761 acatctctgg catggtatct gggattagat tcctgcttgt aggtggcctc atgctcctca
    11821 tcaataataa tggctccaat attttctaaa ggtgaaaaaa tagcagagcg agcaccgacc
    11881 accactctag cctgccctgt cttaattttc tgccattcgt caaatttttc tccatctgac
    11941 aaacctgaat gcataatagc gacctgtctt ccaaagcggg aaataaatcg agaggtcatt
    12001 tgaggcgtga gggagatttc tggcactaag acaatagctg tctttccttg ctcaagcaca
    12061 tgcgcaatca catgaagata gacctctgtc ttgccagagc ctgtaatacc ttccagtaaa
    12121 aagggcttag cctctctgcc aacagccttc gtaatctggt caacagcttg ctgctgctgc
    12181 tgattaagct ttaagagtgg ggctgccttg atgtgattga aataatcctc actgcgattg
    12241 acacgtcgct cctcaagctc gatcagctgg ttggtcacaa aatagctaac aacctctcta
    12301 gaataatcct gataaagctt ggctagctta tctttttgtg gattggctaa caaataagcc
    12361 tttaaggctt ggcgcttttt agcccgattt gaaatcttat gctcctgtaa ggctaatcta
    12421 ttgacctgat agtaagtctc ggttttgatt gtctttttgt ccttggctag ataagttgcc
    12481 ctaatcttac cagactgtat cagcctaagg acacgtccct cctgctctgg acttagctta
    12541 gaataaagca aggaatcccc attagagaaa acatcagcaa ggtcagccgc agctaagtca
    12601 gctgtcgggg tgagcagccg atcgtaatga gaattaagta ggctaggaag cattgccttt
    12661 aagagggtga ttttgtagga aaagactgtt tgtcgtaatt gctctgctaa tgccacctgc
    12721 tcctgattta aaacaggctc agcatctaaa actgaccaaa tagccttcaa ttgctgcgtt
    12781 gattgactag aaaagccaat aacaaagccc tgtagcaacc tattgccatt accaaaaggc
    12841 acatgaacgc gagaaccaat cttaaccaga gataatagct catctggaat aagataagaa
    12901 aagggcttat cggtttgcat caagggaata tcaacaatga cctgtgctat gtgttgcatt
    12961 ttgacttcct ttctatcaag aaatggacct gcaatatgaa aaaaactaag attgactcaa
    13021 ccttagattt tttctccctc ttcttctttt tcttttgcaa tctgctcttt tattttacgc
    13081 tcttcttctt ctcttgctaa acgctctgcc tcaaaccttg cacgaacagc cgcacgctta
    13141 gcagcaggat ccgggtgaat cacaacattg cctgactcaa tctcctctag tgcctgaagt
    13201 gttgatttga cagacttaaa ggactgtgtc ggtgcagcac ctgcttctaa ttcatgagca
    13261 cgcttggcct gtaaaataac aagtgaatat tttgatggga ctttatctaa taaagtatca
    13321 attgaaggtt ttaacatcat gggctttact cttttctatt tctatcatct gagagatttt
    13381 gttgttttaa tcatttgatc atagcgacca atcacacgct caacgcgaaa atgctcggtc
    13441 tcaataatac gcttgacacg ctctgcagct aaaggaacct cgtcgttgac cacagcataa
    13501 tcatactctc gcatgagcgc aatctcttcc ttagctcttt cgatacgctt ggcaatcacc
    13561 tcttggctgt ctgttccacg accaaccaaa cggtcctgca attcatctaa gtctggcggc
    13621 gttagaaaaa tgaagacacc atcaggcacc ttagccttga cctgcaaagc accctgtacc
    13681 tcaatttcca aaaagacatc aatgccctta tcaagggttt cgttaacata ggttaaggga
    13741 gtgccatagt aattgccgac atactctgca tattctagca tttgaccatt ttttattagc
    13801 tcttcaaatt cttctcgtgt gcggaagaaa taatcaaccc catcaacttc acctggtctc
    13861 tgtggacgtg tcgtcatcga aacagaatat tcaaatttat gatctggcgt tgaaaaaatc
    13921 tcttgtctca ccgttccctt tccgacacct gaggggccag agaaaacgat taacaaaccg
    13981 cgttcagaca ttgtgttctc cttattgatt gctttctaat agtttatcaa aaaggctatc
    14041 gtttttcaag acaattatca gcccaatcct aagaaagaaa aggaagagat agacgccttc
    14101 tcaaagctag aggctaaact ctggcttttg aaaagcatac actctttcct ttttatttcg
    14161 cataatctat tgctcgcaac tcacgaataa cagttacctt gatatttcct gggtaatcca
    14221 agttattttc aatcttttct cttaccttgt gtgagagaac cacaatctcg tcatcagaaa
    14281 tcttttctgg ctgaaccatg atgcgaatct cacgaccggc ttggagggca aagctacttt
    14341 gaacaccatc aaagcttgtt gcgatttctt caaggtcacg aagacgcttg atatagtttt
    14401 ccacagattc attgcgggca cctggacgag cagagctaag ggcatcagca gcagctacca
    14461 gaactgcaat aaccgaatcc ggctcgacat cgccatgatg gctggctatg gtgttcacaa
    14521 caacagggtg ctccttgtac ttgcgagcaa actccatacc aatctcaacg tggcttcctt
    14581 caacctcacg atcaatagcc ttgcccatat catgcaagaa acctgcgcga cgtgcaagtg
    14641 ccacattttc accaagctcg ccagctaaaa taccagctag cttaccaacc tcgactgagt
    14701 ggcgtaaaac attttgacca aatgaggtac gaaactgtaa gcgccccatg atcttaatca
    14761 aatccgggtg gaggttaggt gcaccgatct cataggcagc agcctcacca tactcacgaa
    14821 tcctattgtc catctcaaga cgatttttct caaccaattc ctcgatacgc gccgggtgaa
    14881 tacgaccatc agcaatcaag gactctaggg tcatacgagc aatctctcga cgaatagggt
    14941 caaagcctga taaaacaacc acttccgggg tatcgtcaat gatcacatca atccctgtca
    15001 gactctctag agtacggata ttgcgaccct ctcgaccgat aatacgccct ttcatgttat
    15061 catcaggcaa gtgcacactt gtaatcgtct gctcagtcac atactcacca gccatacgtt
    15121 gcatggcctg tgctaacagg tccttagcag tcttgtctgt cctgtccttg atgtcacgct
    15181 ctgcatcacg aatgcgtgtt gcgatctcat gcgtcagctt gttttcagtt tccatcagga
    15241 taacctcacg cgcttctgca atggtcatag cagcaactcg ttggagctct gctcttttgt
    15301 cttcctcaag tttttcaacc tgtgcctgtc gctcatcaat gtgcttagat ttatcggtca
    15361 gactttgctc tttgctatct agtacttttt ctttacttga tagattttca tccttacgat
    15421 caagagttag agcacgctct gccaagcgcg tctccagctg tttaagctct tgtctttcag
    15481 atttaaattc ctgttcaatt tcttcacgat actttcttgc ctcttccttt gcttctaaaa
    15541 gtaattcttt acgacttgct ttactttcac gttgtgctgt ctttttgata tgagcggcat
    15601 cggcctttgc cttgccacga atatcaacag catcctgttc agcgtttaaa agagtcaact
    15661 ctgcagcttc cttcgcagac ttgagtctaa tcgaaataag tgcataacct aatattacac
    15721 caatgaggcc acagacaagt aacgttatga tattaattaa catgtcttta cctcaataat
    15781 agtttagttt tcattaacag aaagccatct cttagtctat cataaaatga agatttagac
    15841 aatttaaaat ccacctacat ttttctaaaa tctagtgatt ttatgttatg atattgataa
    15901 aaataaaaag gagtttctta tgccaaaaga agttattgtt gaaagctttg agcttgatca
    15961 tactattgtt aaggcaccct atgtacggct aatctccgag gaatttgggc cccagggaga
    16021 tgtgattaca aattttgatg ttcgacttgt tcagcctaat caggctgcca ttgagactgc
    16081 cggtttacat accattgagc atttattagc caagctcatt cgtcaacgca ttgatggaat
    16141 gattgattgc tccccctttg gctgccgcac aggctttcac ctcatcatgt ggggcaagca
    16201 tagctcaaca gatattgcta agatcatcac gtccagccta gaggaaattg ctacaagcat
    16261 cacttgggag gacgttcctg gcacaaccat tgaatcctgc ggcaattata aggatcacag
    16321 cctttttgct gctaaggaat gggcacagct tattctcaag caagggatct ctgatgatcc
    16381 atttaaccgc catgtcacct cataaaacga aagcctctct tttctgctaa tgtgaaggag
    16441 gcttttaatg tattcaaaaa ggtgccaaag gcaaggctca atgcccttac ctttagcacc
    16501 tgtgataact agagtatcca gttcaggatc acaccttgtc ttctaagcat taatagtcta
    16561 agtcctctgc atgccccttg ccatttccga caaaatagcc tgttttgcaa ttcaatgaaa
    16621 agaggtaggt gccatcaggc ttaaacatgt tgtaatagcc attcccattg ataatattga
    16681 ccggctctag gatataatca ttgcctgaaa tatagcccct tgcttgtgag gtagccacaa
    16741 tacgctcaag cacacctgga ttaaaggccc aagcagggtt tcctgtatca gcaatcatag
    16801 cctgattgta gggcacacga gacaggtcac gctgcaatat tgaagggtca tagcctgtaa
    16861 tgccatacat tggagccact ggagctggta cagcaggaac ctgcggagct gcagggcttg
    16921 ctggtaaggc agaagcagct ggagtgctag ctgcttgggt agcagacctg cttgctagct
    16981 gctcacgacc tgccttgatg cttgattgta gcaatgaatc aagttttgca ttaccagtgg
    17041 ttagcgtatc actagctagg tcatcaaaat tagcatcagc tttgacctca gctgcaatct
    17101 tttcaccatt gacaattgca gctgttgtaa atttcccatt aaccgcctga atagctgtta
    17161 cttgcttttt cagcccagta accttttcct tagccttgtc ataataggct gtcccttcaa
    17221 gcctttttaa agcagtctcc aaattcggta actgatcaaa ggcgctattt tttagggttg
    17281 ttttatcatt atctgtgaaa aatgtcttgt aaagatcttc aaaagcctta gcattagcct
    17341 ttgttttgtt ggtctgatta gctgttgatg ctttgctcct tgctttttta gaaacagtag
    17401 cctttgactg aggcttatgc ttagacagct gatagatatg gttgagggca aaggctgagg
    17461 ctacaagggt tagcgtggct aacaaaatag caaacagagg ctttttcttt ttagacctac
    17521 gactagcata gctatctgat aaaatactct ctacttctgc aggtcgctcg ctaactgcgt
    17581 catcagctag ctgcccagta aaatcactag cagaatcagt agctgccgct gaagtgtcag
    17641 ctctagctgc tagaggctca atgaatgagg tctcaccggc tggcttctcc tctgttgaag
    17701 cctcgtccac tggctcaaca tcaactaagc cggctttgct gagctcctct ctttgttttt
    17761 tgataaagtt atccagactt gctgtatcta actccatata ctttgcatca aacttttgtg
    17821 atgacacttc gttacgatgc cgcttaatat atttgtctaa aacactatca tcctcggtaa
    17881 tccctgcttt tagctctgag tccttgcgta ctgcctcacc gattgtcatt tttttggctt
    17941 catgaagctc caaattttgg ctttctgcct ctgattcaaa tgctttgctt ttttctgaca
    18001 cgttttttac ctctctatat cagattgcgc tttaccctct ctccataaaa ttgatacaaa
    18061 tcaaccctta gagtaccatt ataaagctta cgttttttat cagctttttg accatatttt
    18121 tgttcaaaat gatcatcact cgtcaaaata aacttgctcc aggtaactaa tggagcaaag
    18181 acctgtacca tctcattata caagatgtct actgctttgt catcaagcaa acgctctcca
    18241 taaggaggat ttgaaatgat gacaccgttt atcttgtctg tacggaaatc ctgcaagcgc
    18301 atttgcttaa aggtaatgat atcagccaag ccagcctcct cagcatttct cttggcaagc
    18361 tcaaccatac gaccgtcaat atcaaagcct gaaatatcca gctcaatatc ataattagcc
    18421 tctttttcag cagcgtcacg aaccttttga acacgatctt tgtccaccca gctccattcc
    18481 tcaaaggcaa aggagcgatt aaagccagga gcgatattca ttccgatgag agccgcctcg
    18541 atacaaaagg tccccgatcc acaggtggga tcaaccaagg gcttatccgg aaaccaatta
    18601 gacagcttga ggatagctgc tgccatgttt tccttaatag gagctccccc tttttccacc
    18661 cggtagccac gcttaaatag gcttgagcca ctagtatcaa tcatcagggt agcctgatcc
    18721 tttaagattg agacctcaat tttgaactca gcccccacct cttgaagggg aatatgctcc
    18781 ggtctatgaa aatgctgctg caattttctg acaatggctt ttttggtaat ggcttgaaca
    18841 cttggctcgt tgtgcagggt tgacctgaca cacttagcct ttgcaatagg aaacctagca
    18901 cctaagggca aataatgctc ccaatccaag gcaaatacgc cctgaaacag ctcctcaaag
    18961 cttcgtgctg ggaactgacc tacaataatc ttaatacggt cagccgctcg cagccaaaga
    19021 tttgctttag caatagcttc aatatcgcct tcaaagaaga ccttgccatt atctactcgg
    19081 cagtcaaatc ccaaggccct taattcctta cccacaacag cctctaggcc agctgctgca
    19141 gttgctacta atgtaaattg ttctttcata tgactctttc tatcctaacc aaataaaagc
    19201 tagcatatgc tagcttaacc tattatgcaa ttttctataa gccatgtttt gttccagaaa
    19261 taactaggta ttatctcctt cgataatcat ctgtctactg tttgtcaaca gtcaggatag
    19321 cttgttcgtt tccaactatc ccatgcccct accaaagttt gggttgctag cttgaggggt
    19381 ttaccgcgtt ccacttttta cgtttccata aaaacttcgt cactgtggca ctttcagagc
    19441 tactctggca tatcaaggac ttagcctttt cactcgccgt aatgtgtcaa acacatccct
    19501 aggcttattt gttcgcctag cacaaacact accagcatca cagccggtgc tagcatggac
    19561 tttcctcata gtattgcaat actacgcgat tatccaaaaa ttgcacatct acattactca
    19621 ataatttgct ttccaaaaac ctctttttcc agcttgctaa tgcgctttag catgtcaaaa
    19681 ttggtggctg actgtgctac tctggttggc tgtgataccg cctgagagct gcctgctaaa
    19741 ggatcacgca cctgagcctt agcctttttt aaggcttcat tttcagcctt tagggcctcg
    19801 atctgagcat tgaaatactc ataatccttg atgacgttat caaggaattc gtcgacctcc
    19861 ttcttatcaa agccacgcat actggtctta aattcttgct caaaaatgtc ctttggacta
    19921 taaattatac ctgtcattct atactctcca aacggtcaat ctttttcaaa tatcaaactt
    19981 tgatatcact acttatgata cagaaaaata aattaaaaag caagtattta aataccagtg
    20041 atttttaaat atcactagct actcatctgc aatgtcattt aaacgctcaa agtttaggaa
    20101 agaaaggggg taacagggct gctccttcat agctgctacc aaatagctta ggcgcgtttc
    20161 gtgctcacta tcataaaaaa gataggctcc gtctgtattg tgaatcaaaa agtgatggta
    20221 gctctttagc tgtttagggc tttcatagct gggatagcta tatttgacaa aatcagtctc
    20281 ccgaaattgc tgcagctgct gctgattgcg atcattccaa gtgctgccat gcgtttcaaa
    20341 ggcaaaaata gtcgctgtct ttaaggggta ggtctttttg aggtcattag ctacctctaa
    20401 agcccactgc tcaaacccta aattcccagt aaaaataaac cagtctaccc cctcctcaag
    20461 ataagcaatc agatctcttt ctatcgcttt tttgataatg gcaactcttt tatccttttc
    20521 actaaagatg cccagctcaa aacttcgata gcctgttacg agaattgcag tcattagatg
    20581 ttatcctttc aaaaatatgt tataatgtga atgcttaaat tattattaag tcatgatgtt
    20641 aggagaacaa tggttaacta ccctcataat cctattcgcc aaaaggtgac ccctcttcaa
    20701 aagcagcaaa agcacaagca agtagacttt gctaatcgtg gtatgtcctt tgaagcatcc
    20761 attaatgcaa ccaacgctta ttacttggcc aagggcattg ctgtcattca taaaaagcca
    20821 actccgatac agattgtcaa ggtagactat ccaagacgta gtcgagccaa gattgttgag
    20881 gcttatttta agcaggcttc aacgaccgac tattctggta tctacaaagg gcattatatt
    20941 gattttgaag ctaaggaaac aagacaaaaa acagctatgc caatgaaaaa ctttcacgcg
    21001 catcagattg agcacatggc tgctgtttta aagcaaaaag gcatttgctt tgtcctcctt
    21061 cactttgcga cactaaagga aacctattat ctacctgcca aagcactcat tgatttttat
    21121 cagattgata ggggcaacaa atcaatgcca cttgattata tcagaaaaaa cggctttgag
    21181 gtcaagctgg gagcatttcc acaggttcct tatttagata ttatagaaca aaaattttta
    21241 ggcggtgatt acaattaaca atccaaaaat ccttaaattc ctgaagtata cattaggtgc
    21301 tatccttagc cttatcattg tgacaattac cttaggtggc cttttgtttg cttactatat
    21361 cagcagtgcc cctaagcttt ctgaggccca gctcaaatcg accaattcca gtcttgttta
    21421 tgacggtaat aatcatttga ttgctgactt gggctctgaa aagcgtgaaa atgttacagc
    21481 tgacagcatt cctattaatc tggtcaatgc tattatttct atagaagaca aacgcttttt
    21541 taatcatcgg ggggttgatc tctatcgtat cttaggtgca gcctttcaca atttaacaag
    21601 caaaacaacc caaggggggt ctacacttga tcagcagctg attaagctag cctacttctc
    21661 gacaaacgag tctgaccaga ccttgaagcg aaaagctcag gaggtttggc tggcccttca
    21721 aatggagcga aaatatacca agcaagaaat cctgaccttc tacatcaaca aggtttatat
    21781 gggaaatggt aattatggta tgctgacagc agccaaggct tattatggca aggatttgaa
    21841 agatttgtcc tatgctcagc tagccttgct ggcagggatt ccacaggccc caagccagta
    21901 tgacccctac acacagcctg agacagctca aagccgccga aatattgtcc ttcagcaaat
    21961 gtatgctgaa aagaacatta ccaaggctga gtacgaagca gctatcgcca cacctatatc
    22021 agaaggccta cagcctctcc agcaacgcgc cagctatcca aaatatatgg ataattactt
    22081 aaaacaggtg atcgagcagg taaaggctga gaccaacaag gatatcttta cctctggtct
    22141 aaaggtttac acaaacatca ttccagaggc tcaaaaaaaa ctttatgaca tttacaattc
    22201 tgaggactat gtgtattacc ctgatgctga ctttcaggtt gcctcaaccg ttattgatgt
    22261 cacaaatgga cacgttatcg cccaattagg aggacgcaat caggatacca acgtttcctt
    22321 tggaaccaat caggctgtct taaccgatcg tgactgggga tccaccatga agccgatcac
    22381 agactatgga cctgccattg agtccggtgc ttacaattct acagctcaaa caactaacga
    22441 ctctgtctac tattggccgg ggacacacac tcagctctat aactgggacc ggagatacta
    22501 tggttggatg accattcaag ctgctctcat gcaatcacga aacgtccctg cagttagggc
    22561 tctagaggcg gcaggtctta gctatgcaca gtccttcctc agtgatctag gcattaatta
    22621 tccagagatg cattattcaa acgccatctc aagtaacaat agcagttctg attcaaaata
    22681 cggtgcaagc agtgaaaaaa tggctgctgc ctatgcagct tttgccaacg gtggactcta
    22741 ttacaagcca caatacgtca ataaaattga attcagcgat gggaccagca aggtcatcga
    22801 aaataagggc aagcgtgcca tgaaagaaac aacagcctat atgatgactg atatgctaaa
    22861 aacggtacta acctacggta caggtactgc tgctgctatc ccaggagttg cacaggctgg
    22921 taaaactggt acctcaaact ataccgatga ggagctggca caaattgttg agacacatgg
    22981 actatctcct gattacgtgg gaacaatggc gccagatgaa aactttgtcg gctacaccaa
    23041 ccgatacgct atggcggttt ggactggtta taaaaaccgt atgacgccaa tttatggcta
    23101 cagcctagaa attgcttctc atgtttatcg caacatgatc agctatctca ccggcggcta
    23161 cagcgacgat tggaccatgc caagtgggct ctatcgtagc ggcggcttcc tctacctaag
    23221 tggtacctat acaaacagta gcgattatac aagctctgtc tacaacaacc tctatggtaa
    23281 taacagctca gcttcaagcc aatcctcaga tgaggataca actgaagaca gccactcaga
    23341 agcaaacgac agcacaacgt catcatcaga gcagcaatca agctccaccg atgataagaa
    23401 aaccaactga taacaaaaaa ctggttcaaa tgttctgaac cagttttttc aattatttgg
    23461 ctaaggcacc catcggatcc caaggggcaa gtacctgtgg ttctgcctca taggctgcta
    23521 attcatcagc tgttagtagg tccttgcgaa caacaatctg gtaagtatac tcgtccatcc
    23581 aagcatcaga agcaacaaag tatcctttgt caccaacctt gtctccccaa gaattttcaa
    23641 ccttccattt gataggctta ccagtatcat ctaaatcaac acctgtcaaa accatagcat
    23701 gtgtcattaa gctttcgctg taatcaaggc gaccagcctt gtcttggctc aactgaatat
    23761 ccatacctgc ctgaaaatca taggtattaa gggctagaat ccccttttga cgatctgata
    23821 cctgaccaac gtctgaacca aaccaaacgg actctccagc ctgcatttgc ttaatagcaa
    23881 gctccttgaa gcgctccata tcaagattaa ggtagcgcac ctcaggactg ccaacaacat
    23941 taccaagcat atcaaccgta taagatttgc cataaggctt atcagctgtt ggggcgttga
    24001 taacagacac ataatcagac agctttagac caacatattt ttcataaaat gcctgtggtg
    24061 tgatgccctt atcagcatga tagtgattat ccttatcacg ataagcaaaa tcaaattgac
    24121 gaggtggcaa accaagattc atggctaaga aattaaagat ttcctgaagt agctcttctt
    24181 ttttagcctg tactgcctga tgatcagcac cagcactgat cacatctcga agaatctgag
    24241 cgtcctgacg caagagctta ttgaggtatt gatttagctc acgactattg cttgatgaca
    24301 cagactctgg gtagactgat tttggcacaa caccgtattt ttcaaacagg gctacaacca
    24361 tgtcccactg accaccgtct tgctgcggaa cgtccaaaag aaacttaacc ctacggctag
    24421 tcaaggcttg atcagcagtt gcaatcacct gttccataaa ccagtttgat ttttcgtatt
    24481 tgtcccagaa aaaggtgtgt gcttgtgaca actcaaaatc ttctaattta aattctgaaa
    24541 taagcttatg gcgaaaggtg tttaaggctg caaacatcca gcaacgacct gaagcctttt
    24601 gattagagac cttatccttt gtcaagtcaa tggaaaagac aaaatcattg tcgatctcac
    24661 tttgtcttgt ctccaaggat ttaagcaagc cattgtgagt gatggcattt tcaagagcta
    24721 aatatttagc attagcttca taattagcat atagctgttc tgtaaatgtc tctgttaata
    24781 ctgacatcat tttcctccaa agataataaa taacaacacc taaaaataaa gttgacagaa
    24841 aaatccataa atactgtcaa tttcattttc aaggattact tctattatag accttatttg
    24901 atattcttca agtaaaaaaa ttaggctaac ttaatttttt aaagctaagc agcagctttc
    24961 caataaccag acaaaaagcc atctcaaaag acgacaaaac ctgctggact ttgagcacct
    25021 aaacatgtca tatgtccacc tcagcatgaa ctcaaagaag ctagctgtgt ctggctatga
    25081 cttcagttta atcattagct tgccttagcc acaaaaagaa tcgtctccac tgtagcaaaa
    25141 gtgcttgata taacaccatc ggctaagtca aggggcccct gatagttaac tgaaacatat
    25201 ggcaaagcta aaaccaaaga cttcttctcc ttaaagcctc tggtttttag ttagctgagc
    25261 attctccttt atcttggctg ctttaagata gggacaaatc aacaactacc ccaatcccat
    25321 ttacaaaaaa gccctaagtc agagccttca tagggctaag ggtgagggaa gctcttaggc
    25381 aacagctact ggatttatgc ctaatagaag ctcctgtccc tcctcaccta tttaaaatag
    25441 cattggttta tctatagcct gtgtaggttt gaggatcact tccaaaagtc atcaaaaata
    25501 gtaattggca gatggcgctt gtgctgccct ttatgccacc agtcttcaat ccttgcctga
    25561 gcttcagcgg aaatcgtatg cccctctaag taatcatcta tctcttgata agtaacacct
    25621 aatgctacct catctgcaag tcctggcttc ttatcctcta gatctgctgt tggcaccttc
    25681 tcatagaggc tggggtcagc ctttagcacc tttaacaagg ccttaccctg ccgcttagtc
    25741 aagcgaaaaa ggggtagaat atccgctccg ccatcaccaa acttagtgaa aaagcccgta
    25801 acattttcgg cggcatgatc tgtcccaatg acagcaccag ctgtttgacc agcgatagca
    25861 tactgactaa tcatacgctg acgtgcctta atgtttccct tattaaagtc agaaatctca
    25921 agccctgccg cctctaaggc tcttagctga ccatcaacag cctctttaat attaaccgtc
    25981 aaggcttgat caggttgaat aaatgctaag gctttttgtg catctgcctc atctgcctga
    26041 acaccatagg gcaagcggac agcgataaat tggtactgct catcacctgt ttcagcgcgc
    26101 agctcttcaa tcgccatctg agctagcttt ccggctaagc tggaatcctg accaccagaa
    26161 atccctaaga cataagtctt taaaaaaggg tgctttaaca aataagcctt taaaaaatca
    26221 accgactggc gaatctcctg cttaggatca attactgctt tgacctcaag ctgacgaatg
    26281 atatcctctt gtaatgtcat atcaaatcac tccttttaca ggcttccttg cggattttgt
    26341 caataagatg catcttattt tgccaaacat caagcgcaag atccacaggg taatgctgcg
    26401 gattcaagac acgcttatat tcgtcccaaa gcttatcaaa ttcctttcta gcataagcct
    26461 tgatgtcttt taagcttggc agctgataaa cgagctttcc tttatcaaaa atatctacta
    26521 gcaaaggaac agcatcaaaa tctctgacgg ttttattaat gtaggtataa gtcgggtgga
    26581 acatgtgaat ttcctctagg tcattgacat taacacctgt aaaggtgatg taatcgcctt
    26641 ctgacttgcc cttttcgcgg ctggtaattc gccaaacctg ctttttacct ggtgttgata
    26701 ccttttctgc attatttgat agcttgatag tatcgcgcat ggtaccatct gcctgctcta
    26761 tcgaaacaat cttataaacc gctcccagag ctggttgatc ataggctgta atcaattttg
    26821 ttccaacacc ccaaacgtca attttagctt tttgcatttt caggttgaga attgtatttt
    26881 catctaaatc attggaagcg taaatcttag cctctgtgaa gccggcagca tccagctgct
    26941 ggcgtaccct tttagatagg taagcaaggt caccagaatc cagacgaaca cccaagaaat
    27001 taatcttatc acctaattcc ttggccacac gaatagctgt tgggacacct accctcaagg
    27061 tatcataggt atcaaccaag aaaatacaat ccttgtgcac actggcatag gccttgaaag
    27121 catcataatc attaccatag gcctgtacca gagcatgtgc atgcgtgcca gacacaggaa
    27181 tgtcaaaacg ctttccggca cgaacgttac tagttgcgtc tgctccgcca ataatggcag
    27241 cacgtgtccc ccaaacagca gcgtccatct cctgagcgcg gcgtgtccca aactctaaaa
    27301 gtggctcatc ttcaataaca gagcgaatac gagctgcctt tgtagcaatc aaggtttgga
    27361 aattcacgat attcaaaaga gctgtttcta ctagctgaca ttgacctaaa ggtccctcaa
    27421 cctgaacaat aggctcattg gcaaagacca agtctccctc ttgtgctgag cgaatcgtta
    27481 gctctaaacg aagctctctg agataggtca aaaaagcagg gctgtagcct agctccttca
    27541 aataagccaa atcggtctca gaaaaggtca attgctcaag gtattctacg attcgttgta
    27601 gaccagcaaa aactgcatag ccattgttaa aaggctctct acgaaaataa acctcaaaga
    27661 cagcattacg attatgaatg ccctgctcaa aataaacctg catcatattt aattgatata
    27721 aatcagtatg aagggttaag ctatcatctc tgtacatata agtaactcct taacataatt
    27781 gttattatta taccatattt ttggcataga cctgtaagat tcaactaaaa tcctctgctc
    27841 aagctttcta aaaaagaagc cttgagctgc tattaagcct gacatatttt ttgccagtac
    27901 cttcctaaaa agtctatagc acaagggctt atggcttttt aacaaaagca gtttcagttg
    27961 atagcattca taaaaaaaga ttgaagaaat tgaccaaaat agcccctttc ttcaatctat
    28021 ttaactcaca ccttagcctt ttaacgcttt tttacacttg agctgactgt agcagccaaa
    28081 gactagaatc caaatgctag caccaattgc cccgatatag gtggacttct gtaaaaacag
    28141 tgaaataaaa acaaaggcaa aaaaggctag ggtcaatggt gttgttagct gataacttgg
    28201 catcaaataa ccatctggca taaagtcact ggactgacga tatttccaat gcgcaagcat
    28261 ggtcaaagca taaatcgcaa tataaacacc agatgatgag gccgtaatca gcgaaaaggc
    28321 atctgcaaca ccgggcagga tattaatcaa ggccgacacc ccaacagcaa cagcagaagc
    28381 aataatagcc ctacttggta ccccttgacg agatagggtg ttaatcctca aggctttagt
    28441 aagagcattt ggggtctcat tagcgatttg atacaaatgc cgacctgtcg aatacagggt
    28501 cgaatttagg gctgatgctg ctgatgttaa gaccacaaaa ttaattaaag cagcagccca
    28561 tttaatccca atcagcttaa agaccatcac aaagggagac tcgtccgtag gcaactgata
    28621 ccaaggcaca atcgccataa tagacaccaa agcaccaacg taaaaaatga caatccgcat
    28681 cggaatctct tggatggcct tgggcaagac ctttctagga tttgcggtct ctgaggttgt
    28741 aataccaaca aattcgatgg cctgataggc aaagaaaacc atctgaaagg ccatgaaaaa
    28801 tttcaacttc ccattcggaa atagtgaaaa atgatccaca atattggcaa ggctggcatg
    28861 accgacatgc gtttcaaagc ccgttagaac cataaaaacg gctgttgcaa tcaaggctaa
    28921 aatcgcaaca atcttaatca tggcaaacca aaattcagtc tctccaaaga cccgcacagc
    28981 aattaaattg atggagctaa gcaacaccaa aaaaacgagc tgaatcagcc aagatggcca
    29041 agcaggaaac caaaactgaa cataggaggc gacagctgta atctctgcca tgccaataaa
    29101 gatcagggaa atccagtaag aaagcccaga aaaatagccc cagcctggcc caatatattt
    29161 tgtaatgaaa ttgataaagg tatgctgatc cggatcatag tatagcatct caccaatagc
    29221 ccgcatcatc aaaaacataa agacacctgt aatcatgtaa acaaagataa tagacggacc
    29281 cgttaaggca atagaacgac cagctcctag aaagagacct gttccaatag tgcctgctat
    29341 cgcaatgagc tgaacatgtc ggttttgcag cccccttacc atgccattct caagttcttt
    29401 agtgctttta gcttcttttg tagacatttg actctccatt caattaaaaa aacaccacta
    29461 ttatatctgt ttttcagaaa atgttcaact ttctctaagg cttgcaaact aaaaaggcca
    29521 accaagcctt tttagcgtta acctttttaa gatgataggc tttcaatgta atggtagacg
    29581 ccttgaccgg caatggcacc atctccaact gctgttgtga tctgacgcag ctgcttttga
    29641 cgaacatcac cgacagcaaa aataccagga atacttgtct tcatttgatc gtctgtcaca
    29701 atccagccct cttgattggt aatgcctagc tcagatacca tttgagtaac cggaatcaag
    29761 ccgacataga taaagacacc accaaagtca tggctagtca cttgacctgt tttgacattt
    29821 tcaatcacaa cattagagac cttaatatcg tttccttgaa tctccttgac aacagaatcc
    29881 cagataaaat caagcttttc gttggcaaaa gcacgctcct gcaagatctt ttgggcacgc
    29941 agctgatcac gacgatgcac aatcgttact ttcttagcga actgggtcag gtagatggct
    30001 tcctcaactg ctgaatctcc tcctcctaca actaataact cctgattgcg aaagaaagca
    30061 ccatcacaga ccgcacaata agaaacacct cgactggtgt actcctcttc tccagcaaca
    30121 cctaaaagac gatgctttgc tcctgtcgcg acaatcactg ttttagtatc gtagtgcgta
    30181 tcttctgtgt acacacgctt ataatcacca caatcctcaa ccctttgaac aatgccataa
    30241 atgttttcaa ccttaaattt ttcaagcggc tcatacatct ttaacgatag ctctggtcct
    30301 gaaatgtgat catagccagg ataattttca atatctgatg tgttattcat ttgaccgcca
    30361 ggtgccccct gctcaataat gccaactcgt aggttactac gtgctgcata taaagcagct
    30421 gtcataccag caggtcctga tccaataatg agtgtatcgt acatgggtta actcctctta
    30481 atagtcttgt catcatttta acaatagcta catcgtattg caattatttc gccttcaata
    30541 ccaccagaat gctcataaag gcaaaggaca aaatcggaat cgtcaaaata gcaaccataa
    30601 tcatctcata taaaaatgcc tgtctctgga gaatggtttt atcctttttg gtcacagcac
    30661 gccataaaat ccacaaaaga caaagcatga ccatcgtaat agctgctaac aacagacctt
    30721 ccaaataaaa gcgaaaaatt tctactaaca tctttatcta cctgattacc ataacctttt
    30781 ttcatggcag cttagctttt aagcacatac aagaaaagcc tagcctacct agaccttttt
    30841 attatatcaa aagccggctt ttaaatatac gtttttgcat agtttgcaaa aaattccttt
    30901 gttcttgctt ccttagggtg tctaaagatc tgctcaggag ctccctcttc aagaattttc
    30961 cccttgtcta aaaaaagcac cctatctgca acctgataaa caaaagccat atcatgactc
    31021 actaaaatca tcgtttgacc tgccttggca gcatcaataa tagaccgttc aacctctcca
    31081 accagctcag gatccaaggc tgaggtaggc tcatctaata atagcacatc tggcttcatg
    31141 gctaaagcac gcgcaatagc aaccctttgc ttttgaccgc cagataaatg acgagggtaa
    31201 tggttttcac gatcagacaa gccaacctta gctaattctg ctctagctat gtctgttgct
    31261 tcttggtcag acagtttttt aactattttt aatccttcct tgacattgtc aagcgctgtg
    31321 cggcgttcaa agaggttaaa ttgctgaaag accatcgcta attttcgtct aagcgttaga
    31381 atgtcttctt ttgtgatgtg ttcaaagtca actgcaaagt catcaatcgt aatacttcct
    31441 gtatctggct gttcaagata attcatgctt ctaaggaagg ttgattttcc tgcacctgat
    31501 gcaccaacca gagctataac ctgccctttt tcaatcgtca ccgttaaatc gtctaagatc
    31561 ttttgtccag agaaggactt ggttaaatga gttaccttaa tcattagcgc aattctccta
    31621 tcttgctatt atttgttggg attggtgctt tgatagccat gttatattca attaggcgac
    31681 cagcctgttc tatcaaaata ctaatgcccc aataaactaa ggcaactgag atgtaacgtt
    31741 caaaataacg ataatctgct ccccctagaa tctgtgcctg tgcaaacatt tcaacgatac
    31801 ctgcattgaa ggccagagag gttccctttg tcaggcctat caacccatta atcaaggtcg
    31861 gtgttgccac aacagcggca tttggaatga taactcggcg ataaacctga gcagaggtca
    31921 ttcctaggct cttagcagcc tcaatttcgc ctgtgtgaac agattgaatc gcagctctaa
    31981 tggtttcact cgtataagca gcttcattga aggcaaaggc ggtaatcgca aagatagaag
    32041 ccggaatagc gttgatattc caatcaaagc catagcgttg atttaagaat ttcagaaaaa
    32101 gaggaatacc atagtagctc agcattagct gaaccaatat gggggttcca cgcaaaaagc
    32161 taacaaaaac cgcttgaatc ggataaagaa tgcgaaccct gttgattttg acaatggcaa
    32221 aaaccaaggc caaaaaaaga cccaaggcag caccagctat cgtcaaacca agtgtgattg
    32281 gcagacgcct gataatatct ggaatggcat caaaaacagc atgccagcta aacagcttcc
    32341 cttctgggat caacgagatg agcttgtcat accaagccca cccacttgtt aaaaacgtag
    32401 atgtcatgta tcgccccttt atactggttt gtctcaatat tttcatttta acattcttga
    32461 gatgtcatgt aaaatagtaa atccgcatga taatgataag aaaagcctat cgcagaggat
    32521 aggactcaaa caaaggaaaa aaactctttg aaataccgtt aacagtagcc tcttggagct
    32581 accaagcttg aacttgagcc gaactctcaa agcctccaag tggctaattc tcaaagaata
    32641 tagccactgg tacaagacta acaatcagct actaggccaa aaaggtcaaa agcttggcta
    32701 gctggcacag ctaactgcct caaaggctag gtcaacgaaa gattgaagcc tgcccagggc
    32761 ttgagggctt ttagccctgt caattaattg accttggaga taaagtctcc tcccaaaaat
    32821 gcttggctga gctttctgag ctgacctgat tttttaagct tagccagcct tttgttgaca
    32881 aagctctgta gagccttacc cttttgatca ttggcaaaca cataatattc caagccatcc
    32941 ttagcagtat cagcctgctc cttgagcttt gtcacatgca catcaaagcc ttgctcctca
    33001 gctacggttg ttagagaaat agcgtcatag aaaagaaagt ccagttgacc attctccagc
    33061 agctgcagcc tttgagtaaa tggggttgac tcagaagcat aggtaaggtg aataggcttt
    33121 tggtcaggat gggattggtt ccatttttca aggataagca tgtaattgga gccagctatt
    33181 ccttgggttt tctttccaga aagatcagct aagcttttat actgctgctt accctttgtt
    33241 gccagagcat aatgcgaggc cgaaataggg cttgaaaaca aatacttttc agctctttcc
    33301 ttactatagc caaaattatt ggccccaatc tgataacgac ctgcatcaat accagccagg
    33361 atcgatggaa aaggaaccac ctctatgctt aaccgatact ttttggagcc tttaaaaacc
    33421 ctttttagaa cctcaatatc atagcctgta acgctatgct tcttcctata ggtaaagggc
    33481 ttagtggcag catctgttgc tactctgatc acctcttttt gacgagctgt gacctcatgg
    33541 ctagtcacga ctgccaagag tcctagactt gctagcaaaa aaaagagtgc tcgctgtaat
    33601 tgttttgtca taccatactc ctatctctta tacagtagcc attttaacaa aaaatgataa
    33661 atttgaataa tatcatttct ctatcaaggc aataagaaaa tagtatcaaa caagcaatta
    33721 aaacagcaca ttcttcattt acctgatcat ggattaacca caacagacaa gctttagcta
    33781 ttagcaggct gcctaagcca aaatcaacac ctcaagcttt caactgactg atgtaaaagc
    33841 tagtagtcac ctctacaaga agaaaaagaa ctgtttgtgt cattcaacca gtagcaccct
    33901 tcttaactgg tcattcctat ccagctctac tactaggctg tcagttaacg atcagaaaaa
    33961 aagttgacct atctgcctta tgaagcctag aaaactagct ttca
//
LOCUS       DARYXS010000010        33017 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.010, whole genome shotgun sequence.
ACCESSION   DARYXS010000010 DARYXS010000000
VERSION     DARYXS010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33017
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.010"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(310..909)
                     /locus_tag="TV193_000390"
     CDS             complement(310..909)
                     /locus_tag="TV193_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1512625.1"
                     /translation="MKRRKARRSHREASSWLAAGIVLGSMLLSLWTLASAKDHLKPHA
                     NSSTMLFVSKISHSAQAVAQRNKLYASVMMAQAILESANGQSKLSQEPYYNFFGIKGS
                     YKGKSVILPTLEDDGQGNLYLIDASFRSYGSLTACFEDYARVLSDPLYRPTHRGIHTS
                     YQQATASLTGTYATDTSYGEKLNRIIGDYQLTYFDAPIR"
     gene            complement(1487..3433)
                     /locus_tag="TV193_000391"
     CDS             complement(1487..3433)
                     /locus_tag="TV193_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1512626.1"
                     /translation="MKIQDLLRKDIMILDLQAVSKEAAIDEMITELVEHGIVHDFDVF
                     KKSILAREEQTSTGLGDGIAMPHSKNVVVDQPAVLFAKSNKGVDYKSLDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADQLRKATSPDEVIAVFDAASDQKEVAFVPT
                     NAQEFIVAVTACTTGIAHTYMAEEALKKQAAQMGVGIKVETNGASGVGNRLTADDIKQ
                     AKGVIIAADKAVEMDRFDGKQLIARPVADGIKKSEELISLILNNAGSVYHAKNGAAEQ
                     AKAAQKTSLGGAFYKHLMSGVSQMLPFVIGGGILIALAFLLDNMLGVPKDQLSNLGSY
                     HEIAAIFKHIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEASLSLAGVPSGFLGALVGGFLAGGVILALRQVLAGLPRSLEGVKSILLYPLLGV
                     LVTGLLMLLINIPMAAINTALNHFLESLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVASGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIIMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGVKLIAPHGGIFVIALTSNPF
                     LYLLFVAIGAVVSGILFGALRKKA"
     gene            complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TV193_000392"
     CDS             complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TV193_000392"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEL1512627.1"
                     /translation="MIYTVTLNPSIDFIVRIDQLDIGAVNRMVSDDTFAGGKGINVSR
                     ILQRLGIDNTATGFLGGFTGRFIKESLAAESINTDFVTVDQDTRINVKIKSAEETEIN
                     GLGPVISKQQLDHLKAILANVSAEDIVVFAGSAPSSLGNDVYKDLIPLVRQAGAQVVC
                     DFEGQTLLDALAYHPLLVKPNNHELEAIFNVSLNGLDDVETYARKVLDMGAQHVIVSM
                     AGDGALLVTQEATYFAKPIKGQVKNSVGAGDSMVAGFTGAFVKSHSPLEALKWGVACG
                     TATAFSDDLAAIDDIKKTYNEVEVEVR"
     gene            complement(4338..5051)
                     /locus_tag="TV193_000393"
     CDS             complement(4338..5051)
                     /locus_tag="TV193_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1512628.1"
                     /translation="MAKITAENYVALEDLMQLLSSSESTVRRDLDELEREGKLHRVHG
                     GAELFHSLQEELSNQEKSVKNSQIKEIIAQKAAELVFDNDVIFIDAGTTTEFLLPFLQ
                     LKKVTVVTNSIHHATRLVDMAIKTIIIGGYVKQTTDASIGHVALEQIRQMNFDKAFLG
                     INGIDEAFLTTPDMEEAVIKKAVIANAKITYVLADATKLGHVSFVKVAPIDRVEIITE
                     KSSTVMLKKIKEKAKVIAL"
     gene            complement(5486..6409)
                     /locus_tag="TV193_000394"
     CDS             complement(5486..6409)
                     /locus_tag="TV193_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEL1512629.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEAHLQAIKENGL
                     KISGDVEETVKLPIMKPTEATKEADLIILFTKAMQLPQMLTDIKGIIGPETKVLCLLN
                     GLGHEDVIRHYIPEHNILMGVTVWTAGLEGPGQVHLQGVGALNLQSMDPANQEAGHQI
                     ADLLNDAQLNATYDDNVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLNMVKEI
                     IHEFVIVGRAEGVELNEEEITAYVMETSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGIDTPYCRLITQLVHAKENILKIK"
     gene            complement(6421..7479)
                     /locus_tag="TV193_000395"
     CDS             complement(6421..7479)
                     /locus_tag="TV193_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEL1512630.1"
                     /translation="MTTTNKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     TVAAEFLHIVQVFQFFTPVMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLKGIGDLINMMITAALAVLAVKWFGDKFGSLTIILLPIIIGTGVGYIGWK
                     LLPYVSYVTTLIGQGINSFTTLQPILMSILIAIAFALLIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTTAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKYPVMAIPMMMTAI
                     VSSLTVPMFNLIGTPASSGFGLVGAVGPIASLAGGSNIVIIIIAWLVIPFGVAFVAHK
                     LCKDILKLYKEDIFVFEG"
     gene            complement(7611..8603)
                     /locus_tag="TV193_000396"
     CDS             complement(7611..8603)
                     /locus_tag="TV193_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1512631.1"
                     /translation="MQEKIYDITIIGGGPVGLFAAFYAGLRGMTVKIIESLSELGGQP
                     AVLYPEKVIYDIPAYPALTGAELTQKLIEQLSRFDDRIAVCLKEEVLSFEKADGNFVI
                     QTSKARHYSKAIIVACGNGAFAPRTLGLDNEQLFADHNLFYNVHSLNQFAGKRVVICG
                     GGDSAVDWALALDGLAKSVTLVHRRDAFRAHEHSVELLKNSHVTTLTPFVPLALEGEN
                     GFVNKMTIQKVKSEEEITLELDSLIVSFGFSTSNKNLKHWNLDYKRSSLLVSPLFQTS
                     QEGIFAIGDAAAYEGRVDLIATGFGEAPIAVNQAIKYIYPDRDNRPVHSTALID"
     gene            complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TV193_000397"
     CDS             complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TV193_000397"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEL1512632.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASH
                     QEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLL
                     ETYDFSDEEKRIFDKIKSGLSEGEN"
     gene            complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TV193_000398"
     CDS             complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TV193_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEL1512633.1"
                     /translation="MEYFSVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDK
                     DRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGYSLKIAKENQGKLAEGEFYYH
                     QIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLCVDIEKHRV
                     DVEIMEGLDDED"
     gene            complement(10613..10951)
                     /locus_tag="TV193_000399"
                     /pseudo
     CDS             complement(10613..10951)
                     /locus_tag="TV193_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677858.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11117..11356)
                     /locus_tag="TV193_000400"
     CDS             complement(11117..11356)
                     /locus_tag="TV193_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEL1512634.1"
                     /translation="MDTIENLIIAIVKPLISQPDKLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TV193_000401"
     CDS             complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TV193_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEL1512635.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK"
     gene            complement(12069..12686)
                     /locus_tag="TV193_000402"
     CDS             complement(12069..12686)
                     /locus_tag="TV193_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1512636.1"
                     /translation="MSSFGVSHSLLKKLFKILGGLSILFSVMLVVYLIRQLDIINNPK
                     ALAHLIKDHLLIGAICFFILQIVQVVVPIIPGGVTTVVGFLAFGPILGFMLNVFGICI
                     GSSILFQLVRRYGKPFILLFLSMEQLQFYEKKLSTKLFERFFILNMISPLAPADALIM
                     ITGLSQMTYKRFLLIILICRPISILTFSYFWIYGGEFLKHILMHY"
     gene            complement(12679..13902)
                     /locus_tag="TV193_000403"
     CDS             complement(12679..13902)
                     /locus_tag="TV193_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1512637.1"
                     /translation="MENWKFALSSIWGHKLRSILTMLGIIIGVAAVVIIMGLGAAMTK
                     RVTDSFSNDQKEVQLYFKAKGDEDNPYAAFAAHENEQEVKPEWLEQIVKAIDGVDSYY
                     YTNNSTSTISFEKKKMDNVAITGVSQDYFKVKKYDIVAGRTLNSKDYKNFSRIILLDT
                     VLADELFGKGNYEQALNKVVSLDSKDYLVVGVYKTDQEVVSFAGGISGGAIMANTQVA
                     SEFHVKEIGSVYLYIGDVKRSLELGNQAAAMLTTLSHVKEGEYAVPDNSQIINDINAQ
                     FSIMTTVVGSIAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIE
                     SVVLTLIGGLLGLLLAQMCVGVLGNAMQLKGAAVSLDVAAVAIIFSASIGIIFGLLPA
                     NKASKLDPIEALRYE"
     gene            complement(13914..14624)
                     /locus_tag="TV193_000404"
     CDS             complement(13914..14624)
                     /locus_tag="TV193_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512638.1"
                     /translation="MPDEKKELIQLKSIVKSYQNGDQELQVLKGVDLTVYEGEFVAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYRLNGTQVEILNDRKLAQVRNEEIGFVFQQFFLL
                     AKLNALQNVELPLIYAGVGVSKRRELAKQFLEKVELGMRMKHLPSELSGGQKQRVAIA
                     RALVNNPSIILADEPTGALDTKTGEQIMRLLTELNKEGKTIIMVTHEPEIADFATRKI
                     VIRDGEITADTTESVRID"
     gene            complement(14624..15886)
                     /locus_tag="TV193_000405"
     CDS             complement(14624..15886)
                     /locus_tag="TV193_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEL1512639.1"
                     /translation="MSKRGKIKLSTKTKGIIAGAVALTVVVIGGVLWKQQQDTISDQN
                     IKLPYSAVNVTEGTIASSTLLSGTVKALSEEYVYFDASKGSDATVTVKVGDQVTQGQQ
                     LVQYNTTVPQAAYDTAVRNLNKIGRQINHLKTYGVPAATTETSKDEETGQETTTTIQP
                     SAQQNASYAQQLQDLNDSYADAQAEVNKAQQALNETVVVSGVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGKLQVKGTLTEYDLANIKVGQAVKIKSKVYADQEWTGKISYVSNYPT
                     DANAGGSTAGGSGSSSSTGATYDYKIDITSPLNQLKQGFTVSVEVINEAKHALVPVTA
                     IVNKGKKHFVWVYDDSTAKAKKVEVTLGNADAERQEVSAGLKVGDIVIANPDKNIKEG
                     EKLEDVISADTKASKDSKKSSKESEVIK"
     gene            complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TV193_000406"
     CDS             complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TV193_000406"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEL1512640.1"
                     /translation="MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQV
                     VLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     SKAGILQELGVELLGTTLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEAAIGFAN
                     AIGYPVIVRPAFTLGGTGGGICSNEEVLRDIVENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALK
                     IEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDM
                     LNPVTGTTYAMFEPALDYVVAKLPRFPFDKFERGERRLGTQMKATGEVMAIGRRIEEC
                     LLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAG
                     LTKIDLFFLDKLRHIVELEQDLIKKPVDIDLLIEAKRYGFSDQKIAELWQTDAASIRR
                     LRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIEL
                     EQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDCAEDRELFEKALKELGIPQP
                     PGKTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENENDLRSYMKTAVKASPEH
                     PVLIDSYILGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQD
                     KIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSD
                     LTLEKALYKAFEASYLHMPEYGTIVFTIADDHKSEALILARRFSAIGYQIMATEGTAA
                     FFADQGLDSQLVGKIGDNAHDIPALLRKGQIQAIINTVGTKRVTDKDGQMIRSSAIEQ
                     GVPLFTALDTAVAMLRVLESRTFSIEAI"
     gene            complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TV193_000407"
     CDS             complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TV193_000407"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEL1512641.1"
                     /translation="MAKRLLILEDGTIFEGKPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQLLVFTYPLVGNYGINRDDYESIAPTCKGVIVSEVSRIASNWRQQMTLDEFLK
                     HKGIPGISGIDTRALTKIIRQHGTMKATMADDGDTLEHLKDQLRATVLPTNGIEQVST
                     KTAYPAPGVGKNIVLVDFGLKHSILRELSKRQCQMTIVPFDITAEEILQLNPDGLMLS
                     NGPGNPEDLPEALEMIRGVQGKIPIFGICMGHQLLSLANGAKTFKMPFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERDSLPDCLMVTHEEINDKTVEGVRHRHVPAFSVQFHPDA
                     APGPHDASYLFDEFLDMIDAWQLEQQGKC"
     gene            complement(20909..21844)
                     /locus_tag="TV193_000408"
     CDS             complement(20909..21844)
                     /locus_tag="TV193_000408"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEL1512642.1"
                     /translation="MSVVNNRVALKHLVSMEHLTNEEVLGLISRGSEYKAGKVAIKDN
                     SRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALG
                     TEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGRYMAIDHIIDQLD
                     VLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRRLKDSAIIMHPAPVNRDVEIADH
                     LVEAPKARIVAQMANGVFVRMAIIEAILNGRNDKV"
     gene            complement(21902..23161)
                     /locus_tag="TV193_000409"
     CDS             complement(21902..23161)
                     /locus_tag="TV193_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEL1512643.1"
                     /translation="MKDVIYDVEEVPKAGILLGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTTFKIPAYMGSSFAYIAAMQMLMKTDGIGAVAQGAITGGLVY
                     LVVALVVKAIGNEWIDKILPPVVVGPIVMVIGLSLASTAVSDVMLKDGKYNLLYLLIG
                     LVTLLAIIFFNIYGKGIVAIIPILLGLLVGYLFAILVGMVTGQSIVDFTQVAKAQWLS
                     VPAVAIPFLTYDITLYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGLAQVIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAGLLSFVGKVSA
                     LIQSIPTPVIGGISIALFGVIASSGLKILIEAKVDMDNKKNLLIASVILVSGIGGLML
                     QINGLQISGVAFSTLLGIILYQLLPEN"
     gene            complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TV193_000410"
     CDS             complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TV193_000410"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEL1512644.1"
                     /translation="MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVY
                     LARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYT
                     GRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVE
                     VDGQDRISIVDPG"
     gene            24060..24674
                     /locus_tag="TV193_000411"
     CDS             24060..24674
                     /locus_tag="TV193_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1512645.1"
                     /translation="MNDITRKINHKQLIQITTILGIIVTIVILFYLQQHPNLFAVGGP
                     FQTYLMELGILAPCLFILLQIIQVVYPIIPGGLTCVLGHVVFGPFWGFLYNTLGIFIG
                     SLLSFMLARKYGEQFAKAFVSDDTYNKYIPYLNKGKYFERFLITAFILPGFPDDFLCM
                     VAGLSSMSIKTFTSIFLISKPITLYIYTLLAYQGIQIVGQVLQS"
     gene            complement(24755..25645)
                     /locus_tag="TV193_000412"
     CDS             complement(24755..25645)
                     /locus_tag="TV193_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1512646.1"
                     /translation="MEIKITESGHRLDKALADLTPLSRSQANDQIKQKRVLVNGLPKK
                     AKYIVQVGDCISYHIPEESSLDYQAQDIPLDIVYQDDVLAIINKPQGMVVHPSAGHST
                     GTLVNALLYHIKDLSSINGVIRPGIVHRIDKDTSGLLMVAKTDKAHQLLADELKAKKS
                     LRKYVAIVHGNLPKDRGVIEAPIGRSEKDRKKQTVTAKGKEALTLFKVLERFGHYTFV
                     ELQLETGRTHQIRVHMAYIGHPLAGDPLYGPRKTLAGKGQFLHAQTLGLTHPVTGEEL
                     VFTVEPPEIFQRTLEQLRQG"
     gene            complement(25635..26093)
                     /locus_tag="TV193_000413"
     CDS             complement(25635..26093)
                     /locus_tag="TV193_000413"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1512647.1"
                     /translation="MKRISFIMAAIVLMILDQLSKWWTVTHIELGQVKPFIPGLVSLT
                     YLQNRGAAFSILQNQQWFFTIITVLVVGYAIYYVLKHPKASFWLQLSLLLIISGGLGN
                     FIDRLRLSYVVDMIHLDVINFAIFNVADSYLTIGVLLLVICLWKEEDYGN"
     gene            complement(26321..27250)
                     /locus_tag="TV193_000414"
     CDS             complement(26321..27250)
                     /locus_tag="TV193_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1512648.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSVKDLETELG
                     FQIFRRTTAGTVLTSQGLLFYEKALEVVKCFDSLEKEFSQSALEPNEFSIASQHYDFL
                     PALITAFSQKHAGHKVFRVFESTTMQILDEVAQGNSELGIIYLNAQNRQGLFQRMDKL
                     ALDYVELLSFTTHIYLSKNHPLAQRKALFLEDLQGLPAVRFTQEKEEYLYYSENFIDT
                     SKSPHIYTVSDRATLNGILERTAAFATGSGFLDQQSVNGIKVIPLRDHMEHKMIYVKR
                     RDKNLSAAALHFVTILQDYFEHRKEKQAIDNGT"
     gene            complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TV193_000415"
     CDS             complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TV193_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEL1512649.1"
                     /translation="MIKLNLSNLQHFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(27972..28304)
                     /locus_tag="TV193_000416"
     CDS             complement(27972..28304)
                     /locus_tag="TV193_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEL1512650.1"
                     /translation="MIKVRLTKDAAGWTEMLITGHAGSGEYGFDVVCASVSVLAFNLV
                     NSVEQMTGLEPALEMVDGGGFLRVTKPEGFTEQQEQVWQILFESVVIGLENLAEHLSE
                     YVQKPVMN"
     gene            complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TV193_000417"
     CDS             complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TV193_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEL1512651.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     KA"
     misc_feature    complement(28665..28739)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(28861..30054)
                     /locus_tag="TV193_000418"
     CDS             complement(28861..30054)
                     /locus_tag="TV193_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEL1512652.1"
                     /translation="MLKDFQYKKTMLSVLTLIVVILVFGLAFDLLGMSKKGTQTKSKT
                     PQKTQTARVVANGDILIHDILYMSAKKADGSYDFNPYFEYVKDWISQADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEAIAAALKHTGYDVVDLAHNHILDSRLEGALNTKRVFADMGI
                     DSIGIYEQDRSKENILIKKVNGIKIAILGYSYGYNGMEATLSQEEYDKHLSDLNEEKI
                     QKDILRAEKEADITIVMPQMGTEYALEPTAEQKTLYRKMIDWGADVVLGGHPHVVEPA
                     ETIVKDKEKKFIIYSMGNFISNQRLETVDDIWTERGVLMDLTFEKKGQKTKIKTVKAH
                     PTMVLAKPKGLYGSEGYELYSYRTMVLEDFIKGGRYYDKIDPETQEKAAIAYKEMNAL
                     VNLKW"
     gene            30319..30936
                     /locus_tag="TV193_000419"
     CDS             30319..30936
                     /locus_tag="TV193_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEL1512653.1"
                     /translation="MKHNSFSRSLLLPLLICSLSACSSHTEKKDHTKDATAITDTRKA
                     EHQDIRANMEKVKLATASTDFKGGSSLEELITIFGQPSQHEEKAAGSVTLDSYTWQFD
                     HVTVNINLYENSSIVKTIANFAFIRDLTLSLKDYNSLKKGMTYDEVKQLLTEPDNYSQ
                     ANSSEKETIQAIWISGLKAQTQGANIALTFENNQLTEMSQVGLED"
     gene            complement(31234..32463)
                     /locus_tag="TV193_000420"
     CDS             complement(31234..32463)
                     /locus_tag="TV193_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1512654.1"
                     /translation="MRGLIKNVVFRTLTVSNFLSALGSYIYNIVFIIYATTLPYSHIA
                     VFIANIITIIPMVFTFWIGVKADKTKRKTRNLIVIGFIQSLLFTLVALLMTNQTFLVF
                     AFVGFLNVVSDILSDYKNGLRLPIMQKNIESEKLYEAYSFAQFIGYLSSIAGQALGVW
                     LLTTSGNNYAFVALINAISFLLSSVVLLKNRQKLRHDVVEASEAGVSLMKQFKVMYTR
                     MTETFKKIDHISFVMLLLSILTLNAIGGAINSIYHFYLMDHQLFHFHYGQSLVIVDAV
                     TIIGAMLGNLTPKDYFSRLSISKLVQTQGIAFLLVGVSNALQLPAIIGVLCLAFAAYI
                     MGKATPKLDALLMENLPSDMLAQSNNFLGLLFSLSLPVGVFIFSFLALYNMTLCWILF
                     MVLSLAALALSTSSTRG"
     gene            complement(32498..32986)
                     /locus_tag="TV193_000421"
     CDS             complement(32498..32986)
                     /locus_tag="TV193_000421"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512655.1"
                     /translation="MQLKSEVNLGLNGLAGVLFYLSSISYDNEIIEKGIDFILESLVE
                     DSDGNRGVLISENSVSPYLSNGTAGIVQLLIYVNSDKYIKDIKNLSESLLVEFAQFSG
                     LWNGMLGIAMTLLQVFRLTNDTLYLEKACELLISSKIMSEHHIKLQYEFRYAVSIFNQ
                     VK"
BASE COUNT         9972 a         7663 c         5874 g         9508 t
ORIGIN      
        1 aatcaaaaga agatagcatt tctgctatct cactgttagc cactacttac aggtaaaaat
       61 acaccttgtc tatttgtagt ttaactatcc atttaatcca tcaataagcc aaaccagacc
      121 gtttaatcat ctacccagcc ttacacatag tattttctca catcatttgt agaattgctt
      181 tctccttgca tgtcaccatc tcgtcttaaa cgttcgtaaa gggctgtttg atcttttcta
      241 actattttag aaaattattt tgctgttctg atgaggttaa tctcgttaga tcagtcatgc
      301 tggaggtagc taccgtatgg gagcgtcaaa ataagtcagc tgataatccc ctataatacg
      361 attgagcttt tcgccatagc tagtatctgt ggcatatgtg cctgttaaac tagcggtggc
      421 ctgctgataa cttgtatgaa tacctcggtg agtagggcga taaagcgggt cactcaaaac
      481 cctagcataa tcctcaaagc aggctgttaa gctgccatag gaccgaaaag aagcgtcaat
      541 tagataaagg ttgccttggc catcatcttc caaggtaggt aaaataactg attttccttt
      601 atagcttcct ttgataccaa aaaaattata atagggctct tgacttagct tagattgacc
      661 atttgctgac tccaaaatag cctgtgccat catgactgag gcatagagct tgtttcgctg
      721 cgcaactgcc tgagcggaat gactaatctt gctcacaaat agcatggttg agctattggc
      781 atgaggctta aggtgatcct tagctgacgc taaggtccaa aggctaagca acatgctgcc
      841 taaaacaata ccagcagcca gccaagagct agcttccctg tggcttcttc tagctttcct
      901 cctcttcaac agaaatatcc tcacttcctt gcttttaaac ctagtatagc aaaaattaaa
      961 agcaaaatgt agccagacca catgctcacc tcaaaaacag gccttatgac ttctaaaaag
     1021 acctagcagc cacaacaggc gcataaaaag tttttaacaa gaaaagaaga ctttgctgta
     1081 tttcaatcca cgctcctgca aagggagcga tacaaaaaat aaatggaata tctacaatca
     1141 aatgatttca atgtttagct atttcaagaa tatatcttat ttttgataga tgttactata
     1201 ggaaaaacgt tgatagtatc tactttaatt gatactataa ttcgaaaata actgtttcgc
     1261 acgtttggtg tggcttagtt tagcagggct attgggtcac tgcttagcta ttctagatca
     1321 gattgattct ctctaaatat tagcttttcg ccagtcatca ctactagcaa caaacaaaac
     1381 gcacgacatc atgtaaaaac aggctgatgt catgcgtctg atgttttatt aagactaggt
     1441 ctaattcaga agctttccct agtacttgtg gctttatagc cagtaactaa gcttttttac
     1501 gaagtgcgcc aaagagaata ccagaaacca ctgctccaat agcgacaaac aataggtata
     1561 agaaaggatt gcttgtcaaa gcgataacga agataccgcc atgtggtgcg attaatttga
     1621 cacctgctag accaacaaga gcacctgtta gggcagagcc agcgataaag cttgggatag
     1681 cgcgtgctgg gtctgctgca ccaaacggaa tggctccttc tgtaatgaag gaaagtccca
     1741 taataatgtt ggtcaagcca gattcacgct cttccttggt aaatttgtct ttaaataaga
     1801 gtgttgccac aaaaacagct agaggaggca ccataccacc tgccatgaca gcagccataa
     1861 caactgaccc accgcttgca acggttgcag caagtgttcc tgtaccaaag acataggctg
     1921 ccttattcac tggaccaccc atatcaacag ccatcatgcc gccaacaaga agtcccataa
     1981 gaactgcaga gctacctgac agactttcta agaagtggtt caatgctgta ttgatagctg
     2041 ccataggaat attgatcagc agcatcaaaa gacctgtcac aagaacacca agtaatgggt
     2101 aaagaaggat tgacttgacc ccttcaagcg aacgcggaag ccctgcaagc acttgacgaa
     2161 gagcaagaat tactccccct gcaaggaagc cacctacaag cgcaccaaga aatccagacg
     2221 gtactcccgc taatgatagg ctagcctcac cgccagcagc aaatggaacc tttccaaaag
     2281 caagaccgct agaagcaatg gcacctgcca caaagcctgc cacaagacct ggcttttcag
     2341 cgatagaata agcaatgtag cctgctagca ctggcaacat gaatgaaaag gccgcaccac
     2401 caatatgttt aaagatagct gctatttcat ggtaggatcc caaattagac agctgatcct
     2461 ttggtacccc aagcatgttg tcaagcaaga aggcaagagc aattaggatt ccaccaccaa
     2521 ttacaaatgg cagcatttgt gatacaccac tcatcaggtg cttgtagaag gctccgccta
     2581 ggcttgtctt ttgagctgct tttgcttgtt cagcagcgcc attcttggca tgataaacac
     2641 taccagcatt gtttaaaatc agtgaaatca attcctcgct tttcttaata ccatctgcta
     2701 caggacgagc aatcaattgc ttaccatcaa agcgatccat ctcaaccgcc ttatcagcag
     2761 cgataatcac tcccttggcc tgcttgatgt catcagctgt caggcgattg ccaacccctg
     2821 aagcaccgtt ggtttcaacc ttgatgccga cacccatctg tgcagcctgc tttttcaagg
     2881 cctcttctgc catataagta tgtgcaatac ctgtcgtaca agctgtcaca gcaacgataa
     2941 actcctgagc atttgtagga acaaaagcta cctctttctg atcagaagcc gcatcaaaga
     3001 cagcaatcac ttcgtctgga cttgttgcct ttcgcagttg atctgcaaag ccatccttta
     3061 ataggtattg ggataattcg gctaaggccg ctaagtgagt atcatttgcc ccttgaggtg
     3121 ctgcaatcat aaagaacaga tcagttggct gaccgtctaa ggatttgtaa tcaacgccct
     3181 tgttagattt tgcaaagagc actgctggct ggtcaacaac aacatttttt gaatgcggca
     3241 tagcaatgcc atcgccaaga cctgttgagg tttgctcctc gcgagctaag atactctttt
     3301 taaacacatc aaagtcatgt acaatcccat gctctactag ttctgtaatc atttcatcaa
     3361 ttgcagcctc ttttgaaaca gcctgcaaat caagaatcat gatgtctttt cttaataaat
     3421 cctgtatttt catcgaacct ctacctcaac ctcattatat gtttttttaa tatcatcaat
     3481 tgctgctaaa tcatctgaaa aagcagttgc tgttccgcag gccactcccc attttagagc
     3541 ctctagcgga ctatgacttt tgacaaaggc acctgtaaag cctgccacca tcgaatcacc
     3601 agctccaaca gaattcttca cctgcccttt aataggctta gcaaaataag ttgcttcctg
     3661 agtgaccagc aaggcaccat caccagccat cgaaacgata acatgctgcg ctcccatgtc
     3721 aaggacctta cgagcatatg tttcaacgtc atctagccca tttaagctga cgttaaaaat
     3781 agcttctagc tcatggttat taggctttac gagcaatggg tgatacgcca atgcatctag
     3841 caaggtctgt ccttcaaaat cacagaccac ctgtgcccca gcttgtctga ccaatgggat
     3901 caagtcctta tagacatcat tgcctagact tgaaggcgct gagcctgcaa aaacaacaat
     3961 gtcctctgct gacacatttg ccaatatagc ctttaaatga tccaattgct gctttgaaat
     4021 cactggtcca aggccattaa tctctgtctc ctctgctgat ttgatcttaa cattgatccg
     4081 cgtatcctga tcaaccgtta caaagtcagt attgatgctc tcagcagcta gactttcctt
     4141 aataaaacgc ccagtgaagc cgcctaaaaa gccagtcgct gtattatcaa tgcctaatcg
     4201 ctgtagaatg cgactaacat taatcccctt tcctcctgca aatgtatcgt cactgaccat
     4261 gcggttaacc gctccaatat ctaattggtc tattctgaca ataaagtcta tagaaggatt
     4321 taaggttact gtgtaaatca tagtgcaatt accttcgctt tttccttgat tttcttcagc
     4381 attactgtcg aagatttctc tgtaatgatt tcaaccctat caattggagc aaccttgaca
     4441 aaggaaacat gaccaagctt tgttgcatca gctaatacat aggtgatttt agcattggca
     4501 atgacagctt ttttaataac agcctcctcc atatccggag tggttaaaaa tgcctcatcg
     4561 ataccattga taccaagaaa agccttatca aaattcattt gcctaatttg ctccaaggca
     4621 acatgaccga tgcttgcgtc tgttgtctgc ttgacatagc caccaataat aatggtcttg
     4681 atcgccatat caaccagtct agtcgcatga tgaatagaat tagtcactac tgttactttt
     4741 tttaattgca aaaaaggaag gagaaattcg gttgttgtcc cagcatcaat aaagatgaca
     4801 tcattatcaa aaaccagctc tgctgccttt tgagcgatga tttcttttat ttgactgttt
     4861 ttgacagatt tttcctgatt agataattcc tcttgtaagg aatgaaaaag ctcggcacct
     4921 ccatgcactc gatgaagctt gccctcacgc tccagctcat ctaaatctct acgaacagtt
     4981 gattctgacg agcttaacag ctgcattaaa tcctctagcg caacgtaatt ctcagctgtg
     5041 atttttgcca taatgagctg ttttcgtttt gattttaaga taaaaccacc cctttgtctg
     5101 aaatcgttta cagctctatt atactacact ttattccaaa gtcaagcact atctttcaaa
     5161 aacattcaaa ttcaatctta gacctctatt gccttaacaa taactgccaa ttgatcagtc
     5221 attgtccccg tcaatacctg tagactaatg attaacgact tttttattaa ctagagccca
     5281 aaaagcgctc acctgttgca aaagtctgaa acacaatagt ctcttacaaa tcaaaaagca
     5341 acggatttac tgtcgttgct tcataatgag agtctaggac aaagtctttt cagccaacaa
     5401 gacaaaacga gagagtcacc tattgtgagc ctctcgtttt attgtactga gaaattgttt
     5461 tatcccagac tccttatgtc taaacctatt tgatcttcaa aatattctct ttggcatgga
     5521 ctagctgtgt aatcaagcgg caataagggg tatcgatacc aagcttttca cccttggtat
     5581 ttaccgcacc gttgataaag tcaatttcag tcaagcggtg attttgaaca agatcctgat
     5641 gcattgatgg gtagtgatga gcagccttca ctgaggtttc catcacatag gctgtgattt
     5701 cctcttcatt aagctccacc ccctcagcac gaccaacaat aacaaactca tgaatgattt
     5761 ctttaaccat gtttaaacca tcttcgctgg caaataactc accaatcgtg caatcaagta
     5821 gggcacaggt tgagttcatt gtaccattga cacaggcttt tctccaaata tttggaacaa
     5881 cattatcatc ataagttgca ttcaattgag cgtcatttag caagtcagca atctgatgtc
     5941 ctgcctcttg gtttgctgga tccatgcttt gtagattaag cgcaccaact ccttgtaagt
     6001 gtacctgacc aggtccctca agacccgctg tccaaacggt aacacccatt aaaatattat
     6061 gctctggaat atagtgacga atcacatctt cgtgtccaag accatttaat aggcaaagta
     6121 ccttggtttc agggccaata atacctttaa tatcagtcag catttgtggc agctgcatgg
     6181 ctttggtaaa caaaatgata aggtcagctt ccttagtagc ctctgtcggc ttcatgatag
     6241 gaagctttac ggtttcctct acatcgcctg aaatcttcaa gccattctct ttgatcgctt
     6301 gaagatgtgc ttcccaatta tccagtaaaa taacgtcatt gtttgttttt gaaatttggt
     6361 aaccaaatcg acagcccata gctcctgagc ctgcaatata aactaacatg ctttttcctc
     6421 ttatccttca aatacaaaaa tatcttcttt ataaagcttt aaaatatcct tacaaagctt
     6481 atgtgccaca aaagcaactc caaatggaat gaccaaccaa gcaatgataa tgatcacaat
     6541 attgctgcca ccggcaagtg aagcaatagg accaactgca ccaacaagac caaagccaga
     6601 tgaggctggt gttccaatca gattaaacat tggaacggtt aaagagctaa caatagctgt
     6661 catcatcatt ggaatagcca taactgggta ttttaagaag tttggcatca tcattttcat
     6721 agcgccaagg gcaatggcaa ttggaacacc tgatttgtta acctttaacg ttgcccacac
     6781 aagaacagcg gttgttgaag caatacccat tgaggccgca ccagctgcca taccatttaa
     6841 gccgatagct aaaccaatcg caaccgttga gatcggactc acaatcaaaa gagcaaaggc
     6901 aatggcaatc aaaatagaca tcagaattgg ctgaagcgtt gtaaatgaat taatgccttg
     6961 gccaatcagg gtcgtcacat aagaaacgta aggaagcagc ttccagccaa tgtaacccac
     7021 acctgttcca ataataattg gcaacaaaat aatggttaga gacccaaatt tatcaccaaa
     7081 ccacttcact gctaaaacgg caagcgcagc tgtgatcatc atattaatca gatcaccaat
     7141 gccctttagc tggaaggtcc cagtggcaac acctttttgg ataacctctg tataagccca
     7201 agctccagaa ccgatataag ctgccccgcc gacagccagc tgctgcattg ggttaaattt
     7261 gaactgctgt ccaatcaaaa aaccagccat aactggcgta aagaattgga aaacctggac
     7321 gatatgtaaa aattcagctg ctacagtatt tggcaaaagc ggctttaaaa acgtcgctaa
     7381 aatagcattc ggaataagtg caactacaat cgcaattgct gtaccagcta agaccttatt
     7441 cataaacgag ctaaaggtct ctttatttgt tgttgtcatt tcatgacctc tcttaatatt
     7501 atagtgtgaa aaacatcacg aaagtattct aacataaaaa gagcattttg tcacagctat
     7561 tttaattttt atcaatacgt acagaatatt caattaaatg tcatataata ttaatcaatc
     7621 aaggctgttg aatgaacagg tctattatct ctatcaggat aaatatactt aatcgcttgg
     7681 ttgacagcaa tcggtgcctc accaaagcca gtggcaatca aatcaaccct gccttcataa
     7741 gctgctgcgt caccgatcgc aaaaatccct tcctgacttg tttgaaagag gggagagaca
     7801 agaagacttg agcgcttata atctagattc caatgcttta ggtttttatt agatgtagaa
     7861 aagccaaagc taacaatcag gctgtctagc tcaagcgtta tctcctcttc tgactttacc
     7921 ttttgaatag tcattttgtt gacaaagcca ttttctcctt cgagggcaag gggaacaaag
     7981 ggggtaaggg tagtaacatg agagtttttt aacaattcta cgctatgctc atgagcccta
     8041 aaggcgtctc gccggtgcac aagggtaaca ctcttagcga ggccatctaa ggctaaagcc
     8101 cagtccacag cagaatctcc accaccgcag atcacaaccc tcttaccagc aaactgattc
     8161 aagctgtgaa cattataaaa gagattatga tcagcaaata actgctcatt gtctaagccc
     8221 aaggttctag gcgcaaaggc tccattgcca caagcaacaa taatggcctt agaataatgt
     8281 ctggccttgc ttgtttgaat aacaaagttc ccatcagcct tctcaaaaga caggacctct
     8341 tctttcaggc atactgctat gcgatcgtca aatctgctta gctgctcaat aagcttttgt
     8401 gttagttccg ctccagtcag ggccggataa gctggaatat catagataac cttttcagga
     8461 taaagaacag ccggctgtcc tcctagctct gacaggcttt caataatctt aaccgtcatg
     8521 ccgcgcaggc ctgcataaaa ggctgcaaat aagcctaccg gacctccacc aatgatggta
     8581 atgtcatata ttttttcttg cactagttct ctccttcact tagccccgat ttgattttat
     8641 caaaaatcct tttttcctca tcagaaaaat cataagtctc taataaatct ggtcttctca
     8701 aataggtctt ctttaggctt tgctccatac gccagagacg aatatgctca tgatggccac
     8761 tcattaggac atcaggcacc ttcatgccac gataatcata tggccttgta tactgtgggt
     8821 actccaagag cccagatgag aaggaatcct cttgatgact ggcttgcttt ccaagcacat
     8881 taggaatcag tctcactgtt gcatcaatca ttgtcatagc agccagctca ccaccagtta
     8941 agacaaaatc tcccagagat atttcatcgg taacaagtgt cttaatgcgt tcgtcatagc
     9001 cttcgtaatg cccacaaata aaaattaact cttcctcaag agctaattct tcagcataag
     9061 actgatgaaa gggttttcca gcaggatcca gtaaaatcac tcgaggcttt gtagcctgaa
     9121 tgctatccat ggtatcaaaa ataggctgcg ctctcagcag catgccctgc ccaccaccat
     9181 atggctcatc atcaacatgc ctagctttct ccgcatggtc acgaaaattg tggtaatgaa
     9241 tatctaaaag ccccttttcc ttagcctttc caacaatgga gtgctccaaa ggagcaaaca
     9301 tttccgggaa aagggttaaa atatcaatct tcatcatcta agccttccat aatttcaacg
     9361 tctacccgat gcttttcgat atcaacacaa agaacaaccg atgggatata aggaagcaac
     9421 aggtcacgct tgctttgccg tttgaccacc caaacatcat ttgcaccagg ctgtaaaatt
     9481 tccttaatct ctcctactag ctggtccttt tcatacacct ccagaccaat aatctggtga
     9541 tagtaaaatt ctccctcagc tagcttaccc tgattctctt tagcaatctt aagactgtag
     9601 cccttaaatt gctcaatagc attgatgtga tacattccct taaacttgat aatgtcaaac
     9661 tgcttatgct tgcgatgact cgcaatctca acctcctgca caaaacgatc cttgtcgtca
     9721 aacagggcta gtctagcacc tttttgaaat cgttcctcag taaagtcact cacagacagc
     9781 acgcgcattt ctccttgcaa gccttgagta ttgacaatct tcccaacgct aaaatattcc
     9841 atccttactc ctaatcatct tagactctat agcttgatag acctctattt tttcatgaca
     9901 acacgacatg agtatcatca tcctaagcac tctagcctat cgttaaagct ccccttattg
     9961 taacatgttc tgccttattt tgcacttctc tttcaaaaaa ttaatctccc agttatagca
    10021 gctaagccta gcaagcaaag cccttgatgc taaagaatcc tgatccccct ataattaaca
    10081 aatcatcatg acttgccttg cccaagctca gtcaagtgaa tgaaaaatct gctaaacaat
    10141 agccttgcgc ctcgctgaca agcatcaaaa aaacactcct gctggcaatc tgaactgccc
    10201 cccaattgtt agattttatg tccaactttt gggggtcagt acaatctagt aaactagaat
    10261 caggagtgtt tcattatagc ccaacaagca aaaggaatac ttggtaaaag caaagctgac
    10321 ttgcattgag aagattaaaa ccattcaatc tgtcacaata attatggaaa cattgggaat
    10381 ttaaaaacaa gtatcagctg ctatcaacct gtggggaaat agtctaccta tgcctatcgg
    10441 gccatccatc ataggtcctc tcaagaaatg atgagagcct catcaaccag ctatcatcgc
    10501 cttaaaggag aatgacgaat gttatcgtag gtgtcccaag aaatactaca aaagaaactc
    10561 attttgatct taatgctcta aagggcttga ccttacgtca actgataaag ctctacttca
    10621 tagcatcgtt ttgctttgca gcttttctat acctcatgtc taataaaaga cataagcttg
    10681 ccgataagaa cattacccca acatagaaga atagattggt ctcatcgcca gtctttagta
    10741 agatggtatt ttgatgcttc atcggtttgg tagctgttga aacatgcgga cacttggttt
    10801 catttgtcgt cgatggtatt gtcggacgac ttggcttagt gttattaggc ttatgattgc
    10861 cttcactact gcttaccttt ttcttccact gtgcaaacaa ttcattagga aacggcaggt
    10921 cattatctac cctaatgtca tcacctacct tttttaacct cctgctcgat ctcttgttgc
    10981 atacaaaatg ttatacagat acttctgtca gatagagttc ttgcttttgt ctcttgactt
    11041 ggtgattcaa aacacaaaaa aagcctgcta gatagaacta gcaaggcttt aagattagtc
    11101 ttgttcaaaa tagaacttat ttttcatcaa tgactaatcg aacctttttt cctaaagttg
    11161 gcaccgaata gacaatcgat cttatcgctg tgatggtacg acctttcttt ccgataacac
    11221 gaccgatgtc ttgagcatcc aagtcaagat ggtactctaa aaaatccgga gtatcttcaa
    11281 ttttaatagt aagcttatct ggttgtgaaa tcaagggctt cacaatagcg ataatgagat
    11341 tttcaatggt atccataggc ttttattact tagaaaattt ttgatcgtgg aatttagcca
    11401 taaccccagc tttagataga aggctacgaa ctgtatcaga aggttgtgca ccttttccta
    11461 gccaatcaag aacacgatct tctttaagag ttacttgatt ttcagctaca agtgggttgt
    11521 aggttccaac tgtttcgatg aaacgaccat cacgtggtgc acgtgaatct gcaacgttga
    11581 tacggtagaa aggttttttc ttagaaccca tacgagttaa acggattttt actgccattt
    11641 taatatgtct cttttcttta aatgataata gtcaagaaat gtagtcctgc tcatttctca
    11701 cctaactagt atactttact tttgattatg tgtcaagttt ttttcttgac acttttttat
    11761 gatcataata ctactcaaca tcttcaatca gctaagctgc ttagatgaca tcaaacagca
    11821 ggcagctgct cttataagag catacaactc caaactaacc tactctagtg atccttagcc
    11881 gtcaataatg ggatcaggca agcataactc cccgtcaaag gagcggtttg tttcacagca
    11941 aaaaggcgaa ataaactgac aatcacatca aaaaggacga gcccctaaac atgcaggagc
    12001 tcgtcctttt accaatatga cttagtctct ccttgctttt aaggctaggg tattagctaa
    12061 gcgttacact aataatgcat caaaatatgc ttaagaaact ctccaccata aatccaaaaa
    12121 taactgaagg tcaaaattga aatgggtcta caaattagga taatcagtaa aaagcgcttg
    12181 taggtcatct gactcaatcc agtaatcata ataagagcat cggcaggggc taagggggaa
    12241 atcatattga gaataaagaa acgctcaaat aatttcgttg atagcttctt ttcataaaac
    12301 tgtagctgct ccatacttaa aaacagtaag ataaagggct ttccgtatct cctcaccaac
    12361 tgaaacaaaa tagaagatcc aatgcagata ccaaacacat ttaacataaa gcctaatata
    12421 ggaccaaagg ctagaaagcc aacgactgtt gtcacaccac caggaatgat aggaacaact
    12481 acctgcacaa tttgcaagat aaaaaagcaa atggcaccga taaggagatg atccttgatt
    12541 aaatgggcta aagcctttgg attattaata atatctagct gcctaataag gtagacaaca
    12601 agcatgacgg agaacagaat tgataggcca ccaagaatct taaacagctt ctttaacaac
    12661 gaatgtgaaa caccaaagct actcatagcg caaagcctct atcggatcaa gcttgcttgc
    12721 tttgtttgct ggcagcaatc caaaaataat accaattgat gccgaaaaga taatagctac
    12781 agccgcaaca tctaaggaaa cagctgctcc ctttaattgc atcgcatttc ctagcacacc
    12841 tacacacatc tgtgctagca gcagccctaa aagaccgcca attaacgtca acaccactga
    12901 ttcaatcaaa aattggctaa gtatcttcaa gcgcgttgct cccaaggctt ttcgcaagcc
    12961 aatttcacgt gtacgctctg ttacagatac cagcatgatg ttcataacac caataccacc
    13021 cacaagaagg gaaattcctg caatggaccc aacaactgtg gtcatgatac taaattgtgc
    13081 gttaatgtca ttgataattt ggctattgtc aggaacagcg tactcgccct ccttaacatg
    13141 agacagtgtg gtcagcatag cagctgcttg atttcctaat tcaaggcttc gcttaacgtc
    13201 gccaatataa agataaacag agccaatttc cttgacatga aattctgaag ccacctgggt
    13261 attggccata atggctcctc cagaaatccc accagcaaac gaaacaacct cctgatcagt
    13321 cttgtaaaca cctactacaa ggtagtcctt actatctaga ctaaccacct tatttagagc
    13381 ttgttcataa ttgcctttgc caaataattc gtcagccaag acagtatcta ataggataat
    13441 gcgagaaaaa tttttataat ccttgctatt tagcgtccta cctgcaacaa tatcatattt
    13501 tttgacttta aaataatcct gactaacccc agtgatggcc acattgtcca tcttcttttt
    13561 ctcaaaggaa atggtagagg ttgaattatt ggtatagtaa taagaatcta ccccatcaat
    13621 tgctttgaca atctgctcta gccattcagg cttgacctct tgctcatttt catgcgctgc
    13681 aaaggccgcg taagggttgt cctcatctcc ttttgccttg aaataaagct gaacctcttt
    13741 ttggtcattt gaaaaggaat ccgtaaccct ctttgtcatg gcagcaccaa gccccatgat
    13801 aatcacaaca gcagctacac cgataataat tcccagcatg gtaagaatcg aacgcagctt
    13861 gtgcccccag attgaactaa gagcaaattt ccaattttcc atcacttttc ctcctagtca
    13921 atcctgacac tttctgttgt atcagctgtg atttcaccat cacgaataac aatttttcga
    13981 gtggcaaagt ccgcaatctc tggctcatga gtaaccataa taatagtttt gccttcctta
    14041 ttcagctccg tcaaaagcct cataatctgc tcaccagtct ttgtatctag ggcaccagtc
    14101 ggctcatcag ctaagataat agacgggtta ttaaccaagg ctcttgcaat ggcaaccctt
    14161 tgcttttgac cacctgataa ctctgatggc aaatgcttca ttcgcatacc aagctcaacc
    14221 ttttccaaaa attgcttagc caattcacga cgctttgata ctccaactcc agcataaatc
    14281 aagggaagct caacattttg cagggcattt agctttgcta gtaaaaagaa ctgctgaaag
    14341 acaaagccaa tctcttcgtt tctcacctga gcaagctttc gatcatttag gatctcaacc
    14401 tgtgtgccat tgagacgata atcacctgag gttggtctat ctaataagcc gatgatattc
    14461 atcagggttg atttccctga gccagaaggc cccataatag cgacaaattc accctcatat
    14521 acagtcaaat ccacgccttt taggacctgt agctcctgat caccattttg atagctttta
    14581 acaatgcttt ttaattgtat taattctttt ttctcatctg gcactactta atcacctcgg
    14641 attctttact gcttttttta gaatcttttg atgcctttgt gtctgcggaa ataacgtctt
    14701 ctagcttttc accctctttg atgttcttat cagggttagc aatgacaata tctcccacct
    14761 ttagacctgc acttacttct tgtctttcag catcagcatt gcctagggtt acttcaacct
    14821 ttttagcctt tgcagttgag tcatcataga cccagacaaa atgcttcttg cctttgttaa
    14881 cgatagcagt aactggtact aaggcatgct ttgcttcgtt gataacctca acagacaccg
    14941 taaagccttg ctttagctgg ttaagcggac tcgtgatatc aattttgtag tcataggtcg
    15001 caccagttga gcttgatgag cctgagcctc ctgcagttga accacctgca ttggcatcgg
    15061 ttgggtagtt tgacacataa gaaatctttc cggtccactc ttgatcagca tagacctttg
    15121 atttaatctt cacagcttgt ccaaccttaa tattggctaa atcatactct gttagggtcc
    15181 ctttgacctg taacttgcct tcggttgcga catgaaccaa ggtttgactg ttttttgaag
    15241 acgggtcaat atcattatta acctctacaa ctgtccctga aacaccactg acaactactg
    15301 tttcatttaa ggcctgctgt gctttattga cctctgcttg agcatcagca taggaatcat
    15361 ttaaatcctg caattgctga gcatagctag cattttgctg ggctgagggc tgaatggttg
    15421 tggtggtttc ttgccctgtc tcctcgtcct tgcttgtctc agtagttgct gctggaacac
    15481 catacgtttt taaatgatta atctgacgcc caattttatt gagattgcga acagcggtgt
    15541 cataagctgc ctgtggtaca gttgtattgt actgtactaa ctgctggcct tgtgtgacct
    15601 gatctcctac cttaaccgta acggtagcgt ctgagccttt gctagcatca aaataaacat
    15661 attcttctga aagagcttta acagtaccag agagtaaggt tgaagaggct attgtccctt
    15721 ctgttacatt taccgcagaa taaggtagct tgatattttg atcagagata gtatcttgct
    15781 gttgcttcca caatactcca ccgataacga ctacagttag tgcaactgca cctgcgataa
    15841 tgcctttggt tttcgttgat aactttatct ttcctctttt agacatttct gtcctcccct
    15901 tttgtactat ttttgtaaga caagtatatg atgtttttaa aaacttgtca agaatttctt
    15961 ggataagctt aataaagcag cctcttcatc atgtagatga caactctatt ataatggttt
    16021 ttcaagctgt actagcttac acttttgtaa tattaaaaag aggcaaagac aaaaagagtt
    16081 gtcctttaac tttattacac agtctcattc attaaaaagc gaacaagcct agttttcaaa
    16141 atctcagaaa actagacttg ttcgtttgtt tagacttttc tctcagtctc ttcatcaggt
    16201 ttaaatagct tctatactaa aggtacggct ttcaagaact ctcagcattg ctactgctgt
    16261 atccaatgct gtaaacagag gaactccttg ttcgattgct gagcttctga tcatctgccc
    16321 gtccttatca gtcactcgtt ttgttcctac ggtattaata atagcttgaa tctgcccttt
    16381 tctcagtaag gctgggatat catgagcatt gtcgccaatt tttccaacta gctgtgaatc
    16441 tagcccttgg tcagcaaaga aagcagctgt gccttcggtt gccatgatct ggtagccaat
    16501 agcactaaag cgtctagcta agatcagagc ctccgactta tggtcatcag cgatggtaaa
    16561 aactattgtt ccatattccg gcatgtgcag atagctagct tcaaaggctt tgtaaagggc
    16621 tttttcaagt gttaaatcag agcccatgac ttcaccagtt gatttcatct caggccctaa
    16681 aaggctatcc accttagcga gctttgcaaa tgaaaaaacc ggtgccttga tatgaacaag
    16741 cgagctttca ggataaaggc catcttgata acctaagtct tttaaggtct gacccagaat
    16801 aagcttcgta gcgacttgtg ccattggaat attggttact tttgataaaa atggcactgt
    16861 ccgactggca cgaggattga cctcaatgac atagacctgc tcattttgga tcacaaattg
    16921 gatattcatc atgccaatac agtttagccc tatagcaaga cgcttagtgt aatcaacaat
    16981 cttgtcttga acctgtttag ataggtgctg cggcgggtac acagccattg aatctcctga
    17041 atgcactcct gctctttcga tatgctccat gatccctggg attaagactg attgaccgtc
    17101 agagattgca tctacctcgc attccttacc aaggatataa gaatctatta aaacaggatg
    17161 ctcaggacta gccttgacag ctgttttcat gtaggagcgt aaatcgtttt cattttcaac
    17221 aatttccatt gctcggccac caagaacata agagggtctg accaataccg gaaagccaat
    17281 ggcacgcgct gcctctaagg cctctgcctc attggtggct gttttcccag gaggctgagg
    17341 gatccccagc tccttcaagg ctttttcaaa aagctcccta tcctcagcac aatctaagtc
    17401 ctctagctgt gtgcctaaaa taggaactcc ggccttggtt aactgctctg ctagattaat
    17461 agcagtttgt ccaccaaact gtaggattac tccctttggc tgctctaatt caataacgtt
    17521 catgacctct tcaaaggtta agggttcaaa ataaagcttg tctgatatcg aaaaatctgt
    17581 tgacactgtt tcaggatttg aattcatgat aatggcttca tagcccgcag cctgaatagc
    17641 cttgacagaa tgtacggttg cataatcaaa ctcaactccc tgaccgatgc ggataggacc
    17701 agagccaagg acgataacag attctttctc ggatttgatt gattcgtttt cccactcata
    17761 ggtcgagtaa aaataaggcg tttgtgagtc aaattcagct gcacaggtat caaccatctt
    17821 ataaactggc aagacacgat aggctcgcct taaccgtcta atacttgcag catcagtttg
    17881 ccaaagctct gcaatttttt ggtctgaaaa accatatcgc ttggcttcta tcagcaaatc
    17941 gatatcaact ggctttttaa taaggtcttg ctccagttct acgatatgac gtaatttatc
    18001 caaaaagaat aaatcaatct tggttaagcc agctagctct tcaatactat agccacgacg
    18061 aagggcctca gaaagataga atagacgatc gtcctgtgct cttacaatgt gagcaaccag
    18121 ctcatgatca ctgatagtat ctagaccctt cagttcgtta tggtgtactc caatttccaa
    18181 cgagcgacaa gcctttaaga gacattcctc aatacggcgt ccaatagcca taacctcacc
    18241 agttgctttc atctgggttc ctagacgacg ctccccccgc tcaaacttgt caaatggaaa
    18301 gcgtggcagc ttggcaacca cataatcaag agctggttca aacatggcat aggtggttcc
    18361 tgtgaccgga ttaagcatgt catcaagcct taagccaact gcaattttag cagctatttt
    18421 agcgattgga taaccagttg cctttgaagc cagtgctgat gagcgagata cccgcggatt
    18481 aacctcaatc acataatagc tgaagctatt gggatcaagt gccagctgaa cattacagcc
    18541 tccttcaatc ttaagggcac gaataattct caagctagca tcacgaagca gctgattctc
    18601 aacatctgat agggtttgtg tcggggcaaa aacgattgaa tctccagtat gtatccctac
    18661 tgggtcaaaa ttttccatac tgcaaacaac cagcgcgtta tcagcagcat cacgcatgac
    18721 ctcatattca atctctttaa agccggcaat ggagcgttca atcagacact gggtgacagg
    18781 agatagcttc aggccattct ccacaatatc tcgcaagacc tcttcattgg agcaaatacc
    18841 acctccagtg cctcccagag taaaggcggg gcggacaata acagggtagc caatggcatt
    18901 tgcaaagccg atagccgcct ctactgtcgt cacaatctct gattctggaa taggctctcc
    18961 caactctttc attaattgct taaataaatc acgatcctct gcctgatcaa tagcagataa
    19021 ggttgttcca agcagctcca ctcctaattc ttgtaaaata ccagccttag acagttccat
    19081 cgccatgtta agaccggtct gcccacctaa ggtcggcagc aaggcgtctg gtctttcctt
    19141 tcttaagata cgactaacaa atgccaacgt caggggctcg atataaacct tatctgcaac
    19201 ctctttgtct gtcataattg tcgcagggtt agaattaacc agaacaacct gatagccctc
    19261 ttcctttaag gctaaacaag cctgtgttcc tgcgtaatca aattcagctg cctgcccaat
    19321 aacaatagga ccagacccta tcaccatgat ttttttaata tctgtacgtt ttgccataat
    19381 atctggtaca aaaggcctta acaatccgaa taaaataatg caagcaccta acattaaagc
    19441 atcacaatct attttttact aggatttgta cctgtactca gctgcagcaa gccctttgta
    19501 cctactcctt tcattatttg ccgtctcaca gggcggcatt aaataaaaca cttaacagtc
    19561 tgtcacatga gacgatgagt acaagatcaa gtaaccctta gctcagcaag tatagatgac
    19621 ttaattgata tagtcttttt acttctaaag agggcgatct tgccagcaaa tactagtcat
    19681 aacccgcggc agagcgatca tttcccacta gtctatctgc tgcctgactc aagctgtttc
    19741 atgacagctg atcaagcctt tggtgcttgc tttttgatct gctagcacac ttgattaaca
    19801 tttgccttgc tgctctagct gccaggcgtc aatcatatct aaaaattcat caaatagata
    19861 gctagcgtca tgagggcctg gtgcagcgtc tgggtgaaac tgcacagaaa aggcgggaac
    19921 atgtcgatgt ctcacccctt caacagtttt gtcattaatc tcctcgtgcg taaccatcaa
    19981 gcagtctggc aagctgtcgc gctcaacagc ataaccatga ttttgactag taaaatcaat
    20041 acgtccggtc gctatttctc tgacagcatg attaaagcca cgatgtccaa aaggcatttt
    20101 aaaggtctta gcgccattag ctaagctaag cagctgatgg cccatacaaa tgccaaaaat
    20161 tggaattttt ccttgaacac cacgaatcat ctccaaggcc tccggcaaat cctctggatt
    20221 acctggacca tttgatagca ttagaccatc tgggttgagc tgtagaatct cttctgctgt
    20281 gatatcaaag gggactattg tcatctgaca ttgccttttg gataattctc ttaaaatgga
    20341 atgcttcaag ccaaagtcca ccaaaacaat atttttccca acacccggag cgggataggc
    20401 agtcttagtt gacacctgct caataccatt agtcggaagc acagttgcac gcagctgatc
    20461 ctttaggtgt tcaagcgtat caccatcatc tgccattgtt gccttcatcg taccatgctg
    20521 acgaatgatt ttggtcaacg ctctggtatc aattcctgaa atgcctggaa tccccttatg
    20581 ctttaaaaac tcgtccaagg tcatttgctg acgccaattg ctagctatcc tgcttacttc
    20641 agagacaatg acccctttgc aagttggggc aatggactca taatcatcac gattaatacc
    20701 ataattacca acaaggggat aggtaaatac taagagctgc ccgttatagg actggtctgt
    20761 gattgactcc tggtagcctg tcattcctgt attaaagaca atctcgccag tgacatcaat
    20821 atctgcacca aagggctttc cttcaaaaat ggtgccatcc tctaagataa gtaaccgttt
    20881 tgccatttta accccctcta acatgccttt agaccttatc gtttctgcca ttaaggatcg
    20941 cttcgataat ggccatacgg acaaatacac cattagccat ttgagctact attcttgcct
    21001 ttggagcctc tactaaatgg tcagcaatct caacatcgcg attaaccggt gccgggtgca
    21061 taataatcgc agagtccttt aaccgcctgt agcgctcctc agttagacca aactgtctat
    21121 gataatcttc cttggaaaag ctttgactac catcatggcg ctcatgctgc accctaagca
    21181 gcatcaacac atctaattga tcaataatgt gatcaatcgc catgtacctt ccatagctgt
    21241 caaattcaga cgagtaccat tgctcaggac catagaaata aagctctgct ccaagccgct
    21301 ttagaatctg catgtttgat ttagccacac gagaatgtgt caaatcccct gcaatagcaa
    21361 tcttcaggcc atcaaaatga ccaaattctt cataaatagt tagcaaatca agcaagcatt
    21421 gactagggtg ctgacctgat ccatcacctc cattaacgat agaggcagta atcgttggac
    21481 tgtcaataag ctgctgatag taatcatctt ctgggtgacg aatcacgcag atttctgttc
    21541 ctagagcact catggtaaga acagtatcat ataaggtttc ccctttattg acagcacttg
    21601 tatcagcgtt aaaatcaagg actctaagac caagcttgtt ctcagcaacc tcaaaggatt
    21661 tatgggttct tgttgaattt tcaaagaata aattagctgc aaagtgccta ctgttatctt
    21721 taatagctac cttacctgcc ttgtattcag agccacgact aataagtcct aaaacctctt
    21781 catttgttaa atgctccatt gacaccaaat gcttaagcgc aacacgatta tttacaactg
    21841 acatgattta tcccctttta ccaataatga aatgatgata acaattgaca acagctacac
    21901 actagttttc tggaagaagc tgatacaata taatgccaag aagcgttgaa aaagcaacac
    21961 ccgaaatctg aaggccattg atttgaagca tgaggcctcc aataccagaa accagaataa
    22021 cactagcaat caataggttt ttcttgttgt ccatatcaac cttagcttca atcaggattt
    22081 tcaagccact agaggctata accccaaaca gagcaatcga aatccctcca atcactggag
    22141 taggaataga ctgaataagt gctgatacct taccaacaaa gcttaacaaa ccagcaatca
    22201 cagcggcacc tgcaataaca tagactgaga agattttatt gagggccatc acaccaatat
    22261 tttcaccata agatgttacc ggaggcgctc ctaaaaatcc agcaatcacc tgtgcaaggc
    22321 catcacccgt caaggttttt tccaagccag gatccttgaa ataatctctt ttagtcaggc
    22381 tattaagcac catgatatga ccgaaatgct ctgtcatggt gacaaaggca atcggggcca
    22441 tcgttaaaat agcactagga tacaaggtaa tgtcataggt taaaaagggg atagccacag
    22501 ctggaacact gagccattgg gccttagcaa cctgtgtaaa gtcaacaata gactgacccg
    22561 tcaccatacc aacaaggatc gcaaacaaat agccaaccaa taagcccaac aaaataggaa
    22621 tgatggcgac aatcccttta ccataaatgt taaagaaaat aatcgctaat aaggtgacaa
    22681 gaccaatcaa aaggtataac aggttatact ttccatcctt tagcatgaca tcactaactg
    22741 ctgttgaggc caagctaaga ccgatcacca taacaatggg accaaccaca actggaggta
    22801 agatcttatc gatccattca ttgccaatcg ccttcaccac cagtgctaca accagataaa
    22861 ccaggccacc tgtaatcgct ccctgtgcaa ctgcaccaat accatctgtt ttcattagca
    22921 tttgcatggc tgcaatataa gcaaagcttg agcccatata agcgggaatt ttaaatgttg
    22981 ttactgacaa atgcgccaga gtcccaagtc cacttgataa gagggcaact gacggatcaa
    23041 tcccaaccaa aattggaacc aaaacagttg ctccaaacat agcaaataaa tgctggaagg
    23101 acaagccaag caaaatccct gcctttggca cttcttctac atcataaatg acatctttca
    23161 cacaatcacc tctttcttat cccggatcaa caatactaat acgatcttga ccgtcaacct
    23221 caaccacctc aacgacaatc tcttctgtct tgcttgtggg aatattcttt ccaacataat
    23281 cggcccgaat tggtaattca cgatggcctc gatccaccaa aacagctagg ctaacacgtc
    23341 caggacgccc taagctaacc aaattgtcga tagctgcccg aatcgttctg ccggtataaa
    23401 gcacgtcatc tactaagata atatccttgc cggtaatatc taccggcatg ctggtggtgt
    23461 cctcttccac tctcatatca tctctaaagg gcttggtatc tagctctcca actgccaagt
    23521 gcaggctttc tagctgctct aatctttctt gaatacgacg agcaaggtaa acacctcttg
    23581 ttttaatccc tacaagcacc acattgtcta gttgcttgtt gcgctcaata atctcgtacg
    23641 taatccgcgt gatcgcacgc ttcatggtta gctcatcaac aattaccttt gatttcattc
    23701 aaagcctcct caaaaaattc aactaaaaaa atctccctgt taacaaggag attcagcaaa
    23761 acaggcacac agctagacat aactgtgcac ttttttattc agaacatgct ccttgccagc
    23821 ctcacaggac tgttttaaag gaatatttta ttttcattag tatagcaaaa tcacaagcca
    23881 aaaacaagga ttttctaaaa aataattcaa aatatataga gctatcacag caccaaggaa
    23941 aatgctacta aggtcatcag caatcctcca acacaattcc aaaaataggt cttaagacct
    24001 attgtatttg tatcaaaaca atagtacaat aatatcaaac acaaaggaga gcgtttatga
    24061 tgaatgatat aactagaaag attaaccata agcaactgat tcaaatcact accattctag
    24121 gcattattgt taccatcgtt attttgttct atctgcagca gcaccctaat ctttttgcag
    24181 ttggcggtcc ttttcagacc tatcttatgg aacttggtat cctagcaccc tgtttgttta
    24241 tactgcttca aatcattcaa gtggtttacc ctatcattcc tggaggcttg acctgtgttt
    24301 tagggcatgt agtctttggg ccgttttggg gatttcttta taatactcta ggtattttta
    24361 ttggttcgct gcttagcttt atgctcgcta gaaaatatgg tgaacagttt gctaaagcct
    24421 ttgtatcaga tgatacctat aacaaataca ttccttacct caataaaggc aagtactttg
    24481 aacgatttct cataacagcc tttattctcc ctggctttcc agatgatttt ctctgtatgg
    24541 tagctggact aagcagcatg tctatcaaaa catttaccag tattttcttg atatcaaagc
    24601 caattactct ttatatctac acccttcttg cttaccaagg catacaaatc gttggacagg
    24661 tattgcaatc ctaaaaaaag ctagtattaa gctatcaagc ctgattggaa tacagtattc
    24721 caatcaaaaa ggcgctcagc ttggtaccag ctttttatcc ttgtcttagt tgctccaaag
    24781 tcctttggaa gatttctggt ggctcaacag taaagaccag ctcctctcct gtcacagggt
    24841 gggttagtcc caatgtttgc gcatgaagaa actgcccctt gccagccaag gtcttacgag
    24901 gaccgtagag tggatctcct gcaagagggt gaccaatata agccatatga acgcgaattt
    24961 gatgcgttcg acctgtttcc aattgtaatt ccacgaaggt atagtggcca aagcgctcca
    25021 aaaccttaaa aagagtcaag gcttccttgc ccttagcagt tacggtctgt tttttacgat
    25081 ccttttcact gcggccaatc ggagcttcaa ttacacctcg atcctttggt aaattaccat
    25141 gaacaatggc cacatacttt cgtaaggatt tcttagcctt gagctcatca gctagtagct
    25201 ggtgggcctt atcggtcttg gcaaccatta aaagaccaga ggtatcctta tcaattctat
    25261 gcacaattcc tggacgaata acaccattaa tagaagacag gtctttgata tgatagagca
    25321 aggcattgac cagcgtccct gtagaatgcc ccgcagaagg gtgaacaacc attccctgag
    25381 gcttattaat aatggccaat acatcatctt ggtagacaat atctagtggt atatcctgag
    25441 cctgatagtc caagctgctt tcctctggga tatgatagct aatgcagtca cccacctgca
    25501 caatatactt ggccttctta ggtaagccat tgaccaatac ccttttttgc ttgatctgat
    25561 cattagcctg acttcttgat aatggggtca aatcagccaa ggccttatcc aagcgatggc
    25621 ctgattctgt tatcttaatt tccatagtcc tcttctttcc atagacaaat gaccagcagc
    25681 aaaacaccta tcgtcaaata ggaatctgcc acattaaaaa tagcaaaatt gatcacatct
    25741 aaatgaatca tatcaaccac ataggataac ctcaagcggt caataaaatt cccaagacct
    25801 ccagatataa tcagcaataa agagagctgt agccaaaagc tagcctttgg gtgcttcaac
    25861 acataataaa tggcatagcc aaccaccaaa acagttatga ttgtaaagaa ccactgctga
    25921 ttctgtagta tggaaaaagc agctcctcga ttttgaagat aggtcaagct caccaaacct
    25981 ggtataaagg gcttcacctg ccctagctca atatgtgtaa cagtccacca tttacttagc
    26041 tgatccagta tcattaagac aatggcagcc ataataaaac taattctttt caactaatcc
    26101 tattcctttc agcttaaaaa caagagatta ccttgatggc ttcaaaaaag caacaacagc
    26161 cagctgtctc tgtagcgtac tcaaccttaa agcctccaaa aactggtatt ctagtaacct
    26221 tttagtatca ttgatagtca accacacagc agctctagac ttgactttat atcaacaagt
    26281 ctcaccacag cagctcgctt aatccttatc cataccagag ctaagtccca ttgtctatag
    26341 cttgcttttc ttttcgatgt tcaaaataat cctgtaaaat ggtcacaaaa tgtaaagccg
    26401 cagcagatag gttcttatcc ctacgcttga cataaatcat tttatgctcc atatgatcac
    26461 gcaagggaat aaccttgatg ccattaacgc tttgctgatc taaaaatcca gaccctgttg
    26521 caaaggcagc tgtcctttcc aaaatgccat ttaaggttgc cctatctgac acagtgtata
    26581 tgtgaggact cttgcttgtg tcaataaaat tttctgaata ataaagatat tcttcttttt
    26641 cttgagtaaa gcgtaccgct ggcagccctt gcaaatcctc taagaaaagg gctttccttt
    26701 gagccaatgg atggtttttt gataggtaaa tatgggttgt aaaggatagc aattcaacat
    26761 aatccaaagc cagcttatcc attcgctgaa aaagcccctg acggttttgt gcattaagat
    26821 agataattcc aagctcacta tttccctgtg ccacctcatc taaaatttgc atagtcgttg
    26881 actcaaaaac tctaaaaacc ttatgcccag catgcttttg ggaaaatgct gttattaaag
    26941 ctggtaaaaa atcataatgc tgactcgcaa ttgaaaattc atttggctcc aaagccgatt
    27001 gagaaaactc cttttccagc gagtcaaagc acttaacaac ctctaaggcc ttttcataaa
    27061 ataaaagccc ctggctggtt aacacagttc ctgctgttgt cctacgaaag atctgaaagc
    27121 caagctctgt ctccaaatcc ttcactgaaa cagacaaact gggttgactg acaaatagct
    27181 ttgaagcagc ctcacgaaag gtaccattat ttgcaatagc aaccacatat cgtaattgtt
    27241 gaatattcat taatccactt cctaaatcta gtacccttca ttataccata aagccagcca
    27301 atgaaaaata aaggcgtcca tcttaaccat gccaaacgta tctacagata atcatgagat
    27361 agcattgact ttttcaatag tgtcttatca tatttagcta tagaaaacag ccttactata
    27421 agttatactt ttgaaagaag taagccttag atcacagaac atcacactga gattttttat
    27481 gcgcttatcc tgtctgtcca agaactgaga attggctaca tctagctaat aagccatttc
    27541 aggattttac tgtctaggag ttatttatag gcaactatta cagtaagata gtgtcacaat
    27601 acaaaaaagg ctatcccaaa gtacagaaca gccttatacc gtgccctttt aacacattat
    27661 tttgcgattg ggtatacaga aacttgtttc ttatcgcgtc ccttacgctc aaagcgtaca
    27721 acaccttcaa ccttagcaaa aagagtatca tctccgccac gaccaacgtt aacaccagga
    27781 taaatatgtg tgccgcgttg acggtaaagg attgaacctc ctgaaactgt ttgtccatca
    27841 gctgccttag cgccaagacg ttttgcttgt gaatcacgtc cgttagaagt tgaacctcca
    27901 ccttttttgt gggcgaagtg ttgtaggtta gaaagattaa gtttaatcat ttttatttcc
    27961 tctcgttgaa tttaattcat cacaggcttt tgaacatatt ctgataaatg ctctgccaaa
    28021 ttctccaagc caatcacaac agactcaaac agaatttgcc acacctgctc ttgttgctca
    28081 gtaaatccct caggctttgt tacccttagg aatccaccac catcgaccat ttctagtgct
    28141 ggctcaagac ctgtcatctg ttcaactgaa ttaacaagat tgaaggccaa aactgaaacc
    28201 gaagcacaaa ctacatcaaa gccgtactca ccgcttccag catgtcctgt gataagcatc
    28261 tcagtccagc cagctgcgtc ttttgttaac cgtactttaa tcatgtcaaa ctagaattat
    28321 gccttgatag cgttaatcac aactttagtg taaggctgac gatgaccttg cttacggtgg
    28381 ctaccttttt taggcttgta cttaaaggtt acaaccttct tttgttttcc ttgcttttca
    28441 acagttccaa cgacagtagc tccctcaaca actggagtac caacgacagt cttatcacca
    28501 cctacgagaa caacctcgtt aaaagtgatt tctgcgccag cttcagcgtc aattttctca
    28561 acgtagattg cttgacctac ttcaacttta acctgttttc caccagtttt gatgattgca
    28621 tatgtgctca tgatgcacct cctataagat ttttgatgag gtttccctct gtgaagactc
    28681 gcctagaatc gtgagagcca atctacttga aaacgatttt cgtgcggttg cacaggacgt
    28741 gcacttagtc aacgttacaa ttttaacatc aaatttgatt tttatcaaga aaaatatgct
    28801 tttatcttcc taaaatctta agctatacat aatcacagct atgtaaaggc tagcaatgct
    28861 ttaccatttt aggttaacca gggcattcat ttctttataa gcaatagctg ctttttcttg
    28921 cgtttcggga tcaatcttat cataatatct gccgcctttg ataaagtcct ccaaaaccat
    28981 ggtacgatag ctatatagct catagccttc actaccataa aggcccttag gcttagctaa
    29041 aaccattgtc gggtgagcct ttactgtttt tatttttgtt ttttgcccct tcttctcaaa
    29101 ggtaaggtcc attagcacgc cgcgctctgt ccaaatatca tcaacagtct ctaggcgttg
    29161 attggaaatg aaattaccca ttgaatagat aataaatttc ttttccttgt ccttaacaat
    29221 cgtctctgcc ggctctacga cgtgggggtg acctcctaag acaacatcag caccccagtc
    29281 aatcattttt cgataaagag ttttttgctc agctgttggc tctaaagcat actctgtgcc
    29341 catctgcggc ataacaatgg taatatcggc ctctttttca gcacgcaaga tgtctttttg
    29401 tatcttttcc tcattaaggt cagacaggtg cttgtcatac tcctcctgac tgagtgtcgc
    29461 ctccattcca ttatagccat atgaatagcc caatattgca atcttaatcc cattaacctt
    29521 tttaatgaga atgttctcct tagagcgatc ctgctcataa ataccaatgc tgtctatccc
    29581 catatcagca aaaacacgct tggtattgag agctccttct aatcttgagt ccaaaatatg
    29641 gttatgggcc aaatcaacca catcatagcc agtatgctta agcgcagcag caatagcctc
    29701 tggcgcatta aacaaaggat agccagctag aggatagtct ggactgatcg ttccctcata
    29761 gtctccaatg gccaaatcag cctgactaat ccaatccttc acatactcaa aatagggatt
    29821 aaaatcatag ctaccatcag cctttttagc actcatatag agaatatcat gaatcaaaat
    29881 atcaccattt gcgacaacac gcgctgtttg tgtcttttga ggtgtcttgc ttttcgtttg
    29941 tgtgcctttt tttgacatgc ctaataaatc aaaggccaac ccaaaaacaa gtatcaccac
    30001 aatcaaggta agcactgaaa gcatggtctt tttatactga aaatctttta gcaagcgtca
    30061 aacctccttt tttcctatta taccatgttg acacgacttt ttaataacaa atcccaaaga
    30121 aaaggctatg cccatttaag aagaatgcct tagacagcag catagactcg tattagctag
    30181 tcaaaaaact agattgctcc tctttggttg atgtcatata ctttgagcct aaatagcttt
    30241 caacaaagtc taatagttga ataatgtcat gcaaaatatg gtataatgaa acaaaatcaa
    30301 actagtcagg atagtcacat gaagcataac tctttcagcc gctcactatt actccccctt
    30361 ctcatctgtt ccttgtctgc ttgctcttct catacagaga aaaaagacca taccaaagac
    30421 gctactgcta tcaccgatac ccgaaaagca gagcatcagg acatcagggc aaatatggaa
    30481 aaggtcaagc tcgctaccgc tagcaccgac ttcaaaggtg gctcaagcct tgaggagcta
    30541 atcactattt ttggacagcc tagtcagcac gaagaaaaag cagctggtag tgttactctt
    30601 gactcctaca catggcagtt tgaccatgtc acggttaata ttaacctcta tgaaaacagc
    30661 agcattgtta aaactattgc taactttgct tttattagag acctgacctt atccttaaag
    30721 gactacaaca gcttgaaaaa gggcatgacc tatgatgagg tcaagcagct attgactgag
    30781 cctgataatt acagtcaagc caattccagt gaaaaagaaa ccattcaagc catttggatt
    30841 agtggcttaa aagctcagac acagggtgcc aatatagcac taacctttga aaacaaccag
    30901 ttgacagaaa tgtcacaggt tggtcttgaa gactagtttg tggataaccc caatcatatt
    30961 aatgatagaa aaaagcttga tatttaataa gatcaagctc aaacgataga ccaagtagct
    31021 gatgatcttg acagtaatgt gtaacaagct gagatactac tcactaggca gtatttacta
    31081 gcagccactg aatttccttt atgatgacag gcaaccacct tttttgtggt gacctatcaa
    31141 tagcaccata agctctcttt tgtcacatac cttgcttaac attattttac caggtatgtg
    31201 atgagctttt taggttgtct gatagtataa catctaaccc ctagttgatg atgtagataa
    31261 ggcaagagct gctaaggata gcaccataaa taagatccaa catagggtca tattatatag
    31321 tgccaagaac gaaaagataa agacacctac agggagcgat aaagagaaca gaagacctaa
    31381 aaagttattg ctttgggcta gcatatctga tgggagattt tccattaaaa gggcgtccag
    31441 cttgggtgtg gcttttccca taatataagc tgcaaaggct aagcataaaa cccctatgat
    31501 ggcaggtaat tgcagagcat tagagactcc taccagcaaa aatgctatgc cctgagtctg
    31561 tactagcttt gatattgaaa gccttgaaaa gtaatccttt ggtgttagat ttcccaacat
    31621 cgctccgata atcgtaacgg catcaacaat aactaaagac tgcccataat gaaaatgaaa
    31681 tagctgatga tccatcaaat aaaaatgata aatgctatta attgctcctc caatagcgtt
    31741 taaggtcaag atggataaga gtaacatcac aaaagagata tgatcaatct ttttaaaggt
    31801 ctctgtcatc cttgtataca tcaccttaaa ttgcttcatt aatgaaacac ctgcttcaga
    31861 agcttcaacg acatcatgcc ttagcttttg tcgattttta agaagcacaa cagatgacaa
    31921 taaaaaggaa atagcattta tcaaagcaac aaaggcataa ttgttgcctg atgtcgttag
    31981 cagccaaact cctaaagctt gtcctgcaat actagagagg tagccgataa attgagcaaa
    32041 agaataggcc tcatagagct tttctgattc aatatttttc tgcattatcg ggagacgtaa
    32101 gccatttttg taatcactta gaatatcaga aaccacattc aaaaagccca caaaggcaaa
    32161 taccaagaac gtctgatttg tcatcaacaa ggctacaagc gtaaataaaa gagattgtat
    32221 aaaaccaata acaataagat ttcttgtttt cctttttgtc ttatctgctt tgacgccaat
    32281 ccaaaaggta aacaccatag gaatgatggt gatgatattg gctataaaaa cagcaatatg
    32341 agaataaggt agcgtggttg cataaataat aaaaacaata ttgtaaatat aagagcctaa
    32401 agcacttaaa aagtttgaaa ctgtcagtgt tctaaaaacg acatttttaa tcaatcccct
    32461 catttactta cctgttgacg tcctttctta tgtcacctta ctttacttga ttgaatatac
    32521 ttacagcata tctaaattcg tactgtagtt ttatatggtg ttctgacatg attttgctac
    32581 taattagtaa ttcacaagcc ttttctaagt ataaagtatc gtttgttagt ctaaatactt
    32641 gtaaaagtgt catggctatc cccagcattc cgttccatag accactaaac tgagcaaatt
    32701 caactaataa cgactccgat aaattcttaa tatctttaat atatttatcg gagttaacgt
    32761 aaataagcaa ttgaacgatc ccagcagtcc catttgataa gtatggagat acagaatttt
    32821 ctgatattaa tacaccccga tttccatcgc tatcttcaac taagctttct agaataaaat
    32881 caattccttt ctcaataatt tcgttatcat aagaaattga agacagatag aacaatactc
    32941 cagctaaacc atttaaccct aaattaactt ctgattttaa ttgcatcaaa acttcatcgg
    33001 atttatccaa aatctta
//
LOCUS       DARYXS010000011        32745 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.011, whole genome shotgun sequence.
ACCESSION   DARYXS010000011 DARYXS010000000
VERSION     DARYXS010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32745
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.011"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            373..1128
                     /locus_tag="TV193_000422"
     CDS             373..1128
                     /locus_tag="TV193_000422"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEL1512656.1"
                     /translation="MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGY
                     RYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDI
                     IQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
                     VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIM
                     MEVHPTPDLALSDAAQQIDYQQLEQLGKELWES"
     gene            1187..2269
                     /locus_tag="TV193_000423"
     CDS             1187..2269
                     /locus_tag="TV193_000423"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEL1512657.1"
                     /translation="MTQTLQVKSRINDYPIIFTDDIFQPLNQFLAEKGDVKLLFITDQ
                     TVFDLYQPLFRRFQQDYDSYLHIAAPGGQSKSLEEVSRIYDRLIRANFSKKDVIVTVG
                     GGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPN
                     QIIVSAKFLDTLSEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQA
                     ICHKKRVVEKDEFEGNLRMSLNFGHTLGHAIEALCHHELYRHGEAIAIGMVFEAKLAV
                     QQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTT
                     KGYVSFPIAKHDSRLLDWLRSLLDIA"
     gene            complement(2601..3374)
                     /locus_tag="TV193_000424"
     CDS             complement(2601..3374)
                     /locus_tag="TV193_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEL1512658.1"
                     /translation="MILTQFDPDYQAIINPKDLVAEIDDFPKTVVTCFARATFNRVLN
                     ALPHRLIATTSVANLDIPIYELDVKGHKLGFFNSYVGAAGCVGVLEDIIAMGMKQLLV
                     FGTCGVLDATISENSIIIPTSAIRDEGTSYHYQPASHDIAVNQAYLTRAIDVLEQHSQ
                     TYTLGKTWTTDGIYRETRDKMIQRKQEGAICVDMECSAIAALAAFRQLEHFQFFYSAD
                     NLDADEWDARSLANEADLEAKDNIAFIALELALRLFKDN"
     gene            complement(3500..4384)
                     /locus_tag="TV193_000425"
     CDS             complement(3500..4384)
                     /locus_tag="TV193_000425"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEL1512659.1"
                     /translation="MLERLSGQTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAF
                     EVGNAELAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALAGAVNTVVNKDGR
                     GHLVGHITDGTGAIRALAEEGVSIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNR
                     KTATFKQAKQLVARINTQTSALASLQDLADDRAFRRSISESSIYIDATGVGMKPFEEH
                     RLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMT
                     GEDMPVAYIRELLCQNKE"
     gene            complement(4535..7978)
                     /locus_tag="TV193_000426"
     CDS             complement(4535..7978)
                     /locus_tag="TV193_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEL1512660.1"
                     /translation="MSVETITGSTDQSHGDIYQLHWIDKVGRCHAFSKGWRFLMADLQ
                     LAQEPFFDDSDWQQIALPHDFSINQPYTVNGEAQSAYKLGGVGWYRKYFALDPKLADH
                     KVYVTFDGAYMETQVYLNGHLIGEHVNGYQAFSYDLSAFVIPGQENLLAVRVEHLVPS
                     SRWYSGSGLYREAFLTVLPKVHLDKDRLRLSLSQAALEADSQALEIELGLSQQVPLSG
                     YQLSLSLFEQLADIQQRQTVYESKPVALDLLEESGRLVMTIPLRHIKLWSPAQPQLYQ
                     LDMLLYHKGAVLDRLTLETGFRQLHFDAECGFFLNGKAFKLQGVCLHHDQGSLGACAY
                     EEAIARQLVLLKEMGANTVRVTHNPSARRLKDLANRLGLFLIEEAFDTWTYAKNGNSH
                     DFSSHFHKTVGHQNAARLKGVTTAETTWAQYSIQAMVLSGLHDPSVLMWSIGNELLEG
                     FSADVSHYPYVAKELCQWITELDQSRPITLGDNKLKDKHFHWAQETKALAEQVNQLQS
                     VQGVIGLNYAKARDYDRLHRDNPTWLLYGSETASAINSRGVYHLKGGASQDHELTSYD
                     QSTVDWGSLASEAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGAADQWPSPKQS
                     YFGILDTAGFAKDSYYFYQSQWSKDKTTLHILPSWQEKDLQLDDQGMVEVVVYSNAAS
                     VRILFDDGHGGQIDYGIKTLTRHETPAGHCYQLYEGDDAAELPHQNLYLTWKLPYRSG
                     SLRAIAYDDKGQVLTQTSGRSCVSSYQQPAQLSWSCFEPPKLLAEPALLYLELSLLDA
                     NETLVLSANPVIKLEVEGPGACLALDNGDPRDHRPYTALSRRAYGGKLLAIIALDGRA
                     GQLRITARAAGFVEASYQLTVSEAAVNEKLLAYQLDKYSFITNETNKPSKPYARSRGS
                     AVDSLMPNPDSCLKRQGHYLPDNSVMVFSYTTALSRPLTFQPLIKRLLKGNDIILPDW
                     LQPRAAAGQLFTKAFPIDWQLTEAVFSEESRVSGQTLCFGEALELEAILKSDTKGLRI
                     NQELSLVAKKKRLFQSDTQLSYRYQYDTIQAIGAISLTGLKKPLSSLRLVLDYRSSTN
                     APSKQLILSLDQIEQPCHYIMLEEVVDVLSLDLTLEQPIRQAFDLARLQLGLWSMVEE
                     A"
     gene            complement(7992..9476)
                     /locus_tag="TV193_000427"
     CDS             complement(7992..9476)
                     /locus_tag="TV193_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1512661.1"
                     /translation="MYKVLLVDDEYMILQGLKVIIDWQALGFEVVATARSAKEALAYL
                     DDCAVDVMISDVNMPGMTGLELIEAARDVLPHLQTLILSGYQEFSYVQRAMELETKGY
                     LLKPVDKKELVAKMLYFKEWLDEQRAASLRQAAYREGLINLWLADELSEKEFFQLTQE
                     QPEAELLGFTVLYVDCKTFSPALEAFFEASKQPFYLKKAEQKKVYLVILLGQSHQAKR
                     FTNTLQERFYNTINQIILGETVVDWENVYESYNQVRRSFFYNSEVSQVAAKTNAKIEL
                     PESRLQFFSFNKTLMIGDEPTIVSKLQAIFEEMTELSFSPEDVKHVSFLLFSDIYRQF
                     PILDRTTYLSMVKTIHDSQSIDQILSALKKVLELTSKSNQPQKRYSDLVSEAITCIQE
                     EYSQELTLKAVSDRLHINGVYLGQRFKNETECSFSQYLNQVRIQKAQQLLLYTNKSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGSY"
     gene            complement(9476..11200)
                     /locus_tag="TV193_000428"
     CDS             complement(9476..11200)
                     /locus_tag="TV193_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1512662.1"
                     /translation="MTSKSLKRFLMEHIKQGFLINRLMKIYSLFIVALFSLSAVGLST
                     YSIRNTYQMVDNQMQMRLDETLARLQSQNYITLRVLEQLIGRPEDYRNLYQYMILTPN
                     QYLTKVFEDWGEGKNTPLFSEQVRRLFDLYPDLDGLTLMLDDSTSYLYADRSIKTGRL
                     LFGKPQTLKGNYLVRSIRHPESGDVTGRLYLHFASPSTMLQPEQHKYLATFAFDYYGR
                     ELFHQGGAAFPELEAGLKKALKADQAIDLTALSKSYHIQYNRSGDLLAYVAVKRSYFM
                     EEAVRTMLLYGLGSLLLAWLLLQLLFRVFRNYIRQVSEITDTIEMVAAGDLSLRIDNS
                     HMELELYHISEAINQMLGNINAYILEIYVLEVEQRDAQMRALSSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFAALLRNNISQDKVTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKLDPVVADVEIPKFIIQPLVENYFVHGIDYSRYDNALSIKALDEEDSILIQVLDN
                     GKGISPERLVAIEKGLEEPQSTGNSSIGLQNVYMRLFHKYRDRVTWSMSQAPTGGFRI
                     QIRIRKEA"
     gene            complement(11190..11795)
                     /locus_tag="TV193_000429"
     CDS             complement(11190..11795)
                     /locus_tag="TV193_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEL1512663.1"
                     /translation="MTGIEKACFLIWKMMQLTLIFHLLSLCGAVIFGVGPAWQTIVTL
                     FLETSQQEKHYSLKRAFQIWRRVFKEANLSFFFFGLLLLLLNTSLYLAIQFQSLLWFS
                     LSFIIMFVMVWLVMIVIYMTFYAVTYEIAFWENLKLSFISIFLNARQFLLTLVVLAGV
                     AWFTWQYKGLYLFLSFGALVLLLDMVTKPNRRMVDGVIDDK"
     gene            complement(12143..13588)
                     /locus_tag="TV193_000430"
     CDS             complement(12143..13588)
                     /locus_tag="TV193_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1512664.1"
                     /translation="MKKWQTILCVTGAVLAAASLTACGSKSASKDGEVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATLDLQYIGWGDWDDKMRIIIASGENYDIAFANNYVVN
                     AQKGAFADLTKLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNINSYADAEKVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDEPFKANLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSNVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKVGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESIT
                     DDMIAKRDQSIKDAKESPILGFTVDTKAIKTELSKISNVMNRYKASINTGTVDPDEAL
                     PKLLSDLKDAGWDKVQKEVQKQLDDFVTKNK"
     gene            complement(13672..14598)
                     /locus_tag="TV193_000431"
     CDS             complement(13672..14598)
                     /locus_tag="TV193_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1512665.1"
                     /translation="MEKKKTVKRVNVRTFDPKTNAVFNVLIALFAISCIIPFIFVMII
                     SFTDESYLINHGYSFFPAAWSTKAYHYIFQGAMSHRIIRSFAVSVFITVLGTFINTTM
                     TSTYAYAISRPYFPYRRFFTIYALITMLFAPGMVANYLVVSNLLQLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGAGELMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSESLYPMQYLLMKIQSNIQALAQNAGMSAQLSDSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            complement(14608..15558)
                     /locus_tag="TV193_000432"
     CDS             complement(14608..15558)
                     /locus_tag="TV193_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1512666.1"
                     /translation="MTTKISSKKSFWKNVIKYRALLLMVLPGFVWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLDNFKYLFASKDAWLITRNTIAYNLIFLLFNVFF
                     AIAFAIIMSELRNKKAVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLIDSG
                     NSPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRHITIPQLLPMMSILLIINIGSIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDISMASAASLYQSVVGTCILLITNAFVRRMDPDAALF"
     gene            15770..16663
                     /locus_tag="TV193_000433"
     CDS             15770..16663
                     /locus_tag="TV193_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1512667.1"
                     /translation="MTLLCIDIGGTSIKFAICHKGRLKKQSSRPTPQSLEDFYHMLDE
                     RLAYYRTEKLSGIAISSPGAVNKATGIIEGASALPYIHGFPIQQCLEERLGLPVSIEN
                     DANCAALAESALGAGQGTSSLAMLVLGTGVGGSLVINGRIHYGAHLFGGEFGFMVMNE
                     RYQTFSELGTVVNMAKRYSQIINDGKSYTGKEVLELADQGDPVALKERQVFLQSLAMG
                     VFNIQHAFDPEMILIGGGVSQADFLLPALEAELDKLYQIVSISDLRPQLAICHFKNEA
                     NLLGASIDFMQEHRKDEMWID"
     gene            16651..18825
                     /locus_tag="TV193_000434"
     CDS             16651..18825
                     /locus_tag="TV193_000434"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEL1512668.1"
                     /translation="MDRLDFIDTRFGTTNHYHFSQGNCLPLTGVPFGMHYLSVETSQD
                     RGAWWFHPDDHSFSGIRLTHQPSPWVGDFATVTFLPVSGPLTKGDVFHNQTSYRPKEA
                     AFRPHLLEIFSQRHRILTRATAAAYSFHCDFSFDNGKAGLIIHNPGKSSWQVTADGKT
                     ILGCVQNITDCQDKDLAMFVYLQFSSPVLKKLIGEDLNSKSLDDCSKTSFTYLQFADD
                     LKHLELRAAASFISFDQAQLNWQRDFPRSFEKSLEYSRKEWLSYLSRIDIKDKDFDKV
                     KAYYQHFYRALLFPQRWYEITATGQAIHYNTTSQRPVAGKYYTNNGFWDTYKSVYPLL
                     SLIAPEIYADILEGLLSAYQDTNYLPKWLSPDERGLMPGTLVDAVIADGAVKGIRKDL
                     MPELLEAMLATANTDSQGTGYGRKGNQDYQELGYLPNSYQESVNQTQDYAYSDFCIGQ
                     VAALLGKTALSDQYHTRSLNYRHLVDTDTGYLKSKDRQGQWQCGFNPIHWGQDYTEGS
                     YYQNGFAFYHDILGYIRLIGGNAAIAKRLEELCNHEPVFDVHSYGFEIHEMSELAAQD
                     FGQIAISNQPSFHLPYLYHYIGQPQYSQLILKNLLSHAFTDTGYPGDEDNGSMSAWYL
                     LNSLGLYPVTPGTGQYLIGIPTVDQATLYLPNGNTIQISCRGNVPQYQFVKEVKLNQA
                     SYNKLYINHDDLIQGCQLDFQLGLVPPLKHYSAEDLPYSLTR"
     gene            complement(19021..19158)
                     /locus_tag="TV193_000435"
     CDS             complement(19021..19158)
                     /locus_tag="TV193_000435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512669.1"
                     /translation="MELAKKRRKTQKPAQSPLKLGLEKLREILQEQLVALAVLPARVM
                     G"
     gene            complement(19145..20536)
                     /locus_tag="TV193_000436"
     CDS             complement(19145..20536)
                     /locus_tag="TV193_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1512670.1"
                     /translation="MLEFPEGFWWGSATSGPQSEGCFQKPHRNLFDYWYEQNPELFYD
                     YVGPDTASDFFHQYDQDLALLASLGHNSYRTSIQWTRLIDDFETATINPDGLAYYNRV
                     IDACLAHGMRPVINLHHFDLPIALYQKYGGWESKHVVDLFVAFARVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLLQFHYPAIVDGKKAVQVAYNLALATAKVICTYQEQAAELSNGS
                     VGTILNLTPIYPATDSEADLAAAHVAELWHNDLFMSAAVYGSFPKELVAILQRDGVLW
                     QSTPEELDLMAAYTVDYVGINFYRPKRVKAPEVIPVISPSWSPEWYYDAYLMPQRRMN
                     VDKGWEIYPEAVYDIALKMRDQYRNIPWFLSENGVGISGEDRYRDESGQIQDDYRIQF
                     LKEHLTYLHKGIQAGSNCFGYHVWTPINCWSWLNAYKNRYGLVENNHRTQRRRVKKSG
                     YWFKEVAEANGIS"
     gene            complement(20563..22257)
                     /locus_tag="TV193_000437"
     CDS             complement(20563..22257)
                     /locus_tag="TV193_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HEL1512671.1"
                     /translation="MSIYQALKDYQEVITRGDYLVFDAPVSCRFVGRFFRFENQTAMK
                     PSLTASVYVNWVEEGAADLTLKHVFNRTLARDAFTLTISEDKELVIESQNLRGFRYAQ
                     EALEKVMTVKEGRLYLPIVSVRHSPSFAMRGVIEGFYGTPWTREERLDCLSFIADKGM
                     NTYMYAPKNDDYQRSHWREPYPEDWVAHFRDLIQLAKERQVDFWYMISPGLDFDYTKE
                     EDYQLLYQKLQQLLDLGVCHFGLLLDDIDYQIVAAVERRFKKTAYAQAHLATAVYQFL
                     QRQHAAPDLVVCPTEYDNHHDSLYLAELSEAIPAEVAFFWTGPSTLASQISQADIETI
                     AAIYRRPIIIWDNIPVNDYQDDSKRLFLTPFANRSPFLCQPDYQVRGIVSNPMISWEL
                     SKPTLIDMSRYLWDAKRYQPSYSWLEALRDYTGDKAMALALLRFAWHNGNRHLHRDLP
                     FEVEEALMRKDIASLSGWVAELVELVDKLKELDIPAFQQAIAPWFDRAKADQSFWRVI
                     LEQAPDLEQQYAELQEQRHRIGSNIPSRFYQLHYLQENSMLGNQAQVAEARAEDYT"
     gene            complement(22272..23330)
                     /locus_tag="TV193_000438"
     CDS             complement(22272..23330)
                     /locus_tag="TV193_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1512672.1"
                     /translation="MTELLYKKIYHFIKEQIDSGQLQAGDRLPTEKALSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVTDGPPPSTQPNKDILLILPFASDYELGDYAKGIM
                     TVVADKGYRLMVQLTSTVSLEELADYAGVIYYPEDVNHSIELLFYCAQRGLALVLLDK
                     ALDLFDFPAVVADNKGGAYELTKHLIDQDCRRIMFVATASFGEVSSVRDRYLGYLAAM
                     AETELEANYFVKLKSESNAAYLERLVDELTAATAEKTGLVVENDWLAIQLIQKILQVG
                     LSIPDQVAVVGFDNSQASQLISPQLTTAAQDFYQMGQQAAQLLIERLTRPDQQTASCQ
                     LPVKVFIRESSQKSLEML"
     gene            23463..24749
                     /locus_tag="TV193_000439"
     CDS             23463..24749
                     /locus_tag="TV193_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEL1512673.1"
                     /translation="MTRPIPSSVLRFMDTIEELCGEEHRSWAINFKASFANTLETTLK
                     IDEDGTSFLLTGDIPAMWLRDSTAQLKPYLFLAKTDAGMRQIIAGLVKRQFRYICIDP
                     YANAFNEEENSKGHQADHTQMGPWIWERKYEIDSLCYPIQLAYLLYRETDCTEHFNED
                     FHRGIKLILDVWSTEQDHTASPYSFERDTWRKEDTLTHNGKGAPVAYTGMTWSGFRPS
                     DDACQYGYLVPSNMFAAVVLSYLEGLYTDLFKDQTIARRAHALRLAIQKGIEEHALVT
                     NSQGEIIYAYEVDGLGHYTIMDDANIPSLLAAPYLGFCAKDDPIYLATRQTILSPENP
                     YYYQGSAASGIGSSHTPPNYIWHIALALQGLTALDQKDKADILDLLVATDAGTHLMHE
                     GFDVNDPSHYTREWFSWANMMFCELLLDYLGFTISP"
     gene            24764..27490
                     /locus_tag="TV193_000440"
     CDS             24764..27490
                     /locus_tag="TV193_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEL1512674.1"
                     /translation="MTPKKVHIISHSHWDREWYMAYEQHHMRLIQLIDDLLDLFKTDP
                     DFHSFHLDGQTIILDDYLQVKPGREAEIRQAIQAGKLRIGPFYILQDAFLTSSESNVR
                     NMLVGKEDCEQWGASVPLGYFPDTFGNMGQTPQLMRKAGLNAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEMIWQGPDDSRILGLLFANWYSNGNEIPTEEKKARQFWDQKLADAER
                     FASTRHLLMMNGVDHQPVQLDVTKAIALANKLYPDYDFVHSCFEDYLADLSQELPEEL
                     SIVSGEMTSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLATMAFEVTGTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHQEMMPRFDKAYEVGTYLAERSANQIAEAI
                     DTSMFPEDSCPFVLFNTCGHEKKTVSDLTLTWKIFPFGQRLPKAVYQEAKEYLETRQP
                     QFQVIDAAGRIIEEAEILGTDIAFDYALPERTFREAYFAIKVQLRLPLTLSAMSWQCL
                     ALKETDQPCQATDTDKMLFHQDRSCLENDFLKVIIAANGLLTIEDKLNGNRFDSCLQY
                     EDCGDIGNEYIFRQPDHDSPYLAHQGSCKLRVLTNTAYLAEIELTQTFDIPLATDDRL
                     KAEMEAVIDIRERQAKRSQEKAPFTVTTVIRMEKDSPRLQFQTSFNNQMTNHRLRVLF
                     PTHLKTDHHFADSIFETVKRPNHTNAQFWKNPTNPQHQEAFVSLFDGRTGVTVGNYGL
                     NEYEILPDTNTIAITLLRSVGELGDWGYFPTPDAQCLGQQTVSFSFESINATTRFASY
                     WRAQEAQVPVTMAQTKRHSGQLPAQYAYIKGATDHVALTAFKRRLSDNALITRSYNVS
                     NDKACALTLAIPDHTARVTSLLEEDQHEPLPAELGKGEILTLAWKKSESAHL"
     gene            complement(27679..28287)
                     /locus_tag="TV193_000441"
     CDS             complement(27679..28287)
                     /locus_tag="TV193_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1512675.1"
                     /translation="MIEIKQLSKHYGKKTIYDKLSLTFEANRSYALVGPSGSGKTTLL
                     NAIARLEKPDSGQILVNGQDIWSMKEQDYFKDYLGYVFQNYALIEEETVYDNLKMLAP
                     KSNIVEALHSVGLDSSFLSQNIYELSGGQAQRVAIARLLLKKACIILADEPTGALDKE
                     TGDEIIELLLSLVSPDTVLIFATHDPNVFSRVDDIIDICHLQ"
     gene            complement(28284..30287)
                     /locus_tag="TV193_000442"
     CDS             complement(28284..30287)
                     /locus_tag="TV193_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1512676.1"
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASN
                     KDVDKGHVLDRIEALAEQEHIQIYRPYLDHTGKEATYLFGTNGKKTVYSSNRKELLTN
                     DLSGMYYTTRSLPSSFETAMTERGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVF
                     ALLLFAVKLMYAKKSMILRSLGLFEHYSRKELLQDLLLMGASFAVSILLFILYQGSIS
                     NVFVKSFTLLILTNAVILLLLMLAVHALFFINIRSLKALAILKNKQATPLVLFVWLVG
                     ICLSSVIFGLSLHKSLETIGKSANDIQVLGKWDKAKDFAEITWLDTLSTHTDDNHQID
                     SDYFKEENQRYQHFLLSFSDNDVIYSALSSLNETNLQSAPDDFKKELKTNGVDPRIAS
                     KVRYVNQGFMLKNKDIFPNNDYGRPAADAVGVIYISKHMMGDADSILNIVNYEWFQYS
                     SLKANQLVVQEVPDGQKSFLFNHKQDQQDIFAQQEEVNTILVQLNFSFMTEPSLLTKF
                     GEMAQKSIYRQALIRDRLTQAGLTNFSSLTNVSNHLILERHKILSQLIGSVIALTVLA
                     IAQCFIIYEYIVSLMKQKAKKISVWFLMGQKSLVLIGRLLLPLALCLFLAIGMMGILT
                     GNRLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
     gene            complement(30356..30682)
                     /locus_tag="TV193_000443"
                     /pseudo
     CDS             complement(30356..30682)
                     /locus_tag="TV193_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin, lactococcin 972 family protein"
     gene            complement(31092..31673)
                     /locus_tag="TV193_000444"
     CDS             complement(31092..31673)
                     /locus_tag="TV193_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEL1512677.1"
                     /translation="MRRIRLATLADAKALLDIYRPYVEETAVTFEYTVPSLTEFERRL
                     SDIMVFYPCLVVEEEGGILGYAYASRFHARAAYAWSAEVTIYLAQEARGRGLGSALYH
                     RLEGYLKGMGILNCNACIASTAHATPYLTNSSQVFHEKLGYRLVGRFHQSGYKFNQWF
                     DMIWMEKLLGEHDVRPRPVMSFRDFLCQKHQSE"
     gene            complement(31933..32346)
                     /locus_tag="TV193_000445"
     CDS             complement(31933..32346)
                     /locus_tag="TV193_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1512678.1"
                     /translation="MLNKMKRLHYLMIFRLLTGQLPAISLMAVLLSKDIHRLSLGSLI
                     SFAIFAVSTAASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSS
                     SEFYKQVIAVICSFISFVTMGLMIWGIRYAKAYRR"
BASE COUNT         9570 a         7673 c         6667 g         8835 t
ORIGIN      
        1 tataggtaaa ccttttcttt ttgtatttga aaagctaaac tctcccacaa taaaagctat
       61 aactagcctc atcatgatac tcaatcatca gcacttcccc accatgcttg cctattccag
      121 ctaataagca ttctcaacag ctctaatagc cataaaatct ctaccttaga gggctaggat
      181 tctcaaaagc ttctcctttg tcaacgagct ggtcactctc tttattagct tgaaatttaa
      241 gcttgattat ggtatgattt cccaagctat gaatagttct gtcatgcctt attcacagta
      301 ttatctaaga cagagctgtc atcttacctt tggggaatca ttctctcaat atcatattag
      361 gaaagagtat aaatgggaaa cgatataata gctgattttt taaacaaggg ctgtcaaaag
      421 agtaacttta ttgttggtcc ctgtgccatt gaatcttatc agcaaatcag acaggcagca
      481 gcaagtgcca aggctttagg ctacaggtat tttcgagggg gagcctataa gcctagaacc
      541 tcttctaact cctttcaggg cttagggctg acaggggtta cctatctaca tgaggtttgc
      601 caggaatttt cgctgaaggc tgttagtgag attatgtctg aaaggcagct agaggaagcc
      661 tatgactatt tagatattat tcagattggc gctcgaaata tgcaaaattt tgaactgtta
      721 aaggtattgt caaagattga caagcctatc ttgtttaaac gaggactaat ggcaaccatt
      781 gaggaatatt tgggtgcttt atcttattta caagaaaatg gcaagcaaaa tattatttta
      841 tgcgagcgtg gggttcgtgg ctatgatgtg gaaactagaa atatgctaga catcatggca
      901 gtccctatta ttcagcaaaa ggtgaagctg ccaatcattg ttgatgtctc tcactcaaca
      961 ggaagaagag atttactatt gcctgcggct aaggccgcta aggctatcgg tgccaatggt
     1021 attatgatgg aggtgcaccc tacacctgat cttgccttgt cagatgccgc gcagcagatt
     1081 gattatcaac agctagagca gcttggaaaa gagctttggg aaagctaact aacagcagcc
     1141 acaggtccag tcatttgaac taatggtgct taggagagaa agacgcatga cacaaacact
     1201 tcaggttaag tctcgtatca atgactatcc gattatcttt acagacgata tttttcagcc
     1261 gctgaatcaa tttcttgctg aaaaaggaga cgtcaagcta ttatttatca ctgatcaaac
     1321 ggtatttgat ttataccagc ctttatttag acgttttcaa caggattacg atagttacct
     1381 tcatattgct gctccagggg ggcaatctaa gtctctagag gaggttagtc ggatttacga
     1441 tcgactgatt agggctaatt tttctaaaaa ggacgtcatt gttactgttg gaggaggggt
     1501 gattggagat cttgggggat ttgttgcggc aaccttttac cgcgggattt cctacgttca
     1561 gattccaaca accttactta gtcaggtaga cagcagcatt ggtggtaagg ttggggttca
     1621 ctttaagggc ttgaccaata tgataggcag tatctaccct ccaaaccaga ttatcgtgtc
     1681 agccaagttt ttagacacgc tttctgaaag agaatttgcc tgcggcatca gcgaaatgat
     1741 taaaattggt tttattcatg atcgcaagct ctttcaacag ctcctagcct tccccaagga
     1801 ccgcaatcaa gagcagctca ggcaaatgat ttttcaagcg atttgccata aaaaaagagt
     1861 ggttgaaaag gatgaatttg aaggcaatct ccgcatgtcc ttaaatttcg ggcatacgct
     1921 agggcatgcg attgaagcct tatgccatca cgagctttac aggcatggtg aggctattgc
     1981 gattggcatg gtctttgagg ccaagctggc cgtccagcag cagctattga gccaacagga
     2041 tttagaggca ttacaggctg cctttgaggc ttatcagcta cctaccacac ttgaggctaa
     2101 gtcaatgaca gccgaagcct tgatgactgt tttaaaaaca gataagaaaa attctggtca
     2161 gcatattgtc ctcattttgc caacgacaaa aggctatgta agctttccta ttgctaagca
     2221 tgacagtcgc ctgctggatt ggctaagaag cctgctagat atcgcctgag aaggcttttc
     2281 tcctgtctta ttagtcgagt gaaaaaactg ctgcttctga aaaacaaaaa ggcttcaaag
     2341 cctcttgttt actgagtctt ttgatgagaa aagaccactt ttttcacagt aaggtgaaag
     2401 gcctaagctt cattgctttg tccctaggtg aatgctaagg cataggtata agaagcatag
     2461 gctactctaa acattatatt gacatgcaga ggtgagctgt ctgcatgaca cctaaaaagc
     2521 accttgagct gaactgatct cccaggcgtt agagccttaa tctaaccttt tggaggcact
     2581 tcatagctct tggtgctttt ttaattatcc ttaaataatc gtaaggccaa ctctaaggca
     2641 ataaaggcaa tgttatcctt ggcttctagg tctgcttcat tggctaagct tcttgcgtcc
     2701 cattcatcag catctagatt atcagcggaa taaaaaaact gaaaatgctc tagctgtctg
     2761 aaagctgcta gggcagcaat cgcagagcat tccatgtcaa cacaaatagc cccttcctgc
     2821 tttcgttgaa tcatcttgtc tctggtttct ctataaatgc catctgttgt ccaggtctta
     2881 ccaagggtat aggtctggga atgctgttct aaaacatcaa tagcccttgt taaataagct
     2941 tgattcactg caatgtcatg actagcaggc tgatagtggt agctggtccc ttcgtctcga
     3001 atagcactag ttggaataat aatagagttt tcactgatag tagcgtctaa gactccacag
     3061 gtcccaaaaa ccaagagctg cttcattccc atagcaatga tatcctctaa aaccccaacg
     3121 cagccagctg ctccaacgta ggaattgaaa aagccaagct tatgcccttt aacatctaat
     3181 tcgtatattg gaatatcaag attagcaacg cttgttgtgg ctatcagtcg atgtggcagt
     3241 gcattaagta ccctattaaa ggttgctctt gcaaagcagg tgactactgt tttaggaaag
     3301 tcatctattt ctgctacaag gtccttaggg ttaatgatag cttggtagtc agggtcaaat
     3361 tgtgtcaata tcataggctg ctcctttgct tttggtgctt tttattataa ataaaatgcc
     3421 gacaaacctc aagaccaatc aaagagctga gcaattaacc tttttttctt tttcctatac
     3481 cggcgtgagc agcaggcgtt cattccttgt tctgacataa aagctctcgg atataggcta
     3541 ccggcatgtc ttcacctgtc atcagcttaa aggcttctgc tccttggtaa aggagcatgc
     3601 ctaggccatt catcactttt ttagccccat gctcacgcgc aaaggctaag agctttgttt
     3661 ctgccgggtg ataaacaagg tcaaaaacca caagatctgg gcgaataaga gctggatcag
     3721 taatcaggcg atgctcctca aaaggcttca tgcctacacc agtcgcgtca atataaatgc
     3781 tagactctga aatagaccgc ctaaaggctc gatcatccgc taaatcctga aggcttgcca
     3841 gggctgaggt ttgggtatta attctagcaa ccagctgctt ggcctgctta aaggtagctg
     3901 ttttccgatt aaatagtcga atctccttgg cgccatcaag tcccagttga acagcaatgg
     3961 ctgtgcctgc accgcctgca ccggcaatcg taatgatctg atcctttatc gagacccctt
     4021 cttctgctaa ggctcgaata gcacctgtgc catcggtgat atgaccaaca agatgacctc
     4081 tgccatcttt attaacaacc gtattaacag ctccagctaa ggctgcagcc ggtgatagct
     4141 catcaagcaa tgggacaatg gcctgcttat ttggcatgga cacatttgca ccgcaaatac
     4201 ccaaggcacg catgccctga acagcagcag ctagctcagc attaccaacc tcaaaggcta
     4261 ggtaggcata atccagcccc agcttagcat aagctgcatt gtgcattttc ggtgataggc
     4321 tgtgacgtgc cggtgctgcc agcaaagctg ttaatcgtgt ctgacctgat aaacgctcta
     4381 gcatcaaata cctcctcctt tacatcatat caggcgatgc ttattttttg ctaacctagc
     4441 aaagcttgct aggcatttac tgtcattata ccttattttt caaagactgt ctcagctcaa
     4501 tcctattgac agtatgagcc gataagcttg aagcctaagc ctcctcaacc atgctccaaa
     4561 ggcctagctg aagcctagct aagtcaaaag cctgtctgat cggctgctct aatgttaggt
     4621 ccaggcttag cacatcaact acttcttcca gcatgatgta gtgacagggc tgttctatct
     4681 gatcaagcga taggatcagc tgttttgatg gcgcattggt gctgctgcga tagtccaaaa
     4741 caagcctaag cgagcttaag ggcttcttta gtcctgtcag gctaatggca ccaatggcct
     4801 gtatggtatc gtattgatag cggtagctaa gctgggtatc actctgaaac agccgcttct
     4861 ttttagcaac taagctaagc tcttgattga tccttaatcc ttttgtatct gacttaagga
     4921 tagcttcaag ctccaaagcc tctccaaaac aaagggtctg cccactaacc cttgactcct
     4981 cagaaaaaac tgcctctgtt agctgccaat caataggaaa agccttggta aataactggc
     5041 cagcagctgc cctaggctgc agccagtctg gtagaatgat atcattgccc tttagcagcc
     5101 ttttgatcag tggctgaaag gtcagtggcc ttgataatgc tgttgtatag ctaaaaacca
     5161 ttacagaatt atcaggcaga taatggcctt gccgctttaa gcagctatca ggattaggca
     5221 ttaagctatc aacagctgat cctcttgacc ttgcataggg cttgctaggc ttatttgtct
     5281 cattagtgat aaagctgtat ttatcaagct gataggctaa aagcttctca ttaacggctg
     5341 cttcagaaac cgtcaactga tagctggctt ccacgaatcc tgcggctcta gctgttattc
     5401 taagctgacc cgcacgacca tcaagagcaa taatggctaa tagcttgcca ccatatgctc
     5461 ggcgtgacaa ggcagtatag ggcctatggt cacgaggatc gccattatcc agagcaaggc
     5521 aggctccagg accctcaacc tcaagcttaa tcacaggatt agcactgagc accaaggtct
     5581 cattagcatc taacaaagac aattcaagat aaagtagcgc aggctctgca agcagtttag
     5641 gaggctcaaa gcaggaccag gaaagctgag caggctgctg gtagctgctc acacaggaac
     5701 gaccgctggt ctgtgtgagc acctgtccct tgtcgtcata agcaatagct ctcaagctgc
     5761 ctgagcgata aggaagcttc catgtcaggt aaaggttttg atgaggtaat tctgctgcat
     5821 cgtcaccctc atatagctgg tagcaatggc ctgctggtgt ttcatgcctt gtcagggtct
     5881 tgatgccata atcaatctgg cccccatgac catcatcaaa aagtattctc acactagcag
     5941 cattactata aaccacaacc tccaccatgc cctgatcatc tagctgaagg tctttttcct
     6001 gccagctggg caggatatga agtgtcgttt tgtcttttga ccattggctt tggtagaaat
     6061 aatagctatc cttagcaaat ccagcagtat ctaaaatacc aaagtaggat tgcttgggcg
     6121 acggccactg atcagctgcg cctgagtcaa tcttgttcca aggagtaggc tcccctagat
     6181 aatcaaagcc cgtccaaaca cactcacctg caacaaaatc ccttgtgatt gtatcatacc
     6241 aagcctcact agctaaggat ccccagtcaa ccgttgactg gtcataggag gttagctcat
     6301 gatcctgact agctcctccc ttgagatgat agacccctct actattaata gcagaggctg
     6361 tctctgagcc ataaagcagc caagtcgggt tgtccctatg caatcgatca taatctctgg
     6421 ccttagcata gttaagtcca atcactcctt gcacggactg gagctgattg acctgctctg
     6481 ccaacgcttt tgtttcctgc gcccaatgaa aatgcttgtc cttgagctta ttatccccaa
     6541 gggtaatagg tcttgactga tccagctcag tgatccactg gcatagctcc ttagcaacat
     6601 aagggtagtg gctcacatca gctgagaagc cttctaacaa ttcattgccg attgaccaca
     6661 tcaagacaga tggatcatga agacctgaga gaaccatggc ctgtatgcta tattgcgccc
     6721 aggtggtttc tgctgtagtg actcccttta gcctggctgc attttggtgt cccactgtct
     6781 tgtgaaaatg gcttgaaaaa tcatggctat taccgttttt agcataagtc caggtatcaa
     6841 aggcttcctc aatgagaaat aacccaagcc tgttagccag atccttaagc cttctggcac
     6901 tagggttgtg cgtgacacga accgtatttg ctcccatttc ctttagcaaa acaagctgcc
     6961 tagctatagc ttcctcataa gcacatgccc ccaggctacc ctgatcatga tgaagacaga
     7021 ccccttgcag cttaaaggct ttgccattca aaaagaaacc acactcagca tcaaaatgca
     7081 gctgtcgaaa gcctgtttca agtgtcagcc gatcaagcac tgctccctta tggtaaagaa
     7141 gcatatcaag ctgatagagc tggggctgag ctggcgacca cagtttgata tgcctaagag
     7201 gaatggtcat caccagccta cctgactcct ccaagaggtc caaggctacc ggtttactct
     7261 catatactgt ctgtctctgc tggatatctg ccagctgctc aaacagacta aggctaagct
     7321 gatagccact caaggggacc tgttggctga gtccaagctc tatctcaagc gcttggctat
     7381 cagcctcaag cgctgcctgg gataaggata aacgaagccg atccttatca agatgaacct
     7441 tcggaagaac ggtcaaaaaa gcctcccgat aaagcccact tccagaatac caacgcgagc
     7501 taggcaccag atgttcaacc cgaaccgcta atagattctc ttgcccaggg attacaaagg
     7561 ctgagagatc atagctaaag gcctgatagc cattgacatg ctctcctatc aaatgcccat
     7621 taaggtatac ctgcgtttcc atataagccc catcaaaggt cacatagacc ttatggtcag
     7681 ccagctttgg atcaagggca aaatacttcc ggtaccagcc tacaccacct agcttatagg
     7741 cactttgagc ttcgccatta accgtatagg gctgattaat gctaaaatca tgtggtaaag
     7801 ctatctgctg ccagtccgaa tcatcaaaaa atggctcctg agcgagctgc aaatcagcca
     7861 tcagaaagcg ccaccccttt gaaaaggcat ggcagcgccc tactttatca atccagtgaa
     7921 gctgatagat atccccatga gattgatccg ttgaaccagt gattgtctct acagacatag
     7981 cgcccccttt cttaatagct tccttttata gcttgataat tatctttata acggtctcta
     8041 aactccttgg gcgataaacc atttaatttt ttgaacattt ttatgaaata atggttagta
     8101 ttatagcctg tctcataggc aatttcgtta atcgatttat tggtgtaaag cagcaattgc
     8161 tgtgcctttt ggatcctcac ctgattgagg tattgggaaa aactacactc tgtttcattt
     8221 ttaaagcgtt gtcccaaata aaccccattg atatgcaagc gatctgacac agccttgagg
     8281 gttaattcct gagagtattc ctcctgaata caggtaatgg cttcactgac cagatcagaa
     8341 tagcgctttt ggggctgatt gcttttgctt gtcagctcaa gcaccttttt taaggctgat
     8401 aagatctgat caatggactg actatcgtga atagtcttga ccatcgatag gtaggtcgtt
     8461 cgatctaaaa tcggaaattg gcgataaatg tctgaaaata agagaaaaga gacgtgcttg
     8521 acgtcctcag gagagaagct tagctctgtc atctcctcaa agattgcctg taatttggag
     8581 acaatagttg gctcgtcccc aatcatcaag gtcttgttaa aggaaaaaaa ctgcaatcgc
     8641 gattccggca gctcaatttt agcgttggtc ttagcagcta cctgagacac ctcgctgttg
     8701 taaaaaaagc tccttctgac ctgattatag ctttcataca cattttccca atcaacaacc
     8761 gtttctccta gaatgatctg attgatggta ttgtaaaatc gctcctgaag cgtattagta
     8821 aagcgcttag cctgatggct ctgtcctaat agaatgacta gatagacctt cttttgctct
     8881 gcctttttta agtaaaaggg ctgcttggag gcctcaaaaa aggcttctaa ggcagggcta
     8941 aaagtcttgc aatccacata caacaccgta aagcctaaaa gctcagcctc gggttgctcc
     9001 tgcgttagtt gaaaaaactc tttctcactc aattcatcag caagccagag atttatcaag
     9061 ccctcacgat aagcagcctg acgcaaagaa gctgccctct gctcatcaag ccattcctta
     9121 aaatagagca ttttagctac cagctctttt ttatcaactg gctttaggag gtagccctta
     9181 gtctctagct ccatagccct ttgcacatag gaaaattcct gatagcctga taaaatcaag
     9241 gtctgcaaat gcggcaatac atctcttgct gcctcaatca attccaggcc tgtcatacca
     9301 ggcatattga catctgaaat catgacatct acagcgcagt catctaggta agctaaggct
     9361 tctttggctg accttgccgt tgccacaacc tcaaagccaa gcgcctgcca gtcaataatc
     9421 acctttaggc cctgtaaaat catgtattcg tcatcaacta ataagacctt gtacattaag
     9481 cttcctttct aattctgatc tgaatcctaa agccaccagt cggtgcctga gacatggacc
     9541 aagtcactct gtctcgatat ttgtgaaata ggcgcatata gacattttgc agcccaatag
     9601 agctattccc cgtcgattgc ggctcctcta agcccttttc aatagccact aagcgctcag
     9661 ggctaatacc cttgccatta tcaagcacct gaatcaaaat actgtcctcc tcatctagcg
     9721 ccttgatgct aagggcgtta tcatagcggc tgtaatcaat cccatgcaca aaataatttt
     9781 ccaccaaggg ctgaatgata aacttaggaa tttccacatc agccacgaca ggatcaagct
     9841 tgacatggta ggcaaagcta tctggatagc gcatttgata cagatagatg tacttttcac
     9901 aaaaagccag ctcttctttt agagtggtta ccttatcctg gctgatgtta tttcgaagta
     9961 aagcggcaaa ggcataaatc acatctgcca attcctcctg ctgacagcta agcgcataca
    10021 tgcgaatata ttctagggtg ttatacaaaa aatgaggatt gatttgtgat gacaaggcac
    10081 gcatctgggc atctctttgc tcaacctcaa ggacatagat ttctaaaatg taggcattga
    10141 tgttgccaag catttgattg atcgcctcag aaatgtgata cagctctaat tccatatgac
    10201 tgttgtcaat ccttaacgac aaatcaccag ctgcaaccat ttcaatagta tctgtaatct
    10261 cagagacctg tcggatataa ttgcgaaata ccctgaaaag gagctgtagc aataaccaag
    10321 ctagcaataa cgagccaagg ccatacagga gcattgtacg cacagcctct tccataaaat
    10381 aagacctttt gaccgccaca taggccagca agtctcccga gcgattgtac tgaatatgat
    10441 agctcttgct gagagctgtc aaatcaatag cctgatccgc ctttagcgcc tttttaagac
    10501 ctgcttcaag ctccggaaag gcagcgcctc cctgatgaaa gagctctctg ccatagtaat
    10561 caaaggcaaa ggtcgctaga tacttatgct gctcaggctg tagcatcgtg ctggggcttg
    10621 caaagtgcag atagaggcgg cctgtaacat cacctgactc agggtggcga atggacctta
    10681 ctaagtaatt gccctttagc gtctgaggct taccaaataa gagccggccg gtcttaatcg
    10741 acctatctgc atacaaatag gacgtgctat cgtccagcat cagggtcagc ccatctaaat
    10801 ctggatacaa atcaaaaagc cttctgacct gctctgaaaa cagaggtgtg tttttgccct
    10861 caccccaatc ctcaaaaacc ttagtaagat attgattagg ggtcaatatc atgtactgat
    10921 acagatttcg ataatcctct ggacgcccga tcagctgctc cagcacgcgc agggtaatat
    10981 agttttgaga ttgtagcctt gctagggtct catctagccg catttgcatt tgattgtcaa
    11041 ccatttggta ggtatttcga atcgaatagg tgcttagacc aaccgcactt aagctaaaga
    11101 gagccacgat aaacaggcta tatattttca tcaagcggtt aattaaaaag ccctgcttaa
    11161 tatgctccat caagaaccgc tttaaagatt tacttgtcat caatgactcc atctaccatg
    11221 cgacgattag gcttggtgac catatccagc aacaaaacca gcgcaccaaa gctcagaaaa
    11281 agatacaagc ccttatactg ccaagtaaac caagcaactc cagctaaaac cacaagggtc
    11341 aacaaaaact gcctggcatt caagaaaata ctgataaaag acagcttgag attctcccaa
    11401 aaagcaattt cataggtcac tgcataaaag gtcatgtaaa tcacaatcat caccagccaa
    11461 accatgacaa acatgataat aaaggatagg ctaaaccaca gcagcgattg aaattgaatg
    11521 gccaagtaca ggctcgtatt cagcaataat agcaataatc caaagaagaa aaagctgaga
    11581 ttggcctctt tgaagacccg acgccatatc tgaaaggccc gcttgagcga ataatgtttc
    11641 tcctgctgac tggtctccaa aaacaaggta acaatggtct gccaagctgg ccccactcca
    11701 aaaatcacag caccacataa ggaaagcaaa tgaaatataa gggttagctg catcattttc
    11761 cagatgagaa agcaggcttt ttcaattcct gtcataagat tatccttttc tagtatcctt
    11821 tgtaggacca atagcgccct aagagaagca acgatccctc agccagatga ctaaggtctt
    11881 agctgtcatg atgataagat gagatacttc taatatagca tattttactc taattgtgac
    11941 aaaagcttaa taaaaagagg acagccgact aaggctggta aaaccttgtc agcaagggct
    12001 ttggtggacc aactgccttg caagcaggct ctggcttttt tctaagagag gccttatctg
    12061 tcagctcttg tatgcctgct tgagctaaaa agaactgagg ctgtccccag ttcttaccac
    12121 cttgcaagga aagtccattg ccttatttat tttttgtaac aaagtcgtcc aattgctttt
    12181 gcacttcctt ttgaaccttg tcccaaccag cgtccttaag gtctgaaaga agttttggaa
    12241 gagcttcatc agggtctact gtaccagtat tgatactagc tttataacgg ttcatcacgt
    12301 ttgagatttt tgatagctcc gttttgattg ccttggtatc taccgtaaag cctaggatcg
    12361 gagactcttt agcgtctttg attgattggt cacgctttgc aatcatatca tctgtgatcg
    12421 attcttgggt gtagaggatc ttgttgttac cagtgttcca agcacccatg tgcattttgg
    12481 gttggtagcc atcaagcagc ttgattttct tgtcgccaac cttttcccag gccttgcctt
    12541 caacaccata aacaagacca tttagcaatt ctgggtcgct gttaagaagg gaaagaactt
    12601 caacggcctt ttctttattt ttagacacat ttgacacgac aaagttagcc atttgggctt
    12661 gtgaggtcgt tttaagaggc tttgtcaatg gtcgtgacac aatgtcttta ccagcagcat
    12721 tggtcaagat ggtatcgcca tagtccatag gaccttgggt ttcttcacgc atgaaccagg
    12781 tattgccttc aagcgggtag ccttctgtgt tggttgctgc atctgttgga atcaagcctt
    12841 ccttatacca tttatgcatc aagcgtaggt ttgctttaaa gggctcatct tcgtactgat
    12901 taatgatggt tggtttgcct tcatcgattt taacagcaaa tggttgattt ttggtcaatg
    12961 ggtaatcgta gtcacctgac atgctaaaga cttgaccaat cgcaaaggca gcagtattag
    13021 gttctttttc gtggaattgt ttcaagacct tttcagcatc tgcataggaa ttgatgtttg
    13081 aaatgtcaag gccatatttg tctaccaatt ctttgttgaa agacagcatt tgctgagcat
    13141 agacgttagc atctactgga aaggcataaa gcttaccgtc aatggtattt cctttaatgt
    13201 aggccggatc taggttctta taggttttct tggcgtattt tggcattagc ttagtcaaat
    13261 cagcaaaggc acccttttga gcattgacca cataattgtt ggcaaaggca atgtcgtaat
    13321 tttcacctga cgcaataatg atcctcatct tgtcgtccca atcaccccag ccaatgtatt
    13381 gcaaatcaag ggttgcccct gttttttcct taatacgttt atttgcaatt gtcatcagct
    13441 catcaaagtt atcaggctta tctcccacct gatacatcaa tagcttcacc tcaccgtcct
    13501 tagaagctga tttgcttcca caggctgtca agctagcagc tgcaagcaca gctcccgtca
    13561 cacataagat tgtttgccac tttttcatca gtaagcctcc taaaataatt tctttttttg
    13621 ataacagaat cattggaacg gtcagctgta tgacctattc caaatgggtg attattcctt
    13681 aaccccgccg atggttagtc ctccaacaaa gtatttttga aagaaaggat aggttagggc
    13741 gatcggcaaa gttgcaatga caacaatagc catgcggaca gattcctttg gtaaagaggc
    13801 taagctatca gatagctggg cgctcatgcc agcattttgg gctagtgcct gtatattgct
    13861 ttgaatcttc atcaagaggt attgcatcgg gtaaaggctc tcgctttgca catagagcag
    13921 cgcattgaac caatcattcc aataggttaa ggctgagaac aggctaatgg ttgcaatccc
    13981 aggaactgcc aaaggtaaaa cgattttcat aaaaatcatc aattcacctg cgccgtccat
    14041 acgagcggat tcaataatac tatcaggaac ggtcttttta aagaaggtcc tcatcaccaa
    14101 aatgccaaag ggtcccagag ccatcggtaa aatcaaggcc caaaccgtat cctttaattg
    14161 cagcaggtta ctcaccacca aataattggc taccataccc ggtgcaaaaa gcatggtgat
    14221 caaggcatag atggtaaaaa aacgcctgta gggaaaataa ggtcttgaga tggcataagc
    14281 ataggttgag gtcattgtgg tattgataaa ggttcctaaa acggtgataa atacagacac
    14341 cgcaaacgat cttatgatcc gatgagacat agccccttgg aaaatataat gataagcctt
    14401 tgtcgaccaa gcagctggga aaaagctata gccatgattg atcagatagc tttcatctgt
    14461 gaaggaaata atcatcacaa agataaaagg aatgatacaa gagatggcaa aaagagcgat
    14521 taacacatta aagacagcat tggtttttgg gtcaaaggtt ctgacgttga cccttttaac
    14581 agttttcttt ttctccatgt cctcctccta aaataaggct gcatcgggat ccatacgacg
    14641 aacaaaagca ttggtgatga gcaggataca ggttccgacc acagattgat aaagactggc
    14701 cgcagaagcc atactaatat caccagtagc tgtcagggca ttgtagacat aggtatctaa
    14761 aacactggta acatcgtaaa gaggacctga atttttagga atcacataaa acaagccaaa
    14821 gtcagatttg aagatactcc caatattaat aatcaatagg atagacatca tcggcaaaag
    14881 ctgtggaatg gtgatatgtc taatttgctg ccacttactg gcaccatcaa ccatagccgc
    14941 ctcatagtag gtgtctgata ttcccttaac cgatgcgtaa taaatgatac tgttgtagcc
    15001 aagtcctttc caaacactca tgaaaagtaa aatcaagggc caccaggtgg gattggaata
    15061 ccatttgatt gggctattgc cgctatcaat gagcagctga ttaataaagc ccttatccgt
    15121 atttaaaaag gcagaaacaa aatactcaat cacaacccat gataagaaat aaggcagtaa
    15181 ggacatggta tgatagacct taacagcctt cttgtttcga agctcactca tgataatagc
    15241 gaaagcgatg gcaaaaaaga cgttaaatag taaaaaaata agattataag caatggtatt
    15301 tcgcgtaatc aaccaagcat ccttagaggc aaaaaggtat ttaaagttat ctaagccaac
    15361 ccagggactt tctttcaggc tttccataaa acctcctgct gagtaatgaa aatccttaaa
    15421 agccactaca ttagctaata ctggaatgta aaagaaaaag atgaaccaga caaatcccgg
    15481 taataccatc agcaacaaag cgcggtattt gatcacattt ttccaaaagg atttcttgct
    15541 gctgatcttt gtcgtcatct tcccaacctc cctttgcttt tcaattgatg cttcaagtat
    15601 atcaagcgct tacacataga acaagcaaca aattataggt ttgataacac aaattatagg
    15661 tatcatagca caaaatatag gaatgccgag aaagtctttt caagcacttc aaaatctgtc
    15721 atactaaggg tagctaattg gtaatatacc tgttatagga ggaattacaa tgaccttatt
    15781 atgtatcgac ataggcggca ccagcatcaa atttgctatt tgtcacaagg gcaggctaaa
    15841 aaagcaaagc agtcgcccaa ctccccaaag cctagaggac ttttaccata tgcttgacga
    15901 gcgactggct tactaccgca cagaaaagct ctcaggaatt gccattagct cccctggagc
    15961 tgtcaataaa gcaacaggta tcatcgaggg agcaagtgca ctgccttata ttcatggctt
    16021 tcccattcag caatgccttg aggagcgact aggtctgccg gtttcgattg aaaatgatgc
    16081 caactgtgct gctcttgccg aatctgctct aggtgcagga caaggcacta gcagccttgc
    16141 catgctggta cttggcaccg gtgttggagg tagcctagtg attaatggca ggattcatta
    16201 cggtgcccat ttatttggag gtgagtttgg ctttatggtc atgaatgagc gttatcaaac
    16261 cttcagcgaa ttaggcactg tggtcaatat ggccaagcgc tatagtcaga tcataaatga
    16321 tggtaaaagt tacaccggta aagaggtctt agagctagct gatcaaggag atcctgtggc
    16381 cctaaaggaa agacaggtct ttcttcaaag tctggcaatg ggggtgttta atatccagca
    16441 tgcctttgat cctgaaatga tcctaattgg tggcggtgtc tctcaggctg actttcttct
    16501 tcctgccctt gaggctgaac tggataagct ctatcagata gtcagcattt ctgatttgag
    16561 accgcagctt gctatctgcc actttaaaaa cgaggccaac ctactaggtg cctctattga
    16621 ttttatgcaa gagcatagaa aggacgagat gtggatcgat tagacttcat tgacacccgc
    16681 tttggaacaa ccaatcacta ccatttttca cagggaaatt gcctgccatt gacaggggtt
    16741 ccctttggca tgcattatct aagcgtcgaa accagtcaag atcgaggggc ttggtggttt
    16801 caccccgatg atcacagctt ttcaggtatt cgcttgacac atcaacccag cccttgggtc
    16861 ggtgattttg cgacggttac ttttcttcca gtcagcggac cgctgaccaa gggagatgtg
    16921 tttcataatc agacctccta tcgtcccaag gaggcagctt ttcggcctca tcttcttgag
    16981 atttttagcc agagacatcg gattttgacg cgagcaacag cagctgccta cagctttcat
    17041 tgtgattttt cctttgataa tggcaaagca ggcttgatta tccataaccc cggaaaaagc
    17101 tcctggcagg tgacagctga tggtaaaaca atccttggct gtgtgcaaaa catcacagac
    17161 tgtcaggata aagacctagc catgtttgtt tatcttcagt ttagcagccc tgtgctaaaa
    17221 aagcttatcg gagaagactt aaactccaaa tctcttgatg attgcagcaa gacgtccttt
    17281 acctatctcc aatttgctga tgacctcaaa catcttgagc ttagggcggc tgcttctttt
    17341 attagctttg atcaagctca gctcaattgg cagagggatt tccccagatc atttgaaaaa
    17401 agccttgaat acagccgcaa ggagtggctc agctacctca gtcgtattga cattaaggat
    17461 aaagactttg ataaggtcaa ggcctactac cagcattttt accgagccct gctatttccc
    17521 caaagatggt atgaaatcac tgcaaccggg caggcgattc actataatac aacaagtcaa
    17581 agacctgttg ctggaaaata ctataccaac aatggctttt gggatactta taaatctgtc
    17641 tatcctttgc tgtctctaat tgcacctgag atttatgctg atattttaga gggactcttg
    17701 tcagcttatc aggacaccaa ctatctgcca aaatggctgt ctccagatga gcgaggcctg
    17761 atgcctggaa ccttggttga tgctgttatt gctgatggag ctgtcaaagg catcagaaaa
    17821 gacctgatgc ctgagctttt agaggctatg ctggcaactg ccaatacaga cagtcaagga
    17881 acaggctatg gccgcaaggg caatcaagac tatcaagagc taggctatct gccaaatagc
    17941 taccaggaaa gcgtcaatca gactcaagat tatgcttata gtgatttttg tatcggccag
    18001 gtagctgccc ttctgggcaa gacagcactt agtgaccaat accacacgcg atcactcaat
    18061 taccgccatt tggtcgatac tgataccggc tacctcaaaa gcaaggatcg acaagggcaa
    18121 tggcaatgtg gctttaaccc tatccactgg gggcaggact acaccgaggg ctcctattat
    18181 caaaatggat ttgcctttta tcatgatatt ctaggttaca ttcgactgat cggaggaaac
    18241 gccgccattg ccaaaagact tgaggagctg tgcaatcatg agcctgtgtt tgacgttcac
    18301 agctatggct ttgaaatcca cgaaatgagt gagctagccg cacaggattt tggtcagatt
    18361 gctatctcaa atcagccaag ctttcacctc ccctatctct atcactatat cggtcagcca
    18421 caatacagtc agctaatcct taaaaatctg ctcagtcatg cctttaccga tacaggctac
    18481 ccaggagatg aggacaatgg cagtatgagc gcgtggtacc tgttaaacag ccttggcctt
    18541 taccctgtta caccaggaac tgggcaatac ctgattggta ttccaactgt agatcaggca
    18601 accctttatc tgccaaatgg caatactatc caaatcagct gtaggggcaa tgtccctcaa
    18661 taccaatttg tcaaagaggt caagctcaat caggctagct acaacaagct ctacatcaat
    18721 catgatgatc tgattcaggg ctgtcagctc gactttcagc tgggactagt tcccccactc
    18781 aagcactatt cggctgagga cctgccctac tccctaaccc gttaaaagct aaaaaaagca
    18841 tgtcatcact cgtactacag caagccatga catgctttta gttatgtgac tttagtccgt
    18901 ttcgctccgt aggtacgaaa caataaatca cccgttagac ggatagttat gatgttagga
    18961 aatcctcttt tacattcctt aatcgctatc actggcatag ctcatcagca agcccttatg
    19021 ctaacccatc accctagcag gtaaaaccgc taaagctact agctgctcct gtaaaatctc
    19081 tcttagcttc tctaaaccta gctttaaagg agattgggct ggcttttgtg tttttcttct
    19141 tttcttagct aattccattt gcctctgcca cctccttaaa ccaataccct gattttttca
    19201 cacgccgacg ctgagtgcgg tgattatttt ctaccagacc ataacggttt ttataggcat
    19261 ttagccaaga ccagcaatta ataggtgtcc aaacatgata gccaaagcaa ttagagcccg
    19321 cttgaatccc cttatgaaga taggtcaggt gctcttttaa aaactgaatg cgatagtcgt
    19381 cttgaatctg tccgctctca tctcggtaac gatcctctcc tgaaatccca accccatttt
    19441 cagataaaaa ccaagggata ttcctatact gatcacgcat ttttagagca atatcataga
    19501 ccgcctctgg ataaatctcc cagcccttgt ccacattcat acgacgctgc ggcatcagat
    19561 aggcatcata ataccactca ggactccagg aagggctaat cacaggaata acctctggcg
    19621 ccttcacgcg cttagggcgg taaaaattaa tgcccacgta atcaaccgta taagcagcca
    19681 taagatccag ctcctctggt gtggactgcc agagcactcc atctctttgt agtattgcta
    19741 ccagctcctt tggaaagcta ccgtaaacag cagcagacat aaagaggtca ttgtgccaca
    19801 gctctgcaac atgagcagca gcaagatcag cctctgaatc agttgccgga tagatcggtg
    19861 tcagattgag aatggtacca acactgccat tgctcagctc tgctgcttgt tcttggtagg
    19921 tacagataac cttagccgtt gcaagtgcta gattataagc cacctgtacc gcttttttcc
    19981 catcaacaat ggcagggtag tggaattgca gcaggtatga gccctccacc acaaccatgg
    20041 gctcattgtg tacaaaccaa tccttaacgc gatcgccaaa ctgctcaaag catactctag
    20101 caaaggcaac aaacaaatcc acaacatgct ttgattccca accgccatat ttctgataaa
    20161 gagcaattgg caaatcaaaa tggtgcaaat tgatcaccgg acgcatacca tgtgctaggc
    20221 aggcatcaat caccctgtta tagtaagcca gtccatcggg attgatcgtg gctgtctcaa
    20281 aatcatcaat taagcgtgtc cactggatag aggtccgata ggaattgtga cccaaagacg
    20341 ctaataaagc taggtcttga tcatactgat gaaaaaaatc agaagccgta tcaggtccaa
    20401 cataatcata aaacagctca ggattttgct cataccaata atcaaataaa ttgcgatgcg
    20461 gcttttgaaa gcagccttca ctttgagggc ctgatgtagc acttccccac caaaatcctt
    20521 ctggaaactc tagcatgtcc cttgttctcc cttataaact aattaagtat aatcctcagc
    20581 tctagcttca gcgacctgtg cctgattgcc tagcatgcta ttctcctgaa gatagtgcaa
    20641 ctgataaaag cggcttggaa tattgcttcc aattcgatgc ctttgctcct gaagctcagc
    20701 atattgctgc tcaagatcag gcgcttgctc taaaataacc ctccaaaagc tctgatcagc
    20761 cttagcccga tcaaaccaag gagcaatagc ctgttgaaac gcaggaatat caagctcttt
    20821 cagcttatcc accagctcta ccagctcagc tacccaacca gataagctag ctatgtcctt
    20881 acgcataagg gcctcctcca cctcaaaggg gagatccctg tgcaaatgac gattgccatt
    20941 atgccaagca aagcgcaaaa gcgctaaagc catagcctta tctccagtat agtctctcaa
    21001 ggcctctagc caagaatagc ttggctgata acgcttggcg tcccacaggt agcgactcat
    21061 atcaattaaa gtcggctttg atagttccca gctaatcatt ggattagaca caatccccct
    21121 gacctgatag tctggctgac acaagaaagg agagcgattg gcaaacgggg tcaaaaagag
    21181 cctcttagaa tcgtcctgat aatcattgac agggatatta tcccagatga ttatgggccg
    21241 ccggtagatg gctgctattg tctcaatatc tgcctgagaa atctgactgg ccagagtgct
    21301 tgggccagtc cagaaaaaag ccacctcagc aggaatagcc tctgataact ctgctaaata
    21361 aagagagtca tgatgattat catactctgt cggacagaca accaagtcag gggctgcatg
    21421 ctgccgctgt aaaaactggt aaacagctgt tgccaaatgt gcttgggcat aggctgtttt
    21481 tttgaaacgt ctctcaactg ctgccactat ttggtaatca atatcatcaa gcagcaggcc
    21541 aaaatgacaa acacccaaat ccaacaattg ctgcaatttt tgatagagca gctgatagtc
    21601 ctcttccttg gtgtagtcaa aatcaagccc cggactaatc atgtaccaaa agtcaacctg
    21661 tctttccttg gcaagctgga tcagatccct aaaatgagcc acccaatcct ctggataggg
    21721 ctcacgccag tggctgcgct gatagtcatc atttttaggg gcatacatgt aggtattcat
    21781 gcccttatca gcaataaagc tcaagcaatc taaacgctcc tcacgcgtcc aaggggtgcc
    21841 ataaaagcct tcaatcacac cacgcatggc aaaggacgga ctatgcctaa ccgaaacaat
    21901 cggcaaataa agcctgccct ctttaacagt cattaccttt tctaaagcct cctgagcata
    21961 gcgaaagcct cttaaatttt ggctttcaat cacaagctcc ttatcctctg aaatggtcaa
    22021 ggtaaaggca tccctagcta aggtgcggtt aaaaacgtgc ttaagggtca agtcagctgc
    22081 tccctcctca acccagttga catagactga cgctgtaaga ctaggcttca tagctgtttg
    22141 gttctcaaat cggaaaaaac gaccaacaaa gcgacaggaa acaggggcgt caaaaacgag
    22201 gtaatcacct ctggttatca cctcctgata gtccttgagg gcttgataaa tagacatgac
    22261 acttctcctt tttatagcat ttctagggac ttttgactgc tttctctgat aaagacctta
    22321 acaggaagct gacaagacgc cgtctgctga tcaggccgag tcagccgctc tatcaatagt
    22381 tgcgctgctt gctgccccat ctggtaaaaa tcctgtgcag ctgttgtcaa ttgagggctg
    22441 attaactgag aggcttggct gttgtcaaag ccaacaacag ctacctgatc aggaatagat
    22501 agcccgacct gtagaatttt ttggatcaat tgaatggcta gccaatcatt ttcaaccact
    22561 aaaccagtct tttcagctgt agcagccgtc agctcatcaa ccaatcgctc aagataagca
    22621 gcattgcttt ctgacttcag cttcacaaaa taattggcct caagctctgt ttccgccatc
    22681 gcagccaaat aacccaaata acgatctcta acagaggaaa cctcaccaaa ggaagcagtt
    22741 gccacaaaca tgatccgacg gcaatcctga tcaatcaaat gcttggtcaa ctcataggct
    22801 ccgcccttat tgtctgcaac aactgctgga aagtcaaaca ggtctaaggc cttatccaaa
    22861 agcaccagag caagcccacg ctgggcacaa taaaagagca gctcaatact atgattaacg
    22921 tcttctggat aataaatcac accagcataa tcagctagct cctccaagct taccgtactt
    22981 gtaagctgga ccatcaggcg atagcctttg tcagcaacga ccgtcatgat tcctttagca
    23041 taatctccca attcgtaatc agaagcaaag ggcaggatca acaaaatgtc cttattaggc
    23101 tgagtagacg gtggtgggcc atcggtcaca aagctgccct tacctctgct gcgtgtaatc
    23161 aagccctctt gctccagctc tactaaggct cgcttagagg taatgcggct caccgaaaat
    23221 tgctctgata gggccttttc tgttggtagg cggtcacctg cctgtaattg ccctgaatca
    23281 atttgttcct tgataaaatg atatatcttt ttatatagta attcagtcat tttttactcc
    23341 ctctagcagt atatcacgaa aaaaaagact tgtaaacctt ttctaaagtg gtagacaaaa
    23401 ataaagttat atcttataat taaaaaagat atcaaatgat atatctttta ggaggatatg
    23461 atatgacaag acctattcct agcagtgtgc tcaggtttat ggacacgatt gaagagctct
    23521 gcggtgaaga gcaccgtagc tgggccatta attttaaagc cagctttgcc aacaccttgg
    23581 aaacgaccct aaaaatcgac gaagatggga ccagctttct tctaacgggt gatattcctg
    23641 ccatgtggct gcgtgattca actgcgcaac taaagcctta tctcttttta gccaagacag
    23701 atgctggcat gagacaaatc atagcaggtc tcgttaaacg tcagttccgt tacatttgca
    23761 ttgaccccta tgccaacgcc tttaacgagg aggaaaatag caagggccac caagcagacc
    23821 acacccagat gggaccttgg atttgggaac gaaaatatga gattgattcc ctctgctatc
    23881 cgatccagtt agcctatctg ctctaccgag agacagactg tacagagcat ttcaatgagg
    23941 atttccacag aggaatcaag ctgatccttg atgtctggag cacagagcaa gaccacactg
    24001 cctctcctta cagctttgag cgcgacacct ggcgtaagga ggataccttg acccacaacg
    24061 gtaagggagc tcctgttgcc tatacaggca tgacttggtc tggctttaga ccaagcgatg
    24121 atgcctgcca atacggctac ctcgtgccgt ccaacatgtt tgctgctgtc gtcttatcct
    24181 atcttgaagg gctctatact gatctcttta aggatcaaac gattgctagg agagctcatg
    24241 cacttaggct tgccattcaa aaagggattg aggagcatgc tcttgtaacc aacagccaag
    24301 gagagatcat ctatgcctat gaggtagatg gcctggggca ctatactatc atggacgacg
    24361 ctaacattcc aagcctcctt gcggcaccct atcttggctt ttgtgccaag gacgacccta
    24421 tttacctagc cactcgtcaa accattttaa gcccggaaaa tccttattat taccaaggca
    24481 gtgctgcttc tggtattggc tcctcccaca cgccaccaaa ctatatttgg catattgcac
    24541 ttgcccttca gggcttaact gcacttgatc aaaaagataa agcagatata cttgatttac
    24601 tggtggctac tgacgcaggc acccacctga tgcatgaggg ctttgacgtc aatgatccga
    24661 gtcactatac acgtgaatgg ttctcatggg caaacatgat gttttgtgag cttcttcttg
    24721 attatctggg ctttaccatt agcccttaga aagtgagtca gtgatgacac ctaaaaaagt
    24781 acatatcatt tcacacagcc attgggatcg cgaatggtac atggcttatg agcagcacca
    24841 catgcgcttg atccagttaa ttgacgattt actagacctt tttaaaacag accctgattt
    24901 tcatagcttc catctagatg ggcaaaccat tatcctagat gactatttgc aggtcaagcc
    24961 tgggcgtgag gccgagatta gacaggccat tcaggctggt aagctacgta ttggcccctt
    25021 ttatatccta caggacgcct ttttgaccag cagtgagtcc aatgtccgaa acatgctggt
    25081 tggcaaagag gactgtgagc aatggggggc aagcgttcca ctgggttatt ttccagacac
    25141 cttcggaaat atgggacaaa caccacagct aatgcgaaaa gcagggctaa atgccgctgc
    25201 ctttggacgt ggtatcaggc ctacaggctt taacaatcaa gtggatacaa gcgaaaaata
    25261 cagctcccaa ttttctgaaa tgatctggca gggacctgat gatagccgca ttctcggctt
    25321 attatttgcc aattggtaca gcaatggcaa cgaaatccca accgaggaga aaaaggctcg
    25381 acaattctgg gatcaaaagc tagcagacgc tgagcgcttt gcttctacca ggcacctgct
    25441 gatgatgaat ggggttgatc accagcctgt tcaactagac gttaccaagg caattgccct
    25501 tgcaaataag ctctaccctg attacgactt tgtccactct tgctttgagg actatttggc
    25561 tgatttaagt caggagctgc ctgaggagct ctcaattgtg tctggtgaga tgaccagcca
    25621 agaaacggac ggctggtata ccttagccaa cactgcctct gctagaattt acctcaagca
    25681 ggctaatacc agagtgtctc gtcagcttga aaatatcaca gagcctcttg ccacgatggc
    25741 ctttgaggtc acaggtacct atcctcacga ccagctgcgc tatgcttgga aaacattgat
    25801 gcaaaaccac cctcatgact ccatttgtgg ctgtagtgtt gatagtgtcc accaggagat
    25861 gatgcctcgc tttgataaag cctatgaggt ggggacttac ttagcagagc gttctgccaa
    25921 ccaaatagct gaggctattg atacctccat gtttccagag gatagctgtc cttttgtcct
    25981 cttcaatacc tgcggtcatg agaaaaaaac ggtctccgac ctcaccctga catggaagat
    26041 ttttccattt gggcaacgac tgcctaaagc tgtttatcaa gaagcaaagg aatacctaga
    26101 gacaagacag ccacaatttc aggttattga cgcagctggc aggatcatag aggaggctga
    26161 aatcttaggc acagacatcg cctttgatta tgccctgcca gagcgcacct tcagagaagc
    26221 ctactttgcc atcaaggtac agctaaggct cccactgact ctttctgcta tgtcatggca
    26281 atgtcttgca ctaaaagaga ctgatcagcc ttgccaagca actgacactg acaaaatgct
    26341 ctttcatcag gacaggagct gtcttgaaaa tgatttccta aaagtcatca tcgcagcaaa
    26401 tggccttcta acgattgaag acaagctaaa tggcaatagg tttgacagct gtctccaata
    26461 cgaggattgt ggtgatattg gtaacgaata tatctttcgc cagccagatc atgatagccc
    26521 ctaccttgct catcaaggga gctgtaagtt gcgggtcttg accaacacag cctatcttgc
    26581 tgaaatcgaa ttgacacaga cctttgatat tcccttagct acagatgatc gtctaaaggc
    26641 tgaaatggag gctgtcattg acattagaga gcgtcaggcc aaacgctcac aggaaaaagc
    26701 gccctttaca gtaacaacag ttattcgtat ggaaaaagac agcccacgcc tacaatttca
    26761 gaccagcttt aacaatcaaa tgacaaacca ccgcttgcgc gtgctattcc caacccattt
    26821 aaagacagac caccattttg cagatagtat ttttgaaacc gtaaagcggc ctaatcatac
    26881 caatgcccaa ttctggaaaa acccaaccaa tcctcagcat caggaggcct ttgtcagcct
    26941 ttttgatggt aggactggtg tcactgtagg caattacggc ctcaatgaat acgaaatcct
    27001 accagatacc aataccatcg ctatcacgct cctacgaagc gtcggtgagc ttggagattg
    27061 gggctacttc ccaacccctg atgctcaatg cctcggtcaa cagactgtca gctttagctt
    27121 tgaaagcatt aacgctacca cacgctttgc cagctattgg cgagctcagg aggctcaggt
    27181 accagtcacc atggcgcaaa ccaagaggca ttctggccag ctgccagctc aatatgctta
    27241 catcaaagga gcaactgatc acgttgctct cacagccttc aagcgtcgcc tatccgataa
    27301 tgccctaatc acgcgcagct ataatgtatc aaatgacaag gcctgcgctc ttaccctagc
    27361 aatcccagac cacacagcaa gggttaccag cctactagaa gaggatcagc atgaacccct
    27421 accagctgag cttggcaagg gcgaaatcct aaccctagct tggaaaaaga gtgaatcagc
    27481 tcatctataa ccagattacc actaccttga cctaaatcac aaaaaagtcc ttagcattaa
    27541 cgctaaggac tttcagcatt gtctattcga aaaatctata gaagaatagc aatctcttcc
    27601 tgacacaaag gaataacagc attgtcaagc taattgctgt agctcgacag tccagactaa
    27661 atgtctcaga gcttgcctct attgtagatg acagatgtcg atgatgtcat caacgcggct
    27721 aaacacattt gggtcatgag tggcaaaaat cagaacagta tcagggctca ccaaactaag
    27781 caacagctca ataatctcat cacctgtttc cttgtccaag gcacccgttg gctcatctgc
    27841 caaaataatg caagcctttt ttaacaatag gcgtgcaata gcaacacgct gagcctgacc
    27901 acctgataat tcataaatgt tctgtgagag aaaactactg tctaagccaa cgctatgcaa
    27961 ggcttccaca atgttagatt taggagccag cattttaaga ttgtcataga ctgtttcttc
    28021 ctctatcagt gcataatttt gaaaaacata gcccaaataa tccttaaaat aatcttgctc
    28081 tttcatgctc caaatgtctt gaccatttac taaaatctga ccactatctg gcttttcaag
    28141 gcgagcaata gcatttaata gggtggtctt gcctgatcct gaaggaccta caagtgcata
    28201 agaacgattg gcctcaaaag tcaagctaag cttgtcataa attgtctttt ttccataatg
    28261 tttggaaagc tgttttatct caatcataat atgtcaaaat ctcctttgat gatttgaatc
    28321 cgatgcttca aaatagcctg ataagcaaaa aaggacatac aaacgatttc tcctaaataa
    28381 agcaggccaa tgcctagtac catgagccta tttccagtaa ggattcccat cattcctatg
    28441 gcaagaaaca aacacaaagc taagggcaat aacaatctac caatcaaaac aaggcttttt
    28501 tgccccatca agaaccagac ggaaatcttt ttggcctttt gtttcatcag agaaacaatg
    28561 tattcataaa tgataaagca ctgggcaatg gcaaggaccg ttaaggcaat aacacttccg
    28621 atgagctggc ttaggatttt atggcgctct aaaatcaaat gattggaaac attggtcaaa
    28681 ctagagaaat tcgtcaagcc tgcttgtgtt aatcgatcac gaataagcgc ctgacgatag
    28741 atagattttt gagccatttc tccaaacttc gtcaataatg atggctccgt catgaacgaa
    28801 aagtttaact gcactaatat agtattcact tcttcttgct gagcaaaaat gtcttgttgg
    28861 tcttgcttat gattaaacag aaagctcttt tgtccgtcag gaacctcttg aacaaccaat
    28921 tgattagcct ttaggctgct atattgaaac cattcataat tgacaatgtt taaaatgctg
    28981 tcagcatctc ccatcatatg tttagaaata taaatgactc ctacagcatc agctgctggc
    29041 cttccgtaat cattgttagg gaaaatgtct ttatttttta gcataaatcc ctgattgaca
    29101 taacggactt ttgacgcaat ccttggatca accccattgg tctttaactc ttttttgaag
    29161 tcatcaggag ctgattgtaa attggtttcg ttaaggcttg aaagtgctga ataaataacg
    29221 tcattatcag aaaaagacag gagaaaatgt tgatagcgct gattttcttc cttgaaataa
    29281 tcactatcaa tttggtgatt gtcatcagta tgcgtactca aggtatctag ccatgttatt
    29341 tccgcaaaat ccttagcttt atcccatttt cctagaactt gaatgtcatt ggcagatttt
    29401 cctatagtct ccaagctttt gtgtagggaa agcccaaaaa tgacgctaga caaacaaatc
    29461 cccaccaacc agacaaagag gaccaaaggg gttgcttgtt tattttttag aatggctagc
    29521 gccttcaacg aacggatatt gatgaaaaat aaagcatgaa cagcaagcat cagcaataat
    29581 aaaatgacag cattagtcaa gatcagaagt gtaaatgact tgacaaaaac attggagata
    29641 ctgccttgat agagaatgaa gaggagaata ctaaccgcaa agctagctcc catcagcaac
    29701 aaatcctgta gcaactcctt gcggctatag tgttcaaata agcccaggct tcttagtatc
    29761 atagactttt tagcatacat caatttaaca gcaaacaaga ggagggcaaa cacaaaaaag
    29821 agggtccaaa tagctaagga tcgtaagttt gtgaacaaaa aataataagg caagagatac
    29881 caaggtaaat cagcaccttt gtaggtcaag ccccgttcag tcatcgcggt ttcaaatgat
    29941 gaaggaagag acctcgtcgt gtagtacatg ccactaagat cgtttgtcaa gagctccttg
    30001 cgattactgc tatagacagt ctttttccca tttgtcccaa acaggtaggt ggcttcttta
    30061 ccagtatgat ctaagtaggg acgataaatt tggatatgtt cctgctcggc taaggcttcg
    30121 atcctgtcta aaacgtgtcc cttatcaaca tctttgtttg aagccactaa tgaaaatgca
    30181 gcctgaacag ggtatttgat atcattgcca tactccttga ccgcaccaaa tgataaacat
    30241 gtcaaaagca gaacgaaaat acagataact gtagctctcc acctcataaa aacctccttg
    30301 agaaaagttg actaagagga taatatcttc atccactaaa acgtacaata aaacattaaa
    30361 cctgatacca gccataacat gactttgctt gaacccaatt ccactgcttt tttacaccgg
    30421 cacgagccca accattgttt tgactatctt tactatttac atttccccaa aagtctgtca
    30481 cagaagcact acttcctagc ccaataggaa ctccaagaaa agcgtttgag taagatcagc
    30541 tagcactggt aattccaaat tcccaagtgt ccttatactt tggatgaggg tgcctagtct
    30601 ctgcgttaac attagatatc ccagcaacta cgaaagctcc aaccaagcca aggctcataa
    30661 accattttac acttcttttc atgtcgtgta ctctcctttg ttaaaataaa gtaaaaaaat
    30721 cttaactagt atcaggatcc ttttacaaca caagtgtatc atatcataaa agctttttgg
    30781 gaaagagctt aagttttttt gcagctcatt ggcagaattg tcaagggcaa aaaaagatat
    30841 taaaaagacc aagcttaaaa aataatttct tttttctcat ttttaaagct atgacactag
    30901 gactgctgta gctgacctag tgacaagctc agacataacc atctcctgct accaccattt
    30961 tataacaggg cctgaagagt ttttttatga ttgcggttat cagtcaaaac ttctcgtcaa
    31021 acaatacaaa aaaattagct tcctctgaca ggacctaatc cttttgtatt aatctaagct
    31081 tttataaggt gtcattcaga ctggtgcttc tggcaaagaa aatccctaaa tgacatcact
    31141 gggcgagggc gtacgtcatg ctctcccagc agtttctcca tccaaatcat atcaaaccac
    31201 tggttaaact tatagcccga ctgatgaaat ctgccaacca accgataacc gagtttttca
    31261 tggaagactt gactgctatt ggtcagataa ggcgtagcat gcgctgtact agcgatacag
    31321 gcattacaat ttaagattcc catacctttc agataaccct ccaaacggtg atacaaggct
    31381 gatcccaagc ctctccctct agcctcctgg gccagataaa tggtcacctc agcagaccaa
    31441 gcataggctg cgcgtgcatg aaagcgacta gcataggcat aacctaaaat gcctccctcc
    31501 tcttccacta ctagacaggg ataaaagacc ataatgtcag acagacgtcg ctcaaactcg
    31561 gtcaagctag gtacagtgta ctcgaaggta acagcggttt cctcaacata aggacggtaa
    31621 atatcaagta aagccttagc atctgctaag gttgctaaac gaatcctacg cattaatagc
    31681 cctcctagtt ttcccagtat actccaaaac aagggccttg tcaaaaacac tgatagtaaa
    31741 aaagcctgat ccctaaatga aataggttgt catatcgctt gcagatagac agctctaccc
    31801 cctcaaaagc tattttaagc gtttgagcac acaaacacta ggtatcgtcg ctttaaggct
    31861 gatacctagt gctatagctt atgattaact ggttaaggag gtgatttcaa gtaccagtac
    31921 cacctcaagc tattaacgac gataagcttt tgcgtatctg atcccccaaa tcatcaatcc
    31981 catagtgaca aatgatataa aagagcatat cacagcaata acctgcttat aaaactcaga
    32041 cgagcttaga ccacaataga ttgacacaat gcctataatc ataaacacca ctataaacag
    32101 gatctgagtt aataacagat tgggacgtgt ttgttccttc aactgctcaa tcgcaatttc
    32161 tcgtgaaaaa tagtaattag aagcagcagt gcttaccgca aagatagcaa aactaatcag
    32221 tgatcccaaa gaaagcctat gaatgtcttt tgaaagaaga acagccatca agctaatagc
    32281 tggtagctga ccagttaata gcctaaaaat catcaaataa tgtagtcgct tcattttatt
    32341 aagcattaca acaccttgcc ctttcttagc aagtcagtgc gccacctatt cctccaatag
    32401 ctgcgtcaca aactctatta attttttcag cctcaacata agcaagtcta ccagtaccta
    32461 agcattaaat atttcatcaa tgctgtcgtc cacatgaata tttcctatgt ttagcaactg
    32521 gcaccagtat agcatattac cagctgcttt cagtatttaa gtcttaaaat gtcgtcgaaa
    32581 cgtcttaaat ggtaatacga aaactgttga caccgattaa gcgcatttct aatacccgta
    32641 accaatatga gaaagctgtc ttaatgcttc aaagactgag tttcctctga ggtctctctt
    32701 tagccatcat gctcccctga taacatttga aagcactcct ttcca
//
LOCUS       DARYXS010000012        32061 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.012, whole genome shotgun sequence.
ACCESSION   DARYXS010000012 DARYXS010000000
VERSION     DARYXS010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32061
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.012"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TV193_000446"
     CDS             complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TV193_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEL1512679.1"
                     /translation="MSDINETVAPQPIDLGDYQFGFHDDVEPIYSTGKGLNEAVVREL
                     SAAKDEPEWMLEFRLKSLEAFHKMPMQTWGADLSDIDFDEIIYYQKPSDKPARSWDDV
                     PDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKAEFEKLGIIFTDTDSALKEY
                     PELFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNEHTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALKDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANTGQHQDT
                     GAKMVHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKLSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLIAYEMEGSVG"
     gene            complement(1584..2021)
                     /locus_tag="TV193_000447"
     CDS             complement(1584..2021)
                     /locus_tag="TV193_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEL1512680.1"
                     /translation="MALSKLSSLYMAVVADHSRHPHHHGQLEGVEAVQLHNPTCGDVI
                     SLTIKFADDRIEDIAFAGDGCTISTASSSMMTDAVLGKTKEEALALADIFSNMVQGND
                     DSNQALLGEAELLAGVANFPQRIKCATLAWHALKQAIEKSDEF"
     gene            complement(2008..3234)
                     /locus_tag="TV193_000448"
     CDS             complement(2008..3234)
                     /locus_tag="TV193_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1512681.1"
                     /translation="MFDPNQIKADFKLLDQYVNDEALVYLDNAATTQKPQAVLEAMQA
                     YYQKDNANVHRGVHTLAERATRQYEASRQKVADFIGAKSSKEVIFTRGTTSSLNWVGK
                     FAEQVLKPGDEVLISIMEHHANILPWQQVCQKTGARLVYAYLKKGKLDMNDLQSKLGA
                     STKFVSITHVSNVLGCVNPIQEIARLAHARGAYFVVDAAQSVPHMAIDVQELDCDFLA
                     FSGHKLLGPTGIGVLYGKEALLNQMNPVEFGGEMIDFVYEQEATWKPLPWKLEAGTPH
                     IAGAIGLGAAISYLEAIGMDQVHAHEADLVAYTLPRLQAIAGLTVYGPDRSDERSGVL
                     AFNIDGLHPHDLATALDYEGVAVRAGHHCAQPLHKYLGLHSTVRASFYLYNTREDCDR
                     LIEAILKAKEFFNGTF"
     gene            complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TV193_000449"
     CDS             complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TV193_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEL1512682.1"
                     /translation="MTKEKILAFSQAHAEPTWLQELRLKAFDVMPHLELPTIERVKFH
                     RWNFGDGSLTESTALGTVPDFMALGDNPKLVQVGTQTVLEQLPMELIEKGVVFTDLAT
                     ALDEIPEQLEAHFGSALAFDEHRLAAYHTAYFNSAAVLYVPDHVEIEQPIEGIFLQDG
                     DSDVPFNKHVLIIAGKESKLTYLERFESIGDKTQAASANISVEVIAQAGSQIKFSAID
                     RLGDQVTAYISRRGRLDHAATIDWALALMNEGNVIADFDSDLIGQGSQADVKVVAASS
                     GRQVQGIDTRVTNYGKHTVGHILQHGVILERGTLTFNAIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVVAEIPVPSVRQDIVTALDDKLARR"
     gene            complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TV193_000450"
     CDS             complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TV193_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEL1512683.1"
                     /translation="MSILEINNLHVSIEDKEILKGVNLTLRTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYQVTEGEILLDGVNILELEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKEDRDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGQAFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALAIRLEKEGYAGIAEELGIDYKEEV"
     gene            complement(5505..6662)
                     /locus_tag="TV193_000451"
     CDS             complement(5505..6662)
                     /locus_tag="TV193_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEL1512684.1"
                     /translation="MISFTIDDVLVLIGALLMSLLLTPIVRFLSIRVGVVDTPNARRI
                     NKVPMPTSGGLAIFTSFVIASLVLMPLASNGAHIGGQTYFQYILPVVLGGLVVTITGF
                     IDDVYELSPKLKMLGIVIGAIIVWAFTDFKFDSFKIPFGGPLLAFDPFLTFFLTVLWI
                     ISITNAINLIDGLDGLVSGVSIISLVTMAIVAYFFLPLTNFFLTLTILILIASIAGFF
                     PYNYHPAIIYLGDTGALFIGFMIGVLSLQGLKNATAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGKKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGIAMLFSLISLLLNVSSRIGGV
                     LLILGLLFALEVFIEGIEIWGEKRTPLFNLLKFIGNSDYRQTTLSKWKQRK"
     gene            complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TV193_000452"
     CDS             complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TV193_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEL1512685.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAV
                     MDELGLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDLNKDLNFEDLADLGDISQMTPED
                     FFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
                     HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARL
                     IEHASPGTKTRAYLQEHGCQLIFDGAVEELQKIRLG"
     gene            complement(7553..8392)
                     /locus_tag="TV193_000453"
     CDS             complement(7553..8392)
                     /locus_tag="TV193_000453"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEL1512686.1"
                     /translation="MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKA
                     FMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIA
                     VPLDDWFDAHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGC
                     FQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGN
                     HLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFK
                     SLF"
     gene            8708..10276
                     /locus_tag="TV193_000454"
     CDS             8708..10276
                     /locus_tag="TV193_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1512687.1"
                     /translation="MKKLVLSCLATLLIFLGGIGTVQADHYLRVGMEAAYSPFNWTQD
                     DSSNGAVPIEGTSQYANGYDVQIAKKIAKALNKDLLVVKTSWTGLIPALTSGKIDLIA
                     AGMSPTAERKKEIAFSNSYYTSEPVIVVASNGKYAKARSIKDFSGAKVTAQQGVWHVN
                     LLPQLEGAKLQTPMGDFSQMRQALTSGVIDGYISERPEAMTAETANKAFKMITLTKGF
                     TVSESDAAIAIGMKKGDDRLTAVNQVLDAISQKERLALMDKMIQQQPSEPKADEAKPS
                     FIKQTWSIFQSNWKQFLRGTGMTLLISMIGTITGLFIGLLIGIYRTAPKAKGKLAALA
                     QRLFGGLLNVYIEVFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIVIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRQIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQVSEVPNV"
     gene            10269..11009
                     /locus_tag="TV193_000455"
     CDS             10269..11009
                     /locus_tag="TV193_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1512688.1"
                     /translation="MSNPIIEIKNLKKSYGNNEVLKDISLTVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGEILFHGDNVLAEGYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRERSEAEKIAKENLKAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVAEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRVIFMDKGL
                     IAEEGTPKQLFEQPKQDRTKAFLQRFLS"
     gene            11357..11473
                     /locus_tag="TV193_000456"
     CDS             11357..11473
                     /locus_tag="TV193_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEL1512689.1"
                     /translation="MAEKTDLASAYRRLKSPNIKTKKRALKIIHEHKRYGKK"
     gene            complement(11997..12887)
                     /locus_tag="TV193_000457"
     CDS             complement(11997..12887)
                     /locus_tag="TV193_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEL1512690.1"
                     /translation="MLEAILIIGFLVIVILSIMASTLYVVRQQSVAIIERFGKYQGTA
                     TSGIHIRLPFGIDRIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVIDA
                     YYKLIKPEAQIRSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLADSIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTLNGVDDIRTQVLSALKTR"
     gene            complement(13150..14814)
                     /locus_tag="TV193_000458"
     CDS             complement(13150..14814)
                     /locus_tag="TV193_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEL1512691.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKSKEE
                     LTGKDLAQAFQMGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDNAIEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVASEDFKATPANM
                     SEMIKAEHHKSVAGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKIDNEPTKA
                     EAKEFGLIAVVAGDGLAEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVETRTIPQGFTSLLAFDPSKTLEDNVADMTASLSDV
                     VSGSVTLAVRDTTIDGLDIHENDFLGMVDGSIVVSNPDMEATLKTTFDHMIDEDSEIV
                     TIFIGEDGSSEVAQGLADYLEETYEDIEVELHQGDQPVYPYLMSVE"
     gene            complement(14814..15179)
                     /locus_tag="TV193_000459"
     CDS             complement(14814..15179)
                     /locus_tag="TV193_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1512692.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSALKD
                     NFQSLLRKENYAKGVVVKSTDMGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LSADMVNVYVQNIKVVGEN"
     gene            complement(15331..15519)
                     /locus_tag="TV193_000460"
     CDS             complement(15331..15519)
                     /locus_tag="TV193_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEL1512693.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            complement(15979..16344)
                     /locus_tag="TV193_000461"
     CDS             complement(15979..16344)
                     /locus_tag="TV193_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512694.1"
                     /translation="MADLSISKKSLLKGLGLLSVCLGLAVGTSRTAFAHVSTFYWNRS
                     WYLSQQNKGTDEEVEQKKKELIKKIKDSDLDGFIMGNYIDTINSHVFLYKLLHLEEYI
                     DFLIAQFDHFTPEQLEKRD"
     gene            complement(16934..17815)
                     /locus_tag="TV193_000462"
     CDS             complement(16934..17815)
                     /locus_tag="TV193_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEL1512695.1"
                     /translation="MPIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKLAKVLIETLVESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLEKAREIVKLAHAKGVSVEAEVGTIGGEEDGIIGSGELAPIEDAK
                     AMVATGIDFLAAGIGNIHGPYPENWTGLDLDHLKKLTDAVPGFPIVLHGGSGIPDDQI
                     QAAIKLGVAKVNVNTECQIAFANATRAFARDYEANVAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
     gene            complement(18018..18103)
                     /locus_tag="TV193_000463"
     tRNA            complement(18018..18103)
                     /locus_tag="TV193_000463"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18067..18069),aa:Leu,seq:aag)
     gene            complement(18158..19084)
                     /locus_tag="TV193_000464"
     CDS             complement(18158..19084)
                     /locus_tag="TV193_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1512696.1"
                     /translation="MKTIRLSKYFGILLLLLTLASVGASFYFFHVAQVREEKSFINNK
                     KRTPDNPLYPAELAFDSLTREKRSITNRGRQQVAWYLPASQDTHKTAIVVHGFTNDKE
                     DMKPYAMLFHSLGYNVLIPDNEAHGESEGDLIGYGWNDRLNLLAWIDLLVSEDKGSRI
                     SLFGLSMGAATVMMASGEQLPSQVVNIVEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKLPVLFIHGDKDTFVPTEMVYQNYQATKGPKEL
                     MVVKGAKHAKSFETNPDQYKEKIAAFLQKYEK"
     gene            complement(19444..21057)
                     /locus_tag="TV193_000465"
     CDS             complement(19444..21057)
                     /locus_tag="TV193_000465"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEL1512697.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNPEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLDVPQADMTE
                     WSAMVDRVMNLKKTTRIALVGKYVELPDAYLSVVEALKHSGYANDTAIELDWINANDL
                     TAENAKKLLGQADGIIVPGGFGQRGTEGKIQAIRYAREHDVPMLGICLGMQLTCVEFA
                     RHVLGMEKANSFELDPDTAYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKAGSRAAAAY
                     NNQEVVQRRHRHRYEFNNKFRQDFEAAGFVFSGVSPDNRLVEIVELPEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAVKNKNQSL"
     gene            complement(21331..21897)
                     /locus_tag="TV193_000466"
     CDS             complement(21331..21897)
                     /locus_tag="TV193_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEL1512698.1"
                     /translation="MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQN
                     YLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDG
                     APKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDLNEEDEEDEEEEE"
     gene            complement(22164..23447)
                     /locus_tag="TV193_000467"
     CDS             complement(22164..23447)
                     /locus_tag="TV193_000467"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEL1512699.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDQAFNKIKKDLNAPGF
                     RKGHMPRPVFDQRFGEEVLYEEALNIVLPAAYEGAVAELELDVVAQPKIDVVSMEKCQ
                     EWTLTAEVVTKPEVKLGDYKDLTVEVEASKEVTDEEVDAKVERERNNLAELVVKEEAA
                     VEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEEQLVGAKAGDTVEVNVT
                     FPENYQAEDLAGKAAKFVATVHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEAAYDDALEGAAIELAVENAEIVELPEEMVHDEVHRSVNEFMASMQRQGISPDM
                     YFQLTGTSQEDLHKQHEAEADKRVKTNLVIEAIAKAEGFEASDDEIEKEINDLAAEYS
                     MPVEQVRSLLSADMLKHDIVMKKAVEVITSSAKAK"
     gene            complement(23796..25205)
                     /locus_tag="TV193_000468"
     CDS             complement(23796..25205)
                     /locus_tag="TV193_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1512700.1"
                     /translation="MVTHKTKRFLKALSVTSLTLGLVLSGLAPLAPANLASAQEVQSD
                     NQPVAMKDGAILHAWCWSFNTIKENMSAIKEAGYTSIQTSPINAVIEGAGGSKDLKNW
                     YYHYQPTDYTIGNYQLGTEEEFKAMAQEADKYGINIIVDAVLNHTTSEIKAVSPKITA
                     IDNWTHGNDKIVNFNDRYQITQKSLLGLYDFNTQNRAVQEYMLNYLKRAVADGADGFR
                     YDAAKHIELPGEHNSDFWKVILNNGAKFQYGEILQGDACNEAGYGNIMGVTASNYGKL
                     IRKVLGQGYVKDWDLVNFQVHGVSEDKLVTWVESHDTYANDDEESTKLTDEDIKLGWG
                     IIAARNEGAPLFFSRPRGGGGQNGRFPGESQIGDAGSDLFKDPTIVAINQFRNRMNGQ
                     SEYIRNPGMDQGLVMIERGQKGAVITNLTIVDKDFSSTTTLADGDYKDAVTGTVYHVS
                     NHNITGHLAKKSVAVLLPA"
     gene            25656..26495
                     /locus_tag="TV193_000469"
     CDS             25656..26495
                     /locus_tag="TV193_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEL1512701.1"
                     /translation="MTFILTYFNQLHLENIMVLVFSKLVSITLLLIFFVIFKKITTAL
                     FEKAIAKSFSYSRQTEARKKTLSKLLHNTLNYVFYFLLIYWILSLLGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDTVTIAGIEGTISSVGIRTTQVRGFD
                     GTLHFIPNRNITVVSNKSRGNMRALIDIPLYSSTDLEHVTQIIKAVNKREVPNFPQIV
                     GQPNILGPQTNPNGQFTFRVSIFTENGQQFTIYYSFYKLYQEALLREGIKLPTASAIS
                     PLA"
     gene            complement(26591..27151)
                     /locus_tag="TV193_000470"
     CDS             complement(26591..27151)
                     /locus_tag="TV193_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEL1512702.1"
                     /translation="MNLKVLREEARSILLDIVERSAIKKGQLFVLGLSSSEVLGGRIG
                     QHSSLEVGEVIVKLILEELSFRGIHLAVQGCEHINRALVLEESVAEEYRLEIVNVLPS
                     LHAGGSGQLAAFKYMKQPVEVEAIAAHAGLDIGDTSIGMHVKRVQVPLVPIQRELGGA
                     HVTALASRPKLIGGVRARYQPDPIRK"
     gene            complement(27164..27637)
                     /locus_tag="TV193_000471"
     CDS             complement(27164..27637)
                     /locus_tag="TV193_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1512703.1"
                     /translation="MKQTRELALVSILTALTVVLGRFVSIATPTGFLSLLDAGVYVTA
                     FSLGKKEGMLVGGLSAFLLDLISGYPNWMLISLVAHGAQGYLAGLPGRHRFLGVGLAS
                     VIMVGLYFLAAIPMYGMGAAISEISGNAAQNTLGIGVGYLLYLGVKKQLVKVSDD"
     gene            complement(27643..28392)
                     /locus_tag="TV193_000472"
     CDS             complement(27643..28392)
                     /locus_tag="TV193_000472"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEL1512704.1"
                     /translation="MKNKVLTIAGSDIFSGGGLQADLAVLHQLDSFAFLAITCLTSCD
                     AKGFSIHPVATDLLAKQLSSLAAIPFQAIKVGLLPRPEIAEQVALFLELKKDIPVVLD
                     PVLVFKENQDQTVVEMTQALRSLFPLTAVITPNLREAERLAGLAINSREQMVEAAKKL
                     YEMGAKRVVIKGGNRFDQRVALDLFYDAKTLCFLEKPVLAKQNSGAGCSFAAAIAAYL
                     AKGYSPLRAVEQAKDLVFEAIQQSNDYGVVL"
     gene            complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TV193_000473"
     CDS             complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TV193_000473"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEL1512705.1"
                     /translation="MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGI
                     QIHGAGRTDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHA
                     RYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAA
                     GTSVKNKVRTITAATLTQDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQ
                     IRLVLESKNRQLAGPTAAGNGLYLKEIIYEE"
     gene            29318..30682
                     /locus_tag="TV193_000474"
     CDS             29318..30682
                     /locus_tag="TV193_000474"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEL1512706.1"
                     /translation="MKVTKFGGSSLASAQQLEKVLAIIKDDPERKIIVVSAPGKRSPT
                     DTKVTDALIAYYKAYVSDRHYHKHLEWIINRYQQICNDLTLDSKIITQIKASLEQLAR
                     LPKEHNPYLYDTFLAAGEDNNAKLVAAYLKANGLTASYLHPKDAGLIVSSEPQHARLL
                     PISYDKLEALKDHDDILVIPGFFGVTNENQICTFSRGGSDITGSIIAAGVTADSYENF
                     TDVNGIFAAHPGVVKQPQTITELTYREMRELAYAGFSVLHDEALIPAYRGKIPIVIKN
                     TNNPSHPGTTIVLEHQRKSNPVVGISGDDHFVSINLSKYLMNREIGFGRKLLQILEDL
                     NIRWEHMPTGIDDLSIVLRERELTPIKEEEILRRLVQQLEVDEVSITRNLSIIMIVGE
                     NMKSHIGVTSAATKALSEHHINIAMISQGSSEVSVMFVINSTDEKKAIRALYQTFFSP
                     DRPL"
     gene            complement(31160..31645)
                     /locus_tag="TV193_000475"
     CDS             complement(31160..31645)
                     /locus_tag="TV193_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComX"
                     /protein_id="HEL1512707.1"
                     /translation="MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRL
                     LVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQKRRFHKMAYEEIGSVGHAIPAG
                     GLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
                     K"
     gene            complement(31734..31807)
                     /locus_tag="TV193_000476"
     tRNA            complement(31734..31807)
                     /locus_tag="TV193_000476"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31771..31773),aa:Arg,seq:acg)
BASE COUNT         9541 a         7718 c         5809 g         8993 t
ORIGIN      
        1 gccaagaagt cttttttatg ccttaggtat ttaaaaacta acctcttggg ttagtaccta
       61 tgtcttttaa aaagcctatc catcaggtca ccctaatgga taaggtcaat gtagctgctt
      121 cttgactagc caactgatcc ttccatttca taggcgatca agcgattcaa ttcaacagca
      181 tactccattg gtaattcctt ggtaaagggc tcaacaaacc ccatgacaat catttcagta
      241 gcttcgctct ctgacagtcc ccgactcatc aggtaataga gctgctcctc tgaaatcttt
      301 gaaacttttg cttcatgctc aagagctacc tgagagttgt gaatttcatt gaaggggata
      361 gtatctgatt ttgagatgtc gtccatcagg attgtatcac attcgatatg agagactgat
      421 ttttttgaca gcttgttaaa ggtaacctga cctcgatagt caaccttacc accacttttt
      481 gcaatagatt ttgacacaat agacgatgag gtgtgaggcg cattatgcac catcttagct
      541 cctgtatcct gatgctgacc agtattagca aaggcaatgg agagcatggt gccacgcgca
      601 cctggaccat caaggtaaac tgaagggtat ttcatggttg ttttagcacc cagattacca
      661 tcaatccact caaccgttgc gtccttgaga gcacgcgctc gcttggtcac caaattatag
      721 acattgtcag accaattttg aattgttgta tagcgcatgt aagcaccatc taaagcaaag
      781 atttcaacaa tagcagcgtg caagctgttg cttgaatagg taggtgctgt acagccctcc
      841 acataatgca cactagcgcc ctcatcaaca ataattaggg tacgctcaaa ctgaccagtg
      901 tgttcattat tgatgcggaa ataggtttgc aaaggaatgt ctaccttgac cccctttggc
      961 acataaataa aggtccctcc tgaccaaaca gcagaattca aggcggctaa tttgttgtca
     1021 gttgggggta ccagcttagc aaaatactgc ttaaatagct caggatattc ctttaaggca
     1081 gaatccgtat ccgtaaagat aatgcccagc ttttcaaact cagccttcat gttgtggtaa
     1141 accacctcag actcatattg tgctgaggcg cccgccagat aagctcgctc tgcctctgga
     1201 atgccgatgc gctcaaaggt ttccttgatt ttatctggaa catcatccca tgaacgagcc
     1261 ggcttatcag atggcttttg ataatagata atctcatcaa aatcaatatc tgaaaggtct
     1321 gcgccccagg tttgcatggg cattttatga aaggcttcaa gtgattttag gcgaaattcc
     1381 agcatccact ctggttcatc tttagcagct gataattctc tcacaactgc ttcatttagg
     1441 cccttacctg ttgagtagat aggctcaaca tcgtcatgaa agccaaattg ataatcacct
     1501 aaatcaattg gctggggggc tactgtttca tttatatcag acattttcta ttttccttta
     1561 tacgttacta aatgagagag gacttaaaac tcatcgcttt tttcaatagc ctgcttgaga
     1621 gcatgccaag ccagagttgc gcacttgata cgctgtggaa agttggcaac cccagctaat
     1681 agctcagctt cacccaagag agcctgattg ctatcgtcat ttccctgaac catatttgaa
     1741 aaaatgtcag ctagggccaa cgcttcttcc tttgtctttc caaggacagc atctgtcatc
     1801 atactagacg aagcagtcga aatcgtgcag ccatccccgg caaaggcaat atcctcaatc
     1861 ctgtcatcag caaatttgat agtaagggaa atcacatctc cacaggtagg attatgaagc
     1921 tggactgcct ctacaccctc aagctggcca tgatgatgcg ggtgtcttga atgatcagcc
     1981 acaacagcca tatataagct gcttaactta gaaagtgcca ttaaaaaact cctttgcttt
     2041 taaaatagct tctatcaagc gatcgcaatc ctccctcgta ttatagagat aaaagctagc
     2101 acgaactgtt gaatgcagtc ccaagtactt atgcaaaggc tgagcacaat gatgtcctgc
     2161 tctaactgca acgccctcat aatctaaagc cgttgcaaga tcatgcgggt gtaagccatc
     2221 tatattaaag gcaaggacgc ctgagcgttc atctgatcgg tcaggaccat ataccgtcaa
     2281 gccagcaata gcctgcagcc ttggcaaggt ataagcaact aaatcagcct catgagcatg
     2341 aacctgatcc attcctatag cctccaaata tgaaatagca gctccaagac caatagcacc
     2401 agcaatatgg ggggttcctg cctcaagctt ccaaggcaag ggcttccaag tcgcctcctg
     2461 ctcataaaca aaatcaatca tttcgccacc aaattcaact gggttcattt ggttaaggag
     2521 agcctccttg ccatacaata caccaatgcc agtcggtccc agcaacttat ggcctgaaaa
     2581 ggcaaggaaa tcacaatcta actcctgcac atcaatagcc atgtgcggta ctgactgcgc
     2641 agcgtcaacc acaaaatagg caccccgagc atgagcaagc cttgcaatct cctgaatcgg
     2701 attaacacag cctaacacgt tagagacatg ggtgatactg acaaatttgg tgctagcacc
     2761 caattttgat tgcagatcat tcatgtctag cttgcctttc ttaagataag catagacaag
     2821 ccttgcccct gttttttgac aaacctgctg ccaaggaagg atatttgcat ggtgctccat
     2881 aatcgaaatc agcacctcat cacctggctt taagacctgc tcagcaaatt ttccaaccca
     2941 atttaagctg cttgtcgtcc ctcttgtgaa aatcacttcc ttgcttgact tagccccaat
     3001 aaagtcagca accttttgac gactagcctc atactgtctt gttgctcttt ctgccagggt
     3061 atggacacct ctatgaacat tggcattatc cttttgataa taggcctgca tggcctctaa
     3121 cactgcctgt ggcttttgtg ttgtcgccgc attatctaag taaacaagag cctcatcatt
     3181 tacatattgg tcaagtagtt taaagtctgc tttgatttga ttaggatcaa acaatgataa
     3241 ctcctttctt tgactagtaa ctaacgacgt gccagcttat catctaaggc agtaacaata
     3301 tcctgacgaa ccgacggcac agggatttct gccactaccg cacctagaaa acctcgaata
     3361 acaagacgct cagcagtctc ttggtctagt cctctactca ttaaataata catgtcctca
     3421 ggatccacct gaccgataga ggcggcatgg cctgctgtta cctcattttc atcaatcagg
     3481 agaataggat tggcatcaga gcgagcctga tctgacagca ttaggacacg actttcttgt
     3541 tgggcatcag caccctttgc tcccttaatg atatgaccga tagcattaaa tgtcaatgtc
     3601 ccgcgctcca agataacccc atgctgtaaa atatgcccaa ccgtatgttt tccataattg
     3661 gttactcggg tatcaatccc ctgaacttga cgaccacttg aagcagcaac caccttcaca
     3721 tcagcctgtg agccttgacc gatcaaatca ctatcaaagt cagcaatgac attgccctca
     3781 ttcatcagag caagcgccca atcaatagtc gcagcatgat ctaagcggcc tctgcgactg
     3841 atataggctg tcacctgatc acccaggcga tcaatcgccg aaaacttaat ctgacttccc
     3901 gcctgagcaa tgacctcaac actaatattg gcactagctg cttgggtctt gtctcctata
     3961 gactcaaagc gctcaaggta ggtcagctta ctttctttac ctgcaatgat gagcacatgc
     4021 ttgttaaagg ggacatcact atcaccatct tgcaagaaga tcccttcaat tggctgctca
     4081 atctcaacat gatctggaac atatagcaca gccgcactgt taaaataagc cgtatgatag
     4141 gccgccagtc tatgctcatc aaaggctaag gcagaaccaa aatgagcctc aagctgctcg
     4201 ggaatctcat ctagagctgt agcaaggtct gtaaaaacaa ctcccttttc gatcaattcc
     4261 ataggaagct gctcaagaac cgtctgtgtt ccgacctgaa ccagcttagg attatcaccc
     4321 aaggccataa aatctggaac agttcctaaa gcagtgcttt ctgtcaggct accatcacca
     4381 aagttccaac ggtgaaattt aacccgttca atagtaggca gctctaaatg tggcatcaca
     4441 tcaaaggcct ttaagcgcag ctcttgcagc caagtaggct cagcatgcgc ttgagaaaag
     4501 gccaatatct tttcttttgt catctatcct tccttttttc tggtaagctt ttcaatcatc
     4561 agcaaacata ctaatcagca cagctatggc gaagccttag acagccttgc agcttagacc
     4621 tcttctttat agtcaatgcc tagctcctca gcaatgcctg catagccttc tttttcgagt
     4681 cgtatagcaa gtgcagcatc ccctgatagg actatccgac catccatcat gacatgcacc
     4741 aagtccggag tgatgtaatt aagcaagcgc tggtaatggg taataatcat cgcaccaaat
     4801 gcctgaccac gcatctcatt aacccctttt gacaccacct ttagggcatc aatatcaagc
     4861 cctgagtcaa tctcatctaa cagcgcaaac ttaggctcta gcatgagcaa ttgcagaatt
     4921 tcatttcttt ttttctcacc gccagaaaag ccttcattga ggtagcgctc tgccatttcc
     4981 tccttcatgc caagcagggc catcttctca tctagcttgg taatgaagtc acgaacagaa
     5041 atcttatccc tgtcctcttt ccctgcattc atagcggctc gcataaattc ggcattggta
     5101 atccctggaa tctcagacgg gtattgcatc gctagaaaaa gtcccagtct agcacgctca
     5161 tcaacctcta gctccagaat attgacacca tctagtaaaa tctcaccctc tgtcacttga
     5221 tagttgggat tgcccataat cgctgctgac agtgttgatt ttcctgttcc atttggcccc
     5281 atgatagcag caatttcacc tgtccttagg gttagattga ccccctttaa aatctcttta
     5341 tcctctatcg aaacatgcaa attgttgatt tcaagaattg acattgtata cctcatcatt
     5401 tctattaggc tctttcagta tcttctttcc tgaaaatagc ctaatgcttt cattatcttc
     5461 attataacaa aaaaagcctc agcaggcttt ttacttgtct gaaatcattt cctttgcttc
     5521 cattttgaaa gcgtcgtctg acggtaatcg ctattaccga taaacttcaa gaggttgaat
     5581 aggggcgttc gtttttctcc ccagatttca ataccttcaa taaagacctc tagggcaaat
     5641 aagagtccca agataagcaa gaccccacca atacgactag agacattcaa caaaagagag
     5701 atcaaggaaa agagcatagc aataccgtaa acaaccagca ctgcaccgcg atgtgtaaac
     5761 cccattgaca agagacggtg atgcaggtgc atcttatcag gctcgtaaaa tttctttcca
     5821 gacaggcttc gacgaataat cgccacaatc gtatccataa ttggaacacc taaaataata
     5881 accggtgtaa caacggctac cgcagttgca tttttcaagc cctgcaatga taacacacca
     5941 atcataaagc cgataaaaag cgctcccgta tccccaagat aaataatagc cgggtgatag
     6001 ttatagggaa aaaagccagc aatagatgca atcaggatta aaatcgtcag ggttaaaaag
     6061 aaatttgtca atggcaaaaa gaaataagct acaatagcca ttgttactaa gctaataatc
     6121 gaaacaccac tgactagacc atctaagcca tcaataagat taatcgcatt ggtaattgag
     6181 ataatccaaa gaacggttaa aaagaaggtc aagaaaggat caaaagccag caagggtcca
     6241 ccaaaaggaa tcttaaagct atcaaattta aagtcagtaa aggcccagac aataatggca
     6301 ccaatgacaa ttcccagcat tttcagctta ggacttagct catacacatc gtctataaag
     6361 cctgttatgg taaccaccaa gcctcctaag acaactggca aaatatactg aaaataggtt
     6421 tgcccgccaa tatgagcacc atttgatgcc agaggcatca gtaccagact cgcaatcaca
     6481 aaggaagtaa agatagccaa gcctccacta gtcggcatgg gaaccttatt aatccgtcta
     6541 gcatttggag tatctaccac accgactcta atgcttagaa aacgtacaat tggcgttaat
     6601 aaaagtgaca tcagcaaggc accaattaaa accaagacat catctatcgt gaacgaaatc
     6661 atcataccct accccaacct gattttttgc agctcctcaa cagcaccatc aaaaatgagc
     6721 tgacaaccat gctcctgcaa ataagctctt gtttttgttc caggactagc atgctcaatc
     6781 aatctggcat acatcacgtt ggcaaagtag gcaggcttgt tttgcacatc aagtaaaatc
     6841 gtcatgtgat aatgacgagg acccttatac aattcagaag cctcgatcgg aaaatcaatc
     6901 accttagcaa agcaaacagc gtctcgaaca gaagcaaaat caagaacata gtgaacataa
     6961 tcaagtggct ctgtcggctc atcaagctca gcagcttcct tactatctgc ttgctcagcc
     7021 aaggtagcat caaccacgtc ctccatgatc tcctcgattt tttcaagctt ttcatgggca
     7081 ttgacatcac ccttttcacg catagactgc tccaagcttc tgaaaaaatc ctctggagtc
     7141 atttgagaaa tatcacctag gtctgccaaa tcctcaaaat taaggtcctt attgaggtct
     7201 gatttggtca caaaaacatc taagcgatcc tttcttggag tcactcgaaa gctaagcata
     7261 ccactgtcct taaaattgtc cggaaggccc aactcgtcca tgacagcata aaagaactcc
     7321 tctgtctttt cttgagggat caagaagtcc ttgagctcca tccccctttc ttctaaatcg
     7381 tccatactaa ttgttatttt tagcgttgtc tcgctaattt gtttcatttc cattgtaaaa
     7441 tacctcgcag gcgtagtcat tttattatac tagaaatact atgatttcgc aatttatgac
     7501 tagccttaca gcaagtaaaa gcagccttcc taggaaaact gcctgacgat ttctaaaaaa
     7561 gtgacttaaa tacactgtag acaatcaata agcttcccaa cacaatccgg taccgcccaa
     7621 agactgtaaa atcatgcttt ttaacataat ctgttaacaa tttgatcaca tacaaactga
     7681 ctgcaaaggc tgttaggctg gcaactaaaa gcactaatag ctgcgagagg gtcaaatggt
     7741 tgccatcaat aaaaaacttc aaagctttta ggccactata gccaaacatc gtcggaatgg
     7801 ccaaaaagaa ggtaaagtcc gcagcaactg tcctgcttgc tccaagaata atcgccccta
     7861 aaatcgttgc tcccgaacga ctggtcccag gaataatgct aagcacctga aagcagccaa
     7921 taaagaaggc tgttttatag gacatacgag atagcttgac gactcgcggc tcaagtgtct
     7981 gatttctctt ttcaatccat aaaaaggcta tcccataaac aatcaatgca atagcaatag
     8041 gaagcatatg attaaaatga gcgtcaaacc aatcatcaag tggtactgca atgataatag
     8101 acggaataca agcaatagca accttaagcc acagctgcca ggttagcctg atttgctgtg
     8161 ggctcttgcc aggctgaaaa gggttcaagc gttcaaagta aataacaata accgcaataa
     8221 tcgctcccag ctgaataaca atattaaaca tctccataaa ggccttatcc tgatgaagtc
     8281 tgataaattc ctgaaccaaa atcagatgtc cagtactgga aataggcagc cactcagtaa
     8341 ctccctcaat aacaccaaag aagatggcct tcagcaattc aataaataac atgttccctc
     8401 cttctaacaa agactctcat atctagcccg tcctaaaaga acaccacttc ctcctccatt
     8461 gccagcggag aagccgcaac cacagtcacc aagcaacagc aatggggtat tgcttttttt
     8521 gcttgttcat attgtaccat aaatgacacc gttaataaat cagtgacttc ataagaaaaa
     8581 gcttattttt aatcatttct tcacttgttt tatgaataaa taatcacctc ttttaaccaa
     8641 tgtattgaaa tagcttgtaa attactatag aatagtatta aacacgtttt taaaaaagga
     8701 gacctatatg aaaaagctag tccttagctg cttggccacc ttacttattt ttcttggagg
     8761 aataggtact gtgcaagcag atcactattt acgagttggt atggaggcgg cttactctcc
     8821 atttaactgg actcaagatg attcgtcaaa tggcgctgtt cctatcgaag gaaccagcca
     8881 atacgccaat ggctatgatg tgcaaatcgc taaaaaaatt gcaaaagcat taaacaaaga
     8941 cttattggtt gtgaaaacct cgtggacagg tcttattccg gctctgacct caggtaagat
     9001 tgatttaatt gcagctggta tgagcccaac agcagagcgc aaaaaagaaa ttgccttttc
     9061 taacagctac tacaccagcg agccagtcat tgttgtcgcc tcaaatggta agtatgccaa
     9121 ggctcgttct atcaaagatt tttcaggtgc taaggtaact gctcaacagg gcgtgtggca
     9181 tgtcaacctg ctaccacagc tagagggggc aaagcttcaa acaccaatgg gagatttttc
     9241 tcaaatgcgc caggctctaa cctctggagt gattgatggc tatatctccg agcgccctga
     9301 ggcaatgaca gccgagactg ccaacaaagc ctttaaaatg atcactctaa caaaaggatt
     9361 taccgtttca gagtcagacg ctgccattgc cattggcatg aaaaaaggag acgaccgcct
     9421 tacagcagtc aatcaagtgc ttgatgccat ttctcaaaag gaacgccttg ccttgatgga
     9481 caagatgatc caacagcagc caagcgagcc caaagctgat gaagcaaagc cctcctttat
     9541 caagcaaacc tggtcaatct ttcaaagcaa ctggaagcag ttccttcgcg ggacaggcat
     9601 gaccctcctg atttcgatga ttggtactat cacaggactt ttcatcggtc tcttgattgg
     9661 tatttaccgt acagcaccaa aggctaaagg caaattggca gcgctagctc aaaggctctt
     9721 tggtggacta ctcaacgtct atatcgaagt ctttcgtggg acgccaatga ttgttcaatc
     9781 aatggtgatc tactacggca ctgcacaggc ctttggcatt tccattgacc gcacactagc
     9841 agctatcgtt attgtctcaa tcaacacagg tgcttacatg agtgaaattg tccgaggcgg
     9901 tatctttgca gttgacaaag ggcagtttga agcagcaaca gcccttggct ttactcatgg
     9961 gcaaaccatg cgtcagattg tccttcctca ggtggttcgt aatatcctac ctgctactgg
    10021 taatgagttt gtcatcaata tcaaggatac ctctgtcttg aatgtcattt cagtggttga
    10081 gctatatttc tcaggaaata cagtggctac tcagacttat caatacttcc aaacctttac
    10141 cattatcgct attatttact tcgtcctaac ctttacggta acgcgtatcc ttcgctatat
    10201 cgaacgtcgc ttcgatgctg atacttacac taccggagca aaccaaatgc aagtttcgga
    10261 ggtcccaaat gtctaatccc attattgaaa ttaaaaacct aaaaaaatct tacggcaaca
    10321 atgaggtcct aaaggacatc tcgctaaccg tcaataaagg agaggtgatt tcaatcatcg
    10381 gttcatctgg atcaggcaaa tcaaccctcc tacgctcaat caacctatta gaagagccta
    10441 gcgccggaga aattctcttt catggtgaca atgtgcttgc agaaggctac aacctgaccc
    10501 attaccgtga aaaattgggc atggttttcc agtccttcaa tctctttgaa aatcttaacg
    10561 ttttagaaaa tgcaatcgta gctcaaacaa ctgtcctcaa gagagaacga tcagaggctg
    10621 aaaaaatcgc caaggaaaat ctcaaggcag ttggcatgac cgagcaatac tggcaagcca
    10681 agcctaagca gctatcaggc ggacaaaagc aacgtgttgc tatcgcccgc gccctatctg
    10741 ttaaccctga agccatgctg tttgatgagc caacatcagc tcttgaccca gaaatggtcg
    10801 cagaggtctt aaaaaccatg caagatctgg ctaaatcagg cttgaccatg attattgtca
    10861 ctcacgaaat ggagtttgca agagatgttt ctgaccgtgt cattttcatg gataaggggc
    10921 tcattgcaga agaaggcacg ccaaagcagc tctttgagca gccaaagcag gaccgaacca
    10981 aagcattttt acagcgcttt ttgtcataag cctaaaagcc agtctaacca taggtgttag
    11041 attggctttt tttgataagt cacatctgct aagcagcata atgatcatat agactacttt
    11101 agatcaaaga aaagacctat tataggacaa tttccctcaa caggcacaga taataaacct
    11161 ccttttgaag gttgtgctgc tactttttca aagctgctaa ggcaactggt ctacaaaaat
    11221 catttctcaa atgagacggt aactgttaag cttgatctct attctaaaat ttcaacacaa
    11281 aatactttac tggttaataa ctttgtgcta tactgtcttt attaacgtta ataatatatt
    11341 ttagtaggag gatagcatgg ccgaaaaaac tgacctcgcg tcagcttaca gaagactaaa
    11401 aagcccaaat attaaaacta aaaaacgtgc tctgaagatt attcacgagc acaaacgtta
    11461 cggtaaaaaa tagtattcta tttttatctc tccaaattta agtcagataa aaaatgatta
    11521 ggacaccatc cctccgtctt aatcattttt tgatggccaa gaaaagaaag ctttaagcat
    11581 tgttaaccat caacaagctg aggacacaca catctgatag agctgccaat agtagcagtt
    11641 aggaaatgct acactcagct tttaggtcca tgcttcagca ttttcaagca accggatacc
    11701 aagaaaacta accttttagc acagcacaaa gcggcacttg aactcacttt gttccctcat
    11761 ttgctctctt agcggctaag cttcaaaggt gattgaaaca acccattgca attggtctag
    11821 cttccaagct gtttgagcct gtgattcttg ctagcatttc agacatagca acatttttca
    11881 atagccatta tgcttaagac aatagtgaaa taaagacgac tgccttactt ttcaagaaca
    11941 ttgacgagcc atcatacaaa aagcaagctg atgctgacca gcttgcttaa tatatattat
    12001 cttgttttta aggctgatag cacctgagtg cgaatatcat caacaccatt tagagtattt
    12061 ggtaggaaaa gggtctgatt accctttgca gcaaaggtat tgagggtatc taagtactgg
    12121 ttggtcagaa gaattgacat gatctgctct tcattcagtg aaatattagc ctccttcaat
    12181 tcctgaatag aatcagccaa gccatcaaca atagccttac gctgctgtgc aataccaaca
    12241 ccatgcaggc gatccttttc ggcttccgct tctgctgcag ttacaatttt aatcttatca
    12301 gcattagcca attcctgtgc tgccacacgc ttacgctgag cagcattaat ttcattcata
    12361 gactgcttga cttcagcgtc tggctcaacc tttgtaatca aggtctttac aataatatag
    12421 ccataggttg acatttcttc tgctacctga tgctgcacct ccaaggcaat ttcatctttt
    12481 ttctcaaaca attcatctaa ggttagcttt ggaacagaag agcgcaaggc atcttcaata
    12541 taagacctaa tttgagcctc tggcttgatc aatttgtaat aagcatctat cacattttgc
    12601 tcattcacac gatattgagt cgcaacattt agcgtcacaa aaacattgtc cttggtcttt
    12661 gtttcaacaa taatctctga ctgcagcaaa cgcaattgca cacgcgcagc aatgcggtca
    12721 atcccaaagg gcaatcgaat atgaatacca ctagtagctg taccttgata tttaccaaag
    12781 cgctctataa tagcaacaga ttgctggcgc accacataca gcgtgcttgc cataatggat
    12841 aatatcacaa tcaccagaaa tccaataatc aaaatagctt ctaacatgtt aatctcctcc
    12901 ttataaagcc ctagctggat agctatacgg ctttttatga ttgcctcatt gttataagac
    12961 aattataaaa catttttgtc ttttgtcaat aaaaatctca acgtctatca gccggcttta
    13021 cagctgctag agaccactaa aagtctacac ctgacgacag gctgcaatca ttgcttctta
    13081 atagtcaagt cttccttcca aagacaaaag gagctaagcc ttgcctaact cctctctttg
    13141 ttctattcat tattcaacac tcataaggta tggatacaca ggctgatctc cctgatgcaa
    13201 ctcaacctct atatcctcat atgtttcctc gaggtaatca gcaagacctt gagccacttc
    13261 actgctgcca tcctcaccaa tgaagatcgt aacgatttcg ctgtcctcat caatcatgtg
    13321 atcaaaggta gtctttaggg tagcttccat gtctggattt gacactacaa tgctgccatc
    13381 gaccattcct aaaaagtcat tttcatgaat atcaaggcca tcaatcgttg tatcgcgcac
    13441 agccagagtc acacttccac taaccacatc agacaggctt gctgtcatat cagctacatt
    13501 atcctccaaa gtttttgaag gatcaaaggc cagcaggctc gtaaagcctt gtggaattgt
    13561 acgtgtctcc acaacagccg caggaatatc cacaacctcg gctgctgatt gggctgccat
    13621 gaagatgttt ttattgtttg gtaagataat cacctgctta gcattgacag cttcgatagc
    13681 cttaacaata tcctcagtag atggattcat ggtttgtcca cctgagataa cgtagtcaac
    13741 cccctgtgcc ttaaaaatct ctgccaggcc atcacctgca acaacagcaa tcaggccaaa
    13801 ctcttttgcc tctgccttag taggctcatt gtctattttt tgtacctgtg cctcatgctg
    13861 attgcgcatg ttatctactt taattttgat cagtgagccg tacttcagac cctcttgcat
    13921 cactagccct ggatcctctg tatggacgtg aaccttaacg atctcatcat catttactac
    13981 taaaagcgaa tcaccaagcc cactcaaata gccctgaaat tcatcataat taaattcttt
    14041 aacataggta ggaccctgct ttagagcaac cataatctca gtacaatagc cataggtaat
    14101 atcctcggta gcaacatgac ctgcaactga tttgtggtgc tcagccttaa tcatctcaga
    14161 catattggca ggagtggcct taaagtcctc agaagctaca taatcaccat ttaaggcaga
    14221 caagaagccc tcgtaaataa agacaagacc ttgacctcct gagtcaacaa caccaacctc
    14281 ttttaaaact ggcagcaggt ctggtgtttt tgcaagggct ccttttgcac catctagcgc
    14341 tgcttgcatc acctcaatgg cattatcagt aaggtctgcc tttttcaagg ctgctgttgc
    14401 tgcaccacga gaaacggtca aaatagtccc ctcaacaggc ttcatcaccg ccttgtaggc
    14461 aacctcaact cccatctgaa aggcctgagc taaatcctta cctgtcagct cctcttttga
    14521 cttgatactt tggccaaagc cacgaaaaag ctgcgaggta ataacaccag aattgccacg
    14581 cgcccccatc aagagaccct tggataggat ctgcccaacc tcaccaaccg ttgaagccgg
    14641 cttatcagca acctctttag caccattatc cattgtcatg ctcatattag tccctgtatc
    14701 accatctggt acaggaaaaa cgtttaagga attgacatat tctgcttgtt taccaagacg
    14761 agttgctgcc gcttggacca tttcttggaa taagcttgtt gtaatatttg acactaattt
    14821 tctcctacaa ctttaatatt ttgcacgtaa acattcacca tatccgcaga aagcccaagc
    14881 tgactctcaa ggttaaattt cacacgctcc tgaatatttt tggatacctc actaatttta
    14941 acaccgtagc tcataacagt atagacatca actgaaatac ccatgtccgt tgacttaaca
    15001 actacaccct tagcataatt ttctttgcga agtagcgatt gaaagttatc ttttagagca
    15061 cttttactag ccataccaac aacgccaaaa atttccgttg ctgaacctcc aacgacagtt
    15121 gcaataacgt catcagatag ctcaattaga ccatcttttg tattaatttt tacagtcata
    15181 gttactacct caaaaagttt ttatcagctt attttatcat aattcaaggt caatgtaaaa
    15241 agatataagc gaagaaaggt cacctctatc atgcttttct aagctttttc tgaaaacgac
    15301 taagaaaaaa agccctaagg cttatttcga ttagatgcgt tctactttac cagatttaag
    15361 cgcacgagct gaagcccaaa ctttttttgg tttaccatca acaaggatag taactttttg
    15421 aagatttggt ttaacagtac gttttgtttg gttcatagcg tgtgaacggt tgttaccaga
    15481 tacagtctta cgacctgtga aataacatac tttagccatt gtaatctatt tcctcctagg
    15541 tagaatatgt ttacggatgt gctagcacca catacttacc tagtctatca caactcttac
    15601 cttttggcaa gctatttttt acatctgcag gccttagcca ctaagcagca aaatgtccct
    15661 cttaatagct aagcactcac ttgctcctct cctataaata ggtctataag aatcaataat
    15721 accctatcta tcacaaatgt ctaagggctg ctgtcagctc gaaagccttc tcttagaacg
    15781 ctaaaactac tctaagaaat agaggttatt taacaggctt tgctgtagtt gcctagctga
    15841 aatcctataa gcatgcacta aaaaagacta aacaagacat cacacaacca cattagtagg
    15901 gagattagcc tgaggagtgc ttcttgttta gtcttttatc ctcttgaaag ccttgatcag
    15961 tatcgtgatt gctgatttct aatcacgctt ctctaactgc tcaggtgtga agtggtcaaa
    16021 ctgggcaatt aaaaaatcaa tatactcttc aaggtgtaaa agcttataga gaaaaacgtg
    16081 gctattaatg gtatcaatat aattacccat aataaagcca tctaaatcag aatctttaat
    16141 cttcttgatt aattccttct ttttttgttc aacctcttca tcagtgcctt tattttgctg
    16201 agacaggtac caggacctat tccaataaaa ggttgataca tgcgcaaaag ctgtccggct
    16261 agtaccgact gctaaaccaa gacaaacaga tagtagtcca aggcccttta aaagagactt
    16321 ttttgaaata cttagatctg ccatagcgag tcctcctttt tatttttcta accaaaccat
    16381 actaaaatat aactatattg taaaataaaa agtattgtat tagaaataag taaaaataaa
    16441 gctatgaata gttgacctaa ctaaacccaa caaataagat gctacatgac aaaattcctt
    16501 ttattctcac cacctgtgat ctcatcaaaa gctctctaaa ccagagaggc atagacagct
    16561 accgaatgaa gccttagtaa tagctgtctc agctcacctt aaactaatag ggtcgataaa
    16621 taaggagaca tttgcgcagc agaagctgat agtgtcaaag gttctacttc agcaagcata
    16681 tcatgagtca cctatttcag cacaggcttg gtaatgtttg gatagtacaa agcgtttttc
    16741 tcaagaacgt tcaagatcct tccagtcata gcagagcagc ccttaccaca gacatctgct
    16801 agcacacacc tcaaaaacaa agacataatc gctcaagtag ggctattctt tatcggcaag
    16861 gggattaggc gaaggaacta taaaaaggcc tatccttgcg gataaaccct gatttaatca
    16921 cgtttagcag tcattaagcc ttgtttgctg agccaaagac atcaatacgt tcttcaacag
    16981 aagcctggat cgccttaaca ccatctgcca agaatttacg tgggtcaaag agttttttct
    17041 tatcgtattc tgcaacgttt gcttcgtaat cacgcgcaaa ggcacgagta gcgttagcaa
    17101 atgcaatttg acactctgta ttaacattaa cctttgcaac accaagcttg atagctgctt
    17161 gaatttggtc atcaggaata cctgaaccac catgaagcac gattgggaag cctggtacag
    17221 catcagtcaa tttcttcaag tgatctagat caagaccagt ccagttttct gggtatgggc
    17281 catggatatt accaatacct gcagccaaga agtcaattcc tgtagcaacc attgccttag
    17341 cgtcttcaat cggagcaagc tcaccactac cgatgatacc gtcttcttca ccaccaattg
    17401 tacctacctc agcttcaact gaaacaccct tagcatgtgc tagcttaaca atttcacgtg
    17461 ctttctcaag gttttcttca actggaaggt gtgaaccgtc aaacatgatt gaagtgtaac
    17521 caacctcgat acattcaaga gcatcttcat agtgaccatg atcaagatgg atcgcaaccg
    17581 gtacagtgat gttcattgat tctacaagag tttcgataag aaccttagct agcttgtagc
    17641 cacccatgta tttagctgca cccattgagg tttggataag aacaggagct tgtttagctt
    17701 ctgctgcacg caggatcgct tgagtccatt caaggttgtt tgtgttaaat ccaccaacag
    17761 catagccgtt atcacgtgct gcttggacaa atttttctgc tgaaacgatt ggcattttaa
    17821 taagcctcct cttatatttt gggttaaccc catttacatt gttcatttta gcacaatttt
    17881 caagaaattt ccagcccctc atcagcttaa agcgttttct cgattcatct tatcacaggc
    17941 tcacaattga gcatttggct agcagcagtc ttttcaggaa ataaaaaaaa agatgaatcc
    18001 aagattcacc tctgcgatgc ggagagtggg acttgaaccc acacgaccta aagcggtcac
    18061 aggatcctta gtcctgcgcg tctgccaatt ccgccatccc cgcttgctct ttagcaacat
    18121 ataaaattat atcagctggg agctttactg tcaatactta tttctcatat ttttgcaaaa
    18181 aggccgcaat cttttccttg tactggtcgg gattggtctc aaaggacttg gcatgcttag
    18241 cccccttaac aaccattagc tctttaggac cttttgttgc ctgatagttt tgatagacca
    18301 tctctgtcgg gacaaaggta tccttgtcgc catgaataaa gaggactggc agcttatttt
    18361 tggccaattg cttcaccgag ctagcctcac catagctaaa gccggcacga attttagaga
    18421 gggctgaaac ctcatacagc aagggaaagg ctggtagatt gtacatggcc ttagcttgga
    18481 atttcaattc gtcccaaaca ctagtatagc cacaatcctc aacaatattg acaacctgac
    18541 taggtagctg ctcaccgctt gccatcataa cggttgcggc acccatggat aagccaaata
    18601 agctaatgcg actgccttta tcctcgctaa cgagcaaatc aatccaggca agtaggttca
    18661 agcgatcatt ccagccatag ccaatcaagt caccctcact ctcaccatga gcctcattat
    18721 ctggtatcag cacattgtag cctaggctgt gaaaaagcat ggcatagggc ttcatgtcct
    18781 ctttatcatt tgtaaagcca tgaacgacaa tagctgtctt atgagtatcc tgcgaggcag
    18841 gcaaatacca tgcaacctgt tgacgtcctc tgttagtgat gctgcgtttt tcacgcgtca
    18901 agctgtcaaa agctagctct gctgggtaca aaggattgtc tggggttcgt tttttattgt
    18961 tgataaatga cttttcctca cgcacctgag caacatggaa gaaataaaag ctagctccca
    19021 cactagccag ggtcaacaag agcagtaaaa tgccaaaata ctttgataat cgaatggttt
    19081 tcataccgac tattctacaa gaaaatatgg aaaaaagaaa gctttatgct aaaaataacc
    19141 gatacctttt tactgccttc ttaaggccaa atctcaagcc agccagtagc taaagcgttt
    19201 tcgcaggaat tgaagctcaa tagtttaaag aatatacaag ctaccttcaa aatagctttg
    19261 accagatcaa gaggaagtcc gctgacagca tttgataaga ggtaaaatgg tgctttttgc
    19321 tatattaaaa gtggctgatg tcatcatctc atcagccact caaagactta ataagcctat
    19381 caaagctgct aactctcagc acctaaataa ggctcaagga tagcctctta cgtcatacta
    19441 gacttaaagg ctttggtttt tatttttcac tgctgctgta acaaaggcag tgtatagctc
    19501 ttcaggacga ttaggacggc tttgcagctc tggatggtat tgggctgcca caaagaattt
    19561 cttctctggt aattctacaa tctctaccaa acgattgtcc ggcgaaacac ctgagaaaac
    19621 aaagcctgct gcttcaaagt cctgacggaa tttattgtta aattcgtaac ggtggcggtg
    19681 acggcgctgc accacctctt ggttattgta ggctgctgca gctcttgagc cagcttttag
    19741 cttacatggg tatagcccca gacgtaatgt tcctcccatg tcctcaatat caatttgatc
    19801 acgcataata tcaatgattg gataggcagt atctggatcc agctcaaacg aattggcctt
    19861 ttccatgcct aggacatgac gagcaaactc aacacaggtt aattgcatgc ctaagcaaat
    19921 gcccagcatc ggcacatcat gctcacgcgc atagcgaatg gcttgaattt ttccttctgt
    19981 tccacgctga ccaaagccgc caggaacgat aatgccatca gcctgcccaa gcagcttctt
    20041 agcgttttca gctgtcaggt cattagcatt aatccaatca agctcaatag cagtgtcatt
    20101 agcatagcca gaatgcttta gggcttccac aacagacaaa tacgcatctg gaagctcaac
    20161 atatttccca accaaagcaa tccttgtcgt tttcttgagg ttcatcactc tatcaaccat
    20221 agctgaccat tctgtcatat ctgcctgagg cacgtctagc ttcaagtgat cacagacgat
    20281 ttgatccatt gattgagcct gcaaattcag tggaatttga tacaaatgct ccacgtcacg
    20341 agattcaata acggcttctg ggttaacatc acaaaattgc gccagcttat tttttatccc
    20401 ctgctcaaca ggctcctcag tacgaatgac aagcatattc ggctgaatgc ctaagccgcg
    20461 taattcctta acagagtgct gtgtcggctt tgttttcatc tcgcctgctg cttttaaata
    20521 aggcagtagg gttgtgtgaa tatacatcac attttcagag ccgacatctg ccttcatttg
    20581 acgaagcgct tctaagaatg gcagactctc aatgtctccc acagttccac caacctcggt
    20641 aataatcacg tcagaatctg tggtcgtagc tgcgcgcttg atcttctcct ttaaggcatc
    20701 tgtaatgtgt ggaataacct gaacagtcgc tccaaggtat tcacccttac gctccttacg
    20761 aagcacctca ctgtagattt taccagttgt cacatttgag tatttattaa gattaatgtc
    20821 aataaaccgt tcgtagtgac caagatccaa gtcagtctct gcaccatcat cagtgacata
    20881 gacctcccca tgctgataag ggctcattgt cccaggatcg atattaatat aagggtcgaa
    20941 tttttgaatc gttaccttta ggccacgatt tttcaataaa cgtccaaggc tagccgctac
    21001 aatacctttt ccgattgatg agaccactcc gccagttaca aaaatgtact ttgtcataac
    21061 actcctttat ccttttgagt taagcctgac taactcgttt ttatttttaa aagatcgtcc
    21121 tactttagct agtaacgatt gggggctaag cttcccataa ggctaagcca tgagaccagt
    21181 aaccaaggct aagttattaa aacaaaaata gccccctatt aactagggag cttacctgac
    21241 ctcttaaaga ggtgcccgat taataatata aactataaga ggacatttgt caaatattac
    21301 tgttgctttt agaggctagc gatactcctg ctattcctcc tcttcctcat cttcttcgtc
    21361 ctcttcattg aggtcaacct cttcaaaatc gtcctctgga atgatttcat tgagctctga
    21421 atcgtaggac tctacttcag atttttcatc gtctggatct tcctcgtcat attcaatatc
    21481 agatgattca cgaacaaaat cctcatcctc tggatcatca gcgctatagt caatagcgtc
    21541 ctcatcaccg tccatgaagg cattgacacg tttcttcttg cgttttggtg cgccgtcttc
    21601 ttcatcttct agggtgatga tttcctcatc aatctcatca atagcatacc atgaacgtag
    21661 accccattta ttttcaccaa gtggaataaa gctaccatct gtattgagat cagtgtaaaa
    21721 aaatggtaaa gcatatcgaa tatcagcgtc agacttgcct aggtaatttt gaatctcatt
    21781 aaccaaatcg ctaaaataca tgtcattatc gcgaccacgc tcttctaaaa tagcacgagc
    21841 aacttcaatc atagaaagtt cgcttatttc ttgtcctgca aatacatcta atttcaaggc
    21901 agttctcctt attttatcat tctcccctat tttacgctaa aaataccgat tcgtcaaagc
    21961 ttttatcagg gaagaacagt attcttttta cccacttctc agccagcaag aacaaagcct
    22021 agcagcaacc agcttgattg ctcctaaacg cgataacaga agcatttcaa agagaagtgt
    22081 taactgtttg cctttaaacc atgaagcaac agcaaaacaa gaccaagtgc ttgcttagtc
    22141 ttgcttgtct atatcataac agcttatttt gcttttgctg agcttgtaat cacttctaca
    22201 gcttttttca taacaatgtc atgctttaac atatcagctg aaagcaatga gcgaacctgc
    22261 tcaactggca tgctatactc agctgcaagg tcgttaattt ctttttcaat ctcatcgtct
    22321 gaagcttcaa agccctctgc ctttgcgata gcctcaataa cgagattagt tttgacacgc
    22381 ttgtctgcct ctgcttcatg ctgcttgtga agatcttctt gacttgtgcc agttagctgg
    22441 aagtacatat caggtgaaat gccctgacgc tgcatgctag ccataaattc attaacggaa
    22501 cggtgaacct cgtcatgaac catttcctct ggtaattcca caatttcagc attctcaaca
    22561 gctaactcaa tagcagcacc ctctagagcg tcatcataag ctgcttcctt tgaagcctca
    22621 agctctttac gatacttagc ctttagctca tcaagtgttt caacttcctc gtcaatatcc
    22681 tttgcaagct catcgtcaag ctcaggtact tcttttgcct ttacctcatg aacagttgcc
    22741 acaaacttag cagccttacc tgcaagatct tcagcttgat aattttctgg gaaggttaca
    22801 ttaacctcaa cagtgtcacc agccttagcg ccaactagct gttcctcaaa gcctggaata
    22861 aattgtcctg agccaagctc aagtgagaaa ttgtctcctt tgccgccatc aaattcaact
    22921 ccatcaacag agcctacaaa atcaataaca actgtgtcac cttctactgc tgcttcttct
    22981 ttgacaacca gctcagcaag attgttgcgc tcgcgctcaa cctttgcgtc aacctcctca
    23041 tcagtaacct cttttgaagc ctcaacctca acagtaaggt ctttgtaatc accaagctta
    23101 acctctggtt ttgtgacaac ctctgcagta agtgtccatt cttgacactt ttccatagaa
    23161 accacatcaa tttttggctg tgcaacaaca tcaagctcaa gctctgcaac agcaccttca
    23221 taggctgctg gcagcacaat attcaaggcc tcctcataaa gaacctcttc accaaatctt
    23281 tgatcaaaaa caggacgagg catgtgaccc ttacggaagc ctggtgcatt taaatccttt
    23341 ttaattttat taaaagcttg atcaagagcg ggcttgattt tatcttgact aatggtaaat
    23401 gtaatcacgc cacgatttgt agctttgttc tcaaatgatg tagacattaa gtcatttctc
    23461 cttaaaataa tttagataca cctcattcta tcatattacc aagtgttttt aaagtttttt
    23521 atgcgtgaaa gtagggacag ggtttccaaa tatcagactc ttaactgaac cattaccaaa
    23581 aacctcatca gcttcaaaga aaaagagact ggaacaaaag tctgcctcca aaataaaaca
    23641 aacgaacaag acttgttttc tgagatccca aaaactagtc ttgttcgctt tttaattatt
    23701 tagactgggt aataaaatac attagctaag actttttaac atgcaactct ttttgtccca
    23761 gagtccaaac agtccttaat ctgtaagcca gatagttacg ctggaagtag gacagctact
    23821 gatttcttag ctagatgacc ggtaatgttg tgattggaaa catgataaac tgtgccagtc
    23881 actgcgtctt tgtagtcacc gtcagctagg gttgttgtag aagaaaagtc tttatcaacg
    23941 atggttaggt tggtgataac agcacccttt tgaccgcgtt caatcatgac tagaccttgg
    24001 tccataccag gattgcgaat atattctgat tgaccattca tcctattgcg gaattgatta
    24061 atcgcaacaa tggttggatc cttaaacaag tcactgccgg catcaccaat ttggctttct
    24121 ccagggaagc gtccattttg gccgccaccg ccacgaggac gtgaaaagaa gagcggtgct
    24181 ccctcattac gagcagcaat aattccccag ccaagcttaa tgtcctcatc tgttagcttg
    24241 gtagactctt catcatcgtt agcataggta tcatgagatt ctacccaagt gactaacttg
    24301 tcctctgaaa cgccatgcac ttggaaattc accaaatccc aatctttcac atagccttga
    24361 cctagcactt tacggattag cttaccatag tttgacgctg tcactcccat gatattgcca
    24421 tagcctgctt cgttgcaagc atcaccctgt aaaatttctc catattggaa tttagcacca
    24481 ttgttaagaa taaccttcca gaaatcgctg ttatgctcac ctggtaattc gatatgcttt
    24541 gcagcatcat acctaaagcc atctgctcca tcagctactg ctcgttttag ataattcagc
    24601 atgtattctt ggacagctcg attttgcgtg ttgaaatcat aaagtcctag caaggatttt
    24661 tgggttattt gataacgatc gttgaagttg acgattttgt catttccatg tgtccagtta
    24721 tctatggctg tgatcttagg gctaactgcc ttaatctcag aggttgtatg attcaaaaca
    24781 gcatcaacaa taatattgat cccatattta tcagcctcct gagccattgc cttaaattcc
    24841 tcttctgttc ctaattggta gttcccgata gtatagtctg ttggctgata atggtaatac
    24901 cagtttttca agtccttact accgccagct ccttcaatga cagcattaat aggtgaggtt
    24961 tgaatactag tgtagccagc ttccttaatg gcactcatgt tttctttgat ggtgttaaag
    25021 gaccagcacc aagcatgtaa aatagctccg tccttcatgg ctaccggttg attatcggac
    25081 tgcacctcct gagcactagc aaggttagct ggggctagag gagccaagcc tgaaagtacc
    25141 aagccaaggg tcaagctggt cactgataga gctttgagaa atctttttgt cttatgtgtt
    25201 accatatgta aactccgttc tttctgcgaa atcgctttcg ttggtgctta aaaaaataag
    25261 atgattctct gtactgtttg caaacaaaaa taggacctat gagagaagta taacatataa
    25321 atttcggtat gcataccatt tttagcaaaa aattagtgat ttttttaatt tttatttcct
    25381 ttgctaaagc ctctaaaacc aatcaaaata atgttgcata agtatttgcc ttttatttat
    25441 ctcataatca gactcattcg ctctaatctt ttgcacatgt taatgtcatt tatttgcaga
    25501 cctacgcaac caattgcaca gagctttgtt tccttcgtca gaaaaacctc aataaaacat
    25561 aaacaagaag ccattactct tcttgataat gtttggtgat ctattttcaa ccaggacttt
    25621 ttttggtaaa ctagctacga tagaaaggag ttgccatgac gtttatatta acatacttta
    25681 atcagctaca cctagaaaat atcatggtgc ttgtgttttc taaattagtg tcaatcacct
    25741 tattattgat tttctttgtg atcttcaaaa aaatcacgac agctttattt gaaaaggcaa
    25801 tcgccaagtc attttcctat tcaagacaaa ctgaagcaag gaaaaaaacc ttatccaagc
    25861 tccttcacaa caccctaaat tatgttttct attttcttct catctattgg attttgagcc
    25921 tacttggtat tccagtatct agtcttttag caggagcagg aattgctggt gttgctattg
    25981 ggcttggggc tcaaggcttc ttgtctgatg tggtcaatgg cttttttatt ctgtttgaaa
    26041 atcaatttga agtaggagac accgtcacca ttgcaggcat tgaaggaacc atctccagcg
    26101 ttggtattcg aaccactcag gtgcgaggct ttgatggcac actacatttt attcccaacc
    26161 gcaatattac agttgttagc aacaaatcac gcggcaatat gagagctttg atcgatattc
    26221 cactttattc ctcaaccgat ctagagcatg tgacccaaat catcaaggct gtcaataagc
    26281 gagaggtgcc aaatttccca caaattgtcg gacagcccaa cattctagga ccacaaacca
    26341 atcccaacgg acaattcacc tttcgcgtta gcatttttac tgaaaatggg cagcaattta
    26401 cgatttacta tagcttttat aagctctatc aagaggcctt actaagggag ggtatcaagc
    26461 taccaactgc atctgccata tcacccttag cctagcagta aaaaccattg ctttcttagc
    26521 atacaaaagc cctatcccgc agccaggtca tcagacttag actgctagat agggctattt
    26581 cttttggctc ttatttccga ataggatcag gctgatacct ggctcttaca ccaccaatta
    26641 atttgggccg acttgctaag gcagtcacat gagcaccacc aagctctcgc tgaataggca
    26701 caagcggcac ctgtacacgc ttaacatgca taccaattga ggtatctcca atgtcaaggc
    26761 ctgcatgagc agcaatggct tcaacctcaa ctggctgctt catgtatttg aaggctgcta
    26821 attgaccact tcctccagca tgcaagctag gcagcacatt gactatttct agccgatatt
    26881 cttcagcaac actttcttct aataccaagg cacgattaat gtgctcacac ccctgaaccg
    26941 ctaaatgaat ccctctgaac gacaattcct ccaatataag cttcacaata acctcgccca
    27001 cctctaagct agaatgctgg ccaatacgac caccaagtac ctcgctagag gacagcccta
    27061 agacaaacag ttgccctttt ttgatagcac tacgctccac aatatcaagc aagatagagc
    27121 gtgcttcttc tctcaatact tttaaattca ttgaatcacc tgcttaatca tctgacactt
    27181 tgaccagctg ttttttgacc cctaaataca gcagatagcc tacacctatg ccaagggtat
    27241 tttgagcagc attccccgaa atttctgaaa tagcagcgcc cataccatac attggaatag
    27301 ctgcaagaaa atacagacca accattatca cagaagcaag gcccacgcca agaaagcgat
    27361 gcctgccagg caagcctgct aagtagccct gagccccatg agcaacaaga ctaatcagca
    27421 tccaattggg gtaacctgag atcaaatcaa gcaaaaaagc tgataagccc ccaacaagca
    27481 taccctcctt tttcccaaga gaaaaggcag tcacatacac ccctgcatct aaaagactta
    27541 aaaaacctgt cggcgtggca atactcacaa acctgcccag gacaactgtc agggcagtca
    27601 agatagacac aagagctagc tctcttgtct gtttcatatt tatcataaga caactccata
    27661 atcatttgac tgttgaatgg cttcaaaaac aaggtcttta gcctgctcaa cagccctaag
    27721 cggtgaatat cccttagcta aataagcagc aattgcagct gcaaagctac agccagcccc
    27781 actgttttgt ttggccaaga ctggcttttc taaaaagcac agggtttttg cgtcataaaa
    27841 tagatctagg gcaactcgtt gatcaaaacg attcccaccc ttgatcacaa ccctcttagc
    27901 ccccatctca taaagctttt ttgccgcttc taccatttgc tccctgctat taatagcaag
    27961 ccctgccaag cgttctgctt ctcttaggtt gggagtaatc actgctgtta agggaaaaag
    28021 agagcgcaaa gcctgtgtca tttccacaac tgtctgatct tgattttcct taaatactaa
    28081 aacaggatct aaaacaacag ggatatcctt ttttagctct aaaaacaggg ccacctgctc
    28141 tgctatttca ggtcttggca aaagaccaac tttgattgcc tgaaaaggaa tagctgctaa
    28201 gctagacaac tgctttgcca gcaaatcagt cgcaacaggg tgaatgctga aacctttagc
    28261 atcacagctt gttaagcagg tgatagctaa aaatgcaaag ctatcgagct gatgaagcac
    28321 tgccaaatca gcctgcaaac caccaccgct gaatatatca ctcccagcaa tcgttaatac
    28381 cttattcttc ataaatgatt tccttcaaat aaagaccatt accagccgct gtcggtccag
    28441 ctagctgccg attcttactc tctaaaacga gcctgatttg ttcaatgggc aaccgaccat
    28501 tgccgatctt aagcaaggtc ccaaccatat ttctaacctg cttataaaga aagccattcc
    28561 ctgaaaacgt aaaaacaaga aaaccagttt tagggtcctg agtgagggta gctgctgtaa
    28621 tggtacgaac cttattttta acagaggttc ccgcagctgt aaagcctgta aaatcatgcg
    28681 tcccaaccaa atccttaatc gcagcctgca ttttcgcaat atctaaggga taagggtaat
    28741 gggtcgcata atggcgcatc ataggatttt taggacgacc aatatccact aagaattcat
    28801 aggttttgaa atgcttatgg tagcgagcgt gaaaatcatc tgctgcaatc tccagactga
    28861 tcacatcaat atcatctggt gtctgggtat caagtgcaaa gcgaagcttt tcagggtctc
    28921 ttttttgctc caaatcaaag tgaatcactt gaccataagc atgcacacct gcatctgttc
    28981 taccagctcc atgaatctgt atcccttgac cacctgtcaa tttttgcagg gtcttttcaa
    29041 tctcttcttg taccgtacgt gcctgacttt gtctctgaaa accagaaaat aaggtcccat
    29101 cgtaggaaat aattgcttta tatcttgtca tgctattatt ctaccatttc ttccagccat
    29161 cagaaaagag catttacggc ttttgtcccc atacagtttt cgattagctt tgataatcaa
    29221 gcttgatttg acgccaacag gcaaaaaaag gctactgaca aggactagct tttctgctat
    29281 aatttctcta atattcaata agtagactgg agagcaaatg aaggtaacaa aatttggcgg
    29341 cagctcctta gcatctgccc agcagttaga aaaggtcttg gctattatca aggacgatcc
    29401 tgagcgtaaa atcatcgttg tctccgcacc aggcaaacga tcccctacag acacaaaggt
    29461 gactgatgca ctcattgctt attacaaagc ctacgtctca gaccgtcatt atcacaagca
    29521 tttggaatgg attatcaatc gttaccaaca aatctgtaat gacctaactc tagatagcaa
    29581 aatcatcacc caaattaaag cttccttaga gcaattggca cggcttccaa aagaacataa
    29641 tccctattta tacgatacct ttcttgcggc cggtgaggac aataatgcta agctagtagc
    29701 tgcctacctc aaggcaaatg gcttaactgc aagctatctc caccccaaag atgcaggtct
    29761 aatcgtaagc agtgagccac agcatgcacg tcttcttcca atcagttacg ataagctaga
    29821 ggccttaaag gatcatgatg acattcttgt tattcctgga ttctttggtg tgacaaatga
    29881 aaaccagatt tgtaccttct cacgtggtgg ctctgatatt accggctcca ttattgcagc
    29941 aggagtcaca gctgacagct atgaaaattt tacagatgtc aatggcatct ttgctgccca
    30001 ccctggtgtt gttaagcagc cacagacgat cactgaatta acctacagag aaatgcgcga
    30061 gttagcctat gctggctttt ctgtcctcca tgatgaagca ttaatccctg cttaccgagg
    30121 gaaaatccca atcgtcatca aaaacactaa caatcccagc cacccaggta caacaattgt
    30181 tcttgagcac cagaggaaat ccaatcccgt tgtcggtata tcaggtgatg atcactttgt
    30241 cagcattaac ctatctaaat acctcatgaa cagagaaatt ggatttgggc gcaagctcct
    30301 tcagatatta gaggacctca atatcagatg ggagcacatg cctacaggta ttgatgacct
    30361 atcaattgta cttagagaaa gagaattgac ccccatcaaa gaagaagaaa tccttcgcag
    30421 acttgtccag caattagagg ttgatgaggt gtccatcacc aggaaccttt ctattatcat
    30481 gatagtcggt gaaaacatga aaagtcatat tggtgtcaca tctgccgcaa caaaggctct
    30541 atctgaacat catatcaata ttgctatgat ttcccaaggc tcaagtgagg tatctgtcat
    30601 gtttgtcatc aatagcaccg atgaaaaaaa ggccattaga gccttatatc aaaccttttt
    30661 tagccctgat cgacccctgt aaagctccat ataacatctc ttgttaacac caagcttcaa
    30721 aaacagctca caagctagac agtactccta gcctatgagc tgttttgatg atctaaaact
    30781 atcaagatta agcatcggta gtaacgactt aatatgctca cagctatcat aaactctagc
    30841 tttaccttat tgaggaaaag aaaaccagtt ttcacctcag ctaagattaa caacaagcga
    30901 ttaagcactt gctaaaaaca gatagacttc aaaagtgaga catatgtata atttctacca
    30961 gatctaaata aatatagcag cagagcaccg agtttaataa gccatttctg acatgataaa
    31021 ctcgccaagc tctccacaga tcaagatttg ccttatcaat tgatacaaca gccagcattc
    31081 tcaaagatgc acaagatcca tcacagtcta gccatctccc tgcacagtaa gcctttcaat
    31141 ctcgttccgg taaccccttt tatttctcac cagtaaagtc ctgaaagtaa ggtcctatct
    31201 tgcgaagcaa ggcccgtctc ccctcaaacc gctctcccct gatcaaagcc cgaaactgcg
    31261 acagctcacc ctctgtcaat cgctcctcaa cctccttcac aatcaactga taagccacat
    31321 aatcatctac tcccaaacca cctgctggta tcgcatggcc taccgaccca atctcctcat
    31381 aagccatctt atgaaaccga cgcttctgac tctcctgctg ccgcaacacg tccttcaaat
    31441 aagaggaaaa cttggtctta aaataacgat atagcttctc ctcatcctct atcaattctg
    31501 gataagtgac caataaccga tacaagatca accgcccctc ctgtaaccaa tcatctagct
    31561 cccacagctg aatataataa tgctgtctta gcttcataat aataggcttg atcttatcaa
    31621 acaacctcac taaatcatca gtcattatac tttctccttt tcatgcttag tagccttatt
    31681 ataaggagac aaacaaaaaa acaacaggac agaaatgtcc tgttgccttg ctatgcaccc
    31741 tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg tactctatcc agttgagcta
    31801 agggtgcttt tcttaactat tactatccta ccatactatc ccctaaaaag caaggctcta
    31861 taccatctgg aataggtaag tccactgtgg aaatcataga gctttttgag tacacaaaaa
    31921 agagagcacc aaactgatcc tctctaaatg tccgttgtta gtcaacccac tatagttgac
    31981 atagagccaa actccgccag taggactcga acctacgaca tcatgattaa cagtcatgcg
    32041 ctactaccaa ctgagctatg g
//
LOCUS       DARYXS010000013        29501 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.013, whole genome shotgun sequence.
ACCESSION   DARYXS010000013 DARYXS010000000
VERSION     DARYXS010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29501
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.013"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            74..1345
                     /locus_tag="TV193_000477"
     CDS             74..1345
                     /locus_tag="TV193_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEL1512708.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAF
                     FAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
                     VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTL
                     RLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRS
                     GKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLGELQRHGVV
                     SSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVI
                     GGRSRLDVRYIAALYAFNMVRKTLLKSENLL"
     gene            1439..2575
                     /gene="recA"
                     /locus_tag="TV193_000478"
     CDS             1439..2575
                     /gene="recA"
                     /locus_tag="TV193_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEL1512709.1"
                     /translation="MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED"
     gene            2951..3349
                     /gene="spx"
                     /locus_tag="TV193_000479"
     CDS             2951..3349
                     /gene="spx"
                     /locus_tag="TV193_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEL1512710.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLPYKEQNLGKEPLSREEILA
                     ILSKTENGVESIVSSKNRYAKALNCDIDELSVNEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENAEARLRAAL"
     gene            3462..3731
                     /locus_tag="TV193_000480"
     CDS             3462..3731
                     /locus_tag="TV193_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEL1512711.1"
                     /translation="MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR"
     gene            3728..4147
                     /gene="ruvX"
                     /locus_tag="TV193_000481"
     CDS             3728..4147
                     /gene="ruvX"
                     /locus_tag="TV193_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEL1512712.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIRINEDKQDFGFDR
                     LAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDKIEELFHIPVSYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY"
     gene            4157..4456
                     /locus_tag="TV193_000482"
     CDS             4157..4456
                     /locus_tag="TV193_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEL1512713.1"
                     /translation="MTHNHDHEHEVITLVDEQGNEALFEILLTIDGREEFGKNYVLLV
                     PAGSQEDESGEVEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEE"
     gene            5004..6563
                     /locus_tag="TV193_000483"
     CDS             5004..6563
                     /locus_tag="TV193_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEL1512714.1"
                     /translation="MSQLHQEVMLEKVNYLVKDHPSSHTTKYDMKVPSLYKFYIFFFS
                     IIASLLTVAVPFFADTANSVQSQNLYIGMMLTKGQIPYSDLFTTGGFLFFVLIALSYH
                     LGTTVWLVLVQALCFYLTGVYFYKLIHYVTGIQKVALGFTAIYYLLSISLGFGGLYAI
                     QLALPFVLVSLWFLTKYFAGLVKDEAFILFGFAAAIAMLIEPRTLLFWLLACIAIIAY
                     NVSQKHFARGFYQLLAAIFGMLLVFYTAGYFILNLQILSPYLEQALVYPFSYFVTGDL
                     SLILGLTVQLGLVLGLGLLTGLLTFMKQPKLESDLAMKWLLVFVVFSYAGIAAISHDF
                     HTYHLLPLLPYALILLSSSVGRQYEAGLRMVSHRRRKGKNGARRVIAIYLNKHFYVPA
                     IIMLGAVFGTAYQYVTSSAINQERSQIAHYLRQRLTEDQPIYVWDDTSKIYLETQAKS
                     ASQFASPFVNLKKESHQQMLEDELLQNKAVYIVVNKQKALPKAVKKIVTANYKIDRKI
                     DVKGFSLYQKK"
     gene            6660..8858
                     /gene="nrdD"
                     /locus_tag="TV193_000484"
     CDS             6660..8858
                     /gene="nrdD"
                     /locus_tag="TV193_000484"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEL1512715.1"
                     /translation="MITLEKDKVIVQPAIKVIKRDGRLVNFDATKIYSALLKASMKVT
                     RMSPLVEAKLEAISERVIAEIIERFPTNIKIYEIQNIVEHELLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLIHKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKL
                     LPAHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAEKWVIEELRESYAF
                     EKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIELTG
                     SFKSPMGCRSFLQGWKDEQGQDVTSGRMNLGVVTMNLPRIAMESNGDMDKFWELFNER
                     LHICKDALVYRVERVKEATPANAPILYQYGAFGKRLAKTGNVDELFNNRRATVSLGYI
                     GLYEVATVFYGGQWEHNQEAKDFTITIVKEMKKACETWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTDKFGVVADITDKEYYTNSFHYDVRKNPTPFEKLDFEKAYPAAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYECHFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGI"
     gene            8964..9110
                     /locus_tag="TV193_000485"
     CDS             8964..9110
                     /locus_tag="TV193_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512716.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSVAKTDKKSRVQQLRAQFLEKAK
                     QSKK"
     gene            9138..10073
                     /locus_tag="TV193_000486"
     CDS             9138..10073
                     /locus_tag="TV193_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1512717.1"
                     /translation="MLDIGIVGLGAISQKAYLPYMRQLRGINWHLSTRNALVRQEVGQ
                     LFGCARLYSTVNELLEAKLDGVFIHAATKAHLELASLFLQKGIPVYMDKPLTEDFFST
                     QALYQLADKHNTFLMADFNRRFAPGVKKLSTLSTKRKVVVEKNDINRPGDKQFKLFDF
                     FIHPLDTALFLVDRRLVAGYFHYQLTDNDLLSQVSVTLRTEQTIISAAMNLQSGSRRE
                     VMEVQTPKETYHLENLETLRAYRGVDQEIKGFSAWDTTLSKRGFEAIVDSFLQAVKDG
                     VNPVKPETSLLSHWICHQICQSHEADGILDVSLPL"
     gene            10086..10580
                     /locus_tag="TV193_000487"
     CDS             10086..10580
                     /locus_tag="TV193_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1512718.1"
                     /translation="MKLRRPKKQDEASVLEMMAEFEDYQSPHDGGFWNAEHFDYEKWL
                     ESNALMEAGLAIPENWVPAIQLVAFADQQAIGFVNVRLRLNEQLLVKGGHIGYSVRPS
                     QRGKGYAKLMLKEALQLARQKGIREVLVTCHCSNSASRSVILANGGQLKDCNKGIERY
                     WIKA"
     gene            10590..11204
                     /gene="nrdG"
                     /locus_tag="TV193_000488"
     CDS             10590..11204
                     /gene="nrdG"
                     /locus_tag="TV193_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEL1512719.1"
                     /translation="MKENCWNSPKPKEWTSEALSQGRVIDYKAFNFVDGEGVRNSLYV
                     SGCMFHCKGCYNAATWSFKAGIPYTKELEEQIMTDLAKPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRKELPEKDIWSWTGYTWEEMMEETQDKLELLSMIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVKKSLAAGEVVIWDKLNDGDQSFEQMSRDDLI"
     gene            complement(11662..12393)
                     /gene="yaaA"
                     /locus_tag="TV193_000489"
     CDS             complement(11662..12393)
                     /gene="yaaA"
                     /locus_tag="TV193_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEL1512720.1"
                     /translation="MLTFLIPTAKEMKPVPPCYPHQLPQKSLPILEAMAELSLEELAR
                     AYSIRIEAASKEAKRLKAIAQGQSSAYPAYQLFNGLMYRHLKRDNLSKDQQDYLSKQV
                     YITSSFYGIIPTDEKIAEHRHDFHTKVTINGQSLKHYWRPIYDQFAKDHKQIISLLSN
                     EFRDVFSKEYQKLWISPKFMEERSGQLKTHSTISKKARGAFLTACLENNVQTKEALKQ
                     LSFAGFCYNEELSTETNYYYIKKES"
     gene            12853..13056
                     /locus_tag="TV193_000490"
     CDS             12853..13056
                     /locus_tag="TV193_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1512721.1"
                     /translation="MENRIQELRKSRGISQADLADMMCVTRQTIISLEKGRYNASLEL
                     AYKLATFFNLTIEDVFLFEEKGE"
     gene            13058..13511
                     /locus_tag="TV193_000491"
                     /pseudo
     CDS             13058..13511
                     /locus_tag="TV193_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516426.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            13521..14195
                     /locus_tag="TV193_000492"
     CDS             13521..14195
                     /locus_tag="TV193_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1512722.1"
                     /translation="METKHSAVKVIISKLKWFGLALLVFMLEQAPTFLITKEQPMWQT
                     LLLVVIFLLISGGTYYLAVKLHIVGDQAIPKNDYRALWIGLGVVAVFVVKMIGGILLF
                     LEHGPGANTVNQAALEQAGLSPILMVTLVAIVAPIVEEIAFRGLLYGKLFGAESYLGL
                     IFSSIMFGLIHVPTDFGSWFIYGGMGLVLGFVFHKTKKVEYTILIHFLNNALAVLIML
                     LLPYLQ"
     gene            14225..14662
                     /locus_tag="TV193_000493"
     CDS             14225..14662
                     /locus_tag="TV193_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512723.1"
                     /translation="MKNDRWIDKKYQRWEKVYKRLGHSLLTIGVLVGTYGIFLIIQGN
                     HQTGFLLFILGPILLIASCLCYYVFTEPTSLREYLINSYDERNRAIRQKAQAYCFCLF
                     AFLFLMLAIFFPNMTIKELFGYNLPLIVFNLYVMIRAWVSKHM"
     gene            complement(14885..15658)
                     /locus_tag="TV193_000494"
     CDS             complement(14885..15658)
                     /locus_tag="TV193_000494"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEL1512724.1"
                     /translation="MKIGFIGVGKMATAIIQGLTHTPHELIISGSSLARSKEIAGQLH
                     LSYAQSHQELIDQVDFIILGIKPQLFETVLSPLQFKQPIMSMAAGISLDRLAQLTSSH
                     LPLLRIMPNMNAQILQSTTALTGNDLVTADLLATAKELTNSFGTTFEIAEKDFDTFTA
                     LAGSSPAYLYLFIEAMAKAGVKNGLPKDKALSIVSQTVLASAKNLLVSTDSPHDLIDK
                     ICSPGGTTIAGLMDLEKTGLTHSVCSAIDTTIKKAKDLS"
     gene            complement(15742..16809)
                     /gene="pepA"
                     /locus_tag="TV193_000495"
     CDS             complement(15742..16809)
                     /gene="pepA"
                     /locus_tag="TV193_000495"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEL1512725.1"
                     /translation="MIDLFSKIKEVTELDGIAGYEHTVRDYLRAKITPLVDRVEVDGL
                     GGIFGIKESKADQAPRILVAAHMDEVGFMVSEIKADGTLRVVEIGGWNPLVVSSQRFT
                     LYTRAGQAIPVISGSVPPHFLRGANGAASLPAVSDIVFDGGFTDKTEAESFGITPGDI
                     IVPQSETILTANKKNIISKAWDNRYGVLMVTELLEALKDQTLHNTLIAGANVQEEVGL
                     RGAHVSATTFDPELFFAVDCSPAGDIYGNPAHIGDGTLLRFYDPGHIMLKNMRDFLLT
                     TAEEAGVAFQYYCGKGGTDAGAAHLKNGGIPSTTIGVCARYIHSHQSLYALDDFVEAQ
                     AFLQAIVKKLDRSTVDLIKKY"
     gene            17154..17501
                     /locus_tag="TV193_000496"
     CDS             17154..17501
                     /locus_tag="TV193_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEL1512726.1"
                     /translation="MAEIVSFCSSLLFPFCDKMKGMNGKKTRIVSGLIGLGLLAGLGL
                     RLKEVYQERERQRVLVELRAFFSALGEIEVLYINSFSSKRDDVTGGLVMTDGKTYTYH
                     YHKGSIDFKEDLT"
     gene            17498..17815
                     /locus_tag="TV193_000497"
     CDS             17498..17815
                     /locus_tag="TV193_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEL1512727.1"
                     /translation="MIIPTSKEELARLIETEPRLVLFFTADWCPDCQYIYPVMPELEA
                     ENPDMTFVRLDRDDFIDLAQDWQIFGIPSFLVMEKGQEKGRLVNRLRKTKAEISDFLA
                     AYH"
     gene            17830..18456
                     /locus_tag="TV193_000498"
     CDS             17830..18456
                     /locus_tag="TV193_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEL1512728.1"
                     /translation="MIFAYNKEQVGDVLMVILEDKKDIKRQVERKGRVARVFAEETGQ
                     TLAWNIFEASALIAVEGNGQVFLSEEELAILNAELAQEGFTERLEASPAPVFVVGQII
                     EMIPHPDSDHLNICQVQIAPDKAVQIVAGAPNAAVGLKTIVALPGAMMPSGSLIFPGK
                     LRGKESFGMMCSPRELALPNAPQKRGIIELGDAAAVGEAFDPAKHWQS"
     gene            complement(18759..19472)
                     /locus_tag="TV193_000499"
     CDS             complement(18759..19472)
                     /locus_tag="TV193_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1512729.1"
                     /translation="MTINLKAYQDMLTRPWGKLMYDLIFAQLGPIAGKTILDFGAGFC
                     ITAEALAVQNEVTAIEPNPDLLFAQKQESIHKIKGSLEALEKLPDQAFDMIICHNVLE
                     YIAPKEHAIYLAQMERLLKPKGQLSLIKHNQVGKVLHSVIFEHDYDKALNVLNGQAFE
                     SLSFAAGQTYSIDDLLRKTDLKLQGYRGLRTCYGLQPNEVKAKPDWLEVLRTIELAIC
                     DQKPYKDMAFFQHVTLSKA"
     gene            19584..19979
                     /locus_tag="TV193_000500"
     CDS             19584..19979
                     /locus_tag="TV193_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1512730.1"
                     /translation="MYNKVILIGRLVAKPELNKTLTDKQVVRFTLAVNRRFKTTTGER
                     EVDFINAVAWGGLAETLASYASKGSLLSLDGELRTRKYDKAGQTHFVTEVLCHSFQLL
                     ESRAQRAIRENNAANDLIDLALEEEKLPF"
     gene            20426..21400
                     /locus_tag="TV193_000501"
     CDS             20426..21400
                     /locus_tag="TV193_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1512731.1"
                     /translation="MRFKQLSLTAFIGLLAMLLTACRQETNQTHQAARVGIIQYAEHS
                     ALDAAREGFIEALEQGGFREGKNLTITTKNAQGDQANLQTMVEQLAGKNDLQLAIATP
                     AAQALLNMDSETPAVFTAVTDPVSAGLVDTLAKPGGNMTGSTDATDVENQIDLLTKAL
                     PQARTVGIFYNSSEVNSEIQAKKAKRELEKKGLKVLMKTVTTTNDVQQVMTSLASQVD
                     AVYLPTDNTVASTATTIGDILKEAKIPSMGSDAAYLSAVLFTSGVDYHAIGMQAGQQA
                     VDILKGKKPASIQVAKPQKASIAVNDDMARLLGIDPEVIKALASNGAN"
     gene            21418..22380
                     /locus_tag="TV193_000502"
     CDS             21418..22380
                     /locus_tag="TV193_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1512732.1"
                     /translation="MKKGSYLILLVLAGFVLVACRSTASPRKVNQSHVNIGILQYMEH
                     DSLTAARRGFEAQLKAAGYTKGDKLSLHYQNAQGDQANLQTISEQLVKQNDLILAIAT
                     PAAQALATVSSDRPIVFTAVTDPISAGLVDRIKKPGGLITGTSDQAPIAKQIDLLAQA
                     LPEAKTIGILYTASERNAEVQVKEAETLLTKVGYRVIKKGIATSNDVQDTAASLMRAV
                     DALFVPTDNTVASTMTMLGELSLANKVPIIGGSTDMVDAGGLLTYGIDYESLGRQAGE
                     MAIKILRGQDPASLAVEYPKTVKLHINQAMADKLAIDTSTLSVD"
     gene            22495..23379
                     /locus_tag="TV193_000503"
     CDS             22495..23379
                     /locus_tag="TV193_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1512733.1"
                     /translation="MSLILSSLSQGLLWSIMAIGVYLTFRILDIADLTAEGSYPLGAA
                     ICAAGIVSGVSPLLATFLAFIGGLLAGLVSGLVHTKLKIPALLTGIITLTGLYSVNLK
                     VLGRANVALLRQRTLVTQLYDLGFTKLAAVLIMGFVFVTIVIFLLALLMKTQLGLALR
                     STGDNNPMSEANGIKTDQMKIMGYMLSNGLIALCGALLCQNNGYADLNAGVGTIVIGL
                     ASIIIAEVMIRQLSIGWRLASIVLGSIVYRLIILAILAIPGMDADLVKLFSAMLLAAV
                     LFVPELQQRLRLRKTSLG"
     gene            23388..24191
                     /locus_tag="TV193_000504"
     CDS             23388..24191
                     /locus_tag="TV193_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1512734.1"
                     /translation="MSAILSIKAIHKTFEAGTINENHVLRGLSLDIEEGDFISVIGGN
                     GAGKSTLMNTLAGTLAFDQGDILLEGKSIKHLSAAKRAKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGKSRGLGWGVKERERQIYRQALQELGLNLENRLKAETQFLSGGQRQAL
                     TLLMASLAKPKVLLLDEHTAALDPKTSTMVMALTKQLVETHGLTTLMITHNLENAIAY
                     GNRLVMLHQGNIVVDIKREEKAKLTVDHLMALFHQNSGHTLLDDALVLG"
     gene            complement(24290..25294)
                     /locus_tag="TV193_000505"
     CDS             complement(24290..25294)
                     /locus_tag="TV193_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512735.1"
                     /translation="MLSRHNIVQRSLVKHLLLLATLLGSLGLGNSLSKADSQDHLHVN
                     LYLIQSDSNLKRYGKRIIDKAIEKVKARPRLKFSSEYEVNQFLNNISRLHPELRLTEQ
                     ETQSNKQQTPSKETRRAEASRNSNTSRPAASLSSYRRYSDAQILANIKAELEKSDYDA
                     IKQFKDDFINRLHSQEIQLNPYRDSSKIPALLFRELQYYLKLHPEMIYHLDGINLSPE
                     VADSFVSRLANAYSLDNMLSILQEARAYGQGIIDTIAKRAEAKAILTEHKNTYKDRNQ
                     RVSEDYYSTAFHEIDEAITIQQLNKAIEIVENEAYRIRNKSFDYNRRHHGFITLRKIS
                     "
     gene            complement(25580..26221)
                     /locus_tag="TV193_000506"
                     /pseudo
     CDS             complement(25580..26221)
                     /locus_tag="TV193_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
     gene            complement(26242..27219)
                     /gene="dusB"
                     /locus_tag="TV193_000507"
     CDS             complement(26242..27219)
                     /gene="dusB"
                     /locus_tag="TV193_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEL1512736.1"
                     /translation="MTRLNSPFRIGHVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEHPMSIQLFGGDAEGLKRAADFIQSHTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIIQEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGTCDHETLARVSRAITRIPFIGNGDVRTVQDAR
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGEVLPELPFAKKLDIAKDHLKRLIR
                     LKGEAIAVREFRGLAPHYLRGTAGAAKIRSAVSRAKTLAEVETIFAQIH"
     gene            complement(27206..28078)
                     /gene="hslO"
                     /locus_tag="TV193_000508"
     CDS             complement(27206..28078)
                     /gene="hslO"
                     /locus_tag="TV193_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEL1512737.1"
                     /translation="MDKLIKTISASGAFRAYVLDCTETVRYAQERHHTLSSSTVALGR
                     TLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATG
                     EVLVGPFMGQGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNV
                     LLDQEDKVKVAGGFMLQVLPGASVEEISHYEKRIQEMPAISTLLASENHIDALLAAIY
                     GEEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLTMLNEDKGAEIVCQFCGTKYQ
                     FDQTDLEVLINDKA"
     gene            complement(28328..>29501)
                     /locus_tag="TV193_000509"
     CDS             complement(28328..>29501)
                     /locus_tag="TV193_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEL1512738.1"
                     /translation="HNLSQLPVLVLSQNLELLQAYDDEERRFPYYELIKTLDIPSNTE
                     LTCYEGTLEESSLMFPIGDKFIFIGPFYTSFFQDSYKEELADSFLKRYPDKSKKELVG
                     YISTIPHFPASHIRSLLIAVDAFFDTNFEMSCQQSINDLLEEAQLIWEDPHIIANLEL
                     ENTPSFHVPAVLNYLNHIIDLVKLGNTELLKHEINCIPSSDVVSSSIPALRAEKNLSI
                     IYFIKLLELSFTENTDVAKNYERIKHFMNLTEKATDLLKVLQIRAAAIISLSESLTNK
                     SVSDKQQIYNSILYYVDKHLYSKLKVSDIAKHLYISESHLRAVFKMYSSISLQTYILK
                     EKVQEAKLLLRRGVPAGEVAKLLYFYDTTHFLKTFKKYTDTTPHDYLAHYQQSITK"
BASE COUNT         8424 a         5364 c         6849 g         8864 t
ORIGIN      
        1 tttcaatgct tcatggatga ttcttttttt gttaaaatga gattgaatgt cgaatagata
       61 agtaggtggg aaaatgaaag ctgaactcat tgcggtggga accgagattc tgactggtca
      121 gattgtgaat accaatgctc aatttttatc agaaaaaatg gcggagcttg gtattgatgt
      181 ttattttcaa acagctgtag gagataatga agagcgtttg ctttctgtta ttgatattgc
      241 tagccagcga agtgatttag tgattttatg tggtggtctt ggtccaacag atgatgatct
      301 aacgaagcag accttagcta agtatctggg aaaagctttg gtctttgatg agcaggcagg
      361 tcaaaaatta gatgcttttt ttgcacatcg taagcaggct gctaggacac caaataacca
      421 acgtcaggcg cagctgattg aaggctctat tgctttgcaa aatcaaacag gacttgcagt
      481 aggtgggtta ataactgtag atagggtaac ctatgttgtc ttaccagggc ctccaagtga
      541 gctaaagcct atggtaaaaa atgagctggt gccccttctt tcagctagtc atgccagtct
      601 atattcaaga gtgctgcgtt tttttggcat tggtgaaagt caactggtga ctgctctgga
      661 ggatttgatt aagcatcaaa cagatcctac tattgctcct tatgcaaaga ccggcgaggt
      721 aacactgcga ctatccacaa aggctgacaa ccaagcatta gctgatgaaa ggctgaatcg
      781 actagaggcg cagctcttat ccataagaac tgtagataat caacccttac ggcgtttgct
      841 ttatggctat ggggaggata attccttggc gcgtgagacc tttgagctat tgaagcgaag
      901 tggtaagacg ataacagcag ctgaaagctt aacagcagga ctgtttcaag ctcagttaac
      961 tgattttgcg ggagcttcac aggtgtttaa cggtggcttt atcacctaca gcattgaaga
     1021 aaaagcaaga atgcttggca ttccattggg tgagctacaa aggcatggtg ttgtgagctc
     1081 ttttacagct gagcaaatgg ctgcacaggc acgctgcttg accaattcag atatcggtat
     1141 tggtctaaca ggtgttgctg gtccagaggc actcgaggga cagccagcag gaacagtttt
     1201 cattggcctt gccactaaga ataaggtaga atctcttaaa gttgttatag gaggccgtag
     1261 ccgtttggac gtgcggtata ttgctgccct atatgctttt aatatggttc gtaaaacttt
     1321 attaaaatca gagaatttgc tataattagg atagtgtatt ttaggaaatt agtaactaga
     1381 cagatgtgag gttatgctgt ttattgcttg ctagtcagcc taaatagagg agaaaatatt
     1441 ggcaaaaaaa gttaaaaaaa atgaagaaat caccaaaaaa tttggtgatg aacgtcgtaa
     1501 agcacttgat gatgcgttaa agaacatcga aaaagatttt ggtaagggtg cggttatgcg
     1561 ccttggtgag cgtgcagagc aaaaggttca ggtgatgagt tcaggcagtc ttgctttaga
     1621 cattgcgctt ggagcaggtg gctatcctaa agggcgtatt attgaaatct atggaccaga
     1681 gtcttctggt aaaacaacag ttgccctgca tgcagtagcg caggctcaaa aagaaggtgg
     1741 tattgcagcc ttcattgatg cggagcatgc cttggaccct gcttatgctg cggcgctggg
     1801 tgttaatatt gatgagctgc ttttgtcaca gccggattct ggtgagcaag gacttgagat
     1861 agcaggtaaa ctgattgatt ctggtgctgt tgatttggtt gttgtcgact ctgttgcagc
     1921 tctagtgcct cgtgctgaga ttgatggtga tattggtgat aaccatgttg gcttgcaggc
     1981 tcgtatgatg agtcaggcga tgcgtaagct ttcagcctca atcaataaaa ccaagacaat
     2041 tgcgatcttt attaaccagc tgcgtgaaaa ggtaggggtt atgtttggta atccagagac
     2101 gacaccaggt ggtcgtgctt tgaaattcta tgcctctgtc cgtctggatg ttcgtggaac
     2161 aacacaaata aaaggaactg gagatcaaaa agacagtagt attggtaagg aaaccaagat
     2221 taaggttgtt aagaataagg ttgctccgcc atttaaggtg gctgaggttg aaatcatgta
     2281 tggagaaggc atctcacgta caggtgagct gattaaaatt gcttcagatt tagacattat
     2341 tcaaaaggct ggtgcttggt tctcttataa cggtgaaaaa attggtcagg gctctgaaaa
     2401 tgccaagaga tatttggctg atcacccaga gctgtttgat gagattgacc ataaggtgcg
     2461 tgttaaattt ggcttgcttg aagatactga ggaaagtgca gctgcagata cagttgcagc
     2521 caaagcagat gagttggttt tagagctaga cgatgccatt gaaattgagg attagtgctt
     2581 agtattagat tttcagataa aggtgctaaa aagggcttaa cagcgatcgt caagcccttt
     2641 ttagcttgtg tttaatcaag ctctgtattg gtctgctcag gagctaggct gtacgcttgg
     2701 ataatttgtt agctgagttt atgttttctt tagggattaa ctgttaagct ataaaagccc
     2761 tagaaaaaag ggacttccta cagacaagat agtggcatag taagcttgct tgcaactagc
     2821 tcaatatagg attttggcct tggttaaagg gatcataaaa gaaaactaaa aaataggtcc
     2881 aaagaccgat attgattaga aaaaaactat gctacaatag aggtatcacg agatagaaag
     2941 tgagaacaac atgataaaaa tttacacgat ttcaagttgt acgagctgta aaaaggctaa
     3001 aacctggctg aatgcccata agctcccata taaagaacag aatttaggaa aagaacctct
     3061 ttcaagagaa gaaattttag ctattttatc aaagactgaa aacggtgtgg agagtattgt
     3121 ctcttctaaa aatcgttatg ccaaagcctt aaattgtgat attgacgagt taagcgtaaa
     3181 tgaggttatt gatttgattc aggataatcc ccgtatttta aaaagtccga ttcttatcga
     3241 tgacaagcgt cttcaggtgg gctacaagga agacgatatt cgtgcctttt tacctcgttc
     3301 tattcgtaat attgaaaatg cagaggcgcg tttacgcgct gccttataaa aagctctgtc
     3361 agagcttttt ttaatatcct aacaaatctg aattcttgtt tattcaataa aaataagcta
     3421 taatagagcg tagcacttaa agttagaaag aaggtgtaag tatgggattt acagatgaaa
     3481 cagtccgctt taatttagac gatggtgata aaaagcagat tagcgaaacg ctgacggcag
     3541 tttatcattc actagatgaa aaaggctaca atccgattaa tcaaattgta ggttatgtac
     3601 taagcgggga cccagcttat gttcctcgtt acaatgatgc tcgcaaccaa attcgtaaat
     3661 atgagcgcga tgagatcgta gaagagcttg ttcgctatta tttgcaagga aatggaatag
     3721 atattagatg agaataatgg gacttgatgt cggttctaag accgtcggtg tggcaattag
     3781 tgatccactt ggttttactg cccaaggact agagattatt aggatcaatg aagataaaca
     3841 ggattttggc tttgatagat tagctgagct tgttaagcaa tatcaggttg atcgatttgt
     3901 cattggcttg ccaaagaata tgaataacac tagtggccca cgtgttgaag caagtaaggc
     3961 ttatggagat aagattgagg agctctttca cattccggtt tcttatcaag atgagcgctt
     4021 gacaactgtt gaggcagagc gtatgttgat tgagcaggca gacatcagtc gtggtaaacg
     4081 taaaaaagta atcgataagc tggctgcgca gctgatttta cagaattatt tagattgtaa
     4141 ctattaagga gaacagatga cacataatca tgatcacgaa cacgaagtca ttacacttgt
     4201 cgatgagcaa ggaaatgaag cattgtttga aattttatta accatcgatg gacgtgaaga
     4261 attcggtaaa aactatgttt tactagttcc tgctggttcg caagaggatg aatcaggaga
     4321 ggttgagatt caggcctatt catttacaga aaatgaagac ggaacagagg gtgatttaca
     4381 gccaattcca gaggattcag acgctgagtg ggatatgatt gaggaagtct ttaatagctt
     4441 cttagacgaa gagtaacaac ctgaggcatt agctttaaaa taataaatag cctagaatct
     4501 tggtgctagc agcatgggtt ttaggctatt tttatggttt atcagacagt aggagtgata
     4561 gctatttcta tgacctctaa atagcctact gttaagagtg tttttagggt cttgtagatg
     4621 ttgcaatagc ctgtaatttc gttgaagtta cttgctgttg tcttttttag tttaagcctt
     4681 aacaaagctt ataggaaatg actcaactta gcacagcata agccgcttat tttgataagt
     4741 aaagaaatag ccaatagcta cttttagctt aaagctgatc attaccagta cccttagctt
     4801 ttctgggtat tatttcgaat aatcttaatg ggggtgattt tatcaaaaga ctcagtcaag
     4861 aagaaaaaag ctttctaaag cattataggc taaagacact gcaccgcttt aaagagctgc
     4921 tgacttatgc cagcatttgt cataaattga ctaaataata gattttgcta tacttgtaat
     4981 atgacatgtc aaggagaaac acattgagtc aattacatca agaagttatg ctggaaaagg
     5041 tcaattattt ggtgaaagac cacccatcgt cacatacgac taagtatgac atgaaggtcc
     5101 ctagtttata taaattttat atctttttct ttagcatcat agcgagcttg cttacggttg
     5161 cggttccttt ttttgcagat actgcaaata gcgttcagtc acaaaattta tacatcggaa
     5221 tgatgttgac taaaggtcag attccatata gtgacttgtt tacaacagga ggctttctgt
     5281 tttttgtgct catagctttg agctatcact tgggaacaac ggtatggttg gtacttgttc
     5341 aagcgctgtg cttttatttg acaggtgttt atttctataa attaatccat tatgtgacag
     5401 gtattcagaa ggtggcttta ggttttacag ctatctatta cctattgtct attagtcttg
     5461 gatttggtgg cttatatgcg atccagcttg ccctgccttt tgtcttggta tcgctttggt
     5521 ttttaaccaa gtattttgct ggcttggtaa aggacgaggc ctttattctc tttggctttg
     5581 cagcggcaat agccatgcta attgagccta ggacgcttct tttttggctg cttgcctgca
     5641 ttgcgattat tgcttataat gtgtctcaaa agcatttcgc tcgaggcttt tatcagctgt
     5701 tagcagctat ttttggaatg cttttggtgt tttatacagc aggctatttt atcctcaatt
     5761 tacagatttt gagtccttat ttggagcagg cgcttgttta tccgtttagt tattttgtga
     5821 caggtgattt atcgctgatt ctcggtttaa cagtccaatt aggacttgtt cttggcttgg
     5881 gactgttaac ggggctgctg acgtttatga agcagcctaa gctagagtct gatcttgcta
     5941 tgaaatggct actagtcttt gttgtgttta gctatgctgg tattgcggct atatcgcatg
     6001 attttcatac ttatcaccta ctgcctttac tgccttatgc tttgatcttg ctatcaagct
     6061 ctgttggccg acaatatgag gcaggactta ggatggttag tcatcgtcgt cgtaagggga
     6121 aaaatggtgc gagacgggtt attgctattt atctaaataa gcatttctac gtgccagcaa
     6181 tcataatgct aggagcggtt tttggcacag cttatcagta tgtgaccagc tctgctatta
     6241 atcaagagcg ttctcagatt gctcactatc taagacagag gctaacggag gaccaaccca
     6301 tctatgtatg ggacgatacg tcaaaaattt acctggaaac gcaggccaag tcagcttcac
     6361 agtttgcctc accctttgtt aatctgaaaa aagagagtca tcaacagatg ttagaggatg
     6421 agctactaca gaataaggca gtctatattg tggtcaacaa gcaaaaagca ttaccaaagg
     6481 cagtcaagaa aatagtgaca gctaattata aaattgacag aaagattgat gttaagggct
     6541 ttagcctata tcagaaaaaa taaataaaat caatatattg tgttggtata aaaaaactta
     6601 acacaatata ttgatttttt tgtgtggcgt gatataatag tcgagtaagg agataggaca
     6661 tgataacatt agaaaaagac aaagttattg ttcagccagc tattaaggtt attaaaagag
     6721 atggacgctt ggttaatttt gatgcaacaa agatctacag tgcgctgtta aaagcaagca
     6781 tgaaggtaac acgcatgtca ccgctcgttg aagcaaagct agaagctatt tctgaacgcg
     6841 ttattgcaga aattatcgag cgatttccta caaatattaa aatttatgaa attcaaaata
     6901 ttgttgagca tgagctatta gccgctaatg aatatgctat tgctaaggaa tacatcaatt
     6961 atagaaccca gcgtgacttt gcccgctcgc aggcgacaga tattaatttt tctattgata
     7021 agctcattca caaggatcag acagtagtca atgagaatgc caataaggat agtgatgttt
     7081 tcaataccca gcgcgatttg acagctggga ttgttggtaa gtctatcggt ttgaagctgc
     7141 tgccagcgca tgttgctaat gcccaccaaa aaggtgatat tcactaccat gatttagatt
     7201 atagtcctta tacgccaatg acaaactgtt gtttgattga ttttaaggga atgctggcaa
     7261 atggctttaa aattgggaac gctgaggttg aaagtcctaa gtctattcaa acagcaacag
     7321 ctcaaatttc acaaatcatt gctaatgtgg cctccagtca gtacggtggc tgtacagccg
     7381 atcgtattga tgagtttttg gcaccatatg ctgagctaaa tttcaaaaag catatggctg
     7441 acgctgaaaa atgggttatt gaggagctgc gggaaagtta cgcctttgaa aaaacaaaaa
     7501 aagacattta tgatgccatg cagtctctag agtatgagat caacacgtta tttacctcaa
     7561 acggtcagac cccctttacc tcattgggat ttggtctagg gacctcttgg tttgagcgtg
     7621 agattcaaaa ggctatttta acgattagaa ttaatggctt aggcagcgag caccgtacgg
     7681 caatcttccc taagctcatc tttacggtca agcgtgggct caatttagag ccagactcac
     7741 caaactatga tattaagacc ttagccttgg aatgtgccac aaagcgcatg tatccagata
     7801 tgttatctta tgataagatt attgagctga caggatcctt taagtcacca atgggctgtc
     7861 gctctttcct tcaaggctgg aaggatgaac aggggcaaga tgttacctca gggcgtatga
     7921 accttggggt tgtaaccatg aatttacctc gtattgctat ggaatcaaat ggcgatatgg
     7981 ataaattctg ggagctgttt aacgaacgat tacacatttg taaggacgct cttgtttatc
     8041 gtgtagagcg cgttaaggag gcaacgccag ccaatgctcc tattctttac caatatggag
     8101 cctttggcaa gcggctagct aagactggca atgttgatga gctctttaac aatcgccgcg
     8161 caactgtatc attgggttac attggcttat atgaggtagc aaccgtattt tacggtgggc
     8221 aatgggagca caaccaagag gccaaagact ttacaatcac tattgttaag gaaatgaaaa
     8281 aggcttgcga gacttggtca gatgaatatg gctatcattt ctctgtttac tcaacaccat
     8341 cagaaagctt gacagatcgt ttttgccgcc tagatactga caaatttggc gttgttgctg
     8401 atattacaga taaagaatac tatactaatt cattccacta tgatgttcgt aaaaatccaa
     8461 caccttttga gaagctagat tttgaaaagg cttatccagc agccggtgct tcaggtggct
     8521 ttatccatta ctgtgagtac cctgttttgc agcaaaatcc caaggccttg gaagctgttt
     8581 gggactatgc ttatgatcgt gtgggctacc taggcacaaa tacgccaatt gataagtgct
     8641 atgaatgcca ttttgaggga gatttcaccc caacagagcg aggctttact tgtccaaatt
     8701 gtggaaacaa tgaccctaag acagtagatg tggttaaaag aacctgtggt tatttaggaa
     8761 accctcaggc tcgtccaatg gtcaatggtc gtcataagga aatctctgct cgtgtcaagc
     8821 acatgaacgg atcaaccatc aagtatccgg ggatataagc cttggagaat aatctcatta
     8881 cacctatatc attgtaaagg attgcttcat gcaagcagtc ctttagttat caagacaggt
     8941 ctgtaacaaa gaaagggaga aacatgggaa aataccagtt agattataag ggaatgcagc
     9001 aagtagagag gtttcatgag aaacattctg ttgcaaaaac agacaaaaag tctcgagtac
     9061 agcagcttag agcacaattt ttagaaaaag caaagcaatc aaagaaataa tggcacactc
     9121 agtaaaggcg gtgaagaatg ctagatattg gaattgttgg gttaggcgct atttcacaaa
     9181 aggcctattt accctatatg cgtcaattaa gaggaatcaa ttggcattta tctactagaa
     9241 atgcgttagt ccgccaggag gtgggtcagc tttttggttg cgcaaggctt tacagcactg
     9301 tcaatgagtt acttgaggct aagttagatg gtgtgtttat ccatgcagcc actaaggctc
     9361 atttagagct ggctagtttg tttttacaaa aaggaattcc agtttacatg gataagcctt
     9421 tgacggagga tttctttagc acgcaggctc tttatcaatt agcagataag cacaatacct
     9481 ttttgatggc agactttaat agacgctttg cacctggtgt caagaagttg tcaaccctgt
     9541 caaccaaacg taaagttgtt gttgagaaaa atgatattaa tagaccaggt gacaaacagt
     9601 ttaagctttt tgacttcttt atacaccctt tagatacagc tttattttta gttgatagga
     9661 ggcttgttgc aggctatttt cattatcagc tgactgataa tgatttgcta agtcaggtta
     9721 gtgtaacctt aaggacagaa cagactatta tttcagcagc tatgaatcta cagtcaggta
     9781 gcaggcgtga ggtgatggag gttcagacac ctaaagagac ctatcaccta gaaaatctag
     9841 agaccttgcg agcttatcga ggggttgatc aagagatcaa gggatttagt gcttgggata
     9901 ctaccttatc taaacgaggc tttgaggcta ttgtggattc ttttttacag gctgtcaagg
     9961 atggtgttaa ccctgtcaag ccagagacaa gtctgttgag tcactggatt tgtcaccaaa
    10021 tttgtcaatc tcatgaagct gatggcatat tagatgtttc tcttccctta taaaggagtg
    10081 ataatatgaa gctacgaaga cctaaaaagc aagatgaagc gtctgtttta gaaatgatgg
    10141 cagagtttga agactatcag tctcctcatg atggtggttt ttggaacgct gagcattttg
    10201 attatgaaaa atggttggaa tctaatgctc tgatggaggc tggcttagct atccctgaga
    10261 attgggtgcc tgccatacag ctcgttgcct ttgctgatca acaggctatt ggatttgtca
    10321 atgtacgctt gagattaaac gaacagctac tggtaaaagg tgggcatatt ggttattctg
    10381 ttagacctag ccagcgtgga aagggctatg caaagctgat gctaaaggaa gccttgcagc
    10441 ttgctcgtca aaagggcatt cgtgaggttt tagtgacttg tcattgcagc aatagtgcta
    10501 gtcggtctgt tattttagct aatggtggtc agctgaagga ttgcaataag ggtattgaac
    10561 gctattggat aaaagcataa gaggcaataa tgaaggaaaa ctgttggaat tctcccaaac
    10621 caaaagaatg gacatcagag gcattaagcc aaggacgcgt tattgattat aaggcattta
    10681 attttgtaga tggggaggga gtgcgaaact cactttatgt ttcaggctgc atgttccatt
    10741 gtaagggctg ctataacgca gcaacctggt cttttaaggc gggtattcct tatacgaaag
    10801 agcttgagga gcaaattatg actgatcttg caaagcccta tgttcaaggt ttgacacttt
    10861 tgggcggtga gccctttttg aatacgggaa tattgattcc tttgattaag cgtatcagaa
    10921 aagagctgcc agaaaaggat atttggtctt ggacaggcta tacctgggag gaaatgatgg
    10981 aagaaaccca ggataagcta gagctgttaa gcatgattga tattttagtt gatggccgct
    11041 ttgatatcac caaaaagaat ctgatgctgc aatttcgtgg atccagtaat cagcgtatca
    11101 tcgatgttaa aaagtcactg gctgctggag aggtggttat ttgggataag ctaaatgatg
    11161 gtgatcagtc ctttgagcaa atgagccgcg atgatttgat ttagtagaga cttatcaaca
    11221 tcactagact tgaaagctaa taatgaaagc atgattttag gctcctgtgg tcttgcttaa
    11281 ccaatctaat aaggggtttt ccccacatta tcctcatact tatccacagg ttgtgaataa
    11341 cctgttggtt tgtggataaa aaagagaatt aaggggttct ttaattctct aggcctgaaa
    11401 aagggttctt tttgatgttt tttcttaaaa gaaagagagg caagtgacct ctcttgaaat
    11461 agtatactta ggctttaagc ctagctttca atatctctga atgtctgatt ttcttaggag
    11521 tcaggcattt tttaatggcg atgggaagta cggcttgtgg gtcgctttgt gtgctaagag
    11581 gctttctgag ctgctatatg tcaatgattg gtgatgtgac agctgaggct tgttcacatt
    11641 ctgaaagcac tgatgttttt cctagctttc ttttttgatg tagtagtaat tagtttcggt
    11701 tgatagctcc tcattatagc aaaagccagc aaagctcagc tgcttaagtg cttccttggt
    11761 ttggacattg ttttctagac aggctgttag aaaggctcct cgagcttttt ttgaaatggt
    11821 tgaatgcgtc ttgagctgtc ctgatctttc ctccataaat ttgggactta tccacagttt
    11881 ttgatattcc tttgaaaaaa catctctaaa ctcgttggat aacagagaaa tgatttgctt
    11941 gtgatcttta gcaaactgat cgtagatagg gcgccaataa tgcttaaggc tttgcccatt
    12001 gatggttact ttagtgtgaa aatcatgccg gtgctctgcg attttctcat cagtagggat
    12061 aatgccataa aaagacgagg taatgtagac ctgctttgag aggtagtctt gctggtcttt
    12121 agagagattg tcgcgcttga gatgacggta catgagccca ttaaagagct gataagcagg
    12181 ataagcagaa ctctgccctt gagctatggc ctttagtctc ttggcttcct tgcttgctgc
    12241 ttctatacgg atgctgtagg cccttgctag ctcctctagg gatagttcag ccatagcctc
    12301 taatatgggc aggctttttt ggggaagctg atgtggatag caaggtggaa ctggtttcat
    12361 ttctttagct gttggaatta aaaaagttaa cataagttta ttgtagtaaa ggcggcaacc
    12421 ttctgtcaag agtgggatac atttggtggt tatgtcatat gaaactaatt tttatatttt
    12481 ttacattttg attagttttt aaaaatatag tgatttagtg ttgcataacc tctctaagta
    12541 tgttaatata tactcaagtc tatttgataa acagaagctc aggtcaagtg agtgttccac
    12601 ttacaataac gcagttgatg atggggagac tcagactcag actcagactc agactcagac
    12661 tcagagtcaa ggaaaagaaa tatagtcttg taggattacc tacagggctt ttttctattt
    12721 tgaattgaga gatcaatata aggtgatgtg ctgtttttta ttaccttaaa catttggata
    12781 ttggctattg acaaaaagtg taaaggaaac tatactatat gtgtaaagtt aacttgacat
    12841 attggaggaa ccatggaaaa tcggatacaa gaactccgta agtcacgagg gattagtcaa
    12901 gctgatttgg cagatatgat gtgtgtcact aggcaaacca ttatctcctt agagaaagga
    12961 cgctataatg cgtcattaga gctggcctat aaattagcga catttttcaa tctgactata
    13021 gaagacgttt tcttgtttga agagaaggga gaatgagatg atatttagtg atttaagcgt
    13081 cctgctgact caaaaaagcc agctagccta tgccaaaagg ctgaagtata tgggcttttt
    13141 cgctctctgt ttaggcggtt tgtttttgtt gctggccttt gacgtgagac tgacgagctt
    13201 tgctcaggga atgctggtag ggcttggtag tggtagctta ttattaggtg ttcgtgcttt
    13261 ttcagattgc ctttaatcct caaaggctga gagcctctta tattaaggct tatgatgagc
    13321 gtcatcaggt agttatcaag ctagctgctg tatcaacctt aatcttatta gtggtgttga
    13381 ttattggctg tttgtgcttg aatgtttttt ggagtttggt ttttggcttt agagtatttt
    13441 tagagatttg tctgtatacg atcttgcttg gttttttagg catcaagcta ttgttagagc
    13501 atatgattta ggaggcttca atggaaacaa aacattcagc agtaaaggtc atcatcagta
    13561 aattaaaatg gtttggctta gctcttcttg tgtttatgct tgagcaggct ccaacatttt
    13621 tgataacaaa agaacagcca atgtggcaga cacttcttct tgtggtcatt tttcttttga
    13681 ttagtggagg tacttattac ctagctgtga agcttcacat tgtgggagat caagctattc
    13741 ctaagaatga ctatcgggca ctttggattg gtttgggagt ggtagctgtc tttgttgtca
    13801 agatgattgg tggtattctg ttgtttttgg agcatggtcc gggagccaat acggtcaatc
    13861 aagctgcctt agaacaggca ggcttatctc cgattcttat ggttacgcta gttgctattg
    13921 tggcaccaat tgtggaagaa attgcttttc gagggctgct ttatgggaag ctctttggtg
    13981 cagagtctta tctgggcttg atttttagca gtatcatgtt tggcttgatt catgtgccaa
    14041 cagattttgg cagttggttt atctatggcg gtatggggct ggtgttaggc tttgttttcc
    14101 ataaaacaaa gaaggtcgaa tacacgatat tgattcattt tttgaataat gcactagctg
    14161 ttcttatcat gcttttgctg ccttatcttc agtagtactg cttgagtaat gaagggggta
    14221 atgaatgaaa aatgatcgtt ggattgacaa aaaatatcaa cgttgggaga aagtgtataa
    14281 gagacttggt cattctttac tgacaatcgg tgtgttggta gggacttatg ggattttttt
    14341 gattattcaa gggaatcatc aaacgggctt tctccttttt atcctggggc ctatactatt
    14401 gattgcgtca tgtctttgct attatgtgtt tacagagcca acgtctttac gagaatatct
    14461 gattaatagc tatgatgagc gtaaccgagc tattcgtcag aaagcacagg cctactgctt
    14521 ttgtctattt gcttttctct ttttgatgct tgcgatattc tttccaaata tgacgatcaa
    14581 ggagcttttt gggtataatc ttccgttgat tgttttcaat ctgtatgtca tgattagagc
    14641 ctgggttagt aaacacatgt aggtcatgtt aacacaaagg agtctagagc aagggctttg
    14701 aatgaaacta tttttctaaa aacgcaaaaa atcgcgtgca gtaacagatt aggccatgtt
    14761 actgcatgcg attttgttgt ttcaaacgtg agctcagaat gacatatcct ttttagaaag
    14821 aataggtatt tagggctgtc ttgagctagt cttaggtaat gagcttggag ctcattggtg
    14881 atggttagga taggtcttta gcttttttga tcgttgtgtc aatggcagag cagacagaat
    14941 gtgtcaggcc tgttttttca agatccatca agcctgcaat ggttgtgccg ccgggactgc
    15001 agatcttatc aatcaaatca tggggactat ctgtgctgac tagcaggttc ttggcgctag
    15061 ctaggacagt ttgactaacg atactaaggg ccttgtcttt aggcagtcca tttttgactc
    15121 cggcctttgc catagcttcg atgaaaaggt aaagataagc aggacttgac cctgctagag
    15181 cagtaaaggt atcaaaatcc ttttcagcta tttcaaaggt tgttccaaag ctgttggtta
    15241 gctctttagc agtagctaat aaatcagcag ttactaagtc attaccagtc aaagcagtgg
    15301 tgctttggag aatttgagca ttcatatttg gcatgatacg taggagtggc aaatgagagc
    15361 ttgttaattg agctagtctg tctaaggaaa taccagcagc cattgacatg ataggctgtt
    15421 tgaactgtag agggctaaga acagtctcaa agagctgtgg cttgatccct agaatgatga
    15481 agtcaacctg atcgatcagc tcttggtgag attgggcgta gcttaggtgc aattggccag
    15541 caatttcttt agagcgagct aaggatgagc ctgagatgat tagctcgtgt ggtgtgtgtg
    15601 ttaggccttg aatgatagca gttgccattt tgccaacacc gataaatcca attttcataa
    15661 taatgttcct aaaaatgaat aaaggctcaa taggctagag tgctcattga accttagatt
    15721 cgcattttag ccttatcctt cctagtattt cttgattaaa tcaactgttg agcggtcaag
    15781 ctttttgaca atggcttgca aaaaggcctg tgcttctacg aaatcatcta aggcgtacaa
    15841 gctctgatgt gagtgaatgt agcgagcgca gacaccgatt gtggttgaag ggataccgcc
    15901 atttttaagg tgagcagcac cggcgtctgt accgccttta ccacaataat attggaaggc
    15961 aaccccagcc tcctcagcgg tggttaatag gaagtctcgc atgttcttaa gcatgatgtg
    16021 tccgggatcg taaaagcgta gaagggttcc atcaccaata tgggcaggat tgccataaat
    16081 atcaccagca ggtgagcaat caacagcaaa gaaaagctca ggatcaaatg tagtggctga
    16141 cacatgggca ccacgaagcc cgacttcttc ttggacattt gctccagcaa taagggtgtt
    16201 gtgaagtgtc tggtctttta gggcttctag cagctcagtg accatgagaa caccatagcg
    16261 gttgtcccag gcctttgaga tgatattctt tttattggca gttaaaatgg tttcagactg
    16321 cggtacaata atatctcctg gtgtgatgcc aaagctttcg gcttcagttt tgtctgtaaa
    16381 gccaccatca aaaacaatat ctgaaaccgc tggcagacta gcagcaccat ttgccccgcg
    16441 cagaaaatgg ggaggaactg agcctgaaat aacaggaatg gcttggccag cgcgagtgta
    16501 taaggtaaag cgctgtgagc taacaactag tggattccag ccgccaattt caacaacccg
    16561 cagtgttcca tcagctttaa tctcgctcac cataaagcca acctcgtcca tgtgagccgc
    16621 aacaagaatg cgaggagctt gatccgcctt gctttctttt atcccaaata tgccgccaag
    16681 tccatcaacc tccactcggt caacaagcgg cgtgatctta gcgcgtaagt aatcccgaac
    16741 agtgtgctcg tagccggcga tgccgtctaa ttcagtaact tctttaattt ttgaaaataa
    16801 atcaatcatt tgtatactcc atttgtcatg taagattaaa ggtatcacgt ctgcctctat
    16861 tctatcattt tttagtgaag aatgggaaac agcttgagca taggaaaaga gtttgggaga
    16921 ttaggtgtgt ctttcttgct tgataagctg cttattatca gtttgattca gatgagataa
    16981 ctgctggtat tgatggaatg aaacagctat gcacaacagc cttgacaagg atcgacaggc
    17041 ctgagctgtc ttatgctatc aattgcactt aggtagagca gtagcctgat attgatgtga
    17101 ttagttgctc ttgtcaggtg gtttattagt atttcctaaa gtgtcagcta gtcttggctg
    17161 agattgttag cttttgctct agcctattat tccctttttg tgataaaatg aaaggtatga
    17221 atggaaaaaa gacacgtatt gtttcaggat taattggact gggtctgcta gccggcttgg
    17281 gattgaggct taaggaagtc tatcaagaaa gagagcgtca gagagtattg gttgaattgc
    17341 gcgccttttt ctcagcctta ggagagattg aggtcttgta catcaactcc tttagctcaa
    17401 agcgtgatga tgtcactggt ggccttgtca tgacagatgg taagacctat acttaccatt
    17461 accacaaagg aagtattgat tttaaagagg atttgacatg attattccaa catctaagga
    17521 agaacttgct aggctaattg agacagagcc taggctggtt ttgtttttta cagcagattg
    17581 gtgtccggat tgccagtata tctatcctgt aatgcctgag ctagaggctg aaaacccgga
    17641 tatgaccttt gtccgccttg atcgcgatga ttttatcgat ttagcgcagg attggcaaat
    17701 ttttggcatt ccaagctttc ttgttatgga aaaggggcag gagaagggcc gtttggtcaa
    17761 tagattacga aaaacaaagg ctgagattag tgactttcta gcagcctatc actaagagga
    17821 gaaaatgaga tgatttttgc atataataaa gagcaggtcg gtgatgtttt gatggtgata
    17881 ctagaggata aaaaagacat caagcgacag gttgagcgta aggggagagt agcgcgtgtt
    17941 tttgcagaag agacagggca aacccttgct tggaatattt ttgaggcgtc agccttaatc
    18001 gctgttgagg gaaatgggca ggttttcttg tctgaggagg agttagcgat tttaaatgcg
    18061 gagcttgctc aagaagggtt tactgaacga ttagaggcta gcccagcccc tgtttttgtt
    18121 gtggggcaaa tcattgagat gattcctcac ccagatagtg atcatttgaa tatctgtcag
    18181 gtacagattg ctcctgataa ggctgtgcaa atcgttgcag gagcacctaa tgctgctgtt
    18241 gggttaaaaa caattgttgc cttgccaggt gctatgatgc caagtggcag ccttattttt
    18301 ccaggaaagc ttcgtgggaa ggaaagcttt ggtatgatgt gttctccacg cgaattggcc
    18361 ttgccaaatg ctccacaaaa gcgtggtatt attgagcttg gtgatgctgc agcggttggt
    18421 gaagcctttg atcctgctaa gcattggcag agctagcagg acttgatcag cattaaaatg
    18481 gtgtttagtc cttcttttgc ttggtgaaaa gcctttggac cttgagccat gcagtgcttt
    18541 ttgctggtct gtgactgtct ttagcttcag gatcgaagca ttagagtagc tgcttaactt
    18601 attgtcagcg ctgttgattg cagtagcgct atgcttgtga caagtgaagg caaagcctat
    18661 caatgccctt ggctagggct aaaaattgtc tttagagtca cttttgaggt gagtagctcg
    18721 ctaatttcgg tattgaacgg tgcttaggta ccgttttttt aagctttgct gagtgtgaca
    18781 tgctgaaaaa aggccatgtc tttatatggc ttttggtcac agatggctaa ttcaatcgtc
    18841 cgcaacactt ccagccaatc aggcttagct ttaacctcat ttggttgaag tccgtagcat
    18901 gtccgcagtc cacgatagcc ttggagcttc aaatcggtct ttctgagtaa gtcatcaata
    18961 ctgtaggtct gacctgctgc aaaggataaa ctttcaaagg cttgtccatt tagcacatta
    19021 agtgccttgt catagtcgtg ttcaaaaata acagagtgga gaacttttcc gacttgattg
    19081 tgcttgatga gtgatagctg ccctttaggc ttcaatagac gttccatctg agctaggtag
    19141 atcgcatgct cttttggggc gatatattct aagacattgt ggcatatgat catatcaaag
    19201 gcttgatcag gcagtttttc tagcgcttct aatgaacctt ttattttatg aatgctttct
    19261 tgcttttggg caaataatag gtcaggattt ggctcaattg cagttacttc attctggacg
    19321 gctaatgcct ctgctgtgat gcaaaagcct gctccgaaat ctaaaatagt cttgcctgct
    19381 atggggccta attgggcaaa gatcaaatca tacatgagct ttccccaggg ccttgtgagc
    19441 atgtcttgat aggctttaag attaatagtc attatctagt tttcctttct ttagctgctg
    19501 tgagctattg gcaggatttc taaacttcac agcttgtcct tattttacca tgttttacga
    19561 ataataagat aaggaggtat gacatgtaca ataaagtaat cttgataggc cgtttagtgg
    19621 ccaagccaga attaaacaag acattaacgg ataagcaggt cgttcgattt accttagcag
    19681 ttaatcgtcg gtttaagacg acgactggtg agcgtgaggt ggattttatc aatgctgttg
    19741 cttggggagg tttggctgaa accttggctt cctatgctag caaggggagt ctgctgtcac
    19801 ttgatggcga gcttcgcaca cgaaaatatg acaaggcggg tcagactcat tttgtgacag
    19861 aggttttgtg tcattctttt caattgctgg aaagtcgagc gcaacgagct atacgtgaaa
    19921 acaacgctgc taatgatttg attgatttgg ctttagagga ggaaaagctt cccttttaaa
    19981 gacagctgct agcttactgt cgctaaggga gtcagacact agcattgtgt atgctagaga
    20041 tctcaacata atctaaaaaa tgacaacgat tctaaaaaaa atcttgacac gtcttagaaa
    20101 aaggtttaca atgtatgaca attaaaatga aagaaaacag gaggtgctgg tatggtagca
    20161 gttagcacag ctcagacgat gactaagcgt tattacttta gcttctttag atagtgtttg
    20221 tagacatgag cgcatggata caaacacact gaacgttatg tttgtatcta tggggctaag
    20281 ggctatttga gttgtttgtc cacatagatg atatctcttc taagtggaca ccatacagca
    20341 tgtattttgt tatctcatga tacctgtata ggaccattta gattatctag atggtcttat
    20401 ttttatgcaa gaaagaggaa atgacatgag atttaaacag ttatccttaa cagcctttat
    20461 agggcttttg gcaatgctgc taacggcttg tcgacaagaa accaaccaaa cacatcaagc
    20521 tgctagagtt gggattattc aatatgctga gcactcagcc ctagatgctg cgcgtgaggg
    20581 ttttattgag gcgcttgagc agggcggctt tagagagggg aagaacctga ccattacaac
    20641 caaaaatgca cagggtgatc aggctaacct gcaaacaatg gtggagcagc tggcgggtaa
    20701 gaacgatttg cagcttgcga tcgcaacgcc ggcagcgcag gcgcttttaa atatggactc
    20761 agagacacca gctgtattta cagcggtaac agatcctgtc tcagcaggtc tggttgatac
    20821 attagctaag cctggtggga atatgacagg ctctacagat gcgactgatg ttgagaatca
    20881 gattgatttg ttgaccaagg cgctgcctca agctaggaca gttgggattt tctacaattc
    20941 aagcgaggtg aattcggaga tacaggctaa gaaggccaag agggagcttg agaaaaaagg
    21001 cttaaaggtc cttatgaaaa ccgtaaccac tactaatgat gtgcagcagg ttatgacaag
    21061 cttggctagt caggttgacg ctgtttacct gccaacagat aatacggttg cctcaacagc
    21121 tactactatt ggggatattt taaaggaggc caaaattcct tcaatgggaa gcgatgctgc
    21181 ttacctgagt gctgttttgt tcacctcagg tgttgattac catgctattg gcatgcaggc
    21241 tggtcagcag gcggtagata ttttaaaggg taaaaaacca gcaagcattc aggttgctaa
    21301 gcctcaaaag gcaagcattg ctgttaatga tgatatggca agacttctgg gcattgaccc
    21361 cgaggtgatc aaggctcttg caagtaacgg agccaactag cgttttagga ggaaggtatg
    21421 aaaaaaggaa gctatttaat actgttagtg cttgcaggct tcgttttggt ggcttgtcgt
    21481 tcgacagcta gtcctcgtaa ggttaaccaa tctcatgtta acatcggtat tttacaatac
    21541 atggaacatg attcgctgac ggcagctcgt cgaggctttg aagcgcaatt aaaggcagcg
    21601 ggctatacta agggagacaa gctgagcctt cattatcaaa atgcacaggg cgaccaagct
    21661 aatttacaga cgatttcaga gcagctagtg aagcaaaatg atttgatctt ggcgattgcg
    21721 acaccggcag cgcaagcctt agcgaccgtc tcatcagata gaccaattgt ttttacagca
    21781 gtaacagatc ctatctcagc aggcttagtg gataggatca aaaagcctgg tggcttgata
    21841 acaggaacaa gtgaccaggc gccgattgca aagcaaattg acttgttagc ccaagccttg
    21901 ccagaggcca aaactattgg cattttatac acagctagtg aacgtaatgc tgaggtgcag
    21961 gtaaaggaag ctgaaacgct actgaccaag gttggttata gggttattaa aaagggaatt
    22021 gccacttcaa atgatgtgca agatactgct gcaagcttga tgagagcagt agacgcgctt
    22081 tttgtaccga cagataatac cgttgcttca accatgacaa tgctgggtga gctgtcattg
    22141 gctaataagg ttccaattat tggtggctca acggatatgg ttgatgcagg tgggctcttg
    22201 acctatggta tcgactacga gagccttggt agacaggctg gagaaatggc cattaagatt
    22261 ttaagaggac aggatccagc aagcctagca gtggagtacc caaaaacagt caagctacat
    22321 atcaatcaag caatggcaga caagctagcg attgatactt ccacattatc agttgactaa
    22381 attgctaggt taaaggctaa atgactgatc tctagccagc tggctaaatg acaaagtctt
    22441 aaccagttag cttagcttac tattaacgat tcatatgaca aaaaaggaga aatcatgtca
    22501 ctcattttat cgagcttatc acagggctta ttgtggtcta ttatggcaat tggtgtttac
    22561 ctgacatttc gtattttaga tattgccgat ttaactgcag aaggttccta tccgcttggg
    22621 gcagctattt gtgcagcggg tattgtatca ggtgtttctc ccttgctggc tacgttttta
    22681 gcttttattg gaggcttgct ggcaggcctt gtctcaggat tagttcacac caaattaaaa
    22741 ataccagcct tactaacagg aattatcact ctgacaggct tgtattctgt gaatctaaag
    22801 gtgctaggaa gagccaatgt ggctttatta cgtcaaagaa ctttagttac ccagctctat
    22861 gatctaggct ttaccaagct tgcagcggtg ctaattatgg gctttgtctt tgtgaccatt
    22921 gtgatttttt tattagccct gctgatgaaa actcagcttg gcctagctct gcgatcgacc
    22981 ggagacaata atccaatgag tgaagccaat ggtatcaaaa cagatcagat gaaaatcatg
    23041 gggtatatgc tatctaacgg tttgattgcc ctatgtggtg ccttgctttg tcagaataat
    23101 ggctatgcag atttaaatgc tggtgttggg acaattgtta ttgggctggc ttcgattatc
    23161 attgctgagg tgatgattag gcagctaagc attggctggc gcttagcttc cattgtttta
    23221 ggctctattg tttatcgctt aattattcta gctatcctag ccattcccgg tatggatgca
    23281 gatttggtta agcttttttc agccatgcta ttggcagctg ttctttttgt gccagaatta
    23341 cagcaaaggc ttcgccttcg aaaaacaagt ttaggatagg agaaatcatg tcagcaatat
    23401 tatcaattaa ggctattcac aaaacatttg aagcaggtac gattaacgaa aatcatgtct
    23461 tgagaggctt atctttggac attgaggagg gggattttat ctcggttatc ggtgggaatg
    23521 gcgctggaaa atccacatta atgaatactc tagcaggcac tctggctttt gatcagggcg
    23581 atattctttt agagggaaaa tcaatcaagc atttatcagc cgctaagcgt gccaaggaca
    23641 tcagtcgagt gtttcaagac cctaagatgg gaaccgcttc acgcttgacc attgaggaaa
    23701 atatggctat tgcttaccgc cgagggaaat caagggggct aggctggggc gttaaagaaa
    23761 gagagcgcca gatctatcgt caggccttgc aggaattagg cctaaatctg gaaaaccgtc
    23821 ttaaggccga gacacagttt ttatcaggag ggcaaagaca agccttgacc ctgttaatgg
    23881 cttccttagc aaagcctaag gtcttgttgc tagatgagca taccgcagct cttgatccta
    23941 agaccagtac aatggtaatg gctttgacaa agcagcttgt tgagacacat ggcttgacaa
    24001 ccctgatgat tacccataat ttggaaaatg ctattgctta tggtaatcgt ctggtcatgc
    24061 tccatcaagg taatattgtg gtggatatta agagagaaga gaaggccaag ctgacggttg
    24121 accacttgat ggcactcttt caccaaaata gtggtcatac gctccttgat gatgcacttg
    24181 ttttgggata ggctaggtga gggttagctc tgttttcaaa tagcagccat aatgaaaagg
    24241 cttaaagcca acgcttctag aaacgctagc tcaagccttg ttataatact taggagattt
    24301 ttctaagagt gataaagcca tgatgacgtc tattgtagtc aaaggatttg tttcggatgc
    24361 gataagcctc attttccaca atttcaattg ccttattcag ctgctgaatg gtaatcgcct
    24421 catcaatctc atgaaaagca gtgctataat aatcctcact aacacgttga ttgcggtctt
    24481 tataggtatt tttatgctct gttaaaatgg ccttagcctc agcacgtttt gcaatggtat
    24541 ctataatacc ttgaccatat gctctagcct cttgaaggat tgacagcata ttgtctagag
    24601 aatatgcgtt tgctaagcgg ctgacaaagc tatcagcgac ctcaggactt aaattaatac
    24661 catctaagtg ataaatcatc tctgggtgta gctttaggta atactgcaat tcgcggaaca
    24721 aaagcgctgg aattttcgac gaatccctat atggattgag ctgaatctcc tgactatgta
    24781 gcctattgat aaaatcgtcc ttgaactgct taatagcatc gtagtctgat ttttctagct
    24841 ctgctttaat attggctaga atctgggcgt ctgaataacg acgatagctt gatagtgaag
    24901 cagcaggcct actagtattg gaatttcgag aagcttctgc tcttctagtc tctttgcttg
    24961 gtgtttgctg cttatttgac tgagtctcct gctcggttag tcgtagctca gggtgtaaac
    25021 gactaatatt gttaagaaat tggttaacct catattctga tgaaaacttt agcctaggtc
    25081 tggccttgac cttctcaata gccttgtcaa taatcctttt cccgtacctt ttgagattac
    25141 tgtcagactg gatcaaataa agattaacat gtaagtgatc ttgactatcc gccttagata
    25201 agctgttacc aaggccaagg cttcctaaga gcgtagctag taacagcagg tgttttacta
    25261 gactacgctg aacaatattg tgacgactaa gcataagtta ttttcccatt ctattgtaat
    25321 ataccagaaa atgttatcaa aataaagata agatgtcaat gtcattaatg gtggttaatc
    25381 tttaattaat ggtcgttaat ctagtatatc agagagctag cttaggctgg cagtggtcat
    25441 tctgtgcgtc ttggtacgaa atgcccaagc agatgcagct cactagaatg atcaatagcc
    25501 tcaacacaaa gccccttaca gcttgacaca agctgtaagg ggctttgttg tattaacaga
    25561 taactcaaat ccttgctttt tataataaat ctaaggtttt tagcttgtca tcaatcatgt
    25621 gcagaacggt tgccaaatcc tctgggtttt gcacgaaatc aagcttgttt ccatcaatct
    25681 tcatcttagg tgaaacgtca tattgctcat accagcttgg gtattcacca tgtacctgat
    25741 ggtaataggc ttctaagtca ggattgtcgt caacctgctc aaaacgtctg ccgcgctttt
    25801 caatgcgctc tagcatcttc tcaaaggaga catcaatata aatcagcaga tcaggccgtt
    25861 tttaaggcat tccttcaagc tcctctagca tattggctaa gagctcttgg taaatttcaa
    25921 gctctgtctt ggtaacattt ccatttttat agttaagtgt caagaagagc tcatcttcaa
    25981 agattgagcg gtcaagaata ttattgtctg cctggtaggc ttctttaata gatttgaagc
    26041 gcttgttcaa aaagaaaatt tgtagtaaaa aggcatattt tttagggtct tggtaataca
    26101 gatcaagaac aggattgtta tcaacagcct cgtaaaatac ctctgttcct aaatgctcac
    26161 ccagtgcagc agcaagggaa ctcttgcctg cgccgattgt tccagctaat acaatcaaca
    26221 tgtttctcct tctatgtagt cttagtgtat ttgtgcaaaa atcgtttcaa cctcagctaa
    26281 ggttttagcg cgtgaaacgg cactgcgaat tttggcagcg cctgctgtcc ctcgcaggta
    26341 atgaggggct aacccacgaa attcacgaac agcaatagct tctcccttga gcctgatgag
    26401 gcgcttgaga tggtctttag caatatctag ctttttagca aagggcagct ctggcaaaac
    26461 ctctcctgtc tcaaagaagt gattaatttg ggtgaagaga taagggttgt tcatagctgc
    26521 acggccaatc atgaccgcat ctacaccaat ctcctcaatc atgaacctag cgtcctgaac
    26581 agttctgaca tctccatttc caataaatgg aatcctggta atagctcttg agacgcgtgc
    26641 aagggtttca tggtcacagg tgccagtata catctgctca cgagtacggc catgcatggc
    26701 aagagctgac acaccagcag cttcagcagc caaggcattc tcaacagcta gtgagctgtc
    26761 tgcccagccg gtacgcattt tgacagtcag tggaatgtct aaaacagagg ttacctcctg
    26821 aatgatatgg taaatcttat caggatcgcg aagccacttg gcacctgctt catttttaac
    26881 caccttgtta acaggacagc ccatattgat gtcaacaatg tcagccttgg tatggctctg
    26941 gataaaatca gccgcacgct ttagtccttc agcgtcaccg ccaaatagtt ggattgacat
    27001 ggggtgctca ttgtcatcaa tatgaagcat atgcagggtt ttttcgttat tatagagaag
    27061 tcccttttca gaaatcattt ccatgacaac aaggcctgca ccaaattcct tggcaatcgt
    27121 gcgaaaggcc gaattggtca caccagccat aggtgcaagc actgtacggt gagggatttc
    27181 cacatgacca atcctaaagg gtgagttaag ccttgtcatt gatcagcacc tccaaatcag
    27241 tttggtcaaa ttggtacttg gtgccacaaa attggcaaac aatttcagcc cccttatcct
    27301 cgtttagcat tgtcaacagg tcagctttag ggaggctcat tagggctgac gcaaagcgct
    27361 ctcttgagca gtcacactga aagctcagct gctcttcagc taatcgcttg taaggctctt
    27421 caccataaat agctgctaac agagcgtcta tatgattttc cgacgctaga agggttgaaa
    27481 tcgcaggcat ttcctgaatg cgcttctcat agtggctaat ctcttcgaca gaagctccag
    27541 gcagcacctg cagcataaag ccgccagcaa ccttgacctt gtcctcttga tctagaagca
    27601 cattaaggcc gacagcagat ggtgtctgct cagactctgt caagtagtag gccagatcct
    27661 caccaatctc accggtaatc aagggtgttg tagaggtgta gggattgcct gttccatagt
    27721 ccgtaattgt cacaaagtgt ccctgtccca taaaaggacc aaccagtact tctccagttg
    27781 ctgttttttt gatatcaaca ccgggatttt gaatatagcc cttgacatgc ccttttgtgt
    27841 cagcaacaga aataatatgc ccaaaggagg aatcgccaat aaccttgaca gtaaccttac
    27901 tatctccttt ttggttggca gctagaatct gattggcaat caaggtacga ccaagtgcaa
    27961 ccgttgaaga tgataaggta tgatgccttt cctgagcata tcgaacagtt tcggtgcaat
    28021 ccaaaacata ggccctgaag gcaccggagg cagaaattgt tttaattagt ttatccataa
    28081 tttctattat agcataatga acaaggcttg tgctggttgc tttagaggaa agctgcttga
    28141 aaatagagaa acactatttg gttaataata gcagctctat aaagccactt aaaaacagag
    28201 cagtgctaac aaatggtagt attcttgtcc ttagcacgca gtaagctaat cacctaagtc
    28261 agtacaatca aacaagcatc aaaaaacagc tccgataggt tgattaaagg aagaaatgat
    28321 aaaagagtta tttcgtaatg ctttgctgat aatgagcaag gtaatcatgt ggtgtcgtat
    28381 cagtgtactt tttgaaggtt ttcaaaaaat gggtggtatc gtagaaataa aggagcttag
    28441 ccacttctcc agctggtact cctcttcgta aaagtagctt ggcttcttgt actttttcct
    28501 tcaaaatata ggtctgcaac gaaatagaag aatacatttt aaaaacagct cgtaaatgtg
    28561 actctgagat ataaagatgc ttagcaatat ctgatacctt taattttgaa taaaggtgct
    28621 tatcgacgta atataaaata ctattataaa tttgctgctt atcagaaaca cttttgttag
    28681 tcaatgattc tgagaggcta ataatagcag ctgctcttat ttgaagcacc ttaaggagat
    28741 ctgtagcttt ttcagttagg ttcataaaat gcttaatgcg ctcgtagttt ttggcaacat
    28801 cagtattttc agtaaagctt agttcaagca gcttaataaa ataaataata gaaagatttt
    28861 tttcagctct taatgcggga atagaagagg agacgacatc tgatgaaggg atacaattga
    28921 tttcgtgctt taatagctct gtattaccca gcttgactaa atcaataata tgattcaaat
    28981 aatttaagac agctggcaca tgaaatgacg gggtattttc caattcgaga ttagctataa
    29041 tatgaggatc ctcccagatt agctgggctt cctccagtaa atcattaatg ctttgctggc
    29101 agctcatttc aaagttggtg tcaaaaaagg catcaacagc tatcaaaagg cttcgaatat
    29161 gagaagcagg aaaatgagga atggtagaga tatagccaac tagctctttt tttgacttat
    29221 caggatagcg cttcaagaag ctatcggcta attcctcctt atagctatcc tgaaagaaag
    29281 aggtgtaaaa aggcccaatg aaaataaact tgtcaccaat aggaaacatt agagaggatt
    29341 cctcaagcgt tccctcataa caagtgagct cagtattact aggaatatct aatgttttaa
    29401 ttaattcata gtaggggaat cgacgctcct cgtcatcata agcctgaagg agctcaagat
    29461 tttgagaaag cactaaaaca ggtaattgtg ataggttatg c
//
LOCUS       DARYXS010000014        29355 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.014, whole genome shotgun sequence.
ACCESSION   DARYXS010000014 DARYXS010000000
VERSION     DARYXS010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29355
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.014"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            33..347
                     /locus_tag="TV193_000510"
     CDS             33..347
                     /locus_tag="TV193_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1512739.1"
                     /translation="MVVLQNNSSTASERATALARGVQALSSAGAVSKDMKTTVTGNRS
                     DASSAIDLSHNVSAQVVGIIASMSQHIQSVSASFQAMDLQLGKELGRLENRRRFSLND
                     PK"
     gene            352..684
                     /locus_tag="TV193_000511"
     CDS             352..684
                     /locus_tag="TV193_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3958 family protein"
                     /protein_id="HEL1512740.1"
                     /translation="MYQKERLDKRLETIAQELKRNEQRFEDYEELSNLAAQLLTAAAT
                     TFRSSSDSHLFEGALAEECYLKRKTQASLEQSHEELLGEQRRLYQEEEALTRQLKLVK
                     GKERANEH"
     gene            686..2284
                     /locus_tag="TV193_000512"
     CDS             686..2284
                     /locus_tag="TV193_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512741.1"
                     /translation="MYLGSSDQQASSVGKVLQQRITAYKSLQRALEQLVSSSPDLSGH
                     TYASAKRYSEQVLIPLMRGCILLDEAIKEACAAFPNDYRRQVDSVDLKESELVDQISR
                     SDRIIGRYVELIDLEYRQELPNYSYITNLKSGASNQRQVKRKLEEKLLKLREFDSNSR
                     HLFSSIAALAEAVNIGIRQTKTSWNGTSQTFTLPRALDLEWTKVVEKRWTQREEKASK
                     LKLQQAAEKLSRETGIKYEDAYRFVMDGVLSDENKNKIKSVKKLVKYTKGGLYIVSSG
                     RYYWKHSGKHYWKNTPNKTWNIWKASKNDPNFDKGGIKGKHFSKKGARYTDLPGIKQL
                     KKSETVQSLISKISKDNQGKLTKVGKGLKKVDKELSNISSKLKSYEHGRLNRDLKMMK
                     ENNLGKSLGKFGKVGKAASKVLKFAGKGLKVAGWVGAAINVKDSVETYKKKGYSNEQT
                     AALTARKVAVDTATTVVGSNIGRVTGAVIGQAVIPIPGVGAAIGSVAGSILGAMAGSW
                     IGSTINDNLDKNVKPKQSGRSLAW"
     gene            2278..2964
                     /locus_tag="TV193_000513"
     CDS             2278..2964
                     /locus_tag="TV193_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512742.1"
                     /translation="MVMLMRTLLFPVDNGLDSGLTGDGYAAEYDLWTGKVTWRQLGDG
                     KIKRQQKVAAIINLIAAAISPLVIMSIIFTAKSLKLFDVDTSTTIYRYAPLMVGLVFF
                     FSFELLMLAIRRLYPLAKEEPSLKRQHGYFKTMYDNTIRENDGVFNNLSVPFIGLYVA
                     FLIAFSVIPIFYSQYLQQNSFWSYLGNLVGSSILISLVPNFLWNVLVKQLIYIKLIRK
                     TKEKILKNET"
     gene            2986..3672
                     /locus_tag="TV193_000514"
     CDS             2986..3672
                     /locus_tag="TV193_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512743.1"
                     /translation="MVMLMRTLLFPIDNGMDNNLIGDGLSAEYDLWTGKVTWRQPSDD
                     KIRTQQKVAFVLNLIAGSLSPLAIFLFVIIVRRLGVFSGDTNSMIFKWAPLIVGFILF
                     ISFELLMLALRSRYTILEKEPDLDRQLYYYRTMYDNTIHDNSGVFNNLSVPYVGLYIT
                     LFLIFLIIPLCYHFYLHPSSFGDYLAALSVTSLLISLFPNFLWNGVLKHVIYVKLIRQ
                     TKERILKNET"
     gene            3694..4371
                     /locus_tag="TV193_000515"
     CDS             3694..4371
                     /locus_tag="TV193_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512744.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGDGYAAEYDLWTGKVTWRQATKQ
                     TIEKQQALTSNLLIIASCLSPVTVAGMILLSRSFPIFEEDLSEKIDTYAPIILGVVLF
                     LAFETLMLAIRGRDPLAEKEPDLKRQHDYFEKMFDFAIRRNLSSDNLKTPYIATYFAF
                     GISLLCIPFSYYVYLNPEQFPNLDYGHLSILLVTSILISLVPNFLWNVLLKHIIYIKL
                     IRKTKGQ"
     gene            4378..4692
                     /locus_tag="TV193_000516"
     CDS             4378..4692
                     /locus_tag="TV193_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1512745.1"
                     /translation="MNKPEHILPIGTIVLTETGEIPLMIVSRASLFDDNGEIGYFDYA
                     AVPYPEGIGNDNEYLFFNHEDIADVIYFGYVNSNEQLFAEAYDDLVKTSGYRKLSLDH
                     HQ"
     gene            5140..5823
                     /gene="rpiA"
                     /locus_tag="TV193_000517"
     CDS             5140..5823
                     /gene="rpiA"
                     /locus_tag="TV193_000517"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEL1512746.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRIKEE
                     GLQVVGVTTSSVTTKQAEGLGIPLTSIDDIDCIDLTVDGADEVDKAFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDESKLVDHLGAFKLPVEVVQYGADRLFRVFERAGYKPSFRMK
                     GDKRLITDMQNFIIDLNLGCIENPCEFGRLLDQTVGVVEHGLFNGMVDKVIVAGQAGV
                     TVLEANQST"
     gene            5901..7112
                     /locus_tag="TV193_000518"
     CDS             5901..7112
                     /locus_tag="TV193_000518"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEL1512747.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEEVIPVEELYRICEYARSITLERPALLGRIIARPYIGEPGSFTRT
                     ANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTA
                     MIGTSFLADLV"
     gene            7325..8134
                     /locus_tag="TV193_000519"
     CDS             7325..8134
                     /locus_tag="TV193_000519"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEL1512748.1"
                     /translation="MTLLEKIRETQAFLESKGIDKPEFGLILGSGLGELANEVEQAIV
                     IDYADIPNWGKSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCHSLLVTNAAGGIGYGPGTLMLINDHINMTGTNPLIGENLDEFGPRFPDMSDAYTA
                     AYRETARSVAEKLGLDLQEGVYLGCSGPTYETPAEIRAFKVMGADAVGMSTVPEVIIA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTERIKENFKGLVKAILAEL"
     gene            8225..9010
                     /locus_tag="TV193_000520"
     CDS             8225..9010
                     /locus_tag="TV193_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEL1512749.1"
                     /translation="MTDMEHTISILLEVYAYSHAYKIARTLPDFSPKVLYLLELLKER
                     RELNVAYAFQHRAENRLIEDRHQVKLLLNEAQEEEQTANYLLDLAAKVKNGEIIDFVR
                     SVSPVLYRLFLRLLEQAVPDVQSYIIDTKNDQYDTWNFKAMEKADNDLFRSYLAQRQP
                     RHVTTRSLADLLVLSELPADIKRLVVVLRQFEKSVRNPLAHLIKPFDEEELYRTTHFS
                     SQAFLDGLIRLAVFSGVNYIKEPFYFDVVNAVIEKELLDSAKP"
     gene            complement(9143..10051)
                     /locus_tag="TV193_000521"
     CDS             complement(9143..10051)
                     /locus_tag="TV193_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1512750.1"
                     /translation="MRIQQLQYIIKIVECGSMNEAAKQLFITQPSLSNAVKELEQEMG
                     ITIFIRNPKGITLTKDGVEFLSYARQIIEQTALLEDRYKNHNTSRELFSVSSQHYAFV
                     VNAFVSLLKRADMTQYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFEE
                     NHLTVSTLFKTTPHIFISKSNPLANKTSLTIDDLLDFPYLSYDQGIHNSFYFSEEMMA
                     HIPHSKSIVVSDRATLFNLMIGLNGYTVASGILNTNLNGDQIVAIPLDVPDVIEIVFI
                     KHEKANLSKMGERFIDYLLEEISFNH"
     gene            10391..10840
                     /locus_tag="TV193_000522"
     CDS             10391..10840
                     /locus_tag="TV193_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512751.1"
                     /translation="MTGQSSHQVLIQKLLVSTHYLTLFRDELKLVERTPSILGSEFPV
                     SLVQTELGDIITLVDTLNKQQRLIESTFWYEESAFKLMNKALDIVDNWIKGIDGLIKL
                     CQSKEVFQAIVGDKRTRVFGVLIDVFSSLKISTMSLKEFAAPAALCH"
     gene            11461..12153
                     /gene="pyrF"
                     /locus_tag="TV193_000523"
     CDS             11461..12153
                     /gene="pyrF"
                     /locus_tag="TV193_000523"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEL1512752.1"
                     /translation="MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEG
                     PDIVRYVKSLGHSVFLDLKLHDIPNTVKSTMAVLSRLGIDMTTVQAAGGVEMLRAARE
                     GLGQGPILIAVTQLTSTSEEQMREDQNIQSTLLASVLHYAKRTAQAKLDGVVCSAHEV
                     KAIKSEVPAGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITQATDPV
                     KAYHQIKAEWNR"
     gene            12213..12848
                     /locus_tag="TV193_000524"
     CDS             12213..12848
                     /locus_tag="TV193_000524"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEL1512753.1"
                     /translation="MTLAAQIATDLLEIKAVYLRPKEPFTWASGITSPIYTDNRITLS
                     YPKTRSLIENGFVETIKAVFPEVEVIAGTATAGIPHGAIVADKMDLPFAYIRSKPKDH
                     GAGNQIEGHVRCGQKMVIIEDLISTGGSVLEAAAAASREGADVLGVVAIFTYELPVAS
                     INFEKAGLSLVTLSNYSDLIKVAKAKGYIDADGLALLKRFKEDQKHWQHES"
     gene            12900..13643
                     /locus_tag="TV193_000525"
     CDS             12900..13643
                     /locus_tag="TV193_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1512754.1"
                     /translation="MTYKDLLEIGETSYYQTDRLTYYKNPVVSERYFDNYLSYRSMPS
                     LADLKKDLAYVAKEQQDYPSHYAFLFFAENEELSTDMRAYLTDHHFSLEKHLIFTNEL
                     AKLHLKERDISPVTIEQLSETSFSAYLAYKYQANLAYGETYANQCKADNEANLLTNGS
                     TIYLAIKEGKIIGDITAWECGDYIEMDDFSVDEAYRGRGIGTALQRKASQGYKKVILI
                     SEEANRAMYEHQGYQEVAYYWTALKTSTR"
     gene            13878..15332
                     /locus_tag="TV193_000526"
     CDS             13878..15332
                     /locus_tag="TV193_000526"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEL1512755.1"
                     /translation="MIFKDATEMAQAVREGRVSPSALVRDTIKKAQALNPELNAITSE
                     RFSEALAEAAARDFSGKPFAGVPIFLKDLGQEQEGQLATAGSVLFKDYRASKTDYVVQ
                     RLEELGFIILGRSNTPEFGFKNISDSRLHGPVNLPQDKSRNAGGSSGGAAALVSSGIT
                     LLAPASDGGGSIRIPASFNGLIGLKPSRGRVPVGPGSYRGWQGASVHFALTRSIRDTS
                     RLLYHLQVYQVESPFPLVPLTKEELFHPLDRPLRIALYDHMIDGTTASIDAQTALTEA
                     CHFLKEMGHEVVRLDKLPLDIPKVMRDYYLMTSVETAAMFADSQEALGRQVTKADMEV
                     MTWAIYQAGKDILASVYSQALQRWDHYSAEMASFHEQYDLLLTFTANTPAPKHGQFQP
                     SKELIDKLAKAECYPSSQRLALVEAMFEQSLFITPYTALANLTGQPALSLPTYETSAG
                     LPMGIQLIAAKGREDLLLGIARQFERAGLLKLPG"
     gene            15452..16318
                     /locus_tag="TV193_000527"
     CDS             15452..16318
                     /locus_tag="TV193_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1512756.1"
                     /translation="MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIKDKGVLKVAT
                     PATYQPTSYYNDANELVGYEVDLMKEIGKRLDLKVKFIETGYDQAFTSVDSGRVDVSL
                     NNFDITAKRQKKYNISTPYKYGVGGMIVRADGSSGISKADLSDWKGKKAAGASGTEYM
                     KVAKKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMKSQNPNLNVKM
                     SDVLYNPTAQGIIMSKKDDTLKKKIDAVIKDMKQDGSLKTISKTYYAGQDLTVPFGKD
                     KKIPVIDASDVD"
     gene            16346..16999
                     /locus_tag="TV193_000528"
     CDS             16346..16999
                     /locus_tag="TV193_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1512757.1"
                     /translation="MLNLRLILESLGFVLSGLPYTLGISFLSFLTGLLLGLLLAFLRR
                     STSHFSHYLVRSYVSIMRGVPMIVVLFVLYFGLPYYGLELSALLCAYLGFSLVSAAYI
                     SEVFRASIDAIDQGQWEAARALGLPYVSIVKHVILPQAFRIAIPPLGNVVIDMVKSSS
                     LAAMITVPDIFQKAKIIGGREWDYMSMYILVAFIYWVIAFLLERCQGFLEKRLRLLS"
     gene            17130..17537
                     /locus_tag="TV193_000529"
     CDS             17130..17537
                     /locus_tag="TV193_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1512758.1"
                     /translation="MADSIVFRKNHMISTQAFARVLEASGIKRPTKDEARLSQMLKHS
                     NYLWTAWEGDKLVGVARALTDYAYVCYISDLAVDQAYQGQGIGKQLLSFISEDLGDAV
                     ALVLLSAPSAMSYYPKLGFEQSDKAFIIPRKPF"
     gene            17549..18202
                     /locus_tag="TV193_000530"
     CDS             17549..18202
                     /locus_tag="TV193_000530"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEL1512759.1"
                     /translation="MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFK
                     ALQVTPLEETRVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRN
                     HHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKDRPVVFILWG
                     AYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLR"
     gene            18434..19708
                     /locus_tag="TV193_000531"
     CDS             18434..19708
                     /locus_tag="TV193_000531"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEL1512760.1"
                     /translation="MLLIKNGRVMDPKSQLDQVADVLIDNGRILRIAPDIEHDEVEQI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDTE
                     TLQAVLASAAKEKINIYTNASVTKRFNGQELTDFKALLAAGAVSFSDDGIPLESSKVL
                     KEALDLAKANKTFIALHEEDPQLNGVLGFNEHIAKDHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVKVVAFAQQLGAKVTAEATPQHFSKTEDLLRLAGANAKMN
                     PPLRTEQDRLAVIEGLKSGVIAIIATDHAPHHRDEKAVADLTKAPSGMTGLETSLSLG
                     LTNLVEPSHLSLMALLEKMTINPASLYSFDAGYLAESGPADLVIFADKEERLVTEAFA
                     SKASNSPFIGETLKGVVKYTIAKGQIVYQADN"
     gene            complement(19762..20409)
                     /gene="plsY"
                     /locus_tag="TV193_000532"
     CDS             complement(19762..20409)
                     /gene="plsY"
                     /locus_tag="TV193_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEL1512761.1"
                     /translation="MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNT
                     FRILGLKAGAATLLIDIFKGTLATLLPVLVGASNISPITIGFFAVLGHTFPIFAGFKG
                     GKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAH
                     FLLPSYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH"
     gene            20542..22491
                     /gene="parE"
                     /locus_tag="TV193_000533"
     CDS             20542..22491
                     /gene="parE"
                     /locus_tag="TV193_000533"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEL1512762.1"
                     /translation="MAKKEISITNYNDDAIQVLEGLEAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGNEIDVTLNKDGSATISDSGRGMPTGQHALGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGRPVTGLE
                     KIATAPKSKSGTRVTFMPDDKIFSTTEFKWNTIAERLKESAFLLKTVKMTLTDLRGDD
                     PVVEEFHYENGVQDFVAYLNEDKETLTPVIYMEGQEQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTSLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGELAGHLIRKAIKARDARE
                     AARRARDESRNGKKNKKDKGLLSGKLTPAQSKNPKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLDDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKSEKVSYAWTDGEL
                     EDLRKEFGKGASLQRYKGLGEMNADQLWETTMDPDTRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVTFTLEENTVF"
     gene            22593..23408
                     /locus_tag="TV193_000534"
     CDS             22593..23408
                     /locus_tag="TV193_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEL1512763.1"
                     /translation="MKLDICQQSYSLQWGGTYYFALTDYPNIKAWELEKLAAFCAYEK
                     WNHRQTDISCQDSKLLEEVHQFLEAHACAYLFRPSCKLVASTFNINGEAVCCPYLSHT
                     CTVAAALSIFKTGRLLSAVRAFGVTAQELARSDRNAAGDPADYFHYVMLGWSNTTSGY
                     RLAMERLLNRMPNEKDLREHFVPGVSFHYSYSDICQMKGYVFDGYHPAKIKDELSLEE
                     LQACIIPKSWQQRFEAIIPKALRSRVHYLDYKGEGLVEWSDRVYQLLRVISDS"
     gene            23883..26342
                     /gene="parC"
                     /locus_tag="TV193_000535"
     CDS             23883..26342
                     /gene="parC"
                     /locus_tag="TV193_000535"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEL1512764.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVIYMIDHPNAKLDKLMELLPGPDFPTGGI
                     IQGAAEIKKAYETGKSRVVVRSRTEIEDLKGGKQQIIVTELPYEVNKAVLVKKIDDVR
                     VNNKVPDIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTELQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYIAHRKSIIIKRSQFDKEKAEKRLHIVEGLIRVLSILDEIIALI
                     RASDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQQEEHDLRELITTLS
                     AIIGDEATMYNVMKRELREVKKKFAGPRLSELQAESQAIEIDSASLILEEETFVSVTQ
                     GGYIKRTSPRSFHASSLEEIGKRDDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELT
                     DLRWKDIGEHLSQAIANFAADELVIYAELIQSFEEGLYISVTQHGLIKRFERKELTPW
                     RTYKSKSIKYAKLKDIDDRIVAIAPIIMEDLLLVTQQGYALRFSSQEIPIQGLKAAGV
                     KGINLKAQDYLVSACPVNADSFFVLTQRGALKRVAIADIPQTSRANRGLPVLRELKTK
                     PHRVFLAGMVKGDTTTGTIDLFTHDSEDTASDQQLEVISKTGQQYQLALNSLSLSDRT
                     SNGSFISESISDQEVAAARLI"
     gene            26440..27465
                     /locus_tag="TV193_000536"
     CDS             26440..27465
                     /locus_tag="TV193_000536"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEL1512765.1"
                     /translation="MMTTAIDWENLGFEYRKLPFRYVSYYKDGKWDAGRLTEDATLHI
                     SESAPALHYGQQAFEGLKAYRTKNGSIQLFRPDRNAARLQATADRLLMPQVSTEQFID
                     AVKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPANEYIFIVFAMPVGNYFKG
                     GLAPTNFIVSEDYDRAAPYGTGAAKVGGNYAGSLLPGKAAKTAGYSDVIYLDPATHTK
                     IEEVGAANFFGITANNEFITPLSPSILPSITKYSLLQLAEERLGMTAIEGDVPINDLD
                     RFVEAGACGTAAVISPIGGIQYQDKLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPE
                     GWIVAID"
     gene            27533..27763
                     /locus_tag="TV193_000537"
     CDS             27533..27763
                     /locus_tag="TV193_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEL1512766.1"
                     /translation="MSKKEKKIELQLCDQQVTVNNTKIDGYQLQIGKRVVGEIAELDG
                     KFAVLKDSTVDAFFKTLEQAVENIIENYNLNH"
     gene            27824..27904
                     /locus_tag="TV193_000538"
     tRNA            27824..27904
                     /locus_tag="TV193_000538"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27858..27860,aa:Tyr,seq:gta)
     gene            27943..28014
                     /locus_tag="TV193_000539"
     tRNA            27943..28014
                     /locus_tag="TV193_000539"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27975..27977,aa:Gln,seq:ttg)
     gene            28142..29344
                     /gene="rpsA"
                     /locus_tag="TV193_000540"
     CDS             28142..29344
                     /gene="rpsA"
                     /locus_tag="TV193_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEL1512767.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDREADINDYVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     IGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVVEEAAKQARDKVFSTLSEGSVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLALDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLTVGQEVTVKVL
                     DVNAADERVSLSIKALEERPAQAEGEKEEKRQSRPRHQKREAKRDYELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT         8498 a         5462 c         6976 g         8419 t
ORIGIN      
        1 tatacaatta ttagagagtt agaaagagtt atatggtagt attacaaaat aatagtagca
       61 cagctagtga gcgagcgaca gctttggcaa gaggagtcca ggccctctct agtgctggtg
      121 cggtgagcaa agatatgaag acgaccgtta ctggaaatcg tagtgatgcc agctctgcca
      181 ttgatttatc gcacaacgtt tcagcgcagg tagttgggat catcgcttct atgtcgcaac
      241 acattcagag tgtctctgcc tcttttcaag cgatggatct tcagcttgga aaagagttag
      301 ggcgtttaga aaacaggcgg aggtttagtc tcaatgaccc aaaatgagct catgtaccag
      361 aaggagagat tggataaacg cttggaaacc atagcccaag agcttaagcg taatgaacag
      421 cgctttgaag actatgagga actatctaac ctagcggcac aactgttaac agcagctgca
      481 accacctttc gttcatcatc agatagtcat ctctttgaag gggctttggc agaagaatgt
      541 tatttgaaaa ggaaaacaca agcgtccttg gaacaaagtc atgaggagct cttaggagag
      601 cagcgtcgtt tgtaccaaga agaggaagcc cttacccgac aattaaagct agtcaaagga
      661 aaggagagag ctaatgagca ttgacatgta tctggggtca tcggaccagc aagctagtag
      721 cgttggtaag gtcttgcagc agcggataac agcttataag tctttgcaaa gagctttgga
      781 gcaattggtg tcttctagtc ctgacttatc agggcatacc tatgcttctg ctaaaaggta
      841 cagcgagcag gtattgatcc ctttgatgag gggctgtatc ctgctagatg aagccatcaa
      901 ggaagcctgt gcagcatttc ctaatgacta ccgtcgtcag gttgatagtg tggatttgaa
      961 ggagagtgag ctggtggatc agatcagccg ctcagaccgc atcataggtc gttacgttga
     1021 gttgattgat ctggagtatc ggcaggagct gccgaattac tcttatatta ctaatctcaa
     1081 gagcggagcg agtaaccagc gtcaagtcaa gagaaaatta gaagagaagc tccttaagct
     1141 gcgagagttt gatagcaatt cccgtcacct cttttcgtct atcgcagcct tagccgaggc
     1201 agtcaatata ggtatcagac aaaccaagac ctcttggaat gggacaagtc agacgttcac
     1261 tcttcccagg gctcttgact tagagtggac caaggtagta gaaaagaggt ggacgcaaag
     1321 ggaggaaaaa gcctcgaagc tgaagctaca gcaggcagca gaaaaacttt cgagagaaac
     1381 cgggattaag tacgaagatg cctatcgttt tgtgatggac ggtgttctgt cagatgaaaa
     1441 taagaacaaa atcaagagtg taaagaaact agttaagtat acaaagggtg ggctgtatat
     1501 cgtttcctca ggaaggtatt attggaaaca ttcaggtaaa cattattgga aaaatacacc
     1561 aaacaaaaca tggaatattt ggaaagcatc taaaaacgat cccaattttg acaaaggagg
     1621 gatcaaaggt aaacattttt ctaaaaaagg agcccgttac acagacttac ctggtatcaa
     1681 gcaattgaag aagagtgaaa cagtacaatc cctcatttca aaaatttcaa aagataatca
     1741 agggaagctc accaaagttg gtaaagggtt aaagaaagtt gataaagagc taagcaacat
     1801 atcgtcaaaa ctcaagtcat atgagcatgg acgcctaaat agagacttga aaatgatgaa
     1861 ggagaataac ctgggtaaaa gtctcggtaa gtttgggaaa gttggaaaag ctgcaagcaa
     1921 ggtgctcaag tttgcaggaa aaggtctcaa agttgcgggt tgggtaggtg ctgctataaa
     1981 tgttaaggac tcggttgaaa cttacaagaa aaaaggctat agcaatgagc aaactgctgc
     2041 tttaacagcc cgtaaggtag ctgttgatac tgcaacaact gttgtcggaa gcaatattgg
     2101 gcgtgtaaca ggtgcagtta ttggtcaagc agttatacct attccaggtg taggtgctgc
     2161 tatcggttct gttgcaggaa gtattttagg agctatggca ggtagttgga ttggtagtac
     2221 aattaatgac aatttagata agaacgtaaa acctaaacaa tcaggaagga gtttagcatg
     2281 gtaatgttaa tgagaacact gttatttcca gttgataacg gacttgattc aggattgact
     2341 ggtgatggtt atgcagctga gtatgatttg tggactggaa aggtcacgtg gcgacaactt
     2401 ggtgatggaa aaataaaaag gcaacaaaag gtagcagcta taattaatct cattgcagct
     2461 gcaatatctc cacttgtcat catgtctatc atttttacgg caaaaagtct gaagcttttt
     2521 gatgtagata ctagtacaac aatttatcga tatgctcctc tgatggtagg cttggtcttt
     2581 ttcttctcgt ttgaattatt gatgctggct attagacgtc tgtatccatt agccaaagag
     2641 gagccaagtt taaagcgtca acatgggtat tttaagacca tgtatgacaa tactatacgt
     2701 gagaatgatg gtgtttttaa taatttatca gtacctttta tagggcttta tgtagctttc
     2761 ttgattgcct tttcggttat tccaattttt tactctcaat atctgcagca aaattctttt
     2821 tggtcctatt taggaaattt agtaggaagt agcattctta tttccttagt ccccaatttt
     2881 ttatggaatg tcttagtgaa acaattgatt tacatcaagc ttattcgcaa aacgaaagaa
     2941 aaaatcttaa agaatgaaac ctaaacaatc aggaaggagt ttagcatggt aatgttaatg
     3001 agaaccttgt tatttcccat agataatggt atggataata acttaattgg agacggctta
     3061 tcagctgagt atgacctatg gactggaaaa gttacgtggc gtcagcccag tgatgataag
     3121 attagaaccc aacaaaaggt agcatttgta cttaatctta tagctggtag tttatctcca
     3181 ttagctatat ttttatttgt tattattgtt agacgcttag gcgtttttag tggcgatact
     3241 aattcaatga ttttcaagtg ggcaccgcta atagttggat ttatcctttt tatatcgttt
     3301 gaattattga tgttggcgct tagaagtaga tatacgatat tagagaaaga gcccgattta
     3361 gatcgtcaac tatactatta tcgtacaatg tatgataata ctatacatga caattcaggt
     3421 gtttttaaca atttatcagt accttatgta ggtctataca ttactttatt tctaattttt
     3481 ttaatcattc cactttgtta tcatttttac ttgcacccat cttcatttgg ggattatctc
     3541 gctgcattat ctgtaacaag tttgttgatt tccttatttc ccaatttttt atggaatggt
     3601 gtcttgaagc acgttatata tgtcaaactt attcgccaaa caaaagaaag aattttaaag
     3661 aatgaaacct aaacaatcag gaaggagctt agcatggtaa tgttaatgag aacgctgtta
     3721 ttcccagttg ataatggcat gggaacgggc ttgaccggtg atggttatgc ggctgagtat
     3781 gatctatgga ctggaaaggt cacgtggcga caagccacca aacaaacaat tgaaaagcaa
     3841 caagcactaa cgtctaacct tttgattatt gcctcatgct tatcaccagt tactgttgca
     3901 ggaatgatac tgttgagtag aagtttccct attttcgagg aagacttatc agagaaaatt
     3961 gatacttatg ctccaattat tcttggtgtt gtgttatttc ttgcttttga gacgttaatg
     4021 cttgctatca gaggtcgtga tccattagcg gagaaggaac cagatttaaa gcggcagcat
     4081 gactattttg aaaagatgtt tgattttgct attcgtagaa atttgtcgtc agataatcta
     4141 aaaactcctt atatagctac ttattttgct tttggtattt ctttactctg tattccattt
     4201 agctattatg tttatctgaa tccggagcaa ttccctaatt tggattatgg tcatttatca
     4261 atcctgcttg taacaagtat tcttatttcc ctagttccca actttttatg gaatgttcta
     4321 ttaaagcaca ttatctatat caagcttatt cgcaaaacga aaggacaata aaacattatg
     4381 aacaaaccag aacacatttt accgattggt actatagtgc tgacggagac aggagaaatt
     4441 cctttgatga ttgtgagtcg tgcctctctt tttgatgata atggagaaat cggctatttt
     4501 gattatgctg cagttcctta tccagaaggc ataggaaatg ataatgagta ccttttcttc
     4561 aaccatgagg atattgctga tgtcatctat tttgggtatg tcaattccaa tgaacagctt
     4621 tttgcagaag cctacgatga tttggtgaaa acatcaggtt atcgtaaatt aagcttagat
     4681 caccatcaat agaaaaagga catgaagatt atctagaaaa agaaaagaac taatgagcat
     4741 tgacatgtat ctggggtcat cgaaccagca ggctaatgat gtatggccaa tattttgaga
     4801 ggatcggcct gctcctcttt tttgtatgtt caaagctata aaaagcttac tttttgaggt
     4861 ataaagcttc gacaatcaag agtatttgct ctggtggctt taatgatctt gcttatagct
     4921 tctggtcaga ttgttttagc ctgcttgtgc tgtctgatcc agatttgact gaggctttga
     4981 tgacagtcgt gaaggcgggt ttaagaatgg catgtctaat gtcaatttac aatagagaag
     5041 gaaaattgat caaacagtgt gagatattat taacaagttt gcgctttcat ggtataataa
     5101 agtgctagga agcattttat tataagataa gggggaatca tggaagcact gaaaaagatt
     5161 gccggtgtga ctgctgcgca atatgtaaca gatggaatga ccattggatt aggaacagga
     5221 tcaacagctt attactttgt tgaagaaatt ggtcgtcgca tcaaggaaga gggactacag
     5281 gttgttggtg tgacaacctc aagtgtaaca accaagcaag cagagggcct aggtattccc
     5341 ttaacatcaa ttgatgatat tgactgcatt gacctgactg ttgatggtgc tgatgaggtg
     5401 gataaggcct ttaacggtat taagggtggt ggagcagctc tattgatgga gaaaattgtt
     5461 gcaacaccaa ccaaggaata catctgggtt gttgatgaat caaagctggt ggatcattta
     5521 ggtgctttca agctccctgt tgaggtcgtt caatacggtg ctgataggct atttcgagtc
     5581 tttgaaaggg ctggctataa gccctctttt cgcatgaagg gggataagcg tctcataacg
     5641 gatatgcaga actttatcat tgatcttaac cttggctgta tcgaaaatcc ttgtgagttt
     5701 gggcgtctgc tggatcaaac tgttggtgtt gtcgagcatg gccttttcaa tggtatggtt
     5761 gataaggtca ttgttgctgg tcaggctggt gtaacggtcc ttgaagctaa tcagtcaacc
     5821 taattcctag ctcaatcatg ttttacatta ttttataggt tttggggagc caaccgtaac
     5881 ctcccctaga ttggagactt atgtcaaaat ttaatcgtat tcacttagtc gttctagatt
     5941 ctgttggtat tggtgcagca ccagatgccg acaaattctt taatgctggt gtagctgata
     6001 cagattctga caccctcggt catatttcag agacagctgg tctggctgtt ccaaatatgg
     6061 caaaaattgg acttggtcat attcctcgtc ctgtccccct aaagacagtt ccagctgagg
     6121 ctgatcctac tggctatgtc accaaattag aagaggtatc tcttggtaag gataccatga
     6181 caggtcactg ggaaattatg ggcttaaaca ttactgagcc atttgatacc ttctgggatg
     6241 gctttccaga ggagattatc caaaaaatcg aagctttttc aggccgtaag gtcattcgtg
     6301 aagccaataa gccttactca gggacaaagg tgattgatga ttttggtccc cgtcaaatgg
     6361 aaactggtga gctgattgtt tatacctctg ccgaccctgt attgcaaatt gcagcacatg
     6421 aggaggtgat tcctgttgag gagctttacc ggatttgtga gtatgcgcgt tccattaccc
     6481 ttgagcgtcc tgctctttta ggtcgtatta ttgcccgtcc gtatatagga gagccaggca
     6541 gcttcactcg cacagctaat cgtcgtgatt atgcagtctc accgttccaa gacactgtct
     6601 taaataagct ggctgacgct gggatttcta cttatgctgt tgggaaaatc aatgacatct
     6661 ttaatggctc agggattacc aacgatatgg ggcacaataa gtctaacagt catgggattg
     6721 ataccctgat caaaaccttg cagttgccag catttacaaa aggtctttct tttactaact
     6781 tggttgattt tgatgctagc tttggtcacc gtcgtgatcc agagggctat cgtgactgtt
     6841 tgcatgaatt tgatcgtcgc ctgccagaga tcattgccaa catgaaggac gatgatctgc
     6901 tcttgattac agctgatcat ggcaatgacc caacctatgc tggaactgac cacacacgtg
     6961 agtatattcc attgcttgct tactcagcct cctgcactgg agcaggtgtg attccacagg
     7021 gacattttgc tgatatttca gcgactattg ccgaaaactt cggtgtggac actgctatga
     7081 ttggaacatc attcttagct gacttggtat aggagtaagc aaatatcatt tgataggcca
     7141 aggagcttgg cgtatcaaat tgaaaaccag cgctgtggtt aggtctatta ataggcttgt
     7201 ggcaggttgt ctagttctga tgatcggtgt gatattagtt gatttattgg actttgctac
     7261 agcaaaaagc tcaagagaag tatgctttat agtaaaaaat aaataagata aagggagaaa
     7321 taagatgaca ttacttgaaa aaattcgtga aacacaggct ttcctagaaa gcaagggcat
     7381 tgataagcct gaatttggtc tcattttagg ctctggtcta ggtgagcttg ccaatgaggt
     7441 tgagcaggcg attgtgattg attatgctga tattccaaac tggggcaaat caacagttgt
     7501 tggtcatgct ggaaaattag tttatggtga gctggctggt cgtaaagtat tggcacttca
     7561 agggcgcttt catttctatg aaggtaatcc aatggaggtt gtgaccttcc cggtacgtgt
     7621 gatgaaggct ctgggctgcc atagcttgct ggtgacaaat gcagcaggcg gtatcggcta
     7681 tggtcctggg acgcttatgc taatcaatga ccatattaat atgacaggaa caaacccgct
     7741 cattggtgaa aacctagatg aatttggccc acgcttccca gatatgtctg atgcctatac
     7801 agcagcttat cgtgagacag ctcgctcagt agcagaaaaa ctaggcttag acctgcaaga
     7861 gggtgtttac cttggctgtt caggaccaac ctatgaaaca ccagctgaga ttcgtgcctt
     7921 taaggttatg ggagcagatg ctgttggtat gtcaactgtt ccagaggtta ttatcgctgc
     7981 ccactcaggc ttgaaggtgc ttggaatttc agcgattaca aactttgcag cgggcttcca
     8041 atcagagctt aaccatgaag aggttgtaga ggtaactgag cgtatcaagg aaaactttaa
     8101 aggcttggtt aaggctattt tggcagagct ttaaggcttg ctcttagact agcagtaacc
     8161 atgagcgact gctagtactt tgatcgataa gacgaggaaa aataaggatt gggacattag
     8221 agtgatgact gatatggaac atacgataag tattctttta gaagtttatg cttatagtca
     8281 tgcctacaaa attgcaagaa ctctgcctga tttttccccc aaggtacttt atttgcttga
     8341 gcttttaaag gaaagaagag agcttaacgt tgcttatgcc tttcaacata gggcggaaaa
     8401 taggcttatt gaggatagac atcaggttaa gcttttgtta aatgaagctc aagaggagga
     8461 gcagactgca aattacctgc ttgatttggc agctaaggtc aaaaacggtg agattattga
     8521 ttttgtaagg tcagtatcgc ctgtcttgta tcgtctcttt ttgcggctgc ttgagcaggc
     8581 tgtcccagat gttcaaagct atattattga taccaagaat gatcaatatg acacttggaa
     8641 ttttaaggcg atggaaaaag ccgataatga cctctttagg agctatctgg cacaaagaca
     8701 gccacgtcat gtgacgacac gcagcttggc tgatttactt gttttatcag agcttccagc
     8761 tgatattaaa agactagtgg tagtcttaag gcagtttgaa aaatcagtcc gcaatcccct
     8821 agcacatttg atcaaaccct ttgatgagga ggagctatat cggacaactc atttttcctc
     8881 tcaagccttt ctagatggtt tgattcgctt agcagttttt tctggtgtta actatatcaa
     8941 agagcccttc tattttgatg tcgttaatgc tgtcattgaa aaggagctgt tagacagcgc
     9001 caagccttag ctatttgaaa gattagcaat aataaaaaac ctgaacgatc tgaacgaggc
     9061 ttctctaagc tagctatgac tagtcagctt agagccttag aacaggtctt tcaggttttt
     9121 tatgtttagc tagtgtggtt aattaatgat tgaagctaat ttcttctagc aggtagtcaa
     9181 taaatcgctc tcccattttt gagaggttag ccttttcgtg cttgataaag acaatctcaa
     9241 tcacatcagg gacatctaag ggaatagcga caatctggtc tccatttaga tttgtgttta
     9301 aaataccgct ggcaacggtg tagccattta agccaatcat gagattaaat agagtagctc
     9361 ggtcactcac cacaatagac ttactgtgag ggatatgtgc catcatctcc tctgagaaat
     9421 aaaaggaatt gtgaatcccc tgatcatagc ttagataagg aaaatcaagg agatcatcaa
     9481 tggttaagct ggttttattt gccagaggat tggacttgct gataaagata tgcggtgtgg
     9541 ttttaaatag ggtggaaacg gtcaaatgat tttcctcaaa cagcttggta aggacgtctc
     9601 ggttgtagtc attgataaac aaaacgccga tttctgagcg aaaatttttc acatcgtcaa
     9661 tgatttccca ggttcttgtt tctcgcaaga aaagctcgta ctgggtcata tcagcccgct
     9721 ttaataaaga gacaaaagca ttgacaacaa aggcgtaatg ctgagaggaa acactaaaga
     9781 gctcacgact agtattgtga tttttatagc gatcctctag cagtgctgtt tgttcaataa
     9841 tttgtctggc ataagataga aactcaaccc cgtccttggt taaggtaatg cccttgggat
     9901 tacgaatgaa aatagtaatg cccatctcct gctctaattc cttgacagca ttagacagac
     9961 tgggctgcgt gataaataat tgcttagcgg cttcgttcat ggaaccgcat tcaacaatct
    10021 ttataatgta ttgtagttgt tggattctca tactgacagt ctatcttaaa tagtacaaag
    10081 aatcaagtgc ctttattaga gcttaagaca aggtttcaca agcggtagcc tagcttgtgc
    10141 ggtgaagcta gcttgatgct agtgttgtac ccaggtaaaa aagagctggc aaataggcag
    10201 ttttatcgct ttttaccgct tatttttggc atgcctgtgt tttgataaac ggctggtctt
    10261 gatcggtaaa aagtaatcgt gataatatca gataatacct atttttccat tgctctttta
    10321 attttcttgt gttatattaa taatattgat atatttaatg ttttgagata aagggtggtg
    10381 atggtgtaat atgactggac aaagtagtca tcaggtatta attcaaaagc tgttggtcag
    10441 cactcactat ttgacattat ttagagatga gctgaagcta gttgagagga caccatctat
    10501 tttgggaagt gagtttcctg tctctcttgt tcaaacggaa ttaggtgata ttatcacctt
    10561 ggtggatacc ttaaataagc agcagcgctt gattgagtcg accttttggt atgaggagtc
    10621 agcctttaag ctcatgaaca aggccttaga tattgttgat aattggataa aggggataga
    10681 tggcttaatt aagctctgcc agtccaagga ggtctttcag gccattgttg gtgataaaag
    10741 aacacgtgtt tttggtgttt tgattgatgt tttttcttcc ctaaaaatta gcaccatgtc
    10801 attgaaggaa tttgcagctc cggctgctct ttgccattag attaagctgg gctaagcttg
    10861 gatagtggct ggttaagcct gcaagttgcc cctctcatga caagtctagg ctttatttag
    10921 ggtgagcagt gtgccaaggg tgtattaagt gctggttgct ttgaagcttc gccttgctag
    10981 gttagctgtg agtgatgtca cgataactgc gcgaaacagt tatttctgaa ttataataca
    11041 ggttaaagta ggtactttta atgtttttcc tattgtaaaa tctatacaaa ataggatata
    11101 tttttgaaat agctgaacat taacgtacag caagctttat tttcttgcta aaaatctttt
    11161 ttataccttt gtcgtgtgag taatgtcaaa accctttgac aagggctgtc aaaaaagcta
    11221 taatgattga gataagttac ctttaagtga gtccagagag gcgagcaagg tacacaggat
    11281 aagatgagag ggtttgctct cttgattttc gtgtagcctc gcttctttgg aagtgaggct
    11341 tttatggtgt gactttcagt tggtctcgtg gtaatgattc ataagaccaa taaaccgctc
    11401 gttagacggg tgggcatgat ttgtttggga gtaccccaag ctgcatagaa aggataggtt
    11461 atgcgagaag aacgccctat tattgcctta gattttcctt cctttgagga ggtcaagtca
    11521 tttctgtcgc tgtttccagc tgatgagagg ctatacgtta agattggtat ggaactgtat
    11581 tatgctgaag gaccagatat tgtccgttat gtcaagtcct taggtcacag tgtttttctg
    11641 gatttgaagc tgcatgatat tccaaataca gtcaaatcaa cgatggcagt cctatcaagg
    11701 cttggtatag acatgacgac tgtgcaggct gctggaggtg tagagatgct tagagcagcg
    11761 cgtgagggct tggggcaggg tccgattctc attgcggtga cacagctaac atcaactagc
    11821 gaagagcaaa tgcgtgagga tcaaaacatt caatccacgc tgttagcatc tgtgcttcac
    11881 tatgccaagc gtaccgctca ggctaagcta gatggcgtgg tttgctcagc ccatgaggtc
    11941 aaggccatta agtcagaagt accagcaggc tttgtgtgtt tgacacctgg gattcgcccg
    12001 acaggtgctg acatcggaga tcaaaagcgg gtgatgacac ctcatcaagc tagagctatc
    12061 ggaagtgact atattgttct tggtcgtccg atcactcagg ctacagaccc tgtcaaggct
    12121 tatcaccaga ttaaggcaga gtggaaccgt tagcagcagg atcatcatga cacatatagc
    12181 tggactatga caccaaggaa aagaggagaa aaatgacact agcagcacaa attgcaacag
    12241 atttacttga gattaaggcc gtttacctaa gaccaaagga gccctttact tgggcgtcag
    12301 gcattacatc accgatttat acggacaatc ggatcaccct ttcttatcca aaaaccagaa
    12361 gcttgattga aaatggcttt gtggagacga ttaaggcagt atttccagag gttgaggtga
    12421 ttgctggcac agcaactgct ggtattccac atggtgctat cgttgcagat aagatggacc
    12481 tgccttttgc ctatatccgc agcaagccaa aggatcatgg agcaggcaac caaatagaag
    12541 ggcatgtgcg ctgcgggcaa aaaatggtga ttatcgagga tttgatttca acaggtggat
    12601 cagttctgga ggcggcagcg gcagctagtc gcgaaggtgc tgatgtacta ggagtggtgg
    12661 caatttttac ctatgaattg ccagtagcaa gcatcaattt tgaaaaggca gggctttcct
    12721 tggtgacctt gtctaattat tcagacctca ttaaggtcgc taaggccaag ggctatattg
    12781 atgctgatgg cttggccctg ttaaaaagat ttaaggagga tcaaaagcat tggcagcatg
    12841 agagttaaac agtgctgaaa agctgctgac atgctgacta tgtcttaagg agagaaaaaa
    12901 tgacttacaa agatttactt gagataggtg agaccagtta ttatcagacg gatcgcttga
    12961 cttactacaa aaatcctgtg gtatctgagc gctattttga taattacctt agctatcgta
    13021 gcatgccttc tttggctgat ttgaaaaagg acttggccta tgtggcaaaa gagcagcagg
    13081 attatcctag tcactacgcc tttctctttt ttgctgaaaa tgaagagcta agtacagaca
    13141 tgcgagctta tttgacagat catcacttta gccttgaaaa gcacctgatc tttaccaatg
    13201 agctggcaaa gcttcaccta aaggagcgtg atatatcacc agtcactatt gaacagctct
    13261 cagaaacaag cttttctgcc tatctggctt acaaatatca ggctaatttg gcttatggtg
    13321 aaacctatgc caatcaatgc aaggctgata atgaagccaa tctattgaca aacggctcaa
    13381 ccatttattt agccatcaag gaagggaaga ttatcggaga tattacggct tgggaatgtg
    13441 gcgactatat tgaaatggac gatttcagtg tagatgaggc ctatcgtggt cgtggtatcg
    13501 gtacagcctt acagcgtaag gccagtcaag gctataagaa ggtcattctc atctcagaag
    13561 aagctaatcg cgccatgtat gagcaccaag gctatcagga ggttgcttac tactggacag
    13621 cgctaaaaac atcgactaga taagtgataa agaaacagat tataggattg aaggtgtagg
    13681 ctcttatgag tatgactctt caatcctttt tttctgagcg catttgctaa tcatacctaa
    13741 tgaataagtc gtagcctgtc tagtggctca ttttaatggc gtcttgctct gttttatgat
    13801 taaatataga gaaaaagcta ttgttagggc atgcttgttg gtctagcaag gctgatggat
    13861 gataggatag ggaattgatg atttttaaag atgcaacaga aatggcgcag gctgttcgag
    13921 aaggtagggt gagcccctca gccttagtga gagacacaat taaaaaggct caagcactca
    13981 atcctgagtt gaatgctatt acctcagagc gtttttcaga agctcttgct gaggcagcag
    14041 caagggattt ttctggaaag ccatttgctg gtgtgcctat ttttctaaag gatttagggc
    14101 aggagcagga gggccaattg gccactgcag gatcagtgtt atttaaggat tatcgtgcct
    14161 caaaaacgga ttatgttgtg cagcgactag aggagctggg ctttattatt ttaggaagaa
    14221 gcaatacacc tgaatttggc tttaaaaata ttagtgatag tcgcttacat ggtccggtaa
    14281 atctgccaca ggacaagagc cgtaatgctg gtggttcatc aggtggggca gcagctcttg
    14341 tgtcctcagg aatcaccttg ctggctcctg ctagtgacgg aggaggatcc attcggattc
    14401 ctgcctcctt taatggcttg atcggtttaa agccaagcag aggaagagtg cctgtggggc
    14461 caggctctta tcgtggctgg cagggggcgt ctgttcattt tgctctaacg aggtctattc
    14521 gagacacaag tcgtcttctt tatcacttgc aggtttatca ggtagaaagc ccttttccat
    14581 tagtgccatt aaccaaagaa gagctttttc accctttaga cagaccctta aggattgctc
    14641 tttatgatca catgatagat ggaactaccg cctctataga tgctcagaca gctttaaccg
    14701 aggcctgtca ttttctaaaa gagatggggc atgaggttgt gcgattagat aagcttcctc
    14761 tagatatacc aaaggttatg agggattact acctgatgac tagtgttgag acagctgcta
    14821 tgtttgctga tagccaagaa gcccttggtc gtcaggtgac caaagcagat atggaggtca
    14881 tgacctgggc tatctaccaa gcgggtaagg atattcttgc ttcggtctat tctcaggcgc
    14941 tgcagcgctg ggaccattat agtgctgaaa tggcaagctt tcatgagcag tatgatcttt
    15001 tgctgacctt taccgccaat acgcctgctc caaagcatgg acagttccag ccaagcaagg
    15061 agctaataga taagctggct aaggcggaat gctacccctc cagtcagcgc ctagcgctag
    15121 tagaagccat gtttgagcag agcttgttca taacccctta cacagctttg gcaaatctga
    15181 caggccaacc agctcttagt ttaccaacct atgaaacgtc tgctggattg ccgatgggca
    15241 ttcaattgat agctgctaaa gggcgagaag acttattgct gggaatagct agacagtttg
    15301 aacgggctgg attgttaaag ctacctggtt aaatattata aaacagagct aatctattat
    15361 aggttagctt ttttgttaaa tcgagcatat ctagtctctt ataagattag tcaatgctat
    15421 actgtcatta ataatgaaaa aggagttctt gatgaaaaaa ggagttgctt tactttctgt
    15481 tagcttggcg agcttgctgt tagccgcctg tgggtcacag ccatcagctc aaaaaacaag
    15541 ctgggaaaag attaaagata aaggtgtttt aaaggttgct acgcctgcga cctaccagcc
    15601 aacatcgtac tataatgatg ccaatgaatt ggtcggctat gaggttgacc tgatgaagga
    15661 aattgggaaa cgccttgatc ttaaggtgaa gttcattgaa acaggctatg atcaggcttt
    15721 tacttcggtt gatagcggtc gtgttgatgt ttctctcaat aattttgaca ttacagccaa
    15781 gcggcaaaaa aaatacaaca tctcaacgcc ttataagtat ggtgttgggg gaatgattgt
    15841 tcgtgctgat ggcagctcag gcataagcaa ggctgaccta agcgattgga aagggaaaaa
    15901 agcagctggc gcctctggta cagaatacat gaaggttgcc aagaagcaag gtgctgaatt
    15961 agtcacttat gataatgtga cgggtgatgt ttacctgaac gatgttgcta atggcagaac
    16021 agactttatt cccaatgatt atcctgcaca aaagcttttt gtggattaca tgaagtctca
    16081 aaatcctaac ctcaatgtca aaatgagtga tgtgctgtat aatccgacag cacagggcat
    16141 tatcatgagt aaaaaagatg acacccttaa gaaaaagatt gatgcggtca tcaaagacat
    16201 gaaacaagat ggcagcttga aaaccatttc aaagacatac tatgctggtc aggatttgac
    16261 agttcctttt ggtaaggaca agaaaattcc agtcattgat gccagtgatg tggactagtg
    16321 ccttagacaa aggagctcta aagcgatgct taatcttaga ttgatactag agagcttggg
    16381 ctttgttttg tcaggtttgc cctatacctt aggcatttct tttttaagct ttctaacagg
    16441 ccttttgctg ggcttgcttt tagccttttt aaggcgttct actagtcact ttagtcatta
    16501 tctggtcagg agctatgtgt ccataatgcg tggcgttcct atgattgtgg tgctctttgt
    16561 cctttatttt gggcttccct attatggctt agaactgtct gccttgttat gtgcctattt
    16621 gggcttttca ctggttagtg cagcctatat ctctgaggtc tttcgtgcct cgattgatgc
    16681 tattgatcag ggacaatggg aggcagcaag ggctttgggg ctgccttatg tcagcattgt
    16741 caagcatgtg attctgcctc aggcctttcg tattgctatt ccgcctttag gaaatgttgt
    16801 gattgatatg gtcaaaagtt cgtctttggc agctatgatt accgttcctg atatttttca
    16861 aaaggctaaa attattggtg gcagggagtg ggattacatg tctatgtata tcttggttgc
    16921 ctttatttat tgggtgattg cctttttgct ggagcgctgt cagggctttt tagaaaagag
    16981 gctgcgctta ctctcttaaa aaccgaatat ttaccctaga aatattgtat ttctagggtt
    17041 tttatgataa aaatatgata gactaaagta gcctaatcag ttagttagct ttgtcaagaa
    17101 ctgactggct agagtgttgg aggtaggata tggcagactc tattgtattt cggaaaaatc
    17161 atatgatttc aactcaggcc tttgctcgag tgctggaagc ctcagggatt aaaagaccga
    17221 ctaaggacga ggctagatta tcgcaaatgc taaagcattc caattatcta tggacagcat
    17281 gggaaggtga caagttagtt ggtgttgcta gagcccttac tgactatgct tatgtctgct
    17341 atatttctga cctagcagtt gatcaggcat atcagggtca agggataggc aagcaattgc
    17401 tgtcttttat ctcagaggat cttggagatg ctgttgctct tgtattgctg tcagcacctt
    17461 cggcgatgtc ctattaccct aagcttggct ttgaacaatc agacaaagcc ttcattattc
    17521 cacgaaaacc gttttagaga ggtatctaat gacacattca gcttggcatg atgagattaa
    17581 gcaagtgtta cctaaggatt attatcggcg tatcaatcgc tttttagatg aggtctatgc
    17641 gactggagtg gtttacccgc ccagagacaa tgtgtttaag gccttacagg taacgccatt
    17701 agaagagaca agagtgctta ttttagggca ggacccttat catggccctc ttcaagctca
    17761 gggactttcc ttttcagtgc ctgactccat tcctgctccg ccatctttgc aaaatatttt
    17821 ggaggaatta gcagcagata ttggagtaag gaatcatcac gatcttagca gctgggctga
    17881 gcagggagtg ttgctcttga atgcctgctt gaccgttcca gaaggacgcg ccaatgggca
    17941 tgcaggtctc atctgggagc cctttaccga tgcggttata aaggtcttga atgctaagga
    18001 taggcctgtt gtgtttatcc tctggggagc ctatgcgaga agaaagaagg ccttgattac
    18061 taatccgatt caccatgtta tcgaaagccc tcaccctagc cctctgtcag cctatcgtgg
    18121 cttttttggc agcaagccct tttcaagagc taacgccatt ttagaaaaag aaggcctagg
    18181 acagattgac tggctgcgct aggcattgag gcaggctatt atggctaagc aggacgattt
    18241 accaataaag tatccggctt tggagacttg ggtataccta gctaaataga gattgatgat
    18301 atcagggatc aagacagtta cgtccgatat gtcaagcaaa acaaataatc actgcctaga
    18361 taaatcagaa attgctaggg ttatgcttga ttatcctgat aagcagataa gtagatttga
    18421 cataggaggg gtcatgttat taattaaaaa tgggcgtgtg atggatccaa aatcacagct
    18481 agatcaggtg gcagatgtct taattgataa tggaaggatt ttacggattg ctccagacat
    18541 tgagcatgat gaggtagagc agatcgatgc cagtggactt gttgttgctc ctggtttagt
    18601 ggatattcat gttcatttta gagagccggg tcaaacgcac aaggaggaca ttcatacagg
    18661 tgctctggca gcagctgctg gtggggtgac aacagtagtc atgatggcaa acaccaatcc
    18721 tgttatatca gatacggaaa ccttacaggc tgttctagca agtgctgcta aagaaaaaat
    18781 taacatttat accaatgcta gtgtgaccaa gcggttcaat ggccaagagc taacagactt
    18841 taaagcgctc ttagcagctg gtgcggtcag tttttctgat gatggcattc ctttagagag
    18901 ctccaaggtc ttaaaggaag cattggattt ggctaaggcc aacaagacct tcattgccct
    18961 gcatgaggag gatccccaat taaacggtgt ccttggcttc aatgagcata tcgctaagga
    19021 tcattttcat ttttgtggcg ctactggtgt ggcagaatat agtatgattg ccagagatgt
    19081 gatgattgcc tatgatcgac aagctcatgt tcatattcaa catttatcta aggctgagtc
    19141 tgttaaggta gttgcctttg ctcagcagtt aggtgccaag gtcacagccg aggcaacacc
    19201 gcagcatttt tctaaaacag aagacctttt acggcttgca ggggcaaatg ccaagatgaa
    19261 tccgcctcta agaacagaac aagatagatt agcagttatt gaggggctca aatcaggtgt
    19321 catagctatt attgcaacgg atcatgcacc acatcatcgt gatgaaaagg ccgttgctga
    19381 tctgaccaag gcaccatctg gaatgaccgg cttagaaacc tcattgtcat taggcctgac
    19441 aaatcttgtg gagccgagcc atctttcatt gatggcgtta ttagagaaaa tgaccattaa
    19501 tccagcctca ctatatagct ttgatgctgg ttatttggct gagtctggcc ctgctgatct
    19561 tgttattttt gctgacaagg aggagcgttt ggtaacagaa gcctttgctt caaaggctag
    19621 taattcacct tttattggcg aaaccctaaa gggagttgtg aaatacacca ttgctaaggg
    19681 acaaattgtt tatcaggcag acaactaatc aacacttaaa aagctgagca tctgatagta
    19741 actgatgctc agctttttga tttagtgatg gcttgcgggc tgctgcttgc ttaagttcaa
    19801 gccccaagga atgagatttt cagattgctg cttgattcgc ttcatattat cctgatgcct
    19861 taggataatg attgctgcta gcacaacgat ggtaatggtt aatagccaat cgtagctagg
    19921 caataaaaag tgggcggcag gaaaagtcag aacgctaatc acagctacta cagacgctgt
    19981 tagactagct agtgaaatca tgctaaataa ataaagcgtt agcacaaaca cagccgctaa
    20041 aaaaaggaga tagagtgggg caaagcctag caagacacca gcactggttg cgactgcctt
    20101 tcctcccttg aagccagcga aaataggaaa ggtatgccct aggacagcaa aaaagccaat
    20161 agtaattggt gagatattgc tagcgccaac caaaaccgga agaagcgtgg caagcgtgcc
    20221 cttaaaaata tcaatcaata aggttgcagc accagctttt agcccaagaa tccgaaacgt
    20281 attggtcgta ccggtattac ctgagccatg ctcacgcagg ttgatgttat agaaatactg
    20341 tccaatccat aagcctgttg gaatggagcc aagtaaatat gctgtaagaa ttaataggat
    20401 caatttcata acatacatta tatcataatg attgatttaa gcggaagcag ttacaaagaa
    20461 ttacgaaaaa atcttaaatt attttgcaaa attctcaaaa aacctgtaag ataaaaaaga
    20521 tgaaaacgtc tggaggtcaa cttggctaag aaagaaataa gcataacaaa ttataatgat
    20581 gatgccattc aggtcctaga gggcttagag gcagttcgta aaagaccagg gatgtatatc
    20641 ggatcaaccg atgcaaccgg acttcaccat ttgatttggg agattgtcga caatgctgtt
    20701 gacgaggcct tatctggctt tggaaatgag atcgatgtga cgctaaacaa ggatggttct
    20761 gccaccattt ctgacagcgg acgaggcatg ccgaccggac agcacgccct tggtatacca
    20821 actgttcagg tcatctttac catcttgcat gcaggtggta aatttggtca aggaggctat
    20881 aaaacctcag gaggcctgca tggtgtgggc tcttcagttg taaatgccct atcgtcatgg
    20941 ctagaggtgg aaatcacgag agacggagcg gtttacaagc agcgctttga aaatggcggt
    21001 aggccagtga caggcttaga aaaaatagct acagctccaa aaagcaaatc agggacaagg
    21061 gttactttca tgcctgatga caagattttt tcgacaactg agttcaagtg gaatactatc
    21121 gcagagcgtc taaaggaatc tgcttttctg ctaaagacgg ttaaaatgac cctgactgat
    21181 ctacgaggtg acgatccggt cgttgaggaa tttcattatg aaaatggtgt tcaggatttt
    21241 gttgcctatc tcaatgagga caaggaaacc ttgactcctg tgatttacat ggaagggcag
    21301 gagcaggatt ttcaggttga ggtcgctttg caatacaatg atgggttttc agataacatt
    21361 ttgtcctttg ttaacaatgt taggacaaag gacggtggca gccatgaaac tggcttaaaa
    21421 tcagctatta caaaggccat gaatgactat gcccgcaaaa ccagcctact aaaggaaaag
    21481 gataaaaact tggagggctc agattatcgt gagggcttgt ctgcagtgtt atcgatcctt
    21541 gtaccagagc agcatttgca atttgaaggg caaacaaagg acaagctagg aagcccactg
    21601 gcaaggccga tcgttgagag cattgtatca gaaaagctga ccttcttttt acttgaaaat
    21661 ggtgagctgg caggtcattt gattcgtaag gctatcaagg caagagacgc gcgtgaggca
    21721 gccagaagag cgcgtgatga gtctcgaaat ggtaagaaaa acaaaaagga caaggggctt
    21781 ctttctggga aattaactcc agcccagtcc aaaaatccta agaaaaacga gctgtaccta
    21841 gtcgaggggg actcagctgg aggctcagct aagcagggca gggatcgtaa atttcaggca
    21901 attctcccct tacgtggtaa ggttttgaac acagaaaagg ccaagatggc tgatattctc
    21961 aaaaatgagg aaatcaatac aatggtttat accattggcg caggtgttgg tgctgatttc
    22021 aatcttgatg atattaatta cgacaagatt attatcatga ccgatgctga tacggatggg
    22081 gctcatattc agaccctgct gctgaccttt ttctaccgtt atatgcggcc gctggttgaa
    22141 gcaggacatg tctatattgc cttgcctcct ctttataaaa tgtcaaaggg taaaggcaaa
    22201 tcggagaagg tttcctatgc ttggacagat ggtgagctgg aggatcttcg caaggaattt
    22261 ggtaaaggtg caagtctcca acgctataag ggacttgggg agatgaatgc cgatcagcta
    22321 tgggaaacca cgatggaccc tgacacacga acccttatcc gagtgacgat tgatgacctg
    22381 gctagggcag agcgacgcgt ttcagtcctc atgggagaca aggctgcccc acgccgtcaa
    22441 tggattgagg acaatgtcac ctttaccttg gaggaaaata cggtttttta aggcattttt
    22501 cctaaggagg gttctaaaat atctcatatc aaattgctat tcatgtgctc agcattcatt
    22561 tatcaaggat tgtaatcatt gaggtaacag tgatgaagct agatatttgt caacaaagct
    22621 acagtcttca gtggggaggc acctattatt ttgcattgac agattatccc aatatcaagg
    22681 cttgggaact ggaaaagcta gcagcctttt gtgcctacga aaaatggaat catcgtcaaa
    22741 cagacattag ctgtcaggac agcaagcttc ttgaagaggt tcatcaattt cttgaagcac
    22801 atgcttgtgc ctatctcttt aggcctagct gtaaattggt ggcttcaaca tttaacatca
    22861 atggagaggc agtctgttgt ccttatttaa gtcatacctg cactgtagcg gctgctctaa
    22921 gcatttttaa gacaggaagg ctattgtctg ctgtaagagc ttttggggta acggcacagg
    22981 agttggctag gagtgatcga aatgctgctg gtgatcctgc tgattatttt cattatgtga
    23041 tgcttggctg gtccaatacg acctcaggct atcgcttggc tatggagaga ttgcttaatc
    23101 gtatgccaaa tgaaaaggac ttaagagagc attttgtacc cggagttagc tttcactata
    23161 gctattctga tatttgtcag atgaaaggct atgtttttga tggctatcac cctgccaaga
    23221 tcaaagacga gcttagtttg gaggaattgc aggcttgcat tattcctaaa agctggcagc
    23281 agcgctttga agcaattatt ccaaaggcct tacgctcaag ggttcattac ctagactata
    23341 aaggcgaagg cttggtcgag tggtctgata gggtttatca gctgttaaga gtgatcagtg
    23401 acagctagct gtaaataggc tagctttata ctattttttg aatataatag acaatctaac
    23461 agaaaggaaa gctcagtgag aggtctcttg ctgggtgtgg gatggatttc ctagaaactg
    23521 ctaatcctag cgatagggga gcgtagcgag cccattctga aagctcctgc cgtagtgaaa
    23581 agaagataat cgcttacgat tatcttcgag ggaaatttcg agccgaagtc tcgaaattta
    23641 ggaatggaac cgtaggttcg cttctgtccc cactacctaa aggaactttc aaaaaaaact
    23701 aattaaagaa agagatatct ttctgaaaga aacaaagaaa ggaatgttca gctagtttac
    23761 taactgaaca cgggactatt tttcctagaa aaatcggtaa cctcctagtg tccaaggaca
    23821 cgtcgtcagt tccagcattt tttacggaaa aatttcgcaa gcgaaacgtc cctttgtatc
    23881 ttatgagtaa tattcaaaac atgtcccttg aggacatcat gggagagcgt tttggacgct
    23941 actccaaata catcattcag gagcgagcgc ttcctgatat tcgagatggt ctaaagcctg
    24001 ttcagcgccg cattctttat tctatgaata aggacggtaa tacctttgaa aagggctacc
    24061 gcaagtcagc caagtctgtt ggtaatatca tgggcaattt ccacccgcat ggagattctt
    24121 cgatctatga cgctatggta cgcatgagtc aggattggaa gaatcgtgaa attcttgtgg
    24181 aaatgcatgg caataacggc tcgatggacg gtgatccacc ggcagctatg cggtacactg
    24241 aggcaagatt atctgaaatt gctggttacc tgctacagga catcgataaa aaaacagtgc
    24301 catttgcttg gaattttgac gataccgaaa aagagccaac agtattgcca gctgcctttc
    24361 caaatctatt ggtcaatggc tcatcaggga tctcagcagg ctatgctaca gatattccac
    24421 cacataattt gtcagaggtg atcgatgctg ttatttatat gattgaccac ccaaatgcca
    24481 agctggataa gttaatggag ctattgccgg gtcctgattt tccaacaggt ggtattatcc
    24541 aaggagcagc cgaaattaaa aaagcctacg aaacaggtaa gagccgcgtt gttgttcgct
    24601 ccagaactga aattgaggat ctaaagggag gcaagcagca gatcattgtg accgaacttc
    24661 cttatgaggt caataaagct gtcctagtta aaaaaattga tgatgttcgg gttaataaca
    24721 aggttccaga catagcagag gtgcgtgatg agtcagaccg tacagggcta cgcattgcta
    24781 ttgagctcaa aaaagacgct gacagccaaa ccatcttgaa ttatttgttg aagtataccg
    24841 agcttcaagt caattataat tttaatatgg ttgcgattga tcattttacg cctcgtcagg
    24901 ttggattgca aaaaatctta tcaagctata tcgctcaccg caaaagtatt attatcaagc
    24961 gctctcagtt tgacaaggaa aaggctgaaa agagattgca tattgttgag ggcttgatac
    25021 gtgtcttatc tattttagat gagattatcg cgctgatccg agcttctgac aataaggctg
    25081 acgccaagga aaacctaaag gtcagctatg atttttcaga ggaacaagca gaggctatcg
    25141 taaccttaca gctttatcga ctgaccaata cagatattgt taccctccag caggaagaac
    25201 atgacctaag agagctcatc acaactctct ctgccattat tggtgatgaa gcaaccatgt
    25261 ataacgtgat gaagcgtgag ctaagagagg tcaagaaaaa gtttgcaggg ccgcgtttat
    25321 cagagctgca ggctgaaagc caagcgattg aaattgattc tgctagtctt attttggagg
    25381 aagaaacctt tgtcagtgtg actcagggag gctatatcaa gcgaacaagc cctaggtcat
    25441 ttcacgcctc aagccttgag gaaattggta agcgtgatga tgatcatctg atctttgtta
    25501 agcaggctaa gacaacagac cacctgttac tctttactaa tttaggtaat gttatttacc
    25561 gtccggtcta tgagctgact gacttgcgct ggaaggacat cggggagcat ttatcacagg
    25621 ctattgctaa ttttgctgct gatgagctgg tgatatatgc tgagttgatc cagtcctttg
    25681 aagagggact atatatctca gtgacacagc atggactgat taaacggttt gagcgcaagg
    25741 agctgacgcc ttggcgaacc tacaaatcaa aatcaattaa atacgccaag ctaaaagaca
    25801 tagatgatcg cattgtggca atagcaccaa ttatcatgga agatcttctt ttggtgacgc
    25861 agcagggcta cgccttgcgg ttttctagcc aagaaatacc gattcagggc ctaaaggctg
    25921 ccggagttaa aggaattaac ctaaaggctc aggattactt ggtttctgcc tgcccagtca
    25981 atgctgattc cttctttgtg ctgacgcaaa gaggagcact aaagcgagtg gcgattgctg
    26041 atattccaca gaccagccga gctaacagag gtctgccggt gttacgagaa ttaaagacca
    26101 agccacacag agttttcttg gcaggaatgg taaaaggaga tactacaaca ggtaccattg
    26161 acttatttac acatgattca gaggacacag ctagtgacca gcaattagag gttattagta
    26221 agactggtca acaataccag cttgctctca atagcctgtc tctatcagat aggacaagta
    26281 atggctcctt tatttcagag agcatttcag atcaggaggt cgctgctgca aggctcatct
    26341 agccaaagct ttttcgctgt accagtgagg gctctgagtc tttcatcgaa aaaagatgca
    26401 aaacaatgaa gaaaagaata caaaaagaaa agaggtagga taatgacaac agctattgat
    26461 tgggaaaact taggctttga ataccgtaag ctgccatttc gctatgtatc atattacaag
    26521 gacggcaaat gggacgcagg tcgcttaaca gaagatgcta ccctgcacat ctcagaaagt
    26581 gcaccagctc tgcattatgg gcaacaagcc tttgaaggct taaaggccta tcgcactaag
    26641 aacggctcta ttcagctatt tcgcccagac cgcaatgcag ctcgcttaca ggcaacagct
    26701 gaccgtttgc tgatgccaca ggtatctacc gagcaattca ttgacgccgt taagcaagtg
    26761 gtaaaggcaa atgaggattt tgtaccgcca tatggaactg gtgctaccct ttaccttaga
    26821 cccttgttaa ttggtgttgg cgatattatc ggtgttaagc ctgctaacga atatatattt
    26881 atagtttttg ccatgcctgt tggcaattac tttaaaggcg ggcttgcgcc gaccaacttt
    26941 atcgtctctg aggattatga tagagcagct ccttatggca ctggagctgc caaggttggt
    27001 gggaactatg caggtagctt attgccagga aaagcagcta agacagcagg gtattcagat
    27061 gtgatttacc tagatccagc aactcacact aagattgaag aggtcggagc cgctaatttc
    27121 tttggcatca ctgccaataa tgaatttatt acgccgctta gcccatcaat cttgccttca
    27181 attaccaaat actccttact ccaattagcc gaagaaaggc ttggtatgac cgctattgag
    27241 ggtgatgtgc cgattaatga tttggaccga tttgttgagg caggagcttg tgggacagct
    27301 gctgtgatct caccaattgg aggcattcag tatcaggata agctacatgt cttttacagc
    27361 gagactgagg ttggtccagt gacacgtcga ttatacgatg agctggtcgg tatccaattc
    27421 ggtgatatcg aagcaccaga aggctggatt gtagctattg attaaaataa gtgaagcttg
    27481 ctattgcaag ctcttttgat tttgtgtaaa atagacaagg cgaggtgaag tgatgagtaa
    27541 aaaagagaaa aaaattgaac tgcaattatg cgatcaacaa gtaacagtca acaataccaa
    27601 gatagacggt tatcagttac aaattggcaa gcgtgtcgtt ggcgagattg cagagcttga
    27661 tggcaagttt gctgtcttaa aagacagcac agtagatgct ttttttaaaa cattagagca
    27721 agcagttgaa aatattattg aaaactataa tttgaaccac taaaaatgct taaaaagact
    27781 tgtcagctta caaaaactat ggtagaatag tttttgttgt tacggaaaga tagcgaagag
    27841 gctaaacgcg gcggactgta aatccgctcc tttgggttcg ggggttcgaa tccctctctt
    27901 tccatgccta agctattagg ttcattgttt taatgatgat attggggtat agccaagcgg
    27961 taaggcaagg gactttgact ccctcatgcg ttggttcgaa tccagctacc ccagtcagag
    28021 gtatcagatt agcgtctgag atcgtcaagg ataaaagttg ttgtcattgc gggttacctt
    28081 gagaaaatat attgttatca aaagctagca taagctagct tttgttggag gattttttag
    28141 aatgaatgaa tttgaagatt tgctaaacag tgttagcgaa gtcaatcctg gtgatgttgt
    28201 cactgcggag gttttgacag ttgataacgg tcaagcaaac gttgttattg aaggcacagg
    28261 tgttgaaggc gttttgacac ttcgtgaatt gactaacgat cgtgaagctg atattaatga
    28321 ctatgttaaa gctggcgaca ccgttgaagt gcttgttctt cgtcaagttg taggtaaaga
    28381 tactgataca gttactttcc tagtatctaa aaaacgtttg gaagctcgta aggcatggga
    28441 caagcttatt ggtcgtgaag gtgaagtcgt tactgttaag gggactcgtg ctgttaaagg
    28501 tggactttca gttgaatttg aagggcttcg cggatttatc cctgcttcaa tgattgacac
    28561 tcgttttgtt cgcaatacag aaaagtttgt cggtcaagaa tttgacgcta aaatcaaaga
    28621 agttgatgca gcagaaaacc gctttatctt atcacgtcgt gaggttgttg aagaagcagc
    28681 taagcaagca cgtgacaaag tcttttcaac actttcagaa ggttcagtgg taactggtac
    28741 tgttgcgcgt ttgacaagct ttggtgcttt tattgatctt ggtggtgttg acggtcttgt
    28801 tcacgtaact gagctctcac atgagcgtaa tgtgtcgcct aaatcagttg tttctgttgg
    28861 tgaagaggtt gaggtgaagg tacttgctct tgatgaggaa gcaggtcgcg tatcactatc
    28921 acttaaagca acaacacctg gaccttggga tggcgttgag caaaagcttg cacaaggtga
    28981 tgttatcgaa ggtaaggtta agcgcttgac tgactttggt gcttttgttg aggtattacc
    29041 tggaattgat ggacttgtac acatttcaca aatctcacac aagcgtgttg aaaatccaaa
    29101 ggacgtgctt actgtaggtc aagaggtaac tgttaaggtt cttgacgtta acgctgctga
    29161 tgagcgtgta tcattgtcaa tcaaggcact tgaagagcgt ccagcacaag cagagggtga
    29221 aaaggaagaa aaacgtcaat cacgtccacg tcatcaaaaa cgtgaagcta agcgtgatta
    29281 tgagcttcca gaaacacaaa ctggattttc aatggctgac ctttttggtg atattgaatt
    29341 ataatactat aaaaa
//
LOCUS       DARYXS010000015        28033 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.015, whole genome shotgun sequence.
ACCESSION   DARYXS010000015 DARYXS010000000
VERSION     DARYXS010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28033
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.015"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(298..813)
                     /locus_tag="TV193_000541"
     CDS             complement(298..813)
                     /locus_tag="TV193_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1512768.1"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAIIPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLIHIGVDTVELGEAAF
                     SSDIVAGQEVVAGQLLAQVSLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAARA
                     EVGQVRLKATL"
     gene            complement(815..2326)
                     /locus_tag="TV193_000542"
     CDS             complement(815..2326)
                     /locus_tag="TV193_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1512769.1"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTDLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTNTQSSSLREVSLAIIEALGGQANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            complement(2316..3041)
                     /locus_tag="TV193_000543"
     CDS             complement(2316..3041)
                     /locus_tag="TV193_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL1512770.1"
                     /translation="MLEKPSKAELLTALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQAPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRSIRKKYPEQLFMADISTLEEGLVAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALKKEEKSHGF"
     gene            complement(3570..3992)
                     /locus_tag="TV193_000544"
                     /pseudo
     CDS             complement(3570..3992)
                     /locus_tag="TV193_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678587.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4136..4642)
                     /locus_tag="TV193_000545"
     CDS             complement(4136..4642)
                     /locus_tag="TV193_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512771.1"
                     /translation="MTQTFFNNDVDERRRQLYLDARSKGHLEKCFRGDSGFKINAKDS
                     YFQSITDINVLIERCLYPLYDLGDSIIPHETERILSQFSTSKNVVELYQVVSYIFYQK
                     NNKLLKKNFSFYIDFNPMIPDLVFSVKRLSPENIVTDDEKAMVGFIKNMFQKIPQVQS
                     YLEAQNCK"
     gene            complement(4644..5570)
                     /locus_tag="TV193_000546"
     CDS             complement(4644..5570)
                     /locus_tag="TV193_000546"
                     /inference="COORDINATES: protein motif:HMM:NF019104.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512772.1"
                     /translation="MNEPIAARVTKPTYNRQQLLKNLENSRLATESSRFKSYVAREKL
                     INTLRKQNADLNLITFREKAIEIFNRDLKGNSWVSIRQADEFVETLDDYAQLSVDNGA
                     VSTKADFYKMYSNKNYIYLDGFIKNIKQLYIKTGASSIVNGQDLYNAIEQYGTIGRGK
                     SGNFATSMAEDIALLYDSSGNLVSSGMIEAIKGVDEGKYLSGAFQYEYSPQFVKSFDQ
                     IGEVRTVTGKTPGSSLLNIPGAKTWAGKNMALSQSELMMPSIDTSNLKLEDVLLSMES
                     TGIYTLNNPTIVLKDGTKKIVEGQFIIRKLGN"
     gene            complement(5712..6134)
                     /locus_tag="TV193_000547"
     CDS             complement(5712..6134)
                     /locus_tag="TV193_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512773.1"
                     /translation="MEHSQLEWEDVSQYEEVKGYGQQVWKRQGTYYLVTNEGGIAEQR
                     VVYELPYDLFELLEQGKRNLGEIAFKLRYDCWPPTEEEKIASDKAFLQRSPIALIADP
                     TSWELFTQEELRKLIPIAEQKWIDWKGKLPDDYVSPLK"
     gene            complement(6457..6717)
                     /locus_tag="TV193_000548"
     CDS             complement(6457..6717)
                     /locus_tag="TV193_000548"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512774.1"
                     /translation="MDNNNCFQYTQRLRELIELEYPKQKNYSGILRDLYVLTNDIDNN
                     RIVGNINFSSLARQFVDDTTQYDSPILKTLKDLEVCLNRKRR"
     gene            complement(6732..8540)
                     /locus_tag="TV193_000549"
     CDS             complement(6732..8540)
                     /locus_tag="TV193_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512775.1"
                     /translation="MSYNIKYDEITSLQQSTQTTISAWGDGITSIQTALSALIGDSRL
                     QGQTASSIKSYLSEVHGTLLQTLQSLMNDYSASLLLYKDGYYQIDSNSHAQLPGQVFK
                     TLQSELRLSQAHLKDQLELLQNTRAKLSDLVHYSGVSHAKTVVDYSELITDIHRLDEA
                     IIQYESNHASQDLAAFKELLASTKALIAEYSSKPKRAGSYQVGDIGQLNTIKRFATAY
                     QGVARHLETNAKRLQAAQERDHARFEAVAAEDRAKQGWIDLALSLVTIAVGVAAIVMT
                     AGAATPLVVGAFVVGSGTVAYGASNLYEAGHNIYLGSVGDGLTVATNPLRDTLFMGND
                     RLYHQIGGLFTTASAALILIGQTKSVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSE
                     QDAQRATLVGNILAGYAASSAARRFSLNEPIAARVTKPTYNHQQLLKNLENSRLARES
                     SNFGGYIKKESVTKYPTQIDSKVTVGAKENLPGWIADSFTDSHYRTVITGEEITLYRT
                     FGGASDAGGGFVTTVPATNRIQAKIDTALLPEWKNTRQYEAVIKIPKGSQLNIGKVAP
                     QTVKSSGTTLIGGGDQVLLPNRWPLEWIQEIRIVPN"
     gene            complement(9181..10080)
                     /locus_tag="TV193_000550"
     CDS             complement(9181..10080)
                     /locus_tag="TV193_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEL1512776.1"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRSVPEEINRQNAPVINPDEVELEEMKAVRSQDRRA
                     AESDAHQPTGPLSTAQSAPTQSKAQPVSSAAGASQLDPAAADMSKDIELAAQEISDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
     gene            complement(10092..10901)
                     /locus_tag="TV193_000551"
     CDS             complement(10092..10901)
                     /locus_tag="TV193_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1512777.1"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLTRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPVFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TV193_000552"
     CDS             complement(10885..11244)
                     /gene="rnpA"
                     /locus_tag="TV193_000552"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEL1512778.1"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHVLMELGDHLKSEDFVVIARRGAEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            complement(11736..12476)
                     /locus_tag="TV193_000553"
     CDS             complement(11736..12476)
                     /locus_tag="TV193_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1512779.1"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            complement(12480..13778)
                     /locus_tag="TV193_000554"
     CDS             complement(12480..13778)
                     /locus_tag="TV193_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1512780.1"
                     /translation="MLGMSFFYALIFVNSWVIFSTFSGIKLAVRSLLLVGACFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDIGLLMVCHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFFKIYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLSQRLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDSGDIAAISKVYQTVIQESA
                     SSIRQLTPELSALDNVQDSVIRSLLHAKLLEAKLQGIAVYIDIPETLASSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            complement(13790..15136)
                     /locus_tag="TV193_000555"
     CDS             complement(13790..15136)
                     /locus_tag="TV193_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1512781.1"
                     /translation="MTDIYYLFLLLSLMIYYVTEISIFSFLSDIKLALWKQIFVLTAA
                     LFLNQFALLPPLIIDPLLLLAVLALEKRPCFSLKALFLAFVPGVFVDLLSRFILAIVL
                     PYIFSVNGSYVRHLVLDFIAYVMIFPSFALINYFVGKDYKQIVKADRFDKASSFYSLF
                     LLFSLAYYIDLFMILGFTDPFLDLKSPIMMSTSYKVLFLIFTLLLIYLLSYFNHQSKE
                     FLKQELKKEQQAYIANLETYGKHLEKLYKGVKVFQLVYLKRLERLGQAIDSGSVSDVQ
                     TVYAQTVDEATDYWDDKHYNISKLSKISVSSIKSLLSSKIIKAEKAGIALSLEVPDRI
                     RDSYISELDLLLLVSIFCDNAIEAALETAQPAVAIAYFLSDDQQIFTVTNTTKDERVM
                     ISRIFEEGYSSKGSGRGIGLSNAKRILQKYPELSLRTRSHDYQFSQTLIMPKIEKE"
     gene            complement(15581..17026)
                     /locus_tag="TV193_000556"
     CDS             complement(15581..17026)
                     /locus_tag="TV193_000556"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEL1512782.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSAYEKAAYIAEREAAGIVPTVRLAV
                     NEAGVYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDEIRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
     gene            complement(17628..18341)
                     /locus_tag="TV193_000557"
     CDS             complement(17628..18341)
                     /locus_tag="TV193_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEL1512783.1"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGFMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGGH"
     gene            complement(18469..18975)
                     /locus_tag="TV193_000558"
     CDS             complement(18469..18975)
                     /locus_tag="TV193_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEL1512784.1"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILQQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            19358..19636
                     /locus_tag="TV193_000559"
     CDS             19358..19636
                     /locus_tag="TV193_000559"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512785.1"
                     /translation="MKQTKIICLLAAAAVLTLGPISTGQTQPQTVYASQVSGDSCIDL
                     GNGWFKCPKDIGGWDILFNQDYQAPSRSPFFTWISGWFNFIWQWFKSF"
     gene            complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TV193_000560"
     CDS             complement(19797..21158)
                     /gene="radA"
                     /locus_tag="TV193_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEL1512786.1"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHINGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGDIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDLPKGIEVVGVTTVGEVLKA
                     VFT"
     gene            complement(21225..21671)
                     /locus_tag="TV193_000561"
     CDS             complement(21225..21671)
                     /locus_tag="TV193_000561"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEL1512787.1"
                     /translation="MTRIRGFELVSGFTDTDLLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQ
                     MKNITDQTITLSAGERIVQGVFMPFLIADGDQAGGERTGGFGSTGG"
     gene            complement(21873..22640)
                     /locus_tag="TV193_000562"
     CDS             complement(21873..22640)
                     /locus_tag="TV193_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEL1512788.1"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKVWARESIRPRILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFVKTVRGLEKESEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAANI
                     QGIDLVQVKKDAKAFMADKDLEADFPRIRFSYAGKEI"
     gene            complement(22802..24598)
                     /locus_tag="TV193_000563"
     CDS             complement(22802..24598)
                     /locus_tag="TV193_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512789.1"
                     /translation="MKILRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLAYLFTAVANLIYSLLFTR
                     VISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQQDAIDGFIEHNERVRAATFKGRLFAGLLFPVMNGMSLLNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGAGRI
                     QEMFDEKEEVRPEHAPVFTALKEGVEIKHVDFGYLPGQKILSDVSISAPKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQKEVETAARATHIHEFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGSHHELLRQKGFYAELYHNQFVFE"
     gene            complement(24598..26307)
                     /locus_tag="TV193_000564"
     CDS             complement(24598..26307)
                     /locus_tag="TV193_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512790.1"
                     /translation="MLRNAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DQTRIAEVGFWLLVIAGIGLVSGAVNTILSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMSQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDTFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIYLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PSISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            complement(26300..26749)
                     /locus_tag="TV193_000565"
     CDS             complement(26300..26749)
                     /locus_tag="TV193_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1512791.1"
                     /translation="MPRIIAELRELTHQVEQISEEIAKKYDLQHLAGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIRVVASATDKRCKQVVLTSAGRAK
                     LPVLKECRRDIERYFFKEISREELLTVKKVIDQLKQNIRAYKGDTDA"
     gene            26959..27978
                     /locus_tag="TV193_000566"
     CDS             26959..27978
                     /locus_tag="TV193_000566"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1512792.1"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     RHTNSHYFKDIVLDEAIKATLDLKEALADIDAILFVVPTKVTRLVAKQVAQVLDHKAI
                     VMHASKGLEPGTHERLSTILEEEIPAQLRSEVVVVSGPSHAEETIVRDITLITAASKD
                     ITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     NNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWHT"
BASE COUNT         8373 a         6755 c         5154 g         7751 t
ORIGIN      
        1 ctctattttc ctttttcagc ccttgtatac tggggaggat ataatagccc ccctaaaata
       61 aaatgtgcta agcaatatga gaaacaggtc gctgagcttt tcttttattt gccacaaggc
      121 acatacgaca gctgttaaca tttaaataga ggttaaaaga taggacaatc aaagcctgct
      181 gattgctgac aataataaaa gcaccccaag gcattgaccg acttagccaa gtgctggggt
      241 gcagtttttt catatgacct tttagttgtc atcaaggact ggatcgatag cctctagcta
      301 gagagtagcc tttagcctaa cttggccgac ttctgcccta gcagcaactg ctccagcatc
      361 agcaagacgc atatcagcaa tgtcctgtga gtttgtaaag acaaccataa cggtgctgtc
      421 tttttgagca gcttcaagca ctggcaaaga gacctgagcc aataactgcc cagctactac
      481 ctcctgacca gcaacaatat cagagctaaa ggcagcttct cccagctcaa cagtatcaac
      541 accgatatga atcaagacct caagaccagc tggagtaacg atgccataag catgcttggt
      601 cggaaaaacc gtcatgaccc ttcctgttac gggtgcataa atagcgccct cctgaggaat
      661 aatagcaaag ccatcgccca ttagcctttc tgaaaagaca ggatcactga cactggtaat
      721 aggaactaat tgtcccttag ccactgataa aatacgatcg cttaacgcat cagctttttt
      781 tgctgataat aattgcttcc acttctttat catgttaatc ttctctacct aatagttgat
      841 tgatttcttg actatacaag atagccttac caccataaat agcctgaatg ccatttttaa
      901 catctaatac agctgttgct cccagtgagg ttaaaacatt cttgttaacc aagctgctat
      961 ctgacagaga cactctcaag cgagtcgcgc aagcggttac atcttcgatg ttagcttgtc
     1021 ctcccaaagc ctcaataata gctaatgaca cctcacgaag tgatgagctt tgagtattag
     1081 tagtctctgc ttgtccttct gcttctacct gagctaccat tcccggtaca gcaacctgga
     1141 atttgctcac aaagaattta aagacaaagt aataaaccat aaaccacacg ataccaacag
     1201 ggataacaag tagccagttg gtatgatcat ttccttggaa cacaccaaag attaaaaagt
     1261 caatcaaacc acctgagaag gaattaccga tacgaatctt taataaatca gcaactaaga
     1321 aagaacaacc atctaagaaa gcatgaacta catagagcca aggggctaca aataaaaagg
     1381 caaattcaat aggctctgtg atccctgtta gtaaggaagt caaggcacta cttgaataaa
     1441 agctaccaac ctttttacga ttagcctttg gaatagcgtg atacatagca agacaggcag
     1501 caggtagtcc aaacatcatg gttgcaaaac gtcctgcaaa aaagcgtgtc ccgtaagtaa
     1561 acaagtcggt atggttagca tcagccaatt gcgcaaagaa gatattttgt gctccttgga
     1621 tagtctcacc tgctacaacc tcactaccgc caagtgatgt ataccaaaac attgggtaaa
     1681 tggtgtggtg cagccctact gctcctgtca gacgtaaaaa gaaaccgtac aagaatgttc
     1741 cgatgctccc catatccgca attttttcac caaacactac taggagattt tgaataggtg
     1801 gccaaatgac atagaaaaca ctaccaatca caatcgctgc caatgaggaa acaatcggaa
     1861 taaaacgaga gccgccaaag aagcctaaaa aggctggcag ttcgatcttt cggtacttat
     1921 tgtgaaggct aacaacaact aagccaaccg tcaaagcccc taaaacaccc gtatcaatct
     1981 gagcgtcctt tgctgaaaaa agagtcagat agccgctaat ggttgccgta aagaccaaat
     2041 aagccacagc acctgaaaga ccggctgttc ctttatctcc gttggctaag ccaacagcaa
     2101 caccaatcgc aaaaatcaag gcaatattag caaaaacagc gttacctgct gtgctcataa
     2161 tggtaaaaat agcctgtagc catgcttgat ttaatatcgg aaattgtgca atggcattgc
     2221 tatttgacag ggccccacca atccccaaca acaaaccagc aactggtaag attgagatcg
     2281 gcagcataaa ggcttgaccc aattttgaaa atttcttaaa atccatgtga tttctcctcc
     2341 ttcttgagag ccgccacaaa gcgctctgca atttcctttg gtctggtaat agcaccacca
     2401 accacaatac cagctactcc caaagcctga acagccctgg cctcctctgg actatgaatc
     2461 ttgccctcag ctatcactga tacccctgca tcacacaagg cacttatcag ctccatatcc
     2521 ggacctgtcc cctgacgact ataaggcgta taccctgata aggtcgtccc tacaaaatct
     2581 ataccagcct cataggctac tagaccctct tcaagcgtac tgatgtctgc cataaacagc
     2641 tgctctgggt acttcttcct tatcgatcga ataaagtccg ctatcgctaa gccatcatga
     2701 cgctcccttt gcgtacaatc caaggctatc accgctacat ctaaggccgc taaggcgtct
     2761 acctctgcca tggttggcgt gataaagggc gcttgcggag gatactcctt tttgatgatc
     2821 cctatgattg gcagatccgt caccgcttgg atttccttaa tatctcgaac cccattagct
     2881 cttatcccta ctgctcctgc ttcctctgct gcctttgcca tcagaggcat gatacctcct
     2941 gcctctgaat agagaggctc gcccggcaga gcttgacagg aaacgatcag cccgtctttc
     3001 agagctgtca gtagctctgc cttgcttggt ttttcaagca tgctttctac tccttttatt
     3061 aattttagag aacgttcaca tctttattgt agcagatatt aaaacacttt caatagatag
     3121 cccactttta ggaagtactt tcattttcag agaaaaatcc ttgttttctg aaagtatatt
     3181 caatagcctt aagtatggca aagagctagc ctattgagct atttactaat tgatacaaca
     3241 acagcaaaac cttacaagac ataccttctt accataaaag cctttttgcc agccagctaa
     3301 ggccaaatac ggcaatatgt ctcaacaaga actaccttag gtcctattat tgcttgataa
     3361 gcttgacaaa gagacaaaaa agagagaacc agtccagtcc tctctcgcac ccagcttttc
     3421 aagctctaca atacccgtag tgggtaactc caccgcaagg gttatatata gaacttttga
     3481 ttgtacccaa aaataaccac ttttcaccta cctaatacag ctaacaacgg cccctaacat
     3541 agctgccctc agatccgcta tcttaaacat tatttcaaag gactgacata atcatctggc
     3601 agttttccct tccaatctat ccatttttgc tccgcaattg gaattagttt tcttagctct
     3661 tcttaggtaa acagttccca actggttgga tctgcaatta atgctattgg ggatctttgt
     3721 agaaatgctt tatcactagc tattttctcc tcttctgttg gcagccagca gttatttttg
     3781 acataaaaat ctatttctaa taaaaatttt cggtcacttt ccagtaattg gaaaagctca
     3841 ttagggagtt tatacactac tcgttgtaca gcaattcctc cttcttctct gactagataa
     3901 tattctccct gatgcttcca aacctgttgg ccataaccct tgatttcctc atattgacta
     3961 acatcttccc atgttaattg actgcgtgcc atgtgtgtta tctttcgttt ttatagctta
     4021 atcgataaat actgctcaat ctttttccaa taataccctt acctcgtctg attgaaaagc
     4081 atactctatt tttatttaag ctatttcaaa tccatttttc aagtattcat ctaaactatt
     4141 tgcaattttg agcttcaaga taagactgta cctgaggaat tttttgaaac atgtttttta
     4201 taaaaccaac catcgctttt tcatcatcag tcacgatatt ttcaggagat aaccttttaa
     4261 cagaaaaaac taaatcaggg atcataggat taaaatcaat ataaaaggaa aagttcttct
     4321 ttagtagttt gttgttcttt tgatagaaaa tatatgacac aacttgatat aattctacaa
     4381 cattttttga agttgagaat tgagacagta ttctttcagt ttcatgtggg ataatgctat
     4441 ctcctaaatc atacaaggga tacaagcagc gctcaataag cacatttata tctgtgatcg
     4501 attgaaaata tgagtcttta gcatttattt taaacccaga atcccctcta aagcacttct
     4561 ctaagtgtcc ctttgaacga gcatctaagt aaagttgtcg acgtctttca tcaacgtcat
     4621 tgttaaaaaa tgtttgtgtc atattaatta cctaattttc taattataaa ttgtccttca
     4681 acaatctttt tagtgccatc tttcaaaacg attgtaggat tattcaaggt ataaattcct
     4741 gttgattcca tacttaataa tacatcctcc aattttaagt tactagtatc aatagatggc
     4801 atcattaatt cagactgtga caaagccata tttttacctg cccaagtttt agcccctgga
     4861 atatttaaaa gtgaagaacc tggagtttta ccagtaactg ttctcacttc accgatttga
     4921 tcaaaagatt taacaaactg aggactatat tcatactgaa atgcaccaga caaatactta
     4981 ccttcatcta cccctttgat agcctctatc ataccggaag aaactaaatt accactacta
     5041 tcataaagta atgctatatc ttcagccata cttgttgcaa aatttcccga tttacctctt
     5101 ccaatggtac catattgctc aattgcatta tacaaatctt gaccattcac aattgatgat
     5161 gcacctgtct taatataaag ctgttttata ttctttataa agccatctaa atatatatag
     5221 ttcttatttg aatacatctt ataaaaatct gcttttgtag aaacagcacc gttatctact
     5281 gataattgag cataatcatc taatgtttct acaaattcat cagcctgtct tatcgaaacc
     5341 caactatttc ctttaagatc cctattaaaa atttctatgg ctttctccct aaatgtgata
     5401 agatttagat cagcattctg ttttcttaaa gtattaatta acttttctct tgctacatag
     5461 ctcttaaacc ttgagctctc tgttgccagc ctgctgtttt caaggttctt caaaagctgc
     5521 tggcggttgt aggtcggttt cgtcacccta gctgctattg gctcattcaa gctaaaccgt
     5581 ctggcggcgc ttggagacgc ttggcattgg cttcaaggtg acgagctact ccctgataag
     5641 ctgtcgcagg ctaattatta agaacatgct ttaaaatagc agagctaatc tcggctccgc
     5701 tatcttaaac attatttcaa aggactgaca taatcatctg gcagttttcc cttccaatct
     5761 atccattttt gctctgcgat tggaatcagt tttcttagct cttcttgggt aaaaagttcc
     5821 caacttgttg gatctgcaat taaggctatt ggggatcttt gtaaaaatgc tttatcacta
     5881 gctattttct cttcttccgt tggtggccaa caatcatatc gcaatttaaa agcaatctcc
     5941 cctaaattcc gttttccttg ctccaataat tcaaataaat catacggcag ctcatatact
     6001 actcgctgct cagctatacc accttcatta gtcactagat agtaagttcc ctgacgcttc
     6061 cacacctgtt gaccataacc cttgacttcc tcatattgac taacatcttc ccactctaat
     6121 tgactatgtt ccatgtatgt tctcctttac ttgtactgat atctttcata actccctctg
     6181 gcatatcacc cggataagta cgacctccag gtcgccacca gctattagca cccttttcat
     6241 taccacttgg aatagaaatc cctttctccg aaacaacctc tggtgaaaca tctaagcgat
     6301 agagcggatc attgccaaga taaccctcgt cgaagccgag taagctttca taaaagattg
     6361 atgcatagtc agcttactct tgttcctcct ttcttcagtt ttttatcata atttcatctt
     6421 aaaatttaat caattcgagc aatctaatct cactcatcat ctccttttcc tatttaggca
     6481 tacttctaag tccttcaaag tttttaaaat tggactatca tactgtgttg tatcatcaac
     6541 aaattgtcta gctaaacttg aaaaattaat attcccaaca atccgattat tatcaatatc
     6601 attagtcaaa acataaagat ctcttaatat tcctgaatag tttttttgct tgggatactc
     6661 aagttctatt aactctctaa gcctttgtgt atattgaaaa cagttattat tatccataaa
     6721 tttctccttt tttagttagg aacgatcctt atttcttgaa tccactccaa tggccaccga
     6781 ttgggaagta agacctgatc tccacctcca attaaggttg ttcctgaaga tttaaccgtc
     6841 tgtggggcaa ccttgccaat attcaattga ctcccctttg gtattttaat tacagcctca
     6901 tattgtctag tatttttcca ttctggaagt aaagctgtat ctatttttgc ttgtatacga
     6961 ttagttgcag gcaccgttgt gacaaaaccg cctccagcat ctgacgcccc tccaaaagtc
     7021 ctataaagtg ttatttcctc acctgtaata actgttctat agtgactatc tgtaaatgaa
     7081 tctgcaatcc aaccaggaag attttcctta gccccaactg ttactttact atctatttga
     7141 gttggatatt ttgtaacact ttcttttttt atatagcctc cgaaattaga actctctctc
     7201 gccagcctgc tgttctcaag gttcttcaaa agctgctggt gattgtaggt cggtttcgtc
     7261 actctagctg ctattggctc attcaagctg aaccttctgg cggcacttga ggcggcatag
     7321 cctgctagga tattccctac caaggtagct ctttgggcat cttgctcact gccgcctaag
     7381 agcttggtgc catgatagct ggcctgacca ccgataaagc cgccaacctc accgatcgta
     7441 aactctgtca agcccttggc aacactcttg gtctgaccaa tcagaattag tgctgcactg
     7501 gctgttgtga acagcccgcc gatctggtga taaagcctgt cattccccat gaacaaggta
     7561 tcccgaaggg gattggtagc cactgtaagc ccatcgccaa cgctacctag ataaatgttg
     7621 tgcccagcct catacaggtt cgacgcccca taagcaactg taccactgcc aacaacaaag
     7681 gccccaacca ccaagggagt cgctgcccct gctgtcatga cgatagccgc aaccccaacc
     7741 gctattgtca caaggctgag tgctagatct atccagccct gcttggccct gtcctctgca
     7801 gctactgcct caaaacgggc atgatcccgc tcctgcgctg cttggagacg cttggcattg
     7861 gtctcaagat gacgagccac cccctgataa gctgtcgcaa agcgttttat ggtgttgagc
     7921 tgtcctatat ccccaacctg atagctccca gcccgcttgg gcttactgct gtactctgct
     7981 atcaaggcct tggtcgaagc caaaagctcc ttgaaggcgg ccaagtcctg actggcatga
     8041 ttgctttcgt attgaatgat ggcctcgtcc aagcgatgga tatcagtgat cagctcacta
     8101 taatccacta ctgtcttggc atgactgaca ccagagtagt gaaccaggtc tgataactta
     8161 gctctggtat tctgtagtag ctcaagctga tccttgaggt gggcctgcga gagccgaagc
     8221 tctgactgca gggtcttaaa gacctgaccg ggtaactggg catgactatt actgtctatc
     8281 tggtaatagc cgtccttata cagcaagagg ctagctgagt aatcattcat caggctttgc
     8341 agggtttgta aaagtgtccc atgcacctca ctcagatagc tcttgattga gctagcggtc
     8401 tgaccctgaa ggcgactgtc tccaatcaag gctgacaggg cggtctggat actcgttatc
     8461 ccatctcccc aagcactgat cgtggtttgg gtgctttgtt gaagggaggt aatctcatca
     8521 tatttgatat tatagctcat ttcttcccct aacgttttca atgcgatatc aaaatgtttc
     8581 accaataata gcaatacatt tctttaatat acctctttta ttatatcaaa aaaaacttaa
     8641 tgattatcac accaagctaa gagcattgat gggtaataac atatagctta tccaaccttg
     8701 ttagcaggag tattacaaat aatgtattgc caagaggaaa agctgatata aataggtggg
     8761 acaaacgtgg tcaagaaaac ctttaacacc aagaaaacca tgataattct tgataacatc
     8821 aaatagtgcc tcagctaaat gattatgatg acctttacca aatcattctt tattatctgc
     8881 aagaaaagaa cagtgacatc tcttcgatcc gattacgaat ataaatcaag cttcaaaacc
     8941 gctcttagta cctttattcg ttgccaaaaa tatctcattg aactctctta ttcaaacgct
     9001 aagctagaag caaccaataa actgagcaaa aacataaagc ggcaagcttt ggctttagga
     9061 acttcaaagc taagattccc aatactttta acatcacaaa agagagcacc aagctggtcc
     9121 tctctagata ttagttatta gtcaccccac tacagttgac attgagcctc tttgatgaca
     9181 ctagtcgtga attagtgaga caacaacata gcgattaggg tcgttgccct ctgaatagct
     9241 ctcaacccca tcaatagcag aaactgtttt atgaacaatc tttcgctcgc tgttactcat
     9301 aggatccatg gtataatctt gaccagactc aagcacacgc ttggatacct ttttggtaaa
     9361 gtcaatcagg gtttctgtcc gatgctctac ataatcatga acattcaagg agacagaaaa
     9421 attcttagaa tagcggtcat gtaagaaatt ttgggccagc aattgcagtg atttcaaaac
     9481 cttaccatga tagccaataa cacgacctgc ctctggtgtc tctatctgaa gattgatctg
     9541 acgacgattg ttggtcctct caatagaggc ttcaatatcc atctcataga taatcttggt
     9601 cacatagtca gaaatctcct gtgcagctag ctcaatatcc ttactcatgt ccgctgcagc
     9661 tggatccagc tgactcgcac cagcagctga cgacacaggc tgtgcctttg actgagtagg
     9721 agctgactga gctgtgctta atggacctgt tggctgatga gcatcagact cagcagccct
     9781 tctgtcttgt gatcgaacag ccttcatctc ctcaagctcc acctcatcgg ggttaataac
     9841 cggtgcattt tgacggttga tctcctctgg aacactacgt acggcttttt tatcagcctt
     9901 atagactgtt ttttcattaa tgccttcaat atcaacctga gctggctttt taccaaagcc
     9961 caaaaagccc tttttctcct ttgaaatcac cttgatgtgt gcttttagac gtgacaaccc
    10021 caactcttga agtccttttt caattgcttc ttcaacagtc ttacctgtaa acaataccat
    10081 atcctaaact cctattttct tttcattgct ctcttacgag cgcgacgttc cttagctcga
    10141 cgctcttttt cttcatctgc taaacgttgc ctttcggcaa taaccttaaa gggattatta
    10201 aacagcaaga gctgaacaac ctgaaaggca ttggaaactg cccaataaag caccacacca
    10261 ctggccagat taaagcccat aaagaagatg aacacaggca tcacgtaggt catgatcgtt
    10321 atcatggccg tcttttctct agccgctaga ttggttagcc atgttgataa aaaggtaaag
    10381 acagccgcta aaataggcag aataaagaga tgatcatgtc gcgccagctc aacccataaa
    10441 aaggtgcctt ctcttaagaa agccacacga gtcagagact gaaacaaggc aaacatcacc
    10501 ggcatctgaa tcagcaaggg caaaaggctc atgtaaggat tgacaccata ctttttgtac
    10561 agagcttgac tttcttcagc tagcttcata cgagttgctg tgtctttagc agcatatttt
    10621 ttttgcaggg cctttagctc tggttgaatg tcctgcattt tctgccctga cttgatttgc
    10681 atgttaaaca atggcagtaa aagcaagcga atcattatcg taaataggat aatcccaatc
    10741 ccagtcgatc catcaaagga caaccattgg atcgccttgg caaaaaaata aaccaattgc
    10801 tcccagctac tagatgattg tgctgtcacc tctccacgcc cacaggctac tagtagcaag
    10861 acaagcggca ctagggctgc tgttttaact ctttttttca atctcaaaac cttcctcaag
    10921 caattttgct agctttaaaa catgatgtaa attttgtttg actgcttgat aatctaattc
    10981 ctctgcacct ctcctagcaa taacaacgaa atcctcagac ttgaggtgat cacccagctc
    11041 cattaaaaca tgtcgtatct tgcgctttac cgcatttcga gtaacagcat ttcctagctt
    11101 tttgccaaca gaaatccctg ctcgaaaatg cttgtgctcc cctttcaaat ggtaaatgac
    11161 aaattttcga tttgccatgc tctgaccaag cttaaaaatc gcctggaaat ctttctctcg
    11221 cttgacacga tagcttttct tcaaaactta actcccatat ctaaattatt accattatac
    11281 cataaaacat taaaaagcct caacccttat caatgggcct ataataagag attggaccca
    11341 ctatctaaag gatcagaaca aaaaatgctt ttagtgaatc acggtagctg tcaagtcttg
    11401 atagccttat caatcatact agcaaagaaa caaaaaaata aagcccggta aaccgagctt
    11461 tatctccgct gacttgagca tcagcaaata tgatatccaa acaaagacaa ctgaaacaat
    11521 cattttaata acaagcagcc atatcaaaaa tactatttgt ttatggagag agagagaaaa
    11581 caatattttg attgaattgg ggatggacca ctccattacc taatgatttc gtaaatcttt
    11641 attcatacta gacattatag cgaaaaatca ctaaaaaaga tgacaatttc ctgaaatgtt
    11701 catttttcgt cctaaaatgt cattcaactt aatttttagc gaaaagactt ccacttttca
    11761 aaaagctgtt tcattctcaa acgagagacc atacaagaat caccattttc aaaatacacc
    11821 aattgcttag ccttatcaat tcgaacaaca ttgtcaagat tgaccaagta agaacggtgg
    11881 cataaaaaca gcttaggagc taccgcatga atctcagata agttcccata aaattctaag
    11941 cgctctgttt gcgtccacag gcacaccttg tgaggcgttg ttgcagttgc aaaataaaga
    12001 atgtccttat aaggcagctt taggcgggtc tgcggggtct caaacaaaaa catctcttct
    12061 acttgacgac tcgacatcat ctcataggtg tagcgaatac attcctcaat gcgctcttta
    12121 aattgctgac tatcaaccgc tttatcaata aaatccaagg cagacacctt gtacctaaag
    12181 gaaatagggg cgaactctga atgcgtcgtg acaaaaacaa gcacagcatt gggatccttc
    12241 tggcgaatat ctgaggctag ctctagccca cttcttgatt tgtcaccaat ttcaatatct
    12301 aaaaaataca gctgatgatc tcctctctcc tgaatgctat caaacagctt ttgaggattt
    12361 gaaaacacct ctaattgatt atgaggaatc ctaccctctt ctaatatgga cgccacaatg
    12421 gcctcaatac gactttgttg aatcagattg tcttccagaa taaaaatgtt tagcatggct
    12481 tatctcattt ctaacaattg tctcaaacgg tagtgatcac ttttggttga aaaggtgatg
    12541 tggggatagc gctctaacac agccgagaac tgtagcaggc gcttatgagc atggcttcct
    12601 agctccaatc ggctagcatc aaattgcttg gcaatatcaa cccgcttgag ccttgtacta
    12661 ttttcaatga taaaaaatcg cttgccatct tgattaaaat aggcaatgga taaaaaagga
    12721 cgagagctgc ctttagctga caaaatagca ttatcaataa ctaccttgaa aagaacgatg
    12781 acatctaaca gcctgacaga agagctagca agcgtttcag gaatatcgat gtaaacagca
    12841 atgccctgca gctttgcttc taatagcttg gcatgcaata ggctgcgaat caccgaatcc
    12901 tgaacattat caagggctga taattcaggt gttagctgcc tgatagagct tgctgattct
    12961 tggataactg tttgatagac cttagaaata gcagctatat ctccactatc aatactatcc
    13021 tttagactaa ttagaatatt ttctgaatca tgcttaatag ccctgatctc acgacaaagc
    13081 cgctcaatat actgattgtg cttttcaagg taagcaacac gctccttttg tgccagagcc
    13141 aatctttgag atagctgatc cttagcaaag cggtccagct tgacaatgac ccagatgagc
    13201 agcatgaggt aaagaaaaat catgacagag cggtaacgaa aataaatctt gaaaaaatct
    13261 ccttggatat tgatcatgca gtgaaccatc acatagtaga aaagtaaggc tgcattcatc
    13321 caaaagaccc acttctttag cttgtcctca ctgataaact taatcaaggt caaatcaacg
    13381 ctaaaaatat agctaaacag gtaaaaggcc ggcaaaacca atgcatgaca gaccatcaat
    13441 agacctatgt cattattgat ttgatgaatg ctgtagccta aaaccgctgg caaaaggaaa
    13501 gagccaataa tacgaaagag cagctcaaca atcataatcg caaacaagcc attaaacaga
    13561 tgctcagaag cctttttatg aggtgcaaag ccaacactga cagcaacaaa caccagctga
    13621 tcaactagca gcacatgatc cagcagcaga ttagcaacaa caaagcaggc accaaccaaa
    13681 agcaatgatc taacagctag cttaatgcct gaaaatgtcg aaaagatgac ccagctattc
    13741 acaaagatca gagcataaaa gaatgacata cctagcataa aataaaactc tactctttct
    13801 ctatttttgg catgattagg gtctgactaa actgataatc atgactcctg gtgcgcaagg
    13861 atagctcagg atatttctgc aaaatccgct tggcattaga caagcctatc cctcgaccgc
    13921 tcccctttga ggaatagccc tcttcaaaaa tcctactaat catgaccctt tcgtccttgg
    13981 tcgtattggt tacggtgaaa atctgctgat catcagataa aaagtaggct atcgccactg
    14041 ctggctgggc tgtctctaga gcagcctcaa tagcattgtc acaaaaaata gatacaagca
    14101 gcaataaatc aagctctgag atatagctat cccgaatccg atctggaact tctaggctta
    14161 aggcgattcc tgccttctca gccttaatga tttttgatga tagcaagctt tttatcgagg
    14221 atacactgat tttactgagc tttgaaatat tgtaatgctt atcgtcccaa taatccgtcg
    14281 cctcatctac cgtttgggca tagacagtct gtacatctga cacagagcca gagtcaatag
    14341 cctgccccag cctttctagc ctcttgaggt aaactagctg aaatacctta acacccttat
    14401 aaagcttttc tagatgcttt ccataggttt ccagattagc aatataagcc tgctgttcct
    14461 tttttaattc ctgttttaag aattcctttg attgatgatt aaaataagac agtaaataaa
    14521 tcaacaatag ggtaaagatg agaaacagca ccttataaga cgttgacatc attatcgggg
    14581 atttaaggtc aagaaaggga tcagtaaatc ctaaaatcat aaagagatca atatagtagg
    14641 ccaaactaaa gagcaaaaac aagctataaa agctactggc cttatcaaac ctgtcagctt
    14701 taacaatctg cttgtaatcc tttcccacaa aataattaat caaagcaaag cttgggaaaa
    14761 tcatcacata agcaataaag tctaggacaa ggtgtctgac atagctgcca ttaactgaaa
    14821 aaatataggg aagtacaatc gctaaaataa agcgtgataa caaatcaaca aacactccgg
    14881 gaacaaaggc caagaataga gcctttaagc taaagcaggg ccgcttttct aaggctaata
    14941 cagctagcag caataaagga tcaattatca agggcggcaa taaagcaaac tgattcaaaa
    15001 agagagctgc tgtcaggaca aaaatctgct tccaaagtgc cagtttaatg tctgataaaa
    15061 aggaaaaaat actaatttct gtcacataat aaatcatcag tgatagtaat aaaaagagat
    15121 aataaatatc agtcattctg cctccttacc aactttatta ttttaacaca ctttgtgtca
    15181 atccctatta tatgaatttt ttatataatt cagcaagcgc aaaaacagtc catagctggt
    15241 ttgtgacagc gtttgcaaat cagatgtcaa tcattaaagc aaattaaaat atctgaccag
    15301 ccttacctta tctagggaaa aatattgtat aacaaataat ctaagaaaac cagtgacaat
    15361 ttaatattta ttttaataat atcttccacg ctcatcaaaa attaagcaga taagcctgct
    15421 ggattatgac atctagctat gcgctactgg gcgtcgtgtc gctagctcaa gcacactaaa
    15481 aaagaatgaa gcaaacatca gatatctcat ctctgcttca ttcatgatgt tatttatgat
    15541 catcgtccag cctagaccaa actactagct gcgatagtgt ttaaagcata ttggcaatat
    15601 gctcaatcga ttgttcacgt ccaaggaggt aaatggtatt tggcagctct gggccatgca
    15661 tttctccaga aacagcaata cgaattggca taaagaggtt cttgccctta atgccggttt
    15721 ctttttggac agccttgatt tgtgggaaaa tgttttctgg cttaaagtcc tcatctgaca
    15781 tcgcctctag cttttccttg aaggccttca gaactgttgg aacagtctca gctgccatca
    15841 cttctttttc ttttgcggtc agctctggga aatctgagaa aaataaatca gtcaatggaa
    15901 caatctcatc agcagagctt aattgaggct gatagagctc aactagcttc tctgcttttt
    15961 cagtcaagcg gcctgctgct tcaagaaatg gcttacaaag cgcatataca gcgccaagat
    16021 cagcatgctt aaagtactca ttgctcatcc agtccatttt tttctgatca aaggctgctg
    16081 gcgacttgct aagacgaatc tcatcaaata aggcaatcaa ttgctcacga gaaaagatct
    16141 cagcctcccc gccaggattc cagcctaaaa gggcaataaa attaaagact gcctctggca
    16201 tatagccttt tttgcggtaa tcctcaataa actgcagggt attggtatca cgctttgata
    16261 gctttttacc tgtctcagaa ttaatgataa gggtcatatg accaaagacg ggtgcttccc
    16321 agccaagcgc ctcgtaaacc atcaactgct ttggcgtatt ggcaatatgg tcatctccgc
    16381 ggataacgtg tgagatttgc atatcgtgat catcaataac aacagcaaaa ttgtaggttg
    16441 gatagccgtc ttttttctgg attacccagt caccaccgac attgccaccc tcaaatacga
    16501 tatcgccttt taccatgtct gtccatttgt aaacaccagc ctcattgacc gctaaacgaa
    16561 ccgtaggcac aatacctgct gcttcacgct ctgcaatata ggccgccttt tcatatgctg
    16621 acatgccaag gtattcattg acatagcgag gtgtttcacc agctgcctct tgacgctcac
    16681 gctctgctgc cagctcctcc tcagtcacat aagacttgta agccttgcct tctgccaata
    16741 attggtcaat gtattgttga taaagggcta gacgctctga ctgacgataa cgctcgtgcg
    16801 tctcaggact ttcgtcccaa tctataccaa gccattttaa attttccagc tgagaacgct
    16861 cgccgtcctc gacatgacgc ttacgatcag tatcttcaat acgaataata aagtcaccgc
    16921 catgatgacg agcataaaga tagttaaaga gcgctgtccg cgcatttccg atatgtaaaa
    16981 ggcctgttgg gcttggtgca tagcgcacac gaattggttt agacattctt tttctcctat
    17041 ggtttcattg aaagaaggga tcctgggcta taaaccgttc ctacggtagg cttgctctat
    17101 gagaaaatgg tcgataagga acaaaaatac agctaatccc ttggaaatct aaagatttca
    17161 atcgctccta ttatagcaca acttcaagca ttgggcgaca aaaatcaact tagaacagct
    17221 gcataacgaa aatgcatgta accattttct agctacatgc attgttttca tctacttctg
    17281 atattttgat atcatcagct gttcacattc agcttaattg tagcctgaat tgatttgaaa
    17341 aagaccatac cactgatgag aaaatcgcta tcaaaaacgt aaagatcctt atgcgtttgg
    17401 cgtggcctag agctaggata gctctataag cagctcattg gcaagcagtg ctgcctcttt
    17461 caatagcttc atagcatgcc tagctataga tattagtcag gctattgacc tgcattgatg
    17521 tcaagctaca ccccagcaaa gaaagcgaca atatactctg gcaaccacga acctgtcata
    17581 tccatttcaa tccatcaatt ggcaaggctt ggtttacttc caactgctta atggccgcct
    17641 gtgacaatat agctctgtaa aactccagca aattgctgaa ggttcaggct ttgcacatag
    17701 acatctccgt atccgctaaa ggtattgacc actccctcac ctgtaccaat agactgcata
    17761 aagccatttt ccaaatgaat atcataatcc aaatcctgac tccaagccac cacatggcta
    17821 ttatcaatcg tcatgctgtc gccatgaagc gtgatttttt taatcgaacc aaaagcattg
    17881 accaataggg ttccttctcc ttgtgttgac atcacaaaga agccaccctg accgctaaat
    17941 aaggccttac caagtttttg gcgcttcatg gtgtagtgag ctgagccatc taaagccaag
    18001 aaggctccgt cattcaaacg gtattgatct acccctagct caagagcaat aacctgacca
    18061 ggcattgaag gggcaagcgc tagcttgcca ctaacatcat tagcaatcgc ctgtgtgata
    18121 aacatggatt ctcctgaaac cattgaacgg ccaatggcac caaccagctt gccaagacct
    18181 gagccacgcc cattgagctt ggtgtttaag ctgattgacg gtgtgtggta aaccatactg
    18241 cctttttgta gaaagacaga ctcccccatg tccaaatcaa tttcaacaag aggaaactgc
    18301 atgctgctgt caatagtata ggtcattcga ttataggcca taacaccact cctttgtatg
    18361 attttgttga tacaatcaag tatagtcttt tttggcagca ttgtccacta gctactgtcg
    18421 ccgccattcc taaccagtct caaagccata ctacaaaccg atcagctgtc aggatttcgg
    18481 catcgccacc tgagacatac gtccagtggc aacatcatag accgcaccac taatgaccac
    18541 gtcttttgga atcaacggtg attgctgcaa tatagccata tcctcacgaa cacttgcttc
    18601 cacatcagta aaggggagaa aatcacagtc agacacatct actcccagag tatcatgaag
    18661 ctgcgctgta aaggcttcat tggtaaaggt ttgcgcccca caatccgtat gatgaagaac
    18721 aacgatctca cgcgttccca gctgctgctg cgaaatcaca agagaccgaa gcatgtcatc
    18781 tgttatccgt ccaccagcat tgcgtaaaat atgggcatca ccaagcgcta aacccaaggc
    18841 ctgcgccaca tgcagtcttg agtccataca ggtcacaata gctaccttag ttttgggctt
    18901 taggggcaaa tgagcagtcc catgtaaggc gacataggct tcattggcag ataaaaagcg
    18961 ttcaaaatat gacatgaata cggtcctccc agactaatct ctaagctatc tcagccttga
    19021 gctgtctgtc tatcttatca tcttttgcct gaaatgtctg aatgctgaac tgctttttaa
    19081 cacaagcaga tagcactagc ctaactgaaa ccagaggtag gtgagccagc cttgacattg
    19141 gaagcaagct tagcagcccg ccctttgagc cgctaaagta agggcagcaa gaacgtgaca
    19201 aaatcagtta attgtcattt taattaaaaa acgaaactac ggagacaaac tgataaattg
    19261 ctatttctcg ctatcagcca gtatgctaaa ctcttctcag aaggccttgg cagtcgctag
    19321 ctgctaagcc aataatacta aattaaggag aatagcaatg aaacaaacaa aaataatctg
    19381 cttattggct gctgctgctg tcctaaccct aggtcctatc agcacaggcc agacacaacc
    19441 acagaccgta tatgccagtc aggttagtgg agacagctgt atcgatctag gtaatggatg
    19501 gtttaaatgt cctaaggata ttggaggatg ggacattctt tttaatcaag attaccaagc
    19561 gccttcacga tcgccatttt tcacttggat ttcaggctgg tttaacttta tatggcagtg
    19621 gtttaaaagc ttctaagatc tactaatacg ctatccatat cataaggctc ttagaggcta
    19681 gctctctaag ggctttttgg ttctacggaa cactataagg accttccaat actactggtc
    19741 ttaaaataaa aaagactagg aatagctccc ctagtcctca tgttaaaaac aacaacctaa
    19801 gtaaagacag cctttaagac ctctcctact gtcgtcacac caacaacctc aatccctttt
    19861 ggcagatcaa tcccctgcaa tgagcttttc ggagcgtaaa gcttggtaaa gccaagctta
    19921 gcggcttcat taatccgctg ctcaatacgg gtcacacgcc gaatatcacc agtcaagcca
    19981 atctctccta aaaaggcctc ctgagggttg gttggttttt ccttgtagct agaggcaatg
    20041 gccacagcaa ctgccaagtc aatagcaggc tcatctagct tcacaccgcc tgctgacttg
    20101 aggtaggcat cttgattttg tagcagcagc ccacatcgct tttccaagac agccataatc
    20161 agactgacgc gattaaagtc caacccagtt gtcgttcgtc tagcattacc aaaaacagtc
    20221 ggtgtcacca aggcctgcac ctcagctaaa atcggtctgc tcccctccat ggtgacaacc
    20281 acagcagagc ctgttgcgcc gtctaatcgt tcctctaaga acacctgact gggattgagg
    20341 acctccacta gcccacctga ttgcatgtca aaaataccaa tctcattggt tgagccaaaa
    20401 cgatttttaa ccgctcgcaa gatacgaaag gtatgatgcc tctcaccctc aaaataaagg
    20461 accgtatcaa ccatatgctc cagcatgcga ggccctgcta gggtgccctc cttggtgaca
    20521 tgtcctacaa taaaggttgc aatatgatta gacttagcta gctggagcag ctcagcagtg
    20581 acctctcgaa cctgactgac cgagccctga acacccgaaa tctccggact catgatcgtc
    20641 tgaatagaat caataatcaa aaaatccggc tgaatggctt caatctctgc tcgaatagcc
    20701 tgcatattgg tctccgcata gaggtaaaaa tcattgtcgg tctgtcccaa acgatcactg
    20761 cgcatcttga tctgctctgc cgattcctct ccagagacat ataaaacagt tcccttatcc
    20821 gcaagctgga tagaaacctg caagagcagc gttgacttac caataccagg atcaccacca
    20881 atcaaaacca agctccccgg cacaacacca ccgcccagca cacgattgaa ctcattcatc
    20941 tctgtctgga tacgctggta gcgaacgcca ttgatatgct ttagcttgat gggcttactt
    21001 ttttctccag tcaggctaat acgggcattt ttgacgtcct tgacctctgt ctcctctaca
    21061 aaggaagacc aggcagagca attagggcag cgccccagat atttgggtga ctgatagcca
    21121 cattctccac agataaacct cgcctttttc ttagctataa cacatttcct ccttgaatct
    21181 aagcatcaac tggctacaag cacgtgaagc agcctgctaa taccttatcc tcctgtcgaa
    21241 ccaaaaccac ctgtccgctc accaccagcc tgatcaccat cagcaatcaa aaaaggcata
    21301 aatacgccct gaacaatgcg ctcaccagct gacaaggtaa tggtttgatc cgtaatattt
    21361 ttcatctgag caaaaatatg cccttcattc gcagggttac catagtagtc accatcaata
    21421 acacccacag aattgatcag aaccagtccc tttttacgag gattgctgga gcgatcatag
    21481 agataaagca cctcaccgtc ttgcatatac gccttgaccc ctgttggcac aagtacaatc
    21541 tcacctggtg caatgctggt ctcctctgca acagataagt catagcctgc tgcatgagct
    21601 gtctcacgtt ttggtaataa atcagtatca gtaaagcctg acacaagctc aaagcctcga
    21661 atccttgtca tgattaacct caagagccct tgtcagtgcc tgcagcagct gtaaaatcac
    21721 ctgccaggac agcagacaaa agcactctta tcccttttct ttttttagtc ctcttattat
    21781 aaaatattcg taaaggaata gcaaaaaagt aggggctgca ccccaaaaat caccgactgc
    21841 ccccctctat aacgcaacaa aatgcaagag ggctaaatct ccttgccggc atagctaaac
    21901 cgaatccttg gaaaatcagc ctccaaatcc ttatctgcca taaaagcctt ggcgtccttt
    21961 ttcacctgaa ccagatcaat cccttgtatg tttgcagcat agacgcagcc gcaatagcac
    22021 tggcggtaaa tatcatattc ctcacacatt tcgaccgacc tgcgatagcc attatttttc
    22081 ttgaaatcac taggcaaata cttagtggtg taaacctttt gcacatcaat gcctacatcg
    22141 ttaatcgtct gtgagttttt atgagggctg atggtcaagg cactagcaaa ataatcaaag
    22201 cccagctcca cagccttttg tgccgtcttg tccaagcgat aatcaaagca aacacgacaa
    22261 cgatccccgc cctcagactc tttctccaag cctcggacag tcttgacaaa ttcatttggc
    22321 acataatctg cctcgataaa ctgcacgcta ttacctgttt tatcgttgaa ctctgctaca
    22381 aatttctgag taacataggc cctgcggtgg tattcgtcct ttgggtgaat atttgaatta
    22441 gcaaaataaa ccgtaatatc agcgtactgg gttaaatatt ccagcgtgta ggttgagcag
    22501 ggagcacagc aaacatgcat caaaatgcga ggacgtatag actccctcgc ccagaccttg
    22561 gtcatctgct gcatgacccg atcatagttt attttctggt ttggattcat tctagctaga
    22621 atctcttgta agtcaatcat tacatcttct accttctatt gtctgtctct tttattatag
    22681 cacattgcct tgacatgctt tgcatcaaaa aactccgcca aagcggagtc gatcggcaaa
    22741 agctgttttg atggttttta agaataacaa cagcagctta tgtaatgatc atttttagaa
    22801 gctactcaaa cacaaactga ttgtgataaa gctcggcata aaagcccttt tgccttagca
    22861 gctcatggtg acttccctgc tcaataacct taccgtcctt tagaacgatg atttcatcag
    22921 catttaaaat ggtttttagg cggtgggcaa tcacgaagct tgtgcgacct gccacgatag
    22981 cctccatagc cttttgaatc ttactttcag taacagtatc aacatttgat gttgcctcgt
    23041 ccaaaatcaa gacctgagga tcggttaaca gcgtacgagc aattgaaata agctgctttt
    23101 gaccagttga aaagacattc tcatcatctg acacctgagt ttggtagcca tcaggcaagg
    23161 acatgataaa ctcatgaata tgcgttgcac gcgctgctgt ctcaacctct ttttggctga
    23221 ttgtctgatt accaaagcgg atattatcag caatagtccc agaaaacaag actgactcct
    23281 gtaggacaat accaacccgc tgacgcagac tatccaagtc atattcccta atatcacgac
    23341 catcaaaggt aatagagcca gcatcaacat cataaaaacg attaatcaga ttcatgatcg
    23401 tggtcttgcc agaccctgtc ggtccaacaa cagcaaccat tttccccttt ggagctgaaa
    23461 tcgacacatc tgacagaatt ttttgtcccg gcagataacc aaagtcaaca tgcttaatct
    23521 caaccccttc ttttaatgct gtaaagacag gagcatgctc agggcgaacc tcttcttttt
    23581 catcgaacat ttcttggata cgaccagcac ctgtaaaggc cagctgcaat tcaccccagc
    23641 tagaggcaat ctgcataatc ggttgataat actgctgtga atactgaaca aaggtcacca
    23701 ccaagccaag agcagcagct gttgacatgg acttgtcacc aaggacaatg gttgagccag
    23761 caaagatgac aatagctgta ttcaaaagac tcatcccatt catcacagga aacagcagac
    23821 cagcaaaaag gcgtccctta aaggttgctg cacgcaccct ctcattgtgc tcaataaagc
    23881 catcaatagc atcctgttgc accccttgaa caataatagc cttctggcca gaaatcttct
    23941 cgtccatgta agcatttaaa gcactgacct ccttttgctg caaatcagta tatttgcggg
    24001 ccattgtaat gatgacaacg agaagaataa gcgccacagg ggttgaggct atcgttacca
    24061 aggccaagcg actatcctgc ctaaacatca tcagcactag accaatatac aaagcaatat
    24121 ttgtcaagac ctgaatcaga gattggttca tggagttttg aatattatca agatcactgg
    24181 taaagcgtga tagaatagca ccgtccttgt gactatcaaa aaagccaact gtcaagcgct
    24241 ccaatttgcc aaataagccc ttacgcatgc gattggtcga atgcgaaata acccttgtaa
    24301 agaggagact ataaataaga ttagccactg ctgtaaagag ataagccaac aatagctttc
    24361 ccataaccgt cctaaaaggc gccatagagg gctcaactaa gggctgaccc gtcattttgc
    24421 taagcgcctg agccttgtaa tagcgctgca cccattctcc cagctcagct agagagtctc
    24481 ccaaaaagac aggggcctta acctgcaggt aggttgccag gacaatagca aagaatatca
    24541 caacaaaaga gagcttataa cgtttaaaat aaaaccagaa aaatcgcagg atcttcatta
    24601 gttctcctct cttccctttt gagtttcgta aatttcacga taaatcggat tggaagcaac
    24661 cagctcagca tgcgtccctt ctccaatcaa tcgaccatta tcaagaacaa gaatcttatc
    24721 tgccttgaca actgacgata ttttttgtgc gatgatgact gttgttgtct ctttgagctc
    24781 cttattcaag gcctcctgaa caagcttttc agatttggca tctagagctg atgtcgaatc
    24841 atcaagcacc aaaatcttag gattgttaat cacaccacga gcaattgaca ttctctgctt
    24901 ttgaccgcca gaaaaattat tgccacgctc ttctacctca ctctggtagc cagcgtccat
    24961 acggtcgata aattccttgg cctgcgcaat gcgtgctgca ttttctaaag ccaattggtc
    25021 agcataggga ttgccctgac gcagattatc cgcaatagtc ccagaaaaaa gaatagcctt
    25081 ttgcagcaca atagagacgg tgtcgcgcag agtctcttga ctgatgcttg gcagagcctt
    25141 accaccaatc aggatttgcc cttcctgtgg gtcaaacaaa cgcggaatca gctgcgcaag
    25201 ggtcgacttg ccagcacctg tcgcaccgac aataccaacc atttgaccgg gctcaacctc
    25261 aaacgaaata tgctttagag tggcttcact gtcatttgga taggtaaagc tcacatcatc
    25321 aaagacaata ctgcctgtca gctcctcctg ctcatggtta acaaaggtca tagcaggctc
    25381 tgtttctaaa atctccctga tccgaccaat cgaggtcaag gcacgacttg cctgcattcc
    25441 cataaaacca accatcgtga tcgcaaagct gatttgtccc atataggtca taaaggaagc
    25501 catatttcca ataacagcag gatctgtttt gaccagccct gaaaccagat acaaggacaa
    25561 ataaatggcc atgtaagaca ccaacatcaa aataggctgc atgattgaaa agccatagcc
    25621 gataaacaaa ttcaagccca gtaggtcatt tgaagcctcc ttaaatgtgt catactggct
    25681 tttttcctga acaaaggact tgaccacacg cacaccgcgt aggttttcct tagcaatctg
    25741 attgatccta tccatcaagc gctggaagat cccaaagcga ggacccatct ggctcatcac
    25801 cagcccaatg actaccattg tcatcacaac cacaagcacc aagacccacc aaaggctcgg
    25861 taaggcctgc accgctaaaa taaaggcacc gacaaataaa atcggcaagc gcaacaatat
    25921 ctgaaaaagc atcatcacaa agttttggat ttgattaata tcatttgtca ttctaacgac
    25981 aagatttcca gcattgaagg cttccacatt ggcataagaa aaggattgga tctttctaaa
    26041 ggtctgctca cgaatatcag cagatacccc ttgagcaatc ttggcagaca agatggtatt
    26101 gaccgcacct gacaccaagc caatccctgc tatcactaac agccaaaaac ccacctctgc
    26161 aatccttgtc tgatcatttt ccataatagc agctagaaca tctttgaggt aatgtggctg
    26221 gagcagggca ctggctacga ccccagaaat catcactagg gacagagccg cataccattt
    26281 atacttcatc acagcatttc taagcatctg tatctccttt ataagctcgt atattttgtt
    26341 tcagctgatc gataaccttt tttaccgtca gcagctcttc tcttgaaatt tccttgaaaa
    26401 aatagcgctc aatatctctg cggcactcct ttaataccgg cagcttagcc ctaccagccg
    26461 aggtcaagac aacctgcttg cagcgcttat ctgtagccga ggcaacaact cgaataaagc
    26521 catttttttc catacgcttc accagattac tcgtaaccga ttttgagatt tgaagctcct
    26581 tttcaatgtc cttgacaaaa atgtctctgt cttgatggca atgcaaaaag acaagaacat
    26641 gcccttgtgg accagcaaga tgctggaggt catacttttt agcaatctct tcgctaattt
    26701 gctcaacctg atgggtcaat tcacgaagct cagcaatgat tcttggcatt tccttcctcc
    26761 ttagttctca tgataaccat tttagttctc ttgggaacta ttgtcaacca aaaaggctta
    26821 cgatctgact atcttccctg ctacttaccc tttgctagca ccactgagct gacaggctag
    26881 gccagcagac cttttctatt agagttaggc cttgtcttat gatataataa ggtgattagc
    26941 tcttaaagga gaataaaaat gccaaaacaa aaggtagcca ttttgggacc tggctcttgg
    27001 ggcacagccc tggcacaggt cctaaatgac aacggacatg aggtccgact atggggaaat
    27061 atccctgaac aaatcaacga aatcaacaca cgccatacta atagtcatta ttttaaggac
    27121 attgtcctag atgaagccat caaggcaacc cttgatttga aggaagcatt ggctgatatt
    27181 gatgctatat tgtttgttgt gcctaccaag gtgactcggc ttgttgccaa gcaggtcgct
    27241 caggtcctag accacaaggc tattgtcatg cacgcctcaa agggattaga gcctggaacc
    27301 catgagcgcc tctcaacgat cctcgaagag gagatccctg cccagctgcg cagtgaggtc
    27361 gtggttgtgt ctgggcctag ccatgccgag gagaccatcg ttcgtgacat taccctaatc
    27421 actgcagcct caaaggacat cacagctgct aggtatgttc agaccctctt tagcaaccac
    27481 tacttccgtc tctacaccaa tactgatgtg atcggtgttg aaaccgctgg cgctctcaag
    27541 aacatcattg ctgttggagc cggtgctctg catggccttg gctatggtga caatgccaag
    27601 gctgctgtca tcacacgcgg tcttgcggaa atcacacgac taggggtcaa gcttggggca
    27661 gaccctctga cctatagcgg cctatctggt gttggtgatt tgattgtcac aggaacatct
    27721 gtgcattcac gcaactggcg agctggtgct gctcttggtc gcggcgaaaa gctcaaggac
    27781 atcgaaaaca atatgggcat ggtgattgaa ggcatttcca caaccaaggt agcctacgaa
    27841 attgcccaag agctaggggt ttatatgcca attaccagcg cgatttacaa atctatctat
    27901 gaaggtgctg acattaaaga aagcattctg ggcatgatgt caaatgaatt tcgctcagaa
    27961 aatgaatggc acacataagg aaccacaaat caaggaggaa ctcatgacaa aggtcagaaa
    28021 agccattatc cca
//
LOCUS       DARYXS010000016        27160 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.016, whole genome shotgun sequence.
ACCESSION   DARYXS010000016 DARYXS010000000
VERSION     DARYXS010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27160
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.016"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            77..352
                     /locus_tag="TV193_000567"
     CDS             77..352
                     /locus_tag="TV193_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEL1512793.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFASPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDIALKEMENWV"
     gene            349..1671
                     /locus_tag="TV193_000568"
     CDS             349..1671
                     /locus_tag="TV193_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1512794.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWSTEIGKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGARLETSQTRFKDKYFVPDKRNGLIIYSWALRDGAEAEIYNKIE
                     DICISMKAKDYLKLPPRTDNVVSVKLSNMKAYKQLEADLVLEFKDKEISAANSAVLAN
                     KLLQMANGAIYDDDKTTVAIHDDKLDALENVVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGKIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            1672..1860
                     /locus_tag="TV193_000569"
     CDS             1672..1860
                     /locus_tag="TV193_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512795.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLRFWDSCEAT
                     VKEKYTREREMKNEQTKI"
     gene            1841..2068
                     /locus_tag="TV193_000570"
     CDS             1841..2068
                     /locus_tag="TV193_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512796.1"
                     /translation="MNKQKFEKLDKVKELLDELKMSEFMAPLLVGDQIMEIINDLHND
                     PGQFGAQVFLPSPDKKYKFVVRICREENLED"
     gene            2093..2278
                     /locus_tag="TV193_000571"
     CDS             2093..2278
                     /locus_tag="TV193_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512797.1"
                     /translation="MAENKTGMMTLPIDYANRALAKEEILDELVEREIVDVDLLIELA
                     EDNPFWMSALNFNRGTK"
     gene            2275..2568
                     /locus_tag="TV193_000572"
     CDS             2275..2568
                     /locus_tag="TV193_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512798.1"
                     /translation="MNTNEKVIDTICHIRHCGDRYDMCQDMRSWVAERNGLIQDLLKA
                     KKQIDRNRIAKRLDRAQKNISDIITKVTGDLWQGSDQVIAEQCFLKVLEEMQK"
     gene            2565..3281
                     /locus_tag="TV193_000573"
     CDS             2565..3281
                     /locus_tag="TV193_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1512799.1"
                     /translation="MNIKEAKIGDKVWVEGIINSSFSNGGVHVNHAGVDAFYDLERTK
                     IKPDGYAGQSPKYLKNIIAKMRELPEHDRAVWIKGIFKEFGIENDISYYLGHKQGVLQ
                     AKDSLKPEVLQYVADWYEKHKDNLEYYIWEYIAEWDNQEKDDFFVFMNFSAFKPIQTL
                     VNMHQFGYTIKKEKLYTVEIPNPNAKQIALRLEKWVEGKVRIVATYSSNNFTDYMRLT
                     EREIRKDFDWAWQFAEEVTG"
     gene            3278..3694
                     /locus_tag="TV193_000574"
     CDS             3278..3694
                     /locus_tag="TV193_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEL1512800.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            3784..4236
                     /locus_tag="TV193_000575"
     CDS             3784..4236
                     /locus_tag="TV193_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1512801.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            4226..5503
                     /locus_tag="TV193_000576"
     CDS             4226..5503
                     /locus_tag="TV193_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1512802.1"
                     /translation="MTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGAEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAN
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLPSFFGLDYGFINDPSALLHV
                     KIDDANKKLYILEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWIVDERCVKTIEELENYTWKKDKKTNEYTNEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            5519..7051
                     /locus_tag="TV193_000577"
     CDS             5519..7051
                     /locus_tag="TV193_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1512803.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEKIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKAYTSDTIYTYEDYN
                     LETKGMRLKDYEGHFFRGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            7011..8459
                     /locus_tag="TV193_000578"
     CDS             7011..8459
                     /locus_tag="TV193_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL1512804.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQKDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKVASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKRLKQGFVRGEHPRAMARDLAKR
                     FNVANHRAETLIRTDGTMVINNATARRYLNAGLKYYRDLVRLDDRTTEICRTIAKENK
                     RKLLSELKPGINVAPYHFNCRTTIIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNE
                     HKPQLSLLNEYVKNGTPYKVDGHSVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HIKTPDYLVDGAPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEHIYMIDRRGLDISIIKNKDEVLAVLEKEGG"
     gene            8487..8675
                     /locus_tag="TV193_000579"
     CDS             8487..8675
                     /locus_tag="TV193_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512805.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKEG"
     gene            8680..8937
                     /locus_tag="TV193_000580"
     CDS             8680..8937
                     /locus_tag="TV193_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512806.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKQIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRK"
     gene            9114..9683
                     /locus_tag="TV193_000581"
     CDS             9114..9683
                     /locus_tag="TV193_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1512807.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKHEYERTFTRADISKMMAAE
                     RTKWESEQSAAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            9696..10583
                     /locus_tag="TV193_000582"
     CDS             9696..10583
                     /locus_tag="TV193_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1512808.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            10595..10951
                     /locus_tag="TV193_000583"
     CDS             10595..10951
                     /locus_tag="TV193_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1512809.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAIYESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGAVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            10962..11240
                     /locus_tag="TV193_000584"
     CDS             10962..11240
                     /locus_tag="TV193_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512810.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKSRLIKGLAHHKNSTVIYV"
     gene            11237..11581
                     /locus_tag="TV193_000585"
     CDS             11237..11581
                     /locus_tag="TV193_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1512811.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYSEQQRLLHYRVVSPALYSIYLELGTRKMEAQSFLDPALRKEWP
                     VLMANIKKMFKR"
     gene            11585..11944
                     /locus_tag="TV193_000586"
     CDS             11585..11944
                     /locus_tag="TV193_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512812.1"
                     /translation="MDYSLETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKSRMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            11956..12555
                     /locus_tag="TV193_000587"
     CDS             11956..12555
                     /locus_tag="TV193_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL1512813.1"
                     /translation="MANTKKGTTIEITTGKPIVGKKIFYFIQSVDAPKKSQALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESTGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            12609..13064
                     /locus_tag="TV193_000588"
     CDS             12609..13064
                     /locus_tag="TV193_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512814.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDMDATQIQIIEDMIGRMSNAVS"
     gene            13139..13372
                     /locus_tag="TV193_000589"
     CDS             13139..13372
                     /locus_tag="TV193_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512815.1"
                     /translation="MEGLEYKQLAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            13387..17769
                     /locus_tag="TV193_000590"
     CDS             13387..17769
                     /locus_tag="TV193_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1512816.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNTFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFQKIIIPVASVIDKIRGNLTGFINQTKMQLQNLVGIGKIRSAFAKAATGVDILTQR
                     ASSKLNNLSAIFETVAGKLPRPFGTAFRKIASSVSTLNSSIQSVGGKISNSLGQQVLN
                     PALQSWNNFFSSVSAKASAFANKVSTSLFGRLTSSLANLSSKIGSSLSNGFSRMSSSA
                     ATSLNGISQKFANTSSAGERLKSTVMSIVQAFSLMAVAQKAMHAITGAIDGAVSRVDT
                     MNRFPKTMALFGYSAEQSKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTS
                     LALAFNNAMIGYGATTEGAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAF
                     GFGKNGVQDLKSVLSDGKITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHT
                     AVVKGVAGMISAFDEAAKANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLK
                     QSINIDFSPLGASVKEVFALINIVFGDFAHTGELSEQAFDNLKAKITSLAPKVIALWA
                     VMNPASAISTIMPLLSLFGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLS
                     GLPGVFATAAGRGLSVLGTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQ
                     IEQLLNTAVTKGPGIIQGLVKGITSKIPVLIASGTQLIAKFANAIAVLLPVIIQAGVQ
                     LITSLVQGIGQNATNLISSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIP
                     LIIQQAQQIIDSFGNSLQANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFV
                     SGIVQFLPQLLQGGIQIIISLVQGIIQNLPQIAQSAVQIIQSLASGLTQALPQIIAAG
                     IQLVAQLAVALIKGLPQIISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQ
                     ITGKSSTSTAKVSADATVMAMNVGMQTTAMANQANTDTTSMLNSISQNTELANINATS
                     NATQMANNVNAQTGTMSLQGLNDSMSLASGISTNMSVANINATTQAREMASGVNGATS
                     SMNLDAINHTLSLASGVGANMGAASTGATSQAQAMSSGVSNSLASMQSNSTKAASGLS
                     NSVTSEMSSAATSATSSVNRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTA
                     KQSMANLVSSVTSGMSRATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASS
                     AGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLG
                     KAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVG
                     DKIYTAVKEKESREQSKDSYFVFD"
     gene            17781..18623
                     /locus_tag="TV193_000591"
     CDS             17781..18623
                     /locus_tag="TV193_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1512817.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGETKPKDITLSGGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            18633..20615
                     /locus_tag="TV193_000592"
     CDS             18633..20615
                     /locus_tag="TV193_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1512818.1"
                     /translation="MITFLDHRDIEYGVISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAAL
                     KNLALPEEAIKKITEAIKVDDIPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRY
                     NKNLLVGEPNRVKKIDEDFIEVEANDGGFKRGETYTISFSQTCEPLKKVAITLIQANN
                     KGVKLVLTPTKAKMEPETFTLIKDTEVINVYPLSYSVTLSGDWYKSKQVDLNASEVRN
                     MALGMSYRDVVDGNNADLILDWAENPDIIFDGNGGI"
     gene            20615..21733
                     /locus_tag="TV193_000593"
     CDS             20615..21733
                     /locus_tag="TV193_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1512819.1"
                     /translation="MSKEVASARIQHRGMTKQEWESSSDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPSGERGLTGPIGPRGPAGKPGTTDYNQLQNKPNLDAFA
                     QKKETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKP
                     SSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNA
                     VNIVMRQPTTPNFSSALNITSDNENGSAMQLRGSEKALGTLKITHENPNVEAKYDENA
                     TALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKET
                     SQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
     gene            21748..23634
                     /locus_tag="TV193_000594"
     CDS             21748..23634
                     /locus_tag="TV193_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1512820.1"
                     /translation="MSRDPTLILDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRKLS
                     ASYQAGIEGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGTRTELESQISGLRAVQQSTASQISQEIRDREGAVSRVQQSL
                     ESYQRRMQDAEENYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFS
                     INRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVTNELNNH
                     INKI"
     gene            23646..24083
                     /locus_tag="TV193_000595"
     CDS             23646..24083
                     /locus_tag="TV193_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1512821.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            24080..24691
                     /locus_tag="TV193_000596"
     CDS             24080..24691
                     /locus_tag="TV193_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1512822.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQGLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD"
     gene            24703..24975
                     /locus_tag="TV193_000597"
     CDS             24703..24975
                     /locus_tag="TV193_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512823.1"
                     /translation="MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA"
     gene            24972..25199
                     /locus_tag="TV193_000598"
     CDS             24972..25199
                     /locus_tag="TV193_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEL1512824.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            25316..26650
                     /locus_tag="TV193_000599"
     CDS             25316..26650
                     /locus_tag="TV193_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEL1512825.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLSTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
     gene            26924..>27160
                     /gene="spei"
                     /locus_tag="TV193_000600"
     CDS             26924..>27160
                     /gene="spei"
                     /locus_tag="TV193_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047373492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeI"
                     /protein_id="HEL1512826.1"
                     /translation="MSSVGVINLRNLYSTYDPTEVKGKINEGPPFSGSLFYKNIPYGN
                     SSIELKVELNSVEKAKFFSGKRVDIFTLEYSPPCN"
BASE COUNT         9108 a         4717 c         6053 g         7282 t
ORIGIN      
        1 aaacacatat ataaaaaaag agaaaataag ttgaaaaaaa cggtaaccct gacctttatt
       61 gaccaaagga ggaaagatga ggactgaaaa agacattgaa aattatttga aaaagaaaac
      121 aaaagggctg tgtttaaaat ttgcaagtcc agggacgata ggagtgcctg acagaattgt
      181 tgtcatgaac acgggaacct tttttgtaga ggtcaaagca cctggtaaaa aaccaagacc
      241 cagccaagtt gccatgcaca aaaaaataaa agaggctggg cagcacgttt gggttgttga
      301 ctcctacgaa tcagtggaca tagccttaaa agaaatggag aactgggtgt gagactgcac
      361 gagtaccaag aatacgctaa gacatggata gtagagcacc cttattgtgg ccttttactt
      421 gacatgggtc ttggtaaaac gctgacaaca ctatcggcaa tagatgagat tcaaaatatt
      481 ttttccgagg atcataagat tttaatcgta gcccctaaaa aagtggcgga agaaacgtgg
      541 tcaacggaga ttgggaaatg gcattttgat ttcacctact ctaaagtttt agggagtgag
      601 ggaaaacgaa ttgaagcctt agaaacagaa gccgatatct atttgattaa tcgtgagaat
      661 gttacttggc ttgttgaata ctacaagact aaatggccgt ttacctttgt ggttattgat
      721 gagctgtcaa gctttaagtc tagtaagtca aaacggttta gggctttgcg aaaagttaga
      781 ccgaaagtcc aacgccttgt aggactaaca ggaaccccag cgcctaacag tttgattgat
      841 ttgtggccgc agatttatct gatggacaga ggcgccaggc ttgagacgag ccagactcga
      901 tttaaagaca agtattttgt tcctgataag cgtaatggcc taatcattta cagttgggca
      961 cttagggatg gtgcagaagc agaaatctat aacaagattg aggacatctg tatcagcatg
     1021 aaagctaaag actatctcaa gttaccgccg cgaaccgaca acgttgtatc agttaagtta
     1081 tctaatatga aagcctacaa acagcttgaa gctgatttgg tgttggagtt taaggataag
     1141 gagatatctg cggctaactc tgcggttttg gctaataaat tacttcaaat ggctaatggc
     1201 gctatctatg atgatgataa aacaacagtt gctatacacg acgacaaact tgacgcgctt
     1261 gagaatgtcg ttgaagaaag ccaaggccag ccaatcttag ttttttacca gtatcaacat
     1321 gatcttgaaa ggcttaagaa acgattccct caggctgaag agttgacgtc agttgacaag
     1381 tggaattccg gaaaaatacc aattcttctg tgtcacccac agtcagccgg gcatgggctt
     1441 aatctgcaaa aaggagggca tattattgtt tggtttgggc taacatggag tcttgaatat
     1501 tatcaacaag ctaatgccag attagacaga caagggcaga cagaacccgt tattgtgcac
     1561 cacattgttg cagaaaatac agttgatgaa aaagtactta ggattttaca aggcaaagaa
     1621 aaaaatcaga acgccttact tgaagcagtt aaggcgcagt taggggtcta gatgaaaaaa
     1681 gaatatgtcg ttagaatcta cacgggtaga gaaaagaatt ttgaggcaaa acctcagttt
     1741 gaagagaaaa cctttacgcg aaaagcagac atgctgaggt tttgggattc ttgcgaagca
     1801 acagttaaag aaaaatatac tagggagcgg gagatgaaaa atgaacaaac aaaaatttga
     1861 aaaattagac aaagtaaaag aactacttga cgaattgaaa atgtcagaat ttatggcgcc
     1921 acttttagtt ggtgatcaga ttatggaaat tatcaacgat ttgcacaatg atccaggaca
     1981 atttggagcg caggtatttc tgccatcgcc agacaaaaaa tataagtttg tagtgcgaat
     2041 ttgtcgagaa gaaaatttag aggattgagt taacgaaaat gagggtagga taatggctga
     2101 aaataaaact ggaatgatga ctttaccaat cgactatgca aacagagcat tagcaaaaga
     2161 ggaaatactt gatgaacttg ttgaaagaga aattgtagat gtagatctgt taatagagct
     2221 tgcagaagat aatccgtttt ggatgagtgc attgaatttt aaccgaggta caaaatgaac
     2281 actaacgaaa aagtaatcga tactatatgt cacatcagac attgcggtga cagatacgat
     2341 atgtgccaag acatgcggtc gtgggtagct gagagaaatg gattaatcca ggacttactc
     2401 aaagcaaaaa aacaaattga tcgcaatcgt atcgctaaac gtctggatcg tgcgcagaaa
     2461 aacatcagtg acattatcac aaaagtgaca ggcgacttat ggcaaggcag tgatcaagtc
     2521 attgctgagc agtgtttttt aaaagtatta gaggagatgc aaaaatgaac attaaagaag
     2581 cgaaaatagg cgataaagtg tgggttgaag gtattatcaa ttcgtccttt tcaaatggtg
     2641 gagtacatgt aaatcatgct ggtgttgacg ccttttatga tcttgagcga acaaaaataa
     2701 aaccagacgg atacgcaggg cagtcaccta aatatcttaa aaatattatt gctaaaatgc
     2761 gagaactacc agagcacgac agagccgtct ggattaaagg tatttttaag gaatttggta
     2821 ttgagaacga cattagctat tatcttggcc acaagcaagg cgtattacaa gcaaaggatt
     2881 cgctaaaacc agaagtactg cagtatgtgg cggattggta tgagaaacat aaagataatt
     2941 tggaatatta catttgggaa tatatagccg aatgggacaa tcaagaaaaa gatgattttt
     3001 tcgtttttat gaattttagc gcatttaagc ctatccagac gttagttaac atgcatcaat
     3061 tcggatacac aatcaaaaaa gaaaagctgt atacggtgga gatacctaat ccgaatgcta
     3121 agcaaatagc tttgagactt gaaaaatggg ttgaaggaaa agtaagaatt gttgcaactt
     3181 actcatctaa taattttaca gattacatgc gcttaacgga acgagaaatc cgaaaagatt
     3241 ttgattgggc gtggcagttt gcggaagagg taacgggatg agtagattat ctaatgcaca
     3301 gctaaaggct tttgatgaat ggttgtttga ttatcgtttt attgataaca agattgcact
     3361 tcgaaaactt gagctacaaa ctgacatgaa tacagaagta gataaaaata tcggtggagg
     3421 aagagcaaat tttgtttcaa aagttactga ggatgtggtt gcaaggtggg attcagatag
     3481 ggaactaaag ggtctatcca atttcaaaga agcagttatt gcaacgctaa atcttttgga
     3541 tgaagaacta actgatattt ttaatcttag gtggggcgtc ggttcaagta acacttggga
     3601 agaaattgcc tatacaagac atctgtcgcg taagtctatt taccgcaaaa gagagcggat
     3661 tctagaaata ttttccaaaa aaataggaat gtgacacaaa aatgtatgga attgtcatct
     3721 ttttgatgat aaattggtag tatgagtttg aaggtaaggc agatagtgtc ttgccttttt
     3781 gctatgcttg gaggtgatgg aaaattgagt aaattaaccc taaaacagaa gcgttttgca
     3841 gatgagtaca tcatctcagc taacgcgaca gcagcggcta ttaaagcagg gtatagtaaa
     3901 aagacagcaa ggtcaatagg tcaagaaaac ttgaccaaac ctgacattaa agcttatata
     3961 gacgagcggc ttgaaaaact tgaatctgaa aagattgcta cgcaagaaga agtcctacaa
     4021 tatctcactt caattatgcg aggagaccaa caagaaaaga cgctcattag cgttggagag
     4081 tttggtcaga agatagttga catcgatgtt ggtgccaagg atagaatcaa ggcagctgag
     4141 ctactaggca aacggtacag gttatttact gacaaggttg aaatggatgt cagctcagat
     4201 gtaaccatta acgtaggtga gtgggatgac gactaaacag cgccctaaaa ttaatatcgt
     4261 gatcaagcat cctagcaaag tttttaacaa acatatctac gacaaacttt acaactatag
     4321 caacttcacg gaagttcatt atggtggggc gtctagcgga aagtctcacg gtgtttttca
     4381 aaagataatt ttaaaagcac ttaaccctaa attcaaacat cccagaaaga tattagttct
     4441 cagaaaagtc ggtgcaactg ttagagactc tgtatttgct gatatcatgt ctaatttgtc
     4501 gtatttcggc atcttggata aatgtaagat aaatatgtcg gcttttagaa taacgctccc
     4561 aaatggcgca gaattcattt tcaagggtat ggacaaccca gagaagatta agtcaattaa
     4621 gggtatatct gatgtggtta tggaagaagc tagtgagttt acgcttgatg attatacgca
     4681 gttgaccttg cgtttaagag ataagaaaca tctagagaag caaatatact tgatgtttaa
     4741 cccggtatca aaagtaaact gggtttataa agccttcttc gttaagacac ctaagaatac
     4801 agttgtctat caaacaactt ataaagacaa ccgcttctta gatgatgtca cgagagaaaa
     4861 tatcgaggaa ctagccaata ggaatgaagc ttattacaaa atatatgctc ttggccagtt
     4921 tgctacactt gataaactaa tttttcccaa atatgacaag caaatattaa acaaagacaa
     4981 gttatcacac ttgccttctt tttttggttt ggactatgga tttatcaatg atccttcggc
     5041 acttttgcat gttaaaatcg atgacgcaaa caagaagtta tacatcttag aggaatatgt
     5101 caggaagaat ttgaccaatg acaaaatagc aaatgctata aaggacctcg gctacgccaa
     5161 agaagaaatc agaggagatt cggctgaaaa gaaatctaat caagagctga ggaatttagg
     5221 tattcctaga atgattgatg ttaccaaagg gcctggaacc gttatgcaag gaatacagta
     5281 tttgcttcaa tatgattgga ttgttgatga aaggtgtgtc aagactattg aagaactcga
     5341 aaattacact tggaagaaag acaagaagac taatgagtat accaacgaac cagttgacag
     5401 ctataaccac tgcattgatg ccataagata tgccgtacaa gacagaatat accagtcggc
     5461 ggatagaagt aagcgcatga aaaatgctaa atattatttt taggaatgag gtgaaacttt
     5521 ggaagaaaaa caatttttag caggaactcg ttttaatgag aatgctaata agcaatttat
     5581 tatgctgcaa gaagactttg aagcaattga ctatgaatca aaactttgga tagatcaact
     5641 taagaattac atttcaaggt ttaaagcaga acaattagag cgtttgaaag agttaaagcg
     5701 atactatctt ggggataata acatcaagta tagacctgct aaaacagata aatacgcagc
     5761 ggataatcgt attgcaagtg attttgctaa gtatattacg gtatttgagc aaggttatat
     5821 gcttggcgtt cccgttgagt acaaaaatga aaataaagac ctccaggcag ctattgacct
     5881 tatgtcggtc agaaacaatg aggactacca caacgtcaaa ataaaaacag atttatcaat
     5941 ttatggaaga gcctacgagc tgttaactgt tgagaaaata gatgacaaaa aaaccgaagt
     6001 aaaactctac cagctcccgg ccgagcaaac ttttgttatc tatgatgata cataccagcg
     6061 aaattcgttg atggccgttc atttctacga catagattac ggctcaggta aacgtaaaca
     6121 gattatcaaa gcatatactt ccgacacaat ttatacctac gaagactata accttgaaac
     6181 aaaaggtatg cgattaaaag attatgaagg acattttttt agaggtgtac cagtcaacga
     6241 atacgctaat aacgaggagc gaacgggggc ttatgagtct gtacttgata atattgacgc
     6301 ctatgattta tctcaatcag agcttgctaa ctttcaacaa gattcagtca atgcgttgct
     6361 tgtaatagct ggtaatgctt acacaggagc tgatgagaat gactacttag atgatggccg
     6421 attaaatcct aatggtcgtt tagcgatctc aattgggttt aaaaaagccc aagtgttaat
     6481 tttagacgat aatcctaatc caaatggcgt taaaccgcaa gcgtactttc tcaaaaaaga
     6541 gtatgatacc gccggtagcg aagcctacaa aaatagatta gttgcagaca ttttgaggtt
     6601 tacttttacg ccagatacac aagatatgaa attttcagga gttcaatctg gtgaatcaat
     6661 gaagtataag cttatggctt ctgacaacta tcgcgagaag caagagaggt tgtttaaaaa
     6721 aggattaatg cgacgcttac gcttagcagc taatatctgg gccatcaaag ggaatgaagc
     6781 aactacatat agccttgtaa atgatacgag tatagttttc acacctaatc ttcctcaaaa
     6841 cgataatgaa attgttacag ctgcacaaaa tctttatggc attgttagcg atcagactat
     6901 ctttgaaatc ttaaatactg tcacaggagt agatgctgaa gcagagcttg aacgcttgaa
     6961 agaagaagct gataaaaagc aatctttacc ggagcctaga ttggtaggtg atgctagtgg
     7021 tcaagaagaa ccaacggcag aaaagcctta attactggca aaagcgtcaa aaagatattc
     7081 taagttattt agacagaact gatttagatg tcttttcaga actgcagaag ttatataatg
     7141 aacaggcttt tgagttacaa aaggaattgt ttgattttta tactaagtat tctgaagaga
     7201 acaaaatgac ttatcaggat gtcgttaaaa aactacgtca tgaagattta tcagattacg
     7261 tagctaatgc taacaagtat cgtaaacaag ctgagaaaga tcctgagctg ctaaaacgac
     7321 ttaatgagca gtatgtatca gcaagagcta caaggatgga tgcattaaat cttgagcttg
     7381 tttatcgtgc ggggatacta aaaggtgtac ttgattcagc atttgaaaat catttaaaaa
     7441 aagttgcctc atatgcttat aaaaaagcaa tgggtggacg gtcagggaca atcaatggtc
     7501 cagttttaga agaactggtt agaaccccgt ttgatggtta taactattca gaacagttgt
     7561 ggggcaatac tgacaatctt gttaagaatc ttcaaaagag attaaaacaa ggttttgttc
     7621 gtggcgagca tcctagagcg atggccagag atttagctaa gcgatttaat gttgctaatc
     7681 acagggctga aacactaatc agaactgatg gaactatggt gattaataat gctaccgcta
     7741 ggcgctactt gaatgcagga cttaagtatt atcgtgattt agttagactt gatgacagga
     7801 caactgagat atgccgtaca attgctaaag aaaacaaaag aaagctatta tctgagctaa
     7861 agcctggaat taatgtagca ccctatcatt tcaactgcag aacaactatt attcctgatg
     7921 aagatgagct aagtattgaa gtagaaccaa ttgatgataa aagcactaag tattttaagg
     7981 atgtcacctc agattggata gatggaaatg agcataaacc acaactgtca ctactaaatg
     8041 agtacgtaaa aaatggcact ccttacaaag tagatggcca tagtgtcgtt cttgatcatt
     8101 cgaattatga atatagagtt gctaattggt tatccaaaaa gacaggattg caagttgaca
     8161 tggtgccaag agttaattcc cctgaacata tcaagactcc tgattattta gttgatggag
     8221 ctccttttga tctaaaagaa atcacaggtt cgggtaaaaa cgtcattgat ggcaatctac
     8281 gaaaagcaaa aaagcaggca actaatatca tttttgatat aacaaaaacc cctttatcat
     8341 ttgaagagat aatggggcaa ttagaacata tttatatgat agatcgtagg ggtcttgata
     8401 tatcaattat caaaaataaa gatgaggtat tagctgtatt agaaaaagaa ggaggatgac
     8461 ccaccgcctc cacagtaaac tgcttcatgg gcgttagacc atcatccttc tttatctcaa
     8521 ttatacatca ccctattaaa actatcaagg aggaaaatat gtttatttgg caaatggtat
     8581 tagtggcact aggtgtattg gtactcatat tgattgttgg cattgcagca atagcggtta
     8641 agtcaattat tgcagaattg aaaaaagaag gataaaacaa tgaataagcg cattaagaaa
     8701 aaacgtaaat tggaaacagc ggttgtgatg cttgttgcag agaatgccat gcaagcagaa
     8761 gctattaaaa atcaaaacaa acaaatcatg gagctaaaat caatcgttca acgaaacgct
     8821 ctggcaacaa acgaagagtt agcgactgtt aaagctgcta ctttagataa ccaatcagtt
     8881 atcaaggcaa ttggtgacac ggttgactat attaagaaaa actacaaacg gaagtagggg
     8941 aaataaagtt taaccgtgtc gaatttgacc tctttacaaa tctaaaccaa agtcgtagca
     9001 atacggcttt ttattgtgtc caaactttgt tgatgacact aaaagctaca ctgtttcgtc
     9061 gcaggacgta aagctagact atcggttggt ggcgtaacca ctaggagaaa gttatggcag
     9121 aagaaaatgt aacaacagag acaactgagc aagtcgacac tcaaaaagaa gctgttgaac
     9181 atcctaagca tgaatatgag cgaactttta ctcgcgcaga catctcaaaa atgatggctg
     9241 ctgaacgcac taaatgggaa tctgaacaat ccgcagctat tgaaaaagct cgtacagaag
     9301 gtgaacgttt ggccaagttg tcaaaagatg agcgcgctaa agaggaggaa caaaaacgtc
     9361 tagatgctat cgcagagcgt gaaaaagcag tagcagagcg tgagatgcgc attgagacgc
     9421 attccctgct tgtggagaaa ggattgccat tggattttat tgatattgtt ttagccacta
     9481 ctgcagaaga ggttaaggcc aatattgata atttacaaac tatttttgat aaagctgttg
     9541 aaaaacgtgt taacgatcgt ttaactcaga aaccgccacg aactggaaat ggctcggtcg
     9601 gtatgactaa ggctgacatc atggcgatag aggatgacga cgaacgtatg cgtttaattg
     9661 ctgagaatcg taacttattt taagagggga atattatggc tgaaaaaaac ttaaacacta
     9721 tggcggactt aggagatatt aaatcaattg attttgttaa caagttttcc aaaaatatta
     9781 atgatttact aaaattgcta ggggttactc gtcgtgaaac attaactaac gatctaaaaa
     9841 ttcagaccta taagtgggaa gtgactttag atcaaactga tcctggagaa ggggaaacaa
     9901 tccctctgtc taaggttact cgaactaaag ataaagacta tacagtgaag tggttcaaga
     9961 aacgtcgtgc aactacagct gaggcaattg ctcgccatgg tgcagctcgt gctattactg
    10021 aagcagataa gcgcattatg cgtgagcttc agaatggaat taaggatgca ttctttacat
    10081 tcctcaaaac aaaaccaaca aaagttaaag gcgttggcct tcaaaaagcg ctgtctgcat
    10141 catgggctaa gctagctact tttaatgagt ttgagggttc cccgcttgtt tcttttgtct
    10201 ctcctttaga cgtagctaac tatcttggag atactaaagt aggtgcggat gcctctaatg
    10261 tttttggaat gacattgctt aagaactttt tgggtatgca aaatgtgatt gttatgccat
    10321 ctgtgccaga gggtaaaatc tactcaacgg ctgtagaaaa tctagttttt gcatctttaa
    10381 atgttaaagg gggagacttg ggcggcttgt ttgctgattt tactgatgag acaggtttaa
    10441 ttgctgcagc tcgtaatcgt cagctttcta atcttaccta tgaatctgtt ttctttgggg
    10501 cgaatgtact gtttgctgaa attcctgaag gggttgtaga ggcaacaatc gaagctgctg
    10561 ctgtacccgg cattggtggt taaaggctat ttatatgggt gataaacaac ttattgacga
    10621 tatcaaactc tttataggta tttccaaggg tgatggtgcg caagatgagc tcatcaccct
    10681 tgctatatat gaaagtaaag agcgtgtgct agctaaactt aatgaatact cagaaactga
    10741 aatcaccaaa attcctgata gattgaggtt tattgtccgt gatgttgcta ttaaacggtt
    10801 taataggatt aattcagaag gagccgttga agatagcgaa gaaggaaaga cttttaagtg
    10861 ggacagttac cttaaagagt atgaatcaac actcagaagc gctgctattg ggaaggtata
    10921 ttcaggcaaa ggggtagcaa gatttattta ggagatacac aatgatctat aaagatagag
    10981 taatcttagt gtatgtcgat gaacaggacg attttctaga taaaagaact gttgaaaaac
    11041 ctagcgggaa aatcccctgt atggaaaata ctttcacaaa atctgaacag atggggctat
    11101 ttggtaaata tgatttgaat gcttttaagt tgcacttgca aggccattac gacggcttta
    11161 gcaagattat ctacaaggga aaatcgaggt tgataaaggg actagcacac cataaaaata
    11221 gcacggttat ttatgtatga gtcttattta tcggatgaga ggcctagata ggtttttacg
    11281 cagcgttgag cgcaagcaga agtcagtacg aatcgctgta gataaagagc ttagtaaatc
    11341 agctgctagg attgagagac aggctaaaat actagccccg gttgacactg gatggctgag
    11401 agctcaaatc tacagtgagc aacaacgact cttacactat agagtggttt ctcctgcttt
    11461 atattctatt tatcttgaat taggtactcg taaaatggaa gcacaatcgt ttttagaccc
    11521 tgccctgaga aaagaatggc ctgtgctaat ggctaatatc aaaaaaatgt ttaagaggtg
    11581 atgcatggat tactcactgg aaacactata tttaaaaaag gtaaaaaata gattgggagt
    11641 tttagacata ccaatctatt ttaaattgcc taaatcagac gttttagagc cttttattgt
    11701 tgtaggtaca aatatatcag acttgtcaaa aacagctcaa actggagcag ttattgatga
    11761 ttttagcctg aatatcgatg ctttcttacc tggcgatagt cgtttggatg cagaagagat
    11821 aaaatctcgc atgcttagac tgcttgggcg aaataaccaa ataaaggctc agattttggt
    11881 agataattca ataggacgag aagtctatag agttgctatc aacattacag aaacactatt
    11941 ttaaagggga cctaaatggc aaacacaaaa aaaggaacaa ctattgaaat tacaacaggt
    12001 aaaccgattg taggaaaaaa gattttttac tttatacaat cagttgatgc accaaagaaa
    12061 agtcaggctc tgttgccagc ctatcgtacc gatggtacta caaccatggg tggtgaatac
    12121 attgatgagc aaacccaaca aggtcgcgtt attgagaagg ctacagatga acactctatt
    12181 gatttgacaa cgtactttgt accgacagat ccatctgttg ctgtcatcga ggaagctaag
    12241 aaaacaggta aatctatcaa aatttgggaa gttattgccg acgaaagtgt caaagaacag
    12301 attcaaattc ctgaatcgac tggacccaag aaagatgttt accctgctaa gtttgggtac
    12361 gccaagattg acgaaatcga acgcggtact ggtatttcag acttagtaga aatgtcctac
    12421 accgctaaca ttgtaggggc cttacaagat ggtaaattcc ctctcacgaa agaagaaatt
    12481 gaaatgctag aaaatgtata cggctatcaa aatccgggtg atactactgg cgactacgat
    12541 aatatcacta aatagcacac aggggtggca actgctaccc cattttgatt taaaaaggag
    12601 ataaaataat ggaatttaca gcagcaaaac gaaatatcga tattaaattt gattttaaaa
    12661 ctatgtttaa gatcaataat aaactaggaa caattaaccc agaaacagga gagcgcaatg
    12721 cagatggtgt gggtgctttg tttttcaata tcttagagcg taatgaaagc gccattgttg
    12781 accttgtgcg tttatctgcg ggaagcggaa aaaaagcgct aactgaagat gaaattctag
    12841 atgcaattgc agaagctgtt gatgaagaag gaacaacaga agggttgttt gctgagattg
    12901 aaaaagaaat ggttgattct ggttttttca gagcgaagat tttgaaatat atcgaaaaca
    12961 tggagaaatc agctcgttat ctcaaagcga aggacgatat ggacgcaact caaatccaaa
    13021 ttatcgaaga catgattgga agaatgagca acgcagtatc ttagtaaatt gcgcacggct
    13081 agggctcaca gacattgata ctatctataa atgtactaag tgggagctag aggctattat
    13141 ggaggggctt gagtataagc agcttgctga gcgcgagaac ctctctgaat tgtctctaaa
    13201 gcttagatat acattaaatg ctaaaaaggt tgatgtaggt aagctcaaat acgataagca
    13261 taggctaact atcaaaagat cgtatcaaaa agctagccgt agccaagccg atagtgatag
    13321 cagtattgtt gagagaatac aaatgcttaa taatcatttt caaaatagat agataaggag
    13381 gagtagatgc caggaacatt tgatggttct attttcgctg atgttggtgc caacacaaag
    13441 gactatgagc aggccatggc tcgtattgtt agtacgactc agaatacttt cagaaaagcc
    13501 caagatacag cggttaacag tagtaataaa atggttcaaa tcattggaca aatcatggcc
    13561 caactggcga acaacggcga atcgctcggg aagagacttg gctctgccta cgctactggt
    13621 ttaaaactga gcattggtga aattcaacgc atagcagctt ccattggcga aaaaattccc
    13681 gaacccataa agaatggttt tcaaaaaatc attattccag ttgcaagtgt tattgacaaa
    13741 atacggggta acttaaccgg tttcattaat caaacaaaaa tgcaacttca gaatcttgtg
    13801 ggtattggta agataagatc tgcatttgcc aaggctgcga ctggagttga tatcttaact
    13861 cagagggcaa gtagtaagct taataactta tctgcaatat tcgaaacggt cgcaggcaag
    13921 cttccgcgac cattcggaac agcgtttaga aaaattgcct catccgtttc taccttgaat
    13981 agctctatac agtctgttgg agggaagatt tctaattcac ttggtcagca agtcttgaac
    14041 ccagccttac agtcatggaa taattttttt agttctgtat cagctaaggc gtctgctttc
    14101 gcaaacaaag tgagtactag tttgtttggt cggctgacct caagtttagc taatttatca
    14161 agtaaaatag ggagcagtct tagcaatggt tttagcagaa tgtctagttc tgcggctact
    14221 tccttgaatg gaataagcca gaaattcgcc aatacctctt ctgctggaga gagactcaaa
    14281 agtacagtga tgagcatcgt gcaggccttt agtttaatgg ctgttgctca aaaagctatg
    14341 cacgctatta ctggggcaat agacggggcg gttagtcgcg ttgataccat gaaccgcttt
    14401 ccgaaaacga tggcgctatt tgggtattct gctgaacaat ctaaggcatc aattgataag
    14461 ctatcaaaag gaattgaagg tctgccaact cctctagaca gtgctgtaaa aagcgctcaa
    14521 cagctcgcca taaccacagg aagtttagat aaagggacta gtttagccct cgccttcaat
    14581 aacgcaatga tcggttacgg ggcaacaact gaaggggctg agcaagcact caggcagttt
    14641 aaccagtcgt tggggtctgg aaaaattcaa gctgaagagt ttaactctgt atcagaagct
    14701 gcgccaggtt taatgtctaa aatggcggaa gccttcggtt ttggtaaaaa tggcgtacaa
    14761 gatttaaaat cagtcttatc tgatggcaaa atcactgcac aagagttcgc agataaaatg
    14821 attgagctta acgatgccca aggcggattt gcagagatgg cccaatcatc ggctggtgga
    14881 atccgaactg catggaagaa cgtacatacc gccgtcgtaa aaggcgtagc aggtatgatt
    14941 tcagcctttg atgaagcggc taaagctaat ggcatgaaga ccattgctga aacacttctt
    15001 agtctgaagc cagcaataac cagtgttttt gatacgatta attctcttat tccaaatgca
    15061 gttgcagcat tcgctaggct aaaacagtct atcaatattg actttagccc attaggcgcc
    15121 agcgttaaag aggtgtttgc tcttattaat attgtttttg gagattttgc acatactggt
    15181 gaattatcag agcaggcttt tgataatcta aaagcaaaaa tcacttcttt agctcctaaa
    15241 gtcattgccc tttgggcagt gatgaacccc gctagcgcta tatcaacgat aatgcctttg
    15301 ctttctctat tcggaaaagt tggtctagct ttaggaagct tagggacttc tgtcggggcg
    15361 tttggcggca taatttctag tgggatagct agtgccagcg gcgttgttgg tgcctttgcg
    15421 gcaactctaa gcggattacc tggcgttttt gctaccgcag cagggcgtgg gctatctgtg
    15481 cttggaacta tgacaagcgc aatgtccagt cttgtgagtt tagcactggc ggccatagga
    15541 ccggccgcta ttctaggtct tgtggtggca ggacttggtt tgattaatag tcagtttggc
    15601 gcacaaatcg agcagctact taacaccgca gttacaaaag gtcctggcat tattcaaggc
    15661 cttgtaaaag gaattacttc taaaatacca gttttgatag ctagtggcac tcaattgatt
    15721 gctaaatttg caaatgctat cgcagtgtta ttaccagtta taattcaagc tggcgttcag
    15781 ctaattacga gtctcgtcca aggtattgga caaaatgcaa cgaatttaat tagttcagca
    15841 ataaaaatca ttggtagttt tgttagttca attgcgagtg cattgccgca gcttatttct
    15901 gttggaatgg agctattatt aaatgttgtc aacggcatag ttcaaaatat acctcttatt
    15961 atccagcaag cccagcaaat tattgatagt tttgggaata gtttacaggc taaccttcct
    16021 agtattatta gcaacggtat agctattttg gtgaatcttg tacagggaat tactcaaatg
    16081 ttgccaactg ttctgcagat agctactcaa gtcattacga gttttgtatc tggaattgta
    16141 cagtttttac cgcagttact tcaaggtggc attcaaatca ttattagcct tgtgcagggg
    16201 attattcaaa atctacccca gattgcacaa tctgctgtac agattataca gtctttagct
    16261 tctggactga cgcaagctct acctcagatt atcgcagcag gcattcagct tgttgcgcaa
    16321 ctagccgtag ccttgataaa ggggcttcca cagattattt ctgcgggtat tcaattaatt
    16381 atggggctcg gtaaagccat gttaggggct atcccaaacg ctctttcagg agtttgggaa
    16441 ggtattaaga gcggattcag ttcgatgtgg gaccaaatca caggtaagag ttccacaagt
    16501 acagctaaag tctctgcgga cgccacggtc atggccatga atgttgggat gcaaacgaca
    16561 gctatggcta atcaagctaa tacagatacg acatctatgc ttaatagcat tagtcaaaat
    16621 acagagcttg ctaatataaa cgctacatca aatgccacac agatggctaa taacgttaat
    16681 gctcagacag gaacgatgag tcttcagggg ttgaatgatt cgatgtctct tgcgagtggc
    16741 attagcacta atatgtctgt cgctaatata aacgctacta ctcaggctcg agaaatggct
    16801 tcaggggtta atggtgcgac ttcttcaatg aatctagacg ccattaatca tacgctcagc
    16861 ttagctagtg gtgttggtgc gaacatggga gctgctagca caggtgcaac ttctcaggcg
    16921 caagctatga gctcaggggt gagtaacagc ctggcatcaa tgcagtcaaa ctcaactaaa
    16981 gcagcctctg gtctgtctaa tagtgtgaca agcgaaatgt cttctgcagc aacctctgca
    17041 acctcaagcg ttaataggtt gtcctcggcg gtcgagtctg gcttcaataa ggcgaagact
    17101 tcagcaacaa cctcaatgaa tgggatagcc aatgcggtta aaacaggatt tagtagcatt
    17161 aacagtactg caaagcaatc tatggcaaac cttgtaagtt cagtgacttc tgggatgtct
    17221 cgtgcaaccg cggtgtctaa taatgcttgt cagaagatcc tctcaatatt cagggctttg
    17281 gcagggcaga tgtcttctgc aggagcttat gcaggtcaag gttttgctaa tggtctagct
    17341 agtagcgcag gcacaatcta cgcaatagct aacagcattg ccgctaatgt agcagcaaca
    17401 attagacgcg ctttagatat tcactcacca tctcgtgtca ctaaaacact aggtgcattt
    17461 actggagagg ggtttgccct cggtatggca gagtggatag gtgagatcaa tagcctaggt
    17521 aaagcatacg caacagcagt tactgatcaa aactgggggg taaatagtac tgtttcaaca
    17581 tctgctaaag ttaataatag tggaatcaat acctctcttg ataatcttag cgaagaggtt
    17641 aggcagtctc aattgtcaga gcctatcttt gaagtgcata atgagattgt tggagataaa
    17701 atttacacgg ctgttaaaga aaaagaatca agagagcaat ctaaagattc ttattttgtt
    17761 tttgactaga agggagtatt ttggatttat taatagaaaa agagagtcag gcaactaggt
    17821 tgtctgactt tggtatttat aatattgcta ttgaagatag cgctccttta ctatctgtat
    17881 cacaccgagc agtcaaagga aggagtggtt acatctacga tggggctact tttacgacta
    17941 aaacgcttaa ggtcaaagga agagtgacgg taagcaacgt ggaaagactt ttggacaaac
    18001 aggacgaact aaacgctctg cttgttgttg acgaaccttt ctacgtgact aagatgtacc
    18061 ctgaaaactc agatctattt aactttgagc ttccagggga aagcacagga gacctgcaac
    18121 ttattggctc tcctcataaa ccttggaaat atagatttaa agtcatctta gacgacacta
    18181 tcgcttatga atttatagga aaaaccagtc aaggactaaa atataatctt tccttcgcgc
    18241 taagaactgc tgaattacct ttcggtgaga caaagccaaa ggacataact ctatcagggg
    18301 gcagttttgc ctatgcagga accgctaaag caagtcagct agagtggcct tttattatag
    18361 agcttactcc ttctggaggt cagactaatt tttatattga aattgatggc aggcgctttg
    18421 agtttaagca gaatagccag ctacaaaata gtgataaatt acttttgaca ggcatagcta
    18481 ccacactaaa cggaaattat gtcaatgcta aaacgaacta tgagtatttt atcttcaatc
    18541 ctaatcctaa caagagaatt acttacaaaa cggattttct tggcacgatt aggattttaa
    18601 attttgtaga gttgtataaa tagggaggtc taatgattac ttttttggat catcgtgaca
    18661 ttgagtatgg ggtcattagt gtcattaggc atactaatgc tgttaatggt gagcgctcag
    18721 tgagcgggga aatttataca aacagtgatg tcctcaataa tatcgataga gggtggcgac
    18781 ttagatttga agatgagtat tacgttgtta tttacgcaaa gcctgttgat gttggtcaaa
    18841 aaacgcaagt ttcgtttgat gccatacacc aatttttttg ggacttcagc aagagtagta
    18901 tctatgaggg tctcggagat gggtctcata ccattgatac ctatctagag acagtattta
    18961 aaggtagtgg gtaccgctat aagctagaag taggtgtgaa cgcatttaga aaacaatctt
    19021 ttaattataa gtccaggtta gatttattca atgagattat taaagcgacc ggacttgaat
    19081 tttcagtcag cgggaaagtt gttcggctat taaaaaacat aggtactgat ctgtcaacag
    19141 tggtacgaaa aaatttcaac atgaatgacc ttaccattga aaagaatatt gatagcttta
    19201 ttacctatca gaaaggcttt ggtgcatgga ccgacccaga ggaccactct aaggggagac
    19261 ttgaggcgga atacgaaagt cctcttgcca aggagtacgg tcgacttgaa ggggcgcctc
    19321 tgacggatga gcgcttcacg gtggcagata atctaaaaga agctttaaaa agtaatgttg
    19381 aaaattcata taagatatca gtaaaaattg atatggaaga tttaacgaga gctgggtata
    19441 gatgtgagag gccggttgct ggtgactaca ttatggcgat aaatgagact ttaggttttc
    19501 aagagcgtat acggatagtt tcttttacaa gctactacga cgcaactgga gctttagtaa
    19561 aacatgaagt cacttgtaat gatatcggat ctgtgaaaaa acaaagcgta ggaagtctgt
    19621 ctataaacag tagaatcaat cagatagatg cagatattgc ttctgcaatt gaagtagcaa
    19681 cacaagcact agtatctgct gacgggaaaa atactgttta cggtggcaca gaaatgccca
    19741 aagatgaacc aaaaggaacc ttaaaaaaag gagacatatt attcctaaaa gttggcgata
    19801 ctactagaat gtatttctgg aatggtgctg agtgggaaga acctgaggtt gtgaacgacc
    19861 cagaacgatg gcgtgaagac ctcgaaaaac aaatctctga ggcgatcgaa aaagccaaaa
    19921 aagcacagga agaaatcaac caacgcaccg ataaagagct tgaagaattt agagccgccc
    19981 tcaaaaacct agcgttacca gaggaagcga ttaaaaaaat cacagaggct ataaaagttg
    20041 atgacatccc gtctattaaa caaagctttg atgacctcaa aaatagagtg agtgagacaa
    20101 gcgaagaatc tcgtttaact gccgaaattt tagggaacaa cggtaagaca cgctacaaca
    20161 aaaatttgct ggtcggtgag cctaatcgtg ttaaaaaaat tgatgaggat tttatcgagg
    20221 tagaagctaa tgatggtggt ttcaagcgtg gcgagactta cacaatcagc tttagtcaga
    20281 catgtgagcc gctcaaaaaa gtggctatca cgctgatcca agctaataat aagggagtta
    20341 aactggtact gacacctact aaggcaaaaa tggagcctga gacttttact ctaattaagg
    20401 acacagaggt catcaacgtc tatcctttga gctactcagt cactttaagt ggtgactggt
    20461 acaaatctaa gcaagtagat ttaaatgcgt cggaggtgcg aaatatggct ctggggatga
    20521 gttatagaga tgtggttgat ggtaataatg ctgatttaat tttggactgg gcggaaaacc
    20581 cagatattat ttttgacgga aacggaggta tttaatgtca aaagaagttg catcagcaag
    20641 gatacagcat agaggcatga ccaaacaaga gtgggaatca agctccgata tcttaatgga
    20701 gcgagaaatt ggaattgata tgactacggg ttacccaaaa gttggtgatg gcaaaaataa
    20761 gttcaaggac ttaaaagact tgcgcggccc tatgggacct caaggtcctt caggagaaag
    20821 aggcctaact ggcccaattg gtcctcgggg ccctgctggc aagcctggaa cgacagatta
    20881 taatcaactc caaaataaac caaatctaga tgcgtttgca caaaaaaaag aaactaatag
    20941 taaaatcacc aaattagaat caagcaaagc agataaaagc gctgtttact caaaagcaga
    21001 gtcaaaaata gagctagaca aaaaattgag tttgacaggc ggcatagtga caggacaact
    21061 acagtttaaa cctaataaaa gtggtattaa accctcatct tccgtaggag gagcgattaa
    21121 cattgatatg tctaaatcgg aaggtgctgg tgttgttgtc tattctaaca atgataccag
    21181 tgatgggccg ttaatgagct tgcggacggg taaagagacc ttcaataaat cagcgctttt
    21241 tgtcgattat aagggaacaa caaatgccgt taatattgtg atgcgtcagc caaccacccc
    21301 caatttttca tcggcgctta atattactag cgacaatgaa aatggtagtg caatgcagct
    21361 acgagggtca gaaaaagcgc taggaacgct caaaatcaca cacgaaaacc caaacgttga
    21421 ggcaaaatac gatgaaaacg ctacagcgtt atctattgat atcgttaaaa aacagaaagg
    21481 cggaaaaggt actgctgctc aaggaatcta cattaactca acatcaggca cgacagggaa
    21541 gttgcttagg attagaaacc ttagtgatga taagttctac gtcaagtctg acggtggttt
    21601 ttatgccaag gaaacttcgc agattgatgg caacctgaaa ctcaaggacc ccacagcgaa
    21661 tgatcatgcg gcaaccaaag cttatgtaga taaagcaatt tctgagttaa aaaaactcat
    21721 actaaaaaaa tagattaagg aggataaatg agcagagacc caacacttat tttagacgag
    21781 tcaaacctcg ttattggtaa ggatggacgt gtgcattaca catttaccgc agaggacgac
    21841 aacccaaaag tcagactagc tagcaagtgt ctaggcacag cgcattttaa tcagctcatg
    21901 attgagcgag gagaccaagc tactagctat gttgcgccag tagtagttga gggtacaggt
    21961 aatccgactg gactatttaa agacctcaaa gagattagcc tagagctgac agatactgct
    22021 aattcccagc tttggtcaaa aatcaagctg actaaccgtg gtatgttgca ggaatactac
    22081 gacggtaaga tcaagaccga gatagtcaac tccgccagag gtgtcgctac acgtatcagc
    22141 gaggatactg ataaaaagct agcgctcatc aatgacacca ttgatggtat caggcgtgag
    22201 tatcgagatg ctgataggaa gctatccgca agctatcagg caggcatcga ggggctaaaa
    22261 gccacaatgg ccaatgataa aatcggttta caagctgaga ttaaagcctc agcacaaggg
    22321 ctatcgcaaa agtatgatga tgagttgcgc aagctatcgg ctaagatcac aacaacctca
    22381 agcggcacta cagaggccta cgagagtaag cttgcgggct tacgtgctga gtttactcgc
    22441 tcaaatcaag gcacgaggac agagctcgag tcacaaatta gcgggctaag agcggtacag
    22501 cagtcaacag ctagccaaat ctctcaagag attagagacc gtgaaggtgc tgtcagtcgt
    22561 gtgcagcaga gtttggagag ttaccaaagg cggatgcagg acgcagaaga aaactatagt
    22621 agcttgaccc atacggttag agggctacag agcgacgttg gatctccgac tggtaaaatc
    22681 caatcgcgcc ttactcaact agcaggacaa attgagcagc gggttactag agatggtgtc
    22741 atgagtatta ttagtggcgc tggagacagc attaaattag ctatccaaaa ggctggcggc
    22801 attaatgcca aaatgtctgg taatgagatt atctcagcaa ttaacctcaa ctcctacgga
    22861 gtaacaatcg caggtaaaca catcgctctc gatggcaata cgactgtcaa cggcaccttt
    22921 accacaaaga tagcagaggc tatcaagatt agggctgatc agattattgc aggcacgatt
    22981 gacgctgcta ggattagagt gattaacctt aacgcaagta gtatcgttgg tttagacgct
    23041 aactttatca aagctaaaat tggctatgct atcactgatt tgctcgaggg taaggtcatt
    23101 aaggctcgta atggagcgat gcttatcgac ttaaatacag ctaagatgga ctttaatagc
    23161 gatgccacaa ttaattttaa tagcaaaaac aatgccttag tacgtaaaga tggcacacat
    23221 actgcctttg tacattttag taatgcgacg cccaaaggtt atacagggtc agcgttgtat
    23281 gcatcgatcg ggataacctc atctggtgac ggtgttaact cggcttcttc cggtcgtttt
    23341 gcagggctaa ggtcatttag gtacgctacg ggatataatc atactgctgc agtcgaccaa
    23401 accgagctat acggtgataa tgtcttgatt gcagatgact ttagcatcaa tcgaggattt
    23461 aaatttagac cagacaagat gcaaaaaatg cttgacatga acgacttgta tgcggctgta
    23521 gtagccttag gccgctgttg ggggcacttg gctaacgtcg gctggaatac tgctcatagc
    23581 aattttacaa gtgcggtcac taacgagtta aataatcata tcaacaaaat ttaataggag
    23641 aaacaatgga tttaacgctt aaaaacaaag atttaaacac actatatagt gtactagaca
    23701 aaatcaaagt cacgaacatg cgagcaaacc gcggacgtgc taagctactc gcaaaagtag
    23761 tcgataaatt caaagagtac gccaaggatg agggtgacct tattgatctg tatgctcaaa
    23821 aagacaaaga tggcaagttt gtcattgatg agcacaaaaa catcaagcta gcagaccccg
    23881 ctaaactcga cgagttcaac ggcctactca acgagctagc tgatgaagaa attgtgatta
    23941 aagggggtga gtactccaag cgatttattg actttttaaa ctttttagaa gagtgtgaag
    24001 atgaatttac atcatctgaa atcattctta tcgacaacat tttggaacaa tttgaagaaa
    24061 gtaaaaaagg agaaaaacca tgagaaattg gaaagtgaca ggaaaatacc cacaatttga
    24121 cagcacagga gcagtcgcaa gcacacatat tattatcact gctgaggatg gctcagtcat
    24181 ctctcaacca atcaagcagg gcttaacttc aactaatgac acagagatta tcaaagctac
    24241 tttggaagaa tttaaaaaat ctgaatacgt cgaaatcgct atgggcgaag ccgtgcaaaa
    24301 agtagacgac cttgaaaaaa tctcacagga aaccgctaag accgctaaaa cagcccaaac
    24361 agccgcagga ttagctaagg tgtccgcaga gcgtacacag cggatgatta acttgcaaac
    24421 catccacgta ttgacaagtg gtgggaaagt tgaacccgat atctacaaag gtatgttaga
    24481 gcttattgaa cctgctaaac aaggcgagta tcaggcttat gacgtgttta ctgttgtaga
    24541 tgagtcgcac gaagatcaag cgggagaagg taatcttgtc tttgtacacg ttaacgagcc
    24601 gtttacttat gacaaacaga cgcttaaaga gctagaggaa gaggataaag tcacagtcat
    24661 taagtatgcg gacttagtta agcaggatta gcgaggtaag ctatggcaac agagttgata
    24721 tttggtcttg gtggctttat tttagctatc gtcacgactt acaatatttt taatgcaaaa
    24781 tccatcaagc atgcgacaga tattactttg ttgcagtctg aagtagagca tttaaaaatt
    24841 gttacacgcc aaaatgctcg gcgtcttgag gagcatgatg agcaaaacaa aacgctcatc
    24901 acaatgacag agcaaattaa aaacctcaat cgtgaggtaa gagaacttaa agatattatg
    24961 agaggtgaag catgatcaat ttaaaattac gactacaaaa caaagtaacc ttgatggcta
    25021 ttttaggagc tatcttttta ctggcacagc aattaggtat taaactacca tcaaacatcg
    25081 cggatattgc aaacacagct gtaacgcttt tggtattgct cggtgttgtc acagatccaa
    25141 ccacgaaagg cctgtcagac agtgagcaag ctttgactta ccacgaacca aaacaatagg
    25201 aggggacatg cgggcaatca cacgattagc attagttata gcaatagcaa tactgtatgt
    25261 gccattatct gttgttgctt tgattttaag cccattttta gataaggagg gataaatggc
    25321 tacatatcag gaatataaaa gtcgttcaaa tggcaatgct tacgatattg atggatcgct
    25381 tggtgcgcaa tgttgggatg gctacgcaga ctactgtaag tatctaggac tgccatacgc
    25441 aaactgtaca aatacaggat atgcaaggga tatatgggaa caacgtcaca aaaatggtat
    25501 tttaaactac tttgacgaag tagagactat gcaagctgga gatgtcgcaa tttttatggt
    25561 agttgcaggt gttacaccgt atagccatgt ggctattttt gatagtgatg caggtagtgg
    25621 atacggatgg tttttaggtc aaaaccaggg tggagcaaac ggagcatata atttagtaaa
    25681 aataccatat tcaacgactt atcctactgc atttagacca aaagttttta aaaatgcagt
    25741 tactgttata ggtaatatag gactaaataa aggcgattat tttattgatg tatcagctta
    25801 tcaacaagca gacttaaccg ctacttgtca gcaagctggc actactaaaa cgattatcaa
    25861 agtatccgag tcactcgctt ggctgtctga taggcatcag caacaagcta atactagtga
    25921 ccctattggt tattatcact ttggacgatt tggaggagat agcaacttag cgcaacgaga
    25981 agcagattta tttctgtcca atttaccaac caaaaaagtc tcttacttag tcattgatta
    26041 tgaagactct gcaagtgccg acaaagaagc taacactaat gcagttattg cgtttatgga
    26101 taaaattgca aacgctggat ataagcctgt ttattacagc tataaaccat ttacgcttaa
    26161 taatattgat tatcagcaaa ttatcgctaa gtacccaaac agcatttgga tagctggtta
    26221 tccagactac gaagtacgaa cagagccact ttgggagttc ttcccttcaa tggatggtgt
    26281 gcgctggtgg cagttcacaa gtgtaggagt agcaggtggt ttagataaaa atattgtatt
    26341 attagcagat gatagtagca aagtggatat acctaagatt gacaaaccac aaagccagct
    26401 tacttttaat caaaagctag atactaacac taaattagac aactcgaatg taccttacta
    26461 cgaagcaacc cttagcacag actattatgt agagtctaag ccaaacgcaa gtagcgctga
    26521 taaagaattt atcaaggcag gaactcgtgt aagagtctat gaaaaagtga atggatggtc
    26581 acgtattaac gcttctcagt ctgaccagtg ggtcgaagat aagtatttat ctaatgcaac
    26641 acaagtataa aataggaggt aaagctcctt tagataagac aaatgccctc gcttttgcgg
    26701 gggctgtttt tgttataaag attttaattg ttatttaagc attttcgttg atttttttct
    26761 tttttgtgct aaaatatttt gtgatttctt attattaaag aagaataggg tacacttata
    26821 agtgagaaaa attgtaaatg ttaattttaa aaagttttta acttcatctt ttctattgtg
    26881 ggtatttata tcagctataa ttccaacgtg ttacgcgtat gagatgagta gtgtgggagt
    26941 tattaattta aggaatttat actctacata tgatccaaca gaagtaaaag gaaaaataaa
    27001 tgaaggtccg ccattttcag gtagtttgtt ctacaaaaat attccttatg gcaatagttc
    27061 gattgaatta aaagtagaac ttaatagcgt agaaaaagct aaattttttt ctggtaaaag
    27121 ggtggatata tttactttgg agtattctcc tccctgtaac
//
LOCUS       DARYXS010000017        26999 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.017, whole genome shotgun sequence.
ACCESSION   DARYXS010000017 DARYXS010000000
VERSION     DARYXS010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26999
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.017"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..537)
                     /gene="hpt"
                     /locus_tag="TV193_000601"
     CDS             complement(<1..537)
                     /gene="hpt"
                     /locus_tag="TV193_000601"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEL1512827.1"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYS"
     gene            complement(542..1825)
                     /gene="tilS"
                     /locus_tag="TV193_000602"
     CDS             complement(542..1825)
                     /gene="tilS"
                     /locus_tag="TV193_000602"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEL1512828.1"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     KLQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHLRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFL
                     TVSKAELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIDLSAESRLLL
                     QAFDDLTKGLEFHRLNCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFAIKKIIPKTDLNREFKMVSYGDSLNYRGYRFVFSGSLTD
                     KGHDIAIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTSEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            complement(1822..3108)
                     /locus_tag="TV193_000603"
     CDS             complement(1822..3108)
                     /locus_tag="TV193_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEL1512829.1"
                     /translation="MKKLLAAMLMTFFVTPLTVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGK
                     ISKTADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            complement(3250..3621)
                     /locus_tag="TV193_000604"
     CDS             complement(3250..3621)
                     /locus_tag="TV193_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEL1512830.1"
                     /translation="MKKPSIVQLNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMF
                     LFILPTYNLVKGYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYAR
                     AKYYLSREGEVIYPTPGLLPK"
     gene            complement(3608..3880)
                     /locus_tag="TV193_000605"
     CDS             complement(3608..3880)
                     /locus_tag="TV193_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEL1512831.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKLN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRISSDEEA"
     gene            complement(3911..5422)
                     /locus_tag="TV193_000606"
     CDS             complement(3911..5422)
                     /locus_tag="TV193_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEL1512832.1"
                     /translation="MRLNLEKLPHKTKQSSLLIVISGFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCYTSFLLSGILV
                     LSHKALASWMGAQQLAPSIVITAMVLLIVPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIVAALCYRVLGWTVYLTANVAAFGNLVASLVILAYLKRHSAYSLKSFLSGDTV
                     AIRDLTSLGLPTLVFLLFSIYLLVFQLIDSLLVKNILVSSGLSEITAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTVLFHIKRESYREQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVVYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYAVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLGVFKEKLWSFLPFVKEK"
     gene            complement(5391..8885)
                     /gene="mfd"
                     /locus_tag="TV193_000607"
     CDS             complement(5391..8885)
                     /gene="mfd"
                     /locus_tag="TV193_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEL1512833.1"
                     /translation="MDILELFNQNKSIQTWQCDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSALLDEGSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDNVVKKLVKIG
                     YQRVAQVLSPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDIESQKSLQKKD
                     STSIKPASDMIFEPEDFDRASHNLEKQLQLAKAEHKGYLEELLTVTKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDRNAKFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKVYSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLEAYQCQLPLVSADAIVLHQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGVHRDYVTIQYQQSDRISLPVDQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQRAFEEDFAFVETDDQVRSIKEVK
                     KDMESVRPMDRLLVGDVGFGKTEVAMRAAFKAIGDHKQVAILVPTTVLAQQHYENFRE
                     RFENYPVEIAVLSRFRSKKEQSESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTVDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMDRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKR
                     DHQVMVRFEVASLQYYLTQDYFEALSKTSLKARISEHQGKIEIIFDVRRQKDHVILEE
                     LILFGETLGEIKSRKASS"
     gene            complement(8888..9457)
                     /locus_tag="TV193_000608"
     CDS             complement(8888..9457)
                     /locus_tag="TV193_000608"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL1512834.1"
                     /translation="MVKMIVGLGNPGSKHQQTKHNVGFMAVDRLVKDLDVSFTEDKTF
                     KALIGSTFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            complement(9616..10731)
                     /gene="ychF"
                     /locus_tag="TV193_000609"
     CDS             complement(9616..10731)
                     /gene="ychF"
                     /locus_tag="TV193_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEL1512835.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     AIPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDRSEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(10815..11180)
                     /locus_tag="TV193_000610"
     CDS             complement(10815..11180)
                     /locus_tag="TV193_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1512836.1"
                     /translation="MMTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATP
                     DLENLVTLAAVLEVTLDELVTGKEPAIKVIKKTEKPMNVWEFLTEESKRPMRKGDLLM
                     LLLVVIVLLGVYFIVIHFS"
     gene            complement(11301..11498)
                     /locus_tag="TV193_000611"
     CDS             complement(11301..11498)
                     /locus_tag="TV193_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEL1512837.1"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKKVLQP"
     gene            complement(11576..12712)
                     /gene="dnaN"
                     /locus_tag="TV193_000612"
     CDS             complement(11576..12712)
                     /gene="dnaN"
                     /locus_tag="TV193_000612"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEL1512838.1"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKNFKAVATDSHRMSQRLITLEKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKQFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            complement(12869..14221)
                     /gene="dnaA"
                     /locus_tag="TV193_000613"
     CDS             complement(12869..14221)
                     /gene="dnaA"
                     /locus_tag="TV193_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEL1512839.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQ
                     QLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
                     "
     gene            complement(14454..15227)
                     /locus_tag="TV193_000614"
     CDS             complement(14454..15227)
                     /locus_tag="TV193_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL1512840.1"
                     /translation="MTEILMHIPIEDIVANPYQPRLQFNQKELEELAHSIQANGLIQP
                     IIVRKSDVFGYELVAGERRFKAAKLAGLQKIPAIVKEISTLESMQQAIVENLQRSNLN
                     AIEEAKAYQLLIDKNKMTHEDIATYMGKSRPYISNTIRLLQLPDVIRQAIEDGTISAG
                     HARALLSLSTPKEQELYFHNILDQGLSVRQIEQLVKTKHPPKKRNKHKTIFVKSLEKE
                     LSKSLGLPVALSLQKNDSGQLQLSFSNQEELNRIINKLL"
     gene            complement(15347..16570)
                     /locus_tag="TV193_000615"
     CDS             complement(15347..16570)
                     /locus_tag="TV193_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEL1512841.1"
                     /translation="MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGA
                     TTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAASPAISNPYINLFGEENDTSAVQK
                     EDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
                     DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVT
                     SRNEAGETISTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGI
                     GFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQLNIPTSVTSGVVVA
                     STQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKV
                     DIKLTKTTKDLTKKQ"
     gene            16780..17259
                     /gene="rlmH"
                     /locus_tag="TV193_000616"
     CDS             16780..17259
                     /gene="rlmH"
                     /locus_tag="TV193_000616"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEL1512842.1"
                     /translation="MKIKLICVGKLKEAYLRDGIAEYQKRLSRFCQCDIIELADEKTP
                     DKASHAEKQQIMAKEADRIKKKLGQRDFVIALAIEGKQLASEQFSHLLSEVTVKGYSD
                     IAFVIGGSLGLDQSIKNRANLLMSFGLLTLPHQLMRLVLIEQVYRAFMIQQGSPYHK"
     gene            complement(17559..17632)
                     /locus_tag="TV193_000617"
     tRNA            complement(17559..17632)
                     /locus_tag="TV193_000617"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17596..17598),aa:Arg,seq:tct)
     gene            17913..17984
                     /locus_tag="TV193_000618"
     tRNA            17913..17984
                     /locus_tag="TV193_000618"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17946..17948,aa:Glu,seq:ttc)
     gene            18017..18090
                     /locus_tag="TV193_000619"
     tRNA            18017..18090
                     /locus_tag="TV193_000619"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18051..18053,aa:Asn,seq:gtt)
     gene            complement(18351..20936)
                     /locus_tag="TV193_000620"
     CDS             complement(18351..20936)
                     /locus_tag="TV193_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEL1512843.1"
                     /translation="MTKPKAWSLVYDIASFLLPFLIMFFVLLSMGISYGSEKTILASD
                     GFHQYVIFAQALRNILHGADSIFYTFTSGLGVNFFALASYYLGSLLSPLVYFFNLQSM
                     PDAIYLLTLIKFGLIGLAAYFSFHRIYPKIKPFLVLTLSVSYSLMSFLTSQLELNNWL
                     DVFILLPIVLLGLYRLITQTKPLLYYSSLSLLFIQHYYFGYMVAIFIFLLFLVNLISL
                     DTWKRRLRACLSFTSVSILSALTSAFILIPAYLDLTAYGETLSPINQIIIKPIGAFDL
                     LAKLSLGAYDTTKFNAIPMIFIGLLPSLLSIVFFTLKSISWRLRLGYGLLLGLIMASF
                     YLQPLDLFWQGMHGPNMFLHRYSWSFSIIIIILACEALSRQKDITNTRIIFAFILLSC
                     LLTLPYLTMDQYSFLQPSLLILSLAFLAAYLILLLSMQKTSVPMPFLIFFTLLFSCLE
                     TSLNTYYQLNGIHHEWVFPSRKGYSRALQDIDRLVKKTADSNDQFFRLEQLLPQTGND
                     SMKYSYNGISQFSSIRNRHSSSLLDRLGYQSAGTNLNLRYQNNTLIMDSLLGIKYNLS
                     YHQLHKFGFSRIASSHHTTLYQNHYSSNLAILTDNIYKDVKLTVNTLDNQTKLLNQLS
                     GKRLTYFQLEPSKLISNAQVFNGRISGEAAENTSTTIVHYQVTVPNHRQLYLSLPNIS
                     FSNHNATAVRIRIDDQTYEYTTDNAFSFFDLGYFEKGRTLTLAIMFPKNKNISFATPH
                     FYSLNSDNYLAAMNAINQKEVTTYTRSNQVISHYKAKSEGSMIFTLPYDKGWTARLNG
                     RPVALKKAQGGFIRIDVPKGSGKLVLTFVPNGFTLGLLLSFIGILLYSFLHYYLLRQT
                     AKLKA"
     gene            complement(21059..22678)
                     /locus_tag="TV193_000621"
     CDS             complement(21059..22678)
                     /locus_tag="TV193_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1512844.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYSIMKEKDAI
                     YMKPDFSEEDGVRAAELEGSFAELGGWEAESEASQLLQNLNIPEELHYQSMSELTNGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKAEREMGNDFVTVENLSVTVDGDKI
                     LDNISFILRPGDKTAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSR
                     DFASDESILEWLRQFAAKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLLLDDPTNHLDLESISSLNDGIKDFKESVIFTSHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLENKDVQAKVAELWK"
     gene            complement(22758..23630)
                     /locus_tag="TV193_000622"
     CDS             complement(22758..23630)
                     /locus_tag="TV193_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1512845.1"
                     /translation="MKKRVMDLLFVTIGSFITAIGFNTMFVDNNIASGGMVGISVVIK
                     ALFGISPSLFLMLSNIPLLILCYFFLGKQNLIKTLYGSWIYPIAIRLTSQLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLLVIGYVISVMENGFDSSKNVMIISKEYQAIKAYITGVMDRGV
                     SKIPIRGGYTTSDKIMLMAIVSGYELPALQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KHYKLEDKDVLLPM"
     misc_binding    23752..23991
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            24047..25069
                     /gene="trpS"
                     /locus_tag="TV193_000623"
     CDS             24047..25069
                     /gene="trpS"
                     /locus_tag="TV193_000623"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEL1512846.1"
                     /translation="MTKPVILTGDRPTGKLHLGHYVGSLKNRVSLQNENKYKMFVFLA
                     DQQALTDHAKESEMIRESIFNVALDYLSVGLDPSKSTIFIQSQVPELAELTMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPAGFLVYPISQAADITAFKANVVPVGNDQRPMIE
                     QTREIVRSFNHTYKTACLIEPEGLYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRQKVMSMYTDPNHIRIEDPGQLEGNMVFHYLDIFGQKEDKADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRQRRLEYAKDKGEVFRMLEAGSQKAQAVAAQTLSEVKVA
                     MGIRYF"
     gene            25270..26751
                     /gene="guaB"
                     /locus_tag="TV193_000624"
     CDS             25270..26751
                     /gene="guaB"
                     /locus_tag="TV193_000624"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEL1512847.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVNLKTKLAKNLTL
                     NIPIITAAMDTVTDSKMAIAIARAGGLGVIHKNMSIAEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVAEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEQLVTAEVGTDLETAERILHEHRIEKLPLVDDNGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDK
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGTIRELHDNAQFVEMSGAGLIESHPHDVQITNEAPNYSMH"
BASE COUNT         8309 a         5393 c         5023 g         8274 t
ORIGIN      
        1 tgaatagact tcctctttta aaacaccgac ataagggaga tttctataat tttctgcgta
       61 atctaatccg aagcctacaa taaactcatt aggaacattg tagcacacat agtctgcctc
      121 aatgtctacc acacgaccct ctggcttgtc aaatagtgtg ataatcttaa cggaattagc
      181 cttacgatat ttgaacatgt cacgcaaata tttgagtgtt cgaccagtat caataatatc
      241 ttcaacaaag atgacgtctc ttccctcaat attggtgtca acgtctttta agattttaac
      301 ctctccactg ctagttgttc caccattata gctagaaaca accataaaat caatttcaac
      361 gtgagtgtca atgtgcttca tcagctcggc catgaatgga acagaaccct ttaagacacc
      421 gaccatcaag ggatttttac catgataatc ctttgtcaac tgctcaccaa gctccttggt
      481 cctttgaata atgtcatttt cagaataaag aattttttga atatcttgct caagcatact
      541 gtcacctttt ttctaattta tcaatataca gtttagccaa cattatatca tgtttagacg
      601 cttttctcaa atatgtttca tcaccaacca gcacaaaaat aataactcca gcctgttctc
      661 ctacgatggc attttgacgc tgctcacttg taaactttcc atcgatgaat aaacgtctta
      721 atttttttga aaattcacca agaaaaagcc tatctcctgc ctgcctatga cgtaaagtaa
      781 ctggtgataa gctatataaa gggatagcta tatcatgtcc cttatcagtc aaactacctg
      841 agaaaacaaa tcgataccct ctataattta gggaatcacc gtatgatacc attttaaatt
      901 ctcgatttaa atcagtcttt ggaatgattt ttttaatagc aaaagactct ttttcaatga
      961 ggagacaata agtattttta attggataaa tcccctgctt ttgtcgtctg atgatgtgta
     1021 aaagatcatc aaattgtgat tttttaatgg ctagctgtgg aaacgtttct aaataatgct
     1081 gaagcaaaaa aaactgaaca gcagctgatt gagctaaaaa acagtttaat cgatgaaatt
     1141 caagtccctt ggttaaatca tcaaaggcct gaagcagcag gcgactttcc gcagataaat
     1201 caatcaaaga ttgagtagct tgaggatttt ctcttttgaa atctggcagg taatgatgac
     1261 gaacacgatt gcgaaaataa gccatgctgt cattagaatg atcttcaaaa tgaaagggat
     1321 taggcagttc tgcttttgat accgttaaaa acggtcgtat caactgacca ttagcaaagg
     1381 gctgaacctc tctgatacca gctaaatgac gcaatcgact accacgaatc agtctcatca
     1441 aaatagtctc agcctgatca tcagcatgat gtgctgtgac taaagccgaa taatgctcct
     1501 gctgcatgat ctcttcaaaa aattgatagc gaagatgacg cgcagcattc tcagaaaaag
     1561 cgccctgaaa ataagcaaca tagataggaa tagcatgctt tttagcccaa gacctcaaat
     1621 aagcctcttc gtcatctgat tctggtcttt gcttgtgatt gacatgcgca atgccaatcc
     1681 gaatttgcaa ttttgcttga aaagcatgca aaaagtgcag caaattcatc gaatctactc
     1741 caccagatac agctatcaaa acagcctgat gagcgtcaaa ataggccttc ttttttatga
     1801 tgttataaat gtgttgataa gtcattttaa aatcgaataa acatcgtcag caattgctgt
     1861 gatgtcgtca taggaagcct tatctgtaaa aacggataag ataaagggat tatcaccata
     1921 aacaatggca acatcatgct tgtaatcgta ggcgtctcca atcttgtgag ccactggcac
     1981 agaaatattt tttgaaatgc gctgatcatc aaatgccgtc tgtgacaaat aagaaataat
     2041 ctgacctttt tgataataga tagcttccat gagatttgct gctgcatgag aagaaagcaa
     2101 gcgcttttcc atgtcccaat ctactccagc taaagcccta atctctgatt gaaaggcttg
     2161 attatattga ttacataggt agtagcctaa gatattagta gcaacattgt cagactgctg
     2221 agccacagcc tttaaaagct ccatcacatt atagtccttt ttgtcagctg ttttactgat
     2281 tttaccactg ccagttggat cgtaatcacc ataaaaatga ttgacctcat caatgtattt
     2341 taagctctta ccttcagata agctacctga cttcagtttt ttttgaacac tgtacagggt
     2401 tgctaatttg gaaatacttg ccgcatacat ctgtttatca gcattgatac ctgcactggc
     2461 ctgcgtgtta agctgcttta caaaaataga ataattctct ttattatatt tttgcaatag
     2521 catttcctga accttcaaca tgcgattgtc ggtaggtgac aactcctttt gattaaccca
     2581 gcccttatga tcaatgaaat aataggtccc atgctctgtt tgagccatct tactagcatg
     2641 aacctttctg ccaggctcac tatctgatgc aattgtctta acacctaaaa catagggttc
     2701 agcatatata gtcatctttt tttgagtcca aaaatccaaa tccacagctg tctgctcaaa
     2761 cataatatcc tcgtaaacaa tctgacgact agcttcaagg taagtgtcat ctgccagtct
     2821 aaagacagga atagctgcct tgtttagcaa aacatccttg ataacaattc tattgtctgg
     2881 tgcgatcatc gtctttggca cactcaattc gggatcccta taagcaactg tctcctcaaa
     2941 aacattggga ttagtcggaa tccgactata ataaagagtg gagctaacaa tatcctgact
     3001 taagtgatag cgtgtcgctt cagaaaacac tgggattttt tctgtactaa tgaccgttaa
     3061 aggagtcacg aaaaatgtca ttaacatagc tgctaataat tttttcacaa tggctccttc
     3121 ctattttact tctgtgcgat gatggtcttt cttcagctct tgattttcct tttctagctc
     3181 tgctaatttg tcatcagaaa aggcaagaaa ggtttcaatt ttttcgacaa tattatccat
     3241 agtcaattac tattttggta ataatccagg agttggataa ataacctctc cttctcttga
     3301 taagtaatat ttagccctag catacttttt gacaaaatca tcatttttta gctgctcagc
     3361 taactgcttt tcagacttag tctttttttc taactcacga tactcttttt ccaacgtaat
     3421 aatctgctga ccttgttttt tcagtgaaac ataaccctta accaagttat aggttggcag
     3481 aataaacaag aacatcatac taaccaagat ccaacccata aaacggttcc gtttttggat
     3541 ttcctcttcc tcaaaccgtt ttttgatatt ttcttcgttg atataatggt tattcaactg
     3601 gacgatacta ggcttcttca tcgctactta tccttgtttc gctgataatg tcatacattt
     3661 tagcagcgtc ctctttttta gtgctatcct tcatatcaag cacacgaaca gtaagcaact
     3721 tattgccaaa cctgatttca acctgatcat ttagttttaa atcagttgag cttttcgcaa
     3781 ggataccatt aaccttaata cgtcccttat ctgcgacttc tttggccact gatcgacgct
     3841 taatcaatct tgataccttt aaatatttat ctaatctcat atcttttgcc tcacaatccc
     3901 tttcattcta tcatttttct ttgacaaatg gtagaaaaga ccacaatttc tctttaaaga
     3961 cacctagctt tttgcaagct attaaaaaag aggataaacc aacagcagat gacaccaaaa
     4021 gactaatcag cgcaccaagt cgacctgata atggcaagca atactgactt gtaagcacac
     4081 acatgagcat gatcactaaa gcaagcccat atttagcatt cactatcgct ttaaaatcaa
     4141 tatcagccag cacagcatac aagagtaaaa cgaccagcaa ggggattagg gtggataagg
     4201 agcttccaac aatagcgtaa tagtaggtta atataggtgt taagcctaat tttaataaaa
     4261 agccaaacag caaaataagc aaagattgct tgatgtgatc ctcaatgaag catttttgat
     4321 gaaagaattg aatcatgctt gatactgcta taatcatcag gtaaaccact aaggccagcc
     4381 agcccttatt gtcctcaaat aaggctcgat tcatcagatg gagaatacta ataaaaccaa
     4441 cagtcagtgt taaactaaaa taaaagataa actcaaagaa acattgactt tgctctctat
     4501 aggactccct tttaatatga aacaagactg ttaaattcgg taaataagct gtaaataagg
     4561 ccgtcgaaaa aatgagacca aattgcagca agggctgtcc cctatcgtaa acacccttag
     4621 tcatttcagc tgttatctct gataagcctg agctaaccaa aatatttttc accaaaagag
     4681 aatctatcaa ttgaaaaaca agcaggtaaa ttgaaaaaag taaaaaaact aaggtcggca
     4741 agcccagact tgttaaatct ctaatagcaa ccgtatctcc tgataaaaag ctttttaatg
     4801 aataagcact atgacgcttc aaataagcta aaataactaa gctcgctact aaatttccaa
     4861 aagcagcaac atttgctgtt aaataaaccg tccaaccaag caccctgtag catagtgcag
     4921 caacaatgat tatagcaact cttatgatct gctcaagaac ctgactcaga gctgtaggag
     4981 ccatattcat atcagcctgg gctaagcctc tgtaaaagga tataaagggt actattaaca
     5041 aaaccattgc tgttataaca attgatggtg ccaactgctg tgctcccatc cagctagcca
     5101 atgccttatg acttagcacc aatattcctg acaataagaa gctggtatag cattgcaact
     5161 taaatagagc tgctagctgt agctgctttt ttttctgggc catactggca atcacattgg
     5221 gtaaagcagt tagacctaag gctgaaataa tacctagcaa aggatagatt tgttggtaag
     5281 cataaaagcc cctatcccct accaaatttt gataagggat acggtaactg gctgctaata
     5341 attttgacat aaaaccacta ataacaatca gaagacttga ttgcttagtt ttatgaggaa
     5401 gcttttctag atttaatctc accaagtgtc tctccaaaaa gtatcaattc ttctaaaatg
     5461 acatggtctt tctgacgtct aacatcaaag ataatttcaa ttttaccctg atgctcacta
     5521 atccttgctt ttaagcttgt ttttgacaga gcctcaaaat aatcctgtgt caaatagtat
     5581 tgaagcgaag caacctcaaa cctaaccata acctgatggt ccctcttctc gactaattca
     5641 gcaaaggctg tatccaagta gtatttcaac aagccaatct ccagtaaata ggctacctga
     5701 tcaggatagt caccaaaacg atccatgatt tcatcttgca aatcagaata agctgctcta
     5761 gagtcaatct cacgaatgcg cttataaatg tcaatttttt gacgctcgtc tttgatataa
     5821 tcactaggta aataagcatc aatatgcaga ttaatctctg cattaccttt ttgtcgcgtc
     5881 aatgctcttc cttgcttgct tgcaatagcc tgctccagca gctgagaata catgtcaaaa
     5941 ccaactgagt caataaaacc actttgtgaa gcacccaata tatttcctgc tccccgaata
     6001 gataaatctc gcatagcaat tttaaagcca gatcccagct ctgtaaagcc cttaatagct
     6061 tctaaccttt tttcggaaac ctctgttagt accttatcag gcttatacat gagataagca
     6121 taggcaatac gattgctcct tccaacacga cctcgaagct gatacaaagt tgatagtccc
     6181 atatgatcag cattttcaat aaataaggta ttgacattag aaatatcaac ccctgtctca
     6241 ataatagttg ttgcaactaa aacatcataa tcaccattga taaaatccat caaggtattc
     6301 tcaagctgaa tgtcactcat ttgaccatgg acaaaaccaa tagaagcctc tggaaccaat
     6361 tcttgcagct ctgccacctt cttgtcaaca gtgtcaacct tattgtaaac ataaaagact
     6421 tgaccaccac gatccatttc tcgaataata gcttccctaa tcaagccagg attattttct
     6481 aaaacataag tctgaacagg atagcgattc gtaggaggcg tctcaatcac tgataaatcc
     6541 cgaataccaa gcatagacat atgcagggta cgaggaatag gcgttgcagt cagtgtaagg
     6601 acatcaacct tggtctttaa ttcctttagg gtttctttat gcttaacgcc aaaacgctgc
     6661 tcttcatcaa tgacaatcaa gcctaaatct gaaaaaatca catcctttga cagcaaccta
     6721 tgagtcccaa taataatatc aacctgaccc ttttttagcc tttctagact ttcagattgc
     6781 tcttttttac tgcgaaagcg gcttaaaaca gcaatttcaa ccggatagtt ctcaaatctt
     6841 tccctaaaat tctcataatg ctgctgtgct aaaacggttg ttggtactaa gatagctacc
     6901 tgcttatggt caccgatagc cttaaaagca gctctcatag ccacctcagt cttaccaaag
     6961 ccaacatcac caactagtaa acgatccata ggtctgacac tctccatgtc ttttttaacc
     7021 tcttttatgg acctaacttg atcatcagtc tcaacaaagg caaaatcctc ctcaaatgct
     7081 ctttgtaact catcatctgg agaaaactga aatccttttt gctgactccg ctctgcataa
     7141 agcttcaaca ggtcatctgc aatatcctca acttgctttt taaccctttg ctttgctttt
     7201 tgaaaacgac catcgtttag tttattaatc tttggctctt taccatctgc tgatacatat
     7261 tttgataagc tttcaagctg atcaacaggc aaagaaattc gatctgactg ctgatactga
     7321 atggtgacat aatctcgatg taccccttgt atgttaatcg tttcaatgcc taaaaaacga
     7381 ccaatcccat gcacactgtg gaccacataa tcacccttag acaattcatt gtaatccttt
     7441 aagcgttcag cattactcat attagtacga cgagcacgac gcttcagcct cttatgatat
     7501 atctcatgct cagtaattaa aactaatttt tcatcagcaa agtaaaaccc acctgctagg
     7561 tgaccaataa tgatttgtgc ttgatgtaat actattgcat cagcagaaac aaggggcaat
     7621 tgacattgat aagcctcaag agattttgcc aaccgctcat aagcttgatg agattcaacc
     7681 tgtaaaagga cagttgctcc agatttttga taccgcttaa tctcatcaat gagcagtgga
     7741 aattgattga aaaattcctg catggcatac tgtgttaagc tatacacctt atcaaattta
     7801 atattaccaa gtcccttgtg aaaatttgaa aagaaggtgg caggcttata gtgtcgcagc
     7861 tcacgataat tgtcagcaaa ataatggaga aatggaagtg actttccttg ctgtaaatca
     7921 tctgtcaaca aatgagcaag ctctaagtca aatttagcat ttctgtcaac taacttttgg
     7981 aaatcatcaa aaaatactgg tgttccctta ggaaggtaat ctagaatcgt ccattcatta
     8041 tcataaaaca gtgattgaaa tttacggatg tccttatgct tcaggccttc ttttgttaca
     8101 gtgagcaact cctccagata gcctttatgt tctgccttag caagttgaag ctgcttttca
     8161 agattatgac tagccctatc aaaatcctcc ggctcaaaaa tcatatcact tgcaggcttg
     8221 atactggtgc tatccttctt ttggagagat ttttgacttt ctatatcaaa gctcctaata
     8281 ccatcaatct catcaccaaa aaattcgatg cgaacaggta agtcctgtgt tacctcgtaa
     8341 acatctaaaa tatcacctcg tctgctaaat tcaccaggac taaggacctg agccaccctt
     8401 tgataaccaa ttttgacaag cttcttgaca acgttgtcaa gatcagtgtc aactcctact
     8461 gctaagtcaa tctgcccctg ctgaaaagtc ttaggacttg gaagtaggat tctgagtcct
     8521 gctaagctaa tgaccaatat tcctcttgct tctggatttg ataaaaaagc tagtgcctct
     8581 attctcgaga ttgttttatc catagaggag aaaataaact cagccgcagc agtatcatct
     8641 gcaaaaaatt gaaaaataga gccctcatca agcaaggctg acaaatcacc agctaatttt
     8701 tccatgtcat tttgagttga tgtcaccacg accagcttcc cttgaaagct aagataggct
     8761 gaggcaatgg ctgctgcttt acttgagcct gacaagccca tgactaattg ccgttttaag
     8821 cttgttacat cacattgcca ggtctggatt gacttgtttt gattaaataa ttctaaaata
     8881 tccataacta cccattaaat tgctgcattg ttttctcaat gcttttttcc tgtaaataat
     8941 agttgattgc tttgtcaacc ttatcaagtg ctatattgat tgttatcata tcatctgtat
     9001 caaattttcc tagaacatga ttaataacac tcattccatg acttggtctt ccaataccaa
     9061 ttttaaccct atcaaattcc tgtgtaccga tatgagcaat aatggatttt ataccattat
     9121 gtccccctgc agagcctttt tgacgcaaac gaattttacc aactgccata tctaaatcat
     9181 catagatgac cattaaatct ttagttgaaa tattgtaata ggtcaataaa gccctaacag
     9241 caagaccact attattcata aaggtagttg gcttaacaaa ataaatcttt tcttgattga
     9301 taaaagtact cccaataagg gctttgaagg ttttatcttc tgtaaagcta acgtcaagat
     9361 ccttgacaag tctgtcaact gccataaaac caacattatg ctttgtttgc tgatgttttg
     9421 agcctggatt tcctaatcct acaatcattt ttaccatact aatacaccag agaaacgagg
     9481 tatgatagca gcctgttgac cattcttaaa gctttatcag cctcttcccc tctatttttt
     9541 gtcctttcta agcttttgat aggcaccaaa agggctggaa tactatccca accctagaac
     9601 acaatattgt taccactaaa cattgaatct aaattccata atatcgccat cctgaacgat
     9661 atattccttt ccttcctcac gcagacgacc tgcctcttta acagcctttt ctgagccata
     9721 cttaatcaaa tcatcatagc tcatcgtcac cgcacgaata aaaccgcgct caaaatctga
     9781 gtgaatgata ccagctgctt gtggtgcctt aataccgcgc ttgaaggtcc atgcacgcac
     9841 ttccttttca ccagctgtaa agtaggtgcc aagtccaagt aaatgatagg ctgcacgtgt
     9901 cagcttgtca acgccagatt ctgtcagacc gatagcttct aaaaattcac tcctgtcttc
     9961 atcatctaac tctgaaatct cttcttctgc acgagctgaa atcacaacaa cctctgcatt
    10021 ttcagttgct gcaaagtcac gaatctgctt cacataatca atagcgtctg gaattgctac
    10081 cttatcctca tcaacgtttg ccacataaag cactggctta gtcgttaata aaaataactg
    10141 cctaacaatt ttttgctcat catctgtaaa gctaatggta cgagcagatt tgccttcttc
    10201 aagcactggc ttaatttttt caaggacagc aaattctgct acagaatcct tgtccttttg
    10261 tgtacgggcc attttttcga cacgcgcata gcgtttattg attgattcta agtcagccaa
    10321 aattaattca aggttaatcg tatcaatatc tgccaaagga tccacaaagg catcctcacg
    10381 cccctgctca cgcatgacat tttcatcatc aaaggcacga accacatgaa caatagcatc
    10441 aacctcgcgg atattggcta agaacttatt tccaagtcct tctccttttg aagctccctt
    10501 tacaatacct gcgatatctg taaattcaaa ggttgtaggt actgtttttt taggcgtgat
    10561 aagctctgtc aacttctgta aacgctcatc tggaacctct accataccaa cattaggatc
    10621 aattgtcgca aaaggataat tagcagcctc tgcccctgct tttgtaattg cgttaaataa
    10681 ggttgatttc ccaacgtttg gcaaaccaac gatgcctgct gttaaagcca tatttttttc
    10741 ggtctccgtt acattttttc aatccttatc attatagcaa aaaaaagaag aaaaagcttg
    10801 cctagtaatg atctttaact aaaatggatc acaataaaat acacacctaa caaaacgatc
    10861 acaaccaata atagcataag aagatcgcct ttacgcattg gccgcttaga ttcctcagtt
    10921 aaaaattccc atacgttcat tggcttttca gttttcttaa taaccttgat tgcaggttct
    10981 tttccagtca ccaattcatc taaagttacc tctaaaacag ctgccaatgt aactaaattt
    11041 tccaaatccg gtgtcgcatc tccattttcc cactttgaaa tagcctgacg ggagatgaaa
    11101 agcttctcag ctaaggcatc ctgagacaac tgcttttcaa gccgatactt ctttaattgt
    11161 tctgcaaatt tagtcatcat taatgaccgc ctttcctttt tgatagcttt acaataactc
    11221 ttttttaaaa ggcaagctag caatttttaa cgcaataatg agttgcgaag gtagttaaaa
    11281 accttatgac aatagagctt ctatggttgc agaaccttct tcattttacg ctcaaaatca
    11341 tgacgactta gcatgataac atgattacag ttagtgcatt gcagcttaat atctgctcct
    11401 actcttgtga ttttccattg atttgccttt tttcctgttt ctttaatgac acaggcatgg
    11461 ggctttttca tttcaattaa ggatccaact tgatacatca ctttatcact cactcatctc
    11521 ttatatttat tatttatcat aacaaaaaaa gcccccaaaa gggagcgttt ttcgcttagt
    11581 ttgtacgaac tggtgtgatt aattgaataa agctctcttc atcatctccc ggtgttaagg
    11641 tgaaaggacg aacaggcgat aggaagtgaa tcttaaccgt ctcactttta atggctttta
    11701 aggcttcaat cagataggtt gggttaaagc taatggttaa atcattccct gcttgactca
    11761 ccacgtccag atcctcgtta accttaccaa cctctggaga gttaacatga gctgaaatgc
    11821 gatttgcttc aatttcaagc ttaacagtac cattttgcgt agcgtttgaa atcaagaaag
    11881 cacgctccat agcatgtcgt aaggattgtg tgttaaaaac agcctctgtc tcaaactgct
    11941 tcatcagcaa acgatcagta tcagggtaat taccttctaa cagacgggtg taaaaagaaa
    12001 tgtagtcact tctaaatagc atttgactag cagaaaagaa cacttcaacg gtttctatat
    12061 catctgtaaa gacagctgaa aattctctca aggatttact tggaataacc acatcaaaat
    12121 cagctgaggt tttctccaga gtaatcaagc gctggctcat acgatgtgaa tctgttgcca
    12181 ccgctttaaa gttcttatgc tgacttaggg tgatgtgtac gcctgtcaaa ataggacgac
    12241 tttcctgcat actagcagca aaggctgtct cagcaatgat agattttaag agtcttgtat
    12301 ttaaaattaa aggattttca gttgatacct cttgaagacg tgggtattga gaaacatcct
    12361 tcccctttaa ggtgatttca gatttcccac tggttagcac cacctgatgc tgttcaattt
    12421 ccttaaattc taagctaaca tctggaagac ttgagataat attgataaaa aagctggctt
    12481 ctaaaagaac agcccctgtt gaggttatca acaagcctgc gttttcattg ctaacaggaa
    12541 tggtattttc aatagagatt tgaccattag agccagtcag ggtaatgtct gatggattaa
    12601 cctcaatctt gatggttgat aagatcggta tagcattttt actgctgata gcccttttag
    12661 tggctgttaa agcttgaatg aaaagggctc tattgataga aaattgaatc atggtaactc
    12721 ctttgttata taagtattat agctagtagt agtagtaggt cttgttaaaa tagtggataa
    12781 gtctccttgt actagtcgtt actagttaaa acgcttgtgc acaagctgtg gataaatttt
    12841 cctttttgct aaaggttatc cacattgctt atttgatttt gttcttgatg gtttcaattt
    12901 caattctgag gctctcgtct tgtccaatca tgtttttaat tttgttataa gcatgaagca
    12961 cagttgaatg atcacgtcct ccaaattctt taccgatctt tggcagactg ttatcggtca
    13021 tctcacgagc taaaaacata gcaacctgtc tagcaagcac gatatcctgt gtgcgtttgg
    13081 tcgccttgat ttccttaacc gtaaccccat aaaattttcc aacctgagct tggatttctt
    13141 caattggaat gacagtcatc ttaggaccgt cttgctttct agctcgaata gcttctgctg
    13201 ctatgtctac tgtaattgta tcaatttgtt taaaattagc cacaagacta atatccttca
    13261 aagccccttc caggtctctg acattagagt caaattgacc ggccaaatat tcgatggtgt
    13321 cctgaggaaa gatgaaatta tattcttgaa ttttattggt caaaatagca acacgtgtct
    13381 caaaatcagg cggtgtgata ttaactgtta gtccccactt aaatcgagtt actaggcgat
    13441 cttctaggtc attgaggtga tcaggggttc ggtcacttgt taaaacaatt tgcttgttat
    13501 tgttatgtag agcattgaag gtgttaaaga actcctcttg tgtaccagac aaggtttttt
    13561 tagctaggga ttgaatgtca tcaattagga ggagatcaag attgcgaaat ttctccttta
    13621 gctcgtccat agtatctaga cgaatatgaa caacaaattc attaataaaa ttttcagccg
    13681 taatgtattt aatcctagca tttggatttt ccagtaaaac tgaatttcca atagcattta
    13741 aaagatgggt cttaccaaga cctggacctc cccagataaa taaaggatta taggttgttc
    13801 ctggtgtatt agctaccgct attgatgcag caacagccca cctattttca tcaccttgga
    13861 taaagttgtc aaagctgtat ttagggttta gatcggactg tactgctggt aattgctgga
    13921 aggcttgttc agtatatcct tgctgtccct gatgctgttg ctcaatcatc aagtcatcct
    13981 catagacata gtctacagca atttgagcat tgtaaacttc aaatcctgct gttaggataa
    14041 cgtctttgag atttttttcc caaaacaatt ccttcatctg atctaaaaaa attgttgcga
    14101 catgattgtc taccttgatc aaacgagcat catgaacaaa aaattcataa gttgcctgct
    14161 ttaactggct ttgagctagc tctaagaccc tattccaaaa aatttgttca ttttcagtca
    14221 tacgagattc cttcttgtgg ataattctag aaccattcta tcataaataa agatagtttt
    14281 ccacaaagga tcaaggatta ttttagactt acccacaagc tgtggagata aaatacacaa
    14341 tgtgtaagat agttttccac aacttgtgga aaaaagagaa agccttgtga taaaaggttt
    14401 tagccccatt tctcttgtgg aaaactgaat aaaaaaaaca gacaatcaac aagctaaagc
    14461 aacttgttga taattctgtt caattcttct tggtttgaaa atgacagttg cagctgccca
    14521 ctgtcatttt tttggagaga caatgccaca ggtaatccta atgattttga gagctctttt
    14581 tctaaagact tcacaaaaat ggttttatgt ttgtttcttt tttttggggg atgcttagtc
    14641 tttaccagct gttcgatttg cctaacgctt aagccttgat ccagaatgtt gtgaaaataa
    14701 agctcctgct cttttggtgt tgacaaggat aataaagctc ttgcatggcc ggcgctaatg
    14761 gtaccgtcct caatcgcttg tctaataacg tctggtaatt gcagcagtct gatggtgttg
    14821 ctgatataag ggcgtgattt tcccatgtat gtcgcgatgt cctcatgggt catcttattt
    14881 ttatcaataa gtaattgata ggccttagcc tcttcaatag catttaaatt tgagcgctgt
    14941 aggttttcta cgatggcctg ctgcatgctc tcaagagtag agatttcctt aacaattgct
    15001 ggaatctttt gaagtcctgc cagcttggct gctttaaagc gtcgttctcc agcgactaat
    15061 tcatagccaa atacatcaga ttttctgaca atgattggtt gaatcaaacc attagcctga
    15121 atggaatgtg ccagctcttc aagctctttt tgattaaatt gaagacgtgg ttgataagga
    15181 tttgccacaa tatcctcgat aggaatgtgc attaggattt ctgtcatata agcctctcaa
    15241 aagggaaata gtggtagctt aacggttatt agagatacat acgggataaa agagcaagag
    15301 cccgcgacca tcgtctcgga ctcaatctca cggggatacc caatgtttac tgctttttag
    15361 ttagatcctt agttgttttt gttaatttga tgtcaacttt cttcttagca gttcctctgt
    15421 agaaggttac cttaatggtg tcgttaatct catgactata taagacactt tgtaggtcac
    15481 taattgagct gacttcttta ccgtcaacct cagtaatgac atcatactgc tccaatttac
    15541 caagagcagg catgccatct tgagtagagg ctacgacaac accgctggta acgcttgttg
    15601 gaatattcaa ttgaatcaat gcattggttg atagattact taagtttacc attgtaatgc
    15661 ctaaggctgg tctgataaca gctccgttag actctagttg gttaataatg gtgacaacat
    15721 cgcttgatgg aatagcaaag ccaattccct caatggctcc gccgctacca gtaggtgttg
    15781 aggatatttt acttgagttg ataccaataa cctggccttc aatattgatg agtggtccac
    15841 ctgaattacc tggattgata gcagcatcag tttggatagc atttgttgag atggtctcgc
    15901 ctgcctcatt tcttgaagtg actgtacggc ttagacttga aacaatccct tctgtcactg
    15961 agttggcata ttttgttcca agaggactac caattgcaat ggctacctct ccaacattaa
    16021 ttttggttga atctgcaaat ttggctattg ttttgatttt atcagcagca actttgacaa
    16081 cagctaggtc agaataagtg tctgcaccaa ctagttctcc aacgatctta gagccgtctg
    16141 ctgttaaaat ttcaattcgt tgagctccct caataacatg attgttggtt acaagataag
    16201 cagtattacc ttcttttttg tagacaacac ccgaaccttc actgtgtatg cttagctcgt
    16261 cctctttttg tactgctgag gtatcatttt cttctccgaa aagattgatg taaggatttg
    16321 aaatggcagg cgaagcagcc ttttgatagt taataacaga cactacagca tcttgaacca
    16381 ccttaacagc ctttgttgta tcagttgtat tattaaagct gacgttgctt gttgtcgttg
    16441 ctccctttgc atttgaagat gttagagaat tctgactaaa tccattaaca actaaggcag
    16501 ctaataagcc ccctaaaaat ccaatggcta aaacccataa gggcttcaat atattttttg
    16561 attttaacac aaaatcacct ccgaatggtt ttcacatagg atataaaacc tcacttaatt
    16621 ataccttaaa accataaaaa agaaaagtaa tccacaactt gtggaaaact tttcaggact
    16681 atactaaaaa ggctgtagaa aagggtttat ataaagaaaa taagaaatca acatgtggat
    16741 aagttgtgta aaaagagttg attatggtac aataaggata tgaaaataaa gcttatttgt
    16801 gtcggaaaat taaaagaagc gtatttaaga gatgggattg cagaatacca aaaaagactg
    16861 tctcgctttt gccaatgtga tatcattgaa ttagcagatg aaaaaacacc tgataaggct
    16921 agccatgctg aaaaacagca gattatggct aaggaggctg acaggatcaa gaaaaagctt
    16981 ggtcagcgtg attttgtaat tgctttggca atagagggca agcaattggc atcagaacag
    17041 tttagtcatc tactatcaga ggtcactgta aaaggctatt cagacattgc ctttgtcatt
    17101 ggtgggagtc ttggtttgga tcaatccatt aaaaataggg ctaatttatt gatgagcttt
    17161 ggcctattga ccttacctca tcaattgatg cgtttggttt taatcgagca ggtttatcgt
    17221 gcttttatga ttcaacaagg cagtccatat cataaatagc agttgtttca catgaaacac
    17281 tacacatggc atagaagaag cgcgtgtata cctcaaccat acttctagct ttcattaata
    17341 gggctgttga tttgcagcct tactcagcta ttgcctgatg ataaaagcat taattgcttt
    17401 atcgaactga tgatttggag gttttgtgat tttagcctta gacgatgtca ggcaaatgct
    17461 tatcactctt atgactctcc tacgggagtc agtagcttac tattgttaga aatacaaaaa
    17521 gccattagat actgactaat ggcttttttt actatttctg atctcagcag gattcgaacc
    17581 tgcgaccgtt cgcttagaag gcgaatgctc tatccagctg agctatgaga cctcaaccac
    17641 cttattttaa caaaaaaacc ttatgcctgt caatgcttat ttttgataag aagcttcact
    17701 gccctaaacg tgcggtgata tgtcttttag cagtttgtat cagaggagca atgtgttatg
    17761 ttttctagca tgtttggggt aattagactt gttttagact gtttatgtca aaagtgatca
    17821 aaaaatcaag atttttttga aaaaagtata gacaaataaa aacattctgc tataataata
    17881 agagtgttaa ggagagttac tcctgaactt caggtccgtt ggtcaagggg ttaagacacc
    17941 gccttttcac ggcggtaaca cgggttcgaa tcccgtacgg actatcagaa ttgtctttgt
    18001 ggcaattttt ttattttccg gcatagctca gttggtagta gcgcatgact gttaatcatg
    18061 atgtcgtagg ttcgagtcct actgccggag tgataagaca cttcctaagg ctttcttagg
    18121 atttttttat tgaccttgaa gagtgattgt gatttgctaa gaaacttaaa aatacgctaa
    18181 tcgtctaaat gataggcttc tcttttttgg gactaaggaa cacgtgagtt atggaaagtc
    18241 atgtgttttg ataaatatcc ttaaatcaat agaccagcta aaaacacttg attttgatac
    18301 ctggaagggc tgtaaaatca agcgttttgc ttatatatgg aaattgctgt ttaagctttt
    18361 agcttggctg tttgcctgag taagtagtaa tgtaagaagc tgtaaagcaa gataccaata
    18421 aatgagagca gtaagcctaa tgtaaagcca tttggaacaa aggtgagtac taatttacca
    18481 gatccttttg gaacatctat cctaataaaa ccaccttgag cctttttaag agccactggt
    18541 cggccattta gtcttgctgt ccagcctttg tcatagggaa gggtaaaaat catagagcct
    18601 tctgatttgg ccttgtaatg gctaatgacc tgattgctac gggtgtaagt agtaacctct
    18661 ttttggttaa tcgcattcat ggctgccaga tagttgtcac tatttaaact gtagaagtgt
    18721 ggggtagcaa aggaaatatt tttgtttttc ggaaacataa tagcaagggt taaggttctt
    18781 cctttttcaa agtaccctaa gtcaaagaat gaaaaagcgt tgtcagtagt gtactcgtag
    18841 gtctgatcat caatacggat cctaacagct gttgcattgt gatttgaaaa gctaatattt
    18901 ggaagactta agtagagctg cctatggttt ggtacagtaa cctgataatg aacaatggtt
    18961 gttgacgtat tctcagcagc ctcccctgaa attctcccat taaatacctg agcatttgat
    19021 attagcttag aaggctctag ctgaaaatag gtgagccttt ttccactcag ctgattcagc
    19081 agcttggttt gattgtcaag tgtgttgaca gttaacttga catctttgta aatgttatct
    19141 gttaagatag ctagattgct gctatagtga ttttgataga gtgtagtgtg atgactggag
    19201 gctatccttg aaaagccaaa tttatgaagc tgatggtagc taagattgta ttttatccct
    19261 aaaagactat ccatgatgag agtgttgttt tgatagcgaa ggtttagatt tgttccagca
    19321 gactggtagc ctagacgatc cagaagggag ctggagtgac gatttcggat agatgaaaat
    19381 tgagaaatgc cattatagct gtatttcata ctatcattgc ctgtttgtgg taggagctgc
    19441 tccagtctga aaaactgatc attgctatca gctgttttct tgacaagtct gtcaatatcc
    19501 tgtaaagctc tactatagcc cttacgtgat ggaaacaccc attcatgatg aatgccatta
    19561 agctgataat aggtatttaa actggtttct aaacagctaa acagtagggt aaaaaagatt
    19621 aaaaatggca ttggtacaga ggttttttgc atgcttaaca ataaaataag atatgccgct
    19681 aaaaaggcaa gacttaagat caataaacta ggctgtaaaa agctatactg atccattgtc
    19741 agataaggaa gtgttaataa gcagcttaat aatataaagg caaagattat tctagtgtta
    19801 gtaatgtctt tttgtctaga aagggcttcg caggctaaaa taatgataat gattgaaaat
    19861 gaccacgaat agcggtgcaa aaacatattg ggtccatgca tgccctgcca aaataaatct
    19921 aagggctgaa gataaaagct agccatgatg agtcctaaaa gcagcccata gcccagtctt
    19981 aagcgccagc taatagattt taaggtgaaa aagacgatac ttaacaatga aggcaacaga
    20041 ccaataaata tcatgggaat cgcattaaac tttgtcgtat cataggcacc aagtgatagc
    20101 tttgctaata aatcaaaggc tcctataggc ttaatgataa tctgattgat tggagagagt
    20161 gtttcaccgt aggctgttag gtctagatag gccggtatga gtataaaagc acttgttaag
    20221 gctgataaga ttgacactga tgtaaagctt aaacaggctc ttaaccgtct tttccatgtg
    20281 tctagtgata taaggttgac tagaaataat aaaaaaataa agatagcaac catatatcca
    20341 aaataataat gctggataaa gagaagacta agtgagctat aataaagcaa gggcttggtt
    20401 tgagtaatca gccgatagag ccccagtaag acaattggta gaagaataaa aacatctaac
    20461 cagttgttaa gctctagctg gcttgtcaga aagctcatta gggagtaaga gactgataat
    20521 gtcaggacta aaaagggttt gattttaggg taaatacgat gaaaggagaa ataagcggca
    20581 agcccgatca aaccaaattt aataagtgtc aagagataga tagcatctgg catggattgc
    20641 agattaaaaa aatagacaag aggagacaaa aggctgccta gataatagct agccagagca
    20701 aaaaagttta cacctaggcc actggtaaag gtgtaaaaaa tactatcagc cccatgaaga
    20761 atatttctta gggcttgcgc aaaaataaca tattgatgaa agccatcact agctaaaatg
    20821 gttttctcac tgccatatga aattcccatt gacaaaagaa caaaaaacat tatcaaaaag
    20881 ggaaggagga agctagcaat gtcataaaca agagaccatg ctttaggttt tgtcataaat
    20941 aagcccttct atgatatttt tgaaaaaaga gctagaaata gtttccagcc ctcagatgtc
    21001 atcggtgatc atctctatac tttaatgatg atattgagca aagctccttg tttcttcctt
    21061 atttccaaag ctctgctacc ttagcttgaa cgtctttgtt ttcaaggaat tcatcatagg
    21121 tttcgtcaat acggtcaatc acaccatttt tagaaataac aacaatgtga ttagcaatgg
    21181 tttggataaa ctcgtggtcg tgactggtaa aaataacaga ctctttaaaa tctttaatcc
    21241 cgtcattgag acttgaaata gattccaaat ctaggtgatt ggttgggtca tcaagaagga
    21301 gaacatttga ttttaaaagc attaactttg atagcatcac gcgcaccttc tcaccaccag
    21361 agagaacgtt aacggatttt ttaacctcat ctccagaaaa gagcatacgt cctaagaaac
    21421 cacgcaagaa ggtatcatca tcttcaccct ttgctgcaaa ttggcggagc cattcaagga
    21481 tagactcatc gctagcaaag tcacgtgagt tgtcctttgg cagataggag cgactagttg
    21541 ttactcccca tttgatagtc ccttcatagt caatgtcatc agccagagcg cgcataagag
    21601 ctgttgtttg aatgtcattt tgtccgataa tggcagtctt atcacctggc cttagaatga
    21661 agctaatgtt atctagaatt ttgtcaccat caacggttac agacaaattt tcaactgtta
    21721 caaagtcatt gcccatttca cgctcagctt taaaattgat gaatgggtat ttacggctag
    21781 atggaataat ctcttctagc tcaattttgt ccagcatttt cttacgagag gttgcttgct
    21841 ttgatttaga agcattggca gaaaagcgtg ctacaaattc ttgcagctct ttgatttttt
    21901 cttcggcctt agcattacga tctgcctgaa ggcgtgcagc taattcagat gattgcttcc
    21961 agaaatcgta gttaccgaca aaaagcttaa tctttccaaa atcaaggtcg gccatgtgag
    22021 tacatacctt gttcaaaaag tgacggtcat gtgacaccac aataacagta ttttcaaagt
    22081 caatcaagaa gtcttctaac catgaaatag actgaatatc aagaccgttg gttggctcgt
    22141 ctagcagcaa aacatcaggc ttgccaaaaa gtgctttagc taggagaacc ttcaccttat
    22201 caccattggt gagctcgctc atgctttgat aatgcaattc ctcagggata tttaggtttt
    22261 gtagtaattg agaggcctca ctttcagcct cccagccgcc tagctcagca aagcttcctt
    22321 ctaattcggc agcgcgaaca ccatcttcct cagaaaaatc aggcttcatg taaatagcat
    22381 ccttttcctt catgatactg taaagctgtt catttcccat gataaccaca tcaatggcac
    22441 gttcctcttc gtaatcaaaa tgattttggc gaaggacaga aagacgctca tctggtccta
    22501 aagagatatg acctgttgtt ggttcgatat cacctgcgag aatttttagg aaggttgatt
    22561 ttccggcacc attggcacca attaagccat aagtgttgcc agctgtaaat ttgatattaa
    22621 catcgtcaaa aagttttcga tcactaaagc gcagtgatac gtcagaaact gttagcaatt
    22681 tgtcacctca ttttatttat ctaatcctca ttgtacctaa aaaagcccct tttttcaatc
    22741 agaaaagggc ttagggctta cataggcagc agcacatctt tgtcctctag tttgtaatgc
    22801 ttggttaagc tgaagccacg tcccatgacc tgtgctgctg gcatgacaac gataaaggca
    22861 gtgtcatcga tttctagaat tttttcctgt aaagctggca actcatagcc agaaacaatg
    22921 gccattagca tgatcttgtc tgatgttgtg tagcctcctc ggataggaat cttagagaca
    22981 ccacgatcca taacacctgt aatataagcc ttgatggcct gatattcctt tgaaataatc
    23041 atgacattct tagaagagtc aaagccattt tccatgacac taatgacata gccaataacg
    23101 agcagtccga tcgtagaata catgacatca tcagcagata aagcgatgaa tcccattaaa
    23161 acactaatgc catccacaat agtcatagca actcccaatg ataatggaga atatttgtgt
    23221 aggatttgtg tcagaatacc agtacctccg gttgatgaat ttccccaaaa gaccattcca
    23281 aggccgatcc cacaaatgat gccaccaaaa atagctgcta ataattggtt atgagtgagt
    23341 gttggaagct ggctggttag gcgtatagca atagggtaaa tccatgaacc gtagagggtt
    23401 ttgatgagat tttgtttacc aagaaagaag tagcataaaa tcaataaagg gatattgctt
    23461 agcattaaaa agagcgaggg gctaattcca aacagcgctt tgataacaac tgaaatcccc
    23521 accataccac ctgaagcaat attattatca acaaacattg tgttaaagcc gatagctgtg
    23581 atgaaggaac caatggttac aaatagtaaa tccattaccc tttttttcat atttaatacc
    23641 tcctttatcg tttagtaaac ataatagacc cattatctcc taaaagaata gaaaccgtca
    23701 agccctattg cttaaaaatc ttagcagctt gacaaatcac ttaaaatgtc atagaatgac
    23761 cctaaactag atgagtaatc tttcccttgt ttttagagag ctagtggttg gtgagagcta
    23821 gcagcaagca agatgaaatg ggctagtgga tcttttgaga ggaaaccata actttcaggc
    23881 ctggcacccc ttatcgtgca atttcttgag ttgagaagat gagatagtat tgattgatca
    23941 gagatactaa ttgaggtggt accgcgtatt tattgtaatg acgccctcac gcaagccttt
    24001 tgcgtgaggg tttttgatgt cataaaatca gtattaagga gaaatcatga caaaaccagt
    24061 tattttaaca ggagatagac caacaggaaa gctacacttg ggacattacg tcggcagtct
    24121 taaaaatcgt gtaagcctgc aaaatgaaaa caagtacaag atgtttgtct ttttggcaga
    24181 tcagcaggcc ttgacggatc acgccaaaga atctgagatg attcgtgagt ctattttcaa
    24241 tgtcgcattg gattatcttt ctgtcggctt ggatccaagt aagtcaacta tttttatcca
    24301 aagtcaggtt cctgaacttg cagagttaac aatgtactat atgaatttgg tgtctcttgc
    24361 tcgcttggag cgtaatccaa ccgttaaaac tgaaattgct caaaagggct ttggtgagag
    24421 tattccagca ggctttttgg tttacccaat ttctcaagct gctgatatca cagccttcaa
    24481 agctaatgta gttcctgttg gtaatgatca aaggccaatg attgagcaga cacgtgaaat
    24541 tgtaagaagc tttaatcata cctataagac agcctgcttg attgagccag aaggtcttta
    24601 cccagaaaat gaaaaggcag gacgtctacc agggcttgat ggcaatgcta aaatgtccaa
    24661 atcactgggt aacggcatct atctttctga tgatgctgac actgttcgtc aaaaagtcat
    24721 gagtatgtat accgatccaa atcatattcg gattgaggat ccgggacagc tagaaggtaa
    24781 tatggtcttt cattacctag atatttttgg ccaaaaagag gacaaagctg atattgaagc
    24841 gatgaaagag cattaccaaa gaggtggcct tggagatgtt aaaaccaagc gttatctgct
    24901 ggatattttg gaaagagagc ttgcgccaat tcgccaacgc cgattggaat acgccaagga
    24961 taagggcgag gtctttcgta tgctagaagc aggaagtcaa aaagcacagg cagtggctgc
    25021 ccaaacattg tctgaagtaa aggttgctat ggggattcgt tatttttaat agcgtagagg
    25081 ctgagaatga ttcttggcct cttatctttt caaatgcacc tatcactcat gagtcaaaac
    25141 ctgtcttttt aatttacaga aatatataga attatgttat tgacaaatga atttagcgtg
    25201 atatgatagt aacaataaaa ataggctggg gtaatattcc ctaaaaaaga agaaaagagg
    25261 attgtgttaa tgtcaaattg ggacactaaa tttttgaaaa aaggctacac gtttgatgat
    25321 gttttgctta ttccggcaga aagtcatgtt cttccaaatg aagtcaattt aaaaaccaag
    25381 cttgctaaaa atttgacatt aaatattcct attattaccg cagccatgga cactgtaaca
    25441 gacagtaaaa tggctattgc gattgcgcgt gcaggtggtc ttggtgttat tcataaaaac
    25501 atgtcaattg ctgagcaggc tgaggaggtg cgtaaggtca agcgctctga aaatggtgtc
    25561 atcattgatc cgtttttcct aacgcctgag cacaaggtag ctgaggctga ggaattaatg
    25621 cagcgctacc gtattagtgg tgttccgatt gtagagacct tagctaaccg caaattagtc
    25681 gggattatta ctaatcgtga catgcgtttt atttctgatt acaacgcccc gatctcagaa
    25741 catatgacaa gtgagcagct ggtgacagct gaggttggga ctgaccttga gacagcagag
    25801 cgtatccttc atgagcatcg gattgaaaag ctaccattgg tagatgataa tggccgtctt
    25861 tcaggtttga ttacaatcaa ggatattgaa aaggttattg agtttccaca tgctgcaaag
    25921 gacgagtttg ggcggttgct ggtagcggct gcggttggtg ttacatcaga tacctttgag
    25981 cgtgcagagg ctttatttga agctggtgca gatgctattg ttattgatac agctcatgga
    26041 cattccgcag gtgttcttag aaaaattgcg gagattcgcg cccacttccc tgataaaacc
    26101 ttgattgcag gaaatattgc tactgctgaa ggcgcgcgtg ccctttatga cgcaggggtt
    26161 gatgtggtta aggttggtat cggaccaggc tcaatttgta caactcgtgt cattgctggt
    26221 gttggggtac ctcaagttac agctatttat gacgcagctg ctgttgctcg tgaatatggc
    26281 aaaaccatta ttgctgatgg tggtattaag tattcaggag acattgtaaa agcccttgca
    26341 gcaggcggca atgctgtcat gttaggctct atgtttgctg ggacagatga agctccaggt
    26401 gagactgaaa tttaccaagg acgcaagttt aaaacttatc gtggcatggg atcaattgca
    26461 gctatgaaaa aaggatcaag cgaccgttac ttccaaggct ctgttaatga agccaacaag
    26521 ctagtgccag aaggtattga aggacgtgtt gcttataagg gagctgcctc tgatattgtc
    26581 tttcaaatgc ttggtggtat tcgctcaggt atgggatatg ttggagctgg tactatccga
    26641 gaattgcatg acaatgctca atttgtagag atgtcaggag ctggtctgat tgaaagtcac
    26701 ccacatgatg tccaaatcac aaatgaagca ccaaattatt ccatgcatta atcctgcagg
    26761 tgtttacttg atgtagtatt tgacatatct attttaaaag ctgagatatt ttctcggctt
    26821 tttttgttgc acgattaaac catgattaga aatgacagct tgctagccct agctatttgc
    26881 tttttagctt tgtgatattt caatgctagg ctaatgatca aatcatactg aatgctctta
    26941 agcgtaatac cttccaaaaa tggcataacc ctaaaaggat taacttaaat agacatgaa
//
LOCUS       DARYXS010000018        26792 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.018, whole genome shotgun sequence.
ACCESSION   DARYXS010000018 DARYXS010000000
VERSION     DARYXS010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26792
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.018"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..600)
                     /locus_tag="TV193_000625"
     CDS             complement(<1..600)
                     /locus_tag="TV193_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1512848.1"
                     /translation="MKRQSNIRRLCHQALAATLITGSLIGTGLLGNKVVYGDMSADVK
                     KIEQVLQSDSGKLKTVLGQISDPNTLFALFAIISADVNIDPESFSFILNGPITPLLSY
                     FNNPNKNDNRKAVVNEIKKRVSALEQAQKLETKAKIEKQIAESELEKTRNAFKVTIEN
                     LHKLEGLLDTEKQKTRKVEEDYQQAKTDKEKAEADKRNAE"
     gene            1005..1649
                     /locus_tag="TV193_000626"
     CDS             1005..1649
                     /locus_tag="TV193_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512849.1"
                     /translation="MPIAAYQYESVVEIISEINRLHYSFSSGLGALLCFNLKKSVSSV
                     VVNNRIDREFQELIVSYKARLNRNISQVSSIRHQFIGIRWRIKQAESISEKLLYYMSE
                     NHEFGRIPLNKCLNDFLGFRILVNNLEVVFAALQNDNRVTNIAKLYLRTDGDYKGIHL
                     YFKNGNNRFFPWELQIWDPEQSRLNELSHKEHKQKRQYISLPQHYFDANLEKEE"
     gene            1654..2403
                     /locus_tag="TV193_000627"
     CDS             1654..2403
                     /locus_tag="TV193_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1512850.1"
                     /translation="MYQHFILVASSYARGERVGFHLATEGQLDHVAIEEKMQRLSHIN
                     RDDVGVHSFVTDSADWQSVIELDSFFEDIMVCQDFDEFEQVLQSDSKISAIDVAKFFL
                     AMRPLSHLQLQKLVYLAYKTYLLAYGESLFDEKIVAFQYGPVVEEVYHSFKKYGSEVI
                     DIDDHTEYILKDIHLPQALGRMLLVEDAKKIVPVLLDVVKQYGDLTGGELVKLTHSEK
                     GPWQTVFRPQLNCEITDEVILAQGRYERLSS"
     gene            complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TV193_000628"
     CDS             complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TV193_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1512851.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TV193_000629"
     CDS             complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TV193_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEL1512852.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSL
                     KGYYKGHKIAKANAAE"
     gene            3125..3955
                     /locus_tag="TV193_000630"
     CDS             3125..3955
                     /locus_tag="TV193_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512853.1"
                     /translation="MFGKLLSLLGFVVALTGCGVSQAEKERVVTEYSPIIIKKFQTLG
                     YQGKITVDDYTKMIETGSERLYFTYSEEVDGKVISLKDSISIATYKSPEEDLADAEVD
                     MGIREEAMWQQPAVKAQAAQIKQLFSELETEDLKLISVTGQSVQTISDSDGELIREDV
                     VRGRNELSQDASNNREAGLSIGGYYHIDVSKYLKNHVLEIRIDFDWRMSEEEQDDLSG
                     PRLDFSDRIKSLDFTCLWDGYYKVGFDRVSRSNRSGDIQDMIVLDIRGGKLVRSFSVL
                     "
     gene            4015..5295
                     /locus_tag="TV193_000631"
     CDS             4015..5295
                     /locus_tag="TV193_000631"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEL1512854.1"
                     /translation="MKLQKPKGTQDILPVAAAKWQYVEGVARETFKQYHYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKE
                     VTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIA
                     VANAPSILDYLDEESQAHFDAVRSMLEVLAIPYVIDTNMVRGLDYYNHTIFEFITEVD
                     QSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIA
                     VLGAYANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADAFKAKVVITLGESEIKT
                     GQAVLKHNQTRQEMTVSFDQIQTNFASIFAECIQ"
     gene            complement(5500..6792)
                     /locus_tag="TV193_000632"
     CDS             complement(5500..6792)
                     /locus_tag="TV193_000632"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1512855.1"
                     /translation="MAINAIFHLYTSVVNIVIVNYFFRQKNGQLATFKNIGYLSFLVF
                     IECCTHFFVSGSYASLITLTCSLVTSLIISSSYRYSMKQCIFWSVTLQSIGILLEASL
                     GIILISLKYQISSISGTFLFINLLTISSIIIIFVLKQLFLKTTDNWLDEQTQTNWILK
                     LSIIPMISLSLLLLQLLRLKEEPLFDLFTILLTLGFIIITITSLYLYTYISDQHLQMQ
                     DINLDRVRFQSELKHLENVKENQLSIRALKHDLHNQNIVLLGLLEQKQYTKAQQLLNH
                     NLNLLDGTDTFFTNDTILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIG
                     NLLDNSIAATIRNQNKAEKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGI
                     KNVQKIVQQYYGLYQQTIDNNIYKVSIIFSNIVLVSQQ"
     gene            complement(6782..7498)
                     /locus_tag="TV193_000633"
     CDS             complement(6782..7498)
                     /locus_tag="TV193_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1512856.1"
                     /translation="MLKIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPCQLIQS
                     LSNDYHIFLLDIEMDNMSGIALAEHIRKDNLSAIIIFLTSHKEYMENIFHVQTFDYLI
                     KPLNEPYFFECLNRALRVLELDKKFFTFSSCHSYYSLSLNDIIYFEKEGRKVLIHTKD
                     KTYSTFLSTKALLKELPEQFIQTHHSYVFNVNYFYKFENNDITLAIDNTRFFIIPISR
                     KFKKGIQENIFSKLRRVNGY"
     gene            7752..7976
                     /locus_tag="TV193_000634"
     CDS             7752..7976
                     /locus_tag="TV193_000634"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512857.1"
                     /translation="MNYSRPCIKDIYPIYKLSDTMFRIGAQINITTEFNDSNYETGAS
                     FTHKLWPHFKECPACGHGNSNDWEIFSHYG"
     gene            7987..8907
                     /locus_tag="TV193_000635"
     CDS             7987..8907
                     /locus_tag="TV193_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512858.1"
                     /translation="MEQYELMVRSLSKRYARDGSYANRDLHCVFKSSEITALIGHNGA
                     GKTTLLNQIIGNIKPDVGDISFLDCSFVKSPKIARKNTSMMPQLHAPLKGITIKQAIS
                     SIGKIRGLSGKLLETEVQELIQELGLIKWQNTVGEKLSGGLKRLTSFAMAVIAAPKIV
                     LLDEPTNDVDPIRRIKLWLYLKKMAAKGHIVIVVTHNILEVEKYADAYYLLEKGEVKS
                     SGAVKTLSSNPKSRISILFRDQKALEEYPFAYSLGGDDNEAITIMDNKEMTALLNWLG
                     IHLSSDTIVQYSITTLGLNDYYEELSDEED"
     gene            8894..9634
                     /locus_tag="TV193_000636"
     CDS             8894..9634
                     /locus_tag="TV193_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1512859.1"
                     /translation="MKKISVTYQFLSLLNWSFIRHKSLILLCSVIQFFMTIALVYGYS
                     LIIADDTVQTVYYLASGSVTIGMITIGCTVSAQSISSDKRDGIVSYIQTLPVLRSLIL
                     LSDLLIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMISMGFAIAYWS
                     TPSTMMLVTQLLLMIGLLFSPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHS
                     ISVVKLVVLLLWLVATALLSVNWLNRQS"
     gene            9791..11539
                     /gene="aspS"
                     /locus_tag="TV193_000637"
     CDS             9791..11539
                     /gene="aspS"
                     /locus_tag="TV193_000637"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEL1512860.1"
                     /translation="MKRSMYAGHVRKEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQANDKLATGAVELKVSGLTI
                     LNTAKTTPFEIKDGVEVSDDTRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGF
                     IDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAY
                     DDAMNHYGSDKPDTRFDMLLQDLTDLVKEIDFKVFSEAQAVKAIVVKGHADRYSRKDI
                     DKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVKSKLTESLQLEHNDLVLFVADT
                     LEVANNTLGALRTRIAKELDMIDMSQFNFLWVVDWPMFEWSEEEERYMSAHHPFTLPT
                     AESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFRALGFTAEEANEQ
                     FGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SEKQLEELQLQIEHHD"
     gene            11532..12479
                     /locus_tag="TV193_000638"
     CDS             11532..12479
                     /locus_tag="TV193_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1512861.1"
                     /translation="MIKKTTYRKRVKYLINRGAKKIGLLHAVKSISKEKYTEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVISAISHHLWGFEIPVALAFYVTNIPLLV
                     LAWYKIGHKFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGLGIGTGFKS
                     RISSGGTDIISLTLRKKTGKDVGNLSLMINGVIMAFAGLLFGWQYALYSMVTIFVSSR
                     VTDAIFTKQKKMQATIVTSCPDKVIHMIHKKLHRGVTSINDAEGTYKHEHKAVLITIL
                     TREEYSEFKWLMLKTDPNAFVSVAENVRIIGRFVESDED"
     gene            12495..13376
                     /locus_tag="TV193_000639"
     CDS             12495..13376
                     /locus_tag="TV193_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1512862.1"
                     /translation="MPANKSLKLKNCCFIILGSAIYAFAFVYFYMANRIAANGLAGLT
                     QVANALFQINPSITGYLINLPLVLLGARLFGRRAMVYTVTGILSLYWFVWLFQQLPLF
                     IDLDHDNLVVSLLAGILGGLGGGIVFRNGGTIGGSDIIAKLIEDRFGLQLNQALLGID
                     IFVIVVSLTYISIPQMMYALIASFMYSRIVHLVQNGGYSARGTFIISDYSQTISQFIM
                     EELGRGVTYLHGEGAYSGREKQVIYVALGRSDVRELKAFIAQVDPNAFVSFFDVNEVN
                     SPEFIATKSKYHKTKKR"
     gene            13520..14434
                     /locus_tag="TV193_000640"
     CDS             13520..14434
                     /locus_tag="TV193_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1512863.1"
                     /translation="MTNLDKWHRVRELLLIAVGVAIYTFGFVNFNMANELAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFMLGAKIFGRRSLALTIYGTVLMSVFIWLWQKVPM
                     ELGLENDMMLVAVVAGLFAGIGSGLVFRYGATTGGTDIIARIAEEKFGAKLGQTLLFV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKQSQAAAQAI
                     LTEINRGVTYLKGQGAYSGHDYNIMYVTLNPTEVREVKRILAELDPDAFISIIDVDEV
                     ISSDFKIRRKNFDKPIEKALQKKSNMLK"
     gene            14606..16000
                     /locus_tag="TV193_000641"
     CDS             14606..16000
                     /locus_tag="TV193_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1512864.1"
                     /translation="MEALSIQHYALDTAEKNLLTIDSLTLNQGERVFIIGDNGAGKTS
                     FLKTIIGESTNYSGFLQVHGDIAYVPQIKSTSPQSGGERAMSYLKEAFQARPSLLILD
                     EPSSYLDHANRDWLINQLKRYRGTLLVVSHDRYLINQLSQKIWLLEHQTIKTYHGNYD
                     DYQRSRQLEEDKQLRAFLEYQRKTNQLKKSLTRKKVQANKMAVKKKSVSRSDWKTNSF
                     AGSYDSQAKAMAKAAKAMENRLTRMKEVNSPRKKAWAKLKKDPNEGALPNTLLHLQEG
                     TLTRDHQLLFDYPGIVIRSHSRIAIIGRNKAGKSSFLDQLAAQALSGFYAQNLRITYF
                     KQDQADLEPDQTAVELISRQSSQDRVTILNYLAMMGIDYDKANQKVAVLSGGERVRLA
                     LVAALLTDHQLLILDEPTIYLDLVAIEALESCLIDYPAALLLVSHDLAFVNKVATEIY
                     EVKDHHLTAYHFED"
     gene            complement(16048..17739)
                     /locus_tag="TV193_000642"
     CDS             complement(16048..17739)
                     /locus_tag="TV193_000642"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEL1512865.1"
                     /translation="MDTKTLIAAEIAKIVPELEQAAIFNLLETPKNSDMGDLAFPAFS
                     LAKALRKAPQAIASDLAERIDASQFEKVAAVGPYVNFFLDKASISAQVLTQVIADGAD
                     YAQQDEGQGRHIAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGNEAAVQAHPIDELLKLYVRINAEAETDPSLDEEAREWFRRLE
                     ERDQEATELWQWFRDESLIEFNRLYDQLGVSFDSYNGEAFYNDKMDEVLELLEDKGLL
                     VESKGAKVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAISR
                     AANQIEAKNPKLANKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKASFTPATDTSYSLNDPESWEIIKLIQDFPRIIKRAFDNFEPSIMA
                     KFAIHLAQSFNKYYAHTRILEDDPERDNRLALCYATAIVLKEALRLLGVEAPNEM"
     gene            18016..18453
                     /gene="argR"
                     /locus_tag="TV193_000643"
     CDS             18016..18453
                     /gene="argR"
                     /locus_tag="TV193_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1512866.1"
                     /translation="MNKIERQQQIKQLIQAEHIGTQEEIRRLLQKDGIVVTQATLSRD
                     LREIGLLKLRDDRGKLYYSLSEPVATPFSPDVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDVLGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            18455..18805
                     /locus_tag="TV193_000644"
     CDS             18455..18805
                     /locus_tag="TV193_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1512867.1"
                     /translation="MPYRESLHQLIAALEKHSSIIAYKEAQQHLLQRTDYNQKAYQMK
                     RHQQDTYLFRQIAKDKAAEESAFKAQQLREDLDHQPLIDDYRDKMQNASDLVRYITGT
                     IEDELNKEFNDGKG"
     gene            18792..21347
                     /gene="mutS"
                     /locus_tag="TV193_000645"
     CDS             18792..21347
                     /gene="mutS"
                     /locus_tag="TV193_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEL1512868.1"
                     /translation="MAKANVSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QILEIGLTSRNKNADNPIPMAGVPYHSVQQYIDVLIDLGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTAVDSSRPDSPNNFLVAVDFDGKAYGLSYMDVSTGEFFATDLADFAS
                     VKSEIQNLKAKEVLLGFELSEEEQAILVKQLNLLLSFEMTALEDSPLIDHQLTAVELS
                     AAGKLLHYVHQTQLRELSHLQALVHYDIKDYLQMSYATKSSLDLLENARTGKKHGSLY
                     WLLDETKTAMGMRLLRAWIDRPLVTSEAILERQEIIQVFLNAFIERTDLSDSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAKVPYIKAILEAFNSPYLDKLVNQIDTLPELEH
                     LIRSAIDPDAPATINEGNIIRTGFDERLDHYRKVMREGTGWIADIETKERQASGISNL
                     KIDYNKKDGYYFHVTNSNLGMVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMRIRAQVETYIDRLQQLAKALATVDVLQSLAVVAEKNHYVRPLFNQESKIA
                     IDNGRHAVVEKVLGVQEYIPNSISFGPQTSIQLITGPNMSGKSTYMRQLALTVIMAQI
                     GSFVAAESASLPLFDAIFTRIGAADDLISGQSTFMVEMMEANHAIKRATPHSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDRVGAKTMFATHYHELTELSTKLTKLVNVHVATLEK
                     DGNVTFLHKIAEGPADKSYGIHVARIAGLPEDLLARADTVLTKLEAQSQARESVLSTT
                     EVRETQQLANQQLSLFTDDGSSSEIIKRLESVDVMNLTPIQAMTVLYELKKLL"
     gene            21494..23476
                     /gene="mutL"
                     /locus_tag="TV193_000646"
     CDS             21494..23476
                     /gene="mutL"
                     /locus_tag="TV193_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEL1512869.1"
                     /translation="MTTIIELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKLTIKTATADAEHGSILVASGGKIEQLEAVSTPVGTKIKVENLFYNTPARLKY
                     MKSLQAELAHVVDVVNRLSLAHPEIAFTLISDGKQLTQTSGAGDLRQALAGIYGLNTA
                     KKMIDISSADLDFEVGGFVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKERELMALISTAISESLREQDLIPD
                     ALENLARSSTRSFSKPEQTSLPLQPSQLYYDPQKNDFFTKETVVSEDSPQGFNHETLV
                     DSGVKQVDNLQLAKTESEAAAPSVKYASRPDPMLSDGEHPGLDVHNKQKLSQMLDRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGRDGLFIIDQHAAQERVKYEYYRDKIGEVDNSLQ
                     QLLVPYLFEFSGSDFINLQEKMSLLNEVGIYLEPYGNHTFILREHPIWMKEAEIESGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            23487..24710
                     /locus_tag="TV193_000647"
     CDS             23487..24710
                     /locus_tag="TV193_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1512870.1"
                     /translation="MREFFQLPKQIQIRQFVRFITITLGSSIFPFMAMYYTSYFGAFW
                     TGILMMVTSFTGFIGTLYGGHLSDAIGRKKVIMLGSVASTLGWLLTILANVPKTVLPW
                     LTFVGILLVELASSFYAPAYEAMLIDLTDDSNRRFVYTINYWFINIAIMLGAGISGLF
                     YDRYFLELLIALLIINIVCFGIAYRYFGETRPEHYRFEHGIGILAGFANYRQVFKDRA
                     FVLFTIGTILFSSIWLQMDNYVPVHLKLYFEETDVLGIHLTSSKMLSLMVFTNTLLIV
                     LLMTVINRLTARWRLLPQLVIGSVIFAFGMLLSFTFTGFFAIWCSVVVFTIGEMLNVP
                     ANQVLRAEMMDQSKIGSYTGFVSMAQPLGAILAGLLVSLSHFTGQAGVQLAFVLIACV
                     GLYVIVLSAKMKKKV"
     gene            24712..25308
                     /gene="ruvA"
                     /locus_tag="TV193_000648"
     CDS             24712..25308
                     /gene="ruvA"
                     /locus_tag="TV193_000648"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEL1512871.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMITVANPYSFTDCVNQQV
                     TIYLHQVIREDAQLLFGFHSEEEKDVFLKLISVSGIGPTTALAIVAVDDNRGLVNAID
                     NSDITYLMRFPKIGKKTAQQMVLDLAGKFVEAPKEESSKPPKAKQQGNEQLDEAVEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKMLMKG"
     gene            25318..25869
                     /locus_tag="TV193_000649"
     CDS             25318..25869
                     /locus_tag="TV193_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEL1512872.1"
                     /translation="MKRCAWVPQDNKLYCDYHDLEWGRPVYDDRALFELLCLESYQSG
                     LSWLTVLKKRPAFRSVFHHYDISAVASFSEQEMAAALQNAAIIRHKPKLIATVNNAAA
                     VQRIQQEYGSFSSYLWNFVGGQPIDRLVNDDNPAPAQTALSLKLSKDLKKRGFKWLGP
                     TTVYSFMQAAGLVNDHEENCEFR"
     gene            complement(26305..>26792)
                     /locus_tag="TV193_000650"
     CDS             complement(26305..>26792)
                     /locus_tag="TV193_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1512873.1"
                     /translation="VMISLRKKGVKNNQDLQELAYKIWNSLVKQDTWYEKDLQLLHTI
                     LFHFPIEIIENISQKILDSLAKYKDYRNIKSSEYALLTNLSTIYLYHNLKKECEEITL
                     LTIKLARQLKRYDSLGFSQVRLGICRNDDHLINKGLQLLQLTEETELLETLQHELKNY
                     R"
BASE COUNT         7752 a         4685 c         5934 g         8421 t
ORIGIN      
        1 ttccgcattc cttttatcag cctctgcttt ttctttatcg gttttagctt gttggtaatc
       61 ttcctcaact tttcgagttt tttgtttttc agtgtctaat aatccctcta gtttatgtaa
      121 attttcaatt gttactttga aagcattcct agttttttct aattcacttt ctgcaatctg
      181 tttctctatt ttagctttag tttctaattt ttgagcttgc tccaaagctg agactctttt
      241 ttttatttca ttaacaactg cctttctatt atcatttttg tttggattgt tgaaatatga
      301 taataatggt gtgattgggc catttaatat aaaactaaaa ctttctggat ctatatttac
      361 atcggctgat ataatagcaa ataaagcaaa caatgtattg ggatcactaa tttgtcctaa
      421 tactgttttt aacttaccac tatctgattg taaaacttgc tcaatttttt ttacgtccgc
      481 actcatatct ccatacacaa ctttatttcc aagtagtcct gttcctatca ggcttcctgt
      541 gatgagagta gctgctaggg cttgatgaca caagcgtctg atgtttgatt gtcttttcat
      601 gatttagtcc tcacatatcg tcgaatgttt tttctaaaat tcttccaaaa aatcttaaca
      661 tgacgcttgc aggctgtgaa tacgttttgg gcaattcgcc tccgtagttt cgtttttttt
      721 aattcaatca ttaaacgtct gattttatca tgatataatt gatcttgttc aaggctgatc
      781 aggaaattct tgatgaagat gacagcttta tatcggtgtt tgggaaacca taagattggc
      841 aaggctacgc tgggcttagc tgacattgtt gcttcaaaat gctttcaggt gtagaaatgt
      901 tgacaagtat tctttaaaaa gatagactat agctagtagg atagaggtat gcacaggtga
      961 cagatgtgat acttgtgttt tttgctattt ttggaggttt ctgattgcct attgcagctt
     1021 atcaatatga aagtgttgtt gagattatta gtgaaatcaa tcgattacac tattcatttt
     1081 cttcgggttt aggagctctt ctatgcttta atttgaaaaa gagtgtcagt tcggtagtcg
     1141 ttaacaatcg tattgatagg gagttccaag agctcatcgt ttcttataaa gcaaggctaa
     1201 ataggaatat tagtcaagtc tcaagcatac gacatcagtt tataggcatt agatggagaa
     1261 taaagcaagc agaatctatt agtgagaagc ttttatacta catgagcgag aatcatgagt
     1321 ttggaaggat tcccttaaat aaatgtttga atgattttct tggatttagg atcttggtca
     1381 ataacttaga agttgttttt gctgctttgc aaaatgataa tcgagtgact aatattgcta
     1441 aattgtattt aagaacagat ggcgactata aaggtatcca tctatatttt aaaaatggaa
     1501 ataatcggtt ttttccatgg gaattacaga tttgggatcc agagcaatca cgcttaaatg
     1561 agctgtcaca taaagagcat aagcaaaaac gacaatatat atcactaccc caacattatt
     1621 ttgatgctaa tttagaaaag gaggaataac cgcatgtatc agcattttat tttagttgct
     1681 agttcatatg caagaggtga gagagttggc tttcacttag cgacagaagg tcaattggat
     1741 catgttgcca ttgaagaaaa aatgcagcgg ctgagtcata tcaatagaga tgatgttggt
     1801 gtgcattctt ttgttacaga tagtgctgat tggcaaagtg tcattgagtt agattccttt
     1861 tttgaggata ttatggtttg tcaagacttc gatgaatttg aacaggtttt acaatccgac
     1921 tctaaaatta gtgctattga tgttgctaaa tttttcttag caatgcgtcc actctcacac
     1981 ttacaattgc aaaagttagt ttatcttgct tataaaacat atcttcttgc ctatggtgaa
     2041 tccttatttg atgaaaaaat agttgctttt caatatggtc ctgtagtaga agaggtgtat
     2101 cacagcttta aaaaatatgg ttctgaggtg atagatatcg atgatcatac agaatatatt
     2161 ttaaaagaca tacatcttcc gcaagcctta ggtagaatgc tattggtcga agacgcaaag
     2221 aagattgtgc ctgtattatt agatgttgtt aaacagtatg gagatttaac aggaggagaa
     2281 ttggttaagc tgacgcactc tgaaaaggga ccttggcaga cggtttttcg tccacagtta
     2341 aattgtgaga tcactgatga ggttatttta gcccaaggca gatatgaaag attatcatca
     2401 taagtacctt tgcttattgt attagctgag aatactcagt tgtctcatca aaaccaaaac
     2461 aaaaaagcct ttgaaacgtt gatttcaagg gctttctgta tatcgtctta ttttacctct
     2521 gtaaacacaa catgtttacg tagttttggt gagtattttt tcaattgaag gcggtctgga
     2581 gtgttacgtt tgttttttga agtaaggtac aagcgttcac cagattcttt gtgttcaagt
     2641 gtgatattta cgcgcatggt atctcccttc tattattcag ctgcgttagc tttagcgatt
     2701 ttatgtcctt tgtagtatcc cttaagtgag acacgatgtg aacgtgagta atctccagtt
     2761 gtttcgtcaa attttactga tggtgcagtc aatttgtagt gtgtacgacg tttgttcttt
     2821 ttagcttttg acgtgtgacg tgcaggaact gccatttttt ctatcctccg ttaaatgatc
     2881 aagggtctat taaaagattg gtgacaaact ggtgtgcatg atcttatgct aacctatctg
     2941 tctcaaatct ttgacccatt gttatctatt tgatgttatg gctttcgcca actttagtat
     3001 catatcatat cttctatgta aagtaaagtt acttgacaaa aattttatta aaaagctctg
     3061 ctattctcca aaaatcctaa aaaatggtaa aatgagacaa aggtggttat tttaggagat
     3121 taagatgttt ggaaaattat taagtctgtt aggctttgtc gttgctttga ctggttgtgg
     3181 tgtttcacag gcagaaaaag aacgtgttgt aacagagtat agccccatta ttattaaaaa
     3241 atttcaaacc ttaggatacc aagggaaaat cactgtagac gactatacta agatgattga
     3301 gacaggtagt gagagacttt attttaccta cagcgaagaa gtagacggta aggttattag
     3361 tctgaaggat agtatttcga ttgctaccta taaatcacct gaggaagatt tggctgatgc
     3421 agaagttgac atgggaatta gggaagaagc tatgtggcag caaccagctg tcaaagcgca
     3481 agctgctcag atcaaacaac tatttagcga gttggagact gaggatttga agcttatatc
     3541 cgtaacagga caaagtgtcc agacgatttc tgattcagat ggagagctga ttagggaaga
     3601 tgttgtacga ggcaggaatg aattatctca agatgcatct aataatagag aagctgggct
     3661 atcaataggt ggctattatc atattgatgt ttcaaagtat ttgaaaaatc acgtgttgga
     3721 aattcgtata gattttgatt ggcgaatgtc agaagaggaa caagacgatt tgtctggccc
     3781 caggttggat ttttctgata gaataaaaag tctagacttt acctgcttgt gggatggcta
     3841 ctataaagtg gggtttgaca gggtgagtag atctaatcga agtggagata ttcaagatat
     3901 gattgtttta gatattcgag gcggtaaatt ggttcgtagc ttttctgtac tttaacagat
     3961 taatgaagct attctatggt aaaatatata aatactagta aaagaggaaa taaaatgaag
     4021 cttcaaaaac caaaaggaac acaggacatt ttgcctgtgg ctgctgctaa gtggcaatat
     4081 gttgaaggtg ttgcacgtga aacctttaag caataccatt atggtgaaat ccgaacacct
     4141 atgtttgagc attatgaggt cattagccga tcagtaggtg ataccactga tattgtgacc
     4201 aaggaaatgt atgacttcta tgataagggc gaccgtcata tcacacttcg tccagaagga
     4261 acagccccag ttgttcgttc gtatgtggaa aacaagctct ttgcgccaga ggttcaaaag
     4321 cctgtcaagc tgtattatat tgggtcaatg tttcgttatg agcgtccgca ggccggccgt
     4381 ttgcgtgaat ttcaccagat tggtgtagag tgctttggct ctgccaatcc tgccactgat
     4441 gttgagacga tcgccatggc ttatcacctc tttgaaaggc ttggtattaa agaggtgacc
     4501 ttgcatttga atagccttgg aaatgcagct agtcgcgcag cctatcgtca ggccttgatt
     4561 gattacctat ctccaatgcg tgagaccttg tccaaggata gtcagcgccg tttagatgaa
     4621 aaccctctgc gcgtgcttga ttccaaggaa aaagaggata agattgcagt agcaaatgcc
     4681 ccatctattc ttgattatct tgacgaggag agtcaggctc actttgatgc tgtgcgcagc
     4741 atgcttgaag tacttgctat tccttatgtt attgatacca atatggtgcg tgggcttgat
     4801 tattacaacc acacgatttt tgaattcatt acagaggtgg atcagtctga gctgacgatt
     4861 tgtgctggtg gtcgctatga tggtcttgtg gagtattttg gtggaccagc aacccctggc
     4921 tttggttttg gacttggttt ggaacgtctt ttgcttatcc ttgataagca aggcgttgaa
     4981 ctgccagtcg aagaaggctt ggacgtttac atagctgttt taggggctta cgccaatgtg
     5041 gcggcgctag ccttgacaca ggccattcgc cgtcaggggt tcaccgtaga acgcgattac
     5101 ctcggacgta aaatcaaagc acaattcaag tcagctgatg ctttcaaggc aaaggtagtc
     5161 atcaccctag gtgaaagtga aatcaaaaca ggtcaagctg tccttaagca taatcaaact
     5221 cgtcaagaga tgacagttag ctttgatcaa atccaaacaa attttgccag catttttgca
     5281 gaatgtatcc agtaaagcaa aaaaactgaa aaaagtggta tgagtcatta agatactaaa
     5341 aaatcacaca acgtcgttgc tttaatagca atgatattgt gtgattttgt gatgttatac
     5401 ctatactaag gactattttt cctattttta gtagtcagtt tgaaagcact cttgtttgga
     5461 atggcagcag ctatgcttat agctggtgat gggttaatgc tattgttgag aaactaaaac
     5521 aatgttagag aagataatgc tgactttata gatgttattg tctatggttt gctggtatag
     5581 tccataatac tgttgaacaa ttttttgaac atttttaatt cccaatccgt cttttttccg
     5641 ttgacttctg gaggcaagct cttttggatc aaaaaagttt tcgatatcaa tgtggagttg
     5701 atttttaaag agtctcacct ttaattgtat ttgtttttca gctttatttt gattgcgaat
     5761 agttgcggca atgctattat caagtagatt tcctataatg actgaaataa cttcagtctt
     5821 taggcttatg tttgtaggga taaggcagtg aatatctaac acaatgccat tctttttggc
     5881 tacgactgct ttttgattaa gtaaataatt taaaatagta tcattggtaa agaaagtatc
     5941 tgtcccatct agcaggttaa ggttatgatt cagtaattgt tgggctttag tgtactgctt
     6001 ttgctccaga agtcctaata ggacaatgtt ttgattatgt agatcatgct taagagccct
     6061 aatgcttaat tgattttcct ttacattttc taaatgcttc agttctgact ggaatcgtac
     6121 cctatctaag ttaatgtctt gcatttgtaa atgctgatct gaaatgtaag tatacagata
     6181 cagcgaagtg attgtgataa tgataaatcc aagtgttagc agtattgtaa acaagtcaaa
     6241 taaaggttct tcttttaatc gaaggagctg tagcagtagc agagaaagac ttatcattgg
     6301 aataatagat agctttagta tccagttggt ttgtgtttgc tcatcaagcc aattgtctgt
     6361 agtctttaaa aagagctgct ttaacacaaa tataatgata atactggata tggtaagcag
     6421 gtttataaat aaaaatgtcc cactgataga agagatttga tatttaagag atattaaaat
     6481 gatccctaag cttgcttcta gcaggatacc tatgctttga agtgtaacag accaaaagat
     6541 acactgtttc atggagtaac gatagctact agatattatc agtgatgtta ccaaagaaca
     6601 agtcagggtt atcagtgagg catagcttcc tgatacaaaa aaatgagtgc agcattctat
     6661 gaatactaaa aaagagagat aacctatgtt tttaaaggta gctagctgac catttttctg
     6721 acgaaaaaaa taattaacaa tcacaatatt aacaactgat gtataaagat gaaaaatagc
     6781 gttaatagcc atttactctc cttagcttgg aaaagatgtt ctcctgaata cccttcttaa
     6841 atttccgact gataggaatg ataaaaaagc gcgtgttatc aatagctaat gttatgtcat
     6901 tgttttcaaa tttatagaag taattgacgt taaacacata agaatgatgg gtttggataa
     6961 attgttcagg aagctctttt agtaatgctt tggttgataa aaaggtagag taggtcttgt
     7021 ccttggtatg aatgagtact tttcgtcctt ccttttcaaa atagataata tcgtttaagc
     7081 ttaagctata gtaggagtgg caagatgaaa aggtaaaaaa ttttttgtca agctctaaaa
     7141 cccttagagc tctatttagg cactcaaaaa aatagggttc atttaaaggc ttaatcaggt
     7201 aatcaaaggt ttgcacgtga aaaatgtttt ccatgtattc tttgtggctt gttaaaaaga
     7261 taataatagc agagagatta tctttcctaa tatgctcggc taatgctatt ccagacatgt
     7321 tatccatttc aatgtcaaga agaaaaatat ggtaatcatt agacagtgac tgtattaatt
     7381 gacaaggatc ctcgtaaatg tctaactcca ctggaactaa ttgattatat tggtataata
     7441 gatcttctac agctgttgca aaagctttat tgtcatcaca aagagcaatt ttaagcatgg
     7501 tacccccata atcctataga ctgtggtatt tagtatacca aaaatgacat gaaaagcgct
     7561 attttttaca aaataataat aatagactga atgttttgat aaaatgaatc tatgaaatga
     7621 gggagcaata atgactgaag taacagtgcg taaaccgatg gaaacaatgg aagtttcatg
     7681 ggtagtcatt taaatactct aaagtgggct gtttttatca gcctacttta atatttttag
     7741 gagggtaaaa aatgaattat agcagacctt gtattaaaga tatttatcca atttataaac
     7801 tgagtgatac catgtttcga ataggcgctc aaattaatat tacgacggaa tttaacgatt
     7861 caaattatga aacaggtgct tcatttacac ataagctttg gccacatttc aaagagtgtc
     7921 cggcttgtgg tcatggcaac agtaatgatt gggaaatatt tagtcattat gggtaggagt
     7981 taatcaatgg aacaatatga attaatggtg aggtcacttt caaaaaggta tgccagagat
     8041 ggctcttatg ccaataggga tttacattgt gtctttaaat ccagtgaaat aacagccttg
     8101 ataggtcata atggagctgg taaaacaact ctactaaacc agattattgg taatataaaa
     8161 cctgatgtgg gtgatatttc atttctagac tgttcgtttg tcaagtcccc taaaattgct
     8221 agaaaaaata cgtcaatgat gcctcagcta catgccccct taaaaggaat cacaattaaa
     8281 caggctattt catcaattgg aaaaatcaga gggctgtccg gaaaattatt ggagacagag
     8341 gttcaggaat taattcaaga actcggtctt attaagtggc aaaatactgt cggagagaaa
     8401 ctctctggtg gactaaaaag attgacgtcg tttgcaatgg ctgttattgc tgctccgaag
     8461 attgttttac tagatgagcc gacaaatgat gttgatccta taagacgtat aaaattatgg
     8521 ttatacttaa aaaagatggc ggcaaaggga catatcgtta ttgttgtcac ccataatatt
     8581 ttagaggttg aaaaatatgc agatgcttat tatttgcttg aaaaggggga agtaaaaagt
     8641 tcaggagcgg taaaaaccct atccagcaat ccaaagagta gaatatccat tttatttaga
     8701 gatcaaaaag ccttggaaga atacccattt gcttactcac ttggtgggga tgacaatgaa
     8761 gctataacaa taatggataa taaggaaatg acagcattat tgaattggtt aggcatacat
     8821 ttgtcatcag ataccattgt tcaatatagt atcacgacgt tagggttaaa tgattattat
     8881 gaggagctgt cagatgaaga agattagtgt tacttaccaa tttctaagct tgttaaattg
     8941 gagctttatt cgccataaat cgttgatatt attgtgtagc gttattcaat tttttatgac
     9001 aattgcactg gtttacggtt attcacttat tattgctgat gatactgtgc aaacagtcta
     9061 ctatcttgct tctggctcag taacgattgg tatgattacc attggctgta cggtatcagc
     9121 acaatcaatc agtagtgata aaagagatgg cattgtgagc tatattcaaa cgttacccgt
     9181 cctaagaagt ttgatcctgc tatctgatct attgatttgg acattaactg ctttgattgg
     9241 tgttggtgtg tcaattgcgg ttgtttattt aaaatttcaa atattgcccc agctgtcctt
     9301 agcgacgttt cttattttgc cattagtttt aatgacaatg atcagtatgg gttttgccat
     9361 tgcttattgg tcaactccaa gtacgatgat gctggtaacc caattattgt tgatgattgg
     9421 cttattgttt tcacctataa tgtatcctgc agaacgtata cctgaggtga ttttaagggg
     9481 atatcatttt ctgccattta taccagcagg agacttgatt cgagagacgg tttatttggg
     9541 gcattccatt tcagttgtca agcttgtggt gttactgtta tggctggttg ccactgcctt
     9601 actttcagtc aattggctaa acaggcaaag ctaaggtata ggctctgcta tttcttaaaa
     9661 actctactca aatgggtggg gtttttaatt gttttttgtt ataataagtg gtaatgatat
     9721 ttttaattag agaaaggaac aaagacaggt agggagtgtt gactctttat ttgctcttgg
     9781 tatcttattt atgaagcgta gcatgtatgc aggacacgtc cgaaaggaac atattggaag
     9841 aacgattgtt ttaaaaggtt gggtaagtcg ccgtcgtgat ttgggcggcc ttattttcat
     9901 tgatttgcgt gatcgtgaag gagtgatgca gctggttatt aatccagagg acgtttcagg
     9961 tgatgtgatg gcgactgctg agcgcttacg cagtgaatac gtgattgagg tggaaggaag
    10021 tgttgaggcg cgtcagcagg ctaatgataa gctagctaca ggtgcagtgg agctaaaggt
    10081 ttcaggcttg accattctta atacagctaa aacgacaccg tttgaaatca aggacggtgt
    10141 tgaggttagt gacgatacgc gtttacgcta ccgttattta gatcttcgtc gtccagaaat
    10201 gctggaaagc tttaagcttc gtgccaagac gacgcatgtt atccgtaatt acttggataa
    10261 tcttggattt attgatgttg agacaccgat gttgacaaag tcaacgccag agggagcgcg
    10321 tgattacctt gtaccaagcc gtatcagcca gggacatttc tatgctttac cgcaaagccc
    10381 acaaatcaca aagcaattgt taatgaatgc gggctttgat cgatattacc agattgttaa
    10441 gtgcttccgc gacgaagatt tacgaggaga tcgtcagcct gagtttacac aggttgactt
    10501 ggaaacgtca tttttatctg agcaagaaat ccaagatatt gttgagggta tgattgcaaa
    10561 ggttatgaag gatacaaagg gcatagaggt taagctgcca tttccgcgca tggcttatga
    10621 tgacgccatg aatcattatg gctcagataa gccagataca cgctttgata tgcttttaca
    10681 agacttgaca gatcttgtca aggagattga ctttaaggta ttttctgagg cacaggctgt
    10741 taaggcaatt gttgtcaaag gacatgcgga tcgctactcg cgaaaggaca ttgataagct
    10801 gacagaattt gctaagcaat ttggtgctaa gggtctggca tggctgaagg tggttgatgg
    10861 tgcatttact ggaccaattg ctaagttctt gacaggtgtg aaaagtaagt tgacagagtc
    10921 tttacagctt gagcataatg atttggtctt gtttgttgca gacaccttag aggtagccaa
    10981 caatacccta ggtgctcttc gtacacgtat tgcaaaagag cttgacatga ttgacatgtc
    11041 tcagtttaat ttcctatggg tggttgactg gcccatgttt gaatggtctg aagaagagga
    11101 gcgttacatg tctgctcatc acccatttac attaccaaca gcagagtcag cccatgagct
    11161 agagggtgat ttagccaagg ttcgcgctgt tgcttacgat attgtcttaa atggctatga
    11221 gcttggtggc ggaagccttc gtatcaacca aaaagacatg caagagcgta tgtttagagc
    11281 actaggcttc acagctgagg aggccaatga gcaatttggc ttcttactag aggctatgga
    11341 gtatggcttc ccaccacatg gtggtcttgc tattggtctt gatcggcttg tcatgctgct
    11401 tgctggcaag gacaacattc gagaggttat tgcctttcct aaaaacaata aagcatctga
    11461 tccaatgaca caggcgccta gtctggtatc tgaaaagcaa ttagaggagc ttcagcttca
    11521 aatagaacat catgattaaa aaaacaacct ataggaaaag agtaaaatac ctgattaata
    11581 gaggagccaa aaaaattggc ttgcttcatg ccgtaaaaag catttccaag gagaagtata
    11641 cagagaaaat ttcggcctct ttactctatg gcatattgtc tagtatagct gttaatttct
    11701 ttttccaacc gggccatgtc tactcaagtg gtgcaacagg acttgctcag gttatctctg
    11761 ccatcagcca ccatttatgg ggctttgaga ttcctgttgc tttagctttt tacgtgacta
    11821 acattcctct tttagtctta gcttggtata agattggtca taaatttacg atttttacct
    11881 ttattaccgt tagtatgagc tctttcttta tccaaatcat gcctcaggtg accttgacga
    11941 ctgacccact gattaatgct atatttggtg gcttggttat gggtttgggg atcggtacag
    12001 gcttcaagtc tcgcatttct agtggtggta cggacattat cagtctgaca cttagaaaga
    12061 aaacaggaaa agatgtcggt aacctttcat tgatgatcaa tggtgtgatt atggcttttg
    12121 caggactgtt gtttggctgg cagtatgcgc tttattcgat ggtgactatt ttcgtttcta
    12181 gtcgagtgac tgatgcgatt tttaccaagc aaaagaaaat gcaggcgacc attgtgacca
    12241 gctgtcctga caaggtgatc cacatgattc ataaaaagct gcaccgaggg gtaaccagta
    12301 tcaatgatgc tgaaggcacc tacaagcatg agcataaggc tgttttaatt acgattctca
    12361 cacgtgagga atatagtgaa tttaagtggc tgatgcttaa aacagatcca aatgcttttg
    12421 tttctgttgc tgaaaatgtt agaatcattg gtcgctttgt cgaatcagat gaagactaag
    12481 aaataggtat caatatgcca gctaataaga gcttaaagct taaaaattgt tgttttatta
    12541 ttcttggctc agctatttat gcctttgcct ttgtctactt ttacatggca aatcgtattg
    12601 ctgctaatgg gctagcggga ctgacgcagg ttgctaatgc cttgtttcag atcaatcctt
    12661 caataacggg ttatctgatt aatttgcctc tcgtcctgtt gggtgcaagg ctctttggca
    12721 gacgggcaat ggtgtatact gtgaccggta ttttatcact ttattggttt gtttggctgt
    12781 ttcaacagct cccccttttt attgacttag atcatgacaa tttagtagtg tccttgctgg
    12841 caggaattct tggtggttta ggtggcggca ttgtttttag aaatggtggg acgattggtg
    12901 gctcagatat tattgctaag ctgatagagg ataggtttgg cttgcagctc aatcaagcct
    12961 tattagggat tgatattttt gtcattgtgg tttctttgac ctatatttca ataccgcaga
    13021 tgatgtatgc tttgattgct agctttatgt atagtaggat tgttcatctg gtgcaaaatg
    13081 gtggctattc tgcacgcgga acctttatta tttcagatta ttctcagact atttcacaat
    13141 tcattatgga ggagctcggt agaggagtca cctatttaca tggtgagggt gcttactctg
    13201 gtcgtgagaa acaggttatt tatgtagctc taggtcgatc agatgtacga gagctaaagg
    13261 cctttatagc acaggttgat cccaatgctt ttgtttcttt ctttgatgtt aacgaagtca
    13321 atagtccaga atttattgcc acaaaaagta aataccataa aacgaaaaaa agataaaggc
    13381 tggaatatca cattcatagc ctttgattat gctaatgaaa gcgcttggct attaagctta
    13441 ttgtagtgta gctattaaat ggccgtcctt gagctttcat ctggtaccta acaaatgtaa
    13501 tgaatagtga ggaaagtgaa tgacaaatct tgacaaatgg catcgtgtaa gagagctatt
    13561 attaattgcg gtgggtgttg ctatctatac ctttggtttt gttaatttca acatggctaa
    13621 tgaattggct gagggtggcg tagctggaat taccttgatt ttgcatgctc attttgggat
    13681 caatccggct tattcgtcac ttttatttaa tctgccttta tttatgttag gggctaagat
    13741 ttttggaagg cgctccctag ccttaacgat ttatggaacc gttcttatgt cagtctttat
    13801 ctggctgtgg caaaaggtgc ctatggagct tggtttagag aatgatatga tgcttgttgc
    13861 ggttgttgca ggcttgtttg caggaattgg tagtggcctt gtttttcgat atggagcgac
    13921 aactggtggg actgatatta ttgcccgcat tgcagaggaa aagtttggtg ctaagctggg
    13981 gcaaaccctg ttatttgtag atgccttggt attaacagcc tctctcactt atgttgattt
    14041 gaagcatatg ctctatacat tagtggctag ctttgtcttt agccagatga ttagtgttgt
    14101 tcaaaatggt ggctatacca ttcgtggtat gattattatc actaagcagt cgcaagccgc
    14161 ggcgcaggcg atcttgacag aaatcaatcg aggagtgact tatttaaagg gacaaggcgc
    14221 ttattctggt catgattata atattatgta cgtgacgctc aatccaacag aggtgcgaga
    14281 ggtgaagcgt attttagcag agctagatcc agacgccttt atctctatta ttgatgttga
    14341 tgaggtaatc agctcagact tcaagattcg tcgcaaaaat tttgacaaac caattgagaa
    14401 ggctttacag aaaaaatcca acatgttaaa ataaagaaaa taagcagaaa taagaggttg
    14461 agaaaagcca tgattaacaa ttaactcatt gtcaagcact aatctatgat taacagcaag
    14521 ggattagtgt ctgctttgag gcttgggaat cagggctttt tgtgtgcact ttttcaggcc
    14581 tttctgatga tagaaaggaa taaatatgga agcacttagt attcagcatt acgctttaga
    14641 tacagcagaa aaaaacttat tgacaataga ttctcttaca ttgaatcaag gtgagagggt
    14701 tttcatcatt ggtgataatg gggctggaaa gaccagcttt ttaaagacaa ttatcggaga
    14761 aagcactaac tatagtggct ttttgcaggt gcatggagat attgcttatg ttccgcaaat
    14821 caagtccact agccctcagt caggaggtga gagggcgatg tcttacctaa aagaggcttt
    14881 tcaagcaagg ccttctctgt taattttaga tgagccaagc tcttatttag accatgctaa
    14941 tcgtgattgg ttgattaatc aattgaaacg ctaccgagga accttgctgg tggttagcca
    15001 tgatcggtat ttgatcaatc aattgagtca gaaaatatgg ttgcttgagc atcaaacgat
    15061 caagacttac catggcaatt atgatgatta tcagcgttct agacagctag aggaggataa
    15121 gcagctaaga gcttttctgg aataccaacg aaagactaat caactgaaaa aaagcctgac
    15181 cagaaaaaaa gtgcaggcca acaaaatggc tgtaaagaaa aagtcggttt ctcggtcaga
    15241 ttggaaaacc aattcctttg cgggcagcta tgattcacag gccaaggcta tggcaaaagc
    15301 agctaaagct atggaaaatc gactcactcg aatgaaagag gttaacagtc cgcgcaaaaa
    15361 ggcttgggca aaattaaaaa aggatccaaa cgaaggtgca ctaccaaata ctcttttaca
    15421 cctacaagaa ggtaccctta caagggacca tcagttattg tttgactatc ctggtattgt
    15481 gatcagatca catagcagga tagcgattat cgggagaaac aaggctggta aaagcagctt
    15541 tttagatcag ctggcagccc aggccttgtc tggattttat gcgcaaaatc taaggataac
    15601 ctattttaaa caggaccagg ctgacttgga gccggatcag acagcagtag agctcattag
    15661 tcggcagtcc agccaagata gggtcaccat tttaaattat ctagctatga tgggcattga
    15721 ttatgataag gccaatcaaa aggtagctgt cttatctggt ggggaaaggg ttcgtttggc
    15781 gttagtggct gccttgctga cagatcatca gcttttgatt ttagatgagc cgacaattta
    15841 tttggatctt gtcgctattg aggctttgga gtcttgcttg attgactatc cagctgctct
    15901 tttgttggtt tctcatgacc tagcatttgt taacaaggta gcaacagaaa tttatgaggt
    15961 taaggatcat catttaacag cctatcattt tgaagactag caaaaaagcc taggctagct
    16021 tatcctcgct agcttaggct tattagtcta catttcattt ggtgcctcaa cacccaatag
    16081 acgaagcgct tctttgagga cgattgcagt tgcatagcaa agcgctaagc ggttgtcacg
    16141 ttctggatcg tcttcgagga tacgggtatg cgcataatat ttgttaaagc tttgtgccaa
    16201 gtgaatagca aattttgcca tgattgatgg ctcaaagtta tcaaaagcac gcttgatgat
    16261 acgtgggaag tcctggataa gcttaatgat ttcccagctt tcaggatcat taaggctata
    16321 gcttgtatcg gtagctggcg taaagcttgc tttacgcagg atagattgga tacgtgcgtg
    16381 tgcatattgg acgtaaggac cggtttctcc ttcaaaggat accattgctt caagatcgaa
    16441 gtcatagcca ttcatacggt ctgtttttaa atcatagaac ttgatagctc ccacaccaac
    16501 agcatgagct actgcttcct tgttggcaag cttaggattt ttagcttcga tttggtttgc
    16561 tgctctgctg atggcttctg caaccgttgg ctcaagcaaa atgacattac ccttacgtgt
    16621 tgataatttt gcaccgccct ttgtcacaag gccaaaagca acgtgtgtca tgtcatctga
    16681 ccaatcgtag cccatttctt taagaacagc ctttaattgc ttgaagtgtg cagcttgctc
    16741 gttgccaacc acgtaaactg attttgcaaa atcataggta cgcttgcggt aaagggcagc
    16801 agctagatca cgagtaatat aaagcgtagc tccatctgat tttttaatga gagctgggtg
    16861 ctcaatacca tatttttcaa ggttaaccac cttagctccc ttagattcga ctagtaggcc
    16921 tttgtcctca agaagctcaa ggacctcatc cattttatca ttgtagaagg cttcaccatt
    16981 atagctatca aagctaactc ctagctggtc atagagtcgg ttaaactcaa tcaagctttc
    17041 atcgcggaac cactgccaaa gctctgtagc ctcttgatct ctctcctcta gcctgcggaa
    17101 ccattcacgt gcctcctcat caagactagg atcagtttct gcctctgcat tgattctcac
    17161 atagagcttt aagagctcat caattgggtg tgcttgaaca gcggcctcat ttccccactt
    17221 cttatacgct acaatgagca taccgaattg cttgccccag tcacctaggt gattgatttt
    17281 aacaggctta tagcccattt ttgcaaagat atgagcaaga ctgtccccga taactgttga
    17341 gcgcaggtga ccgattgaaa atggcttagc aatgttaggg ctggacatat caatagcaat
    17401 atgacgtcct tgtccttcat cctgttgagc atagtcagct ccgtcagcaa tcacctgtgt
    17461 aagaacctgt gcagaaatgc tagccttatc taaaaagaaa ttgacataag gaccaacagc
    17521 agcaaccttc tcaaattggc tggcgtcaat cctttcagct aaatcactag caatagcttg
    17581 tggtgctttg cgaagcgcct ttgctagact aaaggctgga aaggctaagt ctcccatgtc
    17641 agaatttttg ggtgtttcaa gtaagttaaa aatggcagcc tgctctagtt caggaacaat
    17701 cttagcaatc tcagctgcaa tcagagtttt agtgtccata ttgcttctcc taaaaatagt
    17761 ttgtcaccct attctaacac atttcttgga aataaacgag gtgtctattg agaaattata
    17821 ctagaaggct tgtaggtgtt ttggggaaca aagctaaaga attagagcag caaagcttgc
    17881 caaatctaag ggtctaatga tatgagcaag aaataatgct tccttaaaat aaagcaaatt
    17941 gacagagctg agatgaaata ctaccatttt tttgttataa tttgagagga taattataca
    18001 ttggggagat atatcatgaa taaaatagaa cggcagcagc aaatcaagca acttattcag
    18061 gctgagcaca tcggtacaca ggaggagatt agacggcttc ttcaaaagga tggtatcgtg
    18121 gtcactcagg ctaccctatc acgagattta agagaaatcg gattacttaa attaagagat
    18181 gacagaggta agctatacta tagtctttct gagcctgttg ccacaccatt tagtccagat
    18241 gtgcgctttt atgtcctaaa ggttgaccgg gcgggcttta tgctggttct ccataccaat
    18301 ctgggagaag cagacgtgtt ggcaaatctt attgacaatg atgccattga ggacgttttg
    18361 ggcacgattg cgggtgctga taccttactt gttatttgtc gtgatgagga gattgccaag
    18421 cgctttgaaa aagatttagc tgctggtcta taatatgcct taccgcgaat ccttacatca
    18481 gctgatagca gcactggaaa agcactcaag cattatagct tataaggagg ctcagcagca
    18541 cttgcttcaa aggactgatt ataatcaaaa ggcctatcag atgaagcgac atcaacagga
    18601 cacctatctt tttcgtcaaa tcgctaagga taaagcagct gaagaatcag cttttaaggc
    18661 tcagcaatta cgagaagatt tagatcatca accattgata gatgattatc gtgacaaaat
    18721 gcaaaacgct agtgacttgg ttcggtacat tacagggact atagaagatg aattaaataa
    18781 ggagttcaat gatggcaaag gctaatgttt ctcccggaat gcagcagtat ctggacatca
    18841 aaaaggatta tccagatgct tttttgcttt ttaggatggg agatttttat gagttatttt
    18901 atgaagacgc tgttaaggca gcgcagattt tagaaatcgg cttaaccagt cgtaataaaa
    18961 atgctgacaa cccaattcca atggcaggtg ttccctatca ttctgtccaa caatacatcg
    19021 atgttttaat tgatttgggg cataaggttg ctattgctga gcagatggag gatcctaagc
    19081 aagcggtcgg tgttgttaag cgtgaggtgg ttcaggtcat taccccaggg acagctgtgg
    19141 actcaagcag acctgatagt cccaataatt ttttggtggc tgttgatttt gatggcaagg
    19201 cttatggcct gtcttatatg gacgtctcta caggagaatt ttttgctaca gacctagcag
    19261 attttgccag tgtcaaaagt gagattcaaa acctgaaggc aaaagaggtt cttttaggct
    19321 ttgaattatc tgaagaagag caggctattt tagtaaagca gctgaatctt ttgctgtcct
    19381 ttgagatgac agcactagag gattcgcctt tgattgatca tcagctaaca gcagtcgagc
    19441 tgtctgcagc aggtaagctg ctacactatg ttcatcaaac ccagctgcgt gagcttagcc
    19501 atctacaggc cttggtgcac tatgatatta aggattattt gcagatgtct tatgcaacca
    19561 aatcaagcct tgacctgctt gaaaatgctc gtactggtaa aaagcatggg agcctttatt
    19621 ggttgcttga tgaaaccaaa acagccatgg gtatgcgtct attaagggct tggattgata
    19681 ggccacttgt gactagtgag gcgatcctag aacgtcagga aattatccag gtgtttctta
    19741 atgcttttat cgaaaggaca gatctaagcg atagtttaaa gggtgtttac gacattgagc
    19801 gcttgtctag tcgtgtatct tttggaaaag caaaccccaa ggatctatta cagctaggtc
    19861 atactttggc caaagttcct tatatcaagg ctatcttaga ggcctttaac agtccttacc
    19921 ttgacaagct tgtcaaccaa attgacactt tgcctgagct agagcacctg atacggtcag
    19981 ctatagatcc agatgctcct gctactatca atgaaggcaa tattatcaga acaggctttg
    20041 atgaacggct ggatcattac cgaaaggtca tgcgagaagg caccggctgg attgctgata
    20101 ttgagacaaa agaaagacag gccagtggga taagcaatct caaaatcgac tataacaaaa
    20161 aagatggcta ctattttcat gtgaccaact ctaatctagg tatggttcct gaccattttt
    20221 ttagaaaggc aacattgaaa aattctgagc gctatgggac agcagagcta gctaagattg
    20281 aaggacaaat gcttgaggct agagaggagt catctagcct ggaatatgat attttcatgc
    20341 gtattcgtgc tcaagtggag acctacatcg ataggctgca gcagctagca aaagctctag
    20401 caactgttga tgtcctacaa agcttagcag tggtcgcaga gaagaatcac tatgttcgac
    20461 cattatttaa tcaagagagc aagattgcga ttgacaatgg tcggcatgct gttgttgaaa
    20521 aggttctagg tgttcaggag tatattccaa acagcatttc ctttggtcca cagacaagca
    20581 ttcagctcat tacaggacca aacatgagtg ggaagtctac gtatatgaga cagcttgctt
    20641 tgacagtcat tatggctcag ataggctcat ttgtagctgc agaatctgct agcctgcctt
    20701 tatttgacgc tatttttact aggattggtg cagcagatga tttgatctca ggccagtcta
    20761 cattcatggt tgagatgatg gaggctaatc atgctatcaa gcgagcaacc cctcattccc
    20821 tgattttgtt tgatgagtta gggcgtggta cagcgaccta tgatggtatg gcactagccc
    20881 agtctatcat cgaatacatt catgatagag ttggtgcaaa gactatgttt gcgacccatt
    20941 atcatgaatt gacagagctg tcaaccaagt tgacaaagct ggttaatgtt catgttgcga
    21001 cgttagaaaa agatggaaat gtaaccttcc tgcataagat tgccgaaggt cctgctgata
    21061 aatcctatgg gattcatgtg gcgagaatag ctggattgcc agaggattta ctagccagag
    21121 ctgatactgt gctaaccaag ctggaagctc aatcacaagc aagagagtcc gtcttatcaa
    21181 ctacagaagt aagagagact cagcagctgg ctaatcagca gctatcactt tttacagatg
    21241 atggctcctc tagcgagatt attaaaaggc ttgagagtgt tgatgtgatg aatctaactc
    21301 ccattcaggc catgaccgtt ctttatgagc taaaaaagct actgtaaaag ctagtatcag
    21361 atgttaaagg cacttgtagg ctcaccaggc cacaggtgct ttttggttta ttgaccataa
    21421 gacccttgct agctctgatg cttggctctt ttagttttat gttataatag tccataagaa
    21481 tgcgaggaaa tatatgacaa caattatcga attacctgag gttctcgcca atcaaattgc
    21541 agctggtgaa gtcattgaaa gaccagcaag tgttgttaaa gaattggttg agaacgccat
    21601 agatgcaaag agtagtcaga ttactgttga aatagaagag tctggcttga aaatgattca
    21661 aatcactgac aatggcgaag ggatgtctca cgaggacctg cccctgagcc tgcgtcgtca
    21721 tgccacaagt aaaatcaaaa gtcaaagtga tttgttcaga atcagaacac ttggctttcg
    21781 aggagaagct ttgccttcgg ttgcctctat cagtaaacta acgatcaaaa cagcaacagc
    21841 tgatgcagag catgggtcaa tattagttgc tagtggcggt aagattgagc agctggaagc
    21901 tgtctcaaca cctgttggta caaaaatcaa ggtagaaaac ctattttaca atacaccagc
    21961 tagactgaaa tacatgaaga gcttacaagc ggagctggct catgttgttg atgtcgtcaa
    22021 tcgcttgagc ctggctcacc cagagattgc ttttacattg atcagtgatg gcaagcagct
    22081 aacacaaacc tctggggctg gggatttacg tcaagcgctt gctggtatct atggcctgaa
    22141 tactgctaaa aaaatgattg acatttctag tgctgattta gattttgaag tgggaggctt
    22201 tgtgagtctg ccagagctga caagagctaa tcgtaattac attactatcc tgatcaatgg
    22261 tcgctatatt aaaaatttct tgttaaatcg agccatttta gatggttatg gctctaagct
    22321 gatggtggga cgctttccta tagctgtcat tgatattcaa attgatcctt atctggcaga
    22381 tgttaatgtt cacccaacca agcaggaaat tagaatttct aaggagcgtg aattaatggc
    22441 tctgattagt acagctattt cagagagcct acgagaacaa gacttgattc ctgatgcctt
    22501 ggaaaattta gctaggtcca gcacacgttc attttcaaag cctgagcaga ccagtttgcc
    22561 tttacagcct agtcagcttt attatgatcc gcaaaaaaat gatttcttta ccaaagaaac
    22621 agtggtttca gaggatagcc cgcagggctt taaccatgaa actttggttg acagtggtgt
    22681 caagcaggtt gacaatttgc agctggccaa gactgaatct gaagcagctg ctccaagtgt
    22741 taaatatgct agtcggccag atcctatgct ttctgatggt gagcacccgg gtcttgatgt
    22801 ccacaataag caaaaattat ctcagatgct tgatcgttta gaaaatgaag agcagtcggt
    22861 ctttccagag cttgattatt ttggccaaat gcatgggacc tacctttttg cccaaggcag
    22921 agatggcttg tttatcattg atcagcacgc agctcaggag cgcgtcaagt atgagtatta
    22981 tcgtgacaag attggtgagg ttgacaatag cctacaacaa ttgctggtgc cttatctgtt
    23041 tgagttttcc ggatcagatt ttattaatct tcaggaaaaa atgtcgcttt tgaacgaggt
    23101 tggtatttat ttagagcctt atggcaatca tacctttatc cttagggagc accctatttg
    23161 gatgaaggag gcagagattg aatctggtgt ttatgaaatg tgtgacatgc tgctgttgac
    23221 aaatgaagta tccatcaaaa cttatcgtgc tgagctagcg attatgatga gctgtaaacg
    23281 ttccatcaag gcaaaccata gcttagatga ttattcagca agacagctgc ttttacagct
    23341 tgctcaatgt aaaaacccct ataactgccc acatggtaga cctgttttga ttaacttcag
    23401 caaggcggac atggaaaaaa tgttccgtcg tatccaagaa aatcacacca gcttgagaga
    23461 attgggcaaa tactagagag gatagcatgc gagaattttt ccagttacct aagcaaatac
    23521 aaattcggca atttgtgcgc tttattacca ttacgcttgg cagtagtatc tttcctttta
    23581 tggcgatgta ctatacaagc tactttggcg ccttttggac aggcatacta atgatggtga
    23641 ctagctttac aggctttatt gggaccttat atggaggtca tttgtcagat gctattggtc
    23701 gtaagaaggt aattatgctt ggttcagttg cgagcacctt aggctggctg ctgaccattt
    23761 tggccaatgt tccaaagacg gttcttcctt ggttgacctt tgtgggaatt ttgctggttg
    23821 agcttgcttc cagcttttac gctcctgcct atgaggctat gctgattgat ttaacagatg
    23881 atagcaatcg tcgctttgtt tataccatta attactggtt tattaatata gccattatgc
    23941 ttggtgcagg tatttcagga cttttttatg atcggtattt cttagaactg ttgattgctt
    24001 tactgattat taatatcgtc tgctttggta ttgcctatcg ttattttggt gaaacgaggc
    24061 ctgagcatta ccgctttgag catggtattg gtattctagc aggttttgct aactaccggc
    24121 aagtctttaa ggatcgcgct tttgtgttat ttactatagg gacgatttta tttagcagta
    24181 tttggttgca gatggacaat tacgttccgg ttcaccttaa gctgtatttt gaagagactg
    24241 atgtgctcgg tattcatctg actagctcaa aaatgctgtc actgatggtc tttaccaata
    24301 ccttgctgat tgtgctgttg atgacagtta ttaatcgctt gacagcaagg tggagattat
    24361 taccacagct ggtgatcgga tcggttattt ttgcctttgg tatgctgttg tcatttacat
    24421 ttactggctt ttttgctatt tggtgttcag ttgtggtgtt taccattggt gaaatgctaa
    24481 atgtccctgc caatcaagtg ttaagagcag aaatgatgga tcagtctaaa attggctcct
    24541 acacaggctt tgtctcgatg gcccagcctt tgggagctat tctagcaggt ttgctggttt
    24601 ctcttagtca ttttacagga caggctggtg ttcagctagc atttgttttg attgcctgtg
    24661 tggggcttta tgtgattgtt ttatctgcga aaatgaagaa aaaggtgtag tatgtacgat
    24721 tatattaaag gtcagctaac aaaaattact gcaaagtata ttgtggtaga agcaaatggt
    24781 ttaggctata tgataactgt tgccaatcct tatagcttta cagactgtgt caaccagcag
    24841 gtaacgatct atcttcatca ggtgatcaga gaagatgctc agctgctgtt tggttttcac
    24901 agtgaggaag aaaaggacgt ttttttgaag ctgatttcgg tatcaggtat cggaccgacg
    24961 actgccctag ctattgtagc tgtagatgat aatagaggac tcgtcaatgc cattgataat
    25021 agtgatatta catatttgat gaggttccct aaaatcggaa aaaaaacagc tcagcaaatg
    25081 gtgcttgatt tagcaggtaa gttcgttgaa gcacctaagg aggaaagcag caagccccct
    25141 aaagccaagc aacaggggaa tgaacagctt gatgaggctg tcgaagccct attagccctt
    25201 ggatataagg cgacagagct aaagaaaatt cgagccttct ttgagggaac aagtgagaca
    25261 gctgagcagt atatcaaatc agctctgaaa atgctaatga aaggctagga gcttcatatg
    25321 aaacgttgcg catgggtacc acaagataat aagctttatt gtgattacca tgacttggag
    25381 tggggaaggc ctgtctatga tgatcgcgct ctttttgagc tgctttgtct tgaaagctat
    25441 cagtcaggct tatcttggtt aactgttttg aaaaaacgtc cagccttcag aagtgttttt
    25501 catcattatg atatctcagc tgtggcaagc tttagtgagc aggaaatggc tgctgccctg
    25561 caaaatgcag caattatccg acacaagcca aagctaatag ccactgtcaa caatgcagcg
    25621 gcagtccagc gcatccaaca agagtatggt agcttttcca gctatctttg gaactttgta
    25681 ggaggtcagc caattgacag gcttgtcaac gatgacaacc cagcgcccgc tcaaacagcc
    25741 ctatctctca agctatctaa ggacttgaaa aaacgtggct ttaagtggct aggaccaaca
    25801 actgtttatt cctttatgca ggcagcagga ttggtcaatg accatgaaga gaactgtgag
    25861 tttaggtaga attaatcgcc tctttggagt gatgtttcat gagcctatca aagagagctt
    25921 gataaaaaca gcccaatctt gattgcttat aggatgatgt ataagagcta tgtttttgct
    25981 ccgtacttta aggatagatg atgaatcccc ttatttaccc tgtagcgaat gttgtaagct
    26041 tctaatgggt ttaaggtttt agcctgttac tgctattgcc agtaagctac agtttgatca
    26101 ggtagttata ttggattgcc tcaacgattg tgttgctgct ggctggtgct tctttctata
    26161 acttattttg gtgcatgtga ttgtggctct aaaagttata acagagtatc ggtacgattg
    26221 gtgttacccc ttggtttcta tttttttctt atcagccagt ctggcattta cagcctataa
    26281 taaaagctac cgcttaaaaa tttcttagcg gtagtttttt agttcatgtt gcaaggtttc
    26341 tagaagttca gtttcttctg tcaactgtag taattgtaag cctttattaa ttaggtgatc
    26401 atcattacga caaataccga gacgaacttg ggaaaaacct aagctatcat agcgtttaag
    26461 ctgtctagct aatttgattg ttagtaaggt aatttcttcg cactcctttt tgaggttgtg
    26521 atagaggtaa atggttgaaa gattggttag taaagcatat tcagatgatt tgatattgcg
    26581 gtaatcttta tattttgcta ggctatctag gattttttga ctgatgtttt caattatttc
    26641 gataggaaag tgaaaaagaa tggtatgtag taattgtaaa tctttctcat accaagtatc
    26701 ttgttttacg agggaattcc agattttata agctagctct tgtaaatctt gattgttttt
    26761 aacgcctttt ttcctaagac ttatcatgac tt
//
LOCUS       DARYXS010000019        25877 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.019, whole genome shotgun sequence.
ACCESSION   DARYXS010000019 DARYXS010000000
VERSION     DARYXS010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25877
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.019"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            142..747
                     /locus_tag="TV193_000651"
     CDS             142..747
                     /locus_tag="TV193_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1512874.1"
                     /translation="MGSTLIDESLAFNAFMKQWRISLARCGKQLTREELLSSINMLTA
                     AGICEFDLLWQRLAPKGCQRPKWSHQLERLFADTKPCLQVLSETYQLGIIANQAKGLK
                     ERLERFGISHYFALMISSSDVGLQKPDLALFRYALDQAGVLARDAVYIGDRVDNDIIP
                     AKALGMRAVRIHQGLAASSPDDRLYPSDVHISKLSDLLECF"
     gene            1215..3995
                     /locus_tag="TV193_000652"
     CDS             1215..3995
                     /locus_tag="TV193_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1512875.1"
                     /translation="MSNKKFFTYASLLALIAVPTVVEEVTAQPSAQLVYADELRLSPS
                     TDSSPVTKTDEADQPVAQSVSATEPVEALVIADKESALNPAVLADADGSQPIAVVRAG
                     QEGQPYTVTGKIISAVNGWGGHGFYIQDSQGSGLYIYPGSALGYVTGDVVQLTGTLTT
                     YKGELQLKTITKHHKINGELPTPIAEVTIPELEKASPSTLVKLSNVTVGDISSDKHET
                     SSFKVSDTAGNSVAVRLDNRTGVKTSDLLSKIGKGDVINLTAIHSTFDGKLQLKPFSL
                     EQFEVVKKVVREEEVTPLGRVVKIGQIQGASHTSPLLNQAVTVKEVVVTYPDDATHFY
                     VQDINGDNDKATSDGIRVFAQNAQVQAGDVLTISGTVEEFFGKGYDDRKQTDLTITQI
                     KASKVTKTGTAQVPAPLVLGKDRVAPANIIDNDGFSVFDPEEDAIDFWESLEGMLVAV
                     DNAKILGPMSHKEIYVLPGSSTRVLTNSGGILLPETGYNTDLIPVLFKKGKQTIKAGD
                     SYQGRLAGPVSYSYGNYKVFVDDSSRMPVLVDGQLKPEKTHIKKDLSKLSIASYNIEN
                     FSANPSSTKDEKVRRIAESFIYDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLID
                     AIKALGGPAYQYVDIAPENNADGGQPGSNIRTGFLYQPGRVSLSDKPRGGVNDAVKWV
                     NGELSLSVGRIDPTNPAWNSVRKSLAAEFIFQGHKVVVVANHLNSKRGDNSLYGRVQP
                     VTFKSEERRHVLARLLSQFTKEGASQQANIVMLGDFNDYEFTKTIKLIEEGDMANLVS
                     RHELSDRYSYFYRGNNQTLDNMLVSRNLLGRYEFDMVHVNSPFMEAHGRASDHDPLLL
                     QLSFGKDKPAAPSDQPKKTPAPAATTQASKAGRAQLLPKTGDKTALMVSILGLTAVFS
                     SFSLFRKCQERK"
     gene            complement(4417..4554)
                     /locus_tag="TV193_000653"
     CDS             complement(4417..4554)
                     /locus_tag="TV193_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1512876.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     regulatory      4798..4916
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            4914..5420
                     /locus_tag="TV193_000654"
     CDS             4914..5420
                     /locus_tag="TV193_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEL1512877.1"
                     /translation="MTSFTVRDYVYIALVAALYVVLTITPPLNAISYGMYQFRVAEMM
                     NFLAFYHKKYIIAVTLGCMIANFYSFGLIDVLVGGGSTLIFVSLGVALFKQYQEEYLL
                     NGLLNKAFVYFSLFFATSMITVAIELYFFGAPFFLTWFTTAVGEFASLIIGSMIIDRL
                     SKRINLRQ"
     gene            5517..7475
                     /gene="ligA"
                     /locus_tag="TV193_000655"
     CDS             5517..7475
                     /gene="ligA"
                     /locus_tag="TV193_000655"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEL1512878.1"
                     /translation="MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQ
                     TYPAYILKDSPTQLVGSTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEA
                     EYLAELKIDGLSISLVYEAGVLKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVT
                     IRGEAYMSRQAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQE
                     VGLETADSQQKTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEASREELPYEIDGVV
                     VKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRRDQAPMPIP
                     TACPSCQSQLVHFEDEVALRCINPLCPSLVQRSLEHFASRQAMNIAGLGPAVVEKLYS
                     AGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHIGA
                     KASRLILEAYGDLEALLAVTAEELAQIDGLGLVIGQSLVQYFQQEQAAQLLAELKSAG
                     VNLAYLGQRPDQQAALFGLTVVLTGKLEKLNRTQAMEKLEQLGAKVTGSVSKKTDLVV
                     AGSEAGSKLAKAQQLGIRIEDEDWLLNL"
     gene            7488..8510
                     /locus_tag="TV193_000656"
     CDS             7488..8510
                     /locus_tag="TV193_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1512879.1"
                     /translation="MKKQMRARLIYNPTSGQEIMKKNVAEVLDILEGFGYETSAFQTT
                     AAKHSALKEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDFA
                     RALKVPRGNPVEAAKLIGKNQTIRMDIGRAKKDTYFINISAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDHGIFEGEVSMIFAAITNSVGGFEKIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLIIDGGKHVTDRRVEYIKTSKITIEPQSDKRMMI
                     NLDGEYGGDAPITLENLKNHITFFANTDLISDDALVLDQEELEIEEMVKKFAHEVEDL
                     EQGLEE"
     gene            8519..10819
                     /gene="pulA"
                     /locus_tag="TV193_000657"
     CDS             8519..10819
                     /gene="pulA"
                     /locus_tag="TV193_000657"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEL1512880.1"
                     /translation="MDNAVIVHYHSCKGHYFQLSLWQWRDGKLGKDAYFSRFDSFGAV
                     AYLTYPAPYFLSHAYVIVKDQFWQHQTVDFRIERDYGVPKTEVWLVDGDPTVYYSRQA
                     AVASRHDGRCDVHAFDMAVNSQAFDKRWGFSGWLGFRYQPEETSFRLWAPTAEKVELI
                     LYASTDERASVAKVLPMQRGQQYSPDHHAENTCGVWDISLRGDYNYHAYCYRVYYRRR
                     TFRDTRDPYAIATTANGKRSIVIAPEHLRPQGFSVKQGKEATWRLDNPNQAVIYEMHV
                     RDFSKSETSGVSLANRGKFKGLIETGTRNAFGDSTCFDYVKSLGITHIQLQPVFDHHQ
                     FFDENGDYAYNWGYDPENYNVPAASFTSNPHEPATRILELKEVIQAYHDAGINVIMDV
                     VYNHTYSSRESAFQLTVPDYYYRMNPNGSFQNGSGCGNETASEKEMYRKYMLDSILYW
                     TNEFNIDGFRFDLMGLHDIDTMNLIRQELDKIDPRILVFGEGWDMGVGLAAEQKAKKG
                     NASQMPGIGFINDDQRNAVKGAEVYGSLEKGFVSGAPTEGLVAKSILGSDELVSYCTP
                     SQVINYVEAHDNYNLNDLLWVLNPEDSKQDHVKRVQLASAMTILMQGIYFMQLGQEFL
                     RTKLYPTGQDKELTQADRERAMNSYNAPDNVNQVDWRQVSLERETVAIMKKLIYLKTK
                     TALFSYPSFEQIRQHVYIEHAGENTGFISFTVEDERKYRLIFSSFRNRLQSSANHVII
                     ETNDKRFQDSESMLDELTAMILDITQ"
     gene            10966..12845
                     /gene="glgB"
                     /locus_tag="TV193_000658"
                     /pseudo
     CDS             10966..12845
                     /gene="glgB"
                     /locus_tag="TV193_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
     gene            12912..14051
                     /locus_tag="TV193_000659"
     CDS             12912..14051
                     /locus_tag="TV193_000659"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019785022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEL1512881.1"
                     /translation="MKNGMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVITQYQPLALNNHIGNGSSWGLDGINSGATILQPYSATEGNRWFQGT
                     SHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQTHKANMASLTVAVIDVPLKEA
                     SRFGIMNTDTNDRIVEFEEKPANPKSTKASMGIYIFNWQRLRTMLVDAEKNNIDMSDF
                     GQHVIPSYLESGERVYTYNFKGYWKDVGTIESLWEANMEYIGEENALDSRDRSWKIYS
                     KNHIAPPNFITEDAEVKDSLVVDGSFISGKVNHSILSTNVQVRKGAEVKDSFIMSDVI
                     IGEGARITRAIIGEGAVIGDHVIIDGSKDVQVVGYNEVVGVPNED"
     gene            14041..15174
                     /gene="glgD"
                     /locus_tag="TV193_000660"
     CDS             14041..15174
                     /gene="glgD"
                     /locus_tag="TV193_000660"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEL1512882.1"
                     /translation="MKIDKYSAILGSSIGFAEMKGLTDTRPLANLPFDGKYRLIDFQL
                     SNLANAGVRSIYGIFRGQNIRSVFDHIRSGREWGLNSLLSHYFLGFYNTKEDSKEADK
                     DYYQQILTYLKRSGSDQTIYMSCDILCNIELGQVIHLHNANHRNITVVYKKMPTKAIS
                     KANDILDIDETDTVVDRRSLSEGQEVEKMSAGIYIVNTPWLIEQMEKEAEKENPQKLR
                     FLLRDLIVSEGALGFEYTGYLANIHSVKSYFDANMDMLDPHKFYSLLYANQKVYTRVK
                     NEESTYFDAASEVNNAQFASGSIVKGYVEHSIVSRNCRITSQARVTNSILLPKAVIGE
                     GAVIDYAIIDKSVRVAPGVTIRGSAEEPIVVAKGTEVVEDMIK"
     gene            15171..16601
                     /gene="glgA"
                     /locus_tag="TV193_000661"
     CDS             15171..16601
                     /gene="glgA"
                     /locus_tag="TV193_000661"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEL1512883.1"
                     /translation="MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVSVILPYY
                     DVVDQAFGQQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQGYFFRGRIYGDW
                     DDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVF
                     TIHNIAFQGQFDPGMLGDLFDVGIERYEDGTLRWHDCLNWMKAAVLYADRVTTVSPSY
                     AHEIQTPAFGQGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPASFSAEDLSGKAA
                     TKQALQERLGLPVRADVPLIGMVSRLTDQKGFQLVLEELPHILQQDVQLVLLGTGDPD
                     YEAAFSWFAKAYPEKLSANITFDLPLAQQIYGACDLFLMPSAFEPCGLSQMMAMRYGA
                     IPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTI
                     QQHAMTKDFSWDTASLAYLDLYKSLL"
     gene            16620..19016
                     /locus_tag="TV193_000662"
     CDS             16620..19016
                     /locus_tag="TV193_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEL1512884.1"
                     /translation="MHVTKEQFIRDFKDTLHEEQLIKVPAATAAELFTSLAKLIRKYY
                     TDTWIERNRSLTEQQQKIAYYFSIEFLPGRMLETNLLNLGILDTVKEAFADLGIDFQA
                     VKHAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVNGYQVELP
                     DSWFGSIGNVWEIRKDHDIVDVKLFGNVYLKANQDGKLAPIYEGAQVLRAVPYDVPQI
                     GFENDVINNLRLWDVEIPEEHELDYPTIESRRAVKDITAILYPDDSSYEGKKLRLIQE
                     YFMTSAGIQTIIKSYLKQGLPLTELHQKVSVHINDTHPAVAPAELMRLLIDDYGLEWV
                     DAWATTVKTMSYTNHTILSEALEKWDAELFKTVLPRVYQIILEIDHRFVAEMAQKGID
                     PQIIENTRIVKDNQIYMANLAIIGGYSVNGVAKLHTELLKTDTLKDFYALYPEKFNNK
                     TNGIVQRRWTQIAAPELSAAIDRTIGKGWRKDIHQLRQLSQFTEDPAVLNDFYQVKQA
                     AKQRLARYILEKTGLEVSTEAIFDVQVKRLHAYKRQLLNVLHIMKLYLDLKANPDLDM
                     VPRVFIFGAKAAPGYHFAKSVIKIINELANLINHDTSLKGKLKVVFLENYNVSLAELI
                     IPAADISEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGEENIVIFGMD
                     KDQVYDHYAKHDYYSRGLYESDPQIKAVVDAFVNGTIPNSQHEGMEIYDALITHNDEY
                     FLLEDFSSYVKAQAKIDRLYRQKDRWSKMSLINIAHSDKFTSDDTITQYAKDIWQLKR
                     "
     gene            19358..19555
                     /locus_tag="TV193_000663"
     CDS             19358..19555
                     /locus_tag="TV193_000663"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEL1512885.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKSASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            19589..20305
                     /gene="atpB"
                     /locus_tag="TV193_000664"
     CDS             19589..20305
                     /gene="atpB"
                     /locus_tag="TV193_000664"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEL1512886.1"
                     /translation="MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTL
                     KPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETT
                     SGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            20323..20817
                     /gene="atpF"
                     /locus_tag="TV193_000665"
     CDS             20323..20817
                     /gene="atpF"
                     /locus_tag="TV193_000665"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEL1512887.1"
                     /translation="MSVTIGELIGNFILVTGSVIVLLLLIKAFAWGAIEAVLQARSQQ
                     ISQDIDQAEQARLNAQQLEKEGQANLEASRSEASQIVEAAKETGKAQETRIVAEATEE
                     ADRLKAAALTDIEHSKSEAISAVKTEMSDLTVLLAEKIMGANLDKAAQSQLIDRYLDD
                     LGEA"
     gene            20817..21353
                     /locus_tag="TV193_000666"
     CDS             20817..21353
                     /locus_tag="TV193_000666"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEL1512888.1"
                     /translation="MTKKEQALIEQYAKSLVQVCQERDTLEALQADVLAILEVFKATN
                     LAKTLSSLAVPRAKRLELVRQLQGDNIVYLNNLLEVMLQNEREAYLYQVLLRVLSELA
                     SVSNQYDVTVTSAVPLSEEQKQRVRTVVSKRLAVKTGRLIEKVDPSLIGGFMISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            21369..22874
                     /locus_tag="TV193_000667"
     CDS             21369..22874
                     /locus_tag="TV193_000667"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEL1512889.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGL
                     DNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFESLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDAHYDHLFETIRTTKDLPQEAELDVAIQAFKAQSNFK"
     gene            22892..23767
                     /locus_tag="TV193_000668"
     CDS             22892..23767
                     /locus_tag="TV193_000668"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEL1512890.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSI
                     MDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVG
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVI
                     LEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            23935..25341
                     /gene="atpD"
                     /locus_tag="TV193_000669"
     CDS             23935..25341
                     /gene="atpD"
                     /locus_tag="TV193_000669"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEL1512891.1"
                     /translation="MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKDGDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EAPFADDVNREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSEE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKHDHLPEDAF
                     RAVGPIEDVIEKAKKMGF"
     gene            25354..25770
                     /locus_tag="TV193_000670"
     CDS             25354..25770
                     /locus_tag="TV193_000670"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEL1512892.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINVIAP
                     LQVHEMKIRRVSEDDRVDWVAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AERDIAEAETTHDIDEVRRAKVALRRALNRINVSKK"
BASE COUNT         7219 a         5035 c         6196 g         7427 t
ORIGIN      
        1 ttacaagctt tgattttaaa gcattctagg actgtcctag aatgctttta gttttgataa
       61 gcacaatccg ctgttgactg tataaaccgt atatgataca aaataagagc ttgtagcagt
      121 gaagccacta actctagtgc tgtgggctca accttgattg atgaatccct tgcttttaat
      181 gcgtttatga agcagtggcg tatcagtcta gctcgttgtg gaaagcaatt aactagagaa
      241 gaattactat cctcaatcaa tatgctgaca gccgcaggga tttgtgagtt tgatttgctg
      301 tggcagcgtc ttgctcctaa ggggtgtcag cgtcccaaat ggagccatca gctggagagg
      361 ctctttgcgg atacaaagcc ttgtctacag gtcttgtctg agacttatca gcttgggatt
      421 attgctaatc aggcaaaggg tctaaaagag cgcttagaga ggtttgggat tagtcattat
      481 tttgccctta tgatatcttc ttctgatgtg gggctacaaa agcctgatct tgctctgttt
      541 cgctatgcac ttgatcaagc aggcgtatta gcgcgtgatg ctgtttatat tggggatcgt
      601 gttgacaatg atattattcc tgctaaggca ttgggaatga gagctgtcag gattcatcaa
      661 gggcttgctg cgtccagtcc agatgatagg ctttatccta gtgatgtcca tattagcaaa
      721 cttagtgacc tgttagaatg cttttaacca gtctttagct tgaactagct tttctttgtg
      781 gtctttctgg gtgaatggca gcaagctttg gagtcatgtt atggctagac cttggatcta
      841 agggcgctga gcgtctcata tgatgaggcc gatcaagtag tctccttgac aagtagatta
      901 ttgtttggtg cttataggtg gctttaggtg atgactggtt ttgcctcaac taaggctcgc
      961 tattgctatc tggggtatct tctgactttt ttaatgtgct cttatctggt tggattagac
     1021 ctgctccttg cttgaggaaa gctgttttta acgctgatga gtctgggaaa tggtgagatt
     1081 ggtgttggct tttactagtt tttttgcgtt tacttgggct aactttatat gagaaaaaaa
     1141 gaaaaatatt tattttatct gttatttttg ttacaataag cgtgtaaact aagatgcatt
     1201 aaaaaggagt ttttatgtcg aataagaaat tttttactta tgcttcatta ttggcattaa
     1261 tcgctgttcc tactgtggtt gaagaggtga ctgcacagcc ttcagctcag cttgtttatg
     1321 cagatgagct aaggctatca ccaagtaccg actcatctcc agtaacaaag accgatgagg
     1381 ctgatcagcc agttgctcaa tctgtttctg cgacagaacc agtagaggct cttgttattg
     1441 cggataaaga aagcgcttta aatcctgctg ttctagctga tgccgatgga agtcagccga
     1501 ttgcagtggt tagagctggt caagagggtc agccttatac cgttactggc aaaatcatca
     1561 gtgctgttaa tggctggggt ggtcatggct tttatatcca ggacagtcag ggatcaggtc
     1621 tttacattta tccaggaagt gctttggggt acgtgactgg tgatgtggtg cagctgacag
     1681 gaacactgac tacttacaag ggtgagcttc agcttaaaac gattacaaag catcataaga
     1741 ttaatggcga attaccaaca cctattgctg aggtaaccat tccggagcta gaaaaagcaa
     1801 gcccgtctac cctggtgaag ctttcaaatg tgactgttgg agacatttca tcagataagc
     1861 acgaaacctc ctcttttaag gtcagcgata cagctggcaa tagtgttgcg gtgcgtcttg
     1921 ataatcgtac aggtgttaag acctctgact tactctctaa aattggcaag ggtgatgtga
     1981 ttaatctgac agctattcac tcaacctttg atgggaagct ccagctcaag ccctttagcc
     2041 ttgagcaatt tgaggtagta aagaaggttg ttcgagaaga agaggtgact cctcttggtc
     2101 gagtggttaa aatcggccaa attcaaggtg ccagccacac ctcaccgctc ttgaatcaag
     2161 ctgtaacagt aaaagaggtg gtggtgacct atcctgatga tgcaactcat ttctatgtgc
     2221 aagatattaa tggtgacaac gataaggcga cctcagacgg tattcgtgtc tttgctcaaa
     2281 atgctcaggt gcaggctggt gatgtgctga ccatttccgg aacagtggag gagttctttg
     2341 gcaaaggcta cgatgaccgt aagcagacgg atctgaccat tacgcaaatc aaggcatcta
     2401 aggtcactaa aacagggact gctcaggtac cagctccgct tgtgctaggt aaggatcgtg
     2461 ttgctccagc taatatcatt gataatgatg gctttagtgt ttttgatcca gaagaggacg
     2521 ctattgattt ttgggaatcc ttggagggaa tgcttgttgc cgttgataat gccaagattt
     2581 tagggccgat gtctcataag gaaatttatg tgttaccagg gtcatcaact cgagtgctga
     2641 ctaactcagg tggtatttta cttcctgaga caggctataa tacagacctg attcctgttc
     2701 tctttaaaaa aggaaagcaa accatcaaag ctggtgattc ctatcaggga cgacttgcag
     2761 gtccggtatc atatagctat ggtaattata aggtgtttgt cgatgacagc agtcgtatgc
     2821 cagtcttggt tgatggtcag ctgaagcctg aaaagacaca catcaagaag gaccttagca
     2881 agctaagcat tgcctcatac aacattgaaa acttctcagc aaacccatca tcaacaaaag
     2941 acgagaaggt aaggcgcatt gcagaatcct tcatctatga cctaaatgct cctgatatta
     3001 ttggtctcat cgaggttcag gacaataatg gacctactga tgatggcaca acagatgcaa
     3061 cacaaagcgc tcagcgcttg attgatgcca tcaaggcctt aggtggacca gcttatcaat
     3121 atgtggatat tgctccggaa aataacgctg atggtgggca gccgggcagt aatattcgga
     3181 caggcttcct gtatcagcca ggacgtgtca gcctttctga taagcctaga ggtggtgtta
     3241 atgatgcggt gaaatgggta aatggtgagc taagcttgag tgttggacgt attgacccaa
     3301 caaatcctgc ttggaatagt gttagaaaat cattggctgc tgagtttatt ttccaaggcc
     3361 acaaggttgt ggtggttgcc aatcatttga attccaaacg aggcgacaat tcattatatg
     3421 gacgtgttca gccggtaacc tttaaatcag aggaaagacg tcatgtctta gcaaggcttt
     3481 tgagccaatt tactaaggaa ggtgctagtc agcaggctaa tatcgttatg ttgggtgact
     3541 ttaacgatta tgagtttacg aagaccatta agctgattga agaaggagat atggcaaatt
     3601 tggtgagcag gcatgagctt tctgaccgtt attcttactt ctatagagga aataaccaaa
     3661 cgcttgataa catgcttgtt tcacgcaatt tgcttggtcg ctacgagttt gacatggttc
     3721 atgtgaattc accatttatg gaagcgcatg gacgtgcttc tgatcatgat ccgttgcttc
     3781 ttcagctctc ctttggaaaa gacaagccag cagcaccatc agatcagcca aagaaaacac
     3841 cagcaccagc tgcgacaact caagcctcta aggcaggacg tgcacagcta ttgccaaaaa
     3901 caggtgataa gacagcgctt atggtaagta ttttaggctt aacagctgtc tttagctcct
     3961 ttagcctgtt taggaaatgt caggaaagga agtaaaggat ttctttgggg taggccagca
     4021 gctgagcggc tactgcgttt tgtctgctgg tgctatatag gtggttgaag cgagcgaaga
     4081 gaggtatgct tcctaggatc atagcacaat atcttatgct tataaacgaa cacaatgctc
     4141 cttatgagca ttcaaaacct atactcaaaa ggaatataac agctgagtta agagggattg
     4201 cttttgacag attgtggtaa aaaaagggat cttgaggaat tggctagtga tctagctgcc
     4261 aaaatgcgat gtcttgtttg actatttttc cctattggga tataatgaca atagaaaaag
     4321 ggtagttgtt tgcgcaacta ccctgtgcag aaccgtttaa gacggtggca gaatgaaagt
     4381 taaaaaataa tcgtcgacct accaaagttc agacggttat tttttattgt ttaatatgac
     4441 gattgcaacg actaagctga ttaaggtaag taagaaacta ccaaaagcca gcatgagttg
     4501 aagggcctcg taagtagaca ataaaacgct cctttcagtt ggattttgat gcattgccca
     4561 taggcatcac cacctttcag aaatcagagc caccgtctta gcttttctgt aaagaacatt
     4621 atatcataat cacatgagaa agccgttaga ttttaaactg atcaggcggc tttttggtgt
     4681 tttgctgtct tttagtggaa tcgcctaagc tttgctgtat agtatgggat tttatgcttt
     4741 ttgtaagggc ttaggctgct atggcagggt ccatgtcctt tgtcaatagc ttagttttat
     4801 ggtacaatgt aggcgttgcc tagcaaccct tggtgcttag ttccctttca ccaagcatat
     4861 tacaaacgtg gcggagctgt ttatgctcta gtctgacgtc aaaggagaaa cacatgacaa
     4921 gttttactgt tcgtgactat gtttacattg ctctagtggc tgccctttat gtggttttga
     4981 caatcactcc acctttgaat gctatttcct atggcatgta tcaatttcgg gttgccgaga
     5041 tgatgaattt tttggctttt taccataaaa agtatatcat tgcggtgacc ttgggctgta
     5101 tgattgctaa tttttatagc tttggcttga ttgatgtttt ggtgggtgga ggctcaacgc
     5161 tcatttttgt tagcttaggt gtcgctttat ttaagcaata ccaagaggaa tatctcttaa
     5221 atggcttgct gaataaggcc tttgtttatt tctcactatt ttttgcgact tctatgatca
     5281 ccgttgcgat tgagctttac ttctttggag caccattttt cctaacttgg tttaccactg
     5341 ctgtagggga atttgcttca cttatcattg gctctatgat cattgatcgc ttatcaaaac
     5401 gcattaattt acgacaataa tagtaacatg tagccttccg tttttgggag gctttttatg
     5461 attttcttct agctaggcaa tagcttattt gctatgtttt gtgataaaat aagactatga
     5521 aaaaacgcat aagagaattg actgatctgt taaatcaata ccgtcaggag tattacacca
     5581 atgacgctcc ttctgtatct gatagtgagt atgataagct ttatcgtgag cttgtagagc
     5641 tggagcagac ctatccagcc tatatcctaa aggacagccc cacacagctg gtgggcagta
     5701 cgattttgac aggatttcag aaatatcagc accagtatcc gctctttagt ttgcaggatg
     5761 ctttttcacg tgaagagctt aacgcctttg atcagcggat caaatcagcc tttcctgagg
     5821 ctgaatacct tgctgagcta aaaattgatg gcttgtccat ttcgctggtt tatgaggctg
     5881 gtgttctaaa ggttggagcg acacgtggcg atgggactat tggcgagaat atcactgaaa
     5941 acattaagaa tattaaggat attcccaaac ggctaagtca agcacttgat gtgacgatac
     6001 ggggggaggc ctatatgtcg cgtcaggcct ttaagacgat caatgaagag cgtcaggaaa
     6061 atggtgagcc agaatttgcc aatccaagaa atgcagcggc aggaaccttg aggcagctgg
     6121 atactaggat tgttgccaag cgacagctag caaccttttt gtatcaggag gtaggcctag
     6181 aaactgctga tagccagcaa aagaccttgg agcgcttggc cgatttaggc ttttcggtca
     6241 atagccacta tctgctgtcc tcatcgatga atgacatttg ggactttatc cagagcattg
     6301 aagctagtag agaagagcta ccttatgaga ttgatggtgt ggtggtcaag gttaatcagt
     6361 tggcgatcca agaggaactt ggctttaccg tcaaggcacc acgctgggct attgcttata
     6421 agtttccagc agaagaaaag gaagctgaga ttgtatctgt ggattggacg gttggccgaa
     6481 caggtgtggt cacaccaaca gctaatttga cccctgtgca gctggcaggc accactgtca
     6541 gtcgagcgac cttgcataat gttgattata tcgcagaaaa ggatattcgc attggggata
     6601 cggtggtggt gtataaggct ggagatatta ttccagctgt tttgcgggtg gttgaggcta
     6661 agcgtaggga tcaggctcca atgcccattc ctacagcctg tccttcctgc cagagtcagc
     6721 tggtgcattt tgaggacgag gtagctttgc gttgcattaa ccccttgtgt ccgagcttgg
     6781 ttcaacggag cttggagcat tttgccagtc gtcaggcgat gaatatcgct ggtcttggtc
     6841 cagcggttgt tgaaaagctt tattctgctg gcctggtgca tgatgtggca gatatttacc
     6901 gactaagctt ggaggatttg ctgacgctag atggtatcaa ggaaaagtcg gctgaaaagc
     6961 tcttggcagc tattgaacaa tcaaaggcaa actcagctga aaagctcttg tttggacttg
     7021 gtattcgtca tattggcgca aaggctagtc gtctgatatt agaggcttac ggtgatttag
     7081 aggcgctgtt agctgtaacc gctgaagagc tcgctcagat tgacgggctt ggtctagtga
     7141 tcggacaatc cctggtgcag tattttcagc aagagcaagc cgctcagctg ctagctgaat
     7201 taaaatcagc tggggttaat ctggcttatt taggccaaag gcctgatcaa caggctgcgc
     7261 tgtttggttt aacggtggta ttgacaggaa aattagaaaa gctaaaccgt acccaagcca
     7321 tggaaaagct agagcagctt ggtgctaagg taacaggaag cgtttctaaa aaaacagatt
     7381 tagtggttgc tggcagcgag gcaggctcta agctggctaa ggcccagcag ctgggtatca
     7441 gaattgaaga tgaggattgg ttgctcaatc tttagtgagg taataacatg aaaaaacaaa
     7501 tgagggctcg tctgatttac aatccaacct ctggtcaaga aatcatgaaa aaaaacgttg
     7561 cagaggtgct ggatattttg gaaggctttg gctatgaaac ctctgccttt caaacgacag
     7621 cagctaagca ctcagcctta aaggaagcaa gaagggcagc taaagcaggc tttgacctct
     7681 tgattgctgc tggtggagat ggtacgatca acgaagtagt caatggcatt gctcccctag
     7741 agaaaagacc taagatggcg attattccag caggaaccac caatgatttt gctagggcct
     7801 taaaggtacc aagaggcaat cccgttgagg ccgctaagct gattggtaaa aatcaaacca
     7861 tccgcatgga tataggacgt gctaaaaagg atacttattt tatcaacatt tcagccgcag
     7921 gaagcctgac agagctgacc tatagtgtcc ctagtcagct caaaaccatg tttggctacc
     7981 tggcttatct ggctaaggga gtggagctct tgcctcgagt gagtaatgtt ccggtgaaaa
     8041 tcacgcatga tcatggcatt tttgagggag aggtatcaat gatttttgca gccatcacta
     8101 attctgttgg tggctttgaa aagattgccc cagatgctaa gctagatgat ggcatgttta
     8161 cccttatttt gattaaaaca gccaacctgt ttgaaattgt gcacctgctg cggttgatca
     8221 ttgacggtgg taagcatgtt acggatcgcc gcgtcgaata cattaaaacc agtaaaatca
     8281 ccattgagcc ccaatcagat aagcgcatga tgattaattt agatggtgaa tatggtggtg
     8341 atgcgccaat taccctagaa aacttaaaaa atcacatcac cttttttgca aatactgatt
     8401 tgatttcaga tgatgccctt gtcctagacc aagaggagct ggaaatcgaa gaaatggtca
     8461 agaaatttgc gcatgaggta gaggatttag agcagggatt ggaggaatag ggctagttat
     8521 ggataatgca gttattgttc attatcatag ttgcaaggga cattattttc aattaagtct
     8581 atggcaatgg cgagatggta agctgggcaa ggacgcttat ttttcgaggt ttgacagctt
     8641 tggagcagtt gcttatctca cttatccagc accttatttt ttgagtcatg cttatgtgat
     8701 tgtaaaggat cagttttggc agcatcaaac cgttgatttt cggattgagc gtgattatgg
     8761 ggttccaaag actgaggtgt ggcttgttga tggtgatcct acggtttatt attcgagaca
     8821 ggctgctgtg gctagtcgac atgatggtag atgtgatgtg catgcctttg atatggctgt
     8881 caatagtcag gcctttgaca agcgctgggg ctttagtggc tggctaggct ttcgctatca
     8941 gcctgaggag acgtcttttc gtttgtgggc tccaacagca gaaaaggttg agctcattct
     9001 ctatgcttcg actgatgaga gagctagtgt tgccaaggtt ttgcccatgc agcgtgggca
     9061 gcagtactcg ccagatcatc atgcagaaaa cacatgtggt gtgtgggaca tcagcctaag
     9121 aggtgattat aattaccatg cttattgcta ccgggtttat tatcgcaggc gtacctttag
     9181 agacactagg gatccttatg cgatcgcaac gacagcaaat ggcaaaaggt caattgtcat
     9241 tgcaccggag catttaagac cgcagggctt ttcagtgaag cagggtaagg aggctacctg
     9301 gcgcttagac aatcctaatc aggcggtgat ctatgaaatg catgttcgcg acttttcaaa
     9361 atcagaaacc tcgggcgtta gcttggctaa tcgtggcaaa tttaaggggc tgattgagac
     9421 aggcacgcgc aatgcttttg gagattcaac ctgctttgat tatgtcaagt cccttggcat
     9481 tacgcatatt cagctccagc cggtctttga ccatcatcaa ttctttgatg aaaatggaga
     9541 ttatgcctat aattggggct atgaccctga aaattacaat gttccagcag ccagctttac
     9601 cagtaatccg catgagccag ctacccgtat cctggaatta aaggaggtca ttcaggctta
     9661 tcatgatgca ggcatcaatg tgatcatgga cgtggtgtac aatcatacct actcatcaag
     9721 agagtcagcc tttcagctga cggttccgga ttattattac cgtatgaatc ctaatggctc
     9781 ctttcaaaat ggctctggct gtggcaatga aacggctagt gaaaaggaaa tgtatcgcaa
     9841 atacatgctt gattcgatcc tatattggac caatgagttt aacattgatg gcttcaggtt
     9901 tgatctgatg ggcttacacg atattgacac catgaatctt atccgacaag agctagataa
     9961 gattgaccca aggatacttg tttttggtga gggctgggat atgggagttg gtctggcagc
    10021 tgagcagaag gctaaaaaag gaaatgccag ccaaatgcct ggaatcggct ttattaatga
    10081 tgatcagcgt aatgcagtta agggggcaga ggtctatggg agcttagaga agggctttgt
    10141 atcaggtgca ccgacagaag gacttgtagc caagtctatt ttgggcagtg atgagctggt
    10201 ctcttattgt acgcctagtc aggtgatcaa ttatgttgaa gctcatgaca actataacct
    10261 caatgatttg ctgtgggttt tgaatccaga ggacagcaag caggatcatg tcaaacgggt
    10321 tcagctagct tcagctatga cgattctcat gcaagggatt tactttatgc agctgggtca
    10381 ggaattttta cgaacaaagc tttacccaac aggtcaggat aaggagctga cacaggcaga
    10441 ccgagaaagg gcgatgaatt cctacaatgc acctgacaat gtgaatcagg ttgactggag
    10501 acaggttagc ttggagcgcg aaacggttgc tattatgaaa aaactaatct atctgaaaac
    10561 taaaacagct ttgttttcat acccatcatt tgagcaaatc agacagcatg tttacattga
    10621 gcatgctggt gaaaatacgg gcttcattag ctttacagta gaagatgaaa gaaagtatcg
    10681 attgattttc tctagtttta gaaaccgctt gcaatcatct gctaatcatg ttataattga
    10741 aacaaatgat aagcgctttc aagatagtga gtccatgcta gatgagctga cagcgatgat
    10801 ccttgacatc acacaatagc ctgagtgttc tcaggttatt tttgtttgtt gtcaaggata
    10861 aaagggctgt agttacagtt agcagagacc tattaggacc ttgcttatca tatcgcttag
    10921 cgccttgaaa aagggtttag gagtagggaa agaagaggtg atgggatgga taatgactta
    10981 gcgctttata cctttggcac aggtgagaat tttcacatac aggattatct aggtgttcat
    11041 cggattaaca atgacacagg caccagctat gtctttaggg tatgggcgcc caatgcagag
    11101 gctgtcagct tgattggaga ttttactgat tggcagtcca atccacttga gatgagccga
    11161 aatgaggctg gcgtgtggga ggttaccact agcttgccgc aggaaggaga tatttataag
    11221 tattgggtta ggcgccaagg tggtcagctt gttgaaaaaa ttgatccagt ggcctttcta
    11281 tttgaagcta gaccaggaac gggtgctatt gtcaaaaccc ttccagccaa aaaatggcgt
    11341 gatagcttat ggatgggacg gcgaaagcgt tttggcttta ggcagcgtcc ggttaatatc
    11401 tatgaggttc atgcccattc atggaaaaaa gacgaaaacg caaggcccta tgactttagc
    11461 aagctaaaag aagagctcat tccctatctc aagagcatgc actacactca tgttgagttt
    11521 atgccggtca tggctcaccc cttagatatg agctggggct atcagctgat gggctacttt
    11581 gcctttgagt caacctttgg aagcccagaa gcctttcagg attttgttga ggcctgtcat
    11641 cttaataata ttggtgtttt gattgattgg gtgccgggac attttacaca aaatgatgac
    11701 gccttagctt attttgacgg tacagctacc tatgaatatc aggatcacca tcgtgctcat
    11761 aattatggct gggggcccta aattttgatt tgggtaaaac tcaggtacag tcctttttga
    11821 tttcaagtgc ccttttttgg ctggaggctt atcatgttga cggcattcga gtagatgctg
    11881 ttagcaatat gctttacttg gattatgatc aaggcccttg gactccgaat caatacggtg
    11941 gcaaccaaaa ccttgagggg atagcctttc ttcaaaaatt aaccacagtt atcaaggaaa
    12001 aacaccctga tgtgatgatg attgcagagg aggcgacctc agctacccca ataaccagcc
    12061 ctgttgcaga agggggacta ggctttgatt ataagtggaa tatgggctgg atgaatgata
    12121 ttcttaggtt ttacgaagag gatccttatt accgaaaata cgatttcaat ctcttgacct
    12181 ttagctttat gtattgcttt aaggagcatt acattttacc cttttctcac gatgaggttg
    12241 ttcatggcaa aaaaagcctc atgcataaaa tgtgggggga ccgctacaat caatttgcag
    12301 gcctaagaaa tctttacacc tatcaaatct gccacccagg caagaagctg ctttttatgg
    12361 gatctgagtt tggacagttt ttggaatgga aatacgatca tcaattagag tggcaaaatt
    12421 tagaggacga gctcaatgcc aaaatgcagc atttcacagc cagcctaaat cagctatata
    12481 aggaccatag catgctgtgg caaaatgatg aaacctatga cggcattgat attattgatg
    12541 cagacaataa ggacgaatca gtcttgtcgt tttgtcgtca aaacaataaa ggagagctcc
    12601 tgctttgtgt ctttaacatg acacctgttg aaagaccagg ctttaccata ggtgtgccga
    12661 tagcaggtct ttatcaagaa attttcaata cagagcttga ggcctttgga ggtgtctgga
    12721 aggagcacaa tcccttaacc aacacagtag ccaagaaatg gaagacttat ccgcagacct
    12781 tgagctttac cctgcctgca ctaggagcaa gcatctggaa aatcaagcgt cgtcagaagc
    12841 aataagctat tcattgctta cttagctgtt tcaaccaaaa gaagtcacta cagtcatgaa
    12901 aggataacga aatgaagaat ggaatgttag ccctcatatt agcaggggga caaggaactc
    12961 gcttaggaaa attgacacag agcattgcaa agcctgctgt gcaatttgga ggtcggtatc
    13021 gtatcattga ttttgcccta tccaattgtg ctaactcagg gattcataat gtgggggtta
    13081 tcacccagta ccagcctctt gccttaaata atcatattgg caatggttcg tcatggggct
    13141 tagatggtat taattctggc gctacgattt tacagcccta ctctgcaaca gagggaaatc
    13201 gctggtttca aggaactagc catgctatct atcaaaatat tgattatatt gatagcatta
    13261 accctgaata tgtgctgatc ctgtctggtg atcatattta caaaatggac tatgatgaca
    13321 tgcttcagac gcataaggct aatatggcta gcttgactgt tgctgtgatt gatgttcctc
    13381 taaaggaagc cagtcgattt ggcattatga acacagatac caatgaccgc attgtcgaat
    13441 ttgaagaaaa gcctgccaat ccaaaatcaa ccaaggcttc aatgggtatt tatatcttta
    13501 attggcagcg ccttcggacc atgctggttg acgcagaaaa aaacaacatt gatatgtctg
    13561 actttggtca gcatgtgatt ccgtcttacc ttgagtctgg cgagcgtgtc tacacctata
    13621 actttaaagg ctactggaag gacgtcggaa cgattgagtc tctctgggaa gccaatatgg
    13681 aatacatcgg tgaggaaaat gccctagaca gtcgtgatcg ttcttggaag atttattcta
    13741 aaaaccatat cgctccacca aactttatca cagaggacgc cgaggtcaag gattctctgg
    13801 tagtagatgg cagctttatc tctggtaagg tcaaccattc tatcttgtct accaatgtgc
    13861 aggtaagaaa gggagccgag gttaaggatt cctttatcat gagcgatgtt atcattggtg
    13921 agggtgcaag gattacacga gctattattg gtgagggtgc agtcattggt gatcatgtga
    13981 tcattgatgg cagcaaggac gttcaagtcg taggctataa tgaagtagtg ggggtaccaa
    14041 atgaagattg ataaatattc tgccattcta ggcagctcaa ttggctttgc tgaaatgaag
    14101 gggctaacag acacaagacc attagccaac ctaccctttg atgggaaata ccggctcatt
    14161 gattttcaat tgtccaacct tgccaatgca ggtgtccgta gcatctatgg tatttttcgt
    14221 gggcaaaata tccgctcagt gtttgatcat atcaggtcag gtcgtgaatg ggggcttaat
    14281 tccttactaa gtcattattt ccttggcttt tataacacca aggaggattc taaagaggct
    14341 gacaaggact attatcagca gattttgacc tatttaaagc gctcagggtc agatcagacc
    14401 atttacatga gctgtgatat tctctgcaat attgagcttg ggcaggttat tcatctgcac
    14461 aatgccaacc atcgcaacat tacggttgtc tacaagaaaa tgccgaccaa ggccatctct
    14521 aaggctaacg atattttaga tattgacgag acagatactg ttgttgacag gcgaagtctg
    14581 tctgaggggc aggaggttga aaaaatgtca gcaggcattt acatcgtcaa taccccatgg
    14641 ttaattgaac agatggaaaa agaagccgaa aaagaaaacc ctcaaaagct acgcttcctc
    14701 ttacgtgatt tgattgtgtc agagggcgct cttggctttg aatatactgg ctatcttgcc
    14761 aatattcact ctgttaaatc ttattttgat gccaatatgg acatgctgga tccgcataag
    14821 ttttattcac tattatatgc taatcagaag gtctacacgc gtgtcaaaaa tgaagagtca
    14881 acctattttg atgcggcttc tgaggtgaac aatgcccaat ttgcttcagg aagcattgtc
    14941 aagggctatg tcgagcactc aattgtctct cgcaattgtc gcattacctc acaggcacgt
    15001 gttacaaata gtattttatt gccaaaggca gtgattggtg agggtgctgt cattgattat
    15061 gctatcattg ataaatccgt aagggttgca ccaggtgtta ctattagagg aagcgctgag
    15121 gagccaatag ttgttgccaa ggggactgag gttgttgagg atatgataaa atgaagataa
    15181 tgtttgttgc agcagaggga gctccctttg ctaagacagg tggcctaggc gatgtcattg
    15241 gggcattgcc taaatcactt gttaaaaatg gtcatgaggt gtctgtgata ctgccttatt
    15301 atgacgtggt tgatcaagcc tttggtcagc aggttgagga cgtcttgtat ttttatacgc
    15361 aggttggctg gagacgccaa tacgtgggca ttaaaaagct tgtcaaggat aaggtgacct
    15421 tttactttat tgacaatcaa ggttatttct ttagaggcag gatctatggt gattgggacg
    15481 acggtgagcg ctttgcctat ttccagctgg ctgccataga agcaatggag aaaatcgggg
    15541 ttattccaga tattttgcat gtgcatgatt accataccgc tatgattcct ttcctattga
    15601 aagaaaaata ccattggatt caggcctatc aagcgattcg gacagttttt accattcata
    15661 atatcgcatt tcaagggcag tttgatcctg gcatgctagg cgatttgttt gatgttggta
    15721 tagagcgcta cgaggatggc accctgcgtt ggcatgattg cttgaattgg atgaaagcag
    15781 cagtcctata tgcagatcgg gtaaccactg tctcaccctc ttatgcgcat gaaattcaga
    15841 caccagcctt tggacaaggc ttggatcaag tcatgcgaat ggaggcaggc aagctatcag
    15901 gcattgtgaa tggtattgac actgacttat ttaacccagc aagggatcct catttgcctg
    15961 cttcattttc agcagaagac ctatcaggca aggcggctac taaacaggcc ttgcaggagc
    16021 ggttaggatt accagtcagg gcagatgttc cattgattgg tatggtttcg cgcttgacgg
    16081 atcaaaaggg ctttcagctt gttcttgagg aattaccgca tatcttgcag caggacgttc
    16141 agcttgtctt gttaggaaca ggtgaccctg attatgaggc tgccttttca tggtttgcca
    16201 aggcctatcc agaaaaactg tctgctaata ttacctttga tctgccatta gctcagcaga
    16261 tttatggggc ctgtgatctc tttttaatgc caagtgcttt tgagccctgc ggactttcgc
    16321 aaatgatggc tatgagatat ggcgcgatac cgattgtcca tgagatcggc ggcttgaagg
    16381 atactgttgc ctcctacaat gcttatgaaa agactggaac tggttttggc tttgatcagt
    16441 tttcaggatt ttggttaacg cagacgctct tgtttgccct tgatatttac cataaccaca
    16501 aggaggattg gcagactatt caacaacatg ccatgaccaa ggatttttca tgggatacag
    16561 ccagtctggc ctaccttgat ttatataaaa gcttactata acacagaaaa ggaatgggaa
    16621 tgcacgtcac aaaagaacaa tttattcgag attttaaaga taccttacat gaggaacaat
    16681 tgatcaaggt tcctgccgca acagctgctg agcttttcac ctcattagca aagcttatcc
    16741 gtaaatacta tacagatact tggattgaaa ggaatcgttc cttaaccgaa cagcagcaaa
    16801 aaattgccta ttatttttcg atcgaatttt taccaggaag aatgctagaa acaaatcttc
    16861 ttaatttagg cattcttgat acagttaaag aagcctttgc tgacttggga attgattttc
    16921 aagcagtgaa gcatgcagag cacgacatgg ctctaggcaa tggaggtcta ggacgtttgg
    16981 cagctgcctt tatggattcg ctagcgacaa caggctatcc aggctttgga aatgggctgc
    17041 gttatcgtta tgggctgttt aagcaacgga ttgtgaatgg ttatcaggta gaattaccag
    17101 attcttggtt tggctctatt ggtaatgtct gggagatcag aaaggatcat gacattgtag
    17161 acgtcaagct ctttgggaat gtttacctaa aagccaatca ggacggtaag ctagcgccaa
    17221 tctatgaggg agctcaggtt ttgagagctg ttccctacga tgttcctcag attggctttg
    17281 aaaatgatgt gattaacaat cttcgcctct gggacgtaga aatcccagaa gaacatgagc
    17341 ttgattaccc aaccatcgag tcaagacggg cagtcaagga cattactgcc attttgtacc
    17401 cagacgacag cagctatgaa ggcaaaaagc ttagattgat ccaagaatat ttcatgacca
    17461 gcgcaggcat ccaaaccatt atcaaatcct atttaaagca gggcttgcca cttactgagc
    17521 ttcatcaaaa ggtatctgtt catatcaatg atacccaccc agcagtagct ccagcagagc
    17581 ttatgcggct cttgattgac gactatggct tagaatgggt agacgcctgg gcgacaaccg
    17641 taaaaaccat gagctatacc aatcatacga ttttgtcaga agccttagaa aaatgggacg
    17701 cagagctctt taagactgtg ctgccccgcg tttatcaaat cattttagag attgatcatc
    17761 gctttgttgc tgaaatggcg caaaagggta ttgatcctca gatcattgaa aacactagaa
    17821 tcgttaagga caaccagatt tatatggcta atcttgccat tattggtggc tattcggtca
    17881 atggcgttgc caagctacat acagagttgt taaagacaga tacccttaag gacttttatg
    17941 ccttgtatcc tgaaaaattc aacaacaaaa ccaatggtat cgtgcaaaga cgttggacac
    18001 agattgctgc gccagagcta tcagcagcta ttgaccgcac gattggcaaa ggctggcgca
    18061 aggatattca ccagcttcga caattgagtc aatttacaga agatccagct gtgctaaatg
    18121 atttttatca ggtaaaacaa gcagctaagc agcgcctagc caggtatatc ctggaaaaaa
    18181 caggtcttga ggtttcaaca gaggctattt ttgatgtgca ggtcaaacgc ctacatgcct
    18241 acaagcggca gctcctgaac gtcctgcata ttatgaagct ttaccttgat ttgaaggcta
    18301 atccagattt agatatggtg cctagagtct ttattttcgg cgcaaaggct gcaccaggct
    18361 atcattttgc caagtcggtg atcaaaatca tcaatgagct ggctaatctc attaaccatg
    18421 ataccagtct caaaggaaag ctaaaggttg tttttcttga aaattataac gtgagtctag
    18481 cagagctcat tatccctgcg gcagatattt cagagcagat ttcactggcc tccaaggaag
    18541 cctcaggaac atcaaacatg aaatttatga tgactggtgc tatcacccta gcgacccttg
    18601 atggggcaaa cattgaaatc aaagacgagg tcggagagga aaacattgtg atctttggta
    18661 tggataagga tcaggtctat gaccactatg ccaagcatga ttattattca agaggcctat
    18721 atgagagcga ccctcagatt aaagcagtag tcgacgcttt tgtcaatggc accattccaa
    18781 atagtcaaca cgaaggtatg gaaatctatg atgccctaat cacgcataat gatgaatact
    18841 tcttgctaga agacttttct tcctatgtaa aagcacaggc taagattgat cggctctacc
    18901 gccaaaagga tagatggtca aaaatgtcgc tcatcaacat tgcccattct gacaagttta
    18961 catcagatga taccatcacc cagtatgcca aggacatttg gcagctaaaa cgctaatcca
    19021 tcaaggaaga aaaagcatta gttaccttag attgaagaga gtgtcttttg agaccatttt
    19081 cttcaatctt ttttgattgc aaaagacctt gggaatcaga tcagctgcct gcctaatact
    19141 ttggcctatc aaggtatttt ggaatttgtt aatctttttg ttataatagt ggtgtgaagc
    19201 tattttttaa atgaaaaagc caacacttca agatggtgtt aaagtaaggt tagtattagt
    19261 ctaagaaagc gtaaccacat taaagaaagc tgttgacatt ctcaatttta aggaatagaa
    19321 taacaaagta aaaaattttt aaaaggagta ttctattatg aatcctattt tcgcattggc
    19381 tcttgcctgc tttggtgtat cacttgccga aggctttttg atggctaatc tctttaaatc
    19441 agcgtcacgc caaccagaaa ttatcggtca attacgttcc ttgatgatcc taggtgttgc
    19501 ctttattgaa ggtaccttct tcgttaccct tgttatggcc ttcattctaa aataacagcc
    19561 tatttgatat agaaaaggag ggtattaaat ggaagaagct aaagtaccga tggtagagct
    19621 tggtccaata acctttaatt tgaccctact tgctgtttgt attgttacta tcctactgat
    19681 atttggcttt gttttttggg caagtcgtca gatgacatta aaaccaaaag gcaagcaaac
    19741 tgcgttagaa tatttaatca gctttgttaa tggtattggg gaagagcatt tggatagtca
    19801 tcttcagaag tcttattcgc ttttactttt taccattttt ctttttgtgg cagttgccaa
    19861 caacttgggc ttatttacaa agctagaaac aaccagtggc tacaacctat ggacatcgcc
    19921 aacagctaat ttggcctttg acctagccct atctctgttt gtgacgcttc ttgttcatat
    19981 cgaaggcatt agacgtcgtg gttttggcgc ttatttaaaa cgctttgcga caccttggcc
    20041 aatgactccg atgaacctat tagaagaatt taccaacttc ctatcacttg ctatcaggct
    20101 gtttggtaat atctttgcag gagaggttgt gacaggcttg attgttcagc tggccaatta
    20161 tcgcctgtat tggtggccaa ttgctttcct tgttaatata gcatggacag ccttttccat
    20221 atttatttcc tgcatacaag cctttgtatt tacaaaatta acagcaacgt atttaggaaa
    20281 aaaagttaat gaatcagaag aataagaagg gaggacaaac gaatgtcagt tacaattggt
    20341 gagctcattg ggaattttat tctggtaaca ggctctgtca tcgtcttgtt gctcttgatt
    20401 aaagcctttg cttggggtgc tatcgaagct gttttacagg cacgctcaca gcaaatttca
    20461 caggatattg accaagcaga gcaggcgcgt ctcaacgccc agcagcttga aaaggaaggt
    20521 caagccaatc tagaagccag cagatcagag gctagtcaga ttgttgaggc agccaaagaa
    20581 actggtaaag cacaggagac acgcattgta gcagaggcta cagaagaggc agatcgccta
    20641 aaagcagcag cgttgacaga tatcgaacac agcaagtcag aggctatttc agccgttaag
    20701 acagaaatgt cagatttgac agttttacta gcagaaaaaa ttatgggagc caatcttgat
    20761 aaggcggctc aaagccagct tattgatcgc tatcttgatg atttaggaga ggcttaatga
    20821 ccaaaaaaga acaagctctt atcgagcaat atgcaaaaag tcttgtgcag gtctgtcagg
    20881 agcgagacac tcttgaagca ctgcaggctg atgtgcttgc cattttagag gtttttaaag
    20941 ctactaatct tgctaagaca ttgtcaagct tagcggttcc acgtgctaaa aggcttgagc
    21001 tagtaaggca gcttcaagga gataatatcg tttatctgaa taacttgcta gaagttatgc
    21061 tgcaaaatga gcgtgaagct tatttatatc aagtgcttct aagggtttta tccgagctgg
    21121 ctagtgtctc aaatcaatat gacgtgacag ttacatcagc agttccttta agtgaggagc
    21181 aaaagcagcg tgtgcgtaca gtggtttcaa agagacttgc agtaaagaca ggtcgcttaa
    21241 tcgaaaaggt agatccttct ttaattggag gatttatgat tagcgtcaat aataaggtaa
    21301 ttgatacaag cattcgtcgt caattacaag catttaaaat gaatttaaaa tagaaagtgg
    21361 tgtgactttt ggcaattaat gcacaagaaa ttagcgcttt aattaaaaag caaattgaga
    21421 acttccagcc aaatttcgat gtcacagaaa ctggagttgt tacctatatt ggtgatggga
    21481 ttgcacgtgc tcgtggctta gacaatgcga tgagtggcga gcttcttgaa ttttcaaatg
    21541 gtaccttcgg tatggctcaa aacctagagt caaacgatgt tggtatcatt attcttggtg
    21601 atttttcaac gattcgtgag ggtgatgaag tcaaacgtac cggtaaaatt atggaagtgc
    21661 cagtcggtga agctctcatt ggacgtgtgg tcaatccact tggtcagcct gttgatggct
    21721 taggtgacat tgagacaact ggctttaggc ctgttgaaac tccagctcct ggtgttatgc
    21781 agcgtaagtc tgtttttgag tccttacaaa ccggtctaaa ggctattgat gctttggttc
    21841 cgatcggtcg tggccagcgc gagctgatta tcggtgaccg tcagacaggt aagacgtctg
    21901 tagccattga tgccatcttg aatcaaaagg ggcaggacat gatttgtatc tatgtcgcta
    21961 ttggtcaaaa ggaatcaaca gttcggacac aggttgaaac cctacgtcgt tatggtgctt
    22021 tggattatac cattgttgta acggcttctg cttcacagcc atcacccttg ctgtttattg
    22081 caccttatgc tggtgttgcg atggcagaag agtttatgta caatggcaag cacgttttga
    22141 ttgtttatga tgacctgtct aagcaggcgg tagcttatcg tgaattgtcg ctcttgcttc
    22201 gtcgcccacc aggtcgtgag gcctatccag gagatgtttt ctacctgcat agccgcttgc
    22261 ttgagcgctc agctaaggtg tctgatgact taggtggtgg ctcaattaca gccttaccat
    22321 ttattgagac gcaggctggg gatatctctg cctacattgc gacaaacgtg atttcgatta
    22381 cagatggtca gattttcttg caagaggatc tctttaactc aggaatccgc ccagctattg
    22441 atgctggctc gtcagtatct cgtgtcggtg gctctgcaca gatcaaggct atgaaaaggg
    22501 ttgcagggac tttgcgtctt gacctagcct cttatcgtga gttagaagcc tttacacaat
    22561 ttggctcaga tctagatgca gcaacgcaag caaaattaaa tcgtggtcgt cgtactgttg
    22621 aaatcctaaa gcagccactg cacaagccct tgcctgttga aaagcaggtg gtcattttgt
    22681 acgctttgac gcatggattt ttagatgatg ttcctgtaga tgatatttta gcctttgaag
    22741 aagcacttta tgactacttt gatgcgcatt atgatcactt atttgaaaca atccgtacaa
    22801 ccaaagacct tccgcaggag gctgagctgg acgttgctat tcaggccttc aaagcacagt
    22861 caaactttaa ataaaagagg ggggtactag tatggcaggc tctctaagtg aaattaaggc
    22921 taaaatcatt tcaaccgaaa aaacaagcaa aatcactagc gccatgcgta tggtttcttc
    22981 tgcaaagctt gttaaatctg agcaagcagc tcgtgatttt caaatctatg cttcaaagat
    23041 tcgtcagatt acaacagact tactgaaatc agacctgaca acaggctcag ataatcccat
    23101 gctggtgtct cgtcctgtga aaaagacagg ctatattgtt attacctctg ataaaggact
    23161 ggtcggtggt tacaattcaa aaatcttaaa gtccattatg gacatgattc aggaatacca
    23221 tgccgctggc gattatgaga ttatctcaat tggcagcatc ggctcagatt tttttaaggc
    23281 cagaggtatg aatgttgcct ttgagctgcg cggcctagca gatcagccaa gctttgatca
    23341 ggtcggaagg attatctctc agtctgtagg tatgtttgtc aatgagattt ttgatgagct
    23401 gtacgtctgc tacaatcacc atgtcaatag cttgacgagc caggttcggg ttcagcgcat
    23461 gctgccgatt tctgatttgg ttgccgagga ggccgcagaa gaaggtgtca ctggatttga
    23521 attagagcca aaccgtcatg tgattttgga gcagctgctg ccgcaattta ctgaaagctt
    23581 aatttatggt gcgattattg atgcaaaaac agcagagcat gctgctggca tgactgcaat
    23641 gcagactgcc actgacaatg ccaagcatgt gatcaatgat ttgaccatcc agtacaatcg
    23701 tgcgcgtcag gcggccatta cacaagaaat tacagaaatt gtagctggtg ctaatgcact
    23761 tgaataagct tattgtatgc tgatagcgct ctagcagaga cctattagca cttaatgtca
    23821 tcttcaaagc tagatgacat ttgggattaa tgagctaggg gccttttacc cttagctact
    23881 cgaatttaga aaaattcagc ttaatcccct actatcgaat ataaggagaa aaacatgagc
    23941 tcaggcaaaa ttgctcaggt tgttggtcca gttgtagacg ttgtgtttgc gagtggggac
    24001 aaactaccag agattaataa tgcgttgata gtttataaag atggcgataa aaagcaaaaa
    24061 atcgttctcg aggttgccct agagcttgga gacggtatgg tacgtacaat tgctatggaa
    24121 tcaaccgatg ggcttacacg tggattagag gttcttgata ctggtcgtgc cattagtgta
    24181 ccagttggta aagagactct aggtcgtgtt ttcaacgttc ttggtgaaac catcgaccta
    24241 gaagcaccat ttgcagatga tgttaatcgt gaaccgatcc ataaaaaagc accagccttt
    24301 gatgaattgt caacatcatc agaaattctt gaaacaggta tcaaggttat tgacctgctt
    24361 gccccttact taaagggtgg taaggtcggt cttttcggtg gtgccggagt tggtaaaacc
    24421 gttcttatcc aagaattaat ccacaatatc gctcaagagc atggtgggat ctcggtattt
    24481 accggtgttg gtgagcgtac gcgtgaagga aatgaccttt actgggaaat gaaggaatca
    24541 ggcgttattg aaaaaacagc catggttttt ggtcagatga atgaaccacc aggagcccgt
    24601 atgcgtgttg ccttgaccgg cttgacaatt gctgaatatt tccgcgatgt tgaaggccaa
    24661 gacgtcctgc tcttcattga caatattttc cgctttactc aagcaggctc agaggtatca
    24721 gcccttctag gtcgtatgcc ttcagccgtt ggttaccagc caacacttgc cactgaaatg
    24781 ggacaattgc aagagcgtat cacctcaacg aaaaaaggct ctgttacctc tatccaagcc
    24841 atctacgtgc cagctgatga ctacactgat ccggcgccgg caacagcatt tgctcacttg
    24901 gattctacaa ctaaccttga gcgtaagctg acgcagatgg ggatttaccc agcggttgat
    24961 ccactggctt caagttcacg cgcgctgtca ccagaaattg ttggtgagga gcactatgca
    25021 gtagccacag aggttcagcg tgtcttgcag cgctatcgtg aattgcagga tatcattgct
    25081 atcttaggta tggacgagct gtcagaagag gaaaagacat tggtaggacg tgcgcgtcgg
    25141 attcagttct tcttatcgca aaactttaac gtcgcagaac agtttacagg ccttcctggc
    25201 tcttatgttc cagttgccga aaccgttcgt ggcttcaagg aaatcctaga aggaaagcat
    25261 gaccaccttc cagaagacgc ctttcgtgct gttggaccaa ttgaggacgt gatcgaaaaa
    25321 gctaagaaaa tgggctttta gtgaggtgat gccatgacac aaatgactgt tcaggtggtt
    25381 acgccagatg ggatcaaata tgatcatcat gctaagttca tctcagtaac gacaccagat
    25441 ggtgagatgg ggatcttacc taaccacatc aatgtgattg ctcctttaca ggtgcatgaa
    25501 atgaagattc gtcgtgtcag tgaagacgat cgcgttgatt gggttgctat caatggtggg
    25561 atcattgaga tcaaagacaa cgtggttacc attgttgcag attcagccga acgtgatcgt
    25621 gatattgatg ttagccgagc agagcgggca aaattgcgag cagagcgtga cattgcagag
    25681 gctgaaacca ctcatgatat tgatgaggtg cggcgtgcta aggttgcttt gcgacgtgcc
    25741 ttgaaccgca tcaatgttag taaaaaatag taaaatgagt ctaacctacc aatttaacca
    25801 agacagagcg agtagcgctg cttaggaaag ggtgtagata gactctttta tctttttata
    25861 gaaaaaatac cctcttt
//
LOCUS       DARYXS010000020        25284 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.020, whole genome shotgun sequence.
ACCESSION   DARYXS010000020 DARYXS010000000
VERSION     DARYXS010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25284
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.020"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(120..1379)
                     /locus_tag="TV193_000671"
     CDS             complement(120..1379)
                     /locus_tag="TV193_000671"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1512893.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDVVTLDGV
                     PAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
                     DTISVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIE
                     GVERLHGTRHQVIPDRIEAGTYIALAAAVGSGVRITNVLYEHLESFIAKLEEMGVRMT
                     VEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRTEGRGSIIDTIYEKRVN
                     HVPELARMGADIAILGSQIVYHGSNRLSGAQVKATDLRAGAALVIAGLMAQGKTEISN
                     IEFILRGYANIIDKLTALGADIQLIED"
     gene            complement(1695..2900)
                     /locus_tag="TV193_000672"
     CDS             complement(1695..2900)
                     /locus_tag="TV193_000672"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL1512894.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALEAREGQSDDFNAIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLA
                     TLRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQV
                     IKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSE
                     SILEAAVRQVFDLRPAGIIKMLDLKRPIYRQTAAYGHMGRTDIDLPWEQLDKVSPLTE
                     AVAALSEGA"
     gene            complement(3233..5452)
                     /locus_tag="TV193_000673"
     CDS             complement(3233..5452)
                     /locus_tag="TV193_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1512895.1"
                     /translation="MKSKKLMLMASLFMACHLTLTACQSTKQPTNQPKTKQTAKKATK
                     KKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYA
                     DLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
                     RHGDHYHYILKSSLGGQVAYPVPNHVPLSAPSSPSGKFAGVDYPTSDGFLFDGTGIVG
                     RTSYGLIVDHNGHNHLVTYESLRNSKWKHLIEQPKEEAPAKPQSDLEKTIALKKAYLA
                     KSLNIPEDSIRVEHTEEGIILDYPHGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGM
                     ATLRKLGFDEEVISSIIHANAPTEFPSRERDLEKMKAWLATVEYLNIGEIKDPLKRAG
                     LNLMPNIQILGIGFTPITDITPVYQFKNLKQLWMTQTGIKNYDFLKNLPTLEGIDISQ
                     NGVSDLSFLKAFPHYKVISAAGNDITDISILKELPNLESVNLDFNKITDLSALANAQK
                     LVAVSLEHNQIKDLSALSNKGQLTKLFVSNNPDLDLSTLKSSALKEITAKEVNLQSLS
                     FVKDLPALEQLVVDQNKLNSLTGLEHNKSLIQLSANQNMINSLALPGTQSSLQSLNLE
                     ENQLTNFEGVNNYLALEAINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAESG
                     QFPQGIIKNFKAAEGGSLNNATPAEAVEDEHKPADTDQEAADKHDHEHHDHDEHHHG"
     gene            5979..6920
                     /locus_tag="TV193_000674"
     CDS             5979..6920
                     /locus_tag="TV193_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEL1512896.1"
                     /translation="MKTSEKIYQLLACSDDYVSGEYLAEQLKLSRTSVWKSIKSLESQ
                     GLHIESLKHKGYRLIQGDILLPELISQELNMPLSYHEKSQSTQLDAKQGIELKHTAPR
                     LYLAPSQYAAKGRLNRQFFASPHGGIYMSLHLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTQIKWVNDIYLGHKKIAGILTEAITSVETGVITDVIIGVGLNFFVTEFSENLK
                     ERAGSLFSNKPSITRNALIIDIWKLFTTIPIKDHIKVYKEKSLVLQKQVSFQENDRQK
                     TATAIDLTDEGHLIVQLDNGQLQVLRSGEISLSSWGD"
     gene            complement(6895..7098)
                     /locus_tag="TV193_000675"
     CDS             complement(6895..7098)
                     /locus_tag="TV193_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 family protein"
                     /protein_id="HEL1512897.1"
                     /translation="MTIRQFMFMAFICAFEAYFFSDLLFSGDYIFALFWGLLLFRDLR
                     RAYAIDQFTKNIINAVNPPRKKD"
     gene            complement(7479..9155)
                     /gene="dnaX"
                     /locus_tag="TV193_000676"
     CDS             complement(7479..9155)
                     /gene="dnaX"
                     /locus_tag="TV193_000676"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEL1512898.1"
                     /translation="MYQALYRKYRSQTFAEMVGQSVISTTLKQAVESEKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVKGEPCNHCDICRDITTGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPSDNVVFILATTELHK
                     IPATILSRVQRFEFKAIKQPAICEHLAAILDKEGIAYEIEALHLIARRAEGGMRDALS
                     ILDQALSLSFDNRVTLAIAEEITGSISISALDDYVQHLIRQKTSQALANLETIYDSGK
                     SMSRFATDLLTYFRDLLIVKSGGDHHRQSALFDDNLAVSFDQLFTMIATVTKHLPEIK
                     KGTHPRIYAEMMTIQLAEQGQAADTAIPSSLLADVDDLKHEISQLRETISQLQAQKGL
                     TAQATPAHSIKPKAFTYKVDREKILKIMEETVQDSQQSRQYLEALKSAWNEILDSISA
                     QDRALLLGSEPVLANSENAILAFEAAFNAEQAMKRQDLNDMFGNIMSKAAGFSPHILA
                     VPKADFHHIRSEFAMTIKTKKETAKESEQATFDMPEGFDFLTDKIHLIED"
     gene            complement(9155..9652)
                     /locus_tag="TV193_000677"
     CDS             complement(9155..9652)
                     /locus_tag="TV193_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEL1512899.1"
                     /translation="MNKTTKIEHYQLLLAQAKALFSNESNALANLSNASALLKMTLPH
                     SVFAGFYLFDGQELILGPFQGKVSCVHIKLGKGVCGESAQSGQTIIVDDVKKHANYIS
                     CDSAAMSEIVVPMLKAGRLVGVLDLDSSLVADYDQIDQDYLEQFVALLLENTSFRFDM
                     FGVEN"
     gene            9832..10602
                     /locus_tag="TV193_000678"
     CDS             9832..10602
                     /locus_tag="TV193_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEL1512900.1"
                     /translation="MLLVFNGIEYECLNLVSPKQTFYQSAALILSTSLLGIYLIPFSL
                     AIAYLKRIYQIRISTLLLAGLGGLYISGFLASFGNQVLEQFWISLIKPNIALEEWTGA
                     LTGPFVEEPIKAFAAMLVIYLLPAINLKQKLVISLISGMGFQLTEDISYIASAADRSI
                     NDILPTTLARISSSPNSHWVYTGIFTMGAYLLIKKSQLFPRSLQIFWVVSPLALHFIW
                     NSPISDLAGVAVIHGTITTLIFISLFKKIHALDDSIAY"
     gene            complement(10784..11056)
                     /locus_tag="TV193_000679"
     CDS             complement(10784..11056)
                     /locus_tag="TV193_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEL1512901.1"
                     /translation="MLPSLILLFGWNAVVFAAYGSDKHRAQKGQWRLSEKMLLTLSLL
                     CGGIGAYLAGHYFNHKTKKWYFVLSWYMGILMTLVLCYYLYQWYIL"
     gene            complement(11079..11705)
                     /gene="udk"
                     /locus_tag="TV193_000680"
     CDS             complement(11079..11705)
                     /gene="udk"
                     /locus_tag="TV193_000680"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEL1512902.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYK
                     DQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQ
                     EPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL"
     gene            11801..12895
                     /locus_tag="TV193_000681"
     CDS             11801..12895
                     /locus_tag="TV193_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1512903.1"
                     /translation="MITNLPTQWQEKLAKLGFTNLTPIQEQVFQPIVDGKSLLGISPT
                     GTGKTLAYLWPSLLRLSPKKAQQLLILAPNTELAGQLFEVTKEWAEPLGLTAQLFISG
                     SSQKRQIERLKKGPEIIIGTPGRIFELVRLKKIKMMAINTIILDEYDDLLSDSQYQFV
                     QKLSHYAPRDHQMIYMSATNKIEQASLADHTLVIDLSKQALPCIEHCYMLVDKRHRTD
                     ILRKLANIPDFRGLVFFNSLSDLGATEERLQYSGASVASLASDVNVKQRKAILEAFKE
                     QSISLLLATDIVARGIDIDQLEYVINAEVPRNKEQYTHRAGRTGRMGRSGIVITLVSH
                     PEDIKRLKKFTKVTEMYLKHQQLYQKEIRG"
     gene            complement(13160..14446)
                     /locus_tag="TV193_000682"
     CDS             complement(13160..14446)
                     /locus_tag="TV193_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1512904.1"
                     /translation="MKKLNYILIILLSLLLVGVAFTFIRSWKIGQDTQRVIKLEQTAS
                     KDSPKIKKVKYLKKGKQDWYYLSPIEKADDFYVSNLPMSLYQGKQTDKAVIMVKPKLE
                     ASHIKQVNQLVIYKTVYKPQLFGLKKTTEKAVSRYHVKEDYSPFKLEELVAGRLDRIE
                     EEVGKLYPGKEIKLSTDTMIEKNQVLSDGFAIDSGNLILFGHMSIPLASLFDVINPDF
                     LEGSDKTAYEEYLEEKKAKEAEKEGQKLVALTFDDGPDPVTTPQVLDILAKYQAKGTF
                     FMMGSKVVGHEALVKKVSAAGHDVENHSWDHPDLTTLTVDQIQTQINTTNQAIEKACG
                     KRPVYLRPPYGATNDIVRRASGLKEMLWTVDTRDWENRNTAAIMANVKQQLQPGGVVL
                     MHDIHQTSVDALPSIMEYLKAEGYKCVTLSELYGSR"
     gene            14868..16031
                     /locus_tag="TV193_000683"
     CDS             14868..16031
                     /locus_tag="TV193_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1512905.1"
                     /translation="MSQKLGKQLIRSVVTALAAIAFGIFPASETTNHITYAEVNSLTP
                     SVEWPLEQYPNYYSIEGKSNINTKDFPKLYTTTEKVYKKSGRSTKRVTVSDLQYAALD
                     GYGRSGAAYGIITKDMIAMSAGYREKWESNPEPSGWYTYHFKETGKLATEADYLHSKS
                     KIKRTSNNSYESIVLSNGKIRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNND
                     RKGGMQYIENKVLNYINHNPQVHVYYKAVPIYSGSELLPRAVVVSALSSDGKIDETVR
                     VFNTVNGFTINYQYSGISHDKGMEASSESEAEDITDESTPVAEPADEEAMETEAAAND
                     TIVYVTSNGQSKVYWYNKDHLPEKVNLNKVVEMTEQEALNRGKHHSSLEKINQ"
     gene            complement(16154..18772)
                     /gene="alaS"
                     /locus_tag="TV193_000684"
     CDS             complement(16154..18772)
                     /gene="alaS"
                     /locus_tag="TV193_000684"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEL1512906.1"
                     /translation="MKQLTSAQIRQMWLDFWKSKGHSIEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKEKLYMTYYPDDKDSYNRWIALGVEPSHLIPLEENFWEI
                     GAGPSGPDTEIFFDRGEAYDPDHIGIRLLEEDIENDRYIEIWNIVLSQFNADPTIPRS
                     EYKELPNKNIDTGAGLERLVAVMQGAKTNFETDLFMPIIKEVEKLSGHTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGIHETFLYKLVATV
                     GHIMESYYPEILEKRDFIEKIIKREEETFARTIDAGSGHLDQLLAQLKEKGQDRLDGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKAAMKEQQDRARAAAVKGGSMGMQNE
                     TLAGITEPSEFLYETETVASRLSVIIVDNERSEMVSEGQALLVFDQTPFYAEMGGQVA
                     DHGVIKNDKGDLVARVIDVQKAPNGQPLHTVEVLASLALDTVYTLAIDHKRRYAVEKN
                     HTATHLLHAALHKVIGEHATQAGSLNEEAFLRFDFTHFEAVTAQELRRIEEEVNEQIW
                     KALAITTTETDIETAKAMGAMALFGEKYGKTVRVVQIGDYSVELCGGTHLSNSSEIGL
                     FKIIKEEGIGSGTRRIIAVTGQQAFESFRKQEDILKEIAHTLKVPQIEQLPSKVVSLS
                     EQLRDLQKEMAELKEKAAAAQAGDVFKKVQEANGLRYIASEVSVSDAGVLRTFADNWK
                     QRDYSDVLVLAASIGEKVNVLVASKDKRAHAGNLIKALAPIVSGRGGGKPDMAMAGGS
                     DASKLSELLAAVPEHL"
     gene            complement(19128..20129)
                     /gene="prsA"
                     /locus_tag="TV193_000685"
     CDS             complement(19128..20129)
                     /gene="prsA"
                     /locus_tag="TV193_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEL1512907.1"
                     /translation="MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSD
                     FYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKRTEEAYNKSAEQYGASFSAALAQ
                     SGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVTTLDNEET
                     AKAVLGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDIS
                     EVVSVLDPATYQNKFYIVKVTKKAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAK
                     ALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKSSSDSSKDSQSSKSKSEK"
     gene            complement(20192..20899)
                     /locus_tag="TV193_000686"
     CDS             complement(20192..20899)
                     /locus_tag="TV193_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEL1512908.1"
                     /translation="MVKSYSKNANHNMRRSIVKEDIVHYMRTQLKQNEGFLAELEAFA
                     RQENIPIIQHEVVAYFRLLLQSLQPKRILEIGTAIGFSALLMAENAPEAEIITIDRNA
                     EMIGFAKENFAKYDSRKQITLLEGDAADLLAGLTGEFDFVFMDSAKSKYIQFLPEVLK
                     HLKIGGMVVLDDVFQGGDIAKPIKEVRRGQRTIYRGLQDLFAATLDNPGLTASLLPLS
                     DGLLMIRKNQADIRLLD"
     gene            complement(20982..21620)
                     /locus_tag="TV193_000687"
     CDS             complement(20982..21620)
                     /locus_tag="TV193_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1512909.1"
                     /translation="MKTSLIFDMDGVIVDSEYIFLSTKTQMLLDRGIDTNEAYQYQFM
                     GTTFDDMWTTMKKECQLEDSVEALIAEMNHRRQAMLERDGVKAIAGAAQLIKHLHAKG
                     YRLAVASSSPKADIIRNLTALGLLDCFEVLVSGEEVARSKPAPDIFLKAAEWLSVDPK
                     TCLVIEDSKHGSQAAKAAQMTCIGFANPDYPLQDLSACDSIVKQLKAVCELL"
     gene            complement(21670..22302)
                     /locus_tag="TV193_000688"
     CDS             complement(21670..22302)
                     /locus_tag="TV193_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1512910.1"
                     /translation="MTVNLIWDFDGTLVQSSEAIRQALGLLYQTYQLPFDEAWVMDTI
                     IQESIGQLLKRLAEAHQLDFSELLAFFTREQEARDHLIALMPTAKETLALTSQQGVKP
                     FIVTHKGRTTQAVLQRLGIADYFTEVITADCGFKRKPDPEALLFLIHHYQMDKSQTYY
                     IGDRPLDLAAARAAGISSINLLLPDSDDNHHISQLSDIVELFSGKNSSSN"
     gene            complement(22292..22849)
                     /locus_tag="TV193_000689"
     CDS             complement(22292..22849)
                     /locus_tag="TV193_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1512911.1"
                     /translation="MKEIRTIALADQAAFKRFQDILLAEKASGNTFVETKKVEDFAAF
                     VEQSRRFEVQTDHPDWSTSTNYYYFLDGQLVARIGCRWQLEKGDLATIGGHIGYVTRT
                     DYRGRGIMTDLLAFALQQYQERGIKRVLITANKDNIASRKTIEKAGGILEDIVQVADD
                     YPTTSLAGQAIARYWIDLRGKDCDS"
     gene            complement(23048..24850)
                     /gene="pepF"
                     /locus_tag="TV193_000690"
     CDS             complement(23048..24850)
                     /gene="pepF"
                     /locus_tag="TV193_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1512912.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLLAAIEAARQQA
                     GHLLDSSSSLLDITELHLELARRVEKVYVYASMKNDQDTTVAKYQEYQAKASGIYAKF
                     SEAFSFYEPEFMALSQEAYQAFLAETPELTVYDHFFDKLFKTREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYASARQAAMSANFIPEAVYDTLLENVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYS
                     ERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSEYLNNLYADLNEKYYGLKKEDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFRVFEERLTELEDLVARGAHL"
     gene            complement(24840..>25284)
                     /locus_tag="TV193_000691"
     CDS             complement(24840..>25284)
                     /locus_tag="TV193_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1512913.1"
                     /translation="MIHEDLFGKVSYLVKTCSLDDDLLAFLRLPYQRKGLSAYQLQMD
                     KHLLRRIQKALLAKDSKWLKKQEEAYLAGDNLLDRPLEAYYPQVKPIACSAGFCQIHE
                     DLSHYYDCFEKYYAKAANKEVQKLFSPAYYVKMISNRNLGGPYDR"
BASE COUNT         7317 a         5880 c         4839 g         7248 t
ORIGIN      
        1 atagacaggg ggttcttaaa aatcaaaagc ccctaaaacc actctcatac caagcagtct
       61 taggagctct aagcattcat gtcaggtgat aatcattagg ctatgaaagc cttcagttct
      121 taatcctcaa taagctgaat atcagcccct aaggctgtta gcttatcaat aatgttagca
      181 tagccacgta aaataaactc aatattgcta atctcggttt taccctgagc cattagacct
      241 gcaatcacca aagcagcacc agcccgcaaa tcagttgcct taacctgtgc cccactgagg
      301 cgattagagc catgataaac aatttggctg ccaagaatgg caatatctgc tcccatacga
      361 gcaagctctg gcacatggtt gacacgcttt tcatatatcg tatcaatgat actaccacga
      421 ccctcagtcc ttaaaagcag aggagtcaaa ggctgctgta ggtcagtggc aaagcctgga
      481 tagggagagg ttttaatagt gactgctttc aaggcttcct gcttttccac aaaaatagaa
      541 tcctcttcaa ccgtcattct cacacccatt tcctctagct tagcaataaa gctctctaag
      601 tgctcgtaaa ggacattggt aatccttacc ccactaccaa cagcggctgc caaggcaata
      661 taggtaccag cctcaatgcg atctgggatc acctgatgtc tggtgccatg aagcctttca
      721 actccctcaa tcgtaatcac atcagtacct gcaccacgaa tatgcgcccc catgttattt
      781 aacagtgtcg caacgtcaat aatctcaggc tctctagctg cattttcaat aatggtctta
      841 ccctttgcct ttgtcgcagc aatcatagta ttaatggtag cgcctacact gatagtatcc
      901 atgtagatat gagcgccatg aagctgctga gcctctgtca tcaggtgcat gcttgctccc
      961 tcataagata tctgggcccc cattgcttca aaagccttca gatgaagatc aataggccta
     1021 gggcctaagt cacagccacc cggcaagccc acaaccgcct gcccaaagcg tcccaataga
     1081 ctgccataaa aatagtaaga ggctcttagg ctgttaattt taccataagg cataggaata
     1141 tcttgaaccc ctctggggtc aatctccaag gtatccccct gataggtcac catagctccc
     1201 atgagcttca tgatttcaat aagactgtca acatcactaa tagctggtac cccatctaaa
     1261 gtgacaacat cgtctgccaa aataatcgca ggaatgagag ctacaacgct atttttagcg
     1321 cctgaaactg ccacctctcc ggataaggct tttccaccat taataataat ttttcgcata
     1381 ctttcaaaac tttctgatac tagaattcaa cctttttatt ttatcacaaa tagcggtcta
     1441 ttacaatcac ctcatcacca gctgctgcaa caggcttaac aacctgcctc ttgatcactt
     1501 ttcataacag gtttttgaga agccagactc ttatctggat ctttcttctg ctgcgcaggc
     1561 ctttttgtct ttcatagccg ccaagcctga caagttttgc tggactaaaa aagctcccaa
     1621 ccagcagcac agccgctagc tcaggagcta ttataccttt aagtcaatca tcaactaacc
     1681 ggcgctcaat ctgcttaagc accctctgac agtgctgcca ccgcttctgt caatggagat
     1741 accttgtcca attgttccca aggcaggtca atgtctgttc gccccatgtg cccataggct
     1801 gctgtctgcc tatagattgg acgcttgaga tcaagcatct taatgatccc tgctgggcgc
     1861 aggtcaaaga cctgacgaac agccgcttcc aaaatacttt ctgacactgt tgatgtccca
     1921 aaggtatcca cacgaactga aactggctgt gcaaccccga tagcataggc taattgaacc
     1981 tctgctttac ttgcaagccc tgctgccaca aggtttttgg caatataacg agctgcataa
     2041 gaggctgagc ggtcaacctt agttgcgtct ttaccagaga aggcaccacc accatgacgc
     2101 gcatagccac cataggtgtc aacaatgatc ttacgaccag tcaagccaga atctccctga
     2161 ggaccaccaa taacaaaacg cccagtcgga ttgataagga atcttgtctt ctcatctaga
     2221 taatgggctg gaataacagc cttaatcacc tgctcaatca tatcttgacg aatctggtca
     2281 ttgcttactt ctggatcatg ctgggttgat ataacaactg tatcaacacg aacaggctta
     2341 tcatgttcat catattcgac cgtaacctgt gatttagcgt ctggacgcaa atagctgatc
     2401 tcacctgatt ttcgcagtgt cgccaaacgg cgtacaagct ggtgagataa ggaaatcggc
     2461 agtggcatta gttctggtgt ctcatcaatt gcaaagccaa acattagccc ctgatcccca
     2521 gcaccaatcg cattgaaatc atcgctttgt ccttcacgtg cttcaagtgc ttcattaacg
     2581 ccttgagcaa tatctggtga ctgctcaacc agagatggat gaacacccac tgattctgct
     2641 gaaaagccat attctgcctc agtatagcca atctcagcga tggtatcacg aaccacacga
     2701 ttaatatcca cataggcagt tgttgaaatt tctccaaaaa cgtggaccga gcctgtgtaa
     2761 acgcaggtct ctgcagcaac gtgtgcctct ggatccttgg ctaaaatagc atctaaaata
     2821 gcatctgaaa tttggtctgc aatcttatct ggatgccctt cagatactga ttcagacgtg
     2881 aaaagtttac gttctgacat aaaaatgtcc ccccttaaaa agaatgatac ccaccagcac
     2941 acatgccaga taggattttc ctagcctcac tcatcaagcc agccgccaat acaaaaggac
     3001 tgtatccaag ctagcctatg actaacgctt agcgagttac aaagtaccgg cttttagact
     3061 gctatcctca gataacaaag ccgtcttatc gggacttaat aacttatcta ttataccact
     3121 tttagcggga tttgtaagag ctccatcagc ttttttctca aaataagaaa aggaataccg
     3181 ctacaggcgt attcctcctc ttaatgtcgt gataatcagc gcaagctatc gattaaccat
     3241 ggtggtgctc atcgtgatca tgatgctcat ggtcatgctt atctgctgcc tcttgatcag
     3301 tatcagccgg cttatgctcg tcttcaacag cttctgctgg tgtggcatta tttagactac
     3361 caccctctgc tgccttgaag ttcttgataa ttccttgtgg gaattgtccg ctttcagcag
     3421 ctagctcctc agctgggaag tggttaccat cagcctgaat gtatttcagg gtttggttag
     3481 gctccttcaa ggccaaggtg ttaatcttgt tacgattaac attaattgct tctagggcga
     3541 gataattgtt gacaccctca aaattagtca gctggttctc ttcaaggtta agagactgta
     3601 atgagctttg tgtacctggt aaggccaagc tattaatcat gttctggtta gctgatagct
     3661 gaatcaggct cttattgtgc tcaagacctg tcaagctgtt aagcttgttt tggtcaacca
     3721 ctagctgctc taatgccggt agatccttga caaagctaag gctttgtaaa ttaacctcct
     3781 tggcagtgat ttccttgaga gcagaggatt ttaaggttga caaatcaagg tcagggttgt
     3841 ttgacacaaa gagtttggtc aattgtccct tgtttgacaa ggcactcaag tccttaatct
     3901 gattgtgctc taggctgaca gcgactagct tttgagcatt tgccaaggca gaaagatctg
     3961 taatcttgtt aaagtcaagg ttaacggact ctaggtttgg caattctttc aaaatagaaa
     4021 tatctgtgat atcatttcct gctgccgaaa ttaccttgta atgcggaaag gctttaagga
     4081 agctcaaatc agaaacacca ttttgagaaa tatcaattcc ttcaagcgtt ggcaggttct
     4141 tcaagaaatc ataattttta atgccggtct gtgtcatcca caattgtttg aggttcttga
     4201 actggtagac tggggtaata tcagtgattg gggtaaagcc aatacctaaa atctgtatat
     4261 taggcatcag gtttaaacct gcccgcttaa gaggatcctt aatctcaccg atattgaggt
     4321 attcaacagt cgccaaccat gccttcattt tctctaggtc tcgctctctt gatggaaact
     4381 cagttggtgc atttgcatgg ataatggacg aaatcacttc ctcatcaaag ccaagctttc
     4441 tcagagttgc cataccgatt ctatccttag catgcggatc tactgcatga ggatcaaaag
     4501 gttttgataa atcaatatcg tcaatatagg ttgcatgacg atggtcacca tgtggatagt
     4561 caagaatgat accttcttct gtatgctcca cacgaatgct gtcctcagga atatttaatg
     4621 acttagccaa atatgctttt ttcaaagcaa tcgttttctc aagatcactt tgtggcttag
     4681 ctggtgcttc ttcctttggc tgttcgatta aatgcttcca cttgctgtta cgcaagcttt
     4741 cataagtgac taaatgattg tggccattgt gatcaacaat caatccatat gatgttcgac
     4801 cgacaatacc tgtcccgtca aacaagaagc catcacttgt tgggtaatca acacctgcaa
     4861 attttccaga cggtgatgat ggagctgata gtggcacatg gttaggcact ggataagcta
     4921 cctgaccacc tagtgagctt tttaggatat agtggtaatg atcaccatga cggacaatat
     4981 agcccaaggc gtcctcagct acaatatcag ctgggttaaa cacatagtga tggtgcgggt
     5041 cattagcact agtatggtga tgacctgatg ctgccttggt ctgctcaggc ttgtttaggt
     5101 cagcgtcctt tggaatcagg tactcaaact tgctgccctt gagatctgca taaaaaataa
     5161 aatgcgaatg cccattatgc tcaacaacaa taccgttttc tgttctagat aagatttttg
     5221 aatccttggt caagataaaa ccgtcatcag ttggaaagtc aatccccgct actcccttac
     5281 ggtcttttct tgtttgctta acctttttag actgtttctt tttggtcgct tttttagctg
     5341 tctgttttgt cttaggctga tttgttggct gctttgtcga ctgacaagct gtcagggtca
     5401 ggtgacaagc cataaacagg ctagccatta gcattaattt tttacttttc atctttcctc
     5461 cataaattaa ctggttaaat aagatattaa ctagttaaat ataccaaaaa aacaaataat
     5521 ttcaactgtt ttcttatttt taattcattc tcattcaaca atcatagtag cttggctagg
     5581 ttggcagaaa aatgagcctc tcctactctc atcaaataaa cagatagcct taatgatggc
     5641 tgagataaca gcatacaaag tcgttaaagt cacttgtaag aaaaagaagg acatatctta
     5701 ccaccactat cttgctcatc aaagccctac ggctttcaga caaaatcttc ataacagcgg
     5761 aaaggctgat gaagcagctc agacaaaaag agcaagctcc ttaacgtcaa ggatcagaga
     5821 tcagcacaaa aataacagca ggctacatta agaactgcaa ttccttgaaa tagaattgct
     5881 tttttacaaa aaaatcgtct ccctagactg ttccatcatc tcacgtcatt tgtattattt
     5941 gctcttgaaa tccagtcatt ttatactata ctagaattat gaagacatct gaaaaaattt
     6001 accaattact agcttgcagc gacgactatg tcagtggaga atacttggca gagcagctca
     6061 agctttctag aacctctgtc tggaaatcca tcaaaagcct tgaaagtcaa ggccttcaca
     6121 ttgaatccct caagcataag ggctatcgcc ttattcaagg agatatattg ctgccagagc
     6181 tcatcagcca agagctcaac atgcctttat cttatcatga gaaaagccag tcaacacagc
     6241 tagacgccaa gcaaggaatc gagctaaagc atactgctcc taggctctat ctcgctccaa
     6301 gtcagtatgc ggccaagggg cggcttaatc gccaattctt tgcgtcacct catggcggca
     6361 tttacatgtc cttgcatctc aagccaaatg ttccttacgc agacatgcct ccttacacca
     6421 tgatggtggc ctctagtatt gttaaggcta tttcaagatt gaccggtatt gacacccaaa
     6481 tcaaatgggt caatgatatt taccttggcc ataaaaaaat cgccggtatc ctgactgagg
     6541 ccattacctc tgtggaaaca ggcgtcatta ctgatgtgat tattggcgta gggcttaact
     6601 tttttgtaac cgaattttct gaaaacctca aagaacgagc aggctctctt tttagcaaca
     6661 agcctagtat tactcgaaat gccctaatca ttgacatttg gaagctcttt accacaatac
     6721 caatcaagga ccatattaag gtctacaaag aaaaatcact tgtccttcaa aaacaagtga
     6781 gcttccaaga aaatgatcgt caaaaaacag caactgccat tgacctgact gatgaaggac
     6841 acctcatcgt tcaattagac aatggtcagc tacaggtctt aaggagcggc gaaattagtc
     6901 tttcttcctg gggggattaa cagcattaat gatgtttttg gtaaattggt caatagcata
     6961 agcacgcctt aaatctctaa agagcaaaag accccaaaac agagcaaaaa tataatcgcc
     7021 tgaaaataat aaatcgctga aaaaataagc ttcaaaggca caaatgaatg ccataaacat
     7081 aaattgtcga atagtcatac tactattata ccaagaaaac taaatttcca ctaacgattt
     7141 tcacgcagct tgaagaaaaa ggcagttagc ctgcttcaag cttttttgct gctctttgat
     7201 agcctgtaac agtcaaataa aaaagagctc actctaaaaa cgacgccaaa agccagcttg
     7261 attgctaggc ttgtagtcaa ttgtctcaaa tcagtgaatc actaagcctt ataagaactc
     7321 agtcattggg tcacaatgac acctagctct aagcagcaaa aaagagaacc acaccggtcc
     7381 tctctagctt ggcttgtcag ctatctatta gtgctgacaa tgagccctgt catctcctta
     7441 ttctagacaa ttgatacact accaatcatc agctagcgct aatcctctat gagatgaatc
     7501 ttatcagtta aaaagtcaaa cccctcaggc atgtcaaagg tcgcttgctc agactctttg
     7561 gctgtctctt ttttggtttt gatggtcatg gcaaactccg agcgaatatg gtggaagtct
     7621 gcctttggta ctgccaagat atgaggagaa aaccctgctg ccttactcat gatattccca
     7681 aacatatcat tcaaatcctg acgcttcatg gcctgctcag cgttaaaggc ggcctcaaag
     7741 gccaaaatag cattttcact attggctaaa acaggctccg agcctagtaa caaagctcga
     7801 tcctgtgcag aaatactatc taaaatctca ttccaagcac tttttagcgc ttctaaatat
     7861 tgtcgtgact gctggctatc ttgaacagtt tcctccatga ttttcaatat cttttcccga
     7921 tcaaccttgt aggtaaaggc ctttggcttg atggaatgag ctggtgtagc ctgcgcagtt
     7981 agaccctttt gagcctgtag ctgtgatatc gtctccctca gctgactaat ctcatgcttc
     8041 aagtcatcaa catcagctag caggctagac ggtatcgcag tgtctgctgc ttgtccttgc
     8101 tctgccagct gaatggtcat catttcagcg tagattctag gatgggttcc ttttttgatc
     8161 tcaggcaaat gcttggttac tgtagcaatc attgtaaaaa gctgatcaaa agacactgca
     8221 aggttatcat caaaaagagc tgactgcctg tgatgatcac cacctgattt cacaatgagc
     8281 aggtctctaa aataggttag cagatccgtt gcaaagcgac tcatgctctt gccactatca
     8341 taaattgttt ctagattagc taaggcctga cttgtttttt gcctgatgag atgctgaacg
     8401 tagtcgtcta aggccgaaat agaaatagag cctgtgattt cttctgcaat agcaagcgtc
     8461 actcgattgt caaaggatag gctcaaggcc tgatctaaaa tggatagggc atcacgcatg
     8521 ccaccttctg ctcgtcttgc aattaaatga agcgcctcta tttcataggc tatgccctcc
     8581 ttgtccagta tcgccgccaa atgctcacaa atagctggct gcttaatggc tttaaattca
     8641 aatcgctgga ctctagacaa aatagtagct ggaatcttgt gtagttctgt tgtggctagg
     8701 ataaaaacca cattgtcact cggctcttca agggtcttta ggagcgcatt gaaggcccct
     8761 gttgatagca tatgcacctc atcaataata taaaccttgt aggttgcccg gctaggagca
     8821 taggttgact tatctcgaat atcgcgaatt tcatcaacac cattattaga ggcagcatca
     8881 atttcaatca cgtcctccag gctgccagtt gtaatatctc ggcaaatatc acaatgattg
     8941 cagggctctc ccttgacctg attagggcag ttcattgcct tagcaaaaat tttggctgcg
     9001 ctggttttac cagttcctct tggacctgaa aagaggtaag catggcttat cttttctgac
     9061 tcaacagcct gctttaaggt ggtcgaaata actgactgcc caaccatttc agcaaaggtc
     9121 tggctacgat acttccggta aagggcttga tacattaatt ctcaactcca aacatgtcaa
     9181 aacgaaaaga tgtattttct agtaataagg ctacaaattg ctctaaatag tcttgatcta
     9241 tctgatcata atcagcaaca agactggaat ccaaatccag aacaccaaca agcctgccag
     9301 ccttaagcat tggcacaaca atctcgctca tggctgctga atcacaggaa atgtaattag
     9361 catgcttttt gacatcatca acgatgatgg tttgaccaga ttgagctgat tctccacata
     9421 ctcccttgcc aagcttgata tgcacacagg aaacctttcc ctgaaaggga ccaaggatca
     9481 attcttgacc atcaaaaagg taaaagcctg caaaaacaga atgaggcagg gtcattttta
     9541 agagggcact agcattagag agattggcca aggcattgct ttcattagaa aataaggctt
     9601 tagcttgagc caataatagc tgataatgtt caatttttgt cgtcttattc atggttctta
     9661 ttataacata tctgctacta atcgttaaac gatttccaca ggaaaagaat tttaatcagc
     9721 ctctctagaa aagaaagaga ttttatgata aaatagtgag taatattaaa aaaataggag
     9781 agtcagatgc cgttgttgag atataaaaag attatcgcta cgaccttatt tatgttatta
     9841 gtgtttaatg gtattgagta tgaatgtcta aaccttgtca gtcccaaaca aaccttttac
     9901 caatccgctg ccttaatcct ctcaaccagc ctactaggga tctatctgat tcccttttca
     9961 ctggctattg cttatctcaa gcgcatctac cagataagga tctcaaccct gctattagct
    10021 gggctaggcg gtctttatat tagtggcttt ttagcctcct ttggcaatca ggttttagag
    10081 caattttgga ttagcctgat aaagcccaat attgccttag aggagtggac gggagctttg
    10141 acagggcctt ttgtggaaga gcctattaag gcctttgcag ctatgcttgt catttatttg
    10201 ctgccagcta ttaatcttaa gcaaaaatta gtcatcagtc tcatttctgg catgggattc
    10261 cagctgactg aggacattag ctatattgca agtgcggctg atcggtccat aaatgacatt
    10321 ttgcctacaa cgcttgccag gattagcagc tcaccaaact ctcattgggt ctatactggt
    10381 atttttacaa tgggagcata ccttttaatt aaaaaatctc aattattccc aaggtctctg
    10441 cagattttct gggtggtaag tcctctagcc ctacatttta tatggaactc tcctatctca
    10501 gatttagctg gtgtcgcagt tattcatgga acaataacaa cccttatctt tatcagtcta
    10561 ttcaaaaaaa tccatgccct agacgacagc atcgcctact agcgtcatag gacacgagca
    10621 accaagccca gccgcatttg ggcatgtgat ggctcatatg catatatagc tactcacctc
    10681 tcgcttaagc tataggcagc taaataccta tcacaatagc agaaaaaatg actaccagtc
    10741 ttaaaagggc tagtagtcat tttaagctaa aaacaagcac ttcttacagg atataccact
    10801 gatacagata atagcaaagc acaagggtca tcagtatccc catataccat gaaaggacaa
    10861 aataccattt cttcgtttta tggttaaaat aatgcccagc tagataggct ccaatcccac
    10921 cacataagag tgacaacgtt aatagcattt tctcagaaag tcgccattga cctttttggg
    10981 ctctgtgttt atcactgcca taggccgcaa agaccacagc attccaacca aaaagcaaga
    11041 ttaggcttgg tagcatttgt ctgtctccaa tcacagcact acagctcacc taagatgctg
    11101 gcaatctttg tgttgatgag atcaatagca accacattgc taaccccttc tggaatgaca
    11161 atatcagcat agcgcttact tggctcaata aattgatgat acatcggctt gacaacgctt
    11221 gtgtactgct caataatgct ctcaaggctt ctgccacgct caaccatatc acgctgaata
    11281 cgacggataa tccgaatgtc atcatctgta tcaacaaaaa gcttgatatc catcagctca
    11341 cgcaaacgct cgtcctctaa taccagaatc ccctcaacaa taatgacgtc ctgaggctct
    11401 tggcgaaaag ttctgttgct gcgagtatgc tccttataat catagattgg aatatcaaca
    11461 ggccggccag ccaagagttc ctttagctgc tgaatcatga aatccgtatc aaaggctaac
    11521 gggtgatcat aattagtctt aaccctttcc tcaaagctga tatgtgattg atccttgtaa
    11581 tacgaatcat gctgaatcat cgcaattctc gcatttggaa agctatttaa aatggcacga
    11641 gacacgctag tcttaccacc accagaacca ccagtcacac caataataat gggtttttta
    11701 agcattgtaa actccaaatc taaaagtctt tcggtctatt ttaccaaatt tgccactata
    11761 atgctataat gaagagaaaa caaaataaaa ggatagatat atgataacca accttcccac
    11821 tcaatggcag gaaaagctgg caaagcttgg ctttactaat ctcaccccaa tccaagagca
    11881 ggtctttcag cccattgttg atggcaaaag cctattaggc attagcccca ccggaacagg
    11941 caaaactctg gcctatttat ggccaagcct tctcaggcta agccctaaaa aagcccagca
    12001 gttgctgatt ttagcaccta atactgagct agctggacag ctttttgagg ttaccaagga
    12061 atgggcagag cccttaggat taactgcgca gctctttatt tccggaagca gccaaaaacg
    12121 ccagatcgaa cgcctcaaaa aaggcccaga aatcattatc ggaacaccgg gacgcatttt
    12181 tgaattagta aggcttaaaa aaatcaaaat gatggccatc aataccatca ttttagatga
    12241 atacgacgac ctactgagtg actcccaata ccagtttgtc caaaaactct cccattacgc
    12301 gcctcgtgac catcaaatga tctacatgag tgctactaac aagatagagc aagccagtct
    12361 agcggatcat accttggtca ttgatctgtc taagcaagca ttgccttgca ttgagcactg
    12421 ctacatgctg gttgacaaaa ggcatcggac cgatatccta cgtaagctag caaatattcc
    12481 tgactttcgt ggtctggtct tttttaacag cctgtcagac ctaggtgcta ctgaagaacg
    12541 cctgcaatat agtggagctt ctgttgcttc tctagccagt gatgtgaatg tcaagcagcg
    12601 aaaggccatt ttagaagcct ttaaagagca gagcatttca ctgctgcttg cgacggacat
    12661 agtcgctcgt gggattgata ttgaccagct agaatacgtc attaacgctg aggttccccg
    12721 taataaagag caatatactc atagagctgg gcgaaccggt cgtatgggac gatcagggat
    12781 tgtcataact cttgtcagtc accctgaaga catcaagcgc cttaaaaaat ttaccaaggt
    12841 cactgagatg tacttgaagc atcagcaatt ataccaaaaa gaaataagag gctagctcaa
    12901 aggatataaa cctaaaaagc ttgcctccaa gtatgatgta aagcaactaa tcactatttc
    12961 ttacccttgc tactaaaaaa acgaacgtaa agtccttctg acatgaagtc aaaaccttac
    13021 gttcgtttta tattatactg acaccactgg ctttattagt atagtagata ctggccatgc
    13081 ttagccagac tagatacttt cttgaagtga gcccgccatt tagtcatgct ctagagcctt
    13141 acttgctttt tctgactgac tagcggctac catatagctc agataaggtc acacatttgt
    13201 atccttccgc ttttaggtat tccataatac ttggcaaggc atctacactg gtctggtgaa
    13261 tatcgtgcat tagaacaacc cctccaggct gcaattgctg cttgacattt gccatgatag
    13321 cagcagtatt acgattttcc caatctctgg tatcaactgt ccaaagcatt tccttaagac
    13381 ccgatgccct tctaacaata tcattagtag ctccataagg aggacgaaga tagactgggc
    13441 gttttccaca ggccttttcg atggcttgat tggtcgtatt gatctgtgtt tggatctgat
    13501 caacggttag ggtcgtcaaa tcagggtgat cccaagaatg attctcaaca tcatgaccag
    13561 cagcactaac cttcttaacc aaagcctcat ggccaacaac cttagacccc atcataaaaa
    13621 aggtcccctt ggcctgatat ttggccaaaa tatctaaaac ctgcggtgtg gtcacagggt
    13681 ctggaccatc atcaaaggtc agagcgacta gcttttgtcc ctctttttct gcctcttttg
    13741 ccttcttttc ctccaaatac tcttcataag cagtcttgtc tgaaccctct agaaaatctg
    13801 gattaatcac atcaaacagg cttgcaagag gtattgacat atgaccaaat aaaataagat
    13861 tacccgaatc aatggcaaag ccatcgctta atacctgatt tttttctatc atcgtatcag
    13921 tgctcagctt gatctctttg cctggataaa gcttgccaac ctcttcctcg atgcgatcta
    13981 agcgaccagc aactagctcc tctagcttaa aggggctata atcctctttc acatggtaac
    14041 gactaacagc cttttctgta gtctttttta gaccaaataa ctgaggcttg tagaccgtct
    14101 tgtagataac caattgattg acctgcttga tatgtgaagc ctcaagctta ggctttacca
    14161 tgataacagc cttgtcagtc tgcttgcctt gatacagaga cataggcaga tttgacacat
    14221 aaaaatcgtc agccttctca atcggagaca ggtaatacca atcctgcttt cctttcttga
    14281 gatacttgac ctttttgatc tttggactat ccttagaagc agtctgttcg agcttaatga
    14341 ctctctgagt atcctgccct attttccaag atctaatgaa ggtaaacgca acaccgacca
    14401 acaataaact taataaaata atgagaatat aatttagctt tttcaatctc gtcctccaat
    14461 taccctacaa ttttaacaca agatagttgg aaaataaata aaaaaagtta ggtttcctta
    14521 acttttttca gtccaaaata agggcaaaaa agtgttttat ggtgcaggat ttgcctgagt
    14581 tattttccct ttatcacagc catttgtcac tggataaggg gctagatatt atacctaaag
    14641 cttctcttta ttgctatcat tattctgaca ttcttaggca tgctatttcc cttgatagga
    14701 cttgattgct gtttctttag cttgtaagga tctcctaaaa atgagagtat ttttaagcct
    14761 ataatttata tattcgaaaa attttgacaa aaatgaggaa aaatattgat ttatttagct
    14821 ttagtgataa aatgagggtg aaaaattaaa taaaggagga cattgatatg tctcagaagt
    14881 tgggaaaaca acttattcgc tctgttgtta ctgccttagc cgccatagca tttggaatat
    14941 ttcctgcaag cgagacgact aatcatatca cctatgcaga ggttaactcc ttaacccctt
    15001 cggtagaatg gcctttagag cagtatccta attactatag catagaagga aagtctaata
    15061 tcaacaccaa ggattttcct aagctataca ccactaccga aaaggtttac aaaaaaagtg
    15121 gtcgaagcac taagcgcgtt actgtttctg atctgcaata cgctgcactt gatggctatg
    15181 gccgttcagg agctgcctat ggtattatca caaaggatat gatcgcgatg tcagccggat
    15241 accgcgaaaa atgggaaagc aatcctgagc caagcggctg gtatacatat catttcaaag
    15301 aaactggcaa gctagctact gaggccgact accttcacag caaaagcaag atcaaacgaa
    15361 cctcaaacaa tagctatgaa agcatcgtcc ttagcaacgg taagattcgc aacggctatc
    15421 tttttgatcg tagtcattta attgctgaca gcttaggtgg tcgtcctttt agaaataatc
    15481 tcatcacagg tacacgtact caaaacgttg gcaacaacga ccgcaagggg ggtatgcagt
    15541 acattgaaaa caaagtccta aactatatta accacaaccc tcaggttcac gtttattaca
    15601 aagccgtacc aatctactca ggctctgaat tactccctag ggccgttgtg gtttcagcgc
    15661 tctcctctga tggtaaaatt gatgaaaccg taagagtctt taacactgtc aatggcttta
    15721 ccatcaatta ccaatatagc ggcatcagcc atgataaggg catggaggct tctagtgagt
    15781 cagaagctga ggatattaca gacgaaagca ctccagtagc tgaaccagct gatgaggagg
    15841 ctatggagac agaggctgct gctaacgaca caatagtcta tgttacaagt aatggccaat
    15901 caaaggtata ctggtataat aaggaccatc tgccagagaa ggtcaatctc aataaggttg
    15961 tagaaatgac cgagcaggaa gccctaaatc gaggaaagca ccattcctcc ttagaaaaaa
    16021 taaatcaata gtctcataac gactaacaca agagctggtt gaagcaacca gctttttttg
    16081 tgtgatgaag gattagacag ctccttagct aaaagataaa gaggctgata aagcactcaa
    16141 cctcttatcg cttttataaa tgctctggta ctgcggctaa tagctctgat agcttgcttg
    16201 catcactacc acctgccatc gccatatctg gcttaccgcc accacgaccc gacacgattg
    16261 gcgctaaggc cttaatcaga ttgccagcgt gagctctttt atccttactt gcaacaagaa
    16321 cattgacctt ctcaccaatg cttgcagcca gcacaaggac atctgaataa tctctttgct
    16381 tccaattatc agcaaaggta cgcaagactc ctgcatctga tacggatacc tcactagcaa
    16441 tgtaacgtag accgtttgct tcctggacct ttttaaagac atcaccagcc tgagctgctg
    16501 ctgctttttc ttttagctct gccatttctt tttgcaaatc gcggagctgc tcgctgaggc
    16561 tcacaacctt acttggaagc tgttctattt gcggcacctt aagcgtatgt gcaatttctt
    16621 ttaggatgtc ttcttgcttg cggaagcttt caaaggcctg ctgacctgtc actgctatga
    16681 tacgacgtgt tcctgagccg atcccctctt ccttgataat cttgaaaaga ccaatttctg
    16741 atgagttgga caagtgagtc cctccacaaa gctcaacaga ataatcgcca atctgaacaa
    16801 cacgaacagt tttgccatat ttttcaccaa agagggccat agctcccata gcctttgctg
    16861 tttcaatatc agtttctgtg gttgtaatag ctaatgcctt ccagatttgc tcattgacct
    16921 cttcttcaat acgacgcagc tcctgggctg taacggcttc aaagtgtgta aagtcaaagc
    16981 gtaaaaaggc ttcttcattt aaggaacctg cctgagtggc atgttctcca ataaccttgt
    17041 gaagggcagc atgaagcaga tgagtagcgg tatggttttt ctcaacagca tagcggcgct
    17101 tgtgatcaat agcaagagta taaacagtgt ctaatgcaag gcttgcaaga acctcaacag
    17161 tgtgaagagg ctgaccattc ggtgcttttt gcacatctat cacacgagca acaaggtcac
    17221 ccttatcatt tttgataacc ccatgatcgg caacctgacc acccatttca gcataaaacg
    17281 gtgtctgatc aaacacaagc aaggcctgtc cttctgaaac catctcacta cgctcattat
    17341 caacgatgat aactgataag cgagaggcaa cagtctctgt ttcgtacaaa aattctgatg
    17401 gctctgtgat gcctgccagt gtctcatttt gcatgcccat tgagccaccc ttaacagctg
    17461 ctgcacgggc acgatcctgc tgctccttca tagctgcctt gaagccttca tgatcaatct
    17521 tatagccagc atcttctgct aattcttcgg tcaattcaac tggaaagcca taggtatcat
    17581 acagcttaaa gatatccttg ccatcaagcc tgtcttgccc cttttccttt agctgcgcca
    17641 gcaattgatc caaatgccct gatcctgcat caatggtacg tgcaaaggtt tcctcctcac
    17701 gcttgataat tttttcaata aagtcacgct tctcaagaat ctctggataa taggactcca
    17761 tgatatgacc tacagtagct actagcttat aaaggaaggt ctcatgaata ccgagcctac
    17821 gaccatgcat aacagcacga cgaagcaagc gacgaagcac atagccacga ccttcattac
    17881 caggtagggc accatctcca atcgcaaatg acaaggcacg aatgtggtct gcaatgacct
    17941 taaagctcat gttgtcacca tcttggtcgt aagtatggcc agatagcttt tccacttcct
    18001 tgatgatcgg cataaatagg tcggtttcaa agtttgtttt tgcgccctgc ataacagcca
    18061 caagacgctc taagccagca cccgtatcaa tgtttttgtt tggaagctcc ttgtactctg
    18121 agcgaggaat tgtagggtct gcgttaaatt gagacaaaac aatattccaa atttcaatat
    18181 aacggtcgtt ttcaatgtcc tcttccagca atctaatccc aatatgatca ggatcataag
    18241 cctcaccacg atcaaagaaa atctctgtat caggtcctga cgggcctgca ccaatctccc
    18301 aaaaattttc ctctaatgga atcaaatggc ttggctcaac gcccagagca atccaacgat
    18361 tgtaagagtc cttgtcatct gggtagtagg tcatgtataa tttttccttt ggaaaatcga
    18421 accattccgg acttgttaac aattcaaagc cccactcaat cgcttcgtcg cgaaaataat
    18481 ctccgataga aaaattacca agcatttcaa acatagtatg gtgacgagct gtcttaccaa
    18541 cattttcaat atcgttagtg cggattgact tttgagcgtt ggtaatacga ggattttcag
    18601 gaatgactga cccatcaaaa tattttttga gggtggccac accagagtta atccaaagca
    18661 gggttgggtc attgactggc acaagattgg ccgaaggctc aatagagtga ccttttgatt
    18721 tccaaaaatc aagccacatt tggcggattt gggctgatgt taactgtttc atgattaaga
    18781 taccaagagc gattagagag actgggtatg attgtcctta gcataagtag cctggggaga
    18841 cgatctctac tcgcattcag ttcctttcgt tgatttttta tgggattagg ctaaaagcca
    18901 tcaaaacaaa acaagcccat atcacagagg gcgaaaaccg cggtaccacc tctattcaat
    18961 gagcttgtca ttcttaatta cttatatcag ataaaatcac attaagcagc atgcctatca
    19021 gattatccgt aactcacagc aaccgtcact tctctgggtc aaatccttga taaacaattc
    19081 ttaactaaac cagtataaag cttttttgag cattcgtcaa tgaaaatcta tttttctgac
    19141 ttagatttag aagattgact atccttgctt gagtctgaag atgatttctg atctgacttg
    19201 cttgtgttcg ccttgcttgc ttttttatca gtattggcat actgtgccaa gatattagca
    19261 aatgcttggt ctttgatctt aacatttgcc ttgtctaagg cctttgcaat gaccttattt
    19321 tggaaatcaa tgttttgtgt cttttcagcc aagacaattt cttttagacg tttcttatat
    19381 ttcttccaat cagaagcctt ttcggctttt ttggttacct taacaatata gaacttgttt
    19441 tgataagtag ccggatctaa gacagaaacc acctctgaaa tatcaccctc ttttaatcct
    19501 gaggcggcct tgatcacatc tgctggtaac ttagtgtctc ctgagtcaaa cttatagtct
    19561 accttcttgt ctgctgctgt tgtcttttcc ttagcaatag cagcaaagtc agcaccctca
    19621 gccttaacct cacctaaaac agcctttgct gtttcttcat tgtctagagt agtgacctga
    19681 gtagtcattt ctggtgtgta tgactcatag gcttttttgt aatcagcatc tgtcagctct
    19741 tttttagctg cttctttaac agcatattca accagcatgg ctgagcgaat ttgacgcttg
    19801 taggtatctg ttgtcaagcc agactgcgca agggctgcag agaatgacgc accgtattgc
    19861 tcagctgatt tattgtaagc ttcttccgtt cttttcttag aaaccttttt accgtattgg
    19921 tcctcaaaaa cacgactaac cacaaggttt agcattgctc tttgagaaat ctctgtattt
    19981 tttgtttcat tgtaaaaatc actaacactg atagtgtcgc ccttcatcgt aatgacactt
    20041 gtattgtcat ttgtagactg acaggctgct agggtcattg ctgatgctag ggttacgata
    20101 ccagcaagta atttagttga ttttttcatg tgattttgtg ctcctttttg tcattaacca
    20161 gtatattata tcacaatttc ttaaacgtaa cttaatctaa caaacgaata tctgcttgat
    20221 ttttacgaat catcagcaag ccatcactaa gcggcagcag gctggctgtc aatccaggat
    20281 tatcaagagt tgctgcaaat aagtcctgaa ggccacgata aatcgtgcgc tgtcctctcc
    20341 gaacctcctt gatcggctta gcaatgtcac ccccctgaaa cacatcatct aaaacaacca
    20401 ttccacctat ttttaagtgc tttaacacct ctggaagaaa ctgaatgtat tttgattttg
    20461 cagagtccat aaaaacaaag tcaaactcgc cagtaagtcc tgctaaaaga tcagccgcat
    20521 ctccttcaag aagggtaatt tgcttgcggc tatcgtattt tgcaaaattt tccttggcaa
    20581 agccaatcat ctcagcattg cgatcaatcg ttataatctc tgcctcagga gcattttctg
    20641 ccattagcaa ggcagaaaag ccaatagctg tgccaatttc taaaatcctt ttgggctgca
    20701 agctttgcaa taaaagcctg aaataagcaa caacctcatg ctggataatg ggaatatttt
    20761 cttgtctggc aaaggcctca agctctgcta aaaagccttc gttttgcttt agctgcgttc
    20821 gcatgtagtg aacaatgtct tctttgacaa tagagcggcg catattatga tttgcatttt
    20881 tactatatga tttaaccatg ctatccatta tataaaaaaa ctctaggtaa tgctagggct
    20941 ttcactagcc tattcacctt tgacgatctg agtagtatct atcaaaggag ctcacagaca
    21001 gccttaagct gcttgacaat gctatcacaa gcagacaagt cctgtaaggg ataatcagga
    21061 ttggcaaagc cgatacaggt catctgagca gccttagcag cctgactacc atgcttacta
    21121 tcctcaatga caaggcaggt cttgggatca acgcttaacc attcagcagc cttaagaaaa
    21181 atatctggcg ctggctttga gcgagcaacc tcttcaccac taactaacac ctcaaagcag
    21241 tccaaaagac ctagtgcagt gagatttcta ataatatctg ccttaggcga tgaggaagct
    21301 actgccaagc gatagccctt cgcatgcagg tgcttgatta attgagcagc acctgctatg
    21361 gccttgacac cgtcacgctc aagcattgct tgacgacgat gattcatctc agcgatgagg
    21421 gcttcaacag aatcctctag ctgacactcc tttttcatag ttgtccacat atcgtcaaag
    21481 gtggttccca taaactggta ctgatacgct tcattggtat ctatgcctcg gtccaatagc
    21541 atttgtgtct tggttgacaa aaagatatat tctgagtcaa caatcacacc gtccatatca
    21601 aaaataaggc ttgttttcat catctacctc ctcttatgct atatctcagt caggtcaaga
    21661 gcaagactat taattactag agctattttt accagaaaaa agctcaacaa tatctgacag
    21721 ctgactaata tgatgattat catcactatc tggcagcaat aggttgatag agctaatccc
    21781 agctgccctt gctgcagcaa ggtctaaggg cctatcacca atatagtagg tctgcgactt
    21841 atccatctga taatgatgaa tgagaaaaag aagcgcttca gggtccggct tacgcttaaa
    21901 gccacaatct gctgtaatca cctctgtaaa gtaatcagca atccccagac gctgcaaaac
    21961 agcctgagtg gttcgtcctt tatgagtcac aataaaaggc ttaaccccct gctgagaggt
    22021 taaggctaat gtttccttgg ctgtaggcat tagtgctatt aggtgatcac gcgcttcctg
    22081 ctctcgggta aagaaggcca gcaattctga aaaatccagc tgatgtgcct ctgctaacct
    22141 cttcaaaagc tgtccgatgg attcttgaat aatcgtatcc ataacccaag cctcatcaaa
    22201 gggcagctga taggtctgat acaataaacc tagcgcctga cgaatagcct cagaggattg
    22261 gactagagtt ccatcaaagt cccaaatgag attaactgtc acaatcctta cctcttaaat
    22321 caatccaata acgagcaata gcctgccctg ctaagcttgt agtagggtaa tcatctgcca
    22381 cctgaacaat atcctctaaa ataccaccag ccttttcaat ggtttttcga ctggctatat
    22441 tatctttatt agctgttatt aagacacgct tgatcccacg ctcttgatat tgctgtaatg
    22501 caaaggccag caagtctgtc ataattccac gcccgcgata atctgtcctt gtcacatagc
    22561 caatatgtcc gccaattgtt gctaagtctc ctttttccaa ctgccagcga cagcctattc
    22621 tagccactag ctgaccatct aaaaaatagt aataattagt gctagtggac cagtcaggat
    22681 gatcagtttg gacctcaaac cgtctagatt gctcaacaaa ggctgcaaag tcctctactt
    22741 ttttggtctc aacaaaggta ttacctgaag ctttttcagc taacagtata tcctgaaagc
    22801 gcttaaaggc tgcttgatca gctaaagcaa ttgttctaat ctctttcatg cctggctcct
    22861 ttttattatg ctaaaaatca actgggcatt tctcaagcat tcatcatgcc aacgaaaaag
    22921 agctgcccct agaactgttg atgtaatact acgtctagag gctgcccaca ggcctttaag
    22981 ctaggctgat agacactgac tgctgctatt taccaatagc tcaaaaccta agaggagatg
    23041 gcaactatta gagatgtgcc cctcttgcca ctaagtcctc tagctctgtc aaacgctctt
    23101 caaagaccct aaaggctgct tctaggtaat cacccttagc catatcaaca ccagccttgg
    23161 caatcacctc aagcggataa tctgaatttc cagacttcag ataggtcaag tagtgatcaa
    23221 tatcctcttg agtaccatgc acgatcttat cagccaagta gctggctgca gcaaagcctg
    23281 ttgcatattg atagacatag tagttgtaat agaaatgcgg aatgcgagcc cactcatact
    23341 ggataaaatg gttgtcctct ttttttaagc cataatattt ttcgtttaaa tcagcataga
    23401 gattattgag gtattcactt gttaacacct cgccattttg atccgcctga tgaatagcgt
    23461 gctcaaactc agcaaactgt gtttgacgaa aaaccgttcc acgaaaacca tctaggtaat
    23521 gattcaaaat agcaaagcgc tccttatcat cctgcacctc atgtaacaag gcctcagtca
    23581 tgatattttc attagtggtt gaagcaatct cagctaagaa aatgctgtaa tctccataca
    23641 cgtaaggctg tgtttcacgc gtaaaggttg agtgcaggct atggcctgtc tcatgcacta
    23701 gcgtatagag gttatcaagc gtgtcctgcc aatttaagag cataaaggca ttggtatcat
    23761 aggaaccacc agagtaagct cctgagcgtt tgcccttatt gacatgcaca tcaatccaac
    23821 gctctgtaaa ggcacgatgc acacgctctg aataatcctg gccaaaaaca gccaaaacct
    23881 tctctgcttt ttccaaggcc tcatcatagc cgatagcaag atctgtctca gataaaggag
    23941 tataaacatc atacatcttt agatcatcta aaccaagcac ctcttgacgt agcttcaaat
    24001 aacgatgaag cagcggcaaa tgcttattaa cgttttctag tagggtatcg taaacagcct
    24061 ctgggataaa gttggctgac atcgctgcct gacgggctga agcatatttg tgaacacgtg
    24121 ccttataatt ttgcaccttt acattggttt gcagggtttt agcataggtg tgctggaatt
    24181 gctcataagt actatacatg gcttcatagg cagccctacg caccttgcgg tctttcgatt
    24241 ccatcaagct aatgaaatta ccatgtgtta gctcaacctc ttctccctta tcatttgtca
    24301 caataggaaa agcaatgtcg gcattatcta ggatactaaa ggtctcctca gcaccattaa
    24361 agatttcttg tgcccctgct aatagctcct cctcagcctg actaaggaca tgctcacgcg
    24421 tcttgaacaa tttatcaaag aaatggtcat agactgttag ctccggtgtc tcagctaaga
    24481 aggcttggta ggcttcctga cttaaggcca taaattctgg ctcatagaat gaaaaggctt
    24541 cactaaattt agcataaata ccagaggcct tagcttgata ttcttgatac ttggcaactg
    24601 tcgtatcctg atcatttttc atgctagcat aaacataaac cttttcaaca cgacgagcca
    24661 gctccaaatg cagctctgtg atatctaaga gactgctgct tgaatccaac aaatgcccag
    24721 cctgctgcct tgcagcctca attgctgcca gcagactatc tgcctctgtc tcccaagctg
    24781 cgtctgttgc aaaaatagtg cttaaatccc aagtgtactt ttcctctaga tgactacgat
    24841 tatctgtcat acggacctcc taagtttcta ttactaatca ttttaacata atatgctggt
    24901 gaaaaaagct tttgcacctc tttatttgct gcttttgcgt aatatttttc aaagcaatcg
    24961 taatagtggc tcaaatcctc atgaatctgg caaaagccag ctgagcaagc aatcggctta
    25021 acctgtggat aataagcctc taggggccta tcaagcaggt tatccccagc tagataagcc
    25081 tcttcttgct ttttcaacca tttgctatct tttgctagta aggctttttg aatccttctc
    25141 agcaagtgct tatccatctg gagctgatag gctgacaggc cttttctttg gtaaggcagc
    25201 cgcaaaaagg ccaacaaatc atcatctaag gaacaggtct ttactagata gctgacctta
    25261 ccaaataaat cctcatgaat cata
//
LOCUS       DARYXS010000021        24485 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.021, whole genome shotgun sequence.
ACCESSION   DARYXS010000021 DARYXS010000000
VERSION     DARYXS010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24485
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.021"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..165
                     /locus_tag="TV193_000692"
     CDS             <1..165
                     /locus_tag="TV193_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512914.1"
                     /translation="VTYDSLVGQTKRHFDDKVTQARGLATKFKTVKEQLEEGVERTAA
                     IDQKLGCDFS"
     gene            162..554
                     /locus_tag="TV193_000693"
     CDS             162..554
                     /locus_tag="TV193_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512915.1"
                     /translation="MTALEKIRTAIRQKEEELEEQQEHYHQERLQMAAAHDELRGNYN
                     QLQQLYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            574..858
                     /locus_tag="TV193_000694"
     CDS             574..858
                     /locus_tag="TV193_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512916.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALEQAIKTQNRGYSSLM"
     regulatory      1512..1637
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            1710..2288
                     /locus_tag="TV193_000695"
     CDS             1710..2288
                     /locus_tag="TV193_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1512917.1"
                     /translation="MSKTHQLVMVAILSAISFCLMFVGFSIIPGASFLKIDFSIIPIL
                     LGLVLMDLKQANLILAVRTLLRLALNNHGVNDLIGIPMNVIAVALFITAFALIWHRQK
                     GLVTYVLASLVGTGLLTLGMVVMNYVFAIPLYAKFAGFDIKAFIGTARYIFTMVIPFN
                     LLEGLIFAIVFYFVYIAGKPILERYPNSYHET"
     gene            2278..2928
                     /locus_tag="TV193_000696"
     CDS             2278..2928
                     /locus_tag="TV193_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEL1512918.1"
                     /translation="MKHKQQHLLLSSFAMLLFVVLGYIVKFFPEDLTSFDSQLRLALR
                     GHLPEGLTQFFKGITVAGNVSTQAVIVVVAVLALLALSWRAEALFVLSNGVFAALLIW
                     VLKLLYQRPRPSIEHLVHASGYSFPSGHSMGSLLIIGSLLIICHQRLQSASLRWLVDI
                     ALLALILLIGLSRIYLGVHYPSDVLAGYALGFGILQLLYPFYDQKRFEWRFQLKQK"
     gene            3119..4042
                     /locus_tag="TV193_000697"
     CDS             3119..4042
                     /locus_tag="TV193_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623410.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEL1512919.1"
                     /translation="MTKRYQTLNEYYRRLFGAKIFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPEVNQYLVYFQNFTNTHDKLEVIRE
                     RYEQAINEPGVVGINIGTRPDCLPDETIAYLAELSERMHVTVELGLQTTYEATSQLIN
                     RAHSYDLYKETVQRLRQYPNINIVSHLINGLPGETHEMMIENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLLSQKDYVSIICDQLEIIPEHIIIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDLEMERRNSWQGCKLKG"
     gene            4055..4840
                     /locus_tag="TV193_000698"
     CDS             4055..4840
                     /locus_tag="TV193_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEL1512920.1"
                     /translation="MKQRLIAGEELSLPPVLKKLLQNSLVYDSSSSAEARVYAIDKGQ
                     GYFLKTAAKGRLAKEAALTRYCHSKGLATEVLDYISGDQDWLLTAKVAGEDASHIEYL
                     SDPKRLCRILVDHMLKLHSLSLSDFPVADKTLAYIEAAEAGYHQGRFNQCFLPPQQRF
                     QSQEEAYRRIQELKLLLQHETLIHGDFCLPNMILDRWQFQSMIDWGEAGKSDRHIDLF
                     WLIWSLQFNLKTDRYKDYVLDCYGRRHIDLDILDGIAAFEVFA"
     gene            4850..5407
                     /locus_tag="TV193_000699"
     CDS             4850..5407
                     /locus_tag="TV193_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1512921.1"
                     /translation="MIKRPIHVSHEFLKEVLDKQSIAVDATMGNGYDTAFLASLSQRV
                     YAFDVQQQALTKTQERLEQQGLTNAELILAGHEQVDQYVKEPIRAAIFNLGYLPNADK
                     SLITRPETTILALAKILDRLELGGRIAIMVYYGHDGGSREKEELLDYIGQLNQRQVTA
                     MLYQPINQMNQPPFLIMLEKIAATD"
     gene            5535..6869
                     /locus_tag="TV193_000700"
     CDS             5535..6869
                     /locus_tag="TV193_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEL1512922.1"
                     /translation="MEDPVSQPLLIQFLLLVILTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKRYDRLLRVLEQPNNFLSTIQVGITFISLLSGASLSASLGQVISGWLGGSATA
                     QTAGSIISLVFLTYVSIVLGELYPKRIAMNLKDKLAVISAPVIIILGKLVSPFVWLLS
                     ASTNLLSRITPMTFDDADERMTRDEIEYMLTNSEATLDAEEIEMLQGIFSLDEMMARE
                     VMVPRTGAFMIDINDDTLDNIKEILKQSFSRIPVYDVDKDKVIGLIHTKRLLESGFRQ
                     GFENISMRKLLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHHIDDNTYIVTGTMTLNDFNEYFDTELESDDVDTIAGFYLT
                     GIGTIPSQKEKESFACDSKQKHLVLVNDKVKDGRITKLKLTISNIEQNITED"
     gene            6946..7737
                     /gene="pflA"
                     /locus_tag="TV193_000701"
     CDS             6946..7737
                     /gene="pflA"
                     /locus_tag="TV193_000701"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEL1512923.1"
                     /translation="MVEVDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKMRCQYCH
                     NPDTWAMETNQSQRRTVNDVLKEALQYRHFWGKKGGITVSGGEAMLQMDFITALFTEA
                     KKLGIHTTLDTCGFAYRPTPEYHELLETLLAVTDLILLDLKEIDEEQHKLVTRQPNKN
                     ILQFARYLSDRQVPVWIRHVLVPGLTDIDDHLVRLDAFVKTLRNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVENAKKLLHTESYTEYMNRIHQS"
     gene            8237..9172
                     /locus_tag="TV193_000702"
     CDS             8237..9172
                     /locus_tag="TV193_000702"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEL1512924.1"
                     /translation="MSKLLVFGHQNPDTDAIASSYAFDYLAKKAFDLDTEVVALGDPN
                     EETAFALDYFGVSAPRVVTSAKAEGASHVILTDHNEFPQSISDIREVEVYGIVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRLFKENRVDVPKDIAGMLLSGLISDTLLLKSPTT
                     HASDHRVAAELAELAGVKLEEYGMAMLKAGTNLASKSEAELIDIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERKEAIEAAIREVMASEGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFSFKLEDNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            9239..9892
                     /locus_tag="TV193_000703"
     CDS             9239..9892
                     /locus_tag="TV193_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEL1512925.1"
                     /translation="MITIFNPDKLTRQPFFQDLIHYLNQHDDVTLRHIKQAFSHVKGI
                     DKALEAYIQAGYICRKNRRYYLCLPLLDDLQQVTLEDLIFVDRASDLYEALMALVFET
                     VLSNQTNQVLIKEKTTIDRDKLTLANYFYRLRRGEALSDEQLRLYALLGDVNQDYALK
                     YMTSFLLKFARKEIVMQKRTDIFVNALELLGYIEKVEATKYCLKLAFDKEQLIFYAD"
     gene            complement(9997..10995)
                     /locus_tag="TV193_000704"
     CDS             complement(9997..10995)
                     /locus_tag="TV193_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1512926.1"
                     /translation="MTATKRHVPLFLGLISGLVCLMIISLSIGESSMSPLEVVRVLFG
                     KSTADMALIITNIRLPRILAACIGGGSLALSGLMLQSLTRNHLADSGILGINAGAGMA
                     ITLVISYSTSNSLTSRQGLPLMTISGAMATIVLVYLLSLRHGHIDPIRLIVTGVGLST
                     MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKL
                     NIMALNDEASMALGFKLHQYRTIVLALSAILSALSVILVGNITFIGLIAGHTSKRLVG
                     ADHRLSLPVSLFIGMILLLLADTIGRVYLVGSNIPTGILVSIIGASYFLYLMVKMT"
     gene            complement(10992..12017)
                     /locus_tag="TV193_000705"
     CDS             complement(10992..12017)
                     /locus_tag="TV193_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1512927.1"
                     /translation="MTAQHHTKPKLAKAAPPWLILTFISLTLVLAIYCSLRFGAVSLS
                     HQELYHILLGKQDQGQKASIILDIRLPRLILAALVGAALAVSGAIMQGITRNPIAEPG
                     LLGINSGAGLALVIGYAFSPHLHYSTIILLSLLGSLLATLLILSLAYQAGKGYTQMRL
                     ILAGAMISMLLSAIGQGITTYCHLANAIIGWQAGGLIGVNWQMVSYVAPLIICGLALS
                     YLLAYHLTILSLSQEQAKALGQRTFLISLIFIGLVLLLSSAAVAVAGSISFVGLIIPH
                     AITLVTAKDYRWILPLATLLGASFMLWVDFACRNINPPYETPLSALISFIGLPCFLWL
                     VRKGGRF"
     gene            complement(12027..12965)
                     /locus_tag="TV193_000706"
     CDS             complement(12027..12965)
                     /locus_tag="TV193_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1512928.1"
                     /translation="MKKLLLILTVFVTAFTLVACSSQSKQQESTSKASLSHKPKIAGV
                     TYYGDIPVKPKRVVSLAATYTGYLAKLDLHLVGVTSYDKKNPVLTKSITQAKQVAATD
                     LEAITALEPDLIVVGSTEENIDQLAKIAPLISIEYRKRDYLQVFSDFGRIFNKEKETD
                     QWLADWKQKTSDYEKEIKQVTGSAATFTIMGLYEKEIYLFGKDWGRGGEIIHQALHYD
                     APEKVKKEVFKQGYLSLSQEVLPDYIGDYVIVAAEDDQTGSALYESDLWQQIPAVTNN
                     HVIKVNANVFYFTDPLSLEHQLEVLKKAILSTGASQ"
     gene            complement(12990..13769)
                     /locus_tag="TV193_000707"
     CDS             complement(12990..13769)
                     /locus_tag="TV193_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512929.1"
                     /translation="MSTISAERISAGYDQSLIISNLSVTIPEGKVTTIIGANGCGKST
                     LLKTLARLLPLKAGQVLLDGQAIARLATKDVARTLAVLPQLQEATTATVYELVSYGRY
                     PHQSYLGQLSQADKDKICWAMEVTSMAPYAHQAVDALSGGQRQRAWIAMALAQDTDII
                     FLDEPTTYLDMNHQLDILELLKELNQVSGKTIVMVLHDLNLSARYSDHLIAMKNGHIK
                     YSGEVNQVMTPEMIQDIFQVKAQLVTDPLYHCPTLLTYQLI"
     gene            complement(14029..15474)
                     /locus_tag="TV193_000708"
     CDS             complement(14029..15474)
                     /locus_tag="TV193_000708"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEL1512930.1"
                     /translation="MITIEHLLTILKKDHNFREVLDQDGYHFNYSGLQFDSLSYDSRQ
                     ADEQTLFFAKGSAFKADFLRQAIAKGLRLYVSEIDYQVGIPVILVNNIKHAMSLAAMA
                     FYDYPQNKLKLLAFTGTKGKTTAAYFAYHMLKESHKPALLSTMNTTLDGQHFFKSQLT
                     TPESLDLFAMMAQCVANGMTHLVMEVSSQAYLVGRIYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVVVNSGMEHFNILAEQVADKPHDFYGKGACNRLLQRQA
                     FSFQAAGKVAGDYAIQLIGSFNQENAMAAGLACLRLGASLEDIRQGIAKTNVPGRMEV
                     LTMTNQAKVFVDYAHNGDSLEKLLSVVEEYQKGQIYLILGAPGNKGESRRADFGQVIN
                     QHPNVRIILTADDPNFEDPQLISEEIASYIHREVDIIIDRKEAIKTGMERCQNEQDAL
                     IIAGKGADAYQIVKGQKTAYAGDLAIAKSYL"
     gene            15560..17191
                     /locus_tag="TV193_000709"
     CDS             15560..17191
                     /locus_tag="TV193_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEL1512931.1"
                     /translation="MSTEKKQLTQEQLMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQQEHSYQLIRSTLKV
                     MLVLGLIFSVLMYLGSPLFARLSGGDETLVPIMHSLSLAVFVFPVMSVIRGIFQGYKE
                     IKPYALSQIAEQLVRVIWMLLTTFFIMKMGSKDYIAAVTQSTFAAFIGMIASMAVLFY
                     YFWTQGLLKAIFTKTEHAIPIDIKGLLIETLKESIPFIITGSAIQAFQLLDQWTFVNT
                     MTLFTSYTRSQLWVLFGYFNANPAKITMVLIAVAASIGSVGIALLTENYIKKDMRAAA
                     RLIINNIEMLLMFLLPALTGAIILARPLYTVFYGSSEGQAVRLFVAVLCLTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGVFVKLVLQVPLIYLFHAYGPLLATTLGLLVPIYLMY
                     RRLHQVTRFNRKLLHKRILLTVIETALMGLIVLLANWFLGYLFKPTGRLTSLLYLVII
                     GGLGMGVYAYMTLLTRQLDKLIGSRAARYRQKLGL"
     gene            17341..17970
                     /gene="upp"
                     /locus_tag="TV193_000710"
     CDS             17341..17970
                     /gene="upp"
                     /locus_tag="TV193_000710"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEL1512932.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK"
     gene            18201..18791
                     /locus_tag="TV193_000711"
     CDS             18201..18791
                     /locus_tag="TV193_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEL1512933.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELA"
     gene            18896..19342
                     /locus_tag="TV193_000712"
     CDS             18896..19342
                     /locus_tag="TV193_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1512934.1"
                     /translation="MLIINEELFAIEKAIEQLVQDIRTSSQYQAYALAKKAFEADLAL
                     QTELALFEELKQDYELRQDLLKLCPDARALRCQLLHQKRQLDLHPLVADLRLAQVDLQ
                     EVLATISTAIAEAVSEDILVDTGLPLATNRPRHELGPYQNIKEKST"
     gene            19343..19627
                     /locus_tag="TV193_000713"
     CDS             19343..19627
                     /locus_tag="TV193_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEL1512935.1"
                     /translation="MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYIN
                     KEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG"
     gene            19943..20578
                     /locus_tag="TV193_000714"
     CDS             19943..20578
                     /locus_tag="TV193_000714"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEL1512936.1"
                     /translation="MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGG
                     VAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDS
                     SVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLD
                     LEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA"
     gene            20592..21467
                     /locus_tag="TV193_000715"
     CDS             20592..21467
                     /locus_tag="TV193_000715"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEL1512937.1"
                     /translation="MDLAQKAPRVYQAFQEILQKKRLNHAYLFSGDFANFDMALFLAK
                     TLFCEQKRGNAPCHHCRACQLIEHNDFSDVTILEPVGQLIKTDTVKEMMTNFSQTGYE
                     GRRQVFIIKDCDKMHVNAANSILKYIEEPQGDCYMFLLTNDDNQVLPTIKSRTQVFHF
                     PKDEHYLSELAQKKGLLKHQADLLARLAANAQQLTAFSENTRLLELMAQAERFVSIWF
                     QDKEQAYLELNRLVQLAEEKEEQDMALTLLTLILAKDYSRQNAFTYLEAVYQARLMWQ
                     SNVSFQNTLEYMVIS"
     gene            21464..22264
                     /locus_tag="TV193_000716"
     CDS             21464..22264
                     /locus_tag="TV193_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1512938.1"
                     /translation="MISTIGIKYCDTCSVRYVQTDQAFPVQTKLVISDGKGSRLAVVN
                     SPIKSFCKDDLPKDMPSVLRPANDMDYKAYQQNLQLAAQSKQKVAEMIDRNGLDMTLV
                     DIVFSLERRYVLITFTAQERVDFRQLLKDLAAYFKTRIELRQINSREEARVYGGLGPC
                     GRPLCCSSFLGEFPPVSIKMLKHQGLSLHSAKSLGCCGRLLCCLQYEDDFYQESKKKF
                     PDYGTIVRTAQGPGEVAGIDLFTDTIQVRFKDQLALVTYALEEVKVSE"
     gene            22257..22580
                     /gene="yabA"
                     /locus_tag="TV193_000717"
     CDS             22257..22580
                     /gene="yabA"
                     /locus_tag="TV193_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEL1512939.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQGLVEENTILRLE
                     NTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            22585..23451
                     /gene="rsmI"
                     /locus_tag="TV193_000718"
     CDS             22585..23451
                     /gene="rsmI"
                     /locus_tag="TV193_000718"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEL1512940.1"
                     /translation="MQIQKSFKEEKESGVLYLVPTPIGNLEDMTFRAVNVLKEVDIIC
                     AEDTRNTGLLLKHFGIKTKQVSFHEHNAYDKIPDLLDLLLAGRSLAQVSDAGMPSISD
                     PGHELVRAAIDRDITVVALPGASAGITGLIASGLAPQPHLFYGFLPRKAGQQRAFLMT
                     KADYPETQIFYESPYRVKDTLTNLLACYGDRQVVLVRELTKLFEEYQRGQISEVLTYL
                     ADHPLKGECLLIVAGANQADASEPAEDLDLLALVQQAIAAGMKPNQAIKTIAKDYKVN
                     RQELYQQFHGLG"
     gene            23957..24112
                     /locus_tag="TV193_000719"
     CDS             23957..24112
                     /locus_tag="TV193_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1512941.1"
                     /translation="MATEMLASFEGGKNNWAANVSGVIGAGSAGAALGFPVCGVACGS
                     IGVTGGF"
     gene            24171..24371
                     /locus_tag="TV193_000720"
     CDS             24171..24371
                     /locus_tag="TV193_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1512942.1"
                     /translation="MEHYRALAISEMQDISGGNAAGNAVIGGLGGLKTGITFCKIPHP
                     VLKGVCIDGFTALGACLAYKVN"
BASE COUNT         6771 a         4793 c         5863 g         7058 t
ORIGIN      
        1 gtgacctatg acagccttgt gggtcagacc aagaggcatt ttgatgacaa ggttactcaa
       61 gctagaggac tggccacaaa gttcaagacc gtaaaggagc agctagagga gggggttgag
      121 agaacagctg ctattgatca aaagctagga tgcgactttt catgacagca ttagaaaaga
      181 tcagaactgc tatccgtcaa aaggaagagg agctagagga gcagcaggag cactatcatc
      241 aagagcggct ccaaatggca gcagcccatg acgagttaag aggcaactat aaccagctac
      301 agcagctcta tgcctctagc tatcaggccg ttagcagcta cctcagacat tatgatgcta
      361 gtctgataac agaccaatat accgttctaa cgaggctgat tgatgactac cagcaccgaa
      421 cagagcagtg ctatcatgag caaggtcgca agatgtcgca gcaggaggaa gcaattgacc
      481 atcactatcg cagccagcga caggcgatag aaaaggacat cacagcgctg aggcgtcagt
      541 ggcgtgaagg ttaaggaaaa ggagataaga aagatgattg ctatagagat gatcttaacc
      601 ggacaagagc cgatcaggac tttaaagaaa gagctggata ggagattagt tcagtccata
      661 tgtgctccct tgaccttagg tcgccttcat gcccttcaaa ggcgctatga cagtgaggta
      721 tctcggattg ccacagacac cgcagatcat attcagacca ttgtcaatca gctagatagc
      781 agcattagag ggcaaggcag gacagcacta gagcaggcga tcaagacaca gaacaggggc
      841 tatagcagcc tgatgtgaga caagaaggac ttactgtcct accagctaca gtcactacac
      901 tgctagagct tgcggtgtga gcagcagtaa gaagcaaagg cgctgcccta gagggctgat
      961 gaatcaccat caccagtttg gagccattag ctgtgccaaa ggttttctaa agccaaaaag
     1021 aaaaaactcc gattggagtt cagaatgtag gcaaacccta tcagcgatag aaaaattgaa
     1081 catttagaaa ttgactatca tatcatgaaa actctgggaa atgctgatat tacagtattt
     1141 ttcagacttc ttttgttttt ttgattaaaa gaaaaagatt gaagaaaacc gtctaaaatg
     1201 gactttttct tcaatctgaa aactctgatt ggagttttca ttggttaggt gtgtctatga
     1261 ccgtaaaggg gacaacggta gtaataccag agcaggttat tggaggtttc ttctagtctg
     1321 ctcttttttg ccttgagcta ggctagtgcc atgtcacagg gtggcctacc tcgtagagag
     1381 ctttgtagcc tcaaagtgat ttttcttgct gttgctttca tctagctttt ttgcctgatg
     1441 tcttgtgttt gttggaaaag ctaggcttca aaaaaatgtc ttgcgctata ggtttaaatt
     1501 tgctatgcta taagtgtctt cagggcaggg tgtaattccc gaccggcggt gactagtgca
     1561 gctagaagtc cgcgagcgca agctgatgtg gtgtgattcc acaaccgaca gtaaagtctg
     1621 gaagagagaa gaccgggttt ttgagttgac tttttgcctg ctcatacgaa ggagcttctt
     1681 tcaatttgtc aaaattggag gaatttttta tgtcaaaaac acatcaactg gtgatggttg
     1741 ccattctttc agccatatcc ttttgcctga tgtttgtggg gttttccatt attccaggag
     1801 ccagcttttt aaagattgat tttagtatca ttccgatttt gttaggcttg gtcttgatgg
     1861 atctaaagca agctaacttg attttagcgg tgaggacctt gcttagacta gccttaaaca
     1921 atcatggcgt taatgatttg attggtatac cgatgaatgt tatagcagtt gcgcttttta
     1981 tcactgcctt tgccttgatt tggcatcgtc agaaagggct ggtcacctat gtactagcta
     2041 gtcttgtggg gacagggctg ttaacgcttg gtatggttgt catgaactat gtctttgcta
     2101 ttcccttata tgccaagttt gctggctttg atattaaagc ttttattggt actgctcgct
     2161 acatatttac aatggtcatt cctttcaacc ttttggaggg gctaatattt gcaattgtct
     2221 tttatttcgt gtatattgca ggtaaaccaa ttttagagag atatccgaat tcatatcatg
     2281 aaacataaac aacaacatct gctattgtct tcctttgcta tgctactatt tgtggtgctt
     2341 ggctatattg ttaaattttt tcccgaagac ctaacgtctt ttgatagtca gcttcggtta
     2401 gccctaagag gtcatctgcc tgaagggcta acccagtttt ttaaagggat cactgtagct
     2461 ggaaatgtta gtacacaggc agtgattgtt gttgttgctg tgctggcttt attggccttg
     2521 agctggagag ctgaggcctt atttgtccta tcaaatggtg tttttgcggc ccttttgatt
     2581 tgggtgctaa agctcttgta tcaaagacca agacccagca ttgagcattt ggtgcatgct
     2641 tctggctatt cttttccgag tggccattcg atgggaagcc ttttgattat tggaagtctg
     2701 ctgattattt gccatcaaag attgcagtca gcctccttac gctggctggt tgatatagcc
     2761 cttttggcct tgattttgct gataggcttg tcacgcattt atctgggagt gcattatcct
     2821 agcgatgtgt tggctggcta tgccttaggc tttggcatac ttcagctgct ttatcctttt
     2881 tatgatcaaa agcgctttga atggcgtttt cagctaaagc aaaagtaaat ccagtgatca
     2941 gtcagctgta tggcgcgtta cagatcagtt ctagaaaagc tagtgattga aggcaggtct
     3001 cttccagagg tcttcttcaa tcctttttag ttgccttgct ttggctcatc aatcagagaa
     3061 gtagcagcca attgagatct tctgctgtta atcgggggat ttgtgctaca atagaggcat
     3121 gacaaaaaga tatcagacct taaatgagta ttatcgtcgt ttatttggtg ctaaaatttt
     3181 caaggtgccc attgatgctg gctttgactg tcctaatcgt gatgggacag ttgctcatgg
     3241 tggctgcacc ttttgtaccg tttctggctc aggtgatgcg attgtggcgc ctgatgcacc
     3301 tatcagggaa caattttaca aagaaattga ttttatgcat cgcaagtggc ctgaggtcaa
     3361 tcagtatttg gtttattttc aaaattttac caatacgcat gataagctag aggttattcg
     3421 cgagcgctat gagcaagcaa tcaatgagcc tggcgttgtt ggtatcaata tcggaacaag
     3481 gcctgattgt ttgccagatg agacgattgc ttatttggct gagctatcag agcgcatgca
     3541 tgtgacagtg gagcttgggc tgcaaacaac ttatgaagcc acctcccagc tgattaatcg
     3601 ggcgcattct tatgacttgt ataaggaaac ggttcagcgt ctgaggcagt accctaacat
     3661 taacattgtg tctcacttga ttaatggctt gcctggtgaa acccatgaga tgatgatcga
     3721 aaacgttaga cgctgtgtca cagacaatga tattcaaggc attaagctgc atttgctgca
     3781 cctgatgacc aatacgcgta tgcaaagaga ctatcatgag ggacgcttgc agctcttgag
     3841 tcagaaggac tatgtatcga ttatctgtga tcagctagaa atcatacctg agcatatcat
     3901 tattcatcgc atcacaggtg atgcgcctag ggacatgctg attggtccca tgtggagcct
     3961 gaataaatgg gaggttttga atgcgattga cctagaaatg gaaagaagaa atagctggca
     4021 gggctgtaag cttaagggat aatcggggga agcaatgaaa caaagattga tagcaggaga
     4081 ggagctgagc ctaccacctg ttttaaaaaa actgttacaa aacagtttgg tttatgatag
     4141 cagtagctcg gcagaggcac gtgtttatgc tattgataaa gggcagggct attttctaaa
     4201 aacagccgct aaaggtaggc ttgccaagga ggccgcccta actcggtatt gtcatagtaa
     4261 gggcttagca acagaggtgc ttgattatat cagcggtgat caggattggc ttttaaccgc
     4321 aaaggtagca ggagaggacg ccagtcatat tgaatatttg tccgatccca agcgcttatg
     4381 tcgtatctta gttgatcata tgctaaagct gcatagcctg tctttgtctg attttcctgt
     4441 agctgacaaa acgctagcct atatcgaagc tgctgaggct ggttatcacc aagggcggtt
     4501 caatcagtgc tttttaccgc ctcagcaacg gtttcagtcc caggaggagg cttacaggcg
     4561 gattcaggag cttaagctct tgttacagca tgaaactctg attcatgggg atttttgttt
     4621 gccaaatatg atcttggatc ggtggcaatt tcagtccatg attgattggg gggaggcagg
     4681 aaaaagcgat cgacatattg atcttttttg gctgatctgg tcgcttcaat tcaatctaaa
     4741 aacagatcgg tataaagatt atgtgctaga ttgttacggc cgaaggcata ttgacttaga
     4801 catactagat ggtatcgcgg catttgaagt atttgcttag gaggataaga tgataaagcg
     4861 tcctattcat gtatcacatg aatttttaaa agaagttttg gataagcaga gtattgctgt
     4921 tgatgctact atgggaaatg gctatgacac tgccttttta gcaagtctgt cacaaagggt
     4981 ttatgctttt gatgtgcagc agcaggcact gaccaagaca caagagcgct tggagcagca
     5041 aggcttgact aatgcagagc ttattttagc tggacacgag caggtggatc aatatgttaa
     5101 ggagcccatt cgggcagcca tttttaatct gggctatcta cccaatgcag ataagtcgtt
     5161 gatcacaagg cctgagacga ccatattagc cctagctaaa atacttgatc ggcttgagct
     5221 aggtggacgg attgctatca tggtgtatta tggtcatgat ggcggtagta gggagaagga
     5281 agagcttttg gactatattg gtcagctcaa tcagcgccag gtaacagcaa tgctctatca
     5341 gccgatcaat cagatgaatc agccgccatt tttaatcatg ctggaaaaaa tagcagctac
     5401 tgattaagct tcagccagcc ttatgtcagg gcttagactg tctgtgattt ctcaggaaaa
     5461 agaaataaat cagcaatctt tggcgacaat tgtgatataa tgaagtagta tattatgttt
     5521 taggagttat attaatggaa gaccctgtga gtcagccttt attgattcag tttttattgt
     5581 tagtcattct aaccttgtta aatgcctttt tctcagccag tgagatggct ctggtatcct
     5641 taaatcgctc tcgtgtggag caaaaggctg ccgatgggga taagaggtat gatcgcttgc
     5701 tgcgtgtttt agagcagccc aataactttt tatcgaccat tcaggttggt attaccttta
     5761 ttagcctctt gtcaggggcg agcctgtcag cctctttagg gcaggttatt tctggctggt
     5821 taggtggttc tgcgaccgct caaacagctg gtagcattat ttctttggtg ttcttgacct
     5881 atgtctcgat tgttttggga gagttatacc ccaagcggat agctatgaat ctaaaagaca
     5941 agcttgctgt gatttctgcc ccagtgatca ttatcttggg gaaattggtt agtccctttg
     6001 tttggctctt atcggcgtcg acaaatttac tgagccggat taccccaatg acctttgatg
     6061 acgcagatga gcgcatgacg cgtgatgaga ttgagtacat gctgactaac agcgaggcaa
     6121 cgcttgatgc cgaagagatt gaaatgctgc aggggatttt ctcgcttgat gagatgatgg
     6181 cgcgtgaggt gatggttcca aggacaggtg ccttcatgat tgacattaac gatgatacgc
     6241 tagacaatat caaggaaatc ctaaagcaga gcttctctcg tattccagtt tatgatgttg
     6301 acaaggacaa ggtgatcggc ttaattcata ccaaaaggct tttagaatca ggctttcgtc
     6361 agggctttga aaacatcagc atgagaaagc ttctgcagga gccgctcttt gtaccagaaa
     6421 cgatttttgt agatgatttg ttgaggcaat tgcgaaatac tcaaaaccag atggctatcc
     6481 tacttgatga gtacggaggg gttgcaggtt tggtgacgct tgaggatttg cttgaggaaa
     6541 tcgttggtga gattgatgat gagacagaca aggctgagca atttgttcat cacattgatg
     6601 acaacaccta tattgtcaca gggacaatga cgctcaacga ctttaacgag tattttgaca
     6661 cagaattaga aagtgatgat gtcgatacca tcgcgggctt ttatttgaca gggattggta
     6721 ccattccaag tcaaaaggag aaagagagct ttgcctgtga tagcaagcaa aagcatctgg
     6781 ttttggtcaa tgacaaagta aaggacggtc gtatcaccaa attgaaactt actatttcta
     6841 atatagaaca gaatattact gaagactagg cattgagctt agtctttttg atgaaacatg
     6901 atataatgaa aacgtaaaac catttacaag ggtgaaggag acacaatggt tgaagtagat
     6961 tatgggcaag taactggaat ggtgcattct acagaaagct ttggttctgt tgatggtccg
     7021 gggatacgtt ttatcatttt tttgcagggc tgcaagatgc gttgccagta ttgccataat
     7081 ccggacacct gggctatgga aaccaatcaa tctcaacgcc gaaccgttaa tgatgtccta
     7141 aaggaggctc tgcaatatag gcacttttgg gggaaaaagg gtggaatcac tgtgtcaggt
     7201 ggtgaggcta tgctgcaaat ggactttatc actgcgctct ttactgaggc caaaaagcta
     7261 ggtatccata caacgctaga tacctgtggc tttgcctatc gtccaacccc tgaataccat
     7321 gagctgttag aaacattatt agcagttact gatttgattt tgctggactt aaaggagatt
     7381 gacgaggagc agcataagct tgtcacccgt cagcccaata aaaatatcct gcagtttgct
     7441 cgctacctct ctgataggca ggtgcccgtc tggattcgcc atgtcttggt gcctggcttg
     7501 acagacattg atgatcactt ggtacgctta gatgcgtttg tcaagacctt gagaaatgtc
     7561 gacaagtttg aggtactccc ttatcatacg atgggagagt tcaaatggcg cgagttaggg
     7621 attccatacc agcttgaggg cgttaagcca ccaaccaagg agcgggtgga gaatgccaaa
     7681 aagctgctgc atacagaatc ctatactgaa tacatgaacc gtattcatca atcataggct
     7741 aagctagagt tgggaaatgc ccagcttttt ttggccccat gtcaactgta gtgggtgact
     7801 gataactaag cacgagacga agctcgtttt ctcttgtgtg atgtgcaaag cgaggtaaat
     7861 gggctctata atttctgtag tgggtaaatc caccatggaa attatagagc cgtttttttg
     7921 ctgatgaagc ggctggcttg atgagacctt cagtgttttt aagcgagctc agacacgtgc
     7981 caaaaagtaa tccttgaagc attaaaccaa tcaaggacag tgtattgtcc ccaaatagct
     8041 gaatagctca ttatagaagg cattgctttt tggactggct tgcctgttct tgtgtgtttg
     8101 acaggactct ttaatacctg agattctgtg cccttatgcc ctttagactc ttggcctgtg
     8161 actggggaat cttctttgat tttagagcct atttctgcta caataagatg aataaagaga
     8221 atgaggtaga aactttatgt caaaactatt agtttttggt catcaaaatc cagatactga
     8281 tgccatcgca tcatcgtatg cttttgacta cttagcaaaa aaagcctttg atttggatac
     8341 ggaggtagtc gctctgggtg acccaaatga agaaacagcc tttgcccttg actattttgg
     8401 ggtatcagca ccaagagtgg tgacatcagc aaaagcagag ggtgctagtc atgttattct
     8461 aacagaccat aacgaatttc cacagtctat ttcggatatt cgtgaggttg aggtgtatgg
     8521 tattgttgac caccatcggg tggctaattt tgagacagca aatccgcttt atatgcgtgt
     8581 cgaacctgtt ggctctgcct catctattgt ttaccgcctg ttcaaggaaa atagggttga
     8641 tgtgccaaag gacattgcag gcatgctttt gtctggcttg atttctgata ccttgctgtt
     8701 aaaatcacca acaacgcatg cttcagatca tcgtgttgct gcggaattag cagagttagc
     8761 aggagttaag ctagaggaat acggtatggc tatgctaaag gccggaacaa accttgcaag
     8821 taaatcagaa gcagaattga ttgatattga tgctaagacc tttgaattaa atggcaacgc
     8881 agttcgtgta gcccaggtca ataccgttga cattgcagag gtgttagagc gcaaggaggc
     8941 tattgaggcc gctattagag aggtgatggc aagtgagggc tattctgatt ttgtcttgat
     9001 gattacagat attgttaatt caaattcaga gattttggcg cttggtgcga atatggataa
     9061 ggttgaggca gcctttagct ttaagcttga ggataatcat gctttcctag caggtgctgt
     9121 atctcgtaaa aagcaggttg tccctcaatt aactgaaagc tttggagcat agagcttgcc
     9181 tgtagagggg tgttgatttt tatcagcagc cctttggtct ttttgctata atagtagtat
     9241 gattaccatt tttaaccctg ataaattaac gcgtcagcct ttttttcaag accttattca
     9301 ttacctcaat cagcatgatg acgtaaccct gcgtcacatt aagcaggcct tttctcatgt
     9361 taaggggatt gataaggcgc ttgaagctta cattcaggct ggctatatct gtcgaaaaaa
     9421 cagacgctac tatctgtgtc tgcccttgct agatgacctg cagcaggtga cattagaaga
     9481 tctaatcttt gtggataggg catcagatct atatgaagct ttgatggcct tggtgtttga
     9541 gacagtgctg tctaatcaga ccaatcaggt tttgatcaag gaaaaaacaa ccattgaccg
     9601 agataagctg acgcttgcca attattttta ccgcttaaga agaggggaag ccctatctga
     9661 tgagcaatta aggctctatg ccctattagg tgatgtgaat caggactatg ccttgaagta
     9721 catgaccagc tttcttctaa aatttgctag aaaagagatt gttatgcaaa agcggacaga
     9781 tatttttgtg aatgccttgg agcttctagg ctatattgaa aaagtagagg ccactaaata
     9841 ctgcctgaag ctggcttttg ataaggagca gctgattttc tacgctgatt aagagttgac
     9901 ttgatgaata aaaaatggct tagacccaca ctgtaaaaca gttgagtcta agccatttat
     9961 gcttgctgag ccctttaagc tatgcagcag aggctcttat gtcattttga ccatcagata
    10021 gagaaaatag gatgcaccaa taattgagac aagaataccg gttggtatat tgctgccgac
    10081 gagatagact cgtccgatag tgtcagccaa gagaagcaga atcatgccga tgaaaaggct
    10141 gacaggcagg cttaatcggt gatcagctcc cactagtcgt ttgctggtat ggcctgctat
    10201 cagaccaata aaggtgatgt ttccgaccaa aataacactt agggctgaga gaatcgcaga
    10261 tagtgcaaga acaatggtac ggtactgatg gagcttgaag cctagagcca tgcttgcttc
    10321 atcatttaat gccatgatgt tgagcttata ggcttgacta aaggctagca gccaagtgat
    10381 ccccaataag ggagcaacaa tgcttagctt ggaccaatca tcgcctgtta gctgcccgct
    10441 tagccaatga atcacataat ccaccttata acggttcaca ttgccgacaa aggcaatcat
    10501 caggctagat agcatggttg atagccctac gccagtgaca atcagccgaa taggatcaat
    10561 atggccatga cgaagtgaga gcaggtagac caagacaatg gttgccattg ccccggatat
    10621 ggtcataagc ggcagccctt gcctgctggt cagactgtta ctagtgctgt aggatatgac
    10681 aagggtaata gccataccag caccagcatt aatgcctagt atgccagaat ctgccagatg
    10741 atttcgcgtt aagctttgca gcattaagcc agaaagggcc agtgagccgc caccgataca
    10801 ggcagctaaa attcttggga gtctaatgtt ggtgatgatc aaggccatat cagcagtgga
    10861 tttaccaaaa agcaccctga cgacctccaa tggtgacatg ctagattccc caatagacaa
    10921 ggaaataatc atcaaacaga ccagtccaga gattagtcct agaaataatg ggacgtgtct
    10981 tttagtagct gtcaaaagcg acctcctttt ctaactagcc ataaaaagca gggcagccca
    11041 ataaagctga tcaaagcaga tagcggtgtt tcataggggg gattgatatt ccgacaggca
    11101 aagtctaccc aaagcataaa gctggctcca agaagagtag ctagcggcag gatccagcgg
    11161 taatccttag cagtgactaa tgtgatggca tgagggataa tcaagccgac aaaggaaatg
    11221 ctgccggcta ctgctacagc agcagaagac agaagcagca caagtccaat aaagataagg
    11281 ctaatcaaga aggtgcgttg ccctagggcc ttggcctgct cttgacttaa gcttaaaatg
    11341 gtcaaatgat aggctagcag ataagatagg gctaagccac agatgatgag tggcgcaaca
    11401 tagctaacca tctgccaatt gaccccgatc aatcctcccg cctgccagcc aataatggca
    11461 ttggctaggt gacaataagt tgttattcct tgtccgatag ctgacagtag catagatatc
    11521 atcgctcctg ctaaaataag cctcatttga gtgtagccct taccagcttg ataggctagg
    11581 ctgagaatta atagggtcgc taagagtgac cctagcaagg aaagtaatat aattgtcgaa
    11641 taatgaagat gaggggaaaa agcatagccg atgactaatg ccagcccagc tccagagttg
    11701 attcccagta agccaggctc ggcaatggga tttctggtaa tgccttgcat gatagctcct
    11761 gaaacagcaa gtgcagcacc aactagagct gctaaaatca agcggggcag gcgaatgtcc
    11821 aaaataatgc tggccttttg accctggtcc tgctttccaa gtagaatatg atagagctcc
    11881 tgatgtgata gtgacacagc cccaaacctc agactgcagt aaatggcaag cactagagtt
    11941 aagctgataa aggttaagat cagccaagga ggagctgctt tagctagttt aggcttagta
    12001 tgatgttgag ctgtcatctt aagtttttat tgacttgcac cagttgagag gatagccttt
    12061 tttagaacct caagctggtg ctccagtgac agtgggtctg tgaagtaaaa gacattagcg
    12121 ttgaccttga tgacatgatt gttggtcaca gcagggatct gctgccaaag gtcgctctca
    12181 tataaggctg agccggtttg gtcatcctca gcagcaacaa tcacataatc accaatataa
    12241 tctggtagaa cctcctgtga taaggacaga tagccctgct taaacacctc ttttttcacc
    12301 ttttcgggag catcataatg taaggcctga tgaataattt caccacctct tccccagtcc
    12361 ttaccaaaaa ggtaaatttc cttttcatag agccccatga ttgtaaaggt agcagctgat
    12421 ccggtgactt gttttatttc tttttcatag tcacttgttt tttgtttcca gtcggccaac
    12481 cattggtcag tttccttttc cttgttaaaa atacggccaa aatcagaaaa cacctgcaaa
    12541 taatcacgct tgcggtattc aatggagatt agtggtgcga tttttgctag ctggtcaatg
    12601 ttttcttctg ttgagccaac aacaatgaga tcaggctcta gtgctgtaat agcctctagg
    12661 tcagtagctg ccacctgctt ggcttgagta atgctttttg ttaaaacagg gttctttttg
    12721 tcgtaggagg tgacaccgac cagatgaagg tctaattttg ccaagtaacc agtatatgta
    12781 gctgctaagc taaccacgcg ctttggcttg acaggaatgt caccataata ggtcactcca
    12841 gcaatttttg gcttgtggga taggcttgct ttgctggtgc tttcttgttg cttgctttga
    12901 cttgagcagg cgactaatgt aaaagctgtc acaaaaacag ttaaaataag cagtagtttt
    12961 ttcatgtatt ctattctcct agaataaatt tatatcagct gataggtcag caatgtaggg
    13021 caatgataga gaggatcagt gacgagctga gcctttactt gaaaaatgtc ttgaatcatc
    13081 tctggcgtca tcacctggtt gacctctcca gaatatttga tatgtccatt tttcatggcg
    13141 atcagatgat ccgagtagcg tgctgaaaga tttaaatcat gaaggaccat cacgattgtt
    13201 tttccagaga cctgattgag ctcctttagt aattctaaaa tatcgagctg atgattcata
    13261 tctaagtagg ttgttggctc atctagaaaa ataatatcag tatcctgtgc taaggccata
    13321 gcaatccagg ccctttgacg ttggccgcct gacagggcat caacagcctg atgagcatag
    13381 ggtgccatgc ttgtgacctc cattgcccag caaatcttat ccttatcagc ttgactgagt
    13441 tgtcctaggt aggattggtg gggataacgc ccataagaaa ccagctcata gacagtagct
    13501 gtagtagctt cttgcagctg aggtaaaact gctagtgttc tggcaacgtc cttggttgct
    13561 agtctagcaa tggcttgtcc atctaagaga acctgccctg ctttgagtgg caatagtcgt
    13621 gccagagtct ttaaaagggt tgacttccca cagccattag caccgatgat ggttgttacc
    13681 tttccttcgg gaatagtgac agataagttg ctgatgataa gcgattgatc atagccagct
    13741 gaaatcctct cagcactgat tgttgacatg gtttttctcc tttctaatag tcaagcaaag
    13801 ccagctagca aaattctaag gggctgatag cctatgaaat gctagtcgct tttttggtct
    13861 gactataata gtgcgctttc tcttaaaagc tatcccatta tagcatagaa aaaaggccta
    13921 aaaaagcctt tcagaatcta attactgagt ttatgctaaa aaaggagcca gcttagaatc
    13981 attatcagta atcttaagaa ttattactgt ttagcctgtt agaccagtct ataggtagct
    14041 ctttgcaatc gctaaatcac ctgcataggc agtcttttgt cccttgacaa tctgataagc
    14101 atcagccccc ttgccagcaa taatgagtgc atcctgctca ttctgacagc gctccatacc
    14161 agtcttgatt gcttctttac ggtcaatgat aatatcaacc tcgcggtgaa tatagctagc
    14221 aatctcctct gaaatcagct gtgggtcctc aaaattagga tcatcagcag tcagaataat
    14281 acgaacattg gggtgctggt tgatgacttg cccaaaatca gcccgacggc tctcgccttt
    14341 attgcccggt gctcctagaa tcaagtaaat ctggcctttc tggtactctt cgacaacaga
    14401 taggagcttt tcaaggctat caccgttatg tgcataatca acaaatacct tggcctgatt
    14461 ggtcatggtt aagacctcca tgcggccagg gacgtttgtc ttagcaatgc cttggcggat
    14521 atcctctagg cttgccccca gtcgaagaca ggctagtcca gcagccatag cattttcttg
    14581 attgaagctg ccaattaatt gaatcgcata gtctccagct accttgccgg ctgcttgaaa
    14641 tgagaaggcc tgccgctgca gcagcctatt gcaagcccct ttgccataaa aatcatgagg
    14701 cttatcagcc acctgctctg ctaggatatt aaaatgctcc ataccgctat tgaccacaac
    14761 agctcggcta ttttccatta agagccgctt atggtaaaaa taatcctcaa agcttgggtg
    14821 ctcgattggt ccgatgtgat cggggctaat attaagaaag acaccgacat caaaggttaa
    14881 gccgtagata cgcccgacca agtaggcttg actagagacc tccatcacca aatgcgtcat
    14941 gccattagcc acacactgag ccatcatcgc aaataaatca agactttcag gtgtggttaa
    15001 ctgcgattta aaaaagtgtt ggccatctaa ggtcgtgttc attgtagaga gcagggcagg
    15061 cttatgagat tcctttagca tatgataggc aaagtaggca gcagttgtct tgccctttgt
    15121 tccggtgaag gctaatagct tgagcttatt ttgtgggtaa tcataaaagg ccatcgcagc
    15181 taggctcata gcgtgcttaa tattgttaac aagaataaca gggatcccta cctgatagtc
    15241 aatctctgaa acatagagtc ttagtccctt ggcaatggcc tgtctcaaaa agtcagcctt
    15301 aaaagctgat cccttagcaa aaaagagcgt ctgctcatct gcttgtctgc tgtcgtagct
    15361 aaggctgtca aactgtagac cgctatagtt aaagtggtag ccgtcttgat caagaacctc
    15421 tcggaaatta tggtcctttt ttaaaatggt taataagtgc tcaattgtta tcatagcctt
    15481 attttatcct taatgttctt gttttacaag tcacaagcaa aagtttataa taaagctata
    15541 aaaactagga agaacggata tgtcgacaga aaaaaaacaa ttgacacaag aacagctgat
    15601 ggttcaggga gcagcctggt ccaccgcagg taattttatt agccgacttt taggcgttct
    15661 atatattatt ccatggtaca tatggatggg gcagtatgcg atacaggcaa atgcgctctt
    15721 taatatggga tacaatgtgt atgcctattt tttgttgatt tcgacaacag ggctaaatgt
    15781 tgccattgct aagcaggtcg ctaagtacaa ctcgatggga cagcaagagc atagctatca
    15841 gctcattcga agcactctaa aggttatgct ggtattaggc ttgattttct cagtgctgat
    15901 gtatctggga tctccgctct ttgctcgctt gtccggtggt gatgagaccc ttgtcccgat
    15961 tatgcatagc ttatcattag ctgtttttgt ttttccagtg atgagcgtga ttagggggat
    16021 ttttcagggc tataaggaga ttaagcccta tgctcttagc caaattgctg agcagctggt
    16081 tcgtgtgatc tggatgcttc taacaacctt tttcatcatg aaaatggggt ctaaggacta
    16141 tattgcagct gttacgcagt ccacctttgc tgcttttatt ggaatgatag ccagtatggc
    16201 ggtgctcttt tattatttct ggacgcaggg ccttttaaag gctattttta ccaagacaga
    16261 gcatgcgatt cctattgaca tcaagggctt gcttattgaa acgttaaagg agtcgattcc
    16321 ctttattatt acaggaagtg cgattcaggc ctttcagctc cttgatcagt ggacctttgt
    16381 caatacgatg actctgttta ccagctacac gcgttctcag ctctgggtgc tgtttgggta
    16441 ttttaacgcc aaccctgcta aaatcaccat ggtgctcatt gcagtagccg cttcaattgg
    16501 tagtgttggt attgccttat tgacagaaaa ttacattaaa aaggacatgc gagcagcagc
    16561 gcgcctgatc attaacaaca ttgaaatgct gctgatgttt ttattgcctg ctctgacagg
    16621 agctattata ctggcaaggc ctctttatac ggttttttac ggtagtagcg agggacaggc
    16681 tgttaggctg tttgttgctg tgctttgcct taccctattg atggccttgt atacgctttt
    16741 ttctccgatg ctgcaggccc tgtttgaaaa ccgtaaggcc atctattatt ttgcttatgg
    16801 tgtttttgtc aagctggttt tgcaggttcc tttgatctat ctgtttcatg cttatggtcc
    16861 tttgttagct acgacccttg gcttgctagt gcctatctat ctcatgtacc gtcgtctaca
    16921 tcaggtcaca cgatttaacc gtaagctgct gcataagcgt atattactaa cggtgattga
    16981 gacagcattg atgggcctga ttgtgctact agctaactgg tttttgggct atttgtttaa
    17041 gccgacaggc agattgacta gcctgcttta cttagtgatt attggtggct tgggaatggg
    17101 tgtttacgcc tacatgacgt tattgacgcg tcagctggac aaattaattg gcagcagagc
    17161 agctaggtat cgccaaaaat tgggactttg acacccaaga tcaaggcagc tgaagcaggc
    17221 agctagctga tcagattctt gcttttatca tttcaaccgg atctgaaaaa agtaagcaag
    17281 gttttcaatt ttttggtata atagcaaaag tgtaaaaaat aaagaaggaa gtacgtcatc
    17341 atgggaaaat gtcaggttat ttcgcatcca cttattcagc ataagctatc aatcctgcgt
    17401 cgtcaggata cctcaaccaa ggattttaga gagctggtca atgaaattgc aatgcttatg
    17461 ggctacgagg tttctcgtga cttgccatta gaggatgttg agattcaaac accggttgcc
    17521 aagacggttc aaaagcagtt agcaggtaaa aaattagcaa ttgttccgat tcttagagct
    17581 ggtattggta tggtggatgg ctttcttagt cttgtgccag ctgccaaggt tggtcacatc
    17641 ggtatgtatc gtaacgagga gaccttggag ccggttgaat atttggtgaa gctgccagag
    17701 gatattgatc agcgccaaat ttttattgtt gatccgatgc tggctactgg cggctctgct
    17761 attcttgcag tggattcact gaaaaagcgt ggggctgcta atattaagtt tgtgtgtctg
    17821 gtagcagcac cagaaggggt taaaaagctt caggaggctc acccagatgt tgacatttat
    17881 accgcagccc ttgatgaaag attaaatgat catggctaca ttgttcctgg tcttggagat
    17941 gctggtgatc gcttatttgg taccaagtaa aaggctacag gctttggttg tgctaggctc
    18001 tgcttgctag aggctagcct gctaaagcta ataagacttt ctagtttagg ctggaaggtt
    18061 tttaaaagca agtttatcat ttgacctttt ttgaccaaga gattataata aggtcaatca
    18121 ttataaaaag atgtgtttga ctgcctgtca ctgcatgagg cagagtggtg ttagacagtc
    18181 acgatagatt ggagattttt atgattcctg tagttattga acaaaccagt cgtggagagc
    18241 gttcttatga catttattca cgtctgttaa aggaccgtat tatcatgctg actggtccag
    18301 tagaggataa tatggcaaac tctgttattg cgcagctctt gtttttagat gcccaagaca
    18361 acacaaaaga tatttacctc tatgtgaata ccccaggagg ctctgtatca gctggtttag
    18421 ctattgttga tacgatgaac tttattaagg cagatgtgca aaccattgtt atgggtatgg
    18481 ctgcttctat gggaaccgtt attgcttcat caggtgcaaa gggcaagcgc tttatgcttc
    18541 caaatgcaga atatatgatt caccagccta tgggaggcac aggaggtggt acgcagcaga
    18601 cggatatggc cattgctgct gagcatttat taaagacacg tcaccgcctg gaaaagattt
    18661 tggcacaaaa tgccggtaaa acgatcaaac aaatccataa ggacgctgag cgtgattatt
    18721 ggatgagcgc agaagaaacc ctagcctatg gctttattga tgaaatcatg gaaaataatg
    18781 agctagctta gagagcttag taaaatagct taacagcttc tgaaacaaat tgtttcaggg
    18841 gctttttgca tgctaaagag ggctatcttc cttaaaatta tggtataatt aacctatgct
    18901 aatcataaat gaagaattgt ttgccattga aaaggctatt gagcagctgg ttcaggatat
    18961 taggacaagc agccagtatc aggcctatgc cttggctaaa aaggcttttg aggcagattt
    19021 ggccctacag accgagttag ccttatttga ggagcttaag caggattatg agcttaggca
    19081 ggacttgctt aagttgtgtc cagatgctag agcgttgcgc tgccaattac ttcatcaaaa
    19141 gcgccagctt gacctgcatc cattggttgc tgatctgcgc ttggcacagg ttgatttgca
    19201 ggaggttttg gcgacgattt cgacagctat tgcagaagca gtgtctgagg atattcttgt
    19261 cgacacagga cttcccttgg cgacaaatag acctcgacat gagcttggac cgtatcaaaa
    19321 tataaaagaa aagagtacct aaatgtttca aaaacagcag agaattgggc tggttatcta
    19381 cctgtattac aatcgagacg ctagaaaagt gatgaaatat ggtgacttgt actaccattc
    19441 caggcgttct cgataccttg ttatttacat caataaagag gacatggaag aaaagctaaa
    19501 ggacattagt cggctaacat ttgtcaaaga ggtgaaggta tcagcctttg atgacattga
    19561 ttgtgatttt gttgggaatt tacatcgtga gcctctagag cctcaagccc tacctgagca
    19621 gggctaagta ggcctgatcc tgtcttatat agcatgtctt agctcatcaa ttgctcaaag
    19681 ctgatggatc agccctgctg gcttgcttag gcaaagaaaa taagagctga gacgattgtc
    19741 atttatcgag tggctgctca taggctttga ggtgtgaggc acaagtctta ggctgctgct
    19801 ttgagggctg gctttttatt cctatcgcct aaaaggcagc acaaaaaggc ttttttctga
    19861 tctggcactg cccaatgaat tggcagtgct ttttcaggca aattttggta aaatagaggt
    19921 aacgataaac aaaggaataa agatgactag aggaaaatta ataacgtttg aaggtccaga
    19981 cggagcagga aaaacaacgg tgctggaaag actggtgcca ctcttacagg cagctctagg
    20041 acaaaccatt gtaacaacga gagagcctgg aggcgttgcg attgctgaga agattcgtca
    20101 gctgatctta gatgtcagtc acacgaccat ggacgataaa acagagctgc tgctctatat
    20161 tgcagcaaga aggcagcatt tggttgaaaa gatcatgcca gctcttgagt caggacactt
    20221 ggttttggtg gatcgtttta ttgacagttc agttgcttat caaggcgccg gaagagggct
    20281 ggataagcaa gccattcaat ggctcaatca ttttgcaaca gatggtgttg accctgattt
    20341 aaccctgtat tttgatgtgc cctcagagct tggattggca aggattgcac aaaatactga
    20401 gcgagagatc aatcgtcttg atcttgagca attagatttg caccagcgtg ttcgtaaggg
    20461 ctatctggag ctggctttgg aaaatcccca gcgtattgtc aagattgatg catcacagga
    20521 cttagaaagc gttgtgtcag cggctttagc tgccattatc acacacagtc aagcatagca
    20581 ggaggttagg aatggatttg gctcaaaagg ctcctagggt ctatcaggcc tttcaagaga
    20641 ttttgcaaaa aaaacgtcta aatcatgcct acctcttttc aggtgatttt gccaattttg
    20701 acatggctct ttttttagcc aagactcttt tttgcgaaca aaaaagaggc aatgctcctt
    20761 gtcatcactg tcgtgcttgc cagctgattg agcacaatga cttttcagat gtcaccatct
    20821 tagagcctgt cggtcagctt atcaagactg ataccgtcaa agaaatgatg acaaattttt
    20881 cgcagaccgg ctatgagggc aggcggcagg tttttatcat taaggattgt gataagatgc
    20941 atgtcaatgc agctaacagc attttaaaat atatagaaga gccacaaggg gattgctata
    21001 tgtttttact aacgaatgat gacaatcagg tcctaccaac gatcaagagc cgtacacagg
    21061 tttttcactt tccaaaagat gagcactacc tctctgagct ggcccaaaaa aaggggcttt
    21121 tgaaacatca agcagacctc ttagccagat tagcagccaa tgcccagcag cttaccgctt
    21181 tttctgaaaa caccaggctg ttggagctga tggcgcaggc tgagcgtttt gtttccatct
    21241 ggtttcagga taaggaacag gcttatctgg agcttaatcg cttggttcag ctagcagagg
    21301 aaaaagagga gcaggacatg gcactaactc ttttaacctt aatcttggcg aaggactaca
    21361 gtcgacaaaa tgcttttacc tatctggagg ctgtttatca ggctagactt atgtggcaaa
    21421 gcaatgtcag ctttcaaaat acgttagaat atatggtgat ttcatgataa gtacgattgg
    21481 aattaaatat tgtgacacct gctctgtcag gtacgttcaa accgatcagg cctttcctgt
    21541 gcaaaccaag cttgtcatat ctgatggcaa gggcagtcga ttggcagtgg tcaattctcc
    21601 gataaaaagc ttttgtaagg acgacctgcc aaaggatatg ccctctgttt tgagacctgc
    21661 caatgacatg gactacaagg cttaccagca aaaccttcag ctagcagccc agtcaaagca
    21721 aaaagtagca gagatgattg acagaaatgg cttagacatg accttggttg acattgtttt
    21781 ctcccttgag agacgttatg ttttgattac ctttaccgct caggagcgtg ttgattttcg
    21841 ccagctcctc aaggatttgg ctgcctattt caagacaagg attgagctgc gtcagattaa
    21901 tagtcgtgag gaggcaaggg tttatggagg gctgggtccc tgtggtcgcc cactatgctg
    21961 ttcaagcttt ttaggagagt ttcctccagt ctcaatcaaa atgctaaaac atcaagggct
    22021 gtccttgcat tcggcaaagt ctttgggctg ctgcggtcgc ttgctgtgct gcctacaata
    22081 tgaggacgat ttttatcaag aaagtaagaa aaaatttcct gattatggta ctatagtaag
    22141 aacagcgcag ggaccaggtg aggttgcagg aattgatctt tttacagata ccattcaggt
    22201 tcgctttaag gaccagctgg ccttggtaac ctatgcttta gaggaggtta aagttagtga
    22261 ataaaaaaga actgtttgac gcttttgatg gcttttcaca aaacctgatg gtgactttag
    22321 ctgaaattga agcaatgaaa aagcaggtcc aaggactcgt agaggaaaat actatcctta
    22381 ggcttgaaaa caccaaatta cgtgagcgct tgagtcaatt ggagcacgaa aatctggcca
    22441 agacctcttc taagcagggc aaggaccact tggagggcat ttatgatgag ggctttcata
    22501 tctgcaattt tttctatggg caacgtcgtg aaaatgatga agagtgtatg ttttgtcgag
    22561 agctattaga tagaaagtag agtcatgcaa atccaaaaga gcttcaagga agaaaaagag
    22621 tcaggggttc tctatctggt gcctacccct attggtaacc tagaggatat gacctttaga
    22681 gcggtcaatg ttctaaaaga ggtggatatt atctgtgcag aggatacgag aaatactggt
    22741 ctgttgctca agcattttgg gataaagaca aagcaggtaa gctttcatga gcataatgct
    22801 tatgataaaa ttccagattt gctggacctg ttgttggctg gaaggtcatt ggctcaggtc
    22861 tccgatgctg gtatgccctc tatttcagat cctggtcatg agctagtcag agcagctatt
    22921 gatcgagata ttactgttgt tgctttgccg ggtgcttctg cgggcattac cggcctcatt
    22981 gctagtggct tggcgcccca gccccatctg ttttatggct ttttgccaag aaaagctggg
    23041 cagcaaaggg catttttgat gactaaggca gattatccag agactcaaat cttttatgaa
    23101 tctccttatc gtgttaagga tacgctaaca aacctgctgg cctgctatgg ggatcgccag
    23161 gtggtgctgg tgagagagtt aaccaagctt tttgaggaat accagcgtgg tcagatttca
    23221 gaggtcttga cctatctagc agaccatcca ctcaagggtg agtgtctatt gattgtggca
    23281 ggtgccaatc aagctgacgc atcagagcct gctgaggatt tggatctgct agcacttgtt
    23341 caacaggcta ttgctgctgg catgaagcct aatcaggcga tcaagacaat cgccaaagac
    23401 tataaggtga atcgccaaga gctctatcag caatttcatg ggcttggcta gactggcttt
    23461 taatccggac tagtcgcctg attgagagaa tctctagtag gccaagcaaa ggagaggtac
    23521 tcaagtaagg gctaatagct gtcttttgca cttctgagaa ttgtcattaa tgtaagcaga
    23581 tagatttgtc tgcacactaa gagagctagt cagttctctt tttttggctt cttgtcaact
    23641 ttaggggggt gactgataac tagtacctag tgaggaccag actggtgctt tttttgtgtt
    23701 gttaatagca atgagaagct tgcttttaat gtttttaagg ttcctaaagc cacaggcttg
    23761 tcgcttcacg ccttccctta atggtcactt tgcagtctta aacgaaaaaa atgctcccat
    23821 ttaggacgtt tcaacgactg tttaggatat ggaggaatgt tttacaaaaa aagcgttata
    23881 ctaaatatgt caaggttgca actggacaac atcgattttt agggagtatt tgcaatcaat
    23941 acaataattt gacgtaatgg ctacagaaat gcttgctagc tttgaaggag gaaaaaataa
    24001 ttgggctgcc aatgtgtcag gtgtgattgg agcaggaagt gcaggcgcag cacttggatt
    24061 tccagtatgt ggagtagctt gtggatctat tggtgtcaca ggaggctttt agaaatgaga
    24121 aaaacagaaa gattctgagt ttggaacctt gttttaggag gataatagaa atggaacatt
    24181 atagagcatt agcaataagt gaaatgcaag atatttcagg aggaaatgca gcaggtaatg
    24241 ctgttatcgg gggattagga ggtctcaaga caggaattac attttgcaaa atacctcatc
    24301 cggtgctaaa aggagtatgt atagacggct ttactgcttt aggagcatgc ttggcatata
    24361 aggtaaatta gatgttattg attacttttt caggtcttta tgctttaatt tttatctata
    24421 tactggttga cagtgctaag aggggcaaag aaggggcttc ttactttatt tttttaattt
    24481 tttat
//
LOCUS       DARYXS010000022        24452 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.022, whole genome shotgun sequence.
ACCESSION   DARYXS010000022 DARYXS010000000
VERSION     DARYXS010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24452
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.022"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            28..930
                     /locus_tag="TV193_000721"
     CDS             28..930
                     /locus_tag="TV193_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1512943.1"
                     /translation="MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQ
                     GIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPL
                     ILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
                     SFQIQESELCAFVSKNHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDIN
                     PQIILESASWDFLINSTRINPQLMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRL
                     KKDHYSTIEEYIFNKMLEKFHVIE"
     gene            complement(1827..2969)
                     /locus_tag="TV193_000722"
     CDS             complement(1827..2969)
                     /locus_tag="TV193_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512944.1"
                     /translation="MKALLPFELKKLIRTKSVLGMFIVSLLAIFGLFYINFFNGQISG
                     SSIDKIHGRDAVEINKRFAEEHTGQLSNELLIRTIKDYTLGGSSKNPVFNVYGYYVTS
                     HFDPKFRDYYFNLKKEETIDFSKITPKSQTALGSYLPFKELKLGNFAPWNQLFLVINS
                     AYILLLLLSVYFIAPVFSGDTAKNMNPILLTTRYGRNKLTIAKIISSYLISTSVFVTF
                     YAIILAVFVWYFGLSGWDTSVQLNLYWINSNVNIMAFPEKMTLLGTFINLVTYQFIGL
                     ILITAITILISSKVKSPLTGFALSAASVFVPSFLMDIFQAGIPHKVLSILSVSTASTP
                     NIMLKLAYDGFFGSFWVDGLVIVMIRLAFAFLCLYLAYLSIKRVSQ"
     gene            complement(2966..3829)
                     /locus_tag="TV193_000723"
     CDS             complement(2966..3829)
                     /locus_tag="TV193_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512945.1"
                     /translation="MLLELNQLSKSYGSKNILRRITTQFTPGLYGLLGANGTGKTTLL
                     NLISHFTTPDEGEILLDHKPQSEEFYQHIGFLPQQFSYYGRFSGRDFLLYMAALKGIP
                     KHKAKQETDELLKLVDLYDVRLKRIASYSGGMKQRLGIAQALLNDPKILILDEPTVGL
                     DPKERVKFRNIISELSANKIIILSTHIVSDVEAIAKEIIILKNGQFIHKSSSQELLKT
                     IFGKVWEFSVSDGSPLPRHGQYAVVNEKLVSSSRVFRVVSDEKPNQLAQLVSPTLEDL
                     YIYHFREEQVL"
     gene            complement(3840..4166)
                     /locus_tag="TV193_000724"
     CDS             complement(3840..4166)
                     /locus_tag="TV193_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HEL1512946.1"
                     /translation="MKYVILYKNRSVVKLPISETYDVTTHSSKPHTVVFVTLKGEFGA
                     ATSLRQIEGESAGKLKRCHRQYFINESKISGFDYATRIIKVTDSRISYRRSLLSTELQ
                     VLSRLI"
     gene            complement(4770..4934)
                     /locus_tag="TV193_000725"
     CDS             complement(4770..4934)
                     /locus_tag="TV193_000725"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512947.1"
                     /translation="MDSMTVDAEKASQLDLGIENAGWFHFKLTTAIKLKQVEKVFLFT
                     AIFNRVDEFI"
     gene            complement(5173..6069)
                     /gene="era"
                     /locus_tag="TV193_000726"
     CDS             complement(5173..6069)
                     /gene="era"
                     /locus_tag="TV193_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEL1512948.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAVMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGAFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETL
                     VQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKR
                     DEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNQKEY"
     gene            complement(6205..6606)
                     /locus_tag="TV193_000727"
     CDS             complement(6205..6606)
                     /locus_tag="TV193_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL1512949.1"
                     /translation="MASQDNNKRKWKNRTVIASLEFALTGVLTAFKEERNLRSHLLSA
                     LLASLAGIVFGISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKHAKD
                     MAAGAVLVISGYAVLTGLIIFVPKIWRMLCH"
     gene            complement(6587..7084)
                     /gene="ybeY"
                     /locus_tag="TV193_000728"
     CDS             complement(6587..7084)
                     /gene="ybeY"
                     /locus_tag="TV193_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEL1512950.1"
                     /translation="MYIEMIDETKQVSQEMMEQTIDLLNFAAKTIGKEDKEMAVTFVT
                     NDRSHALNLEYRDTDRPTDVISLEYKPELPIAFSQEDLELDPDLAGMIQEFDAYIGEL
                     FISVDKAHEQAEAYGHSFEREMGFLAVHGFLHINGYDHYTPEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            complement(7433..8059)
                     /locus_tag="TV193_000729"
     CDS             complement(7433..8059)
                     /locus_tag="TV193_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1512951.1"
                     /translation="MASFFEKLAEHRYLETERLCLRPVTLDDAKAMFDYASDEETVRY
                     SFPANQTIEETRQVIASVYLASPLGRWGIVLKETGDFIGTLDLHHIQLDLGRAEIGYC
                     LHKHHWGRGYATEAVKAVLVLCFEALGMNCVIAKHDKANPALGRVMAKSGMCFSHEEP
                     YAKRDHLDSNRFVTVLHYYLTKEDYDKQKSLASANKPDRYLHNSFESS"
     gene            complement(8114..8689)
                     /locus_tag="TV193_000730"
     CDS             complement(8114..8689)
                     /locus_tag="TV193_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEL1512952.1"
                     /translation="MTELLQAIMADPANRDYTKKGIEPLYAAPQTARIVIVGQVPGIV
                     AQETRLYWNDRSGVRLRAWLGVDDRTFYQSGLFGVLPMDFYYPGKGKSGDLPPRKGFA
                     AKWHGPLMALMPQVELVVLVGQYAQQYYLGEGCRRNLTETVQHFEDYLPDYFPLVHPS
                     PRNQLWLAKNAWFEEELVPVLKDKVRQILRG"
     gene            complement(8736..9836)
                     /locus_tag="TV193_000731"
     CDS             complement(8736..9836)
                     /locus_tag="TV193_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEL1512953.1"
                     /translation="MHYSTDISLNHPDDLLALFGSNERHLKMIESHLNVVIHARTERV
                     QIIGDDERAVELARLTIQALLVLVGRGMVINTSDVVTALSMADSDRLDQFVALYEEEI
                     IKDFYSKPIRVKTLGQKAYVDSIKHHDVVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTTRLMERDIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFQSKMIVNGDISQIDLPRHITSG
                     LIDAAQKLQAIKQIDFVHFSAKDVVRHPVVAEIIKAYETVGSKAESLKSSPNQLQHQT
                     KAPDRPKTETGQSTSGLTTYEVIGELPKEDKS"
     gene            complement(9939..10154)
                     /locus_tag="TV193_000732"
     CDS             complement(9939..10154)
                     /locus_tag="TV193_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEL1512954.1"
                     /translation="MRKAFYTWLMAQRNSTSNKPAALLADLVFEDPTFPKHTDDFETI
                     SRYLEEEASFSFNLGQFDQIWEDYLSH"
     gene            complement(10151..10660)
                     /gene="msrA"
                     /locus_tag="TV193_000733"
     CDS             complement(10151..10660)
                     /gene="msrA"
                     /locus_tag="TV193_000733"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEL1512955.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHVHNPSYEQV
                     CSKTTGHTEAVEIIFDPSLISYSDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTDE
                     RQREIAERSKQTLQASGRFDQPIVTSIEPAEPFYLAEDYHQGFYQKNPERYAQSSAIR
                     HQFLEEHWQ"
     gene            complement(10998..11855)
                     /gene="cvfB"
                     /locus_tag="TV193_000734"
     CDS             complement(10998..11855)
                     /gene="cvfB"
                     /locus_tag="TV193_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEL1512956.1"
                     /translation="MNHLLATVITGLVKEENSQFYLVQKEGLSFALAKEEGSHRLGDM
                     VKGFVYTDMKQRLRLTTKPIDARRDHYGWGEVTTVRRDLGVFVDTGIPDKEIVVSLDV
                     LPELKDLWPKKGDRLYLKLVVDKKDRIWGLPAEPEIFQRLASPAYDNMQNQSLPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYTEPRLGQVLTARVIGFRERDRTLNLSLKPRSF
                     EMLENDAQMILTYLKSNGGYMTLNDKSSPEDIKATFGISKGQFKKALGGLMKANKIKQ
                     DVTGTELIS"
     gene            complement(11989..12546)
                     /gene="frr"
                     /locus_tag="TV193_000735"
     CDS             complement(11989..12546)
                     /gene="frr"
                     /locus_tag="TV193_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEL1512957.1"
                     /translation="MANAIIETAKERFTQSHHSLAREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGETAKVSIRNIRRDAMDEAKKQEKAKEITEDELKALEKDI
                     QKATDEAVKEIDRMTADKEKELLSV"
     gene            complement(12583..13311)
                     /locus_tag="TV193_000736"
     CDS             complement(12583..13311)
                     /locus_tag="TV193_000736"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEL1512958.1"
                     /translation="MKPKYQRILIKLSGEALAGDKGVGIDITTVQSIAKEIAEVHNSG
                     VEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKGRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPRKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIKRVVFGEHIGTTVSNKACD"
     gene            complement(13610..14290)
                     /locus_tag="TV193_000737"
     CDS             complement(13610..14290)
                     /locus_tag="TV193_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512959.1"
                     /translation="MIEFRHVYKSFHQKPVLTDCHFQMEKGESLGIMGESGSGKTTLA
                     RLIIGLEQPTAGQVLFHGQPYSVKVCGPRILLVFQDALRSVNPLFTIQEILTEALSKD
                     FALEEVVQILAAVGLDATHLGKKARELSGGQLQRVCIARALLLRPEVIIFDEALSGLD
                     PITQGQLLDLLYELKQEYQLTYIFIAHDANICQAICHRVLLLEQGRLVAVRDKEPQTS
                     CGGIGLDN"
     gene            complement(14277..15065)
                     /locus_tag="TV193_000738"
     CDS             complement(14277..15065)
                     /locus_tag="TV193_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1512960.1"
                     /translation="MERLIVNDLSAYNGSDVLLSKLNLELPLGSSLVIVGRSGSGKTL
                     LTKLLIGQCPSNVQMTGRITCQDMRLDQLDAKQWQSIRGRHMAYMVQNPMAMFNPFQT
                     IEAHLLETIRSHERLSKRACLKRALPFMRELYLEQPEELLRKYPFELSGGMLQRVMLA
                     ILLCLDPQIIILDEPTSALDDANRSNIIRMLKLLQDKGKTIITVTHDYQLAQTLGGQL
                     LVMSKGKIIEQGSVESIFHRPSQAATKELLLQNHYDRLIRYDRV"
     gene            complement(15053..15859)
                     /locus_tag="TV193_000739"
     CDS             complement(15053..15859)
                     /locus_tag="TV193_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1512961.1"
                     /translation="MPKYVIGSAVMLLLLFICVLFAPYLAPFDPHAVDVASKLMPPSQ
                     QHLLGTDQLGRDVLSRLLYGAKYSLLLAVTISLLELSIGAVVGLVVGWYQGRLEAAFL
                     WLADVVSAFPSFLLSLATMGILGQGIGNMILAIVLVEWLYYARLMVTMVKSAKAEPYV
                     ISAQTMGLSVRHILKKHILPFVYRPIVVLALMNIGNIILMISSFSFLGIGVQPNVTEW
                     GMMLHDARSYFRTALWLMMSPGLAILVTVLAFNSLGDYADAKGWRKTWNG"
     gene            complement(15844..16785)
                     /locus_tag="TV193_000740"
     CDS             complement(15844..16785)
                     /locus_tag="TV193_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1512962.1"
                     /translation="MMKKLISTFGALLMISIVTFVLVKLSSANPAEQYLRLSKISITP
                     EALHNARLYLGLDKPLWEQYVTWLSDILVGNFGTSYVLKVPVLPLVVERFLATLMLSL
                     TSFLLVLVIAFPLGVGSGLFEHSLFDRLVRLFSFVAVSMPSFWLGYLLIIAFSVKLNL
                     LPVSGKAGASSLILPSITLSFSLIGQYTALIRKAISEQLTSLHVENARLRGVKTYYIV
                     KHHLIRNAFPAIATGLSLTFVYLMTGSIIVEDIFSWNGIGSLFVMSLKAADIPVIQAC
                     MLLFGALFLLHHVITQELVSFIDPRLRKTKEEACPNT"
     gene            complement(16863..18485)
                     /gene="nikA"
                     /locus_tag="TV193_000741"
     CDS             complement(16863..18485)
                     /gene="nikA"
                     /locus_tag="TV193_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HEL1512963.1"
                     /translation="MKTKLNVLLLFFFALLLTACQNAKQASYRTDQLRIAWGEDFGDV
                     NPHRYNPDQFVIQDMVYEGLVRYGDKGNIEPALAESWTISPDGKTYTFNLRQAKFSDG
                     SDFNAQNVKRNFDSIFSEQNKGNHNWFHFTNQLDSYKALDDHTFEIKLKEAYSATLYD
                     LSMIRPIRFLADAGFPDGDDTNKHNVKKPIGTGQWVVKEKKANEYITFTRHESYWGEK
                     PKLKEVTIKIMPDAETRALAFEAGDIDLIYGNGLISLDTFVQYAKDKKYVTDVSQPMS
                     TRLLLLNAKQSVFQDKRVRQAMNHAVDKKAIAKHTFRGTETAADTIFSKTTPHADAGL
                     VPYEYNLQKAKDMLTAAGWKENQEGIREKDGQQLRLQVPYISTKATDKDLVEYFQGEW
                     KKLGIDVVLTAMEEDDYWANAKTGQFDMMLTYSWGAPWDPHAWMTALTAKADHGHPEN
                     IALESLPSKAEIDRLIKSVLIEPDGDKVDKGYKQVLSLLHDEAVYIPLTYQSVVSVYR
                     KGDFKTMRFAPEENALPLRYIEKSAADKAVKN"
     gene            18987..20627
                     /locus_tag="TV193_000742"
     CDS             18987..20627
                     /locus_tag="TV193_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1512964.1"
                     /translation="MKKTMKKMLAASTLCIIMSGSFISGSARVLAEEYYGWNDVTGSK
                     SPFPLYVTPKNGDKNIKVQQTVVYCFNRDGQWPENWEKRIYESPDKVPHKLPEYNKKS
                     GSDNLFQLLNPKIKIKNPMAALLAVLEDGYPTSSSSGVNQRTTQLAIWHFTDGLSNLA
                     QFHLTPEETSAYNKLIEKGTNASNQSENKLLNKTLDIYSYIDGTGDKKHNYQHLLGST
                     PIPIDNSKENKCQCTKVDLMRTGDGVKIIVYVDNNGNNRYDNGDKMLKEETIKHGQRG
                     PAGESGKPGPKGDRGETGARGPAGPQGKPGKQGPRGDKGETGERGPQGEKGEPGTPGP
                     KGEDGKDGAPGRDGQPGPKGEKGDPGKDGQDGKPGEKGEPGIPGPKGEDGKDGAPGRD
                     GQPGPKGEKGDPGKDGQDGKPGEKGDPGRDGKDGEKGERGEQGPKGERGEQGPQGERG
                     EQGPRGENHTPTPDPMPEPAPKPESKPEPKPTPQPEVKPLPETKPQKPTKPSAMASQP
                     SSKALPKTNDTSGLMTVLGTGLLSLLGLGFLAKRKRKQ"
     gene            complement(20871..21560)
                     /gene="rplA"
                     /locus_tag="TV193_000743"
     CDS             complement(20871..21560)
                     /gene="rplA"
                     /locus_tag="TV193_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEL1512965.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQAIIGKVSFDADKLVENFKAFHEVMVKAKPATAKGTYMTNVSITTTQ
                     GVGIKVDPSSF"
     gene            complement(21666..22091)
                     /gene="rplK"
                     /locus_tag="TV193_000744"
     CDS             complement(21666..22091)
                     /gene="rplK"
                     /locus_tag="TV193_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEL1512966.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            22327..23124
                     /locus_tag="TV193_000745"
     CDS             22327..23124
                     /locus_tag="TV193_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1512967.1"
                     /translation="MHKKVTIKDVAREAGVSVATVSYVINNREDQKISPETRNKVLQM
                     INLLNYRPNQAAKSLVTQKRQLIALYYKEHSSVLKRAEQLHFITQLSAFLYTKHYHLI
                     CLNQEYIGKYDVADVILTLEVTKEEFYKIGNSNFVPLIAIDSIIDDPLFFQINSDPHL
                     LFNKASAYFAGEPFELVSLPIQNQEITQGLAQQFDNICWIHSICDIESVSKGNILVID
                     DTVNHILSKHKNKLYLPSISEAKLLKLFQAIEWASKREAINNHNILV"
     gene            23279..23629
                     /locus_tag="TV193_000746"
     CDS             23279..23629
                     /locus_tag="TV193_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEL1512968.1"
                     /translation="MIIYKLTALAFIILTPLFSMIMISLLRLGRRGLKFPDLALPLFV
                     FEIVIVSGKFFTHHLLPYYLIVMSLLAIVMALLLIIRIQQFSYRRFFKLFWRVGFLVT
                     LLFYLMLVGLIFIV"
     gene            complement(23958..24422)
                     /locus_tag="TV193_000747"
     CDS             complement(23958..24422)
                     /locus_tag="TV193_000747"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1512969.1"
                     /translation="MTILTISDQKVNASQYRWRQYYYRMSPTERELKKEKEVLRNFIA
                     TIKLSYSEANEMEAKVYGADSFSKLRAIKEELQSLKSRYFKISNKVEIVSSLIDEHFP
                     EGHSRNIMKKYRLEFLDRLMGIQYDVGLNKDRALDDLSERIIMTRKKLWYIQ"
BASE COUNT         7630 a         5628 c         4326 g         6868 t
ORIGIN      
        1 gacatctgaa atgaaagaag aggcaatatg gatattaaac atttacgctt tttcattgct
       61 attgtagaaa ataattttaa cctgagccgt accgctcaac agctttatat ttcccagcct
      121 accctcagta ttatgattaa tgattttgaa gaaaagcagg gcattaagct cttcaataaa
      181 aaatacaata aaatcctcgg cttaaccatg acaggcaagc aattttatga ggattctttg
      241 gaggttatcc gcaaatatga caagatgcac caaaatctct tttccaccaa tcaaaagttg
      301 gacggtaata tcactatcgg cattcctcca ttaattctgt caattgtttt ttcaaaaatc
      361 atgccagaaa ttattctaga aaatcccaat atccacttta atattaagga gtatggtgct
      421 aatcggctac gtcaggaatt gattttagag aatgtggata tcgccattct tctgcatcct
      481 gaacgaattg ctgcaaacac cattgattct ttccaaatcc aagaatctga gctctgtgca
      541 tttgtctcca agaaccacca tttggccaat aaaaaaatcc tgacttggat agaactccac
      601 aatgaaaaac tagctatatt tgataaaacc ttcatgattc accatctcat caaggaaaaa
      661 tgtaagtata ctgacattaa cccccaaatc attctggaat cagcttcttg ggactttctg
      721 atcaattcta ctcgtatcaa ccctcaacta atgacgatta ttccaaaacc aacggtagat
      781 agctatggtt ttcaggatat tgtggctatt cctatggaga atcctattcc ttggaaagtc
      841 atggttagtc gtctcaaaaa agatcattat tccaccatag aagaatacat tttcaacaaa
      901 atgcttgaaa aatttcatgt aatcgaatag agactaacaa gtgatccctt tcacatgact
      961 gcacgtgccc ttcgacatat ggcacctcaa ctaaccctta gcgcatatgg aaacagctca
     1021 attctttttg aaggataaaa ctaaagaggc ttgacgatcc atactaactc agacccaata
     1081 ttattatcaa gatcctaaat attaacacaa ctcatttata acaattaact tacaaaaaat
     1141 ggtctactcc tttgaggcgt gacagcaata ctgcaattta taaaaaatga ctgtcaagac
     1201 aatatctctg aactcagtca ctgtttctca aaaatcactc acatctaatg gagtactatc
     1261 aagaaaaagt tatttttaaa atcatcaata acctatctaa attttctaaa caatgccata
     1321 taaaaagagc tggagtcacc aagctctaat tgatttttac atgatgctct ataacaatat
     1381 cgtttaaaga tcattctttt ttactagtat gttgatcaca ttttctaaaa gccagaaaga
     1441 gacttgaata ccgagtccct tttcttttta tctataaaca gccttaaaga agcccagaca
     1501 ggctgcggta attttcttaa catgagcttc tactatttct cttgttaagc cctgctcact
     1561 tgatgattcg ttatttttac cacctgaaga ctctcctcta cataggctac tttgtcatct
     1621 agttcctgct tcttaacgat atatcatcgt ctcaattgat gccacttccc ttatcatctt
     1681 agaaaaaagc taatttctat acctttaggt gttctagatc acaaaatagc tttctcaatc
     1741 ctatctacct tgcaagaatt cattgaatgc ccttaacttt tgcagtaacg acaataaaaa
     1801 tagtttagat aacgatgcta ttgatgttac tgacttaccc tctttattga taagtatgct
     1861 aaatataagc aaagaaatgc aaaagctaat ctaatcatga caataactaa tccatcaacc
     1921 caaaaactgc caaaaaagcc gtcataagca agcttaagca ttatgtttgg tgtactcgca
     1981 gttgatacag ataaaatact caacacctta tgaggtattc ctgcttggaa aatatccata
     2041 agaaaacttg gtacaaaaac actagccgca gacaaggcaa aacctgtcaa tggagactta
     2101 accttacttg aaataaggat agtgatagcc gtaatcagga taagcccaat aaactgatag
     2161 gtgactagat tgataaatgt tcccaaaaga gtcatttttt ctggaaaagc cattatattc
     2221 acattgctgt taatccaata cagattgagt tgaacactcg tgtcccaacc acttaatcca
     2281 aaataccaaa caaagaccgc taatattatg gcgtaaaaag taacaaacac tgaggtgctt
     2341 atcaagtaac tacttattat cttggctatc gtaagtttat tacgaccata cctagttgtc
     2401 aataaaatag gattcatatt tttagcagta tcaccggaaa aaacaggagc gatgaagtaa
     2461 acagacaaaa gaagaagaag gatataagca ctatttatga ccagaaaaag ctgattccag
     2521 ggtgcaaaat tacccaactt cagctcttta aagggaagat aagagccaag agccgtttga
     2581 gattttgggg tgatcttact gaaatcaata gtctcttctt ttttcaaatt aaaataataa
     2641 tctctaaatt ttggatcaaa atggctagtt acatagtagc catacacatt gaagacagga
     2701 ttttttgagc tgccacctag agtataatct ttgattgttc taattaataa ctcattggac
     2761 aattgaccgg tatgttcttc cgcaaatcgc ttgtttatct caacagcatc tcttccatga
     2821 attttatcta tcgaagaacc actgatttgt ccattaaaaa agttgatata aaataaccca
     2881 aagattgcta ataagctaac aataaacatt cccaaaactg atttggttcg gatcagtttt
     2941 tttaattcaa atggtaagag agctttcata acacctgttc ctctctaaag tgataaatgt
     3001 ataagtcttc taaggttggt gacactagtt gagccaactg atttggtttc tcatcactaa
     3061 ccacacgaaa aacacgacta gatgaaacta gtttctcatt gactacagca tactgaccat
     3121 gccttggtaa cggcgaacca tcagagacag aaaactccca gaccttgcca aagatggttt
     3181 tcaacaattc ttgactacta ctcttatgga taaattgacc attttttaaa atgataatct
     3241 ccttagcaat agcctcaaca tcagagacaa tatgagttga taagataata attttgttgg
     3301 ccgacaattc gctaataata ttgcgaaact tcaccctttc ttttgggtct aatccaactg
     3361 tcggctcatc taaaatcaag attttagggt cattgagtaa ggcctgggca ataccgagac
     3421 gttgcttcat accaccagaa taagaggcaa tccgcttcag acggacatca tatagatcca
     3481 caagttttaa caattcatcc gtttcttgct tggctttatg tttaggtatt ccttttaagg
     3541 ctgccatata aagaagaaag tctcgaccag aaaaacgacc ataataacta aactgttgag
     3601 gcaaaaaacc aatatgctga taaaattcct ctgattgagg tttgtgatcc agtaaaatct
     3661 ctccttcatc aggagtcgta aaatgactaa tgagattgag caaggtcgtt ttccccgtcc
     3721 cattagcccc taaaagtccg taaaggcctg gggtgaattg agtagtaatc cttcgcaaaa
     3781 tatttttcga tccgtagctc ttactcaatt gatttaattc taataacata gaaccctcct
     3841 taaatgagtc tactgagcac ctgtaactca gtactcagta gacttctcct gtacgaaatc
     3901 ctgctgtctg taacctttat tattctcgta gcataatcaa atccagagat tttcgattca
     3961 ttaatgaaat attgacgatg acaccttttt aatttcccag cactttctcc ctcaatctgt
     4021 ctcagtgacg tagctgcccc aaattcccct tttagggtaa caaatactac tgtgtgaggc
     4081 ttagatgaat gtgttgtcac atcataggtt tcagagattg gtaatttaac aactgaccta
     4141 ttcttatata aaataacata tttcattgac gtcctccttc tctatttata tcttaataca
     4201 agtacaagca ttgagacggt aaagtctcaa atggtatcta tcatatcctg aatggtatca
     4261 cagtagctgt ttaagatgtc atagaggcat ttgagaaatg taacctgttt tcctttcgtt
     4321 ttttgatcat atgatattgt attagttcgg agaaccatgg taatcattca aatcttacat
     4381 aaacctctct tgggatatgg tattagcgtc tatattaatt actacttcaa cagacacctt
     4441 tttaaagctg ctaaaattgt cagtggcaaa caaataggct ataggtataa atctcacact
     4501 tattttatca taaaatcatt ctttttatca tctaatcaaa tgtacaagca ctttaaagtt
     4561 attctcatga ctctattatt cttattggaa gccatattaa ttacgacgac attttcagaa
     4621 atcattatcg tgtgtttggt atcatcgaca caaccgctaa taaatcgttt aaatgtatcc
     4681 aaaaccaaat tcatgattac ctgttcaaag aataaccaga gggcttactg attgctttaa
     4741 caaatatttc tagtcttctc attttgtact catataaact catctactct attaaaaatt
     4801 gctgtgaaca gaaaaacctt ctcaacctgt ttcagtttta tagccgtagt tagtttaaag
     4861 tgaaaccacc ctgcattttc tatacctaaa tccaattgac ttgctttttc agcatcaaca
     4921 gtcatgctat ccataagata acacaccacg atgtgttgtg attattgttc ttctatattt
     4981 agccttacct cctgaaaaca aaaaaagaga acacctttta aatgttctca tataagcaat
     5041 cttatatatt aaatgaggat tcgatctaat gacaagacag ccttattgct accaataatg
     5101 cagcttacca aacaagggca atcagtataa gggttgctaa ccagctctgc tgacatagcc
     5161 tgctttgagc gatcaatact ccttctgatt atagccaaag tcagctaaat caagcttttt
     5221 gtcacgccag tttttcttaa ccttgaccca ggtctccaga tagaccttat cgcctagcat
     5281 tagctcaata tcacgccttg ccagcttacc gatttttttg agcatggcgc cttgttttcc
     5341 aataataatg cctttttggc tgtcacgctc taccatgatg gtaactcgga tatgcacctt
     5401 gtcagtcacc tcatcacgct tcatcgaatc gaccacaaca gcaactgaat gaggcacctc
     5461 ctgctgtgtc aagtgaagca ccttttcacg aaccatctca gaaacaagaa agcgctctgg
     5521 gtgatcagtg atttgatcct ctgggaaata ctggaagccc tcttcaaggt tatcctttaa
     5581 gagctgaacg agcgtttcga cgttgtttcc ttgaagtgct gaaataggaa caatttcctt
     5641 aaagtccatc tgactacgga aatcatcaat ctgctccaat aattggtctg ggtgaacctt
     5701 gtcaattttg ttgatcacca aaataaccgg aatacgagca gccttgaggc gttcgataat
     5761 catatcatca cccttaccac gcttttcatc agcaggcacc ataaaaagaa ccgtctcaac
     5821 ctcacgcagg gtactatagg ctgattccac cataaaagca cctaaggctg tcttaggctt
     5881 atgaatgcct ggcgtgtcaa taaaaacaat ttgctctgtc tctgtggtat agattcccat
     5941 aattttatta cgggttgtct gcgccttatc gctcataacg gcgatttttt gtcccatgac
     6001 atgattcaaa aacgttgatt tgccgacatt tggtcggcca agaatggcaa caaagcctga
     6061 tttaaacata agctactaag ggcctaaagg atcagtcaag gtaagaatca agcagcaggc
     6121 tattcacctg attgctttcc taaagcttat actcctttcc tgcgctgcac tatcgcacag
     6181 gatagcccat ttcctttcat ttttttaatg gcataacatt cgccaaattt tgggaacaaa
     6241 gataatcagc cccgtcaaaa cagcatagcc tgaaatgacc aggacagcac ctgcagccat
     6301 atccttggca tgcttagcca gcatggagaa atggtaatca cttgccaagt caaccacatt
     6361 ttcaatagct gaattgacaa tctctaaggt aatcaccaaa aaaatagcca gcaataaaaa
     6421 cagccattct atagcagaaa taccaaaaac aatcccagcc aaagaggcta acagggctga
     6481 caaaagatga cttcttaggt tacgctcctc cttaaaggct gtcagaaccc ctgtcaaagc
     6541 aaattctaag ctggcaatta ctgttctgtt tttccatttg cgtttattat tgtcttgtga
     6601 ggccataagc agtcaaaatc tcttcctgta acgtaaacat ctctttttct tcctcaggag
     6661 tgtaatgatc ataaccatta atatgcaaaa aaccatgaac agccaagaag cccatctcac
     6721 gctcaaagga atgcccatag gcttctgcct gctcatgggc tttgtcaaca gaaataaaca
     6781 gctccccaat ataagcatca aactcctgta tcatacctgc caagtcagga tcaagctcca
     6841 aatcctcttg gctaaaggcg atcggaagct ctggcttgta ctccagagaa atcacatcag
     6901 tcggacgatc agtatcacga tattcaagat tcaaggcgtg gcttctatca ttggtcacaa
     6961 aggtaaccgc catttccttg tcctctttac caattgtttt ggcagcaaaa ttgagcaaat
     7021 caatggtttg ctccatcatc tcttgagaaa cctgcttagt ttcatcaatc atctctatat
     7081 acatcattat atgaagaggt cctagcaaga caggtccaaa caaacaccac actgctaggt
     7141 caaaaagctt gatacctctt atcctttcaa catcatttca gtactttctt tccattatac
     7201 cacaagaaaa aagaaaaagc aggcattagt ctagcctgct ccaaaagaag ccggaataat
     7261 gacaagatcg ttgatacccc agcagctgct gtttctggaa tacccagagc ctgctgcgca
     7321 gaatacagtc ctcttagata gctgggactc ctaggattac aatagtagat aagcctttag
     7381 accacttcca tcgcctaaaa actaatccta aacggctttc ccttagatac cactagctgc
     7441 tctcaaagct attgtggagg taacgatctg gcttattggc tgacgccagt gatttctgct
     7501 tgtcataatc ttctttggtt aaataatagt gcagcactgt cacaaaacgg ttggaatcaa
     7561 ggtgatcacg cttagcatat ggctcttcat gtgaaaagca catgccgctt ttagccataa
     7621 cacgtcccaa agccggattg gctttatcat gcttagcaat cacacaattc atgcctaaag
     7681 cttcaaaaca caagaccagt acagccttga cagcctctgt cgcatagcct cttccccagt
     7741 gatgcttatg aagacaatag ccaatctcag ctctacctaa atccagctgt atatgatgaa
     7801 gatcaagcgt cccaataaag tctcctgttt cctttaacac aatcccccac cgtccaagtg
     7861 gactagccag atagacagaa gcaatgactt gacgggtctc ctcaattgtc tgattggctg
     7921 gaaagctata cctgacagtc tcttcatcag aagcataatc aaacatggct ttggcatcat
     7981 ccaaggtcac tggacgcagg catagacgct ctgtctcaag atacctatgc tctgctagtt
     8041 tttcaaaaaa gcttgccact actactctcc ctttcctaaa aatctaactc acctaacagc
     8101 atgactgcct gccctagccg cgtaaaatct gcctcacctt atcctttaaa acaggaacca
     8161 gctcctcttc aaaccaagca tttttagcca accaaagctg atttctagga gatgggtgaa
     8221 caaggggaaa ataatccgga agatagtcct caaaatgctg caccgtttcg gtaagattgc
     8281 gtctacaacc ttcaccaagg taatattgct gggcatactg tccgaccagc accaccaatt
     8341 caacctgagg catcaaggcc attaacggac catgccactt ggcagcaaag ccctttcgcg
     8401 gtggtaaatc acctgatttt cccttaccgg gataataaaa atccatagga agaacgccaa
     8461 acaagcccga ctgataaaag gtcctgtcat caacacccag ccaagctctc aagcgaactc
     8521 cgctacgatc attccagtac agacgcgtct cctgagctac aataccaggc acctgaccaa
     8581 caatgactat ccgagcggtc tgaggagctg cataaagtgg ttcgatacct tttttggtat
     8641 agtcacgatt ggcaggatca gccataatcg cttgcaatag ctctgtcatg ataccctcac
     8701 tttcataaaa ggctcttcag gtgaagagct cttttttacg atttgtcttc tttaggcagc
     8761 tctccaatga cctcataggt tgttaagcct gacgtagact gacccgtctc tgttttaggc
     8821 cgatctggag ccttagtctg atgttgcagc tgattagggc tgctttttaa tgactctgct
     8881 tttgaaccta cagtttcata ggccttaata atctcagcaa caacagggtg acgcaccacg
     8941 tccttggctg aaaaatgcac aaaatcaatc tgcttgatgg cctgcaattt ttgagctgca
     9001 tcaatcaagc ctgatgtgat atgacgcggc aaatcaatct gactaatgtc cccattaaca
     9061 atcattttag actgaaaacc aagtctggtt aaaaacatct tcatctgcat gatggtcgtg
     9121 ttttgcgcct catctaaaat cacaaaggca tcatctaagg tccgaccacg catataagcc
     9181 aagggagcaa tctcaataat atcacgctcc attaaccgag tagtctgctc tttaccaaga
     9241 atctgataaa gggcatcgta gactggtcta aggtaaggat caaccttttc cttcaaatcc
     9301 cctggtaaaa agcctaagct ttctcctgct tcaacagctg ggcgtgtgag aatgatccgc
     9361 ttaacctgac cacgctttaa agcagtaact gctagcgtaa ctgctaaaaa ggtctttcct
     9421 gttccagccg gaccaatacc aaataccaca tcatgatgct tgatactatc aacataggcc
     9481 ttttgcccta gcgtcttaac acgaattggc ttgctataaa agtccttgat aatctcttcc
     9541 tcataaagag caacaaattg atcaagccta tctgaatccg ccatagacag cgcagtcacc
     9601 acatcagagg tattgataac catgccacgc cccaccaaaa ctaaaagggc ttgtatcgtc
     9661 aaacgcgcta gctcaacagc ccgctcatca tcaccaataa tctgaactcg ctcagttcta
     9721 gcatgaatca caacattgag gtgagattct atcatcttca aatggcgctc attgctacca
     9781 aaaagagcta acagatcatc tgggtgattc aagctaatgt cagtcgaata atgcaaattt
     9841 gtcttccttt tccatctata agtaactcta ttataacaaa ttttgctata aatcgggaat
     9901 aagacccagc tttaaagcct aaaagagcta gcctatggct agtggctaag gtaatcctcc
     9961 caaatctggt caaactgccc cagattgaat gaaaagctcg cttcctcttc aaggtaacga
    10021 ctgatggtct caaaatcatc tgtatgcttt ggaaaggtcg ggtcctcaaa aaccaaatca
    10081 gctaataaag cagcaggctt attagatgtc gagttgcgct gagccatcag ccaagtgtaa
    10141 aacgcctttc tcattgccaa tgctcctcca aaaattgatg acgaatagca ctactttgtg
    10201 cataacgctc tggattcttt tgataaaagc cctgatgata gtcctctgct agataaaaag
    10261 gctctgccgg ttcaatgctt gtcacaatgg gctggtcaaa gcgccctgag gcctgcaggg
    10321 tctgcttgga ccgctctgca atttcccgct gccgctcatc agtatagtaa atcaccggcc
    10381 gatagttgtc tcctctatcc tcaaattgcc caaaggcatc ggtcgggtct gtctgagccc
    10441 agtaaagctc taccaaatct gaatagctga tcagactcgg atcaaagata atctcaacag
    10501 cttcagtatg gcctgtcgtc tttgagcaaa cctgctcata gcttggattg tgaacatgcc
    10561 ctcctgtgta gccacttctc actgataaaa tacctgcctg ctcctcaaaa ggctgcacca
    10621 tacaccaaaa acagcctcct gcaaaaattg ctctttccat acctaatctc cactttcttt
    10681 gtccttacat tagtgatttt cattgtaaca aaaaaccttg ccagaggcaa agcttaatat
    10741 aaaacaagtc acagactcaa agtaacaaga ctcctcagcc caactagtgc ctagcactaa
    10801 gcagtactgt caagcagcca ctactagatc aagagggcca cacagagctt tttcgacaac
    10861 aaaaatgatt ggcgctttaa aacaggctat cagctaagct ccacactcaa aataaggaag
    10921 ctagctatac tgataaagga taagtcttag caacaccgat ccagcttatg attataggct
    10981 aagagacaga cagctcccta tgatatcagc tcagttcctg tcacgtcctg cttgatcttg
    11041 ttagccttca tcaaaccacc taaggccttt ttaaattgac ccttggaaat cccaaaggtt
    11101 gccttgatat cctctgggct tgacttatca ttaagagtca tgtagccacc attagacttg
    11161 agataggtca gaatcatctg ggcatcgttt tccagcattt caaaggaacg cggctttagc
    11221 gaaaggttga gggtacggtc acgttctcta aagccaatca cccgagcggt caaaacctgc
    11281 cccaaacgag gctccgtata acgctcgcta gggtggataa agcccagcat attattttct
    11341 ggcaggtaaa caaaggtccc tgatagcttc aagcgataga caatagcagg caggctttga
    11401 ttttgcatgt tatcataggc tggactagca agcctttgaa atatctctgg ctcagctggc
    11461 aaaccccaga tacgatcttt tttgtcaacc acaagcttaa gataaagcct gtctcctttt
    11521 ttaggccaaa gatcctttag ctccggcaaa acatctaagg aaaccacaat ctccttatct
    11581 ggaataccag tatcaacaaa caccccaaga tcacgacgga cagtggtcac ctcgccccag
    11641 ccataatgat cacgccttgc gtcaataggc ttcgtggtca agcgtagtct ttgcttcata
    11701 tctgtataga caaagccctt aaccatatct cctaatctat gactgccttc ctccttagct
    11761 agagcaaagc tcagcccctc cttttggaca agataaaact gactattttc ttcttttact
    11821 aagccagtga taactgttgc taataaatga ttcatatctt tttgttcttt cttttaaaaa
    11881 atagggacaa gtccaaagca gctgcttttt agccttgtca cctatcctgt tatgcctgat
    11941 gtgtattagg ttacgcagct gatctagctt aatgatcaga taagccgctt aaactgaaag
    12001 taattccttt tctttgtcag cagtcattcg gtcaatctct ttgacagcct catctgttgc
    12061 tttttgaata tccttttcca aggcttttaa ctcatcttca gtgatttcct tagccttctc
    12121 ctgcttttta gcctcgtcca tagcatcacg acgaatattg cgaatcgaaa ccttcgcagt
    12181 ctcaccaacc tttttcactt ccttggctaa ttccttacgt gtttcttctg taagcgctgg
    12241 aataaccaag cggatgacag agccatcgtt agctggtgta atgcccaaat cagaagcatt
    12301 caaggcacgc tcaatatcct tgattgatga tttgtcaaat ggtgaaatca aaagcacacg
    12361 cgcctctggt actgtaatag aagccaattg gttcaacggc gttggtgcac cataataatc
    12421 cacctgaata cgatccaaaa ggctagcatt agcacgacct gcacgaatgc ttgcatactc
    12481 gcgtgctagt gagtgatgtg actgtgtaaa acgttctttc gcagtttcaa taattgcatt
    12541 tgccatgatt gtttttctcc ttaatccttt agctctaaaa tcctaatcgc aggccttatt
    12601 tgataccgtt gtgccaatat gctctccaaa gaccacacgc ttgatatttc ctgcttcatt
    12661 catattaaag acaaccaaat caatatcatt atccattgac aaggttgaag ctgtcgcgtc
    12721 cataatcttg agaccgcgct tgataacctc cccatgagtc aattcatcaa acttaacagc
    12781 gtttgcgtcc tttcttgggt cagcattgta gacaccatca acaccatttt tagccatcaa
    12841 gatagcatct gcctcaatct cagcagcacg taaggccgct gtcgtatctg ttgaaaaata
    12901 aggtgaccca ataccagcac cgaaaacaac aatgcgcccc ttttccagat gacgaagcgc
    12961 acgacctcga atataaggct ctgcaacgtt ttgcatggga atagctgtct gcacacgagt
    13021 atcaacgcca taatgctgaa ggctatcagc cattactaga gcattcataa cggttccaag
    13081 catgcctgtg taatcagcct gcacacgatc cataccagcc tctgcagcag gctcaccgcg
    13141 ccagagatta ccaccaccaa taacaagagc aatttcaaca cctgaattgt gaacttctgc
    13201 gatctcttta gcaatcgact gaaccgttgt tatgtcaatg ccaacaccct tatcaccagc
    13261 caaggcctcg ccagacaatt tgattaaaat acgttgatat ttaggtttca ctatttatga
    13321 tctccttatt ttgtccctac cattctacca caaaacaaaa aaatttaata gaccaatgca
    13381 agagaggaaa gcgaaatttt tgacgatcct tttatcaaga tccctttgag cagcaaaaaa
    13441 gatgagtcat tataaaaaga gcattatcgt atccgaatag cacagttata acctattaat
    13501 acgacaaaaa ccagaacaac tatgacaaaa aacgccgtaa aaaagactta aaatcaagcc
    13561 tcaagccaga ctagattcta agtcgtgcta tattgagaga tgatttgttt tagttatcta
    13621 gcccaatgcc gccacaagaa gtctgaggct ccttatctct gacagcaact agcctcccct
    13681 gctccagcag cagaacacga tgacaaatgg cctgacagat attagcatca tgcgcaataa
    13741 aaatataagt cagttgatac tcctgcttta actcatagag caagtccaat agctgccctt
    13801 gggtaatagg gtccaagcca ctcaaagcct catcaaaaat gatcacctcc ggccttaaca
    13861 aaagagctct cgctatacaa acacgctgta gctgaccacc actcagctct ctggcctttt
    13921 tacccagatg agtggcgtca agaccgaccg cagctagtat ttgaacaacc tcctctaagg
    13981 caaagtcctt agaaagggcc tctgtcaata tctcttgaat agtaaagagg ggattgactg
    14041 atcttagcgc atcctgaaag acaagtaaaa tccgaggtcc acatactttt acagaatagg
    14101 gctgaccatg aaagagcacc tgaccagctg tcggctgctc tagcccaatg attaacctag
    14161 caagcgttgt cttgccacta ccactttctc ccataatccc aaggctctca cccttttcca
    14221 tttgaaaatg acaatctgtt agcactggct tttgatgaaa gctcttataa acatgtctaa
    14281 actctatcat agcgtatcag ccgatcataa tgattttgca aaagcaactc cttggtggca
    14341 gcctgacttg gccgatgaaa aatcgactca acacttccct gttcgatgat ttttccctta
    14401 ctcatcacca gtagttgccc tcccaaagtc tgtgccaatt ggtaatcatg cgtcactgta
    14461 ataatggttt ttcccttgtc ctgcaataac ttcagcatcc gtatgatatt agaacgattg
    14521 gcatcatcta aagcagaggt aggctcatct aaaatgataa tctgtgggtc taagcacaac
    14581 aaaatagcta gcattacccg ctgtagcata ccaccactta gctcaaaggg gtacttcctc
    14641 agcagctcct ctggctgctc tagatagagc tctcgcatga aaggcagagc cctttttaga
    14701 caggcccttt ttgaaagtct ctcatggctt cggatggttt caaggagatg agcctcaatg
    14761 gtctgaaagg gattgaacat cgccatagga ttttggacca tataggccat gtggcgccct
    14821 ctaatgctct gccattgctt agcatctaat tgatctagtc tcatatcttg acaggtaatc
    14881 ctccctgtca tctgtacatt cgacgggcat tgaccaatta atagcttagt caagagggtc
    14941 ttgcccgaac cactcctgcc aacaatcacc aaggagctcc ccaagggcaa ctcaagattg
    15001 agcttactta atagcacatc agagccatta taagccgata aatcattaac aattaaccgt
    15061 tccatgtttt cctccacccc ttagcatcag cgtaatcacc taggctgtta aaagctagca
    15121 cagtcactaa aatggcaagc cctggtgaca tcatgagcca cagagctgtc ctaaaatagc
    15181 tccttgcatc atgcagcatc attccccatt ctgtcacatt gggctgaaca ccgataccca
    15241 aaaaagaaaa gcttgagatc atgagaataa tattgccaat attcatcaaa gccaacacta
    15301 caatcggccg ataaacaaat ggcaggatat gcttttttaa gatatgccgc acagataagc
    15361 ccattgtctg cgcactaatg acatatggct ctgccttagc gcttttgacc atcgtgacca
    15421 tcagcctagc ataatacagc cactctacca gaacaatagc taggatcatg ttgcctatgc
    15481 cctgcccaag tatccccatt gtagctagcg atagtaaaaa gctaggaaag gcagaaacaa
    15541 catcagctag ccacagaaaa gctgcctcga gccttccttg ataccagcct acaaccaaac
    15601 caaccacagc accaatagat agctctaaca aactaatagt aaccgccaaa agcaaggaat
    15661 acttagcccc atataacaag cgcgacagca catctcttcc caattggtca gttcctaata
    15721 agtgctgctg actaggtggc atgagcttac tagcaacatc aacagcatga ggatcaaagg
    15781 gagcaagata aggagcaaac aagacacaga taaacaacag caatagcata acagctgaac
    15841 caattacgta tttgggcatg cttcctcctt tgtcttgcgc agacgagggt caataaaaga
    15901 cactagctct tgagttatca catggtgtag taaaaacaaa gcaccaaata agagcataca
    15961 ggcctgaata accggaatat ctgctgcttt cagactcata acaaatagac tgccaatacc
    16021 attccatgag aaaatatcct caacaataat agagcccgtc atcaaataaa caaaggtcaa
    16081 gctcaagcct gttgcaatag caggaaaggc atttctaatc aggtgatgct taacaatata
    16141 ataggtctta acccctctta gcctggcatt ttcaacatgc agactcgtta gctgctcact
    16201 gattgccttt cgtatcaagg cagtatattg cccaatcaag gaaaagctaa gcgtaatact
    16261 cggcaaaatg aggctgctgg cacccgcctt gcctgacaca ggcaggagat ttagcttaac
    16321 agaaaaggct ataatcaaga gatagcccaa ccaaaagcta ggcattgaca cagcgacaaa
    16381 gctgaataaa cgcaccagcc gatcaaacaa ggaatgctca aacaaaccac tgcctacccc
    16441 caaaggaaag gcaatcacaa gtaccagtaa aaaagaggtc aagcttagca ttagcgttgc
    16501 taaaaagcgc tccaccacca aaggcaggac agggaccttt aacacgtaag aggtcccaaa
    16561 atttcctaca agaatgtcag ataaccaggt cacatactgc tcccataaag gcttgtctaa
    16621 gcccaaatag agcctagcat tgtgaagagc ttctggtgta atactgatct tagataggcg
    16681 caaatactgc tctgccgggt tagcggagga tagcttaacc agaacaaagg tcactatcga
    16741 aatcattagc aaggcgccaa aggtagaaat aagcttcttc atcatatttt ctctcaaccc
    16801 ttcactaaga catcagacaa gaattgtcag gatagtcact cacaaccagt tcctctgctc
    16861 tatcaattct tgactgcctt atcagcagca cttttttcaa tgtaacgcaa tggaagggca
    16921 ttttcctctg gtgcaaagcg cattgtctta aaatctccct tgcgatatac tgaaacaact
    16981 gactgatagg tgagtggaat ataaacagcc tcatcatgca acaatgacaa tacctgctta
    17041 tagcccttgt ctaccttatc cccatctggc tcaatcaaaa cagatttaat caggcgatca
    17101 atctcagcct ttgatggcaa actctccaag gcaatatttt ctgggtgacc atgatccgct
    17161 tttgccgtta aggctgtcat ccaagcatga ggatcccaag gagctcccca tgaataggtc
    17221 agcatcatat caaactgccc tgtcttggca ttagcccagt agtcatcctc ctccatagct
    17281 gtcaagacca catcaatccc aagctttttc cactcgcctt ggaaatattc aaccaaatcc
    17341 ttgtctgtcg ctttagttga aatataaggc acctgtaaac gcaactgctg accatctttt
    17401 tccctaatcc cttcttggtt ttccttccag ccagcggctg tcagcatgtc cttagccttt
    17461 tggagattgt attcataagg aactaagccc gcatcagcat gcggtgttgt ttttgaaaaa
    17521 atggtatctg ctgctgtctc tgttcctcta aaggtgtgct tagcaatagc ctttttgtca
    17581 accgcatggt tcattgcctg acgaacccgc ttgtcctgaa acactgactg cttagcattt
    17641 aacagcaata aacgagtcga catgggctga gaaacatcag taacatactt cttgtcctta
    17701 gcatactgca caaaggtatc aagactaatc agaccatttc catagatcaa atcaatatcc
    17761 ccagcctcaa atgctaaggc tcttgtctca gcatcaggca taatcttgat ggttacttcc
    17821 tttagctttg gtttttctcc ccaatagctc tcatgacgtg taaaggtaat gtactcattt
    17881 gcctttttct ctttaacaac ccattgacct gtaccaatcg gctttttaac attgtgctta
    17941 ttggtgtcat cgccatcagg aaaaccagca tcagccaaaa acctaatcgg tctgatcatt
    18001 gacaaatcat acaaggtagc gctataagcc tcctttagct taatctcaaa ggtatgatca
    18061 tctaaagcct tgtagctatc caattgattg gtaaagtgaa accaattatg attgccctta
    18121 ttctgctcag agaaaatcga atcaaaattc cgtttaacat tttgagcatt aaaatcagaa
    18181 ccatctgaaa atttagcctg tctcaggtta aaggtatagg ttttgccatc tgggctaatc
    18241 gtccagctct ctgctaacgc cggctcaata ttacccttgt caccatatcg aaccaagccc
    18301 tcataaacca tgtcttgaat aacaaactga tcaggattgt agcgatgagg attgacatca
    18361 ccaaaatcct caccccaagc aatcctcaac tgatccgtac ggtaagaggc ctgcttagca
    18421 ttttgacagg ccgtcagcag caaagcaaaa aagaataaca atagcacatt caatttagtt
    18481 ttcattatgt cattaacttt ctaaagatat taatctatct aattttagat gtggtttatc
    18541 acaaaattaa gtatggttaa tttaatcatt ttatagccct cttgtcaaga aaaaatgaga
    18601 caaaatcagc ctagaaaaag ccagaaggct acaaataagc aaatcgtcaa aatcatgaac
    18661 acttcaggct tgctgaggaa tattttctaa tggttattag aaataatgaa caattaccta
    18721 acaaaagact ccaaaataaa ggtaaaagac gaacattcac cttgctgctc agctaccaag
    18781 acaaacaatc ctgatagcat caattttctt taggctctta gcaattagtt gcaatatcag
    18841 ataattttga atttaattaa aaaaaacgaa actacggaga ccaattatca gaaagctatt
    18901 cacagccagc aaagggcatg ctaaagtatt atctggaaaa agaaaggctt aggaatgatt
    18961 atttctaaac taaaaggaga gagacaatga aaaaaacaat gaagaagatg ctagcagcct
    19021 cgacgctctg tatcatcatg tcaggcagct tcatcagcgg ctcagctaga gtgttagcgg
    19081 aggaatatta tgggtggaat gatgtcactg ggtctaagtc accatttcct ctatacgtga
    19141 caccaaaaaa tggagataaa aatataaaag ttcaacaaac ggttgtttac tgttttaaca
    19201 gggatgggca atggccagaa aattgggaaa aacggatata tgaatctcct gataaagttc
    19261 cacataaatt acccgaatat aataaaaagt caggaagcga taatctgttt caattactta
    19321 atcccaaaat taagataaaa aatccaatgg cagctttatt agcggttttg gaagatggat
    19381 atcctacgtc atcttcttca ggagtaaatc aaagaacaac tcagctagct atttggcatt
    19441 ttacagatgg attaagcaat cttgcccaat ttcatcttac tccggaagaa acttcagctt
    19501 ataacaagtt gatagaaaaa gggacaaatg cttctaatca aagtgaaaat aaactattaa
    19561 ataaaacttt agatatttat tcctatatag atgggactgg tgataagaaa cacaattatc
    19621 aacaccttct tggctccact ccaattccta ttgataattc taaagaaaat aaatgtcaat
    19681 gtacaaaagt tgacttaatg cgaactggag atggggttaa aatcattgtt tatgttgata
    19741 acaacggaaa taatagatat gacaacggcg acaaaatgct aaaagaagaa actatcaaac
    19801 atggtcaacg cggacctgct ggtgaatctg ggaaaccagg gcctaaaggg gatcgaggag
    19861 aaactggagc acgcgggcca gctgggcctc agggcaaacc tgggaaacaa ggacctagag
    19921 gtgataaagg agaaaccgga gaacggggac ctcaagggga aaaaggtgaa cctggaactc
    19981 ctggtcctaa aggagaagac ggtaaagacg gggctcctgg gcgtgacgga caaccggggc
    20041 ctaagggtga aaaaggtgac cctggaaaag acggacaaga tggaaaacca ggggaaaaag
    20101 gagaacctgg aattcctggt cctaaaggag aagacggtaa agatggggct cctgggcgtg
    20161 acggacaacc ggggcctaag ggtgaaaaag gtgaccctgg aaaagacgga caagatggaa
    20221 aaccagggga aaaaggtgac cctggacgcg atggtaaaga tggagaaaaa ggcgaacgcg
    20281 gtgaacaagg gcctaaagga gaacgcggtg agcagggacc tcaaggagag cgtggggagc
    20341 aaggacctcg tggggaaaat catactccta ccccagaccc aatgcctgag ccggcaccta
    20401 aaccagaatc caaacctgaa cctaagccga cacctcaacc agaggttaag cctctgccag
    20461 agactaaacc tcaaaaacca accaagccgt cagcaatggc tagccaacca agtagcaaag
    20521 cactaccaaa aacaaatgac actagcggct taatgactgt acttggaaca ggcttgctct
    20581 ctcttcttgg attaggcttc ctggcaaaac gcaaaagaaa gcaataacta acacataatc
    20641 attagtaatc cattcattat ccatttacaa gttatcataa aaaagcctta tcattccttg
    20701 actggtatga taaggctttt tgtttaccct atatagctct acccttactc caaaaatcac
    20761 ttaaccctag gaaaaggctg actatcattt ttggccaaaa aaagacagac accaattcat
    20821 gatgtctgtc tcaaaaccaa tcccttttag ggtcagtcct taattactta ttaaaatgaa
    20881 cttggatcta ccttgatacc cacaccttgt gtagttgtga tagatacgtt agtcatgtaa
    20941 gtaccctttg cagtagctgg cttagcctta accattacct catggaaagc cttaaagttt
    21001 tcaaccaact tgtcagcgtc aaatgatact ttaccaatga tagcttgtac gttacctgct
    21061 ttatcagcac gataggtaat tttaccaccc ttagactctt caaccgcctt agcaacgtcc
    21121 attgttactg taccagtttt agggtttggc atcaagttac gaggtccaag gacacgtcca
    21181 agacgtccaa caatagccat catatctggt gttgcaataa caacatcaaa atcaagccag
    21241 ccgccattga tcttagcaac aaggtcatct tcaccaacga agtctgcacc agctgccttt
    21301 gcttcttcag cttttgctcc acgagcaaaa acaaggacac gctgagtttt accagttccg
    21361 tttggcaaca ccatcgcacc acgaatttgt tggtctgcct tgcgaacgtc gatgtttaag
    21421 ttataagcaa cttctacaga agcgtcaaat tttgcgaagt tagtttcttt tgcgagtgct
    21481 acagcttcct ctacactgta tgcctttgtg ctgtccactt tttcaagtgc tgcacgcatt
    21541 tgtttgcttt ttttagccat ttttatcttc tccttgtaat gtggtcatat cgatttgatt
    21601 taaaaatctc ccacgtcact catctctatg atgaagtctt gcgggtaata agggcaggtt
    21661 gctgattaat cagtaacggt gaatcccata gaacgagcag taccttcaat catacgcatt
    21721 gcagcttcaa tgtttgcagc gtttaaatct ggcatcttag tttcagcaat ttcttgtact
    21781 tgtgcacgag taactgtcgc aactttagtt ttgttaggtg tacctgatcc tttttcaaca
    21841 cctgcagcct tctttaaaag aacagcagct ggtggtgtct ttgtgatgaa atcaaatgat
    21901 ttgtcttcgt aaactgagat aacaaccggg ataatcatac cagcctgatc agctgtacga
    21961 gcattaaatt ccttagtgaa tcccatgatg ttgatacctg cttgaccaag agctggtcca
    22021 actggtggag ctggtgtcgc tttaccagca gggatttgaa gttttacaag tttttcgact
    22081 tttttagcca tttttaaaaa tcctcctgtt gtggttttgg cggtaattca cgatttttac
    22141 ctcccacagg tatgctagag cataccttac cattatacct tattagacag ataaatcaag
    22201 tcattttcac aaaaatgtta ccgcaaatag cagatgtctc ctatggcact agcagtacaa
    22261 gcatgtgagg cttccaagga gccgcttcta gttgactttt aagcgttttt ttattataac
    22321 aaagctatgc ataagaaagt tacgatcaaa gatgtcgcac gcgaggcggg agtttctgtg
    22381 gctactgtct cctatgtcat caataacaga gaagatcaaa aaattagccc tgaaacgcgc
    22441 aataaagtgc tgcaaatgat taatctttta aattatcggc caaaccaagc cgcaaaatca
    22501 ctcgtgacac aaaaaagaca gctaatcgcc ctttactaca aagagcacag ctctgtttta
    22561 aaaagagcag agcagcttca ctttatcacc cagctatctg cctttcttta cacaaagcac
    22621 tatcacttga tttgccttaa tcaagaatac atcggaaaat atgatgtagc agatgtcatt
    22681 ctcaccctag aggtcaccaa agaggaattt tacaagatcg gaaatagcaa ctttgttcct
    22741 ttgattgcta ttgatagtat tattgatgat cccttatttt tccagattaa tagtgaccct
    22801 catctcctgt tcaataaagc cagtgcttat tttgcagggg agccctttga actggttagc
    22861 ctgcctattc aaaaccaaga aatcactcaa ggactcgctc aacagtttga taacatttgc
    22921 tggattcact ctatttgcga catcgaaagc gtgtctaagg ggaatattct agttattgat
    22981 gatactgtca atcatattct tagtaagcac aagaacaaac tatacctgcc aagtatctca
    23041 gaagctaagc ttctgaagct ttttcaggct attgagtggg cttccaaaag agaagcaatc
    23101 aacaatcata atattttggt ttaaccatga taagagctta gcaacaagct tgctgctaag
    23161 ctctttttgt tggtcaagag gccaacttta tttaggtatc agtcagtgtg ccagctcttt
    23221 tagccactaa aagcaggaat tagtttacaa gtctaccaat tgggtataaa atagacttat
    23281 gatcatctac aaattaacag ccttagcctt tattatcctg actcccttat tctctatgat
    23341 aatgatatcc ctattgagac tgggacgaag aggccttaaa tttcctgatt tagccttacc
    23401 actttttgtt tttgaaattg ttattgtatc aggaaaattt ttcacccatc atttactacc
    23461 ttattacctg attgttatgt ccttgttggc cattgttatg gcactcttac tgattatcag
    23521 aatccagcag ttttcttacc gccgattttt caaactattt tggcgagtag gctttttagt
    23581 cacactactc ttttacctga tgctagttgg tcttattttt atcgtttagt gccttaccag
    23641 acatggcttc aagcctagca gtctgaatct gccaattaac tctagcacta tcactcaaaa
    23701 ggaagctgtc tttgaacttt ctgcttgagt gggacttttt tcaaagcaat caatccatat
    23761 caaaccagca ttagagcatg cggcttgata cggattgatt gctttaagaa ctgttgtaaa
    23821 atatcaaaaa ttcagttttt aataaagtcc attagctatt tctacactaa atatcattta
    23881 agaaaacaga ggctaataac tagagttcac tataacctaa aatcaccaat acctccgatt
    23941 aacttaattt aaccaaacta ctgtatatac caaagttttt tacgtgtcat tataatacgt
    24001 tcagataaat catctaatgc acgatctttg ttgagaccaa catcatattg aatacccatt
    24061 aatctatcta gaaactcaag acgatatttc ttcataatat ttcgtgagtg tccttctgga
    24121 aaatgctcat caataagcga acttacaatc tcaactttat tactaatttt aaaatagcga
    24181 cttttcaaag attgtaattc ttctttaatt gctcttaatt tagaaaaact atctgctcca
    24241 taaaccttag cttccatttc attagcctca gaataactta gttttattgt tgcaataaaa
    24301 tttctaagta cttccttctc ttttttaagc tccctttctg tcggactcat tctatagtaa
    24361 tattgacgcc aacgatattg agaagcgttg actttttgat cacttatagt caaaatagtc
    24421 aatgctacta cactaaagaa aaatattctt tt
//
LOCUS       DARYXS010000023        24305 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.023, whole genome shotgun sequence.
ACCESSION   DARYXS010000023 DARYXS010000000
VERSION     DARYXS010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24305
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.023"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            8..95
                     /locus_tag="TV193_000748"
     tRNA            8..95
                     /locus_tag="TV193_000748"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Ser,seq:gct)
     gene            154..969
                     /locus_tag="TV193_000749"
     CDS             154..969
                     /locus_tag="TV193_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEL1512970.1"
                     /translation="MKKLNLSRLFFWLTSLALLALTLVLLFRVAISPYLSMIIRNPVT
                     KIDAIMSKPFAVIKEGAKELDSLMSAFSENKHLKKELRSYKLDQLQVDKLKSENRELK
                     ELLGLDYGTDNQFAARMISRNPYSWNKSLVIDSGKREIKEKSLVTSELGLIGRVTAVS
                     QSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTMVASEFNSNDSISLDAK
                     VYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTDNLDYVLVVGKE"
     gene            972..1475
                     /gene="mreD"
                     /locus_tag="TV193_000750"
     CDS             972..1475
                     /gene="mreD"
                     /locus_tag="TV193_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEL1512971.1"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLTDMTFPYVMTFQLAPTLIVNLLILFCFRK
                     LILSQFY"
     gene            1571..2749
                     /locus_tag="TV193_000751"
     CDS             1571..2749
                     /locus_tag="TV193_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1512972.1"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLDSKIALQNSVISNLNKE
                     QKAAQDRMKTLQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSTPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGATP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQSIGNYRGWFSPGAVSYIYPN
                     "
     gene            2854..3816
                     /locus_tag="TV193_000752"
     CDS             2854..3816
                     /locus_tag="TV193_000752"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1512973.1"
                     /translation="MSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGSVEGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEKLIVL
                     DTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            4176..4946
                     /gene="recO"
                     /locus_tag="TV193_000753"
     CDS             4176..4946
                     /gene="recO"
                     /locus_tag="TV193_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEL1512974.1"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLMEEGLDYDILTNIFEVQILDRFGVRMNFHDCVFCHRTNL
                     PFDFSHKYSGVLCPQHYHEDERRYGLDPNVIYLLNRFQTLNIDELKTISVNTGMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            5062..6069
                     /gene="plsX"
                     /locus_tag="TV193_000754"
     CDS             5062..6069
                     /gene="plsX"
                     /locus_tag="TV193_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEL1512975.1"
                     /translation="MKKIAIDAMGGDYAPKAIVEGVNQAIESFSDIEIQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYNFLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKFGALLLKSSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDVN
                     D"
     gene            6062..6310
                     /locus_tag="TV193_000755"
     CDS             6062..6310
                     /locus_tag="TV193_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514702.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1512976.1"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
     gene            6460..7170
                     /locus_tag="TV193_000756"
     CDS             6460..7170
                     /locus_tag="TV193_000756"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEL1512977.1"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            7349..11089
                     /locus_tag="TV193_000757"
     CDS             7349..11089
                     /locus_tag="TV193_000757"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEL1512978.1"
                     /translation="MNKRIFVEKKADFQIKAQVLLKELKHQLQLKTLVDLRIVQVYDV
                     FHLDQELLLTAIKHVFSEQVTDQVLSEEALQADLKRYAFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELEALKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAEDLARYRSEQGLAMEVEDLLFIQDYFKTKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINAYSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRQAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRTGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYAGLNGTEIAISESQERMAVVICPKDLEAFMS
                     ACHKENIHAAVVAAVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTVSVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAAGENIYYIPGQAISEVIDFELIKSNFMTFEAIQKKHNIS
                     SASAVKYGGVVEALALAAFGNRLGACVTLPELDRSLTAQLGGFIFTSKEEITGVIKLG
                     QTTSDFTLVVNDVKLSGARLLKAFEGSLEQVYPTVFQQAGELKPVPVVTTALAAQFKE
                     KIAQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDASVDTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRMAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVRVGDIHAVAVS
                     HGEGKLVVTERELAELCKNGQIFSQYVDLDGNPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVGID"
     gene            11208..12665
                     /locus_tag="TV193_000758"
     CDS             11208..12665
                     /locus_tag="TV193_000758"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEL1512979.1"
                     /translation="MTYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGTASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAMSLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLMTENQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTTTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEVCDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEEAYLKSLEEKVSFHIDQVTK"
     gene            12722..13744
                     /locus_tag="TV193_000759"
     CDS             12722..13744
                     /locus_tag="TV193_000759"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEL1512980.1"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHAERSKRLGVMGGLGGFGG
                     LFDLSKTGVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IAEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVKACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            13741..14298
                     /gene="purN"
                     /locus_tag="TV193_000760"
     CDS             13741..14298
                     /gene="purN"
                     /locus_tag="TV193_000760"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEL1512981.1"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYEGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            14445..15992
                     /gene="purH"
                     /locus_tag="TV193_000761"
     CDS             14445..15992
                     /gene="purH"
                     /locus_tag="TV193_000761"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEL1512982.1"
                     /translation="MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGV
                     VTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNL
                     YPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELAST
                     GSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENP
                     QQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHM
                     NPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGY
                     SKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIV
                     VTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASIRIAIAQA
                     TGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFT
                     GVRHFRH"
     gene            complement(16370..17524)
                     /locus_tag="TV193_000762"
     CDS             complement(16370..17524)
                     /locus_tag="TV193_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL1512983.1"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNVESWGRIAKHQGYHV
                     DHTPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVIIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHTQMLHASQAGSTRLAKSGTYYFSSQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNHRYIPIHKLPVQPQQHSQASIDKPK
                     PVATTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDSAPLHETDHKGR
                     IAGNQILQVGDYFVVSGTYKVLKVDQPSKGIYVQMGSRGTWLTIDKAKKV"
     gene            17915..19177
                     /gene="purD"
                     /locus_tag="TV193_000763"
     CDS             17915..19177
                     /gene="purD"
                     /locus_tag="TV193_000763"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEL1512984.1"
                     /translation="MKLLVIGSGGREHAIAKKLLESKGVEQVFVAPGNDGMTLDGIER
                     VDIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQSGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAAYGTFSDFAKAKAYIEEKGAPIVVKADGLALGKGVVVAETV
                     EQAVEAARDMLLDNKFGDSGARVVIEEFLAGEEFSLFAFVNGDQFYLMPTAQDHKRAL
                     DGDKGPNTGGMGAYAPVPHLSQSVVDTAVETIVKPVLKGMMTEGRPYLGILYCGLILT
                     EDGPKVIEFNARFGDPETQVILPRLTSDFAQNITDILEGNTANITWSDEGVTLGVVLA
                     SNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGRVYMLVTTAVTVPAA
                     QEKIYTELAQQNTEGLFYRNDIGRKAVK"
     gene            19406..19894
                     /gene="purE"
                     /locus_tag="TV193_000764"
     CDS             19406..19894
                     /gene="purE"
                     /locus_tag="TV193_000764"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEL1512985.1"
                     /translation="MKPIISIIMGSKSDWTTMQKTAEILDQFGLAYEKKVVSAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTHE
                     LN"
     gene            19881..20954
                     /gene="purK"
                     /locus_tag="TV193_000765"
     CDS             19881..20954
                     /gene="purK"
                     /locus_tag="TV193_000765"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEL1512986.1"
                     /translation="MNSTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASRV
                     SEVIVAPYSDVEALRQLTERCDILTYEFENVDADALDTVVKEEQLPQGTELLRISQNR
                     IFEKDFLANKASAAVAPYKVVTSSLDLENLDFSKKYVLKTATGGYDGHGQVVIRSEAD
                     LEEANKLANTAECVLEEFVSFDREISVIVSGNGTDVTVFPVQENIHRNNILSKTIVPA
                     RISEAVSAKSQAMAVKIAEQLNLSGTLCVEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPAVKLHAPAIMLNVLGQHMEQAQRYATENPSAHLHLYGKIE
                     AKHNRKMGHVTVFNSQSDEVEEF"
     gene            20969..21193
                     /locus_tag="TV193_000766"
     CDS             20969..21193
                     /locus_tag="TV193_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEL1512987.1"
                     /translation="MIKIIVHAFIENGETGVVEVVFASENQESISEKMTELQKQYPND
                     YLAIYDLPLDTDLSQLAHYPSIAIGKGEFE"
     gene            21790..23082
                     /gene="purB"
                     /locus_tag="TV193_000767"
     CDS             21790..23082
                     /gene="purB"
                     /locus_tag="TV193_000767"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEL1512988.1"
                     /translation="MLNRYSRPEMAKIWSEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIRANASFDINRILEIEEETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVAEKAKEHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNQERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMTRNMNSTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPI
                     LEADENITAKLRQDELDELFNPAYYTKRVDAIFDRLGL"
     gene            23380..24293
                     /locus_tag="TV193_000768"
                     /pseudo
     CDS             23380..24293
                     /locus_tag="TV193_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677204.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT         6872 a         4366 c         5821 g         7246 t
ORIGIN      
        1 attatttgga gaattactca agaggctgaa gaggacggtt tgctaaatcg ttaggtcggg
       61 taactggcgc aagggttcga atcccttatt ctccgtattg taaaggtgat tatcatactg
      121 ataatcgttt ttttattttt agaggtgatt ttattgaaaa agcttaacct atctcgtctc
      181 tttttttggt taacatcatt agctttactg gctttgacct tggttcttct ttttagagta
      241 gctatttctc catatttatc aatgattatc cgaaatcccg ttacaaaaat tgatgctata
      301 atgtctaagc cttttgctgt tataaaggag ggtgcaaagg aattagatag cttgatgtct
      361 gctttttctg aaaataagca tttaaaaaag gaacttaggt cctataaatt ggatcagtta
      421 caggttgaca agctaaaatc tgaaaatcga gagctcaagg aactgttagg gttggattat
      481 ggtactgata atcaatttgc tgccagaatg atatcaagaa atccttatag ctggaataaa
      541 tcgctggtca ttgatagcgg caaaagggaa attaaggaga agtctttggt tacttcagag
      601 cttggactta ttggtcgtgt tacagctgtt agccagtcat ctgctcatgt tgaattgtta
      661 acatctggga agaatattga gttgccgatt aaaattgtag ataaggataa ggtgatttat
      721 ggcaatttaa aggcatttaa atcagaaagt aaaacaatgg ttgccagcga atttaattct
      781 aatgactcaa tatcattaga tgctaaggtt tatacaagtg gattagatgg tgagactgtg
      841 gcagatattc ctgttggaaa ggttacgggc tttaaaaatg ctgctgataa gctaaagcgt
      901 cgtattttta taaaattgta tgctgatact gataatcttg actatgttct tgttgttgga
      961 aaagagtgaa tatgaaaaaa tcttcagagc tattagtcct tttgcctttt cttttatttt
     1021 ttgttgatgc acacgtgtca gacctgatca gctcaatgtt acctgagggt tactcggtag
     1081 tatcacacct ctttttactg tttttcctga tccttatggt agcgtttaga tctaagggag
     1141 ttatttgttt cttctctctt cttttaggat tattgtttga ttattattat tttgatcata
     1201 tagggatttt gtctcttgcc ttgccttttg gaacaatgat cgttctaggg ctattaaggt
     1261 tcttttctgg ttccattagt cagctacaat ttttcctttt ctttactctt tatatgtttc
     1321 ttgtagatgt atcaagcttt attttggcaa acagctatca gttaactgat atgacttttc
     1381 cttatgtaat gacgtttcag cttgctccga ctttaatcgt caatctcctt attttgtttt
     1441 gctttagaaa attaatatta agtcaatttt attgattatt acatacaact gtaacagatg
     1501 cgtaacatta aacgcttgat tttttgatag aatataatgt gtcttatcga aaaggagtaa
     1561 tttttttagt atgaaaaaaa gaattctatc agcggttctt gtaagcggtg tgacccttgg
     1621 aacagcaact acagtgggag cggatgattt agattccaaa atagcgttgc aaaattcagt
     1681 tatttctaat ttaaataaag aacaaaaagc tgcgcaggat agaatgaaga ctttgcaaag
     1741 tcaggttagc tcattacaat ctgaacaaga aaggttagtc gctaaaaatg gtgagcttga
     1801 agcgcgatct gctcagtttg agcaggagat tcaagtgctt gccagtcaaa ttattgctcg
     1861 taatgaaaag ttaaaaggac aggctcgtag tgctcaaaag ggaaatacgt taggttacct
     1921 caatgcactt ttgaattcta agtcaatttc tgacgttatt actcgtttgg ttgctattaa
     1981 tagagctgtg tcagccaatg cacagatgtt ggaaaagcaa aaggctgata agctttctct
     2041 tgaagaaaag caacaggaaa atcaagaagc gattaataca attgcttcaa atattacagc
     2101 aattgaatca aaccaagtag ctttaaagac tcaacaagca gatttagagg ttgccaaggt
     2161 agatttggcg cttcaattag caactgctga ggacgagaag gctagcttga ttacccgtaa
     2221 agaggctgca gagcaggcag cagctcaagc caaggctcag gcagagcagg aagcagcagc
     2281 cagagcagca caggctcaag ctcaagcaca gtctgtagcg gcagctcaag cagcagtgac
     2341 tcaagccgta ccaacaccag ctccagcgca ggcacagcct gttgtggcgc cagcagctat
     2401 ggtttcaaca ccagcggtgt cgtatgccta tgatccttct aatccgtacc ctgtcggcca
     2461 atgtacttgg ggagttaagg ctttagctcc ttgggttggc aattattggg gaaatggtgg
     2521 tcaatgggca tcaagtgcag cggcagcagg tttccgtgta ggtgcaacac caatggttgg
     2581 ctctgttgtt gtatggaatg atggtggcta tggtcacgtt gcctacgtaa caggtgttca
     2641 gggtggacag attcaagtta tggaagccaa ctatgctgga aatcaatcta ttggcaatta
     2701 tcgtggttgg tttagcccag gtgctgtatc gtatatttat ccaaattaga aaataagtaa
     2761 aggtaagaat caggattctt acctttttat ttccattgaa aaattgattg aaaagggtta
     2821 aaatggtata ggatcaaaac tttggaggaa aaaatgtctt attctgattt aaagctgttt
     2881 gcattatcgt caaacaagga attagcagaa aaagttgctg ctgcgatggg aattcaactt
     2941 gggaagtcta cggttcgcca gttttcagat ggtgagattc aggtcaatat tgaggaatca
     3001 atacgtggac accatgtttt tattttgcag tcaacaagct cgcctgttaa tgataaccta
     3061 atggaaattt taattatggt tgatgcttta aagcgtgcca gtgctgagaa aatttctgtg
     3121 gtaatgcctt attatggcta tgctcgtcag gatcgtaagg ctcgttcgcg tgagcctatt
     3181 acctctaaat tagtcgctaa tatgctagag gtggcaggtg ttgatcgttt attgactgtt
     3241 gatttacatg ctgcgcagat tcaaggcttc tttgatattc ctgttgatca tctcatggga
     3301 gcacctttaa ttgctgatta ttttgatcgt catggtctag taggtgatga cgttgttgtt
     3361 gttagcccag atcatggtgg tgtgacgcgt gctcgtaagc tggcacaatt cctccaaacg
     3421 ccaattgcta ttattgataa gcgtcgtagt gttgataaaa tgaataccag tgaggtgatg
     3481 aatatcattg gtagtgttga aggtaaaaaa tgtattctga ttgatgatat gattgatact
     3541 gctggtacca tctgtcatgc cgctgatgcg cttgctgaag caggagcaac agcagtttac
     3601 gcatcatgta ctcacccagt gctgtcagga ccagctcttg ataatattca aaaatcagcg
     3661 attgaaaaat tgattgtttt ggatacgatc tatttaccag aagaaagact gattgataag
     3721 attgaacaaa tctctattgc agatttgatt gcggaagcta tcattcgtat ccatgaaaaa
     3781 cgtccattgt cacccctatt tgaattaggg aaatgataag gttagcctga ggtagtaagc
     3841 cttaggcttt tttatgtttt aaaaggctat ttgattacca aagcagtgtt tgatttaacg
     3901 ccatagatag gcttcactgt cttatggtag gtgttgagct attatagcaa aaagtcatgt
     3961 gtaggtgctg tgtttaaaca gctagcctat gattcatata gttatggcta gtgactgttg
     4021 agcttcttat tctcagagtt gttacgagcc ttaagtacag tgttagtcat gcaattttcc
     4081 tggattttgg gtataatata gctgtattta aggtgtttta aaggtctagt aagaaaggca
     4141 ttattactag ctgagaagct tggttatgga gatatatgcg tattcagagg tcacttggta
     4201 ttgtcttgta caataaaaac tatcgtgaag atgataagct cgtaaaaata tttacagaag
     4261 cggcgggcaa gcgtatgttt ttcgtgaaac atattggtcg ttctaaacta gctcctgtgg
     4321 tccagccttt aacggctgct gattttctat tgaaaatcaa tgattcgagc ctttcttata
     4381 tagaggatta taatcaggtg gaggcttatc ggcacatcaa tgaagatttt tttaggctat
     4441 cctatgctag ttatgtcttg gctctggctg atgcggctat tccagataat gagcctgatc
     4501 ctcagttgtt tgcttttttg aaaaagactc ttgatctgat ggaagaaggg ctagattatg
     4561 acattttaac gaatatcttt gaagtccaga ttttggatcg ttttggggtg agaatgaatt
     4621 ttcatgattg tgttttttgt cacagaacca atctgccttt tgatttttct cataagtatt
     4681 caggtgtcct ttgtccgcag cattaccatg aggatgagag gcgatatggc ttggatccca
     4741 atgtgattta tttgcttaat cgttttcaaa cgcttaatat tgatgagcta aagactattt
     4801 ctgtgaatac tggtatgaaa aaaaagcttc gtctttttat tgatgccttg tatgaggatt
     4861 atgtcggtat tcgtctaaaa agtaaggttt ttattgatga tttggctaag tggggagata
     4921 ttatgaaaaa caagcagggc ttgtgagcta ttcaggtgtg gatttgtcct tttatgggaa
     4981 ttgtctgggg aatatgctat aatagttacg ttattctcta ggatattttt cgttaagaaa
     5041 aataggatta aaggagcaaa aatgaagaaa attgcaatag acgctatggg tggtgattat
     5101 gcccctaaag ctattgttga gggtgttaat caggcgatag aatccttttc agatattgaa
     5161 attcagcttt atggcgatca atcaaggatt gagtcttacc tagttaaatc agatcgtgtg
     5221 tccattgttc atacagatga aaaaattaat tctgatgatg agccagcaaa ggctattcgt
     5281 cgtaagaaga atgcttctat ggttttagct gcaagggcag ttaaggatgg tcgggctgat
     5341 gcagttcttt cggcaggtaa tacaggcgcc ttgttagctg ctggtttgtt tattattggt
     5401 cgtatcaagg gagtggatcg tcctggtttg ctgtcaactc tgccaacggt tgatggttca
     5461 ggctttgaca tgttagattt gggtgccaat gctgaaaaca cagcagagca tttacaccaa
     5521 tatgctattt taggctcttt ttatgcaaaa catgtgcgtg gtattgccaa gcctcggatt
     5581 ggcttgctta ataatggtac tgaggcaact aagggtgatt ctcttcgcaa ggaggtctat
     5641 aattttttag cttcagacag cagcctacag tttattggga atgttgaggc aagagatttg
     5701 atgtctggcg tggcagatgt tgtggtagca gatggcttta caggaaatgc tgttttgaag
     5761 tcgattgaag gcactgctat gagtattatg ggacaattga aatcagctat agcagtaggt
     5821 ggtgttaagg caaagtttgg agctctttta ttgaagagta gcctttatga cttaaaggat
     5881 actttagatt attccagtgc gggtggggct gtattgtttg gtcttaaagc acctcttgtg
     5941 aaatcacatg gttctagtga tgccaaggct atttttcata ccattaagca ggttcgtacg
     6001 atgctagaaa cagatgtagt tggccaatta gttgaggagt tttctaagga gagtgatgta
     6061 aatgactgag gaagttattt tagagaaaat catcgcatta atcaagaagc aaagaagtcg
     6121 tatagacttt gacattacag aaaaaacagc actaaaggat gatttaggag tagattcgat
     6181 tgaactggta gagtttgtta ttaatatcga agatgaattt ggtattgata ttcctgatga
     6241 agatgttgat ggcatggtat ctatgggaga tatgctaaat tatttggtca agcgtttaaa
     6301 ccaaagctaa atagttttaa aagagcacca gctctttttt tgtttccgaa aaaacgaaca
     6361 ttataagttt attttatatt aaatgtaaat aaatgttgaa tatttagtat gtttgtggta
     6421 ttgtttagat attaaatgca aagaaaggcg aacaaataag tgtctaatca actcatttat
     6481 tcaggtaagg caaaggatat ctatgaaaca gccgatgacg ggattgtctt aatctcctac
     6541 aaggatcagg tcactatgct aaatggagca cataaggaaa tgattgaagg aaaagggagc
     6601 cttaataatc agatttctgc cttaatcttt gataggctaa atagggttgg cgtatcaact
     6661 cattttatta agcaattatc cgagacagaa cagttaaata aaagggttgc gattattcct
     6721 ttggaggttg ttttacgaaa cgtggccgct ggctcatttt caaagcgctt tggtgttaaa
     6781 gaaggtcagg ctttggacga gccaattatt gagctttatt acaagaatga cgctttagat
     6841 gatcctttca ttaatgatga gcatgtcagc tttttaaagc ttgcgactga tgagcagata
     6901 gcctacatca aacaagagac gcatcgtatt aatgcttatt tgaaggagtg gtttgctagt
     6961 gttgggttga cactggttga ttttaagcta gaatttggct ttgataagga ggggatgctt
     7021 atccttgctg atgagttttc tccggataat tgccgcttgt gggataatgc gggccgtcac
     7081 atggataagg acgtttttcg tcgtcagctt ggcagtttga cgcaagccta tgagactgtt
     7141 ttagaaaggc taagagcatt ggatcaataa agaccagctt atttgttgtc agttaagaaa
     7201 gggagctctt ttttgtccgt catgtaagaa aataaatcag ttcagactat ttgagctgct
     7261 gtctaagaaa ggctgtctgc tattggagaa aagagtcagg ctagttctta ttttgggctg
     7321 gtttctgatt ggacttggta tattaactat gaataaacgt atttttgttg aaaagaaggc
     7381 tgattttcag attaaggcac aggtcctgtt aaaggaattg aaacatcagc tgcagttaaa
     7441 gacactggtt gatttgcgta ttgtgcaggt ttatgatgtg tttcatttgg atcaggagct
     7501 gcttttaaca gctataaagc atgttttctc tgagcaggtc actgatcagg tattgtcaga
     7561 agaagcttta caagcagatt taaaaaggta tgcctttttt gcgattgaag ctctgcctgg
     7621 acagtttgat cagcgtgcgg caagctctca ggaagcctta ttgttgttag gagcctcaac
     7681 tgatgtgact gttttgacct cacagcttta tttggtcaat caagacattg ctgctgaaga
     7741 attagaagcc ttaaagcagt acttgttaaa tccagtggat tctaggttta aggacatatt
     7801 agccggtctt gatgatcagg atttttcagt agcagataaa gtgattccaa cgcttgatgt
     7861 ttttaatgat tatacagcgg aagatcttgc tcgttacagg tctgagcagg gcctagcaat
     7921 ggaagtggag gatctgctgt ttattcagga ttatttcaag acaaaggggc gagtgccaac
     7981 agagactgaa ctaagggttt tggatacgta ttggtctgat cattgtcgtc acacaacctt
     8041 tgaaacagag ctaaaaacgc ttgatttttc agcttctcat tttgaaaagc agctccaagc
     8101 tacctatgag acctaccttg ctatgcgtga tgagctaggt cgatctgaaa ggcctcaaac
     8161 gcttatggat atggctacca tttttggacg ttatgaaaga gctaatggtc gtttagagga
     8221 tttggaggtt tcagatgaaa tcaatgctta ctcagtggaa attgaggtag atgttgatgg
     8281 tgtcaaggag ccttggctgc tcatgtttaa aaatgaaaca cataatcacc caacggaaat
     8341 tgaacccttt gggggtgctg caacctgtat tggtggagct attcgtgatc ctctgtcagg
     8401 ccgttcctat gtttatcaag ccatgcggct ttctggtgca ggggacatta caagcccgct
     8461 gtcagagact cgtaagggca aattaccaca gcaggttatt tcgaggcaag cagcacatgg
     8521 ttactcgtca tatggcaatc aaattgggct agcgactact tatgttcgtg agtattttca
     8581 cccaggcttt gttgccaaac gtatggagct tggtgcggta gttggtgctg cacccaagga
     8641 aaatgtggtt cgtgaaaagc caaggacagg tgacgtggtg gttttgcttg gtgggaaaac
     8701 aggacgtgat ggtattggtg gtgcgacagg atcatctaag gttcagacag ttgagtctgt
     8761 agaaacagct ggtgcagagg tccaaaaagg aaatgccatt gaggagcgta aaatccaacg
     8821 tctttttcgt cgtggcgatg tgacacgcct catcaagaag tcaaatgatt ttggtgctgg
     8881 tggtgtttgt gtagccattg gcgagcttgc tgctggtctt aacattaact tagataagat
     8941 tcctttaaaa tatgctgggc taaatggaac agaaattgcc atttcagaat cccaagagcg
     9001 tatggctgtc gtgatttgtc caaaggattt agaggccttt atgagcgcct gccataagga
     9061 aaatatccat gctgctgttg tggcagctgt gacagaaaaa ccgaatcttg ttatgacctg
     9121 gaatgggcag acgattgttg atattgaacg ctcattttta gagacaaatg gtgtgcgcgt
     9181 gtctgttgct gctaaggttg ttgacagtgg tgcgccaata ccagaagctc gtcaaactac
     9241 tgctgagaca cttgaagcag ataccattgc tgtcttatca gacctgaacc atgctagtca
     9301 aaagggtttg caaaccctgt ttgatagctc agtgggtcgc tctacagtaa tacatccgct
     9361 tggtgggcgc tatcaaatga cacctgttga aggctctgtt cagaaattac cagttcaaca
     9421 tggagtgaca aagacagtct ctgttatcgc tcaaggctat cacccttata tagccgaatg
     9481 gtcaccttat catggtgctg cttatgctgt aattgaggca actgctcgtc tggtcgcaac
     9541 gggtagccat tggcataagg cacgcttttc atatcaggaa tatttccaaa gaatggataa
     9601 gcaggcagag cgctttggtc aaccggtggc agccttgctt ggagcaattg aagcacaggt
     9661 gcagcttggc ttgccttcta ttggaggtaa ggattcaatg tctggtagct ttgaggaatt
     9721 gacagtgccg ccgaccttgg ttgcctttgg tgtgacgact gctcatgtag atcatatcct
     9781 ttcaccagaa tttaaagctg ctggcgagaa tatttactat attccaggac aggctatttc
     9841 ggaagtgatt gattttgagt tgataaaatc taattttatg acttttgagg ctattcagaa
     9901 aaagcataat attagctcag cttcggctgt taaatatggt ggtgttgttg aagcactggc
     9961 tcttgctgcc tttggtaatc ggttaggggc ttgtgtgaca ttaccagagc ttgacaggag
    10021 cttaacagct cagcttggtg gctttatctt tacatcaaaa gaggaaatca caggtgttat
    10081 caagcttggt caaactacca gtgactttac attggttgtc aatgatgtca agctatctgg
    10141 agctcgtctc ttaaaggctt ttgaagggag cctggagcag gtttacccga cggtatttca
    10201 gcaggcaggt gaattgaagc ctgttcctgt agtgacaaca gcacttgctg ctcagtttaa
    10261 ggaaaaaata gctcagccag ttgtctatat tccagttttt ccaggaacta actcagaata
    10321 tgattcggct aaggcctttg aaagagaggg tgcaagggtg aacttggtgc cttttgttac
    10381 cttgaatgag gcagctattg acgcttcagt tgacacgatg gttgaccata ttcatcaagc
    10441 tcatattatc ttccttgcag gtggtttttc agcggcagat gagccagatg gttcagctaa
    10501 atttattgtt aatatcctgc tgaatgagaa ggttcgaatg gcgattgatg cctttattga
    10561 aaagggtggt ctgattatcg gtatttgtaa tggctttcaa gctctggtca aatcagggct
    10621 gctgccatat ggacgttttg aggcggtaca tgaggctagt ccaactctgt tttataatga
    10681 tgccaatcag catgtggcta aaatggtaga aacgcgtatt gccaatacca attctccttg
    10741 gctggcaggt gtcagggtgg gggatattca tgctgttgca gtgtcacatg gagagggcaa
    10801 gcttgtggta acagaaagag aattagcaga gctttgtaaa aatggtcaga tttttagcca
    10861 gtatgttgac cttgatggta atccaagcat ggatagcagg tataatccaa atggctctgt
    10921 caacgctatt gaaggtctta ccagcaaaaa tggtcagatt atcggtaaga tgggacattc
    10981 agagcgcttt gaagagggac ttttccaaaa tattccgggt aataaggatc aatggttatt
    11041 ccgaagtgcg gtgcattatt ttagaggaga ccatgtgggt attgactgaa ctgggatata
    11101 gccttgtaat agctaagata gctgctatta ttgctcagcc tagctgttag ttctagctta
    11161 gttaatgaca caatcataat taaaagggca ttagcccaga ggtaaagatg acatatgacg
    11221 taaaatctct taatgaggaa tgtggtgttt ttgggatttg gggacaccca catgccgctc
    11281 aagtgactta ttttgggctt catagcctac agcaccgcgg ccaagaggga gcaggtatta
    11341 tttcaaatga taatggggag cttcatcagc atcgtgatgt aggtctcttg tcagaggtgt
    11401 ttaaggattc atctgatctg gacaagctaa agggacatgc tgccattggt catgtgcggt
    11461 atgcgactgc tgggacggct tccattaata atattcagcc ctttttatat cgttttacag
    11521 acgctcaatt tggcttgtgc cacaatggta atttgaccaa tgctatgtca ttgaaaaaag
    11581 cgttagagag tgagggagct atttttaatg cctcttctga tacagaaatt ctaatgcatt
    11641 tgattcgtcg tagtcatcac ccagaatttt taggaaaggt aaaagaggca ctcaacactg
    11701 ttaaaggggg ctttgcttac ctgctgatga cagagaacca gctgatagca gcgcttgatc
    11761 caaacggctt taggccgttg tctataggcc gtatgaaaaa tggggcttgg gtcgtctcaa
    11821 gtgagacctg tgcctttgaa gtggttggtg ctgagtgggt tcgcgatgtg atgccaggtg
    11881 aggtcattat cattgatgat caggggatca cttatgactg ctatacgact actacgcagc
    11941 tggctatctg ctctatggaa tatatttact ttgcgcgtcc tgattcaacc attgctggag
    12001 tcaatgttca caccgctcgc aagcgaatgg gaaagagact ggctcaggaa tttcagcatg
    12061 aggctgatat tgtggttggt gtgccaaatt cctcattatc agcagcgatg ggctttgcag
    12121 aagcatcagg cctgccaaat gaaatgggat tggtcaagaa tcaatatacc caacgaacct
    12181 ttatccaacc aactcaggag cttcgtgagc agggagttcg aatgaaactt tcagctgttt
    12241 caggtgttgt caagggcaaa agggttgtga tggtagatga ttctattgtc agagggacaa
    12301 cctcacgacg cattgttaat ttgctgcgtg aagcaggagc tacagaggtt catgtagcaa
    12361 ttggtagccc tgagctcaaa tacccttgct tttatgggat tgatattcag acaagacggg
    12421 agctgatttc agctaatcat actgctgctg aggtctgtga tattatcggt gctgatagcc
    12481 tgacttattt gtcacttgat gggcttatcg aggctattgg acttgataca aaagcaccaa
    12541 atggtgggct ttgtgtggct tattttgacg gtcagtatcc aacgccgctt tatgattatg
    12601 aggaggctta tctcaagagc ttagaagaaa aggtaagctt tcacattgat caggtgacga
    12661 agtagcgctt tatggctaac atagaataaa tgatctaggc agctaaaata aggaggagaa
    12721 aatgtctaaa aatgcttatg ctcaatcagg tgtcgatgtt gaagcaggct atgagcttgt
    12781 tgagcgaata aaaaagcatg ccgagcgtag caaacgattg ggtgttatgg gtggtctagg
    12841 aggctttggt ggtctgtttg acctgtcaaa gactggtgtt aaggagcctg ttttggtttc
    12901 agggacagat ggcgtcggaa caaagctaat gcttgcaatc cagtacgata agcatgacac
    12961 gattgggcag gattgtgtgg caatgtgtgt caatgatatt attgcagcag gtgccgaacc
    13021 cctgtatttt cttgattacc ttgcagcagg aaaaaatgag cctgccaaat tagagcaggt
    13081 gattgcaggt attgctgagg gctgtgttca agcaggtgct gctcttatcg gtggagaaac
    13141 tgctgagatg cctggtatgt atggtcaaga tgactatgat cttgccggtt ttgcggttgg
    13201 tattgctgag aaatctcagc tgattgatgg ttcaagagta gctgagggag atcatctcct
    13261 aggtttggca tcaagtggag ttcattcaaa tggttattcc ttggttcgtc gtatttttgc
    13321 cggttatact ggtgaggagc tgcttccaga gcttgatgga aaaaagctta aggaggtact
    13381 tcttgagcca actcgtattt atgtcaaggc tgtgttacca ctcattaaaa gcggcttagt
    13441 ggcaggaatc gctcatatta cgggtggcgg ctttattgaa aacctacctc gtatgttttc
    13501 caaagaacta gccgctgaaa ttgaagaagc cagcttacct gtgctgccca tttttaaagt
    13561 ccttgagaca tatggtaaga tcaatcatga agaaatgttt gagattttta atatgggtat
    13621 tggcatggtg cttgctgtca agcctgagca cgttgagcag gtgaaggcct gtcttgatga
    13681 gcctgtgtat gacattggtc gcgttgtgac cagaacagtt gctagtgtgg tgatgaagcc
    13741 atgacaagaa ttgccgtttt tgcttctggt aatggctcca attttcaaac gattgcagaa
    13801 cagtttccgg ttgcctttgt tttttctgat cattgcgatg ctcatgtttt aagtagagcc
    13861 tgtgctttgg gtgttctgtc ctacagcttt gaactaaagg actttgagaa taagcaagcc
    13921 tatgagcaga ctcttgtggc attgctgcag cggcatcaga ttgatctcat cgtccttgcc
    13981 ggctatatga aaattgtgag tacaacctta cttgatgctt acgaaggaaa aatcatcaac
    14041 attcacccag cttatttgcc agaatttcca ggagcacatg gtattttaga tgcttggcaa
    14101 gcaggtgtta gtcagtcagg agtgactgtt cattgggttg atagtggtat tgatacagga
    14161 aaaatcatca aacaggtacg agtaccacgt ttgagtgatg atactcttga aagctttgaa
    14221 gccagaattc atgaagcaga ataccaattg tatccagagg tactggatag tcttggagta
    14281 gagcggctta accgctgatt gtgtaagatt aataactatt ttccctattg tggcatttcg
    14341 tttatcatag cagctgcgct aatggtggct aacaaaggct agaagacttg tttgatgatg
    14401 gcactgctat tgaggaaaat agacttttct aaggagaact taaaatgact aaacgcgcct
    14461 taattagcgt atcagataaa agagggattg tggaccttgc tagggagctt aagcatcttg
    14521 gctgggatat tatatcaaca ggaggaacaa ggcttgctct tgaagaggct ggtgtagtta
    14581 ctgttgctat tgacgatgtg acaggctttc ctgaaatgat ggacggacgg gtaaaaacgc
    14641 tgcaccctct cattcatggt ggcttacttg ctcgtcgtga cattgagcac cacttacagg
    14701 cagcaaagca aaacaggatt gaattaatag accttgttgt tgttaacctt tatcccttca
    14761 aagaaaccat ttgccgtcca gatgtcactt atgatgtcgc tgttgatatg gttgatattg
    14821 gtggtccttc actgctgcgt tcagcggcta aaaatcatgc tagtgttacg gtagtggttg
    14881 atccgacaga ttatccgctc gttttaggag agttggctag cactggcagt acaagttacc
    14941 aaacccgtca aagcttagca gctaaagctt ttcgccatac tgcagcctat gatgcagtga
    15001 ttgcagatta ttttacaaga caagcaggtg agacaaagcc tgaaaagctc acgcttacct
    15061 atgatttgaa gcaaagcatg cgttacggtg aaaatcctca acaggctgca gatttttacc
    15121 aaagagcgct cccaacaacc tattcaattg cttcagccaa gcagctaaat ggaaaagagc
    15181 tatcattcaa caatattcgt gatgcagatg ctgcgattcg tattattcgt gattttaagg
    15241 agcgtccaac cgttgtagca ctcaagcata tgaatccatg tggtattggt caggcagatg
    15301 atattgagac agcttgggat tttgcttatg cagctgatcc ggtgtctatc tttggtggta
    15361 ttgttgtcct aaatcgtgag gtggatctag cgacagcgga gaagcttcat gctatttttc
    15421 ttgaattgat cattgcacca ggctattcca aagaagcgct agctgttctc acccataaaa
    15481 agaagcactt gcgaattctt gaattgccat ttgctgctca ggaggctagt gaaatagaag
    15541 cagaatatac aggagttctt ggtggtctac tagtgcaaaa tcaagatgtt gtcacagagt
    15601 ctccagcgga ttggatagtg gtgacaaagc gtcagccaaa tgaacaggaa atggctgctc
    15661 tagcatttgc ttggaaaacc atcaaatatg tcaagtctaa tgcgattgtc attgctaatg
    15721 atcatatgac tttgggcgtt ggtccagggc aaacaaaccg aatagcctct attcgtattg
    15781 ctattgcgca agcaacgggg cagcttgagg gagcagttct tgctagcgat gccttcttcc
    15841 catttgcaga cagcattgaa gaaattgctg ccgctggtat caaggctatt atccagcctg
    15901 gaggctctat tcgtgattca gaatctattg cagctgccaa tcagcatggt ataaccatga
    15961 ttttcacagg tgtgaggcat tttagacatt aataaagtaa aaagagactg gagccaaaag
    16021 agttgcactt tagaaattct tggttaatat actttattac ctagttggat tcattaaaaa
    16081 gcgaacaagt ctagttttca taatctcaga aaactagact tgtttgcttg ttttatttgg
    16141 tggtcatact attgtttcag cctcttttta ctatgactaa tacaagaatt tatgaaggaa
    16201 caaggcttta ttttttgttg tggtaacagt gaccagatcc gttatcaatc agtatttgag
    16261 tattttgagc tctagatgca tcacttagat aggatattgc aaaggataca gctgctgcat
    16321 gtattaggaa agcattatca taaaaggctt tttcgttagc ctaaaggttt tagaccttct
    16381 ttgccttatc tattgttaac catgttccac gtgaacccat ttgcacgtaa atccccttgc
    16441 taggctgatc aacctttaga accttatagg ttcctgaaac gacaaaataa tcacccacct
    16501 gcaaaatctg atttccagca atacgtcctt tatggtccgt ttcgtggagt ggagctgagt
    16561 ctatccagtt taaggaggtt ggctctccac cggctaattc actgcttgca atcatgttct
    16621 gagcgacctg atcgacccga aaaacaccag gaaaggctac agtatctcca accttgatag
    16681 gagtggtcgc cacaggcttt ggtttatcta tagaggcttg actatgttgc tgaggctgaa
    16741 ccggcaattt gtgaattgga atgtagcgat gatttcctga atgaccgata tagctgagcc
    16801 attcatagcc atcagcgaca agggtttgat catagtgcac taactgtcca gtatgatagt
    16861 aagctaaatc aggacttgct aatgtagctt cagcctttat aggactttgg cttgaaaaat
    16921 aataggtacc acttttagct agacgagttg atcctgcttg agaagcatgt aacatttgtg
    16981 tgtggctggt agagttgtga tccagatcct tgaagtgaat gtaaccactt acctgatgct
    17041 tatgaatctg tcgtttatga tacttttcag gtccctgtcc ggcattatag ttgtattcct
    17101 caataataac agtgtcacca ttgacctctg ctacccaggc gacgtgtcca tatagggcat
    17161 gtgactggtt aaagccctta tcccaccaag caacagcacc aactctaggt gtatgatcaa
    17221 catgatagcc ttggtgttta gctatacgtc cccagctttc aacattacca tagcctctag
    17281 gcaggctgaa tccatttgag gaatgcagtc ggaatgctac aaaagaagtg cattgacgta
    17341 agtacatgtt ccaaggatca gctccgaagc cctgtttcca cttacttgga tagttatccc
    17401 ctaaaacagc agcgtgtacg atacctgact gaccttgtga aatcgttgtt gtggcagagg
    17461 atattgcacc attaccacct aaaaggattg ctcctgaagc taacaattga tagacttttt
    17521 tcattaatta cctcctgtaa cttactattc gcaagaaaga ggacaaaaat gtccttgatt
    17581 taaaaaaatg taaggaaaaa tattttagcc tcaaaatact gttggtgctc cctagcttcc
    17641 aagagccaat aggcaagccc atctccagct tgcctgctcc ctgtagctaa aagcaattta
    17701 tagtaacact agcacctcat ctgaagaggc aggctgtggt aattaatgcc aataatctgt
    17761 aaaaagagac agcaggtatg gttatatgag ctatgatggt tatattctat aaagcttatt
    17821 ttttagcttc gggctttctt tggtgattag ttatttatat aaacgaacaa ttatgctaaa
    17881 atatgtttat aaaattcgtg ttatgaggtg tgtgatgaag cttttagtta tcggttcagg
    17941 tggtcgtgaa catgcgattg ctaagaaatt gttagagtca aaaggcgttg aacaggtttt
    18001 tgtggcacct ggcaatgatg gcatgaccct tgatggcata gaacgggtag atattgatat
    18061 ttccgaacat tctgctttga ttgcttttgc aaagaccaat catatagcct ggacctttgt
    18121 gggaccagat gacgcattag cggctggtat cgttgatgag tttaaccagt ctggcttgaa
    18181 agcctttggg ccctctcgtt tagcagcgga gctggagtgg tcaaaggact ttgctaagca
    18241 aatcatggtc aaatacggta ttccaacagc agcctatggc acattttctg attttgcaaa
    18301 agccaaggcc tacatcgagg aaaagggcgc gccaattgtg gttaaagcag atggtttggc
    18361 gctaggaaag ggtgttgtcg tagcagagac tgtagagcag gcagttgagg cggcgcgtga
    18421 catgctcttg gataataaat ttggtgattc aggtgcgcgc gtggtgattg aggaattttt
    18481 agctggtgaa gagttctctc tctttgcctt tgtgaatggc gatcagtttt acctcatgcc
    18541 gacagcgcag gaccacaagc gggctcttga tggtgacaag gggccaaata caggtggtat
    18601 gggggcttat gcaccagtgc ctcatctttc tcaaagtgtg gtggatacag cagttgagac
    18661 cattgtcaag cctgttctaa aagggatgat gacagagggg cgtccctatc ttggaatcct
    18721 ttactgtggc ttgattttga cagaagatgg accaaaagtg attgaattca atgctcgctt
    18781 tggtgatcct gagactcagg ttatccttcc tcgcctgacc tctgattttg cacagaacat
    18841 taccgatata ttagagggca acacagctaa tatcacatgg tcagacgagg gagtgacgct
    18901 cggcgttgtc cttgcttcaa acggttatcc gcttgcttac aagaaaggtg tgcttctgcc
    18961 agcaaagacc actggcgaca tcattaccta ctacgcaggg gttaagcttg cggaaaatgg
    19021 caaagcactg ctgtcaaatg gtggacgtgt ctatatgctg gtcaccacag cagttaccgt
    19081 cccagctgcg caagaaaaaa tctataccga acttgctcag caaaataccg aaggattatt
    19141 ctaccgaaac gatattggaa gaaaagcagt aaaataaatt agcgctagct caagctaccg
    19201 aaggtcgcta tgatgacaat gacttattat cggtgagcaa aagcgagcct aacacgatac
    19261 ttttcgccgt agcgcaaaga gtgacaaggt cactcggggg aacttgaaag accttgggct
    19321 ttcaagttag tcatgagaca cctatggtgg ctgttgacgc ccccccccac ttaagaaaag
    19381 tatcaaaaac ctttaaggag aaagtatgaa accaattatc tctatcatca tgggctccaa
    19441 atctgactgg accaccatgc aaaaaaccgc cgaaatcctc gaccagtttg gccttgccta
    19501 cgaaaaaaaa gtggtctctg cccaccgcac gccggatctc atgttcacat acgctgagaa
    19561 agcacgcgaa cgtggcatta aaatcatcat cgctggtgct ggcggagcag cccatctccc
    19621 tggaatggtc gctgcaaaga cgacacttcc tgttatcggc gtacctgtca aatcgcgtgc
    19681 tcttagtggt cttgattcgc tgtattcaat tgtgcagatg ccaggtggtg tgcctgtggc
    19741 aactatggcc attggagagg caggagcaac caatgcagca ctgactgctc ttcggatcct
    19801 ttcaattgag gatgaaacaa tcgcagagca gctcagccat ttccacaaag agcaaggacg
    19861 gatcgcagag gagtcaaccc atgaactcaa ctaaaacaat tggaattatc ggaggtggtc
    19921 agctgggaca gatgatggcg atttctgcca tttatatggg gcataaggtc attacactgg
    19981 atccagcagc ggattgccca gcctcgcgcg tgagtgaggt tatcgtggcg ccttatagtg
    20041 atgtggaggc gctgcgtcaa ttgaccgagc gctgtgatat tttgacctat gaatttgaaa
    20101 atgtggacgc tgacgccctt gatacagtgg taaaggagga gcagctgcct caaggaacag
    20161 agttacttcg gatctcgcag aatcgtattt ttgaaaaaga ttttttagcc aataaagcaa
    20221 gcgcggcagt ggcaccctac aaggttgtaa cctctagcct cgacttggaa aaccttgact
    20281 tttcgaaaaa atacgtcctc aagacagcga caggtggcta tgatggacac ggtcaagtcg
    20341 ttattcgctc cgaagcagac cttgaagagg ctaataagtt ggctaacact gccgagtgcg
    20401 tcttggaaga atttgtcagc tttgaccgag agatttccgt tattgtatct ggcaatggca
    20461 cagatgtcac tgtctttcct gttcaggaaa atatccatcg gaacaatatc ctgtcaaaaa
    20521 ccattgtccc agctcgcatt tcagaagcag ttagcgctaa atcgcaggct atggcggtga
    20581 aaatagcaga gcagcttaac ctatctggca ccctctgtgt agaaatgttt gtggcaggcg
    20641 acgagatttt ggtcaatgaa atcgccccac gtccccacaa ctcaggacat tactccatcg
    20701 aagcctgtga tttctcccag tttgacaccc acattttagg tgtattaggc cagccattac
    20761 cagctgtcaa actccatgcc ccagccatta tgctcaacgt cctcggccag cacatggaac
    20821 aagcccaacg ctacgccaca gaaaacccta gcgcccacct ccacctctat ggtaaaatag
    20881 aagccaagca caaccgcaaa atgggacacg tgacggtgtt taacagtcaa tcagatgagg
    20941 ttgaagaatt ttaggaggaa ttaatcctat gataaaaatc attgttcacg cttttattga
    21001 aaatggtgaa acaggtgttg ttgaagttgt ctttgcttcg gaaaaccaag aatccatttc
    21061 tgaaaaaatg acggagctac aaaagcaata tccaaacgat taccttgcta tctatgattt
    21121 accactagat acagacctat cgcaattggc ccactatccg tcaatagcga taggcaaagg
    21181 ggagtttgag tagttaagga agattagtat ttcggattga gtgttattgg gacaatttat
    21241 ggctatgcct ttcaaaagat tggtcatgat gttgagcatg ttgtgagaat tgagaatcgt
    21301 aatcagattt cagaagttgg taaatgactt aatggataat tctagatact gatctcgagc
    21361 aatcataaga gaaatgttga aattgtagct tctggaggtg tagaactcaa aaattatcgt
    21421 ggtgagatat ttccatataa aacttctaag cgtatttcgt ctagattgat aacatataga
    21481 taggtttgta cataatgaac ttactagatg catcatgaca aagcagatct tttatataca
    21541 tgcaaagagg tttacaatat tggtatagtc aactattgat gccctaactt ttaatcacaa
    21601 tatagaaatt attgcgaata gactttaaaa gcattactat taactatgta gaaaggaaat
    21661 gagcgctaga attttcaaac tgaacctgag cggaaagctc ggaatttaga taaatttcct
    21721 cggacgtaaa tgtccgtctt tagctttcta aaattcagtt gctttctggc tgttcttggt
    21781 atcttaatta tgctaaaccg ttattcacgc cctgagatgg cgaagatttg gagtgaagag
    21841 aacaagtacc gtgcttggtt ggaggtggaa atcctcgctg atgaggcatg ggctgagttg
    21901 ggtgagattc ccaaggaaga tgtggcgaag attcgcgcca atgcgagttt tgacatcaat
    21961 cgtattttgg agattgaaga agagacccgt cacgatgtgg tggcctttac tcgtgcggtg
    22021 tctgaaacgc tcggtgagga gcgcaagtgg gtccactatg gcttgacatc gactgacgtg
    22081 gtggatacgg cctatggcta tctctacaag caggctaatg acattatccg tcgtgacctt
    22141 gaaaacttta ccaacattgt ggctgagaag gctaaggagc acaaaatgac tatcatgatg
    22201 gggcgtactc atggtgtgca cgcggagcca acgaccttcg gtctcaaatt ggcgacctgg
    22261 tacagtgaaa tgaagcgtaa tcaagagcgt tttgagcatg cggctgctgg tgttgaggcc
    22321 ggtaaaatct caggtgctgt tggaaacttt gccaatatcc caccatttgt tgaggagtat
    22381 gtctgtggca agctaggcat tcgcccgcag gaaatctcaa ctcaggtctt gccacgagac
    22441 cttcatgccg agtacttcgc agtgcttgct agtatcgcga catcaattga acgcatggca
    22501 actgaaattc gaggcctgca aaaatctgag caacgtgagg tagaagagtt ctttgccaaa
    22561 ggacaaaagg gaagctctgc catgcctcat aagcgtaacc cgatcggctc tgaaaacatg
    22621 acggggcttg cgcgtgtcat tcgtgggcac atggtgacag cctatgagaa cgtggcgctt
    22681 tggcatgagc gtgatatttc gcactcgtca gcagagcgga ttatcacacc agacacgact
    22741 atcctcatca actacatgct caaccgtttt ggcaatatcg tcaaaaattt gacagtcttt
    22801 ccagaaaaca tgactcgtaa catgaactct acctttggct tgatttacag ccaacgtgtg
    22861 atgcttaagc tgatcgaaaa aggcatgacg cgtgaggagg cgtatgactt ggtacagcca
    22921 aagacagcct attcatggga caaccaagtg gacttcaagc cgatccttga ggcagacgaa
    22981 aatatcactg caaaattaag gcaagatgag cttgatgagc tcttcaatcc agcttattat
    23041 accaagcgtg tcgatgctat tttcgaccga ttaggattat aggaagaaaa cagcgcgtct
    23101 ttttagactg tagctaagcc cagatttgtt taaaaagtct tgaaaatgaa ttcctcggag
    23161 ctaattctca aaatgaagaa tagtatttca agagaggctg tcactagcta tatcgcttaa
    23221 gaaaatgctc taaaatagac attttttcaa tctgagaagg caataggcct tctttttttc
    23281 taaaaataca gaaatgttat tatagaatgg agtcaaaaaa ttaataatta attaaattat
    23341 gtgatataat gaaagaaata gtgtcttgaa gagggaaaca tgttagacaa ttttggtgaa
    23401 aaggtgagag accttcggta tcagaaaaaa attaccagag aggatttatg tggagatgag
    23461 tcagaattat ccattcgtca attggcacga atagaactgg gccaatcgat tcccagccta
    23521 tcaaaggtgg tttttattgc taaggctttg gacgttagtg tcggcttttt gacagacgga
    23581 gaggatttgg agctaccgaa gcgctatagg agcttaaata tttgatttta agaacaccga
    23641 cctatatgga cgatgacaaa ttaaagctgc gagaagagca atttgacgaa atttttgaag
    23701 attattatga ccagttgcca gaggaagaaa agcttgtggt ggattgcttg cagtccataa
    23761 tggatacgtt attaaccgag aatatcaatt ttggagttgg gttattacag gaatactttg
    23821 aacaaacaaa aagtaagact caatttagag agaatgatct cattcttatt gagctgtatt
    23881 tagcgtacct cgacattgca ggaatgaatg gagagtattc agataaagga ttctatgatt
    23941 ctttgttaga cattttgtta aatcagtttg aacattttga attagaggaa ttatttattg
    24001 tcaataaaat agctatagga atttcctcgt tgagcatcaa aaacaataag ccggagattc
    24061 ttgagaaggt tattgtactt agtcaaaaaa ttatcctcaa gactcaggat tttaatagaa
    24121 tgcctatctt aaatttgata gagtggaaat atgctctaat gaagaaaaaa gacatagaaa
    24181 tggccaaaaa atgctatgct aaggcatgcc tgtttgctca attaacagga gatcagtatt
    24241 tggaaaagaa attgagagaa gaatggggta aagatataaa acgatatcaa taggacaaaa
    24301 atgtc
//
LOCUS       DARYXS010000024        24267 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.024, whole genome shotgun sequence.
ACCESSION   DARYXS010000024 DARYXS010000000
VERSION     DARYXS010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24267
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.024"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            112..1716
                     /locus_tag="TV193_000769"
     CDS             112..1716
                     /locus_tag="TV193_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156117153.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1512989.1"
                     /translation="MFLRNNKQKFSIRKLSAGAASVLVATSVLGGTTVKANSEVSRTA
                     TPRLSRDLKNRLSDIAISRDASSAQKVRNLLKGASVGDLQALLRGLDSARAAYGRDDY
                     YNLLMRLSSMLNDKPDGDRRQLSLASLLVDEIEKRIADGDRYAKLLEAKLAAIKSQQE
                     MLRERDSQLRNLEKEKEQELQKAKDERQALTESFNKTLSRSTKEYNKLKTELAKEKEK
                     AAKMTKELADKLSNAEASRDKAFAVSKDLADKLSSAEASRDKAFAVSKDLADKLAAKT
                     AEAEKLMENVGSLDRLVESAKREMAQKLAEIDQLTADKAKADAELAAANDTIASLQTE
                     LEKAKTELAVSERLIESGKREIAELQKQKDASDKALVESQANVAELEKQKAASDAKVA
                     ELEKEVEAAKAEVADLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEM
                     LEKKDHANADLQAEINRLKQELADRIKSLSQGGRASQTNPGTTTAKAGQLPSTGESAN
                     PFFTIAALTVIAGAGMAVVSPKRKEN"
     gene            1939..4158
                     /locus_tag="TV193_000770"
     CDS             1939..4158
                     /locus_tag="TV193_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEL1512990.1"
                     /translation="MVKEINLSGEEVVALAAKYMTDGDVELVQKALDYATAAHFYQVR
                     KSGEPYIVHPIQVAAILADLHLDAVTVVCGFLHDVVEDTDITLEDIEFDFGKDVRDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNEIEFYKISHMMREKRREREALV
                     DDIVTKIKAYTTDQGLYGDVYGRPKHIYSVYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKTNGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGIRGKVNQVEQKVGMNWIKELVELQAASNGDAKGFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKDSGPIDFAYAVHTQVGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSINKGRELLVSYFQEQGYV
                     ANKYLERKRIEEILPKVSVKSEESLYAAVGFGDISPVSVFNKLTERERREEERAKAKA
                     EAEELVKGGEVKHENKEILKVRSENGVIIQGASGLLMRIAKCCNPVPGDVIEGYITKG
                     RGIAIHRADCNNIKSQDGYQERLIEVEWDLEHSSKDYQAEIDIYGLNRIGLLNDVLQI
                     LSNATKSISTVNAQPTKDMKFANIHVSFGIPNLAQLTAVVEKVKAVPDVYSVKRTNG"
     gene            4173..4616
                     /locus_tag="TV193_000771"
     CDS             4173..4616
                     /locus_tag="TV193_000771"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEL1512991.1"
                     /translation="MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDY
                     AVRKISHMRIFSDPEGKMNRSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDRA
                     SQLYNSFNAQLEQLVPVQRGVFGADMQVSLINDGPVTIILDTKYR"
     gene            complement(4743..6035)
                     /locus_tag="TV193_000772"
     CDS             complement(4743..6035)
                     /locus_tag="TV193_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL1512992.1"
                     /translation="MLTSKRLYHLGKTPLEIGTVVIGLFTMTLGAPAVKANHYKVGWA
                     WSSSSRVANHYKYEDTTKPIHSKDYQETTGLYLMVNITGVDNTNHTIVSPHYQDIRLE
                     YGKTYTTNEMIKLVQDVIDPSAESFKVISLKNAKLTKASTAEILSTDHFTTPIKGQYH
                     QKDQTYILTGQVLVEKVSKVALKDIKVTDKAGNPIQDSDAVAVTQHVKFLKKDNGQLV
                     NVDVTDSLGKEGLTGLRYYGSRVSSEELFEAAKKAFETTQAFKDGYQLVKRISTTVTQ
                     DPDITHQSHNGEIYSGASERMVYHADRDEDFNYIIDSNRIAQVYNSKYDVNNPISYAT
                     HSDSVVETYFISKDINDDYSTTYRSVTIYQQDKQQQLINEYTFKTHEAITTETIDKYL
                     KGLPNTFQAKNGTSYQFTGSLTPISETEFIAVYKDLQK"
     gene            6790..7638
                     /locus_tag="TV193_000773"
     CDS             6790..7638
                     /locus_tag="TV193_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEL1512993.1"
                     /translation="MALKDYFPDMQEGAFPLADQDWISVEVGEQYLHFPKSSLSEREQ
                     LLLGLGRQRKEPSKDQKSPWYHYLILGQGEQPEEFQGCQFIYINHQCPLAGDLIELLK
                     GIIEGVEAVLPISQTRTAFLVCHHSRSDLFQLLANLLPTIESDFGLALMIFIGNGWYQ
                     VSGNALRDYFKEENAVFTAYLAEHSASRLLTFSEVMLWSLLANSGLPALSKHFSQLLL
                     ANKEVMDLVLAMWQEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLYLKQLDDLAFAY
                     LFILKH"
     gene            7788..8921
                     /gene="ugpC"
                     /locus_tag="TV193_000774"
     CDS             7788..8921
                     /gene="ugpC"
                     /locus_tag="TV193_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEL1512994.1"
                     /translation="MVELNLKHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVVVKDGQIISEDGLDIAIPEG
                     QAKMLEAAGYKGKKVIFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHNPGEKVSLTFNVAKGHFFDLETEQAIR"
     gene            9105..10724
                     /locus_tag="TV193_000775"
     CDS             9105..10724
                     /locus_tag="TV193_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEL1512995.1"
                     /translation="MEKHWWHKATIYQIYPRSFMDTSGNGIGDLKGITGKLDYLQELG
                     ITAIWLSPVYQSPMDDNGYDISDYQAIAAIFGDMADMDELLDEAKQRGIKIIMDLVVN
                     HTSDEHAWFVEARENPDSPKRDYYIWRDQPNNLMSIFSGSAWEYDDASGQYYLHIFSK
                     KQPDLNWENAELRQSIYDMMNFWIDKGIGGFRMDVIDLIGKIPDSEITGNGPRLHEYL
                     KEMNQASFGNHDLMTVGETWGATPEIARQYSRPENKELSMVFQFEHIGLQHKPNASKW
                     DYAAELNVPALKEIFSKWQTELKLGEGWNSLFWNNHDLPRVVSIWGNDTVYREKSAKA
                     MAILLHLMRGTPYIYQGEEIGMTNYPFERLSDVNDIESLNYAKEAMANGMSEEAVLDC
                     ICRVGRDNARTPMQWSSQKNAGFSTADQTWLPVNPNHQEINVASALADPDSVFYTYQK
                     LIQLRQTQDWLVEADYQLLETSDKVFAYKRQLGRETYLVVVNLSNQEQFFEESLHKAQ
                     VIISNTDVQAVVESQQLEPWDAFCVKLDETL"
     gene            10833..11195
                     /gene="traF"
                     /locus_tag="TV193_000776"
                     /pseudo
     CDS             10833..11195
                     /gene="traF"
                     /locus_tag="TV193_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623564.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
     gene            11309..11668
                     /gene="yajC"
                     /locus_tag="TV193_000777"
     CDS             11309..11668
                     /gene="yajC"
                     /locus_tag="TV193_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEL1512996.1"
                     /translation="MGLPTILMFVVMIGLIWFMQRQQKKQAQERQNQLNAIEKGDEIV
                     TIGGMFAVVDEVDLAAKRIVLDVDGVYLPFELSAIKRVVEKGSAVTSADVDTTETAVD
                     DTAVEASDEAESAIETN"
     gene            11842..12591
                     /locus_tag="TV193_000778"
     CDS             11842..12591
                     /locus_tag="TV193_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEL1512997.1"
                     /translation="MFGLKAKSKKIVLDRIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKN
                     NVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFMPWQSAYSELY
                     FTPVLWPDFKRAELLKAIEDYNHRHRRFGAI"
     gene            12601..13395
                     /locus_tag="TV193_000779"
     CDS             12601..13395
                     /locus_tag="TV193_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEL1512998.1"
                     /translation="MRERFIWGGVAAAVFLPFLLIGSLPFQLFVGVLAMIGVSELLRM
                     KRLEVFSFEGVFAMLAAFVLTVPLDHYLTFLPMDASFACYGLLVFFLLAGIVISSDSY
                     GFEDASFPIAASLYVGIGFHNLVNARMTGIDKVFLALFIVWATDIGAYLIGRRFGKRK
                     LLPKISPNKTIEGSLGGIVSAVLVSFVFMLFDKAVYAPHHFGTMLILVALFSIFAQFG
                     DLVESAVKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            13427..14692
                     /gene="rseP"
                     /locus_tag="TV193_000780"
     CDS             13427..14692
                     /gene="rseP"
                     /locus_tag="TV193_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEL1512999.1"
                     /translation="MLGIITFIIIFGILVLVHEFGHFYFAKRSGILVREFAIGMGPKL
                     FSHVDQQGTLYTIRLLPLGGYVRMAGWGDDTTEIKTGTPASLTLNDQGLVKRINLSQS
                     KLDPTSLPMNVTAYDLEDKLTITGLVLDEIKTYSVDHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILFAFVQGGVADYHSNHIRVVENGAAAKAGI
                     RDNDQILEINHQKINDWYELTQAVTDSAADVKAKGKLEITYQTGDQVKTIALKPEKKG
                     DQYLIGVQYPLKTSLTDKLIGGFEMAGNGALVIVTALKSLITSFSLDKLGGPVAMYQM
                     SNQAAKNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNVIEALRRKPLKQETET
                     YITLAGVAIMVVLMIAVTWNDIMRAFFQG"
     gene            14962..16818
                     /locus_tag="TV193_000781"
     CDS             14962..16818
                     /locus_tag="TV193_000781"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEL1513000.1"
                     /translation="MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRT
                     NLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATS
                     EYKSSSKVTALDDLVEIETPNCKTIDEVAAFLDVAEHQVIKTLLFMVDHEPVLALLVG
                     NDQINAVKLKNHLGADFLEPASEEEARAILGAGFGSLGPVHLTDGIRIVADRKVQDLA
                     NAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDRHGVLQFARGIEIGHIFK
                     LGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQEAQDLTERVEASLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN"
     gene            16870..17427
                     /locus_tag="TV193_000782"
     CDS             16870..17427
                     /locus_tag="TV193_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEL1513001.1"
                     /translation="MTIEELQQLVLADHELMTILSIIETLPLKDCWLAAGAIRNAIWN
                     HLAYGIGFDPLTDVDVVFFDPEISYEAEQLLEEQLKCAYPMYQWEVRNQAYMAAHNPK
                     TPPYRSSQDAITKYPERCTAIAVRLVGGQLEVFAPYGLADISHFVCRPTPHFLEDSER
                     MDCYRQRLAKKDWHKKWPQLTYHDC"
     gene            17762..22159
                     /locus_tag="TV193_000783"
     CDS             17762..22159
                     /locus_tag="TV193_000783"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEL1513002.1"
                     /translation="MSDLFGKLMEQIEMPLEIRQSSAFSSADIIEVKVHSVSRLWEFH
                     FSFAEVLPIESYRELSDRLVRTFEAADIKVTFDIKAETINYSDQLLQAYYQEAFEHEP
                     CNGASFKSSFSRLQVRYDHHQLIIMAPDFVNNDHFRKNHLPNLAAQFERFGFGRLAID
                     MVSDQEMTDHLTKDFETNRQALVEKAVQDNIAAQQSLEAMQPPAEEAAPSPSLDYRER
                     MAQRQASFDKAVITPMIEVDTEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     AMQKWAKDDDELRKFDLIAKGAWLRVQGNIENNPFTKSLTMNVQQVKAIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVEDLIDTAARWGHQAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISFNPVAMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIIEQFDEFINPGHPLSAFTTELTGITDNHLVGAKPIQQVLEAFQAFCQGTIL
                     VAHNASFDVGFMNANYDRYGLAKISQPVIDTLELARNLYPEYKRHGLGPLTKRFQVSL
                     EHHHMANYDAEATGRLLFIFLKEAREKHGITNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNVKYFEGVPRIPRTVLDQHREGLLLGTACSDGEVFDAVLTQG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGVEQIIRDLIEVGRRAEKPVLAT
                     GNVHYIEPEDAIYRDIIVRSLGQGALINRTIGRGEAAKPVPLPEAHFRTTNEMLDDFA
                     FLGQDLAYEVVVQNTQALADRIEKVEVVKDDLYTPYIDKAEETVAELTYQKAFAIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQQSEFITDGSVGSGYDLPNKACPRCGTLYKKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPNAHLDVRDIFGEEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYPDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQFPADDVTAS
                     WQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPITIPADDPDVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERSSY
                     IKAMRQNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLAAVKARMEDISNKRKRNEASNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSEATEFQIEGDTLIPPFIALEGLGENVARQIVKARQDGEFLSKMELRKRGGAS
                     ATLVDKMDELGILGNMPDDNQLSLFDDFF"
     gene            22281..22709
                     /locus_tag="TV193_000784"
     CDS             22281..22709
                     /locus_tag="TV193_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1513003.1"
                     /translation="MNELDKNPALKAMVVFRKAQRTLDAQSSAFFQKANLTPTQFSVL
                     EVLYSKGSMRINKLIGSLLATSGNMTVVLKNMERNGWISRCQDAKDKRACLVQLTPEG
                     KALIETILPEHIKRVEALFSVLTETEQKQLITLLKKFKEL"
     gene            22839..23384
                     /locus_tag="TV193_000785"
     CDS             22839..23384
                     /locus_tag="TV193_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1513004.1"
                     /translation="MKQILIINGSLRTGSFNHQLAQAAEQLLEGKAAVSYLDWEQVPM
                     FSQDLEASTPESVAGVREAIQAADAIWIFSPVYNFAIPGSIKNLLDWVSRALDLSDPS
                     GPSAINGKVVTVSSVANGGHEQLFAQYQDLLPFIRTTVVGNFTKAAVNPEAWATGVLD
                     ISEETRQSLAAQAEALLEAIH"
     gene            complement(23563..24177)
                     /locus_tag="TV193_000786"
     CDS             complement(23563..24177)
                     /locus_tag="TV193_000786"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1513005.1"
                     /translation="MSAQDKLIKAQHLIDMNDIIREGNPTLRAVAKEVEFPLSDDDII
                     LGEKMMQFLKHSQDPVMGEKLGLRAGVGLAAPQIDVSKRIIAVLVPNPEDSEGNPPKE
                     AYSMEEVLYNPKIVSHSVQDAALADGEGCLSVDRVVEGYVVRHARVTVEYYDKHNEKH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFEAKEGMLILN"
BASE COUNT         6904 a         4780 c         5838 g         6745 t
ORIGIN      
        1 acaatgtact gcataaagaa gttcctgtca ttaaaataaa agtgccatga ggttataata
       61 gtatggtaaa acaaaaaagt gtgcccataa cgggtagaga ggaattgaca tatgtttttg
      121 agaaataaca agcaaaaatt tagcatcaga aaactaagtg ccggtgcagc atcagtatta
      181 gttgcaacaa gtgtgttggg agggacaact gtaaaagcga actctgaggt tagtcgtacg
      241 gcgactccaa gattatcgcg tgatttaaaa aatagattaa gcgatatagc cataagtaga
      301 gatgcctcat cagcccaaaa agttcgaaat cttctaaaag gcgcctctgt tggggattta
      361 caggcattat tgagaggtct tgattcagca agggctgcgt atggtagaga tgattattac
      421 aatttattga tgcgcctttc atcgatgtta aatgataaac ctgatgggga tagaagacaa
      481 ttaagtttgg cttcattact tgtagatgaa attgaaaagc ggattgctga tggagatagg
      541 tatgcaaaac ttcttgaggc taaacttgca gctattaaat ctcaacaaga aatgcttaga
      601 gaaagagatt cccaacttcg aaatctagag aaggaaaaag aacaagaact acaaaaagct
      661 aaagatgagc gtcaagctct taccgaatca ttcaacaaaa ctttatcaag atcaacaaaa
      721 gagtataata aactaaaaac agaacttgca aaagaaaaag aaaaagcagc taagatgact
      781 aaggaattag cagataagct aagcaatgct gaagcaagtc gtgataaagc ctttgcagta
      841 tcaaaagatt tagcagataa actaagtagt gctgaagcaa gtcgtgataa agcttttgca
      901 gtatcaaaag atttagcaga taaattggca gctaaaacag cagaagctga aaagttaatg
      961 gaaaacgttg gtagtctaga ccgcttggta gagtctgcaa aacgtgaaat ggctcaaaaa
     1021 ttagcagaaa ttgatcaatt aactgctgat aaggctaagg ctgatgcaga gcttgcagct
     1081 gcaaatgaca ccattgcatc acttcaaaca gagctagaaa aagctaagac agagcttgct
     1141 gtttcagagc gtttgattga atcaggcaaa cgtgaaattg ctgagctaca aaaacaaaaa
     1201 gatgcttctg ataaggcttt agtagaatca caagctaatg tagcagagct tgaaaaacaa
     1261 aaagcagcat cagatgctaa ggtagcagag cttgaaaaag aagttgaagc tgctaaagct
     1321 gaggttgcag atcttaaagc acaattagct aagaaagaag aagagcttga agccgttaag
     1381 aaggaaaaag aagcgcttga agctaagatt gaagagctca aaaaagctca tgctgaggaa
     1441 ctttcaaaac ttaaagaaat gcttgagaag aaagaccatg caaatgcaga tcttcaagca
     1501 gaaatcaatc gcttgaagca agagctagct gacaggatta agtcattgtc acaaggtggt
     1561 cgtgcttcac aaacaaaccc aggcactaca actgctaaag caggtcaatt gccatctact
     1621 ggtgagtctg ctaacccatt cttcactatt gcagctctta ctgtcatcgc tggtgctggt
     1681 atggctgtgg tgtctcctaa acgcaaagaa aactaagcta tttcctcttt ccccaatgga
     1741 caatagccga aataatagag cgactatcgt tctaacacaa aagcaacagt ctcctgtctg
     1801 ttgctttttg tgatattagg gctcatcagt ctaggctaat ggttttctgc gctttatctg
     1861 cagctttgag gattccttct tttgctttta cagtgaaagt gttaaaatag gaaaaacaac
     1921 tagtaattga ggaagtaaat ggttaaagaa atcaatttat caggagagga agtagttgcc
     1981 cttgctgcca agtacatgac agacggtgac gtcgagcttg tgcaaaaggc gcttgattat
     2041 gcgacagctg ctcattttta ccaggttaga aagtcggggg agccttatat tgtgcaccct
     2101 attcaggtag cagcaatcct agcagacctg catttggacg ctgtgacagt tgtctgtggc
     2161 tttttgcatg atgtggtaga ggatactgat attactctag aggacattga gtttgacttt
     2221 ggtaaggacg ttcgtgacat tgttgatggg gtcacaaagc ttggtaaggt agaatacaag
     2281 tctcacgagg agcagctggc tgaaaaccac cgcaaaatgc tcatggccat gtcaaaggac
     2341 attcgtgtga ttttggtcaa gctagccgac cgactgcaca atatgcgcac cctcaagcac
     2401 ctccgtaagg acaagcagga gcggatttct cgtgaaacca tggaaatcta tgccccgcta
     2461 gcccatcgct tggggatcag tcggatcaag tgggagctgg aggatctagc ttttcgctac
     2521 ctcaatgaga tcgaattcta caaaatctct catatgatga gagaaaagcg gcgggagcgc
     2581 gaagctttgg ttgatgatat tgtcactaag attaaagcct acaccaccga tcaagggctt
     2641 tatggtgatg tctatggccg tcctaagcac atctactcgg tttaccggaa aatgcgtgac
     2701 aagaaaaagc gctttgatca gatatttgac ttgattgcga tccgttgtgt catggagaca
     2761 caaagtgatg tttacgcgat ggtcggctat attcatgagc tctggcgtcc catgcctggc
     2821 cgcttcaagg actacattgc agcgcctaag accaatggct atcagtcgat tcacacgact
     2881 gtttacgggc caaaaggacc gattgaaatt cagattcgga ccaaggaaat gcatcaggtc
     2941 gctgagtatg gggtagcagc ccactgggcc tacaaaaaag gtattcgtgg caaggtcaat
     3001 caagtcgagc aaaaggttgg tatgaattgg attaaggagc ttgtcgagct tcaggctgcc
     3061 tcaaatggcg atgctaaggg ctttgttgac tcggtgaagg aggacatctt ttcagagcgt
     3121 atctatgtgt tcacaccgac aggagcagtg caggaattgc ccaaggattc aggccctata
     3181 gactttgcct atgccgttca cactcaggtt ggtgaaaagg cgacaggagc caaggtcaat
     3241 ggccgcatgg tgcccttgac agccaagtta aaaaccggtg atgtggtgga aattgtcacc
     3301 aatccgaatt cctttggtcc tagtcgtgac tggattaagc tcgtcaagac caataaggct
     3361 cgtaacaaga ttcgccaatt ctttaaaaat caggacaagg agctgtctat caataaagga
     3421 cgtgagcttc tggttagtta ttttcaagag cagggctatg ttgccaacaa gtaccttgag
     3481 cgtaagcgta ttgaggagat tttaccaaag gtcagtgtta aaagcgagga gtctctctat
     3541 gccgctgttg gctttggcga tattagccca gtcagtgtct ttaataaatt aaccgaaaga
     3601 gaaaggcgtg aggaggagcg tgccaaggct aaggctgaag ctgaggagct ggttaagggc
     3661 ggtgaggtca agcatgaaaa caaagagatt ctcaaggtcc gcagtgaaaa tggcgtgatt
     3721 atccaagggg cgtctgggct tctcatgcgt atcgccaaat gctgcaatcc cgtaccagga
     3781 gatgtgattg aaggctatat taccaaggga cgaggcattg ctattcaccg cgcagactgt
     3841 aataacatca agagtcagga cggctatcag gagcgtctca ttgaggttga gtgggatttg
     3901 gagcattcta gcaaggatta ccaagctgag attgatattt atggtttaaa tcgtatcggc
     3961 ctgctcaatg atgtcctgca aatcctatct aacgccacca agagcatttc aactgtcaat
     4021 gcccagccga ccaaggacat gaagtttgcc aatattcatg tgagctttgg cattcctaat
     4081 ctggctcagc tgacagctgt tgttgaaaag gtcaaggcgg ttccagatgt ttacagcgtc
     4141 aaacgaacca acggataaaa aggagaccaa ccatgaaaat tgtgattcag cgcgtcaagg
     4201 aagcctcagt gtcgattgat gggaaaatag ctggcgctat tgatcaaggg ctgctgctgc
     4261 ttgttggcat aggtccagat gatcaggcag aggatataga ctatgcagtg cgtaaaatca
     4321 gtcatatgcg gattttttca gaccccgagg gcaagatgaa ccgatccatt caggacattg
     4381 agggcagtgt cttgtctatc tcgcagttta cgctatatgc tgacaccaaa aagggcaacc
     4441 gacctgcctt caccggggct gctaagcctg acagggccag ccagctttat aacagcttca
     4501 acgctcagct agagcagctt gtaccggttc agcgaggggt ctttggtgcg gacatgcagg
     4561 ttagtctgat caatgatggc ccagttacga ttatcctaga tacgaagtat cgataactgc
     4621 ctagcgatcg atcgtttgct taggagagtc atataaagga aaaacaaaaa gacgagtggt
     4681 atgagaagca ctcgtctttg tcgtttatgc tgctgtgttg aagctagcta gggctactag
     4741 tcttattttt gcaggtcttt gtagactgcg atgaattctg tctcagaaat tggggttaag
     4801 ctgccagtga attggtaaga agtaccattt ttagcttgga aagtattagg taaaccttta
     4861 aggtatttgt cgatagtctc agtggtaatt gcttcgtgtg ttttaaaggt gtattcgtta
     4921 atcagctgct gctgtttgtc ctgttggtaa atagtaactg aacgataggt tgtgctatag
     4981 tcatcgttaa tatccttaga aataaaatag gtttctacaa cagaatctga atgtgtcgca
     5041 tagctaatgg gattgttgac gtcatacttt gaattatata cttgagctat cctgttagaa
     5101 tctatgatat agttaaagtc ctcatcgcga tcagcatggt agaccatgcg ttcactagct
     5161 ccactgtaaa tctcaccgtt atggctttga tgagttatat caggatcctg cgtgactgtt
     5221 gtactgattc gcttgacgag ctgatacccg tctttgaaag cctgagtggt ttcaaaagcc
     5281 tttttagcag cttcaaagag ctcctcagaa gagaccctgc tgccatagta tcttaacccg
     5341 gtaagtcctt ctttaccaag gctgtcagtt acatcaacat taacaagctg cccattgtct
     5401 tttttgagga atttaacgtg ctgtgtcaca gctacggcat ctgaatcttg gattgggttt
     5461 cctgccttat ctgttacctt aatgtccttg agagctacct tgctaacttt ttccacaagg
     5521 acctgacccg tcaagatgta tgtttggtct ttttgatgat actgtccttt gattggtgtc
     5581 gtaaaatggt ctgtgctaag tatttcagct gtagaagctt ttgttaattt ggcatttttc
     5641 aaactaatga ccttaaagct ttctgctgaa ggatctatga cgtcttgaac tagctttatc
     5701 atctcatttg tggtgtaggt tttgccatat tctagtctaa tatcctgata atgtggagat
     5761 acgatggtgt gattagtgtt atctactcca gtgatattga ccatgaggta cagtcctgtg
     5821 gtttcttgat agtcttttga atggattggc ttagtggtgt cctcgtattt atagtgattt
     5881 gctaccctac tagagcttga ccatgcccac ccaactttgt aatggtttgc tttaacggca
     5941 ggtgctccca aggtcatggt gaatagtcca atgactacag ttcctatttc taaaggtgtt
     6001 ttcccaaggt gatacagtct ttttgaagtc aacatatttc aaacctccct aaatcctgtc
     6061 agtctctata gttataaaaa tacagagaat cgttagaaga attaatgttt catgccggca
     6121 agatgagtgt aacaaaagat tggtgccgat acaagaagat ggagattaga gcatctggtt
     6181 tcaatgagag ttacataata gcagaaggtt ttttcactat gagagctaat cgtcttaaaa
     6241 tggtataata gcaagtgaat aggctatcta actggtttaa cagccatttt tagagaagct
     6301 taatagtatt gctgataagt gactcgtatc tccatattgc ttttcaaagg ctatgttagc
     6361 tatgataagc gtgaccaggc tatcggaaaa tccagtgttc ttaaaggctt tgaagctctg
     6421 gctttgaacc ttagctctgg tgtttctatg aaaatgactt gggccttgta ccagataaga
     6481 atgaagtcaa attgaggttt tttgacaaaa tgtttgagta aatacaagtt catagaagtc
     6541 taatgtataa aaatacaatt gtatcgccat aatctgaatg accaaaccat taaaaaaata
     6601 aaatttttaa acattttgga aaacgctttc aaaactaaaa agaactgtcc tatagtcatt
     6661 gcttagcatt aaagcaaggt gtgaaatgtt atcatatgga gaaataggct gtcttgtgct
     6721 gtatctgtgc caaaaaagaa tgcttgtttt tgtgatataa tgtgactaag aaacctgaaa
     6781 ggaatgctta tggcattaaa agactatttt cctgatatgc aagagggtgc atttcctctg
     6841 gctgaccaag attggattag cgttgaggtt ggggagcagt acctccattt ccccaaatcc
     6901 agcttgtcag agcgagagca gcttttgctt ggtttggggc ggcagcgcaa agagccgtcc
     6961 aaggatcaga aatctccttg gtatcattat ttgattctgg gccaagggga gcagccggag
     7021 gagtttcagg gttgccagtt catctatatc aaccatcaat gtcctttagc aggtgatttg
     7081 attgagcttc taaaggggat catagaggga gttgaggctg ttttgcccat tagccagacc
     7141 aggacagctt ttttggtctg tcaccatagc cgttcagacc tttttcagct cttagcaaat
     7201 ttattgccca cgattgagag cgattttggt ttggccttga tgatttttat cggtaatggc
     7261 tggtatcagg tgtcaggaaa tgccttgaga gactatttta aggaagaaaa tgctgtgttt
     7321 acagcttatc ttgctgagca ctctgccagt cgcttgctga ccttttcaga ggtcatgctc
     7381 tggtcactct tagcaaacag tggtttgcca gccttgtcaa agcattttag tcagctgctt
     7441 ttagccaata aagaggtcat ggatctggtg ctcgccatgt ggcaggagca tggcaacctg
     7501 gtacagacag cccagcgctt gtatattcat cgcaattcgc tgcaatataa gctggataag
     7561 tttgctcagc agtcaggtct ctatttaaag cagctagatg acttggcctt tgcttatcta
     7621 tttatactga agcattagat ttgtgcaggg tgcccaaaga catttgggcg ttttgtctat
     7681 atgatgaaaa cgctatcttt gctataataa aagcatcaaa taaaaagtgt cagggttgct
     7741 agcattgcag tcagctagca gcctatctga cccattagga gtaacgcatg gttgaattaa
     7801 acttaaagca catctataag aaatacccaa ataccacaca ctatgctgtt gaggatttcg
     7861 atttagacat taaggataag gaatttatcg tttttgtagg gccttcaggc tgtggtaagt
     7921 caacaacgct tcgtatgatt gctgggcttg aggatatttc agagggtgaa ttgaaaattg
     7981 acggtgaggt tgtgaatgac aaatcaccaa aggaccgcga tatcgcgatg gttttccaaa
     8041 actatgccct ttacccgcat atgaccgttt atgacaacat ggcctttggt ctcaagctac
     8101 gtaaatacaa aaaagatgat attgatcgtc gtgtcaagga agcagcagaa atccttggct
     8161 tgacagaatt tttagaacgt aagccagcag acctttctgg tggtcagcgt cagcgtgtgg
     8221 ctatgggacg tgctatcgtg cgtgatgcca aggtattctt gatggacgag cctttgtcaa
     8281 acctagacgc taagctgcgg gtgtcaatgc gtgctgaaat tgcgaaaatt caccgccgta
     8341 tcggctcaac aacaatctac gtaacgcacg accagaccga agcgatgacc ttggcagatc
     8401 gtatcgttat catgagtgcc actaaaaacc ctcaaggcaa cggtacaatc ggaaagattg
     8461 agcaggttgg ctcaccacag gagctctata acctaccggc caataaattt gttgcaggct
     8521 ttattggaag ccctgcgatg aacttctttg aggtggttgt caaggacggt cagatcatca
     8581 gtgaggacgg gcttgatatt gctattccag aaggtcaggc taaaatgctt gaagcagctg
     8641 gctataaggg caagaaggtt atttttggta tccgtccaga agatatttca agcaaccaaa
     8701 tcgtgcatga cacctatcca aatgccaatg tcacagcaga ggtcttggtt tctgagctgc
     8761 ttggatctga aaccatgctt tatgttaagc ttggtcaaac agagtttgct tcacgagttg
     8821 atgcgcgtga cttccacaat ccaggtgaaa aggttagctt gaccttcaat gttgctaagg
     8881 ggcatttctt tgatctagaa acagagcaag ctattcgcta ataacacctc ctagaataaa
     8941 atcctcatct tgcttgagga ttttttaaca aaagaaaatg caagcgattg cgctatcaaa
     9001 aagaaaaagg gatttatcat aaagacaaca gatgttctgt agtgctaggc gatcataatg
     9061 atggcacgaa atagcaggag actgtttagt aataaggaga tatgatggaa aaacactggt
     9121 ggcataaagc gacaatttat caaatttacc caaggtcctt catggataca agtgggaatg
     9181 gtattggtga tttaaaagga atcacaggta agctggatta tctacaggag ctagggatca
     9241 cagctatttg gctgtctcca gtttatcaat caccaatgga cgataacggc tatgatattt
     9301 cagactatca ggccattgca gctatttttg gtgatatggc tgatatggac gagctgcttg
     9361 atgaggccaa gcagcggggg atcaaaatca tcatggattt ggttgtcaat cacacctctg
     9421 atgagcacgc ttggtttgtg gaggcaagag aaaatcctga cagtcctaaa cgagattatt
     9481 acatttggcg tgatcagcct aataatctca tgtcgatctt ttctggctct gcttgggaat
     9541 atgatgatgc ctctgggcag tattatctgc acatattcag taaaaaacag cccgacttga
     9601 attgggaaaa tgctgaattg cgtcaaagca tttatgacat gatgaatttc tggattgata
     9661 aggggatagg tggctttcgc atggacgtca ttgacctgat tggtaagatt ccggattctg
     9721 aaattacagg caatggccca aggctgcatg aatacctcaa ggagatgaac caggcaagct
     9781 ttgggaatca tgacctgatg actgttggtg aaacatgggg cgctacaccg gaaattgctc
     9841 gtcagtattc acgtcctgaa aataaggagc tgtcaatggt ctttcaattt gaacatatcg
     9901 gcttgcagca taagccaaat gcttctaaat gggattacgc agctgagttg aatgttccgg
     9961 ctctcaagga gatttttagc aagtggcaga cagagctaaa gctaggtgaa ggctggaact
    10021 cccttttttg gaacaatcat gacttgcctc gtgtcgtctc catttgggga aatgatacag
    10081 tatatagaga gaagtctgcc aaggcaatgg ctattttgct gcatttaatg cgtgggacac
    10141 cttatattta tcagggtgaa gagattggca tgaccaatta cccctttgag cgcttgagtg
    10201 atgtgaatga tattgaatca ctgaattatg ccaaggaggc tatggctaat ggcatgtcag
    10261 aggaggctgt tcttgattgt atttgtaggg tgggtcgaga caatgcaaga acaccaatgc
    10321 aatggagcag tcaaaagaac gccggctttt caactgctga tcagacctgg ctgcctgtca
    10381 acccaaatca tcaagagatt aatgtggcta gtgctctagc tgatcctgat tctgtttttt
    10441 acacctatca aaagcttatt cagctgcgtc agacacagga ttggctggtg gaggcagatt
    10501 atcagctgct ggaaacatca gataaggttt ttgcctataa gcgtcagctt ggtagagaga
    10561 cttaccttgt tgttgtcaat ctgtctaatc aagagcagtt ttttgaagaa agtcttcata
    10621 aggcccaagt gattatcagc aataccgatg tgcaggcagt cgtagaaagt caacagctgg
    10681 agccttggga cgccttttgt gttaagcttg atgagacctt gtagcctagc tgcttgctgt
    10741 gcctcagctc aataatcgta gcgattcttt gagaattttg acaaattgct gtatgattag
    10801 tagaagaatt agatacaaaa gaggaggctg agatgaccgt tgaagaaacc atgacctttg
    10861 caaaaagcat tgcagcattt agataggtag agattagtga ggtagtcact aggctagcag
    10921 caggtgagga catcaccgtc tttttaggca gagcgacctg tccttattgt cgtcgctttg
    10981 cacccaagct agcaagcgta gcaaggcagg agcataagga tattttcttt gtagatagtg
    11041 aagactcaac agagcttgca gacctgcagg cctttcgtga gcgctatggg cttgctactg
    11101 tgcctgccct gctcattagt cgtcatcagg aggtcaaggc agtctgtgat tctagcttga
    11161 ctgaggaagc cattttggct ttcctagagc agtgacagac agctaattat ctggtgcaag
    11221 taatagaaat gtaatcagtc atgtcttgct atgtgagtcc aaatctgcta tagtaggaca
    11281 tgacttttag acgaaataag gagatattat gggcttacca acaattttaa tgtttgttgt
    11341 catgattggt ttaatttggt ttatgcagcg tcagcaaaaa aagcaggcgc aggagcgcca
    11401 aaatcagctt aatgcgattg aaaaaggcga tgagattgtg acgattggtg gcatgtttgc
    11461 agtggtcgat gaggttgatt tagcagcaaa gcgaattgtc ttagatgttg atggtgtcta
    11521 tctgccattt gagctatcag cgatcaagcg cgtggtcgaa aaaggaagtg cagtgacatc
    11581 agctgatgtg gatacgacag agactgcagt tgatgacaca gcggttgagg cttcagacga
    11641 agctgaatca gctattgaga caaattaaga aaatgaggtc tgaagcatta gtgtttcaga
    11701 cttttttagg tgatgatagc aggtagccag acagagctgt catgtgctat ggaaatatcg
    11761 tctacaacga gaaaaagcga gccaaaccgc atgaaatatg gtaaaatatg aggtaagtat
    11821 gcttgtgaat aaggaaaaaa catgtttgga ttaaaagcga agtcaaaaaa aatcgttttg
    11881 gataggattc caaagcacat tgggatcatc atggatggta atggacgctg ggcgaaaaaa
    11941 cgcttaaagc cgcgtgtctt tggacataag gcgggtatgg acgctttgca ggaggtaacg
    12001 attgcagctt cagatttagg ggttaaggtg ttaacagtct atgccttttc gacagaaaat
    12061 tggtcaagac cacaagatga ggtgagcttc attatgaacc tgcctgttga gttttttgat
    12121 aagtatgtgc ctgagctgca caaaaataat gtcaaggtgc agatgatcgg tgagaccaac
    12181 cgcctaccta aggatacact aaaggccttg gaagcagcta ttgctaagac aaggcaaaat
    12241 actggcttga ttctaaactt tgctcttaat tatgggggtc gcgcggaaat caccaatgct
    12301 gtcggtctca ttgctcaaga tgtcctagac gccaagctga accctggtga cattaccgag
    12361 gatttgattg ccaactattt gatgacggat catttgccct atctctatcg cgatcctgac
    12421 cttattatca gaacgagcgg tgaattgcgc ttgagtaatt ttatgccttg gcaatcagcc
    12481 tatagtgagc tttactttac gccggtgctg tggcctgatt ttaaaagagc tgaactacta
    12541 aaggccatag aggattataa ccatcgtcat cgccgtttcg gtgctattta aggagagagt
    12601 atgagagaac gtttcatttg gggtggtgtt gcagctgctg ttttcctacc ctttttactc
    12661 attggcagct taccctttca attgtttgta ggtgtgcttg ccatgattgg tgtatcagag
    12721 ctgttaagaa tgaagaggct tgaggtcttt tcctttgagg gtgtttttgc catgctagca
    12781 gctttcgttt tgacagtgcc gttggatcat tacctgacct ttttgccgat ggacgctagt
    12841 tttgcttgtt acgggctgtt ggtgtttttc cttttagcag gaatagtgat tagcagcgat
    12901 tcttatggct ttgaggatgc tagctttccg attgcagcta gcttatatgt tggtattggc
    12961 tttcataatc tggttaatgc gcgaatgaca gggatagaca aggtttttct ggctcttttt
    13021 attgtctggg cgactgatat tggagcttac ttgattgggc gccgatttgg taagcgaaag
    13081 ctcctgccaa aaatatcacc caacaaaaca attgagggca gccttggtgg tatagtcagt
    13141 gcggtgcttg tttcctttgt gtttatgctc tttgataagg ctgtttatgc tcctcatcat
    13201 tttggaacaa tgttgatttt ggtggctctt ttttctattt ttgctcagtt tggagatttg
    13261 gttgaaagtg ctgtcaaaag acatttcgga gttaaggact caggcaaatt gattccaggc
    13321 catggtggta ttttagatcg ttttgattcg atgatctttg tttttcccat tatgcatcta
    13381 tttgggttat tttaaagctc attatcaata gactgaaagg aaatctatgt taggaataat
    13441 tacctttatt attatttttg gtattcttgt gcttgtccat gagtttggcc atttctattt
    13501 tgctaaacga tctggtattt tagtcagaga gtttgctatt ggcatgggac caaaactctt
    13561 ttcgcatgtt gatcagcaag gaacgcttta cacgatccgg ctattaccgc ttggtggcta
    13621 tgtgcgaatg gcaggctggg gtgatgacac aactgagata aaaacaggaa cgcctgctag
    13681 cttaacgctt aatgatcagg gcttggtcaa gcggattaac ctgtctcaga gcaagcttga
    13741 tccgactagc ctgcctatga atgtgactgc ttatgactta gaagataagt tgacgattac
    13801 agggctggtt cttgatgaga tcaagaccta ttcggtagac catgacgcga ccattgtcga
    13861 ggaggacggt acagagatcc ggattgcgcc gcttgatgtt cagtatcaaa acgcaagcat
    13921 tggcggtcgt ttgatcacca attttgcagg acctatgaat aattttattc taggtattgt
    13981 tgtctttatt ttgtttgcct ttgttcaagg tggtgtggct gattatcata gcaaccatat
    14041 tcgtgtggtg gaaaatggcg cagcagccaa ggctggtatt agagacaatg atcagatttt
    14101 agagattaat catcaaaaga ttaatgactg gtatgagttg acgcaggccg ttactgattc
    14161 agcagcagat gttaaggcta agggcaagct agagattacc tatcagacag gtgatcaggt
    14221 taagactata gcactgaagc ctgaaaaaaa aggcgatcag taccttattg gtgtccagta
    14281 cccactaaaa acaagtctga cagacaagct aataggtggc tttgagatgg ctggtaatgg
    14341 tgctctagtg attgtcactg ctctaaagag tttgattacc tcctttagcc tagataaatt
    14401 aggtgggcca gttgccatgt atcagatgtc caatcaggca gcaaagaatg gtttagagtc
    14461 tgtcttgtcc ttgatggcaa tgctctctat caatttaggg atttttaatt tgattccgat
    14521 tcccgcacta gatggtggta agatcctgat gaatgtgatt gaagcacttc gtcgtaagcc
    14581 attaaagcaa gagacagaga cttatattac ccttgcaggt gttgcgatta tggtggtact
    14641 catgattgca gtgacctgga acgatattat gcgagccttt ttccaaggct gatggtctct
    14701 ctcatttaaa ggagagccta aaaggcttaa tgtaacagaa ataacaagag atatagtgtc
    14761 attattgtgg ttctaagacc ttgcaaatgc agcaaaagct tagccaatat agctcatttt
    14821 gtctcttttt tagaaatgaa ttctcaacga aaggaaagag agctgttgac caagctgggc
    14881 taaggcctac agctgaaatc aaaatgctag acctgctatt agtctaaggg cgttttgagc
    14941 tgctctctat agcttatttt aatgaaacaa agtaaaatgc ttatcccaac cctgcgcgaa
    15001 atgccaagtg acgctcaggt aatcagtcat gccctcatgg tgcgtgcggg ctatgtccgt
    15061 caggtatctg ccggtattta tgcctatttg ccattagctc atcgtacaat tgaaaaattc
    15121 aagacgatta tgcggcagga atttgacaaa attggtgctg ttgaaatgct agcacctgcc
    15181 cttttaacag ctgacctctg gcgtgaatca ggccgctatg agacttacgg tgaggacctt
    15241 tacaagctaa aaaaccgcga caaatcagac tttatcttag gtcctaccca tgaagaaacc
    15301 tttactacac tggtgcgtga tgcggttaaa tcctataagc agctgccgct caatctgtat
    15361 cagattcaat ccaaatatcg tgatgaaaag cgtcctcgta atggcctgct tcgcacacgt
    15421 gaatttatca tgaaggacgg ctatagcttt catcaaagct atgatgattt agatgtcacc
    15481 tatgacgcct atcgtcaggc ctatgaggct atttttacca gagcaggctt ggatttcaaa
    15541 ggaattatcg gtgatggtgg tgctatgggt ggtaaggatt cgcaggaatt tatggctatc
    15601 acaccggacc gtactaattt agaccgctgg ctggtcttag acaagtctat tccgtcattg
    15661 gctgacattc cagaggaggt cttggaagag attaaggccg agctggcttc atggctggtt
    15721 tcaggagagg acaccattgc ttattcaagt gaatcaagct atgctgctaa ccttgagatg
    15781 gcaaccagtg agtacaagtc ctcatcaaag gtaacagcct tagatgatct cgtcgagatt
    15841 gagacaccaa attgtaaaac cattgatgaa gtggcggcct ttcttgacgt tgctgagcat
    15901 caggtcatta aaaccctgct ctttatggtg gaccatgagc ctgtgcttgc tttattggtt
    15961 ggaaatgacc agatcaatgc tgtcaaattg aaaaaccacc tcggtgcaga cttcttagag
    16021 ccagctagcg aggaggaggc gcgtgctatc ctaggtgcag gctttggttc acttggtcca
    16081 gttcatttga cagatggtat ccgtattgtg gctgatcgta aggtccaaga ccttgctaat
    16141 gctgtagctg gagccaataa agatggttat cacctgactg gtgtcaatcc aaatcgtgat
    16201 ttccaagcag agtatgctga tattcgtgag gtaaaagagg gagagacctc tccagataga
    16261 catggcgtgc tgcagtttgc cagaggtatt gaaatcggtc atatctttaa gctggggacc
    16321 cgctattctg atagcatggc agctaatatc cttgatgaga atggcagagc agttccgatt
    16381 gtcatgggct gctatggtat tggggttagt cgtatcctat cagcagtcat tgagcagcat
    16441 gctcgtctct ttgtcagcaa gacaccaaag ggtgattatc gctatgcttg ggggattaat
    16501 ttccctaaag agctagctcc gtttgatgtg catttgatta ccgttaatgt caaggatcag
    16561 gaggcgcagg acctgacaga aagagtagag gctagtctga tggccaaggg ctatgatgtc
    16621 ctcactgatg accgcaatga gcgtgtcggc tctaagttct ctgatagtga tttgattggg
    16681 cttccgattc gtgtgacgat tggtaaaaaa gcagctgagg gcattgttga gatcaaaatc
    16741 aaagcaacag gtgacagcat tgaggtgcac gctgatagct tgattgaaac tcttgacatt
    16801 ctcacaaagg acaactaatg atatgaggtc aacgatggtt gatctctttt tgtatgctat
    16861 aatgaaagca tgacaattga ggaattacag cagctggtgc tagcagatca tgagctaatg
    16921 actattctaa gcattataga gaccttgcct ttaaaggatt gttggctggc agcaggtgca
    16981 attcggaacg ctatttggaa tcatttagct tatgggatag gctttgatcc gctgacagat
    17041 gtagatgtgg tcttttttga ccctgagatc tcttacgaag ctgagcagct gctagaagag
    17101 cagcttaagt gtgcttatcc catgtaccaa tgggaggttc gcaatcaagc ctatatggca
    17161 gcacataacc ccaagacgcc tccttatcga tctagtcaag acgctatcac aaagtatccg
    17221 gagcgctgta cagcgattgc tgttagactt gtaggaggac agctagaggt ttttgctccc
    17281 tatggtttag cagacattag tcactttgtc tgtcggccaa caccgcattt tttagaggat
    17341 tcagagcgta tggactgcta taggcagcgc ctagcaaaga aggactggca caagaaatgg
    17401 ccacagctga cctaccacga ctgctaagtc agaggaaaca aagcaggcta ggagctccgt
    17461 acagccaagc aattagtccg ctcccagacc cgttagctac agctctcacc tagtcaaaac
    17521 aagcacatga acagatcatt ggcagatagc cttgcctttg cagatattgt cacaccctat
    17581 ttagctgtac catgtgtctt atgataggcg tgatagtgct gtcagaagcg ccagctgagc
    17641 cagaaaaagc gttaagccta cagcaagggg cttttaacct ttggtatgtt gtcttgtagg
    17701 agaggtcgaa aatgatcact atttatgata aaatagaccc taagaaaatc aggagaaagc
    17761 tatgtcagat ttattcggta aattgatgga acaaattgaa atgccacttg agataagaca
    17821 atcaagtgcc ttttcgtctg ctgatattat cgaggtcaag gtgcattcag tgtctcgtct
    17881 gtgggaattt catttttcct ttgcagaggt tctcccgata gagagctatc gagagctgtc
    17941 agataggctt gtgagaacct ttgaggcagc agatattaag gtaacatttg acatcaaggc
    18001 agagacaatt aattattcgg atcagctgct gcaagcctac tatcaagaag catttgagca
    18061 tgagccctgt aatggggcta gcttcaagtc atctttttct agacttcagg tcaggtatga
    18121 ccatcatcag ctgatcatta tggcacctga ctttgtgaat aatgatcact ttaggaaaaa
    18181 tcatttaccc aatctggcag ctcagtttga gcgctttggc tttgggaggc tagcgattga
    18241 tatggtgtct gatcaggaga tgacagacca tttgacaaag gactttgaga ccaaccgtca
    18301 ggctctggtg gaaaaggctg tacaggataa tatcgcagca cagcaatcat tggaggccat
    18361 gcagccacca gctgaggagg cagcaccaag cccaagcctt gactatagag agcgtatggc
    18421 tcagcgccaa gcaagctttg ataaggcggt cattacacca atgattgagg tggatacaga
    18481 agaaaatcgc attgtttttg aaggaatggt ctttgatgtg gagcgcaaga cgacaagaac
    18541 aggccgccat atcatcaact tcaagatgac agattacacc tcctcctttg ccatgcaaaa
    18601 atgggccaaa gatgacgatg agctcagaaa atttgatctg attgcgaagg gagcttggct
    18661 gcgcgttcag ggaaatatcg aaaacaaccc cttcaccaag agcctaacca tgaatgtgca
    18721 gcaggttaag gcgattgttc accatgagcg taaggatctc atgccagaag ggcaaaagcg
    18781 tgttgaattt catgcacaca ctaatatgtc cacaatggac gctctaccga cggtagaaga
    18841 cctgattgat acagcagcca ggtggggaca tcaggcagta gcgattactg accacgctaa
    18901 tgttcagagc tttccgcatg gctatcatag agcacgcaag gcaggaatca aggcaatctt
    18961 tggcttagag gccaatattg ttgaggataa ggtacctatt tccttcaatc ctgtcgctat
    19021 ggacctgcat gaagccacct atgttgtctt tgacgtggag accaccggcc tttctgccat
    19081 gaacaatgat ttgattcaga tcgcagcttc caaaatgttc aagggaaata tcattgagca
    19141 gtttgatgag tttatcaatc caggccaccc cttatctgct tttacaacag aattgacagg
    19201 gattacagat aatcatttgg taggagctaa gcctatacag caggtgttag aggcatttca
    19261 ggccttttgt cagggcacta tcctagttgc ccacaatgct agctttgacg tgggatttat
    19321 gaatgccaac tacgatcggt atggtttagc aaaaatcagc cagccagtta ttgacaccct
    19381 ggagcttgcc agaaacctgt accctgagta taagcggcat ggcttgggcc ctttgactaa
    19441 gcgctttcag gttagccttg agcaccatca catggccaat tacgatgctg aagcaacagg
    19501 gcgtttgctc tttatcttcc taaaggaagc tagagaaaag catgggatta caaacctgct
    19561 tcagctcaat acagacttag tggcagagga ttcctataag aaagcacgga tcaagcacgc
    19621 cacgatctat gttcaaaatc agctaggtct caaaaacatg tttaagctgg ttagcctttc
    19681 aaatgtgaaa tattttgaag gtgtgcctag aattccaaga accgtccttg atcagcatcg
    19741 tgaaggcttg ctgcttggga cagcctgctc agacggcgag gtctttgacg ctgttttgac
    19801 ccaaggaatt gacgctgctg ttgatctggc caaatactac gattttatcg aaatcatgcc
    19861 gcctgcaatt taccagccct tggtagtccg agagctaatc aaggatcaag caggagttga
    19921 gcagattatt cgcgatttga ttgaggtcgg ccgcagagct gaaaagcctg tcctagctac
    19981 tggaaacgtg cactacattg agccagagga cgccatctat cgtgacatta tcgttcgtag
    20041 tctagggcaa ggtgccctga ttaaccgtac tattggccgc ggagaggctg ccaagcctgt
    20101 cccgctacca gaggctcatt ttagaacaac caatgaaatg cttgatgatt ttgccttttt
    20161 aggtcaggac ttggcctatg aggttgtggt gcaaaatacc caagcccttg ctgatcgaat
    20221 tgaaaaggtg gaggttgtta aggatgatct gtacacccca tatattgata aggcagaaga
    20281 aaccgttgct gagctgactt atcaaaaggc ctttgctatc tatggcaacc cacttccaga
    20341 tatcattgat ctgcgcattg aaaaggagct aacgtccatt ttgggaaacg gctttgcggt
    20401 gatttatcta gcctcacaaa tgctggttaa tcgctctaat gagcgtggtt atctggtagg
    20461 ctcacgtggc tctgttggtt caagctttgt tgcgaccatg attggcatca cagaggtcaa
    20521 tccaatgccg cctcattatg tctgcccaag ctgccagcag tcagagttta tcacagatgg
    20581 ctcggtcggc tctggctatg atttgccaaa caaggcctgt cctagatgtg ggacgctgta
    20641 caaaaaggac ggacaggata ttccttttga aaccttcctt ggctttgatg gtgataaggt
    20701 tccagatatt gatttgaact tctcaggaga tgatcagccc aatgcccact tggacgttcg
    20761 tgatatcttc ggggaagaat acgcctttcg tgcaggtact gttggtactg tcgctgaaaa
    20821 aacagcctat ggctttgtca agggctatga gagagattat ggcaagtttt acccagatgc
    20881 agaggttgat cgtctagctg ctggtgctgc tggtgttaag cggacgactg gtcagcaccc
    20941 tggtgggatc gttgttatcc ctaactatat ggacgtttat gattttacac ctgtgcagtt
    21001 tccggcagat gatgtgacag cctcatggca gacgacccac tttaatttcc atgatattga
    21061 tgaaaatgtc ctaaagctcg atgtactcgg tcatgatgat cccaccatga ttcgtaagct
    21121 gcaggattta tcaggtattg atccgattac tattccagca gatgatcctg acgtgatggc
    21181 acttttttct ggaacagagg tgctcggagt gactcctgaa caaattggaa caccaacagg
    21241 tatgcttggg atcccagagt ttggaacgaa ctttgttcgt ggcatggtga atgagaccca
    21301 cccaacgacc tttgcagaat tgctgcagct atcaggtcta tcgcatggaa cggacgtctg
    21361 gctgggtaat gctcaggatc tgatcaaaga aggcattgcc accctaaaaa cagttatcgg
    21421 ttgtcgagat gacatcatgg tttaccttat gcatgctggt ctagagccta agatggcctt
    21481 taccatcatg gagcgtgtgc gtaaggggct ctggctaaag atttccgagg aggagcgcag
    21541 ctcctatatc aaggccatgc ggcaaaacaa cgtcccagac tggtacatcg aatcctgtgg
    21601 taaaatcaag tacatgttcc ccaaggctca cgctgccgcc tatgttttga tggcattgcg
    21661 agtggcttat ttcaaggttc atcaccccat catgtattac tgtgcttatt tctctattcg
    21721 tgccaaggcc tttgagctca aaaccatgag tggtgggcta gctgctgtca aggctcgcat
    21781 ggaggacatc agcaacaagc gcaagcgcaa tgaagcctca aacgttgaaa atgacctgtt
    21841 taccacttta gaaattgtca atgaaatgct tgagagaggg tttaagtttg gcaagctaga
    21901 cctttacaag agcgaggcaa ctgagtttca aattgaaggg gataccctaa ttccaccttt
    21961 tattgcctta gaaggcttgg gagaaaacgt tgctagacaa atcgtcaagg ctcgccaaga
    22021 tggtgaattt ctatcaaaaa tggaattacg caagcgtggt ggtgcttctg ccactctagt
    22081 tgataagatg gacgagctgg gcattttagg aaatatgcca gatgacaatc agctgagtct
    22141 atttgatgac tttttctaag attgcacagc cctaatattg tctatgttag cttgtcatac
    22201 agtgaagagc agggcaggaa ggcttcctgt cctctttttg tcaatacgca aagaaagccc
    22261 aaaaaagaac gaggaaaagc atgaatgaat tagacaaaaa tcctgcctta aaggcaatgg
    22321 ttgtttttag aaaagcacag cgtaccttag atgctcaaag ctccgccttt tttcaaaagg
    22381 ccaatctgac tcctacccaa tttagcgtct tagaggtgct ttattccaaa ggaagcatga
    22441 gaattaacaa gctcatcggt tctctcttgg caacctctgg caatatgacc gtagtgctga
    22501 aaaatatgga gagaaatggc tggatcagcc gctgccaaga tgctaaagat aagcgtgcct
    22561 gcttggtaca gctaacgcca gagggcaaag ccttgattga gactatccta cctgagcata
    22621 tcaaacgtgt tgaagccctt ttttcagtgc tgacagagac tgagcaaaaa caattgatta
    22681 cgcttttaaa gaaatttaaa gaactctaag caaatggctt tacaggatct cccaagtagg
    22741 atataatcac tacatagtac aaaaagatac taactagtca taataagtca tcaagacagc
    22801 agatggctag ttaccagata atcaatggga gacaaagcat gaaacaaatt ttaatcatta
    22861 atggttcatt acggacaggt tcatttaatc atcagcttgc tcaagcggct gagcagctac
    22921 ttgaaggcaa ggcagctgta tcttacttgg actgggaaca ggtacctatg tttagtcagg
    22981 atttagaagc aagcacccct gagtcagtgg caggcgtacg agaagccatt caagcagcag
    23041 atgctatctg gattttttca cctgtctata attttgcaat cccgggctct atcaaaaacc
    23101 tattagactg ggtatcacgc gcccttgatt tgtcagaccc atcaggacca tcagcaatca
    23161 atggtaaggt agttaccgta tcatctgttg ctaatggtgg gcacgagcag ctatttgcgc
    23221 aataccagga cctgctgccc tttatccgta cgacagtagt tggtaacttt accaaagccg
    23281 ctgtcaatcc agaagcatgg gcgacaggtg ttcttgatat ttctgaggaa acaaggcaaa
    23341 gccttgcagc acaggcagaa gcccttcttg aagccattca ctaagactct ctgagcatta
    23401 aacagataaa gctgcagcta ggatcaaaaa gcagctagac acataaaaag agcttaaacc
    23461 agaaatgtac ggcactccaa aagctagaca aaaactctag cgattggggt acaggtcaaa
    23521 acggttttaa gctctttttt agacttattt tatagtagta acttaattaa gaattagcat
    23581 accctcttta gcctcaaagg ggtttttcgc attaatacgg tcatagaata agacaccatt
    23641 aatatgatca atctcatgct gaaccacgat agcattgtag ccctttagct taatgcggtg
    23701 cttttcattg tgcttatcgt aatattccac tgtcacacgc gcatgacgga cgacatagcc
    23761 ttccaccaca cgatcaacag acaaacaccc ctcaccgtca gcaagagcag cgtcttgaac
    23821 agaatgagac acaattttag gattatagag cacttcctcc atgctgtaag cctccttagg
    23881 tggattgccc tcgctgtctt caggatttgg aaccagaaca gcgatgatac gctttgacac
    23941 atcaatctga ggtgctgcta gaccaactcc tgctcgaagc cctaattttt ctcccatgac
    24001 agggtcttga gaatgcttta aaaattgcat cattttttca cctaaaatga tgtcatcatc
    24061 actaagagga aactcgacct ccttagccac agcacgaagc gtaggattgc cttcgcggat
    24121 aatatcattc atatcaatga gatgctgtgc tttaattaat ttatcttgtg cagacatttt
    24181 gcctcccttt ttttatattt gataatggct ttactatatc acaaaatcct tatttttaaa
    24241 agataaggca ggccagtgat gacgata
//
LOCUS       DARYXS010000025        23453 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.025, whole genome shotgun sequence.
ACCESSION   DARYXS010000025 DARYXS010000000
VERSION     DARYXS010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23453
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.025"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            89..472
                     /locus_tag="TV193_000787"
     CDS             89..472
                     /locus_tag="TV193_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1513006.1"
                     /translation="MDEKKLFENFQLTFGRMISPFEIEDIQKWIHQDNMPIDVVNLAL
                     REAVENNKINWKYINKILVEWHKAGDTTIEKVKERLQRFEDSKEQRHATISNVPSWSN
                     PDYQGPTYDDLKVNPSEVSDGAGDF"
     gene            453..686
                     /locus_tag="TV193_000788"
     CDS             453..686
                     /locus_tag="TV193_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513007.1"
                     /translation="MAQEIFDGFNALINKMYGRQSSIETFNRFVEYCQKRREENGVEP
                     VLNPINLFAFGVGITTEEANKLRIKRYKQENGL"
     gene            683..823
                     /locus_tag="TV193_000789"
     CDS             683..823
                     /locus_tag="TV193_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513008.1"
                     /translation="MTKQYRETLIWHRASHKEREKLLDFGLVDKSQYMTLLRQLRKKY
                     AI"
     gene            832..1038
                     /locus_tag="TV193_000790"
     CDS             832..1038
                     /locus_tag="TV193_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513009.1"
                     /translation="MTPEQVEKAKIRAKRELETFSIYLDQAIVEYGSTLSPQEVFLAA
                     GFAYLGAGQTDIHAAIEGLYEQIQ"
     gene            1173..1901
                     /locus_tag="TV193_000791"
                     /pseudo
     CDS             1173..1901
                     /locus_tag="TV193_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017827951.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
     gene            2078..3289
                     /locus_tag="TV193_000792"
     CDS             2078..3289
                     /locus_tag="TV193_000792"
                     /inference="COORDINATES: protein motif:HMM:NF018751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEL1513010.1"
                     /translation="MSENLTLFENLNDIKPAEPAELSFDFEFTPAEIKIKGKEKLEEI
                     LAAYAKKYDGYTVTAETFEDDAKVRAKLNTLQKDINNSVKTKLAEYNNPLDDVKQWVN
                     SIIEPIKKITKTIDEGVKHFEEIERQKRANTIKETFEAAIAETGADIDIRLFESNFDD
                     MSAKGYFMADNVRVNTATKKAINKLVAEEVAKKQEHEQALIQISEAAAKADFGPAIYI
                     KRFENGAQLADILQAIADDKLLADKVREEEKRKAELSKRVEEMTALAQREGLQPGKYV
                     KLLEDGKSALVVFETLMDDSKKMQAKIAQKNAEAHQQQIEQTEYMSEASNSGVNELET
                     DKVINNIIKQENALEAKIEPNKSVTKWQGDFKITFPDSETAKLFGGQGGLYEKHGVIV
                     EKLGEWVKIND"
     gene            3282..4118
                     /locus_tag="TV193_000793"
     CDS             3282..4118
                     /locus_tag="TV193_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL1513011.1"
                     /translation="MTKLTEENYYQDREWLSNSRFKAFLDCEAKALAVENNEWEDTRD
                     ETPLLVGNYLHSYFESPEAHEKFKAENGAKMISSRGVTKGELKKEYKVAQNMIETLET
                     DEIFNLMYHGQSGDNVLKEMIIYGEILGIKVKGKVDSINLTKGYFCDLKTMKSIHSDE
                     WSNDLRKRVPGVAANIIGFKYHIQMGLYQELLRQMTGKTLQPLIIAISKENVPDKELI
                     ELGQTWLDEGLQLFENNVEHVHEVIIGKAEAKSCGRCDYCRSQKKLNRVVDLDDLIAG
                     IF"
     gene            4303..4644
                     /locus_tag="TV193_000794"
     CDS             4303..4644
                     /locus_tag="TV193_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513012.1"
                     /translation="MEQIKITGTDTILILDRVDRAFVIEGNLAERWRFTSKFIKIDDE
                     LSLDEDGELFEIVYDLMLEAKPHNVINLTSSYFAKEHKKDTDEIIKVFAFIEDNKKNI
                     FETLGIRGVLE"
     gene            4641..5153
                     /locus_tag="TV193_000795"
     CDS             4641..5153
                     /locus_tag="TV193_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513013.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLIQSGVLKHKSDSYFERGRY
                     MASKLRLIQSRALKKYDCSFSTIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVV
                     FINVSTWRKHWKFSYKDRSKKAMKAQSKAKAAENFGKIVKDDEADAVLIGAYYVNQGY
                     LDGLETHDYY"
     gene            5375..5602
                     /locus_tag="TV193_000796"
     CDS             5375..5602
                     /locus_tag="TV193_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513014.1"
                     /translation="MTKNDFLTGFVLILLAACIFAAGFVIGSDCSSEHYEQQMTGLRM
                     QLVNTQQQLKRASEDRARRTKRIADLTGNGG"
     gene            5606..6028
                     /locus_tag="TV193_000797"
     CDS             5606..6028
                     /locus_tag="TV193_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1513015.1"
                     /translation="MIDEIELDLQKPEIPQFVADYIDDMHKNARTLRYAFKYMESNIK
                     MHKWCVFERQETFVNAFLYGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFS
                     EIIDTDFYSREDVRLTESEIRKDFDWAWREGFAKEVTE"
     gene            6196..6426
                     /locus_tag="TV193_000798"
     CDS             6196..6426
                     /locus_tag="TV193_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003077369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513016.1"
                     /translation="MAYLREERETVIHYDELDDCWTFETNVRRHITKIEKRIELYEIL
                     SEEFDDRGRRIYICAKMKTGTVSPFAKPPRRK"
     gene            6803..7237
                     /locus_tag="TV193_000799"
     CDS             6803..7237
                     /locus_tag="TV193_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL1513017.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVHSKPVERLALNRVSAEQELDAIEQAVSMILEPERRRILYDKYLSPYKKAD
                     KVIYTELCMSESFYYDTLDIALLAFAELYREGSLIVEQGVFS"
     gene            7775..7849
                     /locus_tag="TV193_000800"
     tRNA            7775..7849
                     /locus_tag="TV193_000800"
                     /product="tRNA-OTHER"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
     gene            8008..8499
                     /locus_tag="TV193_000801"
     CDS             8008..8499
                     /locus_tag="TV193_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1513018.1"
                     /translation="MAKLTIKQQKFIDEYIICGNATEAALKAGYSKKTAGQIGEQNLK
                     KLEIKSAINERLKQLESSKIASAIEILQVLTAVLRQDLTEEVVTLNPVTGEYVTMQKK
                     PSIAEVIKAAGELLKRYPIQEQIEKIKQENELLRLKIETVKGAKPDTHLMEKLLEVIE
                     DGG"
     gene            8534..9787
                     /locus_tag="TV193_000802"
     CDS             8534..9787
                     /locus_tag="TV193_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1513019.1"
                     /translation="MRRPFNYELEVNEGTPRSGKTTAGHFRYARYLIESEDENHLVTA
                     YNQEQAYRLFIDGDGTGLMHIFDGNCEIKHDERGDHLLVTTPKGNKRVYYKGGGKVNS
                     VGAITGMSLGSVVFCEINLLHMDFIQECFRRTWAAKLRYHLADLNPPAPQHPVIKDVF
                     DVQNTRWTHWTMDDNPILTAERKQNIINSLKKNPYLYKRDVLGQRVMPQGVIYGLFDM
                     EKNVLDTLIGEPVEMYFCADGGQSDATSMSCNIVTRVRDNGKISFRLNRTAHYYHSGA
                     DTGQVKAMSTYARELKAFIDWCVKKYQLRYSDVFIDPACKALREELHAIGILTTGAPN
                     NAHDVNSKAKGIEVGIERGQTLISDGDFYLVNHKEEKYDHYHFLKELGLYSRDDKGKP
                     IDANNHSMDEFRYSVNVFVGRYKMK"
     gene            9797..11296
                     /locus_tag="TV193_000803"
     CDS             9797..11296
                     /locus_tag="TV193_000803"
                     /inference="COORDINATES: protein motif:HMM:TIGR01542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1513020.1"
                     /translation="MFRNLWTKIKGVMQKMGLIKGLKDLNLHREIELSDKHYDSIQIW
                     KELYQGYHDKIHDYYEKSILDGRKKKKRLTLNMPKVVTSELATLIFNEKCEINIGSEN
                     ESLTKLITETLEKNNFTQEFQRFLEYSFALGGMAIKAYLKKDGTIGLNFVQADSFIPI
                     SWDNAGISEAVFVDTQHRGKYKYTHLEWHTWESELYVVAHELFRTDKSNDDVGIRVPI
                     TEIYPDLKSQVVIEKLSRPLFVYLKPNSANNIDLSSPLGISIYHNSFDTLRAIDIAYD
                     SFEREFRLGRKRILVPATAIRTVVDSEGNFHRYFDATDETYEAFHTGEDSKIQDIKDI
                     SVELRVDEHIAAINALLNLLSMQIGFSPGSFSFDGVSGVKTATEVISENSKTFRTKQS
                     HETMVEATLKNLVAIIVDFGDLYGLIEGESKYNVTVTFDDSIAQDRTQDAQYYIGLVA
                     AGLISKKKAMMKLFNLSEEDAELEIQTIHEESRTTNDMSIDLFGLDGDA"
     gene            11296..12906
                     /locus_tag="TV193_000804"
     CDS             11296..12906
                     /locus_tag="TV193_000804"
                     /inference="COORDINATES: protein motif:HMM:NF017919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513021.1"
                     /translation="MDYDTHIQLSFDLIELYSDVERELLTSIGRRFAKHYDEMVAGDI
                     MDWQIRQLLEVGELRKEHIEIMRKSARVSRERMIEMLTEAGYTSAGRYEDFFKEAYVK
                     GLIKLNPSAADNSMRLLRVLNTYINQAEDTLNLVNTTMLQSGQDTFLDTVNQVVAYVS
                     TGIKTPQVAMRDALKNAGQKGLTVFRAKNGAQWSTETYLNMITRTMNSNISNAMEDER
                     RHEYGVDYIEVSSHAGARPRCAPYQGRIYYDGVGDDPLEKYPHFSETSYGEAAGLFGV
                     NCGHHKYPYVPGMSKQTFFPYSKSENDKTYAESQVQRKLEREVKQLKRERAILTAAKD
                     KEGAKLASQRLENKWQELRQFTAQTGRTRRYDREKSLNTILSEDKKKAIVKDNLKIRD
                     EYRAIKKAIPEVAPKNLETYYDMRYNGGKIYEDLVRDYKDYIRWSKAEFPTKKSFEGH
                     IDSHLKEFPGLTGKQYQKKAADLLSRPITDNILGYDTDSRRVRYDLENNIFALGRVKQ
                     GTITTMLKPKEGVDYFDNDWKREFDNLK"
     gene            12872..13093
                     /locus_tag="TV193_000805"
     CDS             12872..13093
                     /locus_tag="TV193_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513022.1"
                     /translation="MTGKESLIILNDLEYVHCPVCGTLTEVYDICDTCKWQNTGETNI
                     DGGPNYITLEEARRRWANGEPLRNFFKDQ"
     gene            13145..13429
                     /locus_tag="TV193_000806"
     CDS             13145..13429
                     /locus_tag="TV193_000806"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513023.1"
                     /translation="MNKRIEKKRRTQMMLDRILRIVELMSQATDDNFAILEKRLEKAE
                     KRNEELMEIILVNVKEVNNRFDELEICQKIVEDDVAELKKAKKKGWFSRK"
     gene            13515..13754
                     /locus_tag="TV193_000807"
     CDS             13515..13754
                     /locus_tag="TV193_000807"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513024.1"
                     /translation="MAVIIVQTRGGDIEVPTPLPAMQANKAIQSQLFDKELTFLCVDN
                     HAFAKTEVLHVLVETEEDEELPQSKHKEEETCYMD"
     gene            13739..14341
                     /locus_tag="TV193_000808"
     CDS             13739..14341
                     /locus_tag="TV193_000808"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513025.1"
                     /translation="MLHGLKHRLFKLAPDTGAGGGAEVTSETNAEAGRVEQTVSQQQA
                     DPVDTEAIKNQAINEVLSQLGVSSVEDAKANLASWNEYQEGQKTEFQKIQDSLTVANN
                     SLAERDTMIASLQAQLAAAQMGVPAENTSDVITLANSLVHDKTDINAAITTVLEKYPH
                     FKGGDADVADKPNFVTQTQSQTETTEDAFFKALGLTIKED"
     gene            14343..15215
                     /locus_tag="TV193_000809"
     CDS             14343..15215
                     /locus_tag="TV193_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513026.1"
                     /translation="MSINYITKHEGIFEKKLMQGALTSNLETPKVNWLGAKSFELPTI
                     SVTGYKAHTRSKGYNAGTVSNDKNTYTLGFDRDVEFFVDKADVDETNQELSMANISNT
                     FITEHATPEVDAYRFSKIATNAIDNSHFKQEDDYSTTNVYERLKAAILPIRKYGAGNI
                     IIYVSSEIMDFLERSKDFTRSIATTSPQGIDTRVTSLDGVQLIEVWDDARFKTKFDFT
                     TGFVKDGSGKDINFLIVAKPAVIAKAKFNSIYLFAPGQHTEGDGYLYQNRLYHDLFVL
                     KSKQDGVYVSHKSA"
     gene            15226..15474
                     /locus_tag="TV193_000810"
     CDS             15226..15474
                     /locus_tag="TV193_000810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513027.1"
                     /translation="MKTYEKDNQVYKVQEGSELEIQLIADGFKEIIEANEKETDITKM
                     KLDKLKAYAENEGIIIPEDIKKKEDVLAFIKEQQQRGE"
     gene            15477..15863
                     /locus_tag="TV193_000811"
     CDS             15477..15863
                     /locus_tag="TV193_000811"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513028.1"
                     /translation="MLTFDFYNKGYCGSQLNEEKFGELSKRAERKILALIGLKKEQVK
                     NLPLDILEAVKMAVCAQIEYLNAIGVESAIGVTSVTQAKVGNFSYTDGKKATVSASVG
                     SVGVSPDVLDYLLPSGLLYKGVNTRW"
     gene            15857..16201
                     /locus_tag="TV193_000812"
     CDS             15857..16201
                     /locus_tag="TV193_000812"
                     /inference="COORDINATES: protein motif:HMM:NF022130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513029.1"
                     /translation="MVKEVKPIPKELLVDTVTYLAVGNKDSWGAETVVSTELSQVLVQ
                     PRSSIQRGQQNESNSYELLLFFDCVNSLPVDHQFKVDDKISYLGKEYRIASVEVLKAF
                     DQSPHHYEVMLE"
     gene            16198..16551
                     /locus_tag="TV193_000813"
     CDS             16198..16551
                     /locus_tag="TV193_000813"
                     /inference="COORDINATES: protein motif:HMM:NF022564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513030.1"
                     /translation="MIGFKVEVIFNASKLIAKSEASAKTARFALSGQIKKDSDKYIPA
                     REWNLRDSGRVTERSVSWHTPYARRLYYNPQYNFSKDKNPNAQGKWFEVAKANHAEHW
                     YELTKKAYGAEFRGD"
     gene            16554..16922
                     /locus_tag="TV193_000814"
     CDS             16554..16922
                     /locus_tag="TV193_000814"
                     /inference="COORDINATES: protein motif:HMM:NF024103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513031.1"
                     /translation="MTFIDFLLRKVQEVSGAEPVLGIMGNSDKVAIIPMAGNFDNRAL
                     DESKIRIFTFQVLAKSKKQQEAFLTTENLVNGLDGLSNEPFTGGYLIKLECTTTTNFV
                     EKDSDKNYLYTALFRAELGG"
     gene            16926..17423
                     /locus_tag="TV193_000815"
     CDS             16926..17423
                     /locus_tag="TV193_000815"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513032.1"
                     /translation="MAADKPTFYLQSEHKLEISEDGKTWMRLAGGISELEPDGNEEVS
                     QDAYLDGSESDVTGGQLVLALTGHRLVGDKAQDWIYARQFRYGGKRRGFTRWTLPGGK
                     TQFTFASTFANIKGPSGAANGKGEIEFEIHSNETLVPNKVVVEVTKTNKELASEALGL
                     ERQER"
     gene            17443..17850
                     /locus_tag="TV193_000816"
     CDS             17443..17850
                     /locus_tag="TV193_000816"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513033.1"
                     /translation="MVRQFEFKKTVEEIEIAGEIYLLPLDDDNLLRIQRDFISYGKEI
                     EELQKVEVEKGDPDDLADNHKQQLLVMKKVIESPFGEGSFEKLYEASGHSLMNMVDLL
                     DYLVELVAEKVEQNKARATKAKEKYYSSKRKKK"
     gene            17858..18475
                     /locus_tag="TV193_000817"
     CDS             17858..18475
                     /locus_tag="TV193_000817"
                     /inference="COORDINATES: protein motif:HMM:NF018553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513034.1"
                     /translation="MKLTETYEVLADAFEFGGHIVTVDLAFDVVLRVMELLADAEVND
                     YAKIVWTLDMLLPYFDRTELSFDEEFEIFEYILKTFIYEQEDGEDDSLGGMSQTKTMH
                     FEKDAELIFASFFQSYHLDLFEQQGKLHWRKFMSLLMNLHKDTPFKEVVSYRVMKVPN
                     KDEASEEYIKHVKKMKRIYSLEDESEHQALNDDKLSALAARFGGE"
     gene            18476..20923
                     /locus_tag="TV193_000818"
     CDS             18476..20923
                     /locus_tag="TV193_000818"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1513035.1"
                     /translation="MADGSVIIDTLLKTEKFNQGVGKLQGKLAGLGSKLTSIGTGLTL
                     GLTAPIVGIGAASLSTFTTFESQMNRVKAISGATASEFRKLEDQAIKLGASSVFSATE
                     VAQAQEMMASAGFKVVDILKAMPGVMSLAAVSGGDMALASEAAATAVNMFGLEAKDAA
                     HVADVFAQAAADTNAEVGDMAEALKYAGPVAGALGISLEETAAAIGIMSNAGIKGSQA
                     GTTLRTSLSRLTDPTKKMRGIMSELGLEFFDVNGKMKSLSGITKELQTKMGDLTDSQK
                     SAAISTLFGKEAMSGMLALVNSAPGALDKQTQALINSNGAAKEMADTMNSGVKGSIEE
                     LKGSLETAGISIGKILAPALTSVIGAITSLVNWFNNLSPTMQNVVVVLGSLLAAIGPV
                     VLIIGVVTTQIAAFQQGVGLVFNAVKGLQAAFAFLTSPIGLVIVAIGALIAVFVYLWN
                     TNEQFRTKIIEIWTAISNFLQPIIQFIGNFIRETWTQLATFWNENQATIMTIAQTTWS
                     FIQTIFTTAIEMIKLAVSVFLGLLQSTWSVTFNSLKVIAQVAWAFISNVFKGSLGSIL
                     AVASAIFEQIKSTIDLAMKIIQNIIKIILSAIEGDWDGVLEGIKGIVSAFGDFIQSTF
                     SNMMDTAKRLVGAGIDTVKGIFDSLWNIDLFGAGQAIINGFLNGLRSMWGAVTDFVGG
                     IASWIAANKGPISYDRVLLKPHGKAIMDGLGNSMKTNFKDIQKDVSGMADDLTRSFQI
                     KRFNGFLPEKYTTKLDELKKYAQATLGGMILAPNMAVQPTVVVNISNEADSDIIRQKV
                     NAKNAQDAIINQLFKKG"
     gene            20927..21688
                     /locus_tag="TV193_000819"
     CDS             20927..21688
                     /locus_tag="TV193_000819"
                     /inference="COORDINATES: protein motif:HMM:NF017520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1513036.1"
                     /translation="MFSIEFLDGERLSADERGWKVKEMSSSGLEQNVVSESPKMRSGR
                     LVYGLYHGIKTYQLVFTKIIKDTLDYSRLVDEVNYYFLRDEPYYLYRDFRKKADRVDL
                     PKKRAKVFTKSIDHQKNGLKVEFTAKLESYELPYEEDTEVQRVTWTATHSWHNKGGHR
                     LDPRYCPMKMTITVSGSGAELKVLFNGQPYFWYKKSVKQGDIFIIDGTDVEKNRYNCF
                     EDCHKQTSFLKTGNNRIDIQGASCEALFEYRLLYL"
     gene            21699..>23453
                     /locus_tag="TV193_000820"
     CDS             21699..>23453
                     /locus_tag="TV193_000820"
                     /inference="COORDINATES: protein motif:HMM:NF018329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1513037.1"
                     /translation="MQVKTKQGVFYVNADYTVVEKQGDYPKLTCTIPIKGNETWIADC
                     QELDRLYPAGEQDEFIIINPIKVTKGSSYDLEITAIGAFHFEFVKARLYEELPERMYT
                     LDYLLDLLFKDSRFSYKLQGDYSTRRFSGFGDDNKLTLFHHLMERFQTEFKVVGKVVL
                     VNTKVGKDTGFQFRYLRNIKDTKYSVDVTNLMTYVKGYGAWFDENDHSKGRLIVDYES
                     PLSKEYGKLDGKPVVDERMSLKESLIKKCKLAVDRSVSVSLTTTLVSLKQQDYQGAAR
                     IGDSIWFIDERISIEKKIRFSVVTTYYNAYDDILKQDVTLGDKDTYSRYQSLENSSQT
                     ETNDFQKAMSSKLAEVQDDVKKTHILVSGTTRIFFSTEFPQDNPKGTIKEDDILYRNH
                     DGTTLMYRWNGVQWELVPLVNDPDRWREELEKQISEAVEKLKQEQKVINQRTDKELEE
                     FRDTLKNLSLPEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTD
                     GKTRYNKNLLVGDPNRTKTYDQDYIELEANDGGFRRGETYTISFSQTCELLKKVAITL
                     TQANNKGVKLVLTPTKAKM"
BASE COUNT         7875 a         4056 c         5292 g         6230 t
ORIGIN      
        1 taactaataa atactaacac taaataaata ctaaataata ataaatacta acaaacaata
       61 agcatcatca tcaacagcag gaggagctat ggacgaaaaa aagctttttg aaaattttca
      121 actaactttc ggaagaatga tatcgccatt tgaaatagaa gatattcaaa agtggattca
      181 ccaggataat atgccgattg atgttgttaa ccttgcttta agagaagcgg tagaaaacaa
      241 caagatcaat tggaagtata tcaacaaaat tttggtggag tggcataaag ctggagatac
      301 gacgattgag aaggtcaaag agaggttgca gagatttgag gatagcaaag aacaacgaca
      361 tgcaactatc tcaaatgttc ctagctggtc aaatccagac taccaaggcc cgacatacga
      421 tgatttaaaa gtaaatccaa gcgaggtgtc agatggcgca ggagattttt gatggattta
      481 atgccttaat caataaaatg tatggcagac aatctagcat agagaccttt aaccgatttg
      541 tcgagtattg tcaaaaaagg agagaggaaa acggggttga gcctgtatta aatccgatca
      601 atctttttgc attcggcgtt ggaatcacaa cggaagaagc taataaatta agaataaaac
      661 gctacaaaca ggagaatgga ttatgacaaa acaatatcga gagacactta tctggcatcg
      721 ggcaagtcac aaagagcgtg agaagctgct tgatttcggg ctagttgata aatcacagta
      781 catgacacta ttacgccaat tgcgcaagaa atatgcgatt taggaggaaa tatgacacca
      841 gaacaagtgg aaaaagcaaa aatcagagct aaacgagaac ttgaaacgtt tagcatctac
      901 cttgaccagg cgattgtcga atacggaagt acgctaagtc cacaagaagt ctttttagcg
      961 gcagggtttg cctaccttgg tgcaggtcag actgacatac atgcggccat cgaggggtta
     1021 tatgagcaaa tccaatgatt ttaattttag cgatgactgg gaaagcaact atttcgaggt
     1081 ccaagctttg ctagggcaag agatagacaa gctccaaaac agggtcatag cgctaagcca
     1141 ggaaaacaat agattaaaag cgaggaaatg aaatggcaag tgaaattgta acaattcaaa
     1201 aagatatcac tgatatcgtt aattcaaaaa ttagtatgct tcagaacgaa ggtcttgtaa
     1261 tagcgccaaa ctatgctcca gcaaatgctt tgaagtcagc attctttaaa attttaaaaa
     1321 ccaaagacag aaataagagg cctgctcttg aagcctgcac aaaggactca attgcgaact
     1381 cgctccttga aatggtcacc caaggattat cacctgcaaa aaatcaatgc tattttatcg
     1441 tttacgggaa tgagctccaa ctgcaaagat catatttcgg aacaatggca gttttattgc
     1501 agcagaaaaa aattaaatca attaagtcag aagttattta tgaaggtgac gattttgagc
     1561 ttgaaattgt agatggtgaa aagaaattca aaaagcatga tactcattgg aaaaatcaag
     1621 acaatccaat tgaaggggct tattgcatta ttgaggatat agatggtaac actaagctaa
     1681 cactgatgac aaaaaaagag attgataaag cgtggtctaa gacaaagact ggtggaggga
     1741 cacaaaaaga attccctcag gaaatggcca aaaaaacagt tatcaacaga gctgctaagt
     1801 tttttatcaa tatcagtgat gacagtgaca ttttggcaga ttctattaac aagaccaccg
     1861 cagatgaata tattgacgat cgtcaagtaa aagatgtaac ggaaacacag tcacctgcac
     1921 agacactact cgataacatg aagcatgacg aggaaatgag caaaatcgaa acgatgcaaa
     1981 atgaacaatt gatgcatgat ccagaaacag gagaaatcat tgatgcagag gttgttgagg
     2041 cggacctaaa ggaatctgat atggaggagc cattctaatg agcgaaaatt taacactttt
     2101 tgaaaattta aatgacatta aaccagccga acccgctgag ctgagttttg attttgagtt
     2161 tactccagcc gaaatcaaaa tcaaagggaa agagaagctc gaagagattt tagcagccta
     2221 cgctaaaaaa tacgatggct acacagtgac agccgaaacc tttgaagacg atgcaaaggt
     2281 tagagcaaaa ctcaatactt tgcagaaaga tattaataac tctgtaaaaa caaaactcgc
     2341 agaatacaat aaccctcttg atgatgttaa gcagtgggtt aactcaatta ttgagccaat
     2401 taaaaaaatt acaaaaacga ttgatgaggg tgttaaacac tttgaagaaa tcgaacgtca
     2461 gaagcgtgca aatacaatca aagaaacctt tgaggctgct attgctgaaa caggtgctga
     2521 tattgatatc cgcttgttcg aatctaactt tgacgatatg tcggctaaag gatattttat
     2581 ggctgacaac gtccgcgtca ataccgctac caaaaaggcc attaacaaat tggttgctga
     2641 agaagtagca aaaaaacagg aacatgagca ggcgcttatc caaatttcag aagctgctgc
     2701 caaagcggat tttggaccag ctatctatat caaacgattt gaaaatggcg cacaactggc
     2761 agatatctta caagcaatcg ctgacgataa actgcttgct gacaaggtgc gcgaagaaga
     2821 aaaacgcaaa gcagaactat ctaagcgagt agaagaaatg acagccctgg cacaacgtga
     2881 agggttgcaa ccaggcaaat atgtaaaatt gcttgaagat ggcaagtctg ctttagtcgt
     2941 ttttgaaact ctgatggacg attctaaaaa aatgcaggcc aagatagcac aaaaaaacgc
     3001 agaagcgcat cagcaacaaa tagaacagac cgaatatatg tctgaggcct caaattcggg
     3061 ggtaaacgag cttgaaacag acaaggtgat aaataatatc atcaaacaag aaaatgcctt
     3121 agaagccaaa atagaaccga ataagagcgt cacaaaatgg caaggtgatt ttaaaataac
     3181 tttcccggat tcagaaacag ctaaactatt tggcgggcaa ggcggattat acgaaaagca
     3241 tggcgtgatt gttgaaaaat taggtgaatg ggtgaagatt aatgactaaa ttaaccgaag
     3301 aaaattatta tcaagaccga gaatggttgt ctaactcaag atttaaggct ttccttgatt
     3361 gtgaggctaa agctttagct gtcgaaaaca acgagtggga agataccaga gatgagacac
     3421 cgcttttggt tggtaactac cttcacagct atttcgaaag tcctgaagct catgagaaat
     3481 tcaaagccga gaatggagct aagatgattt ccagtcgtgg agttacaaaa ggggaactca
     3541 aaaaagagta caaagtagcg caaaacatga ttgaaacgct agaaactgat gagatattta
     3601 atctcatgta ccatggccaa tctggtgata atgttttgaa agaaatgatc atatacgggg
     3661 aaatcttagg cataaaagtt aaaggaaaag ttgattcaat caatttaaca aaaggttatt
     3721 tttgtgactt aaaaacgatg aaaagcatac acagcgacga atggagtaat gacttgcgta
     3781 agcgtgtacc tggtgtagca gctaacatta tcgggtttaa ataccatatc cagatggggc
     3841 tctatcaaga attactcaga cagatgactg gaaaaacgct tcaaccgcta atcattgcaa
     3901 tcagtaaaga gaatgtacca gataaggaac tcatcgaact tggccaaacg tggctagatg
     3961 aagggttgca actttttgaa aacaatgtgg agcatgtgca cgaagtcatc attggtaaag
     4021 ctgaagctaa gtcgtgtgga cgttgtgatt attgtcgaag tcagaaaaag cttaataggg
     4081 tggttgatct cgatgatttg attgcaggaa ttttttagga gatcttattg tattgcaaag
     4141 tgatgctcgg cctttgcagc aacaaatatt ttccgagcga gaaaggaaaa ttgcaatatc
     4201 gtcaagttaa caggattgat gatataaaga gttgctacac tcgtccttgc taatgctcac
     4261 acacaatttt agggcgagtg tggattttaa aaaggtgaaa atatggaaca aatcaaaatt
     4321 acaggaactg acacaatatt aattttagat agagtagata gggcctttgt cattgagggt
     4381 aatctagctg aaagatggcg ttttactagc aagtttataa agattgacga tgagctatcg
     4441 ctggacgagg acggcgaatt gtttgagata gtttatgact taatgctaga agcaaaacct
     4501 cacaacgtga ttaatctaac atcatcatat tttgctaaag aacataagaa agacacagat
     4561 gaaatcataa aagtatttgc ttttatcgaa gataacaaga agaatatttt tgaaaccctt
     4621 ggcattcgcg gggtgcttga atgagcaatc tagtattatc gctagacatc tcaacatctg
     4681 gtacaggttg ggccttattt aaaggctcag accttatcca gagcggtgtc ttaaaacata
     4741 agagcgactc ttattttgaa cgtggacgct atatggctag caaattaagg ttgatccagt
     4801 cacgagcatt aaaaaaatac gattgctcct ttagcacaat cgcagtcgaa aaaaactcgg
     4861 ttatgggtcc aaatcaacaa tccatgctta aaatcggcat tgtaactggt atcatcttag
     4921 gacgattgat agctgataat gtcgtattta tcaatgtctc aacttggcga aagcactgga
     4981 agtttagcta caaagaccgc tcaaaaaaag caatgaaagc acagtcaaag gctaaggctg
     5041 ctgaaaactt tggcaaaata gtcaaagatg atgaggcaga tgccgtcttg attggtgcat
     5101 actatgtcaa tcaaggctat cttgatggat tggagacaca tgactactac taaaaaacac
     5161 gttgtgagga tttacaacaa aggtattaca gcaacccacg cagttactga taaaaattta
     5221 tttacagagt atacatttgc gacgcagcaa gatgccgaga attatatcag agacttagag
     5281 ctaaacggat ctaagtgtgc cctttgagta ttatgagagg agatttgcaa aatgatagac
     5341 accgatacac ttgcagcagt acgggaggct gatcatgact aaaaacgact ttttaacagg
     5401 ttttgtactt atacttttag ctgcttgcat ttttgcagca ggatttgtga ttggatctga
     5461 ctgtagtagc gagcactacg agcaacaaat gacaggcttg cgtatgcagc ttgttaacac
     5521 gcagcagcag cttaagcgtg cgagtgagga tagagcaagg cggactaaaa ggattgcgga
     5581 tctgaccggg aatggaggat agggtatgat cgacgaaatc gaactcgacc tacaaaaacc
     5641 agaaatccca cagtttgtcg ctgactacat agatgatatg cacaaaaacg cacgtacatt
     5701 gagatacgct tttaaataca tggaaagtaa cataaaaatg cacaaatggt gtgtttttga
     5761 aaggcaagaa acgtttgtta atgctttttt atacggctac acaataaaaa aagaaaagct
     5821 gtatattgtt gagatcccta atcctaatag tggcatagaa cacaaacata ttgcactagc
     5881 aaggttagcg aatggaaaac ttggattttc agagatcata gatactgatt tttattcaag
     5941 agaagatgtc cgactcaccg agtcagaaat ccgcaaagat tttgattggg catggagaga
     6001 ggggtttgct aaagaggtga cggaatgagc agagataaaa ccagaatcag gaacattgtg
     6061 aagtccatga aacagttagg tgctagcgaa gaagagacag acgaatacat gtatctatgc
     6121 gtgtttaaaa agcctcacgt catagctcaa atccgtaaaa aggctaagat tttcagaggc
     6181 gaagggtggt aacagatggc atatttacga gaagaaagag aaacagttat tcattacgac
     6241 gaattggatg actgctggac ttttgaaact aacgtccgta ggcatattac gaaaatagaa
     6301 aaacgcatcg aactgtacga gattctctca gaggaattcg atgaccgagg aaggcgtatc
     6361 tatatctgtg cgaaaatgaa gacaggaact gtcagtccct ttgcgaaacc accaagaagg
     6421 aaatagctat agaatcgatt ttaagcttca aaaacatggc aagaacgcac ttctgggaac
     6481 gtgaaacacc tagctaatat aaatgtaccc tagaacaatt taaatcgaaa aaatgattag
     6541 ctacataggt tttaatcggc ttatgtggca tagaccgaaa ttaaacacag aaggatgtga
     6601 tgacaatctc cttacaccca aaaaatctaa cactggttat cggtcaccag ctattatcca
     6661 aggcgctaat actgacatcg tgtgcctgag ctggcttata aaaaacgaaa gagagggctt
     6721 ttctccacac aaaaagacgt ccatgcgaac gcctccttgg ttatatctgt taacaccatt
     6781 ataccacact gagggggctt tcatgacgtt ttttcctgag attgatatcc aaaaaacaaa
     6841 atccaatgcc aagcgtaaat tgaaagagta tccacgctgg cggcggatag ctaacgatgt
     6901 agatactcaa aaagttacag ctacttactc atttgagcca aggcaacctc atggagtcca
     6961 tagcaagcct gtagagaggt tagcacttaa tcgtgtgtca gcggagcagg agttagatgc
     7021 gattgagcaa gctgtcagca tgatactaga gccagagagg cgcaggattt tgtacgataa
     7081 atacttatca ccttataaaa aagcggacaa ggttatttat acagaattgt gtatgtcaga
     7141 gagcttttat tatgatacgc tcgatatcgc tttattagct tttgcagagc tatatagaga
     7201 ggggtctctg attgtcgagc aaggagtttt tagctagttt ttatacagta atataatagt
     7261 ttttgtacaa aatagcgtgt taatatagta tcatagcaaa ataacaaaaa gagataacca
     7321 ttttaccaat tgactattta tttagtcgcc aactttaact acgatcaaac ttgttatttt
     7381 gaaggtacat gggacgtgca ggttcgaatc ctgccgtctc aataccagct atttccaaaa
     7441 tggaaacagt tggaaaagac aaacccccca ttcctttaaa ggcagatacg ttctgatatg
     7501 gggcttttta tgattaactg caagtaaaac aagggtcgca accttgcttg tggttagtag
     7561 acctagtggt cgtttatgca cgttcgattc gtgcaaggtc tgttgggttg attgcaataa
     7621 tccttttgtg gacgcacaac aaaaatgtga tgtaagtcac ggctaaggtt tgggcggcga
     7681 tagaatagat gcgcaactat cgttgggtca cgtctcagag tttgcatagt taatattaac
     7741 cgatgggcac accctgcgtc agtgggttgt ttatggatag cttagcaaag gggttaatgc
     7801 gaccaactgt ttagtttggt aggcgtgagt tcgaatctca cactattctt tcaggaacat
     7861 gaaccgtgat tggaaaacgg tagaggtagc gccttgataa ttggattgtc gacggtctga
     7921 ttatatgtgt cggttcaatt ccgactgttc ctgttctagt caccaattgt ggtggctttt
     7981 tattatgtca cgaggaggtg atggaaaatt gctaagttaa ctataaaaca acaaaaattt
     8041 attgatgagt acatcatctg tggaaatgcg acagaagccg ctcttaaggc gggttatagc
     8101 aaaaaaacgg ctgggcaaat cggtgagcag aacttgaaaa aacttgaaat aaaatctgcc
     8161 atcaacgaac ggctaaaaca actcgaaagc agtaaaatag ctagtgcaat cgagatccta
     8221 caagttctta ctgccgttct tcggcaggat ttgacggagg aggttgttac ccttaatcct
     8281 gtaacaggtg agtacgttac tatgcagaaa aaacctagca tcgcagaagt cataaaagct
     8341 gctggtgagt tattgaaacg ttatcctatc caagaacaaa ttgaaaaaat caagcaagaa
     8401 aacgagttgt tacgccttaa aattgaaacc gtcaaaggcg ccaagcctga tacccatttg
     8461 atggaaaaac tgctggaggt aatcgaagat ggcggttagg ataaaaaagt tatccacaaa
     8521 acaaaaagac atcattagac gcccttttaa ctacgaatta gaggtcaatg agggaacacc
     8581 cagaagtgga aagaccaccg ctgggcattt tcgttatgct aggtatctga ttgagtcaga
     8641 agatgaaaat catcttgtga ctgcttataa tcaagaacaa gcttatcgtt tgtttattga
     8701 tggagacggt acagggctga tgcacatctt tgacgggaac tgcgaaatca aacatgatga
     8761 gcgaggagat cacctgcttg taacaacacc aaaaggtaat aaaagggttt attacaaggg
     8821 tggaggtaaa gttaactcag tcggtgctat tacaggtatg tctctaggct cagtggtctt
     8881 ttgtgagatt aatctactgc atatggattt tatccaggag tgttttaggc gtacctgggc
     8941 ggctaaactg cgttatcact tagcagacct taaccctcct gcgccacagc accctgttat
     9001 taaagacgtt tttgacgtcc aaaataccag atggacgcat tggaccatgg acgataatcc
     9061 aatattaact gcggagcgca agcaaaacat tatcaatagc ctcaaaaaaa atccttatct
     9121 ttataaacga gatgtactcg ggcagcgggt gatgcctcaa ggtgttattt atggtctttt
     9181 tgacatggaa aaaaatgttc tagacacttt gattggcgag ccagtggaga tgtatttctg
     9241 tgcagatggt gggcaatctg atgccacatc tatgtcttgc aacatcgtaa caagagttag
     9301 agataatggc aagataagtt ttaggcttaa tcggacagcg cactactatc atagtggagc
     9361 agatactggt caggtcaaag ccatgtcaac atacgccaga gaacttaagg ctttcattga
     9421 ctggtgtgtt aaaaaatacc aacttcggta ctctgatgtc tttattgacc ctgcgtgtaa
     9481 ggctttgcgc gaggaattac atgccattgg tattctgacg actggagcgc cgaacaacgc
     9541 tcacgacgta aacagtaagg cgaaaggtat cgaagttggg atagaacgtg gccagacttt
     9601 gatttcagac ggtgattttt atctagtaaa tcacaaagag gaaaaatatg atcattatca
     9661 tttcctgaag gaattagggc tttatagccg cgatgataaa ggcaaaccaa tagacgcaaa
     9721 caaccactca atggacgaat ttaggtactc ggtcaatgtt tttgtgggac gatacaaaat
     9781 gaaataggag gtagtcatgt ttagaaacct ctggactaaa ataaaagggg tgatgcaaaa
     9841 aatgggattg ataaaaggtt tgaaagattt gaacctgcac cgcgaaattg aactgtctga
     9901 taagcattat gatagtatcc aaatttggaa agagttgtat caaggctatc acgataaaat
     9961 acacgattac tatgagaaat ctatcttaga tggtcgtaaa aagaagaagc gtttgacttt
    10021 gaatatgcct aaagttgtga cctcagagct tgctacattg atttttaatg aaaaatgtga
    10081 aattaacatt ggttctgaaa atgagagttt gacaaagctc atcactgaaa cgttagagaa
    10141 aaataatttt actcaggagt ttcaacgctt cttagaatat agtttcgcct tgggaggtat
    10201 ggcaatcaaa gcatatctca aaaaggacgg tactatcggt cttaattttg tacaagcgga
    10261 tagttttatt cccatttcgt gggataatgc tgggattagc gaagccgtat ttgttgatac
    10321 gcagcatcgt ggaaaataca agtacacgca tttggagtgg catacttggg aaagtgagtt
    10381 gtatgtagtt gctcacgagt tatttagaac tgacaagtca aatgatgatg ttggcattcg
    10441 cgtaccgata acagagattt atccagattt aaaatcacaa gtagtcatcg aaaaactatc
    10501 aagaccgcta tttgtttacc tcaaacctaa ttcggcaaac aacattgatc tatcaagtcc
    10561 gctagggatt tcaatctatc acaattcgtt tgataccttg cgagcgattg atattgccta
    10621 cgatagcttt gagcgtgagt ttcgacttgg ccgtaagagg atattggttc cagcgactgc
    10681 cattcgtact gtagtggata gcgaggggaa tttccaccgc tattttgacg caacagacga
    10741 aacatatgag gctttccaca caggtgaaga cagcaaaatt caagatatca aagatattag
    10801 tgttgaattg cgagttgatg aacatattgc agctattaac gcactgttga acttacttag
    10861 tatgcagatt ggctttagcc caggttcttt cagtttcgat ggagtatcgg gtgtcaagac
    10921 agccaccgag gttatctctg agaattctaa gacattccgc acgaagcaat ctcatgaaac
    10981 gatggtagaa gcaacattga aaaatcttgt tgcgattatc gttgattttg gggatcttta
    11041 tggtttgatc gagggtgaga gtaagtataa tgtaactgta acgtttgacg actctattgc
    11101 gcaggacaga acccaggacg ctcagtatta tatagggttg gtcgcagctg ggttaatcag
    11161 caagaaaaaa gctatgatga agctgtttaa tctgtcagaa gaagatgcag agttggaaat
    11221 ccaaactatc cacgaggaaa gccggacaac aaacgatatg tcaattgatt tatttggttt
    11281 ggacggtgat gcttagtgga ttatgatact catatccagc tgtcttttga cttaatagag
    11341 ctttattctg atgtcgaacg tgaattgttg acgtcaatag gtcgcaggtt tgcaaaacac
    11401 tatgacgaaa tggtagctgg cgacatcatg gattggcaaa ttaggcaatt actcgaagtt
    11461 ggagagctga gaaaagagca catcgaaatc atgcgaaaaa gtgcacgcgt gagtcgtgag
    11521 cgtatgattg agatgctgac ggaggcaggt tatacctccg caggaaggta tgaggatttt
    11581 tttaaagagg catacgttaa aggtttaatc aagctcaatc catctgctgc agacaacagc
    11641 atgaggttgt tgcgagtgtt aaatacttac atcaatcaag ctgaggacac acttaatctt
    11701 gtcaatacga ccatgttaca gtctggccaa gatacttttt tagatacagt caatcaagtt
    11761 gttgcttatg tttctacagg tatcaagacc ccacaagttg ctatgcgtga cgctctaaaa
    11821 aatgctggtc aaaagggcct tacagtcttt cgtgctaaaa atggcgccca gtggtcaacg
    11881 gagacttatc tcaatatgat cactcggacg atgaactcta acatttctaa cgctatggaa
    11941 gatgagcgta ggcatgagta tggtgttgat tacatcgagg tatctagcca tgctggcgca
    12001 cgtccaaggt gtgctcctta tcaaggtcgg atatattacg atggtgtcgg agatgatccg
    12061 ctagagaaat acccgcactt ctcagagact tcttatggcg aagctgctgg attgtttggc
    12121 gttaattgcg gtcatcataa atatccttac gtcccaggta tgagtaaaca gacctttttc
    12181 ccttacagta aaagcgaaaa cgataaaacc tatgcagagt cgcaggtaca acgtaaatta
    12241 gaacgggaag ttaagcagct gaaacgggaa cgagcaattc taactgctgc gaaggacaaa
    12301 gagggggcta aattagcttc tcaacgcttg gagaacaagt ggcaggaatt gcgtcagttt
    12361 actgctcaaa caggcagaac gagacgatac gaccgcgaga aatcgctaaa tactattttg
    12421 tctgaggaca agaaaaaagc cattgtcaaa gataatttga aaatcagaga tgagtatcga
    12481 gcgattaaga aagctatccc tgaagtagct cctaaaaatc ttgaaaccta ttatgatatg
    12541 cgttataatg gtggcaagat atacgaggat ttagttaggg attacaaaga ctatataaga
    12601 tggtctaaag ctgaatttcc tactaaaaaa tcttttgaag ggcatattga tagtcactta
    12661 aaagagtttc caggattgac tggtaaacaa tatcagaaaa aggctgctga cttattatct
    12721 agaccgataa ctgataatat tttaggttat gatacagatt ctagacgtgt taggtatgac
    12781 ttagaaaata acatttttgc tttagggcgc gttaaacaag gtacgattac gactatgctg
    12841 aaaccaaagg aaggggttga ttactttgac aatgactgga aaagagagtt tgataatctt
    12901 aaatgattta gaatatgtcc attgtcctgt ttgtggaact ttgaccgagg tttatgatat
    12961 ttgcgatact tgtaaatggc agaataccgg tgagacaaat attgatggcg gtcctaatta
    13021 tattacactt gaggaagcac gacgaaggtg ggcaaatggt gaacctttgc gcaacttttt
    13081 taaagaccaa taatacaagc actgtaacag tgcttttttt gtactcaaaa aaggagagag
    13141 taaaatgaac aaacgaattg aaaagaagcg tcgcacacaa atgatgttag acagaatctt
    13201 gcgcattgta gaattgatgt cgcaagcaac tgacgacaac tttgctatct tggaaaagcg
    13261 cttagaaaaa gctgaaaaac gtaacgaaga gcttatggaa atcatcttag taaacgttaa
    13321 agaggtaaat aaccgctttg acgagctaga aatctgccag aagattgttg aagatgatgt
    13381 cgcagagctc aaaaaagcta agaaaaaagg ctggttcagc cggaaataac ttaatcgtgt
    13441 cgaattcgat gcggttttat tttgccctgc cgcatggcga taaactaggt aaaaataaaa
    13501 gaaagaggtc taaaatggct gttattatcg tacaaacacg aggcggagat attgaagttc
    13561 ccaccccatt accagcaatg caagctaata aagcgattca aagtcaatta ttcgataagg
    13621 agctgacttt tttatgcgtg gataatcatg cttttgctaa aactgaggtt ttacacgttt
    13681 tggtcgaaac agaagaagat gaagaattac cacagtcaaa acataaggag gaagaaacat
    13741 gctacatgga ttaaaacacc gtttgtttaa actagcccca gatactggag caggcggagg
    13801 cgctgaagtt actagcgaga ctaacgctga agctggacga gttgagcaaa cagtatcgca
    13861 acaacaagct gatccggttg atactgaggc aatcaaaaat caagcaatta atgaggttct
    13921 aagtcaacta ggtgtttctt cggtagaaga tgccaaagca aatctagctt cttggaatga
    13981 atatcaagaa ggtcagaaaa cagagtttca aaaaattcaa gatagtttga ctgtggctaa
    14041 taactctttg gctgagcgcg acactatgat tgctagctta caagctcagt tagctgctgc
    14101 tcaaatggga gtgcctgcgg aaaacacctc cgatgttatc actttggcca atagtttggt
    14161 ccacgataaa acagacatca atgcagcgat tactaccgta cttgagaaat atcctcattt
    14221 caaaggaggt gatgccgatg tagctgataa acctaacttt gtgactcaaa ctcagagtca
    14281 aacggaaacg acggaagacg ctttttttaa agcgttagga ctaacaatta aggaggacta
    14341 atatgtcaat caattatatt actaaacatg aaggaatatt cgaaaagaaa ctaatgcaag
    14401 gcgctttgac gtctaactta gagacaccaa aagtcaactg gttaggtgca aagtcttttg
    14461 agctaccaac catctcggtg actggctata aggcgcacac acgctcaaaa gggtataacg
    14521 caggtactgt atctaacgat aaaaatactt atacgctcgg ctttgatcgt gacgtagagt
    14581 tttttgtgga taaggcagac gtcgatgaga ctaaccaaga gctgtctatg gctaacatct
    14641 caaacacttt tatcacagag catgcaacgc cagaagttga cgcttatcgc ttttcgaaga
    14701 ttgccacaaa tgcgatcgat aatagccatt ttaagcagga agatgactac tctactacta
    14761 atgtttatga gcgcttaaaa gctgctattt tgcctattcg caagtacgga gctggcaata
    14821 tcattatcta tgtctccagt gagattatgg actttttgga gcgctcaaag gactttacac
    14881 gctcaatcgc gacaacatca ccgcaaggga ttgatactcg tgtgacatct cttgacggag
    14941 tgcagctcat agaggtttgg gacgatgccc gctttaagac taaatttgat tttacgacag
    15001 gctttgtcaa agatggcagc ggtaaagaca ttaacttttt gattgtggcc aagcctgcgg
    15061 ttattgcaaa agctaaattt aactctattt atctttttgc accaggtcag cacaccgaag
    15121 gggacgggta tctatatcaa aatcgcttgt atcacgacct ttttgtgctt aaatctaaac
    15181 aagatggggt ttatgtatcc cataaatcag cttaggaggt taacgatgaa aacatacgag
    15241 aaggacaatc aagtctataa agtacaagaa ggcagcgagc tggaaattca gctgattgcc
    15301 gacggcttta aagaaattat tgaagcaaac gaaaaggaaa ctgatatcac taaaatgaag
    15361 cttgataagc taaaggctta tgctgaaaat gaaggcatta taattcctga agatattaag
    15421 aaaaaagaag atgttttagc ttttattaag gaacagcagc agagaggtga gtagtgatgc
    15481 tcacctttga tttttacaat aagggatatt gtggctcaca gctgaatgaa gaaaagttcg
    15541 gggagctgtc aaaacgtgct gagcgtaaaa ttttggcact tattggcttg aaaaaggagc
    15601 aagtgaagaa tttgccactt gatattttag aggcggtaaa aatggctgtc tgcgcccaaa
    15661 ttgagtatct taacgcaata ggcgttgaaa gtgctatcgg agtaacctct gtaacccaag
    15721 ctaaagtcgg caattttagt tacacagacg gaaagaaagc gactgtatca gctagtgttg
    15781 gctctgttgg tgttagccct gacgtgctag actatctgct tccgagtgga ttgttataca
    15841 agggggtgaa tacgagatgg taaaagaagt caaacctatc cctaaagagt tattagttga
    15901 cacagttact tatctagcag ttggcaacaa agacagctgg ggagcagaaa cggtagtatc
    15961 tacagaattg tcacaggtgt tagtacaacc tagaagcagt atccaacgtg ggcaacaaaa
    16021 cgagagtaat agctacgagt tgttactctt ttttgattgt gtaaactcgt taccagtaga
    16081 tcatcagttt aaggttgacg acaaaattag ttatctagga aaagagtatc gtatcgcaag
    16141 tgttgaggta ctaaaagctt ttgaccagtc gccacatcac tatgaggtga tgctagaatg
    16201 ataggtttta aggttgaagt catctttaac gctagtaaat tgattgccaa gagtgaagca
    16261 tctgcaaaga cagctcgctt tgctttaagt ggtcaaatca aaaaggatag tgacaagtat
    16321 attcctgctc gtgagtggaa tctgcgagat agcggaagag taactgaacg ctcagtatct
    16381 tggcatacac cgtacgctag acgactctac tacaatcctc agtataactt tagcaaggat
    16441 aagaatccga atgcacaagg caagtggttt gaggttgcta aagcaaatca tgcagagcat
    16501 tggtatgagc taacaaagaa agcctatggt gctgagttta gaggagatta atcatgacat
    16561 ttattgattt tttgctcaga aaagttcaag aagtgagcgg agcggaaccg gtccttggca
    16621 ttatggggaa tagtgataag gttgctatta tccctatggc tggaaatttt gacaatcgag
    16681 ctcttgacga aagtaagatt aggattttta ctttccaagt tttggccaag agtaaaaaac
    16741 agcaggaagc ttttttgaca acagaaaact tggtcaatgg tctagacggt ctatcaaatg
    16801 agccgtttac tggaggatat ctcattaagc tggagtgtac gacgaccact aactttgttg
    16861 aaaaagatag tgacaaaaat tatttatata cagctctttt cagagcagaa ttaggaggat
    16921 aagaaatggc agcagataag ccaacttttt atttacaatc cgagcataag ctcgaaattt
    16981 cagaagatgg aaaaacttgg atgcgactag caggtggtat cagtgaatta gaaccagacg
    17041 gaaatgaaga agtatcacaa gatgcttatc ttgacggctc tgaatctgat gttacaggag
    17101 gtcagctagt actagcctta actggacatc gtctagtagg agataaagct caagactgga
    17161 tctatgcacg tcaattccga tatgggggca aacgtcgtgg ttttacgcgt tggacattgc
    17221 caggaggaaa aacacagttt acctttgcct ctacgtttgc aaatatcaaa ggtccatcag
    17281 gagcggctaa cggtaaaggt gaaattgaat ttgaaatcca ttcgaacgaa acacttgtac
    17341 ctaataaagt agttgtagaa gtcactaaga caaacaaaga acttgcgtct gaagcacttg
    17401 gtttagaacg tcaagagcga taagtagaaa ggatagtcag caatggtgag acagtttgaa
    17461 tttaagaaaa cggttgaaga aattgagatt gcaggggaaa tctacttact gcctcttgat
    17521 gatgataacc tcttacgtat ccaacgtgac tttattagtt acggaaaaga gatcgaagaa
    17581 ctccaaaaag ttgaggtaga aaaaggagat ccagacgatc tggcggataa tcataagcaa
    17641 cagcttttag taatgaaaaa ggtcatcgag tcaccatttg gagaagggag ttttgagaaa
    17701 ctttacgaag catcagggca ctctttaatg aatatggttg acttattgga ttatcttgtt
    17761 gagttagtcg ctgaaaaagt tgagcaaaat aaggctcgtg ccactaaagc aaaagagaag
    17821 tattactcct cgaagcgcaa gaaaaagtag gtagcttatg aagttgacag aaacatatga
    17881 agttcttgct gatgcttttg aatttggcgg tcatatcgta actgttgact tggcttttga
    17941 tgtcgtgttg cgagtcatgg agcttcttgc cgacgcagaa gtcaatgact acgctaaaat
    18001 tgtctggact ttggatatgc tcttgccata ttttgatcgt acggagttaa gttttgatga
    18061 agaatttgaa attttcgaat atatcctaaa gacgtttatc tatgaacaag aagacggaga
    18121 agatgacagt ttaggaggaa tgtcacaaac gaaaacaatg cattttgaaa aggatgcaga
    18181 gttaatcttt gcgtcctttt ttcaaagtta tcatcttgac ctatttgaac aacagggaaa
    18241 attgcactgg cgaaaattta tgtcactgct catgaatctg cataaagaca ctccttttaa
    18301 ggaagttgtc agctatcgtg tcatgaaagt gcctaataaa gatgaagcat cggaagagta
    18361 tatcaaacac gtcaagaaga tgaagcgtat ctattcgcta gaagacgaat ctgagcatca
    18421 agcgctaaat gatgacaagc tttcagcgtt agcagcaagg tttggaggtg agtagatggc
    18481 agatggtagt gttattattg ataccctgct aaagactgag aaatttaacc aaggtgtagg
    18541 gaaactacaa ggtaaattag ctggattagg atcaaagttg accagcattg gtaccggtct
    18601 aactctaggc ttaactgctc ctattgtagg aatcggagcg gcatcgctca gcacgtttac
    18661 tacatttgaa agtcaaatga atcgtgttaa ggcgatttct ggagcaacag caagtgagtt
    18721 cagaaaacta gaagaccagg ctatcaaact tggagcttcc tctgttttta gtgcgacaga
    18781 agtagcacaa gctcaagaaa tgatggcttc tgcaggtttt aaagtcgtcg atatcttaaa
    18841 agcaatgccg ggtgttatgt ctctagctgc tgtatctggt ggggatatgg cattagcaag
    18901 cgaggcagcc gcaacagctg tcaatatgtt tggacttgaa gctaaagacg cagcccatgt
    18961 tgcagatgtt tttgcacaag ctgctgcgga tactaacgca gaagttggag atatggcaga
    19021 agccctaaaa tacgccggac ctgttgctgg ggctttaggg attagcttgg aagaaaccgc
    19081 ggcagcaatt ggtatcatgt ctaatgcagg cattaaaggg tcacaagcag gaacaacttt
    19141 gaggacaagc ctttcacgac ttacggatcc aactaaaaag atgcgaggaa tcatgtccga
    19201 attaggactt gaatttttcg atgttaatgg aaaaatgaag tccttatctg gtattaccaa
    19261 agaacttcaa accaaaatgg gtgatttaac tgatagtcaa aagagtgcag ctatctctac
    19321 tttgtttggt aaagaagcaa tgtctggaat gcttgcccta gttaattctg ctcctggcgc
    19381 attagacaag caaacacaag cacttatcaa ttcaaatggt gctgctaaag aaatggcaga
    19441 caccatgaat agtggtgtca agggatcgat tgaggagctt aaaggttcgc ttgagactgc
    19501 tggaatctcc ataggtaaaa tattggcgcc agccctaacg tcggttatcg gggcgataac
    19561 aagccttgtg aattggttca ataacctaag tccgacaatg caaaacgtgg tagttgtact
    19621 cggaagttta cttgctgcca ttggaccggt tgtccttatt ataggggttg ttactactca
    19681 gatagcagct ttccagcaag gcgtcggact agtctttaat gctgtcaaag gattacaagc
    19741 tgcttttgcc tttttgacga gtcctatagg gttagtcatc gtagccatag gtgcactaat
    19801 tgccgtattt gtttatttgt ggaatacaaa cgaacaattt agaacgaaga tcattgagat
    19861 ttggacggct atttcgaact ttttacagcc catcatacaa tttattggta atttcataag
    19921 ggaaacgtgg actcaattag ctactttttg gaacgaaaat caagcaacta ttatgacaat
    19981 agcccagaca acttggtcat ttatccagac gatatttaca acagcaattg aaatgataaa
    20041 attggccgtt agtgtttttt tagggttatt gcaatcaacg tggtctgtaa cttttaattc
    20101 tcttaaggtt atcgcacagg tcgcatgggc ttttatttcc aatgttttca agggaagttt
    20161 agggtccata cttgcggttg catctgctat atttgagcaa attaaatcaa cgattgatct
    20221 tgcgatgaaa attattcaaa atatcatcaa aatcatacta tccgcgatag aaggtgattg
    20281 ggacggtgta ttagaaggta tcaaaggaat tgtttccgca tttggagatt ttattcaatc
    20341 aactttctca aatatgatgg atactgctaa acgcttagtc ggagctggaa tagataccgt
    20401 aaaaggaatt ttcgattctt tgtggaatat tgacttgttc ggagccggtc aagcgattat
    20461 taatggattc ttaaatggtt tgcggtctat gtggggagct gtcacagatt tcgttggcgg
    20521 tattgcaagc tggattgcag caaacaaagg tcccatctca tatgataggg tactattgaa
    20581 gccgcatgga aaagctatta tggacggact cggtaatagc atgaaaacta actttaagga
    20641 cattcagaaa gatgtttctg gcatggctga cgatttaaca agaagttttc aaatcaaaag
    20701 gttcaacggt tttttgccag aaaagtatac tactaagctt gatgagctta aaaaatatgc
    20761 gcaagccacg cttggcggaa tgattttagc ccctaacatg gcagttcaac cgacagtcgt
    20821 tgttaacatc agcaatgaag cagatagcga tatcatcagg caaaaagtca atgctaagaa
    20881 tgcacaagat gctattatta atcagttatt caagaaaggg taaaacatgt tcagtataga
    20941 gtttttagac ggagagcgac taagcgccga tgaacgagga tggaaagtta aagagatgtc
    21001 ctcatcagga cttgaacaaa acgtcgttag cgagtctcct aaaatgcgtt ctggtcgcct
    21061 tgtttatggt ctttatcatg gcatcaaaac ttatcaactt gtttttacaa aaatcattaa
    21121 agataccctt gattatagcc gtttagtaga tgaagttaat tactattttt tacgtgatga
    21181 accatactat ctttaccgcg actttagaaa gaaagctgat cgggtggact tgccgaagaa
    21241 gcgggcgaag gtgtttacta agtcaatcga ccatcaaaaa aatgggctta aagttgaatt
    21301 tacagctaag ctggaatctt atgaactacc ctacgaagaa gatactgagg ttcagcgggt
    21361 cacttggacg gcaacacatt catggcacaa taagggaggg catcgccttg accctcgtta
    21421 ttgcccaatg aagatgacca taacagtatc aggttcagga gctgaactta aggtgctatt
    21481 taacggtcag ccttattttt ggtataaaaa atcagttaaa caaggggata tctttatcat
    21541 tgatgggacg gacgttgaaa aaaatagata caattgtttt gaagattgcc ataagcaaac
    21601 ctctttttta aaaacaggaa ataacagaat agatattcaa ggagcttcgt gtgaagctct
    21661 ttttgaatat agactactgt atttgtagga gggttagtat gcaggtaaaa acaaagcaag
    21721 gtgtttttta tgttaacgca gactacaccg tcgtcgaaaa acaaggtgac tatcctaagc
    21781 taacttgtac tattcctatt aagggaaatg agacttggat agcagattgc caagaacttg
    21841 accgcttata cccagctggg gaacaagatg aatttattat tatcaatcct attaaagtca
    21901 ctaaggggag ttcgtatgat ttggaaatta cagcgatagg agcctttcat tttgaatttg
    21961 taaaggctcg tctatatgaa gaactaccag aacgaatgta tactttagat tacttgctcg
    22021 atctcctgtt taaagacagc cgattcagtt ataagctaca aggtgattat tctactagaa
    22081 ggttcagtgg cttcggagat gataacaaac tgactttatt ccatcattta atggaacgat
    22141 ttcaaacaga atttaaagtt gttggcaagg tcgttttagt taacacaaaa gtaggtaaag
    22201 atacaggatt tcagttccgc tatcttagaa atatcaagga tacaaagtac tcggtagacg
    22261 taactaacct gatgacatac gttaaaggat atggagcctg gtttgatgaa aatgaccatt
    22321 caaagggaag attaattgtt gattatgaga gccccttatc caaagagtat ggcaaacttg
    22381 atggtaagcc cgttgttgat gaacgaatga gtttaaaaga aagtcttatc aaaaaatgta
    22441 agctagccgt agatcgctct gtatctgtca gcttaacaac gactttagtc tctttaaaac
    22501 aacaggatta tcaaggtgcg gcgagaatag gagactctat ttggtttatt gacgaacgta
    22561 tatctattga aaaaaagatt cggttcagcg tagtaacaac ttactacaat gcatatgatg
    22621 atattttaaa gcaggacgtt actttaggtg ataaagatac ctactctcga tatcaaagtt
    22681 tagaaaactc ttctcaaaca gagacaaatg attttcaaaa agcgatgagt agcaaacttg
    22741 cagaagttca agatgatgtt aaaaagacgc atattttagt atctggcact actaggattt
    22801 tcttttctac agagtttcct caggataatc ctaagggaac tataaaagaa gatgacattt
    22861 tgtaccgtaa tcacgatggg acaacattga tgtacaggtg gaatggtgtt caatgggaat
    22921 tagtcccgtt ggtaaacgat ccagatcgtt ggcgtgagga actggagaaa caaatctctg
    22981 aggctgtcga aaagctcaaa caagagcaaa aagtaatcaa ccagagaacc gataaagagc
    23041 tcgaagagtt tagagatacg ctcaaaaacc tatctttacc agaggaagcc attaaaaaaa
    23101 tcacagaggc tatcaaagtt gatgatatcc cgtcgattaa acagtcattt gatgacttaa
    23161 aaaataaagt cagcgagaca agcgagaccg cacgattaaa cgctgagatt atcgggacag
    23221 atggcaagac ccgctacaac aaaaatttgc tagtcggcga ccccaatcgc acaaaaactt
    23281 atgatcaaga ttatatagag ctcgaggcca acgacggtgg ttttagacgc ggcgagacat
    23341 acacgattag ctttagccag acctgtgagt tgctcaaaaa agtggctatc acgctgacgc
    23401 aagctaataa taagggagtt aaactggtac tgacacctac caaagctaag atg
//
LOCUS       DARYXS010000026        23290 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.026, whole genome shotgun sequence.
ACCESSION   DARYXS010000026 DARYXS010000000
VERSION     DARYXS010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23290
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.026"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..1334)
                     /locus_tag="TV193_000821"
     CDS             complement(<1..1334)
                     /locus_tag="TV193_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1513038.1"
                     /translation="MLTMKHKMLIFCLLLSIFVSQFHMLHVYAETSSKTQYNILIKES
                     LDTNKVKKQLNDQGMIVLDEIPEINVLTIAAANDSSMILEKNCNYIDDISRNNTFTVN
                     PKMTYQFGHAFYLDSDLNYWNKQWDMQRSISTSSRFWHKSSGEVTIGVIDSGITDNNT
                     DISSKIISVQNFTEDPVTKAIDVNNVLDKTGHGTSVVGQMSSNGYYTGIAPGMKVRMY
                     KVFEEGNAQDEWILKAIIQAAKDDVDVINLSLGQYLLKASSNIDEDRTALINSYQRAI
                     NYAHKQGSVVVASVGDEGANLNNQAELKNLVSALTGRAFSSVDGTIEDIPAQLDNVVT
                     VGSVDGDGAISNFSNRGRNVVDIFAAGGGSKKLALHGYDTWINNKLFEQDWVIIPTLE
                     GKYTYGYGTSIAAPKVAAALGLIIEKYDLKDKPDEAITILYSNSWSSLDDNG"
     gene            complement(1502..1633)
                     /locus_tag="TV193_000822"
     CDS             complement(1502..1633)
                     /locus_tag="TV193_000822"
                     /inference="COORDINATES: protein motif:HMM:NF022534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513039.1"
                     /translation="MEEETKLNQETMTTMIGKYECYARQLEKLAFVFNYKSELRTKD"
     gene            complement(2742..4688)
                     /gene="thrS"
                     /locus_tag="TV193_000823"
     CDS             complement(2742..4688)
                     /gene="thrS"
                     /locus_tag="TV193_000823"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEL1513040.1"
                     /translation="MITITFPDGAVREFESGVTTFEIADSISKSLAKKALAGKFNGQL
                     IDTTRAIEEDGSIEIITADHEDAFEVLRHSAAHLFAQAAKRLFPKLHLGVGPAIADGF
                     YYDTDNADGQISNEDLPRIEEEMKKIVKENFPCIREEITKEEALELFKDDPYKVELIN
                     EHADDAAGLTVYRQGEFVDLCRGPHVPSTGRIRVFHLLNVAGAYWRGNSDNNMMQRVY
                     GTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYYDNDEMWENAQSMLKAA
                     LDEMGADYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFNLSYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPRQVTVIPISNEAHIDYAWEVA
                     KILRDHGIRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMQDKSVNVRRYGSKATH
                     TEAISAFVDNILADIARKSRPAEG"
     gene            complement(5279..6613)
                     /locus_tag="TV193_000824"
     CDS             complement(5279..6613)
                     /locus_tag="TV193_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1513041.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDKH
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKEYHLDIIHTQTEFSLGLLGK
                     MVGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIALENYVREDIKKEDVAALRKELAISDDETMLLSLSRVSY
                     EKNIQAIIHQLPAVLSENSRIKLVIVGDGPYLQALKELAVSLGVEDHVVFTGMIAHDQ
                     VGLYYKACDFFISASTSETQGLTYIESLASGKPIIAHGNPYLDDLITDKMFGTLYYAE
                     SELSDAIIDAILETPQMNQRLLDEKRYEISAQHFGKSVYTFYLDTLISRHNKETKKLS
                     LYLNRTEKSGSIKLVQGAIHLPKRAAKATALTSVKVLKAPIKLVNAIRDFLD"
     gene            complement(6615..7613)
                     /locus_tag="TV193_000825"
     CDS             complement(6615..7613)
                     /locus_tag="TV193_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1513042.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQEFTTDPKDDY
                     DLVHLNTYGLKSWLLMSKAQKAGKKVIMHGHSTEEDFRNSFIFSNLVSPLFKAYLCRF
                     YNKADAIITPTPYSKALIEHYGVKTPIFAVSNGIDLEQYGANADKEAAFRRYFNLKEG
                     EKVVMGAGLFFLRKGIDEFVKVAEMMPDVRFIWFGDTNKWVIPARVRQIVNGKHPDNV
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYEGWIDQ
                     DSAELANDTSGFVAALRRILSGESNKTEAGYRVAEGRSLDRIAHQLVAIYQKVMEL"
     gene            complement(7909..9384)
                     /locus_tag="TV193_000826"
     CDS             complement(7909..9384)
                     /locus_tag="TV193_000826"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1513043.1"
                     /translation="MSHQLLMQAFEWYLPADGRHWQRLKSSIPELQQLGVSQLWLPPA
                     FKGTSSDDVGYGVYDLFDLGEFNQNGTVSTKYGSKEDYLQLIAALKEAKIKPIADVVL
                     NHKANGDHKERFSVIKMNPENRQQALTEPYEIEGWTGFDFPGRQNTYNDFKWHWYHFT
                     GLDYDAKANETGIYMITGDNKGWANDELIDDEHGNFDYLMYNDLDFKHPEVIQNLQDW
                     AKWFIETTGIEGFRLDAVKHIDSYFIQTFINDIRTQLKPDLEVFGEYWKSDQESMEDY
                     LEATKAQFALVDVALHMSFFNASQQGADFDLTTIFDGSLVASRPDLAITFVENHDTQR
                     GQALESTVEEWFKPLAYGLILLRQEGKPCLFYGDYYGISGDYPQQSFKEVITKMAELR
                     QQLVYGEQIDYFDHANCIGWTCLGDDQRPQPLAVVLSNGDAGWKHMEVGQAYAGQVFC
                     DFLDNCQETVVVAEDGWADFKVEAGSISAWVLQKAQPKEEA"
     gene            complement(9454..10455)
                     /gene="ccpA"
                     /locus_tag="TV193_000827"
     CDS             complement(9454..10455)
                     /gene="ccpA"
                     /locus_tag="TV193_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEL1513044.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTDKIRAEFSRSRTPIVLAGTVDLDHQLPS
                     VNIDYKAAVADVVDILAKDHQSIAFVSGPLIDDINGKVRLAGYKDGLKKNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            10629..11714
                     /locus_tag="TV193_000828"
     CDS             10629..11714
                     /locus_tag="TV193_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1513045.1"
                     /translation="MTKLDQIRLYLNQEKAELAIFSDSVTINYLTGFLCDPHERQMFL
                     FVYHDKAPVLFVPALEVARAEQLLDFPVFGYVDSENPWEKIKSVLPSTAAKTIYAEFD
                     HLNITKFQGLQSVFSGRFDNLTPYIQRMRLIKSADEIQKMLIAGEFADKAVNVGFDNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGNNAANPHGIPGTNKIENNALLLFD
                     LGVETLGYTSDMTRTVAVGKPDQFKLDIYQLCLEAQLTALDMIKPGVTAAQVDAAARQ
                     VIEKAGYGDYFNHRLGHGIGMDVHEFPSIMAGNDLILEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKDGFELFTQTPKELLYFEG"
     gene            complement(11888..13471)
                     /locus_tag="TV193_000829"
     CDS             complement(11888..13471)
                     /locus_tag="TV193_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513046.1"
                     /translation="MKSILQVISKWQLCLYSLLALLYSLQGLLLSVLIQIAGQIDMNN
                     KGMVLLFGLGGVAFFVFIYMCMYLNNILARSMVRAFNCLIAKKALYHFYHKQLNYFTS
                     ALNSFLTQDIPMFWQEYLVPLFIYPVFGLSILASVLYLLLQDIYIGIAFTIGGFLMII
                     PQFVFNHLLQSRGLELSQAREKSLASITDFTKGADTIQSNQANEAFAHHVLEMIQHME
                     DKQYSYYTTHNLVMFWTGPLKGIGLVSPLIIGLLVMSYSSLSLTTLIAMITASTNLVS
                     PLQQLLEATSSLQSATAVKEKMVRVLALEEETKHQALTPTDDLTLDIYFKRLDKYFDH
                     RLIFQGIDGHISAGHKTLLTGASGSGKSTLFALLCGEDKDYSGTIYFEAANGKRYFPS
                     YDVVSLIHQKPYIFEGSLRDNLTLFQDYSDQRLKEILQQVHLWNELNGDLDLHLDGQN
                     LSGGQIMKLEIARCLLILKPILLADEVTAALDKESAREIRELLHSLPCTMVEIAHKYN
                     AQSYDCIYHLKDKELVRCS"
     gene            13709..14560
                     /locus_tag="TV193_000830"
     CDS             13709..14560
                     /locus_tag="TV193_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1513047.1"
                     /translation="MNIREKFKAIRKQRRLSLKTLGKIAGSATSISDFENGKTNLSND
                     VLLQLLGFMIVEINELFEWEDFHEKELVEAIKQIELAIKSKHIPALSQLQQDFQSLSK
                     TKEQYIYHIISLILTITIAEYQNKEIDPHIMSELTDYFFFLEYWTNLDVGLLGNIVHY
                     MTTDALILLTNDILEHTPQVLRNNLDRIRIDTVLNCLTVLINRKEEKASRTLLKLLFN
                     KHYPNYFAFEKLYLHELQAVYDFNWKDKEQALAAHHVILATISLLFTADEAKEWDSFF
                     QESTSSL"
     gene            14821..15489
                     /locus_tag="TV193_000831"
     CDS             14821..15489
                     /locus_tag="TV193_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1513048.1"
                     /translation="MSHKSIHQQLRNAFSFRTAVRVYNDQKIAKEDLDLILDAAWLSP
                     SSIGLEAWRFVVLENEAVKHELKEVSWGAVYQFETASHMILLISEKNARYDGASIKQS
                     LLRRGITDEQALASRLACYEAFQKHDMKIADDPRALFDWTAKQTYIALANMMTTAAFM
                     GIDSCPIEGFNYDKVNAILAKHGIINPDTEGISSMLSLGYRLRDPKHSQTRKPREEVI
                     SFFN"
     gene            15604..16530
                     /locus_tag="TV193_000832"
     CDS             15604..16530
                     /locus_tag="TV193_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1513049.1"
                     /translation="MTLLSVIIPCFNEEDTIIPYLEEMKQIEAAMTSQLAFEYLFIDD
                     GSTDQTLSVLRELAGRFSNVHYLSFSRHFGKEAGLLAGLEEAKGSYITVMDVDLQDPP
                     ELLPLMYSKLQEGFDVVATRRQSRQGEPAIRSFFARLFYRLVKHVSNTEIVDGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYNTAYISFDNRKRQYGKTSWNFLELLNYSI
                     DGFINFSEMPLTIATWTGTLSFLLSLLAICFIVIRKLLFGDPVSGWASTVSIMLFIGG
                     IQLFCMGIIGKYISKIFLETKKRPVYIIKEKK"
     gene            complement(16514..16702)
                     /locus_tag="TV193_000833"
     CDS             complement(16514..16702)
                     /locus_tag="TV193_000833"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513050.1"
                     /translation="MTLSRLFRCEADARSHTKKDLMVLIGTIKSFCRACHDEGNQSLS
                     ASLAADRGLDDCSVISFL"
     gene            complement(16814..17281)
                     /gene="smpB"
                     /locus_tag="TV193_000834"
     CDS             complement(16814..17281)
                     /gene="smpB"
                     /locus_tag="TV193_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEL1513051.1"
                     /translation="MAKGEGNVLAQHKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTG
                     MTLIPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR"
     gene            complement(17284..19608)
                     /gene="rnr"
                     /locus_tag="TV193_000835"
     CDS             complement(17284..19608)
                     /gene="rnr"
                     /locus_tag="TV193_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEL1513052.1"
                     /translation="MMIENITNYLKEHGQSNIHDLAAALEMTDAGSFPRLIKAISKME
                     GKGLLSFSDEGEVFLRAPQQKKPEIRVQGIFRANKAGFGFLSVDDNEDDIFIGRDDVG
                     YASDGDRVEAVIKKPANRLKATAAEARVVAIVERSLKTVVGRVILDDDHPKYAGYIKS
                     KNQRIQQRIYIAKSPIALDGTEIIKADIVQYPKAGQDYFVGTVCDIIGHQHDVGIDVL
                     EVLESMDIVSAFPDDVLAEANAIPDAPSDQDLMGRVDLRKETTITIDGADAKDLDDAI
                     HIKRLANGNVELGVHIADVSYYVTEGSALDREAAARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPKVDRLTQSAIMEIDHQGHVVDYQLCQSVINTTFRMTYSAVNQMIAGDSEALRE
                     FDRIADDVSTMVELHQILEAMRVKRGALNFDTQEARIIVNDKGMPVDVVLRQRGVAER
                     MIESFMLAANECVAEHFSRAGLPFIYRVHEEPKAEKLQTFIDYASAFGIQIQGTANKI
                     SQEALQAFMAKVEGSPGAEVLNMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRR
                     YPDLLVHRMIREYNQITQEKVDHFAQVIPELAVSSSQLERRAIDAERVVEAMKKAEYM
                     ADYIGDVFDGVIASVVKFGMFVELPNTIEGLVHITNLPEYYHYNERTLSLKGERSGKV
                     FRAGQPIRVRLVRADKETGDIDFDYLASDYDVVEKTTRSAKAKHKHRQKAASRASRSK
                     ESKPSKPKSKQKTRKKAKKPFYQKAAKKKGRKRS"
     gene            complement(19695..19931)
                     /gene="secG"
                     /locus_tag="TV193_000836"
     CDS             complement(19695..19931)
                     /gene="secG"
                     /locus_tag="TV193_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEL1513053.1"
                     /translation="MYDLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLGIALVLAILSSK"
     gene            complement(19977..20123)
                     /gene="rpmG"
                     /locus_tag="TV193_000837"
     CDS             complement(19977..20123)
                     /gene="rpmG"
                     /locus_tag="TV193_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1513054.1"
                     /translation="MRVKIHLECSHCGSKNYLTSKNKTSHPEKIKVPKYCPKERKVTL
                     HVES"
     gene            20611..22497
                     /locus_tag="TV193_000838"
     CDS             20611..22497
                     /locus_tag="TV193_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1513055.1"
                     /translation="MRKTMKKMLAASTLCIIMSGSFISGSARVLAEKYYGFNDGTGEH
                     SPFPVYVTPITKPNRNTAKVVYCFNKDMKWPETWDKAAPKKPDNLPLYYDMEGTDQLF
                     STYASGQLTPNVSKVLANIMAKGYPNNNEFAHHFKLTPNSAVKVTQIAVWTVTDNLKN
                     YSQYSLTREEEAALNYLTDKNGDDFSDSIKLKLYIPQNPRTIKYQNLLGYDLIVKTPE
                     KKDNCKCTKIYIEDNGKDGYYLYIYYDNNENNRYDSDKDSLLQKKYIKNGKDGKPGRP
                     GVPGLPGPAGPQGPRGDKGETGERGPKGEKGLDGKPGEKGPKGDTGKDGKDGQPGPQG
                     PKGDPGRDGKDGEPGKPGERGEKGPQGERGPQGLPGPKGEPGIPGPKDEDGKDGAPGH
                     DGQPGPKGEKGDPGQQGIPGPKGEPGRDGKDGEKGERGEQGPQGERGEQGPQGERGEQ
                     GPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQG
                     ERGEQGPQGERGEQGPRGENPTPTPDPMPQPEPQPEPQPMPDPAPKPESKPEPKPIPQ
                     PEVKPQPETKPQQPNKPSTITSQSSGKSLPKTNDTGSLITAFGTGLLTLLGLGFLAKR
                     KRKQ"
     gene            22811..>23290
                     /locus_tag="TV193_000839"
     CDS             22811..>23290
                     /locus_tag="TV193_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1513056.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGSARILAEQYYGWNDGTRVK
                     SPFFLYVTPTNETTRKTGKNGTIVYCFNRDKEWPANWEEGRSLELVNAETAYKLPIYN
                     KLLGTTDSFTKNASKPRVSGDIGKALIAVLKNGYPNKNLSGLDDTKSRILTQLAIWYF
                     "
BASE COUNT         7093 a         5378 c         4345 g         6474 t
ORIGIN      
        1 tttccattat catccaagct actccaagag ttactataca aaatagttat ggcctcatct
       61 ggtttatctt ttaaatcata tttttcgatg attaaaccta aggcagcagc tactttaggg
      121 gctgcaatag aggtcccgta gccataagta tatttccctt ctagtgttgg gataataacc
      181 caatcttgct caaataattt attgttaatc caagtgtcat agccatgaag cgctagcttc
      241 ttgcttcctc cacctgccgc aaagatatca acgacattcc ttccacgatt ggaaaagtta
      301 gatattgcac catcaccatc aacagatcct actgtcacaa cattatctag ctgtgcggga
      361 atatcctcta ttgtcccatc gactgaacta aacgctcttc ctgtgagagc actgactaag
      421 ttcttaagct cagcttgatt atttaagtta gctccctcat caccaacaga agcaactacc
      481 actgagcctt gtttgtgtgc ataattgatt gcccgttgat agctattgat tagagcagtt
      541 ctatcttcat caatatttga tgaagccttt aataaatact gaccaagact caaatttatg
      601 acatcaacat catcctttgc tgcttgaata attgctttta aaatccattc atcttgagcg
      661 tttccctctt caaacacctt atacattcta accttcatgc ctggagcaat tcctgtataa
      721 taaccatttg aagacatttg tccaacaaca gatgtaccat gacctgtttt atccaaaaca
      781 ttattaacat caattgcctt agttactgga tcctccgtaa aattttgaac agaaatgatc
      841 tttgaagaaa tgtcagtatt attatcagta ataccagaat ctattacacc aatggttacc
      901 tcacctgatg acttatgcca aaacctacta ctagtactaa tacttctttg catatcccat
      961 tgtttattcc agtaatttaa atcactatct aaataaaatg catgcccaaa ctgatatgtc
     1021 attttgggat ttactgtaaa agtattattc cttgaaatgt catcaatata gttacaattc
     1081 ttttccaaaa tcatagatga gtcatttgca gcagcgattg tcaaaacatt aatttcagga
     1141 atttcatcaa gcactatcat tccctgatca tttaattgct tttttacctt attggtatct
     1201 aagctttctt ttataagaat attatattga gttttgctac tagtctcagc atagacatgt
     1261 aacatatgaa attgagatac aaaaatagac agtagcaaac agaaaatcaa cattttatgc
     1321 ttcatggtca gcactccttt aagtattgtt tttacactta tcgtatgact aacatttcag
     1381 atttgtttca gattctagaa aataatactt actattgtgc ttatttaagt ccaaaaatta
     1441 gcattacact cattaagtat ctgagattaa tctagctaac attctaaatt gttttctccc
     1501 actaatcttt tgttcttaat tccgacttat aattaaagac aaaagctaat ttttctaact
     1561 gcctcgcata gcactcatac ttgccaatca ttgttgtcat cgtctcctga ttgagcttag
     1621 tttcttcttc cacctgctcc agtttactag ctgatatgca agtgcaatgg tcgttttttg
     1681 tgaatcacac ctactttgaa tctggtaaaa tcattctact aacaaacttc ctgtgtaatt
     1741 tctagtagcc taggtagcct gataaagaga tttcttcaaa taaaaataac catgtcgaat
     1801 gccagcgctc catttcttac cagcattttc attattcccc agctaaagct ctatccatga
     1861 ggctaagtga cctgtgctta gaattaactc atatccacac tagtctcaga aataaagact
     1921 gaagctatca tgatgtcact actaggaatg aatgaaatct agggtttcta cttgacagtc
     1981 atagtgagac aaacaagcgg caatttgctc ttctaaactc ccgatttgtt tctaatagca
     2041 agcataaatc tccatagact acccccatag aaaatggtgg tgattggaga aatcaccatt
     2101 aagtgcttca cgacgttgag gagctttctt cttcaaacta gtataaacaa ttaatggact
     2161 acttactcta gctgtcatag gcgtttgagc aatcagtagt tgaaatagct tgcaaccgaa
     2221 agcacccagc atactctcaa tgcggatcgg aagttcaatg ccacctaact gtagaatttt
     2281 ataatgcaaa ttgtccttta ttaagaacct tattgatcat tttaagcttt agttcgggag
     2341 aggaacgaat ctttttcctt agcagcttta caatcaatta atcgtgctaa atactttaaa
     2401 tggaattgat tgatatcaaa ttgtttgaat gaataactct ggttttgtag gccgcagatt
     2461 tctaccttgt cttgatgtct taatgtcatg ttaaaagcac cccattcgtt agatagtttg
     2521 tctaactttt ggggcgcagt tcattcatta gattttttat ctaatttttg agaagcagtt
     2581 tacttctgat gagggcttct atattgcttt cattagttct atgagtgaga gcaaagctct
     2641 tgtagctatt tgtcccagat ttttttatgt catctgtttt gcaagtcaag ctgacgtctg
     2701 cttaatcagc ctatctaaaa ccagcttgct tggtctgctt tttagccttc agctgggcgt
     2761 gatttgcggg caatatcagc caaaatgtta tcaacaaatg ctgaaatagc ttcggtatgt
     2821 gttgccttac tgccatagcg gcgcacatta actgacttgt cctgcatctc cttatcacca
     2881 acgattaatt ggtaagggat tttactggtt tgagaggcac gaatcttata ttgcattttc
     2941 tcattacgat catccacatc tgcacgaatc ccatgatcac gaaggatttt agcaacctcc
     3001 caagcatagt caatatgggc ctcattggaa attgggataa ctgttacctg acgtggtgcc
     3061 agccatgttg ggaaagctcc cttataggtt tcaatcaaaa tagcagtaaa gcgctccatg
     3121 gttgaaatca ccccgcggtg gatcatcacc ggacggtgtt cttctccatc agcaccaata
     3181 tagctcagat taaaacgctc aggcagtaag aagtccagct gaatggttga tagggtttct
     3241 tcatttccaa gggctgtttt gacctgaata tcaagctttg gcccgtaaaa ggcagcctct
     3301 ccttctgctt caaagtaatc agcgcccatt tcatcaagcg cagccttcag catgctttga
     3361 gcattttccc acatctcatc gttatcgtaa tatttatgtg tatcctttgg atcacgatag
     3421 gacagacgga agcggtaatc tgttaggtta aaatcctcat aaacgtcaat aatcagctga
     3481 agagctcgct ggaattcctc ctgaatctgc tctggcgtca caaacaggtg cccatcgttt
     3541 aaggtcatct cccgcacgcg ctgaagccct gaaagagccc ctgatttttc atagcggtgc
     3601 atcataccaa gctctgcaat acgaatcggc agctcgcgat aggaatgcac atggttttta
     3661 taaacctgaa tatggtgtgg gcaattcatt ggacgaagga caaattcttc accatctccc
     3721 atatccattg tcgggaacat atcctcctga taatgctccc agtggcctga tgttttataa
     3781 agctcaactg aagcaagcgg cggagtataa acatgctgat agcctgatgc cagctcttta
     3841 tcagtgatat agcgctcaag cgtgcgacga atcgtcgctc catttggtag ccaaaatggc
     3901 aagccttgtc ctacctcctg agagatcata aacaaatcaa gctccttgcc tagcttacgg
     3961 tgatcgcgct ccttagcctc ctcaaggcgt gtcaaatagg ccttgaggtc ctttttatca
     4021 aaccaggctg tcccatagac acgctgcatc atgttattat cgctattgcc acgccagtaa
     4081 gctccagcta catttaacaa atgaaagacc cgaatccgac ctgttgacgg cacatgagga
     4141 ccacgacaaa ggtccacaaa ttcaccctga cggtaaacag ttaagccagc cgcatcatct
     4201 gcatgctcat taatcaactc aaccttataa gggtcatcct taaaaagctc aagagcctct
     4261 tcttttgtga tctcctcacg aatacatgga aagttctctt tgacaatttt tttcatttcc
     4321 tcttcaatgc gaggcaggtc ttcgttagag atttgaccat cagcattatc tgtatcataa
     4381 taaaaaccat ctgcaatggc agggcctaca ccaagatgca gcttggggaa caagcgctta
     4441 gcagcttgag caaacaagtg agccgcagaa tgacgcagca cctcaaaagc gtcctcatga
     4501 tcagcagtta taatttctat actaccgtcc tcttcaatgg cgcgcgtggt atcaattaat
     4561 tgaccattaa acttaccagc caaggccttt ttagctagag atttgctgat agagtcagca
     4621 atctcaaagg ttgtgacacc agattcaaat tcacgcaccg cgccgtctgg gaaagtgatt
     4681 gtaatcatct gttttctcct ataaaccatc tagatactta aaacaagcta atcaagcagg
     4741 gctatatctc ccaagccttc tgctgctacg acaaaataaa aactgactgc ctcccaaagg
     4801 acgcaatcag cgtggttcca cctttattta tgcatgacaa agaaatcctg tcctgcacct
     4861 cagcttggct atatcgtgac caccgtttta tgtttgcata aaagcaagga aggagtatta
     4921 cactagacac cctgtgctct tctcaccaac cagcactcgc ttaaaggatg cgacctaatc
     4981 taacttgtct tcctgattat tatagcaata tttggaaata attcaagtga tttttcctaa
     5041 aaaagctgag ataagcccac agacctccaa gcccacaagg caagaatgac taggcaagga
     5101 accctgaaac ttctgccaca agcctttgaa gaacagctca aacaggactt gccgcctgtc
     5161 gtctcagttc acaagacaac aaactaaatc ctttagacaa atgattatcc taaagagcta
     5221 tctgctctct cacgcagaac caaagcctgt aattgcaggc ttctttgttt atttagcctt
     5281 agtccaaaaa gtctcggatc gcattgacca gcttgatagg ggctttgagc accttgacag
     5341 atgtcagtgc agttgcctta gctgctcgct taggcaagtg aatcgctcct tgaaccagct
     5401 tgattgagcc actcttttct gttcgattga gatagagact tagctttttc gtctctttat
     5461 tgtgtcgcga aatcaaggta tctaaataaa aggtgtacac tgatttgcca aaatgctgag
     5521 ctgaaatctc atagcgcttc tcatctagca gcctctggtt catttgaggt gtttctaaaa
     5581 tggcatcaat aatcgcatct gacaattctg actcagcata ataaagtgtt ccaaacatct
     5641 tatcggtaat caaatcatct aggtagggat tgccatgagc gatgatgggc ttgccactag
     5701 caaggctctc aatataagtt agcccctgtg tctcactcgt tgacgctgaa ataaagaaat
     5761 cacaggcctt ataataaagc ccaacctgat catgagcaat cataccagta aagaccacat
     5821 gatcctcaac gcctaagctg acagccagct cctttaaggc ttgaagataa ggaccatcac
     5881 caacaatgac aagcttgatc ctgctatttt cactcaaaac agctggcagc tgatggataa
     5941 tagcctgaat attcttctca taagacaccc gcgacaggct caatagcatg gtctcatcat
     6001 cagaaatggc caattccttt ctcaaggcag cgacatcttc ttttttaata tcctcacgaa
     6061 catagttctc tagtgcaatg ccagtcggaa tcacacgctt aggaatggtt acctcgtacc
     6121 cttccaaaag atttagcaca atccgacttg ggcaaataac accatcaagg tcctttaaat
     6181 acccacgaag caggggcttg accatgctag gtcgaatgat cttaccatta gcaatatagc
     6241 tcacataatc ctcatactgg gtatgatagg tgtgaacaac cggaattctt aaggccttgc
     6301 ccaccatttt gcccaacaaa cctaagctaa actctgtttg agtatggata atgtctaaat
     6361 gatattcctt agcaatcttg taggaggaaa tgagcccacg ataaaccaca cgacgatccg
     6421 taaaggacac aaaaggaaca cttggtaacc gaataatggt cggatcctca aagcgcttaa
     6481 catgcttgtc tgttgttgtg aaaatataga cctcatgccc ctctttttcc agctcctcct
     6541 ttagggtgcg aatactggta gccactccgg aaacctgtgg aaaataggta tctgtaaata
     6601 gacctacacg catcttataa ctccattact ttttgataaa tagccactaa ttgatgagca
     6661 atcctatcaa ggctgcgccc ctcggcgaca cgatagccgg cctctgtttt gttgctttcc
     6721 cctgaaagaa tgcgtcttaa ggctgcaaca aagcctgagg tatcatttgc caactcagca
     6781 ctgtcttgat caatccagcc ctcatagact ggtatatcgc gtaaaacaag atgctgccgg
     6841 ctggctaagg cttcgagaac cacaatgcct tctgtttcct cacgacttgg gaagaaaaag
     6901 gcgtcagccc cagtcatagc cccctcatac acatctccct tgatataacc agggaagatc
     6961 acattatcgg ggtgcttacc gttgacaatc tggcggacac gagcaggaat aacccattta
     7021 ttggtatcac caaaccagat aaaccgaaca tctggcatca tctcagcaac cttaacaaac
     7081 tcatcaatcc cttttctaag aaagaaaagc cccgctccca tgactacctt ctcaccctct
     7141 ttgaggttaa aataacgccg aaaggcagct tctttgtcag cattagcacc atattgctcc
     7201 aaatcaatcc cattagatac tgcaaaaata ggagtcttaa ccccgtaatg ctcaatcaag
     7261 gctttagaat aaggggtcgg tgtgataatg gcgtccgcct tattgtaaaa gcggcagaga
     7321 taggctttga ataaaggaga cactagattt gaaaaaataa aggaatttct aaaatcctcc
     7381 tctgtcgaat gcccatgcat gatcaccttt ttaccggcct tttgagcctt tgacatcaaa
     7441 agccagcttt taagcccata ggtattgaga tgaaccaaat catagtcgtc ctttggatca
     7501 gtggtgaact cctgtcccac aagcgatagc gcttttgcct gatgcttaat cgctcgcccg
     7561 atacctgatt ttcttaaata attttctgct tctaaataca ataagacttt catactgtct
     7621 attatagcct attttatggt atttttcact aagagagtta aaaatcagcc cttagactga
     7681 ttttagggta aggcttcttc tacccctata ctcatctcaa aaatgctttt aagtcctgct
     7741 tttgctgtca tcaaatggct gatcttggta atatcagcta gaccaagatc gtgaaagctc
     7801 cagctcaagg ctcacgtatt agccctttca agaaagcctc ccacctttct cactggccaa
     7861 aaagccagca agacctggcc ttttcttctg attaattcag cctatcagct aagcttcttc
     7921 ttttggctgt gctttttgta acacccaggc tgagatagag cctgcctcta ccttgaaatc
     7981 tgcccagcca tcctcagcaa caacaacagt ctcctgacaa ttgtctaaga aatcacaaaa
     8041 aacttgacca gcataggctt gaccaacctc catgtgcttc cagcctgcat cgccattaga
     8101 caaaacaact gccaaaggct gaggacgctg atcatctcct aagcaggtcc agccgataca
     8161 attggcatga tcaaagtaat caatctgctc cccatagacc agctgctgcc tgagctctgc
     8221 catttttgtg ataacctcct taaaactttg ctgagggtag tctccagaaa taccataata
     8281 atcaccataa aaaagacagg gcttgccctc ttgtcgtaaa agaatcaggc cataggctaa
     8341 gggcttgaac cattcctcaa cagttgactc taaggcttgc cctctttggg tgtcatggtt
     8401 ttccacaaag gtaatagcaa ggtctggccg actagccaca agactgccat caaaaatagt
     8461 ggtcaaatca aaatcagctc cctgctggct agcattaaaa aaggacatgt gcagcgcaac
     8521 atcaactaga gcaaactgag ccttcgttgc ttcgaggtaa tcctccatag attcctgatc
     8581 agacttccag tattctccaa aaacctctaa atcgggcttt agctgggtac gaatatcatt
     8641 gataaaggtc tgaataaaat aagaatcaat atgcttcaca gcgtctaaac gaaagccctc
     8701 aataccagtt gtctcaataa accacttggc ccaatcctgt aaattttgga ttacctcagg
     8761 atgcttgaaa tctaagtcat tgtacattag ataatcaaaa ttaccatgct catcgtcaat
     8821 cagctcatca ttggcccagc ccttgttatc accggtgatc atgtaaatac ctgtttcatt
     8881 agccttggcg tcataatcca atcccgtaaa atggtaccag tgccatttaa agtcattata
     8941 ggtattttgt ctgccgggaa aatcaaagcc tgtccagcct tcaatctcat agggctctgt
     9001 aagggcctgc tgacggttct ctggattcat tttgatcaca gaaaagcgtt ccttgtgatc
     9061 accattagcc ttgtggttca gcacaacatc agcaataggc tttatttttg cctcttttag
     9121 ggctgcaatc agctgcaaat aatcctcttt gctgccatat tttgtgctga cagttccatt
     9181 ttggttaaac tctcccaaat caaacaaatc gtaaacaccg taccccacat catcagagct
     9241 agtgccctta aaggcaggcg gcagccacag ctgactaacc cctagctgtt gtagctcagg
     9301 aatactgctt ttcagccttt gccaatgcct tccatcggca ggcaaatacc attcaaaggc
     9361 ctgcattaat agttgatgac tcatcttaac ctcctaaaaa ggacaaacca gaaaactcct
     9421 agtttgtcct caaaactgcc taaacaggca gaactatttt gttgtcccac gctttttaat
     9481 gccatggttc aataaaattt ctttttcttc taattcttcc ttattcatga tcttagtgag
     9541 catacgcatg ctaacagccc ccaagtcata gaccggctgg ctgatagagc tcaaatttgg
     9601 acgtgtgtac tgaacgactg gagaatcatt gcttgtgata atctcaaagt cttctggaac
     9661 acgcttacca gcttcaaaaa gaccattcaa aaggcctgct gccagctcgt cctctgcaac
     9721 ataggcagct gtcgctccgg aattgatcac acgctgagcc agctcaaagc cttccttata
     9781 agaatagttg gcctcaaaca ccagaccctc tttaaagtca agcttgttct tcttgagtcc
     9841 gtccttgtag ccagctaaac gcacctttcc gttgatatca tcaatgagcg gccctgaaac
     9901 aaaggcaatg ctttggtggt ctttagctaa aatatccacc acatcagcaa cagccgcctt
     9961 ataatcaatg ttaacacttg gcagctgatg atccagatca accgttcctg ccagaacgat
    10021 tggcgtacgc gaacgagaaa actctgcccg aatcttgtca gtcaagtgat gtcccatgaa
    10081 aataatgcca tcgacctgct ttgcaaagag ggtattcaca acattgacct ctttatcatc
    10141 gtcctcatca cttgaagcaa gaacaatatt gtacttgtac atagcagcaa tatcatcaat
    10201 tccctttgcc agaatagaaa aatagctatt tgcaatatta ggaatcacaa caccgactgt
    10261 tgttgtcttt ttacttgcaa gaccacgagc aacagcattt ggacgataat cgagacgatc
    10321 aataacctct aagacctttt tgcgggtatt ttcctttaca tttttgttac catttacaac
    10381 tcgactaact gtcgccattg aaactcccgc ttcgcgagca acatcataaa tcgtgattgt
    10441 atcatctgta ttcattcttc atcttccttt ctaactgaaa atgacgcttt caaaaagtat
    10501 tttagcatga tttgtaacca ctttcaagta ttaacggttg atttttgaaa aagttttcaa
    10561 aaattcataa taagcttgct tttttaagta ttttttggaa aaatagaagg cagaaagaag
    10621 gtttatctat gactaaatta gatcaaattc gtttgtacct taatcaggaa aaggctgagc
    10681 ttgctatctt ttctgattct gtaacgatca attacttaac tggtttttta tgtgatcctc
    10741 atgaaaggca gatgttccta tttgtctatc atgacaaggc tcctgttttg tttgtaccag
    10801 ctttagaggt tgcaagggct gaacaattgc tggacttccc tgtttttggc tacgttgact
    10861 ctgaaaatcc ttgggaaaaa atcaagtctg tcctaccaag cacagcagca aagaccattt
    10921 acgctgagtt tgatcatttg aacattacca agtttcaagg gctgcagagt gtcttttcag
    10981 gacgctttga caatctaacc ccttacattc aaagaatgcg gctcatcaag tctgctgacg
    11041 aaattcaaaa aatgctgatt gctggagaat ttgccgataa ggctgtcaat gtgggctttg
    11101 ataatatttc acttgacgtc accgagacag atatcatcgc tcaaatcgaa tttgaaatga
    11161 aaaaacaagg catcagcaag atgagctttg aaacgatggt tttaactggt aacaacgctg
    11221 caaacccaca tggcattcca ggaaccaata aaatcgaaaa caatgccctg ctgctctttg
    11281 accttggtgt tgaaacatta ggctatacta gcgacatgac gcgtacagtt gccgttggaa
    11341 agccagacca atttaagctt gatatttatc agctttgctt agaggctcag ctaactgctc
    11401 ttgatatgat taagccagga gtgactgcag ctcaggtaga tgccgctgct cgccaagtga
    11461 ttgaaaaggc tggctatggc gactacttca atcacaggct cggccatggt atcggtatgg
    11521 acgttcacga atttccatca atcatggctg gcaatgacct gattcttgaa gaaggcatgt
    11581 gcttctcagt tgagcctggt atctatatcc caggcaaggt tggggttcgt attgaggact
    11641 gtggtcacgt aactaaagac ggctttgagc tcttcaccca aacaccaaaa gaattactat
    11701 actttgaagg gtaataggag gcttaaaaag cctgaaacaa aatgtctcag accctaatat
    11761 ctaaagcaac agcacttggt ctgttacttt tcatattaca ggctattttc tcacaaggaa
    11821 aagtcaaagc accccttgat gggaaatcag aggggcaaaa gctatttgta ctaagctcaa
    11881 aagctaatca agagcacctg accagctctt tatcctttaa gtgataaatg caatcataag
    11941 actgtgcatt atatttatga gctatctcaa ccatggtgca ggggagtgaa tggagtaact
    12001 cacgaatctc tctggcgctt tctttgtcta gggcagctgt gacctcatca gccagcaaaa
    12061 tcggttttag tatcagcaag cagcgtgcaa tttccagctt catgatttgc ccgccagaga
    12121 gattttgccc atctagatgg agatcaagat ctccgtttag ctcattccaa agatgaacct
    12181 gctgtaatat ctcctttagt cgctggtccg aataatcctg aaacagcgtg agattatctc
    12241 gcaagcttcc ttcaaatatg taaggctttt gatgtatcaa agacacaaca tcataggaag
    12301 gaaaatagcg ttttccattg gcagcttcaa aataaatagt tccagaataa tccttatcct
    12361 caccacacaa aagagcaaat aaagtagatt tcccactacc actggctcct gttagcaagg
    12421 ttttgtgccc tgctgaaata tgaccatcta tcccttgaaa aataagccta tgatcaaaat
    12481 acttatctaa cctcttaaag tagatatcaa gtgtaagatc atctgtaggg gttaaggctt
    12541 gatgttttgt ctcttcctcc agagccaata ctctaaccat cttctcctta acagcagttg
    12601 cagactgtaa actcgaagta gcttctaata attgctgcaa gggagagaca agattcgtag
    12661 aagctgttat catagcaatg agagttgtta gtgatagact tgaatagctc atcaccaaca
    12721 gaccaataat aagaggacta accaagccaa tcccttttaa tggaccagtc caaaacatta
    12781 ccagattgtg ggtagtataa tagctatatt gcttgtcttc catatgctga atcatttcta
    12841 acacatggtg agcaaaagct tcgttggctt gattactctg tatcgtgtct gcccccttag
    12901 taaaatcggt gatactggct aggcttttct ccctcgcctg actaagctct aagcctcgtg
    12961 attgaagtaa gtgattgaac acaaactgtg gaataatcat caaaaagcca ccaatagtaa
    13021 aggcaatacc aatataaata tcctgcaaaa gaaggtacaa gacagaggct aagatagata
    13081 ggccaaaaac aggataaatg aataagggga ccaaatactc ctgccaaaac ataggaatat
    13141 cttgggtcaa aaacgaattt aaggctgaag taaaatagtt gagctgttta tgataaaaat
    13201 gatataaagc cttctttgca ataaggcaat taaacgctct aaccatagaa cgtgctaaaa
    13261 tgttattaag atacatgcac atataaataa agacaaaaaa agctacgcct ccaagaccaa
    13321 aaagcaatac cattccttta ttgttcatat caatttgccc tgctatctga attaatactg
    13381 ataacaatag tccctgcaag gaatagagca aagccaataa actatacaag caaagctgcc
    13441 attttgaaat gacttgtaaa atacttttca tatcaatcac tcctcacctg aaacctaaat
    13501 gtatcgctct cttggaaagt ataaacgaaa catcctcata caccaatcat ttccaccaca
    13561 aactagattc ttgaatgtta aatcaagctc ttgatcaaaa tcatgttctc tgatttcttg
    13621 aacaaccatt ggttctctcc tttcattctt actatttcta gtatataatg ggaaaaaata
    13681 cgaaaggaaa aatttcggaa atccggatat gaatatcaga gagaaattta aagcaattcg
    13741 taaacaaaga agactatcct taaaaacgct tggtaaaata gctggctcag ccactagtat
    13801 ttctgacttc gaaaatggaa aaacgaacct ttctaatgat gttttattgc agcttttagg
    13861 ctttatgatt gttgaaataa acgagctatt cgaatgggag gattttcacg aaaaggaatt
    13921 ggttgaagcc atcaagcaaa tcgaactggc aataaaatct aaacatattc ctgctctatc
    13981 tcagctacag caggactttc aaagcttatc taagacaaag gaacagtaca tttaccacat
    14041 catctcactg atcctaacca tcaccattgc agaatatcaa aacaaagaga tcgatccaca
    14101 catcatgtct gagctaacag actacttctt tttcttggag tattggacta accttgatgt
    14161 cggcctacta ggaaacatcg tccactacat gacaacagat gccctaatct tattgacaaa
    14221 tgacatctta gagcatacgc ctcaagtact ccgaaataac ctagatcgta ttaggatcga
    14281 tactgtatta aactgtctta ctgtcttgat taatcgtaaa gaggagaagg caagcagaac
    14341 acttcttaaa ttattattta acaaacatta tcctaattac tttgcctttg aaaagctcta
    14401 tttacatgaa ttacaagcag tctatgattt taactggaaa gataaagaac aggcgcttgc
    14461 agctcatcac gtcatactgg ctaccatttc attactattt acagctgatg aagccaaaga
    14521 atgggacagc ttctttcaag aaagtactag ctctttgtaa tactccagct catacactaa
    14581 agaaaagcaa ggataatcac ataaaaacta atcacatcac tttgccctgc tagctgaatt
    14641 agcttgggtc atctcttatg cccagcaaaa catcatctag tctcagcttt cttccaaagc
    14701 ttcttgtctc tctgggcttg caagcttttg atagcttaag aggcacaagc attaacaaag
    14761 gctaacaaat gcctgtaaaa atatgctatg ataggggtaa caaaaaccta ggaggtgctt
    14821 atgtcacaca aatccattca tcaacagctt agaaatgctt tttcctttcg gacagcggta
    14881 cgcgtctaca atgaccaaaa aatagccaaa gaagacttag acctgatttt agatgctgcc
    14941 tggctcagtc cttcctctat cggccttgag gcctggcggt ttgtcgtttt agaaaacgaa
    15001 gctgtcaagc atgagctaaa ggaggtctct tggggagcag tttatcagtt tgagacagct
    15061 agtcatatga tccttttaat cagcgaaaaa aacgccagat atgatggcgc ttctatcaag
    15121 caaagcttat tgcgcagagg cattactgac gagcaagcct tggccagtcg tctggcatgc
    15181 tacgaagcct tccaaaagca tgatatgaaa atagcagatg atcctcgggc tctctttgac
    15241 tggactgcca agcaaaccta tatcgcgctt gctaatatga tgaccactgc tgcttttatg
    15301 gggattgact cttgtccgat tgagggcttt aactatgaca aggtaaatgc tatcttagca
    15361 aaacatggga ttatcaaccc tgataccgag ggtatctcta gcatgctgtc tttaggctat
    15421 cgcctgcgcg atcccaaaca ctcacaaacc agaaagccca gagaagaggt tatttccttc
    15481 tttaactaag ccccttttgc cattgctccc aaagaaagtg caaagacagt cctttgcctt
    15541 ttctttttca taactgtcga attatggtac aatgtgtcaa aagacctatg gaaagtgatg
    15601 cctatgacat tattatctgt aattatcccc tgcttcaacg aagaagacac gattattcct
    15661 tatcttgaag aaatgaagca aatcgaagcg gccatgacca gccaattagc ctttgaatat
    15721 ctttttattg atgatggctc tacagatcaa accctgagcg tgctaagaga gcttgcgggg
    15781 cgcttctcta atgtgcatta cctctccttt tcacgacatt ttggcaagga agctggacta
    15841 ttagccggcc tagaagaggc aaaaggaagc tatattacgg tgatggacgt tgacctccag
    15901 gacccacccg agcttctccc gctgatgtat agcaaattac aggagggctt tgatgtggtt
    15961 gccacaagaa gacagagccg acaaggagag cctgctatcc gttccttttt tgctagactc
    16021 ttctacagat tagtcaagca tgtctccaac accgaaatcg tcgatggggt acgtgattat
    16081 cgtttaatga caagacaggt ggtggatagt attttagagt tgggagaggt caatcgcttt
    16141 tccaagggga ttttttcttg ggttggctac aatactgcct atatcagctt tgacaatcgt
    16201 aagcggcagt acggcaaaac cagctggaac tttcttgagc ttttgaacta ctcgatagac
    16261 ggctttatca atttttctga gatgccctta accattgcta cctggactgg gacacttagc
    16321 tttttgctat ctctgctagc catttgcttt attgttatac gcaagctgct ttttggtgat
    16381 ccggtttcag gctgggcaag cactgtatcc attatgctat ttatcggtgg aattcagctg
    16441 ttttgcatgg gaatcattgg aaaatacatt tccaagatct tccttgaaac caagaaaaga
    16501 cccgtctaca tcatcaaaga aaagaaataa cagagcaatc atcaaggccc ctatcagccg
    16561 ccaatgaggc cgataaggac tggttgccct catcatgaca agcacgacaa aaagacttga
    16621 tggtcccaat caaaaccatc aagtcttttt tagtatgtga ccttgcgtct gcctcgcacc
    16681 taaaaagacg agataatgtc ataaccaccg tctatctact gaccccaaaa agttggacaa
    16741 tttagtttta agcaagggat ttagttctgt attgcacagg actaagcaag gccatcagct
    16801 tgtaaacaga cgcttagcgg cggttcacac tcttcatcac acgccgaatg tcacgatcct
    16861 gctcgcgtcg cttgatcgat tcacgcttgt cataatcatg ctttcctttg gcaaggccga
    16921 ttaacacctt ggcaaagcca tccttaagat aaacctttag aggaataagg gtcattcctg
    16981 tgccctttag ctcatctgct aggtgctgaa tctcacgctt tttgagcaat aatttgcgcg
    17041 tgcgctccgg atcagcattc cagatatttc cctgctcaaa gggagcaata tgaacattga
    17101 ccaaccaggc ctcaccattc ttgatttggg caaagccgtc cttgagctgg atacgcgcgg
    17161 cacgaacact cttaatctcc gtaccggtca acacaattcc agcctcaact gtctcaacga
    17221 tatgatagtc atgacgagcc tttttgtgtt gcgctaatac attaccttca ccttttgcca
    17281 tgcttaactc cttttacgac ctttcttttt agcagctttt tggtaaaatg gtttctttgc
    17341 tttttttctt gtcttctgct ttgattttgg ctttgagggc ttggactcct tactcctgct
    17401 agcccttgaa gcagcctttt gcctgtgctt atgcttagct ttagctgacc ttgtggtctt
    17461 ttcaaccaca tcatagtcac tagccaagta atcaaaatca atgtcacctg tttccttgtc
    17521 agccctcacc aatctaaccc gaatcggctg acctgctcta aatacctttc ctgagcgttc
    17581 accctttaag gagagtgtcc gttcattata gtgataatat tcaggcaaat tggtaatatg
    17641 caccagacct tcaattgtat ttggcaattc gacaaacatg ccaaacttaa ccacactagc
    17701 aatcacgcca tcaaacacat caccaatata atctgccatg tattctgctt ttttcatcgc
    17761 ctcaaccaca cgctccgcgt caattgcacg acgctctagc tgagatgacg atactgccaa
    17821 ttctggaata acctgtgcaa aatgatccac cttctcctgc gtgatctgat tgtattctcg
    17881 aatcatgcgg tgcaccagta aatcagggta acgacgaatc gggctggtaa aatgcgtgta
    17941 gtagtctgct gctaagccat agtgaccatg attatgctca gaatacctag cctgctgcat
    18001 agagcgcagc agcatcatat tcaaaacctc tgctccagga cttccttcta cctttgccat
    18061 aaaggcctgc aaggcttctt gagaaatctt attagcagtt ccctgaatct gaatcccaaa
    18121 ggcactagcg taatcaataa aggtctgcaa tttctctgcc tttggctcct catgaacccg
    18181 gtaaataaat ggcaagccag cccttgaaaa atgctcagca acacattcat ttgccgctag
    18241 cataaaggac tcaatcatgc gctctgcaac acctcgctgg cgcaagacca catcaaccgg
    18301 catgccctta tcattgacaa taatcctagc ctcctgcgtg tcaaagttca aggccccgcg
    18361 cttcacacgc atcgcctcta agatctgatg cagctcaacc atagtactca catcatcagc
    18421 aattctatca aattccctaa gcgcctcact gtcacctgca atcatctgat tgaccgcgct
    18481 gtaggtcatt ctaaaggttg tgttaatcac tgactgacac agctgataat caaccacatg
    18541 tccctgatga tcaatctcca tgatcgctga ctgggtcaac cggtcaacct ttggattgag
    18601 agagcagata ccatttgaca accgctccgg cagcattggc accacacgat ctgtcacgta
    18661 aacagaggtc ccgcgcgcag ctgcctcacg atccaaggct gacccttccg tcacatagta
    18721 ggacacatct gcgatatgaa ccccaagctc aacgtttcca ttggccaatc tcttgatatg
    18781 gatggcgtca tctaggtctt tagcatcagc accatcaata gtgatggtcg tttctttgcg
    18841 caaatcaaca cgccccataa gatcctgatc actcggagca tctggaatgg cattggcctc
    18901 agctagaacg tcatctggaa acgccgatac aatatccata gattccaaaa cctccagcac
    18961 atcaatgccg acatcatgct gatgcccaat aatatcacac acagtcccta caaaataatc
    19021 ctgcccagcc ttagggtatt gcacaatatc agccttaatg atttcagtac catctaaggc
    19081 aattggagat tttgcgatat aaatcctctg ttgaatcctt tgatttttcg acttgatgta
    19141 gccagcatac ttagggtgat catcatctaa aataacccta ccaacaaccg tctttaaaga
    19201 gcgctccacg atagctacca cgcgagcctc tgctgctgta gccttaagcc gattagctgg
    19261 ttttttaata acagcctcaa ccctatcgcc atcactagca taccccacat catcacgacc
    19321 aataaaaatg tcgtcctcat tgtcatcaac cgacaaaaag ccaaagccag ccttattggc
    19381 acgaaaaata ccttgaaccc ttatctctgg ctttttttgc tgtggtgctc taagaaacac
    19441 ctcaccctca tctgaaaaag acaaaagtcc cttgccttcc attttggaaa tggctttaat
    19501 caggcgagga aagctccccg catcagtcat ctctagtgca gccgccaaat catgaatatt
    19561 tgattggcca tgctccttta aataattcgt aatgttctct atcatcatac ctatcttcta
    19621 tttctaacac catacttgat ggttgtgctc attgataaaa aaatgagcta gactaactct
    19681 gtcaagctca ctccttattt acttgataaa atggcaagca ctaacgcaat tcctaaccaa
    19741 aaaaacacta gaactgctgt aaaacgttgc ataaaagctt caaatccgcg agcttttgta
    19801 cgctcaaaca aggcttctga gccactgcta tcaaaaacat tgctactagg atttttttgt
    19861 ggctgcataa agatagcaat cacaagcaac actgataata ctagcaatat cgtaagtagt
    19921 aagtcgtaca tgttaattcc tccactgtag tctcaatcat tctaacacaa aaccaactaa
    19981 gattcaacat gcagcgttac ttttctctcc ttaggacagt atttaggaac cttaatcttc
    20041 tcagggtgac ttgttttatt tttactagtc aaataatttt tgctgccgca atggctgcac
    20101 tccaaatgaa tctttactct cacatcattt ccctaatctt actatatttt atcagcgtca
    20161 taaggcttca aatcacccgc agcttcttta ttaaagatat ctctagttat tatagcatat
    20221 tatccagtaa gaaaacaaac tcaggacttt tagcaaaaaa ggcttaagcg ccaaccaata
    20281 aacattccaa ggctatcggg gaatattttc taatggttat tataaatcat gaacaattac
    20341 ctaacaaagc aactccaaaa caaagataaa agacgaacat tcaccttgct gctcagctat
    20401 caagataaac aatcctgata gcatcaattt tctttaggtc ctcagcaatc ggttgtaata
    20461 tcagacaatt caggtgttga ttaaaaaaaa cgaaactacg gagaccaatt gtcagaaagc
    20521 tattcacagc ccgcaggcgt cgtgctaaag tattgtctgg aaaaagaaag gtttaggaat
    20581 gattatacct aaactcaaag gagagaaaca atgagaaaaa caatgaagaa gatgctagca
    20641 gcctcgacgc tctgcatcat catgtcaggc agcttcatca gcggctcagc tagagtgttg
    20701 gcggagaagt attatggttt taatgatggc acaggagagc attcaccatt ccctgtatac
    20761 gttactccaa ttactaaacc taataggaat actgccaaag ttgtctactg tttcaataaa
    20821 gatatgaagt ggccagaaac ttgggataaa gcagcaccaa aaaaaccaga taatttacct
    20881 ctatactacg atatggaagg tactgatcaa ttattcagta catatgcaag tggacaactt
    20941 actcctaatg tcagtaaagt cttagctaat ataatggcta aaggttatcc aaacaacaat
    21001 gagtttgctc accattttaa actcactccc aattccgctg taaaagttac tcaaatcgca
    21061 gtttggactg ttacggataa cctaaaaaac tattctcaat acagtctaac cagagaagag
    21121 gaagctgcat taaattacct aactgacaaa aatggggacg actttagcga tagtatcaag
    21181 ttaaaattat acattccaca aaatcctcga actataaaat atcaaaatct tctaggttat
    21241 gacctaatag ttaaaactcc agaaaaaaaa gataattgta aatgcaccaa aatttatata
    21301 gaagataatg gaaaagatgg ctattatctg tatatttatt atgacaacaa tgaaaataat
    21361 agatatgact cggacaaaga tagcctattg caaaagaaat acataaaaaa tgggaaagat
    21421 gggaaaccag gaagaccagg ggttccagga cttcctggcc ctgctggacc tcaagggcct
    21481 agaggagaca aaggagaaac cggggaacgt ggacctaaag gtgaaaaagg tctagacggt
    21541 aagcctggtg aaaagggtcc taaaggcgat acaggaaaag atggtaagga cggacaaccc
    21601 ggacctcagg gacctaaggg tgaccctgga cgtgatggaa aagatggcga acctggaaaa
    21661 cctggcgagc gcggtgagaa aggacctcaa ggcgaacgtg gacctcaagg acttcctggg
    21721 cccaaaggtg agcctggaat tccagggcct aaggatgaag atggaaaaga tggtgctcct
    21781 ggacatgacg gacaaccggg gcctaaaggt gaaaaagggg accctgggca acaaggcatt
    21841 ccaggaccta aaggggaacc tggacgtgat ggtaaagatg gagaaaaagg cgagcgtgga
    21901 gagcaaggac ctcaaggcga acgtggagag caaggacctc aaggcgaacg cggagagcaa
    21961 ggacctcaag gcgaacgtgg agagcaagga cctcaaggcg aacgtggaga gcaaggacct
    22021 caaggcgaac gcggggagca aggacctcaa ggcgaacgtg gggagcaagg acctcaaggc
    22081 gaacgcggag agcaaggacc tcaaggcgaa cgcggagagc aaggacctca aggcgaacgt
    22141 ggagagcaag gacctcaagg cgaacgtggg gagcaaggac ctcgtggaga aaatcctact
    22201 cctaccccag atccaatgcc acaaccagaa ccacaaccag aaccacaacc aatgcctgat
    22261 ccagcaccta aaccagaatc caagccagaa cctaagccga tacctcaacc agaggttaag
    22321 cctcagccag agacaaaacc tcaacaacca aacaagccat caaccattac tagccaatct
    22381 agcggcaaat cactgccaaa aacaaatgac actggcagct tgatcacagc atttggtaca
    22441 ggcttactca ctcttcttgg actaggcttc ctagcaaaac gcaaaagaaa gcaataatta
    22501 aaacactacc catagccttt taatcattgg ctatcaacta gataacaaaa agcttatcgt
    22561 tttactccta acgataggct ttttcgcatt ccctattgct tggtctcaat actatttttc
    22621 cagctttagg ctggttttgc taatccaaaa taatatcaga caatttccgt tttaattaaa
    22681 aaaaaaaaaa aacgaaacta cggacgccaa ttgtcagaaa atggttcaca gcttagagtc
    22741 accatgttaa gctattctac gaagaagaaa ggtttaggaa tgactatttc taaactcaaa
    22801 ggagagaaac atgagaaaaa caatgaagaa gatgctggca gcctcgacag tctgcatcat
    22861 catgtcaggt agctttatcg gcggatcagc cagaatccta gccgagcagt attatgggtg
    22921 gaatgatgga acaagagtaa aatcaccttt tttcctttat gttacgccaa caaatgaaac
    22981 gactaggaaa accggaaaaa atggtacaat agtctattgt ttcaacagag ataaggaatg
    23041 gccagcaaat tgggaagaag gaagatcctt agaactagtg aatgctgaaa cagcttataa
    23101 attacccatc tataataaat tactaggtac aactgattcc tttactaaaa atgctagtaa
    23161 accaagagta tctggagata ttggtaaagc gctaatagct gtactgaaaa atggttatcc
    23221 taataaaaat ttatccggat tagatgacac taaaagtcga atactaactc aactagctat
    23281 ctggtatttc
//
LOCUS       DARYXS010000027        22142 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.027, whole genome shotgun sequence.
ACCESSION   DARYXS010000027 DARYXS010000000
VERSION     DARYXS010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22142
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.027"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(93..464)
                     /locus_tag="TV193_000840"
     CDS             complement(93..464)
                     /locus_tag="TV193_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513057.1"
                     /translation="MKLRRKTRLTKIGAPMTVNIGKSHKVKLYPGESIDIDLPDAEDY
                     LTIKHSRQAKKIVTNQDQVTITDNPINLILFWSGVVLVLGSHLVLSFDSSWLYWLTII
                     GLSSIIVSYLVPRFKWVVTQS"
     gene            683..1321
                     /locus_tag="TV193_000841"
     CDS             683..1321
                     /locus_tag="TV193_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL1513058.1"
                     /translation="MVKGIIFDMDGVLFDTEPFYLKRREAFLTSKGIRIDHLSPEDFI
                     GGNLQQIWDKVLAGQANADEARDIAVAYEAYKLCHKPPYQELMFKGVKSCLKALKGQG
                     LKLALASNSSRCDILLALESSHIKAYFDLTLAREDVTAGKPNPEIYNKVAQALGLAKA
                     EFVVVEDSQKGIAAAKAAGLKVLAIKDKRYGIDQGQADKRIDSLRQLCELLR"
     gene            1517..2053
                     /locus_tag="TV193_000842"
     CDS             1517..2053
                     /locus_tag="TV193_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1513059.1"
                     /translation="MLSLLIGGLMAVKLLTERLIIQELNETYFEPYHKAFTEEITAFQ
                     WPDPFKDIAAAKETLASFIAEMKKGNMLELVILNKANDFVGSLEVFSLDSETPELGIW
                     LKKSSQGLGYGYEALRAIVDYLKGKNKYRYFNYEVDVRNTGNIKLVEKFNVVTSTYQE
                     CETASKKRLCLQVYHILN"
     gene            2916..3320
                     /locus_tag="TV193_000843"
     CDS             2916..3320
                     /locus_tag="TV193_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEL1513060.1"
                     /translation="MTEIPKDLKLNTISVFEHYHIDVFEAGHVLLSTEIHASALNYYG
                     NAHGGFLFTLCDQVGGLVAKSIGLEAVTLQANVNYLKPGHLGDRLVVEGSLVHRGRTT
                     QLIEVTIKNQDDRLLTRVSLTMFVTSKKRSSD"
     gene            complement(3376..4860)
                     /locus_tag="TV193_000844"
     CDS             complement(3376..4860)
                     /locus_tag="TV193_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEL1513061.1"
                     /translation="MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKILEDFHA
                     ARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTF
                     NALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPDGMG
                     RNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLKGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASRQEIIRRYYQTLVDFKAERVTEAAVKKLELLMND
                     IGVTPKDRQVTLIARQKAEITGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTL
                     AHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKE
                     LGNLKGSEAHSTVILTNEDKHVLRQLGINVTFDPVYQHHKLYRS"
     gene            5219..6442
                     /locus_tag="TV193_000845"
     CDS             5219..6442
                     /locus_tag="TV193_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1513062.1"
                     /translation="MSALSLDKNNKRALWAAIAASGTDDLNVMFLAFSMSSIISDLGV
                     SSTQGGWIATITNLGMLFGGLLFGLLADRHHKFKVFKWTILIFSVATGLIYFTKTIEF
                     LYLMRFIAGIGVGGEYGVAIAIMAGLVPAEKMGRVSSLNGIAGQVGSIVSALLAGWLA
                     PALGWRGLFLFGLAPILLVIWMMVAIDDDKIIDNHVNVSEEASQPVKISELFKTPALT
                     GQTLALMVMTTVQIAGYFGMMNWLPTIIQASLHISVKDSSLWMVSTIVGMCLGMLTFG
                     HLLDTFGPRLVYSIFLLLSSVCVYLFQFANSMSTMLIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNLILNVGRAVGGFSSVIIGKILDVSSVSMVMLFLALLYLVSFVALW
                     TIKNLKAERYQALTK"
     gene            complement(6532..6891)
                     /locus_tag="TV193_000846"
     CDS             complement(6532..6891)
                     /locus_tag="TV193_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEL1513063.1"
                     /translation="MSIYSQLYETKSKHSAQAMGSGGLEVLATPALVAFMEHAAFTFL
                     QSQLKDKQTTVGSEIAIQHLAASKIGQAVTIVITALKEEGRKYDFRIEAFANHKLIGR
                     ACHTRVRVDQDAFLEKL"
     gene            7056..7775
                     /locus_tag="TV193_000847"
     CDS             7056..7775
                     /locus_tag="TV193_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1513064.1"
                     /translation="MRLDKFLVDAGLGSRSQVKLLLKKKQVSVNGVSQTSPKYQVNEM
                     TDEVSYQGQRLNYEAFVYYMLNKPKGVISATEDSSHKTVLDLLDDTARQKAVFPVGRL
                     DKDTHGLLLVTNDGKLAHALLSPKKHVAKQYLAVVDGMMTQEDVKHFAQGITLKDHQC
                     MPAHLDILEINESLKTSLVKITIEEGKFHQVKRMVAACGKTVSDLQRISMGPLQLDSA
                     LAPGAYRRLTAAELEAGWVSC"
     gene            complement(7820..8647)
                     /locus_tag="TV193_000848"
     CDS             complement(7820..8647)
                     /locus_tag="TV193_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEL1513065.1"
                     /translation="MVLPHFDDYLEKYANLLIKKGVNIQKGHTLLISIAVEQHKLARL
                     LTKKAYEAGAAEVLVDYNDDQITREKLLKADEDRLLQVPDYVVEQSHYLLDQKASRLV
                     IRSANPNVFADIDSDRLAGATRATAIALEKQRAATQANKVSWNLAAAAGPEWAAMVFP
                     NLTSEEEQVDALWDAIFKMNRIYETDPVKAWDQHQERLEKKARLLNDYQFDSLHYRAP
                     GTDLRLGMPEQHIWEAAGLNRSTAHADFMIGSEQMDIDGITKDGEVIPIFRGGEWAI"
     gene            8908..9036
                     /locus_tag="TV193_000849"
     CDS             8908..9036
                     /locus_tag="TV193_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEL1513066.1"
                     /translation="MAFGENGPRKKTAFEKLTTVVVIVMVLVTVGGLIAGALSVLM"
     gene            9090..10403
                     /gene="obgE"
                     /locus_tag="TV193_000850"
     CDS             9090..10403
                     /gene="obgE"
                     /locus_tag="TV193_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEL1513067.1"
                     /translation="MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFKVDEGLRTLIDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAET
                     GKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGL
                     IKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLME
                     RPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPIIFPISSLAHQGLDSLLEATA
                     ELLAKTDDFLLYDEADLAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTN
                     LERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD"
     gene            10524..10682
                     /locus_tag="TV193_000851"
     CDS             10524..10682
                     /locus_tag="TV193_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513068.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     DKLKKDEA"
     gene            complement(10735..11439)
                     /locus_tag="TV193_000852"
     CDS             complement(10735..11439)
                     /locus_tag="TV193_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEL1513069.1"
                     /translation="MAYLNYFTKTEWTLWLTSISAILLSAFFFGEQAPLALIASLIGV
                     TALIFSAKANPIGQSLAIIFSLIYAYLSLLNSYYGELITYLFMTLPMAILSLFTWLSH
                     PFEDQTSQVTISRLTTADRLRLVVLTILVTSLFYAILAYLKTAYLPVSTLSIATSFSA
                     AYLSYKRSPYFALAYALNDLVLILLWLYAAQANTSQYAVVICFAAFLVNDIYTFFNWL
                     HLQHHQEKKHQKRTKP"
     gene            11774..13174
                     /locus_tag="TV193_000853"
     CDS             11774..13174
                     /locus_tag="TV193_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1513070.1"
                     /translation="MKQSKRRYQFPEGFLWGSSTSGPQSEGTVSGDGKGPSNWDYWFS
                     LEPDKFHHQIGPEVTSTFYTNYKSDIALLKETGHTAFRTSIQWSRLIPEGVGQVNPKA
                     VAFYREVFQEIMAQDIKLIVNLYHFDLPYALQGKRGWEAKETVWAYETYAKTCFELFG
                     DLVDTWITFNEPIVPVECGYLGHYHYPCKVDAKAAVQVAYHTQLASSLAIKACHELYP
                     KHRISIVLNVTPAYPRSDQPEDVKAARIAELFQTKSFLDPSVLGVYPEELVVLLEAAD
                     LLPQYSADELAIIKNNPVDFLGVNYYQPLRVQAPSKTRQDGEPITLASYFEPYDMPGK
                     KVNPHRGWEIYEQGLYDIALNLKEHYGNIDWLVTENGMGVEGEEAFLVDGQIQDDYRI
                     AFIEDHLIQLHRALEEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLETQKRTLKK
                     SGHWFKTLSQTNGFDK"
     gene            13184..14278
                     /locus_tag="TV193_000854"
     CDS             13184..14278
                     /locus_tag="TV193_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEL1513071.1"
                     /translation="MVTLGFSLYPERHGFAKSKAYIDLLHCYGAKRLFMSLLQLAPND
                     PKTFKFYADLIAYANCLGIRVIADVSPAFIKQAGWSDQVIEEAHAFGLAGLRLDEALP
                     LEDIVRLTKNSFGLKIELNMSTDKSLLTALLKAAPDRSNLIGCHNFYPHAFTGLSLEH
                     FKEMSHFYHEHGIATAAFITAQSAKEGPWPLSEGLPTVEAHRQLPIDVQVELMKATGT
                     IDTVILSNQFITEDELVQCRQALDRSVMSIKVKPLVDLTDIEEKIICYPHCYRGDVSD
                     YVIRSTMPRVVYAQEAIAPREQPKQVKRGSIIIDNDRYNRYKGELQIALKAFTLSSKA
                     NVVANIKEDYLSLLDELKPWQEFSLVIETD"
     gene            14384..16378
                     /locus_tag="TV193_000855"
     CDS             14384..16378
                     /locus_tag="TV193_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1513072.1"
                     /translation="MLSKKEMAIVAFLISQKGQFVSSATLAKAIGMSDRTVRKYLKEL
                     ISSLPSKGAHIISKQGQGYCLEIDHSMAFEIFWQESLASKKRLADVTQVEETVDREHY
                     LLNKFFFEEPVWDFEELCQELYISRTTLNHVLAVIRDRIRPYQLQLDVSHQRVQVTGK
                     EEAIRHFIMDYFFATSFDDSMYAIVDNTFLDHIKFADITIIVLDECRDAKLKLSDFVM
                     HNLVLHIALMVQRIRSGYPLAFFSIPAAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVDGSPQDNKADDLLRSHLKAGIVKASQLTGMSLEADSSLLQGLLAH
                     MKPLATRLENHIQLTNPLTEEIKSKYPEAFALTKQAFENIPELQAYDLSDDEWAYISL
                     HIMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRFQIVDVISYYEITQER
                     LQTVDVIISSISLANVMFLTPVITVSVFLSDQDIKAIRQFIGEQEGIRREAASSSQMS
                     LEKAEQILKGVFSPKRFLYVKEKLSKKALLLKMIACLDEAMDEAFVEAFYHQIVLREN
                     YSSIVFGEVLAFPHPANPMTYSEQVVVAVCQEPIDWDESHRAVHFIFLLSPSKGRNSY
                     LKYISPSLVSFVNQAELQQALLEEPSYAQFITLFTPLITE"
     gene            16392..16709
                     /locus_tag="TV193_000856"
     CDS             16392..16709
                     /locus_tag="TV193_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1513073.1"
                     /translation="MKTIMLVCNAGMSTSMLVTKMQKAAQARGIEVEIWAVPVSEADN
                     EVAAKTIDVLMLGPQVKFLLKDFKTKFEPAIKVDVINMADYGLMNGDKVLETALTMME
                     EEV"
     gene            16706..17041
                     /locus_tag="TV193_000857"
     CDS             16706..17041
                     /locus_tag="TV193_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1513074.1"
                     /translation="MTQSSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEKAQHLLQ
                     EATHSLNVAHRSQTNLLSQEAAGDQVDLSLLLVHGQDHMMTALAFIDLAKELVAVYDK
                     ISRIQRGEL"
     gene            17041..17475
                     /locus_tag="TV193_000858"
     CDS             17041..17475
                     /locus_tag="TV193_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEL1513075.1"
                     /translation="MMITAEGDVSVTQCFKAILSSLQEDYHENTLRRLPPAELKAGLS
                     YIKHYGKSKEHNVRVLITALEAPHLYAACFSSNHGLKTLSYRLEALGEKRTKITYCYD
                     YQPLDVFQKANQLIIGKLFKKSFKRQSQAQLAALIQYAKQLS"
     gene            17550..18929
                     /locus_tag="TV193_000859"
     CDS             17550..18929
                     /locus_tag="TV193_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1513076.1"
                     /translation="MSHFSDKFMEISGKMGSQRHLVAIRDSFISLMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAAAMQPIIDINGYVYFGTIGIMALFFAFAFGYHLALMHKVNP
                     LAGGLISFASFVATLPQSLTISTPLEGASASLLAGLKDMGLSVVTANGARVLETSQWG
                     AIALKYAGATGLFTALIIGFLSSFVYATLTKRNLTIKLPDNVPPAVNKAFAAIIPGTV
                     AIYVSAIVAYLIFALTGSSLSDMISTYIQLPLLGLSQGLGSVILLTFLVQLLWFFGLH
                     GHNVLAPVLDGVYLVALTENTAAYNTSQSVANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFAIPWLIVPPICASIA
                     YAATAIGLIPPVFLPVPWITPVGLYAYLATGGSVMAGLVSLFNLFVAFLIWAPFVMSA
                     NKEKASDLS"
     gene            18926..19078
                     /locus_tag="TV193_000860"
     CDS             18926..19078
                     /locus_tag="TV193_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513077.1"
                     /translation="MTAKNGASFLMAIGFFLIAISPMVGNKYLHIVTGLAFVGLGYYL
                     TKRKRP"
     gene            complement(19235..19975)
                     /locus_tag="TV193_000861"
     CDS             complement(19235..19975)
                     /locus_tag="TV193_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1513078.1"
                     /translation="MAELKIDVQDLHKSYGQNEVLKGINAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLESITSGKVVVDGFELSDPNTNIDKARENIGMVFQHFNLFPHMTVLDNI
                     TFAPVELGKVSKEAAKEKGLALLEKVGLADKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(19975..22140)
                     /locus_tag="TV193_000862"
     CDS             complement(19975..22140)
                     /locus_tag="TV193_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1513079.1"
                     /translation="MKNTLKAWMLAMLSVVLMTAGIASAETIDIVSDTAYAPFEFKDS
                     DQVYKGIDVDIINEVAKRKGWNINMTFPGFDAAVNAIQSGQADALMAGTTITAARQKV
                     FHFSDPYYDTKIVIATRKANPIKKYSELKGKTVGVKNGTAAQAFLDKYKKSYGYTVKT
                     FDTGDLMYNSLATGSIDAVMDDEPVIQYAINQKQDLAINMKGEAIGSFGFAVKKGSGY
                     DYLIDDFNEALGAMKADGTYQAIMTKWLGSNDKVTAGKATGDASAKATPLKPVYKIVA
                     DSSFAPFEFQIGSGEYVGIDMDLIKAIAKQQGFTIEISNPGFDAALNAVQAGQADAVI
                     AGMSITPARREIFDFSDSYYTSNIRLGVKSGSSIKSYKDLKGKIVGAKKGTASYDFLE
                     SNKDIYGYRLKAFDEASSMYDSLNSGSIDGLMDDEAILRYAIQRGHKLDIPIKGEPSG
                     EYGFAVKKGANPELIEMFNNGLAALKASGKYDAIISRYLDSEASVKTADESTIYGLLA
                     NNYKQLLAGLGTTLGLTLISFAIALVIGIVFGMMAVSPSKNLRMASTIFVDVVRGIPL
                     MIVAAFIFWGVPNLIESMTGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPAGQ
                     MEASRSLGLSYHTTMRRIILPQAIKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFRMYAILAVIYLIMITLLTRLAKRLEKRLN"
BASE COUNT         6137 a         4309 c         5173 g         6523 t
ORIGIN      
        1 tgatagtgga aattatcact caagaagtac ggggtatcag agcaagactt attttaatct
       61 gagtaagctt cttgtcctta ggctcaagct gatcaggact gagtgaccac ccatttaaac
      121 cggggaacaa ggtagctaac gataatgctg ctaagtccaa taatggttag ccaataaagc
      181 cagctggaat caaagctaag cacgagatga cttccaagga caagcacaac accagaccaa
      241 aacaagatta gattaatcgg gttatcagtg atagtgacct gatcttgatt ggtcacgatt
      301 ttcttggcct gcctgctatg cttgatggtc aaataatcct cagcatcggg gagatcaata
      361 tcgatactct cacccggata aagcttaacc ttgtgggatt tcccgatatt aactgtcata
      421 ggtgctccta tctttgtcaa acgtgtcttg cgccttagct tcattcctaa aatcctctct
      481 aaaataaaag tcaagcataa tcatgccaat tccagccttc aaatgctaca aaagaccagt
      541 gtaccatagc ctatgatacc aaaaagcaga aagaatagcg actgtaaaaa atctgaaaat
      601 aagctttctt acatctattc cctgctttga aagcagactt ttgcaggatc tatgctagaa
      661 tagaaggaaa aggagggcac taatggttaa gggaataata tttgacatgg acggcgtttt
      721 atttgatacg gagccttttt atctcaaacg tcgtgaagcc tttttgacga gtaagggcat
      781 taggattgac cacctcagcc ccgaggattt tattggtggt aatcttcagc agatttggga
      841 caaggtctta gcagggcagg ctaatgctga tgaggcaaga gatattgctg tggcttatga
      901 ggcctataag ctgtgccata agcctcctta ccaagagctg atgtttaaag gggtcaagtc
      961 ctgcctcaaa gctcttaaag ggcagggact taagcttgct ttagcctcaa actctagtcg
     1021 ttgtgatatt ttgttagctt tagagagcag tcatatcaag gcttattttg accttacact
     1081 ggcgcgtgag gacgtcacag ctggtaagcc taatcctgag atttataaca aggttgcgca
     1141 ggctctggga ctggctaaag cagagtttgt cgttgtcgaa gatagtcaaa aagggattgc
     1201 cgcagctaag gctgctggct tgaaggttct agcaatcaaa gacaagcgtt acggcattga
     1261 tcaaggtcag gcagacaagc gcattgatag cctcaggcag ctatgtgagc tgcttaggta
     1321 aggcttctga tagagcagat gtttgttaac tgaaagatag caggctttat agtggcttat
     1381 catcactaca atagaatgat ttgtcttaga atgacagaac ctaaataggt gtttttctcg
     1441 tttttgtagc aggatagctg aagcttttga tctgctttat gtttggtgtt gttattaaga
     1501 gatgaaattg tcagtaatgt tgagcttact gataggaggg ctaatggcag ttaaattatt
     1561 aacagaaaga ttgatcatac aggagttgaa tgagacctat tttgagcctt atcacaaggc
     1621 atttaccgaa gaaatcacag catttcaatg gcctgatccc tttaaggaca tcgctgctgc
     1681 taaggagaca ctagctagct ttatcgcaga aatgaaaaaa ggaaacatgc tagagctagt
     1741 cattttgaat aaagcaaatg acttcgttgg aagcttggaa gtctttagcc ttgatagtga
     1801 gacaccggaa ttgggcatat ggttgaaaaa atcaagtcaa ggactaggct atggctatga
     1861 ggccttgaga gctattgtgg attatttaaa aggcaaaaac aaataccgtt atttcaatta
     1921 tgaggtagat gttagaaata ctggtaatat taagctggta gagaaattca atgtggtgac
     1981 atcgacctat caggaatgtg agacggcttc aaagaaaagg ctttgtttac aggtttatca
     2041 cattcttaat taatcgttgg tatgacatag gtgatagtca tggttttgct ttaagtcctg
     2101 tgtgagttga gagcagcttt cagctctagt atttgcttct ggtgtggtct tttagtccac
     2161 agtctaggta ttataaagaa gagatctggc tttgtttaaa aaacagcttc tctgtctgag
     2221 cttgtaccct caagatatca ttgaagagat agcaggacag ctgttgaaaa tgagggaagt
     2281 aagagggatc tgtgtgccaa gatcaaaagc ataaaaagcc tctagcttac ttcttgtggt
     2341 tagcattttt ttgaaagcat gctaatttgc ctttagtgtg ctttttgttt gctcaagatc
     2401 agctagtcaa tgaggccata gagtaagcct taacaaatgg tgagatgtag ctacagccgg
     2461 ttgtgcagat ggggttagaa taattggatc tactcacagc ctcttgtaat catttcctta
     2521 caaaaatcac actagtaaag acctctaatg gcgaaggagc tcctgacacc aagctctgaa
     2581 gaagctggct atttgtcctt gatcaaaaag ggttaagact gtcagttcaa ctaggtgcaa
     2641 acgactcata aggcaggtct ttagcagggg tgatgtcaaa aaattgacat cagctgtaac
     2701 cttttagcaa aattgtagtc caacaaaagt gagcagacat tttggaaggg ggacctgtta
     2761 ttggaatttg aagacatcta cttgatgtat aaagacgatg tttatccttt tcttcatgcc
     2821 tatgcgtgag acaacttatg acgaggttga accaagggct ttctttatag tataatggtc
     2881 gttaaagtga tattaataag aaagtgatga ctataatgac agaaatacca aaggatttaa
     2941 agctaaatac gattagtgtc tttgagcatt atcatattga tgtgtttgag gctggtcatg
     3001 tgctgttatc aacagagatc catgcgtcag ccttgaacta ttatggaaat gcacatgggg
     3061 gctttttgtt taccctttgt gatcaggttg gtggcttggt ggccaaatca ataggtcttg
     3121 aggctgttac tctgcaagct aatgtgaatt atcttaagcc tggtcatcta ggagaccgtt
     3181 tagtcgtaga aggtagtctg gtgcatagag gtcggaccac acagctgatt gaggtcacca
     3241 tcaaaaatca agatgataga ctattaacca gggttagcct gaccatgttt gtgacaagta
     3301 aaaaacgatc ctctgactag ctgatacaag tcatatcaaa aaacgtccag cttgatttta
     3361 gctggacgtt tggctttagc tgcgatagag cttatggtgc tgataaacag ggtcaaaggt
     3421 cacattgata ccgagctgtc tgagaacatg cttgtcctcg ttggtcagga taacggttga
     3481 atgcgcttcg ctgcccttga gatttcctaa ttctttcatg gctagatcgg cttggttgtt
     3541 gttcattgct gtgatagcca gcgccattag gatttcatta gcgtgtagcc tagggttgtg
     3601 actgcctagg tgattaatct tgagcccttg aatgggcttg acatattctg gctcaatgag
     3661 atgcgtttcc ttactaatgt gggccagtgt tttgatagca ttgatgataa cagcagcggt
     3721 cggaccaaac aaatcagatg ttttaccggt gactacctga ccatttggaa gctgaagggc
     3781 tagggcaggc tgaccagtta tctctgcttt ttgcctagca atgagagtaa cctgtcgatc
     3841 tttgggagtg acaccgatgt cattcatcaa gagctcaagc tttttaactg cagcctcggt
     3901 cacgcgctcc gctttgaagt ctaccaaggt ttgatagtag cggcgaatga tttcttgcct
     3961 tgaggcttcg atagcagcct cctcattaac aatggaaaag ccgaccatat taacacccat
     4021 atctgttgga gatgcatatg gggactggct taaaatacgc tcaaaggttc tgtttagtac
     4081 tggaaagacc tcaatatcac gattgtaatt gactgctgtt ttcccgtaag cctctaaatg
     4141 aaagggatca atcatgttca catcatctaa atcagcagtg gcagcctcat aggctaggtt
     4201 tacagggtgg tggagtggaa gattccaaac agggaaggtt tcaaactttg catagcctga
     4261 tgtgacaccc tttagttggt catgatagag ctgtgagatg caggtcgcta attttccaga
     4321 gccaggacca ggagctgtga cgacaatcag gttacgactg gtcttgatgt agtcatttct
     4381 ccccatacca tcaggagaaa tgatgtggtt aatatctgtt ggatagcctt tgattgggta
     4441 gtggcgataa gacgtaatgc catttttggc taattgcttt tgaaaatgat ccgcagctgc
     4501 ctgatggttg tactgcgtaa ttacaactga gccaacatag atatctaagg cgttaaaggt
     4561 atcaattaaa cggagcactt cctgatcgta ggagattcct aagtcaccac gcgttttaga
     4621 atgttcgata ttattggcat tgatggtgat gacaatctca acctgatcct tgagctcctt
     4681 tagcagcttg attttgttgt caggctcata gccaggcaag acacgcgccg catgaaaatc
     4741 ctcaagtatt tttccgccaa attccatgta gagcttgccg tcaaattgct tgatacgttc
     4801 tagaatatga ttcctttgta agcttaggta tttgttggaa tcaaaagcaa tgtttttcat
     4861 ttatttttca cctctgctaa gcattatagc aaagaaatag tgagaagtga atgatttgtc
     4921 taaaaattag tctcttcctc taagtagcta gggtggcaaa aagcagcgct atttaaatac
     4981 cgataaaaaa tgacttgaca aaggtgactg acttgcttat actaggaaca attaaatacc
     5041 actttaatga tgttctgtga ggcatgaaag tgacaagaca aagaggagtg agcctgctct
     5101 tattttgctg tagactgaat gcgactgatg gactggtgcc taggtctttt ttaatgggct
     5161 taaagggtat tcaattaatt aaggtagtca gtgagctact attaaaagga gaataatcat
     5221 gtcagcattg tctttagaca agaacaacaa gcgtgcgctt tgggctgcta ttgccgcttc
     5281 aggaacagat gatcttaacg ttatgtttct agccttttcg atgtcctcta ttatctctga
     5341 tctaggagtg agtagtactc aaggaggctg gatagctact atcactaatc taggaatgct
     5401 ctttgggggc ctgctctttg gtctgcttgc tgatagacat cataaattta aggtattcaa
     5461 atggacgatc cttatttttt cagtggcaac aggcttgatt tattttacca agacgattga
     5521 atttttatac ctcatgcgct ttattgctgg tattggggtt ggtggtgaat atggtgttgc
     5581 tattgcgatt atggcaggac ttgtccctgc tgaaaaaatg gggcgcgtct catcgctaaa
     5641 tgggattgca ggtcaggttg gatcaattgt ttctgcttta ttagcaggct ggctagcacc
     5701 tgctcttggc tggcgcggcc tctttctctt tggtctggct ccgattttac tagtcatttg
     5761 gatgatggtt gctattgatg atgataagat tattgataac catgtcaatg tttcagagga
     5821 agctagtcag ccggtaaaga ttagtgagtt atttaagaca ccagccttga caggacaaac
     5881 tctcgctttg atggtgatga cgacagttca gattgctggt tattttggta tgatgaactg
     5941 gctgccaact attatccaag ctagtctaca tatttctgtc aaggattcgt ctctgtggat
     6001 ggtatcaacc attgtgggca tgtgccttgg aatgctgacc tttggccatc tgctagatac
     6061 ctttgggcca agattggttt attctatctt tttgcttttg tcctctgttt gtgtctatct
     6121 ttttcagttt gccaattcga tgtcaaccat gcttattgga ggagctattg ttggattttt
     6181 cgttaatggc atgtttgcgg gctatggtgc gatgatcaca cgactctatc ctcatcacat
     6241 tcgatcaaca gctaataacc ttatcctcaa tgttggacga gctgttggag gcttttcatc
     6301 ggttatcatc ggtaaaattc ttgatgtttc aagtgtctct atggtcatgc tctttttagc
     6361 cctgctgtac cttgttagct ttgtggcttt gtggacaatc aaaaatctaa aggcagagcg
     6421 atatcaagcg ctgacaaaat agatctggta agtgtagtag gattagtagc aaaggttttg
     6481 ttaaagctct caaaaagcgc ttaggcattt agactaagcg ctttttgacc tttaaagctt
     6541 ttccaaaaag gcgtcttggt caaccctgac acgtgtgtgg caggctctgc caatgagctt
     6601 atggttggca aaggcttcga tacgaaagtc gtattttctg ccctcttcct tgagtgcagt
     6661 gataacaatg gttactgcct gaccgatttt agaggcagct aggtgctgga tagcgatttc
     6721 acttccaacg gttgtttgct tgtcctttag ctgactttgc agaaacgtga aggcagcatg
     6781 ctccataaag gcgacaagag caggtgttgc taggacctct aagccaccag agcccattgc
     6841 ttgagcagaa tgcttgcttt ttgtttcgta tagctgtgaa taaatagaca tgataccctc
     6901 cttttttatt attataatat attaagggct tacagtctta aatgagctgc cttttgtgct
     6961 atactaagaa ttagcttgaa agagctgttg ctgaattaat gtgtctcgca tgggccagac
     7021 taagcatcag ctaacagtaa gaagaagggg aatacatgcg cttagataag tttttagttg
     7081 atgctggctt aggcagtcgc agtcaagtga agctgctatt aaagaaaaag caagtcagtg
     7141 tgaatggggt tagccaaacg tctccaaaat atcaagtcaa tgaaatgacc gatgaggtta
     7201 gctatcaggg acaaaggctc aattatgagg cctttgtgta ttatatgctt aataagccta
     7261 aaggagtgat ttctgcgact gaggattcta gccataagac agtgctggat ttgttagatg
     7321 atactgcacg tcaaaaggct gtctttcctg ttgggcggct tgataaggat acgcatggct
     7381 tgctcttagt gaccaatgat ggaaagctag cacatgctct tttgtctcct aaaaagcatg
     7441 ttgccaagca ataccttgct gtggtagacg gtatgatgac tcaagaggac gtcaagcatt
     7501 tcgcacaggg aatcacttta aaggatcacc aatgcatgcc agcacatttg gacattcttg
     7561 agattaacga atcgctaaaa accagccttg tcaaaatcac catcgaggaa ggaaaatttc
     7621 atcaggttaa gcgaatggta gcagcctgtg gtaaaacagt cagcgattta cagcgcatta
     7681 gtatggggcc cttacagctt gatagtgctt tggcgcctgg agcctatcgt aggttaacag
     7741 cagcagagct agaggctggc tgggttagct gctgaattga tagtaaaaaa gaccagtctt
     7801 agactgatct gtagggtgat tagatcgccc attctcctcc tcggaagatt ggaatgactt
     7861 ctccgtcttt ggtaatgcca tcgatatcca tttgttcaga accaatcata aagtccgcgt
     7921 gggctgttga gcgatttagg ccagccgctt cccaaatgtg ctgctcaggc attccaagtc
     7981 ttaggtcagt tcctggtgcc ctgtagtgaa ggctgtcaaa ctgataatca ttgaggagcc
     8041 ttgccttttt ttctaaacgt tcctgatgtt ggtcccaggc cttgacagga tctgtctcgt
     8101 aaatgcgatt cattttgaaa atggcatccc acaaagcgtc cacctgctct tcttcgcttg
     8161 tcaggtttgg aaaaaccata gcagcccatt cgggaccggc tgcagctgct agattccagc
     8221 tgactttgtt ggcctgagtg gcagcccgct gtttttcaag agcaatagct gttgcgcgtg
     8281 ttgctccagc tagcctatca gaatcaatat cagcaaagac gtttggattg gcagagcgaa
     8341 tgactaagcg gcttgctttt tgatcaagga gataatgtga ctgttcaacg acataatctg
     8401 gtacctgcaa gagacggtct tcatcagcct taagaagctt ctcgcgtgtg atctgatcgt
     8461 cattatagtc aacaagaacc tcagctgcac cagcctcata ggcttttttg gttaatagcc
     8521 gcgcaagctt gtgttgctct actgcaatag aaatgagtag tgtgtgacct ttttgaatgt
     8581 tgactccttt tttgataaga aggttagcgt atttttcaag ataatcgtca aaatgtggca
     8641 aaaccatagc agtctcctaa tatgttaatg ttgcaaaatt taatgtatca tatttgcgac
     8701 tatttcacaa ggagctagcc tgtttcatag gctaaatgtc tcctagaatg cctatcgtaa
     8761 aaggctcagt gttggttttc tctgatgagt taaaaaacga tccctttttt gatcagtttg
     8821 cgctgccctt gctaatagat atttgcttaa tagcgacatt cgtgttaaga tataagagga
     8881 aaaaatcaat agatgaggta tttaacagtg gcatttggag aaaatggacc tcgcaaaaaa
     8941 actgcctttg aaaagttgac aacagttgtt gtgatcgtga tggttcttgt gactgtcggt
     9001 ggacttattg cgggtgccct gtcagtattg atgtaagaaa acgctgaaag gcgttttttt
     9061 aggataagag aaggtttgag aagaaaagta tgagtatgtt tttagatact gctaaggtca
     9121 gtgttcaggc tggtcgtggc ggtgatggta tggtggcctt tcgtcgtgaa aaatatgtgc
     9181 ctaatggcgg cccttggggc ggtgatggtg gcaagggtgg ctctgtcatt ttcaaggttg
     9241 atgaaggttt gcgtacccta atagactttc gctacaatcg taagttcaag gccaaatccg
     9301 gtgaaaaagg catgactaag ggcatgcatg gtcgtggctc agaggatttg attatctcag
     9361 tgccacaggg aacgactgtg cgtgatgctg aaaccggtaa ggttctgacg gatctggttg
     9421 agcatggtca agaatttgtc gtggctaagg gtggtcgtgg cggtcgtggg aacattcgtt
     9481 ttgcaacgcc gcgcaatcca gcacctgaga ttgctgaaaa tggtgaacca ggagaggagc
     9541 gccaattaga gctagagctt aagattttgg cagatgtggg actggttggt tttccgtcag
     9601 ttggtaaatc aacgctacta agcgtggtct catcagccaa gcccaagatt ggtgcttatc
     9661 actttaccac tattgtgcct aatctaggta tggttcgaac caaatctggt gagagctttg
     9721 ctatggcaga tcttccaggc ttaatcaagg gagctagcca gggtgtgggg cttggcactc
     9781 agtttttgcg ccatattgag cgtacacgtg tgattctaca tgttattgat atgtcagcag
     9841 ctgaaggacg agacccttat gaggactatg tggcgattaa taaggagtta gaagcatata
     9901 atcttcgtct tatggagcgt ccgcaaatta tcgtcgccaa taaaatggat atgccagagg
     9961 caaaggagca gttgcagcgc ttcaaggaac agttagctgc tcagtatgat gactttgaag
    10021 aactgccaat aattttcccg atttctagct tggcacatca aggcttggat agcctattag
    10081 aagcaacagc agagctatta gcaaaaactg atgatttctt gttgtatgat gaggctgatt
    10141 tggctgagga cgaggcttat tatggctttg cggctgagga aaaggccttt gagattagtc
    10201 gtgctgatga tgcagcttgg gtattgtctg gtgagaaatt agagcgtctc tttgtgatga
    10261 ccaatctgga gcgcgacgaa tctatcatga aatttgctcg tcagctacgt ggcatgggtg
    10321 ttgatgaagc gcttcgtgag cgtggtgcta aggacggcga cattgttcgc attggcaagt
    10381 ttgagtttga atttgtagac taatgacaaa taccaagctt agctgttttt tgtagcaagt
    10441 gatgctgagt catatctgaa gtaggctgtt tgctcaattc acagcaatga ggtcttggtt
    10501 gatgtgagct agggaggttt tttatgggag ataaaccaat atccttcaag gataaggacg
    10561 gtaactttgt ttcggcagca gatgtctgga atgctgaaaa attagaagaa ttatttaatc
    10621 tcttaaatcc caataggcgt ttgcgtttgg aacgtgacaa attaaaaaag gatgaagctt
    10681 aagtgcactt cctctcaatc gttagattta gtgtctaact tttgagggtg cacttcaagg
    10741 cttcgtcctt ttttgatgct ttttttcttg gtgatgctgc aaatgtagcc aattaaaaaa
    10801 ggtgtaaatg tcattaacaa gaaaggctgc aaaacaaatg accactgcgt attggctggt
    10861 atttgcttga gcagcataga gccacaggag aattaagacc aaatcattaa gagcataggc
    10921 caaggcaaaa taagggctac gtttgtagct taagtaggct gctgaaaaag aggtggcaat
    10981 agataaggta gaaacaggca gataggctgt cttaagatag gctaagatag catagaacaa
    11041 gctggtaact agtatggtaa gaaccactaa gcgcagccgg tctgctgttg tcaagcgtga
    11101 gatggttacc tgagatgtct ggtcttcaaa tgggtggctt agccaggtaa acagtgacaa
    11161 aatagccatc ggcagggtca tgaagagata ggttatcagc tccccgtaat aactgtttaa
    11221 tagtgacaga taggcataaa taagggagaa aataatggcc aagctctgtc caatcggatt
    11281 tgccttggca ctaaagatta aagctgtcac accgattaag gaagctatca gtgctaaggg
    11341 agcttgttct ccaaagaaaa aggcactgag gagaatagcc gaaatggagg ttaaccaaag
    11401 cgtccactcg gtttttgtaa aatagtttaa ataagccata tccttattca agcataggcc
    11461 tttttatctg tcaatagggt gtcgacctta gggaaaaata agctaatacc tgccatagtg
    11521 caattggttg tgaggcacta atactagcag ataatggtgt taactagagg caaatgagct
    11581 aagagtttcc ttattggctg ctgctaatac tccttgttga ctggtttaga agaaaaggac
    11641 taagagcctt agcttggctt tgtcagttag tttccttgat gataaggaaa aactagattt
    11701 tttaaagcgt ttacagtgtc cttttttctt cctataatag gggtataagt gacaaaaaga
    11761 aaggaaaaag catatgaagc aatcaaaacg ccgttaccaa tttccagaag gttttttgtg
    11821 gggaagctca acatctggcc ctcaaagtga ggggactgtt tctggagatg ggaagggacc
    11881 tagcaattgg gactactggt ttagtctgga gccagataag tttcatcatc agattggtcc
    11941 agaggtaacc tcaacctttt acaccaacta caaaagcgat attgctcttt taaaagagac
    12001 cggtcacaca gcttttcgga cctctattca atggtctcga ctgattccag aaggggttgg
    12061 tcaggttaat ccaaaagctg tagcctttta ccgagaggta tttcaggaaa tcatggctca
    12121 ggacattaag ctgattgtta acctctatca ttttgatctg ccttatgcct tgcaaggaaa
    12181 gagaggctgg gaggctaagg agacggtctg ggcttatgag acctatgcta agacctgttt
    12241 tgagcttttt ggtgatttgg tggatacatg gattaccttt aacgaaccta ttgttccagt
    12301 cgaatgcggt tatttggggc attaccacta tccttgcaag gtagatgcca aggcagctgt
    12361 tcaagtggct taccataccc agttggctag ctcacttgct atcaaggcct gccacgagtt
    12421 gtatcctaag cataggatta gtattgtgct taatgtgact cctgcctatc ctagaagtga
    12481 tcagccagaa gatgtcaagg cagcgagaat cgcagagctt ttccagacta aatccttcct
    12541 agatccgtct gtcttaggag tgtacccaga agagttagta gttcttttag aggcagctga
    12601 tttattgccc cagtatagtg ctgatgaatt ggctattatc aaaaacaatc ctgttgattt
    12661 cttgggagtt aattactatc aacctttgcg tgtgcaagcg cctagcaaaa caagacaaga
    12721 tggtgaacca atcacgctag cctcttattt tgaaccttat gatatgccag gcaaaaaggt
    12781 taaccctcat cgcggttggg aaatctatga gcagggcctt tacgacattg ctcttaattt
    12841 aaaagagcat tatggcaata ttgactggtt agtaactgaa aatggtatgg gagtagaagg
    12901 tgaagaagcc tttttagttg atggtcagat ccaagacgat taccggattg cctttatcga
    12961 agaccatttg attcaattgc acagggcttt agaagaaggc gcgaactgta aaggctacct
    13021 cctgtggacc tttattgatt gctggtcttg gttaaatgcc tataaaaatc gttatggctt
    13081 ggtagccttg gatttagaga ctcaaaaacg aacccttaaa aaatctggcc actggtttaa
    13141 gaccctgagt cagacaaatg gttttgataa ataggagcgt atgatggtca ccttaggatt
    13201 ttccctttac cctgagcggc atggttttgc taagagtaag gcttatattg atttactgca
    13261 ctgctatgga gccaagcgct tgtttatgag cctcttacag ttggcgccaa atgatcccaa
    13321 gacctttaag ttttatgcgg atctgattgc ttatgccaat tgcttgggca ttcgggtcat
    13381 tgcagacgtt agccctgctt ttatcaagca ggctggttgg tcagatcagg ttattgaaga
    13441 ggctcatgct tttggcttag caggcttgcg tttagatgag gccttgcctt tagaggatat
    13501 tgttaggcta acgaaaaact cttttgggct taagattgaa ctcaatatga gtactgacaa
    13561 gagtttattg acagccttgc taaaggcagc tcctgatcgg agtaacctca ttggttgtca
    13621 taatttttac ccgcacgcct ttaccggcct gtcactggag cattttaagg aaatgtccca
    13681 tttttaccac gagcatggga ttgcaacggc tgcttttatc acagcccaat cagcaaagga
    13741 aggcccttgg ccgctgtcag agggcttacc gactgttgag gctcatcggc aattgccaat
    13801 tgacgtgcag gtggaactga tgaaggcgac aggaactatt gatactgtca ttttgtccaa
    13861 tcaattcatc actgaagatg aactcgttca gtgccgtcaa gccttggata gatcagtcat
    13921 gtctattaag gtcaagcctc tggttgattt gacggacata gaggagaaga ttatctgtta
    13981 cccacattgt tatcggggag atgtatcaga ttatgtgatt cgctcaacca tgccgcgtgt
    14041 ggtatatgct caagaagcaa ttgctccaag agagcagccc aagcaggtta agcgaggcag
    14101 tattatcatt gataatgacc gttacaacag gtacaaggga gaattgcaaa ttgcactcaa
    14161 agcctttacc cttagctcaa aggccaatgt ggtcgccaac attaaagagg attacctaag
    14221 cctattagac gagttgaagc cctggcagga gttttcattg gtgattgaga ctgactagtc
    14281 tggcttcaca atcgatacgg aaaatgatgg tcactttttt caggaaacat ttgctaaact
    14341 aagagagtaa agaaagcgtt ttctaaaaga cgaaggagga atgatgctat caaaaaaaga
    14401 aatggctata gtagcatttc taatcagcca aaaagggcag tttgtctcta gtgctacctt
    14461 ggctaaggct attggcatga gtgatcgcac agtcagaaaa tacctaaagg agctgattag
    14521 cagccttcct agtaagggag cgcacatcat ttccaagcaa ggtcagggct actgtttaga
    14581 gattgatcat tctatggcgt ttgagatctt ttggcaggaa agcttggcct ctaaaaagcg
    14641 cttggctgat gtgactcagg tggaagaaac agttgatcgg gagcattatt tgctaaataa
    14701 attcttcttt gaagagcccg tttgggattt tgaagagctc tgccaagaat tgtatattag
    14761 tcggacgacc ctaaaccatg ttttagcggt tattagagac cgtattaggc cttatcagct
    14821 acagcttgat gtgagtcatc agcgcgttca ggtgacaggt aaggaagagg ctattaggca
    14881 ttttatcatg gattattttt ttgctaccag ctttgatgac tccatgtacg ccatagtaga
    14941 caataccttt cttgatcata tcaagtttgc tgatatcaca ataattgttt tagatgaatg
    15001 tcgagatgcc aaactaaagc tttctgattt tgtcatgcac aatttggttt tgcacattgc
    15061 cctaatggtt cagcgtattc ggtctggcta tccgttagca tttttttcca ttccagcagc
    15121 tattcgccaa tcagacgagt atcaagtggc tctacgtatt ttatatcgag tagaagaagt
    15181 gatgggcatt cgttttccta aagaagaagc taactatatt gctttacacc tcaaggttaa
    15241 gcattccgtt gatggcagcc cacaggacaa taaggccgat gacttgctga gaagtcattt
    15301 aaaagcaggt attgtcaagg ctagtcagct gacaggtatg tctttggagg ctgatagcag
    15361 cttgcttcaa ggcctattgg cccatatgaa gcctttagcc acaaggcttg aaaatcatat
    15421 tcagctgacc aatcccttaa ctgaggagat taaaagcaaa tacccagagg cttttgccct
    15481 gactaagcaa gcttttgaga atattcctga gcttcaggct tatgacctgt ctgatgacga
    15541 atgggcttac attagcttgc atatcatggc agctattgag cgctattcca atcgtcacaa
    15601 actgagggtg cttgtggttt gtgccacagg ctatggcagt gccatgatgc tgaaaaatcg
    15661 cttggaaaag gaatttgaag gtcgctttca gattgtagat gttatcagct actatgaaat
    15721 aacacaggaa cgactgcaaa cggttgatgt gattatttct tctatcagcc ttgctaatgt
    15781 catgttttta acgccagtca ttactgtcag tgtcttttta tctgatcaag acatcaaagc
    15841 cattcgccaa tttatcgggg agcaggaggg aataagaaga gaagctgcgt cgtcatcgca
    15901 gatgagcttg gaaaaagcag agcagattct aaaaggtgtc tttagtccta agcgttttct
    15961 ttatgtgaaa gaaaaactat caaagaaggc cttgctgtta aagatgattg cttgtcttga
    16021 cgaagcaatg gatgaagcct ttgttgaggc cttttatcac caaatcgtgt tgagggaaaa
    16081 ttatagctca attgtttttg gtgaggtgct tgcctttcca cacccggcta atcccatgac
    16141 ctattctgaa caggtggtgg tggctgtctg tcaagagcct attgactggg acgagagtca
    16201 tcgggctgtt cactttatct ttttgttgtc accgtccaag ggacgtaaca gctatttaaa
    16261 atatatctca ccgagcttgg tgtcttttgt caatcaagca gagcttcagc aggctttatt
    16321 agaagaacca agctatgcac aattcatcac attatttacc ccactcatca ctgaataaaa
    16381 ggagaagtat tatgaaaacc attatgttag tttgtaatgc cggcatgtca accagtatgc
    16441 tggtgactaa aatgcaaaaa gccgctcaag cgcgtggcat cgaggttgag atttgggcag
    16501 ttcctgtgag cgaagctgac aatgaggttg ctgctaaaac cattgatgtc ctcatgttag
    16561 ggccgcaggt caaattctta ctaaaggact ttaagaccaa atttgaaccg gcaattaagg
    16621 tagatgtcat taacatggct gactatggcc tcatgaatgg tgacaaggtg cttgaaacag
    16681 ccctaacaat gatggaggaa gaggtatgac acaatcatca aacctagagg ccattatggg
    16741 attaatcatg tatggcggtg aggccaaggg caaggctgta gaagctattc atgcagctag
    16801 agatggtcaa tttgaaaagg ctcagcactt gcttcaagag gctacacatt ctttaaatgt
    16861 tgcccataga tcacaaacca atttgctatc tcaggaagca gctggagatc aggttgattt
    16921 gtctttattg ctggtgcatg gtcaggatca tatgatgaca gccttagcct ttattgattt
    16981 ggccaaggaa ttggtcgctg tttatgacaa aatatcaaga atccaaagag gtgagctatg
    17041 atgatgatta cagcagaagg agatgtctct gtcactcaat gcttcaaggc tatactaagc
    17101 tctctccaag aggattatca tgaaaacacc ctgagacggc tgccaccagc tgaattaaaa
    17161 gcagggctaa gctacataaa gcattatggc aaaagcaagg agcataacgt tagagtgctg
    17221 atcacagcct tagaagctcc gcacttatat gctgcttgct ttagctctaa tcatgggcta
    17281 aaaacattaa gctaccgctt agaagctctg ggagagaagc gtaccaaaat aacctattgc
    17341 tacgactatc agccacttga tgtctttcaa aaagccaatc agctgatcat tgggaagctt
    17401 tttaagaaga gcttcaaacg gcaatcacaa gcccaattgg cagcccttat ccaatatgct
    17461 aagcagctaa gctaggggaa gatttgagta cagattatct ggctgattat agggcttatc
    17521 atactaaaaa atagaaacag gagaaaatta tgtcacattt ttcggataag tttatggaga
    17581 tttcaggaaa gatgggatcc cagcggcatt tggttgccat tcgtgattcc tttatttcgc
    17641 taatgcccat cacgatggcg ggctctgttg ccgtcttgct gaatgttttc ttgcgtgata
    17701 ttccaaacaa tatgggctgg actggttttg cagcagccat gcagcccatt attgacatca
    17761 atggttatgt gtattttggg acaattggta tcatggcact cttttttgcc tttgcttttg
    17821 ggtatcattt agctcttatg cacaaggtga atcctttggc tggaggttta atctcctttg
    17881 cttcctttgt cgccaccctt cctcaaagct taaccatttc cacaccactt gaaggggcgt
    17941 cagcaagttt attagcaggc ttaaaggata tgggactatc agtggtcact gcaaatggag
    18001 cccgagtttt agaaacaagc cagtggggag caattgccct caaatatgct ggagcaacag
    18061 gtctttttac agcattgatc attggctttt tatctagctt tgtttatgcg actttgacca
    18121 aacgtaacct gaccatcaaa ttgccagata atgtgccacc tgcggttaat aaggcttttg
    18181 cggctattat tccagggaca gtcgcgattt atgtgtcagc gatcgtagct taccttattt
    18241 ttgccctcac aggctcgtct ctaagtgata tgatttcgac ctatatccaa ttgcctttgt
    18301 tggggctgtc tcaagggctt ggctctgtta tcctgttaac cttcttggtt caattgctct
    18361 ggttctttgg tttgcatggt cacaatgtct tagcacccgt gcttgatggt gtgtacttag
    18421 tggctctaac agaaaataca gctgcctata ataccagtca gagcgttgct aatctgcctt
    18481 atctctggac gagaggctcc tttgatgcct atgcacaaat gggtggttca ggtgttactc
    18541 tggctctgat tattgctatc tttattttct caaaacgtga ggagcacaag accattgcca
    18601 aattatcagc accgatgggc gtgtttaaca tcaatgagcc aattaccttt ggtatgccta
    18661 ttgtcttgaa cccaaccttt gctatcccat ggctaatcgt accaccaatt tgtgctagca
    18721 ttgcttatgc tgccacagca ataggcttga tccctcccgt tttcttgcca gttccttgga
    18781 ttacgccagt tggactttac gcttacttgg ctactggagg tagtgttatg gcaggtctgg
    18841 tttccttgtt taacctcttt gttgcctttc ttatctgggc accatttgtc atgtcagcta
    18901 ataaagaaaa agcgagtgac ctttcatgac agcaaaaaac ggagcaagct ttttaatggc
    18961 tataggattt ttccttattg ccattagtcc aatggttggc aacaaatacc tacatatcgt
    19021 gacaggacta gcttttgttg gcttagggta ttatctcact aagcgcaagc gtccttagtc
    19081 aatgcgagca gctagcccct atgaaaagac aaacctaagg gctagccttg attttctatc
    19141 ttggttatcg catttaaaag caagcaaaaa agcaagggta gatgcttacc tttgcttttt
    19201 ttattttttg acctttaata gaatatcttg ctacttaaac atttaagacc ttatctaaaa
    19261 attcaattaa gcgtgggtgc ttagggtgat caaagatttc ctctggagta ccgtcctcta
    19321 ggaattggcc gccgtctgta aagatcacac gattagccac ttgacgagca aagcccattt
    19381 catgtgtcac aatcagcatg gtcatgccct gctctgctag gtctttcata acgtttaaga
    19441 cgtctccaac catctcaggg tcaagagcag aggtaggctc atcaaagagc atgatatcag
    19501 ggttcatggc aagacttctt gcaattgcaa cacgctgctt ttgaccacct gatagacttc
    19561 ctgggaaagc gtcagcctta tcagctagac cgaccttctc tagaagagca agtccctttt
    19621 ccttagccgc ctcctttgag acctttccaa gctcaactgg tgcaaaggta atgttatcaa
    19681 ggactgtcat atgtggaaag agattgaagt gctgaaacac catgccgata ttttcacgag
    19741 ccttatcaat attggtatta ggatctgaaa gttcaaagcc atcaaccaca accttaccac
    19801 tagtaatgga ttcaaggaga ttgagggtgc gcaggaaggt tgattttcca gagccagatg
    19861 gcccgataat acaaacgaca tcaccctcgt aaaatttagc attaatgcct tttaagacct
    19921 cattttgccc ataggatttg tgtaaatctt gaacatcaat ttttaattct gccattagtt
    19981 aagcctcttt tctaaacgtt ttgcaagcct tgttaagagt gtaatcataa tcaagtagat
    20041 aactgctagg atagcataca tgcggaagga ttgatagttt ctagcgataa tgattttccc
    20101 tgtttggaag agctccacta aaccgatcgc tgagactatg gtcgtatcct tcaaggaaat
    20161 gacaaactga ttgatgaagt ttggcagcat tagcttaatg gcctgaggaa ggataatcct
    20221 tcgcattgtt gtgtgatatg acaagcccaa gctgcgacta gcctccattt gacctgccgg
    20281 cacagcctcg atacccccac gaacaatttc ggcaatatag gctccaccat ttagcgaaag
    20341 tgcaatagta gcagctacaa aatcgttaat cggtgattga tgcccagtca tgctttcaat
    20401 gaggtttggc actccccaga agataaaggc agcaacaatc atcaagggga taccacgcac
    20461 cacatcaaca aagatagtag aagccatgcg caggttcttt gatggggata cagccatcat
    20521 tccaaaaaca ataccaataa ccaaagcaat ggcaaaggag atgagtgtca gaccaagggt
    20581 tgttccaagc ccagccaata attgcttgta gttattagct aaaagtccat aaatagttga
    20641 ctcatcggct gttttgacag atgcctctga atcaaggtat ctgctgatga tggcgtcgta
    20701 ttttcctgat gctttaagag cagccaaacc gttgttaaac atttcgatga gctcagggtt
    20761 ggctcctttt ttaacagcaa aaccatactc accagaaggc tctcccttga taggaatatc
    20821 aagcttgtgg cctcgctgaa tagcgtacct taaaatagct tcatcatcca taagcccgtc
    20881 aatagaacca gaatttaagc tatcgtacat tgaggaggcc tcatcaaagg cttttagacg
    20941 gtaaccataa atatccttgt tgctttcaag gaaatcatag gaggctgttc cttttttggc
    21001 accgactatt ttacccttga ggtccttgta tgatttgata gagcttccgg atttgacccc
    21061 aaggcgaatg tttgatgtgt agtaggaatc tgaaaaatca aaaatctcac gacgtgcagg
    21121 tgtgatagac atacctgcaa taacagcgtc agcctgacca gcttgaacag catttaaagc
    21181 agcgtcaaag ccaggattgc tgatctcaat ggtaaagcct tgctgcttag caattgcctt
    21241 gatgaggtcc atatcaatac cgacatattc tccgctgcca atttgaaatt caaagggagc
    21301 aaaggaggag tcagccacga ttttataaac cggctttaaa ggagtggcct tagcagaggc
    21361 atcgccagta gccttgcctg ctgtgacctt gtcattgctg ccaagccatt ttgtcatgat
    21421 agcttgatag gttccatcag ccttcatagc gcctaaggct tcattgaagt cgtcaatgag
    21481 ataatcatag ccgctgcctt ttttgacagc aaagccaaag cttccaatag cctctccctt
    21541 catgttgatc gcaagatcct gcttttggtt aatggcatat tgaatgacag gctcgtcgtc
    21601 cataacagcg tcaatagagc ctgttgcaag actgttgtac atcaggtcac ctgtgtcaaa
    21661 tgttttaaca gtataaccat acgatttttt gtatttatct aagaaggctt gagcagctgt
    21721 tccattttta acaccgactg tttttccttt tagctcgcta tatttcttaa tagggttagc
    21781 ctttcttgta gcaataacaa tttttgtatc gtaataggga tctgaaaaat ggaagacctt
    21841 ttgacgagca gcagtgatgg tggtgcctgc cataagggcg tcagcttgac cagactgaat
    21901 ggcattgaca gcagcatcaa agccagggaa tgtcatattg atattccaac cctttcgctt
    21961 tgctacttca ttgatgatgt caacatcaat ccccttatac acctgatctg aatccttgaa
    22021 ttcaaacggt gcataagcag tatcagaaac aatatcaatt gtctctgcac ttgcaatccc
    22081 agcagtcatc aaaacaactg acagcattgc aagcatccat gcttttaatg tgtttttcat
    22141 ac
//
LOCUS       DARYXS010000028        21444 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.028, whole genome shotgun sequence.
ACCESSION   DARYXS010000028 DARYXS010000000
VERSION     DARYXS010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21444
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.028"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            132..905
                     /locus_tag="TV193_000863"
     CDS             132..905
                     /locus_tag="TV193_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEL1513080.1"
                     /translation="MIEIFDTHTHLNVDHFSGKEEEELALAKEFGVSYHNVVGFDQET
                     IDQALTLADAYREVYATIGWHPTEAGSYTQAVEDSLIACLKHPKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARHLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRID"
     gene            877..1473
                     /gene="rnmV"
                     /locus_tag="TV193_000864"
     CDS             877..1473
                     /gene="rnmV"
                     /locus_tag="TV193_000864"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEL1513081.1"
                     /translation="MQRGCLELTEKLKIQEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYHGERIRKLIMRAVPTARHAFLRRHEAKPRSKS
                     KGRSLGVEHASFEDLQKALSQVTQSFDDESYFDISQTDLIRLGLLLAADSRKRREYLG
                     EVLRIGYSNGKQLLKRLKLFGITLSEVEDVMTSYQTEQ"
     gene            1817..2689
                     /gene="rsmA"
                     /locus_tag="TV193_000865"
     CDS             1817..2689
                     /gene="rsmA"
                     /locus_tag="TV193_000865"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEL1513082.1"
                     /translation="MRIADYSVTKSILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKPSIRGEALSIQ
                     DFGRLADALKQVGF"
     gene            2850..3722
                     /gene="rsgA"
                     /locus_tag="TV193_000866"
     CDS             2850..3722
                     /gene="rsgA"
                     /locus_tag="TV193_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEL1513083.1"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNTNLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIAPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRRLSHSCKFRSCTHTHEPKCAVKEALGNGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            3731..4393
                     /locus_tag="TV193_000867"
     CDS             3731..4393
                     /locus_tag="TV193_000867"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEL1513084.1"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMKAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPECLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAADLAAQVQTLRAAL
                     NG"
     gene            4386..5018
                     /locus_tag="TV193_000868"
     CDS             4386..5018
                     /locus_tag="TV193_000868"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEL1513085.1"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDA
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIKVHVPKGYLIIIQSKDRS"
     gene            5020..6291
                     /locus_tag="TV193_000869"
     CDS             5020..6291
                     /locus_tag="TV193_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEL1513086.1"
                     /translation="MDLILFVLVLVLIGLAAYSFVSIKHLQSRLEKALDDNADNLSDQ
                     LTYQLDMANKSQLLELSTVMNRQQNELFQQLMVIRDTLHQGLAENRDRSDQRLETMTQ
                     SLSQAVKNLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMR
                     TVAKDVGTLNKVLSNTKTRGILGELQLGQIVEDIMTANQYEREFATVSGSSDRVEYAI
                     KLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYEAGDRAAIETSRKALLAAIKRFAKSIH
                     SKYLNPPETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAI
                     VRALATVEGYQDQSTQSLLHIPLLEEADDED"
     gene            6281..7219
                     /locus_tag="TV193_000870"
     CDS             6281..7219
                     /locus_tag="TV193_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEL1513087.1"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMKGRREVYNGTPQVNQITLRNIRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRIGEGEMTNRIFAMDNRSFYKPKY"
     gene            7319..8134
                     /gene="purR"
                     /locus_tag="TV193_000871"
     CDS             7319..8134
                     /gene="purR"
                     /locus_tag="TV193_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEL1513088.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGY
                     IYLSDLLSTPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVR
                     RDLKITEGSTVSVNYASASSYRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSL
                     LTEFDSTLVGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            8171..10675
                     /locus_tag="TV193_000872"
     CDS             8171..10675
                     /locus_tag="TV193_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEL1513089.1"
                     /translation="MEQENSRTKHVKSTIALTSTIALLGTSVGVSHQVKADDAKSGDA
                     NTSNTSEATLAKPETLEEAVLAVKATEETLSERKKELAETNTNIAETEGEIANLEATK
                     KEQIAELAKAEELLETYSSMSEEDLAKSIEKHETELETINTELEKATTESQAQAEAVA
                     KQQETIAAEATKADQLATQLTAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKATANLATVKETVHSQLTSDLAANKAALAAKEAELQRLQNGVATAQLNVAGSNKLIL
                     PKDYPIEEIKKLAASGYIGTAAYNQYYQAVKDTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLSQEVQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKETHQNTR
                     PSFVYGQVDASGHRGVGPHDQTIIEESAVKVGLRQKDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAVNFLRVDKTDPNAPVYLGFSTSNVESLNEHFVIFP
                     ESDIVDATRFSTTEIPKSGQVIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISQLQHQLEAAQAKSHKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKANLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQASLSDLQAQRARLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPTSHSYGAGAAS
                     HAAVDDNTQRAVQAGMVMLAAAGLATVKLKKGSKKR"
     gene            10858..11271
                     /gene="rpsL"
                     /locus_tag="TV193_000873"
     CDS             10858..11271
                     /gene="rpsL"
                     /locus_tag="TV193_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEL1513090.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            11292..11762
                     /gene="rpsG"
                     /locus_tag="TV193_000874"
     CDS             11292..11762
                     /gene="rpsG"
                     /locus_tag="TV193_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEL1513091.1"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            12305..14383
                     /gene="fusA"
                     /locus_tag="TV193_000875"
     CDS             12305..14383
                     /gene="fusA"
                     /locus_tag="TV193_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEL1513092.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            14400..14618
                     /locus_tag="TV193_000876"
     CDS             14400..14618
                     /locus_tag="TV193_000876"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513093.1"
                     /translation="MDSIPAFLMCYNRWAVQQLIKAMTEKSSPIRHKRLGKGLKKALL
                     TTLSDTFGCPKKLFAVSILMEKQSFENG"
     gene            14764..15774
                     /gene="gap"
                     /locus_tag="TV193_000877"
     CDS             14764..15774
                     /gene="gap"
                     /locus_tag="TV193_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEL1513094.1"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAHL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDKFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKDVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            16318..17172
                     /locus_tag="TV193_000878"
     CDS             16318..17172
                     /locus_tag="TV193_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEL1513095.1"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            17382..18578
                     /locus_tag="TV193_000879"
     CDS             17382..18578
                     /locus_tag="TV193_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEL1513096.1"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLVLPVDSKEANAF
                     ADYTEVKVTEGEAVDTGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            19001..19522
                     /locus_tag="TV193_000880"
     CDS             19001..19522
                     /locus_tag="TV193_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1513097.1"
                     /translation="MNYHFDASKLKLGMRTFKTGLAVFFVLLLFHFFDFQGLQIGALT
                     AVFSLRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQGAFWVTLVFVPILTMLT
                     IMFNVAFNNQSGIIGAVAALLIITLSIPTGEAFMYVIARVFETFCGVFIAILVNTDVE
                     LIRNKWLSRKLKK"
     gene            19598..19969
                     /locus_tag="TV193_000881"
     CDS             19598..19969
                     /locus_tag="TV193_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1513098.1"
                     /translation="MKEKELRRSMAVFPIGAVMTLTDLSARQIRYYEDQELIKPERTE
                     GNRRLFSLNDMDRLLEIKDFLDEGLNIAAIKREYAERQDKLMQKQKVLTDADVRRILH
                     DELLNQGGFSTPSQHIGNFRI"
     gene            20006..21352
                     /gene="glnA"
                     /locus_tag="TV193_000882"
     CDS             20006..21352
                     /gene="glnA"
                     /locus_tag="TV193_000882"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEL1513099.1"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGTVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKGGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
BASE COUNT         6260 a         4116 c         5009 g         6059 t
ORIGIN      
        1 acagttatgt caaggctgac tgtttgagta aaccaagagc tatgctaaga atgaagtagc
       61 tgatgagata tggtataata atcaagcagg tatccctttt agggcaatac aagaaagagg
      121 aatgactaag aatgatagaa atttttgata cccatacgca tttgaatgtg gatcatttta
      181 gtggtaaaga ggaagaggaa ttagcacttg ctaaggagtt tggggttagc taccataatg
      241 tcgttggctt tgatcaggag actattgatc aagcccttac cttagctgat gcttataggg
      301 aggtctatgc aacgattggc tggcacccga ctgaggctgg ctcttacaca caggcggttg
      361 aagatagtct gattgcttgc ttgaagcacc caaaggttgt tgccttagga gagattggct
      421 tggattacta ttggatggag gaccccaagg aggtacagat agaggtcttt aagcggcagc
      481 tacagcttgc taaggaccat gacctcccct ttgtggtgca tacgcgtgat gcccttgagg
      541 atacctatca ggtcttaaag gaggctggag tgggtcctag aggtggtatc atgcattctt
      601 actcaggatc acttgagatg gctcaacgat ttgtagatct gggtatgctg atttcctttt
      661 caggggttgt cacctttaaa aaggcggttg atgttcagga agcagcaaga cacctgccgc
      721 tggataagct cttggtggaa acagatgccc cctacctcgc cccagtacca aagagaggac
      781 gtgaaaacca taccgcctat acgcgttatg ttgttgagaa aatcgcggag ctacgtggtt
      841 tatcagtaga agagatagct gcagcaacga ctgccaatgc aaagagggtg tttagaattg
      901 actgagaagc ttaaaattca agaggttatt gtggtagagg ggaaggacga taccgctaat
      961 ttacagcgct tctatgatgt cgatacctat gaaacaaagg gctctgccat cactgatgag
     1021 gacttagaac gcattgatcg gcttaacaag ctgcgtggtg tgattgtctt tacggatcca
     1081 gattatcatg gcgagaggat tcgcaaactg attatgagag ctgtcccaac agctcgtcat
     1141 gcctttttac gtcgacatga ggctaagcca aggtccaaaa gtaagggacg ttccttaggt
     1201 gtggagcacg ctagctttga ggacctgcaa aaggctctgt ctcaggttac ccagtctttt
     1261 gatgacgaga gttattttga tattagtcag acagatttga ttcgtctagg gcttttattg
     1321 gcagctgata gccgcaagcg cagagagtat ctaggagaag tccttcgtat cggctattcc
     1381 aacggaaagc agctcctaaa gcgcctaaag ctatttggca ttaccctatc agaggttgag
     1441 gacgtgatga cctcctatca gactgagcaa tagatggcgc tagaaaggct gattggatca
     1501 aacaaaagag ccctgagact tcttgttctg gctccaaaaa attagataag aaatggtaac
     1561 aaggattgaa ttctgtattg ggcaggagtc agtcctttta actttcttag ataagcattc
     1621 tctgttctaa gacgttcatt ctccttgaag ttgctctagt tctccagatg ttctttgatt
     1681 gatgtcctct cttgcttggt ttccctcttg ttttatcaag aatagtataa ccattttcat
     1741 ctcttttttt gctgtggctc tgataaataa tagaaatatg ctacaataga tataaaacaa
     1801 tgaataggac atcaacatga gaattgcaga ttacagtgta accaagtcta tccttgatcg
     1861 ctatggtttt acctttaaaa aatcatttgg tcaaaatttc ttgacggata ctaatatttt
     1921 acagaagatt gttgatacgg ctgagattga caagtcagtc aacgtcattg agattggtcc
     1981 tggtatcggg gctttgaccg aatttttggc agaaagggct gcagaggtca tggcctttga
     2041 gattgatgag cgcttggtgc caatactggc tgatacgctt cgtgattttg acaatgttca
     2101 ggtggttaat caggatattt taaaggcaga tttacagacc cagctaaagc aatttagcaa
     2161 tccggacctt cctatcaagg tggtagccaa tttgccctat tacatcacta cacccatttt
     2221 gatgcacctg attgaaagta agattccctt ccaagaattt gtcgtcatga tgcagcgcga
     2281 ggtggcagat cggatttcag ctgagcccaa taccaaggcc tatggctctt tgtctatagc
     2341 agtccagtat tatatgaccg ctaagatagc ctttgttgtt cctaggactg tttttgtgcc
     2401 agcaccaaat gtggattcgg caattctgaa gatgactcgt cgtgaccagc ccttgattga
     2461 ggttcaagat gaggatttct tttttagggt gtcacgagta ggctttgtgc atcgcagaaa
     2521 gacgctttgg aataacttgg ttagccattt tggcaaggct gaggacacaa aggcaaggct
     2581 tgagcaggga ctagctctag ctggaatcaa gccttctatc cgaggagaag cgctgtctat
     2641 tcaagatttt ggacggttag ctgatgccct aaagcaagta ggcttctagt gccttagtta
     2701 tgattgtagc ttgtcacagc aatcctgctg tggctttttt agatagtggt gggttcatct
     2761 tatctttggt gaaacttggg ctaaactgct gaattcgaat gatttttctg atataatggc
     2821 attattctag gataaaaaaa ggagttcatt tgcaaggcaa aatcattaag gctctggctg
     2881 gcttttacta tgttgagtca gaggggcagg tttatcaaac gcgggcgcgt ggcaatttta
     2941 gaaagcgtgg tcaaacaccc tatgtaggag atttagtaga attttctgct gaggacaatt
     3001 cagagggcta tattttagct attgctgagc ggaaaaatag tctggtgcgt cctcccattg
     3061 tcaatattga tcaagcagct gtcattatgt cagccaagga gcctgatttt aataccaacc
     3121 ttttagatcg ctttctcatt ttacttgagc acaaggccat ccaccctatt atttacattt
     3181 caaaaataga cctgcttgag cagccagaga gtatcgaagc cattggtcag cattatcgtg
     3241 cgattggcta tgattttgtg acgagcttat cacatctgct gccattatta gctggtaaga
     3301 caacagtatt tatggggcag acaggagttg gaaagtccac tttgctaaac cgtatcgcac
     3361 cagagctagc tcttgaaacg ggtgatattt cagacagtct gggacgagga cgccacacca
     3421 ctagagctgt tagcttttat gacgcttata atggcaaaat cgcagacacc cccggctttt
     3481 cgtccttgga ctatggcatt gataatgctg aggatctcaa cgaagccttt ccagagctta
     3541 gacgccttag ccatagctgt aaatttcgct cctgtaccca tactcatgag cccaagtgtg
     3601 cggttaagga agccttggga aatggtgagc tctggtctgt tcgctatcag aattaccttc
     3661 aatttctgag tgaaatcgaa aaccgtcgag aaacatatca aaaagttagt aaaagaaagt
     3721 aggtttaact atgtcatctc tgaaaattgc gccatctatt ttagcagccg attatgcttg
     3781 ctttgctgct gagctggctc gtattgaaaa aacagatgct gaatacgttc atattgatat
     3841 catggacggt cagtttgtgc caaatatcag ctttggagca gatgttgttg ctagcatgcg
     3901 caagcacagc aagctagtct ttgattgcca cttgatggtt gtgaatcctg agagatatgt
     3961 tgaggccttt gctcaggcag gagctgatat catgaccatt catgtggaga gcactcttca
     4021 tagtcatggc gccttgcaaa agatcagggc tgccggcatg aaggctggtg tggtcattaa
     4081 tcctgggaca cctgtctctg cggttgagcc tttattaagc ttggtggatc aggtgctgat
     4141 catgactgtt aacccaggct ttggaggaca ggcctttatt ccggaatgtc tggaaaaggt
     4201 tgcagctatt gctaaaatga gagatgaaag aggcttgagc tttgatattg aggttgacgg
     4261 tggtgttgat gataaaacca ttcgtgcttg ctatcaagca ggagctaatg tttttgtggc
     4321 tggctcctat ctgtttaagg cagcggattt ggcagctcaa gtgcaaacat tgagggcggc
     4381 ccttaatggt taaggtagcc ctctttgcag gtggggattt gtcctatttt acctgtgatt
     4441 ttgattattt tgttggaatt gatagaggaa gtctattttt gttagaaaat gggcttcctt
     4501 tgaatatggc tgtaggcgat tttgattcaa ttccccaagt agcctttgag gttgtcaagg
     4561 agcaagcaga gcttcttgtt caggctagtc ctgaaaaaaa tgatacggac actgaattag
     4621 ctctcaaaga ggtatttacc cgttttccag aggcagaggt tacgatcttt ggtgcttttg
     4681 gcggtagact agaccacttg ttatccaatg tctttttacc agcggatcca gagcttgcac
     4741 cgtttatggc acaaatttgc ctgcgggatc agcaaaatgc cattagctat cgatcctctg
     4801 gctggcagac gattaggcag gataaggaca tgacttatgt ggcctttatg gctgatggtg
     4861 atgctgactt gaccattaca ggtgccaaat ttgatttgac gacgtccaat ttctttaaga
     4921 aaaaggtata cgctagcaac gagttcattg atcagcctat taaggttcat gtgccaaagg
     4981 gctatttaat tattattcag agcaaagata ggagttagta tggaccttat tcttttcgtg
     5041 ttagtgcttg tgttgatagg acttgctgcc tattcatttg ttagcataaa gcatttgcag
     5101 agcagattag aaaaagcctt agacgataat gctgataatc tatcagatca gctaacctac
     5161 cagctggata tggcaaataa gagtcagctg ctagagctat caacagtgat gaatcgtcag
     5221 caaaatgagc tttttcagca gctgatggtt attcgtgata cgctgcatca gggcttggct
     5281 gaaaatcgcg accgctcaga ccagcgtttg gaaacgatga ctcaaagcct tagccaagct
     5341 gtcaagaacc tacaggattc taatgaaaag cgactggagg aaatgcgcca tacagtcgaa
     5401 gaaaagctag aaaagacatt gaagaatcga ttgcaaacct cctttgaggc cgtttcaaag
     5461 cagctagaaa gcgtcaatca gggtctagga gaaatgcgga ccgtagccaa agatgttggt
     5521 accctaaaca aggtcctatc caataccaaa accagaggaa tcctaggtga gctccagctt
     5581 ggtcagattg ttgaggacat catgacagct aaccagtatg aaagagagtt tgccacagtt
     5641 tctggctcaa gcgatcgtgt cgaatacgct atcaagctac ctggaaatgg gcaaggagac
     5701 tatatttacc tacctattga ctccaagttt cccttggagg attattacag gctggaggac
     5761 gcctacgagg ctggtgatag agctgctatt gagactagcc gaaaggctct tcttgcggcg
     5821 attaaacgtt ttgctaagag tattcatagt aaatacctga atccacctga aacaaccaat
     5881 tttgggatta tgtttttacc aaccgagggg ctctactcgg aggtggtgcg caatccggct
     5941 ttctttgata gccttcgtcg cgaggaaaat attgttgtag caggcccatc aaccttatca
     6001 gccctgctta attccttatc tgttggcttt aaaaccctta acctgcaaaa aaacgcagac
     6061 gatattagca agattttagg caatgtcaaa ttagaatttg aaaaatttgg cggcctgctt
     6121 gctaaggcgc aaaagcagct caacactgct aaccataccc tagaccagct gatgtcaacc
     6181 agaaccaaag cgattgttcg tgctctggct actgtcgaag gctaccaaga ccagtcaacc
     6241 caatccttat tacatatacc cttattagaa gaggcagacg atgaagatta accaaatgaa
     6301 aaaagaccag ccttttgaag gcttttacct gataaaatca gcagaagtca gaaaaacaag
     6361 ggctggcaag gattttattg cttttacctt tcaagatgat actggtgaga tttcaggtaa
     6421 tttgtgggac gcccagccct ataatgttga ggaatttgtc gcaggtaaga ttgtctttat
     6481 gaaaggccgt cgtgaggtct ataatggcac tcctcaggtt aaccagatta ccttaagaaa
     6541 tatccggcct ggggagccta atgacccaaa ggaatttaaa gaaaaggcac ctgtcagtgt
     6601 tactgaggtt cgtgactacc tagatcagat gctctttaag atcgaaaatg cgacctggca
     6661 gaggattgtc agagcgcttt accgcaaata tgataaggag tttttcactt atccagcagc
     6721 caaaaccaat caccatgcct ttgaatcagg cttggcctat catacagcaa cgatggttag
     6781 actagcagat agcattggag atatttatcc agagctaaat aaaagcctgt tatttgcagg
     6841 cattatgctg catgacctag ccaaggtact tgagctgaca ggcccagaca ataccgaata
     6901 tactatccga ggcaatctga taggacatat cgccctcatc aacgaagaga ttacaaagac
     6961 catcacagag ctgaacattg atgacaacaa agaagaggtc accgttttac gccatgtaat
     7021 cttaagtcat catggccaat tagaatacgg cagccctgtt cgtccgcgca ttatggaggc
     7081 agagattatt cacatgattg acaacattga cgccaatatg atgatgatgt caacagctct
     7141 cagtcgtatt ggcgagggag aaatgaccaa tcgtattttc gctatggata accgatcctt
     7201 ttataaacct aaatattagc aaggatcata ataaaaaacg aacattttgc agttgaatgt
     7261 tcgttttttc gttatgttat gatataatag tagagaatat ataaataatg gggaacatat
     7321 gaaattaaga cgaagtgaac gcatggttgt gatatctaat tacctgatta acaaccctta
     7381 taagctaaca agtttaaata cctttgccac aaaatatgag gcagccaaat catctatttc
     7441 agaagatatt gccattatca aaaaagcctt tgaagaatct aatattggag agattgacac
     7501 tctaacaggg gcaagtggag gtgtcatttt tacgccaagc atttcagagg cagaggctcg
     7561 ctcaatcgta gaagagctgt gtcagcggct ttcagaaagt aaccgcattt tacctggtgg
     7621 ctatatctat ctgtctgatt tattaagcac accaaagctc ttgcagaata tcggtcgcat
     7681 tatcgctaat gcttttaagg ggcaaaaaat tgacgcggtg atgacagttg caactaaggg
     7741 ggttcccttg gctaatgcgg ttgcaaatat tctgaatgta ccctttgtga ttgtcaggcg
     7801 cgacttaaaa atcacagaag gttcaaccgt ctcagtcaac tacgctagtg cctcaagtta
     7861 tcgtattgaa aaaatgtttt tatcaaagcg aagcttaaag ccaaacagtc gagtcttgat
     7921 tgttgatgat tttttaaagg gtggtggtac aatcacaggc atgatgagcc tgttaacgga
     7981 gtttgatagt acattggtgg gtgtagctgt ttttgcagaa aatgcacaat cagagcgcga
     8041 acaaatgtcc ttcaagtcac tattaaaggt ctccgaaatt gatgtcaaaa ataatagggt
     8101 cgttgttgaa gtaggaaata ttttcgataa ataaatcgaa cgtaggtgga aaaataaaag
     8161 gggattaatc atggagcaag aaaactcaag aacaaagcat gttaaaagta ccattgcttt
     8221 gacatcaacc attgccctat tagggacaag cgttggtgta tcacatcagg taaaggcaga
     8281 cgatgctaag tcaggcgatg ccaatacaag caataccagc gaagctacgc tagctaagcc
     8341 agaaacgctt gaggaggcag tccttgcggt aaaggctaca gaagaaacac tcagtgagcg
     8401 taaaaaagaa ttagctgaga ctaatacaaa tatcgcggaa acagagggcg aaatcgcaaa
     8461 cctagaagca actaaaaaag aacagatagc tgagcttgcc aaggctgagg agctacttga
     8521 gacttactcg tccatgagtg aggaagacct agccaagtca attgaaaagc atgagacaga
     8581 gctagagaca attaacacag aactagagaa ggcgactact gagagtcaag ctcaggcaga
     8641 ggcagtggct aagcagcaag aaacgatcgc agcagaggct acaaaggccg accagctagc
     8701 tacccagcta acagcagcag agcaaaaggt ctcagacctt aacacgatga ttagccagcc
     8761 ggaagctatt gtctcagaag ctcaagctgc aaaagaagag gtcaagcgca tttctgatga
     8821 cctagcaaag gctacagcaa atctagctac tgttaaggag acagtccaca gccagctaac
     8881 ctcagaccta gcagccaaca aggcagccct ggcagctaaa gaggcagagc tgcaaaggct
     8941 tcaaaatgga gttgccactg cccaattgaa cgttgctggc agcaataaat taattcttcc
     9001 aaaagactac ccaattgagg agattaaaaa gctagcagcc agtggttata tcggaacagc
     9061 agcatataat caatattatc aggcagttaa ggatacaatg attgcaaagg cagagccggg
     9121 tgctgccatg aatcagtatg ttgatattcc tgaggacctc aatcgtgttg ttgaccctga
     9181 caacctatca caagaggttc aaaatgagct agctcagttt gcagctcaaa tgattaatga
     9241 tgtccgcaag cagctaggac ttgtccctgt aacagtaaca gtcggctcac aggagtttgc
     9301 tcgcctgcta accaagagct acaaggaaac acatcaaaat actcgacctt cctttgtcta
     9361 tggacaagta gatgcttcag gtcatcgcgg tgtaggtccg catgatcaaa cgattattga
     9421 agaatctgct gtaaaggtag gacttcgtca aaaagatgac aacatgtacg aaaaccttgg
     9481 tgcctttaac gaggttcaca ctgtcaacgg tatcaagcgc ggcatctatg acagcattaa
     9541 gtatatgctg tttacagatc acctgcatgg gaacacctat ggtcatgctg ttaacttcct
     9601 gcgtgttgat aagactgacc ctaatgcacc tgtttaccta ggattttcaa caagtaatgt
     9661 tgagtcctta aatgagcatt ttgtgatttt cccagagtca gatattgtgg acgctactcg
     9721 ttttagcacg actgaaattc caaaatcagg tcaggtgatt gatcgctcag caagcataca
     9781 ggcattgaca aatgatattg cttcgatcaa gggcaagatt gcgtctcttg aaagcagatt
     9841 agctgatcct tcctcagaag ctgaggtcac agctgcgcag gcaaaaatca gtcagctgca
     9901 acatcagcta gaagcagccc aagccaaatc tcataaattg gatcaacagg ttgagcaatt
     9961 ggccaataca aaagattctc tacgcacaca gttgcttgct gccaaagaag agcaggcaca
    10021 attgaaggct aatctagata aggccttggc cttgctagcg tcttcaaagg ctacgcttca
    10081 taagcttgaa gcagctatgg aagaggctaa ggcaagagta gccggcttag ctagtcagaa
    10141 ggctcagctt gaggatctgc tagcctttga gaaaaatcct aatcggatcg agcttgcaca
    10201 ggaaaaggta gccgcagcca aaaaggcttt agctgataca gaggataagc tcttagctgc
    10261 tcaggccagc ctgtctgatt tgcaggctca aagagcaaga ctccagcttt ctattgcgac
    10321 aattgaacaa caattagtac tattgaagaa tttagtccaa gaaaagcaaa ggctcagact
    10381 tgaggctgaa aggctaaata gcatgtcaga aacaagacag cttctcaatc agctagcgcc
    10441 gcaggctgca aaagcaggtg tcggctcaga attggttgct acaggtcttc ttgtctccaa
    10501 ggttgcctca gctatcgcta agcaatcacc gacaagccat tcctatggag caggagcagc
    10561 atcacatgca gctgttgatg acaacacaca gcgtgctgtt caggctggta tggtcatgct
    10621 ggcagctgcc ggcttagcaa cggttaagct caaaaaaggc agcaaaaaac gctaagccta
    10681 gcttaaaaag catttgacac aaggtatcgt ctatgttatt atattagacg gtacttttta
    10741 cttttggtct ctcaagagtg tacagagacg tgctgacaat tgttgcaaaa agtgcaccag
    10801 atataggctg tcaccaagtg ctatatcaac caaaattaaa aaaacaggag aatgtagatg
    10861 cctacaatta accagttggt acgtaaacca cgtaaatcta aaattgagaa atcagattcg
    10921 ccagctttga acattggcta caacagtcat aaaaaagttc atacgaagct tgctgctcca
    10981 caaaagcgtg gtgttgcgac tcgtgttgga acaatgacac ctaaaaaacc taactcagcc
    11041 cttcgtaaat ttgcgcgtgt acgcttaagc aaccttatcg aagtaacagc ttatatccca
    11101 ggtattggcc acaacctaca agagcacagt gttgtgctta tccgcggtgg acgtgtaaag
    11161 gaccttccag gggtacgcta tcatatcgtt cgtggagcac ttgatactgc aggtgttgca
    11221 gaccgtaagc aaggccgttc taagtacggt gctaaacgtc caaaaggata atagaggagg
    11281 gataagaaac aatgagtcgt aaaaatagag cgccaaaacg cgaagtatta ccagatccat
    11341 tatataactc aaagcttgtg acgcgtctta tcaatcgtat tatgcttgat ggaaaacgcg
    11401 gaactgcatc atcaatcgtt tatgatgctt ttagcgaaat caaagaagca acaggcaacg
    11461 atgctcttga agtatttgaa acagctatgg acaacatcat gcctgtgctt gaagtgcgtg
    11521 cacgtcgtgt cggtggttca aactatcagg ttccagttga ggttcgtcca gagcgtcgta
    11581 caacacttgg tcttcgttgg ttggtaactg catcacgtgc tcgtggtgaa cacactatga
    11641 aagatcgtct tgctaaagag attatggatg ctgcaaacaa caccggtgcg tcagtcaaga
    11701 aacgtgagga tactcataag atggctgagg ctaaccgcgc ctttgcacac ttccgttggt
    11761 aagaataaga tacgaaggtg tacagaacgc atagtgaaga taggaagctt gacgaagaga
    11821 tttttatctc taggaaagct tatctttttc acacagcgtt tagcctgagt tcagttttag
    11881 gctgttttag tgtgagacaa atgctagccc aaatcgggaa attgacgcag aagcgatcat
    11941 ttccagaaga ttttatcttt ttggcagaca tttgtcgcta aaattcaact aatctaagat
    12001 gtgagagtgt taagcaagtt ctagacaaac tgatctatta tcttttttgt cagtgacttg
    12061 cagctcaaac tcagttacaa tcaagatgta tagacaaaga gagcaagatt ttaatagaaa
    12121 attctcacct tcaagatgag ttattgtttt gatcggattg ctcttaagtc gggttttggt
    12181 ttgcaaacat actaaatgct atctatcaaa catatcttag gaaacgggta ggcctctgcc
    12241 tatccgtttt taatgaatag tgttataata agatgtaaat aaaaaatata ggagaaaaaa
    12301 cctaatggct cgcgaatttt cactagcaaa aactcgtaat atcggtatca tggctcacgt
    12361 tgatgctggt aagacaacta caacagagcg tatcctttac tacaccggta aaatccataa
    12421 aatcggtgaa acacacgagg gtgcatcaca aatggactgg atggagcaag agcaagagcg
    12481 tgggatcaca atcacatctg ctgctacaac agcgcaatgg gatggacatc gtgttaatat
    12541 cattgacaca ccagggcacg tggacttcac cattgaagta caacgttcgc tccgcgttct
    12601 tgacggtgca gtaaccgttc ttgactcaca atcaggtgtt gagcctcaaa cagaaactgt
    12661 ttggcgtcaa gcaactgaat acggtgttcc acgtattgtt tttgccaaca agatggataa
    12721 gatcggtgct gacttccttt actcagtaca aacccttcac gatcgtcttc aagcaaatgc
    12781 tcacccaatt caattaccaa tcggttcaga agatgatttt cgtggtatca ttgacttgat
    12841 caaaatgaag gctgaaatct acaccaatga ccttggtaca gatattcttg aagaagatat
    12901 tcctgaggaa tacctagagc aagctcaaga atatcgtgaa aagcttatcg aagcagttgc
    12961 tgaaactgac gaagatttga tgatgaaata ccttgaaggt gaagaaatca ctaacgaaga
    13021 acttgttgct ggtatccgta aagcaacgat caacgttgag ttcttcccag tgctttgtgg
    13081 ctctgccttc aaaaacaaag gagttcaatt gatgcttgat gcggttattg cataccttcc
    13141 aagcccactt gacattccag caattaaagg ggttaatcct gatactgacg ctgaagaaga
    13201 gcgtccagca tctgatgaag agccatttgc agcccttgcc ttcaagatca tgactgatcc
    13261 atttgtaggt cgtttgacct tcttccgcgt ttactctggt gttcttaaca gtggttcata
    13321 cgtgatgaat acctcaaaag gtaagcgtga gcgtatcgga cgtatccttc aaatgcacgc
    13381 taacagccgt caagaaattg aaacagttta cgctggtgac attgctgctg ctgttggttt
    13441 gaaagacact acaactggtg actcattgac tgatgaaaaa gcaaaaatca ttcttgagtc
    13501 tattgaggtt ccagagccag ttatccaatt gatggtagag cctaagtcta aggctgacca
    13561 agataagatg ggtattgctc ttcaaaagct tgctgaagaa gatccaacct tccgcgttga
    13621 gacaaacgtt gagactggtg aaacagttat cgctggtatg ggtgagcttc accttgatgt
    13681 ccttgtagac cgtatgcgtc gtgaattcaa ggttgaagct aatgtaggtg ctcctcaggt
    13741 atcttatcgt gaaaccttcc gcgcttctac acaggctcgt ggcttcttca agcgtcagtc
    13801 tggtggtaag ggtcaattcg gtgacgtttg gattgaattt acgccaaatg aagaaggtaa
    13861 aggatttgag tttgaaaatg ccattgtcgg tggtgtggtt cctcgtgaat ttatcccagc
    13921 cgttgaaaaa ggcttgattg agtctatggc taatggtgtc cttgcaggat acccaatggt
    13981 tgacgttaaa gctaagcttt acgatggttc ataccatgat gtcgactcat ctgagactgc
    14041 cttcaagatt gcggcttcac ttgcccttaa agaagcagct aaaacagcac agccagctat
    14101 ccttgagcca atgatgcttg ttacaatcac agctccagag gataatcttg gagatgttat
    14161 gggacatgtg acagctcgtc gtggacgtgt tgatggtatg gaagcacatg gtactagcca
    14221 aattgttcgt gcttatgtgc cacttgcaga aatgtttggt tatgcgactg ttcttcgttc
    14281 tgcaacgcaa ggacgtggta cattcatgat ggtatttgac cactatgagg atgttcctaa
    14341 gtcggttcaa gaagaaatta tcaagaaaaa taaaggtgaa taatcacccc taagaggctg
    14401 tggatagtat cccagccttt ttgatgtgtt acaacagatg ggcggtgcag caattgatca
    14461 aagcaatgac agaaaaatca agccctatca ggcataaacg tttaggaaaa ggccttaaga
    14521 aagcgctttt aacaacatta agcgacactt ttggctgccc taaaaagctc tttgctgtct
    14581 caatattgat ggagaagcag tcttttgaaa atgggtaata tgtttgcatt ttttctgaaa
    14641 tagttatata atagttacgt tgaagggttg ttgcaggaat ctgcaagtta atcttttcac
    14701 aataggtagg gattagtccc tttaataata attcttttga ttttcataag gaggaaatca
    14761 ctaatggtag ttaaagttgg tattaacggt ttcggtcgta tcggtcgtct tgcgttccgt
    14821 cttatccaaa atgtagaagg tgttgaagta actcgcatca acgacttgac agatccagcc
    14881 atgttagcac atcttttaaa atatgattca actcaaggac gctttgatgg cgacgttgaa
    14941 gtagtagaag gtggatttaa cgttaacggt aaatttgtta aggtttctgc tgaagctaac
    15001 cctgaaaaca ttgactgggc ttcacaagaa gtagatatcg ttttggaagc aactggtttc
    15061 ttcgcttcaa aagctggtgc tgaaaagcac ttacacgcta atggtgctaa gaaggttgtt
    15121 atcactgctc ctggtggaaa cgatgttaaa actgttgttt tcaacactaa ccacgaaatt
    15181 cttgatggta ctgaaacagt tatctcaggt gcttcatgta caactaactg tcttgcccca
    15241 atggctaaag ttcttcaaga caaatttggt gttgttgaag gcttgatgac aactatccat
    15301 ggttacactg gtgaccaaat gactcttgat gcaccacacc gtaagggtga tttccgtcgt
    15361 gcacgtgctg cagctgtgaa cattgttcct aactcaactg gtgctgcaaa agctatcggt
    15421 cttgttattc cagagcttaa cggtaagctt gacggtgctg cacaacgtgt tccagttcca
    15481 acaggatctg ttactgagtt agtatctgta cttgaaaaag acgttacagc tgacgaagtg
    15541 aatgctgcaa tgaaggctgc tgcaaacgac agttttggtt acactgaaga tcaaatcgta
    15601 tcaagcgacg ttgtaggtat ccactatggt tcattgtttg atgcaactca aactaaggta
    15661 ttgacagttg atggtaaaca attggttaaa actgtttcat ggtatgacaa cgaaatgtca
    15721 tacactgctc agcttgttcg tacacttgag tactttgcaa aaattgctaa ataatgacta
    15781 gagggcctag tttacctagg ctcttttttg tgtcatgata aaggttgctt atccctcatt
    15841 ggctagctta ttgctgaact tgcacttagg cttaagctgc acataggata agtttttttg
    15901 ctaacgcttt agtgattagc tgttctcaga gagggtcatt ttagaaacct tcttaaggtg
    15961 atatggctat caagctgcct tctttgaact gctatgctta ggctttgagt ttaggtctta
    16021 aaagctttag gtgagttttt cgttataatt aactgcataa agcatggctt taagctcatt
    16081 tccagcgcaa ataccttttt tctttgcaag atgtcaaaga gaagtactgt aatggctcgg
    16141 gcttatctac attttttgct cagctatttt tagctgtttt ttagctatgg ctccatgaaa
    16201 ttgtgaagcg ttttcatttt tattggttat agtcttgaca atctgaaatg atggtaataa
    16261 aatgagaggt ggataaataa ccgtacttaa taatgtatgg aatattagga ggattttatg
    16321 acatctaaaa aaattcttaa ccttgtgtct ttagggttat cgttggtttt aatctctggc
    16381 tgtacgacaa atggagagaa aaaagcagct cctagtcaag acaaggataa gcaagaaaag
    16441 gttgtccgtc taaccaatga tcagctaagg gctagggaaa ataccatggc cacactctgg
    16501 tatcagcagt ctgaagaggc taaggctctc tacttacagg ggtaccaagt ggctaagcag
    16561 cgcttagata cattattgag tcaagcaact gataaaccat actctattgt tttggacatt
    16621 gatgagacag tgctcgataa tagtccttac caggctaaaa atattaaaga gggcacaggc
    16681 tttacgccgg attcttggga taaatgggtc caaaagaaat cagccaaggc agtagcaggt
    16741 gctaaggact tcttgcagta tgcaaatgac aagggcgttc agatttacta tgtttctgac
    16801 agaacgacta agcaagtaga gccgactatg gaaaatcttg aaaaagaagg tattccagtg
    16861 caaggcaagg atcatttctt gttcttagag gagggtgtaa aatcaaaaga gggccgtcgt
    16921 caaaaggtgc aagaaacaac aaatctagtg ttgttatttg gtgacaattt gcttgatttt
    16981 gcagagtttt ctaagacctc tcatgaagat agaagaaagc ttttggatca gctgcatgca
    17041 gagtttggca gcaagtttat catcttccct aatccaatgt atggatcatg ggaaagcagt
    17101 gtctataatg gtcaaaaatt agacagtgaa ggccaaatca aagcacgtga caaggcttta
    17161 gaggcttatt aaaagccctg atttgcgtga ttgctatgac tatgttgtgg cttcctgcct
    17221 gcttaggtga ttgtgatctg ctaaaaagag gtttacccaa gggatttttc aagcgctttg
    17281 aaaaattgtg aaatagttaa tttattgttt tcagatttta tccttatcaa aagaattgtg
    17341 ttataataga gtgtactaaa aaatattaag gagtctatga aatggctaaa ttgactgtta
    17401 aagaccttga cctaaagggt aaaaaagtgc tcgttcgcgt tgactttaat gtccctttga
    17461 aaaatggtgt tattacaaac gataaccgta tttctgcagc acttccaaca atcaaataca
    17521 ttattgagca tggtggtcgc gctatccttt tctcacacct aggacgtgtg aaggaagagg
    17581 cagacaagga aggcaaatca ttggcgccag tagcgaaaaa cttggctgaa aagcttggtc
    17641 aagaggttat tttccctggt agcactcgtg gggcagagct tgaagctgct attgatgctc
    17701 ttgaggatgg acaggttctt ttggttgaaa acactcgctt tgaggatatt gacggtaaaa
    17761 aggaatctaa aaacgatcca gagcttggta aatactgggc atcactagga gaaggaatct
    17821 ttgttaatga tgcctttggt acagctcacc gcgctcatgc gtcaaacgtt ggtatctctg
    17881 caaatgttga aaaagcagtg gctggtttcc ttcttgaaaa tgaaattgcc tatatcaagg
    17941 aagctgttga gactccagag cgtccatttg tcgctattct tggtggttca aaggtttctg
    18001 ataagatcgg tgtgattgaa aaccttcttg aaaaagctga taaggtgctt atcggtggtg
    18061 gtatgaccta taccttctac aaagctcaag gtattgaaat tggaaactca ctttgtgaag
    18121 aggacaagct tgatgtggca aaatcacttc ttgaaaaatc aaatggcaag cttgttttac
    18181 cagttgattc caaagaagca aacgcttttg cagattacac tgaagtgaag gtaactgagg
    18241 gtgaagcagt tgatacaggc ttccttggtc ttgacatcgg tccaaaatct atcgctaaat
    18301 ttgatgaagc cctgacaggt gctaaaacag ttgtttggaa tggtcctatg ggtgtctttg
    18361 aaaaccctga tttccaagaa ggtacaattg gtgtgatgga cgctattgtg aagcagccag
    18421 gtgttaagtc aatcatcggt ggaggtgatt cagcagcggc agccatcaac cttggacgtg
    18481 cagataaatt ctcatggatt agtacaggtg gaggtgcttc aatggagctt cttgaaggta
    18541 aggagcttcc aggcttagca gctcttacag aaaaataagc tgataccatt tcggtgctgt
    18601 cagtcgcagg ctgctatatg gtctgttaag ggctaagaca gctgaaggct cacaaaggtg
    18661 gcttatgttg ctggcggtgc ttatgctaat tgttatgatt aacaagctgt caaaggatag
    18721 gctagagcct gctgtaccag tctatcaggc cttgctgtca gctactaaat gaatgagtca
    18781 gaaaaaggtg ctatgtaggt gcctttttct gcgttttgct ttaggctgat agtgagtttg
    18841 cttgaagtca agactggctt catgcaggct tcagagtctt tgctaggaat gctataaggt
    18901 gggttctgag cttatctatt taggatatgt gacaaatgct gttaaaatat gttacactag
    18961 cattagcttt aatttcaata gaaagtatct gatataggtt atgaattatc attttgatgc
    19021 ctctaagtta aagttgggca tgcgtacgtt taaaactggc ttagctgtgt tttttgtttt
    19081 gcttttgttt catttttttg attttcaggg cctgcagata ggggccttga cagctgtttt
    19141 tagcttgaga gagagctttg ataagacgat ctcctttggc acctctcgta ttttaggaaa
    19201 ttcgattggt ggtttttttg cgattatatt ttacctgctt gatactcttt ttcagggcgc
    19261 attttgggtt accttggttt ttgttccgat attgacgatg ctaaccatta tgtttaatgt
    19321 ggcttttaat aatcaatctg gcatcatcgg tgcagttgct gctcttttaa ttatcacctt
    19381 gtctattcct actggcgaag cttttatgta tgttattgct cgggtttttg aaaccttttg
    19441 tggggttttt attgccattc ttgtcaatac agacgtggag ctgattagaa ataagtggtt
    19501 gagcaggaag ctcaaaaaat gatgtcagaa aacataacat gtgaccttga cagtttatta
    19561 aaatcaacct ataatagggg tgtgaaagga agttttcatg aaagaaaaag aactcagacg
    19621 ctcaatggca gtctttccga tcggtgcagt tatgaccttg acagatctat ctgctcggca
    19681 aattcgctat tatgaggacc aggagctgat aaagcctgag agaacagagg gcaaccgtcg
    19741 cttgttttcc ttaaacgata tggatagact tcttgaaatc aaggactttt tggacgaagg
    19801 attaaatatt gcggcaatta agcgagaata tgctgaacgc caggataaat taatgcaaaa
    19861 gcaaaaggta ttgactgatg cagatgtgag acggatctta catgatgagc ttcttaatca
    19921 aggtggcttt tccacccctt cacagcatat tgggaatttt cgtatctagc atacgactgg
    19981 catgaaagaa aaaggagatt gattaatggc aatcacagca gctgatgttc gtcgcgaggt
    20041 caaagaaaag catgtgacct ttcttcggtt gatgtttacg gacattatgg gtgttatgaa
    20101 aaacgttgag atacctgcaa ctgaggagca attagataaa gtcctatcta ataaggtcat
    20161 gtttgatggc tcctcgattg aaggctttgt gcgtatcaat gaatcagata tgtatctcta
    20221 tcctgattta gacacttgga tcgtctttcc ttggggagat gaaaatggaa ctgttggtgg
    20281 cttgatttgt gatatttaca ctgctgaagg caagcccttt gctggtgacc cacgtggcaa
    20341 cctaaaaaga gccttgaagc atatggatga ggttggctat cagtccttta accttggtcc
    20401 agagccagaa tttttcttgt ttaagataga tgaagctgga gaaccaacgc ttgaggtcaa
    20461 tgacaaggga ggctattttg acctcgctcc gattgatctg gcagacaata cccgtcgtga
    20521 aattgttaat gtcttgacca aaatgggctt tgaggtcgaa gccagccacc atgaggtagc
    20581 tgtcggtcag catgaaattg actttaaata tgcagatgcc ttgaaggcct gtgataatat
    20641 tcagatcttt aagcttgtgg tcaaaaccat tgcgcgtgag cacgggctct acgctacctt
    20701 tatggcaaag ccgaaatttg gtattgccgg ctcaggtatg cattgtaaca tgtccttatt
    20761 tgataaaggg ggcaacaatg ccttttatga tgaaaatgat aagcgtggca tgaagctatc
    20821 agatgatgcc tattatttct taggtgggtt gatgaagcat gcttacaatt acaccgctat
    20881 cacaaatcca acggttaatt cctacaagcg cttggttcct ggttatgagg ctcctgttta
    20941 tgttgcttgg gcaggaagca atcgttcacc tcttattcgt gttcctgctt ctcgtggtat
    21001 ggggactcgt ttagaattgc gttcggttga tccaacagcc aatccttatt tagcacttgc
    21061 cgttttacta gaggcaggct tagatggtat cattaataaa attgaagcgc cggcaccgat
    21121 tgaggctaat atttacatga tgacagcaga ggagcgcaat gctgctggca ttgttgattt
    21181 accgtcaaca ctccataatg ctctaaaggc gcttcaaaag gatgaggtca ttcaaaaggc
    21241 tttaggtgat catatttaca ccaacttttt agaggcaaaa cggattgaat ggtcttccta
    21301 tgcgaccttt gtttcgcaat gggagattga taattactta cacaactatt agaaaatcaa
    21361 aactcactca gctttttgag tgagtttttt atgcttttat tcagcagata tggttattta
    21421 tacttatcgt tccttttata cgct
//
LOCUS       DARYXS010000029        21349 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.029, whole genome shotgun sequence.
ACCESSION   DARYXS010000029 DARYXS010000000
VERSION     DARYXS010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21349
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.029"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(200..457)
                     /locus_tag="TV193_000883"
     CDS             complement(200..457)
                     /locus_tag="TV193_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEL1513100.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
     gene            complement(994..3033)
                     /locus_tag="TV193_000884"
     CDS             complement(994..3033)
                     /locus_tag="TV193_000884"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEL1513101.1"
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVERMADFLKANRLSYDAI
                     EGFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVD
                     DIEFREVKGEEYVYVTKHEAGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVH
                     SLIVLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKER
                     QEMIIAQIRAIEAEQKVQVDIDEDLLNEVLNLVEYPTAFMGSFDPKYLEIPEEVLVTS
                     MKNHQRYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQ
                     KLSIEDLVAKLAHVTFHEKIGSVAEHMERTKVIAAFLADQAGLSEAEKSAVARAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLTGEAAAVATAIREHYLPNSAEGELPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYE
                     LSFDSLTYQHKAEVLDFICARVDKMMGSAIPKDIREAVLASSSFVVPELLARAEALAA
                     ASQLDTYKPAVESLSRVFNLAKKAVDAVLIDASLFENDYERALAQAVDSLVLSGSAKE
                     QLAQVFALSPVIDDFFDHTMVMTEDEAIRRNRLALLAELVKKVETIAAFDRLNTK"
     gene            complement(3399..4310)
                     /gene="glyQ"
                     /locus_tag="TV193_000885"
     CDS             complement(3399..4310)
                     /gene="glyQ"
                     /locus_tag="TV193_000885"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEL1513102.1"
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLER
                     LGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFE
                     IFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVA
                     KTFVAERKKLGFPLLDDASRVALLAED"
     gene            complement(4676..5209)
                     /locus_tag="TV193_000886"
     CDS             complement(4676..5209)
                     /locus_tag="TV193_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEL1513103.1"
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFL
                     TLLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREE
                     NRLLSEVIIPNGTRPKS"
     gene            complement(5476..5700)
                     /locus_tag="TV193_000887"
                     /pseudo
     CDS             complement(5476..5700)
                     /locus_tag="TV193_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(5730..6569)
                     /locus_tag="TV193_000888"
     CDS             complement(5730..6569)
                     /locus_tag="TV193_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEL1513104.1"
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYV
                     DLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTAT
                     ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWGPLGQGEIFADDTMQALAKKYNKTV
                     AQLALAWSIAEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDT
                     KDF"
     gene            complement(6656..7804)
                     /gene="nagA"
                     /locus_tag="TV193_000889"
     CDS             complement(6656..7804)
                     /gene="nagA"
                     /locus_tag="TV193_000889"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEL1513105.1"
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGYWTATVDDQAEVID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHL
                     EQVSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAK
                     GLIKKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYTEAKKAVAAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRA
                     GGSPDGDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHM
                     SSYVPAASVGIEDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     gene            complement(7921..9562)
                     /locus_tag="TV193_000890"
                     /pseudo
     CDS             complement(7921..9562)
                     /locus_tag="TV193_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            9753..10499
                     /locus_tag="TV193_000891"
     CDS             9753..10499
                     /locus_tag="TV193_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513106.1"
                     /translation="MRKPTKETHYLIISLLTIAIAGGAYLIFSSLSPKPATITTQSKG
                     YELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAISLKHNQEDV
                     AIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETATP
                     AAEKNIAPAPAAPQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAPENPEPTPSPNP
                     QPNPQPETNTPSPQPPATEQSENTAPAGQN"
     gene            complement(11105..11947)
                     /locus_tag="TV193_000892"
     CDS             complement(11105..11947)
                     /locus_tag="TV193_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1513107.1"
                     /translation="MTWKIVSDSGCDIRALKSQSNHLRFERVPLTLQIGSDIFRDDDG
                     LDIDQMMETMYQSSKPATSSCPSPDAFLQAYRGADNVIAITITGTLSGSHNSARLAQN
                     DLLEENPNANIHVIDSLSAGGEMDLIVLELERLINQGLSFDEVVEKITAYQEKTRLVF
                     VLAKVDNLVKNGRLNKLIGKVIGLLNIRMVGQASKEGTLELLQKARGQKKAVSAVLEE
                     IQKAGYKGGRVFISHAKNPKICEQIAEKIRAIYPEAEIQTSPASGLCSFYAEAEGLLM
                     GYEV"
     gene            12079..12636
                     /locus_tag="TV193_000893"
     CDS             12079..12636
                     /locus_tag="TV193_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1513108.1"
                     /translation="MAGKPISKQSLQNLAHCNQESRRLTREAIEIALLSLLEKKPLGH
                     ITISELVARAGVSRNAFYRNYSSKEDILECLLTSVIRRIFRGLKAFDLKTQAYQAWLY
                     LFTEAKKEATLLSIIFNHHLQQLLTQMVTKRLRAYQKWQEKKLSHYALLFWSNAIVSV
                     LSNWISDDMVVPAEEMAAMGLPLLA"
     gene            complement(13047..13871)
                     /locus_tag="TV193_000894"
     CDS             complement(13047..13871)
                     /locus_tag="TV193_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1513109.1"
                     /translation="MIQLIAIDLDGTLLDSKKHIPKENIKAIQAAAQEGIKVVLCTGR
                     PQSGTRPYFEQLGLSDKEEYLILNNGCSTYRSPSWELLHYQSLTFSAIEHLYQLSQPF
                     SDIYLTLTGERDYLVIDSKVPDMVQADGDLVFTKVKATNLSQLSNSSQIIFQAMYMGE
                     KAALDTFEALVREKLSASFSVVRSQETILEVMPECVTKASALKELTADLKLRPDQVMA
                     IGDAANDLEMLAYAGLGVAMGNADEAIKKVADKVSLSNDQAGVAHAINQFALTKGS"
     gene            complement(13876..14490)
                     /locus_tag="TV193_000895"
     CDS             complement(13876..14490)
                     /locus_tag="TV193_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEL1513110.1"
                     /translation="MTIDMWELLSIIGTIAFALSGAIVAMEEEFDVLGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQRPEFACAFIAIILIMLFPKLVAKGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLAQPLSAVIVAAVLTGAGGGVVRDVLAGRKPTVLRSEIYAGWSIIA
                     ALVLYFKLATSNVECYLLVVLLTVMRMIGNKRQWHLPKIKWKED"
     gene            complement(14651..15523)
                     /locus_tag="TV193_000896"
     CDS             complement(14651..15523)
                     /locus_tag="TV193_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEL1513111.1"
                     /translation="MKKVMMSLLILATATLGACQASHQSDQPKQEQKEPQAKKGRLFL
                     SNMNSAKSQQEVRAALSHQLKEANVNAFMAGVQEYNSLVGKTGLTGAFTYQKQPDYDV
                     VAIDELWSQKQGNFIGTNCRINTFMLLKDSMTIAPTSSDDTLLFMDEDAITTSQLFTQ
                     AETERFKQLFSRVKTEATKDIQVHAKHMQEHFSAVSFNGPAKMLAVVIHDQLDGDYLF
                     IGHVGVLVEYKSKYLFVEKLSFQEPYQAILFDQKQDCYQYLYHKYKTYQTKTSAEPFL
                     MENNKAVNLASYRS"
     gene            complement(15734..16219)
                     /locus_tag="TV193_000897"
                     /pseudo
     CDS             complement(15734..16219)
                     /locus_tag="TV193_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            complement(16222..16488)
                     /locus_tag="TV193_000898"
                     /pseudo
     CDS             complement(16222..16488)
                     /locus_tag="TV193_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106440.1"
                     /note="catalyzes the reversible reaction of
                     dihydroxyacetone phosphate with glyceraldehyde 3-phosphate
                     to produce tagatose 1,6-bisphosphate; in Streptococcus
                     pyogenes there are two paralogs of tagatose-bisphosphate
                     aldolase, encoded by lacD1 and lacD2; expression of lacD1
                     is highly regulated by environmental conditions while
                     lacD2 specializes in an efficient utilization of
                     carbohydrate sources; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
     gene            complement(16490..17422)
                     /locus_tag="TV193_000899"
     CDS             complement(16490..17422)
                     /locus_tag="TV193_000899"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEL1513112.1"
                     /translation="MILTVTLNPSIDISYPLNRLTLDTVNRVDRTTKTAGGKGLNVTR
                     VLAEAGQSVVATGFIGGKLGDFVIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTEI
                     LEAGPYIDMDEAEGFLNHMSIIAKQFDVLTFSGSLPKGLAAHYYQDLITMARVYGSKV
                     VLDCSGAPLKAVLAGKDKPTVIKPNLEELEDLIGQPVTLDEERLISLLSQPLFEGIEW
                     IIVSLGAQGAFAKHHNRFYRVTIPKIEVVNPVGSGDATVAGIAWALAEGDDDETLLKK
                     ANVLGMLNAQETRTGHVNMAHFDELFDRIQVEEV"
     gene            complement(17432..17947)
                     /gene="lacB"
                     /locus_tag="TV193_000900"
     CDS             complement(17432..17947)
                     /gene="lacB"
                     /locus_tag="TV193_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEL1513113.1"
                     /translation="MKIAIGCDHIVTDEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPI
                     FGKRVGEAVANGLADLGVCICGTGVGITNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKADYKETEENKKLIAKIAHLESHNANQEDPDFFTEF
                     LDKWDRGDYHD"
     gene            complement(17963..18388)
                     /gene="lacA"
                     /locus_tag="TV193_000901"
     CDS             complement(17963..18388)
                     /gene="lacA"
                     /locus_tag="TV193_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEL1513114.1"
                     /translation="MTIILGADAHGNDLKEAIKGFLQQEGFDVTDVTAIADDFVDNTL
                     AVARALKADEESLGIMIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNARMIT
                     MGAEIVGQELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA"
     gene            18524..19306
                     /locus_tag="TV193_000902"
     CDS             18524..19306
                     /locus_tag="TV193_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1513115.1"
                     /translation="MLKRERLLTIMEKVNANGFITVTDIMESLRVSDMTARRNLDELA
                     RAGKLVRIRGGAQSISMPQKLERSNTEKLTVQIEAKKEIARYASQLINDGETIFIGPG
                     TTLECLAEALINRHIRIITNSLPVFTILNKSKTVDLILIGGEYRAITGAFVGSLASQT
                     ILSLKFAKAFISCNGIYKNDIATYSENEGVIQRLACDNAIEKYLLADNQKFNAYDFYS
                     FYHLDNIDAIITDSKISDSVKERYRQFAKLLIARPADNQVSS"
     gene            complement(19722..20273)
                     /locus_tag="TV193_000903"
     CDS             complement(19722..20273)
                     /locus_tag="TV193_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1513116.1"
                     /translation="MSVTSSMLTLILCMTILWLIGVRNKLERYRIVIEESKRNVDIAL
                     EKRYDTISEMLKIAKSYAKHEEKVFTELVKLRQGLSLEETNDVMRTQEQALNEVFAVG
                     EAYPEMRSSEQFLSLQNEIAKENAALAAAKRIVNSNISLFNQAVVAFPVSIVASLINI
                     KQMTFLDIDLDHKKSLDQLDYTI"
     gene            complement(20286..21236)
                     /locus_tag="TV193_000904"
     CDS             complement(20286..21236)
                     /locus_tag="TV193_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3137 domain-containing protein"
                     /protein_id="HEL1513117.1"
                     /translation="MNENTKRLTDPIVLEKSRAIEASPEHHQKLEQIKSEMSGNARKN
                     NLGWLAMVIGAIILYGMVDRSLALFLIIFVGGLVWPRLKTFKTANELSYVDHFLLPVL
                     QEALPDVKIDYYSGIELSLLKLATPSSRWYDSNCHIIFGDDMQTEFCNLYAYHEENED
                     DNWHRVTDFNGQVLLAKYHTAIKGYIRIVPTQKGFLGREKVHSGYKAKLKGEVQLEME
                     DIRFNETYNVYCTDELSARMLLNPYMLAVLDEWREEMPVAVYMNGDTVVVSFYSGQQL
                     LKTPSSRGAIEKLSLSSEYENIQDKLVKMYRLLDTLNHQL"
BASE COUNT         6089 a         5196 c         4178 g         5886 t
ORIGIN      
        1 cattaaaata ggtagagata ttattatctc tacctaaact gtattgatga gacagatggc
       61 tagtacctca caattaacca tttctaaaaa taatgactct tttgtcgaaa gacctaatga
      121 ttaaagctat ttgtctttgt ttatcttttt ctcattagta acattaaatc atggcaaaat
      181 atttatattc atttaataat caagattccg gatcatcaag tgaccgtcca tgcagacctt
      241 tttcgcgctg cacctgtctt aatttctcag gagtaacatc gtttccgtct tcatcaacaa
      301 tcttaatgcc ttcaatgtga tggcgcactg agcggcgata gccctcaatg tattcctcac
      361 gcagcttggc ctgctctacc ttttcaggac cagtcaagcc aactgttttt ttcttttttg
      421 caagctcgtt aatacgagcg atttttttag gatccataaa tcacatataa gggctgcacc
      481 aaaagcagtg agcagctgat gaggcttgat gatgggctag acagcctctt taggaccgtt
      541 actaggacct ttcaagtcct ttttcaccag ctgtgccagc aagggctgcc tgcaaatggg
      601 gctgcctcta atcctttctc tttcgtttgt gacatagagt actgcactct ttttgtctat
      661 atctaaggct gtgccagcag ctgcttagcc ttatgcttct gccaagaagg ctgtagcaag
      721 cttcttgtga aaagctaaaa tccatgctca ctttactaac agtgttcctg atgcttttat
      781 tgaccactga ccagcacagc tattgctagc aaagctagcc caagacgata tctcgtagta
      841 agcaagagga ctgatttgac taagtatcaa ttgcttgata agtcttgagt gcttagggaa
      901 ggacttatcc caaggcaggt aatcagtcac ctatatcatc tagggaatac gaacagctaa
      961 cacagggcga tgtgcttaat cttacacagc gaattattta gtatttaatc ggtcaaaggc
     1021 cgcaatggtc tctacctttt taaccagctc tgctaacagc gctaaacggt tacgtctaat
     1081 agcttcgtcc tctgtcatga ccatcgtatg gtcaaaaaag tcatcaataa ctggactaag
     1141 ggcaaagacc tgagctagct gttctttggc tgatccagat agcactagtg aatcaacagc
     1201 ctgtgccaaa gccctttcgt agtcattttc aaagaggcta gcatcaatca gcacagcgtc
     1261 aactgccttt ttcgctagat taaagacgcg agacagcgac tcgacagcag gcttgtaggt
     1321 gtctagctgg cttgccgcag ccagagcctc cgctcttgct aacagttctg gtacaacaaa
     1381 gcttgagcta gccagaactg cttcacgtat atcctttgga atggctgagc ccatcatttt
     1441 atccacacgt gcacaaataa agtccagcac ctcagcctta tgctgatagg tcaagctatc
     1501 aaatgacagc tcatataggc tatcaatcag cttatccata ggaatgctcc agccgaaatg
     1561 ctcaagaatt cggacgatcc cctgagttgc acgacgtagg gcataagggt catttgagcc
     1621 tgacggtatc aaaccaacag agaaaaagga cagcagggtg tctagcttat cagcaagagc
     1681 aaggacagca ccaacctttg tttcaggcag ctctccttct gccgaatttg gcaaataatg
     1741 ctcacgaatt gctgttgcga cagcagcagc ttcgccagtt aaaagggcgt atttctcccc
     1801 cataatgccc tgcaactcat caaattcccc aaccatacca gttagaaggt caaatttata
     1861 aatctgggca gcacgagcga cagcactttt ttctgcttct gagagcccag cctggtcagc
     1921 aagaaaggct gcaataacct tggtccgctc catatgctca gccacagagc ctatcttttc
     1981 atggaaggtc acatgagcta gcttagcaac caaatcttca atagatagct tttgatcctc
     2041 acgccagaaa aattctccat cttcaagacg agcaacaagc accttttcat tgcccttaat
     2101 cacattttga agatgcttag cattaccgtt acgaacagaa ataaaattcg gcattagctt
     2161 gccagcctga tcacgcacga caaaataacg ctgatggttc ttcattgagg ttactagaac
     2221 ctcttctggg atttccaggt acttgggatc aaaacttccc atgaaggcag ttgggtattc
     2281 tactaggttg agcacctcat ttaagaggtc ctcatcaata tccacctgaa ccttttgctc
     2341 tgcttcgatg gctctgattt gtgctatgat catctcttga cgctccttag cagaggcaat
     2401 gacaaattgg ctgcgcaggt cagcctcata ggaatcagca cttgtaatgc tagtctcttc
     2461 tccaaggaag cgatgtccgc gactgatacg tcccgaatga atgtctaaaa agtcaagctc
     2521 caaaggctca tcatctaaca gtacaatcaa gctatgcacc ggacgaatat agtcaaagct
     2581 attgttagcc cagtgcatgc tgactgggaa ggtcaaggaa gcaagaacct ctggcaccgc
     2641 tgctaagacg tccttagcct gcttgcccgc ttcatgcttg gtgacataaa cgtattcctc
     2701 acctttgacc tctcggaatt cgatgtcatc aacagtcaag ccctttccac gaacaaagcc
     2761 ctgagcggct tttgaaaatt gaccatctgc gtcaagagca atttttttag agggtccctt
     2821 aaaatcctct gtcagatcag tctgctgatc agctaagccc agcacacgca ctgctaaacg
     2881 acggggcgtt gaaaagcctt cgattgcgtc atagctaagc cgattggcct taagaaaatc
     2941 agccatacgt tcaacaagct gcttttcact aggtgtgaca acgtaggcag gaagctcttc
     3001 aagaccaagt tctacaagta aatcttttgt catcattaaa atcctatggg catcaaatct
     3061 aaaagagaag accaaaccga tcctagcatg ccttgggcaa gcttggacga tcctttgtct
     3121 acaagatttg tcccatcttt ctttcctttc ttcaagttat ggggtaggtt taggagacca
     3181 aatcactagc tcctaatcct gcaagcctgc taataagctg cctgttagac aagatcactt
     3241 agcagaaaga ctgagcttaa caggactagt catcaggcct ttaagtctca tcgcttttaa
     3301 aaagcaccta ccagataggt aagctgctag cagcaactag agcttacaag atcatacaag
     3361 ctgcattgac tacaaggaac tagtttagat ccagctgctt agtcctctgc cagcaaggct
     3421 actcggctag catcatccaa caatgggaag ccaagctttt tacgctctgc aacaaaggtt
     3481 ttagcaacgc tacgagctaa atgacgaatc cgagcaatat agccagcacg ctctgtcaca
     3541 gagactgcac cacgagcgtc aagcaggtta aaggtatgag agcatttcaa gacatagtca
     3601 taggctgggt ggacaagccc ttgtgctaaa gcacgctctg cttctttttc aaatatctca
     3661 aagttttcaa gcagcatgtc ctgattggat acctcaaagg aatacttgga atgctcatat
     3721 tctggctgaa gaaaaatctc gccgtactta acaccaggtg cccattcgat atcatagacc
     3781 gaatccacct cttgaatgta tgaggccaag cgctctaagc cataggtgac ctctgctgtc
     3841 actggtgatg ttgctaggcc tcccacctgc tggaagtagg taaattgtgt aatctccata
     3901 ccatcaagcc agacctccca gccaagtcca gctgagccgg ttgaaggatt ttcccagttg
     3961 tcctcaacaa atcgaatatc atgctccaat ggatcaatgc caagtctttc aagagattgc
     4021 aggtaaagct cctgaatatt acttggagaa ggcttcatca ccacttgaaa ttgatggtgc
     4081 tgatacagac gattgggatt ttcgccgtat cggccgtcag caggacgacg agatggctcc
     4141 acataggcag cattccaagg ctctggacca atagcgcgaa ggaaggtata aggactcatg
     4201 gttcccgctc ctttttcatt gtcataggct tgcattagca tacaaccttg atcattccaa
     4261 tattgctgta gcgtcaaaat aatctcttga aaggtaagtt tgttactcat gatttcctct
     4321 ttctattttt tatgtcttgt cgcaggcgct aaccaagagc tggctatggc ttgactgctg
     4381 gttggctctt aaacagcttt tcaaagagaa aaaccgcgcc tatagccacc tacacctaaa
     4441 ggcatagggg cgtcaaaacg cggttccacc ctaatttatt acttcatttg atcttgttga
     4501 taaacagatg tcaagcaagc tacaaacacc tgagcctact ctttagagaa agcgccaacc
     4561 agcagtacca tcactcggct ctcaccagcc ccgagctcgc tttagatcag aaacctgcta
     4621 ttttctttcc tattggttag tttatcacaa aatcctatga ttgtctaatc aactattatg
     4681 attttggacg agttccgttt ggaataataa cctcagacaa gagcctattt tcttcacgaa
     4741 tgcgcagata aatcacaata atatagcaag ggaaaagcag cattgccgta atctgagcat
     4801 ggcaaagcaa agcaatacca accagctctg gagcaatgtt taaaaagtaa ttggggtgct
     4861 taacagtctt aaagagccaa tgatcgacat atttatggtc ctttgccagc atcagcttca
     4921 ctgtccaaat atctcccaag atccgagtta cctcatatag cacagctatc gaaaaaatca
     4981 tcagcagcaa gccaagaaag ctaatgccat caaacttaat ctgcttgagc aatgcctctg
     5041 tcacagcaaa gacataaatc atgatatgca gcagggtcaa aaacttagtg ttttgcgcac
     5101 caaattcctt gcccccatta gccaggatag ccttctcgtt tttgatcgat ttttttaaga
     5161 atactaaacg aatagcaaac atcaagagca tcaataacag gataatcaaa gtaagactcc
     5221 tttattctag tttaatctgt ttctttcacg aaacactaat taagattata gctaagttac
     5281 acagccttgt caaaccgttt tcaaaaaaaa gatgtctttc tttgatctct aaaaacaaga
     5341 ggtcgtcaca cagcaccatc aagagacctc atcaaagctt taaggtcgta ccaaatcacc
     5401 atcaaaagac agctcctaga ctcagtcaat tcacgagcag caagcagcac ccaagaggca
     5461 ttttgcaggc ctgacctact tcgcctgtcg taaacacaaa tcctcaatat ggtaaatagc
     5521 gtcacattgc gctgcaacct catcgctgtg tgttgccatt aagacaatca tatcctcagt
     5581 ctgacaagct ctgatggctt gtaagacctc ctgctcagcc tcaatatcca gggcgcctgt
     5641 tggctcatct gccaataaca gctgcggtgt tttgaccaaa gcacgagcaa ggaccactaa
     5701 tgtagctcac ttaatccctg cagctcttgc taaaagtcct tggtatcagg atctgggata
     5761 gctgacatac ccggcaggca acgaatgcgc tctgaatcct ctggactaat ctcacaatca
     5821 aaaatagcca tattttctac tatgcgttcc ttgtgcaccg acttaggtag aggaataaag
     5881 ccctcagcaa tagaccaagc aagggctagc tgagccactg tcttgttgta ctttttagcc
     5941 aatgcctgca tggtatcatc ggcaaatatc tctccttgtc ctaatggacc ccaggcctct
     6001 agcaaaatgt gatgcctgcg gcaataatca accgtctctt tttgatagca gccaggcgcc
     6061 aagcgaatct gattgactgc tggtgtaatg gttgctgtct gtttaagagc ctccagatgg
     6121 tgaaccataa agttgctgac accaatcgag cgaaccaagc ctgcttcaac agcctcctcc
     6181 atataagacc aagctgctgc attggctgct tgccagcaat ccctaagagc cttaggattt
     6241 ggccaatgaa tcagataaag gtctacatac tctagtccaa ggcgctcaag agaggctgct
     6301 aaggctgcct tagcgccatc atagctatga gcatcattcc agagcttagt ggtaataaag
     6361 agttcttcac gaggaacgcc cgaatcccga atggcctgtc caacactttt ttcattgtga
     6421 taaatggcag ctgtgtcaat atgacgatag cctgccttaa tcgctgctag ggtggattgg
     6481 taggcctcct caccatcagc agccttaaag gtcccaaagc caagcactgg aatagcaaga
     6541 ccattagcca ttgttactgt tttaatcata tctaaaacct cctttttcat tgtagcacaa
     6601 tgataagcaa agcaaaaaga attgagctga tcaccagccc aattcctttg ctgtattaag
     6661 cctcaaaggc cttttgacca tttaggtagg ttgctactaa ttctaagtcc ttatcaagaa
     6721 caataaagtc agcagcatga cctgccttga tttggccaca gacatcttca ataccaaccg
     6781 aagcagctgg gacgtaagag gacatgtgaa ttgcttctgc tggacttgca attccccagg
     6841 caacaacatt tttaatgccg tcctttaatt ttaagataga gcctgctaga ttaccactat
     6901 ccttcaagcg agctgtgcca ttttccacaa taaccggaaa ctctccaagc atgtaatcac
     6961 catctggtga accgcctgca cgcatacagt ccgtaatcaa agccacatgc tcatgaccct
     7021 tttgctgcat caaaatatcg caagcaacag gtgagacatg atgaccatcg cagatcagct
     7081 ctgcaaccgt tccaggaata ttataaacag ccccaaccat accaggctca cgatgagtca
     7141 agccacgcat cccattgtag gcatgaaccc aaacactagc tcctgctgct actgcctttt
     7201 tagcctcagt ataggtacca tttgagtgac ctaaagctac tgtgacaccc tgcttggtca
     7261 cctcagagac aaatgcttct acgccatcac gctcaggagc caaagctatt tttttgatca
     7321 agcccttagc tgctttttgc caagctgcaa attcgtctaa gcgaggattt ttcatatata
     7381 tcgggttttg ggctcccttg tattcctcag tgaagtaagg cccttcaaaa taaatcccct
     7441 gaatctttgc tcctttgacc tgatcggcaa cagaagcaac ggttgcagac acctgctcta
     7501 gatgctcaaa ggttgacgtt agggtagtcg gtaagaagga ggtcactcct gttgataaga
     7561 gaccctcact gatggcatgg agaccttctg ctgaattatc catcacatca gcaccagcat
     7621 agccatgaat atgagtatct acaagtcctg gtgctatttg atagcctgta taatcaataa
     7681 cctctgcctg atcatcaaca gtagccgtcc aataaccaaa tgtgccatta tttagctcca
     7741 aatagcctgc tggctttacc tcgttggggt aataaaagca atctgcttta atatagcttg
     7801 tcatcttttt tcctcccttt ttcgtttatt atacgcctta attcttattt tgtaaatggt
     7861 atataccagt ccttctgtta aaaagaaaaa cctgaatact atttcaagtt ttccctttta
     7921 ttagagctgt cctgaaagta ctttctcagc tagatttagg gcgtggtcag tgatacgtgt
     7981 gtaatgagat ataatgtcaa taaaattaat ccctgcctgt gctgtgcatt cgccacgatt
     8041 gaggcgttcg atgtgtgttt tacgcaattg acgctctttt tgctcaatcg tcctatgacg
     8101 ctcaacaata gactgggcta gagccttgtc actatccaca atcgccctaa tcgcatctaa
     8161 agttaaacag tgggtcaggt gatacatttc tgttaattca ccacgtgcag ctgctgaaaa
     8221 gccaatctgc tttgctgtaa tcccctcaat gagagtcgct aacgactcag agtggtcacc
     8281 aattcgctcc aaatcacgag acgaatccaa cagacctgct aaaacctcat tttcactagg
     8341 actaagggct tcattggaaa tatcaacgag gtaagtggtg agctcctcat caatcgtatt
     8401 gaccgccttc tcatatcgcc tcaccttttc gccaaacttg tcttctgctg tcataatgta
     8461 gctataagac gcctcaaaag cctgaatagc ataggaagcc agatgtacca attccttgtg
     8521 ggcatttccc aaggcaatag aaggagcctg agtgattagt aaacggtcca aatacaaggc
     8581 ttcatatttg acgatttcgt cttcacctgg aattaaggtg gtcacaagct ttgccagagt
     8641 gttgataaaa ggaagcagca acagggtatt tgtgatgtta aaggtcccat gtgaaaaggc
     8701 aatggtcatc tcaggtgaca gggccaaaac agactgaagc catagcataa aggaggtaaa
     8761 tggcatcagt aaaatcataa agatgaccgt cccaataaca ttaaaaagaa tatgagcagc
     8821 agcaacacgc ttagctgcaa tattagagcc aatagctgcc aaaaccgctg tgatacaggt
     8881 accaatgtta gagccaagca aaataggaat cgcaccctgc agggtcaata ggccacccga
     8941 aaaaagcccc tgtaaaatac caataatggc cgccgaggat tgaatcagca tggtcaatgc
     9001 tgtcccgata aaaacaccct gaaagggctt gtctccaagc gtcgctaggt aatgctgaaa
     9061 ggctgagact gattttaaag gatccatcgc atcacccatg aggttgagag aaaagaaaat
     9121 tcctcctaca ccaaaaatga tacgacctag gttattgagt tttttatttg acgtgaaaaa
     9181 gagacaggct gctccaataa aaatcatggg cagggcgtaa tctcccagct taaaaccaat
     9241 caaaaaggag gtcactgttg ttccaatgtt ggcccccatg acaataccaa tcgcctgctg
     9301 tagggttaaa aggcctgcag atactaggcc aactgtaatc accgtcacac ccgagctaga
     9361 ctgaatcaaa gcagacatag ctattccaac caagatacca aagaaggggt tgcttgtgta
     9421 cttgtcaatg taatacctaa gcttatcacc tgcggcctgc tgcaagtcgt ctcccatgta
     9481 tttgatactg aaaagaaaaa gacctaagcc ctgtactgcc ccccaaaaaa tgaaacgcaa
     9541 tgtcttgcca atttaccgac acaatattgt cctcactcgc ttatttattc tcttctattt
     9601 taatgtattt attcagttat cacaagggtt ttttaatcct tttaaatagt gctcatttag
     9661 aacctatttt agagccctag tcctcttttc attttcctat attcagggta taatagtgct
     9721 actcaagcga caatgatttc aaaggagata ccatgagaaa accgacaaaa gagacccact
     9781 acctcatcat tagcttgctt actattgcca ttgcaggagg ggcctacctt atttttagta
     9841 gcctctctcc aaagccagct accattacca cccaatctaa gggctatgag ctgttaacta
     9901 aggctcaagc attagtcaag gaggccgaag acaacccaac taaagaagct atcgcaaagg
     9961 ctcaaaaagc aattaatcag ctaaaaaaga cccagtctaa ggaggaatta caggctcgac
    10021 taacagctat cagcttaaag cacaatcaag aagacgttgc tatcaaggtc ctaaaggcag
    10081 ccgaggacaa tccaagccct gaacttaagg aggctgcaca aaaagccatt agtaagctct
    10141 ctgatgaggc taaaaaagct gccttacagg ctagacttga cgctattgga ctttcaaagc
    10201 ctagcactgc acagcctgag actgcaacac cagcagcaga aaaaaatata gcaccagctc
    10261 ctgcggctcc acaaataaag cataccacac cgtcttctgg gggaacgacg ccagcaccga
    10321 accctaaacc tagtcctaag ccgaatcctc agcctagtcc tagtccagct ccagagaacc
    10381 cagagccaac gcctagtcct aaccctcagc caaatcctca accagaaacc aacacaccta
    10441 gccctcagcc acctgcaaca gagcaaagtg aaaacactgc tccagcagga caaaactaag
    10501 aaagggcagc cagagctgct gtagcttagt tacacttctt agtacaggca ataagggctt
    10561 agctactgaa ataatgctaa acttacgact aataagctct ctgataaaaa gaggctttag
    10621 gtgattaaaa acagctggtt ctaaaaggat tccagctgtt tttgtgcttc ttaattgatt
    10681 ttgaggtagg aagagaaggg aggcttaatc aagtcgataa gtaatcccat atcctctcct
    10741 aactctctat cagcttggct atgattatag agcggctcac ccttacgcgc tttggtgatt
    10801 cgtcatggat attctgactg gcttgaccat ttgagttttt tcctcagtgt cactccctaa
    10861 gacttttaag ggactgacga ggtgattagc atgcacaaca aaaagccctt aaacacacct
    10921 ttaaggacct tgtattcagc ttaatgcctc tatagtatca gggatatttg ttaaggcagc
    10981 tctcagctaa agacttgtga taaagaccta tgcctatccg accactagct agagtcaagc
    11041 tgtgcatagc tcagcctcta tgactaacag aaaccagagg cagcgttaga tcactttgct
    11101 tagcttaaac ctcatagccc atgagaagcc cttcagcttc tgcatagaag ctgcataggc
    11161 ctgaggctgg gctggtttga atctctgctt ctgggtaaat cgctctaatt ttttccgcaa
    11221 tttgctcaca gatcttaggg tttttggcgt gggagataaa gactcggcct cctttatagc
    11281 ctgccttttg aatctcttct aaaacagctg acactgcctt tttttgacct ctggcctttt
    11341 gaagcagctc aagcgtgcct tccttacttg cctgtcctac cattctgatg tttaataagc
    11401 caatcacctt accaatgagc ttattcagac ggccattttt aaccagatta tcaaccttgg
    11461 ccaacacaaa aacaagcctg gttttttcct gataagctgt aattttctca acaacctcat
    11521 caaaagaaag cccctgattg atcaaccgct ctagctctaa cacaatcaaa tccatctcac
    11581 cacctgctga caaagagtca atcacatgga tattggcatt cggattttcc tcaagcaagt
    11641 cattttgagc caatctagca ctattgtgac tgcctgagag cgtaccggta atggtaatgg
    11701 caatgacgtt atctgctccc ctgtaggctt gtaaaaaagc atcaggactt gggcagcttg
    11761 aggttgctgg cttagaggac tgatacatag tctccatcat ttgatcaata tctagaccat
    11821 catcatctct aaaaatatct gaaccaatct gtagggttag cggcacacgc tcaaagcgca
    11881 ggtgattgga ttggcttttt agggctctaa tatcgcagcc tgaatccgat acaattttcc
    11941 aggtcattcg ttttcctctt ttccttcata gtctgttttg gttgacaaag taagcatttt
    12001 cccataaaat tatatcatca ctagctagac ttttgctagc taaacgacat cagatgtaac
    12061 acttgaaagg tatttgtaat ggctggtaaa ccaatttcta aacagtccct tcaaaattta
    12121 gcccactgca atcaggaatc cagacggtta acacgagaag ctattgaaat tgctctgctt
    12181 agcttactag aaaagaagcc cttaggacac attaccattt cagaattggt agctagagct
    12241 ggggtttcaa gaaatgcttt ttaccgcaat tacagctcaa aggaggatat tcttgagtgt
    12301 ctgttgactt ctgttatcag acgtatcttt cgtggactga aggcctttga tctaaagaca
    12361 caggcctatc aggcatggct ttatctgttt acagaggcca aaaaagaagc gacgctactt
    12421 agtattatct ttaaccatca cctgcagcag ctcttgacgc agatggttac caagcgtttg
    12481 agagcctacc aaaagtggca ggaaaaaaag ctgtctcact acgcactgct cttttggagc
    12541 aacgctattg tctcagtcct ttccaattgg atttctgatg atatggttgt tcctgctgag
    12601 gagatggctg ctatggggct gcccttatta gcctagttgt ctctagatca cctatagctc
    12661 ctagacaact tcccaagaaa ccaagcttgc agcatcagac aggacgcttg gctggcttga
    12721 cttaagcact ggcactgcct accaagatat gtactagccc tactacaggc aaggtgtgac
    12781 ttgtcgctcg ctgttgtgca gaggcttaaa ggctcttaca tttagctgga caataaaaaa
    12841 agactgaaga ggctggctgg attagcctgc tcttcaatcc agaacctcct ttgttggagg
    12901 ttttttcgtg ttttattttt cagtcgatct cacacaccta ggcttgtggt gttccaagac
    12961 agctcagctc tagtcaacac ctctaaaact gagcttatca tctctagctt ttggaggcct
    13021 tttctgacgg gctggtttga ctgtgcttaa gagccctttg tcaatgcaaa ttgattaatg
    13081 gcatgggcca cgcctgcttg atcattggag aggcttacct tgtcagcgac ctttttaatt
    13141 gcctcatcag cgtttcccat agcgacacct aagccagcat aggctaacat ttcaagatca
    13201 tttgctgcat ctccaattgc catcacttgg tctgggcgca gcttcagatc agcggttaat
    13261 tccttcaggg cagaggcctt ggtcacacac tccggcatta cctctaggat tgtttcttga
    13321 ctgcgaacca cactaaagct tgcgctgagt ttttctctaa caagagcctc aaaagtatct
    13381 agggcagcct tttctcccat gtacatggcc tgaaatatga tttgactgct gttggataac
    13441 tgagataggt tagtagcctt tacctttgta aaaaccaaat caccatcagc ctgaaccata
    13501 tctggaacct tgctatctat cacaagataa tcacgctctc cagtcagggt gaggtaaata
    13561 tctgaaaagg gctgagacag ctgataaagg tgctcaatag ctgaaaaggt caggctttga
    13621 taatgtagca gctcccagct tgggctccta taggtgctac agccattgtt taaaataagg
    13681 tactcctcct tatcactcaa gcctaattgc tcaaaatacg gccttgtccc agactggggg
    13741 cggcctgtgc agagaacaac ttttatcccc tcttgtgcag ctgcttggat agccttaata
    13801 ttctcttttg gaatgtgctt tttgctatca agcagagtac cgtctaaatc aattgctata
    13861 agctgaatca tcgtctcagt cctctttcca ttttatctta ggtaggtgcc attgtctttt
    13921 gttgccaatc atacgcatga ctgtcaataa aacaaccagc aagtagcatt caacatttga
    13981 agtggccagc ttaaaataaa gcacaagtgc tgctataata gaccagccag cataaatctc
    14041 acttctaaga acagttggct tacggcctgc caggacatct ctgaccacac ctccgcctgc
    14101 ccctgtaaga accgctgcta caataacagc gcttaagggc tgggctagtc gaacagcatg
    14161 tagagccccc tgaacactaa aggctgcaag tccgatagca tcagtcagca ccgctgctct
    14221 cacccagccc ttagccacaa gcttaggaaa tagcatgatc agaataatag ctataaaagc
    14281 gcaggcaaat tctggtcttt gtccccacaa ggcttcaata ggcagcccga tcagggtatt
    14341 tctaatagcc ccaccaccaa aggctgtgac aaagcctaga ataaaaatcc ccagaacatc
    14401 aaactcctcc tccatagcga caatagcgcc ggacaaggca aaggctatcg ttccaataat
    14461 gcttaaaagc tcccacatat caattgtcat aactcaccta atgcttccta atcccctatt
    14521 agtctaccat ctttttaatc aaaatataag tcaaaataag agcaaggtcc tcaaaaatcc
    14581 tactgatgac ctgtttttgt ttgcaccaaa gatttagccc ctatataggc taggctccta
    14641 gtagcaggag ttaggagcga tagcttgcca aattcacagc cttgttattt tccatgagaa
    14701 agggctctgc tgatgtcttg gtttgatagg tcttgtattt atggtagagg tattggtagc
    14761 aatcctgttt ttgatcaaag aggatggctt ggtagggctc ttggaaggac aatttctcaa
    14821 caaacagata cttgctctta tactccacta gcactcccac atgaccaata aaaaggtaat
    14881 caccatctag ctgatcgtga atcacaacag caagcatttt ggctgggcca ttaaagctaa
    14941 cagctgagaa atgctcttgc atatgcttgg catgcacctg aatatccttg gtggcttccg
    15001 ttttcactct tgaaaacagc tgcttaaagc gctctgtctc tgcctgtgta aagagctggc
    15061 ttgtggtaat ggcgtcctcg tccataaata aaagcgtatc atcactgctg gtaggcgcaa
    15121 tcgtcatgct atcctttaga agcataaagg tgttgatccg gcaattagtt ccaatgaaat
    15181 tgccttgctt ttgcgaccac aactcatcga ttgctaccac atcatagtca ggctgcttct
    15241 gataggtaaa ggcccctgtc aagcctgttt tgccaactag gctattatat tcttgtacac
    15301 cagccataaa ggcattgaca ttagcttcct tcagctgatg tgatagggca gccctgacct
    15361 cctgctggct ctttgcactg ttcatgttgg ataggaaaag acgtcccttc ttagcctgtg
    15421 gctctttttg ctcctgcttg ggctgatcag actggtgaga agcctggcaa gccccaagag
    15481 ttgccgtagc aaggattagc aaagacatca ttactttttt catcataacc tcctttttaa
    15541 tgagtcattc aagctggtac tctccatcat caccaaatga gattatcagc agctggcagc
    15601 taatacgagg ttgctacaac ccacttgtta tctctttatg tcatgacctc atcgttacca
    15661 gtatagcata aaaaagaaaa gcaccagctc ttgaagcctt gcagcccttg tgccggtgct
    15721 tttcgttagg agattacact gaaatagttt ttgtggtagc tagctgctga taccaataag
    15781 cgcttttttt agggtaacgc ttttgggttt caaaatcaac atagaagagg ccataacgct
    15841 tatcatagcc atttgaccaa gaaaagacgt ccatcaagga ccagataaaa tagcccttaa
    15901 cattagcccc agcaccgata gcgtctgcaa tcacagccaa atgctgcttg atgtaatcaa
    15961 ttctagcgtc atcatcaatc ctgccatcaa tacaggtatc cttgtagcca aggtcatttt
    16021 cagtgatata aatcttttta tagcctggat agtctgcctt gatccgcatg atttgatcgt
    16081 aaagcccctg tggatagatc atccaatccc agtctgtacg cggcacatca acatcaaaca
    16141 cgcgttgacc aacccccttt atctgatatt tggagccgcc tttttctccc ttgccattat
    16201 gaatgatttc ggtctcacca tggctaataa taagccagac ttctcatcac gtaccttagt
    16261 ggctggcagg ccatattcag ggtctagcag gatagaggag gcataggggg ttagctcctc
    16321 tgataccaga gcctttaggg cttcgatttg ccaaggagct ggctctgtgt cttggtgggc
    16381 tgccatcatg cgctttaaag ccccgcgttg atcaaaggcc aaggccgaaa tgattccctt
    16441 acgactgacc ttttctaaat aagctttttt gtttcttgtt aatgtcatct tatacctcct
    16501 ctacttgaat acggtcaaat agctcatcaa aatgtgccat gttaacatga cctgttcttg
    16561 tttcttgcgc atttaacatg cctaaaacat tggctttttt cagaagcgtc tcatcgtcat
    16621 ctccttctgc caaagcccaa gcaatccctg ccacagtagc gtcaccagat ccaacaggat
    16681 tgactacctc aattttagga atggtaacac ggtaaaacct gttatgatgt ttggcaaagg
    16741 ccccttgggc accaagagaa acaataatcc attctatccc ttcaaataaa ggttgactca
    16801 acagagagat taaacgttcc tcatctaatg tgacaggttg gcctatcaaa tcctccaatt
    16861 cttccaaatt gggtttgata acagttggtt tatctttgcc agccagtacc gcttttaaag
    16921 gagcaccaga gcaatctaaa accactttgc tgccatagac tctcgccata gtaatcaagt
    16981 cttgataata gtgagcggcc agacccttag gcagactgcc tgaaaaggtt aagacatcaa
    17041 actgcttagc aataatactc atgtggttca aaaagccttc ggcctcgtcc atatcaatgt
    17101 agggaccagc ttccagaatt tccgtctgca tgccttcatg taaaacagca atacaatttc
    17161 tcgtttcccc tttgattttg aagaattggt tagaaatgcc ctgttcttgt aactgatgaa
    17221 tgacaaagtc acccagtttc ccaccaataa atcctgttgc cacaactgac tgaccagctt
    17281 ctgctaacac tctggtcaca ttcagcccct taccaccggc tgtttttgtc gttctgtcaa
    17341 cacgattaac cgtgtccaaa gtcagacgat ttagaggata ggaaatatca atggatgggt
    17401 ttaaggttac cgttaaaatc atcgcttctc cctaatcgtg gtagtcaccg cgatcccatt
    17461 tgtccaaaaa ctctgtaaag aagtcaggat cttcttggtt agcattatga ctttccaaat
    17521 gggctatctt agcaattaac ttcttattct cttcggtttc cttatagtct gcctttataa
    17581 aggcctcaat aatatcacac atcaaaagct cacctgtgat tttaccacca aagccaatca
    17641 cattggcatt caattcttct ttggcataaa gcgctgttgt catatcccta acaagcgctg
    17701 agcgaatgcc aggaaccttg ttgacagcat tagtgatccc aacaccagtg ccacagatac
    17761 agacaccaag atcagctagg ccattggcga cagcctcacc aacccttttc ccaaaaatcg
    17821 ggtaatgggt gcgggtatgg tcataggtcc cacagtcaat cacttcatag ccctttgatt
    17881 tcaaaaaatc tgaaacagcc attttttcat cagtcacaat atgatcacag ccaatagcaa
    17941 ttttcatgat atcctccctt cgttaagcca ttttattgag catgtcaaca cgaatttgat
    18001 gacggccacc atcatagtga ccagtcacaa aacctttagc aatattctta gccaattctt
    18061 gacccacaat ttctgctccc atggtaatca tgcgggcatt gttatgaccg cgagtcatgt
    18121 aggcagagcg ttcatctgac acttccgcag cgaccatacc tttgattttg gtagcgacca
    18181 taaatggccc tgctccataa gcatcaatca taatgcctag actttcctca tcagccttga
    18241 gcgccctagc aactgctaga gtattgtcaa caaagtcatc agcaatcgcc gtcacatctg
    18301 tcacatcaaa gccttcctgc tgcaaaaagc ctttaatagc ctcttttaga tcatttccat
    18361 gtgcatctgc acctaagata atagtcatag gatctccttt tattgtcatt accgttcaaa
    18421 attgtttatt tttgttttgt tttttattat tttgttgttt attgaaaaaa gagactgttt
    18481 atgctattat gagttaacaa tacaccagag aaagtagcgg cctatgctta agcgtgaaag
    18541 attgttaaca attatggaaa aggtaaacgc caacggcttt atcactgtca ctgatattat
    18601 ggaaagccta agggtttcag atatgacagc caggcgaaat ttagatgagc tagcaagggc
    18661 tggaaaatta gtacgtattc gtggcggtgc ccagagcatt tctatgcctc aaaagctgga
    18721 gcgttcaaac actgaaaagc taaccgtaca aattgaagct aaaaaagaga ttgccagata
    18781 cgctagtcag ctcattaatg atggtgagac catttttata ggccctggga caacactaga
    18841 atgcttggct gaggctctaa tcaaccgtca catccgtatt attaccaaca gtctgcctgt
    18901 ttttacgatt cttaataaaa gtaaaactgt tgatctcatt cttatcggtg gtgagtaccg
    18961 agccatcaca ggagcctttg ttggcagcct tgcaagccag accatcttat ccttgaagtt
    19021 tgccaaggcc ttcatcagct gcaacggtat ttataaaaat gacattgcca cctacagtga
    19081 aaacgaaggg gttattcagc gcctagcctg tgacaatgcc atcgaaaaat acctgctcgc
    19141 tgacaaccaa aagtttaacg cctatgactt ttacagcttt tatcaccttg acaatatcga
    19201 cgccattatc actgactcca agattagtga cagcgttaag gagcgttacc gccaatttgc
    19261 caagctctta atcgcaaggc cagctgacaa tcaggtcagc agctagacag cctgcctctc
    19321 tatctgtttc caccctgagt ccagcaggta aacaaagcta tcaaacgaaa tagcatcata
    19381 aaagcgcatg aagccactaa tattgcaatg gggcttcatg ccttttttaa cctatcacac
    19441 gttaagcaaa gcaaaaagag gctaggacaa aaatccttcc tcttttaaaa tcgtcaaact
    19501 atagagttga ttggagggct cttagccctc atttttcaag cgatgtggcc tttttaatca
    19561 gctgctcgag ggtggataac ctaatcaaca tcgccaggtc atgacgattg aatggttatt
    19621 ccactctttt tctacgctga gggctgtgaa agggctcata cgacagctta gccgctttct
    19681 aacagctatt tacctacctc acctcttaac gagcagacag cctaaatggt atagtccagc
    19741 tgatcaagac tctttttatg gtcaaggtca atatcaagaa aggtcatctg cttgatattg
    19801 ataaggctgg ctacaattga taccggaaaa gcaaccaccg cttgattgaa gagactaata
    19861 ttactattga caatgcgttt tgctgctgcc aaggctgcat tttccttagc aatctcattt
    19921 tgcaggctca aaaactgctc agaggagcgc atttccggat aagcctctcc tacagcaaaa
    19981 acctcattca aggcctgctc ctgtgtcctc atcacatcat ttgtttcctc caaggaaagc
    20041 ccctgacgca gcttcacgag ttcagtaaag accttttcct catgcttggc ataggactta
    20101 gcgattttta gcatttccga aatggtatca tatctcttct caagagcaat atcgacattt
    20161 cgtttagact cctctataac gattcgatac ctttctaatt tgtttctcac tccaataagc
    20221 catagtatag tcatgcaaag aataagtgtt aacatagatg acgtcactga cataaaaaag
    20281 cctccttaaa gctgatgatt tagtgtatcc aacaagcggt acatcttaac aagcttgtct
    20341 tgaatgtttt catattcgct acttaacgat agcttttcaa tagcccctct agagctaggg
    20401 gttttcaaga gctgttgacc ggaatagaag gacacaacaa cagtatcacc attcatataa
    20461 actgctacag gcatctcctc tctccattca tcaagcactg ccagcatata aggatttaag
    20521 agcattctag cgcttaattc atctgtgcag tacacattgt acgtttcatt aaagcgaatg
    20581 tcctccattt ccagctgcac ctcacccttt agcttagcct tgtagccact atggaccttt
    20641 tctctgccca aaaagccctt ttgagtcggc acaattctaa tataaccctt gatagctgta
    20701 tgatatttag ccagcagcac ctgtccgtta aaatcagtga cccgatgcca gttatcatcc
    20761 tcattttcct catggtaggc ataaagattg caaaattctg tctgcatgtc atctccaaaa
    20821 ataatatggc aattactgtc ataccatctg gaggacggtg ttgcaagctt tagtaaggag
    20881 agctcaatcc ctgaatagta atctatcttg acatctggca gggcctcttg taaaacaggc
    20941 agcaaaaagt gatccacata ggagagctca tttgctgttt tgaatgtttt cagccgcggc
    21001 caaaccaagc cccccacaaa gataatgaga aataaggcaa gagatcggtc aaccatgcca
    21061 tacaagatga ttgcgcctat caccattgcc agccagccca gattattctt tctagcattt
    21121 ccactcatct cgcttttaat ttgctccagc ttttggtgat gctcaggcga agcttctata
    21181 gctctactct tctccaaaac aataggatct gtcaatcgct tagtattttc gttcatctca
    21241 cttactccag atacttctcc atcagcagcg ctcagctgct cttgataaca ccagtcactt
    21301 tatgcttttg cttaacctat aaatgacaat tgcgttacag ctaatttat
//
LOCUS       DARYXS010000030        21124 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.030, whole genome shotgun sequence.
ACCESSION   DARYXS010000030 DARYXS010000000
VERSION     DARYXS010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21124
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.030"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            480..695
                     /locus_tag="TV193_000905"
     CDS             480..695
                     /locus_tag="TV193_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1513118.1"
                     /translation="MAYRLRNRLKELRARDGINQTQMAALAGVSRQTISLIERNEYTP
                     SIIIAMKIAKVFNEPIEQVFSLVEGER"
     gene            692..1468
                     /locus_tag="TV193_000906"
     CDS             692..1468
                     /locus_tag="TV193_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEL1513119.1"
                     /translation="MKAFMTEKDSTLVRILKSLLLGSGIGLVLGGLVGFGLARFNILE
                     NGFPISEEDTITGIKWGMRPLVIVLMLLSIYDIYQVVKEYARYVKLSDDETEELYRYI
                     NLKHAYALGFSAMAMVLNIVVFSLGYRVPIANNASYLGLTFPIYEALMLVVISVLHAY
                     ILKVYTRIRGVKMTLAPTLKELKQNILQQDEAELQANYQMSFEVVLGLSGFILPGIYV
                     ILLLLSMIFQRVELTGLIITASIHLYILVKSFKSAHDFYR"
     gene            complement(1537..2793)
                     /locus_tag="TV193_000907"
     CDS             complement(1537..2793)
                     /locus_tag="TV193_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL1513120.1"
                     /translation="MITRLITFLTWTGQLVVAGVIAGVVAYVLTQAIHFIQAISFGYQ
                     SGSFSTMIATVAPERRFLSLLLAGAIAGLGWQLLAKKAKPIQPIQQTLSQQKDFSPWT
                     QFCHGWLQLITVSMGAPVGREGASREVAVALTAACNKAINASAAEQGLLLACASGAAL
                     GAVYQAPLATIVFIMEAIVKKCSVKHIYAAAITAFTAVQSVLVLSGHQDIQYLILPQA
                     WQLTTVLWAIIASPILAFLAFCYQQLLQNAPKAKPKSRWFIPRVLGAFGFSACLSLYF
                     PEILGNGKAGLLLLLHHDVSLSYTASLLLSKAAAVYAVFASGAKGGKIAPSMMLGGAS
                     GLLLASLSNQLGYLSVPLPLAIVIGATLFLGIINQIPLTAPLFLIEITGQPLISLVPL
                     AIVGLTSYLSQQLFQKSLFFNKHKKL"
     gene            complement(2879..3838)
                     /gene="nrdF"
                     /locus_tag="TV193_000908"
     CDS             complement(2879..3838)
                     /gene="nrdF"
                     /locus_tag="TV193_000908"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1513121.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RRLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKDVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEDIFEWTNNNVFLQNKAKIINDIYENGSALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSESEQESLR
                     DWMYDLLYQLYENEEQYTKTLYDEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL"
     gene            complement(3983..6142)
                     /gene="nrdE"
                     /locus_tag="TV193_000909"
     CDS             complement(3983..6142)
                     /gene="nrdE"
                     /locus_tag="TV193_000909"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1513122.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVDGSIPLHKDKEALEAFFTENVI
                     PNTMSFSSINEKIAYLVDNDYIESAFIQNYSPEFISHLAKSIQAEGFRFKSFMAAYKF
                     YQQYALKTNDGNFYLESIEDRVMFNALYFADGDETLAKDLAIEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLLQVTDDMNAIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLSVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARHNADMYLFSPYSVEREYGLPFNYIDITSMYDELVANPNI
                     TKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVKMGTDISCNLGSTNILNMMTSPDFGRSIRAMTRALTFVTDSSNIEAVPT
                     VKNGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLMNYWTLVESNQIAR
                     ERQTTFVGFEKSTYASGAYFDQYITGECVPKSELVKSLFKDHFIPQAADWKALRQAIM
                     TDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATKHVDQGLSLTLFLRSELPKELYEWKTESKQTTRDLS
                     ILRHYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(6163..6381)
                     /gene="nrdH"
                     /locus_tag="TV193_000910"
     CDS             complement(6163..6381)
                     /gene="nrdH"
                     /locus_tag="TV193_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEL1513123.1"
                     /translation="MITVYSKHNCMQCKMTKKFLEQHGAAFQEINIDEHPEKVDYVKS
                     LGFTAAPVIETEQIVFSGFQPAKLKDII"
     gene            6803..7066
                     /locus_tag="TV193_000911"
     CDS             6803..7066
                     /locus_tag="TV193_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEL1513124.1"
                     /translation="MASKDFHIVAETGIHARPATLLIQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTITAEGADADDAIAAIEETMTKEGLA"
     gene            7071..8804
                     /gene="ptsP"
                     /locus_tag="TV193_000912"
     CDS             7071..8804
                     /gene="ptsP"
                     /locus_tag="TV193_000912"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEL1513125.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DVALQASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATIDEEAIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     LIAVNGITGEVIIDPSEEQILAFKEAGEAYAKQKAEWALLKDAQTVTADGKYFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKVVFEEEKASLLSEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMAEYAHRALTECSTAEEV
                     LELAKEYITEA"
     gene            9006..10433
                     /locus_tag="TV193_000913"
     CDS             9006..10433
                     /locus_tag="TV193_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1513126.1"
                     /translation="MAKQYKNLVNGEWKLSENEIKIYAPATGEELGSVPAMSREEVDQ
                     VYASARAALADWRALSYVERTAYLHKAADILVRDAEKIGAVLSKEVAKGYKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPINLA
                     GSKIAPALIAGNVVVLKPPTQGSISGLLLAEVFAEAGLPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGERIGKLAGMRPIMLELGGKDSAIVLEDADIALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMESVADQLVAEIKGLVEKLLIGMPEDNADITPLIDTKAADFV
                     EGLVNDAADKGAQALTEIKRDGNLICPILFDRVTTDMRLAWEEPFGPVLPVIRVSSVE
                     EAISISNQSEYGLQASIFTTNFPQAFAIAEKLEVGTVHINNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTSLKSVVFDIQ"
     gene            11086..12300
                     /locus_tag="TV193_000914"
     CDS             11086..12300
                     /locus_tag="TV193_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1513127.1"
                     /translation="MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLA
                     TVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAAT
                     GAKNWITIGSTTLFQPSEFMKISYILAMSWLTVWFKRKQERSRFLDDWKLLGLYLVLT
                     LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALVLVFLLVSAFFFVFLLP
                     EGKEFLLKMGMDTYQLNRISAWLTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLEL
                     SVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFASNNLFYTYISTGFIM
                     MILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQ
                     SEHELSRSSRYV"
     gene            12396..12965
                     /locus_tag="TV193_000915"
     CDS             12396..12965
                     /locus_tag="TV193_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1513128.1"
                     /translation="MKVMNYHDYIWDLGGTLLDNYEISTQAFIETLHFFKLSASHDAV
                     YQRLKKSTATAIQVFAPNEPQFLQYYKANEAKKLANPIWCLGAKDILKRIVASGSRNF
                     LISHRDHQVNDLLEQAGLLGYFTEVVTASNGFARKPNPESLLYLKEKYLISKGLVIGD
                     RRLDIEAGQAAGFDTLLVDGRKNLLEIVD"
     gene            12966..14918
                     /gene="gyrB"
                     /locus_tag="TV193_000916"
     CDS             12966..14918
                     /gene="gyrB"
                     /locus_tag="TV193_000916"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEL1513129.1"
                     /translation="MVEENKQLEDKAQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIQVFIEADNSITVIDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGHIHYQEFRRGAVV
                     DDLAIIGTTDVTGTTVHFTPDPEIFTETTEFDYQVLAKRIQELAFLNRGLKISITDKR
                     AGLEREEHFHYEGGIGSYVAFLNDKKDVIFDTPIYSDGELEGITVEVAMQYTTGYHET
                     VMSFANNIHTHEGGTHEQGFRTALTRVINDYAKKAKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGAEFDVSRARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGVNQEEE
                     LKAALERHSTGRSRPTIQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADRIF
                     DMLMGDRVEPRREFIEENAVYSTLDI"
     gene            15067..16791
                     /gene="ezrA"
                     /locus_tag="TV193_000917"
     CDS             15067..16791
                     /gene="ezrA"
                     /locus_tag="TV193_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEL1513130.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQAL
                     FGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFN
                     FIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
                     ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKH
                     EIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSI
                     KTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFL
                     STFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQL
                     LQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYE
                     KTRERIRF"
     gene            17159..17440
                     /locus_tag="TV193_000918"
     CDS             17159..17440
                     /locus_tag="TV193_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513131.1"
                     /translation="MKITKALCVAGAVAVLALAPISSSPAPTQTVFAATRGTEEYCHN
                     GWCSFLDEHGEWNTKREGESNSPLQRGSWWDWISYWSGYIWYSVYNWFR"
     gene            complement(17625..18080)
                     /locus_tag="TV193_000919"
     CDS             complement(17625..18080)
                     /locus_tag="TV193_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEL1513132.1"
                     /translation="MDSLDTRLLKGASGENRFDPDQQRYYLGTYAERIVLALPLTEVD
                     HEKAKGYITAQLPHLKEAYFPLSFKLSSEFGSAYQMYYMKLAQQNALSATIVDEKGAV
                     SPFALIIHSDHAITKEETNLKAILDKPSDNKPAEQTKTKGKSLWQRLFH"
     gene            18311..19618
                     /gene="eno"
                     /locus_tag="TV193_000920"
     CDS             18311..19618
                     /gene="eno"
                     /locus_tag="TV193_000920"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEL1513133.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWEGWKALTERLGKRVQLVGDDFFVTNTEYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(19754..19990)
                     /locus_tag="TV193_000921"
                     /pseudo
     CDS             complement(19754..19990)
                     /locus_tag="TV193_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20199..20420
                     /locus_tag="TV193_000922"
     CDS             20199..20420
                     /locus_tag="TV193_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEL1513134.1"
                     /translation="MSTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKIYHQAYAEYKADPETISHADFKKELGL"
     gene            20422..20682
                     /locus_tag="TV193_000923"
     CDS             20422..20682
                     /locus_tag="TV193_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1513135.1"
                     /translation="MYRIEYSKKAQKQIKKVDKQIQRLLFAWIDKYLEGTDNPRANGK
                     GLTGNHANEWRYRIGDYRLICDIQDDKMVVLALEFGHRKDIY"
BASE COUNT         6125 a         3928 c         4844 g         6227 t
ORIGIN      
        1 aaattgagac gaacagtaga ttgtagctat atcacaggtg agatagtaat gatcgtgcga
       61 aacaataaac tgatttttcc atgcgggata tttgttatca gtgagttgaa tggaactagc
      121 agctattgtt ttattgttag tcatctagtg tttttaaggt gcttattttc tgttacaaca
      181 gtgatgacaa caggttaagc taagttcgat ggagcttggt tttttattgt tacaagaaag
      241 ctcatagatg gtgattgcat tcttttatca tatgacaatg tttctatttt tgacaaatat
      301 tattgtcaaa aagtaaatga tctgttacac tggagttgga ctcatgaaag aaaaaagtaa
      361 tcagtaggat aacaataaca aagctatttt aagcttatac cattgtgtca atggattgtt
      421 gccggaaatg actggtgctt tctgttcaat caggagacag catttattag gagtgaagca
      481 tggcttatag gttgagaaat cggctcaagg agctacgagc tagagatggc attaatcaga
      541 cgcagatggc agcattagca ggtgtttcca ggcagaccat tagcctcatt gagcgaaatg
      601 aatacacacc atctattatt attgcaatga aaattgctaa agtatttaat gaaccaattg
      661 aacaagtatt tagcttagtg gagggcgaga gatgaaagct tttatgacgg aaaaggacag
      721 tacgttggtg agaatactta agtcattact gcttggatca gggattggct tagtgttagg
      781 tggccttgtt ggttttggtt tagctaggtt taacatatta gaaaatggct ttccgatatc
      841 agaagaagac accataactg gaataaagtg gggaatgaga ccccttgtta tcgtgcttat
      901 gctgctgagc atttatgata tttatcaagt tgtcaaagaa tatgctagat atgtcaagct
      961 aagcgatgat gaaacagagg agctgtaccg ttacattaat cttaagcatg cctatgcttt
     1021 aggatttagc gctatggcta tggtcttgaa tatagtcgtt ttttctttgg gatatagggt
     1081 gcctattgct aataatgcta gctatcttgg tttgactttt cctatttacg aggctctgat
     1141 gcttgtggtt attagtgttc tccatgctta tattttgaag gtttatactc ggattcgcgg
     1201 ggtcaagatg acgcttgctc ctaccttaaa ggaattaaag cagaatatct tacaacagga
     1261 cgaggcagaa ttgcaggcta attatcaaat gtcttttgag gttgtcttgg gccttagtgg
     1321 ctttatatta ccaggcattt acgtaatatt attgctttta tctatgattt ttcaaagggt
     1381 tgagctgacc ggactaatca ttactgctag tattcacctc tatattctgg tgaaatcctt
     1441 taaatcagca catgattttt ataggtaagg cgtaaggttt tacctactca agaattgtta
     1501 tacagcaaaa aagctttgat aagccattac tggcgatcaa agctttttgt gtttgttgaa
     1561 aaagaggctt ttttgaaaga gctgttggct gagatagctt gtcaaaccta caattgcaag
     1621 cggcacaagg ctaatgagag gttgtccggt aatttcaatg agaaaaagag gagcagtaag
     1681 aggtatctga ttaatgattc ccaaaaagag ggtcgctcca atgacaatgg ccaagggaag
     1741 tggtacagag agataaccta gctgattgct aaggcttgcc agtagcaagc cactagctcc
     1801 tccaagcatc atagaaggag caattttgcc tcctttagct ccagaggcaa atactgcata
     1861 gacagcagct gctttactta gtaagagcga ggcggtataa gataggctga catcatggtg
     1921 tagcagcagg aggagaccgg ccttgccatt gcctaaaatc tctgggaaat aaaggcttaa
     1981 acaagcacta aagccaaaag cccctaagac acgagggata aaccatcggc tcttaggctt
     2041 tgcctttggt gcgttttgga gcagctgctg gtagcaaaag gccagaaatg ctaagatggg
     2101 actggcaatg atagcccaaa ggactgttgt cagttgccag gcttgtggga gaatgagata
     2161 ctgtatgtcc tgatgtccgc ttagaacaag cacactttga acagcagtaa aggcagttat
     2221 agctgccgcg taaatgtgtt taactgagca ttttttgaca atagcctcca tgataaagac
     2281 aatcgtagct aatggtgcct ggtaaacagc tccaagggca gctcctgaag cacaggctaa
     2341 aagcaatcct tgctctgctg ctgatgcgtt tatagcttta ttgcaagcgg cagtcagtgc
     2401 cacagcaacc tcacgtgaag caccttcacg accgacaggt gctcccatgg agacggttat
     2461 taattgcagc cagccatgac aaaattgtgt ccaagggctg aaatcctttt gctgactgag
     2521 tgtttgttgg ataggctgaa taggcttggc ttttttagca agtagctgcc agccgagacc
     2581 agcaatagct ccagccaaca atagagataa aaaacgcctt tctggagcta ccgttgcaat
     2641 catggtgcta aaagacccag attggtatcc aaagctaata gcctgtatga aatgaatggc
     2701 ttgagtgagc acgtaagcca ccacaccagc aatcacacca gctaccacca gttggcccgt
     2761 ccatgttaag aaagtaatca atcgagtaat catatctttt attatagcag ataaaaagag
     2821 cctgagacta ctcaggctcc aaaatataga taaatccaat cttcatgaga agctggactt
     2881 atagcccata attgtaatcg tcatcagtca tagcttcaac agtaccaaga aggtagccat
     2941 taccaacttg agagaagaaa tcgtggtttg acgtgccggt tgaaatacca ttcataacga
     3001 ttgggttgac atcattggca gtgtctggaa aaagagggtc ctgaccaagg ttcatcaaag
     3061 ccttgttagc gttgtagcgt aggaaggtca tcacttcctc ggtccagcca acctcatcat
     3121 agagggtctt ggtgtattgc tcttcatttt catatagctg atacagcagg tcatacatcc
     3181 agtcacgaag gctttcttgc tcactctctg atagctcatt aaagcccagc tgaaacttgt
     3241 agccgatata agtgccatga acggactcat cacgaatgat gagcttaata atttcagcga
     3301 cattagccag cttattgttg cccagataat agagtggtgt aaaaaagcca gaataaaata
     3361 gaaaggtttc gagataagtc gaggctacct ttttttgaag ggcactgcca ttttcataaa
     3421 tgtcgttgat tatcttagcc ttattttgaa gaaatacgtt gttgttggtc cactcaaaaa
     3481 tgtcttcaat ttcttttttg gtgtttaggg tcgaaaagat tgatgagtag gatttagcat
     3541 ggacagactc cataaattgg atattgttaa gaactgcctc ttcatgcggg gtgcgcacgt
     3601 ccttgcgaat ggcttcgact cctgactcag actgcatcgt atcaagaagg gttagcccgc
     3661 caaagacctt acctactaaa tccttttcaa cagcagataa tctgcgccag tcatcaaggt
     3721 catttgatag tggaatacgt gtatcaagcc agaattgctc cgtcagcttt tcccaggttg
     3781 acttgtcaat gacatcttcg atttcattcc agttgattgc ttcatagtat gtggtcatga
     3841 gtttctccgg tagattgtaa tatagggtta ggtatgctag gaggagagcc ttgagtgctg
     3901 gtctatcatt aggacaggtg cactgacaca tcagctaggc tctgacatta aggactggtc
     3961 cacctcactg ccattcactt ggttagatga cacagctttc acactgattg gctccgacct
     4021 cctcgccatc atcggtaaag gtgcggatat aatagattga ttttatccct ttattaaagg
     4081 cgtaatgtct caaaatagat aggtcacgag tggtttgctt gctttctgtt ttccattcgt
     4141 agagctcctt tggcaattcg ctgcgcaaaa agagtgttaa cgacagtccc tgatcaacat
     4201 gctttgtagc agctgcatag acatcaatca cctttctcat gtccatatca taggcagatg
     4261 tgtagtaagg aatggtgtct gtagataggc cgttggctgg gtaataaatc ttgccgattt
     4321 tcttttcctg acgttcttcg atccgctgag taatcgggtg aatagaagca gagcagtcgt
     4381 tgatatagga aattgatcca ttaggagcaa ctgccagacg gttttggtga taaaggccat
     4441 ctgtcataat cgcttgacgc agcgccttcc agtctgctgc ttgcggaata aagtgatcct
     4501 tgaaaaggct tttaaccagc tctgattttg gcacacattc tcctgtgatg tactggtcaa
     4561 aataagcacc gctagcatat gttgattttt caaagccaac aaaggttgtc tgacgctcgc
     4621 gagcgatctg attggattcg acaagcgtcc agtaattcat cagcataaag taaatatcag
     4681 taaattcgat agattctggg ctgccatatt cgatatggtg ctgagccaaa taggaatgaa
     4741 gccccatagc cccaaggcca aaggtatgtg cttgactgtt accattttta acagttggga
     4801 ctgcttcgat attagaggag tcagtgacaa aggtcagggc acgtgtcatg gctctgatgg
     4861 aacgaccaaa gtcaggtgac gtcatcatgt ttaagatatt agttgatccc agattgcagg
     4921 aaatatcagt tcccattttg acaaactcct gcgcatcatt aatgagacta ggcgtttgaa
     4981 cctgtagaat ttctgagcat aggttgctca tgatgatttt accgtcaata gggtttgacc
     5041 tgttggcagt gtcgatgttg ataacatagg gatagccaga ttcctgctgg agcttggaaa
     5101 tctctgtctc caaatcacgt gctttgattt ttgttttggt gatattagga ttggcaacca
     5161 attcgtcata catgctagta atatcaatgt agttaaatgg caggccgtat tctctttcaa
     5221 cactataagg gctaaagaga tacatgtcag cattgtgacg agcaagctca taaaacttat
     5281 ctggtacagt aataccaagt gacaatgtct tgacccgcac cttttcatct gcattttctt
     5341 ttttggtaga caaaaaagcg ataatatcag ggtgaaagac gcttaaatac accacaccag
     5401 ccccttgacg ctgccctagc tggttggaat aagaaaagct gtcctcaaat agcttcatta
     5461 caggcacaac accagaagca gctccggcat agcccttgat tggagcgcca gcctcacgaa
     5521 ggttggatag gctaatgcca acaccacccc caatacggga taattgcaag gcagaattaa
     5581 tagagcggcc aatggcattc atatcatctg tcacctgaag gagaaagcaa gaaaccagct
     5641 caccacgacg gctccgtcca gcatttaaaa aagaaggagt agcaggttgg taacgctgat
     5701 taatcatctc aatggctaag tccttagcta atgtttcatc accatcagca aaataaaggg
     5761 cattgaacat gacccgatcc tctatgctct ctaagtagaa attgccatca ttggttttta
     5821 gggcatactg ctgataaaat ttataggccg ccataaatga tttaaagcga aagccctctg
     5881 cttgaatgct cttggctaga tggctgataa attcaggaga atagttttgg ataaaggctg
     5941 attcaatata gtcattgtct acaagatagg caatcttttc gttgatagaa gaaaatgaca
     6001 tggtgttagg aataacattt tcggtaaaaa aagcctccaa agcttccttg tctttatgaa
     6061 gtggaatgct gccatcaaca ggacggttaa tttcattgtt gaggcgaaag taagaaatat
     6121 cgccaagatc tttgagactc atatcaattg ttccttgtct agttaaataa tatcttttaa
     6181 ttttgctggc tgaaaccctg agaatactat ctgctctgtc tcaataacag gagcagcagt
     6241 aaagccaagg ctcttaacat agtccacttt ttctggatgc tcatcaatat taatctcttg
     6301 gaaagcagct ccatgctgtt ctaaaaattt cttagtcatt ttgcactgca tgcaattgtg
     6361 ctttgagtat actgtaatca ttgctcgtcc ttccaactat tagtctttca ctcaatttta
     6421 ggaaaaatca aatgactcta ataggatata aaaaatgttc ctaaaaagca aacgatttat
     6481 ttcagaatag cacaagatat tgtggttgtg tgtgagaata tttctaaata ttgtgttatc
     6541 ctctcttatc actgataatt gctacaagag gcttgtagtt cttaaatgca tactaatcag
     6601 gttggaaggc ttatttgaca ttatgaaaat catcatgtaa gaaatattga caacaaatga
     6661 aaatacaaga aaactgtttc atgatttttt cttgttagaa catttaacct tgaaaataaa
     6721 aaagcattgt gctataatca cttattgtaa gggttatcat gtgatagctc gaaaatacac
     6781 aattcaaaag gagaaccata ttatggcttc aaaagacttt cacattgttg cagaaacagg
     6841 tattcatgca cgcccagcta ccttacttat tcaaacagca agcaaatttg cttcagatat
     6901 tacacttgac tacaaaggta aagcagtaaa tcttaaatca atcatgggtg ttatgagcct
     6961 tggtgttggt caaggtgctg acgtaacaat cacagcagaa ggcgctgatg cagatgacgc
     7021 tattgcggca atcgaagaaa ctatgactaa agaaggattg gcataagact atgacagaaa
     7081 tgcttaaagg aatcgcagcc tctgacggtg ttgctgttgc caaagcatat ctgctagttc
     7141 agccggattt gtcatttgag actatcacag tcgaggatac aaatgcagaa gaagctcgcc
     7201 ttgatgttgc actacaagct tcacaagacg agctttctgt tatccgagaa aaagcagtag
     7261 aaagcctagg cgaagaagcg gcagcagttt ttgatgccca tttaatggtt cttgctgatc
     7321 cagagatgat cagccaaatt aaagagacta ttcgtgcgaa gcaaacgaat gctgaaacag
     7381 gtctaaaaga agtgactgac atgttcatca caatctttga aggcatggaa gacaatcctt
     7441 atatgcaaga gcgtgcggct gatattcgag atgtcgctaa gcgcgtcttg gctcatttat
     7501 taggtgttaa gcttccaaat ccagctacaa ttgatgaaga agcaattgtt attgcacatg
     7561 atttgactcc ttcagatact gcacagctta acaaacaatt tgtaaaagca tttgtaacga
     7621 acattggcgg acgtacgagt cattcggcta tcatggcccg tacacttgag attgcggctg
     7681 tgcttggtac aaatgatatt actaagcgtg tcaaagatgg tgaccttatt gctgttaatg
     7741 gtatcactgg tgaggttatt attgacccaa gtgaggagca gattcttgct ttcaaggaag
     7801 ctggagaggc ttatgcgaag caaaaggctg agtgggctct gcttaaggac gcacaaactg
     7861 tcacagcaga tggcaagtac tttgaattag cagcaaacat cggtacacct aaggacgttg
     7921 aaggtgtcaa cgataatggt gctgaggcgg taggtcttta ccgtactgag tttctttata
     7981 tggattctca ggatttccca accgaagatg agcaatatga agcctacaag gctgttcttg
     8041 aaggaatgaa cggcaagcct gttgttgttc gtacaatgga tatcggtggg gacaaggagc
     8101 ttccttactt tgatttacca aaggaaatga acccattcct tggttttcgt gccttacgca
     8161 tttcaatctc tgaaacaggt aatgctatgt tccgcacaca aattcgtgct ttgctgcgtg
     8221 cttctgtgca tggtcaattg cgtatcatgt tcccgatggt tgcccttcta aaggaatttc
     8281 gtgctgctaa agtcgtattt gaagaagaaa aggctagctt gctgtctgag ggtgttgcgg
     8341 ttgcagacga tattcaggtt ggtatcatga ttgagatccc agcagcagca atgcttgctg
     8401 accaatttgc caaggaggtt gacttcttct caattggtac aaatgacctt atccagtaca
     8461 caatggcagc agaccgcatg aacgagcaag tgtcatacct ttaccagcca tataacccat
     8521 caatccttcg tttgattaac aatgttatca aagcagctca tgctgaaggt aagtgggctg
     8581 gtatgtgtgg tgaaatggca ggtgaccaac aggctgtgcc gcttcttgtt ggtatggggc
     8641 ttgatgaatt ttcaatgtca gcaacatctg tgcttcgcac acgtagcctg atgaaaaagc
     8701 ttgattcagc gaaaatggca gagtatgctc atcgtgcact cacagaatgc tcaactgctg
     8761 aagaggttct tgagcttgcc aaagagtata ttacagaagc ttaaatagaa ataacgagga
     8821 gctggttttg tccggctctt ttttactaga aaaatgacta atcagatcca tatgaaagct
     8881 tgctttataa agtagtttga tgtttcaagt tttatcagaa ttttcagact cttcctgtag
     8941 cgaattgttg aaatatgcta aaaaagtgat agaataatag taccattata aaaggagaaa
     9001 aaagtttggc taaacaatat aaaaatttag tgaatggtga gtggaagctc tctgaaaatg
     9061 agatcaagat ctatgcacca gcaaccggcg aggagttagg tagtgtacca gctatgtctc
     9121 gtgaagaggt tgatcaggtt tatgcgtcag ctcgcgctgc tcttgcagat tggagagcgc
     9181 tttcttatgt tgagcgtact gcttatttgc acaaggctgc tgatattttg gtgcgtgatg
     9241 ctgagaagat tggtgctgtt ctctcaaaag aggttgcaaa gggttataag gctgctgtta
     9301 gtgaggttat tcgtacagca gaaattatta actatgcagc agaagaaggc cttcgtatgg
     9361 aaggcgaggt ccttgagggt ggcagctttg aggctgctag taagaaaaag attgcgatcg
     9421 tacgtcgtga gccagtggga cttgtgcttg cgatttcacc cttcaattat ccgattaacc
     9481 tagcaggctc aaagattgct ccagccctta ttgcaggaaa tgtcgtggtt cttaagccgc
     9541 cgacacaagg ctctatttct ggcttgctct tagcagaggt atttgcagaa gcaggtcttc
     9601 ctgctggagt ctttaatacc atcactggac gcggctcagt tattggtgat tacatcgttg
     9661 agcatgaggc tgtaaacttt atcaacttta ctggctcaac gccaattgga gagcgaattg
     9721 gtaaattagc cggcatgcgt ccgattatgc ttgagcttgg tggtaaggat tcagcgattg
     9781 tcttagaaga tgctgatatt gccttagctg ctaaaaacat tgttgcaggt gcctttggct
     9841 actcaggtca acgctgtaca gcagttaagc gtgtgcttgt tatggaaagc gttgcagacc
     9901 agctggtagc agagattaag ggcttagttg agaaattact tatcggtatg ccagaggaca
     9961 atgctgacat cacaccattg attgatacca aagcggcaga ttttgttgaa ggtctggtta
    10021 atgatgcagc agacaaggga gcacaggcgc ttactgaaat caagcgtgac ggtaatttaa
    10081 tttgtcctat cttgtttgat agagtaacaa ctgatatgcg cttggcttgg gaggagccat
    10141 ttggtccggt gctgccagtg attcgtgtaa gctctgtaga agaggcaatc agcatttcaa
    10201 atcaatctga atacggtttg caagcgtcta tctttacgac taattttcca caggcctttg
    10261 ctattgctga gaagcttgag gttggtacag tacacattaa caacaaaacc caacgtggta
    10321 cagataattt cccattccta ggggctaaga aatcaggagc tggtgttcaa ggggtcaaat
    10381 attcaattga ggcaatgaca agtctcaaat cagtcgtatt tgatattcaa taacaaaaaa
    10441 gctagggtat cttagtttga aagcagttgc acatttgtgc ggctgtttta tttgtgtctc
    10501 tagttttaac agctagctat gcaagaaggt gagttgtccc aacctcaaag atgagatcta
    10561 aatatttaat gattttgggg tcgtaaaaaa gtttagagtg ttttgatctc cttaagatgt
    10621 gagtgtacaa agtctcgcca acagccagca ggactagcca ttgaggtcaa ggaagctgct
    10681 aaaatagctg atggttcaaa agcttggtga aaggcttaat atctatcatt gctattttga
    10741 gggctttcca ttataatatg aatactagag ctacttgtcg gtctgcctct tgagctgtga
    10801 gatagctgtt ggatttagtt gtctccttgt ccacaaaagg cttagaggca aaggctgtgg
    10861 ctatgcttct tgcttctttt agtgaagtgt atgagatctt atgaaaactc atataggctt
    10921 tggtatcttt gcaagaggac taatggcttg ctttacttgc cttgatagag ggctgggatt
    10981 gaggggtgat gacctgcggt ggtcatctct agagctcctt gcttcttttt ttatgtagac
    11041 taatggttta gactgctagc ttccttgttt agaaagtagg acatcatgtt acccaagaga
    11101 aaattaattg atcaacgtct tgattatgcc attatttttc ctgttttttg tttgctaata
    11161 tttggtctgg tatctgtata tgtggcagca agtcatgatt ttccgcaaag cctcgccact
    11221 gttatgcttc aacaggttct ctggatcctt cttggagctg tgattgcctt taccctaatg
    11281 ttttttagca cagagattct gtggaaatta acacctgtct tttatctttt gggtgtgcta
    11341 ttaatggttc tgccactcat cttttttagc cctcggctgg tagctgctac aggggcgaaa
    11401 aattggatta cgattggctc aacgaccttg tttcaaccat cagaatttat gaaaatatcc
    11461 tacattctgg caatgtcttg gttaacggtc tggtttaaga gaaagcagga gagaagtcgg
    11521 tttttagatg attggaagct cttgggctta taccttgtct tgacgttgcc ggtcatggtc
    11581 ctgctagcac tgcaaaagga cttaggaaca gctatggttt ttttagccat cttagctggg
    11641 attatcttaa tttcaggaat ttcttggtgg cttattttac cagctttggt actagtcttt
    11701 ttactggttt cagctttttt ctttgttttt ttgttgccag agggaaaaga attcctttta
    11761 aaaatgggaa tggataccta ccaattgaat cgtatttcag cttggctgac accgtttgat
    11821 ttctcagata ccattgccta tcagcagacg caaagtatga tttcgattgg gagtggtggc
    11881 ttttttggta agggctttaa tcagcttgag ctgtcagtac cagtcagaga aagtgatatg
    11941 atttttacag tgatcgctga aaattttggc tttcttggtg cagctagctt actgatcttg
    12001 tatttaatac tgatttaccg catgcttagg gtgacctttg catcgaataa ccttttttat
    12061 acctacattt caaccggctt tatcatgatg atactatttc atatttttga aaacattggc
    12121 gcagcagttg gtctgctacc tttgaccggt attccccttc cctttatttc tcagggcggc
    12181 tcttccttga tttcaaatct gattggggtc ggcctgatcc tatcaatgaa ctatcagcac
    12241 gtccttgctc atgaaaagca aagcgagcat gagcttagca gaagctcacg ttatgtttaa
    12301 gaggcatgtt tggtccttgt tcggttagaa tgagctgcca atcagccctt ttttatttgc
    12361 ttaatcgcta taaaaataaa gaaaaatatg ttataattaa ggttatgaat tatcatgatt
    12421 atatttggga tttgggcggc actctcttgg ataactatga aatttctacc caggctttta
    12481 ttgagacgct gcattttttt aagctgtctg caagccacga tgccgtttat caaaggctta
    12541 agaaatcaac agcaaccgcc attcaagtat ttgctcccaa cgaaccgcaa tttttacaat
    12601 attacaaagc gaatgaggct aagaaattag ccaatcctat ttggtgccta ggtgcaaagg
    12661 acattctaaa gaggattgtg gcatcaggct cgcgtaattt tttaatatcc catcgtgatc
    12721 atcaggtcaa tgatttgctg gagcaggctg ggcttttggg ctattttacc gaggttgtta
    12781 ccgcctcaaa tggctttgcc agaaagccta accctgagag cttactttat ttgaaggaaa
    12841 agtacctgat cagcaagggc ttagtgattg gtgatcgcag acttgatata gaagcaggac
    12901 aagcagcagg ctttgacacc ctgcttgttg atggtagaaa aaacctattg gagatagtag
    12961 attagatggt tgaagaaaat aaacaattag aagacaaggc tcaagagtat gacgctagcc
    13021 agattcaggt cttagagggg ttagaagccg ttcgcatgcg tcctggaatg tatattggct
    13081 caactgccaa ggaaggctta catcacctag tttgggagat tgttgataat tctatcgatg
    13141 aagccttggc aggctttgcc agtcatattc aggtttttat tgaggcagat aattcgatta
    13201 ccgttattga tgatggacgt ggtatcccag ttgatattca agctaagaca ggccggcctg
    13261 ctgtagagac agtttttaca gttttgcatg ccggtggaaa atttggcggt ggtggctaca
    13321 aggtttctgg aggacttcat ggtgttggct cctcggttgt taatgcctta tccacacagc
    13381 ttgatgttcg tgtctataaa aatgggcata tccactatca ggagtttagg cgtggtgctg
    13441 tagttgatga tttggctatc attggaacga ctgatgttac gggaacaaca gtgcatttca
    13501 cacctgatcc agagatcttt acagaaacaa cagaatttga ctaccaggtc ctggcaaagc
    13561 gtattcaaga gctggccttt cttaatcgtg gcttaaaaat ctcaattaca gataaacgag
    13621 ctggtcttga aagagaagag catttccatt acgagggtgg tattggctct tatgttgcct
    13681 ttttaaatga caaaaaggac gtcatcttcg atactccgat ttattctgat ggtgagctgg
    13741 aggggataac agttgaggtg gcgatgcagt acactacagg ttaccatgag actgttatga
    13801 gctttgccaa caatattcac acacatgagg gtggtaccca tgagcagggc tttagaacag
    13861 ctctgacgcg cgtgattaat gactatgcta agaaggctaa gattctcaag gaaaacgagg
    13921 ataatctgac aggtgaggac gtccgcgagg gcttgactgc tgttatttct gtcaagcacc
    13981 caaatccaca atttgaaggg caaacaaaga caaagttagg aaattctgag gttgttaaga
    14041 ttaccaatcg cttgtttagc gaagctcttc agcgctttct actagagaat ccgcaggttg
    14101 cccgtaagat tgttgaaaag gggattctag cctctaaggc tcgcattgct gccaagagag
    14161 cgcgtgaagt aacccgcaaa aaatcaggcc tagagatttc caatttgcca gggaagctgg
    14221 ctgactgctc ctcaaatgat gctagtcaaa atgagctttt tatcgtggag ggggattcgg
    14281 ctggtggatc agcgaagtca ggtcgcaatc gtgagtttca ggctattctg cctattcgtg
    14341 gtaaaatttt aaacgttgaa aaagcaacga tggataaaat ccttgctaac gaagaaatca
    14401 gaagcctctt tactgctatg gggacaggct ttggagcgga gtttgatgtt tctagagctc
    14461 gctatcaaaa gctggtcatc atgactgatg cagatgtcga tggagctcat atcagaacgc
    14521 ttttgttaac gttgatttat cgcttcatgc gaccagtatt agaggctggc tatgtttaca
    14581 ttgctcagcc accgatttat ggtgttaagg ttggcagcga gattaaggaa tacattcaac
    14641 cgggagtcaa ccaagaagag gagctaaagg ctgctcttga aagacatagc acaggacgct
    14701 caaggccgac tattcaacgc tataagggcc taggagagat ggacgatcac cagctttggg
    14761 aaacaacaat ggaccctgat aatcgtctaa tggcacgtgt gaccgtagat gatgcggcag
    14821 aggctgatcg gatttttgac atgctgatgg gcgatcgtgt tgagccaagg cgtgaattta
    14881 ttgaggaaaa tgcggtctat agtacgcttg acatttagtc aaatatattt tgaaaagcac
    14941 ctaaaagtat gttataatcg taacgttata gtgtattttt gataatataa taaaaggcga
    15001 ttcttgctag ttgttcctac tgaaccggca gttgatcaat cgcatctaaa taataaggag
    15061 attaagatgt caagcggaat tatcttgctg attgtggcca tagtcttact agtgattatt
    15121 gcttatttag tgggtgttat tatacgcaag cgtaatgaca cattaattac cagtctagaa
    15181 gaacgaaaac aagctttatt tggccttcct gttaatgacg aaatcgagga agtcaagtct
    15241 cttcacttga ttggtcaaag ccagacctca tttcgtgaat ggaatcaaaa gtgggttgat
    15301 ttgaccctaa atacctttac cgatattgaa aagcatatct ttgaggctga gcacttaaat
    15361 gacaccttta atttcattcg tgccaagcat gagattaata gcgttgagag tcaattgaat
    15421 ctcgttgaag aggatattac cgctattcgt gaagcacttg gcatattaaa ggagcaggaa
    15481 gaaaaaaaca gcgcgcgtgt tactcatgca ctagatttgt acgaaaagtt gcaggcttcc
    15541 gttgctgaaa atgaagataa tttcggatca acaatggccg aaattgaaaa gcaaatgaag
    15601 aatattgaag cagagttttc acaatttgtt gcccttaatt catcaggtga ccctgttgaa
    15661 gcagcggagg ttttggataa ggctgaggag catacgattg ccttggggca aattacagag
    15721 cagatccctg ctattgtagc aaagcttgaa gatgattttc cggatcaatt ggacgatctg
    15781 gagacaggct atcgtcgttt gctggaggaa aattatcact tcccagaaaa aaatattgaa
    15841 gcccgctttc aagagattcg tgagtctatt cgtgccaatt catcagagct ggttaccctt
    15901 gatttggacc gagctagaga tgaaaatact cacattcaag agcgtatcga ctcactgtat
    15961 gagctctttg agcgtgagat tgcagcctac aaggtggttg ctaaaaatag caaaatatta
    16021 ccaagatacc tggctcacgc caagcacaac aacgagcagt tgaagcatga gattgctcgt
    16081 ctatcacgta agtatatctt gagtgaaaat gaaggcttaa atatcaaggc ctttgacaaa
    16141 gacctcaaag atatcgaaga caatgtcctt gagattgctg aagcctttga tcagcaggaa
    16201 aagccatttt cagagctaca gctgattctt gatcgtagta tcaagacgtt ggcttctgta
    16261 gagtctggtc agatggacgt ctttgctgct gttaaagaca ttgaaaagat tgagtcacag
    16321 gctcgccagc acttagaaat ctacgtcaca cagcttcaca tgattaagcg ttatatggaa
    16381 aagcgcaatt taccgggaat tccacaggat tttctgagta ccttctttac cactagttcg
    16441 cagctagaag cattgatgga cgaactaagt agaggacgta tcaacattga agcggtgtcc
    16501 cgtctgtctg aggtggcaac agctgctatt gctaatctag aagagctaac ctaccaagtg
    16561 gttcagcatg ctaccttgac agagcagctg ctccagtact ctaaccgtta tcgttccttt
    16621 gaagctggcg tgcaaaatag ctttgagcat gccttgaaat tgttcgaggt ggacaatgac
    16681 tatcaggcat catttgatga gatttcctat gccttggaga cagtcgagcc aggagtgaca
    16741 gagcgttttg tcaattccta tgagaagaca cgtgaacgta tccgcttcta atgtgacaag
    16801 ggttgatact ttatattacg aaaaagcttg aaaaagcagt ccatgctggg ctatgctttt
    16861 tcaagctttt tgaatggtca ggctatggcc tccttgagct atacccaaaa agctggttca
    16921 agccagtcag tagagataga caaggcctta gtgctattgg gctgttgcta catgagatat
    16981 tttgtaataa aatcagacga ttatccattt aattaaaaaa aaaaaacgaa actgcggagg
    17041 aaacctgacg agtaactatt tatggctatc aatcagcatg ttacactctt tttggaaggc
    17101 ctagcaatca ctgactgtga ggttaaccaa agaaaataag atgttaagga gaatatcaat
    17161 gaaaataact aaagcattgt gtgtagcagg tgctgttgca gtcctagcct tggcaccaat
    17221 cagctcaagt cctgcaccaa cacagactgt atttgctgct acacgtggta ctgaagagta
    17281 ctgtcataat gggtggtgca gttttcttga tgaacatggt gagtggaaca cgaaacgtga
    17341 gggcgaatct aatagtcccc tacagcgagg ttcatggtgg gattggattt cttattggtc
    17401 tggttatata tggtattctg tatataactg gtttaggtaa cctctcaacg ccactgctac
    17461 catactgata aatcccttag actattctaa gggattttta ctgcaaaaag cacataggga
    17521 caaggcaata caagctccag cctgttctta gctccctata ccggtaagga tcataacact
    17581 cagaactccg gcagatgatt gcaggagcta ttggagagtg aggactagtg aaagagcctc
    17641 tgccagaggg atttgccctt agtctttgtt tgttcagcag gcttattgtc agagggcttg
    17701 tctagtatag ccttgagatt ggtttcctct ttggtgatgg catgatcact atgaatgatc
    17761 agagcaaaag gagagacagc tcctttctca tctacaatag tggcagatag agcgttttgt
    17821 tgggccaatt tcatatagta catttgataa gcagagccga attcagagga taatttgaat
    17881 gacaagggga aataagcctc tttgaggtga ggcagctggg ctgtgatgta gcctttagcc
    17941 ttttcatgat caacctctgt caagggaagc gctaagacaa tcctttcagc ataggtccct
    18001 aaataatagc gttgttggtc ggggtcaaat cggttttctc ctgaagctcc ctttaagagt
    18061 cttgtatcta atgaatccat acaatccttt caagcatgtg atactgtcat tatactatta
    18121 actgcgccaa ataccaatga taaagcattt actaggtatt tgatcggctt ttggaagaag
    18181 atgaaatcaa agaaaaacag catgaaaaca actctcttat ttcatgaaat tagtttttaa
    18241 gttgcttaag accctagttt gtggtattat taacatgtaa aatattaaaa ctcataagga
    18301 gagtattata atgtcaatta ttactgatgt ttacgctcgc gaagtccttg actcacgcgg
    18361 taacccaaca cttgaagtgg aagtttatac tgaatcaggt gctttcggac gtggtatggt
    18421 tccttcagga gcttctactg gtgagcatga agcagtagaa cttcgtgatg gcgacaaatc
    18481 tcgttacctt ggtcttggta ctcaaaaggc agttgacaac gttaacaaca ttatcgctga
    18541 agcgatcatt ggttatgatg ttcgcgatca acaagctatt gacagagcca tgatcgctct
    18601 tgacggtact ccaaacaaag gtaagcttgg tgctaatgct attcttggtg tgtctatcgc
    18661 tgtagcgcgt gctgctgctg actaccttga ggtgccactt tacacttacc ttggaggatt
    18721 caatactaag gttcttccaa ctcctatgat gaatattatc aacggtggtt ctcactcaga
    18781 cgctccaatt gctttccaag agttcatgat tatgccagtt ggtgcaccta ccttcaaaga
    18841 aggtcttcgt tggggtgctg aggtattcca tgctcttaag aaaatcctta aagcgcgtgg
    18901 acttgttact gctgttggtg acgaaggtgg atttgctcct aaatttgaag gaactgaaga
    18961 tggtgtagaa acaatcctta aggctatcga agctgctggc tatgaagctg gtgaaaatgg
    19021 tatcatgatt ggttttgact gtgcgtcatc agaattctac gataaagagc gcaaagtcta
    19081 cgactacact aagtttgaag gtgaaggcgc tgctgttcgt acatctgcag agcaaattga
    19141 ctaccttgaa gaattggtta acaaataccc aattatcaca atcgaagacg gtatggacga
    19201 aaatgactgg gaaggctgga aagcacttac tgagcgccta ggcaaacgtg ttcaattggt
    19261 tggtgatgac ttcttcgtta caaacactga ataccttgct cgtggtatca aagaaggtgc
    19321 agctaactca atccttatca aggttaacca aatcggtact ttgactgaaa cctttgaagc
    19381 tatcgaaatg gctaaggaag ctggctacac tgctgttgta tcacaccgct caggtgaaac
    19441 tgaagattca acaatcgctg acatcgcagt ggcaacaaac gctggccaaa tcaaaacagg
    19501 ttcattgtca cgtactgacc gtatcgctaa atacaaccaa ttgcttcgca tcgaagatca
    19561 acttggtgaa gttgcacaat acaaagggat caaatcattc tacaacctta aaaaataatt
    19621 tgattttaga ttaaaaggtt gacaagcctt gattttaaag cattctagga ctgtcctaga
    19681 gtgcttttag ttttagcttc atgtcaactg tagtgggtga ctgatagcta agcacgagag
    19741 gagacgaagg tcgccttctc tttttcaatc ggataaggct agggaatccc caaatgtcga
    19801 tgaagggaat tttagaaggt ttctggaagt cgtatatgat ttgtttccct ttgcagtgtc
    19861 tacacctagg agactgatag tccagtgtag cgctgacttc gatatgagta tcgtgctgga
    19921 tagtcttatt caaggtgata ttttgatctt tgattccgat gagtagtgtg gtatgatgaa
    19981 tctgttccat aagacacttt ctaatgatgg tctggtcgct tttcatgata agccttatgg
    20041 aactttttgg gtactcaaaa agccctataa tcttcataat gaatttaccc attacagaaa
    20101 ttatagagcc aatatttaga ggattttagc ctattggtag attgacagtt tcttaagatt
    20161 gtgttacaat gtaacacaaa gaaacgaggt aaacgactat gagtacagtt actatcagat
    20221 taaatcaaga agaagaaata tttttcaaaa gttacgccca actcacaggg caaagtttat
    20281 caagtctatt taaaaaagcc cttgagcggg atattgaaga tgagtatgat ttaaaaatct
    20341 atcatcaagc ctatgctgaa tataaagcag accctgagac aattagccat gctgatttta
    20401 agaaagagct aggcttataa catgtaccgt atagagtatt ctaaaaaggc tcaaaagcag
    20461 attaagaaag tagataagca aattcagagg ttgctatttg cttggattga taagtattta
    20521 gagggaacag ataacccacg cgcaaatggc aaaggtttga ccggaaatca tgctaatgag
    20581 tggcgttatc gtattggtga ttataggctt atttgtgata ttcaagatga taagatggtt
    20641 gttttagcgc ttgagtttgg gcatcgtaaa gatatttact aacgttgagg aagtaagatg
    20701 gtcaaaaata atgcaattgg tagcaactgg aaagatgtaa gagctgagtt attcagcaag
    20761 gaagaatttt agaaagtgat gctcgtattg ctattatgga caagtatagt taaaaagtgt
    20821 gcgtttttaa tctgtatgat gaagtaattg ataaagtaac aggtcaaaag gctatcattg
    20881 tctgtattgc taataaattg gtagatgatt gttatttaat cgaaccgcta aaccattctt
    20941 acttaccaga ttggcgtgag ataaatcagt taattcgata taaaaattag caccttatcg
    21001 ggtgctaatt ccttgcctgc tgaactcata atttaatacc ttttttacta ccccatatgt
    21061 ttcccctaat tatgtgtact tgctagatat aaggttaatt gggatagaat tttgaataaa
    21121 gttg
//
LOCUS       DARYXS010000031        20422 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.031, whole genome shotgun sequence.
ACCESSION   DARYXS010000031 DARYXS010000000
VERSION     DARYXS010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20422
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.031"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(293..641)
                     /gene="ssrA"
                     /locus_tag="TV193_000924"
     tmRNA           complement(293..641)
                     /gene="ssrA"
                     /locus_tag="TV193_000924"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            732..1343
                     /locus_tag="TV193_000925"
     CDS             732..1343
                     /locus_tag="TV193_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1513136.1"
                     /translation="MRNNELKPYVIWQKVIKLLGSLALVGSFLLAFWFYRLGILNDSN
                     ALKDLVHSHKVFGPLVFVGVQIVQIVFPIIPGGMTTIAGFLIFGPLLGFLYNYVGIFI
                     GSVILFLLVKTYGRRFILLFIEEQTFYKYERKLEMPYYERLFILCMLSPISPADIMVM
                     ITGLTEMSLKRFVTIILITKPLSIIGYSYLFIFGKDLILWFFH"
     gene            complement(1390..2184)
                     /locus_tag="TV193_000926"
     CDS             complement(1390..2184)
                     /locus_tag="TV193_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513137.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAGVIAIAIVLSFTINTLTNNPDE
                     VGLTTSLANKMVPLTLSLTFGSLIAGSFLSTLLIIINRFNKNVFGREGYLTLTLPVTA
                     HQIILSKLLASFVCSIFNGINLLIGIFILIAPTVDFTYLLKVLKTIMKPENLVENASI
                     LIYMLLSTITSILLIYLAISIGQLFSNRRGLMAFCAYFILVIIIIVVMTYLNDAFFTV
                     NPNSSDSLLYFGDHTAISILNIEQLVEGIILYVATHFIIKNKLNIQ"
     gene            complement(2194..2892)
                     /locus_tag="TV193_000927"
     CDS             complement(2194..2892)
                     /locus_tag="TV193_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513138.1"
                     /translation="MAQLLQLHHVSKSYKKQLAIDDLTITIPSGKIIGLLGPNGSGKT
                     TLIKLINGLLQPDKGDIVIDGFRPSVETKKIISYLPDTTYLNESMKIKDMLDFFGDFY
                     ADFDRDKATSLLKDLDLDAEERFKNLSKGNKEKAQLILVMSRKAKLYILDEPIGGVDP
                     AARDYILKTIINNYSEQASVIISTHLISDIEPVLDEAIFLKNGKLCLSGNADDLRVQH
                     QQSIDSLFREIYKV"
     gene            complement(2892..3263)
                     /locus_tag="TV193_000928"
     CDS             complement(2892..3263)
                     /locus_tag="TV193_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1513139.1"
                     /translation="MSWKFDEKSPIYAQIAQHIMLQIVSQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRALTELDREGIVYSQRTAGRFVTDNQELIARKRRELAINELKSFISNMIK
                     IGFERSEIIPVLSTFLEEGSN"
     gene            3505..6615
                     /locus_tag="TV193_000929"
     CDS             3505..6615
                     /locus_tag="TV193_000929"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEL1513140.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLDHYFKQAKRLGYQAIGIMDQDNLY
                     GAYHFIKGCQRHGLQPILGLEVAITVKEQALTLKLVAKNDTGYQQLLKLSTEKMSGDL
                     DLDTLVQYLEGIAVIVPFSQSLRDLGLPFDYFIGIDEASDLSKIDSTERLIPLRTVRY
                     FDNAETETLQMLHAIRDNISLADTALVAKDQFLAPCQEMTAIFQEKCPEALVNLVNLT
                     ASIAYHFDTDLKLPRFNRDKPAKEELRELTESGLREKQLWKEPYQFRLAEELAIISDM
                     GFDDYFLIVWDLLRFGRSRGYYMGMGRGSAAGSLVAYSLRITGIDPVKNNLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLHYVRDRYGSEHSAQIVTFSTFGPKQAVRDVFKRFGV
                     PEYELTSLTKKIGFKDTLSTVYEKNIAFRQTINSRLEFQKAFEIAKRIEGNPRQTSIH
                     AAGIVMSDDHLTNHIPLKKGEDMMVTQYDASAVEANGLLKMDFLGLRNLTLVQKMQEK
                     VVNDYGLSIDIEAINLEDPETIALFARGDTKGIFQFEQHGAISLLKRIKPTSFEEIVA
                     TTSLNRPGASDYTQNFIKRRQGQENIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLVEMQRMQEDFLTGARALGRSEETARLLFARMEKFAGYGF
                     NRSHAFAYAALAFQLAYFKAHYPEVFFDVMMNYSSSDYITDALDFGFEAAQVTINTIP
                     FNDKIERHKIYMGLKNIKGLPREFSYWIIENRPFTSVESFLCSIPEKYQKTSFLEPLI
                     KIGLFDGFEKNRQKIINNLEGLLTFVNELGSLFADSSFSWVETEDYSAAEKYYFEQDL
                     LGVGMSKHPLLAVAEKSTVAVTPITKLVKDTEATLLVQIDAIRVIRTKSSGQQMAFLS
                     VTDTKQKLDVTLFPEQYAVYKQDLKEGHIYYINGRVKERDNRLQLVCHQLRLAQSQRY
                     WLLVENHQHDAAISDILTAFSGETPVIIHYQEGKETLELNHIRVDVSKDLEEAISPYV
                     LKTVFR"
     gene            6695..7708
                     /gene="pfkA"
                     /locus_tag="TV193_000930"
     CDS             6695..7708
                     /gene="pfkA"
                     /locus_tag="TV193_000930"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEL1513141.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIHKVVSTIKDDFENRGKNHHI
                     IVLAEGVMSGEAFAQQLKEAGDESDLRVTNLGHILRGGSPTARDRVIASWMGAHAVEL
                     LKEGKGGLAVGIHNEELVESPILGSAEDGALFSLTDEGNIVVNNPHKARLDYAALNRS
                     LAQ"
     gene            7770..9272
                     /gene="pyk"
                     /locus_tag="TV193_000931"
     CDS             7770..9272
                     /gene="pyk"
                     /locus_tag="TV193_000931"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEL1513142.1"
                     /translation="MNKRVKIVATLGPAVEIRGAKKYGEDGYWAGQLDVEQSAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLARQKVGFLLDTKGPEMRTELFADD
                     AKEYSYVTGERIRVATAQGIQSTRDMIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
                     IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNEHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     RPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            9401..9958
                     /gene="lepB"
                     /locus_tag="TV193_000932"
     CDS             9401..9958
                     /gene="lepB"
                     /locus_tag="TV193_000932"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1513143.1"
                     /translation="MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNK
                     GDLITIKKNIEPKYKDFVVYTVDKKDYVSRVVAVAGDRVTYMDDIFYLNNMVESQSYL
                     ESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
                     DVSQIKGLVTFRVLPLKDFGFVEVE"
     gene            10135..11946
                     /gene="glmS"
                     /locus_tag="TV193_000933"
     CDS             10135..11946
                     /gene="glmS"
                     /locus_tag="TV193_000933"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEL1513144.1"
                     /translation="MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNL
                     VKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVI
                     ENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
                     IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDS
                     ARVTDYAGNPIDRQSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQ
                     MMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLEHLTDTPVELGVASEWGYNMPL
                     LSKKPMFILLSQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKEL
                     IAEKVQTLLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLI
                     EDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIINKVHPFL
                     APIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            12130..12465
                     /locus_tag="TV193_000934"
     CDS             12130..12465
                     /locus_tag="TV193_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEL1513145.1"
                     /translation="MTLPNCLQCDSEYVYEDGHLLICPMCSFEWTRGEEEPEEEGLVV
                     LDSNGTRLADGDTVTIIKDLKVKGAPKDLKQGTRVKHIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            12572..13213
                     /locus_tag="TV193_000935"
     CDS             12572..13213
                     /locus_tag="TV193_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1513146.1"
                     /translation="MTYIMQVLPSLLDGALITLQVFFIVIVLSIPLGALLAFLMRVDF
                     KPLQWLLTLYIWVMRGTPLLLQLIFFYYVLPSVGVTFDRMPAAILAFTLNYAAYFAEI
                     FRGGIETIPNGQYEAAKVLKLSPVQTVRYVILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTILSKQVEKRFNYYQ"
     gene            13223..13852
                     /locus_tag="TV193_000936"
     CDS             13223..13852
                     /locus_tag="TV193_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1513147.1"
                     /translation="MLELNNISKRFGHKQIFDGFHLTVEDGEVLSLVGPSGGGKTTLL
                     RMLAGLEPIDSGNISYNGESVPIDHLEKRSLLGFVFQDFQLFPHLTVLDNLILSPTIT
                     MAMPRPDAKQKAMELLERLGLKEHAAAYPYALSGGQKQRVALARAMMIDPQIVGYDEP
                     TSALDSELRQEVEKLILQNREMGITQIVVTHDLQFAQTISDRIIKINPK"
     gene            13869..14705
                     /locus_tag="TV193_000937"
     CDS             13869..14705
                     /locus_tag="TV193_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1513148.1"
                     /translation="MTLKKTLLVALFAATATLLVACGASNKQTSSDAWDSYKQKKTIT
                     LGFDNTFVPMGYKDESGKNTGFDIELAKAVFDQYGINVKYQAINWDLKETELNNGKID
                     LIWNGYSVTKERQAKVAFTEPYMKNEQVLVTQKSSQISSFADMKNKTLGAQSGSSGYD
                     AFTSHPKVLKDLVKGNDATQYETFTQAFIDLKNKRIDGLLIDRVYANYYLQQEGELDR
                     YNIIASEFEGEDFAVGVRKADKTLQKKITQALKSLYQDGTFQKISKKWFGEDVATVQL
                     KS"
     gene            complement(14801..16039)
                     /locus_tag="TV193_000938"
     CDS             complement(14801..16039)
                     /locus_tag="TV193_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEL1513149.1"
                     /translation="MPNNPVENLRLAKRGPIVSIVTYLALSITKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVTLLIGLHLASQPADANHRFGHWKIEDLSSLITSFIMFIVGFQVLL
                     QTIQQMISGKQSAIDPLGAIVGIASALVMLGVYAFNKALSKKVRSSALVAASKDNLSD
                     AVTSIGTSIAIIAASLKLPIIDRLAALIITFFILKTAFDIFMASAFSLSDGFDSTQLK
                     AYEKAILKIPKIIAVKSQRGRTYGSNVYLDIVLEMHPDLSVYESHAITEQVEQLLSEQ
                     FAVYDIDIHVEPAKLPKDDNCEYVYKKLYKNEKIMLSQIPDYQELIAKTFTFIDRDGQ
                     AYNAKQFLEQQRSSSNQLEAFCMQSISHNTKLVTYQLQGNQHTSIWRRHEAWHLIYHQ
                     ITPITNSIAIKKHYHIKRIS"
     gene            complement(16142..17476)
                     /locus_tag="TV193_000939"
     CDS             complement(16142..17476)
                     /locus_tag="TV193_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEL1513150.1"
                     /translation="MIAAAKWIDDLVWGAPLLLLLLGTGIYLTSRLSLLQVIKLPKAF
                     RLIFAKNEGQGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYSEGVLAIKYRTKDANGQISGGPMYYILNGMGQKWRPLANLFAVSGILVALFGIG
                     TFAQVNAITSSLHHSLGISSPLISVLLAAVVAMIIFGGIQAIAKVAETVVPFMAIFYI
                     GASLTVIAVHYTKLLPMLVLIFKSAITPTAAIGGFAGSLVKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTKEPVEQGLISMTGTFIDTIIICTLTGLAILVTGQWTSALEGAPLT
                     QSAFASIFGHMGTYALTLSLVLFAFTTILGWSYYGERCFIFLFGTTHLSYFRLIFVIM
                     VGLGGFLKLELIWILADIVNGLMALPNLIALLALSPVVIFETRAYFKRQSTK"
     regulatory      complement(17605..17691)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            17956..20247
                     /gene="pcrA"
                     /locus_tag="TV193_000940"
     CDS             17956..20247
                     /gene="pcrA"
                     /locus_tag="TV193_000940"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEL1513151.1"
                     /translation="MNPLLDGMNDKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKYVNPWNILAITFTNKAAREMRERALALSPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRIVKALNLDPKKWSERSILATISNAKNDLLDERAYELGA
                     SDLYSQTVARCYKAYQEELRRSEAMDFDDLIMMTLRLFDQNPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVTLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDARVVL
                     LEENYRSTKKILQAANEVIQHNRHRRPKKLWTQNADGEQIVYYRANDERDEAVFVAST
                     ISNMCLELGKSFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIA
                     YLTVVANPSDNLSFERIVNEPKRGVGPGTLDKLRQFAYGQGQSLLEAASSLEQSPLKG
                     KAAQAMLALASLLSDLRADLDQLSITALAEALLEKTGYLDMLRVQNTLESQARIENIE
                     EFLSVTKSFDDLSAQQQEHEAGIDRLGRFLNDLALIADSDDGNAETAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLARAAEDQDELEEERRLAYVGITRAEECLFLTNANTRTLF
                     GKSSYNRPTRFLKEMSENLLSFQGLARPAHASFGVTFSQQGQRQFGTGMSLSEAIQSR
                     KSMAQPARAASTSTPLPFGPNAATSKQAVDWQIGDIAHHKKWGAGTVLEVKGSGKTME
                     LTISFPDVGLKKLLASVAPIEKK"
BASE COUNT         5976 a         3757 c         4673 g         6016 t
ORIGIN      
        1 acagatgata tctataaagc agcagtaaat gatgtctata taacaggcaa tacagggcaa
       61 ttatccgaaa aaatttgata atgtgctgtc aatgaagcaa gtagaagaag tattataaaa
      121 aaataaatat aagattagct aaagagaaaa ttcaagctgt tcttaaagga ttttttggcc
      181 ttttttttgc tatcactttc atagaaactt acggtaaccc acgaacagga caaaaagaaa
      241 aaaccttgat ttaacaaggt tttagtaagt tatggtaact tacggtaagt attgatggag
      301 ctggtgggag tcgaacccac gtccaaacac ctgctaacct atttgtctac aaccataggt
      361 tatgtcttac tttaacagac caaggacaca taactcaagc catcagcctg cgagtctagg
      421 gttctctttt taggtgacta gacaatcacc taaacgtagc ttgctgtttt gagacctcta
      481 ataagacaca agcaatccta tagaagtcac gccggctggt ttttaggcag ctaaagcgta
      541 agttgtgtta ttttttgcag ttatatttaa ctggcatttt tacatctgcc gatgagttgc
      601 aaaataggcc tcataatgcc tgtcgaatcc gtaacaaccc cataaaaagg cgtatgagat
      661 acttacggat gctagtatag caaaattttt ttaaaatggc aaaaaaatag cgcttatggt
      721 atgatgaagc tatgagaaat aatgagttga agccttatgt gatatggcaa aaagtgatta
      781 agctattagg aagtctggct ttagtcggat cttttttgct agccttttgg ttttacaggc
      841 ttggcatttt aaatgacagc aatgcactca aggatcttgt tcatagtcac aaggtttttg
      901 gcccccttgt ttttgtcggt gtgcaaattg ttcagattgt ttttcctatt attccaggtg
      961 gtatgacaac tattgcaggc tttttgattt ttggcccttt gctgggtttt ctttataact
     1021 atgttggtat cttcattggt agtgtgattc tgtttttact tgtgaagacc tatggtaggc
     1081 gctttatttt actgtttata gaggaacaga ccttttacaa gtatgagaga aaattagaga
     1141 tgccatatta tgagagattg tttattctct gtatgctttc tccgatttca ccagcagata
     1201 ttatggtcat gattactggg ctgacagaga tgtcgttgaa gcgttttgtg accattattt
     1261 taatcacgaa gccactatca attattggct acagctatct ttttatcttt ggaaaggatt
     1321 tgatcctatg gtttttccat taaaaaagtc taggcattgc ctgataagca gtggctagac
     1381 tttttgttat cattggatat taagcttgtt tttgatgatg aagtgagtag caacgtaaag
     1441 gataatgcct tcaactagtt gctctatgtt taaaatagat atggctgtat gatcaccgaa
     1501 atagagtagc gagtctgagc tatttgggtt gacggtgaaa aacgcatcat ttaaataagt
     1561 catgacgaca ataatgataa taactaaaat gaaataggca caaaatgcca tcaaaccacg
     1621 acgatttgaa aatagctgac caattgagat tgctagataa atcaatagta tacttgttat
     1681 ggttgacaaa agcatgtaga tgaggataga agcattttcg actaagtttt ctggcttcat
     1741 aattgtcttt agcaccttta gtagataggt aaagtcaact gttggcgcta ttaaaataaa
     1801 gataccgatt aataggttaa tgccattaaa aatactgcaa acaaaggacg ctaacagctt
     1861 ggacaagata atctgatgtg ctgttactgg tagtgtcagt gttaagtatc cctcgcgccc
     1921 aaagacattt ttgttaaagc gattaatgat gattaatagc gttgataaga atgatccggc
     1981 aatcagagaa ccaaacgtta atgagagtgt gagaggaacc attttgtttg ccagacttgt
     2041 tgttaaacca acctcgtcag gattgtttgt aagcgtattg atggtaaaag aaaggactat
     2101 cgcgatagca atgacaccgg cattaagcgc aaaataccac ttgccaattg atctaaattc
     2161 gtattttaat aattttccaa acatgcctac ctcctaaacc ttgtagatct ctctaaataa
     2221 tgaatcaatc gattgctgat gctgaactcg taaatcatca gcgtttccag aaaggcagag
     2281 cttaccattt tttaagaaaa tagcttcatc aagtacaggc tcaatgtctg agatgaggtg
     2341 agtagaaatg ataacagagg cttgctcaga gtaattatta ataatggttt taagaatata
     2401 atctcttgct gccgggtcaa cccctccgat aggctcatca aggatataga gctttgcttt
     2461 gcggctcatc acgaggataa gctgtgcctt ttccttattt ccctttgata ggtttttaaa
     2521 gcgctcttca gcatctaagt ctaaatcctt caggagactg gtcgctttat ctctgtcaaa
     2581 atcggcatag aaatcaccaa aaaagtctag catatccttg attttcatac tttcattaag
     2641 ataggtcgta tctggtaagt aagaaatgat ttttttagtt tctacagatg gtctaaagcc
     2701 gtcaataaca atgtctccct tgtctggctg taaaagtccg ttgattagct taattagtgt
     2761 agttttgccg ctaccatttg gtcctagtaa gccgataatt tttccagaag ggattgttat
     2821 ggttaaatca tcaatagcta attgtttttt gtaagatttt gagacgtggt gcagctgtaa
     2881 tagttgtgcc attagtttga tccctcctct aaaaaggtac ttaaaacagg aatgatttct
     2941 gaacgttcaa aacctatttt gatcatattg ctaataaagg acttgagctc gttgatggcc
     3001 agctctcgtc ttttgcgcgc gataagctct tggttatctg ttacaaaccg gccggcagtt
     3061 cgttgcgagt aaactatgcc ttcacgatct aattcggtaa gtgctctttg catggtgttg
     3121 ggattaacgc cggcaatttc agcatattct cggacagtcg gcagctgatc tccacttttg
     3181 atctcttggc tgacaatttg cagcatgata tgctgtgcta tctgtgcgta aataggagat
     3241 ttctcatcaa atttccaaga catactgtct cctttctttc taaaatctgc gattaatatt
     3301 tgtactaatt aaatgataca aaaaaacgat tgacttgtca agccttgtgt gtcatctcta
     3361 gttacatact ggcttgcaat gctagtggga ttcctgctga tagtggtgca gtaaagacag
     3421 atcactgcta ttaaaagctt aaaatctggg cagtaaagtc tttttcatag tataatggta
     3481 gtaagaacgc taaaggagat gtccatgttt gctcagttag atacaaaaac agtttattcc
     3541 tttatggata gtttgattga tttagaccat tattttaaac aagccaaacg attaggctat
     3601 caagccatag ggattatgga tcaggataat ctatatgggg catatcattt tattaagggc
     3661 tgtcaaaggc atgggcttca gccgatttta ggtcttgagg tggctattac agttaaagag
     3721 caggctctta cgctgaagct tgttgcgaaa aatgatacag gctatcagca gctcttaaag
     3781 ctttcgactg aaaaaatgtc tggagaccta gacctagaca cattggtgca gtatttagaa
     3841 gggatagcag ttatcgttcc ttttagtcag agcttgcgtg atttagggct tccttttgat
     3901 tacttcattg gcattgatga ggcaagcgac ttgtcaaaga tagactctac agaaagactg
     3961 attccgctta gaacggtacg ttattttgat aatgctgaga ctgagactct gcaaatgctg
     4021 catgccattc gtgataatat tagcttagca gatacggctc tagtagccaa ggatcagttt
     4081 ttagcgcctt gtcaggagat gacggctatt ttccaggaaa agtgccctga ggctttggtg
     4141 aatctcgtaa atctaacagc ttcgattgct tatcattttg atactgattt aaagcttccg
     4201 agatttaacc gcgataagcc agcaaaagaa gagctaagag aattgaccga gtctggtcta
     4261 agagaaaagc aattatggaa ggagccttac caatttcgtc tggcagagga gctggctatt
     4321 atttcagata tggggtttga tgattatttt ctcattgtct gggatttgct gcgctttgga
     4381 aggagtagag gctattatat gggcatgggg cgtggttcag cagcaggcag tctagtggct
     4441 tattcgttgc gcattactgg gattgatcct gtcaaaaaca atttattgtt tgaacgcttt
     4501 ttgaataaag aacgctacag catgcctgat attgatattg atttgcctga tatttaccgc
     4561 tcagagtttc ttcattatgt tcgagaccgg tatggtagtg agcactcagc tcagattgtt
     4621 accttttcga cttttggtcc taagcaggct gttcgtgatg tgttcaaacg ctttggtgtc
     4681 ccagaatacg agctaacaag cctaactaaa aaaattgggt tcaaggatac cctgagcact
     4741 gtttatgaga aaaatatagc cttcagacag accattaata gccgcttaga gtttcaaaag
     4801 gcatttgaga tagctaagcg cattgaaggc aatccaagac agacctctat tcacgctgct
     4861 ggtatcgtga tgagtgatga ccatctgacc aaccatattc ccttaaaaaa gggggaggat
     4921 atgatggtga ctcagtatga tgccagtgct gttgaagcta atggcttgct gaaaatggat
     4981 tttcttggtc tgagaaattt gacgcttgta cagaaaatgc aggaaaaggt ggtcaacgat
     5041 tacggtcttt caattgacat tgaagctatt aacctagagg atcctgaaac gatagccttg
     5101 tttgctaggg gtgataccaa gggcattttt caatttgaac agcatggtgc gattagcctg
     5161 ttaaaacgga tcaagccgac tagctttgag gaaattgttg cgacaaccag cttaaataga
     5221 ccgggagcaa gtgattacac gcagaatttt attaagcgcc ggcagggaca ggaaaacatt
     5281 gatctaatag atccggtgat tgctccgata ttagagccaa cctatggtat catgctttat
     5341 caggagcagg ttatgcagat tgctcaagtt tatgcaggct ttacacttgg aaaggccgat
     5401 ttgctacggc gtgctatgtc taagaaaaac ctcgttgaga tgcaaagaat gcaggaggat
     5461 tttctgactg gtgctagagc cttgggtcgc tctgaggaga cagccagact attgtttgca
     5521 cgtatggaaa aatttgcagg ctacggcttt aaccgcagcc atgcctttgc ttatgctgcc
     5581 ctagcctttc agctagccta ttttaaagcg cactatcctg aggtattttt tgatgtcatg
     5641 atgaattatt ctagcagtga ttacatcaca gatgcgttag attttggctt tgaggccgcg
     5701 caggtgacga taaacaccat tcccttcaat gataagattg agcgtcataa gatttatatg
     5761 ggcttaaaaa acatcaaggg tcttcctaga gaattttcgt attggatcat tgaaaatagg
     5821 ccctttacca gtgttgaaag ctttttgtgc agcattcctg aaaaatacca gaaaaccagc
     5881 ttcttagagc cccttatcaa aataggcctg tttgatgggt ttgaaaaaaa tcgccaaaaa
     5941 atcattaaca acttagaagg actgctaacc tttgtcaatg aattgggatc actttttgcg
     6001 gattcctcct ttagctgggt agagactgag gattattcag ctgctgagaa atattacttt
     6061 gagcaggatt tgcttggtgt tggcatgagc aagcacccct tgctagctgt cgctgaaaaa
     6121 agcacagtag cagtcacacc aatcacaaag ttagtgaagg atacagaagc tactttgctg
     6181 gttcaaatag atgcgatcag ggttattcgg acaaaatcaa gcggacagca gatggccttt
     6241 ttgagtgtta ctgataccaa acagaaatta gatgttaccc tttttcctga gcaatatgct
     6301 gtctataagc aagacctaaa agaggggcat atttactata tcaatggcag ggtaaaagaa
     6361 agagataacc gcttgcagct agtctgtcac cagcttcgat tagctcagag tcaaaggtat
     6421 tggctattgg ttgaaaacca tcagcatgat gctgctattt ctgacatatt aacagccttt
     6481 tcaggggaga ctcctgttat tatccattat caagaaggca aagaaacctt agagttaaac
     6541 catattaggg ttgatgttag taaggatttg gaggaggcta ttagccccta cgtgttgaaa
     6601 acggtttttc gataaaaata gcgaattagt gaagtaattt gcaaacgaat gtgctataat
     6661 aaaaacgtta aattaattaa aggagtacca aaaaatgaaa cgtattgctg ttttaaccag
     6721 tggtggtgac gcccctggta tgaatgctgc tattcgtgca gttgttcgta aagcaatttc
     6781 agaaggaatg gaagtctatg gtattaaccg cggctatgct ggtatggttg atggtgatat
     6841 ctttccacta ggctcaaaag aggttggtga taagatttct cgcggcggga ccttccttta
     6901 ttcagctcgc tacccagagt ttgctcagct tgaggggcaa ttggctggta ttgagcagct
     6961 aaaaaagcat ggcattgaag gggtagttgt cattggtggt gatggttctt accatggtgc
     7021 gatgcgcttg actgagcatg gcttccctgc agtaggtatc ccagggacga ttgataacga
     7081 tattgctgga acagactata ctatcggatt tgacactgcg gtcaatactg cggtagaggc
     7141 tattgataag cttcgcgata cctcatcaag tcatggacgg acctttgttg ttgaagtgat
     7201 gggacgcaat gcaggtgata tcgcactttg ggcaggtatt gcaagtggag cagatcaaat
     7261 catcgttcct gaagaggaat ttgacattca taaagtggtc tcaacaatta aagacgattt
     7321 tgaaaataga ggaaaaaatc accatattat cgttttagct gagggtgtta tgagtggcga
     7381 ggcctttgcg cagcagctaa aagaagctgg agatgaaagt gaccttcgtg tgacaaacct
     7441 tggtcatatc cttcgcggtg gctctccaac tgcgcgtgat cgtgtgattg cgtcatggat
     7501 gggagcgcac gctgttgagt tgctcaagga aggcaaaggt ggcttggctg ttggtattca
     7561 taatgaagag cttgttgaaa gtccgattct tggaagtgca gaggacggtg ccttgttcag
     7621 ccttactgat gagggtaaca ttgttgttaa taacccgcac aaggctcgct tagactatgc
     7681 tgctttgaac cgttcattag cacaatagga taagtaagat ctggtaatct ttgttaatca
     7741 actaaaaaat aagggagttt cataataaaa tgaataaacg tgtaaaaatt gttgcaacac
     7801 ttggtcctgc ggttgaaatt cgcggtgcta aaaaatatgg tgaggacggc tattgggctg
     7861 gtcagttgga cgttgaacaa tcagctaaaa agatcgctga attgattgaa gcaggtgcta
     7921 atgttttccg ctttaacttc tcacatggtg accacaaaga gcagggtgac cgtatggcta
     7981 ctgttcgtct tgctgaaaag ctggcacgtc aaaaggttgg tttccttttg gatacaaaag
     8041 gaccagaaat gcgtacagaa ttgtttgctg acgatgccaa agaatatagc tatgtgactg
     8101 gtgagcgtat tcgtgttgcg acagcacaag gcattcaatc aactcgtgat atgattgcct
     8161 tgaatgtagc tggtgctctt gatatttatg atgaggttga ggttggccac actattctta
     8221 ttgacgatgg aaagcttggc ttaaaggtta tcgagaagga cattgcaaag cgtgagttca
     8281 tcgttgaggt tgaaaatgat ggcatcattg caaagcaaaa gggtgttaat atccctaata
     8341 ccaagattcc tttcccagcc ttagcagaac gtgataatgc tgatattcgt tttggtcttg
     8401 agcaaggtct taactttatt gctatttcat ttgttcgtac tgccaaggac gttgaagagg
     8461 ttcgtgagat ttgtcgtgaa acaggcaatg agcatgttca attatttgct aaaatcgaaa
     8521 accaacaagg tattgataac cttgatgaaa tcatcgaagc tgcagatggt atcatgattg
     8581 ctcgtggtga tatggggatt gaggtgccat ttgaaatggt tccagtcttc caaaaaatga
     8641 ttatcaccaa ggtaaatgca gcaggtaaag cagtcatcac cgcaactaac atgcttgaaa
     8701 caatgactga aaaaccacgt gcaactcgtt cagaggtatc tgacgttttc aacgcggtta
     8761 ttgacggtac agatgcgaca atgctttctg gtgaatcagc aaatggtaaa taccctgttg
     8821 aagcagttcg tacaatggct acaattgata aaaatgcaca aactcttctt aatgagtatg
     8881 gtcgtttaga ttcatctgcc ttcccacgta ccaataaaac tgacgtgatt gcttcagctg
     8941 ttaaagatgc aacacactca atggatatca agcttgttgt gaccatcact gaaacaggaa
     9001 acacagctcg tgccatttct aagttccgtc ctgatgctga catcttggct gtgacctttg
     9061 atgaaaaggt tcaacgtgcc ttgatgatta actggggtgt gattccagtg cttgctgaaa
     9121 gaccagcatc aacagatgat atgtttgagg tagcagagcg tgtagctctt gagactggtt
     9181 tggtgcaatc aggagataat atcgttattg ttgcaggtgt gccagttggt acaggtggta
     9241 caaatacaat gcgtgttcgc actgtaaaat aatagctttc cataagcttt agctattttg
     9301 ctctatcaga taatttaagg caaacaatga tacttaaaaa ttgtttgctt tttttattag
     9361 tcatatcatg ttataatgag actatagact aggagttatt atggtaaagc gagattttat
     9421 aagaaatata ttgttgttat tgattcttat tgtgggagct gtccttctta gaatatttgt
     9481 tttttcgacc tatcgagtca cgtcagaggc ttcaaatgcc tatttgaata agggcgattt
     9541 aatcaccatt aagaaaaata ttgagcctaa atataaggat tttgtggttt atacggttga
     9601 caaaaaggat tatgtgagcc gggttgtagc agtagcaggt gatcgtgtta cctatatgga
     9661 cgatattttt tacctgaaca atatggttga atcccaatcc taccttgaga gtatgaaggc
     9721 aaagtatctc aatcatgccc ctattggtac gctttatacg gaggatttta cgatttcgac
     9781 ggttacttct ggaaaatacg atagcattcc caaggggaaa taccttttgc taaatgataa
     9841 cagaaaaaac catcatgata gccgtcagtt tggcttaatt gacgtgtcac aaattaaggg
     9901 attagtaaca tttagagtgc ttcctttgaa agactttgga tttgtagagg tagagtagct
     9961 ttaaggctgc tctattttgt ttctcaaaat atgactatac caattttctt gttgacaaga
    10021 tttttctgaa gttatatact ctaaatataa cgttttagtc ggtttatatc tgactatacc
    10081 aattatattg atcattaaag aaagtagtaa gctagcttac tgaggtgtta agttatgtgt
    10141 ggaattgttg gagttgtagg tagtcgtaat gcgactgaca tcttgatgca gggattggaa
    10201 aaattagagt atcgtggtta tgattcagct ggtatttttg tgtcagatgg caggacgtcc
    10261 aatttggtaa aatctgttgg acgcattgca gatttacgct ctaagattgg cattgatgtt
    10321 gttggaacga ccggtattgg tcatacacgt tgggcaacgc atggtcaagc aacagaggaa
    10381 aatgctcacc ctcatacctc tcagacaggt cgctttgttc ttgttcataa tggtgtgatt
    10441 gaaaattacc tccagatgaa ggagcagtac cttgctggac acacgtttaa aggacaaaca
    10501 gacaccgaaa ttgcagttca tttgattgga gcatttgttg aagaaggctg ttcagtctta
    10561 gaggctttta aaaaggcttt atcaatcatt gaaggctcct atgcctttgc tttgattgat
    10621 acagaggata tggatacgat ctatgtcgct aagaataaat ccccattgct gattggcctt
    10681 ggtgagggct ataacatggt ttgttcagac gctatggcca tgattcgtga aaccagcgaa
    10741 tttatggaaa tccatgacaa ggagctggtt atcctgacaa aggattcagc aagggtgaca
    10801 gattatgctg gcaatccgat tgatcgtcag tcatatacag cagagcttga tctttcagat
    10861 attggcaagg ggacctatcc attttatatg ctaaaggaaa ttgacgagca gccaacagtg
    10921 atgcgtcgct tgatttcaac ctatgcagac gccaagggac agatgatgat tgatccagct
    10981 atcataaggt ctgtccaaga ggctgatcgt atctatattc ttgcagctgg gacctcttat
    11041 catgctggct ttgcttctaa gtcaatgctg gagcatttga ctgatacacc tgttgaatta
    11101 ggggttgctt ctgagtgggg ctacaatatg ccgctattga gcaaaaagcc aatgtttatc
    11161 ctcttgagcc agtccggtga gacagcagat agccgtcagg ttttggtcaa ggcaaatgag
    11221 atggggattc caagcctaac agtgacaaat gttcctggct caaccctatc acgtgaagca
    11281 acctacacta tgctgctcca tgcaggtcca gaaattgcag ttgcatcaac taaagcctac
    11341 acagcacagg tcgctgcact tgcctttcta gctaaggcag ttggtgaggc taatggcaag
    11401 aaggaagcta ttagctttga tttggttcat gaattgtcat tggtcgctca gtctattgag
    11461 gccaccttat ctgacaagga gctgattgct gagaaggtgc agaccttatt ggcaacaaca
    11521 cgcaatgcgt tttacattgg tcgtggcaat gattattatg ttgctatgga ggctgcacta
    11581 aaattaaaag aaatttcata cattcagtgt gaagggtttg cagctggtga gctaaagcat
    11641 gggactattt cactgattga ggatggcaca cctgttattg gacttatttc ttcaagtgag
    11701 ctggttgctg cacatacacg tggcaatatc caagaggtgg ctgcacgtgg cgctcatgtg
    11761 ttgacagttg ttgaggaggg cttagagcgt gagggagatg acattattat taataaggtg
    11821 cacccattct tagcgccgat tgctatggtt attccgactc aattaattgc ttactatgct
    11881 tccttgcagc gtggtttaga tgtagataag cctcgtaatt tagccaaggc tgttacagtt
    11941 gagtaatagt tgcctgctta aaatgaggca gcagggtcct gaagcctatt tgaaacgagc
    12001 ttgacatgat gttatgtcag gctcgttttt tagtgcttgc ctggtcttat gataacgtat
    12061 tcatcttgtc aaataagcat ttctgaagta aaatattaac gttaagacta agaagcttag
    12121 gagagtaaga tgacgttacc aaattgttta caatgcgatt cagaatatgt ttatgaggac
    12181 gggcatttgc tcatttgtcc gatgtgttcc tttgaatgga cacgtggtga ggaggagcct
    12241 gaggaggagg ggcttgtcgt tttagatagt aatggaacta gattagctga tggagacact
    12301 gttacgatca ttaaggacct gaaggtcaag ggagcgccga aggatctcaa gcagggaact
    12361 cgtgttaagc atattcgtct tgttgaaggt gatcacaata ttgattgtaa gattgatggc
    12421 tttggtgcaa tgaagctaaa atcagaattc gtcaagaaga tttaataaca ataagcaacc
    12481 agatgactgg ttgtattttt atagaaaagt acttttcaat ccatcagaaa atttggtata
    12541 atggataaac tatttatatc taggagacaa catgacgtat attatgcagg ttttacccag
    12601 cttgctggat ggtgccttaa tcactttaca ggttttcttt attgtaattg tattatccat
    12661 tcccttaggg gctcttttag cttttttgat gagggttgac tttaagccct tgcagtggct
    12721 attgacgctc tatatttggg tcatgagggg aacaccctta ttgttacagc tcatcttttt
    12781 ttattatgtt ttgccaagtg tgggtgttac ctttgatcgt atgccggcag cgattttggc
    12841 ttttacctta aactatgctg cttattttgc cgagattttt cgtggcggga tagagactat
    12901 tccaaatggg caatatgagg ctgcaaaggt gctgaagctt agtccggtac aaactgttcg
    12961 ctatgttatc ttgcctcagg tgttcaagat tgttttacca agtgttttca atgaggtgat
    13021 taacttagtt aaggattctt ccttggtata tgtgttagga gtaggggatt tgctattagc
    13081 aagcaagact gcggcaaata gagatgcaac cttagcaccg atgtttattg caggtttgat
    13141 ttatttgctc ttaattggtt tggtcaccat tttatcgaag caggttgaaa aaagatttaa
    13201 ttattatcag taagggggtc atatgttaga actgaacaat atttcaaagc gatttggtca
    13261 caagcagatc tttgatggct ttcatttgac cgttgaagat ggtgaggttt tatctttggt
    13321 agggccatct ggtggtggca agactactct gctccgaatg ctggctggct tagagcctat
    13381 tgattcggga aatattagct ataatggcga gtctgttcct attgatcatt tagaaaaaag
    13441 aagcctgctt ggttttgttt ttcaggattt ccaattgttt ccacatttga cggtgctgga
    13501 taatctcatc ttgtctccta ccattaccat ggctatgcca aggcctgatg caaagcaaaa
    13561 ggctatggag ctgctggagc gcctaggtct caaagagcat gcagctgctt atccttatgc
    13621 gctatctggt gggcaaaagc aaagagttgc cttggctaga gcgatgatga ttgacccaca
    13681 gattgtaggc tatgatgagc cgacaagtgc cttagactct gaattacgtc aggaggttga
    13741 gaaattgatt ttgcaaaatc gtgagatggg cattacccag attgttgtca cccatgattt
    13801 gcagtttgct cagaccattt ctgatcgtat catcaagatc aatcctaaat agaagaagag
    13861 gtagtgctat gacgttaaaa aagacccttc tagtagccct atttgctgct acagctacgc
    13921 ttttagtagc ttgtggcgct agtaataaac agactagctc agatgcttgg gattcctaca
    13981 agcagaaaaa gacgattacg cttggctttg ataatacttt tgtgccaatg ggctataagg
    14041 acgagtcagg aaaaaatacc ggctttgata ttgagctagc aaaggctgtt tttgaccaat
    14101 atggtatcaa tgttaagtat caagccatta actgggatct caaagaaact gagttgaaca
    14161 atggtaaaat tgacctgatt tggaatggct attctgtgac aaaagagcgc caagctaagg
    14221 tggcctttac agagccttat atgaaaaatg agcaagtctt agtgacgcaa aaatcatcgc
    14281 aaataagctc atttgctgat atgaaaaata agaccttagg tgcccagtct ggctcatctg
    14341 gctatgatgc ctttacgagt catcctaagg tgctaaagga tcttgtcaag ggaaatgacg
    14401 ctacccaata tgaaaccttt acacaagcct ttatcgattt aaaaaacaag cgtattgatg
    14461 gccttttgat tgatagggtt tatgccaatt attaccttca gcaagaaggt gagctagacc
    14521 gctataacat tatcgcgagt gagtttgaag gtgaggattt tgcagttggt gtccgaaaag
    14581 cggataaaac cctacaaaaa aagattacac aagccttaaa atcgctttat caggacggta
    14641 ccttccaaaa aatctctaaa aaatggtttg gtgaagatgt cgcaacagtt cagttgaaat
    14701 cataagacgc aagcaagacc taatcagctc agaggggttg agactagata catttaaaag
    14761 acttaccttc taaaggcaag tctttttata cggcttatta ttagctgata cgcttgatat
    14821 gatagtgttt tttaattgct atggagtttg ttattggtgt gatttgatga tatatcaggt
    14881 gccaagcttc gtgtcgtctc cagatactgg tatgctgatt gccctgtagc tgataggtga
    14941 ctagcttggt gttgtggctg atggattgca tacaaaaggc ttcaagctga ttggaagaag
    15001 aacgctgctg ctctaaaaat tgcttggcat tgtaagcttg tccatcgcga tcaataaagg
    15061 taaaggtctt ggcaatgagc tcttgataat ctgggatttg acttagcatg attttctcgt
    15121 ttttgtagag ctttttgtaa acatattcac agttgtcatc tttaggaagc tttgcaggct
    15181 caacatgaat atcaatatca taaacagcaa attgctcact caagagctgt tcgacctgct
    15241 cggttatggc gtgactttca taaacagaaa ggtcagggtg catctcaagg acaatatcta
    15301 aatagacatt gcttccgtaa gtgcggccgc gctgtgattt gacagcaatg attttgggaa
    15361 ttttcaatat ggccttttca tatgctttga gctgcgtgct gtcaaagcca tctgataagc
    15421 taaaggcgct tgccataaaa atatcaaagg ctgtttttag aatgaaaaag gtaatgataa
    15481 gggcagccag cctatcaata ataggtagct ttaaggaagc ggcgataata gcaatagagg
    15541 ttccaataga ggtcacagca tcagaaagat tatctttaga ggctgcaacc aaggcactgg
    15601 atcttacctt ttttgataac gctttattaa aagcatatac tccaagcatc acaagggctg
    15661 aagcgatccc aacaatagca cctaatggat cgatagcaga ctgcttacca ctaatcatct
    15721 gttgaatagt ttgcaggaga acctgaaagc caacaatgaa catgataaag gaggttatta
    15781 agcttgaaag gtcttcgatt ttccagtggc caaagcggtg attggcgtct gctggctggc
    15841 tggccagatg aagtccgatg agcagagtga cattaccaac gatatcagac aggttgttga
    15901 agccatcggc aatcaaggag ctggcattta aaagatagcc agcaagaagc tttgtgatgc
    15961 taagggccaa ataggtaaca atgctaacaa tgggccctct ttttgctaac cgaaggtttt
    16021 ctactggatt gtttggcata aaaactcctt tgtaactgat gctttcatta tatcataaaa
    16081 gctaagacaa gctaaaagcc tagagctatc ctaaataggg tattccaggc ttttcgatag
    16141 cttatttggt gctttggcgc ttaaaatatg cccttgtctc aaaaatgaca acaggagata
    16201 aggctagtag ggcgataaga tttggcagag ccatcaggcc attgacaata tctgccagta
    16261 tccaaatcaa ctccagctta agaaagccac caagtcctac catgataaca aagatcaggc
    16321 gaaaatagct gaggtgtgtc gtgccaaata aaaagataaa gcagcgctca ccataatagc
    16381 tccagccgag aatagtcgta aaagcaaaaa gaacaagcga cagggtcaag gcataggtgc
    16441 ccatatgccc aaagatagaa gcaaaggcag actgtgttaa gggtgctccc tctagtgcgc
    16501 tagtccactg accagttacc aaaatggcca gaccagtcag agtgcagatg atgatcgtgt
    16561 caataaaggt tccggtcata gaaatcaggc cctgttctac tggctccttg gttttagcgg
    16621 cagcagcagc gatcggagca gagcctagtc ctgattcgtt agaaaaaacc ccacgtgcaa
    16681 tacccttttg aatggcgtcc ttaaccaagc ttccggcaaa gccccctata gctgctgtag
    16741 gggtaatagc ggacttaaag ataaggacaa gcataggaag aagcttagta tagtgaacag
    16801 caataaccgt taagcttgct ccaatataaa agatagccat gaaaggaacg actgtttcag
    16861 ccaccttggc aatagcttga atgcctccaa aaataatcat ggccacaaca gcagctagca
    16921 agacactgat taatggcgaa gagatcccaa ggctatggtg tagggatgag gtaatcgcat
    16981 tgacctgagc aaatgtcccg attccaaaca aagccactaa aataccagag acagcaaata
    17041 agttggctag aggcctccat ttttgcccca taccatttaa aatgtagtac ataggtccgc
    17101 ctgaaatctg accattagcg tccttagtac ggtatttaat ggctaaaacg ccctcggaat
    17161 atttggttgc cataccaaag aaggcagcaa cccacatcca aaaaagtgcc ccaggtccac
    17221 cagactttat agcggttgcg acaccaacaa tattaccagt accaactgta gcagctaggg
    17281 ctgttgctag agcagcaaat gatgaaatat ctccttgccc ctcattctta gcaaaaatga
    17341 gcctaaaggc cttaggcaac ttgatgactt ggagaaggct aagtctgctg gtgaggtaaa
    17401 tgccagtacc aagcagcagt agcaacaagg gtgctcccca aaccaaatcg tctatccatt
    17461 ttgcagcagc tatcatgctt aattcctcaa ctctcttaac caatgctgcc aaaagaaaaa
    17521 gccacccctg cggatagcct ctgaagcata tgacaaaaca gcaagcacaa aaaatgctaa
    17581 ggaagcatga tcatacggct tgatatttta tcttctgtcc ttttgcctga gagattgagc
    17641 agtcttgcct tgccccttcg gcgcctaata ggtctctcca gaagcccgtc cgtcaagcag
    17701 tcccgtccaa cacctgaaca cctgagagta taactccttc ggcgaaatcc attcttctcc
    17761 tgcatgacat cattcggttt attaaattat gtctatgata cccaaaaagc ctagtgatgt
    17821 caacaagcaa tttaactgat ggctaactcc ttgtttttat ggtaacatca ttgtcctctt
    17881 ttttcttttt gactgaaaca tgatataatc gtaaggttaa taaaagtcac ttattagacg
    17941 atatgaggag aaagcatgaa tcctttatta gatggaatga atgataaaca agcagaggca
    18001 gttcaaacga ctgagggccc cttgttaatt atggctggtg ccggttctgg gaaaacgagg
    18061 gtattaaccc accgcattgc ctacttgatt gatgaaaagt atgttaatcc ctggaatatt
    18121 ttggcgatta cctttactaa taaggctgcg cgtgagatgc gagaaagggc attggcctta
    18181 agcccagcca ccaaggatac cttgattgcg acctttcact caatgtgtgt tcgtatttta
    18241 cgccgtgagg cagatcatat tggctacaat cggaatttca cgattgttga tccaggagaa
    18301 cagcggacct taatgaagag aatagtaaaa gctctaaatc tggatcctaa gaaatggagc
    18361 gagcggtcga ttttagccac catttcaaat gctaaaaatg atctcttaga tgaaagagcc
    18421 tatgagctag gagcctctga tttgtatagc cagacagttg cccgctgcta caaggcctat
    18481 caggaggagc tcagacgaag tgaggctatg gattttgatg atttgattat gatgacctta
    18541 cgcctatttg atcaaaatcc tgacgttcta gcctattatc agcagcgtta tcaatatata
    18601 catgtcgatg aataccaaga cacaaaccac gctcaatatc agctagtgac tcttttagcc
    18661 tcacgcttta aaaatatttg tgttgtcggt gatgcagacc agtccattta tggctggcgt
    18721 ggtgctgata tgcaaaatat tttagatttt gaaaaggatt accctgatgc aagggtggtt
    18781 ttgctggaag aaaattatcg ctccaccaag aaaatccttc aggcagctaa cgaggtgatt
    18841 cagcataatc gtcatcgtcg tccgaaaaaa ttgtggactc aaaacgcaga cggtgagcag
    18901 attgtttatt atagggcaaa tgatgagcgt gacgaggctg tttttgttgc ctcaaccatc
    18961 agcaatatgt gtctagagct aggaaagagc tttaaagact ttgctgtttt atatcgtacc
    19021 aatgctcagt cccgtacgat tgaagaagcc ttgttaaaat caaatattcc ctacacgatg
    19081 gtcggaggaa ccaaattcta cagcagaaag gaaattcgtg atgtgattgc ctatttgact
    19141 gtggttgcta atccgtcaga taatctctcc tttgaacgaa ttgtgaatga gcctaaacga
    19201 ggggtagggc caggaaccct agataagctc cgccaatttg cttatgggca aggacagtca
    19261 ttgttagagg ccgcttcaag ccttgagcaa tcaccgctaa aaggaaaggc tgcccaagcc
    19321 atgctggcct tagcgagtct cttaagtgat ttgagagctg atttagacca gctgagcatt
    19381 acagccctgg ccgaggcctt gctggagaaa accggctatc tggatatgct gcgcgtccaa
    19441 aataccttag aaagtcaagc taggattgaa aatattgaag aattcctgtc tgttaccaaa
    19501 agctttgatg acctatcagc acagcagcag gagcatgaag caggtattga tcgcttagga
    19561 agatttctca atgaccttgc tttgattgct gatagtgatg atggcaatgc agaaaccgct
    19621 gaggtaactt tgatgactct gcatgcagct aaggggctag aatttcctgt tgtttttctc
    19681 ataggtatgg aggagggagt ctttccttta gcccgagcag ccgaggatca agatgagcta
    19741 gaagaagaaa ggcgactagc ctatgttggc attaccagag ccgaggaatg cttgttttta
    19801 acgaatgcca atacacgtac cctatttggt aaaagcagct ataatcgccc aacaaggttt
    19861 ttaaaagaga tgtcagagaa ccttttaagc ttccaaggct tggcaagacc tgctcatgct
    19921 tcctttggtg tgacattttc gcagcagggt caacgacaat ttggcacagg aatgagtcta
    19981 tcagaggcta tccagtccag aaaatcaatg gcacagcctg ccagagcagc ctcaacatct
    20041 acaccgctgc cctttggacc gaatgcagct acttcaaagc aagccgttga ttggcagatt
    20101 ggtgatattg cccatcataa aaaatggggt gctggaacgg ttttagaggt caagggatct
    20161 ggtaagacca tggaattaac cattagtttt cctgatgtcg gattaaaaaa actccttgcc
    20221 agcgttgctc ctattgaaaa aaaataaaag gtacagctta tgggcaattt gcatagtcac
    20281 ttggataagg gctttgcaat tgcggtttag ttctgcgatt taagaaaaga agtaagcaag
    20341 gattttatca gttaaccaca taccaagctt ttgatggcct tgatgccgga gagagcttgg
    20401 tattttttta tttttaaaaa aa
//
LOCUS       DARYXS010000032        19591 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.032, whole genome shotgun sequence.
ACCESSION   DARYXS010000032 DARYXS010000000
VERSION     DARYXS010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19591
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.032"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(169..639)
                     /locus_tag="TV193_000941"
                     /pseudo
     CDS             complement(169..639)
                     /locus_tag="TV193_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            854..1075
                     /locus_tag="TV193_000942"
     CDS             854..1075
                     /locus_tag="TV193_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1513152.1"
                     /translation="MDTKFTALTEEQLKSVEGGKNGVVKLPGGTGVYCWNTGKNSAKC
                     GMDWSVAGPYVGKIIVNGWVNHGPWASRP"
     gene            1105..1398
                     /locus_tag="TV193_000943"
     CDS             1105..1398
                     /locus_tag="TV193_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1513153.1"
                     /translation="MNERDLVQLIEQTLKDEEVQNNVTYRNLLEESLQQLSLKKPVYL
                     VSTRLAGHISTYLMTNHYEAPKAIIVLAQSIASTPAKHRGLISIPFWLSNIFR"
     gene            2535..4367
                     /gene="lepA"
                     /locus_tag="TV193_000944"
     CDS             2535..4367
                     /gene="lepA"
                     /locus_tag="TV193_000944"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEL1513154.1"
                     /translation="MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQ
                     VRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVAD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNITDGDMLE
                     VSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFI
                     VHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK"
     gene            4909..5346
                     /gene="msrB"
                     /locus_tag="TV193_000945"
     CDS             4909..5346
                     /gene="msrB"
                     /locus_tag="TV193_000945"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1513155.1"
                     /translation="MESKEELRQRIGDLAFEVTQHAATERAFTGQYDDFFEKGIYVDV
                     VSGEVLFSSLDKFNSGCGWPAFSKPIQHRMVTNHHDSSHGMRRVEVKSREAGSHLGHV
                     FNDGPKEAGGLRYCINSAALKFIPYDQMEQEGYAEWLGIFDKS"
     gene            5634..6653
                     /locus_tag="TV193_000946"
     CDS             5634..6653
                     /locus_tag="TV193_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEL1513156.1"
                     /translation="MLTSLEKLPGVLLCLLLALPAWYLGSLFPIIGAPVFAILLGMLL
                     ALVYQKRDYTKSGIALTSKYILQLAVVFLGFGLNVTQVLVVGLQSLPIIVVTIVTALG
                     ISYLFKRWLRLPAKTAILVGVGSSICGGSAIAATAPVIDAQDDDIAKAISVIFLFNIL
                     AALLFPALGQMLGLSNHGFAIFAGTAVNDTSSVTATATAWDAIHQSNTLDGATIVKLT
                     RTLAIIPITLGLSIYQTKSRQAHTTEGSFSLRKAFPTFIVFFLLASLITTFAASLGLP
                     MAIFHQLKLLSKFFIVMAMAAIGLNTNLVTLVKTGGKAILLGGICWLAITSVSLAMQA
                     ALGSW"
     gene            6997..7422
                     /locus_tag="TV193_000947"
     CDS             6997..7422
                     /locus_tag="TV193_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEL1513157.1"
                     /translation="MKRKFLIGSHGRMASGLKSSIDILAGRGQELQVIDAYIDDSDYT
                     EQVLTFIEDVAADEQALIFTDLLGGSVNQKIVTALMDSGKENIFLISNSNLAALLSLM
                     FLKPEEELTKDEIVATINDSQVQLVDLAPATAAEDDFFN"
     gene            7437..7928
                     /locus_tag="TV193_000948"
     CDS             7437..7928
                     /locus_tag="TV193_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1513158.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKVFNDPRAVDKRIFVIVSSIKDACQIAKQVKDLEAVN
                     VANVGRFDKSDPATKVKLASSLLLNPAELEAAKELVSLPNLDVFNQVLPSNSKVSLSQ
                     LIK"
     gene            7946..8755
                     /locus_tag="TV193_000949"
     CDS             7946..8755
                     /locus_tag="TV193_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1513159.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIVYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFFLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITKGAISNQSSFDSKESEEEDFFA"
     gene            8752..9579
                     /locus_tag="TV193_000950"
     CDS             8752..9579
                     /locus_tag="TV193_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1513160.1"
                     /translation="MRSQDNLTKEERKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINLFYKTDKDKADALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPTFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASTGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGSMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQNYLDQLFIGVVPLLVTMTAFWLLRKKVNINWIMFGIMLLGIVLGLLGIC"
     gene            9769..11403
                     /locus_tag="TV193_000951"
     CDS             9769..11403
                     /locus_tag="TV193_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1513161.1"
                     /translation="MEERFKKRLQDDISHHFSHQSLILSILLIGLFLIFSLAPQQIGL
                     YQDLKAVEHSYHQLIRQNKALLTELNQHILTKFVNHQLSSSDLSKQYYHLRNRSQSQS
                     ELLVFDANSHMLFASNQHLGNFFRNAVYMTEVLKKARQRSSFLRISMDNEEGHYLLLI
                     KPIKIDHQVKGYSLLVMNGKDFLQLSHQIASDFVIADQFDNSFAFTNRTFMTSSLNKL
                     DSHFLKGYFIFHEHRAFILRKVALSPSITLYSYRPLIPVSIALLFSLMSSVMIYAILY
                     WKSKALATQIASSNSAAINQMILDMQAISRQEKNAIDLQSQDEFQYLSVQINQMISRL
                     QALHQKTLALEKQNVSFEKRMLEAQFNPHFLYNTLETILITSHYDSDLTEKIVLQLTR
                     LLRYSLDESQEAVCLGEDLAVLESYLLISQIRFEELRYTIAVEPALETLRVPKLFLLP
                     LIENAIKYGLRYRHDLVIEISVRQLADGIYFTVADNGPGISQKRQADIKELLHSEDSH
                     HGLVNSYRRLKHQFIKVELIFCQRDERFLLTYMVKE"
     gene            11407..12192
                     /locus_tag="TV193_000952"
     CDS             11407..12192
                     /locus_tag="TV193_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1513162.1"
                     /translation="MYKLLIVEDEHIIRKWLRYAIDYHALNILVIGEAKDGQQGAKLI
                     AEAKPDIVLTDINMPIMTAFEMFEATKEQSYAKIILSGYADFANAKSAIHYGVLEFLT
                     KPLERQALHDCLLTIIQKLQQQSQEQELSQQQDYLKLPQPNDQLPDVVQEMLSWIHEH
                     YQDKIMIGQLAHDLGYSESHLYHLAKKYLKMTFSDYINQYRLNRAIQLLIAEPDVMVY
                     QLAEAVGIYDYRYFDRVFKKYLGQTVKDFRETVLHQRSDRSSL"
     gene            12216..13226
                     /locus_tag="TV193_000953"
     CDS             12216..13226
                     /locus_tag="TV193_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1513163.1"
                     /translation="MAIVILGVIGSGLYAIWRHQAGPAPSKPRELVVLTPNSQNILTG
                     TIPAFEEKYGIKIRLIQGGTGQLIDRLQKDKDQLHADIFFGGNYTQFESHKELFEPYL
                     SKHIGFVLPDYLLQSEVATPYTLNGSVLIVNNELAKDMVITSYEDLLKPELKGKIAFA
                     DPNTSSSAFSQLTNILLAKGGYTNPKAWSYIKQLIHSMNSIKSASSSDVYQSVAEGKM
                     TVGLTYEDPCVNLLKSGANVSIVYPKEGTVFLPSAVAIVKQSKAKADAKLFINYMLSL
                     DVQRAFGQSTSNRPIRKDAKASQDMKPLDDIITLKEDYDYITRHKKDILERYNQLRKT
                     TD"
     gene            13479..15263
                     /gene="uvrC"
                     /locus_tag="TV193_000954"
     CDS             13479..15263
                     /gene="uvrC"
                     /locus_tag="TV193_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEL1513164.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKAGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTGSNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNEPFPRLLITRQIKKNDGLYFGPYPDAYTATEVKKLLDRIFPFKKCKNPVNKVCF
                     YYHLGQCQAHTICHTDKAYWDSLVADVKQFLNGKDDKIIDDLRSKMLEASHNQEFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNM
                     FPYYNEAEEDFLTYVGQFYSDQRHLIPKEVFIPETIDETLVAAIVPARIVKPQRGEKK
                     QLVALATKNARVSLQQKFDLLEKDLRKTSGAIEHLGQLLGIEKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVKHEGLQAPDLI
                     IVDGGQGQVKAARDVIEHQLGLSIPVAGLQKNDKHQTHELLFGNPLAVVELPRNSEEF
                     FLLHRIQDEVHRFAITFHRQVRSKNAFSSKLDHIAGLGPKRKQLLLKRFKSMTALEQA
                     SLEEIQQLGIPKTVAEALFDHLTSKSEV"
     gene            15391..15993
                     /locus_tag="TV193_000955"
     CDS             15391..15993
                     /locus_tag="TV193_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEL1513165.1"
                     /translation="MKFLELNKKRHAIKRFNDKPVDYNDLRTAIEVATLAPSANNIQP
                     WKFVIVEEKKAELAKDLPLANKTQVEQAQYVIALFSDTDLIQRSRKIARIGVKSLPDN
                     LIGYYMETLPPRFATFTETQKGEYLAINAGLVAMNLVLALTDQKMASNIILGFNKKLT
                     NEILDIDPRFRPELLITVGYSDDKPEPSYRLPVDEIIERR"
     gene            16074..17483
                     /gene="pepV"
                     /locus_tag="TV193_000956"
     CDS             16074..17483
                     /gene="pepV"
                     /locus_tag="TV193_000956"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEL1513166.1"
                     /translation="MTTIDFKAEVDKRKEAMLEDLSNLLSINSERDDAKADAKHPFGP
                     GPVKALEFFLAMAERDGYQTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWETDP
                     YKPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKRVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFVGQNAGAFVLHRFQGGLREN
                     MVPESATALISSPHELNVIEASLEQFLSEHAVTGSVKEADGLLEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFSFDGAAKAYLHIAGEVLHEDFTAEKLGLAYTDDKMGALSMNA
                     GVFSFAKDSDDNTIALNFRYPKGTNAAVLKAGLEQLPGLTKVTLSEHEHTPHYVPMDD
                     ELVSTLLSVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     DNIYRSAAIYAEAIYELIK"
     gene            complement(17750..19126)
                     /gene="mnmE"
                     /locus_tag="TV193_000957"
     CDS             complement(17750..19126)
                     /gene="mnmE"
                     /locus_tag="TV193_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEL1513167.1"
                     /translation="MSITKEFDTIAAISTPLGEGAIGIVRLSGTKALDIAKSIFKGKD
                     LTTVASHTLNYGHIIKPSTGEVIDEVMVSVMLAPKTFTREDVIEINTHGGIAVTNDIL
                     QLLIKQGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMSIAIKQLDGSLS
                     QLISDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLRDKTREFQTLLEQLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNTLLREDKAIVTDIAGTTRDVIEEYVNIKGIPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTEQDKALLALSQDSNRI
                     ILLNKTDLEQVIEKDQLPEEAIPISVLQNQNIDLIEDRINQIFFDHTGLIEQDATYLS
                     NARHISLIEQAVQSLEAVNEGLALGMPVDLLQIDLTRAWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     gene            19398..19591
                     /locus_tag="TV193_000958"
                     /pseudo
     CDS             19398..19591
                     /locus_tag="TV193_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
BASE COUNT         5574 a         3626 c         4457 g         5934 t
ORIGIN      
        1 atttcacctc gtgacgatac cgttacttct ttttgaccaa gaaaagaaaa tgaaagtaaa
       61 aatatgacga ataatgttaa tggtataata agaattatcg caaaattatg atagcgtcgc
      121 tgataaaatt cagcacttct aaacagattt ggattcatga atatctcctt acttactaaa
      181 taaatgatga tagaagcctt gatgcgtcat taattcgtta tgcgaaccta tctcgattat
      241 ttttccttta tcaagtacaa caatttggct agtacgttca gcagtactaa gacgatgggc
      301 aacgaaaata atcgttttct cggtcattga cattaggtta tcaatcactt ttttctccgt
      361 taagacatct agtccgcttg tcgcctcatc gagaattaga ataggagact tggttaataa
      421 tgctctagct aatgcaattc tctgtttttg tccaccagaa aatcctgccc catcagatag
      481 ttctgtctga tagcccatag gcatttgttc aatatcttct ctaatttctg ccatatcaca
      541 ggcattgata atatcctctt gagtaatcgc ttggtttgca ccgagagtaa gattttctaa
      601 aattgatcca ctaaaaatat aagcttgttg aggcagatat tggttatcga aacgtcctaa
      661 atggtaatct gacaaatcta tcaaattatc tcaaacggtt gaatttaagt cttaagcggt
      721 aaatttttcc catttaggac gtttcgatga ctgtttagga aatggagaac aaattttaac
      781 cgaaagtgtt atactaagtc tgtcaagctt gcaaccggac aaaataaaaa cacatataaa
      841 ggaggtattc gtcatggata caaaatttac agcgttgact gaagagcaat tgaaatcagt
      901 tgagggtgga aaaaatggag ttgtaaaatt acctggaggg accggtgtat attgttggaa
      961 tacaggaaaa aatagtgcaa aatgtggtat ggactggagt gtggcaggac catatgttgg
     1021 taagataatt gtcaatggtt gggttaacca tggaccttgg gcaagtcgtc cataatttta
     1081 atttatatag agaggtgtga aatcatgaat gaaagagatt tagtacagct gatagaacag
     1141 actctaaaag atgaagaggt gcaaaataat gtcacttata ggaatctttt ggaagaaagt
     1201 ctccagcaat tatcactcaa aaagcctgtg tatttagtta gtaccaggtt agcaggacat
     1261 atttcaacct atctaatgac aaatcattat gaggcaccaa aagcgattat agttcttgct
     1321 caatctatcg catcaacccc agctaaacat agaggtttaa tttctatacc attctggtta
     1381 agtaatatat ttcgttaaaa aatattttca gatcaggatt tagaaggagt tgtagattgg
     1441 caatgcactc ataaaataag acacattttt tggagttttt tgcttgaact cctaactttt
     1501 acattagtct ataaacagtc aaaggaagtt ctttcaatct ctcaaattgc aaaacaattt
     1561 tggctatatt ttaaaagtac aattttgatt ccaattttag ttacaatcat tcttataaag
     1621 gagattttgt caagtacatt acaaataatg atttattttt accttaatgt tgttgtcatg
     1681 tgctacgcta ttggaatgat cttatcgtta ggttatgtga tttcacccaa gcactctata
     1741 ttcaataaaa ttaaaaatat aaaattaaat aatagagtat cccaagagat tgccgaatcc
     1801 caatttacca gtcttttaga gcgaagagcg acttgaagaa actgataaat ttatttggtt
     1861 ttctgctaaa aatcctgcca aaaaatcttt ggcaggattt ttattttact aagagatatt
     1921 taggagtggc tttgtcattt aatgcagatt atgatatagc aggagacata ttgttgaagc
     1981 tgtctatgtc acttttggtg gcaggtaggt cttattggaa ttggtgactt atgacattta
     2041 tcggtggctg taagcgtttg actttttcac gtttcatagt ggtccgctct ggaatgagtg
     2101 ggtatttttt cagaatatga tcaaagatag atgacatgtt ttacagcagg ctatagctgg
     2161 tatgatttgt ttaaaaaatc aaggccaatg ataagtgctg ggtgacataa gtcttatggc
     2221 tttacttctt gttagcttgt gtcagcaggt gctgagtcaa tcgttgtagg aattatcgta
     2281 aacctaacag tagctgctgt tctatttgtt tattttctgg tttctattca aatttctaaa
     2341 atgctagggt aacaaatatg aaacaagcaa gtggcgtact gcgaacagct tgataactta
     2401 ttgcctgctt aaagagggtg ctgttatgct tggttttatt aggcttatgg catgggatta
     2461 aaaggttgct gtagcgccat tgtcattatt ttggtacaat aataggtaaa agactaaatg
     2521 tataggaaaa tagaatgaac agtcaagaat taaaaaaacg tcaggagaac attcgtaatt
     2581 tctctattat tgcccacatt gatcatggta agtcgactct tgctgaccgg attttggaaa
     2641 agacagaaac ggtttcaagt cgtgaaatgc aggcacagct ccttgattca atggacttgg
     2701 agcgggagcg tgggattacc atcaagctaa atgcgattga gctgaattat aaggctaaga
     2761 atggtcaaga ttatattttt cacttgattg atacaccagg gcatgtggac tttacctatg
     2821 aggtgtcccg gtcactagct gcctgtgagg gtgctgtttt agtggtggat gctgctcagg
     2881 ggattgaggc acagacccta gcaaatgtct atctggcgct tgataatgat ttggaaattc
     2941 ttccagtgat caacaagatc gatttgccag cagctgatcc tgagcgggtt cgtcaggaaa
     3001 ttgaggacgt gattggtcta gatgcttcgg aggctgtact tgcctctgca aagtctggga
     3061 ttggtattga agatatttta gagcaaattg ttgaaaaggt tcccgcaccg tctggtgatg
     3121 ttgatcaacc gctgcaggcc ttgatttttg attcggttta tgatgcttat cgtggggtta
     3181 tcctgcaggt gcgtgttgtc aatggtatgg tcaagccagg tgatacgatc caaatgatgt
     3241 caaatggaaa aacctttgat gtgactgagg tggggatttt tacccctaag gctattggta
     3301 gggattttct tgctactggt gatgttggct atattgcggc ctcaatcaag acagttgctg
     3361 atacgcgtgt cggtgatacg gtcactctgg ctacaaatcc tgcagcagag cccttgcatg
     3421 gctacaagca gatgaatcca atggtgtttg cagggattta cccgattgag tctaacaaat
     3481 acaatgatct tcgtgaggcc ttagaaaagc ttcagcttaa tgacgctagc ttacagtttg
     3541 agcctgaaac ctcgcaagca ttgggctttg gttttcgttg tggctttctt gggctgttgc
     3601 acatggatgt cattcaagag cgtttggagc gtgaattcaa cattgatttg atcatgacag
     3661 ctccgtctgt tgtctatcat gttaatataa ctgatggtga catgcttgag gtctctaacc
     3721 cgtcagaatt tcctgatcca actaaggtag atagtattga ggagccttat gtcaaagccc
     3781 agatcatggt gccgcaggag tttgttggtg ctgttatgga gttggcccag cgtaagcgtg
     3841 gagattttgt gacgatggat tatattgatg acaatcgtgt caatgtgatt taccatattc
     3901 ccttagctga aattgtgttt gacttctttg ataagctgaa atcatcaacg cgaggctatg
     3961 ctagctttga ctatgaaatt gctgaatacc gtcgctcgca gctggtgaaa atggatattt
     4021 tgttgaatgg tgataaggtt gacgctctta gctttattgt tcatagagca tttgcctatg
     4081 agcgcggtaa gctgattgtt gagaaattaa agaaaattat tcctcgtcag caatttgagg
     4141 tgccgattca agcggctatt ggtcaaaaga ttgtggctcg ctctgatatc aaggccttac
     4201 gcaaaaacgt tcttgctaaa tgctatggtg gcgatgtttc ccgtaagcgt aagttgcttg
     4261 aaaagcaaaa ggctggtaag aagcgtatga aggctattgg ctctgttgag gtgccgcagg
     4321 aggccttctt gagcgtccta tcaatggacg atgagagtaa gaaatagtga catgttaagt
     4381 aaggagctgg atcatgcgat ctggctctta tgcttgatgt ctcgataggc tagaaaatag
     4441 ggcttgtgtc atgataggct tgtatgtttg agatggtttg gaacataatg actctatcat
     4501 atctgtagtg gattgacaaa gagccgtaaa ccattgatat ttggatagtt aatttcgagt
     4561 tattctgtag tactctctta aggtctttca tatgagcttt tctaatgttg gtttggttgc
     4621 ttttcatgat aagtcatatg ggattttttt ggtatactga aaaaagccta tagcctctac
     4681 agtggcgtct ccctctacag agatgataga gccagagtga ttgttacgat ctggagatgt
     4741 ggcgctaggc attaatgcag gaggacttaa ccagattgct gttaggcttg aaatcttaag
     4801 ctatattgat tgtcagcttg atttagagaa gtctaagttt atggctcaca aatgctcggt
     4861 ctttttgtta caatagagtt aatcagttat ttttataagg agacagctat ggaatctaag
     4921 gaagagcttc gccagcgtat tggagatttg gcttttgagg tgactcagca tgcagcgacc
     4981 gaaagagcct ttacaggtca gtatgatgat ttttttgaga aggggattta tgttgatgtg
     5041 gtgagcggag aggtgctctt ttcctctttg gataaattca attctggctg cggctggcct
     5101 gcattttcta agccgattca gcatcgtatg gtaaccaatc accatgattc atcacatggc
     5161 atgcggcgtg ttgaggttaa aagccgcgag gctggctccc atttggggca tgtttttaat
     5221 gatggcccta aggaggcagg aggcttacgc tattgcatta actccgccgc gctgaaattt
     5281 atcccctatg atcaaatgga gcaagagggc tacgccgaat ggttagggat ttttgataag
     5341 agctaggaat tgctagcggc caatgaaaag gtagagctct tagccaatgc tagtggctaa
     5401 atcaaagaaa taaaaaggtg gctaaagtac atagaaaaaa gaggtaagca gattggcagg
     5461 tggtcaatct gctttttgtg aggagacttt cagcctgctt tgcgctaaaa agtatgaaac
     5521 caataaacca cctactatgc gggtgtgtgt cggtggttag cttaagtttt ttcagttcgg
     5581 ttttacaagc ttctctaaaa ggactataat agctaatgga aaaggagatt catatgctaa
     5641 catctttaga aaaattaccg ggcgttttac tgtgcttgct gttagcactg cctgcctggt
     5701 atttgggaag cttatttcct attattggag cgccagtttt tgctatttta ttgggaatgc
     5761 tattggcgct tgtctatcag aagcgtgact acactaaatc tggaatcgca ttgacgtcca
     5821 aatatatttt gcagctggct gtggttttct tgggctttgg cttaaacgtg acacaggttt
     5881 tagtggttgg cttgcaatcc ctgccgatta ttgtagtaac gattgtgact gccttgggca
     5941 taagctattt gttcaaaaga tggttaaggc taccagccaa gacagctatc ttagttggtg
     6001 tgggctcgtc tatttgtggt ggctctgcta ttgcagccac agctcctgtc attgatgcgc
     6061 aggacgatga cattgccaag gccatttcgg ttattttttt gtttaatatc ttggcggcct
     6121 tgctatttcc agctttgggt cagatgcttg gcttatcaaa tcatggcttt gctatttttg
     6181 ctggaacagc agtcaatgat acctcatctg taacagctac agcgacagcc tgggacgcta
     6241 ttcaccagtc taatacgcta gatggggcaa ccattgtcaa attaaccaga acgctggcta
     6301 ttattcccat aacacttggc ttatctattt accaaaccaa gagcaggcag gcacatacga
     6361 cagagggttc ctttagcctc agaaaggctt ttccgacctt tattgtcttt ttcttgctag
     6421 cttccttgat aaccaccttt gctgctagct taggtctgcc aatggcaatc tttcatcagc
     6481 ttaagctact ctcaaaattc tttatcgtta tggccatggc agcgatcgga cttaatacca
     6541 atctagtgac cttagtcaaa actggtggta aggccatttt gctgggtggg atttgctggc
     6601 tagcgatcac atcagttagc ttagcaatgc aggcagcttt ggggagctgg taactgatga
     6661 gaatagctgg tgatacgctg ctttatagga aaagcaaagc ccttgctgct cctaaaaaag
     6721 cttgttagag cagctcactt agctgttaag tgtggcttgg tggggtgtaa gtaggctcta
     6781 tcagttagaa aagccatcag aacaaacgct atcattaagc tgaagccggg gaaactcggc
     6841 ttttacgtta tgcagaattg tctacatatt gaataggatt atccatttta aaaacgtttt
     6901 catttgatag aatacaatta tagcttggtt attagggtaa acgagattga acttcttatc
     6961 tggtttagct taagtaaaaa agcagttgga ggaagcatga aacgtaaatt tttaattggt
     7021 agtcatggga gaatggccag tggattgaaa agctctattg acattttggc tggtagaggt
     7081 caggaattac aagtcattga cgcttatatt gatgatagtg attatactga gcaggtattg
     7141 acctttatcg aagatgtagc agctgacgag caggcactga tttttacaga tttattaggt
     7201 ggcagtgtta atcaaaaaat agtaactgcc ctaatggaca gtggcaagga aaatatcttt
     7261 ttgatttcaa atagtaatct tgcagccttg ctatcgttga tgtttttaaa gccagaagaa
     7321 gagctgacaa aagacgagat tgtagcaacg attaacgatt ctcaggtgca gctggtggat
     7381 ctagctccag cgacagccgc agaagatgac ttttttaatt gaggaggaaa aatgaaatga
     7441 ttacacaaat tcgtgttgac gacagattga ttcatggaca ggttgctgtt gtttggacca
     7501 aggagcttaa tgcccctttg cttgtggtgg ctaacgatga ggctgctaaa aatgagatta
     7561 cacaaatgac tctaaaaatg gcagttccta atggcatgaa attattgatt cgctctgttg
     7621 aggactctat caaggttttc aatgatccac gcgcagtgga taagcgtatt tttgtcattg
     7681 tcagctcgat taaggatgct tgccagattg caaagcaggt gaaggactta gaggctgtta
     7741 acgttgcaaa tgtagggcgc tttgacaagt cagacccagc aactaaggtc aaattggctt
     7801 caagcctatt gttaaatccg gctgaattag aagcagcaaa agagctggtt agcctgccta
     7861 acctagatgt tttcaatcag gtactgccat ctaatagcaa ggttagcctg agccagctca
     7921 tcaaataaag aaaggtgtaa tgactatgtt agtaccagca acaatggcag ccttagctgt
     7981 attgatttgt ttcgggggaa attatttaac tggccaaagc atgatggaaa gaccgcttgt
     8041 ggttggtttg gtgacaggat tgctcttagg agatatgaag gtcggtatct tgatgggagc
     8101 gtcactagag gcacttttcc taggaaatgt taacattggt ggtgtcattg cagcagagcc
     8161 tgtaacagca acagctatgg caacgacctt taccatcatt tcacatattg atcaaaaagc
     8221 agctatgacg ctagctgttc cgattggcat gctagcagcc tttgtggtca tgtttttgaa
     8281 aaatgttttt atgaatatct ttgcgccaat ggttgataag gcagcagcgg caaaccatca
     8341 gggcaagctt gtcatgctgc actatggcac atggattgtc tattatttga ttattgcctc
     8401 tatttccttt atcggtatcc tagttggaag cggacctgtt aacgcctttg ttgagcatat
     8461 tccacaaaat ctgatgaatg ggctaagtgc agctggtggt cttcttccag cagtcggatt
     8521 tgccatgctg atgaagctct tatggacaaa taagctagca gttttcttcc tattaggctt
     8581 tgtgttgaca gcttatttga agctaccagc agtagctgtg gctgcacttg gtgcagttat
     8641 ctgtgtgatc agctcgcagc gtgatttaga gttagatgct attactaagg gagctatcag
     8701 taaccaaagc agctttgact ctaaagaatc agaagaggag gacttctttg catgagatct
     8761 caagacaatt taactaaaga agaaagaaaa atgctacgct ctgttttctg gcgttcatgg
     8821 accatgaatg ctagtcgtac aggagctacg caataccacg ctgttggggt tatctatacc
     8881 ttgttgcctg ttatcaatct cttttataag acagataagg ataaggcaga cgctcttgtt
     8941 cgtcacacca cttggtttaa tgcgaccatg catattaata actttatcat gggcttggtt
     9001 gcctcaatgg aaaagaaaaa cagtgaggat ccaacctttg acgctagtgc tattacagcg
     9061 gtcaaggctt ccttgatggg acctatttct ggtgttggag attccttttt ctggggtatt
     9121 ttgagggtca ttgcagctgg tattgggatt tcacttgcta gcacaggctc agcgatggga
     9181 gcagtagtct ttttacttct ctataatatt cctgctttta tcattcatta ttatagcctt
     9241 tatggtggct attctgttgg tgctggcttt attaaaaagc tttatgagtc tggtggtatt
     9301 aagattgtga ccaagacctc aagcatgctt gggtcaatga tggttggctc catgacagct
     9361 tcaaatgtga agtttaagac cattttaaca gttgctgcaa agggagccaa ggaagcagcc
     9421 tctatccaaa attatttgga tcagctcttt attggagttg tccctctttt agtaaccatg
     9481 accgcctttt ggcttttgcg taagaaggtg aacattaact ggattatgtt tggcattatg
     9541 ctattgggta ttgttcttgg tcttttaggt atttgctaat aatctcctag catcaaggat
     9601 aggtaaggca gggacttctt gctttgctta tccttttttg tagtgagggc tgctgaaata
     9661 gccacctgct tgcttaaatg gcttatggat ttgttagata gattaagatt ttcttagctt
     9721 tgagaaatga tttggtataa tagaaggaaa taagggaaaa ggctgcctat ggaagaaaga
     9781 tttaaaaagc gattgcagga tgatatttca catcattttt cacaccaatc attgattttg
     9841 tccattttac tgattggact ctttctcatt ttttcattgg cacctcagca aattgggctg
     9901 tatcaagatt tgaaggctgt tgaacatagc tatcaccagc tgattcggca aaataaggcg
     9961 cttttaacgg agctcaatca gcatattctg accaaatttg tgaatcatca gctgagctct
    10021 tctgacctta gcaaacaata ttatcaccta agaaaccgct cacaaagcca atcagagctg
    10081 ctggtttttg atgctaacag tcacatgctg tttgctagta atcagcatct gggaaatttt
    10141 tttcgcaatg ctgtctatat gacagaagtc ttaaaaaaag caaggcaaag gagtagcttc
    10201 ttgaggatca gtatggataa tgaggagggg cattatttac tgctgataaa gcctattaag
    10261 atagatcatc aggttaaggg ctattcgctt cttgtgatga atggtaagga ttttcttcag
    10321 ctatcacatc agattgcttc agattttgtg attgcagatc agtttgacaa tagctttgcc
    10381 tttaccaatc ggacctttat gacctcaagt ctgaataagc ttgacagtca ttttcttaag
    10441 ggctatttta tctttcacga gcatcgtgcc tttatcctaa gaaaggtcgc tcttagtcct
    10501 tctatcactc tttacagcta ccgccctttg attccagttt ctattgcact cttgttttca
    10561 ttgatgtcct ctgtcatgat ttatgctatt ttgtattgga agtctaaggc tctggcgacg
    10621 cagattgctt ctagcaattc agcagcgatc aatcagatga ttcttgatat gcaggccatc
    10681 tcaaggcagg aaaaaaatgc cattgacctg caaagtcaag atgaatttca atacctgtcg
    10741 gttcagatca atcagatgat tagccgattg caggcacttc atcagaagac cctagcctta
    10801 gaaaagcaaa atgtgagttt tgaaaaacgc atgctggaag cccaatttaa ccctcatttt
    10861 ctctataata cacttgaaac aattttgatt acaagtcatt atgacagtga cctcacagaa
    10921 aaaattgtcc ttcagctaac caggctgctt cgctatagct tagacgaatc acaggaggct
    10981 gtgtgtctgg gagaggattt ggctgtctta gaatcctatc tgttgattag ccagattagg
    11041 tttgaagagc tgcgctacac gatagctgtt gaaccagccc tagagaccct aagggttccc
    11101 aaattatttt tattgccatt gattgaaaat gcgatcaaat atggtctgcg ctatcgccat
    11161 gaccttgtga ttgagatcag cgtgagacag cttgctgatg gaatttactt tactgtagca
    11221 gataacggtc ctggaattag tcaaaaaagg caggccgata ttaaagagct cttgcattca
    11281 gaggattcac atcatggctt ggtcaattct tatcgtcgac tcaagcatca atttataaaa
    11341 gttgaattga tcttttgtca aagagatgag cgctttttac taacctatat ggttaaggag
    11401 taacagatgt ataagctact aattgttgaa gatgagcata ttattcgcaa atggcttcgt
    11461 tatgcgattg attatcatgc gctcaatatc cttgttatcg gagaagctaa ggacggtcag
    11521 cagggggcta agctgattgc agaggctaag ccagatattg ttttgacaga cattaacatg
    11581 ccgattatga ctgcctttga gatgtttgag gccacaaaag agcagtccta tgctaaaatc
    11641 attttgtctg gctatgctga tttcgctaat gcaaagtctg ctatccatta tggtgtgctt
    11701 gagtttttga ccaagccctt ggaaaggcag gccttacatg attgcttgct aactattatc
    11761 caaaagctgc aacagcagtc tcaagagcag gagctaagcc agcagcagga ttacctcaaa
    11821 ctgccacagc ctaatgacca attgcctgat gttgtccaag aaatgctcag ctggatccat
    11881 gagcattacc aggataaaat catgattggt cagttggctc acgatctggg ctatagcgaa
    11941 agtcacctct atcatttagc taaaaaatac ctgaaaatga cttttagtga ctatatcaac
    12001 caataccgcc tgaatcgagc aattcaattg ctgattgctg agccggatgt gatggtttat
    12061 cagcttgcag aggctgttgg catttatgac taccgctatt ttgatcgtgt gttcaaaaaa
    12121 tatttaggac aaacggtcaa ggatttcaga gaaacggtat tacaccagag atcagatagg
    12181 agttcattgt gacaagaaaa aagctgctat tagcaatggc aatagtgata ctaggtgtga
    12241 ttggctctgg cttgtatgct atctggaggc atcaagcagg accagctccc agcaaaccaa
    12301 gagaattggt tgttttgaca cccaacagtc aaaatatcct aacaggtacg atcccagcct
    12361 ttgaagaaaa atacggcatt aaaatccgtc tgattcaagg aggcacaggc cagctcattg
    12421 atcgcttgca aaaggacaag gaccagctcc atgcagacat cttttttggg gggaattaca
    12481 cacaatttga gagtcataag gagctatttg agccttacct ttcaaagcat attggctttg
    12541 tattgcctga ttacctgctg caaagcgagg tcgcaacccc ctatacgctt aatggaagtg
    12601 ttctcattgt gaataatgaa ttggcaaagg acatggttat taccagctat gaggatttgc
    12661 taaagccaga gctaaaggga aagattgctt ttgcagaccc caacacctcc tctagtgcct
    12721 tttctcagct gaccaatatt ctcttagcca aggggggcta cactaacccc aaggcttgga
    12781 gctatatcaa gcagttgatt catagcatga attcaatcaa atctgctagc tcatcagatg
    12841 tttatcagtc agtagcagaa ggaaagatga ccgtcggtct tacctatgag gacccctgtg
    12901 ttaacctttt aaagagtggt gccaacgttt ctattgtgta tccaaaggag ggaacggttt
    12961 ttttaccctc agcagttgcc attgttaagc aatctaaggc caaggctgat gccaaattgt
    13021 ttattaatta tatgttgtct ttagatgtgc agcgggcctt tggtcaatca accagtaata
    13081 ggccaattcg aaaggacgct aaggccagtc aagacatgaa gcctttagat gacattatca
    13141 cgctaaagga agactatgat tatatcacaa gacataaaaa ggatatttta gaacgataca
    13201 atcaattgag aaagaccact gactaaatgg ctttgttata tgaaacagtt catgctgtgc
    13261 tgcacctgaa tcgttagctg ctttgtctag ctttttgagg tcaatctctg cttgggctgt
    13321 tttttatgtt accataaccc actgcatttg tttagaaagt caagcgagat cttaatagcc
    13381 agttataata ggtctttgag agggagtctg agcttgcttg aggtggcaag aagatctgtt
    13441 ttgacgtcaa atggctgaat ttttggtaaa atgatagcat gaatgaactg ataaaacaca
    13501 agctagagct tttgccagat agtcctggct gttatttgca taaggataag gctggcacta
    13561 ttatttatgt tggcaaggcc aaaaatctga gaaatcgcgt acgctcttat tttcgaggaa
    13621 gccatgatac caagacagag ctgttagttt ctgaaatagc tgattttgag tttattgtca
    13681 caggatcaaa tacagaagca ctcttattgg aaatcaattt gattcaagag aacatgccca
    13741 agtacaatat caagctaaag gacgacaagt cttatccctt tatcaagatc actaacgagc
    13801 catttccaag actattaatc acacgtcaga ttaaaaaaaa tgacggcctg tattttggtc
    13861 cctacccaga tgcttacact gccactgagg ttaaaaagct gctagaccgt atttttccct
    13921 ttaaaaaatg caaaaaccct gttaacaagg tctgctttta ctatcattta gggcaatgtc
    13981 aggctcacac gatttgccat acagacaagg cttattggga cagcttggtt gctgatgtca
    14041 agcagttttt aaacggtaag gacgacaaga tcattgatga tttgcgctcc aagatgcttg
    14101 aagcttcgca caatcaagaa tttgaacggg cagctgaata tcgtgatttg atttcaggta
    14161 ttgccaccat gcgaaccaag caaagggtga tgagtaagga cttgcaggat agggatattt
    14221 ttggctattt tgttgataag ggctggatgt gtgtgcaggt cttttttgtc cgtcagggta
    14281 agctcattca gcgagatgtg aatatgtttc cttattacaa cgaagctgaa gaggattttt
    14341 tgacctatgt cgggcaattt tatagcgacc aacggcattt gatccctaag gaggtcttta
    14401 ttccagagac gattgatgag accttggttg cagccattgt tccagcaagg attgtcaagc
    14461 cgcagcgagg ggaaaaaaag cagctggtcg ccttagcaac taagaatgct cgggttagcc
    14521 ttcagcaaaa atttgatttg ctggaaaagg atttaagaaa aacaagtggt gctattgagc
    14581 atcttggtca gctgttaggc attgaaaagc ctgttcgtat tgaggccttt gacaattcaa
    14641 acattcaggg cacaagtccg gtagctgcga tggtggtttt tgtcgatggg aagcccagca
    14701 agaaggacta tcgcaaattt aaaatcaaaa cagtgattgg tccagatgat tatgcgagca
    14761 tgagagaggt gatttatcgt cgttatagcc gcgtgaagca tgaagggcta caggcacctg
    14821 atttgattat tgttgatggt gggcagggtc aggtcaaggc tgctcgtgat gtgattgagc
    14881 accagctagg ccttagcatt ccagtagctg gtctgcaaaa aaatgacaag caccagaccc
    14941 atgaattgct ttttggtaac cccttggcag tggttgagct gccgagaaat tcagaagagt
    15001 tttttctgct gcatcgtata caagatgagg ttcatcgctt tgccattacc tttcacaggc
    15061 aggtcaggag taaaaatgcc ttttcatcaa agctagatca cattgcaggc ttagggccaa
    15121 aacgcaaaca gctactactc aagcgattta aaagcatgac tgctcttgaa caggctagtc
    15181 ttgaagaaat tcagcagcta gggattccaa aaacagtcgc tgaggcactg tttgatcacc
    15241 ttacctcaaa aagtgaggtc tgaattggcc ttgtcaggag ctcaagcagt ctgaattttc
    15301 ttgacaaaag tgaaaaaata gctgaaacca gtttcaaaaa atgatagaat gatactacaa
    15361 cataaaagaa ttagatagga agcatttgca gtgaaatttc tcgaattaaa caaaaaacgc
    15421 catgctatta aacggtttaa cgataagccc gttgattata atgacttgcg aacagctatt
    15481 gaggttgcca ctctggcacc aagtgctaac aatattcagc cttggaaatt tgtcattgtt
    15541 gaggaaaaaa aggcagagct ggcaaaggat ctgccgttgg ctaataagac tcaggtagag
    15601 caggctcagt atgttattgc cctgttttct gataccgacc tcattcagcg ctctcgtaag
    15661 attgcccgca ttggggtcaa gtccttgcct gataacttga ttggttatta catggagacc
    15721 ctgccgccac gttttgctac ctttactgag acccaaaaag gcgaatatct ggccattaat
    15781 gctggcttgg tggcgatgaa tttggtcctt gccttaacgg atcagaaaat ggcctcaaat
    15841 attattttag gctttaataa aaagctaact aatgagattt tagatattga tccacgcttt
    15901 cgtcctgaat tattgataac tgtggggtat agcgatgaca agccagagcc tagctatcgc
    15961 ctaccagtag acgaaatcat tgaaagacgc taagatacac aactactcgt ccagctagcc
    16021 tataagtttt tggatttagg aggatagcga ggcaacacat aaaggagaaa aagatgacaa
    16081 caattgattt taaagcagag gttgataagc gcaaggaagc tatgctagag gatctatcaa
    16141 acctattaag cattaattcc gagcgagacg atgctaaggc agatgccaag cacccatttg
    16201 gtcctggtcc ggttaaggcc ttggagttct ttcttgccat ggcagagcgt gatggttacc
    16261 aaacgcgtaa tattgataac tatgctggtg attttgaatt tggtcaggga gatgaggttt
    16321 tagggatttt tgcccattta gacgtggtac ctgctggtag tggctgggag acagaccctt
    16381 ataagccggt gattaaggat aatcgtatct atgcgcgtgg ttcatctgat gataaggggc
    16441 caaccatggc ttgctattat gccctgaaaa tcatcaagga attaggcttg ccagtttcta
    16501 aaagggttcg cttcattgtt gggactgatg aggagtcagg ctggggtgat atggactatt
    16561 attttgctca caatggcttg aagaaccctg attttggttt ttcaccagat gctgaatttc
    16621 ccattatcaa tggtgagaaa ggaaacatta cagaatacct tcattttgtt ggtcaaaatg
    16681 ctggagcttt tgtccttcat cgcttccaag gcggtttacg tgaaaatatg gttcctgaat
    16741 cagcgacagc tctgatcagc tcaccgcatg agcttaatgt tatcgaagct tctttggagc
    16801 aattcttatc tgagcacgca gtgacaggat ctgtcaaaga ggctgatggg ctattggaag
    16861 tgaccattat tgggaaatct gctcatggct ctacaccaga ggctggtgtt aacggtgcaa
    16921 ccctgctggc taaattctta aatcaattta gctttgatgg cgcagccaag gcttatttgc
    16981 atattgcagg tgaggtgctt catgaggatt tcacagcaga aaagcttggc ttggcttata
    17041 cagatgacaa aatgggtgcc cttagcatga atgcaggtgt ctttagcttt gctaaggatt
    17101 cagatgacaa taccattgcc ttgaatttcc gttatccaaa gggaaccaat gcagcagtgc
    17161 taaaggcagg gcttgagcaa ttaccaggct tgactaaggt taccttatct gagcatgaac
    17221 acacccctca ctatgtgcca atggacgatg agctggtctc aaccctccta tccgtctatg
    17281 aaaagcaaac aggactcaag ggctacgagc aggttatcgg tggtggcacc tttggacgct
    17341 tgcttgagcg tggtgttgcc tttggtgcga tgttcccagg tgatgaaaac acaatgcatc
    17401 aggccaatga atacatgcca ttagacaata tttaccgatc agctgccatt tacgccgaag
    17461 ctatttatga attgatcaaa taagagattg aacaagctct ctgtctaaga tgagccttgc
    17521 taatattaac gaataaaagc cttatgaagt tagtcgttta atgagacttc ataaggcttt
    17581 ttgtttggcg tcaagccatt atttacaaag agaaatgcca cagtggatca tcttttgaaa
    17641 agtccttgta aaaacagacg taaaactagt tttagaggag acattgatag gcagtcatgc
    17701 ttatcaagag atcttgtcta gcagttatgg caaaaagatc agtgaactat tattttccaa
    17761 ggcagaactg actgaacaat tgagtaatta attcatcagg tgcggcatcg cctgtgattt
    17821 ctcctaggat ttcccaagct ctggtcaaat caatctgtaa gagatcaacc ggcattccta
    17881 aagcaagtcc ttcattgaca gcctctaagc tttgtactgc ctgctcaatc aaggaaatat
    17941 gacgagcatt ggataggtaa gtcgcatctt gctctattag cccagtatga tcaaagaaaa
    18001 tctgattgat ccggtcttcg atcaggtcaa tgttttggtt ttgcaaaact gatattggga
    18061 tcgcctcttc tggaagctgg tctttttcaa tgacctgctc cagatcggtt ttattgagga
    18121 gaataatgcg attgctatcc tgactaaggg ctagcagagc cttgtcctgt tcggtcagct
    18181 tttccgaagc attgagaact aaaaggacca gatcagcctc ctgtagggct tttttagacc
    18241 gctcaacacc aatttgctct actaaatcat ctgtttctct aattccagca gtatcaacta
    18301 gctttagagg aattcccttg atattgacat attcttcaat gacatcacga gttgttcctg
    18361 caatatcagt gacaatggcc ttatcctcac gtaacaaggt attgagcaga ctagactttc
    18421 ctacattcgg tcggccgata atagctgttg acaagccctc acgtaggatc ttcccgcgct
    18481 tggcagtacg taggagctgc tctaaaagtg tttgaaattc tcgcgttttg tcacgcaaaa
    18541 gagcagtggt catttcttcg acatcatcat attcggggta gtcgatatta acctcaacct
    18601 gggctaaggt atttaggatt tcttgacgtg tgtcgctgat gagctgtgat agggagccgt
    18661 ctagctgctt gatagcaata gacatggcct tatcagtctt tgcacgaatc agatccatga
    18721 ctgcctcagc ctgtgttaaa tcaatacggc catttaaaaa agcacgcttt gtaaattcgc
    18781 cgggctctgc cattcgagct ccctgtttaa tgaggagctg taaaatgtca tttgtcaccg
    18841 caataccgcc atgggtattg atttcaatca cgtcctctct ggtaaaggtt tttggcgcca
    18901 acatgactga taccatgacc tcatcaatca cttcacctgt gcttggcttg ataatatgac
    18961 catagttaag ggtatgtgag gcgactgttg ttagatcttt tcctttaaag atcgatttag
    19021 caatgtccag agccttggta ccagacaagc gaacaatgcc aatagctcct tcacctaacg
    19081 gagttgaaat ggctgcaatt gtatcaaatt ctttagttat actcatgcct tctattgtag
    19141 aacaagtcag catagaaagc aaggtattgc attagctgct cgttgtcgtc attcttgtct
    19201 agtggcaaag cctcaaaagc agttgtaaac agctaaagct atgattaaaa agccttgtat
    19261 ggtaagtaca ggataaagcc aaaaagctga tgagttttag ataaacatac aggctcgaaa
    19321 agccctatta aaccgacagc aacaatcctc acacagtata gttgacttaa ctacctgatg
    19381 tcatttctgg ctgtttttat aatgacaatg gcaatatcgg ttattttgac tatgctgggt
    19441 gcttgtatcc tagtggactg actgacaatc agggcttctt tttcaaccac gaaaacatta
    19501 aaaaagtctg gtttggaggc tatattgacg atagtgaaag agaagctcaa gactttttta
    19561 aaaaagaggc aggctatatt aaatatccta a
//
LOCUS       DARYXS010000033        18954 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.033, whole genome shotgun sequence.
ACCESSION   DARYXS010000033 DARYXS010000000
VERSION     DARYXS010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18954
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.033"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..376
                     /locus_tag="TV193_000959"
     CDS             <1..376
                     /locus_tag="TV193_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HEL1513168.1"
                     /translation="QGGEKKDISYIEQEGDLSALFQSETDLSIKKKQQHRKETSQTTK
                     NHLFMTHIDSDNLVARYQPLLFNPEQRLAATDDQYGVLLAQKTIGITWQMLAILLVGA
                     VLTGYSLTRGRLSRQKHKRHHE"
     gene            692..933
                     /locus_tag="TV193_000960"
                     /pseudo
     CDS             692..933
                     /locus_tag="TV193_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein"
     gene            936..2093
                     /gene="essB"
                     /locus_tag="TV193_000961"
     CDS             936..2093
                     /gene="essB"
                     /locus_tag="TV193_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HEL1513169.1"
                     /translation="MEKKMKTIIRELLVEDVKGDAEVAYTLLASEHSLFVPSKLEQAF
                     DKLILEASIDDMYDWSALEAMIVEEKLRHLLNLSELFDQLLDSKFTYSFTPDNLVFNR
                     NAEPQLIFRGIKDQVPPYQPLEREVFVNTLKCMTIALLDKKTSYDALMGGKLPFYKGN
                     LFCEAVAKAEALQELQELLATKYHEEQKDNKEHFSRVANKTISRLKLTTICSSVLALL
                     SLAGVLYFLLFAMPYQEMVASLRMAFINQDYSKVITTAKHTDSKALSQGDKYIVAYSV
                     IMTEPLTDKQKEELSKISNQSNEDYLRYWVLIGQARIDDAMDIASYLDDPQLLMYGLT
                     KKIDDVQRDPNLTAEARTEQLNSYKSKLDELKKAYLTPKEEKAAGSSSDKE"
     gene            2105..6481
                     /gene="essC"
                     /locus_tag="TV193_000962"
     CDS             2105..6481
                     /gene="essC"
                     /locus_tag="TV193_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HEL1513170.1"
                     /translation="MTYLIYDDNAYHLYSDTVYQLGPSSGSDIFLPLLEDITLSVEGS
                     GVVLLEESYSTGKHCVALSDEVTVTLLILEAVTKYLLPDSSLYISGETTAALQLLDYP
                     SELVLTLDSDSASCYSPVSYYLNGKWTKGKQPLKASDELVFSDGLVLSFQDQLLSIQS
                     LYAIQTALLPLTEAVAEDRASEFHRSPRIILREPEGKVTIASVPTDDEGKRQSLLKLI
                     ITPLAMIVFTGLSYVFFRGGGMLMMMMGMSVITIGSSIHSYFSDKKWHKEAQQQKIKD
                     YLAYLDTKYVELAGYREEQIEALLYHYPNMTTILEMAQKTDRRIYEKAPYHFDFLTYR
                     LGLGDTPASFHIDYSDSELTKHHEKAKQRVQELIAYYQVTAQVPIQNAIASPIGYIGA
                     RKVVIEQVQQLMMQIATFHSYHDVQFIPIFREEELPLWNWSRWLPHTKLKVLNSRGFV
                     YSQRTRDQLLTSLYQLIKERQLDSEQDKGTEKQYTPHYIVLITDMSLMLDHNIMEYIN
                     EDLSHLGIHYIFVEEVIESLPEHVKTVIDYRGDKHAQLILQEGLYLNKAFTPLQPLSM
                     KDKEVFARHMAGINHVETLRNAIPNSVTFLEMYGVNKVEELNLLKRWKENEAYQTMAV
                     PLGVRGRDDILYLNLHEKAHGPHGLIAGTTGSGKSELVQSYILSLAVNYHPYEVAFLL
                     IDYKGGGMANLFADLPHVVGTITNLDGNQANRALVSIKAELKKRQRIFLENDVNHIDQ
                     YTKLFKEGRVKEPLPHLLIISDEFAELKANQPEFMDELVSTARIGRSLGVKLILATQK
                     PSGVVNDQIWSNAKFKIALKVQDVADSREVIKTPDAAEITQVGRAYLQVGNNEIYELF
                     QSAWSGADYNPKGRHTIQHETTVYEITANGQYQAINKDLSGLDKKREAKSMPTELDAV
                     VAEAQQLFEDLHIPKVASPWLPPLSEKIYASDLQSTHFKDYWGQTQDLQPVLIGYQDI
                     PERQEQSPLYFHMEKAGHILLVSSPGFGKSTFLQGFALDVMRKQTPAQAHFYLYDFGT
                     SGLIALSDFPHVADYFTLDETDKIMKSLRYLSEEIKTRKHALSKAKATNLNQYNQLSK
                     DTFPALFVIIDGFDSVMDAPFVDAVYNVLNVIARDGASLGMYLVVTLSRLNTMRLQLQ
                     SNFKTKLSLFLFDNSDLSSVVGRSNIPLDDIKGRAIMKRDDIIQFQIALPYSSEYYTD
                     YMAEVKREVEAMRAVYQGALPAAIPMLPEKVTPDMIAAMSDSAQDFVIGLEREDVVPA
                     GFTFKKSILMASDSPAFVANYYKLLDFQLQRLADQYRTVILDPSQRIARQFFEDSQRF
                     STALDVGDTLRAIVEDFKKRLAAPGQDYQKWLVVIPDIAATALAAGISEEDFKQLVTE
                     GSQYGVTLIFVGAYQDLVNNTYDNFVKLANQLIEQVFLGMRISDQSHTRYAYISNEPS
                     LRPTQGYILYPEGYDFIQLLEI"
     gene            6494..6823
                     /locus_tag="TV193_000963"
     CDS             6494..6823
                     /locus_tag="TV193_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1513171.1"
                     /translation="MSTVTILPLGSIVILKGNTKKMMIIARVIAAPIKGEVYRFDYGA
                     CLYPEGMMGDSLIYFNHDDIFKIIQEGYADDDNALMLETIAQALATTDIPKGDVSALN
                     DRKTVED"
     gene            6827..7261
                     /locus_tag="TV193_000964"
     CDS             6827..7261
                     /locus_tag="TV193_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HEL1513172.1"
                     /translation="MGQVDYNHINQLQRQVDQHRASLSTATAEIASIDEKLERLRCAK
                     ASVGAIQGDVHQIKVSVMAKRDQPDWKGERKDRLMSSWEEFSHDYRHFQLELDAYYDA
                     ICDTITRLENQKYEQQGLIGWCQSMINSLGNEIEKLFHIREG"
     gene            7263..7547
                     /locus_tag="TV193_000965"
     CDS             7263..7547
                     /locus_tag="TV193_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1513173.1"
                     /translation="MFGVIQLSEVVFGAHVLSLTAAKASLSDVKASFPSHQSSSKVLD
                     LYQSEFEALSQLVAAYARLLEKDIALIAEAGQELALTDKQLGQAIGFRLQ"
     gene            complement(7618..8920)
                     /locus_tag="TV193_000966"
                     /pseudo
     CDS             complement(7618..8920)
                     /locus_tag="TV193_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9301..10011
                     /gene="ccdA2"
                     /locus_tag="TV193_000967"
     CDS             9301..10011
                     /gene="ccdA2"
                     /locus_tag="TV193_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEL1513174.1"
                     /translation="MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSI
                     TIFGKKLYWYGIVKTLAFISGLSTIFIILGYGAGLLGNILYAAWFRYLLGAFVILLGI
                     HQMEIVTIKKLQFQKSVAFQNKKDRNAVLNAFLLGITFSFGWTPCVGPVLSSVLALAA
                     SGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVI
                     MGLLLMTGNLNSLSGLFE"
     gene            10025..10675
                     /locus_tag="TV193_000968"
     CDS             10025..10675
                     /locus_tag="TV193_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEL1513175.1"
                     /translation="MKKTTFLTTGLACLALLTACSAKDKMAMNDSKKDHMTRTDDKSK
                     MKKDQKDKMSDKKDMMSDDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKK
                     VYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTD
                     FKDLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGVLAKKHIGYAKKSEIEKTLKEIK"
     gene            10693..11805
                     /gene="msrB"
                     /locus_tag="TV193_000969"
     CDS             10693..11805
                     /gene="msrB"
                     /locus_tag="TV193_000969"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1513176.1"
                     /translation="MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKG
                     TSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQL
                     LHQTGHAETVQVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGIYYTDPS
                     DLTTIDMVFQEKASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASY
                     PVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEP
                     LFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGP
                     KDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD"
     gene            12073..12813
                     /locus_tag="TV193_000970"
     CDS             12073..12813
                     /locus_tag="TV193_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1513177.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELF
                     QENPYDIVLTDINMPKLNGIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLT
                     LKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVG
                     FEDINYFSQRFKQLVGMTPRQYKKGEGQ"
     gene            12810..14528
                     /locus_tag="TV193_000971"
     CDS             12810..14528
                     /locus_tag="TV193_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1513178.1"
                     /translation="MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERE
                     TRQSIRQSSQFIDAYIKPLKETTSALASHAEIQSFAKAANSSHQEQVLALMTTVLSTN
                     SDLRSAVLVTKDGRMVTTNPKLIMTTSHDMMAEPWYKSAIDRKAMPVLTPARQLSSHS
                     KKDWVVSVTQEVVDETGNNLGVLRLDIGYNTIKSSLDQLQLGRRGFAFIVNDKHEFVY
                     HSKNTVYSSEREMAAMKPYLAVADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHV
                     QRQIFWSFLGTGLLATVICGLGTVFVLRSWIGPIRRLQALILAIQKGNRQLRAEEIGS
                     PELADLARQFNAMLDQIDSLMISVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSQRVVDVTKSLAKYFRLALNQGNELISLADELDHARQYLFIQKQRYGDKLHYE
                     IKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGMIRVTVLEADRHVILSVWDNGK
                     GISLADDSSQALLECGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLYLPKPLD
                     GLNELP"
     gene            14567..15655
                     /locus_tag="TV193_000972"
     CDS             14567..15655
                     /locus_tag="TV193_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEL1513179.1"
                     /translation="MSLESDYFKRKSPVFEALIPYGFTQEGDTYCYQESFMEGDFKAL
                     ITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTP
                     FQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKV
                     LQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTK
                     SRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYI
                     TAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNA
                     VRGPRRLSPQLVAFLKEKEYFKDVKQKE"
     gene            15670..16374
                     /locus_tag="TV193_000973"
     CDS             15670..16374
                     /locus_tag="TV193_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEL1513180.1"
                     /translation="MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADS
                     HDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPL
                     VDIYNTASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKD
                     DAGAVCRCLNWRDGERTMITDRTKNAFLVIEALDSKTQARLQDALKFIEDKAKCYLKA
                     ETALYTLDQASPSITF"
     gene            16634..17122
                     /locus_tag="TV193_000974"
     CDS             16634..17122
                     /locus_tag="TV193_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEL1513181.1"
                     /translation="MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRT
                     KTMFLTTRKKNHFYLIIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVS
                     PFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIV
                     DL"
     gene            complement(17632..18105)
                     /locus_tag="TV193_000975"
     CDS             complement(17632..18105)
                     /locus_tag="TV193_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1513182.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSR
                     DMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGL
                     AQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK"
     gene            18246..18926
                     /locus_tag="TV193_000976"
     CDS             18246..18926
                     /locus_tag="TV193_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1513183.1"
                     /translation="MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFF
                     EGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKEGLIAVKGKYLTYLDK
                     NYFLQYTT"
BASE COUNT         5447 a         3579 c         4393 g         5535 t
ORIGIN      
        1 tcaggggggt gagaaaaaag acattagcta catcgagcaa gagggcgatc tgtctgccct
       61 atttcaatca gagacagact taagcattaa aaagaaacag cagcatcgaa aagaaactag
      121 tcagacgacc aagaatcacc tatttatgac tcatattgat agtgacaacc ttgttgcaag
      181 gtatcagcca ctcttattta acccagagca gcgtctggca gcaacagatg accagtatgg
      241 tgttttgctc gctcaaaaaa ctatcggcat cacttggcaa atgctggcca tacttcttgt
      301 gggagctgta ctgactggct attctctgac tagagggcga ttatcaaggc aaaaacacaa
      361 aagacatcac gagtagaatc gtctgtcaag agtatctact cactgaaaat agagggctag
      421 cttaggagac ttcctaatgc tgcatttata agaaaaggct ctcagctgtt ttgacagtat
      481 tgggcaaggc cttagggcct gtagcaaata tgaagagcag ctttgatcag caggtagcaa
      541 gtcagtcaat acaaatgctt gaaagcctac ctgctaagaa aagtgtgtgt tctacgatac
      601 tttagtgatg tgaatcacct caagaggctt tagctagctt ggcaggtgat gtcaggtgac
      661 atggaaactt atcaggaaag ggctaatttt tatggagaat tatattagta tcagtcttga
      721 ttgctcgcat ttttttcaca ggaatttgat ttgcgggtac caaggacaat gacctttaag
      781 gagctattac aaatcgtatc agatgcttat ggtttgggat ttcaggtggt aaatcccagt
      841 gctagaaatg agcaaggtgg tcagctgatg acaagcacca gtcgcatgga taccctaaaa
      901 aatggtgcac tgttagtatt ggaaaattta taaacatgga gaaaaagatg aaaacaataa
      961 tacgtgagct attggttgag gatgttaaag gagatgctga ggttgcttat accttactag
     1021 cttctgagca ttctcttttt gttccttcca agttagaaca ggctttcgac aagctgattc
     1081 tagaggctag cattgatgac atgtatgact ggtcagccct agaggcgatg attgttgagg
     1141 aaaagctaag gcatttgcta aatcttagtg agctgtttga tcagctcttg gactcaaagt
     1201 tcacctacag ctttacacca gataatctgg tctttaaccg taatgcagag ccacagttga
     1261 tttttcgggg aatcaaggat caggttcctc cttaccagcc gcttgagcgt gaggtctttg
     1321 tgaatacact gaaatgtatg acaattgcct tgcttgataa aaagaccagc tatgacgctc
     1381 tgatgggtgg caagcttccc ttttacaaag gcaatctttt ttgcgaagca gtggccaagg
     1441 ctgaggcgct gcaggagttg caggagcttt tagcgacaaa gtaccatgag gagcaaaaag
     1501 acaataaaga gcatttttct cgtgttgcta acaagacgat atcgcgcttg aaattgacca
     1561 ccatttgttc atcagtgctt gctttgttgt ctttggcggg cgttctttat tttctattgt
     1621 ttgctatgcc ttatcaggaa atggttgcta gtctgcgtat ggcttttatt aatcaagact
     1681 attctaaggt tatcacaaca gcgaagcata cagacagtaa ggccttaagc cagggtgata
     1741 aatatattgt ggcttactct gtcataatga cagagcctct aacagacaag caaaaggagg
     1801 aattaagtaa aatatcgaac cagtctaatg aagattattt acgctattgg gtgctgattg
     1861 gtcaagcaag gatagatgat gccatggata ttgcgagcta tctagacgac ccgcagctct
     1921 tgatgtatgg cttgactaag aagattgatg atgttcagcg agatcctaat ctgacagcag
     1981 aggcgcgtac agagcagctt aacagctata agagcaaatt agacgagctc aaaaaggcct
     2041 acctgacgcc taaagaggaa aaagcagcag gctctagcag tgacaaggag tgacggagga
     2101 atttatgaca taccttattt atgacgacaa tgcctatcac ctttattcgg ataccgttta
     2161 tcagttgggg ccttcatcag ggtctgatat tttcctgccc ttgctggagg atattacctt
     2221 atcagtggag ggatcaggtg ttgtcctact ggaagagagc tacagcactg gtaagcattg
     2281 tgttgctctt tctgatgagg ttacagtgac cttacttatt cttgaagctg tcactaaata
     2341 cctgctgcca gactcctcgc tttacatttc aggagagact accgcagcac ttcaattgct
     2401 tgattaccct agtgagctgg tgctgaccct agactctgat tctgccagct gctatagccc
     2461 ggtgtcttat tatctaaatg gtaaatggac gaaaggcaag cagcctctta aagcatctga
     2521 tgaacttgtt ttttcagatg gcttagtgct tagttttcag gatcagctgc tatcgattca
     2581 gtccttgtat gctattcaga cagcattgct gcctcttaca gaggcagtag ctgaggatag
     2641 agccagtgaa tttcatcgtt ctcctaggat tatcctgcgt gagcctgagg gaaaggtgac
     2701 gattgcttct gtacccacag atgatgaagg gaaaagacag tctttattaa agctgatcat
     2761 aacgcccctt gcgatgattg tctttacagg gctctcttat gtctttttcc gaggtggggg
     2821 aatgctcatg atgatgatgg gaatgtctgt gattacgatt ggaagctcca ttcattctta
     2881 tttttcagat aaaaaatggc ataaagaagc ccagcagcaa aaaatcaagg attatctagc
     2941 ctacttggat accaagtatg tggagctagc aggctatcgt gaggagcaaa tcgaagcact
     3001 gctgtatcat taccctaata tgacgactat tcttgaaatg gcacaaaaaa cagatcgccg
     3061 tatttatgag aaggctccat atcattttga ctttttgacc taccgcttgg ggctaggtga
     3121 tactccagcc agctttcaca ttgattattc agattctgag ctgaccaagc atcatgaaaa
     3181 ggcaaagcaa agggttcaag agctgattgc ttattatcag gtgacagcac aggtgcctat
     3241 ccaaaatgcg attgccagtc caatcggtta tattggagca cgcaaggtcg tgattgagca
     3301 ggttcagcag ctgatgatgc agatcgctac cttccatagc tatcatgatg tacagtttat
     3361 tcctattttt cgagaagaag agctgccatt gtggaattgg agccggtggc tgcctcatac
     3421 taagctaaag gtgctaaata gtcgtggctt tgtttatagt cagcgaacac gtgaccaatt
     3481 gttgacctcg ctttatcagc tgatcaagga gcggcaatta gacagtgagc aggataaggg
     3541 gacagaaaag caatacactc cgcattatat agtgctgatt actgacatga gcctcatgct
     3601 tgaccacaat atcatggaat acatcaatga ggatttgtct catctaggca ttcattatat
     3661 ttttgttgaa gaggtcattg aaagtctccc tgagcatgtc aaaacagtta ttgattatcg
     3721 tggagataag catgctcagc tcattttgca ggaggggctc tacctcaata aggcctttac
     3781 cccacttcaa cccttatcta tgaaggataa ggaggtcttt gctagacata tggcagggat
     3841 taatcacgtt gagaccttac gcaatgcgat tccaaatagt gtgacctttc ttgaaatgta
     3901 tggcgttaac aaggtcgagg agcttaatct cttaaagcgc tggaaggaaa atgaggctta
     3961 tcagacaatg gctgttccgc ttggggtgcg tggtcgtgat gacatcttgt acctaaacct
     4021 tcatgaaaaa gcccatggac cgcatggctt aattgcagga acgactggat ctggtaaatc
     4081 agagctggtt cagtcttata ttttgtcgct ggcggtgaat tatcacccct atgaggttgc
     4141 ctttttgctg attgactaca agggtggtgg tatggccaat ctctttgctg atttaccaca
     4201 tgtcgttgga accattacca acctagatgg caatcaggcc aatagggctt tggtatcgat
     4261 taaggcagag ctgaaaaagc gtcagcggat tttccttgaa aatgatgtca atcatattga
     4321 tcaatacact aagctattca aggaaggacg agttaaggag cccctcccac acctgttaat
     4381 catcagcgat gaatttgcag aattaaaggc caatcagcca gaatttatgg acgagctggt
     4441 ctcaaccgcc cgtattggtc gttctcttgg tgttaagctc attttagcaa cgcaaaagcc
     4501 aagtggtgtc gttaatgacc agatttggtc gaatgcgaag tttaaaattg ccttgaaggt
     4561 tcaagatgtt gcagattctc gtgaggtgat taaaacccca gatgcagcag agattactca
     4621 ggttggtcgt gcttatctcc aggttggaaa caatgaaatt tacgagctgt tccaaagtgc
     4681 ctggtctgga gcagactaca atccaaaagg acgacatacc attcagcatg agacaacggt
     4741 ctatgaaatc acagctaatg gtcaatacca agcgattaac aaggacctta gtggacttga
     4801 caagaagaga gaagcaaaat ccatgccaac agagctagat gcggttgtag cagaggctca
     4861 gcagctcttt gaggacctgc atattccaaa ggtggccagt ccttggctgc cgcccctttc
     4921 agaaaaaatc tatgccagtg atttacagtc cacgcatttc aaggactatt ggggacagac
     4981 acaggacttg cagcctgttt tgattggcta tcaggacatt cctgaacgcc aagagcagtc
     5041 cccactctat tttcatatgg aaaaggctgg gcatatcctc ttagtgtcta gtcctggctt
     5101 tgggaagtcc accttccttc aaggctttgc tttagatgtg atgcgaaagc aaacaccagc
     5161 acaggctcat ttttacctct atgattttgg gacaagtggc ttgattgcgc tttctgattt
     5221 tccacatgtg gcagattact ttaccctaga tgagacagac aagatcatga aatcacttcg
     5281 ttatttaagt gaagaaatca agacccgtaa gcatgcccta tctaaggcta aggcaaccaa
     5341 cctcaatcag tacaatcaat tatccaagga taccttcccg gctctttttg tcatcattga
     5401 tggctttgat agtgtcatgg acgcaccatt tgtagatgct gtctacaatg tcttaaacgt
     5461 tattgcgcgt gatggggctt ccttgggaat gtaccttgtt gtgaccttat caagacttaa
     5521 taccatgagg ctacagctgc agtctaactt taagaccaag ctatccctct tcttgtttga
     5581 taatagtgat ttatcaagtg tggttggtcg ctcaaatatc ccactagatg atatcaaggg
     5641 acgagctatc atgaaacgtg acgacattat ccaatttcag attgccttgc catatagcag
     5701 tgagtactat acagattata tggcggaggt aaaaagagag gtcgaggcga tgagggctgt
     5761 ttatcaaggt gctttgccag cggctattcc aatgctgcca gaaaaggtta caccggatat
     5821 gatagcagcc atgtcagact ctgctcagga ttttgtgatt ggtttggagc gagaggacgt
     5881 tgttcctgct ggctttacct ttaaaaagtc aatactgatg gcctctgata gcccagcctt
     5941 tgtggctaac tattataagc tgcttgattt tcagttgcag cgtctggctg accagtatcg
     6001 tacggttatt ttagatccta gtcagcgtat tgcaaggcaa ttctttgagg atagtcaacg
     6061 ctttagcaca gccttagatg ttggagacac tctaagggct attgtagagg actttaaaaa
     6121 gcgtcttgca gcacctggtc aggattatca aaaatggtta gttgtgattc ctgatattgc
     6181 agctacagcg ctggcagcag ggattagcga ggaagacttt aaacagcttg tgaccgaggg
     6241 cagccagtat ggggtcacgc ttatctttgt cggagcttat caggatctgg tcaataatac
     6301 ctatgataat tttgtgaagc ttgcaaatca gctcattgag caggtctttt taggcatgcg
     6361 gatcagtgac caaagccata cacgatatgc ttatatcagc aatgagcctt cacttagacc
     6421 gacccagggc tatatcctat acccagaagg ctatgacttt attcaattat tagagattta
     6481 gaaaggaaca aagatgtcaa cagttacgat acttccactt ggtagtattg tcattttaaa
     6541 gggcaatact aagaaaatga tgattattgc gcgtgtgatc gcagctccaa tcaaagggga
     6601 ggtttaccgc tttgactatg gtgcctgcct gtatccggag ggcatgatgg gggatagttt
     6661 gatttacttt aatcatgacg atatttttaa gattattcaa gaaggctatg ctgatgatga
     6721 caatgctctg atgttagaga cgatagcaca ggctttagca acaacggaca ttccaaaagg
     6781 agatgtttca gccttaaacg atagaaagac tgttgaggac tagcttatgg ggcaagttga
     6841 ctacaatcat atcaatcagc ttcaacgtca ggttgaccag cacagggcca gtctatcaac
     6901 ggctacagca gagatagcgt caatagacga aaagctagag cgcttgcgtt gtgccaaggc
     6961 ttctgttgga gcgattcaag gagatgttca tcagatcaag gtctctgtga tggctaagag
     7021 ggatcagcct gattggaagg gagaacgcaa ggaccgcttg atgtcgagct gggaggagtt
     7081 ctctcatgac tatcgccact ttcagctgga gctagatgct tattacgatg ccatttgtga
     7141 tacgataaca cgcttggaga atcaaaaata tgagcagcaa gggcttatcg gctggtgtca
     7201 gagcatgatt aatagcttgg gaaatgagat tgaaaagcta tttcatatta gggagggcta
     7261 gcatgtttgg tgttattcaa ttatctgagg ttgtgtttgg ggcgcatgtg ttaagcctga
     7321 ctgctgctaa ggctagcttg tctgatgtca aagctagctt tcccagccat cagtcatcaa
     7381 gtaaggtgct agatctgtat cagtcagagt ttgaagcact ctctcagctt gttgctgcct
     7441 atgctaggct tttggaaaag gatattgcct tgattgccga ggctggtcaa gaattagccc
     7501 taacagataa gcagttggga caagctatag gatttaggtt acaataggag gagggtatgg
     7561 gatataagat tcactttgaa gccatcagtg ccgcccaaca aagcactcaa accacgatca
     7621 gtgcttgggg agaaaggtcg tcttctcttt tatgatgttc aaagcaaggt aaatactttt
     7681 cttgaagttg tcaacgtttc tgaatccaaa agcattgcgc ttgatacctt tgataaattt
     7741 gttagttgct tcaagcttgg cgttagaata aggcagttca atggcattga tgatatagtc
     7801 gttatagcgt ataaaggtgt ttaaagtcgt tttgaaggtg tgattgagat gaggcaaagc
     7861 atcttgactt aacccaaaga agagctctgt cttcttttct tgcaagtgaa aaagaagtca
     7921 ttggtacaga tcataatagc cttttaactc agggattcgt ttgaaaatct tattgagaca
     7981 ttgtctagga gttaatgttt ctctaaaggt cctagagtag aaagtattaa gagatagttt
     8041 ccagttatcc tttagactaa gcttccaata gtatttaaga gcccgatatt caagagcttt
     8101 cttatcaaat ggcttcatga gttgaatgcg agtttgattg agcgctctac tcatgtgcta
     8161 cacaatgtgg aagcgatcga gaacaatttt agcttttggg agtgaactag tccagtggac
     8221 taattcagcc tgagcttaaa aatagaagag cgaagggttt aatgagagga atgtaacttc
     8281 ctgacatatc gacagtaaca actttgccct tatttctagc ttctttggag tacttaaaga
     8341 agtgatttcg aatggttgtt tgacatctgt tattgcgaat gataatgatt ttcttggtgt
     8401 tgaaatcctg agcgataaag gctagtttgc ccttttgata agagaattcg ttccaggaaa
     8461 gcacctcagg taaggtggtg taatcctctt taaagtgaca ttgcttgagc ttatgataga
     8521 cggtagaggt agagatagcg agtttagcag caatatgcgt aaaagcttct ttattgagca
     8581 atagctgaga gatcttctgt ctaactggtt cagagatttg gcaatttttc ttcacgagat
     8641 tggtttcaga gacagctacc ttccgacagg tttgacattg aaacctgctc tttttcaatc
     8701 gaataaggct agggaagcca ccgatttcga tgaaagggat tttagagggc ttctggaagt
     8761 catacttaat ctgagctctc ttacagtgct tacacttagg aggttgatag tccaatgtag
     8821 cgatgacttc gatatgtgta tcatgctgga tagccttatc gaaggtgata ttttgatctt
     8881 taattccgat gagtagtgtg gtatgatgaa tctgttccat aagacacttt ctaatgatgg
     8941 tctggtcgct tttcatgata agccttatgg gactttttgt gtactcaaaa gccctataat
     9001 ctccatagtg gacttaccca ctacagaaat tataaagccc taaaaaccaa tctgaggttg
     9061 ttgcaacagg attggttttt tcttgtgatt gcagatcaga cttttcaaaa gaacaagcac
     9121 attatctcag ctagactggt gcttgatagc tcctgagccc ttgtttgctg tagttgatag
     9181 gactttgctg atggcctagt caggcatatc gtatcaaatt caagtttttt catgtcactg
     9241 tctatagttt gtctgcccta ctttaggtag aatagaggta acttaagaga ggagtttatt
     9301 atggaattaa cgatgctttt gatggtttca gttttcattg cagggctgtt atcattcttt
     9361 tccccttgta tctttccagt tctgccggtg tatttaggca ttttgttaga ttctgatgat
     9421 tctaggtcta ttactatttt tggcaagaaa ctatattggt acggtattgt taagaccctt
     9481 gcttttattt caggtctatc taccattttt atcattttag gctatggggc tggtttactg
     9541 ggtaatattt tatatgctgc ttggtttcgc tacctacttg gtgcctttgt gattttgtta
     9601 ggtattcatc aaatggaaat cgtaaccatt aagaagctgc aatttcaaaa gagcgtagca
     9661 tttcaaaata agaaggaccg caatgctgtt ttaaatgcct ttttgctggg aattaccttt
     9721 agctttggtt ggacgccctg tgttggacca gttcttagct cggtgcttgc cttagcggct
     9781 tcaggtggca gtggggcttg gcagggtggc ttcttgatga ttatttatac cttgggctta
     9841 ggcctaccat ttttactact atcttttgct tctggtattg tgttgaagca ctttaataaa
     9901 ttaaaaccac acattcctct attgaagaag ttaggtggct tacttattgt tataatgggc
     9961 ttactgttga tgacaggaaa tctcaatagt ttatcaggtt tatttgaata aaggagaaga
    10021 aacaatgaaa aaaacaacat ttttaacaac aggcttagca tgtcttgctt tattaactgc
    10081 atgttcggcg aaggataaaa tggccatgaa tgatagtaaa aaagaccata tgaccaggac
    10141 cgatgacaaa tcaaagatga aaaaggatca aaaagacaag atgtcagaca agaaggatat
    10201 gatgtcagat gacaagcaca tgtcagatgc tgacaaggct agtaagaatg atgggcaaat
    10261 ggctccagat tttgaattaa agagcattga tggcaagact tatcgtttgt cagattttaa
    10321 aggtaagaag gtttacttga aattttgggc ctcatggtgt tctatctgct tatcaacctt
    10381 aggtgataca cagtcattag ctacgatgaa ggataaggat tttgaggtct taaccattgt
    10441 ttcacctggt catcagggtg aaaaatccga ggctgatttc aaaaaatggt ttgaaggaac
    10501 agactttaag gatttaccag tcttgctcga tccagatggc aagctgctag aggcttatgg
    10561 tgtgagatct tatccaactg aaatttttgt tggcagtgat ggtgttttag ctaagaagca
    10621 tattggttat gcaaagaaat cagagattga aaaaacctta aaggagatta aataagcaaa
    10681 ggaggctgtc tcatggaaca caaatggaag ttattgctac tcgtttttgg agccttagta
    10741 tttttaggag gtgttttgat ggtctttcaa agaggctacg ctactagcta ccataataat
    10801 caggtcaagc tgcctgccaa agggacgtct cagctcaaga agactgctaa tgccaagctg
    10861 cctgagaaga aaaaggagat ttaccttgca ggaggctgtt tctggggtgt ggaggagtat
    10921 ttttcaaatg ttgatggtgt tctagatgct gtttctggct atgctaatgg tagaggcgac
    10981 acaacctctt atcaattgct gcaccagaca ggacatgctg agacggttca ggttgtgtat
    11041 gatgctaatc ggattagctt aaaggagctt cttttacact actttagaat cattgaccca
    11101 acaagcctca ataagcaggg caatgatcgt ggcagtcagt accgtacagg catttattat
    11161 acggatccat ctgatttgac tactattgat atggtctttc aggaaaaagc ttcggattac
    11221 aaaaagaaaa ttgttgtgga aaaagctccc ctaaagagct ttaccaaggc tgaggaatat
    11281 catcaggatt acctcaagaa aaatcctaat ggctactgcc atattaatgt caacgaggct
    11341 tcatacccag tgattgataa gacaaaatac cctaagccaa gtaaggaaga gattaaaaag
    11401 aagctatcaa aggatgaata tcgtgtgacc caaaacaatg aaactgaaaa agccttttca
    11461 aacaggtact gggattcctt tgaagcaggg atctatgtag atgtggtcac tggtgagccg
    11521 ctgttttctt ccaaggataa atttgaatca ggctgtggct ggccaagctt tagcaggcct
    11581 attagcccag atgtgctacg ctataagaca gacaagagct tcaatatgaa ccgtacagag
    11641 gtgagaagcc gctcaggcaa ttcccattta ggtcatgtct ttaccgatgg tcctaaggat
    11701 cagggtggtc tgcgttattg tattaacagt ttatccattc gatttattcc aaaggctgaa
    11761 atggaagcta aaggctatgg ttacctttta acagcagttg attagaagat tatcctaaga
    11821 tttgttataa taagatgagg aagcacagat ggttgattat agttattaag acctgaagat
    11881 tacttcagtc gatattgcta aatgtgatca ggctcatgcc ctttagtctt gcttaagagg
    11941 tagtagcttt taaaagagtg attacgataa gaggcatttg ctcagagctt gtcctattta
    12001 gctcttgtcg agctatgtgc agagcttgta tgactatggt cactaagcat tagaaatagt
    12061 aggagaaatg gtgtgtactc attacttatt gttgaagacg aataccttgt gcgtcagggt
    12121 attcgttctt tggttgattt tgaccaattt gccatcgatc gtatagcaga ggctgagaat
    12181 ggtcaggtgg cttgggagtt gttccaagaa aatccttatg acattgtttt aacagatatt
    12241 aatatgccaa agcttaacgg cattcaactg gcagagctta taaaggcaag ggctccaaag
    12301 actcatcttg tttttttgac aggttatgat gatttcaatt atgccctatc tgccttaaag
    12361 ctaggggctg atgactacct gctaaagcca ttttccaaat cagatgttga agaaatgctc
    12421 aaaaagctaa agcagaaatt agaaaagctc aaaaaaacag aggcccttca aaaactagtt
    12481 gataagccgc agcaagaagg ctcagaaatt aagctagcta tccaagagcg tttagctgat
    12541 tcaagcctaa cgctaaagag cctatcaagc cagttaggct ttagccctaa ctatctaagt
    12601 gttttaatca aaaaggatct aggtttgcct tttcaggatt acttgattca ggagcgtctt
    12661 aaaaaggcta agctcttatt attaacaacg gatttgaagg tttatgagat agcagagcag
    12721 gttggctttg aggatattaa ttatttttcc cagcgcttta agcagttggt tggaatgaca
    12781 ccaaggcaat ataaaaaagg agaaggccaa tgaagcgcta ccctctttta gtacaattag
    12841 tgagttattt ttttctgatt gtgatttcac taatcactat tctgggagtg atttattatc
    12901 agaccagctc tcataatatc aggcagctca ttgaacgcga aaccagacag agcattcggc
    12961 agagctctca atttattgat gcctacatta agccattaaa ggagacaacc tcagccttag
    13021 ctagccatgc tgagattcag agctttgcta aggcagctaa cagtagtcat caagagcagg
    13081 tgttggcact gatgacaact gtgctgtcga ccaattcaga cctgcgctca gcggttctgg
    13141 tgacaaagga tggtcgtatg gtcacaacca acccaaagct aatcatgact acctcgcatg
    13201 atatgatggc agagccctgg tacaagtcag ctattgaccg caaggccatg ccggtgttga
    13261 cccctgcaag gcagctgtcc tcgcattcta aaaaggattg ggtggtttca gttactcagg
    13321 aggtagttga tgagacaggg aacaatttag gggtgctgcg attggatatt ggctacaata
    13381 ccatcaaatc ctccctagat caattgcagc ttgggcgtag gggctttgcc tttatcgtca
    13441 atgataagca tgaatttgtc tatcactcta aaaataccgt ctatagctca gagcgagaaa
    13501 tggccgcaat gaagccttac cttgctgttg ctgatggcta tacaaagcct aaggattatt
    13561 ttgtttacca aagggtgatt ccagacagtc aatggacctt gattggagtt gcctctttgg
    13621 atcagctgta tcatgtgcag cggcagattt tttggtcctt tttagggacg ggtctgcttg
    13681 caactgtcat ctgtggtctt gggacagtat ttgttctgag aagctggatt ggtcctatca
    13741 ggaggcttca ggctctcatt ttagctattc aaaagggtaa ccgtcagctg cgtgctgagg
    13801 aaattggctc gcctgagtta gctgatttgg cacgtcagtt taacgccatg ctggatcaaa
    13861 ttgatagttt gatgatttca gttgctgaca aggaaaaggc tattgggcag tatcgtctgc
    13921 aagccttagc cagtcaaatt aatcctcatt ttttgtacaa caccttagat actattattt
    13981 ggatggcaga gtttaatgac agccagcgtg tagttgatgt caccaagtct ctggctaagt
    14041 atttccgctt ggccttaaat cagggaaatg aattgattag ccttgctgat gaattggatc
    14101 acgctcgtca gtatttgttt atccaaaagc agcgctatgg tgacaagctg cactatgaga
    14161 tcaaaggtct tgagaaatac caggacttta tgattcctaa gctgattctt cagcccttgg
    14221 ttgaaaacgc tatttatcat ggtattaagg aggttgatag acctggaatg atcagagtaa
    14281 ctgtattaga agctgatcgt catgtgatat tatccgtttg ggataatgga aagggcataa
    14341 gcttagctga tgacagcagt caggccctgc ttgagtgtgg cggtgttggt ttaaaaaatg
    14401 ttgaccagcg cttgaaatta cagtatggtc atctctatag aatggcaatc actagcgagc
    14461 aggctgtttt tactgagatt aagctttatc ttcccaagcc gcttgatggc ctaaatgagc
    14521 tcccctaatc aatctgccct tagtagaaca aggaaaagag aggtttatgt ctttagaatc
    14581 cgattatttt aagcgaaaaa gtcctgtatt tgaggccctt atcccttatg gctttaccca
    14641 agagggtgac acttattgtt atcaggagtc atttatggag ggagatttca aggccttgat
    14701 tacgatcaag tcgtctggtc agctctcagc tagagtgatt gatactgacc ttggggagga
    14761 ctatctcccc ttgagaaatg atagacagca gggagtttat gttggtcagg ttcgtcaagc
    14821 ttatctagag cttcttggac gtttatcagc tgcctgcttt aggtctaccc cttttcagac
    14881 aaggcaggcc aaccaagtgg caacaagcat tagccagcag tggaatgatc cactagatta
    14941 cccctttgaa aaattcccta atattgccac ttatcgtgtt tctggcaagt ggtatgcgat
    15001 ggtattgccc ctgctagccg ataaattagg acaggtgcca aaggtcttac aggggcaaat
    15061 ggttgaggta ttgactgtta gaattgctcc taatcagcta acacacctct tgcagcaacg
    15121 tggtgtttac ccagcctatc atatgtctaa aaagacctgg attagcctat tactagatgg
    15181 tacactagca gatgatcagc tctgggagct agtcacgaaa agtcgtcaat tggctaatcc
    15241 taatggccta gctaacccag atggaccaga ttactgggtg attcctgcta atctcagcta
    15301 ttacgatatt gacgcggaat ttgcagctaa tcctgacatt ctctggacgc aaaaggcttc
    15361 cataaaagct ggagactatg tttttattta tatcactgca ccgaccagat caattcgcta
    15421 tgcctgtcag gtcttgagat cagacattcc taatcaaggc tatcggaaaa atgcgaagat
    15481 taagacctta atgtcgctac gcttgttgca ttgctacgaa gatggtttga tttcccttga
    15541 tttgatgaaa cagtatgggg ttaatgctgt tcgcggtcca agacggttaa gcccacaatt
    15601 agttgcattt ttgaaggaaa aagagtattt taaagatgtg aaacaaaaag aatgataagg
    15661 agagcgggta tgactcaatt tatagcagat cagagctttt gggaattatt tcctgatgct
    15721 aagctaggtg ttttgttgct caggaactat gacaatcagg aagactcccc acaagaggtc
    15781 aagcaattat tggcagacag ccatgacata gctaagcagt atttgactga agagtcgttt
    15841 agtgacaatg agatcattca ggtctatcgt caagcctatc agcgttttaa gacaaaaaag
    15901 ggagccagat ccagtattga ggccctccta aagagggtgg caaatggtca agtcctatcc
    15961 tccattaacc ctctggtgga tatttacaat acagccagtc taaggtttgg tctgccagtt
    16021 ggcgcagaag atagtgattg ctttgtaggt gacttacgcc tgacgttaac agagggaggc
    16081 gatgagtttt acctcattgg tgattctaaa aacagtccaa ctctgccaaa tgagctctgc
    16141 tacaaggacg atgctggtgc tgtttgccgc tgcctaaact ggcgcgatgg tgaaaggaca
    16201 atgattaccg atcgcactaa aaatgccttt ttagtcattg aagcattaga tagcaagacc
    16261 caagcaagac tacaggacgc ccttaagttt atcgaagaca aggctaagtg ctacctgaag
    16321 gcagaaacag cactatatac gctggatcaa gcctcaccaa gtatcacgtt ttaatcaaaa
    16381 aaagctagga agccagtatt cctagttttt tcagttgttc aggtgctttt atttggtgtt
    16441 gtcgagggag atttccttat agctgcaaga tatgacatga cagggaaaca gtttttgctt
    16501 gtttgatcta atcaagcgat taataaaagc ttttaagctg ttggttatgc taaagggctt
    16561 tcttaatcct atcagagaac tttaaaaaat agtataatgt agttaactta tgatgatagc
    16621 taaggaggtc agcatggagt tatttgacaa ggttgatgat acgttaaagg ctttagcgat
    16681 tgactaccag ctggttgagc atgagccagc tttaaccaca gagcaggcag accagttcat
    16741 agagggcatt gaaggggtta gaaccaagac aatgttttta acgaccagga aaaagaacca
    16801 tttttatctg atcattatgg atgatactaa gagactggat atgaatcgct tcaaggagct
    16861 tgttggagaa aagcagatta aaatggcatc agcagaatgc ttgcttgcca agatgcagct
    16921 gccaccagga gttgtttctc cttttggtct tttaaacaac gaggataagg atattcaggt
    16981 ttacgttgat aaagctattg ctcacgaagc tagaatgagc tttcacccaa ataccaatga
    17041 caaaaccatc tttattcaaa cagatgacct ctttaagttt ctagcggcta taggttacgc
    17101 ggtcaatatc gtggatctat agctaaattc aaggttcttc tagcggttct tgctcacatc
    17161 agttcacaaa gctggtggcc tagccaatcc agggcaaaca aaaagcacaa tagcctttct
    17221 tgactactga gaatagccag tagacccttg tgtcatatgc ttatctggta tttgagctta
    17281 aatctcaagg cttttaagta gaggatcaaa caaagaaaac gaccagcaga ccttgcgtga
    17341 tgactgatta tcaagtctgg taggagctaa aatcagtcat ggtcttgagg cctaaaacgt
    17401 cccatttgtc gctcctgttg ctagggcatt agttgacatg tatacccacg actaaccaag
    17461 ccgaggagag ctgtcgctcc cttctcagga gcgtggattg aaatgcaaaa gggatctgat
    17521 agacatttct gcttttaaag ctagtccatc aaaaaaacgc atgacaccac tgtagtggga
    17581 catcatgcgt ttttgctaag ctaaagtgat ttgacgcttc ctttgaaagg gttatttatt
    17641 gctgaagaaa aagggtggtg tgtaatggct caggatttca aagcaagctt tggcctgctc
    17701 attgtcctca cagataatca gacaggtatc atcaccacag atagtggcta cgatttctga
    17761 gatttgcata gcatcaagga tagagccaaa ggattgtgcc agccctggta aggtttttaa
    17821 aataatctga tgctgaacaa ccctgagcat gacaagggcg tcctccatat aaaagcgcaa
    17881 acgatgctcc caacgcgtct gagaaatggc cagcgcttca taatgcgtgt cattaccagt
    17941 tgtaaccttg acaaggttaa gctctttcat atcacgtgat aaggttgcct gtgtgatgct
    18001 tatcccattt tttcgtaagc gttcctgtaa ttcctgctgt gtgtgaatag ttgtttcaga
    18061 aattagagat cgaattaatt gatgacgtgt ttctttttta ttcatttctt ataatattcc
    18121 cctaatgatt agtaacattc agagtataac aaaaagatgg cagtgtgtaa agttttagat
    18181 gaaccgctta caaaaatagc ctttttatgt taaaataaaa cgggtgctta gaaaaggaga
    18241 tttgcgtgat tcgaagagaa gattatcaat accttagaaa acttgatgat ttctgtcatt
    18301 tttcaattga acaatttgac aagattgtcg gccaaatgga atttagacaa gctaaaaagg
    18361 atcatatgtt attttttgaa ggtgataaga gggacagact ctttttagtg acctcaggtt
    18421 attttaagat tgagcagtca gatcggacag gaacctttac ctatactgat ttcatacgac
    18481 atgggacaat ttttccctac ggggggctgt ttacagatga ctactatcat ttttcggtgg
    18541 ttgcgatgac agatgtcacc tacttttatt tcccgactga tttgtttgag gactattcct
    18601 tgcacaatca gcagcagatg aagcatctct acagtaaaat gtcgtccttg ctggagcttc
    18661 atgagctcaa ggtgcgcaat ctcatcacct ccagtgcaag ctcacgtgtg attcaatcct
    18721 tggctatttt actggttgaa atgggaaagg atagcgatac tctgcctttt cagctgacga
    18781 ctactgacat tgcacaaatg agtggaacaa ccagagaaac cgttagtcat gtctttagag
    18841 atttgaaaaa ggaaggcttg attgcagtca aggggaaata cctcacctac ctagataaaa
    18901 actattttct gcagtacaca acctaagatc aagtcaaaag gcttcgctta aaaa
//
LOCUS       DARYXS010000034        18627 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.034, whole genome shotgun sequence.
ACCESSION   DARYXS010000034 DARYXS010000000
VERSION     DARYXS010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18627
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.034"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..650)
                     /locus_tag="TV193_000977"
     CDS             complement(<1..650)
                     /locus_tag="TV193_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HEL1513184.1"
                     /translation="MDEIKLYENKEIRSIWDEEKEEWYFSVVDVVGVLTEQENVRGAS
                     TYWAVLKKRLKEEGNELLTICKQLKMKATDGKMRLTDVADMQGIFRIIQSIPSPKAEP
                     FKLWLAEVGKERIDEIIDPELTIDRALETYLKKGYTREWINQRLQAIQVRKELTDAWD
                     DHGIQKGKEYAILTDEITKAWSGMTTRGYKNLKGLKKENLRDNMTTLEIVLNMLAEA"
     gene            complement(746..1711)
                     /locus_tag="TV193_000978"
     CDS             complement(746..1711)
                     /locus_tag="TV193_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL1513185.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEEIIEKALEIYFKEYIGQ"
     gene            complement(1704..2480)
                     /locus_tag="TV193_000979"
     CDS             complement(1704..2480)
                     /locus_tag="TV193_000979"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL1513186.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            complement(2632..3795)
                     /locus_tag="TV193_000980"
                     /pseudo
     CDS             complement(2632..3795)
                     /locus_tag="TV193_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(3797..5518)
                     /locus_tag="TV193_000981"
     CDS             complement(3797..5518)
                     /locus_tag="TV193_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513187.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            5967..7973
                     /locus_tag="TV193_000982"
     CDS             5967..7973
                     /locus_tag="TV193_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL1513188.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            complement(8164..8574)
                     /locus_tag="TV193_000983"
     CDS             complement(8164..8574)
                     /locus_tag="TV193_000983"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1513189.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(8706..10055)
                     /gene="gdhA"
                     /locus_tag="TV193_000984"
     CDS             complement(8706..10055)
                     /gene="gdhA"
                     /locus_tag="TV193_000984"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL1513190.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            complement(10196..11972)
                     /locus_tag="TV193_000985"
                     /pseudo
     CDS             complement(10196..11972)
                     /locus_tag="TV193_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(11972..13717)
                     /locus_tag="TV193_000986"
     CDS             complement(11972..13717)
                     /locus_tag="TV193_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513191.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISISKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            complement(13822..15689)
                     /locus_tag="TV193_000987"
                     /pseudo
     CDS             complement(13822..15689)
                     /locus_tag="TV193_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            complement(15682..16893)
                     /locus_tag="TV193_000988"
     CDS             complement(15682..16893)
                     /locus_tag="TV193_000988"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL1513192.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            complement(16993..17841)
                     /locus_tag="TV193_000989"
     CDS             complement(16993..17841)
                     /locus_tag="TV193_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1513193.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            complement(17841..18221)
                     /locus_tag="TV193_000990"
     CDS             complement(17841..18221)
                     /locus_tag="TV193_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL1513194.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            complement(18426..>18627)
                     /locus_tag="TV193_000991"
     CDS             complement(18426..>18627)
                     /locus_tag="TV193_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEL1513195.1"
                     /translation="SPDNGMMESFFGILKSEMFYGFEKSYHSLDELEQAITEYIFYYN
                     NKRIKTKLKGLSPVQYRTKSFQ"
BASE COUNT         5434 a         4338 c         3305 g         5550 t
ORIGIN      
        1 gcttctgcaa gcatattaag aactatttca agagtggtca tattatccct tagattttcc
       61 tttttcaaac ccttcagatt tttataacct cttgttgtca ttccggacca tgctttggtg
      121 atttcatcag taagaattgc gtattctttg cctttttgta tcccatggtc atcccaagca
      181 tcagtcagtt cttttcttac ctgaatggct tgaagtcttt gatttatcca ctcacgtgta
      241 tatcccttct ttagataagt ttctaaggct ctgtcaatcg taagttcagg atcgataatt
      301 tcatcaattc gttcttttcc aacctcagca agccataact taaaaggttc tgctttaggg
      361 gatgggatgg actggataat acggaatatt ccttgcatat ctgctacatc agttaaacgc
      421 atttttccat ctgttgcttt cattttcaac tgcttacaaa ttgtaagcag ttcatttcct
      481 tcttctttta atctcttttt tagtacagcc caataggtac tagcacctct tacgttttct
      541 tgttctgtca aaactccaac tacatcgact actgaaaaat accactcttc tttttcttcg
      601 tcccaaatgg agcgtatctc tttattttca tacaatttta tttcgtccat tctgacacct
      661 gcctctttta tatcttatcc tgttaaacag gtcttttccc tttttaatac cttatattat
      721 accttaaatt tataattttg tcttttcact gaccaatata ttccttaaag taaatttcca
      781 atgctttttc tataatttct tctacatctt ctttcctttc atcatgaaaa aactttttat
      841 agacactctg agatagtttg atattctgat acttttttac cttcgttttt ttcaagttca
      901 gcaagtatgt tataaccatc tcttgattca gatcttcttg tctgttcatc agatggagtg
      961 ctttggcatc gcttggtttt aaacttagtt ccaattcttc gcacttctga tacagatatt
     1021 cctgtatttc tttggaaaga taggataaat ctactgccat cgtcaaacct attttatctt
     1081 catccacatc ttttttccaa gacttagata attcatttaa tcttaggtac cttgcaatag
     1141 atgcccctga aagattatat tcttttccaa gtgtttttct gctgtctatt ttatcttcct
     1201 ctttactttc cttttctata attccctgat ctaaattgtt tatctccttt tgcaaatcat
     1261 ttctcttgcc ctgacttgct attttttcat atctcatttt aagaacaagg gctttttccg
     1321 tcggcagtaa atcggagaaa gaacgctgta taaggtttgt ttcaattaca taggtatagg
     1381 cttctttatc cgttagattt tctttaacaa tacaaggaat actttttatt tttgtaattc
     1441 ttgctgcatt tactctattg tgtccggaaa gtatttcata gttgttatct tttttcaaga
     1501 cgataattgg attaagaact ccgttttcct taatgctctc taccatatcg tctaatctct
     1561 tacctgtata taaagtaaac ggatgattat gataattttc aagcaaatca agttctatat
     1621 tctgtatatt tccttgttcc aaggcatttc catcatcaag caaaaaatct acggcatcgg
     1681 tgatttctct ctttagaagt tttttactca tagcagatct cctttgccag attgtcatag
     1741 gcaatgtcta cactactgcc ttttgcatat ttttttatgc tttgcccgct atagatggct
     1801 tccccaactt taactgtttt cggaattttg gtttgaaaga ccttgatttt cttttggaac
     1861 atttcttcta cttgctccat cagtgttttg gacagattgg ttctattctc acacatggtt
     1921 agtaaaatcc cctgcacttt cagtttcgga ttcactctct tttttatttt ttgaacagtt
     1981 tttaaaagtt cattgattcc aacaactgcg aacagctgtg tatccgctac tataaggaca
     2041 ctgtctgagg cacaaagagc atttatagtc aaaacactaa gtgatggtga tgtatctatg
     2101 agaatatagt cataattctc ttttaccctc ctaataattt ccgataatat acgttcactt
     2161 cctgtttctg ctctcatttg tgtttcaacg gcggataaga aaatgcttga ggggataata
     2221 tctatctcat cataagattt ggtatagccc tctaccaaat agctttcttc ttcctccagt
     2281 tctaccatta acaaatgccc tatggttttt atattttctg tatttcccat atcaaaacat
     2341 cttgtaagat tagcttgtgg atcaaggtca atgactaata cttttttccc cagttctttt
     2401 agtgaatagg caaggtttag agttgtagtt gtttttccaa ctccgccttt tcgattggct
     2461 atggttatca cttctgccat aaagtccctc cttcttctct atacagagat ttcattttat
     2521 gctatacttt tatataattt tagatataaa aaaagatgat agcctcaatc catcatcaag
     2581 tttaaaagtt ttgcggaagc ctttaaccat tgattttact tggatttatt gtactatcat
     2641 cattatagca ttgtccccag agccagtatg ccctactagg gcaaccgtct cccctttatc
     2701 agcatgaatg gtaatatcag ataaaactgt cttgccattt tcgtaagcaa aatacacctt
     2761 ggtaaaatcc acagtaccat ctgttagctc aattgctcgt gctttatccg gctctgtctg
     2821 cgcctcaagc agcttcatta ggcgcgttcc tgtcgctgtt gagcgctgaa tattaggtag
     2881 ctgcctaacc agcatactta ataaatcaaa caagcgcagc aaataattga cgtaaataaa
     2941 gagcttacca actgtgatgc ctgatctccc ctgcaagaac tggtaaccaa taacagccaa
     3001 aatagcggca atcatgccat actttaccaa ttccgtcagg gtccatgaag caactgactc
     3061 tgcaaaaata atcctatcat cagctgtttt catctggtgg atctgctctt caaattcctc
     3121 taagatcgta tcctcttgat gataaagctg aataatagaa acaccattca tggtttcgtt
     3181 gacttgtgtg ttgacagcgc tcctagcctg ataaaaatcc ttcattggct ggtcagtcaa
     3241 gcttttatac agccattgca tgccataaaa gagtggcata ataagcagca acagcaagcc
     3301 tgacttcaca tcaaggtaaa tcatcaccac ataaataaaa ataatttgtg aaagactgac
     3361 aataatttga gacaaaaggt tatcataaaa ttgattcttc agggtttcag tatcattaac
     3421 aatcctagtt gcaatctttc ctgcaggctg atgatcaaaa taagctatcg gcagcctctg
     3481 catgacatca aaggctcgat tacgaagatt agcaacgatc ctattagagg aataaaccag
     3541 cattcgataa gagatataac gcaaaactgc tgttatcaca attaacagca aatacagcag
     3601 gagcaagcgc tgaaagcctt caatcggtac ctcttttcct ctagctatcg gagtcaagta
     3661 atgatcaatc gtttgttgca acaataaggg agccatctga cctccagctg ttgccactag
     3721 caaaaagcct attgccaggg aaaaagccaa ggtcacagct ttaatttctt ttattaattt
     3781 tataaatagg gtcatcttaa acctcctgag cctgctgacg ctggtactgt tcataatacc
     3841 agcccttctg agctaaaagt tgttggggct gaccttcctc tactatctgc ccctgatcca
     3901 gaacaataac ccaatcggca tgctgaatcg cagacaagcg atggctaaca ataagtgttg
     3961 tctttccctt tctttcgtct tgaatgtgtc gaataatatc agtctctgtt ctagcatcaa
     4021 ctgccgacag ggaatcatct aaaatcagca aatctggctg ggacaaaaag gctctggcaa
     4081 tcgaaatacg ctgcttttga cctcctgaaa tagacagacc acgctctcca atctcagtat
     4141 ccaagccctt tgccattcct tgaacatcac gcgtaaaggc cgcagtttca atcgcctcca
     4201 agatttcctc agttgtagct gcctttttcc ccatcgcaat gttttgagca accgtttttg
     4261 aaaacaggat atgctcctgt ggcacatagc caatttgacg ctcaagtgat tgacgcttat
     4321 aatccaagac actacgatga ttaatcatca gctgcccctg cccaagaggg tattgtctca
     4381 aaaactgcct gacaagggtt gttttaccag agcctgtttt accaacaatc cctaaggttt
     4441 gtcccttttt cagggttaaa ttgatctttt ctaagctagg cctagaacta ttggcatagg
     4501 taaagctata gtctataaaa gcaatctgat caaagctctc taactcaagc tggccatcag
     4561 gctccatatc atcacttgtt tcgatgagtt cattaatctt accaaaagag gtctttcctg
     4621 tctgataaac caaaataaag tctgacagca tgccaaaggg ctccaccaaa gacaccagat
     4681 aaagctgcag cgcaatgact tgaccaagtg ttacctctga gcttgctatg agctgtaggc
     4741 ctaccattaa aatgattact gtactaatgg caatcatgac gctgtaaaga ggaaagtaca
     4801 aggcacgata cttggccacc tgattccatt tatctgccaa attctgagtc ttttgagcaa
     4861 aatgaagtgc caaataatct tttttactgt aagcacgcat cactctaatg ccctcaacgg
     4921 tttctagtac ctcatcacta aggcttgaaa tcgcctcacg cgcctcttca accaaatgct
     4981 cttgcttttt cgtcacacca tagatcatca ccatcataag caaaatcggt actattccta
     5041 tcaaggtcat tttccaagaa atcaaaaaca tggtcggaat aataaaagca atcataccac
     5101 cagcatatag gataatcatc aagccatagc cgataaggtc cataagtgct tcgacatctg
     5161 ttgaaaaacg cgtgatcatg tcacctgagc gaaatttctc ataaaaaggc gttctcataa
     5221 aaacaagctt tcgaaaggca cgctgctgaa tatcaaactt aaaatgaact gcctcctgaa
     5281 ataaatgaag atgccacaaa taagcaaccc cataagacac tactgccgta gccaaaagaa
     5341 tgataacatg cctcaccaat gcccctgagc ttagctgatg ccttgacatc aaatcaacca
     5401 agtcttgaat aacccttgtt ggtatcacaa gtgaggcatc atatatcact aaagtcattg
     5461 caataaggat ataaatccat ttcttttgct taatatgttg aacaattaag gtcagcatca
     5521 tatcctccat ttctgaacta acctatttca agctgtctta aaataggatt tttgcacaca
     5581 aaaagcccgc aataagatat ccttcctacc gcgggctcta ctatttctat ttagtgaaac
     5641 taaaagaaac taactgtttt ggttagaaag gagactatcg taataatggt taaatagttg
     5701 aatgaaacgg atcattatta atttctcctt tcttttaatc tgcctaacat cttatcatag
     5761 aatactgggc ttgtaaagcc ttttttggat agttcttcta tttttttaca aaaaacgctt
     5821 ccaatgtttg cattttaaac gttttcagtg attagcaaac gctatcgttg aatttttgtt
     5881 agctttttta ttaatttttg ttgaattctc atttaaataa tagtacactt aacttgtgac
     5941 aatactttaa acttttagga gcgtttatga aaaagcattt tgttttaaaa agtagtgttc
     6001 ttggtgtctt tgccggagtt tctatgctag taaccggcgt gcaggccgat caggtagacg
     6061 tgcaatttct tggtgtcaat gactttcatg gtgccttaga cacaaccggc tctgcctaca
     6121 tgccagaagg aaaggtatct aacgctggta ccgcagcaca attagctgct tatctggacg
     6181 atgcagaggc tgactttaag caaacaagcc cagatgggac aagcattcgt gttcaaccag
     6241 gagatatggt cggagctagt cctgctaatt ctggactatt acaggacgag ccaacggtta
     6301 aggtattcaa ccagatgggc tttgaatacg gaacccttgg gaatcacgaa ttcgatgagg
     6361 gcttagctga attcaaccgt atcatgacag gcactgcacc tgctgaagac tcagctatca
     6421 acgacattac taagcaatac gagcatgaag cttcaaatca aacccttgtc attgcaaatg
     6481 tcgttgacaa ggagaccaac acgattcctt ttggctggaa gccttatgct gtcaaagaag
     6541 tcccagttaa tgataagtca gtcaaggtgg gctttatcgg tgttgtgaca acagaaattc
     6601 caaaccttgt cctaaaacaa aattatgaac aatatgatta cctagactct gcagaaacca
     6661 tcgttaaata tgctaaagag ctccaagagc agcaggtcaa tgcgattgtt gtcctagctc
     6721 atatcccagc aacaagtgat aacggggtag ttcatgatga gatggcagca gttatggaaa
     6781 aggttaacca gctttatcct gagcatagtg tggatattgt ctttgctggt cacaaccacc
     6841 aatacaccaa cggtaccatt ggcacaacac gtgtcgttca ggctgtttca caggggaaag
     6901 cctatgcaga tgttcgtgga acactagaca ctgacctcaa tgattttgta gccactcctg
     6961 aagcaaaggt cattgccgtt gctcctggca taaaaacagg caatgccgac attcaagcca
     7021 ttgttgatca agccaatgac attgtcaaaa ccgttaccga gctaaagatc ggtacagcag
     7081 ctacctcttc aacgatttct aaaacagaaa acgaagacaa ggaatctcct gttggcaatt
     7141 tgataacaac tgcccaatta accattggta gaaaaacctt ccctcatgtt gattttgcca
     7201 tgacaaataa tggcggtatt cgcgctgact tggtggtcaa agaggatcaa accattacct
     7261 ggggagctgc acaggctgtt caaccatttg gcaatattct tcaggtcgtt caaatgactg
     7321 gccaacaaat ctatgatgtc ttgaaccaac aatacgatga agaccaaaaa tacttccttc
     7381 aaatgtctgg actcaaatac acttatacag ctaatgaggc taacgatcct tcaacaccgt
     7441 ttaaggtagt aaaggcttat aaagataatg gtgaagaaat tgatccagca gctcaataca
     7501 ccctaatcat caacgacttc ctatatggcg gtggtgatgg cttctccgtc tttaaggacg
     7561 ctaagctact aggagccatt aatcctgata ctgaggtctt tatcgaatac atcaaggacc
     7621 ttgaagcagc tggaaagact gtaagtgctg gtattaacgg tgtgaaaacc tatgtcactg
     7681 ccagtcttga aggctctact caaagtgatc ataccggcaa gcacgagatc atcaaccgcg
     7741 tctttaagaa tcgtgagggc aaggtgcttg ctactgagct tgtctctgac ctatttacgc
     7801 ctgctcaaaa tgctaatcct gccacaagca tcaagcctct agcagctaaa aagcaagcta
     7861 atgctgcctt accagcaaca ggaacaagcc agcattctgc tgctgccatg acaatcctag
     7921 gactactaac cttaactggt actagccttt tcaagaaaaa ggaaggccaa taaaatcgtc
     7981 ctagccataa cagcaataac cgactgtatc ttaagcatac agccggtttt ctgatttatg
     8041 tgacgtttat ttgtttcgca cctgttgagc aagacaaata aaccacccat ctatggactg
     8101 ccctcattcg ttagattttc tgtctaactt ttggggtgca gttcactaac gggtggtcat
     8161 gatttaaatc aatatgccct ccagatgatc cagctcatgc tggcagattt gtgcaggcag
     8221 gcctgtcaat ctcagggatt tcttgtgcca atgtgcatca aggtaatcaa ccttgatctc
     8281 ctgataacgc tttgtcttac gttggccgat tagtgatagg caggattcct ctgcctcaaa
     8341 cgcttcacgc ttagcaatta atacaggatt aaacatcacc aaatccacaa agcccatgct
     8401 aataataata accctcttgt tttcccctat catattagca gccagcccca ggcagctatc
     8461 acgataataa gctaaggtat cctgcaggtc ttgaccaatc caaaggtcct ttttcgttgc
     8521 tggctgtgct ttttgctgca agaaaaaggt gtccttcacg atttttttga tcatcagctt
     8581 ctccttgatt cattgctcta atcggcatgc attgtctaga tgaccgatcg tatatcttaa
     8641 cgtcattgag ctaagattaa tgtgctaacc ctactgatat attcagcata taccagccac
     8701 agctcttaaa cgattccctg tgctgacatg gcctgagcaa ctttgagaaa gcctgcaata
     8761 ttagctccca ccactaggtt gccttcttga ccacattcct tggcggcagc ggctgctttt
     8821 tgataaatag ccttcatgat gtcatacaat cgatgatcca cctcttcaaa ggtccatgcg
     8881 gtacgtccgc tattttgtgc catttccagc gcagaaactg ctacaccgcc agcatttgct
     8941 gctttagcag gtccaaaaag aaccccagcc tgctgaaatt gctcaatagc ctctaaggtt
     9001 gagggcatgt tagccccttc gacaacagct ttaaccccat gctcaatcaa ggctttagca
     9061 tctgcctctt gtagctcatt ttgagtcgca catggaaagg caaggtctgc cttaatagtc
     9121 cagatggatc cctcaccagc cggtgtaaac acagcagccg ggtgactctc tagataggtc
     9181 ttgatacgct cacgcttcac ttccttgatt tgctttaggg tctcaagatc aatgccctta
     9241 tcatcataaa cgtaaccaga ggaatccgac actgctaata ccttaacacc taaggcctgc
     9301 aatttttccg ttgcgtaaat ggcaacattt cctgatccag atacaatagc tgttttacca
     9361 gccaagtcct gccccttagc cgccagcatt tgctgagcaa aataaaccac accatagcct
     9421 gtggcctctg tgcgagccaa agagccacca taagctaagc cttttcctgt caacacacca
     9481 ttcttaaagc cattaagacg cttatattgc ccaaataaat agccaatttc gcgagcccct
     9541 acaccaatat caccagcagg aacatcaagg tcaggtccaa tatgcctttg cagctctgtc
     9601 ataaagcttt gtgtgaagcg catgatttct aggtctgatt tgcctttagg atcaaaattt
     9661 gatcctcctt ttcctcctcc aataggctga ccagtcagag catttttgaa aatctgctca
     9721 aagccaagaa atttaactat agactggtta acagaagggt gaaagcgaag ccctccctta
     9781 tatggaccga tagctgatga aaattgcacg cggtagccac gattaacttg gaccctgccc
     9841 tggtcatcaa cccaaggcac cctaaaggaa atcacacgct caggctcaac caagcgctct
     9901 aatagatttt cctcaatata attagggtat ttttcaaaaa caggaatcaa ggaatcaaat
     9961 acctccttga ccgcctgaag aaattcagtc tcatgcggat tatccctttt gaccttatca
    10021 aaaacactgg ctacatagtc ttttgctgat accattatat atcctctcgc ttcttcattc
    10081 tattttaagt atagtcaata ttataaattt tctgaatttt gatgtcaagc ttttactatg
    10141 atctaaagca aattaaaaga gccttggaac gattcattcc aagaccctaa gctttttaag
    10201 actgactggt cttaaattgg ctatgataaa gctcataata gaagccctta gcagctaata
    10261 ggctgtcatg attcccctgc tcgataatct gaccatcttt tagaactaaa atcttatccg
    10321 cctcttgaat ggttgataag cggtgagcaa taacaaagct agtcctgcca accattaatc
    10381 gcttcatcgc cttttgaatc aaaagctcta aacgtgtatc aacagacgag gtggcctcat
    10441 ctaggattag cagctttgga tctgctaaga gagctcgagc aatggtcagc agctgctttt
    10501 gccccaggga aatattgcta gattcctgat tcatcaccat atgatagcca cctggcaatg
    10561 tcctaatgaa atgatcaaca ttggcagcct tagcagcctc aattatttgt tcatcagtcg
    10621 cctctaaatg accaaagcgc aagttttcct gaatgctgcc ctcaaagagc caagcgtcct
    10681 gcagcaccat accaaactga cgcctatagg cttgacgtga caactgacga atgtcctgac
    10741 catcaactgt gatagagccc tcattcacat cataaaaccg cattaataaa ttaatcaggg
    10801 tggtcttgcc ggctcctgtc ggaccaacga tagctaccat ctcaccaggc ttaacctcta
    10861 aattgaaatt tctaatcaga ggattgtctg ctgtatagct aaaatcaacc tgattaaagg
    10921 acacctgacc tgttaaatca tgttctaaat gctcttgggc aatagtcaat tcatctgcct
    10981 catcaagcac tgcaaagata cgttctaagg atgacttggc actttgcagt ggaccagcca
    11041 gctgtgttat ggtctgaata ggctgactga tttgccaaat gtactgaaca aaggcttgca
    11101 tgtttgttcc cgattgtcag gcggcctgct atcacctgta agccagcgat taaggcaaca
    11161 atcatgtaaa cagaatctga aataaaatgc agaactggca tcatgatccc agaaataaag
    11221 ctggccttaa agcctacttc ttgtaatcgc tcagtgatct ggtgaaattc ctcctttgag
    11281 gcttcttcac gaccatacag ttttaaaata ttaaagccgg tcaaattttc ctgcacaaag
    11341 ccattcattt ctcccaaaat attagcctgc gctttaaaat aaggctgtga tttttttaaa
    11401 acaaatcgag aagcagcata tatcaacggg atagcgataa tcacaacaga ggctaggggg
    11461 gcattaatat acaagaccat gccaaccacc aaaataaggg taaaaaaggc gttaacaatc
    11521 tgtaaaaagg actgctgtaa ggcattagag actgtctcaa catcagaggt aaaccggcct
    11581 agcatatcgc cgaactgatg cttatcaaaa taagacacag ggatacgatt aattttttga
    11641 ctgaggtctc gacgaagatc acaaatgctt gattgcacag cccttgtcat aaaatagttt
    11701 gaaccataag agcctaactc gtaaacaagg gccctaatga tatagagagc taaaagaaag
    11761 gcgatatagg ttttattaat gcctgcacca gagactccct ttgctatgtc taataggttt
    11821 gcagatagct ctgttatcac caagccaaga acaaagggct ctaagacact catcacagca
    11881 ctgactattt ttaaaataat ggcagttatt agtgagagcc tataggcact aaggtaggtc
    11941 caaattcttc taaacacatg cttttcagtc attaatcccc ctcctctttt gtcatgtctt
    12001 ccttgtttag ctgagaattg gcaatttcac gatagatggc attgcttgta agcaattcct
    12061 catgtgtacc tcggccaaca atttctccct gatccaagac aatgatttga tcagcatcca
    12121 taatcgtgcc caccctttga gccacaatta agaccgttgc atcttgtgtc acctctttca
    12181 gccgtctgcg taattcagca tctgtcttgt aatctagggc agaaaaggaa tcgtcaaaga
    12241 tatagatgtc tggctgcttg accactgctc tggcaataga caggcgctgc ttttgccctc
    12301 ctgatagatt actgccggcc tcagctagat gggtttgata gcccttttca cgactggtaa
    12361 taaagtcctt cgcttgggaa acctctgttg cctgctcaag ctcactgtgg ctggcatctg
    12421 acttaccata ttttaggttt tcctcaatgg ttcctgtaaa tagcagggct ttttgaggaa
    12481 taaagccgat tttagaacgc agcgctttta attgataatc cctgacatca atgccatcaa
    12541 ccaagattct ccctaaggtc acgtcataaa atcgtgggat cagattaacc aaagatgatt
    12601 ttcctgaacc tgtcgagccg ataaaagcaa tggtctctcc aggcctagtc ttaaatgaga
    12661 tgttatgtaa aactggactt tccgtttcac ccggataggc aaaggtcacg ttatcaaatt
    12721 ctagataacc acgtgttgtg aacgctgtta taccatcttc atttttagaa atcgaaatcg
    12781 gcatatccag cacttccttg atacgcttgc ttgacactgc tgttttaggg tacatggtaa
    12841 agaggttggc aaacattaaa aatgaaaaaa gagcatgaaa gctatattcg ataaaggcca
    12901 ccaaatcacc aatcttaaac tgcccccttg ccaagggatc caaggcaaac cagacgatcc
    12961 ccacaatcat agcaatgata atttgcacaa ataagggctc tgttaagcct gtcaaggtaa
    13021 atagtcgctt tgagattcca gaatagtgat cattgcgctt attgaagcgc tcttcttgaa
    13081 agtcttctct tgcaaaggct cgaataactc tcagacctgt caggttttca cgcaccaatt
    13141 ggttaatacg atcaaggctc tcctgctgct tttctgataa gggtcttgtc tttatcgcaa
    13201 cataaagcac cacaataact aaaaaaggca tggcaacagc cacaatccaa gccaatgatg
    13261 gactggttaa aaagatcatc accactgaaa agatcatcat caaaggagtt acgacaccca
    13321 gcctcaagga catttcagca aattgcatca aaacaaaggc atcatttgtt atccgagtaa
    13381 ccagggaggc tatgccaatt ttttcatatt ccgaatgcga ataatcctgc aagcagctat
    13441 acatgtcatt acgtaaatcc ttgatcatgt tggtggttag cttacccgaa gcataggata
    13501 aaatcacccg tccaatgaca cctaaaagta cgataataaa catcatcaga gcccaaaaat
    13561 aaagagccct ttgatcctgc tgcataacgc cttgatcaat catacgagcc aatattgttg
    13621 gtagccccag attgaccaga acaaataaca agccacccac aatatcgaaa caaatccatt
    13681 taggtcttgt ttttaaatag gaccaaatta aagccattca tttcctccca aataatagtg
    13741 atatgaaaag aagcgcaagc tagcacttct ttttgtctat aactagttta acacaaaaat
    13801 atgaaattga cacataatta attattcttc taattcgctt aggtaatcaa agcgctcata
    13861 ggcttcaagc agctcaagat tccgctgatc cagctccttt tgatattgtg ccaattggtc
    13921 gtaatcactt gccgctctga gcatttgctc ctcaatagta gctatttgtt gctcgatagc
    13981 agctagcttt tcttcaatag ctgcccattc ctttttctca agataggaca ttctcttttt
    14041 agaggtgacc tgatggtcag tgccagcttt ttgctcactg acagcaggct ctatgacctc
    14101 tgcttcaaaa gccttttcat ctaaatagtc gctatagtta ccatagtatt ctctgatagc
    14161 tccatgctca aaagccaata cttttgttgc aaccttatcc aagaaatacc gatcatgact
    14221 cactgtaatg accggaccag caaattgagc taaaaaatgc tccaacactg tcaaggttgc
    14281 aatatccaaa tcattggtcg gctcatccag cagcaggacg ttgggctttt cgatcaagag
    14341 ctttagcaaa tacagtcttt tttctccccg cctgatagct tagcgattaa ggagccatga
    14401 ctagaacgcg gaaaaagaaa ttgctccaaa agctcactga tgctagtggt gccaacactg
    14461 gtcttgacct catctgccac ctcctgcaaa tagctaatca cgcgcttgct gccgtccata
    14521 tccttgattt gctgtgaaaa ataaccaata cggatcgtct cgccaatctc tagctgacca
    14581 gctgttggtt ttaagtcacc agtcatcaag ctaagcaggg tggtctttcc agcaccgtta
    14641 gctccaacaa tgccgatacg gtccttattt tgaatgatca ggttaaaatg ctcaataatg
    14701 gcctgatcac cataagcaaa ggaaacctcc ttgaaattaa tgaccttctt gccaatacga
    14761 ctggcttcaa aggccatatc taattgatct ataggccttt cctgatgaag gtcctttttt
    14821 aactgttcaa agcggttaat tctggcctgc tgcttggtcg cacgcgcctg tggctgtgtc
    14881 ctcatccaag ccagctcctg tttatagagc tgctttttct tatgcaaatg agctgcttcg
    14941 cgctcgtctt gctcagcctt cagacgcaca taatcctggt aattgccctg atattcagtc
    15001 acatgagcct tatccaattc aaagatacgt gtggctatac tatccaaaaa atagcgatca
    15061 tgtgtaataa atagaacagt ccttttagag gtccttaagt aatgacttaa ccaagcgatg
    15121 gtatcaatat ccaaatgatt ggtcggctca tctagcagca acaaatcact ggctccaagc
    15181 aagacctgag ccagctgtac ccgacgtctc ataccaccgg acaggtcacc cactctctga
    15241 tccagattga caataccaag ctttgataag accgtcttaa cctcactttc gatcgaccaa
    15301 acatctaatc gatccatctc agtcatcacc tctgctagct tttcctgatt gctatctgaa
    15361 tagtcagcca tcaacagctc atattggcga atcagctgca tttcctttaa ttctagggac
    15421 agaacagtat ctaaaacaga ctgatcatca tcaaagtccg gctcctgtgt taaataagat
    15481 atacgatagt catttgcctt tgaaaaaggt gagcggtcac catcaaagcc cactttttca
    15541 gaaataacat caagcaaggt tgtttttcct gtcccattga caccaataat gccaatgcga
    15601 tcaccagcat gaataataaa ggaaatatcc tgaaaaacgg tcttatctcc aacagacttc
    15661 gtcagatgtt caacgataaa atcactcatt tagtagttcc cttctaacaa aagcctcaat
    15721 gtgttctctt tgattgacga gacgcccctc tacaatggcc tgctcaatct gatttaaaag
    15781 cattcccagc tgtggtcctg gcttcattcc aagctcacga atcagataag agccattgac
    15841 cacaatatca tgcttatcat ggatcgtcag ctcctgatac aagctctcaa cacgcttggc
    15901 ctcactgacc aagccctgtg cctgtcgtaa atcgtcaacg agtaaagcca agtccttgcc
    15961 aaacgagtaa atatcccatt tttctagctg tctttcttgg cgaatctgat aaagagaggc
    16021 catcatcgta accctacgct gaaaatcatt agaggttttc caagccttta aaaaggcttt
    16081 aggctgatca agctccagca taaccagcaa ataggcccaa gcctgatgat tgtcctgaaa
    16141 cacataatcc gctgctaagg ttttcaggta cttttgcagg gcttcttcct tgcccactaa
    16201 gcctggcaaa tagttaaagg cctgacatgc caccatagct aagatacctt tacgccattt
    16261 tggggccatt aaaagcttat caagctcaat aaaagagcgc tcaatagaaa tcttctccag
    16321 caagggagca tggcttttca ttgcttcaaa ggtctcagcc tcaatatcaa aatctaagct
    16381 ggcagcaaac cgaaagcctc gcataatccg cagggcatcc tcctcaaagc gctcctgagg
    16441 ccttccaaca gctcttagaa gcttatgctt taggtcctct aagccattaa agatatcaat
    16501 aacctgtccg tcctcatcta aggcaagagc attgacagta aaatcccttc gttttaaatc
    16561 ctcttccaag gaccgaacaa aggatacctg actagggcgc ctataatcca cataaacgtc
    16621 ctcagttcga aacgttgtga tctcatattc actgccattt tctaaaacaa gcactgtgcc
    16681 atgctcaatc ccaacatcaa ttgttcttaa gaaaatagcc tttgtctcct ctggatagca
    16741 gctagcagct atatcaacat catgaatagg cctgtttaat aagctatccc tcacacttcc
    16801 accaacaaaa taggcctcaa agccagcctg cttgattttt ttcactattg gtaaagcctt
    16861 ctgaaattca gaaggcattg tcattaatgt tatcatgttt taatctacca cctaaaagct
    16921 cctagagcct tgtcatatgc ttcccgttaa aggctgtcat atcaagctca gattggtcat
    16981 gggcaagcct ctttagacaa gaggcgttat gccaaaggca acagctcctt ctccaagatg
    17041 ggctgcaatc actgcaccaa aatgaacctc ctcaacaggg caggtatagc cattatccaa
    17101 caagagctgc tttaagatat cagccttatc ctgcgctcta gcatggataa ttgatacctc
    17161 gtactgacca ctagctgtca attcctttaa gatatcaacc aagcgcttca tggccttttt
    17221 ttccgttcta accttttcat agacgacaat ctttccttca ctatcaaagc gaagaattgg
    17281 cttgatgctg agcaaatttc ccagcaaagc agaaccgttt gataagcgtc ctcccttgac
    17341 caaatgattc aaatcatcaa ccatgataaa ggctgtggtt ccagcgattt gctcttctag
    17401 cttatccata atctctgcaa agctcaagcc ttgctgagac cactctaaag catttctaac
    17461 catgctgcct aatggtgctg aggtgatttt actatctgga aaagcaatgg tcaactcagg
    17521 gtgctcctcg atgagaaatt gaatattttg ccaaaatcct gaaataccac tagccaagaa
    17581 caagccaatc acatgagtat agtgctcagt tgacagacgc cctagtaaat catctaattc
    17641 agagaggctg ggctgactgg tttttggcag ctcttgagat tctctcatgc tttggtaaaa
    17701 ggcttcaatg gtcaggtttt gtccttcgac atagctttga ccatctatga ttacaggtat
    17761 gtctaataca aaaatatcgg catgctccgc taactgctct ggaaggtgag ctgtattatc
    17821 agttattatt gctaacttca ttaactttta aactccaaat taataccagg acgatccaag
    17881 gcaatttctg tcacttcgta ggtcaagcgc ttcaccatgt ctaataatgg agcagccaag
    17941 gattcgacct cctcttgtgt aaattcacta ggcttatcca ccaagcgtcc taaaatacga
    18001 accatctgtg aaatcacacc actaatcaca aactcttcct tgacaatgac aaattgtaaa
    18061 acagaaacaa tagccgtctc tttattttcc acatctttat taatcaactg aaaggttact
    18121 tcaaagtttg tttccggtgt tccattttct ttttcccatt ctaaatttct ggcgtcataa
    18181 tggtactgat tgacaaattc tttttcacgt actaattgca tgatttcgtt ctccttaatg
    18241 gcgatatgac ccattatagc atagatttga cgaatattaa agtagactta aaccagtatt
    18301 ttggataatt tttttccaga ccttgtcact tcaataaata taaacctgcc ttctatcaac
    18361 caatcaatct cctacaacaa aaaaacaccc caaggtgtac tgcccccaaa aagttgaacg
    18421 aataattatt gaaaggattt agttctgtat tgaacagggc taagtccttt tagtttagtt
    18481 ttgattcgtt tattgttgta gtaaaagatg tattcagtga ttgcttgttc gagctcatcc
    18541 agtgagtggt aggatttctc aaagccatag aacatctctg actttaaaat gccaaagaag
    18601 gattccatca tcccattatc agggctg
//
LOCUS       DARYXS010000035        18265 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.036, whole genome shotgun sequence.
ACCESSION   DARYXS010000035 DARYXS010000000
VERSION     DARYXS010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18265
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.036"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(85..1350)
                     /locus_tag="TV193_000992"
     CDS             complement(85..1350)
                     /locus_tag="TV193_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEL1513196.1"
                     /translation="MAEFHFDIDQIANNAITKTDKTTDIITKLPTNTTGQISFYEKLS
                     PEQQQAITAKAPALVDTFMEDQNALLDFGQAAVEGVNATVNHILAEQKKLQIPQVDEL
                     LKNTNRELNGFIAKYKEATAAELEKKPTLLQKLFKQSKNTLQEFYFDSQTIEQKMDGM
                     AAAVVKQEDTLARNIVAAELLIEDNTKSIENLVGVIAFLEASQKETSSRALTLQQELA
                     VLDTTTPEYQVQSDLLARTTEVLNTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGIMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPN
                     LERTAQSPTISLTSVTALAESLVAQNNGIIAAIDQGRKERAQLEAAIIKSAETINDSV
                     KLRDQSIIQALLNEGKEKQETIEQTERQP"
     gene            complement(1364..2221)
                     /locus_tag="TV193_000993"
     CDS             complement(1364..2221)
                     /locus_tag="TV193_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513197.1"
                     /translation="MSRKYYQVSRRRKGFSWFGWLIGFAILVGVVENIDKAVLIFAAL
                     GVGYAAYRYSNRQARLKTATLEKRLEDLKATIQLADRKVKLLDHYLAKEDFTQYAILA
                     KQLLPQLSEIKKESGHLKEHMDISIYRRVTKKANDVESDVQLQLEKIQIAANLKAESL
                     KEQAADPIYKAPELRHYYDNIQADHHSILEKIKGADNHEELLALHEANMRRFQDILQG
                     YLKIKETPKNYYNADERLQQALEAIQQFDLDLDETLRKLNESELKDFDVSLRMMKGSA
                     QASEANTTN"
     gene            2564..3856
                     /locus_tag="TV193_000994"
     CDS             2564..3856
                     /locus_tag="TV193_000994"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEL1513198.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIV
                     IDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRA
                     HVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERL
                     KTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPEN
                     ARNYVRRIGELVGVRISTFSVGPGREQTNILESVWATI"
     gene            complement(3971..4744)
                     /locus_tag="TV193_000995"
     CDS             complement(3971..4744)
                     /locus_tag="TV193_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEL1513199.1"
                     /translation="MTTKGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQK
                     TLPEKMLSTDGLKTEIVGQEKTVEEIIAEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAEGLHTAIETTAFAKHEQFAELINYVDFIYTDLKHYNRLKHTKVTGVRND
                     LIIKNIHYAFEMGKEVVLRIPVIPNFNDSLEDAKAFSELFNQLNINQVQLLPFHQFGE
                     NKYKLLGRSYDMADAVAYHPEDLVDYQQIFLNHHIHCYF"
     gene            4869..5615
                     /locus_tag="TV193_000996"
     CDS             4869..5615
                     /locus_tag="TV193_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1513200.1"
                     /translation="MNRLEKIIQLVFQKKKIDVNTLSEQLQVSKVTIRKDLDKLESKG
                     LLRRVHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKQNIKIITNSCFIASYIRQYSSCQLILLGGYYQPNSEVTVGPLLKEMISLFHV
                     DRVFVGTDGFDPAIGFMGKDMMRSEGVRYMAEASEELIILTDSSKLSKPSLVHQLSLE
                     AVDRMITDEQLEASTYKLLQEHGIAIDFIS"
     gene            5630..6610
                     /locus_tag="TV193_000997"
     CDS             5630..6610
                     /locus_tag="TV193_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEL1513201.1"
                     /translation="MKEGRKRLLAKVAYLHYVQGKSQTAISKQMNIYRTTVCRMLAKA
                     RAEGIVRIEIADYDANLFALEEYVRQKYGLEKLDIVSNQMEDSPSDTLVKVAKTAAEV
                     LRSTVKDGDKIGLSWGATLSSLIDELDPKVMKDIMVCPLAGGPSHINAKFHVNTLVYR
                     LARIFHGNSSFINAMVVQKDKQLTRGILQSKYFEETLTYWNHLDLALVGIGGEPNGHQ
                     TSQWRDLLTDKDYKQLADDKAVGEVCCRFFDQEGHSVHQELQDRTIGISLEQLARVPK
                     TIAVAVGQAKAKAILAALKAKFINYLITDKATIMAVLALDQDQTADTYLS"
     gene            6849..7169
                     /locus_tag="TV193_000998"
     CDS             6849..7169
                     /locus_tag="TV193_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1513202.1"
                     /translation="MELIVPDQIIMGLILNAGDAKQHIYQALKLAKAKDYEASDKELA
                     LADDALLEAHNLQTQFLAQEASGAKADITALFVHSQDHLMTTITEINFIKEIIELRKE
                     LAEN"
     gene            7194..7502
                     /locus_tag="TV193_000999"
     CDS             7194..7502
                     /locus_tag="TV193_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1513203.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIACEIEAYSQGKLAD
                     YAPAIDVALLGPQVAYTLDKSEVICKENGIPIAVIPMADYGMLDGDKVLDLALSLIKE
                     "
     gene            7513..8817
                     /locus_tag="TV193_001000"
     CDS             7513..8817
                     /locus_tag="TV193_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1513204.1"
                     /translation="MANMNAQKIIAPIMRFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVLGADWTEPFMQVYQGTFAIMGLISCFSIGYSYAKNSGVEPLP
                     AGVLSLSAFFILLRSSYVPKKGEAIGDAISKAWFGGQGIIGAIIIGLVVGAIYTAFIR
                     RHIVIKMPEQVPWAIAKQFEAMIPAFAIFILSMLVYIIAKLVTGGGTFIEMIYAVIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALLAAGDLS
                     LAKGAHIVTQQFLDSFLILSGSGITFGLVIAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVVAALIVYGSIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGALVQALILVLSTVIYFPFFKVQDNIAYQNELAAEKA"
     gene            9098..11515
                     /locus_tag="TV193_001001"
     CDS             9098..11515
                     /locus_tag="TV193_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEL1513205.1"
                     /translation="MTEAKNPYFGTLTERMHRYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPSNLKRAYMLQNILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRELAPFWENNNLRARCGVLLPKEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEVGLKGFEERTRAAKAALDLTIPESIDKYHFYDSVLIVIAAV
                     KAYAERYAKLARELAKTANPERQAELLEIARICDKVPYQPAETFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYAKADLEAGRETEDSIVERLINLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKQDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNR
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFATGHGHFKDMTSYDELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTTDELWHALETDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKMKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKNPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            11530..12198
                     /locus_tag="TV193_001002"
     CDS             11530..12198
                     /locus_tag="TV193_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1513206.1"
                     /translation="MEYMLDTLNLEAIKKWNRILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVVAQDYEGILKDAAAIRQQCGDSIYVKVPVTTEGLTAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKILAASFKNVAQVNRAFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWQAIHH
                     RQTI"
     gene            12323..13414
                     /locus_tag="TV193_001003"
     CDS             12323..13414
                     /locus_tag="TV193_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEL1513207.1"
                     /translation="MKVFASPSRYIQGKNALFTNSDIIKKLGQKPVLLCDDIVYGIVG
                     ERFEGYLSEHGLPPVHVAFNGEASDNEINRVVAIARENDNDVIIGLGGGKTIDSAKAI
                     ADILEIPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYAKNPELVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGLAIAEACERTLFADGLKAMA
                     SCEKKVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLTQLFLENKSREEIDRYVDFYQAIGMPTTLKEMHLDTATEEDFLKIGRQATMAGE
                     TIHQMPFTITAEDVASALVAVDAYVCSRT"
     gene            13921..14973
                     /locus_tag="TV193_001004"
     CDS             13921..14973
                     /locus_tag="TV193_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEL1513208.1"
                     /translation="MIRKIGIVSLSSGMLGEANVKHELDLGLARLKQLGLEVTILPNA
                     LKGIDYFDQHPEARAADMIQAFADPSIDMILCAIGGVDTYRLLPYLFIEHQLQDVVNQ
                     KVFLGFSDTTINHLMLHKLGIKTFYGQSFLADICELADDMLPYSLAYFKELLETGTIA
                     EIRPSEKWYEERTDFSANSLGTQRIAHRNQGFELLKGPSLFKGEILGGCLESLYKLLD
                     SSKCSDSAKLCEQYQLFPDLSDWAGRLLLLETSEDKSDPAQYRRMLETLKATGIFSVI
                     SGLLVGKPIDNSYYDDYKQQLLAVVDNDIPILYNVNVGHATPRAIVPFGVMAVVDAKE
                     QVIRFVPDEHTDQNDV"
     gene            15002..15580
                     /locus_tag="TV193_001005"
     CDS             15002..15580
                     /locus_tag="TV193_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1513209.1"
                     /translation="MPKVDTITQVYFIRHAEPNYQNHNDVTRELSEHGVKASQDLVRQ
                     LAEVSIDAFYSSPYKRSIDTIAPLAASRAMEIKLIDDLRERKLADAWIEDFVDTAKKQ
                     WDDFTFKLPTGESLQEVQDRNIAALNRILKEAKGKTVVIGTHGTALSTLINYYQPDFG
                     FEDFDRYKHVFPWIVRASFDGDKLLGLNEFLV"
     gene            15776..16684
                     /locus_tag="TV193_001006"
     CDS             15776..16684
                     /locus_tag="TV193_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1513210.1"
                     /translation="MTNKTKRTGLVRKYGACSAAIALAALASLGAGKAVKADQPAALK
                     YPEPRDYFLHTREGDVIYDEDIKRYFEDLEAYLTARLGGIDKKVEEAAQKPGIPGPTG
                     PQGPKGDKGDPGAPGERGPAGPKGDTGEAGPRGEQGPAGQAGERGPKGDPGAPGPKGE
                     KGDTGAVGPKGEKGDTGATGPKGDKGERGEKGEQGQRGEKGEQGQRGEKGEQKPKGDQ
                     GKDTKPSAPKAPEKAPAPKAPKASEQSSNPKAPAPKSAPSKSAAPTGQKAALPATGEI
                     NHPFFTLAALSVIASVGVLTLKGKKD"
     gene            complement(16920..17024)
                     /locus_tag="TV193_001007"
                     /pseudo
     CDS             complement(16920..17024)
                     /locus_tag="TV193_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT         5054 a         3752 c         4203 g         5256 t
ORIGIN      
        1 tgacagaagg gtatttttga ttgttaccaa tcaaaaagcc acaggctggg tagctgtggc
       61 aggtctgtta tatcaggagc tgctttaagg ctggcgttct gtctgctcga ttgtctcctg
      121 cttttctttg ccctcattga ggagagcttg aatgatgctt tggtcgcgca gcttgacaga
      181 atcattaatg gtttctgctg atttgataat ggctgcttcc agctgagctc gctccttgcg
      241 tccttgatca atggcagcaa tgatgccgtt gttctgggca actagacttt ctgctagtgc
      301 tgtcactgag gtcaacgaaa tcgttgggct ttgagctgtc cgctcaaggt ttggaatcgc
      361 ttccttgctt gtctcagcta gcatttgtag ggcagcgttg ttggcattga caatggcgtc
      421 tgcggtcatt ccagacttga cagactgctg catgatacct agctgagcaa tagataattt
      481 catggttgga atggtattgc gtcgcagcat gcctagcttt tgtcgcatgt cagaggacac
      541 cttgacgagg ttacgcattt gcggtgttgt tgcccaagcc acatagagtc gactaaggta
      601 ttcggtgtgc tgctgctcaa gggtattgag cacctctgtt gtcctagcca ataggtcaga
      661 ttgcacctga tactctggtg ttgtcgtgtc aagtactgca agctcctgct gcaaggtaag
      721 ggcgcggcta gaggtttcct tttgactagc ttcaagaaag gcaatcacac caaccagatt
      781 ttcaatcgac ttggtattgt cctcaatcaa gagctctgcg gctacaatat tacgagcaag
      841 cgtgtcttct tgcttgacaa cagctgcagc cataccgtcc attttttgct caatggtctg
      901 agaatcaaag taaaattcct gaagcgtgtt cttgctttgt ttgaatagct tttgcaaaag
      961 cgttggcttt ttttcaagct cagcagcggt cgcttcctta tatttggcaa taaaaccatt
     1021 aagctcacga ttggtgtttt tgaggagctc gtcaacctgt ggaatttgta atttcttttg
     1081 ctcagctaga atatgattaa cagtagcatt aactccttca acggctgctt gaccaaaatc
     1141 aagtaaggca ttttggtcct ccataaaggt atcaacaagt gctggtgcct ttgcagtgat
     1201 agcctgctgc tgctcaggac tcagcttttc gtagaaagaa atttgtccag tagtattggt
     1261 tggtagctta gtgataatat cggtggtttt atctgtttta gtgatagcat tattagcgat
     1321 ctggtcaata tcaaagtgaa attctgccat aatagctcct ttatcagttg gtagtgttag
     1381 cctcgctagc ttgagcagag cccttcatca tgcgcagact aacatcaaaa tcctttagct
     1441 cactttcgtt aagcttcctt agggtctcat caaggtccag gtcaaattgt tggatagcct
     1501 caagagcctg ctgcaagcgc tcatcagcat tgtaataatt tttaggtgtt tctttgattt
     1561 ttaggtagcc ctgcaaaatg tcttgaaacc tgcgcatatt agcctcatgg agtgctaaga
     1621 gttcctcgtg attatcagct cccttgattt tttctaaaat cgagtggtgg tcagcctgga
     1681 tattgtcata atagtgacgt agctcgggcg ccttataaat ggggtcagct gcctgctcct
     1741 ttaggctttc agccttcaga tttgctgcga tttgaatctt ttcgagctgt agctgcacat
     1801 cgctttccac gtcattagcc tttttggtca cacgacggta aatgctaata tccatgtgtt
     1861 ccttgaggtg accgctttct tttttgattt cactcaattg cggcagtagc tgcttggcta
     1921 aaatggcata ctgtgtaaaa tcttccttag ccagataatg atcaaggagc ttaacctttc
     1981 ggtcggcaag ctgaatagtt gcctttaaat cctccaagcg tttctcaagt gttgccgttt
     2041 ttaagcgagc ctgacggttc gaatagcgat aagcagcata accaacaccc agcgctgcaa
     2101 aaatcagaac agctttgtca atattttcta caactcctac taaaatcgcg aagcctatca
     2161 gccagccaaa ccagctaaag ccctttcttc gtcgagatac ttggtaatat tttcgtgaca
     2221 tgtaaaactt cctttgtact ttttatcaca gtaaacaatc aattagttct attttacctt
     2281 aaaaatgtga tttcttaaag gaaagattag cagatttagc attattttcc ttcaaagact
     2341 ggtcttgctt gctttttagt gaaatgtttg ctttctgcct gttttcagaa aaaagcattt
     2401 gccatttgat attttttctt aataatacca aggaaagata gcagaaaacc acattttttg
     2461 ctataatgag gtgtaacaga cacttgcagg tgagagtcct gccacattta tcaagaaagg
     2521 tgggggctct ctttctttgt tgagatgagc ctatatcgaa gatatgacat cagtagtagt
     2581 agttggtacc cagtggggtg acgaaggtaa gggtaagatc actgactttt tatcctcaga
     2641 tgcagaagtg attgcacgtt accaaggtgg tgacaatgca ggacatacca ttgttattga
     2701 taacaagaaa ttcaagctgc acctgattcc atcaggtatt ttcttcccag aaaagatttc
     2761 tgtgattgga aatggtgtgg ttgtcaatcc aaaatccttg gttaaggagc ttgcttacct
     2821 gcatgaggag ggcgtgacca cagacaattt gcgcatttct gatcgtgctc atgtcatttt
     2881 gccataccat atcaagcttg accagcttca agaggaagca aagggtgaca ataaaatcgg
     2941 taccaccatc aagggcatcg gtccagccta tatggataag gcagcacgtg ttggtatccg
     3001 tattgcagac ctgttagaca gggatatttt tgctgagcgc ttaaagacga atctggctga
     3061 gaaaaatcgt ctttttgaga aaatgtatga cagcgcaccg attgcatttg acgagatttt
     3121 tgaagaatac tatgcttatg gtcaagagat caaaaaatat gtgacagaca catctgttat
     3181 tttgaacgac gctcttgatg cgggcaagcg tgtccttttt gagggagctc aaggggttat
     3241 gcttgatatt gatcagggaa cctatccatt tgtcacctca tctaatccag ttgcaggcgg
     3301 tgtgaccatt ggttcaggag tcggaccaag caaaatcaac aaggttgttg gagtatgtaa
     3361 ggcctatact agtcgcgttg gtgatggacc attccctacc gagttatttg acgaggttgg
     3421 tgagcgcatt cgtgagattg gtcatgagta tggaacaacc actggtcgtc cacgtcgcgt
     3481 tggctggttt gattctgttg tgatgcgtca tagccgtcgt gtgtcaggca ttaccaatct
     3541 atcacttaac tctattgatg tgctatcagg ccttgagact gtaaaaatct gtgtcgctta
     3601 tgaccttgat ggtaagcgca ttgatcatta cccagcaagc cttgagcagc taaaacgctg
     3661 caaaccgatt tatgaagagc ttccaggctg gtcagaggat attaccggtg ttcgcagcct
     3721 tgaggatctc ccagaaaatg ctcgcaacta tgttcgtcgt attggcgaac tggttggtgt
     3781 tcgtatctca accttctcag taggtccagg acgtgagcaa accaatatcc ttgaatctgt
     3841 ttgggcaact atctaagctg tctattgtga tagcaccagc cttagctgaa tattaacgaa
     3901 aacacgagca atcctaagga aggttatccg gaggagctgc tcatgttttt taggtatagg
     3961 gcttttaaga ttaaaaatag caatggatat gatgattgag aaagatttgc tgataatcca
     4021 ccagatcctc tgggtgataa gcgacagcat cagccatgtc atagcttctg cctagcaatt
     4081 tgtatttgtt ttcaccaaac tggtgaaagg gaagtagctg cacctgatta atgtttagct
     4141 gattgaaaag ctcagaaaat gccttggcgt cctccaaaga atcgttgaaa ttcggaatga
     4201 cagggatacg caagacgact tccttgccca tctcaaaggc gtagtggata tttttaatga
     4261 tcaggtcatt tcgcaccccg gtgaccttgg tgtgctttag gcgattatag tgcttcaaat
     4321 cggtataaat aaagtctaca tagttgatca gctcagcaaa ttgctcgtgc ttagcaaagg
     4381 ctgtcgtttc gatagctgtg tgtagccctt ctgccttagc agcctttaga agcgctaagg
     4441 caaagtcaaa ttgagcaaag atttcaccgc cagacaaggt cataccaccg ccagattcct
     4501 cgtaaaaatc aagatccttt aaaacctcag caataatctc ttcaaccgtc ttttcctgac
     4561 caacgatttc tgtctttagt ccatctgtgc ttagcatttt ttcgggtaac gttttttgtg
     4621 attcgggatt ggcacaccag ggacagcgta agggacaccc cttgagaaat acagttgtgc
     4681 gaatgcctgg tccatcgtgt atgctaaaat gctggatatt aaatacaatg ccttttgtcg
     4741 tcatagcgag acttcctttc gttctaggac tatcataaca gataaacgta aataaatcaa
     4801 ttacgaacga aagttatttt tgcttttcat ttaccgccat aattgttaca atggaaagga
     4861 ggtaaattat gaatcgttta gaaaaaatta tccaattagt atttcaaaag aaaaaaatag
     4921 atgttaatac tttatctgag cagctacagg tctccaaggt aaccattcgt aaggatttag
     4981 acaagcttga aagtaagggg ctgctgcgtc gtgtgcatgg ctatgcggtg ctcaatagtg
     5041 gtgatgattt gaatgtgcgc ctgtcctata attataacat caaaaggcgg attgctgaaa
     5101 aggctgccga gctggtgcag gacaacgata ctatcatgat tgagtcagga tcgacctgtg
     5161 ccctgttggc agaggtgctc tgtcaaacca aacaaaacat caaaatcatc accaactcct
     5221 gctttattgc aagctacatt cgtcagtata gtagctgtca gcttatcctg ctggggggct
     5281 actatcagcc taattctgag gtgaccgtag gcccactttt aaaggaaatg atttcgcttt
     5341 ttcatgtgga tcgtgttttt gttgggacag atggctttga tccggcaatt ggctttatgg
     5401 ggaaggatat gatgcgctca gagggcgtcc gttacatggc agaggcttct gaggagctta
     5461 ttatcctgac agattctagc aagcttagca aacccagtct ggttcatcag ctatcgcttg
     5521 aggctgttga ccgtatgatc acagatgagc aattggaggc aagcacctat aagctcctgc
     5581 aagagcatgg tattgccatt gactttatat cgtagcgtag ggaactcaaa tgaaagaagg
     5641 acgtaaacgc ctgcttgcca aggttgccta cctgcattat gtgcagggca aaagccaaac
     5701 cgctatttca aagcaaatga atatttaccg aacaacggtc tgtcgcatgc ttgccaaggc
     5761 tagggctgaa ggcattgtgc gtatcgagat agctgattat gatgctaatt tgtttgcctt
     5821 ggaggagtat gttcgtcaaa aatatggctt agaaaagctt gatattgtat ccaatcaaat
     5881 ggaagatagc cctagtgata ccttggtaaa ggtggccaaa acagcagccg aggttttgcg
     5941 cagtacggtc aaggatggtg ataagattgg cttatcgtgg ggggcaacgc tgtcaagtct
     6001 gattgacgag ctggatccta aagtaatgaa ggatattatg gtgtgtccct tggctggtgg
     6061 tcctagtcat atcaatgcca agtttcatgt gaatactctg gtttatcgct tagcaaggat
     6121 ctttcatggc aatagctcct ttatcaatgc tatggtggtt cagaaggaca agcagctaac
     6181 cagagggatt ttgcagtcca agtattttga agaaaccctg acctattgga accatcttga
     6241 ccttgctctg gtcggtattg gaggagagcc aaatggtcat cagaccagtc agtggcgtga
     6301 tttgttgact gataaggact ataagcagct ggcagatgac aaagctgttg gtgaggtctg
     6361 ctgtcgcttt tttgatcagg aggggcatag tgttcatcag gaattgcaag acagaacgat
     6421 aggcatttca ctggaacagc tcgcgcgtgt gcctaagaca atagctgttg ctgttggtca
     6481 agctaaggcc aaggctattt tagcggcttt aaaggctaaa tttatcaatt acctcatcac
     6541 cgataaggct actatcatgg ctgtcttggc tttggatcag gatcagacag ctgacaccta
     6601 tctctcatag caatagctta atcagaagac gattgttttc tgattttttt gtgaccaaaa
     6661 atcttgcaaa gcatcacttt tgcacaatag tgctaaaaaa taaatacagc acacaatata
     6721 ttgacgaagg aagtaaaaat gataaaatga acttatcaaa gaaatgtaaa cgattacaaa
     6781 cgcaagctgt ttttttacga aaaaagcaag ggtaatcctt acatgagcac gtcacaaagg
     6841 agaaacaaat ggaattaatt gtaccagacc aaatcatcat ggggttaatc ctaaatgcag
     6901 gagatgcaaa gcagcatatc tatcaagccc taaagctggc taaggctaaa gactatgagg
     6961 ctagtgacaa ggagttagcc ttagctgatg atgctttatt agaggcgcat aatttgcaga
     7021 cacaattttt agctcaggag gctagcgggg caaaggcaga cattacagcc ttgtttgtcc
     7081 attctcagga tcacttgatg acaactatta cagaaatcaa ttttatcaaa gaaatcattg
     7141 agcttcgtaa ggaattagca gaaaactaaa gatcatatca aaaggaggac gttatgatta
     7201 aaattggctt attttgtgca gcaggctttt caacaggcat gcttgtgaac aacatgaagg
     7261 tggctgctga gaaaaagggc attgcttgtg agattgaagc ctactcacaa ggaaagctgg
     7321 cagactatgc accagctatt gatgttgccc tcttaggtcc acaggtggct tataccttgg
     7381 ataagtcaga ggttatctgt aaggaaaacg gcattccaat agctgttatc ccaatggctg
     7441 attatggtat gctagatggt gataaggtgc ttgacttagc gctcagcttg ataaaggaat
     7501 aggagcttgg tcatggctaa tatgaatgct caaaaaatca ttgcaccgat tatgcggttt
     7561 gttaatatgc gtggcattat cgctctaaag gacggtatgc tggcgatttt acccttgacg
     7621 gttgtcggaa gtctttttct tattgcaggt cagattccct ttcagggggt caatgacgct
     7681 atagcgagtg tccttggggc agactggaca gagccattta tgcaggttta tcagggtacc
     7741 tttgctatta tgggcttgat ttcctgcttt tcgattggct attcctacgc taaaaattcg
     7801 ggtgtggagc cactgccagc aggtgtgcta tcattgtcag ccttctttat cctgctaagg
     7861 tcctcttatg tgccaaaaaa gggtgaggct attggtgatg ccattagtaa ggcttggttt
     7921 ggtggtcaag ggattattgg tgccatcatt attggcttgg tggttggtgc gatttataca
     7981 gcctttattc gtcgtcatat cgtcatcaaa atgccagagc aggtgccgtg ggccattgcc
     8041 aagcaatttg aagcgatgat tccagccttt gcaatcttta tcctgtcaat gcttgtttat
     8101 atcattgcaa agctagtgac aggtggcggc acctttattg aaatgattta cgctgtgatt
     8161 caggtgcctc tacagggctt gactggctct ctttacggtg cgattggtat tgcctttttc
     8221 atctccttcc tatggtggtt tggtgtgcat gggcaatcag tggtcaatgg tatcgtgaca
     8281 gcgctgctct tgtcaaatct agatgctaac aaggccttgt tagcagcagg tgatttgtct
     8341 ttggctaagg gtgctcatat tgtgacgcag caatttttag attctttctt aattttatca
     8401 ggctcaggta ttacctttgg cttagtgatt gccatgattt ttgcagccaa atcaaagcag
     8461 tacaaggctc taggcaaggt agcagccttt ccggctctct ttaatgttaa tgaaccggta
     8521 gtctttggct ttccaattgt gatgaaccca gtgatgtttc tgccatttat tttggtgcca
     8581 gttgttgcgg ctctgattgt ttatggctct attgcgattg ggtttatgca gccatttgca
     8641 ggtgtaacac ttccttggtc tacaccggct attatctcag gctttatggt tggtggctgg
     8701 cagggggctc ttgttcaggc tttgattctt gtcttgtcaa ccgttattta cttcccattc
     8761 tttaaggttc aggataatat tgcttatcaa aatgaattgg cagctgaaaa agcttaacag
     8821 tatgctgata tcaatcacca tgacttaaaa acagtcttta gtcactagct atagcattcc
     8881 tagagaaggg cttagagaag gaggatttct tcacgtaacc atctcaatga ggtggttttt
     8941 ttgaaagaga ctcttagaca agtctatttt tgcacgatag tgcaacttta aatgaatagc
     9001 tgaatgctat ggatatgata ggcaaaatgt tttaaatatg gtaaaataat tacgaaagaa
     9061 agtaatttaa tttcgtaaga aacaaaggag gcctaatatg actgaagcaa agaatcccta
     9121 ttttggtaca ttaacagaaa gaatgcaccg ctatcgtgag gcagttctag ataaaaagcc
     9181 ttatattgat gctgagcgtg ctattttagc aacagaggct taccaaaaac accaaaacaa
     9241 gccatctaat ctaaaacgcg cttacatgct gcaaaatatt ttggaaaaca tgaccatcta
     9301 cattgaggac gaaagcttga ttgctggtaa tcaggcgtct tctaacaagg atgcacctat
     9361 ctttccagag tacactcttg aatttgtcct aaatgagctt gacctttttg aaaagcgtga
     9421 tggcgatgtg ttttacatca ctgaagaaac caagcagcag cttcgcgagc ttgcaccctt
     9481 ctgggaaaat aacaatttgc gggcccgctg tggtgtcttg ctgccgaaag aggttcaggt
     9541 ttatatggaa actggcttct ttggcatgga aggcaagatg aattcaggag atgcccattt
     9601 agctgtcaat taccaaaagc tattagaggt tggcttgaag ggctttgagg aacggactcg
     9661 tgctgccaag gctgcgcttg atttgactat tcctgaaagc attgataagt accattttta
     9721 tgattctgtt ctgattgtga ttgctgcggt taaggcttat gcagagcgct atgccaaatt
     9781 ggcgcgtgag ctggccaaaa cagctaatcc agagcgtcag gcagaattgc ttgaaatcgc
     9841 gcgtatctgt gacaaggtgc cttaccagcc ggcggaaacc tttgctgaag cggtccaatc
     9901 agtttggttt atccagtgta ttcttcagat tgagtcaaat gggcattctc tttcttatgg
     9961 ccgatttgat caatacatgt atccatatgc caaggctgat ttggaggctg gtcgtgaaac
    10021 agaggattct atcgttgagc gcttgattaa cctttggata aagactctga ccatcaataa
    10081 ggtacgcagt caggctcata ccttctcatc agcaggtagt ccgctgtatc aaaatgtcac
    10141 cattggtggg caaaccagag ataagcagga cgctgtaaat cctctatcct acctagtgct
    10201 tcgcagtgtg gctcaaacca aattaccaca accaaaccta accgttcgat atcacaaggg
    10261 cttggataat cgttttatga atgaatgcat tgaggttatg aagcttggct ttggtatgcc
    10321 agctatgaac aacgatgaaa tcatcattcc gtcctttatc aaaaagggtg tccttgaaga
    10381 agacgcctat gattattcag caattggctg cgttgagaca gccgttccag gtaaatgggg
    10441 ctatcgctgt actggtatga gctacattaa ctttccgaag attttgctta tcaccatgaa
    10501 tgatggtatt gacccagctt cgggtaagcg ctttgcaaca ggacatggtc acttcaagga
    10561 tatgacctct tatgacgagc taaaggcagc ttgggacgcg actctgcgtg aaatcactcg
    10621 catgagtgtc atcgtagaaa atgccattga ccttgggctt gaacgagagg tgccagacat
    10681 tctttgctct gcattgaccg atgattgtat cggccgaggc aagacgctca aagaaggtgg
    10741 agcagtctat gactacatct caggcttgca ggtggggatt gctaacctgt ctgattccct
    10801 agctgcactg aaaaaattgg tgtttgagga gggtcgccta accactgatg agctctggca
    10861 tgctctagaa acagactttg caggtgagcg tggtgaagag atccgtcaaa tgctgattaa
    10921 cgatgcacca aaatatggta atgatgatga ctatgctgat agcttagtgg ttgaagccta
    10981 tgatacctac attgatgaaa ttgctaaata ccctaatacg cgctacggac gtggtccgat
    11041 tggtggtatt cgctactcag gcacctcatc tatttcagct aatgtcggcc aaggtaaggg
    11101 aaccttagct accccagatg ggcgtcatgc aggaacaccg cttgctgagg gctgctcacc
    11161 agagcacagt atggataaaa aaggaccaac ttctgttttg aaatccgttg ccaaattgcc
    11221 aacagatgaa attgtaggtg gggtcttact caaccaaaag gttaatcctc agacactagc
    11281 aaaagaagaa gacaagatga agctgatggc tctgcttcgg accttcttta acaggctaca
    11341 tggctatcat attcaataca acgtcgtctc acgtgaaacg cttattgatg ctcaaaagaa
    11401 tcctgaaaag caccgcgact tgattgtgcg tgtggcaggc tattcagcct tctttaatgt
    11461 tttatcaaaa gccactcagg acgatatcat cgaacgtacc gaacacacac tataggagaa
    11521 caattactta tggaatacat gctagatact ctaaatctag aggctattaa aaagtggaat
    11581 cgcattttac cccttgcagg ggtaacctca aatccttcaa ttgctaaaaa agagggagat
    11641 attgattttt ttgaacgcat tagagaggtt cgtgcgatca ttggagataa ggcctctatt
    11701 catgtgcaag tcgtggcaca ggattatgaa ggtattttaa aggacgctgc ggctattcgt
    11761 cagcaatgtg gtgatagtat ttatgtaaag gttcctgtga caacagaggg actcacagcg
    11821 atcaaaaccc taaaggcaga gggctaccat atcacagcta cagccatcta tactaccttc
    11881 caaggcttac tggccatcga agcaggagca gattatctgg caccttacta caatcgcatg
    11941 gaaaacctca atattgatcc ggaggctgtg attggccagc tggcagaggc cattgatcgt
    12001 gaatgctctg atagtaaaat cttggcagcg agcttcaaaa atgtagctca ggtcaaccga
    12061 gcctttgctt tgggtgctca ggccatcact gctggtccag atgtctttga ggcaggcttt
    12121 gcgatgccat ctatccaaaa ggctgtagat gattttggca aggattggca agccattcat
    12181 catcgtcaaa ctatttaaaa gccatctaac ccatcgttat atgagcaaga gcagggacgc
    12241 ttctatcagc atagctagac tagtcttgct cactcttaga tggtgagaag cgtcaaaaat
    12301 ctgatttaga aagaggaaca tcatgaaagt atttgcaagt ccatcacgct atattcaagg
    12361 gaaaaatgcc ttatttacca atagtgacat catcaaaaag ctagggcaaa agccggtatt
    12421 gctctgtgat gatattgttt acggcattgt cggagaacgt tttgagggct atttaagtga
    12481 gcatggtcta ccacctgttc acgtagcctt taatggcgaa gcgtctgata atgagattaa
    12541 tcgtgtcgtt gccattgcta gagaaaatga taatgatgtc attatcggac ttggcggagg
    12601 caagaccatt gacagtgcca aggcaatcgc tgacatcttg gagataccag tgattatcgc
    12661 tccaaccatt gcctccactg atgctccaac atcagcccta tcagtgattt acacagatga
    12721 gggcgccttt gaaaaataca ttttctatgc taaaaatcct gagcttgtct tggttgatac
    12781 tcaggttatc tgtcaagcac caaagcgctt gctggcttca ggtattgctg atggtctagc
    12841 cacttgggta gaagcgcgtg cggttatgca aaaaaatggt gacacgatgg caggcggcaa
    12901 ccaaaccttg gcaggacttg ctattgctga ggcctgcgag cgtaccctgt ttgctgacgg
    12961 tctcaaggca atggctagct gtgagaaaaa ggtcgttact ccagctttag aaaatgtgat
    13021 tgaggctaat accttattaa gtggtcttgg ctttgaaagt gcaggacttg ctgctgctca
    13081 tgctattcac aatggcttta cagctttgac aggtgacatt catcacctca ctcatggtga
    13141 aaaggtggcc tatggcaccc taacacagct tttcctcgaa aataaatcaa gagaagaaat
    13201 tgaccgctac gttgactttt atcaggctat cggaatgccg acaaccctaa aagaaatgca
    13261 tttagacacc gccaccgaag aggatttctt aaaaataggg cgtcaagcaa ccatggcagg
    13321 agaaaccatt caccaaatgc catttaccat cacagcagag gacgttgcct cagcgcttgt
    13381 tgctgtagat gcttacgttt gcagcagaac ttaatgcaga actgctaaag ttctcttagc
    13441 cttatcagga gcctattgct ggtagctctt gaccaaagga ttgtacctac cttagcctta
    13501 attcaactgt tagaggtgtt cctcttgctg tggtaagaga ggttctttac tgctaaaggc
    13561 tcattctcag ggcaagctgg cccctccaaa tcatttaaaa agtcgtaaat ctaatcaata
    13621 atggctatca gtataggcta ctggtagtca ttattctata tctgatttat gagaacatac
    13681 cagtcagcag ctttgctgtg ccacctattt cttgtcatta cagtagctta gctttatagc
    13741 tgacagagca aatgcttcct catctattag ctcttaattc aaccgctaca gtaatagaaa
    13801 aagctaatca aagtaagggc tagttttttt tggtatcgct attaacagta tgtattagag
    13861 gctatcagcc tagccattat tgtggtataa tgacacaaca actttttaag gaggttagct
    13921 atgattcgga agattggtat tgtcagcttg tctagtggta tgcttggcga ggctaatgtc
    13981 aagcacgaat tggatttagg cttagcccgt ttaaaacagc taggcttaga ggtaacgata
    14041 ctcccaaatg ctttaaaggg catagactat tttgatcagc accctgaagc aagggcagca
    14101 gatatgattc aggcctttgc agatccgtct attgacatga ttttgtgtgc cattggtggg
    14161 gtggatacct atcgcctctt gccctatctg tttatcgaac atcagctaca agatgttgtc
    14221 aatcaaaagg tctttcttgg attttctgac accacgatca accacttgat gcttcataag
    14281 cttggtatta aaacctttta tggtcagtcc tttcttgccg atatttgtga gctggctgat
    14341 gacatgctgc cttactcgct ggcttatttt aaagagcttc ttgagacagg aactatcgct
    14401 gagatcagac ctagtgagaa gtggtatgag gagcggactg actttagtgc aaacagcctt
    14461 gggacacaga gaatagctca tcgcaatcaa ggctttgaac tattaaaagg tccgtcctta
    14521 ttcaagggag agatactagg tgggtgttta gagtcacttt ataaactatt ggattcgtca
    14581 aagtgttcag atagcgctaa gctctgtgag caataccagc tctttccaga tctgtctgac
    14641 tgggcaggca ggctcttgct tctagaaacc agtgaagaca agtcagatcc agctcaatac
    14701 cgccgaatgc ttgaaaccct caaagcaaca gggatttttt cggtgatctc tggattattg
    14761 gttggaaagc cgatagacaa cagctactat gacgactata agcagcagct gctagctgtt
    14821 gttgataatg atatccccat tctttacaat gtcaatgttg gccatgctac cccaagagcc
    14881 attgttccct ttggtgtcat ggctgtggtt gatgccaaag agcaggtcat tcgatttgtc
    14941 cctgatgagc atacagacca aaatgacgtc taacaaatca aaacagaaag tgagagagtc
    15001 tatgccaaag gttgacacga taacgcaggt ttattttatc cgccacgcag agcctaacta
    15061 tcaaaaccac aacgacgtga ctagagagct ctccgagcat ggggttaagg cgagccaaga
    15121 cctggttagg caactagcag aggtgtcgat tgacgccttt tattccagtc cctataaacg
    15181 ctctattgac accattgccc cactagcagc tagtagggca atggaaatta agctgattga
    15241 cgatttgaga gagcgtaagc tagctgatgc ttggatagaa gactttgtcg acacagccaa
    15301 aaagcagtgg gacgatttta cctttaaatt gccgacaggc gaaagcctgc aagaggtaca
    15361 agacagaaat atagcagctc ttaaccgtat tttaaaagaa gcaaaaggca agacagtagt
    15421 cattggcaca catggcacag cactgtcaac ccttatcaac tactatcaac cagactttgg
    15481 ttttgaggat ttcgaccgat ataagcatgt ctttccttgg atagtcagag ctagctttga
    15541 tggtgacaag ctgcttgggc ttaatgagtt tctagtctga caagtctagc cttgatccag
    15601 ctattatagg tgatgacagc aacaaaatca gataattaac cctttcatta aaaaaaaaaa
    15661 caaaacctcg gagacaaact agccagcagc tatttctcat gagtaatcaa catgttaaaa
    15721 tcttctttgg agatattaga caaccataat tattatatca tcaaaggaga gaaagatgac
    15781 aaacaaaaca aagcgtacag gattggtacg caagtacggt gcctgctcag cagctatcgc
    15841 cttagcagct cttgcaagcc tgggagcagg taaagcagta aaggcagacc agccagcagc
    15901 actaaaatat ccagaaccta gagactattt tcttcatact cgtgaaggtg atgttattta
    15961 tgatgaggat ataaaaagat attttgagga tttagaagcc tatttaacag ctagacttgg
    16021 tgggattgat aaaaaagtag aagaagctgc ccaaaagcca ggtattccag gtcctactgg
    16081 ccctcaaggt cctaagggag acaaaggaga tccaggtgcc cctggtgagc gcggtccagc
    16141 tggaccaaag ggcgatacgg gcgaagccgg accaagaggt gagcaaggcc cagccggaca
    16201 agctggagaa cgtggaccaa aaggagatcc aggtgctcca ggtcctaaag gtgaaaaggg
    16261 tgatactggt gcagttggtc ctaaaggtga aaaaggtgat accggagcaa ccggaccaaa
    16321 gggagacaag ggcgaacgcg gtgaaaaagg cgagcaaggc caacgtggcg aaaaaggcga
    16381 gcaaggccaa cgcggtgaaa aaggcgagca aaaaccaaag ggtgatcaag gaaaagatac
    16441 aaaaccatca gctccaaaag cacctgaaaa ggctcctgca ccaaaagctc caaaggcttc
    16501 agagcagtca tctaatccta aagcaccagc tcctaagtca gcaccaagca aatcagcggc
    16561 accaacaggt caaaaagcag ccctaccagc aacaggggaa atcaaccacc cattcttcac
    16621 ccttgcagct cttagtgtca tcgctagcgt aggcgtccta actctaaaag gaaaaaaaga
    16681 ctaagctagt tattgtatct ttcctgtatg acactagcta acagctaatc acaaacacca
    16741 gagagaggtc ttttctgacc tctcttttat atacactgag cacatgctta cctcaaaaag
    16801 acagtagtct aagtttgact actgtctcaa aaatcatttt tatctaaagc tttgatcagc
    16861 ttgacaaatg gtagagaagg acttgatttc taaggccttt gacctcagtt tgacttttgt
    16921 taattttcct tacgttttat agctgctaca ccagctgtag ccataactgc aagtgcagct
    16981 gcggtgaaga atgggttcac agcctcacct gttgctggca attgattagt cgttttcttc
    17041 atctcagctt tagctgctgc tgctttagaa gctgtgtgag ctggcgctgc tactttacct
    17101 gcttgatcag ctttttcagg actgagtggt ttagcctctg gcttagtttc tggtttggtt
    17161 tctggaactt taggtgcgtc ttcttgtggt tttgaatgtg gacttgattt tttaatatct
    17221 ttagcatcta gggcaacgct tctttcctca cctgttgtag cttgagaaag ctttttgccg
    17281 ttgacaaaaa tctcatagaa agtgccatct agaagccctt tagaaaatac agctttgcca
    17341 tcagctcctg ttgttacttt ctctatcaca cgacctactc tatgctttag agtgacttct
    17401 tgtcctgata aaggttcagc atcttcatta cgaacgataa caaccaaagg tgttttactg
    17461 tattctggct caactgttcc ttttccgtca acagtaaagc tagctgaatg cttgtcgcca
    17521 tcaacacctg ttcgtacagt atagccttga ggaacgccat tcacaaaaat tgataaactt
    17581 cttcctaaag gaagcttgtc aaaaacagct tgtccttttt catctgttgt cacagtcgca
    17641 agtgtttttc tgccacttgt tatatctacc acttggacgt cttttccaga taatacttta
    17701 ccctcagggt ctataactgt tgcggtaaaa gcaaagctac cttcaataac atcatcatga
    17761 tggtggtgtg catgatcact gtgatgacta ctctgcccat cgtcaaaagg cttagaaaca
    17821 tcaatcttat ccaataaaat aacatgatga tgatcgtcat gtggatacat caaggcctta
    17881 ccctctgaag tatccaataa ttgaatcttg tctaatggca agcctgtatt tttggcgata
    17941 taagcttttt ttacggcaat aatatcttca gctgattgat tagtgtctag cggtaattta
    18001 tcagctgctg ctacaggatt tgcggtttct gatgcttttg taattggttt atcagccatc
    18061 acctcagtgc tgtcagataa ctgttgatta gctgtatctg cagtatcttt atcctcacct
    18121 aacctcggtt ggactacagt gtgattatcc actgctggtg attcatcagc aaatgctact
    18181 gacgagttag ttgacatcgc taaaccagca gccattaaag cagctgggat aagtaaagag
    18241 tatcgggtaa cttgattctt tttca
//
LOCUS       DARYXS010000036        17955 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.037, whole genome shotgun sequence.
ACCESSION   DARYXS010000036 DARYXS010000000
VERSION     DARYXS010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17955
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.037"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            18..1676
                     /locus_tag="TV193_001008"
     CDS             18..1676
                     /locus_tag="TV193_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1513211.1"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRADAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPKGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKAAEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKD"
     gene            1845..2759
                     /locus_tag="TV193_001009"
     CDS             1845..2759
                     /locus_tag="TV193_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513212.1"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNSPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLAVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILATDMIISIADPRVRLG"
     gene            2769..3800
                     /locus_tag="TV193_001010"
     CDS             2769..3800
                     /locus_tag="TV193_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513213.1"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYADQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIRIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASIGSLITDAQESLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            3812..4858
                     /locus_tag="TV193_001011"
     CDS             3812..4858
                     /locus_tag="TV193_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513214.1"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRDISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGNICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQSQTASSIIFITHDLGV
                     VAGMVDRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            4858..5793
                     /locus_tag="TV193_001012"
     CDS             4858..5793
                     /locus_tag="TV193_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1513215.1"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQNHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERKRIAEVYDPS
                     QELDGQERQMHEITPGHFVLATQAEAEQYRAECGL"
     gene            complement(6422..8104)
                     /locus_tag="TV193_001013"
     CDS             complement(6422..8104)
                     /locus_tag="TV193_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1513216.1"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(8106..8336)
                     /locus_tag="TV193_001014"
     CDS             complement(8106..8336)
                     /locus_tag="TV193_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEL1513217.1"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EHTDYNVEFIELLSDKHLDYEKETGVFTLTEF"
     gene            8622..9320
                     /gene="tsaB"
                     /locus_tag="TV193_001015"
     CDS             8622..9320
                     /gene="tsaB"
                     /locus_tag="TV193_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEL1513218.1"
                     /translation="MKTLAFDTSNKALSVALLDDGTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLAELVSCDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            9323..9748
                     /gene="rimI"
                     /locus_tag="TV193_001016"
     CDS             9323..9748
                     /gene="rimI"
                     /locus_tag="TV193_001016"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEL1513219.1"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMGQLDGFEGVIFLEVRASNH
                     RAQQLYLKHGFEVVGQRSNYYHDPIEAALIMRREGKNDR"
     gene            9738..10754
                     /gene="tsaD"
                     /locus_tag="TV193_001017"
     CDS             9738..10754
                     /gene="tsaD"
                     /locus_tag="TV193_001017"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEL1513220.1"
                     /translation="MTDRYILAVESSCDETSVAILKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLKSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAEEITDIAVVIPPLRLCGDNAGMIALAAVVEYEKGHVAGLDLNAKPSLAFDS
                     FHQQ"
     gene            10776..11804
                     /locus_tag="TV193_001018"
     CDS             10776..11804
                     /locus_tag="TV193_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEL1513221.1"
                     /translation="MFYLLLPPLICSVVFLAVYIKEPRTLWLGASFVTTLGVSLLCAM
                     IYIFSIEEKLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSFRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLILYLLLIVSVYTISSMLNT
                     FYFRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQIYQKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAIQQGIKSEDILVENQSRNTRENILLSKQLIPSGASFCLVTNRYHLFRA
                     LLLAKELALPCRCYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            complement(12199..12468)
                     /gene="rpsN"
                     /locus_tag="TV193_001019"
     CDS             complement(12199..12468)
                     /gene="rpsN"
                     /locus_tag="TV193_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEL1513222.1"
                     /translation="MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSN
                     PNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW"
     gene            complement(12662..13834)
                     /locus_tag="TV193_001020"
     CDS             complement(12662..13834)
                     /locus_tag="TV193_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1513223.1"
                     /translation="MILYDTIIIGGGPAGMMAAISSSYYGYKTLLLDKNKRLGKKLAG
                     TGGGRCNVTNSGSHDELIAGIPGNGRFLYSVFSQFDNHDIIAFFKENGVTLKEEDHGR
                     MFPTTDQSKTIINALEQKIKSLGAQVLISTEIVSVKKRNNLFYLKSVDQTFSCERLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLADVTLSC
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKTLMPERVADFLAKGYPEKGKQLTPTQTQELVNRIKQLPIPITGKISLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDVNAHTGGFNITAALCSGWVAGSSQS"
     gene            13960..14490
                     /locus_tag="TV193_001021"
     CDS             13960..14490
                     /locus_tag="TV193_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEL1513224.1"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            14535..15122
                     /locus_tag="TV193_001022"
     CDS             14535..15122
                     /locus_tag="TV193_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEL1513225.1"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLDAFKQFVGDTPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAIADNPFAALGGLFD"
     gene            15226..15948
                     /locus_tag="TV193_001023"
     CDS             15226..15948
                     /locus_tag="TV193_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1513226.1"
                     /translation="MSDIYSTGELAKAAGVTVRTVQYYDKRGILLPSQLTEGGRRIYT
                     ESDLERLKIICFLRDLDFSIEQIKRVLAEDNVMAVLDLLLVDHIQQLEQDLRTKKHQL
                     DTAVKLLSGIRCSSSHSIKNLSDMSLTMNNQKAWRRLQLKMFSNIALAILVHVMLVLL
                     TSYFHLSWLVWIEAPLWIIFFTLLIVYFRKQFEYLCPNCHTIFEPDFKEFALAGHTPR
                     TRRLTCPHCHQKSYCLELAKEK"
     gene            complement(15990..16289)
                     /locus_tag="TV193_001024"
     CDS             complement(15990..16289)
                     /locus_tag="TV193_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEL1513227.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFT
                     GDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF"
     gene            16687..17274
                     /locus_tag="TV193_001025"
     CDS             16687..17274
                     /locus_tag="TV193_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513228.1"
                     /translation="MTTTKQSKTTLAARYLKLGLTSAMFAGGAFLALGSAPAVSASTH
                     AGNDQPATQRLTDQEIYERAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAP
                     QPPAAPQLTDQDAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQ
                     LTDQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY"
     gene            17413..>17955
                     /locus_tag="TV193_001026"
     CDS             17413..>17955
                     /locus_tag="TV193_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1513229.1"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIISDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYER"
BASE COUNT         4966 a         3627 c         4205 g         5157 t
ORIGIN      
        1 gttaggagga aggttatatg acagtactag gaacaaaagc atgtaagcgt ctgggcttag
       61 cggcagttac gctagcctct gttgctgcct tgatggcttg tggaaataag caatcagcgt
      121 caacagacaa aaagagtgag attaattggt atacgccaac tgagatcatc acacttgata
      181 tctcaaaaaa tacagatacc tattctgctt tggctattgg taattctggc agtaaccttt
      241 tgcgtgctga tgctaagggg aaattacagc ctgatttggc tgaaaaggtt gatgtgtcag
      301 aggacggctt gacctataca gcaaccctgc gagatggctt gaaatggtct gatggtagtg
      361 atctaacagc agaggacttt gtgtacagct ggcagcgaat ggtcgatcct aagacagcct
      421 cagagtacgc ttacttggca actgagtcac atctgaaaaa cgcagaggac attaatagcg
      481 ggaaaaatcc tgatctagac tctctagggg taaaggctga tgggaataag gttattttta
      541 ccttaacgga gccagcacca caatttaaga gcttgctgtc cttctctaac tttgttcctc
      601 aaaaagaatc ctttgtcaag gacgctggca aggactatgg gacaacatca gaaaaacaaa
      661 tttattctgg tccttatatt gtcaaggact ggaatggcac tagcggaacc tttaagctag
      721 taaagaataa aaactattgg gacgccaaaa acgtcaaaac tgagacagtt aatgttcaaa
      781 cggttaaaaa gccagataca gctgttcaaa tgtacaagca aggtaagcta gactttgcaa
      841 atatttctgg tacctcagct atttacaatg ctaataaaaa gcataaggac gttgttccgg
      901 ttcttgaggc aacaacagcc tatatcgtat ataaccagac aggagctatt gaaggcttga
      961 acagtcttaa aattcgtcaa gccttgaatt tggcaacaga ccgtaaggga attgtatctg
     1021 cggctgttga tacaggctca aagccggcta cagcgctggt tcctacaggt cttgctaaat
     1081 tatctgacgg aacagatcta acagagcatg tggcacctgg ctataaatac gatgacaagg
     1141 aagctgcaaa gctcttcaag gaaggcttgg cagagctggg caaggatgcc ttgacaatca
     1201 ccatcacagc tgatgctgat gcgccggctg ccaagtctgc agtggattac atcaaggaaa
     1261 cctgggaaac agctcttcct ggcttgaccg ttgaagagaa atttgttcct ttcaagcaac
     1321 gtcttgagga tactaaaaac caaaactttg aggttgcagt tgttctttgg ggtggtgatt
     1381 atccaaaagg gtctaccttc tatggcttgt ttaaatcagg gtctgcttat aactatggta
     1441 aatttacgaa tgcagactat gatgcggcct acaacaaggc tctaacaaca gatgccttga
     1501 atacagatgc ggctgctgat gattataagg cggcagaaaa agccctttat gacaatgccc
     1561 tttacaatcc cctttacttc cgtagcggtg aaggcctgca aaatccaagc atcaaaggtc
     1621 ttatccgtaa ttcaactggt ctaaatgttg actttactta cgcttataag gactagcaat
     1681 aatattattg taagcctata ctgacctagc aaggccacag ctccttgatg ggaagtgttt
     1741 aagagaagct tagggctagc taggagtgtc tatcctgtag gccttggcaa gcatattgca
     1801 agaattggtc ttaaccagtt cttgcttttg gttagaggaa aaatatgatt aaatatcttt
     1861 tgaagcgagt ggctatttta gtagtgacac tctgggtggt gattaccctg tccttctttt
     1921 tgatgcaggt gatgcctgga acaccctata acagtcctaa attaactgat gacatgattg
     1981 ctatgctgaa tcagcagtac ggcttagata agcctctttg gcagcaatat ttgaagtatt
     2041 tgtttgatat tcttcatggt gactttggca ccagctatca gtcgattaat caatcagtga
     2101 caaccctgat ctcgcagcgt ctgggggtat ctgtgcactt aggagtacag gcgcttattg
     2161 ttggtattag ctctggctta gctgttggtg ctgtctcagc gcggaataaa aataatagca
     2221 ttgatgccat tttaagtgtt atctcaacgc ttggtatttc catgccgtcc tttatcattg
     2281 gcttgctgct gctggattat ttgggcttta aatggaattt acttcccttg tctggctggg
     2341 gaagctttgg gcaaacgatt ttgccgacgc ttgctttagc tattccggtc tttgctcagg
     2401 tgacccgttt tttccgcagc gagatgatcg agaccttatc gacagattat attcagctag
     2461 ctagggcgaa gggcttgact aagcgtcagg tgactcgtcg gcatgcttac cgcaattcga
     2521 tgattcctgt gttaaccttg gttggtccga tggctgctgg tattttgacg ggatcagccc
     2581 tgattgagca gattttttcc attccgggga ttgggcagca gtttgtgacc tctattccca
     2641 ccaaggatta cccagtgatt atgggaacaa cgattgtcta tgcgctaatg ctgatggttg
     2701 ctattttggc aactgatatg atcattagta tcgcagatcc acgtgttcgt ttgggatagg
     2761 agagtgctat gctagaagaa acaaaatcat ttaagcttgt tggagcaggt agcttagcga
     2821 cacaagaaaa aattgaaaag ccggcgcttt cctttcttca ggacgcttgg cgtaggctaa
     2881 agcacaataa actagctgtt attgcgatgg ggtttttagc tgtgctgctt ttgttttcta
     2941 ttggttcttt atttgttgta tctacagatg atgccaatag ctttaacagt aaggaggtaa
     3001 gcatataccg taacctgccg ccaaagctaa gcagcagctt gccattttgg aatgggacca
     3061 ttacctacgc tggtaataca gagcccaatg acgcttatgc ggatcaaggg gtcccagagg
     3121 acaaggcctt cttactcggg acggataatc tggggcgcag tattggaaaa cgtattacgg
     3181 tagggattcg tatttctctt ttgattgcta ttgtcgcaac cctgatcgat ctagtgattg
     3241 gggtaaccta tggcttggtc tcaggctttg ttggtggcaa gactgacatg gtgatgcagc
     3301 ggatcattga gattatctcc tctattccaa accttgttat tgtgaccatg cttggtcttt
     3361 tgcttggcaa tggtgtgact tcaattatta tttcaattgc gattgtaggc tggacctcaa
     3421 tggctaggca ggtccgcaac ctaaccctgt cttatcgaga gcgtgatttc gtccttgctt
     3481 ctcgtgcctt gggagaaagt aatatcagga ttgcctttaa gcatgtattg ccaaatattt
     3541 cagggattat tattgttcaa atcatgatga ctgttccgag tgctatcatg tatgagtcag
     3601 ttttatctgc gattaattta ggcgttaagc caccgacagc ttcgattggt tcattgatta
     3661 ctgatgcaca agaaagcctg caatattatc cttatcaggt gctgctgccg gcttttgcct
     3721 tggtgttaat ttcgctagcc tttattttgt tgggtgatgg cttgcgtgac gcttttgatc
     3781 caaaatcaag tgatgaatag ggggaaataa aatgacgaat gaaaccattt taagtgtcaa
     3841 aaacctccat gttgatttta aaacctacgc tggagatgtt aaggcgattc gtgatatcag
     3901 ctttgagcta aaaaagggag agactcttgc gattgtggga gaatcaggct cagggaaatc
     3961 tgtaaccact cgcacgctga tggggttaaa tgctaagaat gcaagtattt cagggaatat
     4021 ttgctttaag ggcaagcagc tcaatgagct gaaggaggag gaatgggtca aggtgcgtgg
     4081 caatgaaatt gcaatgatct tccaggatcc gatgaccagc cttgatccta ccatgacaat
     4141 tggcatgcag attgcagagg caataatgat tcatcaaagc attcataaga cagaagcctt
     4201 gaagcgtgct ttagacctga tgcgtcaggt tggtatccca aatgctgagg agcaccttaa
     4261 ggattaccca catcagtggt ctgggggcat gcggcaacgg gctgttattg ccattgctct
     4321 agctgccaat cctgatattt tgattgcaga tgagccgaca acagctcttg atgttaccat
     4381 tcaggcccag attttgaagc tgatgaagga tattcagtct cagaccgcat catcgattat
     4441 ctttattacg catgaccttg gtgttgttgc tggaatggta gatcgcgttg ctgtcatgta
     4501 tgctggaaag attgtcgaat atggaacggt tgacgaggta ttttatcatc cgcagcaccc
     4561 ttatacctgg ggcttgctca attcgatgcc aacaacagct actgcagcag gtagcttgag
     4621 gtctattccc ggaacgccgc cagatttatt aaaccctcca aagggagatg cttttgctgc
     4681 ccgtaatgag tttgccctag acattgacca tatcaaagag cctccaatgt tcaaggtaag
     4741 tgacagccac tacgcagcaa cctggttgct agatgagcgt gctcctaaaa taacccctcc
     4801 attcccaatc cgcaagcgtt gggcaaaatg gcaggaaatg gaagagagga aggcttaatg
     4861 acagaagctc gtaaaaaatt aatcgaagta aagaatgttt ccttaacctt taacaagggg
     4921 aagaaaaacg aggttaaggc tattgatcgc cttagctttg acatttatga gggggaagta
     4981 tttggccttg ttggggaatc aggctcaggc aagacgacag ttggtcgagc tattttgaaa
     5041 ctgtatgaca ttagtgatgg tgagattatc tttaacggag aaaatgtctc ccaattaaaa
     5101 gggaaaaagc tgcatagctt tcgtaagcat gcacaaatga tcttccaaga tcctcaggct
     5161 agtttgaacg gccgtatgaa aattagagac attgttgcag agggcttaga cattcatggc
     5221 ttgacagcct caaaggcaga gcgtgaagca agagtccagg agctgttaaa gcttgttggg
     5281 ctcaatcaga accatttgac gcgctaccca catgaatttt ccggtggtca acgccagcga
     5341 attggcattg cgcgtgcctt ggctgtgaag ccgaccttta ttatcgcaga tgagccgatt
     5401 tcagcgcttg atgtgtcgat tcaagcacag gtagtgagtc tcatgcagca attgcaaaaa
     5461 aagcgtggct tgacctatct ctttatcgct cacgatttgt ctatggtcaa atacatttca
     5521 gaccgtattg gtgtgatgca ttggggcaaa atgcttgaga ttgggacatc tgatgaggtt
     5581 tacaatcacc cgattcaccc ttatacgaaa agcttgatct cggccattcc tgagccggat
     5641 cctgaaaagg agcgtaagcg tattgcagag gtttatgatc ctagccagga gctagatggc
     5701 caagagcgac aaatgcatga aatcactcct gggcattttg tcttagcgac tcaggccgaa
     5761 gccgagcagt accgagcaga gtgtggcctt taagagacta gcataacagc aatttcctaa
     5821 aaaggctgat gtgatagttt tttaggtatg acagaccaaa agtcgtatga cctttgccga
     5881 tcaaaagcag gtgccatgcg attttggtgg tatggtggag ctttgtcagc caacctagac
     5941 tgcacaaaaa gctccttatg atagaatttg tagcatgagg ttgcgacaca agtctaccct
     6001 aaaataaaac aaaataaaac aaccgaacag gtctagcttt ctgagatttc aaaagccaga
     6061 cctgttcggt ttttaatgaa tgagactagg tcataaagta tcttagttaa gattgtctaa
     6121 agtgcagctc tttttgctgt gcttgctgct gtttttataa aatgactcgt gggaatcaat
     6181 cagcctgtag tcaaatgtta tcgctctctt tttgagatgt ggcttgacag gtttgctaag
     6241 ctcagcaggc tatttttagt agtatagcta gacaaaggcc cttaagctag ctcagcacgt
     6301 cactctgtta agcttagcta acagcacgtg ttgggcaagt agtatgcctc atagccttgt
     6361 acgtcagtca ttgacgttga cgcaacaaaa aaacacgagt ctctaagctc gtgtcaaaga
     6421 tctattggct atcaggcgtt agaaccatcg gaatgataat aggctcgcgc tctgtctttt
     6481 cgtaaaggaa gggacgaagc gcattaacga tagcaccatt gacagactgg atactagcgt
     6541 ccttattttt cagagcgata cgaatcgcat tgaaaagcac gcgctgactc tctctgatga
     6601 gctcgcctga ctcgcgcatg tagataaagc cgcggctgag aatatctggt ccggctaaga
     6661 tcatctgtgt ctcaaaatca acagtcgcca ctgcaaggac aaccccgtcc tctgaaagat
     6721 cacgacgatc gcgaaggact gctgtcccaa tatctccaat gccattgcca tctacataaa
     6781 tgtcctgagc attgaaatga ccggctatac gagcgctatc actggtcaag gccaatacgt
     6841 caccattttc catgataaag atattttcct ctggaatccc aatatcaaca gcaagcccag
     6901 catgaacctt ctgcatacgg tattcaccat ggacaggcat aaagtatttt ggcttaataa
     6961 ggctaagcat tagcttttgc tcctgctggc caccatgacc ggaggtgtgg atattgttga
     7021 cctttccatg aataacgtca actccagcct cctgaatcgt attgattagc ttattgacgc
     7081 tgacggtatt accaggaatt ggacttgatg aaaagatgac agtgtctcca ggctgtaagc
     7141 tgacctgtct gtgggtacca ttggcaatcc tagcaagggc ggccatagac tccccttgac
     7201 tgccggtaca catgatcaaa atctcactag cgtggtaatg tttaatctca ttaggctcaa
     7261 taaaggttcc ctttgggacc ttgatgtagc caagctcaat accgttaaca atagcctttt
     7321 ccattgaacg accaaataca gcaatcttac gccctgtctt aacagcggct tctgcagcct
     7381 gctgcaagcg gtagatattt gaagcaaagg aagcaaaaat gatacgtcca tgaatgcctt
     7441 caataatgtt catgattgac tggccaacga ccttttcaga attcgtaaag gttggtatct
     7501 cggcatttgt cgaatcggac aatagacaaa gaaccccgtc cttaccaaga gcagccatgc
     7561 gatgtagatc agccggatca ccaacaggtg taaagtcaaa cttgaagtcg ccagtacaga
     7621 tgactttccc ttgtggggtg tggataacaa tcccaagtgg ctctggaata gagtgagttg
     7681 ttttaaagaa ggtaacgctc atatgcttaa aggtgagctc ggtattgtga ttaatctcat
     7741 agagcacagc atcgcgtaag agaccgtgct cctccagctt tcctcggata agagctagag
     7801 ctaaggggcc tgcatatata ggcacattag cttgctttag taaaaaagga ataccgccaa
     7861 tatgatcctc atgaccatga gtaatcacaa gagccttgac gcgctccaaa ttgtcaacaa
     7921 tataagagta atcggggata acatagtcaa tccctagcag atcgtcctct gggaatttga
     7981 taccggcatc gacaatgatg atttcatctt gatactcaat accgtaggtg tttttgccga
     8041 tctctcccag accaccaatc gcataaaccc caacctcatt aggccttaaa ctgatatttg
     8101 tcatgttaaa actccgttaa tgtgaaaaca ccagtttctt tttcgtagtc taggtgcttg
     8161 tctgagagca gctcgatgaa ttcgacattg taatcggtgt gctcttcaac catcttgcgg
     8221 gctttgatac gcccctcaag ctcacttgca gcgtctatat ctaggtatag ggcctgtgtg
     8281 ttttcacgac gcggactgcg ttcctttgtt tcttggtaga aaactttata aatcattgat
     8341 gatatcttcc tttcatgatg aatcgattat ccaaacaata acaaataggt caaaacgaga
     8401 aggcctctgt tttgacgatt acctatcatg tgattattgt gtaatagatt taaacctgat
     8461 tctgtgcaat tactaagatt ataccatact atcggctttt agtaaaaagt ttcgataaaa
     8521 ttattctctt gaccggtgat gaggctgtgg ctgtctcctt ttccatgacc tttattttat
     8581 gttataattg tggaatagaa atgacttgag aagggcttag tatgaagaca cttgcatttg
     8641 acacatcaaa taaggcatta tctgttgctc tattagacga tggcacatta ttggctgatc
     8701 ttacgattaa tgttaagaag aatcacagta ttagtctgat gccggctatt gattttttaa
     8761 tgtcctcagc tgacctgaag ccaaaggatc ttgatcggat cgtagtagca gaagggccgg
     8821 gctcctatac tggcttgcgt gttgctactg ctacagcaaa aatgcttgct tatagcctaa
     8881 gtattgacct cgttggcgta tcaagcctat atgccctagc ggcttctact tgccgagaaa
     8941 accctgatag cttggttgtc cctttgattg atgctagacg acgccatgtt tatgtgggct
     9001 attatcacca tcaaaaagct gtgaaacagg ataagtacgc gtcctttgat gctgttttag
     9061 cagaactggt ctcttgtgac catgtgattt ttgttggaga agtggagggc tttgcagagg
     9121 acattcgatc agccttgcca gaggccaaga taaagccaag tctgccatcg gcttttgagg
     9181 ttggtttgct aggcagcagc ctttcagctg acaatgtagc agcctttgtc ccacaatatt
     9241 tgaagcgggt cgaggcagag gaaaactggc tcaaaactca tgctgccggt gatgacagcc
     9301 agtatgtcaa gcgagtttag cgatgatgtc tatccaagaa aaagcagcag ctgtctatca
     9361 ggtgctaaaa gaggtctatg gtcaatcccc ttggacctta aagcagatag tgtctgatat
     9421 gcagcaggag catgttgatt attttacctt ttatcatcag gagaccctgc taggtttttt
     9481 agcgattcaa cagctgccag gagaaatgga aatcactaat ctagctgttt tgccaagcta
     9541 tcaggggcaa gggattgcct cttggctcat gggacagcta gatggctttg agggagtgat
     9601 atttcttgag gttagagcgt caaaccatag ggcgcagcag ctttacctta agcatggctt
     9661 tgaggtggta ggccagcgta gcaattatta tcatgatcca atagaagcag ccttgatcat
     9721 gaggcgggaa ggaaagaatg acagatagat atattttagc agtggagagc tcttgtgatg
     9781 agacaagtgt tgctatctta aaaaacgaca acgtcttatt gaccaatatt attgctagtc
     9841 aggttgaaag tcacaagcgt tttggtggag tggttcctga agtggctagt cgtcatcatg
     9901 tggaggtgat tacgacttgc tttgatgacg cactcaagga ggcccagctt gaggcttctg
     9961 acttgactgc ggttgcggtt acctatggac caggtctggt gggggccttg ctagttggcc
    10021 tagcagcagc caaggccttt gcttgggcta atgatttgcc cttgattcca gtcaatcata
    10081 tggcagggca cctgatggcg gcacgcgagc aaggagagct ggaataccct cttatggctc
    10141 tcttggtttc tggtgggcat acagagcttg tctatgtgac cgagccagga gaatatcata
    10201 ttgttggaga aacacgtgat gacgcagttg gtgaggccta tgataaggta ggacgtgtga
    10261 tgggcttgcc ctatcctgct ggtcgtgaga ttgatcagct agctcaccaa gggacagata
    10321 cctatcattt tcctcgtgcc atgatgaaag aggatcattt agaattttct ttttcaggcc
    10381 taaaatcagc ctttatcaac ctgcaccata atgcgcagca aaagggtgag gagcttgtgc
    10441 ttgaggatct ctgtgcttcc tttcaggctg cggtgttaga tatattgtta gcaaaaacga
    10501 agaaggcact caagcagtat ccatcaaaaa tgctagtcgt tgcaggtgga gtggcagcta
    10561 atcagggact tcgtgagcgt ttagctgagg aaataactga tatagctgtt gtgataccac
    10621 ctctaagatt gtgtggagat aatgctggta tgattgcgtt ggcggcggtg gttgagtacg
    10681 agaaagggca tgtggcaggc ttggatctaa atgctaagcc gagtctagcc tttgatagct
    10741 ttcatcagca gtagtattag tatgaggaga ttgtcatgtt ttatttattg cttcccccat
    10801 tgatttgcag tgtggtattt ttggctgtct atattaagga gccaagaacg ctgtggctag
    10861 gagctagctt tgtgacgacc ctaggtgtta gtctcttgtg tgctatgatt tacatttttt
    10921 caatcgaaga aaagcttcag ggagttggta tcctagtgct aggtgttatt gggtttcttg
    10981 cgattgtatg gttgatgtct agtcccttta tcctcttgct ctttctaagc tttaatggca
    11041 ttaggctcat caaaagagag gggctttcct ttcggaattt attgctgatt ggctcagcgg
    11101 tgctattgtt tgtacatcct tttatcagca gactattgtt agagagtatc ggtgattcaa
    11161 agcttttaag gatcatgtat gaaacgagtg acctcttaat cctttacctc ttgttaatcg
    11221 tatcagtcta caccatctca agcatgctga atacctttta cttcagaaaa accaaggagg
    11281 attatattat tgtgctgggc agcggcttaa atggagacca ggtcaccccc ttgctagcta
    11341 gccgcattaa taagggcatt cagatttacc agaaaaatcc tggcagcaag ctgatcatgt
    11401 ctggtggcaa aggggctgat gagctaatag ctgagggtga ggcgatgtgt cgctatgcaa
    11461 tccagcaagg aatcaaaagt gaagatatat tagttgaaaa ccaatccaga aacaccagag
    11521 aaaatattct gttgtctaag caattaatac catctggagc ttccttttgc ttggtgacca
    11581 atcgttacca cctgtttaga gccttattac tggctaagga gctagccttg ccttgcaggt
    11641 gctatggggc aaaaacaaag ctctacttta gtatgaatgc ctttatcaga gagattgttg
    11701 gctatctcca attaaagaaa aagcagcacc tgctggcaat gctcatctta acagtaggct
    11761 atatagccat aagagtggtg atgatctata tgctgcacat ttgatgtcat tggcaaaaaa
    11821 gctaaggcta gtcacctcgt cttgggctga aaaagtctct cttaggtcct tttctcagat
    11881 gatatgagca agcagccttt ttaaaaaggc tacatctagg attttatgga gccttagagc
    11941 ttgttgtgtg gtgatgttca atggaaccaa tcacaattgt tacagcaaaa agcaggcctt
    12001 taggaacgtt tgctttgctg gtaagtcctt ttacttgcag aggctggcta caccagccaa
    12061 aggctaaggc aagtgattta gcttgtgatg atcaaggagt tttaagacgt aaaaaaatag
    12121 ctcggtatct tggcataccg agctatcatg ataaattggc ttctatgatt actaaatctt
    12181 aaacaaggtg agtcaagctt accagctagc cttagtgatt cctggtagtt ggcctttgtg
    12241 agctagctca cgaaaattga tacggctgac accaaactta cgcatgtaag catggggacg
    12301 gccatcaatt ctatcacgat ttttcaagcg atttggattt gaatcacgtg gcaatttgcg
    12361 cagtgcttca taatcaccct ttgctttaag ctcgcgacga aggtcagcat actgttcaat
    12421 cagttggagc tgcttatggt atttagcaat ttttgacttc tttgccattg ctttctcctt
    12481 cttaatattt aataatctca gagcgttatc agcaccctga atttcctcaa ccagtcatta
    12541 atcagttaag aaaacatagc tctattatac actaatttca atcaaatgca agaaaaatag
    12601 ataactgatt aaccagttga ggcaaaaaca gcctgccagt gagtctactg acaagcctag
    12661 cttagctttg cgagcttcct gccacccagc cagagcagag ggcagctgta atgttaaagc
    12721 cacctgtatg agcattaaca tctaagacct caccagcaaa gtaaagtccc gcgacctttt
    12781 tgctttctag ggtcttaggg ttgatttctt ttaagtcaat gccacccttg gttacaaagg
    12841 atttggccag agatattttt cctgtgattg gaatcggtaa ttgcttaatc ctgttgacga
    12901 gctcctgagt ctgtgtggga gttaactgct ttcctttttc tggatagccc tttgctaaaa
    12961 aatcagcgac tcgctcaggc atcaaagtct tgagcgcatt tttaagggcc ttttcccggt
    13021 gctgcgctag atagctgagc agctcagctg cggaggtttg tggcagcagg tcaagctctg
    13081 cgatgtcacc tcccttaaca aaggaggaaa gcctgagagc agcggggcct gacaacccaa
    13141 aatgggtaaa aagcaaatcg tgagtgatct gatgtttccc acagctaagg gtcacatcag
    13201 caagtgaaat cccctgcaga gccttatgtg gaaagtctgt taataagggg ctttccgcag
    13261 cctctagctc ggtgacagct atgttaaagt ggcgagcaat atcatagcca aagcctgtcg
    13321 atccagtaga tgggtaggac ttgcctcctg ttgccacgat aagcctctcg cagctgaagg
    13381 tttgatcaac tgatttgagg taaaaaaggt tattccgctt tttgaccgag acaatctcgg
    13441 tactgatcag cacctgagct cctagtgact tgattttttg ctccagcgca ttgataatcg
    13501 tctttgattg atcggtcgta ggaaacatgc gtccatgatc ctcttccttg agggtcaccc
    13561 cattttcctt gaaaaaggca atgatgtcat gattatcaaa ttgggaaaag acgctataga
    13621 gaaagcgccc gttaccggga atgcccgcga ttagctcatc atggcttccg ctattggtga
    13681 cattgcagcg tcctcctcca gtccctgcta gctttttgcc taggcgcttg tttttgtcaa
    13741 gtaggagtgt cttgtagcca tagtagctac tagagatggc tgccatcata ccagcaggac
    13801 cacctccaat aataatcgtg tcgtatagta tcatgtgctt attttagcat aacatcaagc
    13861 gatttaacag taatgtaaac taggctaaat tgacagaatt ctggtattgt gttactattt
    13921 ttaataagaa tattcagtta cagtaataaa gaggaaatta tggcaataga aaagacagtt
    13981 agtgaactag ctgacatttt gggagtgagc cgccaggctg tcaataatcg tgtcaagtcc
    14041 ttaccagagg aggaccttga taaaaatgat aaaggggtca ctgtcgttaa gcgtagtggc
    14101 ttggttaagc tggaggaaat ctacaagaaa accatttttg atgatgagcc aattagtgaa
    14161 gagaccaagc agcgtgagct cttagagatt ctggttgacg aaaaaaacac tgaaatcact
    14221 cgcttatatg agcagctaaa ggcaaaggat agccagctgg ctgctaagga cgagcagatg
    14281 cgtattaagg acgttcagat tgccgagaag gacaagcagc tggatcagca gcagcagctg
    14341 acagctaagg ctatggcaga caaagagacc ttgaagctgg agcttgagga agcaaaggct
    14401 gaggctgatc aggtacgact gcaagcagag gagatacagt ctgaaatggg acctaaaaaa
    14461 ggttttttaa atcgtttatt tggtaaataa cagtatacca agaccctcta agggtctttt
    14521 ttgaggagag aagaatgaaa caattagaag catatattgc ctttgatatg gaatttaata
    14581 ctgtcaatga ggttagtcat atcattcagc tttcagcggt caaatggcac aagcatcagg
    14641 aggttgacag ctttgacagc tatgtttaca ctgctgttcc cctgcaaagc tttatcaatg
    14701 gcctgacagg cattacctca gataagatcg tatcagcacc caaggttgat gaggtgcttg
    14761 atgcctttaa gcaatttgtc ggtgacacgc ctttgatagg ctataatgca caaaagtctg
    14821 atttgcctat tttagcagca aatggcttgg atctgtcagc gcaatatgca gtcgatgtct
    14881 ttgatgaagc ctatgagaga cgaagcagcg acctaaacgg gattgctaat cttcgcctgc
    14941 aaacagttgc tgatttttta gggataaaag gaagaggaca taatagctta gaggacgctc
    15001 gtatgacagc gcgtgtctat gaagcgtttg tggaatttga cgacaataag tcttacctaa
    15061 acaaacaaaa agaagcgatt gcagataacc cctttgcagc tctgggaggg ctttttgact
    15121 agcagcgcta gtcatttctc tgaaaaagaa aaatgaccta aggtcagggc ttgcttgtga
    15181 ccttgggtca tattctataa tgaggacaga aaggaggtga aggacatgtc tgatatttac
    15241 tcaactggtg agctagcaaa agcagcaggt gtcactgtca ggacagtgca atattacgat
    15301 aagcgtggga ttttgttgcc ttcccagctt actgaaggtg gacggcggat ttacaccgag
    15361 tcagatttgg agcgattgaa aatcatttgc ttcttacggg acctagattt ttccattgag
    15421 cagattaagc gcgtgctagc agaagacaat gttatggcgg tgcttgacct cttgctggtg
    15481 gatcatatcc aacagctgga acaagactta aggacgaaaa agcatcagct tgacacagct
    15541 gtcaagcttt tgtcaggtat tcgctgctca tctagtcact ctatcaaaaa cctatcagac
    15601 atgtcactta ccatgaacaa tcaaaaagct tggcgtcgtt tgcagttgaa aatgtttagt
    15661 aatattgccc tagcaatatt ggttcatgtg atgttagtgt tactaactag ctattttcat
    15721 ctatcttggt tggtatggat agaggctcca ctatggataa tcttttttac tttattgatc
    15781 gtttattttc gtaaacaatt tgagtaccta tgtccaaatt gtcatactat ttttgaacca
    15841 gactttaaag agtttgcctt ggcaggtcac acaccaagga cccgcaggct gacctgtcct
    15901 cattgccatc aaaaatctta ctgccttgaa ttggccaagg aaaaataatg gaaaatctcc
    15961 gctggatacc cagtggagat ttcttgctat tagaatggta gcttgccagc aaaggctcct
    16021 agagttttct tagtcgcctc atcaatttga gcgagggctg cattgatggc ctgagcagtc
    16081 atatcctgaa gtgtctctat atcctctggg tcaacgactg cttccttgaa atcaatgcta
    16141 accaattgct tatcacctgt aaaggttgca gtgaccagct cctgagctga ctttcctgta
    16201 aattgcatag ctgctaggtc agcctgcttt tgttccattt gcttttgaag cttttgcgct
    16261 tgcttcatca tgttttgcat gttcatcata agttccaatt ctcctaagtt ttgatactta
    16321 actattataa catatcagac aagacttcaa acatgtgatc ttttaaagtt aatgaaaagg
    16381 ccctgctagc ctgcaatgct ttgatgtgct agcgactaac gaacaggtcg tttcctttaa
    16441 atagagtttt cttgttgagc tttatagctg gtgcttgttt ttgtgatgag cttgtgtgag
    16501 gctgtcgtta gtgttgtttt aggtggtttg acatcaggag cgattaaaaa agttatcagt
    16561 ttacattttt ataataataa cttaagaatt aatttaactt tagattaatc ttactttata
    16621 tttgattgct atacttagtc cataacataa ataaccaaaa agaaagaggt aatcgttatg
    16681 acaacaatga ctacaacaaa acaatcaaag acaactctag cagctcgtta tttgaagctt
    16741 ggtcttactt cagcaatgtt tgctggagga gcctttctag ctctaggctc agcaccggct
    16801 gtctctgctt ctacccatgc tggtaatgat cagccagcga ctcaacgctt aactgatcag
    16861 gagatctacg aacgtgctca aaagctagac ttgccagact atgtgagagg ctcaatctac
    16921 ggtattctca accaaaactc aagtgttact tatccaaagg atatagcagg tctagagcag
    16981 tcagaagctc cacaaccccc tgcagctcca cagctcactg accaagatgc tcaaaagctg
    17041 gacttgccag actatgtgag aggctcaatc tacggtattc tcaaccaaaa ttcaagtgtt
    17101 acttatccaa aggatatagc cggtttagag cagtcagagg ctccacaacc ccctgcagct
    17161 ccacagctca ctgaccaaga tgctcaacag ctagacttgc cagactatgt gagaggctca
    17221 atctacggta ttctcaatca aaactcaagc attacttatc cgcgcgatta ttaagcatct
    17281 aagatgatta aggtgcacaa tcgacgatta aaatgattga tgagttaatg agattagaat
    17341 tatttggcta agttaagaat tagtgttata cttgagagag tgtagcacta attttttaat
    17401 caaggaggaa gcatgaccta caagatatta ttggtggatg atgaattgga aattattgat
    17461 attaacgaac gttatttgca acaggcaggg tatcgtgtta ccactgcaag cgatggtagt
    17521 caagccttgg agctttttca taaggatcag tacgatttga ttatcagtga tgttatgatg
    17581 cccaatatgg atggctatga ttttattggg gaggttttac tggaaaagcc agatcagccc
    17641 tttctcttta tcactgcaaa aacatctgag cctgacaaga tttattcctt gagcttggga
    17701 gcagatgatt ttatttccaa gccctttagt ccacgtgaat tagtcttacg ggtcaaaaat
    17761 attttgaatc ggatttatgg taaggctaac caagctgact ccttagttat tggggatttg
    17821 gtcatggatc acagcactcg aagggttaca gtggcaaatc aagatctgaa tctgaccaac
    17881 aaggcttttg atttgttgtg gattttggcc aatcatttga atcatgtctt ttcaaaaaca
    17941 gagctttatg agcgt
//
LOCUS       DARYXS010000037        17668 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.038, whole genome shotgun sequence.
ACCESSION   DARYXS010000037 DARYXS010000000
VERSION     DARYXS010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17668
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.038"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..1230
                     /locus_tag="TV193_001027"
     CDS             <1..1230
                     /locus_tag="TV193_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1513230.1"
                     /translation="FNKHIYDKLYDYDTFTEVHYGGASSGKSHGVIQKVVLKACQDWK
                     HPRKVLFLRKVGATVYDSIFEDVKQCLELWGLLDKCKVNNSAYRIELPNGATFIFKGL
                     DNPEKIKSIKGVSDVVMEEASEFTLDDYTQLTLRLRDRKHLKKQIFLMFNPVSKVNWV
                     YKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELANRNEAYYKIYALGQFATLDKL
                     IFPKYEKKILNKDKLSHLPSFFGLDYGFINDPSAFLHVKIDDNNKKLYILEEYVRKNL
                     TNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIPRIIDVKKGPGSVMQGIQYLL
                     QYDWIVDERCVKTIEELENYTWKKDKKTNEYINDPVDSYNHCIDAIRYATSNHFLTLD
                     KKQSNSFNIFRKAGFGL"
     gene            1242..2744
                     /locus_tag="TV193_001028"
     CDS             1242..2744
                     /locus_tag="TV193_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1513231.1"
                     /translation="MLYTETFKDSTGNAKLLEFRFHRESRMRYQTSDLSGLFDEGYKL
                     LLDYIKHHESKQKPRIQELLDYAEGNNHTVCESGRRREADMADSRAIHNYGKYISTFK
                     QGYLVGNPIRVEYEDNDDAKKQLFKELADKNNFHQLNRRLVKDLSKVGRAYELIYRSM
                     DDKTEVVRLDPRETFIIYQADVGQASLVGVRYYNKSQLDRTKKTVEVYTDNEIIYFDY
                     DGQLTEVDRRPHIFKSVPITEYLNTDDGLGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPSYVDTKEKAIEYLRAMRKARLLNLEPPVDTEGREGSVDAKYLYKQY
                     DVNGTEAYKDRVVQDIHRFTNTPDMSDSKFAGTQSGEALKWKVFGLDQERVDLQALFE
                     QSLKRRYKLIARVSELLKEIDGFDISKLKITFTPNLPKSLHEKIEAFKALGGELSQKT
                     TMSITDIVENPDKEIASINDEAKNRSLLAQKMESEGRMTDRELARDYNHE"
     gene            2725..4302
                     /locus_tag="TV193_001029"
     CDS             2725..4302
                     /locus_tag="TV193_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL1513232.1"
                     /translation="MTTIMNKSKYWRDRVKKEMDAKEADDISLEQSMKQLHNYHFRNI
                     EKEIESFYQRYADKEKIDIAEARKRVSELDISAYQKKAKELVVKAEKLRKEGKTVTRD
                     DFTHQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKTFLDEGYRKEVEF
                     QAGLLGLSVASQASVKGLADAVINANFKGAKWSDSIWDRQDKLRSIISQSVQSAILKG
                     KNGLTIARDIRREFDVSVSYAKRIAITEHARVQMEVSRLSMAENGFAMFDIIPEPKAC
                     DVCKDIAKQGPYHMDKWRTGENTPPIHPYCRCAVVGVEEENSSNHESLDKLIKTEYNQ
                     SMKESSTYARNVLSAVSLIEPRITSQIKHIVKQSNGNLQGLDFRLKSLDSLARKISTD
                     SLLDDISPEEAANNINDALRYTAVFKPDNFFDDYHSMKNALVRDGFKIEKVKNTWLDD
                     GPYNGVNTVVSKDNVKFEIQYHTQESFDLKNGKLHELYEERRLPNITRKRKAELDKMM
                     FELSKSLTKPNQIERVN"
     gene            4304..4510
                     /locus_tag="TV193_001030"
     CDS             4304..4510
                     /locus_tag="TV193_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513233.1"
                     /translation="MITKYFFIKTEHPKIVRYSNGLTEVYNSAKGWEEQEAWYDRLFF
                     SDFSDFEEVTEKEAKMFIAGLTAA"
     gene            4507..4926
                     /locus_tag="TV193_001031"
     CDS             4507..4926
                     /locus_tag="TV193_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1513234.1"
                     /translation="MSIVELAFRVAKKAHLGQVDKAGVDYIKHPITVASFVKTDEEKA
                     TAYLHDVIEDTSLTLLDLEEYDFPRSVIEAVDILTKKKGQDYQSYLNLVKTNKLARTV
                     KLADLKHNSDLSRLSEVTNKDLKRYKKYQEAIKYLNN"
     gene            5123..5392
                     /locus_tag="TV193_001032"
     CDS             5123..5392
                     /locus_tag="TV193_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513235.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENALQAEALINQNKEIMELKSIVE
                     RNALATNEELATVKDTVLDNQSVIKAIGDTVDYIKQNYKRKWGKK"
     gene            5428..5595
                     /locus_tag="TV193_001033"
     CDS             5428..5595
                     /locus_tag="TV193_001033"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513236.1"
                     /translation="MKVKEIAQVFNEYSDFFVVQNGKYLPGDRTSFFLDCELEIKEIS
                     IGIPDCLIIEV"
     gene            5777..6400
                     /locus_tag="TV193_001034"
     CDS             5777..6400
                     /locus_tag="TV193_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1513237.1"
                     /translation="MNKKLLEKLFKCAPDTGTGSGGASDADSQQSETDGEPSSEDSFK
                     APQSQSELDSYTNKAIQKALENQRKDEAKRIEEAVKAALDKEKDYSKLSEEERQQREF
                     EDSKKAFEAEKAKFEHDKLVVQVEKDLIAKGLPSEFAELLATKDAENALEQVKTFEAA
                     FKKAVADEVKKTVRQLTPSTGAGAISTQTNYGANLASKIAQQSTTLF"
     gene            6411..6791
                     /locus_tag="TV193_001035"
     CDS             6411..6791
                     /locus_tag="TV193_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEL1513238.1"
                     /translation="MNKRKVTTSKEILHNLEYEAITVTLDSSTVGKKVIPAGTVLAGV
                     SDSVFKDRKQKVKTVANHEVSGESNICGILLTDVDLTDGDKAGACVYRGTVNADKLAD
                     SSIAENFTELATKLPHVVFIKGGK"
     gene            6794..7843
                     /locus_tag="TV193_001036"
     CDS             6794..7843
                     /locus_tag="TV193_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEL1513239.1"
                     /translation="MALIHEIITSENIKGFYNAKNENIDKTLGEKAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLDEEMPYFKEAMLVKEADRQELNIISQ
                     TKNSDLIDTVLAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPSVKWSEAETATPLKDIEGAIEKMAERGFVPEAIIMNSKTFSLIKNAKSTLK
                     IIKPMAPDGAAVTKGDLTTYIADELGLKILFKDGMFIGDDGKSRKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLMGGHATDADVSLVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIIDSIDQV"
     gene            7854..8120
                     /locus_tag="TV193_001037"
     CDS             7854..8120
                     /locus_tag="TV193_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513240.1"
                     /translation="MAEVIKTFRDKETTNTYYVGDDYNGDRIDELTAKGYLSGDKVSA
                     AAIEIDLDKLKVDEIRAKLDELGVAHDPKLKKPELLELLKQSAS"
     gene            8130..8483
                     /locus_tag="TV193_001038"
     CDS             8130..8483
                     /locus_tag="TV193_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1513241.1"
                     /translation="MQKINTDSIIANVKLDLGIDDTLQDSLLNMLLKRVTDHFKAEYG
                     VDDIDNAFSFVLEDCLIARFNRRGSERAKSEEVEGHKTTYYDFLNEFEPYDKMIKSNL
                     NLIKDNSRKGGLYFL"
     gene            8480..8788
                     /locus_tag="TV193_001039"
     CDS             8480..8788
                     /locus_tag="TV193_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513242.1"
                     /translation="MRYADRITFVKATDEQYDPDLGEYTYTEVMIKTLPCFVMDLGMA
                     KSVQIFGDYQKTRKVVYLRQPYTDLLDHCLYKGKKYKVQVDKQFNTVFYLEGDDSICS
                     "
     gene            8769..9134
                     /locus_tag="TV193_001040"
     CDS             8769..9134
                     /locus_tag="TV193_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1513243.1"
                     /translation="MILFVADISLKVVGTTGLKNKLELIAKKEAVKKIVRDNGKQLHR
                     KMVQKAVFTKGHSTGATRISITMQIGDDGFSVTVKPGTHYAGYLEKGTRFMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            9131..9520
                     /locus_tag="TV193_001041"
     CDS             9131..9520
                     /locus_tag="TV193_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1513244.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVDLVLSVWGLQKKRKQVSDMASAIFSQAMSVASSDSFYWSLNIRQ
                     SSIQVLDDTTTVTPLKRAIVTLRFNLR"
     gene            9530..10121
                     /locus_tag="TV193_001042"
                     /pseudo
     CDS             9530..10121
                     /locus_tag="TV193_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
     gene            10183..10542
                     /locus_tag="TV193_001043"
     CDS             10183..10542
                     /locus_tag="TV193_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEL1513245.1"
                     /translation="MQLEIKGKTHNIKFGTRFVAEMDKNHIAEREGMKFGAGLQSTVP
                     FLFERNVVTLAEIIYTGTITESPRPSLNDIYDYIDEAEDIEKLFDDVLDELRQSNASK
                     LFITKLDKNIAEMATEA"
     gene            10584..10913
                     /locus_tag="TV193_001044"
     CDS             10584..10913
                     /locus_tag="TV193_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513246.1"
                     /translation="MIVLNCVRYLGMTDINEIGRLTLYEYDLLMIGKALASVDEAYKA
                     HKQAWINHQVSATRLVGGGKNKREVPVYKTFKEFFDYETEIKKITNEIDESYDKKAMD
                     LLLKANL"
     gene            10930..14184
                     /locus_tag="TV193_001045"
     CDS             10930..14184
                     /locus_tag="TV193_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1513247.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLKSAVQSIEGLEKRSKGFSAVSQ
                     KAGSMFKSMLGANLAGQAITALGRTVSSGLISMIGEMNSSAKAWKTFDANLADIGFGK
                     QQILEAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKAMGKNLNELVADIQAGRVK
                     TKDFLEAVKQAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKINFSKFAAGLGKFLEGVNIDSIISRISTSISSIVSKIKGFWDGFNQTGAI
                     SAFSGALQSVWGALKNTAKAMSGGSWKTFGSIIGEIVKHVSNFARVIGDVVGKMDPSR
                     LKSWIATLAAVGGGLKIFEKLTGQSVIGSFLDKIGSKFKIFGNKAKEGTEQAFNGVKR
                     SGGIISKIFNGLGNIVKSAGTAIATAAKGIATGFSIAFKGLGSAISMVPPATWLALGA
                     AILAVGAAFALAGTQADGISQIFKTVGDVVVQVLQQVTNSLATLIPIIVSAIGSILPI
                     VAGAISQVVAAVAGGLSQIITAVANGVSTIIGAFTGLLGGVSSVITSISGVIQSLAGV
                     ITSVFNGIATIISSVGSAIKDVLTGLGSAFKGFGNGVKSALEGVGTVIKSFGSAVRNV
                     LDGVAHIFDSMGNAALNAGRGVKEMAKGIKMLVDLSLADLVATLGAVATGLGNMAGSA
                     GQMTTLSSAMSEVANGMARLGTSATIAITGLTVFATTITTIQTAIATLPTILTAAASG
                     FREIGDSATAAVGRIQTFAAGTTVVASAFASMQSMIRSAMAAIVSSIITSFNQAASQI
                     QSILSRVLSQARTFGSQLEQQMRQSGQRSGQNLAQGLSSQQGAVINAVSSMVNAAVSR
                     ANAGASPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARAKAMIHSPSRLF
                     AKRVGQYIPQGVAMGIYKNADVVDDSVGELFDSINSFDFNIADRLTSIGARFQGVVKS
                     ESSQSLSQQQEFVHTAQPAYVNFSLGGNEYEAFVSDITNRQAKIEKIRLKRSSW"
     gene            14216..14995
                     /locus_tag="TV193_001046"
     CDS             14216..14995
                     /locus_tag="TV193_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1513248.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDMVDLEHQTTSVLGRDGEYFHNATVEVRKLEIKAKITGKDNRSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDIPEEVSNEQIIGLVFICYDPFKMSDIKTKKGNT
                     VQNDGLFNTKPIITLNLSSSTKEIRLLHVESQKYIRLTGTYTTDEIKIDMTTGKITQN
                     GRNILSDLDMVNSRYFDLLPGKNTLQCDNATITADFREVYL"
     gene            14992..17049
                     /locus_tag="TV193_001047"
     CDS             14992..17049
                     /locus_tag="TV193_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1513249.1"
                     /translation="MIYLFDKLEQLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     IEPFVYFGFFNYDPSQKEDVFKLFKVIDYNLEDSKYYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGISEIRTLSYYYISPRAAMIKMIEAFNCEFNVRY
                     TFVNNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     YDEPEAKEVEGHLPEAEKRQGYGRRIEFSDVVWSVEKGDSIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKAELLKATWDQLQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNREARSRKEAVQNMI
                     NDSIENITGLGMNLQEFFQGIEEKIATGKKEMEDNWRKVNLEFDNFKKLIEQEGRNFR
                     ERLEAETKELDERNQKELDEFRETLKNLSLPEEAIKKITEAIKVDDIPSLKQSFDELK
                     NEVSKNSEKSRLNAEIIGTNGKTRYNKNLLVGEPNRTKTYDQDFVEIEANDGGFRRGE
                     TYTISFSQTCELLKKVAITLTQPHNKGLKLVLTPTKAKMEAQTFDLTKDIEVISVYPL
                     SYRAVLTGDWYKSKQMDFNAAEVQDLALEMSYRDVVDSNNASLILDWSSNPDVIFDGN
                     GGS"
     gene            17049..>17668
                     /locus_tag="TV193_001048"
     CDS             17049..>17668
                     /locus_tag="TV193_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1513250.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGAQGPQGPAGETGPQGPPGPTGQRGETGPQGPPGPQGPPGADG
                     KMTFEQLTPEQKQQLKGAGIQSISLDYEGYLTIQLDNGQSFRSDISLKGPQGEPGING
                     MDGPRGATGPQGPAGDPASIPDDVVRRGELAAYLLKSEYKAKGAGSG"
BASE COUNT         6001 a         3027 c         3941 g         4699 t
ORIGIN      
        1 tttaataagc atatttatga taaattatat gactatgaca cttttacaga ggtccattac
       61 ggcggagcat cgtctggtaa atctcatgga gttattcaaa aagtagtatt aaaagcatgc
      121 caagactgga agcaccctag aaaggtgctt tttttacgca aagttggtgc aactgtttat
      181 gactcaatat tcgaagatgt gaaacagtgt cttgagttat ggggtctact agacaagtgt
      241 aaggttaata attcagcata taggattgag ctgccaaatg gggcgacatt tatttttaaa
      301 ggcctagaca accctgagaa aatcaagtca attaaaggcg tgtcagatgt cgttatggaa
      361 gaggctagcg agtttacgct tgatgattat actcagctaa ctcttcgtct gcgtgatcgt
      421 aaacatttaa agaaacaaat ttttttaatg tttaacccgg tatcaaaagt aaactgggtt
      481 tataaagcct tcttcgttaa gacacctaag aatacagttg tctatcaaac aacttataaa
      541 gacaaccgtt tcttagatga tgtcacgaga gaaaatatcg aggaactagc caataggaat
      601 gaagcttatt acaaaatata tgcccttggc cagtttgcga cattagataa gcttatcttc
      661 ccaaaatacg aaaagaaaat attaaataaa gacaaattat cacacttgcc ttcttttttt
      721 ggcttggact atggatttat taatgatcca tcggcatttt tgcatgtcaa aattgatgat
      781 aacaataaaa aactttacat cttagaggag tatgtgagaa aaaatctaac aaatgataag
      841 atagcaaatg ctataaagga cctcggatat gccaaagaag agattagggg agactcagca
      901 gaaaagaaat caaatcaaga gcttagaaat ttaggtatcc caaggataat cgatgttaag
      961 aaaggtccgg ggtctgtcat gcaagggatt cagtatctgc tgcaatatga ctggatagtt
     1021 gatgaaagat gtgtcaagac cattgaagag ttagaaaatt atacctggaa aaaagataaa
     1081 aaaacaaatg agtatattaa cgacccagtc gatagttata accactgcat tgacgcgatt
     1141 aggtatgcga catctaatca tttcttgaca ctggacaaaa aacaatccaa tagctttaat
     1201 attttccgca aagcaggttt cggactctag aaaggagaac aatgttatac acagaaacgt
     1261 ttaaagacag cacaggtaat gctaaattac ttgagtttag attccatcgt gagtctcgta
     1321 tgaggtatca gacaagcgat ttaagcggcc tttttgacga agggtataaa ctattgcttg
     1381 actatatcaa acaccacgaa agcaagcaaa aaccacgcat acaggagctt ttagactatg
     1441 ctgagggtaa taatcataca gtctgcgaat caggccgcag acgagaggct gatatggcag
     1501 acagtcgtgc tatacacaac tacggtaagt atatctcgac ctttaagcag ggctatttag
     1561 ttggaaatcc tatccgcgtg gaatatgagg acaatgatga tgctaaaaaa caattgttca
     1621 aggagctggc ggataaaaat aacttccacc aacttaaccg tagacttgtc aaggatttat
     1681 ccaaggtagg ccgcgcctat gaacttatct atcgcagcat ggacgataag acagaggttg
     1741 tgcgattaga tccacgagaa acctttatta tctatcaagc tgatgttggg caagctagcc
     1801 ttgtgggtgt gaggtactat aacaagagtc agctggatag aacaaagaaa acagttgagg
     1861 tctacacaga taacgagatc atttactttg attatgatgg gcaactgaca gaggttgata
     1921 ggcggccaca catttttaaa tctgtaccta tcacagagta tctcaatacg gacgatggcc
     1981 ttggtgatta tgagacggag ttgtctttaa ttgacttgta tgatgcagct caatcagaca
     2041 cagcaaacta tatgcaagat ttgtcagatg caatcttggc tattattggt cgagtatcgt
     2101 tcccgagtta tgtagacacc aaggaaaaag ccattgaata tctgcgtgct atgcgcaaag
     2161 ctaggttgct aaatttagag ccaccagtgg ataccgaagg tagagaaggt tctgtagatg
     2221 ctaagtatct ctataagcaa tatgatgtca acggcacaga agcttataaa gatagggttg
     2281 tgcaagatat ccacagattt accaacacac cagatatgtc agatagcaaa tttgcaggca
     2341 cgcaatctgg agaggcactc aagtggaaag tctttgggct tgaccaagag cgtgtagact
     2401 tgcaagcact gtttgagcaa tctctaaaac gtagatataa gcttatcgca agagttagtg
     2461 agctgttaaa agaaattgac ggatttgaca ttagcaaact taaaattact tttaccccta
     2521 acttaccaaa atcgctacat gaaaaaattg aagcttttaa agcacttgga ggggagttgt
     2581 cgcaaaaaac aacaatgtct attacagata ttgtggaaaa tcctgataaa gagattgctt
     2641 ccatcaacga tgaggctaaa aatcgtagtt tattggcgca aaagatggag tcagaaggta
     2701 gaatgacgga tagggagtta gctcgtgact acaatcatga ataagagtaa atattggcgt
     2761 gatcgtgtta aaaaagaaat ggacgcaaaa gaggcagatg atatctccct tgaacagtcc
     2821 atgaaacaat tacacaatta tcattttaga aatatcgaaa aagaaattga gtcattttat
     2881 caacgttacg ctgataaaga gaaaatagac atcgcagaag cccgtaagag agtttctgag
     2941 cttgacattt ctgcttacca gaagaaagct aaggaacttg ttgtaaaggc tgagaagcta
     3001 cgaaaagagg gtaagacagt aacgagagat gactttaccc accaagaaaa tgcagacatg
     3061 gccatctaca atttagcgat gaaaactaac gctttagaat tgttgcgctt gaatatcgac
     3121 ttggagatgc aggagctcgc aaatggcgaa cataagctaa ccaagacatt tcttgacgaa
     3181 ggataccgca aagaggttga gttccaagcg ggattgttag gactgtcggt tgctagccaa
     3241 gcaagcgtga aagggttggc tgacgcagtt attaacgcta atttcaaagg cgcaaaatgg
     3301 tcggatagca tttgggacag acaagataaa ttacgcagca ttatatccca gagcgtacag
     3361 agtgctatct taaaaggtaa aaatggttta actattgcaa gggatattag acgagagttt
     3421 gatgtgtcag tgtcttatgc aaagcgaata gcaatcactg agcatgcaag ggtgcagatg
     3481 gaagttagta gattatccat ggcggagaat ggctttgcta tgtttgacat tatcccagag
     3541 cctaaagcat gtgatgtttg taaagacatt gctaaacaag gtccatatca catggataag
     3601 tggcgaacag gggaaaacac gccgcccatc catccttatt gcaggtgtgc agttgttgga
     3661 gtggaagaag aaaatagtag taatcatgaa tcacttgata agcttattaa aacagagtat
     3721 aatcaaagta tgaaagagtc atcgacttat gctcgtaacg ttttgtcggc agtgtcattg
     3781 atagagcctc gaattacatc gcaaattaag catattgtca agcaatccaa cggtaattta
     3841 caaggacttg attttagatt aaaaagtcta gattctttgg ccagaaagat ctctactgat
     3901 agcttgttgg acgatatttc accggaagaa gccgcaaaca acataaatga tgcattacgc
     3961 tatacagctg tatttaaacc agataatttt tttgatgatt atcatagcat gaaaaatgca
     4021 ttggtcagag atggttttaa aatcgaaaag gtgaaaaata cttggctaga tgatggtcca
     4081 tataacggtg ttaatactgt tgtatcaaaa gacaatgtca agtttgaaat tcaatatcat
     4141 acccaagaaa gctttgattt aaaaaacggg aaactgcatg aattatatga ggagagaaga
     4201 cttcctaata taacacgaaa acggaaggct gaactagaca aaatgatgtt tgagcttagt
     4261 aaatctttaa ctaaacctaa ccaaatagaa agggtgaatt gatatgatta caaaatattt
     4321 ttttataaaa accgaacacc ccaaaattgt tagatattct aatgggttaa cagaagttta
     4381 taacagcgca aaaggctggg aagaacaaga agcttggtac gatcgtctat tctttagcga
     4441 tttcagtgat tttgaagagg ttacagaaaa agaagctaaa atgtttattg cgggattgac
     4501 agcggcatga gtattgtgga gctagctttc agagtggcta aaaaagccca ccttggacag
     4561 gttgataagg ccggtgtcga ctatattaag caccctataa ctgttgcaag ttttgtaaaa
     4621 actgatgaag aaaaggcaac ggcttatctt catgatgtta tcgaagatac aagtttgact
     4681 ttacttgact tggaagagta tgattttcct cgaagtgtta tagaggcagt tgatatactg
     4741 acaaagaaaa aaggacagga ttatcaatcc tatctaaacc ttgttaaaac aaataaactt
     4801 gcaagaactg taaaattagc tgatttaaaa cacaattctg atttatctcg tctctctgaa
     4861 gtaactaaca aagatttaaa acgctataaa aaatatcaag aagctatcaa atatttaaac
     4921 aattaaacaa caacagacgg gcaaccgtct ttttttgtac cccaaaaaca ggaggaaatg
     4981 atgttgaaaa tagtgaaatt tttgaaatat gtttggattt ataagtgtaa acctgtcagt
     5041 ccaagtcttt atgcatcgag tcggattgag tacttcaaac ctcttggtta ttactgggaa
     5101 aaagcaacga taggagaaag caatgaataa acgaatcaaa aagaaacgta aactagaaac
     5161 agtagtagtg atgctggttg cggaaaatgc cttgcaggct gaagcgctca taaatcaaaa
     5221 caaagaaatc atggagctaa aatcaatcgt tgagcgaaac gctctggcaa caaacgaaga
     5281 gttagcgact gttaaagaca ccgttttaga caaccaatca gttatcaagg caattggtga
     5341 cacggttgac tacatcaagc aaaattacaa acgtaagtgg gggaagaaat gaagtatctc
     5401 aagaaaaagt aatagtaagg agttattttg aaagtcaaag agatagcaca ggtgtttaat
     5461 gaatattcgg atttttttgt ggtacaaaac ggtaaatatc tacctggtga cagaactagt
     5521 ttttttctag attgcgaatt ggaaatcaaa gaaatatcta tcggaattcc tgattgctta
     5581 attattgaag tataaaaaat tcaaagtcgt agcaatacgg ctttttattg tgccctgagc
     5641 atggcctaaa aaggctcaaa ttaatcacta gcgtggcttg tggataaata cacctaatag
     5701 agactagaaa acatgaggcg cccgttttcg tggctctgca gtgtgtttaa aagcaagact
     5761 agcgtgggag gaaaaaatga ataaaaaact attagaaaaa ctttttaaat gtgctccaga
     5821 tactggcaca ggttcaggag gagcttctga tgcagatagc caacaatccg aaacagatgg
     5881 agaaccatct agtgaagaca gctttaaagc tccacagtcg caatcagagt tagatagcta
     5941 tacgaataaa gcaatccaaa aggcattgga aaatcaacgc aaagatgaag ctaaacgaat
     6001 agaagaagct gtaaaagctg ctttagataa agaaaaagac tactccaagc tatctgaaga
     6061 agaacgtcag cagcgtgaat ttgaagatag taagaaagcc tttgaagctg aaaaagccaa
     6121 gtttgaacac gataaacttg tagtccaagt cgaaaaggat cttatcgcaa agggattgcc
     6181 ttctgagttt gctgaattgc ttgctacaaa agatgcagaa aatgcgctag agcaagtcaa
     6241 aacattcgaa gcagcattta aaaaagcagt agctgatgaa gttaaaaaga ccgtacgaca
     6301 acttactcca tcaactgggg caggtgcaat atcaacacaa acaaactatg gggcgaactt
     6361 ggcgagtaag atcgcacaac aaagcaccac attattttag gaggaaaaaa atgaataaac
     6421 gtaaagtaac aacatcaaaa gagattctcc acaatctcga atacgaagct attacagtca
     6481 ctttagattc aagcacagtt ggcaaaaaag ttattccagc cggtacagtt ttggccggtg
     6541 tatcggattc tgtttttaaa gatcgcaaac aaaaagtaaa aactgtggca aatcacgagg
     6601 tcagcggaga gagcaatatt tgtggaattt tgttaaccga tgttgatttg acagatggtg
     6661 ataaagcagg tgcttgtgtt tatcgcggta ctgtcaacgc agataaactt gctgattcat
     6721 caattgcaga aaattttacg gaattggcga caaaactacc acatgttgtc tttattaagg
     6781 gaggtaagta agcatggcat tgatccacga aattatcaca tcggaaaaca tcaaaggttt
     6841 ttataatgct aaaaatgaga acattgataa aacgttaggg gaaaaagcat tcccaccaaa
     6901 acagcaatta gggcttaagc tatcctttat caagggtgcg gcaggaaaac ctgtgacact
     6961 taaagcggcc gcttttgata ctaaagtacc tctacgtgac cgcatggcag ttgagctgct
     7021 tgacgaagaa atgccttact ttaaagaggc tatgcttgtt aaagaggcag accgtcaaga
     7081 gcttaacatt atatctcaaa caaaaaatag tgatcttatt gacacagttt tagcggcaat
     7141 ttataacgat aaggtaacgc ttatcgcagg cgctaaagca cgtttagaag caatgcgtat
     7201 ggaagtgctg tctaaaggta aaatccacgt cgcatcaaac ggtgtcatga aagactttga
     7261 ttatggacta gactcttcgc aaacaactaa gccaagtgtt aaatggtctg aggcagagac
     7321 cgcgacacca cttaaagaca ttgaaggtgc aattgaaaaa atggcagaac gtggctttgt
     7381 gccagaagca attatcatga actctaagac atttagtttg attaaaaacg ctaaatcaac
     7441 tcttaaaatc atcaaaccaa tggcaccaga tggggcagct gttaccaaag gtgatttgac
     7501 gacttatatt gctgatgaac taggactcaa aattttgttt aaagatggta tgttcattgg
     7561 tgacgatggc aaatctcgta agtatttccc agatggcttt gcaactttgg tacctaacgg
     7621 caaccttggc tacactgtgt ttggcactac tccagagcaa tcagatctca tgggtgggca
     7681 cgcaacagat gcagatgtgt cgttggttga gactggtatt gcaatcacaa ctactaagac
     7741 aactgatcca gtaaatgttc aaaccaaggt atctatgatt gctttgccgt cattcgaacg
     7801 attggaagaa gtgcaaatta tcgactccat tgaccaagta taaggagggg gttatggctg
     7861 aagttattaa aacttttagg gataaagaaa ccactaacac ttactacgta ggagacgatt
     7921 acaacggaga ccgcattgat gagttgacag ctaaaggata cctatctggt gataaggttt
     7981 ctgctgccgc tatagagatt gaccttgaca aattaaaggt tgacgaaatt agagcaaaac
     8041 ttgatgagtt aggcgtcgct catgacccta aactaaaaaa gccagaatta ttagaacttt
     8101 tgaaacagtc agctagctag gaggtgttta tgcaaaagat aaacacagat agcattatag
     8161 ctaacgtaaa actcgattta ggtattgatg acaccttgca agacagtttg ctcaatatgt
     8221 tgctaaaacg tgttacagac cattttaaag cggaatacgg cgttgatgat atagacaacg
     8281 ccttttcgtt tgttttggaa gactgtctaa ttgctaggtt taatcgcaga gggtcagaga
     8341 gggctaagtc ggaagaggta gagggtcata aaacaaccta ctatgacttt ttaaatgagt
     8401 ttgagcctta cgacaaaatg attaagtcca accttaattt gattaaggat aattctcgta
     8461 aagggggatt gtacttttta tgagatatgc agataggatt acgtttgtta aggcgacaga
     8521 tgaacaatat gaccctgatt taggtgagta cacatatacc gaagtcatga tcaagacatt
     8581 gccttgtttt gtcatggact taggtatggc taaatctgtg cagattttcg gagactatca
     8641 aaaaacacga aaagttgttt atttgcgcca accttatacc gatttgttag atcactgtct
     8701 ctacaaaggc aaaaagtaca aggtacaggt ggataagcaa tttaatactg ttttttatct
     8761 ggagggagat gattctattt gtagctgata tatctttaaa agtagttgga acgacagggc
     8821 taaagaataa acttgaactt attgccaaaa aagaggctgt caagaagatt gttagagata
     8881 atggaaaaca actacacagg aaaatggtcc aaaaggcagt atttaccaaa ggtcattcca
     8941 ctggtgctac cagaatatcc atcacaatgc agattggtga tgatggtttt agtgttacag
     9001 taaaacctgg cacgcattat gcaggttatt tagaaaaagg cactcgcttt atgagtaagc
     9061 aaccttttgt gttgccagct ctaaaagagc aaaaagtaaa attcagaaaa gatttggagg
     9121 cgcttgtcaa atgattaaaa ctagagatca atctattttt gacgagatgt ttaagcgtat
     9181 tcagtcttta ggttttaaag tttatgatta caaaccgatg actgaggttc cttatccgtt
     9241 tgtggaaatg gaatctactg atgcagaata tattccaaat aaagatgaca ttaaaggctc
     9301 tgttgacctc gtactgtctg tttggggatt gcaaaaaaaa cgaaagcagg tgtctgatat
     9361 ggcatctgct attttttcac aagctatgtc agtggctagt tctgacagct tttactggtc
     9421 gttaaatatt cgtcaatcat ctatccaagt gttagatgac acaacaacag tgacacctct
     9481 caagagagcg attgtcacat taagatttaa tttaagatag gaggtcgcaa tgccaggacc
     9541 aagtagatta ggatccaaag atgaagacca ctccacacaa gaaaggaagg aaaaaatggc
     9601 agcgcaagat caagtacaat tagaagcaaa acaagggatt catgcaatcc tattattccg
     9661 tttgttaaaa gaagcatcat cagaaaaagc agctaaactc gcttttcaaa cggaacacga
     9721 agttggtaaa agtcgtgatg tcgacggtca aaagactaaa gatggtatta tccagtctgt
     9781 cggagcttta gaatacgact ttaaagcaac atctatttta gccaaaggtg acaagttagc
     9841 agcaaaacta gaagaagcca tggaaaaagg tgagcttgtt gaaatttggg atattgattc
     9901 cgaaaaagca agtgaagaag cttgatagca aaggtaaata tccagctacc tattaccaag
     9961 gttacatttc aagtttcggc gctaagaaaa atgcagaaga aaatattgaa attgaaatgg
    10021 aatttgccat taatggcgtt ggtcaaaaag gatttgcaac attgaccgaa gaacaaaaag
    10081 cagctgtaca gtacaaattt aaagatacaa cagcaggtta atcaacaagg ccagttaatt
    10141 actggtcttt tatttttaaa tttttaaagg gggaaaagaa taatgcaatt ggaaattaaa
    10201 ggtaaaactc ataacatcaa atttggcaca cgatttgttg ctgaaatgga taagaatcac
    10261 attgcagaac gtgaagggat gaagtttggc gctggtttgc aatcaactgt tccgtttttg
    10321 tttgagcgta acgttgtgac acttgctgag attatctata cagggacaat cacagagtca
    10381 ccacgaccaa gcttaaatga tatttacgac tacatcgatg aggctgaaga tattgagaag
    10441 cttttcgatg atgttttaga tgagttgcgc caatctaacg cgtcaaagtt gtttatcacc
    10501 aaactggaca aaaacatagc ggagatggca accgaagctt aaagagttca accaaaaatt
    10561 attcttcaca agaaagcttt gagatgattg tccttaattg tgttagatat cttggcatga
    10621 ctgacattaa tgagattggt cggttgactt tgtatgaata tgatttattg atgataggta
    10681 aagcgctagc ctctgtagac gaggcatata aagctcacaa gcaagcttgg ataaatcacc
    10741 aggtctcagc tacgaggctg gtcggtggtg gtaaaaacaa aagagaagtt cctgtttata
    10801 aaacattcaa ggaatttttt gattatgaaa cagaaatcaa gaagataacc aatgaaattg
    10861 atgaaagcta tgacaagaaa gcaatggatt tacttttaaa agccaacctt taaatagaaa
    10921 ggaagttaaa tgggagaatc ttattcagtt gaagcggtgt tgacagcggt tgataaaacc
    10981 tttggtaaga ctttaaaatc agcagttcaa tcaattgaag gactagaaaa gcgttcaaaa
    11041 ggcttctcgg cggtgtctca aaaggctggg tctatgttta aaagcatgct tggagctaac
    11101 ttagcaggtc aagctattac agcgctagga cgtacagttt catctggact tatttcgatg
    11161 atcggcgaaa tgaatagctc agcaaaagcg tggaaaactt tcgatgccaa tttagcagat
    11221 atcggatttg gcaaacagca aattcttgaa gctaaaacag ctatgcaaga ttacgctact
    11281 aaaacaatct actcagcatc agatatggcc agcacatatg cacagttagc tgctgttggg
    11341 gtaaaggata ctgggaaact cgtaaaagct tttggtggtt tggctgcatc tgctgaaaat
    11401 ccaaaacaag ctatgaagtc aatcagtcag cagatgacac aagctgtggg aagacctaca
    11461 gtagcgtggc aagatttcag aataatgctc gagcaagctc cagctggtat ggctaaagtg
    11521 gccaaagcta tgggcaaaaa ccttaatgaa cttgtagccg acattcaggc tggtagagta
    11581 aaaactaaag acttcctaga agcagtaaaa caagctggta acgacaaaag cttccagaag
    11641 atggcgactg aattcaaaac tgtggaccaa gccattgatg gcatgcgtga aggtttatcc
    11701 aataaattgc aaccagcttt tgaaaaagtg aaccaatttg gaattagagc gattgaagca
    11761 atcgggaaac aactcgataa aatcaatttt tccaaatttg ctgcaggcct tggtaaattt
    11821 ctcgagggcg tgaacattga tagtattatt tcaagaatat caacatcaat ttcatctatc
    11881 gtttctaaaa taaaaggatt ctgggacgga tttaatcaaa ctggagcaat cagcgctttt
    11941 tccggtgctt tacaaagtgt ttggggagcg ttaaaaaata ctgctaaagc catgagtgga
    12001 ggaagctgga agaccttcgg gtcaatcatt ggcgaaattg ttaaacatgt ttctaatttc
    12061 gcaagagtga ttggagatgt cgttggcaag atggatccga gtagactaaa aagctggata
    12121 gctactcttg cagctgttgg tggtggattg aaaatctttg agaaattaac aggtcaaagt
    12181 gttattggat cttttttaga caaaatcggc tcaaaattca aaatatttgg aaataaagcc
    12241 aaagaaggga cagaacaagc ctttaacgga gtcaaaagaa gtggtggcat tatcagtaaa
    12301 atctttaacg gtttgggtaa tatcgttaag tctgccggta cagcgatagc gactgctgca
    12361 aaaggtatcg caactggttt ttctatcgcg tttaaggggc ttgggtctgc catttctatg
    12421 gtaccgccag ctacatggct agctttagga gcagctattt tagcggtagg agcggctttt
    12481 gccttggcag gaactcaagc tgatggcatt agtcaaattt ttaaaactgt tggcgatgtc
    12541 gttgtacaag ttttacaaca ggtcactaac agtctagcta ctctaattcc tattattgta
    12601 agcgctattg gctccatatt accaattgta gcaggggcta tttctcaagt cgtcgcagca
    12661 gttgctggcg gattatctca gattattaca gctgttgcta atggtgtatc aactattatt
    12721 ggggctttca caggtctact tggtggtgtt tctagcgtca ttacctcaat tagtggtgtt
    12781 atccaatcgc tggcaggtgt aattacctca gtatttaatg gcatagcaac cattatttcg
    12841 tctgtagggt ctgcaattaa agatgtatta acgggtctcg gcagtgcttt taaaggattc
    12901 ggcaacggtg taaaatcagc cttagaaggc gttgggacag taatcaaatc atttggtagt
    12961 gcagtcagaa atgtccttga tggtgttgcg catattttcg attctatggg taatgcagct
    13021 cttaatgctg gtcgtggcgt caaagaaatg gctaaaggca tcaagatgct tgtagattta
    13081 tcgcttgctg atttagtcgc aacgcttgga gcagtcgcga caggtcttgg gaatatggct
    13141 ggctctgccg gtcagatgac tacgttaagt tctgccatga gcgaagtagc caatggtatg
    13201 gcgcgtctag gaacaagcgc tacgatagca attactggat taacagtttt tgctactact
    13261 ataacaacta ttcagaccgc aattgcaact ctaccaacaa tcctaactgc agccgctagt
    13321 ggttttaggg agatcgggga ttcggcaact gcagcagttg gtcgaatcca gacttttgca
    13381 gctggtacaa ctgttgttgc atcagcgttt gctagtatgc aatctatgat tcgatctgcc
    13441 atggctgcaa tagtaagcag cattataaca tcatttaacc aagctgcctc tcaaatacaa
    13501 tcaattttat ctcgggtgct atctcaagct aggacatttg gatctcaact agagcaacaa
    13561 atgaggcaat cgggacagcg ttcaggacaa aatcttgctc aggggttgtc ttctcaacaa
    13621 ggtgctgtta ttaatgctgt ttctagcatg gttaatgccg cggtatcaag agcaaatgca
    13681 ggtgctagtc ctatgcgtca agctggagcg tacatcggac aagggcttgc gcaaggtatg
    13741 tattcagcgc taggagctgt aacagcagca gcaaacgctc ttgtagcaca agctgagagg
    13801 gcagcaagag ctaaggcgat gattcactcg ccatctaggt tatttgcaaa acgagttggt
    13861 caatatatcc ctcaaggggt agccatgggg atatataaaa acgctgatgt cgttgatgat
    13921 tctgtaggtg agctatttga tagtatcaat agctttgatt ttaatattgc ggatagattg
    13981 acaagtattg gcgctagatt ccaaggtgtt gtcaaatcag aaagttcgca atcgttgtcg
    14041 cagcaacaag agtttgtaca tacagctcaa ccagcgtatg taaactttag tttaggcgga
    14101 aacgaatacg aagcatttgt aagtgacatc actaatcgac aagcaaaaat tgaaaaaatc
    14161 agactaaaga gaagcagctg gtagttgttt ctcttagttt tatgaaagga gtaaaatgta
    14221 cgaatttaac gatactatca gagggactcc gaaagttact ttcaatttaa aaacaacaat
    14281 tggcgaaaag gtattagaag aagagctcaa taatgattta ggtaccttta ggacattgac
    14341 cgtttctggt cgtgatatgg tggacttaga acaccagaca acaagtgttt tagggcgaga
    14401 tggcgagtat ttccacaatg ccacagttga agtcagaaaa ctagaaataa aagctaaaat
    14461 tactggaaaa gataaccggt caatgcgttt gcaatatgaa aaattaaaca gattaattgt
    14521 tagtcataat caagtttttt tatcattttc agacgagccg gacagaaatt atctaggcat
    14581 ctttaaatct aaagatatac cagaagaagt ttctaacgaa caaatcattg gcttggtttt
    14641 catctgttat gatccattta aaatgtcaga tataaaaacc aaaaaaggta atactgttca
    14701 aaatgatggc ctatttaata caaaacctat cataactctc aacctctcat catcaacaaa
    14761 agaaattagg ctgctacacg tcgaaagtca aaagtatatc agattaactg gtacttatac
    14821 tactgacgaa atcaagattg atatgacaac aggtaagatt acccagaacg gccgtaatat
    14881 tcttagtgat ttagacatgg ttaacagtcg ctattttgat ctattacctg gtaaaaacac
    14941 tttgcagtgt gataatgcaa cgattacagc tgatttcagg gaggtttatc tatgatttat
    15001 ctctttgata agctggagca attagttgct actgttggta ctgatgactt gctctcatgg
    15061 cattttaagg tcaaaaataa tgattgggat caagctagtt ttgaggtacc tgttgattat
    15121 gacattgagc cttttgttta ctttggtttt tttaactatg atccaagcca aaaagaggac
    15181 gtttttaaac tctttaaagt cattgattac aacctagaag atagcaagta ttataaaggc
    15241 ttagataagg ctgagagtga ccttgatact attgctatta tcaaagacaa gcgctttaga
    15301 caatcgtccg cagatgcttg tattgatgga gctttagagg gcactggtta tcaagttggt
    15361 aaagttgagg gcatttccga gatcaggacc cttagctatt attacatcag cccacgagct
    15421 gccatgatca agatgataga agcttttaac tgcgaattta atgtcagata cacctttgtt
    15481 aataacaaaa ttactagtcg ctatatcgac cttaaaaagc gatttggcaa gccaacagga
    15541 aagcagtttg agcatgggaa taacttatta aaagtcgtct atgaggaatc aacagatgac
    15601 atcgtgactt gtctgattgg ccgaggcaag ggcgaggaaa tccaatatga tgaaccagag
    15661 gcaaaggaag ttgaaggaca cttaccagag gcagaaaagc gtcaaggtta tggccgaaga
    15721 attgaattta gcgatgttgt ctggtcagtc gaaaaaggcg actcgataga caaaccagct
    15781 ggtcaaaact ttgtggcgct agatagtgcc agagaagaat acggattgtc tcaaaatggc
    15841 gagctaaaac accgatgggg ggtctttgtc aacgaggaaa ttgaggacaa ggcggaactc
    15901 ttaaaagcca catgggatca attgcagcgc ttatcaatac ccatcagaat ttacaaggcg
    15961 gaaatcttag atattggccc cgaaacgtgg aaaggtgact cagtagccat tatctacgat
    16021 gaggtaaaaa tagcttttga aactcgtgtt gatgagattg atattgataa gctaaacttt
    16081 aacaggtcgg tagtaactct cggtgattat agcgttgtcc aaaaccgcga agcaaggtca
    16141 cgcaaggaag ctgtccaaaa catgatcaat gatagcatag aaaacatcac cggccttggc
    16201 atgaacttac aagaattttt tcaaggtatt gaggaaaaaa ttgccactgg caaaaaagag
    16261 atggaagaca attggcgtaa ggttaacctt gaatttgata actttaaaaa attaatcgaa
    16321 caagagggac gtaactttag agagcgttta gaagctgaaa caaaggaact agatgaacgc
    16381 aaccaaaaag aactcgatga atttcgcgaa accctcaaaa atctgtcgct gcccgaggaa
    16441 gccattaaaa aaataaccga ggccatcaaa gttgatgata tcccatcgct aaaacaaagt
    16501 tttgacgagc tcaaaaacga agtcagcaag aacagcgaaa aatctcgctt aaatgctgaa
    16561 atcatcggca cgaacggtaa gacccgctat aacaaaaatc tcttggttgg tgaacctaat
    16621 cgcaccaaga cctatgatca ggattttgtg gagatagaag caaatgacgg tggttttaga
    16681 cgcggtgaga catacacgat tagctttagt cagacatgtg agttgctaaa aaaagtggct
    16741 atcacgctga cgcagccgca taacaaaggt ctcaagctgg tgctgacacc aaccaaggct
    16801 aagatggagg cgcagacttt tgacctaacc aaggacatag aggttatcag cgtctatcct
    16861 ttgagctaca gagctgtttt aacaggtgac tggtataaat ctaagcagat ggattttaat
    16921 gcggcagaag tgcaggattt agctctggag atgtcttata gagacgttgt cgatagcaat
    16981 aatgctagtt tgattttgga ttggtcctca aatccagatg ttatttttga tggaaatgga
    17041 ggtagttaat gtcagagact atatcagcta tagttgtgca taaaagcatg acaaaaaacg
    17101 agtgggagtc tagtgacatc attttgccac aaggccagct tgtctatgag tctgacacag
    17161 gccatagtaa atttggcgac ggtaaaaata gatatgcaga tttgatctat caaggtggac
    17221 cacctggggc acaaggtccc caagggccag ctggcgaaac cggtccacaa ggcccaccag
    17281 gccctactgg tcaacgtggg gaaacaggcc cacagggtcc acctgggcca caagggccgc
    17341 caggagcgga cggtaaaatg acgtttgagc agctcacacc agagcaaaaa cagcagctta
    17401 aaggtgctgg catacaaagc atatcattgg attatgaggg ctatttgaca atacagctag
    17461 ataatggcca atcgtttaga tcagatatta gcttaaaagg tcctcaagga gagccgggga
    17521 tcaatggtat ggacggtcca agaggcgcaa cgggtcccca aggaccagct ggtgatccgg
    17581 cgagcatacc tgacgatgtt gtcagacgtg gtgagttagc tgcatatttg cttaaatcag
    17641 agtataaagc caaaggcgca ggctctgg
//
LOCUS       DARYXS010000038        17277 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.039, whole genome shotgun sequence.
ACCESSION   DARYXS010000038 DARYXS010000000
VERSION     DARYXS010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17277
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.039"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..674)
                     /locus_tag="TV193_001049"
     CDS             complement(<1..674)
                     /locus_tag="TV193_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1513251.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGPQGPQGLSGDRGPIGQTGPQGKQGVSVQSASVDSEGYLTVLL
                     DNGQSFKSDSSLKGSKGDTGPKGADGKMTFEQLTPEQKQQLKGDKGDPGPKGDIGPRG
                     ATGPQGPKGEPGINGMDGPRGATGPRGLQGPLGKDAVLPDDVVRRGELAAYLLRSEYK
                     AKGSGSG"
     gene            complement(674..2815)
                     /locus_tag="TV193_001050"
     CDS             complement(674..2815)
                     /locus_tag="TV193_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1513252.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVRVTRERNGNYSLYIKYP
                     LDGVFASVFKEELKIKSDAGRRTKWQTFEINRVLRNSKDHIEIFARHISMRTQDIALK
                     PFVSGSSIDAESALEVWRDNLVGDDTFDVKSDILTLGSFNWEVDKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILHKQMGRKAPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEEASGKPHIGEQEQPEEQLVTLPEFILDGQYLDLYAQRRIQMVDLSSHFN
                     DDKKEPTVEEIRKLAQKYLKDNNVGAPKISIEVDYIDLSQTLDYQDFRVMEEVELCDI
                     VPLYYPKFGITTETEKVVEIVYDVYTDSNHTIKLGTIDQSISKSLTGGVTQRIETLEN
                     NQKVITNNQQQFELNLPKYLNDLNGTKIWYEKPDDNVEHKIGDFWFEKNGKYQRTWVW
                     DGNQWVKIIDTEDLNPNQRAFDEAMAEIEKLKQHQRELDERNQKELEEFRETLKNLSL
                     PEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTDGKTRYNKNLL
                     VGDPNRVKKIDEDFIEVEANDGGFRRGETYTISFSQTCELLKKVAITLTQANNKGVKL
                     VLIPTKAKMEAQTFNLSKDKEVISVYPLSYRAVLTGDWYKSKQIELNAAEVQNLALEM
                     SYRDVVDSNNASLILDWSPNPDVIFDGNGGS"
     gene            complement(2812..3519)
                     /locus_tag="TV193_001051"
     CDS             complement(2812..3519)
                     /locus_tag="TV193_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1513253.1"
                     /translation="MRYIEFNGKKSDSFGLLLERERSIKSTSNDVDLIEVDGRDGVLL
                     KDNGRLKAIEQDFPFSLVGDVAVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVSLVNGGTLQNLGNVQSKPILKIKGTGN
                     GVLTINGFETGLENVQGELIIDMERHLVYKDILSAWDNIVRTERHRMPLFDIGQNKIS
                     WTGNFTITAVPNWGVKV"
     gene            complement(3519..7178)
                     /locus_tag="TV193_001052"
     CDS             complement(3519..7178)
                     /locus_tag="TV193_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1513254.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAKVTELQNRLRSLATETSVFTRFGKAAERIGGKMKSFGDSVAGVDAAFTR
                     GVTAPIVAGAGYAIKAAVDYETAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGVKTGDILSFSRTMIYLGESTNLSAEEAATSIAKIANITGLASSEY
                     SRFGSAVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQSLSAIERAVASGGDNLNKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDDLGLSGIRQSNMLKSLGLASETLGKALDTSNKAWQENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIVKWGLIAAAAGPALSIFGKGVGIIGGTIQAMGKMSRGLGTLSGWLRTFRTGA
                     VAASAGAEAATASMGGMAGAVALLSNPVTWGVLLGGAAIVGIGLIADSMYKAQKRTEE
                     WGIKVSQVQANELQRFKNKVDEANLAMTTFGVRSANNLDKIKTSFKALADEIEALQNK
                     KLKKDLKLAEKLGLSQETIEEIRRQADQTVATVRGMSDKVVDIYRRAKEERRSLTEEE
                     KTVVTKNLNDMIQTELSLMNYSKKEKIAILKAMNGEIETLNYEQLKKAQEVAQKMIES
                     ENKTYKKRRSNLKEMYDNIKGDSETAVRAREEIHRQLETLEDSHTAKMESLGERYLKI
                     RKKLLEDPALDPRVKQAMIDSLDKEFEKLGLSFEKLSKRSEEASSKTKISMQDMTSSF
                     RASIGEAISSLQGWDNLTPQEKQLLIDGNKAVSEILNSKTLLEQWQALTPQQKELLAK
                     NLTQDPTLSAQQAIDNVKQRVPADVKASDKTAPDVASADRAVNRPKQKGPAIIRAQDN
                     ASSVASGVIGWLNSIPRTVTSTITTIVRKITGHKTGTDYHPGGLAMVNDQKGPLYREL
                     ITLPTGESFIPEGRNVILPLPRGSKVLRASRTKQLFSHYANGIGFNDTKIASLTTRLK
                     SVQDKGQVIVNTDPQLAELIKLLKDRDNRNVTNNYTLNATNRSNSDDMFNQENMRRLL
                     RELAYYTNGEKGRLA"
     gene            complement(7191..7340)
                     /locus_tag="TV193_001053"
     CDS             complement(7191..7340)
                     /locus_tag="TV193_001053"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513255.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            complement(7388..7714)
                     /locus_tag="TV193_001054"
     CDS             complement(7388..7714)
                     /locus_tag="TV193_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513256.1"
                     /translation="MYEITLKKGGVDKVFSKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMSVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            complement(7766..8356)
                     /locus_tag="TV193_001055"
     CDS             complement(7766..8356)
                     /locus_tag="TV193_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1513257.1"
                     /translation="MGKVKFGLRDFQYAVLGDDDQLKTKTGGIKSLPGMKSAKLDITN
                     ELVTVAADDGPYVVLSGGITETKLEIEVLDLTSDARKDFFGIKEEDGIEKYNKELTPN
                     DVACMFRTSDENGKAIWIGLLKGKFNIPGMEMQTKEGAPDPKSDTVTGNFVSRGKEGD
                     VIVIGRESASGFKLEKFKEFVFAGATDIKKGENFEM"
     gene            complement(8372..8797)
                     /locus_tag="TV193_001056"
     CDS             complement(8372..8797)
                     /locus_tag="TV193_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513258.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGPFKNGFKQGIFTYDIPD
                     NPVDLRKVDLAPFMRINTTLDGPADYADDEILCNEQRITINFWCKTASEADQISKCID
                     DILKKGGFERYTANEKPRYKDSDIDLLINVRKYRYFDFY"
     gene            complement(8794..9171)
                     /locus_tag="TV193_001057"
     CDS             complement(8794..9171)
                     /locus_tag="TV193_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1513259.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKAAVTEVAKEFEKALKANTPV
                     YEIETDERLQEDTVISGFKGANVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAAKVKEGLGL"
     gene            complement(9168..9515)
                     /locus_tag="TV193_001058"
     CDS             complement(9168..9515)
                     /locus_tag="TV193_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEL1513260.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAVRKDLYTCWAEVLKTQ
                     LRDFNYQSKYQNASNLPTNKDTKVFLIRYNPELSIDNTMFVEFGKRIYKIDKIESDES
                     GKDIIMISGVSMS"
     gene            complement(9512..9814)
                     /locus_tag="TV193_001059"
     CDS             complement(9512..9814)
                     /locus_tag="TV193_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1513261.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFDDDIIKEMIESAQEQICFAIEDG
                     STPEKFKGHAKFNLAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            complement(9959..11146)
                     /locus_tag="TV193_001060"
     CDS             complement(9959..11146)
                     /locus_tag="TV193_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEL1513262.1"
                     /translation="MFEEKIKEIKANIANLNQAIATKTTEVKNALESDDLETARSIKA
                     EIEEAKANLAEAENDLKLYEASIEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEALRFEGKDEVLIPLNQTTPVAPDTDGIKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKASGKWPVLQRATEKMVSVEELEKNPKLGKPQFKNVEWEVKTYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIAKVLKTFEAKAGVKTLDDIKKILNVDL
                     DPAYNVSFIVSQSFYQSMDTLKDENGRYLLQDSITSASGKVFLGKPVFVLSDDVIGKD
                     SAFVGDFKRGVLFADRKDLGLRWADNEIYGQYLQAVLRFGVAKVDDKAGYYVTFKPEQ
                     LPS"
     gene            complement(11171..11836)
                     /locus_tag="TV193_001061"
     CDS             complement(11171..11836)
                     /locus_tag="TV193_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEL1513263.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEQFPEDNSDI
                     VLEVNSNGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFKWVSGNSDDLDKASNALKSSDKAIVSAYVAKTGLSEDAIMDLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNSMLPQAVIDDYYRSRNKRKQEISNMLLEIEKEEIL
                     RGL"
     gene            complement(11814..13034)
                     /locus_tag="TV193_001062"
     CDS             complement(11814..13034)
                     /locus_tag="TV193_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1513264.1"
                     /translation="MSFFQPLGSSKVSYDDYVSSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRDPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDMLTAKQVKCFAHDVIHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILKMKGAHISGEARKR
                     ARVEFEKMREGAIGGSPLVFDDTQEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLSDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLVELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            complement(13068..13334)
                     /locus_tag="TV193_001063"
     CDS             complement(13068..13334)
                     /locus_tag="TV193_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513265.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEALRNQNRQIAELRSIIQ
                     QNAQATNREFAAVKSATLDNQAAIKKIGDEVYYIKQNYKRKWRK"
     gene            complement(13327..13497)
                     /locus_tag="TV193_001064"
     CDS             complement(13327..13497)
                     /locus_tag="TV193_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513266.1"
                     /translation="MIGFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIFL
                     AIYVDSVGGKHE"
     gene            complement(13494..15248)
                     /locus_tag="TV193_001065"
     CDS             complement(13494..15248)
                     /locus_tag="TV193_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL1513267.1"
                     /translation="MTIEYDYSAIGDIYKDDAFYYAKKVVDEEIKASKKVFKACLRHL
                     NDLKKIDDDNFKFIYLPKKAIDPIIFIELLPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDEEIV
                     DDGYFGYVAEQDNEGEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKQSWELARIDKPDTHKRRVWLGVDVGRVSDLFAITPVIM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLERQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEVNGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KNGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTSEKILGGETLF"
     gene            complement(15263..15730)
                     /locus_tag="TV193_001066"
     CDS             complement(15263..15730)
                     /locus_tag="TV193_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEL1513268.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            complement(15893..16228)
                     /locus_tag="TV193_001067"
     CDS             complement(15893..16228)
                     /locus_tag="TV193_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL1513269.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDRKTKQFYN
                     SKIWRETSKQVLLQSDYICAMCGGEATMTDHIVSVKKDWNKRLDWNNLQASCKACNDC
                     KAIRERRKT"
     gene            16344..16529
                     /locus_tag="TV193_001068"
     CDS             16344..16529
                     /locus_tag="TV193_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEL1513270.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPLHNK
                     DLGKGLEDTILKQAGLK"
     gene            16581..16958
                     /locus_tag="TV193_001069"
     CDS             16581..16958
                     /locus_tag="TV193_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEL1513271.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGKDFQEAYEMAVEVLG
                     FALEDYTDYPKASSVSDLKEQYRDSDIALIGIDMIAYMKKYHSKKVRKNVTIPEWLNK
                     AAEDENLNFSQVLTEALELKLQA"
BASE COUNT         4625 a         3968 c         2901 g         5783 t
ORIGIN      
        1 cctgatcctg agcctttagc tttgtattcc gaccgtagca gataagctgc tagctcacca
       61 cgtctaacaa cgtcgtcggg caaaaccgca tcttttccta gtgggccttg cagtcctcgg
      121 ggacctgttg cacctcttgg accgtccata ccatttatcc ctggctctcc tttaggacct
      181 tggggccccg ttgcgcctct aggaccaatg tcccctttag gacctggatc acctttgtcg
      241 ccttttagtt gttgcttttg ctctggcgtc aattgctcaa aagtcatttt accgtcagca
      301 cctttaggac cagtatctcc tttagatcct tttaagctgc tatcagattt aaaggactgt
      361 ccgttatcta acaaaacagt taaatagccc tcactatcta ctgatgcact ttggacactg
      421 acaccttgtt taccttgtgg acccgtttgt cctatgggac cgcggtcgcc acttagtcct
      481 tgtggacctt gtggtccagg tggcccacct tgatagatca aatctgcata tctattttta
      541 ccgtcgccaa atttactatg gcctgtgtca gactcataga cgagctggcc ttgtggcaaa
      601 atgatgtcac tagactccca ctcgtttttt gtcatgcttt tatgcacaac tatagctgat
      661 atagtctctg acattaacta cctccatttc catcaaaaat aacatctgga tttggggacc
      721 aatccaaaat caaactagca ttattgctat caactacgtc tctataagac atctccagag
      781 ccaaattttg gacctctgcc gcatttaact caatctgctt agatttatac cagtcacctg
      841 tcaaaacagc cctgtagctc aaaggataga cgctgatgac ctccttatct ttacttagat
      901 taaaggtctg cgcctccatc ttagctttag tcggtatcaa cactaattta acacccttat
      961 tattagcttg cgtcaacgtg atagccactt ttttgagcag ctcgcaagtt tggctaaagc
     1021 tgatggtgta agtctcaccg cgtctaaagc caccatcgtt ggcttctacc tcgataaaat
     1081 cctcatcaat ttttttgaca cgattagggt cgccaaccaa taagtttttg ttgtagcggg
     1141 tcttgccatc tgtcccgata atctcagcgt ttaatcgtgc ggtctcgctc gtctcactga
     1201 ctttgttttt gaggtcgtca aacgactgtt taattgacgg tatatcatca actttgatag
     1261 cctctgttat ctttttgatg gcttcctcgg gcagcgacag atttttgagg gtttctctaa
     1321 actcttcgag ctctttttgg ttgcgttcgt cgagttctcg ctggtgctgc tttagctttt
     1381 caatctcggc catagcctca tcaaaagctc gctgattagg atttaaatcc tcagtatcaa
     1441 tgatttttac ccattgattc ccgtcccaaa cccaggtacg ctgatattta ccgtttttct
     1501 caaaccaaaa atcgcctatc ttgtgctcaa cgttgtcatc tggtttttcg taccatatct
     1561 tggtaccgtt tagatcgttg aggtatttgg gtaaattaag ctcaaattgc tgttgattat
     1621 tagtaataac cttttggttg ttttccagcg tctcaatccg ctgcgtaaca ccacctgtca
     1681 gactcttaga gatagattgg tcaatcgtgc caagctttat tgtgtgattg ctatctgtat
     1741 agacgtcata gacaatctca acgacttttt cggtctcggt tgtgatacca aactttggat
     1801 agtaaagcgg tacaatatcg caaagctcga cctcctccat aactctaaaa tcttgatagt
     1861 caagcgtctg tgacaggtcg atataatcaa cctctatact gattttaggt gcgccaacat
     1921 tgttatcttt aagatatttc tgagccagct ttctgatttc ttcgactgtc ggctcttttt
     1981 tgtcatcatt aaaatgacta gataaatcaa ccatctgtat tctgcgttgg gcatataagt
     2041 caagatactg accatctagg ataaattcag gcagcgtcac cagttgttct tcgggctgct
     2101 cctgctcacc gatgtgcggc ttaccagagg cttcctcttg cggctttggt tgtggcgtat
     2161 atcttacgta aggatagatt gaggtataat tgccatcaag caaacgctcc tcttccacgc
     2221 tgacgatatt gcggccatac tccaaaaccg taggggcctt acgccccatt tgtttatgta
     2281 agatgattgt gcgattgtca aactcgtact caccaccgta aacatctaag atagagccag
     2341 caacaccccc gagagcgcct cttgcattgc ctatcttgtc aacttcccag ttaaagctgc
     2401 ctagtgttaa aatgtcgctt ttaacatcaa aggtatcatc accgacaaga ttatcccgcc
     2461 aaacctccag tgccgactct gcgtcaatgc tagacccgct cacaaatggt tttaaagcga
     2521 tgtcctgtgt gcgcattgag atatgccttg caaaaatctc gatgtggtct ttactgtttc
     2581 gcaacacccg attgatctca aaagtttgcc attttgtcct tcggccggca tcagacttaa
     2641 tcttaagctc ctccttaaag accgaggcaa aaacaccatc aagtggatat ttgatatata
     2701 gcgagtaatt accgttgcgc tcacgagtaa ctcttacctc ataagcgtct gcgatctcac
     2761 caaggccaaa agtcctaaat ttggtttctt tggcctcgta taaaactggt atcatacttt
     2821 aaccccccag tttggcactg cggtgatagt aaagttacca gtccatgaga ttttgttttg
     2881 accaatatca aatagtggca tgcggtggcg ttctgtccgc acaatgttat cccaagcaga
     2941 caggatatct ttatagacaa ggtgcctctc catatctatg atgagctctc cttggacgtt
     3001 ttcgaggccc gtctcaaaac cattaatggt taaaacaccg ttgcctgtcc ctttgatttt
     3061 taagataggt ttagactgca cattaccaag gttttgtaga gtgccaccat taacgagaga
     3121 cacctcttgc ttaccagttt ttaggtattt gatagggtgg attaagaaat taacctttaa
     3181 tctaccaaat tgcttaagta tctcgtctat ttcaaaaaga ttgacaacac tagcccgata
     3241 gatatagtcc ttgtcccaag acaaagctaa gtcgtgccaa cccttgacat gtaaccattc
     3301 acttattttt tgctgattga cagccacgtc accaaccaaa gaaaaaggaa agtcttgctc
     3361 aatagctttc aaacgaccat tgtcttttaa gagtacaccg tcgcgtccat cgacttctat
     3421 taaatcaaca tcgttactcg ttgacttaat agatcgttca cgctctagca aaagaccaaa
     3481 gctatcactt ttcttaccat taaattcaat gtatcgcatt aagccaacct ccctttctct
     3541 ccatttgtat agtatgcaag ttctcttagg agacgtctca tgttttcttg attaaacata
     3601 tcatcagagt tactcctgtt tgtagcgtta agtgtgtagt tgtttgtgac atttctgtta
     3661 tctctatctt taagtagttt aatcaactcc gcaagttgag gatcggtatt gacaatcact
     3721 tgtcctttat cttgcacaga tttaagacga gttgttaagc tagcgatttt ggtatcatta
     3781 aaacctattc cgtttgcata atgcgagaat aattgttttg tacgacttgc tctaagaact
     3841 tttgaccccc ttggcaaagg aagaatgaca tttcttcctt ccgggataaa ggattctccc
     3901 gtcggtaaag tgatcaattc cctatacaaa ggaccttttt ggtcattaac catcgctaaa
     3961 ccgccagggt ggtaatcagt tcccgtctta tggccggtta ttttacgaac aattgtagtt
     4021 attgtcgatg tcactgtacg aggtatacta tttagccacc caataactcc actagcaaca
     4081 ctactagcat tatcctgtgc tctaataata gctggacctt tttgcttagg cctgttaacg
     4141 gctctatcgg cagaagcgac atctggagca gtcttgtccg aggctttaac atcagctggc
     4201 actcgctgct taacattatc gattgcttgt tgagctgata acgttgggtc ttgagttaga
     4261 tttttagcta acagttcttt ttgctgaggg gtcagcgctt gccattgctc aagtaaagtt
     4321 ttactattta ggatctcact gacagcctta ttcccatcta tcaacaattg tttttcctgc
     4381 ggcgtaagat tgtcccaccc ttgcaatgaa ctaatggctt cgcctatcga tgctctgaat
     4441 gagcttgtca tgtcttgcat gcttattttg gtcttagagc tagcctcttc actcctttta
     4501 gataactttt cgaaagataa tcctaatttt tcaaattcct tgtctaagct atcaatcata
     4561 gcctgcttaa ctcgtggatc taaagctggg tcttccagaa gttttttacg aatttttaag
     4621 tatctttctc ctaaactctc catttttgct gtatgactat cttccaaggt ctccagctgt
     4681 ctgtgaatct cctctctggc tctcacagca gtttcagagt ctcctttgat attgtcatac
     4741 atttctttga gattacttcg tctcttttta taagtcttgt tttcgctctc tatcatcttt
     4801 tgagcaactt cttgagcttt tttaagttgc tcataattaa gcgtttcaat ctctccattc
     4861 atcgccttca aaatggcgat cttttctttt ttagagtagt tcatcaaaga taactcagtc
     4921 tggatcatgt cattcaaatt tttagtgaca acagtctttt cttcttcagt caaacttctt
     4981 ctttcttctt tggctcttcg gtaaatgtct acaactttgt cagacatacc tctaactgtt
     5041 gccacagttt ggtcagcttg acgcctaatc tcctcgattg tctcttgact aagacctaac
     5101 ttttcggcta gttttagatc cttcttaagt tttttgtttt gtaaagcctc tatttcgtct
     5161 gccagtgctt taaaagatgt cttgatttta tcgagattat tagcactcct gactccaaat
     5221 gttgtcattg cgaggttagc ttcgtcaact ttgtttttaa atctttgcaa ttcattggct
     5281 tgcacttgac tcactttaat tccccactct tctgtgcgtt tttgggcttt atacatgcta
     5341 tcagcaatta aacctatacc cacaatggct gcaccaccta acagcacacc ccaagttaca
     5401 ggattactta ataaggcaac cgcgccagcc attccgccca tagaagctgt ggcagcttcg
     5461 gctcctgcac tagctgctac tgctccagtt ctgaatgtcc tcaaccagcc tgataaagtg
     5521 cctaaccctc gactcatttt gcccatagct tgaatggttc ctccgataat gccaacgcct
     5581 ttaccaaaga tagataaagc tggaccagct gcggctgcaa taagccccca cttaacaatt
     5641 tgttgttgtt gctctttgtc aagcgagtta aattgcttag ctaaatctgc tgccatttga
     5701 ataattggtt ttcctgcttc gagcccattt cttagagcgt caaccaaagg gccaccaaat
     5761 tcaatagcta catcattaac ttcattctta agcattttta gcttagactc tgttgtctca
     5821 tagcgtttat tagcttcgtc agttaaagca gtgttttctt gccaagcttt gtttgaggta
     5881 tctagagcct tgcctaaagt ctcagatgct aatcctaaag atttcaacat gttagactgg
     5941 cggataccgc ttaatccgag gtcgtcaagc acttttgtag cactttcacc ttttttatca
     6001 agctggccaa gccccttaat aaactcttgc aatgcaacaa ttggcttctc tttccatgct
     6061 ctcgcgaaat cagcagatga catattggca atttgagcaa atttatttaa attatctcct
     6121 ccagatgcaa ctgcacgttc aatagctgac aatgattgag tcattgctgt accaccagct
     6181 tctgcctcta taccaacgct tgacattgct gttgctaaag ctaacatctc ttgattggtt
     6241 aatcccgcaa gcttaccaga cgcagcaatg cgattagtca tcgctacgat gtctctttca
     6301 gttgttgcga agttattacc caacgcgaca acagcactac caaagcgaga atactccgat
     6361 gaagccagac ctgtaatgtt tgcaatttta gcaatagacg tcgccgcttc ttctgccgat
     6421 aaattggtgg actctcctaa ataaatcatt gtacgagaga aactaagaat atctcctgtc
     6481 ttaactccta attgacctgc cgcctccgcg acatgagcga tttcaacagc actggctggc
     6541 aactctttgg ccatttgtct aataccctgt gatagcttcg cataagatac tgtcgccgtc
     6601 tcatcaactg tctttttaac accagcaaat gcagtttcat agtcaacagc tgctttaata
     6661 gcataaccag cgcccgctac aatcggagcg gtgactcctc ttgtaaatgc agcatcaact
     6721 ccagctaccg aatcgccgaa tgacttcatc ttcccgccga ttctttcagc agctttacca
     6781 aatcttgtaa aaacgctagt ttcagtggct aacgatcgta atctgttttg caattctgtg
     6841 actttcgcag cagtctccaa catggctgat ttagcgccaa tcaatttttg cttttgctca
     6901 gcagtagcgt tattaacatc acctatctct ttttttaggt cgctatattt ttgcgactga
     6961 gtttttagta attcttggta accttttaat gcactacctg tttcagcata gaccgcttta
     7021 agacctttga tccgcccgcc atgcccttga aagctctttt caactgcttt taacgagtta
     7081 tctaagcctt tcatgtaggt ttttaggttt cttgtgtttg acataaatgg tgatatgtct
     7141 agtgtagccg ttgctactaa atcacctata ttccccattt atcctccttt ctagccgaaa
     7201 aggaatggga atgccttatc caaggtcgtt tcaatcactt cttctttttc gacagtttca
     7261 atttctagcg cttgtaccat caattcaata tcagataagc gcattttttt aatatctaaa
     7321 atggtataac cgtttttcaa aaggctctgt atccacaaga gtaagttttc tttagcctct
     7381 tgtggggtta ttgttccttt ttttcgcttt cgtcttcctc ttgctctcca ccgagtgctg
     7441 caatgtacag gtcattaagt gtatttaaaa cactcatgtc agattgcttt aaatcatcga
     7501 ctgtaaattg acctgcgtac atatcaacaa acatttgcaa gtaagattcg ttaagttttc
     7561 tatgcgcttt agaatctaag cgtcttttct catcgctaaa cacagcgctt tgtctaactt
     7621 gatgctcaac agccaacaaa ttatcctcaa cgttaataaa gtcctttgaa aaaactttat
     7681 ctacaccacc tttttttaag gtaatttcgt acatatctac tccttatcaa aaataaaagg
     7741 ttggatttta aatccaacct gattgttaca tttcgaagtt ttcgcctttt ttaatatctg
     7801 tcgcaccagc aaacacaaat tctttaaact tctctaattt aaaaccacta gcactttcgc
     7861 gaccgataac aataacatct ccttcttttc cacgagacac aaagttgcct gttacagtat
     7921 cagatttagg gtctggcgct ccctctttag tctgcatttc catacccgga atgttaaact
     7981 taccttttag caatccaatc cagatggctt tcccgttttc atcgcttgtt cggaacatac
     8041 aagcaacatc gttaggggtc agctccttat tgtatttttc gattccgtct tcttccttaa
     8101 ttccgaagaa gtcttttcgt gcgtcagatg ttaagtctaa cacctcgatt tcaagttttg
     8161 tttctgtaat acctccagat aaaactacgt atggaccatc atcagcagct accgtcacta
     8221 attcgtttgt aatatcaagc tttgctgatt tcatgccagg tagtgatttg atacctcccg
     8281 tttttgtttt taattgatca tcatctccga gtactgcgta ttggaagtca cgtagtccaa
     8341 attttacttt tcccattttt tcctctttct tttaataaaa atcaaaatag cggtatttcc
     8401 ttacatttat cagtaagtca atatcgctat ctttatatct tggtttttcg tttgcggtgt
     8461 atctttcaaa accgcctttt tttaaaatat catctataca tttgctaatt tggtcagctt
     8521 cagaagctgt tttgcaccaa aaattgatgg tgatccgttg ctcgttacac agtatctcat
     8581 catctgcata atcagcagga ccgtctaatg ttgtgttgat tcgcataaaa ggcgctaaat
     8641 ctaccttacg caagtcaact gggttatctg gaatatcata agtaaatatg ccttgcttaa
     8701 acccattttt aaaaggaccg cctctgagcc tatccaacaa ctcatttagc gtcttatcgt
     8761 tacttaataa tttataagct gctgtttcag caatcaaagt cctagtccct ccttaacttt
     8821 tgctgcgtag atttgtttag cttttggtgt catctgattg atggtttttt ccttaaagtc
     8881 ttgtccgcgt tggtaaatgg tcccatcgtt aggatagtgc gcacgccaac cagtcgcttt
     8941 gccatagcca atttccttgg atacaattcc aacattagct cctttaaaac cactgataac
     9001 ggtatcttcc tgtagccgct catctgtttc aatctcataa acaggggtat ttgctttaag
     9061 tgctttttca aattctttgg caacttcagt tactgctgct tttgcggttt ttggtgcttt
     9121 tacttcaagc tttgtcagat tagccaatat ttcatctaaa ccttttgtca tgacatgctt
     9181 actccactta tcatgataat atctttgcca gattcgtcag attcgatttt atctatctta
     9241 taaatgcgct tgccaaactc aacaaacatc gtgttatcta tagataattc agggttatac
     9301 ctaattaaaa aaaccttagt atccttattt gttggcaaat tgctagcgtt ttgatacttt
     9361 gattgataat taaaatctct caactgcgtt tttagcactt ctgcccaaca agtatacaag
     9421 tcctttctga cagcagatac tacttcacca tcttcatttt gcccgcctga ttggctaaaa
     9481 atcgttatcc tgacgttcat cttgcgtgta atcacgaatc atcacctctc aatcgcaatt
     9541 gatggataat gtttaaaaca ccatttgcca acggatagcg aaaactatcc gcagacaaac
     9601 cgcgatggtc atactcttcc ttgacttgct ttttgacagc taaattaaat ttagcgtgac
     9661 ctttgaactt ttcaggagta gaaccgtctt ctattgcaaa acagatttgt tcttgagcag
     9721 attcaatcat ttctttgatg atgtcgtcat caaaatcaaa gtcaatttta caatagagtt
     9781 ttacactgtc taataactct tttgatacag ccatagctat acctcttcaa cgcctgcaag
     9841 ttttaataaa tcagatttta atgttttccc attaaagtca attcccttgc ttgttaaata
     9901 gcgcttaatc tcctcgacag tgcttttgct agttggtttc gccacttctt cagtggcctt
     9961 atgagggcaa ttgttctggt ttgaatgtca catagtatcc agctttgtca tctaccttag
    10021 cgacaccaaa gcgaaggaca gcttgcaagt attgaccgta aatttcgtta tctgcccaac
    10081 gaagccctaa atctttacga tcagcaaata acacgccgcg cttaaaatct ccgacaaaag
    10141 ctgagtcttt accaattacg tcatcagata ggacaaatac cggttttcca agaaacactt
    10201 tgccagacgc agaagtgatt gaatcttgaa gtaggtaacg gccattttcg tcttttaaag
    10261 tatccatgga ctggtaaaag ctttgagata caataaatga cacattgtaa gctggatcta
    10321 aatctacatt taggattttt ttgatgtcat ctaatgtttt gacaccagct ttagcctcaa
    10381 atgtttttag gactttagca attgcatcat tagttgtatt aactttcatt tgaccgattg
    10441 tttcagcaac aataccaacc aaatctacat ctgcatcatc aattgactct tgggataacg
    10501 ggatagctcc acgataagtt ttaacttccc actccacgtt tttaaattgt ggtttgccta
    10561 gttttggatt tttttccaat tcttcaacgc ttaccatttt ttctgtagca cgttgcaata
    10621 ccggccattt accagatgct ttcttagctg ggtggatgct agtaaattgt ttcaaatcaa
    10681 caactgtctt aacttcacga gctggtgtgt atagaatttc ttcgctagaa acaggtttca
    10741 cgtctgtctt tttaattcca tctgtgtcag gagcgactgg tgttgtctga ttaagcggaa
    10801 taagaacttc atcttttcct tcaaaacgca aagcttcatt agttactgtt ccttttgaac
    10861 gaataaattc gttaacgctt tcgcggtatg ttttagtttc ttgtggcact tcttttcctc
    10921 cagtattttc tgcaccgcct ttttcaatgc tagcttcata caatttcaag tcattttctg
    10981 cttctgctag gtttgcttta gcttcttcaa tttctgcttt aattgagcga gcagtttcaa
    11041 ggtcatctga ttccaaagca ttttttactt ctgttgtttt agtagcaata gcttggttta
    11101 aattagcgat attcgcttta atttctttga ttttttcttc gaacataaat tcctccaata
    11161 aaaaaagagc ttatagccct cgtaaaattt cttctttttc aatttctagt aacatgttgc
    11221 taatctcttg ttttcgtttg ttcctacttc tgtaatagtc atcaataaca gcttgcggca
    11281 acatggaatt atcaatgcta gcaactgctt caaaagacat aacttcgtcc gcaaaacctt
    11341 tttctacggc atcttgagcg gacataaacg tttcatttcg cattaaatcc atgattgcat
    11401 cttctgataa ccctgttttt gcgacatagg cactcacaat agctttatca cttgatttta
    11461 aggcattaga agctttgtct aggtcatcac tattaccaga cacccattta aagagtgctt
    11521 tatgcaccat catttgagct gtaggactca tgacaacctt atccgcaccc ataacagcca
    11581 cagatgctgc acttgcagcc atgccagtaa tttctgcagt tacttttcct ttgtaatttc
    11641 gtaaagcggt atagatttca ctcccaactg tcacaagtcc accgtttgaa ttaacttcca
    11701 aaacaatatc gctattatct tcaggaaatt gctcaatgat acttttagca cttgctgctt
    11761 ccattccgta atagtcgtaa acttcttgag agttatttgc aattagtggt cctttaagat
    11821 ttatcctctt tggcatttac ctcacctcct ttccctttga taccaacctt gtcttgatat
    11881 tcttcttttt tgtctaaaaa gacgtagttt agactagact ggtacctatc catgtttgga
    11941 tctgttgatt tttgcttacc aagctctacg aggccttggt taggcgtcaa gatttggtta
    12001 ttaaccaatt tgacaatctc atcaacattg cgacctgtga cgcttcgtgt atcaaactcg
    12061 atacgataca aacgcctatc cttatcactt agcgtcttaa gtcctaactc acttgtgata
    12121 gcatcaaaat aaaatggcaa atcattcgtg acataatctt ccatcaactg ggcaacagat
    12181 tgatttggac tattaacacc aagcttgtag ctgggaaccc gcaaagcttt tgcgatttgc
    12241 gccgttgaaa aattgttact tgtaattaat tgcaatacgt tagtatcgat ttcaagcggc
    12301 gtgtattctt gcgtatcatc gaatactaaa ggactaccac caattgcacc ctcgcgcatt
    12361 ttttcaaatt caactctggc tctcttacgt gcttcaccgc ttatatgagc acctttcatt
    12421 tttaagatgc cactagaaaa accatctttg aagaatttaa ttaaggtatt gatgccgccg
    12481 gtttgcaaat caatctcatc acctaaagac agtagcgggg accttcccaa aattgtatcg
    12541 tgactaaaaa acttccagtg gataacgtca tgggcaaaac atttaacctg ttttgctgtc
    12601 aacatatcag taaacgtata aactatctcg tggttatctg tctcctcaac agtcgtttct
    12661 gacggcctgt aaaattggaa ttgcaaagct tggttagtct ttggatctct caaaatacgc
    12721 gaaaaagaat taccagtcaa aatggcattt actgccatag caaacttcca ggtcctagcg
    12781 ctcgcatttt ttgtggattt aacatttaaa agataattaa tatcctcatc atggataatg
    12841 tccccattaa catccttttt aacaagcgga aacctagcaa tatccccagc tataatagac
    12901 gttgctgtta aaatatcgct attcttcaaa gccgacactc ctaagtattt ttgggagaca
    12961 tcgccagcta aaacagatga tacatagtca tcataggaca cctttgaact gcccaaaggt
    13021 tgaaaaaaac tcatcgattt ctcacctcct ttctaaacca ttaacatcta tttccgccac
    13081 ttgcgcttat aattttgctt gatataataa acctcatccc caattttctt aatggctgct
    13141 tggttgtcta gcgtcgctga tttaactgct gcaaactctc tatttgtcgc ttgggcgttt
    13201 tgttgtataa tcgatctcag ctctgcaatt tgtctgtttt gattcctgag tgcttcagct
    13261 tgcatagcat tttctgcaac aagcatcaca accgctgttt ccaatttacg ttttttctta
    13321 atgcgtttat tcatgttttc ctcctacgct atctacatag atagctaaaa aaattaaaat
    13381 aagaccacta gcgataaaac caactttatc accaaacaaa aacaacccat acatcaataa
    13441 acctagtcca gctaacaaga ttaatgtatg tatgtttttt aaaataaaac caatcaaaac
    13501 agtgtctctc ctcctaaaat tttctcactt gtccagtaac cagagccgtc aaatggctct
    13561 aagtaacaaa ctgcataccc gtctaaagca gcgtccagag ggtctatctt attgctattc
    13621 ttattcttat caatcctcat gccattgtta tcagtcttga tataagcgtt attaacagcc
    13681 attgttagca atggattgcc agagtgcttt attttgccat tcttgagatc atcacgaaat
    13741 tgctttgttg gcatgttcaa aaccattgtc gtttgcgaaa cctctatgag aggccattct
    13801 gggtgccttt tctcaatcat cgtaagcagc gttccaaatt ggtaagggtc aaaacagatt
    13861 ccgttaactt cccagtcatt cgaatagacc atctcctcta ttttttctaa aactctctca
    13921 tcatcaataa ccccactttc taatgttgtt atctcgcaat agccttgacg ttctaaatta
    13981 ctgtaagaca caccatcacg cttttcttta gccgttaacc catactttgt cgcaacaaaa
    14041 gaaaaactgt caatatacca aaaatcgtcc atcataataa ctggtgtaat agcaaataag
    14101 tcactaacac gaccgacgtc cacacctagc cagacccttc gtttatgtgt gtcgggttta
    14161 tcaatacgag caagttccca agattgctta tcaatatatg attcctcact cgactgccgc
    14221 cacatgttaa agtttttgat aagtaccttg ttaatttcac ctgtttcaag agacactcta
    14281 cgacgcgttc tcaggtaatc cattagctta tcgtgcaaag cttcaacctc gaggattgga
    14341 tttgatttta tccaatttga ttcatcttta atttcacctt cgttgtcttg ctctgcgaca
    14401 tatccaaaat agccatcatc tacaatttct tcgtctaaaa ttttagtgat gtacggatac
    14461 tcaattgtgt gcatggggac attcaaatcc ataccagctg ttgagataat caagataaac
    14521 ggattatcaa gctgaccttg accggattct aaaagctcta acatttcgtt tgtctttgat
    14581 gccgcaaact catctaaaac gccaacgtaa ggctcgaacc catcgactgc cccagtatct
    14641 cgactaagag ccctaatata agattcatca tgtaagtttt tcagctcatc acgaacaatt
    14701 ttcgtggctt ttctgacatc agcgtccttt gctcttaaag atgagagttg cttctttgcc
    14761 atgtcccaag caattttagc ctgtgtacgg tcattagctg tacaaaacaa ttgtctactc
    14821 atagatggat tatgcccaaa caaaaattca taaagcaaga taccagctat cagaattgtt
    14881 ttgccatttt tacgagcaac cgaaatcata gcttttctaa agcgtcttaa ggaatgatct
    14941 gttttctttc gccatccgta taaattcccg ataataaact tctgaaacat cgctaaagga
    15001 taaggctttc ccgtcttaac gtctggcaat agctcaataa aaattatggg gtcaattgct
    15061 ttttttggta aatagataaa tttaaaatta tcatcatcta tttttttaag gtcattcaaa
    15121 tgtcttagac aagctttaaa gaccttctta cttgctttaa tctcttcatc aacgaccttt
    15181 tttgcataat aaaaagcgtc atctttatag atgtcgccga ttgctgaata atcgtattct
    15241 attgtcatga ccccctttct ctctatcctc caaatttatc aaatatactc ttaggttttt
    15301 cttcttcctt cggaataaac atcttcatgc gactatctac cgttagtcct aattgactgg
    15361 cactacttct aatattcgca gtggcttttt ccaatgttaa aataagcgga ctaggaataa
    15421 tgcctttgtc tggatcattc gtaaaataac caacctcatc tagttttcta cttgtttctt
    15481 tgtagatagc ataccatgtg caatataact ctaatagccc tctatcgaga tttcttaggg
    15541 gtaggttttg gaggtcttct atgattctcc tatactcgta cttagctaca ttattaaagt
    15601 gttcaggagg tgtcttttgc aactttttaa gaccgtcaga cgccttattt tgcgcggttt
    15661 ctcgcactat tttttcttct ttcgtaagat gcttttttgt cgtttcaact agctttaaat
    15721 ttcttcccat aagacctcct ttacacaaac tttacagttt caaaaatttc aaaaagggat
    15781 ttttttgcac agaaaagggc gcgttcttaa gtttccgaac aatatagccc cgttaaaaaa
    15841 taggcggggt atttcccgaa caatgattgc gtatgttact ttttatgtac gtttaggttt
    15901 tccgtctctc tcttattgct ttacaatcgt tacaagcttt acaacttgct tgcaagttat
    15961 tccaatctaa tcttttattc caatctttct taactgagac aatgtgatca gtcatcgttg
    16021 cttctccacc acacattgca cagatataat cactttgcaa taagacttgc ttacttgtct
    16081 ctctccaaat cttagagtta taaaactgct tagtcttcct atcatacttc catctgttac
    16141 gattatagtc acgatactca gctgacctat catcgtagtc aacagtcgtt cgtctgccac
    16201 ccgcaattgt taacttctgc ggcctcatac cctaacctcc ataataaaaa atagaaaaca
    16261 aaaatacgca ttttttgcgc atacctattg acaaccatgt ttattgcgtg tataatataa
    16321 gtatagaaag tgaggtaagc aatatgccaa tgaccccaaa gcagatgata aaactgctaa
    16381 aaaagaatgg gttctatgaa gtcagtcaaa acggaagtca caaaaaattc cgagataata
    16441 acggacatca aaccattgtt cctctacaca acaaagacct cggaaaaggc cttgaagata
    16501 ccattctaaa gcaggcgggt ttaaaataat ccgcttgcca gatggtttgc ttatctcaca
    16561 gtgatcgaag gagaatcatt atgttaatct atccagctac attcacacaa gacacagact
    16621 atatcatggt tacatttcca gatgtacctg aagcaattac tcaaggtaaa gactttcaag
    16681 aagcttacga aatggctgtc gaagtcttag gctttgctct tgaagactat actgactatc
    16741 caaaggctag ctccgtttcc gacttaaaag aacagtatcg tgattctgat attgctttaa
    16801 tcggcatcga tatgattgcc tacatgaaaa aataccactc taaaaaagta cgtaagaacg
    16861 tgactatccc tgagtggtta aacaaagcag ccgaagatga aaatctcaat ttctcgcaag
    16921 tcctcacaga ggcacttgaa ttaaaactac aagcataaga gccacttagt ggttcttttt
    16981 tgcataataa aaagccatca cgatgtgatg actagcacag gaacagtcgg aatcgaaccg
    17041 acttacaacc gttgtcccta ctaaccacaa gcaaggttgc gacccttgtt tttgaacttg
    17101 cggttaatca taaaaaccca cacatcagaa cgtgtctgcc tttaaagggg tatggggtcg
    17161 cgcctcttct gggcgctgat tgagacggca ggattcgaac ccgcacgtcc cacatacata
    17221 aaataacaag tttgatcgta gttaaagtca gcgactaaat aaatagtcag ttggtaa
//
LOCUS       DARYXS010000039        17104 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.040, whole genome shotgun sequence.
ACCESSION   DARYXS010000039 DARYXS010000000
VERSION     DARYXS010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17104
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.040"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(19..1290)
                     /locus_tag="TV193_001070"
     CDS             complement(19..1290)
                     /locus_tag="TV193_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEL1513272.1"
                     /translation="MPDNLAIRMRPRTITEVIGQQHLVGEGKIIDRMVKANRLASMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATIDNKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKSKQDFLLPLLEHGHIIMIGATTGNPFFSVTPAIRSRVQIFELEPLSPEEIKQALK
                     LAITDKERGFAFDVTLDEAAFDFIATATNGDLRAAYQSLDLAVMSTQPDTEGIRHISL
                     NTVENSLQRSYITMDKDGDGHYDILSALQKSIRGSDVNASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYM
                     AMDAALADLRQHGHLPIPRHLRDGHYAGSKELGNAQHYLYPHAYPEKWVKQQYLPDHL
                     VKKNYFNPNETGKYERALAANKARIDKLSSS"
     gene            complement(1283..1891)
                     /locus_tag="TV193_001071"
     CDS             complement(1283..1891)
                     /locus_tag="TV193_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEL1513273.1"
                     /translation="MILLIDNYDSFTYNLAQYLSAFDQTIVLTNQDPKLFDLAKQADA
                     IVLSPGPGWPKAANQMPSLIRAFYDQKPMLGVCLGHQAIAEALGGRLRLAKRVMHGKQ
                     SILERQAPAKLFQQLPKQLTVMRYHSIVVDDLPADFVITARDFEDNEIMAFEHRQLPL
                     FGLQFHPESIGTADGRTMIANFMAVVKKHHSQQKQGREEYNA"
     gene            complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TV193_001072"
     CDS             complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TV193_001072"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEL1513274.1"
                     /translation="MHIKTIIDFKELGQRYIFQAPIVELVAKQIDQVGQVLEQVNQFQ
                     DLGYYVVGYLSYEAAACFDKKLTTHNKRLGQEYFAYFTVHDSCQLEDFPLYHDSMTIP
                     NSWTSATQEEAYQEAIAQIHQEMRQGNTYQVNYTIQLSQRLNAKDSLAIYHQLVIEQA
                     AGYNAYIAHDDFAVISASPELFFKQEKNQITTRPMKGTTKRGYNLELDQQEHDWLQAD
                     PKNRSENMMIVDLLRNDMNKICQTGSVTVTQLCQLEQYSTVWQMTSTIVGMLQDQCRL
                     YDILQALFPCGSITGAPKVSTMAIINRLEPKPRGVYCGSIGICLPDGRRVFNVAIRTI
                     QLSYDQAIYGVGGGITWESCWQDEFEEIKQKSSFLNRQSIDFTIKTTAKVEQQSLIYL
                     DQHLNRLREAARYFAYPYDEELLTDRLQAYLKGKDSSPYRLTIAIAKDGQISLTDQSL
                     EPLQKDFLKARLVRQSSDVKKLPFTYFKTSHRPHLSVKPYEQVFVAADGTLLETSIGN
                     LFVQIEQTLYTPPVSAGILPGIFRQELLRQGLAQEKELKLSDLDKAEAIFGGNAVRGL
                     YSLTIEDTTLPQ"
     gene            3817..4287
                     /locus_tag="TV193_001073"
     CDS             3817..4287
                     /locus_tag="TV193_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEL1513275.1"
                     /translation="MAKYGFLSVLEEEMDKHFHYDYAMDWDKKNHAVEITLVLEAQNQ
                     SAVETIDDQGQLSKEDIVFEDYVLFYNPEKSQFQAADYLVAIPFEPKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKLDFSLEWNEEAFEEGQVGLEETELYSYPRY"
     gene            4289..4633
                     /locus_tag="TV193_001074"
     CDS             4289..4633
                     /locus_tag="TV193_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL1513276.1"
                     /translation="MLHEMMLTPRPFAMIEAGVKTIELRLNDEKRQAIKVGDWICFYC
                     TEDHSHILQAEVVGLHYFDDFAKLYQALPLEKCGYRNEELALARPEDMEQYYSKEQQA
                     QYGVVGIELRLC"
     gene            4650..5078
                     /locus_tag="TV193_001075"
     CDS             4650..5078
                     /locus_tag="TV193_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1513277.1"
                     /translation="MKLLDKTVHFSGAKLALISNGKILTILRDAIPTIPYPNMWDLPG
                     GGRENAEAPFDCASRECYEELGLALTKDAVVWERVYPGLVNPDSQSVFLVALMNQDMI
                     DHIAFGDEGQGYQLMAIDDFLADDRVIPQLKARLADYLRK"
     gene            complement(5276..7813)
                     /locus_tag="TV193_001076"
     CDS             complement(5276..7813)
                     /locus_tag="TV193_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1513278.1"
                     /translation="MKQHQRFLSLVGLLLACNLALTACQTHSQKGHSQEPKKHQKATK
                     KKKQKSSKTAKKRERHQVPGIDVPTDDGFLLTSESQIERKTDTGIIVKHGDHKHFFFY
                     SDLKGTKWAYLIPKDYKEAQPASNQAARSGSVVSTGHAGDGYVFNPADIVAEDAYGYT
                     VRHGDHYHYILKSSLPSATINHIASTTPHFPSTPPSIHQQGGIPGIDFKTSDGFLFDG
                     TNISGVTDTGILVKHGNHLHPISFEDLKRSKWAYLVEQYKKKDHTKPQEGDYRAYIAY
                     LAKELKVDQARIKQVNVDGQVGFEYPHEDHTHVIWLKDIDLSKPFKTPEEQILKKIDG
                     ETFEQRKERLIKEFMDRFKVRREDISIEGNYMTISHGDHAHIYKIDPELPDDPERNVK
                     TESTNLEVETQLVYGPFYTENSSENLTRDGVYKKYHPEGIKNIKNFIHVLFSTNSEYG
                     DIEVNGIKTKRVHYLVRKDLDWKDLNIQRPEAIKHEGRIFKGWSAELPTAGKMDREHQ
                     RFYVDFDKVRKQPTKAVYGPGDDVSDLDLENYVPVWFTTIFNGRLKLNGVTQGGFFYN
                     VRSGLTWKEAKEQGLVIPEPVPDPGYEFIEYRSGVNLANNFNLTDFAKRFSITQNEND
                     KVAFTGLFSAAFGTTAPYIGPYIAVNPDKPTDLEDPSRHPNYYFHDPRHYVAVAFKAG
                     EGGQLISRAGKGKTAVYLVRKGHSLHTAGILPPSVQPDAGYKRDYNKPIISTEEYDKE
                     VTEDIVYNVNFDKITNNDVTGNSNHSGNTWLPGDPLPKEPQTPNHTGSTGSWLEEFVA
                     PVSDSDEDDLLAPDPELVGKTPVSDKPASYFLGESETASSTSVASNS"
     gene            7958..8131
                     /locus_tag="TV193_001077"
     CDS             7958..8131
                     /locus_tag="TV193_001077"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513279.1"
                     /translation="MKGFLAISKAWSFNRRISYWFFWIYEKELLFFDVAGIKYGKIGS
                     IKSLSTFRLAEIC"
     gene            8376..9329
                     /locus_tag="TV193_001078"
     CDS             8376..9329
                     /locus_tag="TV193_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEL1513280.1"
                     /translation="MKAWQELTITVHREAEEAVSNLLIEAGSQGVAINDTADYIGQED
                     RFGELYPAVEQSEMVTITAYYPSSADIDDIRQTINQGLNRLKQCDVELGELTLTNQEL
                     AEEDWADNWKAYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKL
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQ
                     ATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLIKSEGYLIMSGIISEK
                     LDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG"
     gene            9329..10075
                     /locus_tag="TV193_001079"
     CDS             9329..10075
                     /locus_tag="TV193_001079"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEL1513281.1"
                     /translation="MQQYFIKGRAEKIVQLTDKDTIKHMFQVMRLTDKEELVLVFDDG
                     IKRLARVSDSSAYEVELIKELEENLEMPVEVTIASGFPKGDKLDVITQKATELGAAAI
                     WGFPADWSVVKWDSKKLAKKQEKLAKIALGAAEQSKRNRVPEIQLFDQKGELLKQLKQ
                     FDKCFIAYEEAAKAGERSTLARELAGLSPGQKVLFIFGPEGGISSKELASFKQAGAIT
                     VGLGPRIMRTETAPLYALSAVSYALELMSS"
     gene            10324..11328
                     /locus_tag="TV193_001080"
     CDS             10324..11328
                     /locus_tag="TV193_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1513282.1"
                     /translation="MVTIKDVARLAGVSPSTASRAINDSDMISQATKERVKKAMEALD
                     YSPNYSAQNLVKRKSNTVGIILPVREGQDSLGNNPFFMQIIQGIAAVCTDQGYMVALA
                     TGRSEAELLKNVQNMIRSGNIGKLIFLYSKTDDQVFDFVKRQRVDCVVVGQSTTKDPG
                     NAKFVNNNNHQAGYDAAAFLLQKGYEAIVYAYTDMAELVQAERYKGYAELMTSKALAA
                     QALCVTLKDDRKSQKQLLDQLAKRSKVAFVVCDDVLAIHLQRLIKQVAADTQLAIVSF
                     NNSVLAELASPALTSIAIFPYQLGEQAAELVLSSAAPSPQPVLVPHQIIERESTPFIV
                     "
     gene            11625..13811
                     /locus_tag="TV193_001081"
     CDS             11625..13811
                     /locus_tag="TV193_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1513283.1"
                     /translation="MKTSFKQFFSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPML
                     NQESQLLATLGNVIAQVGWAVIGNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAIYGVSSAMLTDPEAKIKSLLGTEMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPDVLAFFNGKRFVPFVVILRSALVALVLALIWPVIQSGINGFGMWIA
                     SSQDTAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVNLKGSNASTYQHLMETVVPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMAIKAGLGMDLINFVWVSILFAVIMYVIADFMIKKMKLATAGR
                     LGNYDADILENDDTKPLSQQSIDGQSQVVQIINLLGGRENIADVDACMTRLRVTVNDP
                     SKVGSEEHWKQAGAMGLIIKGSGIQAVYGPKADILKSDIQDLLDSGAVIPEPKPAQPA
                     ASSSQQTDFKNLTEAVLAVADGEVLPITAVSDQVFAAKMMGDGFAVEPANGAIYAPVT
                     GLVTHVFPTKHAFGLLTDSGLEVLVHVGLDTVDLNGEPFTVKVSEGQRVSAGDLLAEA
                     DLTAITAAGRKTTVVVAFTNTTSIKAVNLVATGQQKAKTLVAQVEL"
     gene            13889..14710
                     /locus_tag="TV193_001082"
     CDS             13889..14710
                     /locus_tag="TV193_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1513284.1"
                     /translation="MTKLLTLNTHSWMEANALKKLFDLAEHILAQNYDVICLQEINQL
                     IDSEAAVSLSGYQPIAGTPAIHQDNFALLLVNYLKKRGQSYYWSWAYNHIGYDIYHEG
                     VAILSKQPIQASDILVSAVADEYDYHTRRALLAKTTIDGREAAVVSLHLSWFDQGFVG
                     EWQRLEAALQQLACPVLLLGDFNNPSGQEGYEMILKSPLDLQDSHQAADYVFGDHSIV
                     AAIDGWEDNKEAFKVDHVFTSKVFTINSSKVTFDGGEAPVVSDHYGLEVDLSWKL"
     gene            complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TV193_001083"
     CDS             complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TV193_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1513285.1"
                     /translation="MTDLTLVFISLSGNTLSFVRRLSQYLAEKHHIQTKAINIKELHH
                     ETFSVKESFVAILPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNAKRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPMLGDFELRGTSADIERLAQVIVARLTDDQQS"
     gene            complement(15860..17044)
                     /gene="sezV"
                     /locus_tag="TV193_001084"
     CDS             complement(15860..17044)
                     /gene="sezV"
                     /locus_tag="TV193_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_038674722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen transcriptional activator SezV"
                     /protein_id="HEL1513286.1"
                     /translation="MDTMSLVKSLQGCLKLSITVFDKDHQVTESFWNDDTFEFYYRFQ
                     AVLRQMDKEQATNLFFQGSYNELFLIYRYQDHYILIGPWRCNVLDKTFFKVAVADKDL
                     TKEEEEILYQALKHLPVYPLNAIRDLLIVVHYFFSGKIEDLLSPPLRHYIRDFSDNIE
                     VQKANMFVKKQESKVCLYNYEKNLSSIVQEGDVHKLKEIIFSLRNTFIPVVSGDTLRS
                     EKNYSIIAFDRLAQIAIQSGMDIADAYHSREEFMRDSELATSMPDVLKIRDASLVFYT
                     QKVSELRDNRWKHVSPTVNAIIQYISVNLHKSVTTAELAQHFNMSESKLRQIFKRDTG
                     LTIYQYTSNMKIEEAKTLLRSAYAINHISDVLGFTDPSHFSKFFKKHTGESPKTYQNR
                     KH"
BASE COUNT         4570 a         3515 c         4076 g         4943 t
ORIGIN      
        1 cttgtttttt tctttaggct agctgctaga aagcttatca attcgcgctt tattggcggc
       61 taaggctctt tcatattttc ctgtttcatt tgggttgaag taatttttct taaccaagtg
      121 atcagggaga tattgctgct tgacccattt ttctggatat gcatgagggt aaaggtagtg
      181 ctgagcattg cctagctcct tgctgccggc ataatgccca tcacgcaggt gtctaggaat
      241 gggaagatgg ccatgttgac gtaaatcagc gagagcagcg tccatagcca tataggcgga
      301 attggacttt ggtgacagtg ctagatcaat cacaacattg gcaatgagga tacgcgcctc
      361 tgggaagcca attttctggg cggcctcaag tgcagtgacg gtatggattt gagcttctgg
      421 attggcaaga cctatgtcct cataggcgat aatggtcaag cgtctagcaa gactcggaag
      481 atcgcctgcc tcaataagcc ttgcagcata gtgcaagcta gcattaacat cagatcctcg
      541 gattgatttt tgcaaggcag atagtatgtc ataatgtccg tcgccatctt tgtccattgt
      601 gatgtagctg cgctgcaaag aattttcaac agtattcaag ctgatatgac ggataccctc
      661 ggtatctggc tgggttgaca tgacagctag atcaagggat tggtaggcgg ctcggagatc
      721 tccatttgtc gctgtcgcaa taaagtcaaa agcagcctca tctagggtca catcaaaggc
      781 aaagcctctc tccttatcag tgatggcaag cttaagcgcc tgcttgatct cctcaggtga
      841 taggggctcc agctcaaaaa tctggactcg acttctgatg gctggagtaa ccgagaaaaa
      901 aggattccct gtggtagcac caatcataat aatgtgccca tgctctaaaa gtggtagtaa
      961 aaagtcctgc ttactcttat ccaatcggtg aatttcatca agcaaaagca caagtccacc
     1021 tgaaaactta gcttcctcag cgatttcttg gaggcgtttt ttattgtcta tggtagcatt
     1081 gaaggttcta aaggcgtact tggttgttcc agcaatagca ctagcaattg atgtctttcc
     1141 aataccggga ggtccgtaaa gaatcattga ggctaatcta ttggccttga ccatgcggtc
     1201 aatgattttt ccctccccga ccagatgctg ctggccgatg acctctgtaa tggttctagg
     1261 gcgcattctg atggctagat tatcaggcat tgtattcctc ccttccttgc ttttgttggc
     1321 tgtggtgctt tttaacaaca gccataaagt ttgcgatcat tgtcctaccg tcagctgttc
     1381 cgatgctttc tgggtgaaat tgaaggccaa acagtggcag ctgtctgtgt tcaaaggcca
     1441 taatctcatt gtcctcaaag tctcttgcgg taattacaaa gtcagctggc aggtcatcaa
     1501 caacaataga atggtaacgc atgacggtta attgctttgg cagctgttga aagagcttag
     1561 ctggtgcttg tctttcaagt atactttgct tgccatgcat gacgcgctta gcaaggcgta
     1621 gcctgccacc tagagcctca gcgatagctt ggtggccaag gcaaacgcca agcataggct
     1681 tttggtcata aaaggcccta atcaagctag gcatctgatt ggcggctttg ggccagccgg
     1741 gtccaggtga gaggactatg gcgtcagcct gcttcgcaag gtcaaatagt tttggatcct
     1801 gattggtcaa tacaatcgtt tgatcaaagg cactgaggta ttgggccaga ttataggtaa
     1861 atgaatcgta gttatcaatt aaaagtatca taaggtcctt catctagtag tgctgaggga
     1921 tcagcctggt actattgagg cagagtggtg tcctcaattg ttagtgagta gagtcctcgg
     1981 acagcattgc caccaaaaat ggcttcggcc ttgtctaaat ctgaaagctt tagctctttt
     2041 tcctgagcca gtccctgcct tagtaattct tgacggaaaa tgcctggtag aataccggct
     2101 gatacaggcg gtgtataaag ggtctgctcg atttgcacaa aaagattacc aatagaggtt
     2161 tcaagcaagg tcccatcagc agcaacaaag acttgctcat aaggcttgac gctcagatgt
     2221 ggtcgatgac tggttttaaa ataagtaaag ggaagctttt tgacatcgct tgattggcga
     2281 actaatcgtg cctttaaaaa gtctttttga agcggctcta agctttggtc tgtaaggcta
     2341 atctgcccgt ccttagcaat agcaatagtg agacgatagg ggctgctgtc ctttcccttg
     2401 agataggctt gcaaacgatc tgtcagaagc tcttcgtcat aggggtaggc aaaataacgc
     2461 gccgcctccc ttagtctgtt gaggtgctgg tctagatata ttaggctttg ttgttcgacc
     2521 ttggcagtgg ttttgatggt gaaatcaatg ctttgacggt tcagaaagga agatttttgc
     2581 ttgatttctt caaattcgtc ctgccagcag ctttcccagg taatcccacc gcctaccccg
     2641 tagatggcct gatcgtagct gagctgaatc gttcgaatag cgacattgaa gacacgtctg
     2701 ccatcaggca ggcaaatacc aatgctgcca cagtaaacgc cccttggctt aggctctaat
     2761 cggttaataa tagccattgt agacacctta ggagctcctg tgatggagcc acagggaaag
     2821 agtgcctgta aaatatcata aagacgacac tgatcctgca gcatgccgac aatggtagag
     2881 gtcatctgcc aaacggtgga atattgctcc aattggcaga gctgtgtgac tgtgacactc
     2941 ccagtttgac agatcttatt catatcattg cgtaataaat caacgatcat catgttttct
     3001 gaacggttct taggatcggc ctgtagccag tcatgctctt gttgatctag ttctaaattg
     3061 taaccacgct tggttgtgcc tttcatgggg cgtgtggtga tctggttttt ctcttgcttg
     3121 aaaaataact caggactggc tgaaatgaca gcaaagtcat cgtgagcaat gtaggcattg
     3181 tatccagctg cctgttcaat gaccaattga tgataaatgg ccaagctgtc cttagcgttt
     3241 agcctttggc tgagctgaat ggtatagttg acctgatagg tattgccctg cctcatctcc
     3301 tgatgaatct gtgcaatagc ctcttgatag gcttcctctt gtgtagcact tgtccagctg
     3361 tttggaatcg tcatgctgtc gtggtagagc ggaaagtcct cgagctgaca gctgtcatgc
     3421 actgtaaaat aagcaaaata ttcctgacca agtcttttat tgtgtgttgt tagctttttg
     3481 tcaaaacagg ctgctgcttc atagctgagg tagcccacaa catagtagcc cagatcttga
     3541 aattggttga cctgctcaag gacctgtccc acctgatcaa tctgcttagc tactaattcc
     3601 acgataggag cttgaaatat atagcgttgt cccagctcct taaaatcaat aatcgtcttt
     3661 atatgcatag cttgattata tcataaatgc gcttttcaga ctgattagga gggttgaaaa
     3721 gaagcctgtt agcaaccatc aacaatacaa gagagcaggg cttcttgatt tatgctacaa
     3781 tagtagcgga tattatttag aaaaaggaac aagagcatgg ctaaatatgg ctttttatca
     3841 gtattagaag aagagatgga caagcatttt cattatgact atgctatgga ttgggacaag
     3901 aaaaatcatg cggttgaaat cacccttgtt ttagaggctc aaaatcagtc agcagttgaa
     3961 accattgatg accaaggaca gctcagcaag gaagacattg tctttgagga ttatgtctta
     4021 ttttacaatc cggagaaatc acagtttcaa gcagcagact atctggtggc tattccattt
     4081 gagccaaaaa agggcttttc tcgtgaattt ttagcctatt ttgcccagtt tctcaatgat
     4141 gttgccattg aagggcatag cgatttgatg gatttcttag cagatgatag caagcttgat
     4201 tttagtctag agtggaacga ggaggccttt gaggaagggc aggtaggact agaggaaaca
     4261 gagctttata gctatccgag gtattaagat gctacatgag atgatgctga caccaagacc
     4321 atttgctatg attgaggcgg gtgtgaagac tattgaacta cggttaaatg atgagaaaag
     4381 gcaggctatt aaggtagggg attggatttg cttttattgt acagaggatc atagccatat
     4441 tctgcaagca gaggtcgtag ggttgcatta ttttgatgac tttgctaagc tttaccaagc
     4501 attgccttta gaaaaatgtg gttatcgtaa tgaagaattg gcactggctc ggccggagga
     4561 tatggaacag tactacagca aagagcagca agcccaatat ggcgttgttg gtattgagct
     4621 aaggctatgt tgattggtga gatctagtca tgaagctttt agataaaaca gtccattttt
     4681 ctggtgcaaa gttagccttg atcagtaacg gtaagatttt gaccatcttg cgtgacgcga
     4741 taccaacgat tccttaccct aatatgtggg atttaccagg aggtggtcgt gaaaatgctg
     4801 aagctccctt tgattgtgcg tcacgtgagt gctatgagga gttaggtctg gcactgacta
     4861 aggacgctgt cgtttgggaa agggtttatc cagggcttgt taatcctgac agccaatctg
     4921 tctttctggt ggctcttatg aatcaggaca tgatagatca tattgctttt ggtgatgagg
     4981 ggcagggtta tcagctgatg gctattgatg actttttagc agacgatcgg gtcattcctc
     5041 agctaaaggc tcgcttagct gattatttaa ggaaataggc agacttagct ggtacactaa
     5101 acagatcagc aaacaccact actatgtgat agctacgacc agaatcaaaa agacgattga
     5161 cctctgccca catgtggcta ggatcaatcg tctttgtttt tggggtggct aagtctttaa
     5221 tctggtaggc cagatcagct gagtagttga tattatcaat cagtcctgct atggcttagc
     5281 tgttgctagc tactgatgtg ctgctagctg tctctgactc acctaaaaaa tagctggctg
     5341 gcttatcact tactggcgtc ttaccaacaa gctcagggtc aggtgctaat aggtcgtcct
     5401 cgtcggagtc agaaacgggc gctacaaatt cttctagcca gcttccagtg ctgccagtgt
     5461 gattaggagt ttgaggctcc ttaggtagtg gatcacctgg tagccaggta ttccctgagt
     5521 gattactatt acctgtaaca tcgttgttgg ttattttatc aaagttgacg ttataaacaa
     5581 tatcctcagt gacttcctta tcatattcct cagttgaaat aataggctta ttgtaatcac
     5641 gcttgtagcc ggcatctggc tgtactgatg gtggtaggat accagctgta tgtaatgagt
     5701 gtcccttacg aacaaggtaa acggcagtct tacccttacc agctcggcta atcagctgtc
     5761 cgccctctcc tgccttaaag gcaacggcta catagtgtct cggatcgtgg aagtaataat
     5821 tagggtgtct gctaggatcc tctagatcag ttggcttgtc aggattaaca gcgatgtaag
     5881 gtccaatata aggagcagta gttccaaagg ctgctgagaa taggccagta aaggctacct
     5941 tatcgttttc attttgtgtg atagaaaatc tcttagcaaa atcagttaga ttaaagttat
     6001 tggcaaggtt cactccactg cggtattcaa taaattcata gcctggatct gggacgggct
     6061 cagggataac aagtccttgc tccttagctt ccttccaggt aagaccacta cgaacattgt
     6121 agaagaagcc tccttgagtc acgccgttaa gcttcaatcg cccattaaag attgtggtga
     6181 accagacagg aacataattt tctaagtcaa ggtctgaaac atcatcacct ggcccgtaga
     6241 cagccttggt aggctgcttt ctaaccttat caaaatctac atagaagcgt tgatgttctc
     6301 tgtccatctt gccagctgtt ggcaactcag cactccagcc cttaaagata cgcccctcat
     6361 gcttgattgc ctctggacgc tgaatgttca aatccttcca gtccaaatcc ttacgaacca
     6421 aatagtgcac acgtttagtt ttaatgccat taacctcaat gtcgccgtat tcactatttg
     6481 tactaaacaa cacatggata aagtttttga tgtttttgat gccctctggg tgatattttt
     6541 tatagacccc atcacgtgtt agattttcag atgaattttc cgtatagaaa ggaccataaa
     6601 cgagctgagt ttcgacctct agattggttg attctgtctt gacattgcgc tcaggatcat
     6661 ctggcaattc tgggtcaatc ttatagatgt gagcatggtc cccatgacta atggtcatgt
     6721 agttgccctc aattgagatg tcctcacgac gaaccttgaa gcgatccata aattctttga
     6781 tgagtctttc tttgcgctgt tcaaaggttt ctccgtctat ctttttgagg atctgttctt
     6841 ctggagtttt aaatggctta gaaagatcaa tatcctttag ccagatgacg tgcgtgtggt
     6901 cctcatgagg gtattcaaag ccgacctgac cgtctacatt cacctgctta atgcgtgctt
     6961 gatctacctt tagctccttg gcgagataag ctatataggc gcgatagtct ccttcctgag
     7021 gcttggtgtg gtcctttttc ttatattgct ccactaaata agcccatttg ctacgcttta
     7081 agtcctcaaa gctaataggg tgcaaatggt tcccatgctt caccaggatt ccagtgtcag
     7141 tgacaccgct aatgttggtg ccatcaaata agaagccatc actagttttg aagtcaattc
     7201 ctgggatacc cccctgctga tgaatgctag gtggtgttga tgggaagtga ggtgtggttg
     7261 atgcgatgtg gttgatggtt gctgatggca ggcttgattt gaggatatag tggtaatgat
     7321 ctccatgacg aacagtgtag ccataggcgt cctcagcaac aatgtcagct ggattaaaga
     7381 catagccgtc tccagcatga ccagttgaga ctactgatcc agaccttgcc gcttggttag
     7441 aagcaggctg tgcttccttg taatccttag gaatcaggta agcccatttt gtccccttca
     7501 aatctgagta aaagaagaaa tgcttgtgat cgccatgctt cacaatgata cctgtatctg
     7561 ttttgcgttc aatttgcgat tcgctggtca ataaaaagcc atcatcagtt gggacatcaa
     7621 tcccagggac ttggtgacgt tctctttttt tcgcagtctt actgcttttt tgttttttct
     7681 ttttcgtagc cttttggtgc tttttaggct cctgagaatg tcccttttgc gaatgcgttt
     7741 ggcaggctgt taaggcaagg ttgcaggcta acagcagtcc aacgagggat aaaaatcgtt
     7801 gatgttgttt catggttagt tatcaactcc ttccaacaat taacttaacc agttaatatt
     7861 attactggtt aagtatatca tttgacatct aagaatacaa tagattttat aaatttttta
     7921 atgaaattaa tctaatgacc taagagctgt ctggaagatg aaaggctttt tagctatttc
     7981 aaaggcttgg agcttcaaca ggcgaatcag ctattggttt ttctggattt acgagaaaga
     8041 gctgctcttt tttgatgtag ctggtataaa atatggtaaa atagggtcta tcaagagcct
     8101 atctaccttt agattggctg agatttgtta ggcaatgcgt ccctgataaa ggttgggctt
     8161 atgggacaat aggccttggt gctgtgtttg tccttagtat gaaacctctg agacggcaga
     8221 gcaggatccg gttggtttag gaccgcatta gcttatctta cgataaaaaa gaagcttgaa
     8281 aggaaaggct gctttgatct gatagagggt cactggtttt agggtttagg ctaggggcaa
     8341 gtgaccactg atgatatggc agcaagggta tcgttatgaa ggcatggcaa gagctgacaa
     8401 ttacagtcca tcgtgaggca gaagaagctg tttccaatct gctgattgag gctggcagcc
     8461 aaggagtcgc tatcaatgac actgcagact atatcggtca agaggaccgt tttggggagc
     8521 tttatccagc tgttgagcag tcagaaatgg ttactattac agcctattat ccaagctcag
     8581 ctgatattga tgacatcaga cagaccatta atcagggctt gaacaggcta aagcagtgtg
     8641 atgtggagct tggtgagtta accctgacca atcaagaatt ggctgaagag gattgggcgg
     8701 acaactggaa agcctattat gagcctgctc gtatcacgca tgatttgacg atagtcccca
     8761 gttggacaga ttatgaagcc acagcaggtg agaagatcat taggcttgat ccgggtatgg
     8821 catttggaac aggcacacac ccaacaacta agctaagcct gtttgccttg gagcaggtgc
     8881 ttcgtggtgg tgagacagtt attgatgtgg ggacaggctc aggtgtgcta tcgattgcta
     8941 gctctctgct tggcgccaaa gaggtctttg cttatgattt agatgatgtg gcggtgcgtg
     9001 ttgccaaaga caacattgcc ctcaatcaag ccactgacaa tatccatgta gcagctggag
     9061 acctgctaaa aggccttact caagaggcag acgttattgt cgccaatatc ttggcggata
     9121 ttttggtgca tgtgacagca gatgcttacc gtcttatcaa gtctgagggg tatctgatca
     9181 tgtcagggat tatttcagaa aagctggata tggtgaagca ggctgctctt aatgcaggct
     9241 tcttgctaga gactcacatg cttcagggcg agtggaatgc tcttattttc aaaaaaacag
     9301 atgatttatc aggagtgatt ggtggctgat gcagcagtat tttattaaag gcagggcaga
     9361 aaaaatcgtt cagctgaccg ataaggatac cattaagcat atgtttcaag tgatgcgctt
     9421 gacggataag gaagagctgg tgctagtctt tgatgacggc attaaacgct tggcaagggt
     9481 gtcagacagc tcagcctatg aggtggagct tatcaaagag ctggaagaaa accttgaaat
     9541 gcctgttgag gtgactattg cctcaggctt tcccaagggt gataagctag atgttatcac
     9601 tcaaaaggcg actgagttag gggcagcagc tatttggggc tttccagcag actggtcggt
     9661 ggtcaagtgg gatagcaaga agctagctaa aaagcaagaa aaattagcta aaattgctct
     9721 tggagcagca gagcaatcca agcgtaatcg cgtaccggag attcaactat ttgaccaaaa
     9781 gggtgagcta ttaaagcagc ttaagcagtt tgataagtgc tttatcgctt atgaggaagc
     9841 agctaaggca ggtgaaaggt cgacattggc gcgtgagcta gcaggtctta gcccaggtca
     9901 aaaagtcctc tttatctttg gaccagaggg tggtatttct tcaaaagagc tggctagctt
     9961 taagcaagca ggtgctatta ctgtgggact ggggcctcgt atcatgcgga cagaaacagc
    10021 accgctctat gccttgagtg ctgttagcta tgctctggag ctaatgtcta gctgatagtg
    10081 ctaataggag acagcacctt gtggctcagt gcttgacaga aaaaagagga gcatctgcga
    10141 ttatgctaat aaagcaccgc ttaacaaaaa gatcgctaag aaggagactg ccgcaaatca
    10201 aagggctagt ctagcccgcg taggtgcaga gctgtcgggc ctttgcagct tcatttgtaa
    10261 aaaatataac aaatcatctc aaaataaaga tactcgtcaa acggattggt agaggaggga
    10321 catgtggtta cgataaaaga tgtggcaagg ctagcaggag tttcgccttc aacagcttcg
    10381 cgtgccatca atgacagtga catgattagt caggcgacaa aggagcgtgt caaaaaagcc
    10441 atggaggcct tggattattc gcctaattat tcggcgcaaa accttgttaa gcgaaagtcc
    10501 aatactgtcg ggatcatttt gccggtgcgt gagggtcagg attcactggg aaataaccct
    10561 tttttcatgc agattattca aggaattgct gctgtttgta ccgatcaggg ctacatggta
    10621 gcccttgcga ctggacgtag tgaggccgaa ttgctaaaaa acgtgcaaaa catgatccgt
    10681 agtggcaata ttggcaagct gatttttctt tattccaaaa cagatgatca ggtttttgac
    10741 tttgtcaaaa ggcaaagagt ggattgtgtt gtcgttgggc aatcaacgac aaaggatcct
    10801 ggcaatgcta aatttgtcaa caacaataac catcaagccg gctatgatgc agcagcattt
    10861 ctccttcaaa aaggctatga ggctattgtc tatgcttata ctgacatggc cgaattggtg
    10921 caggcagagc gttataaggg ctatgcagag ctgatgactt caaaggctct ggcagctcaa
    10981 gccctttgtg tcacgctaaa ggacgatagg aaaagtcaaa agcagctgtt agaccaatta
    11041 gccaagcgct ctaaagttgc ctttgtagtc tgtgatgatg tgctagctat tcatttgcag
    11101 cgtctcatca agcaagtagc agctgacacc cagctagcaa tcgttagctt caataattct
    11161 gtcctagcgg agcttgcgag tcctgccttg acctccattg ctatttttcc ctatcagctg
    11221 ggagagcaag ctgctgagct ggtcttatca agcgcagcgc catcaccaca gccagtctta
    11281 gttcctcatc agatcattga aagagagtct acgcctttta ttgtttgatt taccgttaag
    11341 cctattccta agcaaagtac tgatagcttg cttaggaata aggcttttta tttaggaatt
    11401 tattttgttt gctaatagta ttaaagagaa gcaacgttta ctttagcatt ttcattgaaa
    11461 tcttcttaag aaaacgcttt acaaaacaaa aaaaggttgg taaaataagc ttatcaaaag
    11521 cgcaaacgtt tgcgttgaat gtgcttgttt ttaaaaagga attgagagtt catcagcttt
    11581 tagctggtta ttcttgattc ctagtccaaa aaaggagagg tcgaatgaaa acatcattca
    11641 aacaattttt tagcttcgag ttttggcaaa aattcgggaa atgcttgatg gttgtcattg
    11701 ctgttatgcc tgctgcaggt ttaatggtga gtattggaaa ttctctgccc atgcttaatc
    11761 aggagtcgca gcttttagcg acgcttggta atgtcattgc tcaggttggt tgggcagtta
    11821 ttggtaacct tcatttgctt tttgcccttg ctattggtgg cagctgggct aaggagcgtg
    11881 ctggcggtgc ctttgcttca gggcttgctt ttgttttgat taaccgtatt acaggggcta
    11941 tctatggcgt ttcttcagcc atgctgactg atccagaggc caagattaaa agtcttttgg
    12001 gcactgagat gattgtcaag gactacttta caagcgtctt agagtcacct gctctaaata
    12061 ccggtgtctt tgttgggatt atcgctggct ttgtgggtgc aacagcctat aacaaatact
    12121 acaattaccg taagctgcct gatgtgctgg ctttctttaa tgggaaacgc tttgttcctt
    12181 ttgtagttat ccttcgttca gctcttgtgg ccctagtatt agccttgatt tggccagtta
    12241 ttcagtctgg tattaatggc tttggcatgt ggattgcctc atctcaggac acagctccaa
    12301 tccttgcgcc attcttatat ggaacattgg agcgtctctt gctgccattt ggccttcacc
    12361 acatgctaac gattccgatg aactatacag ctcttggggg cacctatgag gtcatgacag
    12421 gagcagctgc tggaactaag gtatttggtc aagaccctct ttggctagcc tgggttactg
    12481 accttgttaa tctcaagggc tctaatgcgt caacctatca gcatttgatg gagactgttg
    12541 ttccggctcg ttttaaggtt gggcaaatga ttggtgcaac aggaacgctt atgggggttg
    12601 ccctagcaat gtaccgtaat gttgatgcgg acaaaaagca taaatacaaa atgatgttta
    12661 tctcagcagc ggcagcggta tttttgacag gggtcactga gccactggaa tacatgttta
    12721 tgtttgctgc gatgccatta tatcttgtct atgcccttgt tcaaggagct tcctttgcaa
    12781 tggctgattt ggtcaacctt cgtgtgcatt cctttggtaa tatcgagcta ttgacccgaa
    12841 cgcctatggc gattaaggct gggcttggta tggatttgat taattttgtc tgggtgtcta
    12901 ttctgtttgc tgtgatcatg tatgtcattg ctgactttat gattaaaaaa atgaagctag
    12961 caacagcagg tcgcctaggg aattacgatg ctgatatact agaaaacgat gatacaaagc
    13021 ctttgtcaca gcagtctatt gatggtcagt cacaggtcgt ccaaatcatt aatctcctgg
    13081 gtggacgtga gaatattgct gatgtagatg cttgtatgac tcgcttgcgt gtaacagtca
    13141 atgacccaag caaggttggc agtgaggagc attggaagca ggcgggtgct atggggctaa
    13201 tcatcaaggg cagtggtatt caggctgtct atgggccaaa ggctgatatt ttaaaatcag
    13261 atatccaaga cctgctagac tctggtgcag tcattccaga gccgaagcct gctcagcctg
    13321 ctgcctcatc atcacagcag acggacttta aaaacctaac agaggctgtt ttggcagtag
    13381 cagatggaga agtcttgcca atcacagcag tttctgatca ggtctttgca gctaaaatga
    13441 tgggagatgg ctttgctgtt gagccggcaa atggcgctat ctatgcgccg gtaacaggtc
    13501 tggtaaccca tgtctttcca accaaacatg cctttggctt gctgacagat agcggcctag
    13561 aggtgctggt tcacgttggt cttgataccg ttgacttgaa tggtgagccc ttcactgtca
    13621 aggttagtga gggtcagcgc gtatcggcag gagatctctt ggctgaggct gacctaactg
    13681 cgattacagc agcaggacgc aagacaacgg ttgttgtcgc ctttaccaat actacaagca
    13741 tcaaagctgt taaccttgtt gcgactggtc aacaaaaagc gaagaccctc gttgcacagg
    13801 tagagcttta agaataacca aagagagtgg tagatagcag tatgtcagac ctgcaggctg
    13861 ccacttctct tgtcgtatag gagaagatat gaccaagctc ttaaccctta acacacattc
    13921 ttggatggaa gccaatgcct taaaaaagct gttcgacttg gcagagcata ttttggctca
    13981 gaactatgac gtgatttgcc tacaagaaat caatcagctg attgacagcg aagcagcagt
    14041 gtcattatca ggctaccagc caattgcagg gacacctgcc attcatcagg ataactttgc
    14101 cctcttgctt gtcaattact taaaaaaacg tggccaaagc tactactggt cgtgggccta
    14161 caatcatatt ggctatgata tttaccatga gggtgttgcg atcttatcca agcagccgat
    14221 ccaagcctca gacattttag tctcagcggt ggctgacgag tatgattacc acaccagacg
    14281 ggctttactg gccaaaacaa ccattgatgg cagggaggca gcagttgtga gcctgcattt
    14341 gtcttggttt gatcagggct ttgtcggaga atggcagcga ttagaggcag ccctgcagca
    14401 gctagcctgt cctgtgctat tgctgggaga ttttaacaat ccaagtggcc aagagggcta
    14461 tgagatgatt ctaaaaagcc ccttagacct tcaggatagt catcaggctg cagactacgt
    14521 ctttggagac catagtattg ttgctgctat tgatggctgg gaggataaca aagaggcctt
    14581 taaggtcgac catgtcttta ccagtaaggt ctttaccatt aacagctcaa aggtgacctt
    14641 tgatggtggt gaagcaccgg ttgtcagcga ccattatggc ctagaggttg acctcagctg
    14701 gaagctgtaa caaaaaaagc cagcaggact tgatagactg ctgacactgt aagaaacaga
    14761 tggttatctt agctcttaga agtaagctta tcgcaaggct tctaagagct tttttgcatt
    14821 tatatttcat gagcatatga gaaagttgca gacaaatgct ggacacataa tcagactgtg
    14881 ggctagttac atcgtctgct ctgatttgtg tcagatagtg atgatctgtg ctgccttgtg
    14941 attggccaga tatttacctc atatcaatag cagaaagtca agtctccctc agcctatctc
    15001 ctagcttacg attgctgatc atcagtcagt ctagctacaa ttacctgtgc caagcgctca
    15061 atatcagcac tggtcccgcg tagttcgaaa tctcccagca ttggaaagcc aaagcgctta
    15121 gcatactgct tggctgttag acaatactgg tgattgaagt ttttgttgcc agagccgata
    15181 atccctaaac aacgcttggc attatcatgc gccgcgataa agtctcccag cggattggtc
    15241 aagatttcaa cctcccctga gtcaatcccg tttcctcctt caagataggt cggcaaaata
    15301 gcaacaaagc tctccttgac tgaaaaggtt tcgtgatgaa gctccttgat attgattgct
    15361 ttagtctgta tgtggtgctt ttctgccagg tattgcgaca agcgcctaac aaagctcagg
    15421 gtattgccgc taagactgat aaaaacaagg gtcaagtctg tcataaaaga ctcctttagc
    15481 aagattagtt tcctaaccag cttagcacaa tacccctgaa tacacaactc atatgacaat
    15541 gctctgcacg acaaacgcgc gaaacagtca tttccgaatg atagtataga cttaagcaga
    15601 tacattcacc gttttttcta tagtaaaagc tatagaaaat aagatatctt cttgaaatag
    15661 ctaaacattg acatacagaa agctttgttt tcttgctaaa accctatcat gcgtctgccg
    15721 tgcaatgctc tgacagctag cccactagtc acatcacata aaaaaggctt ggtgacaagg
    15781 acggtaagtc caaatcatca agtcttttta tggagagagc ttagtgttag ctgttacccg
    15841 aatcaagagg cccttgctgc taatgcttgc gattttgata ggtctttggg ctttctccgg
    15901 tatgcttttt gaaaaattta gaaaaatgtg agggatcagt gaagcccaac acgtctgaaa
    15961 tgtgattaat ggcataagca gagcgcagca atgtcttagc ctcttcaatt ttcatgtttg
    16021 aggtgtattg gtagatggtc aagcctgtat cacgcttaaa gatctgtctc agcttggact
    16081 cgctcatgtt aaaatgctgt gccagctcag cggttgtgac actcttatgc aggttgacac
    16141 tgatatattg gataatggca ttaaccgtag gagagacatg tttccagcgg ttgtcccgca
    16201 gctcactcac cttttgggtg taaaagacca gtgaggcatc acgaattttg agcacatctg
    16261 gcattgaggt tgccagctcg ctgtctctca tgaactcctc tcgtgaatgg taggcatcag
    16321 caatatccat accagattga atggcaatct gggctagtcg atcaaaggca atgatagaat
    16381 aatttttttc agagcgcagc gtatcaccac tcaccacagg gataaaggta tttcgtagac
    16441 tgaagatgat ttccttgagc ttgtgcacat caccctcttg aacaatgcta gataaatttt
    16501 tctcataatt gtagagacaa accttagatt cctgcttctt gacaaacata ttggcctttt
    16561 gcacctcgat attgtcggaa aaatccctaa tatagtgacg taaaggaggt gataacaaat
    16621 cctctatctt gccggaaaag aagtaatgga ccacaatcaa gaggtcacga atagcattca
    16681 aaggataaac aggtaaatgc tttagcgctt ggtaaagaat ctcttcttct tccttagtca
    16741 aatccttatc agcaacggcc accttaaaaa aggtcttatc caaaacatta cagcgccaag
    16801 ggccaattaa aatataatga tcctgataac ggtatattaa aaaaagctca ttatagcttc
    16861 cctgaaagaa aagattggtt gcctgttcct tgtccatttg cctaagcact gcttgaaaac
    16921 gataataaaa ttcaaaggta tcatcattcc aaaagctttc tgtcacctga tggtccttat
    16981 caaatactgt aattgataac ttcaaacagc cctgtagaga ttttactaac gacatagtat
    17041 ccatgctaag cgtcaccccc ttcataatcc tcacggtatc ttattctatc ttaaaattta
    17101 agaa
//
LOCUS       DARYXS010000040        17082 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.041, whole genome shotgun sequence.
ACCESSION   DARYXS010000040 DARYXS010000000
VERSION     DARYXS010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17082
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.041"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(22..993)
                     /locus_tag="TV193_001085"
     CDS             complement(22..993)
                     /locus_tag="TV193_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEL1513287.1"
                     /translation="MTYQKKLIAASMALASVFMLQTVHAAANNVQQVIDETYVQPDYV
                     LGYSLSAEQREQTLALLHYNSASDNKLSTLNTTAYASIMNVADDPSLQLYSSVRIQKL
                     GAKETLKVTIVTPENITKVTQDMYRNAAVTLGIEHANITVAAPIPVTGESALAGIYYS
                     LEKNGAKVPEENKKLAQEELSTLSNINTENAGKTGYDADKLNVALTDIKAAVAKAGEG
                     VNEEKVRQIVTETLDHYGLTKAVTPDQINLIINFALNLSNSGVISNENFTKTLNALKD
                     SIVEKAGSTFKNINVNFDATEALKTGQGILQQIIDFFRGLIDSLMGN"
     gene            complement(1306..1746)
                     /locus_tag="TV193_001086"
     CDS             complement(1306..1746)
                     /locus_tag="TV193_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1513288.1"
                     /translation="MTKKAYLSLFTILLLFPLSACDFKAQDSTGKKLKSSHQLEKRCK
                     ALKKETDKSPNEVSKEEGIAAEQIIVSISDDGFVTSHGDHYHFYNGEVPYDSLFSSEL
                     LPPKDYQFDQKDVINEVKNGYVIKTDDHYYFYLKDNNHQENLRS"
     gene            complement(1743..2678)
                     /locus_tag="TV193_001087"
     CDS             complement(1743..2678)
                     /locus_tag="TV193_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1513289.1"
                     /translation="MIRGFKKTIVAVGLLAVLLGLSACHQSSSSRKAGLVIKTSFYPI
                     YAMTKEICGDLNDVQVIAQNTSIHSYEPSPTVVAKVYDGDVFIYHSKILEAWAADLAP
                     QLEKKGLAVMEGTSHLTLDKVQGLEHFTIKKGMNTDALYDPHTWTDPILASQEAEQIA
                     ALLSQKDPAHKAVYLQNAKRFKAKAQKLVKTYKEKFESLGRKTFVTQHTAFSYLAKRF
                     DLKQLGIAGISPEQEPSPRQLAQIDRFIKKYDVKTIFVEENASDKLAKTLAQSNGVAI
                     DILSPLEVVPADQKTYLEHLKMNLETLYRVLESET"
     gene            complement(3116..3529)
                     /locus_tag="TV193_001088"
     CDS             complement(3116..3529)
                     /locus_tag="TV193_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEL1513290.1"
                     /translation="MELKAIHHIAIIVSDYEVSKDFYVNKLGFEIIRENHRPDRHDYK
                     LDLKCGAIELEIFGNKKTDPAYQAPPKRIGRPEYDKEACGLRHLAFHVKPIEAYIEQL
                     MAKGIAVEPLRYDDYTGKKMTFFFDPDGLPLELHE"
     gene            complement(3627..4382)
                     /locus_tag="TV193_001089"
     CDS             complement(3627..4382)
                     /locus_tag="TV193_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEL1513291.1"
                     /translation="MAKRTHRRRQKRRKMSFARGILVVLLLIIGLALLFNKPIRNTLI
                     AWNSNKYQVTKVSKKTIKKNKEAKSSFDFQAVQPVSTESVLQAQMDAQQLPVIGGIAI
                     PELGINLPIFKGLGNTELIYGAGTMKEDQVMGGENNYSLASHHIFGLTGSSEMLFSPL
                     ERAKEGMSIYLTDKERIYEYEINAVFTVTPERIDVINDTPGLKEVTLVTCTDYEATER
                     IIVKGAIKNEYEFNKAPDDVLKAFNHSYNQMST"
     gene            complement(4387..6882)
                     /gene="gyrA"
                     /locus_tag="TV193_001090"
     CDS             complement(4387..6882)
                     /gene="gyrA"
                     /locus_tag="TV193_001090"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEL1513292.1"
                     /translation="MQDKHLVDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLKDINKNTVDFQDNYDGNEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAEAIDAVKMVMENPDCTTRDLMEVLPGPDFPTG
                     ALVMGRSGIHKAYETGKGSIVLRSRTEIETTSTGRERIVVTEFPYGINKTKVHEHIVR
                     LAQEKRIEGITAVRDESSRQGVRFVIEVRRDASANVILNNLFKLTSLQTNFSFNMLAI
                     EGGIPKILSLRQIIDNYILHQKDVITRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDIIAQAELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILARPERIEAIIKEEMEEIKRKYANPRRTELMIGEVLSLEDEDLIEEEDVLITLS
                     NNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRAAKGLPVINLLKLDDGETIQTIINAKKEDILDKYFFFTTKQGIVKRTE
                     VSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRS
                     ATGVRGVKLREEDWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTAN
                     ITAKNGQLAGLMTVDGSEDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTDSKI
                     VTFTLVQAEDNDPTAIAQTDTALTEAPINSSKE"
     gene            7074..8057
                     /locus_tag="TV193_001091"
     CDS             7074..8057
                     /locus_tag="TV193_001091"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEL1513293.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKTIIDEAFSKEEFASAAKN"
     gene            complement(8262..9629)
                     /locus_tag="TV193_001092"
     CDS             complement(8262..9629)
                     /locus_tag="TV193_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEL1513294.1"
                     /translation="MSKIVVIGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQISGPEGLFYSNKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKEHVE
                     SYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVISKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVADTCLAGYYDRDLTDVMSKNLEEHGIQ
                     LAFGETVKEVAGDGKVEKLITDKNEYGVDMVILAVGFRPNTALGAGKIELFRNGAFLV
                     NKHQETSIPGIYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTALEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKCLGFDAAVTEYTDNQKPEFIEHGNFQVTIKIVYD
                     KESRRILGAQMASHEDISMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAE"
     gene            complement(9879..10481)
                     /locus_tag="TV193_001093"
     CDS             complement(9879..10481)
                     /locus_tag="TV193_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEL1513295.1"
                     /translation="MFRVLKRILGLAVLIFCLYEAVTIHKNVHRVLQYKPTVERILAE
                     NGNKADVDLVLAMIYTETKGGEADVMQSSESSSGIRDSITDSQSSIEYGVRLLSHNLA
                     LAEKAGVDPWTAVQAYNFGTAYIDYVAKNGGQHTIELATNYSRTVVAPSLGNTTGKTY
                     FYYHPLALLSGGKLYCNGGNIYYAQEVHVNLYLIELMSLF"
     gene            complement(10482..11459)
                     /locus_tag="TV193_001094"
     CDS             complement(10482..11459)
                     /locus_tag="TV193_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEL1513296.1"
                     /translation="MLDIYIKGIVIHQFTPNDTELILSDALVAITPRIDEYFRKKLAK
                     VFSDDAKRGQLEADHAFFTTIGTELLETSVTIAKLWKEEFVASEHQKTNDLVFIQFDK
                     EGVPYLAFLRIALKEHFAHLSDDHENPITITQNNLPSPTQAPDEALVINRQTGYYYLI
                     EKRMKHNGSFAHYFSEKLLKVTPEQSVKKSIQMLEQTAQKVAENFNQDDFAFQSKMKV
                     ALAKNLEEETALSPEKLADQLFDQNLTARLTFVDQVKEMIPEPIQVSDIDHSRQLKKL
                     ETQKLSLSNGIELLVPNAVYQDAESVEFILNDNGTYSILIKNIEDIKNN"
     gene            complement(11462..12721)
                     /locus_tag="TV193_001095"
     CDS             complement(11462..12721)
                     /locus_tag="TV193_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEL1513297.1"
                     /translation="MMFNNENYKDYDQELWEAIQAEEDRQEHNIELIASENMVSKAVM
                     QAQGSVLTNKYAEGYPSKRYYGGTEYVDIVESLAIERAKKLFGAAYANVQPHSGSQAN
                     AAAYMALINAGDTVLGMDLAAGGHLTHGSPVNFSGKTYQFVGYTVDKETEKLDYAAIL
                     KQAKAVQPKLIVAGASAYSRQIDFEQFRFIADQVGSYLMVDMAHIAGLVAAGLHQNPV
                     PYAHIVTSTTHKTLRGPRGGLLLTNDEAISRKMNAAIFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFTDYARAVIANTAAMAEVFAKDDRFRLISGGTDNHLFLVDVTKVIENGKLAQ
                     ALLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVDESRTIAHLIIKALVN
                     HQQPEILEEVRYEVRRLTDAFPLYKKN"
     gene            complement(12733..13164)
                     /locus_tag="TV193_001096"
     CDS             complement(12733..13164)
                     /locus_tag="TV193_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1513298.1"
                     /translation="MLRPLDQTDCQAICDINDQSLGYKVSLELTKSQLEKLRSDKHHY
                     LLGYADTKTNLLLGYLHAECYESLYSEKGFNILALAVRLDHQGRGIGRRLLAALEEKA
                     KQEKVSFIRLNSASHRTEAHAFYRKLSYVDDKTQLRFMKLL"
     gene            complement(13178..13771)
                     /locus_tag="TV193_001097"
     CDS             complement(13178..13771)
                     /locus_tag="TV193_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEL1513299.1"
                     /translation="MITHLIETIKAGGALILPTETVYGLFAQALNEEAVNAVYRLKKR
                     PRDKAMNLNVADFESILAFSKQQPAYLNKLYEAFLPGPLTIILKANAQTPYWINSGLK
                     TVGFRLPSHPLTAKIIRATGPLIGPSANLSGSKSGKCFNDIVKAFDGKVDGYADDAYL
                     TGKDSTILDLSSPKVSILRQGAITKEQLLAKVPELPF"
     gene            complement(13743..14591)
                     /gene="prmC"
                     /locus_tag="TV193_001098"
     CDS             complement(13743..14591)
                     /gene="prmC"
                     /locus_tag="TV193_001098"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEL1513300.1"
                     /translation="MNYAKQLRAYEDRLENIGEDRENLAYVFKELKQWTSLDFLLHQN
                     QEVTSEDQALLERIFLALSQHVSPQYITGRAYFRDLVLAVDSRVLIPRPETEELVELI
                     LKENDATRKSVLDIGTGSGAIAIALKKARPNWQVTASDISADALSLAYSNALDHHVEI
                     AFEQSDLFSKLSGQFDIIVSNPPYIAYEDKDEVGLNVYQSEPHLALFAAENGFSIYRR
                     IIEQASAYLTTSGKLYFEIGYKQGEGLKRLLSKRFPQKRIRVLKDMLGKERMVVVDDN
                     TFDRDN"
     gene            complement(14588..15670)
                     /gene="prfA"
                     /locus_tag="TV193_001099"
     CDS             complement(14588..15670)
                     /gene="prfA"
                     /locus_tag="TV193_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEL1513301.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTR
                     ETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEDKLKLLL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEIVDALVLYDQTQKLESLNNQ"
     gene            complement(15712..16281)
                     /locus_tag="TV193_001100"
     CDS             complement(15712..16281)
                     /locus_tag="TV193_001100"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEL1513302.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAVPISNDMDIFAFIAELQEKPYCVLIDECQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNELFEGSKYLLLLADKIDEIKTICQYCSKKATMVLRTEHGK
                     PVYEGAQIQIGGNETYIPVCRKHYFHPPI"
     gene            16468..16653
                     /locus_tag="TV193_001101"
     CDS             16468..16653
                     /locus_tag="TV193_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEL1513303.1"
                     /translation="MPFVTIDLFEGRSQEQKIALAREVTEVVSRIAQAPKEAIHVVIN
                     DMPEGTYFPHGEMKTKA"
     gene            16708..>17082
                     /locus_tag="TV193_001102"
     CDS             16708..>17082
                     /locus_tag="TV193_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1513304.1"
                     /translation="MIATDQIKMMGTIIDICIDSSKAKQQAATIRELLTLYNHRFSAS
                     DDSSELMAINHMAGIQPVRVHSDLFDLISIGKEHSLAYPSNLNITLGPLVQSWRIGFS
                     DAKLPDEATIDRRLRLTNPNHII"
BASE COUNT         4803 a         3754 c         3260 g         5265 t
ORIGIN      
        1 cctactactt ttatctattt atcagttacc cattaggctg tcaatcaatc ctctaaagaa
       61 atcaataatt tgctgaagga ttccctgtcc agtctttaag gcttcagtag catcaaagtt
      121 cacgttgata tttttaaagg tagatccggc cttttcaaca atactatcct ttaaagcatt
      181 cagcgttttg gtgaagtttt cattggaaat cacgccacta tttgagaggt taagcgcgaa
      241 attgataata aggttaatct gatcaggtgt tactgccttg gttaacccat aatgatctaa
      301 ggtttctgtt acaatttggc gcaccttttc ctcattaacc ccttctccag cctttgcgac
      361 agcagcttta atatcagtaa gcgcaacatt tagcttatct gcatcatagc ctgttttacc
      421 tgcattttcg gtattgatat tagatagggt tgatagctcc tcttgtgcca gcttcttgtt
      481 ttcctctggg actttggcac catttttttc gagtgaataa taaataccgg ctaaagctga
      541 ttctccagta actgggattg gtgcagctac agtaatattg gcatgctcaa tgcccaaggt
      601 cacagcggcg ttacgataca tatcttgcgt caccttagtg atattttcag gtgttacaat
      661 agttacctta agcgtttctt tagctcccag cttttgaatc ctaactgagg aataaagctg
      721 taggctcgga tcatctgcta cattcatgat actagcatag gcagttgtat ttagggtgct
      781 taatttgtta tcagaagcac tattgtagtg aagcaaggcc aaggtttgct ctctttgctc
      841 agcagacagt gaatagccta aaacgtaatc aggctgaaca taggtttcat caattacctg
      901 ttgaacatta ttagctgcag cgtgtactgt ttgaagcata aataccgaag ccaaagccat
      961 actggctgct attaatttct tttgataagt catttttcta cctcttttgt gttataaatt
     1021 ttcctttacg agaatcctcc agaaaagacg attaaagcca aagtatctag gtgcctagta
     1081 agaccgtttt acttagctct gcaaagggca atattcctag tctttttcaa aatctaacgc
     1141 ctctattgta gcatttttac ctcaataaga cgattaaaaa gctgaaacaa agcatagcta
     1201 gaatggccaa gcactatttt tacaacaaaa aaactagtgc ataatggcag cttagatgta
     1261 gctactatca ctagtccaat gattatctta tgcagcaacc agtctttatg atctgaggtt
     1321 ttcttgatgg ttattgtcct ttaaatagaa ataataatga tcatcagttt tgatgacata
     1381 gccattttta acctcattaa tcacgtcctt ttgatcaaac tggtagtcct taggcggtaa
     1441 taactctgag gaaaaaaggc tatcataagg cacctcacca ttgtaaaaat ggtaatggtc
     1501 accatgagag gtaacaaaac catcatccga gatagacaca ataatttgct ctgctgctat
     1561 cccctcttcc ttgctaactt cattaggact tttgtcagtc tctttcttta aggctttgca
     1621 ccttttttcc aattgatgag atgattttag cttcttgcct gtgctatctt gggctttaaa
     1681 gtcacaagcg gacaaaggaa ataatagtaa gatagtgaat aacgataaat aagctttttt
     1741 ggtcatgttt cactctccaa tacacgatat agtgtttcta aattcatttt taaatgctct
     1801 agataagttt tttgatcagc tggaaccacc tcaagcgggc ttaggatatc aattgctaca
     1861 ccgttacttt gagccaaggt tttggctagc ttatctgaag cattttcttc gacgaaaatc
     1921 gtcttcacat catatttttt gataaagcgg tcaatttgag ctaattggcg aggactaggc
     1981 tcttgctcag gagatatccc tgcaattccc aattgcttta gatcaaatct cttagctagg
     2041 taggaaaagg ctgtatgctg tgtcacaaag gttttcctac ctagagattc aaacttttcc
     2101 ttataggtct tcactaattt ttgagcctta gccttaaaac gcttagcatt ttgcaaataa
     2161 actgccttgt gagcaggatc tttttgactc aataaagctg caatctgctc tgcctcttga
     2221 ctagctaaga taggatcagt ccaagtgtga ggatcataca aggcatcggt attcattcct
     2281 ttttttatgg tgaagtgctc caagccttga accttgtcta atgttagatg tgatgtcccc
     2341 tccatgactg ctaatccctt tttttccagc tgtggtgcca aatccgcagc ccaagcttct
     2401 aatatcttgg aatggtaaat aaagacatct ccatcgtaaa ccttagcaac aactgtcgga
     2461 cttggctcat acgagtgtat gctagtgttt tgggcaatga cctgaacatc atttaaatcc
     2521 ccgcaaatct cctttgtcat agcataaata ggataaaagc ttgtttttat gaccaaaccg
     2581 gccttcctac tgctagagct ctgatgacag gctgatagac ccaaaagtac tgctaatagt
     2641 cctactgcga caattgtttt cttgaatcct ctaatcatat ctactctctt aactagttaa
     2701 tgacctaaaa aggataccat gatttaactg aaatgtcaat attttatcat tttagcgcac
     2761 gacgtacacg catgaagaaa atgcatgtaa gcctttttta gccccatgca ttttttaatc
     2821 tatttctagc gttttgacat tgcaatatca tcagtttgtc aatttcaatg tgatgacttc
     2881 atcacatttt gctaaaaagg ccatagtgat gataaaaaac cgctaccaga aagcgtaaat
     2941 gtcttcttgc ttttgtcgtg attttagtga accgcctacc aactgaactg atgctggctt
     3001 aaccatttcc tggccaccat caaaagcctg cctctcaatt aacaagctta ctcaaggaag
     3061 aggtgactga gccatgcatc cgtcttagtt atgactaaca gcttatcttg gcatttcatt
     3121 catgtaattc cagtggcagg ccatcaggat caaaaaagaa ggtcatcttc ttaccagtat
     3181 aatcatcata cctaagaggc tcgacagcaa tgcccttagc cattaattgt tcaatataag
     3241 cttcaatagg cttaacatga aaagctaaat gacgaagccc acaggcctct ttgtcatatt
     3301 cgggcctacc gatacgctta ggcggtgcct gataagctgg atcagtcttt ttattgccaa
     3361 aaatctctaa ttcaatggct ccacatttta aatccaattt gtaatcatgt ctatcaggcc
     3421 ggtgattttc acgaataatc tcaaagccaa gcttattgac ataaaaatcc ttagagacct
     3481 cataatccga aacaatgata gcaatatgat gaatagcctt aagctccata tgatttagtt
     3541 cctttattaa ataaaaaaag tgaaacaaag caatgccaag attactttgt ttcacccctc
     3601 gtagcgaccc ctcgcctaga ttaggcttag gttgacatct gattgtaaga gtgattaaag
     3661 gccttcaaaa catcgtcagg tgctttgtta aactcatact cgtttttgat tgctcctttg
     3721 acaatgattc gctctgttgc ctcataatcc gtacaggtga ccaaggttac ctcctttagc
     3781 cctggtgtgt cattgataac atctattctc tcaggtgtga ccgtaaagac ggcattgatc
     3841 tcgtactcgt aaatacgctc cttatctgta aggtaaatag acatcccttc ttttgctctt
     3901 tcaagcggtg agaataacat ttcagaagag cctgttagtc caaaaatatg atgactggct
     3961 aaggagtaat tgttttctcc tcccataacc tggtcctctt tcatggtacc agcaccgtat
     4021 ataagctctg tgttgccaag ccctttaaag attggtaggt taataccaag ctctggtatg
     4081 gcaatacctc ctattactgg aagctgctgg gcgtccattt gagcctgtaa gacactttcg
     4141 gtgctaactg gctgaactgc ttgaaaatca aagcttgact ttgcttcctt attcttttta
     4201 atcgtctttt ttgaaacctt tgtaacttga tatttattag aattccaagc aatcagggtg
     4261 tttctaatgg gcttgttaaa taacaaggct aagcctatga ttaacaataa gacgactaga
     4321 atacctctag caaaggacat ctttcttcgt ttttgtcttc tcctgtgggt tctttttgcc
     4381 attcatttac tccttgctag aatttattgg tgcttctgtt aaagctgtat cagtctgagc
     4441 gattgctgtt ggatcgttgt cttcagcctg taccaaggta aaggtaacaa tcttagaatc
     4501 tgtatctagc ctcataacct taacaccaag tgttgaacgg ccagtctgag aaatacttga
     4561 aacattggta cgaataatca cacccttcgt tgtgatcacc ataatatcct cactgccatc
     4621 aacagtcatc aggccagcca actggccatt ttttgcggtg atattagctg ttttgattcc
     4681 ttttccacct cgacccttag ttgggtattc ggctgcactg gtacgcttac catagccatt
     4741 ttcggtgatg actaagacct cttgcttgtc attgatacga gaagctccga caacccaatc
     4801 ttcctcacga agcttgacac cacgaacacc cgtagcgcta cgccccatgc ctcgaatggt
     4861 agcttcatta aagcgaacag aataacctga tcttgttcca atgataatat cttcctgacc
     4921 atttgtcaag agaacattaa tcagctcatc tccttccttg agattaaggg ctcgtagacc
     4981 attctgacga atattgctaa actctgatac ctcagttcgt ttgacaatcc cttgctttgt
     5041 tgtaaagaag aaatatttat caagaatgtc ttctttttta gcattgataa ttgtttgaat
     5101 ggtttcacca tcatctagct ttagtagatt gataacagga agtccttttg cagcacgtcc
     5161 atattctgga atctcatagg cctttaagcg atagacgcgc ccaaaattgg taaagaaaag
     5221 caatgtgtca tgtgtacttg ttgagacaag ctcacgaaca aagtcatcgt cattgacacc
     5281 tgttccctgt acaccacgac caccacgctt ttgagatcga aactcgtctt gagcaaggcg
     5341 cttaatgtag ccattgtttg atagggtgat caaaacatct tcttcctcga tcaaatcctc
     5401 atcttctaat gacaatacct caccaatcat caattctgtg cggcgaggat tagcgtactt
     5461 gcgcttgatc tcctccattt cttccttgat gatggcttcg atacgctctg gccttgccaa
     5521 aatatctgcc aaatctgcaa tcaaagccag taggtcatcg tattctgatt gaattttatc
     5581 acgttccaag ccggtcaaac ggcgaagacg catgtctaaa atagcctgac tttggcgttc
     5641 agacaagtca aaacgagaca tcaattctgc ttgtgcgata atatctgtct cgctattgcg
     5701 gataatggca ataacctcat ctagatggtc aagagcgata agtaagccct ctaaaatgtg
     5761 tgccctagct tctgccttgt ccttgtcaaa ttgagtcctg cgtgtaatga cgtccttttg
     5821 atgtagaata taattatcaa taatctgtct cagtgacaag attttaggaa tcccgccttc
     5881 aatggctagc atattgaagc taaagtttgt ctggagactt gtcaatttga ataggttatt
     5941 taaaatcaca ttagcagatg catcgcgacg gacttcaatg acaaatcgta ccccttgtcg
     6001 gcttgattcg tcacgaacag ctgtaatgcc ctcaatacgc ttttcttggg ctaagcgaac
     6061 aatatgctca tggacctttg ttttattaat gccataaggg aattctgtga cgacaatccg
     6121 ctcccgtcct gtactagtgg tttcaatctc ggtgcgtgaa cgcaaaacga ttgatccctt
     6181 accagtctca taagccttat gaattcctga acgtcccatc accaaggcac ctgtaggaaa
     6241 atccggccct ggaagaacct ccattaaatc tctggtagtg cagtcaggat tttccatgac
     6301 catcttaaca gcgtctatgg cctcagctaa attatgaggt ggaatattgg tagccatacc
     6361 aactgcgatt ccggtggcac cattgaccaa taaattgggg aagcgagccg gtaagactaa
     6421 gggttctctt tcattaccat cgtagttatc ctgaaagtca acagtatttt tattaatatc
     6481 ctttaagagc tctagcgcga ttttgctcat acgagcctca gtataacgct gagccgcagc
     6541 accgtcaccg tccatagaac caaagtttcc atgaccatcg acaagcatgt gacgatagct
     6601 ccaccactgg gccatacgga ccatcgcttc atagatggac gaatccccat gtgggtggta
     6661 cttacccatg acatcaccgg taatacgagc agatttttta tgtggcttat caggtgtgac
     6721 gcctagctca ttcatgccat aaaggatacg acgatgaaca ggctttaagc catctcgtac
     6781 atctggaagt gctcttgcta caataacgct catagcataa tcaatgaaac tcgttttcat
     6841 ctcacttgtc agattgacgt caactaaatg tttatcttgc atttaaggaa tgctcctttt
     6901 ctagtcaata ctcttttaat tataccataa aatccttatt ttttctgatt ggaaacgctg
     6961 tccgaaaaca attttcataa tttggtcgaa tatcatgaca aagacattaa aatgtgttaa
     7021 aataagatcg tatgagcaat ttgctctaac taaaatgaag gagatgttta gaaatgactg
     7081 caactaaaca acataaaaaa gtcatcttgg ttggcgatgg tgctgtaggc tcttcttatg
     7141 cctttgcact agtaacccaa aatattgccc aagagcttgg tattattgat atttttaaag
     7201 aaaaaactca aggagatgct gaggatttaa gccatgcgct tgcctttacc tcccctaaaa
     7261 agatctatgc tgctgattat gctgactgtc acgatgctga cctagttgtt ttaacagctg
     7321 gcgctcctca aaagccaggt gagactcgtc ttgaccttgt tgagaaaaat ctacgtatta
     7381 ataaagaagt ggttactcaa attgtggcct caggctttaa gggaattttc cttgttgctg
     7441 ctaatccggt ggatattttg acctattcaa cctggaaatt ctcaggtttc cctaaggaac
     7501 gcgttatcgg ttctggaaca tcacttgact cagcacgctt ccgtcaggca cttgctgcca
     7561 aaattggtgt agacgcacgt tctgttcatg cctacatcat gggtgagcat ggagattcag
     7621 aatttgctgt ttggtcacat gctaatgttg caggggttgg attgtacgac tggcttcaag
     7681 ctaatcgtga cgttgatgaa caaggcttgg tagacctctt tatctctgta cgtgacgcag
     7741 cttactctat catcaataaa aagggtgcta ccttctatgg tattgcagtc gccctagcac
     7801 gtattacaaa agctatcctt gatgatgaaa atgcagttct tccactttct gttttccaag
     7861 aaggccaata cgaaggcgtt gaggattgct atatcggtca gcctgctatt gttggtgcct
     7921 atggtattgt tcgtccagtc aatatcccat tgaatgacgc tgagcttcaa aaaatgcaag
     7981 cttcagcaaa ccaattgaag actattatcg acgaagcctt ctctaaagaa gagtttgcgt
     8041 ctgctgctaa aaactaatta aaaaatgaat gtgttagatc ttgctctaac gttttggaat
     8101 cactacaaaa agcctaatcc aatcggatag gcttttttca tgcgtctaac agcgaggtgc
     8161 aagacaaagc acgctttcat taagcatcgt gtgtgctatg cttatagtct taagtcacaa
     8221 aaaagacaac cagctttatg agctggctgc ttattagctt gttattcagc accaagtgct
     8281 gccattgtaa tgtagttata tggcttgtta aagtgcggta agaagaaaat atcagtcaaa
     8341 gctaatttct caatggtcac tccttcttgg atagcaagtg agaacatatg aattcccatt
     8401 gaaatatctt catgtgaggc catttgagca cctagaatac gacgtgattc tttatcgtag
     8461 acaatcttaa tggttacttg gaagttacca tgctcgataa attctggttt ttgattgtca
     8521 gtgtattctg ttactgctgc atcaaagcca aggcattttg ctttctcaag agttaagcca
     8581 gttgatacca tgtgcaagcc gtagatagag ataccatttg atccctgcac accaataccc
     8641 tcaagagctg tgccacaagc gttatgagct gcgacaatcc ctgtacgaac agcatttgaa
     8701 gcaagggcaa tataattggt atcgcgagtt gcgttgtcat agatggttgc acaatcaccg
     8761 attgcataaa tccctggaat agatgtttct tggtgtttgt taacaaggaa ggcaccatta
     8821 cggaaaagct caatcttgcc agcaccaaga gctgtatttg gacggaagcc aactgcaagg
     8881 ataaccatat caacaccata ttcattctta tcagtgatta gcttttcaac cttgccatca
     8941 ccagcaacct ctttgacagt ttccccaaag gccaactgaa taccatgctc ttctaggttt
     9001 ttagacatga catctgtcaa atcacgatca tagtagcctg ctagacaagt atccgcaaca
     9061 tcaatcagaa taacctcttt gcccttacgt tggaaggctt ctgcaagctc tacaccaatg
     9121 tagcctgcac caacgactgc aacgcgctta atgtctttgt tttctaattt cgaaatgaca
     9181 tctgctgaat tttggtacaa tttaacgaat tgaagatttt caagtgttgc ttcaaactct
     9241 aatgagccct ctttgatttc tgcaccttta attggtggca agataggctg tgaaccagtt
     9301 gcaaaaatta atttgtcata tgactcaaca tgctctttgc catcaacaag ggctgtcact
     9361 gttttagcat cgtagtcaat agattgaact ggtgattcca tgtaaacctt agcaccaagg
     9421 gactctagct cttccttatt tgagtagaat aagccctctg ggccagaaat ttgttcgcca
     9481 atccaaagtg ccataccaca gcctaagaat gaaatatttg agttttggtc aaatacaaca
     9541 atctcattag catcaccata gtttgttaac atagtcttga tacatgccgt acctgcgtgg
     9601 tttgcaccga taacaacgat tttactcata tgattatgtt cctcatttca caatttatat
     9661 taggtctcta ttataacaca gggaaaaagc gcttccaact aaaatgctca tttttcttgc
     9721 ttttttatac cgttttttag tcaataaata agacagccta tcatttgttg aagggtcgta
     9781 caaagaccgg tttgcttcag ttaagtcaag acgacattct tattcaacta ttttcccaaa
     9841 ttcattacat gattaagacc attttttgtc gttaacttct aaaaaagact cataagctca
     9901 atcaggtaaa gattgacatg tacctcttga gcataataaa tattgccgcc gttgcaataa
     9961 agctttccac cagagaggag ggctaagggg tggtaataaa aataggtttt tccagtagta
    10021 tttcctaggc tgggtgcaac gacagttcta gaatagttag tggctagttc aattgtatgc
    10081 tgaccgccat ttttagcaac gtaatcaata taggcggttc caaaattgta agcttgaaca
    10141 gctgtccaag ggtctacgcc ggctttttct gctaaagcta aattgtgaga tagcaatctg
    10201 acaccatact caatgctaga ttgactatcg gtgatcgaat cccttatgcc agagctgctt
    10261 tcgcttgact gcataacgtc agcttctcct cccttagttt ccgtgtatat catggctagt
    10321 accagatcga cgtctgcttt gttaccgttt tctgctaaaa tacgctctac tgttggcttg
    10381 tattgtagga ctctgtgcac attcttatga atggtaactg cttcgtacag gcaaaaaatg
    10441 aggacggcta atcctaagat acgctttaac actctaaaca tttagttatt tttgatatcc
    10501 tctatatttt ttatcaatat ggaataggtt ccgttgtcat tcaagataaa ctctactgac
    10561 tcagcatctt gataaactgc attagggaca agaagctcaa ttccatttga cagcgacagc
    10621 ttttgcgtct ctagcttttt tagctgtcta gaatgatcaa tatcactgac ctgaattggt
    10681 tcgggaatca tttccttgac ctgatccaca aaggttaacc ttgcagtcag gttctggtca
    10741 aataattgat ctgctagctt ttctggagat agagctgttt cttcttctag atttttagcc
    10801 agtgctactt tcatctttga ttgaaaagca aagtcatctt ggttaaaatt ctcggcaacc
    10861 ttttgagcgg tctgctcaag catttgaata gattttttga cagattgctc aggtgttacc
    10921 tttagcagct tctcagaaaa gtaatgagca aagcttccat tgtgcttcat gcgtttttcg
    10981 attaagtagt aatagcctgt ttgacggtta atgaccaagg cttcatcagg tgcctgagta
    11041 gggcttggca aattattttg cgtgatcgta ataggatttt catgatcgtc tgatagatgg
    11101 gcaaaatgct cttttagggc aatgcgtaaa aaggccagat aaggcactcc ttccttatca
    11161 aactgaataa aaaccaaatc gtttgtcttt tgatgttcag aagcgacaaa ttcttccttc
    11221 caaagcttgg caattgttac tgatgtttcc aaaagctctg taccgattgt ggtaaaaaaa
    11281 gcatgatcag cttctaattg cccacgttta gcgtcgtcag aaaaaacctt ggctaatttt
    11341 ttgcgaaaat actcatcaat tcttggtgtt atagctacta aagcatctga taagatcagc
    11401 tcggtatcgt ttggtgtgaa ttggtggatc acaattcctt ttatataaat atctagcatt
    11461 gttagttctt cttgtataat gggaaggcgt cagtcaatcg gcgaacctca taacggacct
    11521 cttcaaggat ttcaggctgc tggtggttaa ccaaggcctt gataattaaa tgagcaatag
    11581 tcctactttc gtctactccc attccacgac tggtaatggc agcgcagcct atgcgaatgc
    11641 ctgatgtttt aaagggagat agggtctcaa aaggaatagc atttttgtta agggtaatat
    11701 taacctcatc aagcaaggct tgagcaagct tgccattttc aatcacctta gtcacatcaa
    11761 caaggaaaag atggttatct gtaccgcctg agatcagacg aaaacgatca tccttggcaa
    11821 aaacctctgc cattgctgct gtatttgcta taacagccct tgcatagtct gtaaaggcag
    11881 gatcaagcgc ctccttaaac gcaacagcct tcgctgctat gacatgctcc aaaggcccac
    11941 cctgtagacc agggaaaata gctgcattca ttttccttga aattgcttca tcatttgtca
    12001 aaagcaggcc accacgagga ccacgaaggg ttttatgagt ggttgaggtc acaatatgag
    12061 cataaggtac tggattttga tgcagacctg ctgcaaccaa gcctgcaatg tgtgccatat
    12121 ccaccatcaa ataggatccc acctggtctg caataaaacg aaattgctca aaatcaatct
    12181 gccgagaata ggctgaggca cctgcaacaa tcaacttagg ctgaacagcc ttagcttgct
    12241 ttaggatagc tgcgtagtcc agcttttcag tttccttatc gacagtgtag ccgacaaatt
    12301 gataggtttt tccagaaaaa ttgacaggtg agccatgtgt caagtgacct ccagctgcca
    12361 aatccatacc aagcacagtg tcaccagcat taatcagtgc catataagca gcagcattgg
    12421 cctgactacc agaatgaggc tgaacgttgg cataggctgc accaaagagc tttttggcac
    12481 gctcaatagc aaggctttca acaatatcaa catactctgt gccgccataa taacgcttgc
    12541 ttggatagcc ctcagcgtat ttgttggtca agacagagcc ttgtgcttgc ataacagcct
    12601 ttgagaccat attttcagaa gcaattagct caatattatg ctcttgcctg tcctcctcgg
    12661 cctgaatagc ctcccaaagc tcctgatcat agtctttgta gttctcgttg ttaaacatca
    12721 ttattgtctc ctctataata gcttcataaa tcgtaattgt gtcttatcat ctacatagct
    12781 cagcttacgg taaaaggcat gtgcctcggt cctgtgacta gcagaattaa gccgaataaa
    12841 gcttactttc tcctgcttag ccttctcctc taaagcagct agtaagcgac gaccgatacc
    12901 tctaccttga tggtccagcc tcactgctaa ggccaaaata ttaaagcctt tttccgagta
    12961 aagcgactcg tagcattcag catgcagata gcctaagagc agattggtct tagtatcagc
    13021 atagcccagc aaataatgat gcttatcgga tcttagtttt tccaattggc tttttgtcaa
    13081 ttcaagagaa accttgtacc ccaaggattg atcattaatg tcacaaatag cttgacaatc
    13141 tgtttgatct agtggtctta gcatagcctt acctcctcta aaatggcagc tctggaacct
    13201 tagctaataa ttgctcctta gtaatagcac cttgtcgtaa aatactgacc ttaggtgacg
    13261 ataaatccaa aatagtagaa tccttccctg tcaaataggc atcatcagca taaccatcaa
    13321 cctttccatc aaatgccttg acaatgtcat taaagcattt tccactcttt gagcctgaca
    13381 ggttagcaga tggcccaatc aagggacccg ttgctctgat aattttagct gtgagagggt
    13441 gactgggtag tcgaaagcca actgttttta gcccagaatt aatccaatag ggtgtctggg
    13501 cattggcttt taggataatc gtaagtggac caggtaaaaa agcctcgtac agcttgttaa
    13561 gataggcagg ctgctgctta gaaaaagcca aaatactctc aaaatcagcc acattaaggt
    13621 tcatagcctt gtcgcgaggc ctttttttga gacgataaac agcattaaca gcctcttcat
    13681 ttaaggcctg agcaaaaaga ccataaactg tctcagttgg taaaataaga gctccaccag
    13741 ccttaattgt ctctatcaaa tgtgttatca tcaacaacca ccattctttc tttacccagc
    13801 atatccttaa gcactctgat acgcttttga gggaaacgct tggataagag cctttttaag
    13861 ccttctccct gcttgtagcc tatttcaaaa tagagcttac cacttgtcgt cagataagca
    13921 ctagcttgtt cgataatgcg tcggtaaata gaaaagccat tttctgcagc aaataaggcc
    13981 aaatgcggct cagattgata aacattcaag ccaacctcgt ccttatcctc ataggcaata
    14041 tagggagggt tagaaacaat gatgtcaaac tgccctgata gcttgctaaa aaggtctgac
    14101 tgctcaaagg ctatctctac atgatgatct aaagcgtttg agtaagcaag gctcaaggca
    14161 tcagctgaaa tatcagaggc tgtgacctgc cagttaggtc ttgctttttt taaagcaatt
    14221 gcaatagcac cactgcctgt tccaatgtct aaaacggatt tgcgagtagc gtcattttcc
    14281 ttcaagataa gctcaactaa ttcttccgtc tctggtcttg ggattagcac gcgcgaatcc
    14341 actgcaagca ccagatctct aaaataagcc ctgcctgtga tatattgtgg cgatacatgc
    14401 tggctaagcg ctaaaaaaat ccgctctaat aaggcttgat cctctgaagt gacctcttga
    14461 ttttgatgaa gcaaaaagtc aaggcttgtc cactgcttta attctttaaa aacataggcg
    14521 aggttttcac gatcctcacc tatgttttct agcctgtctt cgtaggctct tagttgctta
    14581 gcatagttca ttggttattt agcgattcta atttctgagt ttgatcatat agcactaaag
    14641 cgtcaacaat ctcgtctaac tttccagaca aaatggtgtc taatttttgc agggttagac
    14701 cgatacggtg atctgtcaca cgattttgtg ggaaattata ggtccgaatc cgttcagaac
    14761 gatcacccgt accgatagtt gatttacgct ctgcgtcctg ctcgtcctgt gcgatctgtg
    14821 caaaatgatc tgctacacgt gcccgaataa tcttcatagc cttgtcacga ttcttttgct
    14881 gcgttctttc ctcttgcatc tcaaccttga tgtttgttgg gagatggacg atacgaacag
    14941 cggttgccac cttgttgaca ttttgtccgc cagcaccaga agcatggtaa atatcaatac
    15001 gaaggtcctt tggatcaatg tcgtactcaa cttcttctac ctctggcatg actaagacag
    15061 tcgcagttga agtatgcacg cgcccttggc tttctgttac aggaacacgc tgtacgcgat
    15121 gagcacctga ttcgtatttt agcttggaat aaacagattg tcctgaaacc atagcaacaa
    15181 cctctttaat ccctccaaca ccattatagg aagcctccat tacctcaaag cgccagcctt
    15241 ggctttcggc aaatttttgg tacatggcta agagatcacc ggcaaataga gcagcctcat
    15301 caccacctgc ggcaccacga atttccaaga taatattttt atcatcattt ggatctttgg
    15361 gaagcagcaa aagctttaac ttgtcctcat aggcttcctt ggcagacttg gcctctttta
    15421 gctcctcctt ggccatctct tcaatgtcag gatcgccgcc ggcttcctta atcatctcct
    15481 cagcgtcatc aatggattgg ataatagcct tatactgacg ataagctgct actgtttctc
    15541 gtgtgctagc ctcttccttt gacagagcca taaaacgttt ggtgtcagaa acaacctccg
    15601 gatcacttaa taattcgcct aattcttcat aacggtcctc aacagcctgt aattgatcat
    15661 aaatattcat tagggggtat tctctcctct ttttacttgt tttagttgtt attagattgg
    15721 tgggtgaaaa taatgcttgc gacaaactgg aatataggtc tcattgccac caatttgaat
    15781 ctgtgctccc tcataaacgg gcttaccatg ttctgttcgc aataccatag ttgctttttt
    15841 gctgcaatat tgacagatgg tttttatctc atcaatctta tcagctaaca gtaacaggta
    15901 tttggagcct tcaaacaatt cattttgaaa atcatttttt aagccaaagg ccatcactgg
    15961 aacatttagc tcatcaacca cacgtgctaa atcatagaca ttttgcttgc ttaaaaattg
    16021 acattcgtca atcaagacgc aatagggctt ctcctgcaat tcagcaataa atgcaaaaat
    16081 atccatatca ttcgaaattg gtacagcctc acgacgcatg ccaatccgac tagaaacaat
    16141 gccaaagcca tcacgtgtgt ctagcgcact tgtcataatc acaacaggct tcccctgttc
    16201 ttcataattg tgtgctacct tcaagatttc aatggtcttt cctgaattca ttgttccata
    16261 tttgtaatat aattgagcca aaatggagat tcctaccttc ttcttttgtc ctacttattc
    16321 tatcatattt gtccctattt ggcgattgcc ttatctgaaa atcttatttt cacaacagct
    16381 aaatcctgtg ctgttgagct aaggttaggc tttttgaagc tgacatgcta caatagaggt
    16441 atcattaaaa aaaggagatt gactattatg ccatttgtaa cgattgacct gtttgagggg
    16501 cgtagccaag aacaaaaaat tgccctagcg cgtgaggtga cagaggttgt ttctcgtatc
    16561 gcacaggctc caaaagaagc gattcatgtt gtaatcaatg acatgcctga ggggacctat
    16621 ttcccgcatg gtgagatgaa aaccaaagcc taatgcctaa gtcccactta tctaggtggg
    16681 cttttcctat ttgaaaagga gggcctgatg atagctactg atcagatcaa gatgatggga
    16741 acaatcattg atatttgcat tgactcatca aaagcaaagc agcaagcagc tactatccga
    16801 gagctactaa ccctttacaa tcaccgtttt tcggccagtg acgacagctc tgaattaatg
    16861 gcaatcaacc atatggcagg tattcagcca gtgcgtgtgc attcagattt gtttgactta
    16921 atctcaatcg gaaaagagca tagcttggct tatccaagca accttaatat cacacttggt
    16981 cctttagtgc aaagctggcg catcggcttt tcagacgcta agcttccaga tgaagcaact
    17041 attgatcgca gactaagact aaccaatcct aatcatatca tc
//
LOCUS       DARYXS010000041        16850 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.042, whole genome shotgun sequence.
ACCESSION   DARYXS010000041 DARYXS010000000
VERSION     DARYXS010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16850
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.042"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(173..925)
                     /gene="pstB"
                     /locus_tag="TV193_001103"
     CDS             complement(173..925)
                     /gene="pstB"
                     /locus_tag="TV193_001103"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1513305.1"
                     /translation="MGAFSTKQLNVFYGAFQALKDISIDIPENQITALIGPSGCGKST
                     FLKTLNRMNDLIPSCRIEGEVLLDNQDIYAKAINLNSLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGLKDKKTLDQLVEQSLRGAAIWDEVKDSLKKSAMSLSGGQQQRLCIARA
                     LAVAPDVLLMDEPTSALDPISTLKIEDLVQQLKQDYTIIIVTHNMQQASRMSDKTAFF
                     LTGDICEFGDTAELFTKPKDKRTEDYISGRFG"
     gene            complement(927..1742)
                     /gene="pstA"
                     /locus_tag="TV193_001104"
     CDS             complement(927..1742)
                     /gene="pstA"
                     /locus_tag="TV193_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1513306.1"
                     /translation="MTNYLLKALVYLLSLLTFGSLFLIIAFMLIKGLPSLSLSLFSWT
                     YTSDNVSLMPSIISTVSLVLGTLVLALPIGVFAGFYLVEYAKQDSLWVRAIRLAADTL
                     SGIPSIVFGLFGMLFFVVFFGLQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDHLRQ
                     ASLGLGAGKLRTIFKIVLPAAMPGILAGVILAIGRVVGETAALMYTLGTSTNTPTSLM
                     SSGRSLALHMYMLSSEGLHVKEAYATGVILLITVLLINALSSLLSRRLVKGVV"
     gene            complement(1735..2598)
                     /gene="pstC"
                     /locus_tag="TV193_001105"
     CDS             complement(1735..2598)
                     /gene="pstC"
                     /locus_tag="TV193_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1513307.1"
                     /translation="MNKQAFKEDFFKVIFFLSAAMAIIAICLICIFIFSNGLPFIAKY
                     GMRAFLLGNDWSPSNQPASYGILPMIAGSFVITLGAMVIGVPTGILTSVFMVYYCPKA
                     CYGFLKSAVNLMAAIPSIVYGFFGLQVLVPWIRSFAGNGMSVLTASLLLGIMILPTLI
                     SLSESAIRAVPKAYYSASLALGASHERSIFRVILPAAKSGLFSALILGFGRAIGETMA
                     VILVAGNQPVLPSGLFEGTRTMTTNIVLEMAYASGQHREALIATSAVLFGFILIINAC
                     FAYVKGKSAHD"
     gene            complement(2668..3540)
                     /locus_tag="TV193_001106"
     CDS             complement(2668..3540)
                     /locus_tag="TV193_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL1513308.1"
                     /translation="MTIKKMLIMAAIGLSGLGLAACGNNSADAGKAADRIDLVSRENG
                     SGTRGAFTEMTGILKKDGDKEIDQTAKTAIIQNSTEGVISSVKGNSRAIGYISLGSLN
                     SDVAALKVNGVKASRETILEGKYPLQRPFNIVWSSDLSGVGKDFITFIDSKQGQEIVR
                     DNRLIEAKTDAPAYSSKGLSGKLSIVGSTSVSPLMEKLAEAYKKENPAISIDITSNGS
                     SAGITAVKEKTADIGMVSRDLTTEESKGLIDDAIALDGIVVIVHKDNKVSNIGIDVLA
                     DVFSGKLTSWDKVK"
     gene            complement(3699..5024)
                     /locus_tag="TV193_001107"
     CDS             complement(3699..5024)
                     /locus_tag="TV193_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEL1513309.1"
                     /translation="MIGHLRRLSMLLGLCLLAALGLIWQGPHQVLTLVVLCTGLVASF
                     YVLSMLFRWEREFRALHHHLLTASDHFLLVGQADLSAYAKQLTELKSDLLQKEARLKA
                     LSKNVEAVTSHLTMGMLLVSNQRELLLTSKSLPAYFPEAKPPFVVLEDLKRMDLIALV
                     NQVFDQKQTLKKELTGLHDGDLILEVTLVPIFNQSHVVKEILVLLYDLTAIRHYERLN
                     LEFIANASHELRTPVTSIKGFAETIKEMPDDETSLKEDFLDIIYNESLRLERIVEHLL
                     TLSKANKTPLDLTEFQLRNFLLYTGQSMRPQLEQKQLELSYALEDSIVVTSDQYLLSQ
                     IMLNLLSNAIQYTDNGGRIQLSSQRVAGGVAITVADTGIGISQIELDRIFERFYRVNK
                     GRSRQSGGTGLGLAIVKELSQLLGGQITVTSQLGEGSQFTLFLPEAINK"
     gene            complement(5008..5730)
                     /locus_tag="TV193_001108"
     CDS             complement(5008..5730)
                     /locus_tag="TV193_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1513310.1"
                     /translation="MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAER
                     EPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMVSAKSDEFDKVLALELGADDYVT
                     KPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
                     TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAP
                     QYIQTIRGYGYKFKELKNDRTS"
     gene            5902..6057
                     /locus_tag="TV193_001109"
     CDS             5902..6057
                     /locus_tag="TV193_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513311.1"
                     /translation="MAITHKKNDQLEKMMAGFASIPDFDKPLELNQDGKLVTEKPKPQ
                     VKTAKQD"
     gene            6098..7000
                     /locus_tag="TV193_001110"
     CDS             6098..7000
                     /locus_tag="TV193_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL1513312.1"
                     /translation="MSLFSNLPPSVLQWFAIFLSIIIEALPFVFLGTILSGCIEVFVT
                     PDLVQRYLPQNKWLRILFGTFIGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLMLRLLGAILVAVSLGIMLAFIVDENILKESTQPVHCH
                     TYSHESLPKRLYLALAHAIDEFFDTGRYLVFGTLIASAMQIYLPTKVLTAIGHSPLTA
                     ILVMMLLAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMLNSFKG
                     AFIVQFISVSAVMITIYCLLVGVL"
     gene            7000..7815
                     /locus_tag="TV193_001111"
     CDS             7000..7815
                     /locus_tag="TV193_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEL1513313.1"
                     /translation="MIRFLILAGYFELTMYLELSGKLNQYINIRYAYLAYISMVLSFI
                     LALVQLYTWTKNIKLHSHLKGKVAQLTSPLILVFPVLVGLLVPTVSLDSTTVAAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMLNELKKYQGKSAITITTDN
                     YMEVMELIYLYPDEFVDRTIQYTGFVYNEPGHDSYQFLFRFGIIHCIADSGVYGLLTT
                     GNQESYANNTWLTVKGQLHMEYDKTLEQQLPVLQIEEAHQAPEPDNPYVYRVF"
     gene            complement(8000..9421)
                     /locus_tag="TV193_001112"
     CDS             complement(8000..9421)
                     /locus_tag="TV193_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1513314.1"
                     /translation="MVCFPKDFLWGGAVAANQVEGAYLTDGKGLSVQDVLPEGGLGDY
                     TAEPTAANLKLEAIDFYHRYKEDVALFAEMGFKVFRTSIAWSRIFPQGDETEPNEAGL
                     QFYDDLFDELIAHGIEPLVTLSHYETPLHLAKVYNGWTDRRMVGFFERFATTVMQRYK
                     NKVKYWLTFNEVNSILHMPFTSGAIMTPKEKLTPQELYQAIHHELVASASVTRLARLI
                     NPAFKIGCMILAMPAYPMTSDPRDILAAKQFEQRNLLFSDIQVRGKYPSYAKSFFKEQ
                     HIDIQFEPGDSELLAQHTVDFLSFSYYMSVTQSHHPDHYQRGEGNILGGLVNPHLPSS
                     EWGWQIDPIGLRITLNDYYDRYQIPLFIVENGLGAKDKLVQTKDGHWTVQDDYRIDYM
                     RQHLLQVAKAIEDGVDIMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRHDDGSGHLTRY
                     KKKSFAWYQRVIETNGRSLSEES"
     gene            complement(9448..11310)
                     /locus_tag="TV193_001113"
     CDS             complement(9448..11310)
                     /locus_tag="TV193_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL1513315.1"
                     /translation="MTYQETAKAIFEAVGGEQNIQEVTHCITRLRLVLKDDKQVVDQK
                     IKLIPNVIGVMRQNGQYQIILGNDVNNYYKAFMTLGQFHETDMSSSAGQKQSMIEGLI
                     ETIASVITPLIPALLGGGMLKVVGILVPMLGLAGTDSQTVAFINFFGDAAYYFMPIMI
                     AYSAAARFKVTPVLAATVAGILLHPAFVTMVATGKPMALFGAPVTPASYGASVIPILI
                     MVYLMQYIEREVNRFVPSVMKSFLQPTLIIFISGFLALVVIGPLGVIIGQGLSNSLLA
                     IYHIAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGS
                     AAVAVACQSKQKQTRQVALAAGLSALLAGITEPALYGITLKFKKPLYAAMISGGLVGA
                     YIGFVNIASYTFVVPSLIGLPQYISPTSSANFTNALIAAGLTIALTFTLTWFFGIDEE
                     VDQEGSADSDSTPVKSGLSAKQSIYAPMVGTVLPLSEVPDETFSSKLLGEGLAILPNE
                     EYVYAPFDGEVITLFPTKHAIALKNAKGVDVLIHVGIDTVELKGQGFEQLVKAGDTVK
                     QGQPLLRIDLELIGSKGYSLVTPFVVTNSSEQLEIIVNDNKEHITQHDVALVIL"
     gene            complement(11315..12154)
                     /locus_tag="TV193_001114"
     CDS             complement(11315..12154)
                     /locus_tag="TV193_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1513316.1"
                     /translation="MIIKRVLNHNAAISTNHQGLDILLMGKGIAFKKRIGDHIDSEAI
                     EASFVLKNSDNMNRFTELFIAVPQEVVACSERLINLGKIKLGKNLDEILYINLTDHIH
                     SAIERHKQGMIISDPLRWEIRRYYPDEYAIGVKALEVIASELGVALAVDEASFIAMHF
                     VNASLDNPFKEPHRMTEIVSYIEQKVKADFKTELDEVSIDYYRFITHVKLFAQRVLSG
                     MAYDDDETDLLLMVKDKYPEEYHCVRQISHHMKKAYHYQLSSSELLYLTVHIKRLVKN
                     VKE"
     gene            complement(12443..13900)
                     /gene="ftsY"
                     /locus_tag="TV193_001115"
     CDS             complement(12443..13900)
                     /gene="ftsY"
                     /locus_tag="TV193_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEL1513317.1"
                     /translation="MGLFERLFGKKDKTKVAEQEAATTEVLSEDITSKDTIESEKEAL
                     SDTNAHAVAADVVSRTDDTSKQAELSDEAASEQAEGLDPAARGAFLLEREPELELAAT
                     DDKTLDQAGESLSQHEAMEEAKHDRAKSEHSNESADASTEDQAETNAEYQVAAQAPAG
                     SADQPAEEGQKQETLSAESDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEDFFEDLE
                     ELLILSDVGVHVATTLTEELRYEAKLENAKKPEALKRLIIDKLVAIYEGDGRYNEAIH
                     YQPGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRR
                     VDVPVITGPEKADPASVVFDGVERAVAERADILLIDTAGRLQNKDNLMAELEKIGRII
                     KRVIPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGIVLAIRQ
                     ELDIPVKLIGFGEAIDDIGEFHSEDFMKGLLEGIL"
     gene            complement(13900..14727)
                     /locus_tag="TV193_001116"
     CDS             complement(13900..14727)
                     /locus_tag="TV193_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1513318.1"
                     /translation="MTRIKLLALDLDGTLYNTEKIVSDENKKALAAAKEKGVKVVITT
                     GRPLKAIGNLLEELDLLGEENYSITFNGGLVQRNTGHILDKSALSLAEVYDIHQQLAA
                     VGLPTDVISDGTVYSLSGNDGRRSQYHLASPLLNFVSLKSFAELPKDITYNKIVTVTD
                     PKVLDQQLARLPKTIFEDFEAFKSRDIIFEIMPKGIHKAFGLDLLCQHLGLEAKHVMA
                     MGDEANDFSMLQWAGLGVAMANAVDQAKEVADAVTTLTNDQSGVAEAIWKYILNEEG"
     gene            complement(14728..15525)
                     /locus_tag="TV193_001117"
     CDS             complement(14728..15525)
                     /locus_tag="TV193_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1513319.1"
                     /translation="MVKLIATDMDGTFLREDGTYDKERLAALLPKLREKGILFTVSSG
                     RSLLAIDHLFEPFLDDIAIIAENGSVVQYKRDILFADVMTKQQCHDIVEKILANPYYN
                     QSGILFSGQKAAYVLKGATEDYIQKMHYYYENVQLIDCLQDIVDDTVFKASTTFTGET
                     VLAGSDWLNQELSYASAVTTGFDSIDIILKEVHKGFGMDQLCQHLGILPEKTIAFGDN
                     LNDYQMLSFAGQAIATENARPEIKAISDQVIGHCNDSAVLTYLEGLV"
     gene            complement(16043..16552)
                     /locus_tag="TV193_001118"
     CDS             complement(16043..16552)
                     /locus_tag="TV193_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513320.1"
                     /translation="MKKKAYMTLILLIGILAIFLVGKQVIKKENPNKPTVDLTVYTIS
                     SSDTQKWNKVRQLETEEAIYLIRVKEAASSEEIFSNIIADGAAMGFGVSEEDVKQFNN
                     HLENTIEDSKNNKLIEMEFFDFSNNNKGFVVANFDYGKKEFNAQKKEKKALYKKLYEA
                     FKEKNHQSR"
     gene            complement(16549..>16850)
                     /locus_tag="TV193_001119"
     CDS             complement(16549..>16850)
                     /locus_tag="TV193_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1513321.1"
                     /translation="ADVLEKVGLSNDYLNQKIYELSGGQVQRVAIARMLMKPRKIILA
                     DEPTGALDSEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDVIIDLKDIGSEI"
BASE COUNT         4836 a         3978 c         3176 g         4860 t
ORIGIN      
        1 gtctgaaaat agctagatcg tgcttatcaa agaaagcaaa aaagcttcac tctacaggaa
       61 gtaagagaga agcttccacg ctaataggat actgatctga catcatcaaa acaccaattg
      121 aggagagatt tagccctcat tccaattgct ctttcatcgc ctagtccttt tcttatccga
      181 agcgtccgga aatataatcc tctgtacgct tgtcctttgg ctttgtaaat agttcagctg
      241 tatcgccaaa ttcacaaata tctcctgtga ggaaaaaggc tgttttatct gacatgcgtg
      301 aagcctgctg catgttgtgg gtaacgatga taatcgtgta atcctgcttt aattgctgaa
      361 ccaagtcctc aatttttaag gtagaaatgg gatcaagagc agaggtaggc tcgtccatga
      421 gcaacacatc aggtgctaca gcaagcgctc ttgcaatgca aagccgctgc tgctgtccac
      481 ctgataggga catggcactc ttttttaagc tgtctttgac ctcgtcccaa atggctgctc
      541 ctctcaagga ctgctctacc agctgatcta gagttttctt gtccttaagg ccatgtgtcc
      601 taggaccata agccacatta tcataaatag acatggcaaa tgggttgggc tgctgaaaga
      661 ccataccaac acgcttacgc agactgttga ggtttattgc tttagcatag atgtcttgat
      721 tgtctaagag aacctctcct tcgatacgac aggaaggaat caagtcattc atgcgattta
      781 gggtttttaa aaaggttgat ttgccacagc cagagggacc tatcagggct gtgatctgat
      841 tttctggtat gtcaatggag atatccttta aggcctgaaa tgctccataa aagacattaa
      901 gctgcttggt tgaaaaagct cccattttag acgactcctt tcactaatcg gcgtgataat
      961 aagcttgata gggcattgat cagcaagaca gttatgagta agataacacc cgttgcataa
     1021 gcttccttga catgtagccc ttcgctagac agcatgtaca tgtgaagagc tagtgagcgt
     1081 cctgatgaca tgaggctggt tggcgtattg gtagaggtgc ctagggtata catcagggct
     1141 gctgtctcac ccacaacacg tccaatcgct aggattaccc cggctagaat accaggcatt
     1201 gcagccggca gcactatttt aaaaatcgtc cttagcttac ctgctcctaa gccaaggcta
     1261 gcctgacgca agtgatcact aacagagagg agcgcttctt ctgttgatcg aatgataact
     1321 ggcaacacca tgattacaga cgtcagaata cctgataaaa gagaatattg caggccgaaa
     1381 aaaaccacaa agaacagcat gccaaaaaga ccaaaaacaa tcgaaggaat ccctgatagc
     1441 gtatcagctg caagacgtat tgcccttacc catagtgagt cctgcttagc gtattccaca
     1501 agatagaagc cagcaaagac accaatgggc aaggctagca ctaaggtgcc taaaactaga
     1561 ctaacagttg agataatcga cggcattaga gaaacattgt cagaggtata ggtccatgaa
     1621 aataaggata acgacagact aggcaagcct tttatcagca taaaggcaat aatcaaaaat
     1681 aaggagccaa aggtcaatag cgacaaaaga tagaccaggg cttttagtaa atagttagtc
     1741 atgagctgat tttcctttca cataagcaaa gcaagcatta atgatgagaa taaagccaaa
     1801 gaggacagcc gatgttgcaa tcaaggcctc tctatgctga ccagaagcat atgccatctc
     1861 taggacaata tttgtcgtca tggttcttgt gccctcaaat aatcctgatg gcagcacagg
     1921 ctggtttcct gctaccaaaa taactgccat cgtctcacca atggcacgac caaatcctaa
     1981 aataagagcg gaaaaaaggc cggatttggc tgctggcagg atcactcgaa aaatactcct
     2041 ttcatgactg gctcccagtg caagactagc tgaataataa gcctttggaa cagctctgat
     2101 agcagactct gaaagactga taagcgttgg caaaatcatg attcctaaga gcaaggaggc
     2161 agtcagcaca ctcatgccat taccagcaaa gctcctaatc caaggcacta gcacttgaag
     2221 accaaaaaag ccataaacga tagacggaat ggctgccatc agattaacag ctgactttaa
     2281 aaagccatag catgctttag gacaatagta aaccataaaa actgaggtca atatacctgt
     2341 tggcacacca atcaccattg caccaagtgt gatgacaaaa gaccctgcaa tcatcggcaa
     2401 aataccatag cttgccggct gatttgacgg tgaccaatca tttcctagca aaaaggctct
     2461 cataccatac ttagcaataa agggaaggcc attactaaaa ataaagatac agattaaaca
     2521 aatagcaata attgccatcg ctgcactgag aaagaagata actttaaaaa aatcctcttt
     2581 aaaggcttgt ttattcactg atgatccttt ctaagaaagg aaagcaagaa caaaacacct
     2641 cttctttgcc ttccttctaa tcgttcttta tttgactttg tcccagcttg ttagcttgcc
     2701 gctaaagaca tcagccagca catctatgcc aatattactt accttattgt ccttgtgaac
     2761 aatcactacg ataccatcaa gggcaatcgc atcatcaatt aagcccttgc tctcctcagt
     2821 tgttaggtca cgagaaacca taccgatgtc tgctgttttt tccttgacgg cggtgatacc
     2881 tgctgatgag ccatttgagg taatatcaat gctaatggct ggattttctt tcttgtatgc
     2941 ttctgctaat ttttccatca agggtgaaac tgaggttgag cctacaattg acagcttgcc
     3001 tgataagccc ttactgctat aggctggcgc gtctgttttt gcttcgatca atcgattgtc
     3061 tctaacaatc tcctgcccct gctttgagtc aataaaggtg ataaaatcct taccaactcc
     3121 tgataggtct gaggaccata caatattaaa gggacgctgc agagggtatt tcccctctaa
     3181 aatagtctca cgactagcct ttacgccatt tacctttagg gctgcaacgt cgctatttaa
     3241 ggaccctagc gagatgtagc caatggcacg actatttccc ttaacagagg agatgacccc
     3301 ttctgtgcta ttttggataa tagctgtttt tgctgtttgg tcaatctctt tgtcaccgtc
     3361 cttttttaga atgcctgtca tttcggtaaa ggctccacga gtacctgagc cattttctcg
     3421 agaaacaagg tcaatcctgt ctgctgcttt tccagcatca gcactgttat tgccacaggc
     3481 tgcaagacct aagcctgata agccaatagc tgccatgatc agcatttttt tgattgtcat
     3541 aagaatcacc cttatctttt atgatattgt gttgtaggct tgctacacct atagcttatc
     3601 aggtctttgt aaaggtttat ccctgattaa tgtaaagatt ttgtaaaacc taaaacagcc
     3661 actaccaagg ctggccttaa gtagctggta gtgactgttt acttgttgat agcttctggt
     3721 aagaataagg taaattggct gccctctcct agctgacttg tgactgttat ctgaccgcca
     3781 agaagctgac tcagctcctt tacaatggct aggcctaggc ctgttccacc actttgcctg
     3841 ctacgtccct tgttaacacg ataaaagcgc tcaaaaatac gatctagctc aatttggcta
     3901 atgccaatcc cagtatctgc aactgtaatg gcaacaccac cagcaaccct ttgactggat
     3961 agctgaattc tgcccccatt gtctgtatac tgtatcgcat ttgataagag atttaacatg
     4021 atctgcgata agaggtattg atcagatgtc acaacaatcg aatcctccaa tgcatagctt
     4081 agctcaagct gcttttgctc tagctgtggt ctcatgctct gacctgtata cagcaggaag
     4141 ttcctgagct gaaactctgt caggtcaagt ggtgtcttgt tagccttgga taaggtcagc
     4201 aggtgctcaa caatacgttc tagacgcaag ctttcattgt agataatgtc taaaaagtct
     4261 tcttttaggc ttgtttcatc gtcaggcatt tccttaatcg tttcagcaaa gcccttgatc
     4321 gatgtaaccg gtgttcttaa ttcgtgagaa gcattagcaa taaactccaa atttagcctc
     4381 tcataatgac gaatggccgt cagatcatat aagagcacta aaatctcctt gacaacatgc
     4441 gactggttaa agataggcac aagggtaacc tccaagatca aatcaccatc atgtaggcct
     4501 gttaattcct tctttaatgt ctgcttttgg tcaaagactt gattaactaa ggctatcaga
     4561 tccattcgtt taagatcctc caagaccaca aaaggtggct tagcctctgg aaaataagcc
     4621 ggtaaggatt tgctggtcag caacagctcc ctttgattgg agactaaaag catgcccatc
     4681 gtgagatgag aggttacagc ctccacattt tttgataagg cttttagcct tgcttccttt
     4741 tgtaataggt cactttttag ctctgtcagc tgcttagcat aagcacttaa atcagcctgc
     4801 cccactagga gaaaatggtc actagctgtc aaaagatggt ggtgcaaggc tctgaattca
     4861 cgctcccatc taaatagcat gctcaagaca taaaagctag ctacgagacc agtacacagc
     4921 actactagag tcagcacctg atgcggccct tgccaaatca gaccaagagc agccagcaag
     4981 caaagcccta gcagcatgct caaacgccta agatgtccta tcattcttta gctccttaaa
     5041 tttgtagcca tagccgcgaa tggtttgaat atactgaggc gccttaggat tgtcctcgat
     5101 tttttctctg agcttgccaa tatgaacgtc taccagacgt gtttcttggc caaagtcata
     5161 accccagata cgctctaata gccgctcacg cgtcagggtc atattagggt gcttcatgag
     5221 atagagcagt agctcatatt cctttggggt taacggcaat agctccttgt ccttatagac
     5281 ctcatgtcgc tctgggtaca gacgcaattg actcatcgta taaaaaggct cacgacgctc
     5341 ttcaccatca ccagaaatct ctgcttcagt acgccttaaa atagccttga cacgcgctaa
     5401 taattctcta ggactaaagg gcttggtcac ataatcatct gcccccagct ccaaagccaa
     5461 aaccttgtca aattcatcac ttttagcaga aaccatcata attggggttt tgcttccctt
     5521 agcacgaagc cttttgcaga cctcgatacc gtctaattgc ggcagcataa tatctaacac
     5581 aataaaatca taaggttctc tttcagctaa tgccaaggca gtacggccat ctgttaccat
     5641 ctctgtcaca aagccctcct tggccaagtg ataatccagt agccttaaga taggctcctc
     5701 atcatctact aataatactc gttttgtcat ttcatagctc ccatcagcca cattatatca
     5761 tatttgtcag tcaatctaat gacacactgc ttgacggcct gaagcctaaa atcaatcaga
     5821 agataaaaag atgttttagc tttggcttta ccgtcaaatg attgtataat agagctatat
     5881 tgattgaaag aaggtatacc tatggcaatt actcataaga aaaatgacca gctcgaaaag
     5941 atgatggcag gctttgcgtc tatcccagat tttgataagc ctttagagct taaccaagat
     6001 ggaaagctag tcactgaaaa accaaagcca caagtcaaga cagctaagca ggactagccc
     6061 ttattggcgt cgttaacata tagaaaggat acggtgaatg tcgctttttt caaatctgcc
     6121 acccagcgtg cttcaatggt ttgcgatttt tctatccatt atcattgaag ccctgccttt
     6181 tgtattttta gggactattt tatctggctg tattgaggtt ttcgtcacgc ctgatttagt
     6241 tcaaagatac ctccctcaaa ataagtggct aagaatttta tttggtacct ttattggctt
     6301 tgtttttcct tcctgtgaat gtggtatcat tcctattatt aatcgttttt tagaaaagaa
     6361 ggtgcctagc tacactgctg ttcccttttt agcaaccgct ccaattatta atccgattgt
     6421 tttatttgct acctactctg cctttgggaa ttcgctgcgc tttctcatgc taaggctttt
     6481 aggcgccatt ttagtggctg tcagccttgg catcatgcta gccttcattg ttgatgagaa
     6541 cattctcaag gaatcaaccc agccggtgca ttgtcatact tacagtcacg aaagcctgcc
     6601 aaaacggctt tacttggcac tggctcacgc tattgacgaa ttttttgata caggaaggta
     6661 tctagtcttt gggaccctga ttgcttcagc catgcagatt tatctgccaa caaaggtgct
     6721 gacagcgatc ggacatagcc ctttgacagc catcttagtc atgatgctct tagcctttat
     6781 cttatctctt tgcagtgagg ctgacgcctt tattggagct tcgttattgt caacctttgg
     6841 agttgctcct gttttagcct ttctcttaat cggccctatg gttgacatca aaaacctcat
     6901 gatgatgctc aattccttta agggagcctt tattgttcaa tttatcagtg tatcagctgt
     6961 gatgattacc atatattgct tacttgtggg ggtgctgtga tgattcgctt tttaatttta
     7021 gcaggctatt ttgagttgac catgtatcta gagctatctg gcaagctaaa tcaatatatc
     7081 aatattcgtt acgcttactt agcctatatt tctatggttc tatcctttat ccttgcattg
     7141 gtgcagctat acacttggac taaaaacatc aagctacaca gtcatttaaa aggtaaggtc
     7201 gctcagctga ccagtcccct tatcctggtc tttcctgttt tggttggctt gttagtacct
     7261 acagtcagct tggattcgac gaccgttgcc gccaagggct atacctttcc attagccgca
     7321 ggcgcttcaa aaacaggggt cagtgatgat ggtactacta ttcaatacct aaagccagac
     7381 accagcctgt actttaccaa atccgcctat caaaaggaaa tgctcaatga actgaaaaaa
     7441 taccaaggca aatcagccat caccattacc actgacaatt atatggaggt aatggaatta
     7501 atctaccttt acccagacga attcgttgat cgtacgattc agtacactgg ctttgtctat
     7561 aatgagccag gacatgacag ctatcaattc ctctttagat ttgggattat ccattgtatc
     7621 gctgattccg gtgtgtatgg gcttctgacc actggtaatc aagaaagcta tgccaataac
     7681 acttggctga ccgtcaaggg ccagctgcac atggaatatg acaagaccct agagcagcag
     7741 cttcctgtcc ttcaaatcga ggaagcacac caagccccag agcctgataa cccttatgtc
     7801 tatagggtat tttaacaagc attaagcctc cacacctatg acacaggtct atggaggctt
     7861 tttgttaggg gacagtacaa agacgtaatt gagttcgttc catttaaatg aaatggctaa
     7921 aagccgtata gcatcagcct tttaaaagac gtgtgctata cggctttgct attgttggta
     7981 aagcctttga ggctactttc tagctctcct cagacaggct acgcccattg gtctcaatga
     8041 ccctttgata ccaagcaaag gattttttct tgtagcgtgt caaatgacca ctgccatcat
     8101 catgtcggtc gacataaata aagccataac gcttacttag ctgagcagtc gacatagaaa
     8161 cacaatcaat acagccccag gaggtatagc ccataatgtc aacaccgtcc tcaatagcct
     8221 tagcaacctg caataaatgc tgcctcatgt aatcaatccg ataatcgtcc tgaactgtcc
     8281 agtgaccatc ctttgtctgt actagcttat ctttggcgcc aagcccattt tctacaataa
     8341 agagaggaat ttggtaccta tcatagtaat cattcaaggt tatgcgaagg ccaattggat
     8401 caatttgcca gccccattcc gaagagggca gatgaggatt aaccaagcca cctaaaatat
     8461 tgccctcccc tcgttgataa tgatccgggt gatgagactg agtcacactc atgtaatagc
     8521 taaaggataa aaagtcaacc gtatgctgcg ccaaaagctc actgtcgccc ggttcaaatt
     8581 gaatgtcaat gtgctgctcc ttaaaaaagg atttggcata ggaagggtat tttcctctga
     8641 cctgaatatc tgagaacagg agattacgtt gctcaaactg cttcgcagct aaaatatccc
     8701 tcggatcaga ggtcattgga taggctggca tagccaaaat catacagcct attttaaaag
     8761 cagggttaat caatctagca agccttgtca cactagcaga cgctactaat tcatggtgaa
     8821 tcgcttgata aagctcctgc ggagtcagct tttcctttgg tgtcatgata gcaccactgg
     8881 taaaaggcat atgcaggatt gaattaacct cattgaaggt taaccaatac ttaaccttgt
     8941 tcttgtagcg ctgcatgaca gttgtcgcaa aacgttcaaa gaagccaacc atacgacggt
     9001 cagtccagcc attatagacc ttagctagat gcagtggggt ttcgtagtga gatagggtca
     9061 ctaaaggctc tatgccatgt gctatcagct catcaaacaa atcgtcataa aattgtagcc
     9121 ctgcttcgtt aggctctgtc tcatcgccct gaggaaaaat acgagaccaa gcaattgatg
     9181 tccggaaaac cttaaagccc atttctgcaa agagcgccac gtcctccttg tagcggtgat
     9241 aaaaatcgat ggcctctagc ttcaaattag ctgctgttgg ctcagctgta tagtctccta
     9301 agcccccttc tggtaaaaca tcctgaaccg acaagccttt gccatctgtt aaataagctc
     9361 cctcaacctg attggcagca actgcccctc cccacaagaa atcctttgga aaacaaacca
     9421 tattatctcc tccttcaatt catctcttta gagaataacg agagcaacat catgctgagt
     9481 gatatgctcc ttgttgtcat taacaatgat ttcgagctgc tcagagctat tggtcaccac
     9541 aaatggagtc actaaagaat agcccttaga gccaatcaat tcaagatcta tacgtagcag
     9601 cggctgcccc tgcttaacag tatcaccagc cttaaccagc tgctcaaagc cctgtccttt
     9661 tagctcaacc gtatcaatac caacatgaat taagacgtca actcccttgg cgttctttaa
     9721 agcaatagca tgctttgttg gaaaaagggt gataacctcg ccatcaaatg gggcatagac
     9781 atattcctca ttaggtaaaa tagccagccc ctctcctaaa agcttagacg aaaaggtttc
     9841 atctggcacc tctgataatg gaagcactgt gccaaccatc ggagcataaa tagattgctt
     9901 tgctgataag ccacttttta ctggcgtgct atccgagtca gctgacccct cctggtcaac
     9961 ctcctcatca atgccaaaaa accaggttaa tgtaaaggtt agagcaattg ttaagcccgc
    10021 tgcaattaag gcattggtaa aattagcaga gctagtcggg ctaatgtatt gtggcaatcc
    10081 aattagtgat ggcaccacaa aagtataaga ggctatatta acaaagccaa tataggcgcc
    10141 cacaaggcca ccagaaatca ttgcagcata gagcggcttt ttaaacttta gagtaatgcc
    10201 ataaagagca ggctctgtaa ttcctgccaa taaagctgat aagcctgctg ctaaggcaac
    10261 ctgacgggtt tgcttttgct ttgattgaca tgctacagcc accgctgctg atccctgagc
    10321 taggttagag gctagcattg ctgggaggat taaaacatct ggagttgcta cagaggccgc
    10381 cagaaaaata ggagcaaagg cccaatgcat acccgtcata acaacaagcg gcataattgc
    10441 acctaaaata gcaagagcca gccaaggagc aatatggtaa atcgctagca ggctattaga
    10501 caagccctgt cctataataa cacccagagg tccaataaca actaaggcta gaaagcctga
    10561 aataaaaata atcaaggtcg gctgcaggaa gctcttcatc acactcggta caaaacggtt
    10621 aacctctcgc tcaatgtatt gcatcaggta aaccataatt aaaatcggaa taactgacgc
    10681 accatagcta gcaggtgtca ccggcgctcc aaacaaagcc ataggtttac ctgtagctac
    10741 catcgtaaca aaagctgggt gtagtaaaat ccctgcaaca gttgctgcta atacaggtgt
    10801 gaccttaaag cgtgccgcag ctgaatatgc aatcatgatt ggcataaaat aataagcagc
    10861 atctccaaaa aaattaataa aagcaactgt ttgagagtcc gtacctgcta gaccaagcat
    10921 aggcaccaag atcccaacca cctttaacat accgcctccc agtaaggcag gtatcagtgg
    10981 agtaatcaca ctagctatcg tttcaatcaa cccttcaatc atagactgct tttgaccagc
    11041 gctagagctc atatcagttt catgaaactg tcctagggtc ataaatgcct tataataatt
    11101 gttaacatcg tttcctaaaa taatttgata ctgaccgttt tggcgcatga ctccaatcac
    11161 attaggaata agtttgattt tttgatctac cacttgttta tcatctttca aaaccaagcg
    11221 taaccgcgtg atgcagtggg ttacctcttg aatattctgc tcaccaccaa ctgcttcaaa
    11281 aatggccttg gctgtttctt gataagtcat ttcattactc cttcacattt ttgactaaac
    11341 gtttgatatg aaccgttaaa tacaaaagct cactagagct aagctgataa tggtatgctt
    11401 ttttcatgtg atggctaatt tgcctaacac agtgatattc ctctgggtat ttatccttaa
    11461 ccatcagcag caaatcagtc tcgtcatcat cataagccat gcctgataac acgcgctgag
    11521 caaatagctt cacatgagtg ataaagcgat aataatcaat agagacttca tcaagctctg
    11581 tcttaaaatc agccttgacc ttctgttcaa tgtaagacac aatttctgtc attcgatgag
    11641 gctccttgaa aggattatca aggctcgcgt tgacaaagtg catcgcaata aacgaagctt
    11701 catctacagc cagagcgact cctagctcac tggcaatgac ctctaaggcc ttaacgccaa
    11761 tcgcatattc atcaggataa taccgtctaa tctcccagcg caagggatca ctaatgatca
    11821 tcccctgctt atgtctttca atagctgaat gaatatggtc tgtcaaattg atatagagta
    11881 tttcatctaa atttttaccc agcttaattt tccctagatt aataagcctc tctgagcaag
    11941 caaccacctc ttgcggaaca gcaataaata attcagtaaa acggttcata ttgtcactat
    12001 tttttaaaac aaatgacgct tcgatagctt cactatcgat atggtcacca attcttttct
    12061 taaaagcaat cccctttccc atcaaaagaa tatctagccc ctgatggttg gtcgaaatcg
    12121 ctgcattatg gtttaaaacg cgtttaataa tcataaaagt cctagtccct cattgcttca
    12181 caataaaaaa tgacctatcc acagcatgct aaaaggccac actggaatag gtccctgctc
    12241 acaaaactgt gataacatcc tttaatattc tgattcattt gtcattagca cgcttaccct
    12301 aagtaatcac atctaataac gttttcattt tatcatctcc taaaggtcct gtcaagcgtt
    12361 ttcaaaaggc tgtttgacat ttgcctctaa acgaaccccc tcattctctt tggccaacag
    12421 ccgataatct gaggctttcc tcttaaagta tgccttctaa tagtcccttc ataaagtcct
    12481 cagagtgaaa ttcaccgata tcatcaatag cctcaccaaa gccaatcagc ttcactggga
    12541 tatccaattc ctgacgaata gctaggacaa ttcccccctt agctgtaccg tcaatcttag
    12601 ttaaaatcaa gcctgtgagc ggtgtgattt ttgaaaactc cttagcctga ctcagagcat
    12661 tttgccccgt tgaggcatcg agcgctagca gggtttcgtg tggggcatca ggtatgacac
    12721 gcttaatgat tcgtcctatt ttttcaagct ctgccattag gttgtcctta ttttgcaggc
    12781 ggcctgcggt atcaatcagg agaatatctg ccctttcagc aacagccctc tcaacgccat
    12841 caaagaccac agaggccgga tctgcttttt cagggcctgt aatgaccggc acatcaaccc
    12901 gtcgtcccca ttcaaccagc tgggcaaccg cgcctgctcg gaaggtatca gctgcaacaa
    12961 gcataacctt ttttccctct tgcttatacc gataagctag ctttccaatt gatgttgtct
    13021 taccaacgcc attcacccca acaaagagca taacggtcaa gccaggctga taatgaatcg
    13081 cttcattgta gcggccatcc ccctcataaa tagccactag cttatcaatg ataagacgct
    13141 ttagagcctc tggcttttta gcattttcaa gcttagcctc atagcgcaat tcttcagtca
    13201 aggttgtggc aacatgaaca ccaacatctg agagaatcaa aagctcctct aagtcctcaa
    13261 agaagtcctc gtcaacacgt ctaaagttag caaagaagct gttcaagcgt gctgaaaagc
    13321 ctgtacgggt tttctttaag ctgcgcttgt atttttcctg atcagattca gctgataggg
    13381 tctcttgctt ttggccttcc tcagctggct gatcagctga accagcaggt gcttgagctg
    13441 ctacttgata ctcagcattt gtctctgcct gatcttctgt tgatgcgtct gcgctctcgt
    13501 tactatgctc tgacttagcc ctatcatgct tagcctcctc catagcctcg tgctggctta
    13561 ggctctcacc tgcctgatcc aaggtcttgt catcagtagc tgctaactct agctccggct
    13621 ctctttctaa aagaaaagct cctctagctg ctggatcaag cccttcagct tgctctgaag
    13681 cagcctcgtc tgagagctca gcctgtttgc tagtgtcatc ggtcctagag accacatcag
    13741 ctgccactgc atgagcattt gtatctgata aggcctcctt ttcagactca atcgtatcct
    13801 ttgacgttat gtcctccgac aatacctctg tagtggcagc ctcttgctca gcaaccttag
    13861 tcttatcctt ttttccaaat aagcgttcaa ataatcccat tagccttcct catttaaaat
    13921 atatttccaa atagcctcag ccacacctga ttggtcattg gttagggtag tcactgcatc
    13981 tgccacttcc ttagcctgat caaccgcatt ggccatagcc acaccaagac ctgcccattg
    14041 tagcatgcta aagtcattgg cctcatctcc catcgccatg acatgcttgg cctccaagcc
    14101 caagtgctga caaagcaggt ccaaaccaaa tgccttatga atccccttag gcataatctc
    14161 aaagatgatg tctcgtgatt taaaggcctc aaaatcctca aagatagtct ttggaagcct
    14221 tgcaagctgc tgatccaaga cctttggatc cgtcaccgta acaattttat tgtatgtgat
    14281 gtcctttggc agctcagcaa atgatttaag gctaacaaag ttcagcaagg gacttgccaa
    14341 gtgatactga gagcgtctgc catcattgcc tgatagacta taaacagtac catcactgat
    14401 aacatcagta ggtaagccaa ccgctgccaa ctgctgatga atgtcataaa cctcagcaag
    14461 gcttagagcg cttttatcta aaatatgacc agtatttcgt tgaaccagac cgccattaaa
    14521 ggtaatgcta tagttctctt cacctagcaa atccagctcc tcaagcaaat ttccgatagc
    14581 cttaagagga cgtccggttg tgataacaac cttaactcct ttttccttag ctgctgctag
    14641 agcttttttg ttctcatcac taacgatttt ttcggtatta tagagagtcc catctaaatc
    14701 tagagctaaa agctttatac gcgtcattta caccaatccc tccaaataag ttaacactgc
    14761 tgagtcatta caatgaccaa taacctgatc agaaatcgct ttgatttcag gccttgcatt
    14821 ttcagtagca atagcctgcc ctgcaaagga cagcatttga taatcattta gattatcgcc
    14881 aaaggcaatg gtcttttccg gtaaaatgcc taggtgctga cacagctgat ccatgccaaa
    14941 gcccttatga acctctttta ggataatatc aatcgaatca aagccagtcg tcaccgcaga
    15001 agcataggac agctcctgat ttagccagtc actgccagct aagactgttt ctcctgtaaa
    15061 ggtcgttgag gctttaaaaa cagtgtcatc aacaatatcc tgcagacaat caataagctg
    15121 aacattttca taataataat gcattttttg gatataatcc tccgtagctc ctttgagcac
    15181 ataggctgcc ttttgccctg aaaagaggat cccagactga ttgtaataag gattggcaag
    15241 aattttctct acaatgtcat gacactgctg cttggtcatg acatcagcaa aaagaatgtc
    15301 cctcttgtat tgcaccacag acccattctc agcgataatg gcaatgtcat ctaaaaaagg
    15361 ctcaaacaag tgatcaatgg ctaaaagcga acgcccacta gaaactgtaa agagaatccc
    15421 tttttctctt agcttaggca acagagctgc caagcgctcc ttgtcataag ttccgtcctc
    15481 tcttaaaaag gttccgtcca tatctgttgc tatcaattta accatacaat ttaaccattt
    15541 cctttttagg gagatactga ttcagctatt cagctctccc aaaaatctct ttttccatta
    15601 taccatatct aaacaaaaag ggcgtgcctg tcctaacacg tccttgtttt aaggctttat
    15661 aatttctgta gtgggtaact ccactgtgga gattattgag cccttattcc aaggctttct
    15721 ttatgttcta ttgtatcaat ttccttattc caatttctgt tgcaattaac tttaacatac
    15781 aatctaacca tttcactttc aagggagtgc aaaacccgag tggggtgtgc aactcaaatc
    15841 ccagtataac tcctttcgtt ataccacagg tagaccaaaa aagggcgtgc catctgacat
    15901 acccttgttt taacagtcaa tctgagctcc gtttttaaag gctaaacttc tttatctcca
    15961 tactctcaac gcttatttgc cataattctt aattgaagcc cgtcactaag ttttcttgtt
    16021 actaaagagt tgagtaatga atctatctag actgatgatt tttctcctta aaagcttcat
    16081 atagtttttt atataacgct ttcttttctt ttttctgagc attaaactct tttttaccgt
    16141 aatcaaaatt tgctaccaca aaccccttgt tattgttaga aaaatcaaaa aattccattt
    16201 cgattaattt gttattctta gaatcttcta tagtattctc taaatgattg ttgaattgtt
    16261 taacatcttc ttcactaact ccaaaaccca tagcagctcc gtctgcaatg atgtttgaaa
    16321 atatttcttc tgaagatgct gcttctttta cccttattag gtatatggct tcttctgttt
    16381 ctaattgtct tactttattc catttttggg tatcactaga agagatcgta tagactgtta
    16441 aatctaccgt aggtttattg ggattttctt tttttattac ttgttttccc actaagaaaa
    16501 ttgcgagtat tccaattaat aatatcaacg tcatataagc tttctttttc atatctcact
    16561 ccctatatct ttcaaatcaa tgataacatc aaccttatta tatacagctg gatcatgtgt
    16621 tgctataata acatatttat tttcggctgt ttcactcaat aataaattaa tgatttcttt
    16681 tccaatctca ctatccaaag ctcctgtagg ttcatccgct aaaataattt tacgtggctt
    16741 cattaacatt cttgcaatag ctacacgctg aacctgtcct ccagataatt catatatttt
    16801 ctgatttaaa tagtcattag aaagtcctac tttttcaagt acatcagcta
//
LOCUS       DARYXS010000042        16775 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.043, whole genome shotgun sequence.
ACCESSION   DARYXS010000042 DARYXS010000000
VERSION     DARYXS010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16775
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.043"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            39..2030
                     /gene="uvrB"
                     /locus_tag="TV193_001120"
     CDS             39..2030
                     /gene="uvrB"
                     /locus_tag="TV193_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEL1513322.1"
                     /translation="MIDKRDFKAFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEVFPASRDEHAFR
                     IEFFGDEIDRIREIESLTGKVLGDADHLVLFPATHFVTNDEHMEQSISKIQAELADQL
                     KLFEAEGKLLEAQRLRQRTEYDIEMLREMGYTNGVENYSRHMDGRSAGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDKARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRVERG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNADGHVIMYADRMTDSMQ
                     RAIDETARRRAIQMAYNEEHGIIPQTIKKDIRDLISISRAVEAKATEAETNYESMTRS
                     ERQEAIKQLQKNMQEAAELLDFELAAQLRDLILELKAMD"
     gene            2369..2512
                     /locus_tag="TV193_001121"
     CDS             2369..2512
                     /locus_tag="TV193_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEL1513323.1"
                     /translation="MLKNKSRLRAIFVFVGKIALFYVILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            2524..4062
                     /gene="dltA"
                     /locus_tag="TV193_001122"
     CDS             2524..4062
                     /gene="dltA"
                     /locus_tag="TV193_001122"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEL1513324.1"
                     /translation="MVNDMIETIEYFAQAQPDFPVYDCLGERRSYGQLKEDSDSIAAL
                     IESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPS
                     LIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPK
                     GVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLNDDFCQEKMPRLTHFYFDGEELT
                     VSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYI
                     IDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTED
                     NVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVV
                     LKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINE
                     VNHQ"
     gene            4059..5306
                     /gene="dltB"
                     /locus_tag="TV193_001123"
     CDS             4059..5306
                     /gene="dltB"
                     /locus_tag="TV193_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEL1513325.1"
                     /translation="MTTLFHHIPYMEPYGNPIYFVYLIIAFLPVIIGIFKQRRFSTYE
                     SFVSLIFILLMFGGEHYQQLLAFLAYLIWQTISVLAYKHYRQKANAAWVFYLSILASL
                     FPLICVKVSLSLTRSFFSFLGISYLTFKSVGMIIEMRDGVLTDFSLKDFLRFMIFFPT
                     FSSGPIDRFRRFQEAYTKLPSRDVYLDMLNKAVMYLMLGFLYKHIISYCLGGLLLPLA
                     ENKALTVGGYFNKETIYVMYLYGLNLFFDFAGYSMFAIGLSYLLGIKTPENFNKPFLS
                     PNLKEFWNRWHMSLSFWFRDFVFMRLVHLLIKHKTFKNRNVTSGFAYLINMLVMGLWH
                     GLTWYYIAYGLFHGIGLIVNDAWLRKKKEINRRRKKQGLKPLFEGKVFHALSIVVTFH
                     VVLFSLLLFSGFLNELWFSRPLR"
     gene            5324..5563
                     /gene="dltC"
                     /locus_tag="TV193_001124"
     CDS             5324..5563
                     /gene="dltC"
                     /locus_tag="TV193_001124"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEL1513326.1"
                     /translation="MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVE
                     IESIFNIKVPISEFGREDWNTANKIIQGIEELQHA"
     gene            5556..6809
                     /gene="dltD"
                     /locus_tag="TV193_001125"
     CDS             5556..6809
                     /gene="dltD"
                     /locus_tag="TV193_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEL1513327.1"
                     /translation="MLKRLWLILGPLIIAFGLVCLTIFSFPTKLSYSLRQEKSNAVAI
                     NDSSFKNGLIKRQALSDPNYCFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSQYYGMQQISQEITGKKAVFVVSPQWFTPQGIDPGAVQLYLSNSQVIDFLLKA
                     KASHKESQFAAKRMLDINPGVAKSELLRKISQGKALSRWDIRLLKWQQELSLREESLF
                     SFLGRSTNYEDRILPRVKGLPKTFSYERLSELAARRAKEGTSNNRFGIKNAFYSKRIA
                     PQFPLYKNFQCRNNYTVSPEYNDFQLVLSEFAKRKTEVLFVITPVNQAWANYTGLNQR
                     RYQKAVRKIKHQLTSQGFTRIADFSRNGGDKYFMEDTIHLGWNGWLAFDKEVVPFLED
                     QTPPSEYQLDPYFLSKDWADRTAGF"
     gene            6843..7817
                     /locus_tag="TV193_001126"
     CDS             6843..7817
                     /locus_tag="TV193_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1513328.1"
                     /translation="MLMSIIVILLILAIAVLVIEYGQKRSFSSWLLEKMFDYRKYKLS
                     KKADDYEGIETQRRRRIPYHLDNPEAVLGIPTTEYTIDGMQVFVINDQDSQDQPVIYY
                     LYGSVYLRRPETFHFKTIKHLIHLTNAKLVFPNFEKAPYVTYKEIYPKLAKTYQELCL
                     ANGAAKVSIIGDSSGGGMALALAQYLRDTQTAPQPKQLILLSPWLDVSFANQDYKHFE
                     AVEAYLDARRLRDIGELWAGSPEEMRSPYVSPLYGDYHDLPKIVTFVGTKEIFYPDIM
                     TLHERLMEQGHLNQLVIAEQMIHAYAIFPIREARQARKQIAELILKKE"
     gene            8358..9617
                     /locus_tag="TV193_001127"
     CDS             8358..9617
                     /locus_tag="TV193_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1513329.1"
                     /translation="MAWDWKKAGVVGVVSLASIMVLSACSGGHQKEAKQKDDNTIVVS
                     VDEGYADYIKEIKTAFEKDNKVKVKVKKEGMIDTLDKLSTDGPTGASPDVFLAPYDRV
                     GGLGSEGQIAEVSLGNADQFDDTVKKLVTINGKVYGAPDVIETLVMYYNKDLVSEAPK
                     TFTDIEELNKDPKFAFASEDGKSVGFLAKWTDFYYGYGLIAGYGAYVFGDKGTDPKDL
                     GIGNAGAIEGLDYAKKWYSVWPQGMQDTQKAGDFITEQFTSKKAGVIIDGPWAAASFK
                     EAGVNFGVAQIPSLPNGGSYQAFGGGKAWVISNYSKNKKLAQQFLDYVTNEKNQKAFY
                     GKTQEIPANLAARSYAAEQGNELTKAVIGQFSNAQPMPNIPEMAEVWGPGANMFFEVA
                     AGKKTPAKAAKEAAKTIQEAIAQKYTE"
     gene            9790..11490
                     /locus_tag="TV193_001128"
     CDS             9790..11490
                     /locus_tag="TV193_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEL1513330.1"
                     /translation="MNTAGILHIPDSRYCFALSTKELVIRLRVAKEDNDIAVTLVYGP
                     KYHYHEYQKELAMYAAYTDHTHTYYEITLSLDDVRLAYIFKLEQSGHTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQTVPWVHNAVFYQIFVDRFHRGDFEKDDSYINMAW
                     LDRPTPNSFAGGDLKGITDKLEYLEDLGINVIYLTPIFKSISNHKYDISDYYAIDPMF
                     GTSLDLQQLINEAHQRGIRIILDAVFNHASSDCEPFQDVLAHGSASSFFDWFMIQGDH
                     PSVELANYETFADCHYMPKWNTSHQAVQDYLIEIGLYWITEYHIDGWRLDVSDEVSHD
                     FWRRFRKAVKAVKSDAILIGENWHDAYPYLQGDQYDGIMNYAFTKACLDYFAFDAISS
                     QEMAERLSHILMRNTWQVNQMNLNLLDSHDTHRFLTQVNGSKDKLLAGLALLVTFMGI
                     PCIYYGTELAMEGGYDPDSRRSFNWDSSTWDMSFWNQVKDIISLRRHAVIQFGSISIT
                     SHDDCLCVKRELNGQSIRLLVNNGVKPYPIEKGGSVLVSNGVDKETFELLQNGFVVSY
                     "
     gene            11519..13651
                     /locus_tag="TV193_001129"
     CDS             11519..13651
                     /locus_tag="TV193_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HEL1513331.1"
                     /translation="MKRITLTCRKALTVAMAAVTLAMSTNSVFAIENTAVSNKADFST
                     DTIYQIVTDRFHDGNAANNGNTDVFDKNDPKKYHGGDWAGIIKKLEDGYLTNLGVSAI
                     WISSPVENIDTIDPSNGSAAYHGYWAKDFFKANSHFGTMEDFKKLIQVAHGKNIKVVI
                     DFAPNHTSTAEYNGLTFPEDGALYKDGQLVGKFSHDDQKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNLNPTVDDYLKEAIDKWLEMGIDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFAFGEWFADGSFNDPLMTKFADTSGMSLLDFRFANSVRRLYSDLSAKMQDFYNMIV
                     ATEKEYKEVSDQVTFIDNHDMTRFATLVNHNQTAVNQAYALLLTSRGVPNLYYGSEQY
                     ATGANDPENRGDMPTFDKNSTAYQVISKLAPLRKKNQALAYGTTQQRWINDQVLVFER
                     KFGNDVALVAVNKDQTNGYTISGAKTALPAGKYADELGGLLGGKELTVSADGNVEAFE
                     LGAGQVAVWTFKGQHETPQIGDVDASFGVAGNTVSISGQGFGSAQGQLHFGDSKADIV
                     SWDDTLIQFKIPAVAAGNHDIKVTTSTGQSSSPYKAFEVLTDKQIPVRLVVNNFNTVL
                     GEQLYIVGDVVELGANDNHKALGPIFNATQSIAQYPNWFYDVNLPINKTINCHLVKKD
                     SSGKVLWTSPETYTIKTDSKAQTISLKK"
     gene            13727..15031
                     /locus_tag="TV193_001130"
     CDS             13727..15031
                     /locus_tag="TV193_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1513332.1"
                     /translation="MLKNEKMKNPQKAMWLSIIPGLGQLYNTQKVKGFILLLVFLGEL
                     LEAFFVGIPALAGLYSLGSVPMEDHSLFLLIKGAMQLILFALFLIFHLAAMRDARLVA
                     REINAGHSISLTLKEMVQSIYEKGFPYLLIIPAYLAMAFAIVFPVLVTLLIAFTNYDF
                     RHIPPYKLLDWVGIKNFKSILELSTFKSAFGSVLSWTLIWTLAATSLQIVIGIATAII
                     ANQSFVKCRRIFGVIFLLPWGVPAFISIMSFGNFFNDSIGAMNVQVLPFLEKFVPFAD
                     FGIIPWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQSIPADLYEAATVDGATALQK
                     FRQITLPMIFAVAAPTLISQYTFNFNNFSIIYLFNNGGPGTVGGGAGSTDILISWIYK
                     LTTQTSPQFSIASAVTLIISLIVISVSLITFKKFKAFDMEDR"
     gene            15032..15892
                     /locus_tag="TV193_001131"
     CDS             15032..15892
                     /locus_tag="TV193_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1513333.1"
                     /translation="MGRNYLPQSVKKKRLLAQLLTYSYLLILSIIILFPILVTVSSAF
                     RPGNTTAFSFHIDGPWTLSNFETLFQDTYYLRWYWNTLVVAFFTMLIQVTVITLTGYA
                     YSRYHFFGRQKSLVFFLVVQMVPTMAALTAYFVMAWLFNALNHYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVFPLVRPMVAVQALWAFMGPFGDF
                     MLAKFLLREQEHYTVAVGLQSFITNDARDPKVTLFAAGAILIAVPISVLFFFLQKHFV
                     SGLTNGGTKG"
     gene            15917..16747
                     /locus_tag="TV193_001132"
     CDS             15917..16747
                     /locus_tag="TV193_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein malA"
                     /protein_id="HEL1513334.1"
                     /translation="MTNDRFPISYTTIIFSPKMIFARCSAFLWWQNVILVIFLNALVL
                     MPITLHYASLKSYPLEHIVSNGLDSLTEKTYHALTQGTIWHDRYDGKTVLIEDTDAVV
                     AVLPTPEIVEELKKDQRSQLILTETSWILSFPDGQRLTAKVKGNKERLTRLTSLEAVK
                     AFVNQQWYNSNRAAVLAFLLLVASSVVYLGAGLVIGIGSLSLLLTRSARLFSLKSYSE
                     CLGLLVNCFGLPTLLAVLISFWVHNPIVIMNSQVFGTLLMLVLVFYKTQFRDEEQALA
                     "
BASE COUNT         4666 a         3040 c         3859 g         5210 t
ORIGIN      
        1 ttacaataga taagagataa gatattgagg accaataaat gattgataaa cgtgatttta
       61 aagcatttaa gctcgtgtca aaatatgccc cctcaggaga tcagccgcag gcgattgaga
      121 ccttggttga taacattgaa ggtggtgaaa aagcgcagat tttactagga gcaacaggaa
      181 cagggaaaac ctataccatg agtcaggtga tcagcaaggt caacaagcca acgttagtgg
      241 ttgctcataa caaaaccttg gccggtcaat tgtacggtga gtttaaagag ttctttcctg
      301 aaaatgctgt cgagtacttt gtatcctact atgactatta tcagcctgag gcctatgttc
      361 cttctagtga tacctatatt gaaaaagaca gctctgttaa tgatgagatt gacaagctgc
      421 gccattcggc cacctcatcg cttttagagc gtaatgatgt gattgttgtg gcttcggttt
      481 cttgtattta cggattgggc tcaccaaagg aatatgctga ttcagctgtt agcctgcgtc
      541 ctgggcagga gatatccagg gatcagttgc tcaatgccct tgtagacatt cagtttgaac
      601 gcaatgacat tgattttcaa cgtggacgct ttcgtgtgcg tggtgatgtg gttgaagtat
      661 ttccagcctc aagagatgag catgcctttc ggattgagtt tttcggtgat gagattgatc
      721 ggattcgtga aattgaaagc ctaacgggta aagtattagg tgatgctgat catttagtgc
      781 tttttccggc cactcacttt gtgaccaatg atgagcacat ggagcagtct attagcaaga
      841 ttcaggcaga attagcagac cagcttaagc tatttgaagc agaaggcaaa ttgctagagg
      901 ctcagcgcct gcgtcaaagg acagaatacg atattgaaat gctacgtgaa atgggctaca
      961 ccaatggggt tgaaaattac tcacgtcaca tggacgggcg ttcggcagga gagcctcctt
     1021 ataccctgtt agatttcttt ccggatgatt ttcttatcat gattgacgag agtcacatga
     1081 ccatgggaca aattaaaggc atgtacaatg gagacaaggc tagaaagcaa atgcttgtgg
     1141 attatggctt tcgtcttccg tctgccttag acaatcgtcc gcttcgtcgg gaggagtttg
     1201 aaagtcatgt gcaccagatt gtctatgtct cagcaacgcc tggagattac gagatggagc
     1261 agactgatac gattgtggag cagattatca gaccgacagg tctgcttgat ccggaggttg
     1321 aagtccggcc aagcatggga caaatggacg acttgcttgg cgagattaac ctgagggttg
     1381 aacgaggtga gcgcaccttt atcacaacct taaccaagaa aatggcggag gatttgaccg
     1441 actacctcaa ggaaatgggt gtcaaggtaa aatacatgca tagcgacatc aagacattag
     1501 agcgtacaga aattattcgc gaccttcgtt taggcgtttt tgatgtcttg attggtatca
     1561 atctgctgcg tgaaggtatt gatgttccgg aggttagcct tgttgctatt cttgatgcgg
     1621 ataaggaagg cttcctaaga aatgaacgag gtttgattca gacgattggt cgagctgcca
     1681 gaaatgctga tggtcatgtg attatgtatg ctgatcgtat gacggattcc atgcagcgcg
     1741 ctatagatga aactgctcgt cgtcgtgcca tacagatggc atataatgaa gagcatggga
     1801 ttattccgca aaccattaaa aaagatattc gtgatttaat cagtatttcc agagcagttg
     1861 aagcaaaagc aacagaagca gagacaaatt atgagtcaat gacgcggtct gaaagacaag
     1921 aagctattaa gcaattgcaa aaaaacatgc aggaagcagc agagctgctg gattttgaat
     1981 tagcagcaca gcttcgtgac ctgatcttag agttaaaagc aatggattaa gacctgataa
     2041 gctaagtctg gctgtataag ctaggctttt tatctgcttt tgagtttgtc ctttaggtct
     2101 gtcttatgat ctttggtacc agataaatga gtgatatctt gagcttgatc tacgcaagag
     2161 ctagtgcagc cactagcttc agactacttt aatgatttaa tgaaagattg attttgataa
     2221 gacaattctg atataatgta aagtagttgg caaaaataga aacattaaat aaattttctt
     2281 tttaataatt taacttttac cttgtcaaca aggctatttt cggatagaat ttcttagtac
     2341 attatttcac taatacaaga aggtaagtat gttaaaaaac aagtcaagac tgcgagctat
     2401 tttcgttttt gttgggaaga tagcgttgtt ttacgtgatt ttgatgctgc tcgtttattt
     2461 ttttggttac ctagggcatg gtcaaagtaa ttttatttat aatgaatttt aggagattgt
     2521 ctgatggtta acgatatgat tgaaacaatt gagtattttg cacaagcaca accggatttt
     2581 ccagtttatg attgcttggg agagcgccgt agctatgggc agctaaagga ggactcagat
     2641 agtattgcag cccttattga gagcttaaag ctaggtgaaa aatcacctgt tttagttttt
     2701 ggggctcaaa gctatgacat gctggcttcc tttgtcgcct tgacaaagac aggtcatgct
     2761 tacattcctg ttgatgttca ttcggcgcca gagcgtgtct tgtctattat tgagattgct
     2821 cagccaagtc ttatcattgc tattgaggag ctgccggtta gtattgatgc gattagggtg
     2881 gttagcttag cagagataga ggcagctaaa gcagccaagg cagcctttac catgaccagt
     2941 cctgtcaagg gagatgacaa ttattatatt atcttcacct ctggaacgac aggacagcca
     3001 aagggagtgc aaatttcgca tgccaatctt ttaagcttta ccaattggat gattgaggat
     3061 gctgagtttg ctattcctga gagaccacag atgctggctc agcctcctta ttcctttgat
     3121 ttgtcggtga tgtattgggc gccgacctta gctttaggtg ggacattgtt tgctttaccc
     3181 aaggaaatgg tttcagattt taagcgcttg tttagcacaa ttgcggagct gccgataggg
     3241 atttggacct caacaccgtc ctttgccgac atggcaatgc ttaatgatga tttttgtcag
     3301 gagaagatgc caaggctgac ccacttttat tttgatgggg aggagctgac agtatcaact
     3361 gcaagaaagc tatttgaacg ctttccagac gcacgcatta tcaatgccta tggtccaaca
     3421 gaggcaacgg tggcgttatc agcgatttca atcactaaag atatgataga gacttacaca
     3481 cgcttgccga taggctatcc aaagccggat tcgcctactt atatcattga tgaagctggc
     3541 aatgctctgg agccggggca acagggagag attattgtaa cgggtccagc agtttctaag
     3601 ggttatctca acaatcctga aaagacagct gaagccttct ttacctttaa tggcatgcct
     3661 gcttatcata cgggagattt aggatcattt actgaggaca atgtgttact ttatggtgga
     3721 cgattagact ttcaaatcaa atatgcaggt taccgcatcg aattagaaga tgtgtcgcag
     3781 cagctaaacc aatcaccgct ggttgaatca gcagtagcag taccaaggta taacaaagag
     3841 cataaggtcc aaaatctctt agcttatgtt gtcttgaagg acggggtgag ggagcaattt
     3901 gcgagagatt tggatattac caaagccatt aaagcctctg ttaaggatca tatgatggcc
     3961 tatatgatgc cgtctaagtt tatttatcgt gaaaagctcc cattgacacc aaatggcaaa
     4021 atcgatatca aattcttgat taacgaggtt aatcatcaat gacgaccttg tttcatcaca
     4081 taccttatat ggagccttat ggcaatccga tttattttgt ctacctcatc attgcttttc
     4141 ttccagttat tattgggatc tttaagcaaa ggcgtttttc gacgtatgaa agctttgtca
     4201 gcctgatctt tattttgctc atgtttggtg gagagcacta tcagcaattg cttgcctttt
     4261 tagcctatct aatttggcaa accatcagtg ttttggctta caagcactat cgtcaaaagg
     4321 caaatgcagc gtgggttttc tatcttagca ttttagccag tctatttcct ttgatttgtg
     4381 tgaaggtaag cctcagtcta acgaggtctt tctttagctt cttaggtatt tcctatttaa
     4441 ctttcaaaag cgttgggatg atcattgaaa tgcgtgatgg ggttttgaca gattttagtc
     4501 taaaggattt tctacgcttt atgattttct ttccgacttt ttcaagcggg ccgattgatc
     4561 gcttcagaag gtttcaagag gcttacacca agcttcctag tcgtgatgtt taccttgata
     4621 tgctcaataa ggctgtcatg tatctcatgc tgggctttct gtacaagcat attatctctt
     4681 attgcttggg tgggctgcta ttgccccttg ctgaaaataa ggctctgact gtaggtggct
     4741 actttaataa agagacgatc tatgtcatgt acctttatgg gcttaatctc ttttttgatt
     4801 ttgctggcta ctcgatgttt gcgattgggt tgtcttattt actggggatt aagacacctg
     4861 aaaatttcaa taagcccttc ttatcaccaa atttaaaaga gttttggaac agatggcata
     4921 tgagcctatc attttggttt agggattttg tttttatgcg attggtccat ctattgatca
     4981 agcacaagac ctttaagaat cgaaatgtga cttcgggctt tgcttacctg atcaacatgc
     5041 tggtgatggg actttggcat ggcttgacgt ggtattatat tgcttacggt ctgtttcatg
     5101 gtattggctt gattgtaaac gacgcttggc ttcgtaagaa aaaggaaatc aatcgtcgtc
     5161 ggaaaaagca agggcttaag cctttgtttg agggtaaggt atttcatgct ttatcaatcg
     5221 tggtcacttt ccacgttgtc ttgttctcac ttctgttatt ctcaggcttc ttaaatgagc
     5281 tttggtttag cagaccgtta cgttaaaaaa ggagagtata aaaatgtcta ctaaagaaac
     5341 tgtaattgac ttatttgatc gcttgtttat ggaagacgta tcagatatga tggacgagga
     5401 tttgtttgat gctggcgttc ttgatagcct aggaacggtt gagctgattg tagagatcga
     5461 atctatcttt aacattaagg tgccaatttc agagtttgga cgtgaggact ggaacactgc
     5521 caataaaatt attcagggca tagaggaatt gcagcatgct taaacggctt tggttaatcc
     5581 taggtcctct aatcatcgct tttggcttgg tttgtcttac catattcagc tttcctacta
     5641 agcttagcta ttcattgcgc caggaaaagt caaatgcagt ggcaatcaat gatagctcct
     5701 ttaaaaacgg cttgattaaa aggcaggcct tgtcagatcc taactactgt tttgttccgt
     5761 tttttggctc tagcgaatgg agtcgcatgg atagcatgca cccatcagtg cttgcagaac
     5821 gctacaagcg ctcctacaga ccgtttttaa ttgggaaaag aggctctgct tccttatcac
     5881 aatattacgg catgcagcag atttcacagg aaataactgg aaaaaaggca gtctttgtcg
     5941 tgtccccaca atggtttacc ccccaaggca ttgatcctgg tgcggttcaa ttgtatctat
     6001 ctaatagtca ggtgattgat ttcctcttaa aagcaaaggc tagtcataag gaatcacaat
     6061 ttgccgctaa aagaatgctg gacattaatc cgggagttgc taaatcagag cttttaagga
     6121 aaattagtca aggcaaggcc ttgagtagat gggacattcg tctgctcaaa tggcagcagg
     6181 agctgtcctt aagagaggag tccttgttta gcttccttgg tcgttcaaca aactatgagg
     6241 ataggatttt gcctcgtgtt aaagggttgc ctaaaacctt ttcttatgag cgcttgagcg
     6301 agctagcagc cagacgggct aaggaaggaa cttcaaataa tcgctttggc atcaaaaatg
     6361 ctttttattc taagcgaatt gcaccgcaat ttcctcttta taagaatttt cagtgccgta
     6421 ataattacac tgtgtcacct gagtacaatg attttcagct ggtattgtca gaatttgcaa
     6481 aacgtaaaac agaggtgctt ttcgttatta cacctgttaa tcaagcgtgg gcaaattata
     6541 caggcttaaa ccagaggagg tatcaaaagg ctgtcagaaa aataaagcat cagttaacct
     6601 cgcagggctt tactcgcatt gctgattttt ccagaaatgg cggagacaag tattttatgg
     6661 aggataccat tcaccttggc tggaatggct ggctagcctt tgacaaggag gttgttcctt
     6721 tcttagagga tcaaacacca ccatctgaat accaactgga tccttacttc ctatcaaagg
     6781 actgggcaga tagaacagca ggattttagg gtcaatagac cattagaaaa tgaggattag
     6841 aattgttaat gagtatcatc gtcatattgc ttattttagc cattgctgtt ttagtgattg
     6901 agtatggtca aaagcggtcc ttttctagct ggctgcttga aaagatgttt gattatcgta
     6961 agtataagct ctctaaaaag gctgatgact atgaaggaat tgagacgcaa agacgtcgtc
     7021 gcattcccta ccacttggat aatccagagg cggtattggg gattcccacc acagaatata
     7081 cgattgatgg catgcaggtt tttgtgatca atgaccaaga ttctcaggat cagccagtga
     7141 tttactatct ttatggtagt gtctatttgc gtcgacctga gacatttcac tttaaaacca
     7201 ttaagcattt gatccattta accaatgcca agctggtgtt cccaaatttt gagaaggcgc
     7261 cttatgtcac ctataaggag atttacccaa agcttgctaa aacttatcag gagctttgtc
     7321 tagccaatgg cgctgccaag gttagcatta ttggtgactc ctcaggtggt ggcatggcct
     7381 tagccttggc gcaataccta agagataccc aaactgcacc acagccaaag caattaatcc
     7441 tgttatctcc ttggttagat gttagctttg ctaatcagga ttataagcat tttgaagcag
     7501 tagaggctta tttagatgct aggcggcttc gagacattgg tgaattgtgg gcaggcagtc
     7561 cagaagaaat gcggtctccg tatgtcagcc cattatatgg cgattatcat gacctgccaa
     7621 agattgtcac ttttgtcggg acaaaagaga ttttttaccc agatattatg accctgcatg
     7681 agcgcttgat ggagcaaggg cacttaaatc agctcgttat tgctgagcag atgattcatg
     7741 cttatgcgat cttcccgata cgagaggcaa ggcaggcgcg caagcagatt gccgagctga
     7801 ttttaaagaa ggagtgattg ttgctatagg agtcagttag ccttgcttgt ctgatgaggc
     7861 ttgggcttga gatttctaga gaagctttaa ggcctttact tgggctgtta atgctcatta
     7921 aagaggatta taggctttat actagggctt aggattgctg ttttgctatt caataatatt
     7981 agtttagact tgattgagga aaggctagtt ttagttatgg tcctcaatct ttttttgatg
     8041 gtaaacatgt caagacagtt tacttgctag ggtaataatc ctgtgctcat ttcatgagtg
     8101 gctattttta tcctaagctt ggtggtggaa aaatcagatt aaaaaatatg aaatttgcta
     8161 ttgacagctg taagcgattg cattataata aacttaactt aaacgtttaa gttaagttga
     8221 ataagctgat ttgatcatgc actgcctaaa tgcaatcaat aatctcaaag catttggtgt
     8281 agtctagtaa tcaatgaggc agtttattac ggttatacaa tatttattta gttcatccct
     8341 ttaggaggta aatagctatg gcgtgggatt ggaaaaaagc aggtgttgtt ggagtagtgt
     8401 cattggcttc gatcatggta ttaagtgctt gtagcggagg acatcaaaaa gaggctaagc
     8461 aaaaagacga caataccatt gtagtttcag ttgatgaggg ctatgcagac tacatcaaag
     8521 agattaagac agcctttgaa aaggacaata aggtcaaggt caaggtcaaa aaggaaggta
     8581 tgattgatac gctagataag ctatctactg atggaccgac aggtgcttca ccagatgtct
     8641 ttttagcacc atatgaccgg gttggtgggc ttggctctga agggcaaatt gctgaggtga
     8701 gcttaggcaa tgctgaccag tttgatgaca ctgttaaaaa gctagtcacc ataaatggaa
     8761 aggtttatgg ggcaccagat gttattgaga ccttagtgat gtattataac aaggatttgg
     8821 tatcagaggc tccgaaaacc tttactgaca ttgaagagct aaataaggat cctaagtttg
     8881 cctttgcttc tgaagacggt aagtctgtag gctttcttgc taagtggaca gacttctatt
     8941 atggctatgg cttgattgca ggctatgggg cttatgtatt tggagataag ggaactgatc
     9001 caaaggattt aggtattggt aatgctggtg ccattgaagg cttagactat gctaagaaat
     9061 ggtatagcgt atggcctcaa ggcatgcagg atactcaaaa ggctggagat tttattacag
     9121 agcaattcac ctctaaaaag gctggtgtga ttattgatgg accttgggct gctgcctcat
     9181 ttaaggaggc tggtgtaaac tttggagtgg cacaaattcc aagcttacct aatggcggta
     9241 gctatcaagc ctttggtggt ggtaaagcat gggtgatttc aaattattct aagaataaaa
     9301 agctggcaca gcaattcctt gattatgtga caaatgagaa aaaccaaaaa gccttttatg
     9361 gtaagacaca agagatccct gccaatctag ctgctcgcag ctatgctgca gaacaaggaa
     9421 atgaattgac aaaggcggtt attgggcaat tctcaaatgc tcagccaatg ccaaatattc
     9481 cagaaatggc agaagtttgg ggaccaggtg cgaacatgtt ctttgaggta gcagcaggca
     9541 agaagactcc tgccaaggct gctaaggaag cagctaaaac cattcaagag gctattgcac
     9601 aaaaatacac tgaataacat aaaaagggag gctgggataa aggtatccta gtctccatct
     9661 tgttacctat agtatcagag tgggcgatga ggagataata ataaaaagta gtagtgacta
     9721 gcttgtcttg tttcccatct tgtcctaata agagtatctg ataagactga tgaacctagg
     9781 gaggaaaaaa tgaacacagc cggaatactg catattccag attctagata ttgctttgcc
     9841 ttatcaacaa aggagcttgt gattcggttg agggttgcaa aggaggataa cgatatagcg
     9901 gtgacgctgg tttatggacc taagtatcat tatcatgagt atcaaaaaga actggcgatg
     9961 tatgctgctt ataccgatca tacccatacc tattatgaaa tcaccttaag tcttgatgat
    10021 gttagattgg cctatatttt taagcttgag caatctggtc acacctatta ctttagtgag
    10081 gatggcttga ccacaagcta tgatttttca aatggctttt acaacttttt tcaaatgcct
    10141 tatattaatg ctgtagacgt tcatcagact gtcccttggg tgcacaatgc tgttttttat
    10201 cagatctttg ttgatcgctt tcatcgtggt gactttgaaa aggacgatag ctatattaat
    10261 atggcttggc tggataggcc aactcctaat agctttgccg gaggggattt gaaggggatt
    10321 acagataagc tggaatacct tgaggatctt ggtattaatg tcatttactt gacaccgatt
    10381 ttcaaatcca tcagtaatca caaatatgat attagtgact actatgctat tgacccgatg
    10441 tttgggacat cgcttgatct ccagcaacta ataaacgagg cccaccaaag agggattaga
    10501 attattttag atgctgtttt caatcatgct agcagtgatt gcgagccatt tcaggacgtt
    10561 ttggcacatg gtagtgcttc ttcatttttt gattggttta tgattcaagg agatcatcct
    10621 tctgtagagc tagctaatta cgaaaccttc gctgattgtc actacatgcc taagtggaat
    10681 acctcgcatc aggctgttca ggattatttg attgagattg gtctttattg gatcacagag
    10741 tatcatattg atggctggcg attagatgtt tctgatgagg tatcgcatga tttttggaga
    10801 cgctttcgaa aggctgttaa ggcagtcaaa tcagatgcga tacttattgg agagaattgg
    10861 catgatgctt atccctacct tcaaggagac cagtatgatg gtattatgaa ttacgccttt
    10921 accaaggctt gtctcgatta ttttgcattt gatgcgatta gctcacagga aatggctgaa
    10981 agattgtcgc atattttaat gagaaatact tggcaggtca accagatgaa tctgaattta
    11041 ctggattccc atgatacgca tcgcttcttg actcaggtga atggctctaa ggacaaatta
    11101 ttggctggct tagccctttt agttaccttt atgggcatac catgtattta ctatggaaca
    11161 gagcttgcga tggagggagg ttatgatcct gactctagac gtagctttaa ttgggacagc
    11221 agcacttggg atatgagctt ttggaatcag gttaaggaca ttatcagcct gcgtcgtcat
    11281 gcggttatcc aatttggaag catttcgata acctcccatg atgactgcct ttgcgtaaag
    11341 cgtgaattaa acggtcaatc gataagattg ctggttaata atggcgttaa gccatatcct
    11401 attgagaaag gaggttctgt gcttgtttct aatggtgtag ataaagagac atttgagcta
    11461 ctccagaacg ggtttgttgt tagctattaa tatggcgttt tatcaaagga ggttaaggat
    11521 gaagcgtatt actttaacat gtcgtaaagc attaacagta gctatggcag cggttacctt
    11581 agcaatgtca actaacagtg tctttgctat tgaaaatact gcggtgtcta ataaggctga
    11641 tttttctact gacacgattt atcaaattgt caccgatcgt tttcatgatg gtaatgctgc
    11701 taataatgga aatacagatg tatttgataa aaatgatcct aaaaaatatc atgggggtga
    11761 ttgggcaggt atcattaaga aactagaaga tggctactta accaatttag gggtatcagc
    11821 tatctggatt tcatcaccag ttgaaaacat tgataccatt gacccttcaa atggcagtgc
    11881 agcctatcat ggctactggg caaaggattt tttcaaagca aacagtcact ttggaacaat
    11941 ggaggatttt aaaaagctca ttcaggtggc acatggcaaa aacattaaag tagttattga
    12001 ttttgctcct aatcatacct caacagcaga atataatggc ttaaccttcc ctgaggacgg
    12061 tgctttatat aaggacggcc agctggttgg taaattcagt catgatgatc aaaagatttt
    12121 caatcatgaa tcatggactg atttttcaac ttatgaaaat agcatttatc attccatgta
    12181 tggcttggca gacttgaaca atctgaatcc aacagttgac gattatctca aagaggctat
    12241 tgataaatgg ttagaaatgg gcattgatgg tattcgtgta gatgcggtca agcatatgtc
    12301 acaaggctgg caaaaaaatt ggttgagtca tatctatgag aagcataatg tattcgcctt
    12361 tggggaatgg tttgctgacg gttcttttaa tgatccattg atgactaaat ttgctgatac
    12421 tagcggcatg agcctgcttg attttaggtt tgctaattct gttaggcgcc tgtattctga
    12481 tttatcagcg aaaatgcaag atttttacaa tatgattgta gctacggaaa aagagtacaa
    12541 ggaagtttca gatcaagtga ctttcattga taaccatgat atgacccgct ttgctactct
    12601 agtcaatcat aatcagacag ctgttaatca agcctatgct ttactgctaa catcgcgtgg
    12661 tgttccgaat ctttattatg gttcagagca gtatgctaca ggtgctaacg accctgaaaa
    12721 tcgtggtgat atgccaacct ttgataagaa ttccactgct tatcaggtga ttagcaaact
    12781 agcaccactg cgtaagaaaa atcaagccct ggcttatggt acaacacagc agcgctggat
    12841 taatgatcag gtcttggtct ttgaaagaaa atttggaaat gacgttgctt tagtggctgt
    12901 taataaggat caaacaaatg gctacacaat tagtggcgct aaaacggctt taccagctgg
    12961 taagtatgct gatgaattag gtggcttact gggcggaaag gaattaacgg tatcagctga
    13021 tggtaatgtt gaggcatttg agttaggtgc gggtcaggtt gcagtttgga cctttaaagg
    13081 gcaacatgag acaccgcaga taggagacgt agacgcttcg tttggcgttg caggaaatac
    13141 tgtctctatt tcagggcaag gatttggtag tgctcaaggt cagcttcatt ttggtgatag
    13201 caaagcagat attgtgtcat gggacgatac cttgattcaa tttaagatac ctgctgtagc
    13261 tgctgggaac catgatatta aggtgaccac atctacagga caaagcagta gcccttacaa
    13321 agcctttgaa gtgttaacag ataagcaaat tccagtaaga ttggtggtca ataatttcaa
    13381 cactgtatta ggtgagcagc tttatatcgt tggtgatgtg gttgagcttg gggcaaatga
    13441 taatcataaa gctttagggc ctatttttaa tgcaacacag tcaattgcgc agtacccaaa
    13501 ttggttctat gatgtcaatc tgcctattaa caaaaccatt aactgtcatc ttgtaaagaa
    13561 ggatagttct ggtaaagtat tgtggactag tccagaaacc tataccatta aaactgatag
    13621 caaggctcaa accatttcat tgaaaaaata gttgcgttat ctgtgatgtt atttaatact
    13681 ctatgaagga ggagaaccat aaaagggtga tagagaggaa tgacaaatgc ttaagaatga
    13741 aaaaatgaag aatccacaaa aagccatgtg gctttcaata atccctggtc tggggcaact
    13801 ctacaatact caaaaggtaa aaggctttat tttgcttctt gtgtttttag gtgagctgct
    13861 agaggctttc tttgttggta ttccggctct tgctggcttg tacagccttg gtagtgtacc
    13921 aatggaggat cattccctat tcttattgat taagggagct atgcagctta tcctatttgc
    13981 cttgtttttg atctttcatt tggctgctat gcgagatgct agactagtgg caagggagat
    14041 caatgcaggc catagcattt cattaacctt aaaggagatg gtacaatcca tctatgaaaa
    14101 gggctttcct tatttgctga ttattccagc ctacttggcc atggcctttg ccattgtttt
    14161 tccggtgctt gttactttat taattgcatt tacaaactat gattttaggc atattcctcc
    14221 ctataaatta ttagattggg ttggcattaa gaattttaaa agcattttag agcttagcac
    14281 ctttaagtca gcctttggct ctgtgctgtc atggaccttg atttggacct tggcggcaac
    14341 gagtctccag attgtgatag gaatagcgac tgctattatt gccaaccagt cctttgtgaa
    14401 gtgcaggcgc atttttgggg tgattttctt gctgccttgg ggggtgcctg cttttatctc
    14461 gatcatgagc tttggtaatt tctttaatga ttctatcggt gctatgaatg ttcaggtctt
    14521 accattttta gaaaagtttg tgccatttgc agattttggg attatcccat ggaagacaga
    14581 tcctttttgg acaaaggttg cggtgattat ggttcagggc tggctgggct ttccttatat
    14641 ttatattttg gtgtctggta ttttacaatc aattcctgct gatttgtatg aggcagcaac
    14701 ggttgatggt gcaacagccc tgcagaagtt tcgccaaatt accttgccaa tgatctttgc
    14761 tgtcgcagcc ccgaccttaa tctcgcagta tacctttaat tttaataact tctccattat
    14821 ttatctcttt aataatggag gtcctggtac agttggcggt ggcgcagggt cgacagatat
    14881 tttgatttct tggatttaca agctgaccac acaaacgtca ccacagtttt ccattgcttc
    14941 agcggtgacc ttaatcattt ccttgattgt tatttctgta tcattgataa cctttaaaaa
    15001 attcaaagcc tttgacatgg aggatcgcta aatgggtagg aattatttgc cacagtcagt
    15061 gaagaagaag cgcttgttag ctcagctgtt gacttacagc tatttgctaa tcctgtcgat
    15121 catcatctta tttccaatct tggtgaccgt tagctcagcc tttaggccag gaaatacaac
    15181 tgcctttagc tttcatattg atgggccttg gaccttatca aactttgaga cactctttca
    15241 ggacacctat tacttaagat ggtactggaa cacgttagtt gtcgcctttt tcacgatgct
    15301 gatccaggtg acagtcatta cgctgacagg ctatgcttac agccgttatc acttttttgg
    15361 gcgtcaaaag agtttggtct ttttcttagt ggttcagatg gttccgacaa tggctgcctt
    15421 aacagcttat tttgtgatgg cttggttgtt taatgctctg aatcactatt ggttcctcat
    15481 tctgatttat gttggaggag gcattccgat gaatgcttgg ttgatgaagg ggtattttga
    15541 tactgtgcct tatgatttag atgagtcagc taagctagat ggctctggtc actttaggac
    15601 cttctaccaa attgtatttc ctctggttcg tcctatggtt gctgttcagg ccctatgggc
    15661 ctttatgggg ccatttggtg actttatgct tgctaagttt ctcttgcgtg aacaggagca
    15721 ttacaccgta gcggtaggtc ttcagtcatt catcactaac gacgctaggg atcctaaggt
    15781 cacattgttt gcagccgggg ccattttaat tgcagtgcca atttcagtgc tattcttctt
    15841 tttacagaag cattttgttt caggcttaac caatggtgga acaaagggtt aatttatctt
    15901 tcaaggagcc tttatcatga ctaatgatcg atttcctatt tcttacacaa ccattatttt
    15961 ttctcctaaa atgatatttg ctcgttgcag tgcctttttg tggtggcaga atgtgatttt
    16021 agtgatcttt ctaaatgctc tggtgttaat gccgatcacg ctgcattatg caagcttgaa
    16081 gagctatccc ttagagcaca tagttagtaa tggtttagac tccttgacag aaaaaaccta
    16141 tcatgccttg acacaaggca ctatttggca tgatcgctat gatggaaaaa cagtccttat
    16201 agaggatact gatgctgttg ttgctgtatt gccaacacca gaaatagtag aagagctaaa
    16261 gaaagatcaa agaagccagc tgatattaac agaaacctca tggattttaa gctttcctga
    16321 tggtcaaagg ctaactgcta aggttaaagg caacaaggaa aggctaacgc gcttaacctc
    16381 tctagaggct gtcaaggcct ttgttaatca gcaatggtac aatagcaatc gtgccgctgt
    16441 gcttgccttt ttgctgctag tggctagcag tgtggtctat ctaggagccg gtttagtgat
    16501 cggaattggc tcgttatcac tgttattaac aagatctgct agattatttt cactcaagag
    16561 ctactcagaa tgcttgggtt tgctagtgaa ttgctttgga cttcctacgc ttttagcagt
    16621 gcttataagt ttttgggtgc acaatcctat tgttatcatg aatagtcagg tctttggcac
    16681 actgctcatg ctggttctag tcttttacaa aactcagttt agagatgagg agcaagcact
    16741 agcttagccc ttgctgacat caaaaaatcc ctccc
//
LOCUS       DARYXS010000043        16035 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.044, whole genome shotgun sequence.
ACCESSION   DARYXS010000043 DARYXS010000000
VERSION     DARYXS010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16035
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.044"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            104..313
                     /locus_tag="TV193_001133"
     CDS             104..313
                     /locus_tag="TV193_001133"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513335.1"
                     /translation="MTQVRVYLWLSCDDGDNIESNSMTSRKPLAKEDIKKVIVACLSF
                     SEVGYRLKEKGLGIRVSFWLLKSVI"
     gene            458..934
                     /locus_tag="TV193_001134"
     CDS             458..934
                     /locus_tag="TV193_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1513336.1"
                     /translation="MTQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAIPGGAMELGESSAETCRREFYEETGITVEPLRLLNVYTNFEETYPNGDKVQTVVML
                     YEVIAKADKAITDYQNDETLRLGYFSREEIAELSSISDKHRLMLAEYFAGEFQMGH"
     gene            complement(1097..2299)
                     /locus_tag="TV193_001135"
     CDS             complement(1097..2299)
                     /locus_tag="TV193_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEL1513337.1"
                     /translation="MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITK
                     ELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYA
                     KHNQQIDPSISSYYKADYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
                     NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYERQAHNHNFIFFHVGRGMHCS
                     YMYKGVIYSRHNAVVGEIGHTIVNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYA
                     PNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQI
                     YLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELY
                     LNYKNKYD"
     gene            2479..3378
                     /locus_tag="TV193_001136"
     CDS             2479..3378
                     /locus_tag="TV193_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEL1513338.1"
                     /translation="MKTRLLSASSSEMLQLTSLELKQAIKASEGRTIVSENVAPRPSW
                     TGDDLTNAEVAAAFSADLILLNCVDVFDVQISGLPATDQPILELRRLVGRPIGVNLEP
                     IDLDVDMTEKRLELVEGRQATAKTFQEIEALGFDFVCLTGNPGTGVSNNQIERAIQQA
                     KHYFSGLIIAGKMHAAGSNEAVIDLETVRRFIEAGADVILVPAVGTVPGFTEGDLRAI
                     VEEVHAHDALVMSAIGTSQEGSDTTIVRDIAIRNKICGVDIHHIGDAGYSGIAPVENI
                     FALSDAIRGKRHTIVRMSRSIRR"
     gene            3402..3719
                     /locus_tag="TV193_001137"
     CDS             3402..3719
                     /locus_tag="TV193_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1513339.1"
                     /translation="MSKKQIMLACAAGMSTSLLVTKMEKAADNRGLEADIFALPLTEA
                     EDYALSHPVDVVLLGPQVAYQLSAFQESLAEKDIPVAVVPMVDYGMMNGDKVIALAES
                     LMK"
     gene            3729..4061
                     /locus_tag="TV193_001138"
     CDS             3729..4061
                     /locus_tag="TV193_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1513340.1"
                     /translation="MEDKQLETIMGLIMHGGSAKSLAMEAIAFAKKGELNQAQESLKQ
                     ADKALVQAHHAQTDMLTQEARGNATPVSLLLVHGQDHLMTSITFVDLARELVSIYERL
                     TSQGGNND"
     gene            4054..5370
                     /locus_tag="TV193_001139"
     CDS             4054..5370
                     /locus_tag="TV193_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1513341.1"
                     /translation="MTKFEDFIQQKLVPVAGRLGSNRFLIAIRDGITYAMPLILIGSF
                     LMVIASLPIPGWEAWLGEIGVSTYLWKGVDSSFNLIALVAAFGISYSLAKQYKADGIS
                     AGIINISAFLTVTPFTVSFVNESGKALGEVAGIAPSYLSSGGLFVAIVLGLVNGYAYQ
                     WFMKKDIRIKMPEGVPPAVSKSFSAIIPGAVIIVFWLAVYAFLDHFSLPNVHDIVKSV
                     LGVPFGLLGSTLFGNFIVVLLNGFLWFCGVHGGNVLNNPIMKPIWLSNLTENMAAHKA
                     GQELPHVFTSVFMDNFVFIGGAGATIGLVLALAWLARRRKASQQAKVLSPLTLIPGFF
                     NINEPTMFGLPVVLNLLTVIPFVLAPVMNLFVAYFAFASGIVPGTYADPGWTMPPVIS
                     GFLATGSWQASVLQLVLIILDILLYLPFIINVERRWQASEQTKNEG"
     gene            5435..6782
                     /locus_tag="TV193_001140"
                     /pseudo
     CDS             5435..6782
                     /locus_tag="TV193_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            6955..11595
                     /locus_tag="TV193_001141"
     CDS             6955..11595
                     /locus_tag="TV193_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEL1513342.1"
                     /translation="MLFNPIGKEQIRKYAIKKLSVGVASVCVGIGLAAGLPVAVYADD
                     VSEVSLQQPTKAAVTEISHEQEPQATDTDSEALVVSEETTVDEAVVANAVTSNAADQT
                     ADEEKSNAPIELNKVANGGFDNDYVSNKNQWQYREGGHSVLTTENGNSYAEVTSGTLD
                     EHILQKVSTTVGKTYTLEADVKVEADTPHNGLYLTAKESNHNLQGPVIKEVSLTDTDG
                     TWSHIKLSFTATTSETFVGLVKWLEASSPEALAASASIDNVSVVEENDYELIWQDEFS
                     GDRLNQENWGYELGSIRGNEQQHYTDSTENVYLDNGNLVLNVTERYGEDRYANPRGGT
                     SARQVIYDSGSVRTVGKQEFLYGRIEARAKLPKGKGAFPAFWTLGADFTLDGDIASTQ
                     GYGWPSTGELDIMELIGAPNGEHEGELAEGDQSNKTVYGTPHFYYIKGDADKDGSYSP
                     TALGGNLTLSDDFYDDYHIFGINWYPDKIEWYVDGIVYNTMYLTGDDRLEAAAAAFNK
                     PQYLQFNLATGGNWSKNAGYYLASDETAFVIDYVRYYQDAEQKAASEAYYASQPVLKG
                     VKDLTMLEGTSPDLAQAVTTDQEGYVVDFSVENEYLFTNKGGNTNAALQAAGRDDLSA
                     LSELAPGIYNIYYSAVPYNADLGSTVTPTAKIAREVAILTVLPKEGLIGKKGEPLSTV
                     ALPANWQWVTPEEILGSAEHYQIKYTTEGGRAVYTSIEASYISDQPISDQASILVDLG
                     NAILDATAEKAAVTDDEALGKLDDVMNLTQGTVTIRYRLDTADTTVRSSSPLALLSIS
                     NQASANEYASFFIEPKNNKIGLEFKGAEVPIVKVGSGFNLLTNSDWQTISYVFTGSRL
                     KIYLNGDLYGEADFAGFMKQLPWKASADTLTIGGLKRTYDGESVLHWGLKGLVDQVLI
                     DTDVYDLTDIAKAHQPTLRPVTGEKTNVWDKYDEGVFEYRIPSVVKTPSGTLIAAADA
                     RKKHYNDWGDVATVVRISHDDGKTWSNNITVLDMPTQPYFTTQYSLADWNTNMTQSAF
                     SIDSTLLTDASGKLYLLVDVFPESQGAVASKAGSGYELINGQYYLNLYDFDNNKYTVR
                     EGGIVYDQSGHQTDMYVDEGNFETAFSTRGNLYQTEAGEDILLGNIYLRSGRTKQGIT
                     REGSQTAPLFTYMTSFLWLLTSEDEGQTWSTPLDITPQIKEDWMGFLGTGAAAGIEID
                     AVNAEGEQVKRLVFPIYYTNQQNATSASLGRQSSANIFSDDGGQTWQRGESPNDGRIY
                     GHNQQTTSKDFDTSVTELTENQIIQLNNGHLLQFMRNTGKTIVIARSTDYGMTWDDNP
                     TITDLPEPYVNLSAIHMMVDGKEYVVLSNPLGEPSGEQLTIRNQRMKGILRVGEVLED
                     DSIHWVASTIFEPKRFAYSSLVQLDDERVGLLYEYSGQITYSTFNIKQMISDQFREDK
                     AEIEEVTITSAAPKQNGKVSITIQMTFNQPMFILGDRQLAVTVNGVDKLASYVSGDGT
                     DTAIFELSLESMPEGPITVLPQFDHTIVETKYGIRLTDDKAYTVSYPAAVTA"
     gene            11756..13555
                     /locus_tag="TV193_001142"
     CDS             11756..13555
                     /locus_tag="TV193_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1513343.1"
                     /translation="MERFQISDQFYLDGRSLQILSGAIHYFRIHPDDWYHSLYNLKAL
                     GFNTVETYVPWNLHEAREESYDFSGQLDVEAFLTLAQQLGLYAIVRPSPYICAEWEFG
                     GLPAWLLTKNCHIRSSDPVYLAYVRRYYEELLPRLARHEWQQGGNILMFQLENEYGSY
                     GEDKAYLTAVKGFMEEHLSAPLFTADGPWRATLRAGSLIEDDVFVTGNFGSRAQENFA
                     DMQAFFSEHGKHWPLMCMEFWDGWFNRWHEPIIKRDPEERADAVMEVLAQGSINLYMF
                     HGGTNFGFMNGCSARKQLDLPQVTSYDYDAILDEAGNPTAKFYAIQKRLTAELSEIEV
                     TPPLIKPLMSLPLIGLKDKVSLFSTLEHISSCQTACYPSNIEALGQSTGYILYRTHLL
                     KDKREDERLRLIDSRDRAQVFLDGQKVATQYQETIGDDIIINQQHALSQVDVLIENMG
                     RVNYGHKLTAPSQSKGLGRGMMADLHFVTNWEMYCLPLDDLSQLCFDGDFYEGQPGFY
                     HYQFECHEPEASYIDMTGFGKGCVFINNHPIGRFWEVGPLLTLYIPKGYFNKGLNDIV
                     IFETEGVYQDSIRLVDRPISIDYPQADDRTDQT"
     gene            13970..14791
                     /gene="mutM"
                     /locus_tag="TV193_001143"
     CDS             13970..14791
                     /gene="mutM"
                     /locus_tag="TV193_001143"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEL1513344.1"
                     /translation="MPELPEVETVRRGLERLVVGKQIAAVTVRVPKMVKTDLEHFVMT
                     IPGQQVQGVDRRGKYLLFDFGQLVMISHLRMEGKYLLFPDTVPEHKHFHVFLTMTDGS
                     TLVYQDVRKFGTFDLLPKAELAAFFQKRQLGPEPTKQTFQLKTFEAALLASKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAARVHPERRSASLKKAEIKRIHDETIRILQLGIEKGGS
                     TVRTYQNTLGMNGSMQHYLMVYGQTGKPCQRCGTSIVKLKVGGRGTHVCPRCQKQ"
     gene            14788..15381
                     /locus_tag="TV193_001144"
     CDS             14788..15381
                     /locus_tag="TV193_001144"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEL1513345.1"
                     /translation="MTKVIGITGGIASGKSTAVALIRQAGYQVIDADQVVHELQKKGG
                     KLYQVLLETFGQDILLPSGQLDRPKLAELLFAHSENMAKSSQQQNAIIREALAKQKEE
                     LSQTEAIFFMDLPLLVELGYQDWFDAIWLLYVDEETQLKRLMKRNQLTELAARQRIAS
                     QLPMSQKRAYADLVIDNTGDFQALETQISKALHDLEA"
     gene            complement(15544..15900)
                     /locus_tag="TV193_001145"
                     /pseudo
     CDS             complement(15544..15900)
                     /locus_tag="TV193_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677601.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT         4288 a         2939 c         4003 g         4805 t
ORIGIN      
        1 ttataaaggg tattttattt aaagattttg aaggaaaaaa acacctatag gtacaatcaa
       61 tcaaaaaaac agtaggtacc tactactgat tgaggagaag gcaatgacac aagtacgtgt
      121 ttatttgtgg ttatcatgtg atgatgggga taatattgaa agtaattcaa tgaccagtcg
      181 caaaccattg gccaaagaag acattaaaaa agttatcgta gcttgtctga gtttttctga
      241 ggttggttat agattgaaag aaaagggact tggcattcga gtctctttct ggcttttaaa
      301 aagtgtgata taatcaggtt gaaaaattag ggctatatgc tttgccagcc tatcaaggac
      361 aagagacaaa gcctgcattg cttattggtt ggcaaaaaag cagcaattgc gccagctgac
      421 tggctttaat cttatgatgg caatgaaggg agttacgatg acacaggact atatttccta
      481 tattcgctca aaggtggggc atgataacat tattctgact tttgctggtg gtattttggc
      541 caatgccgaa ggtaaggtgc ttttgcagct acgtgcagat aagaaaacct gggcaattcc
      601 gggaggtgcc atggagctgg gtgagtcttc tgctgaaacc tgcaggcgtg aattttatga
      661 ggagacgggg attacagtag agcctttacg gttgttgaat gtttatacca attttgaaga
      721 gacctatcca aatggtgata aggttcagac cgttgtgatg ctttatgagg ttatagccaa
      781 ggcagataag gctatcactg attatcaaaa tgatgaaacc ttaaggctcg gttatttttc
      841 tagagaagag attgcagagc tgtcttcaat ctcagacaag catagactga tgctggcaga
      901 gtattttgct ggtgagtttc aaatggggca ttaggataga acagagagaa ccaagtgcct
      961 ctcttttttt atggttatca tttgtctcgc acctgcggag cgagatggac tgaaagtcgc
     1021 ataatgcaaa agcccacttg agaaatagct tctcaaatgg gctttaaagc tttagctgat
     1081 attggtgtgg gggttatcaa tcatatttgt ttttataatt gaggtaaagc tcatctatac
     1141 ataagcctgt agctcccaca gcggcattat agacagaaaa aggcatgaca atgatttctg
     1201 gctttttttg attgctaaga agcttaatgt cattttgcag ggcttgcaga attttggagg
     1261 atataagagg atggctgata aatctgccat ggagatagat ttgctcggta tcaatcagta
     1321 aggagaggtt agacagggat aaaacaaggt aatcaatagc tgtgtgaatg agcgtggtca
     1381 ccccgacatc accaagctca taggcaatca agagatggtc tagcttgagc tcacaggcct
     1441 tatcgacaag gcttcttaga tgagaattgg gggcatactg atgtagcagt tttgcttttt
     1501 tgagcaacca ggcattgctg gcataggtct gtaaacagcc ttttttgcca cattcacaaa
     1561 gctctccagt ggggttgaca atggtatgtc cgatttcccc aacaacagca ttgtgacggc
     1621 tataaatgac ccccttatac atataggagc agtgcatgcc tcgtccgaca tgaaagaaaa
     1681 taaaattgtg attatgtgcc tgacgctcgt ataagcgctt ggcaataatc atacagtgag
     1741 cattgttgct aaagaccact ggaataggga aggacttcgc aattgcggtt aaatcgacct
     1801 gctgccagat gggattgttg gtgttaatat gcgttgagct ggaggtggaa tgatcgtaat
     1861 gcccaggcag tgctattcct atggcttgta catcatagtg cttgtgctgc ttgaggaagg
     1921 cttgaatcag ctcagagata tagtctgctt tgtagtagga ggaaatgctt gggtcgatct
     1981 gttggttgtg cttggcatag atggtgccca ggttatctgt aatgaccaaa tagaaatgct
     2041 tttcggacaa ttcgacacca gcaaaataaa aggcgttagc cgaagcatca agtaatattt
     2101 ttttgcggcc aacggagtgg tccgtcagct ctccgatttc gtgtatccac ccctgtgcta
     2161 gcagctcttt agtgatagcc cctactgtag caggtgtgat gtgcgttagc tttgaaatat
     2221 caatgcgtga aataggccgt tgggcataaa tggtatctaa aatttttgcg taaagctctt
     2281 gttgtttatc cgtcttcata gtaacctcta ttatcgtacc tctatcatac caaaaaagaa
     2341 ttaaaaatcc tgcctgaaaa cgttgacaaa tattggtaaa tagaatacac tttatttgtt
     2401 tataaaaagt aaacaaataa gagttaaatc ttatttatct tttgttaatg tttttaaaat
     2461 aaaaataaag gagaagcgat gaaaacacga ttattgagtg ctagtagctc agaaatgcta
     2521 cagttaacat cgttagagct aaagcaagcc attaaggcaa gcgagggacg taccattgtc
     2581 tcagaaaatg tagcgccaag accctcttgg actggagatg accttacgaa cgctgaggtt
     2641 gccgcagcct ttagtgctga tttgattttg ctgaattgtg tagatgtctt tgatgttcaa
     2701 atatctggtc tacctgctac tgatcagcct attttagagc tgcgtcgtct ggtggggcgt
     2761 ccaattggtg ttaatttaga accaattgat ttggacgttg acatgactga aaagcgcttg
     2821 gagctagtag aagggcgaca ggcgacagct aagacctttc aagagattga agccttgggc
     2881 tttgactttg tttgcttgac aggaaatcca ggtactggtg ttagcaataa tcagattgaa
     2941 agagctattc aacaggccaa gcactatttt tcaggcttga ttattgctgg aaagatgcat
     3001 gctgctggct ctaatgaagc ggtgattgac ttagaaactg ttcggcggtt tatcgaggct
     3061 ggggctgatg tgattttagt tcctgctgtt gggacagttc ctggctttac agagggtgac
     3121 cttagagcta ttgttgagga ggtgcatgct cacgatgctc tagttatgtc agctattgga
     3181 acgagtcagg aagggtcaga tactacgatc gttcgagaca ttgctattcg caataaaatc
     3241 tgtggtgtcg atattcatca tatcggagat gctggctata gcgggattgc gccagtggaa
     3301 aatatctttg ctcttagtga cgctatccga ggaaaaagac ataccattgt gagaatgtcg
     3361 cgctctattc gacgttagga tttgggataa aggagaagat catgagtaaa aaacaaatta
     3421 tgttggcctg tgcagcgggt atgagtacca gtctattagt gacaaagatg gaaaaggctg
     3481 ctgacaatcg ggggcttgag gcagatattt ttgcattgcc attgactgag gcagaggatt
     3541 acgctctaag ccatcctgtt gatgtggtgt tattagggcc acaggttgct tatcaattgt
     3601 cagcatttca agaaagcttg gcagaaaagg acattccagt ggcggttgtg ccaatggttg
     3661 attacggtat gatgaatggt gataaggtta ttgccttagc tgaaagtttg atgaaatagg
     3721 tggtggtcat ggaagataag cagctagaga cgattatggg cctgatcatg catggtggta
     3781 gtgccaagtc gcttgcgatg gaggcgattg cttttgctaa aaagggagag ctcaatcaag
     3841 ctcaggaaag tctaaagcag gccgataagg cattggtgca ggcccatcat gcacaaacag
     3901 atatgctaac tcaagaggca cggggaaatg ctacaccagt aagcctacta ttagttcatg
     3961 gtcaggatca tttgatgact agtattacct ttgttgattt ggcaagggag ctagtatcta
     4021 tttatgaaag gttaacgtca caaggaggta acaatgacta aatttgaaga ttttatccag
     4081 caaaagcttg ttccagttgc tggtcgccta ggaagcaatc gctttcttat tgctattcgt
     4141 gatgggatca cctacgctat gcccttgatt ttgattgggt cctttttaat ggtgattgct
     4201 agcctgccga ttcctggttg ggaagcttgg cttggtgaga ttggtgtctc tacctatctg
     4261 tggaagggag tagattcgag ctttaatctg attgccttgg ttgcggcctt tgggatttct
     4321 tatagcttgg ctaagcagta taaggcagac gggatttctg ctgggattat taatatctct
     4381 gcctttttaa cagtgacccc atttactgtt tcatttgtca atgaatctgg taaagccttg
     4441 ggtgaggtag cgggtattgc gccttcttac ctttcatcag gcggcttgtt tgttgccatt
     4501 gttttgggat tggtaaatgg ctatgcttat caatggttta tgaaaaagga tattcggatt
     4561 aagatgcctg agggtgtgcc gcctgcagta tcaaaaagct ttagcgccat tattcctgga
     4621 gcggtgatta ttgtgttttg gcttgctgtt tatgctttct tggatcattt tagcctgcca
     4681 aatgtccatg acattgttaa gtccgtacta ggagttccat ttggcttgct gggaagtacc
     4741 ttatttggta attttatcgt tgttcttctt aatggctttt tatggttctg tggtgtgcat
     4801 ggtggaaatg tcctaaacaa tcctattatg aagccgatct ggttatctaa cttgactgaa
     4861 aatatggcag ctcataaggc tggtcaggaa ttgccgcatg tctttacgtc tgtctttatg
     4921 gataactttg tttttatcgg cggagctggt gcaaccattg gcttggtgtt ggctttagcc
     4981 tggttagcac gtcgtcgcaa ggctagtcag caggcaaagg tcttgtcacc attgaccttg
     5041 attccagggt ttttcaacat taacgagccg accatgtttg gcttaccggt tgttttaaat
     5101 ctattgacag ttattccttt tgtactagca cctgttatga atttgtttgt cgcttatttt
     5161 gcctttgctt ctggcattgt acctggcacc tatgctgatc cggggtggac catgccgcct
     5221 gttatttcag gatttttggc aacgggcagc tggcaagcct cagtcctaca gcttgtttta
     5281 attattctag atattcttct ttacttgccg tttattatta atgtggaaag aagatggcag
     5341 gcgagcgagc aaactaaaaa tgaaggctaa gctgttagag agagccttta ctgctctatc
     5401 ttagctgttt tatgattgtt ttaaggagct atgaatgaat aactatatga actttctttc
     5461 gcaaaagctg ctgccaattg ctacgaagat tggtaatcaa cgatttttag tggccttgcg
     5521 agattctttt attgcaacga tgccggttgt gatgacaggc tctattgccc tgttgatcaa
     5581 tgccttttta gtggatattc cagaccaatt tggcttgcaa ggcattacag aggccttcca
     5641 atggtgggta accatcaaca accttgtctt taagggaagc atttcgattg tgtccttgct
     5701 atttgtgtat tgcttagggg ttaatgtcgc taaactttat aagacagata cgctctcatc
     5761 aggtttggtt tctttagctg cctttgtgat tgcgattggg gattctgtta cctctagcat
     5821 tgacgcgtca ggtctcaagg gtgttgatct tgtgacggct tttaaggaca gtggtgttac
     5881 tgtcagcggc agctcactta atgtgaccat ctcaggccta ttgcctggtg cgcaaattaa
     5941 ctccaatggt tattttacag caattatgat tggcttttta gcctctatta ttttttgtaa
     6001 attaatgtta aaaaattgga caattaaatt accagatagt gtgccacctg ctgtagccaa
     6061 gcccttctta tctatcatac caggcttttg cgccttgtat agcgtagcta ttttaacatt
     6121 tgtctttgaa aagctaacgg gttctttgat gattgattgg atctataagg tcttgcaaat
     6181 cccacttttg ggcttatcac aaagctttat tgctgttgtt ttggtagctg ttttgaccca
     6241 atttttctgg ttctttggga ttcatggcgg caatgttatg gcgccaaata tggagggagt
     6301 atttggtgtt gccctcttgg ctaatttgga ggcttatcaa aagcatgagg cgattcctta
     6361 tctttggacg agtgttcttt gtatggtatg caaccttagg gctcttgatt gctattttct
     6421 ggaagtctaa aaatgaacac tatcgtgagg tggctaagct aggtgttgct cctgtattgt
     6481 ttaatatagg agagccagtg atgtatggtt taccaactgt tttaaatcct ttgttgttta
     6541 ttccgtttat tgtttgtcct gctgttatgt caagtgttgc ttatatcgca actagtctgg
     6601 gcttggttgc acccgttacg caaaatgtga cctgggtaat gccgcctgtc ttgtatggct
     6661 tcttttcaac tggttttgat tggcgtgcta ttgtgctatc gcttgtcaat ttggccttgg
     6721 caaccctgat ttaccttcca tttgttaaga tggctgataa tgagcttgaa aaggcaggtt
     6781 agtcactttg tgagaggata tatcggtttc atctggtata tcttctttta agcgctgaat
     6841 tgaaagcgtt tttataacaa ggtcgttagc ctgaccagca ctggattagg ctaaatgggc
     6901 ctttgaaaag ctattgtgtt taaaaatgat gtatatataa gtgaggaaat aaacatgtta
     6961 tttaatccta tcggaaaaga gcaaattaga aaatatgcca tcaaaaagct tagtgtcggt
     7021 gttgcttcag tgtgtgtggg tattggtctt gctgctggtc tgccagtggc tgtttatgct
     7081 gatgacgttt cagaggtaag cctgcagcag cctacgaaag cagcagtaac agagataagc
     7141 catgagcagg agcctcaagc tacagataca gatagcgagg ccttagtagt ctcagaggag
     7201 acgacagtag atgaggcagt agtagctaat gctgtgacca gcaatgctgc tgatcagaca
     7261 gcagacgaag agaagtctaa cgctccgatt gagctcaata aggtggctaa tggtggtttt
     7321 gacaatgatt atgtgtccaa taagaatcag tggcaatata gagagggagg tcattcagtc
     7381 ctcacaacag agaatggtaa tagctatgct gaggtaacaa gcggcacttt agatgagcat
     7441 atccttcaaa aggtgtctac aacggttggg aaaacctata cgctagaggc tgatgtgaag
     7501 gttgaagctg acacacctca taatggctta taccttaccg ctaaagagtc caatcacaat
     7561 cttcagggcc ctgttatcaa agaggtcagc ctcacagata cagacggtac ttggtcacat
     7621 atcaagctct cctttacagc aacgacttca gaaacctttg ttggcttagt caaatggttg
     7681 gaagcctctt ctccggaagc cttggctgcc tctgctagta ttgataacgt gagtgtcgta
     7741 gaggaaaatg attatgaatt gatttggcag gatgagtttt caggagatcg gttaaaccaa
     7801 gagaactggg gatatgaatt gggaagtatt cgcgggaatg agcagcagca ctacacagac
     7861 agcacagaga atgtctatct tgataatggc aatcttgttt taaacgtcac agagcgttat
     7921 ggggaggacc gttatgccaa tcctagagga ggaacaagcg cacgtcaggt catttatgat
     7981 tcaggaagcg tacgaacggt tggcaagcaa gaatttttat atggtcgtat cgaagctagg
     8041 gccaagcttc ccaagggtaa gggagccttt ccagcctttt ggacattggg ggctgatttt
     8101 accttagatg gtgatattgc gtcaactcaa ggctatggct ggccaagcac aggtgagctt
     8161 gacattatgg agctaatcgg tgctcctaac ggagagcatg agggtgagct tgccgaaggt
     8221 gatcaaagca acaaaacagt ttacgggacc cctcattttt actatatcaa gggtgatgca
     8281 gacaaagatg gaagctatag cccaacagca ttgggtggca atctgacatt aagtgatgac
     8341 ttttatgatg actaccatat ctttggtatt aattggtatc cggataagat tgaatggtat
     8401 gttgatggga ttgtttataa taccatgtat ttaaccggtg atgatcgctt agaggctgcc
     8461 gcagctgcct ttaataagcc tcaatacctt cagtttaacc ttgctactgg aggcaattgg
     8521 agtaaaaatg caggctacta tctagcttca gatgagacgg cctttgtgat tgattatgtg
     8581 cgttattacc aagatgctga gcaaaaagca gcctcagaag cttattatgc ctcacagcca
     8641 gttctcaagg gggtcaagga tttgaccatg ctagagggaa ccagtcctga tttagctcaa
     8701 gctgtaacca ctgatcagga aggctatgtg gttgattttt cagttgaaaa tgaatacttg
     8761 tttactaaca agggtggaaa taccaatgct gctttacagg ctgctggtcg agatgatttg
     8821 tcagccttgt ctgagctagc tcctggtatt tataacattt actatagtgc tgttccttac
     8881 aatgctgatt taggctcaac agtaacacca actgctaaga ttgcaagaga agtagctatt
     8941 ttaactgtat tacctaaaga aggtctgatt ggtaagaagg gagaaccctt atctacagta
     9001 gccctgccag ccaattggca atgggttacg ccagaggaga tcttgggaag tgcagagcat
     9061 tatcagatca aatacaccac agaaggcgga cgagctgttt atacaagcat agaagcaagc
     9121 tatatctcag atcagccaat ctcagatcaa gcatccattt tagttgattt aggcaatgct
     9181 attttggacg caacagcaga aaaagcagcc gtaacagatg acgaggctct tggtaagcta
     9241 gacgatgtga tgaacctaac ccaaggaact gtaacaatca gataccgtct agatactgct
     9301 gatacaacag tgagaagctc atcgcccttg gccttgttat cgatctcaaa tcaagcatca
     9361 gctaatgaat acgcctcttt ctttatcgag cctaaaaaca ataaaatagg tcttgaattt
     9421 aaaggagctg aggttccgat tgtaaaagtt ggctcaggct ttaatttatt aacgaactcg
     9481 gactggcaga cgatcagcta tgtctttaca gggtctaggc taaagattta cttgaatggt
     9541 gacttatatg gggaagctga ctttgctggg tttatgaagc aattaccttg gaaggcttct
     9601 gctgatacgc taacaattgg aggcttgaaa cgcacctatg atggtgagtc ggtccttcac
     9661 tgggggttaa agggactggt tgatcaggtg ctgattgata cagatgtgta tgatctgaca
     9721 gatattgcca aggctcatca gccaaccctt cgaccagtta ctggtgaaaa gacgaatgtt
     9781 tgggacaaat atgatgaagg ggtctttgaa tatcggattc cctctgttgt caaaacgcca
     9841 tcaggaacct tgatagccgc agcagatgca agaaagaagc actacaatga ctggggagat
     9901 gttgcaactg ttgtcaggat aagccatgat gatggcaaaa cctggagtaa taacattacg
     9961 gtcttagata tgccaactca gccttatttt acaacacaat atagcttggc tgattggaat
    10021 accaacatga ctcaatctgc tttttcaata gactccacct tgctaacaga cgcttctggc
    10081 aagctttatt tgctggtaga tgtctttcct gagtcacagg gtgctgttgc ttctaaagca
    10141 ggctcaggat atgaattgat taacggtcag tattatttaa atctttatga ttttgacaat
    10201 aataaataca ctgtgcgtga aggtggtatc gtctatgacc agagtggcca tcagacagat
    10261 atgtatgttg atgagggcaa ttttgagaca gcctttagca cacgcggcaa cctctatcaa
    10321 acagaggcag gagaggatat tctactaggg aatatttatc tgagaagtgg tcgcactaag
    10381 caaggcatca ctagagaagg ctcacaaaca gctcctctat ttacttacat gaccagcttt
    10441 ttatggctgc taaccagtga agacgaaggg caaacctggt ccacacctct tgatattacc
    10501 ccacaaataa aagaagactg gatgggattt ttaggtacgg gtgccgcagc tggcattgaa
    10561 atagacgcag tcaatgcaga gggtgagcag gtgaaacggt tagttttccc gatttactat
    10621 accaatcaac aaaatgcgac atcagctagt ctaggtcgtc aaagcagtgc taatattttt
    10681 agtgatgatg gcggtcaaac atggcaacga ggtgaatcac caaatgatgg cagaatttat
    10741 ggtcataacc aacaaacaac ctctaaggat tttgatacat cagtcacaga attgacagaa
    10801 aatcaaatca ttcagctaaa caatggtcac ttattacagt ttatgcgcaa taccggaaag
    10861 acaatcgtta ttgccagaag cacagactat ggtatgactt gggacgataa tcctacaatc
    10921 acagacctcc cagagcctta tgtcaatttg tcagctattc atatgatggt tgatggcaaa
    10981 gaatatgttg ttttatccaa tcctttagga gagccctcag gtgagcaact gacgattaga
    11041 aatcagcgca tgaaagggat tctgcgtgtc ggtgaggtct tagaggacga tagcattcat
    11101 tgggtcgctt caaccatttt tgagccaaag cgttttgctt actctagctt ggttcaacta
    11161 gacgacgaga gggttggttt gttatacgaa tatagtggtc agatcaccta ttcaaccttt
    11221 aatatcaagc agatgatctc agaccagttt cgtgaggata aggctgaaat tgaagaagta
    11281 acaataacgt cagcagctcc aaagcaaaat ggcaaagtaa gcataaccat tcagatgacc
    11341 tttaatcaac cgatgtttat tcttggtgat cgtcagttag cagttactgt aaatggcgta
    11401 gataagcttg ccagctatgt ttcaggagat ggcacagaca cagcgatatt tgaattgtct
    11461 ctggagagta tgcctgaagg accgataact gttttaccgc agtttgacca tactattgtt
    11521 gaaaccaaat atgggattag attgacagat gacaaggcat acactgtctc ttatcctgct
    11581 gctgtgacag catagcatga ggagtcagac tgtagatagt gtttacaatt gttaccataa
    11641 gataagttag cctgtctgct gaatggcctg ttcgctgttg ctagaatagg ccattccaag
    11701 ccgctcagca atgaggccta gtaggctaat agcaataata agtgaggaat taagcttgga
    11761 acgttttcag atttcagatc agttttattt agatggtaga tcgctgcaaa tcctgtcagg
    11821 ggctatccat tattttagaa ttcacccaga tgattggtat cattcgcttt ataatttaaa
    11881 ggcactggga tttaatacgg ttgagaccta tgtcccttgg aatttacatg aggctaggga
    11941 ggaaagctat gatttctctg gccaattaga tgtggaagcc tttttgacgc tggcgcagca
    12001 attggggctc tatgctattg tcagacctag tccttatatt tgtgcagaat gggaatttgg
    12061 tggcctacct gcttggctgc tgacaaagaa ttgtcatatc aggtcgtctg atcctgtcta
    12121 tttagcctat gtgaggcgct attatgagga gctgctgccg agactagcaa ggcatgaatg
    12181 gcagcagggc ggcaatattt tgatgtttca gcttgaaaat gaatatggct cctatggaga
    12241 ggataaggcc tatttaacag ctgttaaggg ctttatggag gagcacctca gtgcgccctt
    12301 gtttacagca gatggtcctt ggcgagccac tcttagagct ggtagtctga ttgaagatga
    12361 tgtctttgtg actggcaact ttggctcaag ggcacaggag aattttgctg acatgcaggc
    12421 cttcttttct gagcatggca agcattggcc tttaatgtgt atggaatttt gggacggctg
    12481 gttcaatcgt tggcatgagc ccatcatcaa acgcgaccct gaagagcgag ctgacgcagt
    12541 gatggaggtt ttggcgcagg gcagtattaa cctgtatatg tttcatgggg gaacaaactt
    12601 tgggtttatg aatggctgct ctgccagaaa gcaattggac cttccgcagg tgacctccta
    12661 tgattatgac gctatcctag atgaggctgg caatccgaca gctaagtttt acgcgattca
    12721 aaagcgtctg accgcggagc tttcagagat agaggttact cctcccttga ttaagccctt
    12781 gatgtcactg cctctgattg gtctgaagga caaggttagt ctgtttagca cgctggagca
    12841 catcagcagc tgtcagactg cttgctatcc tagtaacata gaggctttag ggcaatcaac
    12901 gggctatatc ctgtatcgga cacatctttt gaaggataag cgtgaggacg agcgtttacg
    12961 cttgattgat agtagagata gagcacaggt ctttttagat ggtcaaaagg ttgcaacaca
    13021 gtatcaggag acgattggtg atgatatcat cattaaccag cagcatgcct tgagtcaggt
    13081 cgatgtttta attgaaaata tgggccgggt caattatggg cacaagctga cagcacctag
    13141 tcaaagtaag ggtctaggac gtggtatgat ggctgacttg cactttgtga ccaattggga
    13201 gatgtattgt ctgccgcttg atgatttgtc tcagctttgt tttgatggcg atttttacga
    13261 ggggcagccc ggcttttatc attatcaatt tgaatgtcat gagcctgagg caagctatat
    13321 tgatatgact ggctttggga agggttgtgt ctttatcaac aatcacccta ttggtcgttt
    13381 ttgggaagtg ggtcccttat taacccttta tattccaaag ggctatttca acaagggatt
    13441 aaatgacatt gttatttttg aaacagaagg tgtttaccag gatagtatcc gtcttgttga
    13501 taggccaatt agtatagatt atccgcaagc tgatgacagg actgatcaga cctagcattg
    13561 tcagttgagg cttgcagcat tgcttggttt tctatttaca gacactaaag gccacaacgt
    13621 gcccttgggc tggcaaacaa taggctagct caggggcttt gtctttgctt gctggattgg
    13681 cgggcgagat gtgcttttct gatgctatag cggcagtgac tgcaaaggct gttcgtgaga
    13741 gttgctttct ttatggatta tgcgtaaaat aagaatgata acagttctta tcaaaggata
    13801 gtcctttgtg ctcaagctta ttgaggtttt gggtggggct ttctaatagt agcttataga
    13861 aaggaagcgt gtttgtaaca ttgagactga gtaaagagtg ctaaaactgg ctggttctgc
    13921 tggttttggt tatgtggttt ctttgttagc gcgtttggta tctttaatta tgcctgaact
    13981 ccctgaggtt gagacagtgc gacgcgggct tgagcgctta gtcgttggca agcagattgc
    14041 agcagtgacg gttagggtgc ccaagatggt caaaacagac cttgagcatt ttgtgatgac
    14101 gatccctggg cagcaggtgc aaggggtaga tcgtcgcggg aagtacctgc tctttgactt
    14161 tggccagctg gttatgatct cgcatttgcg tatggagggg aaatacctct tgtttcctga
    14221 tacggtacct gagcataagc attttcatgt ctttttgaca atgactgatg gctccacgct
    14281 ggtttaccaa gatgtgagaa agtttggaac ctttgatttg ctaccaaagg ctgagctggc
    14341 tgcttttttc cagaagcgtc agcttggtcc tgagccgacg aagcagacct ttcaattgaa
    14401 gacctttgag gctgctctgc tagcctctaa aaagaccatt aagcctcatc ttttggatca
    14461 gactttagtg gctggtcttg gaaatatcta tgtggacgag gtgctatggg cagctagagt
    14521 acaccctgag cgtcgatctg ctagcctgaa aaaggcagaa atcaaacgga ttcatgatga
    14581 aacgattcgt attttacaat taggtattga aaagggtggc tcgacggtta gaacctatca
    14641 gaatacctta ggaatgaatg gtagtatgca gcattatttg atggtctatg gccaaacagg
    14701 caagccctgt cagcgctgcg ggacctccat tgtaaagctc aaggttggag gaagagggac
    14761 acatgtctgt cctaggtgtc agaagcaatg acaaaggtaa ttggcattac aggaggtatt
    14821 gcctccggaa aatcaacggc tgtcgcactt atcagacaag caggctacca ggtgattgat
    14881 gcggatcagg tggtgcatga gctgcaaaaa aagggcggca agctttatca ggtcctacta
    14941 gagacctttg gacaggatat tttattgcca tcggggcaat tagacagacc taagctagcg
    15001 gagctgctgt ttgctcattc ggaaaatatg gcgaaatctt cccagcagca gaatgctatc
    15061 attagggaag ccttagccaa gcaaaaagag gagctatctc aaacagaggc tattttcttt
    15121 atggatttac cgcttttagt tgagctgggc tatcaggatt ggtttgacgc tatttggctg
    15181 ctctatgttg atgaggagac tcagctcaag cgcctgatga agcgtaatca attgacagag
    15241 ctagctgcta ggcagcggat tgctagccag ctgccgatgt ctcagaaaag agcttatgct
    15301 gatttagtga ttgataatac tggtgatttt caggctttag agacacagat tagtaaggct
    15361 ctgcatgatt tagaggcgta agccttgcca tgctgttgcc ctagtctagt ggttttggag
    15421 cttctatagc gtatgcaaaa agccttatcg tacccattcg tggtgcgata aggcttttgt
    15481 gctgcattag atggaccatg cacgcattat atactagtgc tgtcttgcat tagcttattc
    15541 agcttattgc tttcttttgc gttttgccag gaagcctagt ccaagaagag agagtaagcc
    15601 tgtaccaagt gcagtcatca agctgccagt gtcatttgtt tttggtagtg ctttgccact
    15661 agattggcta gtagcgtttg acggcttggt tggtttttga ggttttgtct ctggcttagg
    15721 ctctggttta ggcattggtt caggcttagg ctctggttta ggtgccggat caggcattgg
    15781 ttcaggctta ggttcaggtt taggctctgg ttcaggctta ggctctggtt taggcattgg
    15841 ttcaggatct ggcttaggct taggatctgg ttctggttca ggcttagggt caagtttagg
    15901 aattagagta gaaccaagca ggttttgata aggtttatgt taataatttt tttctgtagt
    15961 tatatatata tctaaatgat attctggttt ttcttgtttt tgagctgctt cctcaccgac
    16021 tttaatcagc tccat
//
LOCUS       DARYXS010000044        15800 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.045, whole genome shotgun sequence.
ACCESSION   DARYXS010000044 DARYXS010000000
VERSION     DARYXS010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15800
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.045"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(419..2830)
                     /locus_tag="TV193_001146"
     CDS             complement(419..2830)
                     /locus_tag="TV193_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1513346.1"
                     /translation="MKKKHIVLGSAVAILLATNAASYQFGMHKALNSSSKDNSIAYID
                     SKDGKKALPKEKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHFHFYNGKVPYDAIL
                     SEELLMTDPNYQFKQSDVVNEILDGYIIKVDGKYYVYLKPGSKRKNIRTKQQIAEQVE
                     KGTKEAKEKGLAKVAHLSKAEVAAVNEARSQGRYTTDDGYIFSPTDVIGDMGDAFLVP
                     HGSHFHYIPKKDLSPSELVAAQAYWNNKQGGKPSVIGGQPLPGQGDQPRPYDIPVNPI
                     HHPAGNLPSVGDPSLSFADKTFGELLDQLHGLDKKYRHVKEDGLIFEPTQVTLANAFG
                     YVIPHGDHYHIIPREQLSALEITLADRYLAGQTQGSPIAKPKPATQDQTAKEVTHQFL
                     GHQIKAYGKGLDGKPYDTSDHYVFSKASISSVDKAGITAKHEEHFHYMGFGELEQEEL
                     DQVAQWLQEHGQADEIARALVQSDGKDMSFDAKHVSRKVTNGGKVGYMMTKDGKEYFY
                     DREHLDLTQIAFAEQELMLKDKQHYIYDIVDTGVQPKLAVEVSSLPMHAGNATYDTWT
                     SFVIPHIDHIHVVPYSWLTKDQIATIKYVMQHPNTRPDVWSNPNHDEAGGVIANVTPA
                     DQRTSMENWQIIHSAEEVQAAIKAGRYAAPDGYIFDPKDVLAEGTFVWRNDSFSIPRV
                     GGRSLRTITKDELSHDEWQKVQELLGNKTSDAAESTIKPTKDQEPSAQDTAADGIEQT
                     KSLFDDIPNYGLDRATLERQINQLAEIAGIKPEYLIFVPEGVKFYDQKGHLMLYDVTT
                     LQQIK"
     gene            complement(2845..3768)
                     /locus_tag="TV193_001147"
     CDS             complement(2845..3768)
                     /locus_tag="TV193_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1513347.1"
                     /translation="MKRKWIHLTLLLALFSGLVACSKPKEQSKQSRGMTIVTSFYPIY
                     AMTKAVSGELNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWADDLDPN
                     LKKSKVAVFEASKSLTLDRVTGLEDIEVTDGIDPATLYDPHTWTDPILAGEEALAIAK
                     ELSRLDPKHEAIYTENAQAFQKEAKELADEYTKKFKKTSSKTFVTQHTAFSYLAKRFG
                     LKQLGISGISPEQEPTPRQLTEIQDFVKEYKVKTIFAEDNVNPKIAKAIAKTAGAKVK
                     LLSPLEAAPKNNKSYLDNLRANLEALYQSLK"
     gene            complement(4095..5642)
                     /locus_tag="TV193_001148"
     CDS             complement(4095..5642)
                     /locus_tag="TV193_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1513348.1"
                     /translation="MKKQSLKKVSLLTVTVISSLALAANANTYTTYARDNVVTATSQA
                     AEGFDFVATILDSNGRALEGKTVVLLDTTANPAKQVASAVSNSNGQAIFTQLPLNINL
                     SVSVDGETKGYTVRTSLAGSKEAASFVAKGAGTKEPLYSKNVIDITVRNQDSEPLEGQ
                     TVTLKIRQGQLVGSLVSDKNGKVTFKDRLLDGTFYHYELNGKYIGQVMTKMSVNAYLD
                     TSSSSSSGTSPQSKDTPKQEDGKSSPLEEGFHFVVTALDKEDRVVAGKEVSLTALIDG
                     AKTTIASAKTNADGQAVFTKLPLSRNISVSIDGKLQGYTVRTSESNEHKAAAFYVDGK
                     GTKPVVYSKTPAIVTVYDANGNKLAGQEVVLKNRYGAIRAIGKTDQSGKATFVNQLMD
                     GMFYEIVINGVKIPKKASTGSDVSGFLTKAQIRTDNKLSESERHSKDTKPLGKEPKDP
                     EKDKNVAKPETKSSSNRNVAPKEGKKETKALPRSGESAAPMVAFMGVLLIGLAAVIGL
                     VTKRRSS"
     gene            complement(6267..7148)
                     /locus_tag="TV193_001149"
     CDS             complement(6267..7148)
                     /locus_tag="TV193_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1513349.1"
                     /translation="MKKALLIVNPSSGGEKAKEYEALAYDKLASYFDDVDVKHTEKGG
                     DAKRFAHEAAQQRLDSVFVMGGDGTVNEGISGLAEQDYRPKFGFFPLGTVNDLARALG
                     MSLDPEEAINQISFETTSPLDIGKVNDAYFMNVVAIGTLPEAINDVAPEEKTTFGKMA
                     YFMSGFKQLIKNKSYTFQLDIDGKTKEINSTTLLIGLTNSIGGFERILPEARVDDGLL
                     HLIYLKDSNLLETVKALPSLLKGVEASDQTLGYQTFKEATIAMKEGQLSINVDGDEGE
                     ALPITVKVLPQHLQVYR"
     gene            complement(7313..8314)
                     /locus_tag="TV193_001150"
     CDS             complement(7313..8314)
                     /locus_tag="TV193_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1513350.1"
                     /translation="MVTLKDIAALAKVSPATVSRVLNKDQSLSVGQETKHRILTIADE
                     LGYQKHLKATNSPKSKLKIAIVQWYSQEEELNDLYYYAIRIGIEKRAYELDYDIVRYF
                     NNDILRVSDDHAGIIAIGKFSACQIKELEALSQHLVFVDSDTLELGHPCVTTDFDNAV
                     LKVLDYFMSKGIYSIGMIAGEEKTTDGREALVDQRFRTYKNYASEHGIYQPRYVYIGP
                     FSAQSGYELMTQAIEELGDDLPKAFFIANDTLAIGALRALQERGLAVPERVELISFND
                     TPLTRQVFPALSSVTVFTEDMGRMAVDVLNRNILNPERVKTMTILATELTLRDSTIG"
     gene            8455..9627
                     /locus_tag="TV193_001151"
     CDS             8455..9627
                     /locus_tag="TV193_001151"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEL1513351.1"
                     /translation="MDIAQLKQSFTDVFGKEPDAVFFSPGRINLIGEHTDYNGGHVFP
                     AAISLGTYGLARKREDQQLRFFSANFEEAGIIEVDLNQLTFDQADLWANYPKGVLSFL
                     QKAGHLIDTGFELYVFGNIPNGSGLSSSASLELLTGIVAQELFGLDVERLDLIKIGQQ
                     AENHFIGVNSGIMDQFAIGMGADKQALYLDTNTLAYEAVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEQALEELNALLDIKALGELDAQRFDEYSYLIKDGKRLKRARHAVL
                     ENQRTLQARQALEAGALEQFGRLMNASHVSLEHDYEVTGPELDTLVHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVAKDKVDSFIETVGKAYTKVIGYAPAFYLAEIAQGARLLSRK"
     gene            9631..11115
                     /gene="galT"
                     /locus_tag="TV193_001152"
     CDS             9631..11115
                     /gene="galT"
                     /locus_tag="TV193_001152"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEL1513352.1"
                     /translation="MASLIDTFVRKVIEHSDYTSEDAIYIRNRVLALVGENHVWQETS
                     LTALIALKEALVELAAENGKIGRLPEEKDCLGAELMNMITPIPSVVNRRFWDTYAQSP
                     QQAISDFYQLSQLNDYIKTAAIAKNISFTVPSQYGDMAITINLSKPEKDPKAIAAAKK
                     AKASSYPKCQLCMENEGYQGRINHPARANHRIIRMSLGNEAWGFQYSPYAYFNEHSII
                     FNTEHVPMTISTSTFRQLLDIVDILPDYFVGSNADLPIVGGSILTHNHYQAGRHVFPM
                     EIAKQDKRFTFKGFPDIQAATLNWPMSVIRLRSSNKDQLVQLADTIRLAWRHYSDDSV
                     DIVAYTNQEPHHTITPIARKKEGQFELDLVLRDNHTSEQFPDGVYHPHADVQHIKKEN
                     IGLIEVMGLAILPPRLKEELVEVKKYILNQANQIADYHKDWADQITLRPDLSAITVDD
                     IIQEEVGSVFVRVLEDAGVYKRDQEGQAAFMRFLKSIGIEAIEE"
     gene            11125..12135
                     /gene="galE"
                     /locus_tag="TV193_001153"
     CDS             11125..12135
                     /gene="galE"
                     /locus_tag="TV193_001153"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1513353.1"
                     /translation="MTVLVLGGAGYIGSHTVDWLISQREEKVIVVDSLVTGHRKAVHP
                     EALFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLVAESMADPLKYFDNNTAGMIKL
                     LEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
                     YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPD
                     GTNVRDYVHPIDLADAHILAMAYLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAI
                     PAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKAS
                     GS"
     gene            12212..13255
                     /locus_tag="TV193_001154"
     CDS             12212..13255
                     /locus_tag="TV193_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEL1513354.1"
                     /translation="MNIYQDIIEYIDQVPVTQLRLINTNGVEAHLLTLGATLQAFLVS
                     NEKQPKNIILGHDRPSDYLKNPLCAGQTIGRVAGRIKRGSFQLEQQRVCVDTNENGHC
                     LHGGFKGFHKLHWPYDTRQTVDYLEVTFKRDILEADDHFPGDLTVSITYRLDNHNRLS
                     IHFKAHSMRGTSLFNPTNHVYFNLGQTQDLTNHNLYIAASHRIETDNELIPTGQKLAV
                     DQTVYDFRSIKSLYPAIVENNGFDTAFEIDQQAIGTTKPIAVLQDSVSHDQISIYSDR
                     NALVIYTMDSIQDGLYFGRDQGKEGLAREGIAMEAQTLPDAIHHNQFGDIILKEGGTK
                     SYTICLAYEHLPD"
     gene            13556..13699
                     /locus_tag="TV193_001155"
     CDS             13556..13699
                     /locus_tag="TV193_001155"
                     /inference="COORDINATES: protein motif:HMM:NF013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1513355.1"
                     /translation="MIFDKDTNLKHKHRHQKFWYMGYYGDTAGKNLKTIAKYISNHYR
                     KIG"
     gene            14334..14474
                     /locus_tag="TV193_001156"
     CDS             14334..14474
                     /locus_tag="TV193_001156"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1513356.1"
                     /translation="MEPTNKTIKDMKEQAFGFRNFKNFKVKIPNALNITKEETKFISS
                     RA"
     gene            complement(15066..15404)
                     /locus_tag="TV193_001157"
     CDS             complement(15066..15404)
                     /locus_tag="TV193_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1513357.1"
                     /translation="MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISI
                     LEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVFYLIRQSRVDILRIRSTKTDYLN
                     DLENLFNNIL"
     gene            complement(15394..15681)
                     /locus_tag="TV193_001158"
     CDS             complement(15394..15681)
                     /locus_tag="TV193_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEL1513358.1"
                     /translation="MATLIRDRQYNFRVNTEMMEEAKRILEAKNISVPDALNLFVERV
                     VEEKDLPIKTAEQIRAESFLNELISELDEGYQDILAGRTKPANEVFSKYGL"
BASE COUNT         4592 a         3527 c         3106 g         4575 t
ORIGIN      
        1 aattgtacgg ctgctaacct ttttcctaac ccttttagac accaaaaaac tccccttatc
       61 gtttttagtg attgtttttc actgtccact ttaaagggga ggtctagcta ttaaaggcta
      121 ggcggttttg actggaggac tattaggtgt gaggttaatt ggtaaaaact ctttctgtgc
      181 tgccctcctt aggtcatata gactttcttg gaaccaaaac ccacatatag cctacagaga
      241 tccaatgctt taaaagctat gaggtgctaa gctgctgatc aagtcagctt ctctgactgt
      301 tgctgcaagc aaaagcctac taagcgatct taggctgtga ggcgtaagaa caggtcatca
      361 taccaatagc tttttgggga taagctgtga tttgtatgcc ttagctattt tatagtgttt
      421 atttgatttg ttgcaatgtt gtcacatcat aaagcattag gtgtcctttt tggtcataga
      481 atttgacacc ctctggcacg aaaataagat actccggttt aatgcctgct atttcagcta
      541 actgattgat ctgacgttca agagttgccc gatctaaacc ataattagga atatcgtcaa
      601 ataaagactt ggtctgctct atgccatctg cggcagtatc ttgcgctgac ggttcctggt
      661 ctttggttgg cttaatagtg ctttcagctg cgtctgaggt cttattgcct aataattctt
      721 gaaccttttg ccattcatca tgagataact catctttagt aatggttctt aaagagcgtc
      781 caccaactct aggaatgcta aaggaatcat tacgccaaac aaaggttcct tcagcaagaa
      841 cgtccttagg atcaaaaata tagccatctg gagctgcgta ccgacctgcc ttgatagctg
      901 cttggacctc ttcggcagag tgaataattt gccagttttc cattgaagta cgttgatcag
      961 ctggtgtgac attagcaatg actcctccag cttcatcatg atttgggtta gaccaaacat
     1021 caggacgagt attagggtgc tgcatgacat atttgatggt cgcaatctga tccttagtta
     1081 gccatgaata aggtacaaca tggatatgat cgatgtgagg aatgacaaaa gatgtccatg
     1141 tatcataggt tgcattacca gcatgcatcg gtaggctgga tacctctaca gctagctttg
     1201 gctgaacgcc tgtatcaaca atgtcataaa tatagtgttg cttatcctta agcatgagct
     1261 cttgctctgc aaaggcaatt tgtgttaggt ctaaatgctc acgatcatag aaatactctt
     1321 tgccatcttt tgtcatcatg taaccaacct taccgccatt ggttaccttg cgactgacat
     1381 gcttagcgtc aaaggacatg tctttaccgt ctgattgaac taatgccctt gcaatctcat
     1441 ctgcttgacc atgctcctgc agccattgtg caacctggtc aagctcctct tgctctagct
     1501 caccaaagcc catgtaatgg aaatgctcct catgcttagc tgtgatgcct gccttatcaa
     1561 cagaggaaat agatgcctta ctaaagacat aatgatcact cgtgtcataa ggcttgccat
     1621 ctaagccttt accataagcc ttaatctgat ggccaaggaa ttgatgtgta acctcttttg
     1681 cagtctggtc ttgagtagct ggctttggct tagctattgg actgccctgc gtttgacctg
     1741 ctaggtaacg atcagccaag gttatttcaa gggctgacaa ttgctcacga ggaataatat
     1801 ggtagtgatc tccatgagga ataacatagc caaaggcatt ggcaagggtc acctgagttg
     1861 gctcaaaaat gagaccatct tccttgacgt gcctgtattt cttatccaag ccatgcaatt
     1921 gatccaacaa ttctccaaag gttttatctg caaatgatag gcttggatct cctactgacg
     1981 gcaaattccc agctgggtgg tgaatcgggt taacaggaat atcatatggt ctaggctgat
     2041 ctccttgacc tggtaaaggc tgaccgccaa taacacttgg ttttccgcct tgcttgttat
     2101 tccaataggc ctgcgctgct actagctcac ttggggataa gtccttttta ggaatatagt
     2161 ggaagtgact gccatggggc actaaaaagg catctcccat gtctccaata acatctgtcg
     2221 ggctaaagat atagccatca tcagttgtat agcgtccttg acttcttgct tcgttaacag
     2281 ctgccacctc tgccttactc aagtgggcaa ccttagccaa gcctttttcc ttagcttcct
     2341 ttgttccctt ttcaacctgc tcagcaattt gctgcttggt acgaatattt ttacgcttgc
     2401 ttcctggctt tagataaaca taatacttgc catcaacctt gataatatag ccatctagaa
     2461 tctcgttaac aacatcagac tgtttaaact gataattggg gtccgtcatt aatagctctt
     2521 cactaagaat agcatcatag ggaaccttac cattgtagaa atggaaatga tcaccatgtg
     2581 aggttacata gccttgatct gtgattttaa caacgatttg ctctgcagag atcccctctt
     2641 ctgcgctgat ttgatccatt gttttttctt tggggagggc ttttttgcca tcctttgaat
     2701 caatataggc aatgctatta tctttagatg aggaatttag agccttatgc attccaaact
     2761 gatatgaagc agcattagta gccaataaaa tggccacagc tgatcctaaa acaatatgct
     2821 tctttttcac gttttcatct ccctttattt taagctttgg taaagagctt ccaaattagc
     2881 tctcaaattg tctagatagg acttgttgtt tttgggcgct gcctctagtg gactgagcag
     2941 cttgaccttt gctcctgctg ttttagctat cgccttagca attttaggat taacattatc
     3001 ctctgcaaaa atcgttttta ccttatattc tttaacaaag tcttgaattt cagttagttg
     3061 gcgaggagta ggctcttgct ctggcgaaat accagaaata cctaactgct ttaagccaaa
     3121 gcgttttgct agataagaaa aggctgtgtg ctgtgtgaca aaggttttag atgatgtctt
     3181 tttaaacttt ttagtgtact catcagccag ctcttttgct tccttttgga atgcttgagc
     3241 attctcagtg taaatggcct catgcttagg atctaaacga ctgagctcct tagcaatagc
     3301 gagtgcttct tcacctgcta aaataggatc tgtccaggta tgaggatcat acagggtagc
     3361 agggtcaatg ccatctgtca cctcaatatc ctccaaacca gtaacacgat ctaaggttaa
     3421 agatttggaa gcttcaaaaa cagcaacctt tgatttcttc aaattaggat ccaaatcatc
     3481 agcccaggcc tctagggtgt gagagtgata aacaaataaa tcagcatcgt aaatggcagc
     3541 aacgtcattt acagatggct caaaggaatg aatacctgcc cctgactgaa tcatccgaac
     3601 atcgtttagc tcaccagata ccgcctttgt catggcgtaa ataggataaa agctagtgac
     3661 gatcgtcatg cctcttgact gcttgctttg ctccttgggc ttgctacagg caacaagacc
     3721 tgaaaaaaga gcaagcaaca gtgttaaatg tatccatttt cttttcatat aatctccttt
     3781 gctcattaac cagttatgaa ccggttaatt ttaacagctt tagatgtatt tgtcaaattt
     3841 tttaataaaa aataaaagcc attaaaacga tggcttaatc agcccctaac ctgcttaacc
     3901 tttataagaa gccatagctc tatgataaac tgtggtctgt gacgcatgac ctcactgtct
     3961 gttatcttac tgttgcatga tacgtttaaa aaagatttag ccttcttttt ttagattgta
     4021 gaacggcgct gaacaatcac ttaaccgtca aaaaaacgcc ttgatagctg caagacgttt
     4081 ttacttattt ggttttagct agagcgacgt tttgtcacaa gaccgatgac agctgcaagg
     4141 cctattaata gaactcccat gaacgctacc atcggcgctg ctgattcacc agatcttggc
     4201 aaagccttag tctctttttt accttcttta ggggctacat tacggtttga cgaggacttg
     4261 gtttctggct tagcgacatt cttatccttt tcaggatcct ttggctcctt gcctaagggc
     4321 tttgtgtctt tagaatggcg ctcagactcg ctgagtttat tatcggttct gatttgagct
     4381 ttggttaaaa agccgctgac atcactaccg gtagaggctt ttttaggtat cttgaccccg
     4441 ttgataacaa tctcataaaa cataccgtcc atgagctgat tcacaaaggt tgccttacct
     4501 gattgatcag ttttgcctat tgccctgata gctccgtatc gatttttcag cacaacctct
     4561 tgccctgcca acttatttcc attggcatca taaacagtta ctatggctgg tgtcttagag
     4621 taaacaacag gctttgttcc tttaccgtcg acataaaaag cagcagcctt atgctcatta
     4681 gactcactcg tgcgaacagt atagccctgt agcttaccat caattgagac actgatatta
     4741 cgtgatagtg gtagtttggt aaagactgct tgaccatcag catttgtctt tgctgaagca
     4801 attgtcgtct tagcaccgtc tatcagagca gtcaagctta cctccttgcc tgcaacaacc
     4861 ctatcctctt tatctagggc agtgacaaca aaatgaaagc cttcctctag cggacttgac
     4921 tttccatcct cctgcttagg agtgtccttg gactgaggtg acgtacctga tgacgagctt
     4981 gatgaggtat caaggtaagc attaacagac atttttgtca tgacctgccc tatatactta
     5041 ccattaagct cataatgata aaaggttccg tccaacaaac gatccttgaa ggttaccttt
     5101 ccatttttat ctgagacaag acttcccacc agttgaccct gacgtatttt tagggtgact
     5161 gtttgccctt ctaagggctc actatcttga tttcggaccg taatatcaat gacattttta
     5221 ctataaagag gctcctttgt ccctgctccc ttagcgacaa agcttgctgc ctctttagat
     5281 ccagcaagac tggttctcac tgtatagccc ttggtttccc cgtcaacaga aacactcaaa
     5341 ttaatgttta agggtaattg agtaaaaata gcctgaccat tgctgttaga gacagcagaa
     5401 gctacctgct tagcgggatt agctgtcgtg tctaacaaga caactgtttt tccttcaaga
     5461 gcacgaccgt tgctatcaag tatcgtggca acaaaatcaa aaccctcagc cgcttgcgac
     5521 gtcgcagtga caacgttgtc tctggcataa gtcgtatagg tattggcatt ggctgccaag
     5581 gccaagctag atataacagt aaccgttaaa agactgactt ttttcaatga ctgtttcttc
     5641 ataaaaaagc tcctttattt tgattaacta gcctagtttt aatgggaaat atccccttga
     5701 taccctttct gaggtgatag gaacagcagc aatctctctt agcctatgat gcctaagctt
     5761 taaagctaag ttttcaaagt ccacctaagg ggctacatgc cacaacaaaa agcatcagat
     5821 gaacagacat ctagaggcaa cagccgatct aagataatag ttagtagcca ttttagctac
     5881 tctcaaggct gtcgccgcag tgatgatgtg attgtctatg ctttttaata aaacttaact
     5941 agttaagatt tttgtgctgc tatcctatca aataaccccc gccaagtcaa caacaatgct
     6001 cataccacag caagcaaagc attttgatga tgactgaaca gccaaatcag ccaagcccca
     6061 ggcagcaaaa aagaggattc aaaccaaatc ctctctctac taagcctgct gctgttaacg
     6121 tatcatgcta aaggcaaatg gtatagccac gctgatatga aggtctgatt aacagctacg
     6181 acggacacgc ttgttaaggc taccattgct aatcacacta ggtcatatcc tccaccgtat
     6241 aagaatgact aacttcatta ttcagattaa cgatatacct gcaggtgctg aggaagtacc
     6301 ttgacagtga ttggtaaggc ctcaccctca tcaccgtcca cattgataga tagctgtcct
     6361 tccttcatgg caatagtggc ctccttgaag gtttgatagc caagtgtttg atctgaagcc
     6421 tcaactccct tcaataggct aggaagggcc ttcaccgttt ctaatagatt gctatccttc
     6481 agatagataa ggtgcagcaa accatcgtcc acacgtgcct ctggcaaaat ccgctcaaag
     6541 cccccgattg aattggtcaa gccaatcaag agtgttgtgc tgttgatttc ttttgttttg
     6601 ccatcaatat ctagctggaa ggtatagctt ttatttttga tcagctgctt aaagcctgac
     6661 ataaaataag ccattttccc aaaggtcgtc ttctcctcag gggcaacatc attgatcgcc
     6721 tctgggagcg tccctatggc aacaacattc ataaagtaag catcgttgac cttaccaata
     6781 tccagaggac tggttgtctc aaagcttatc tgattaatcg cttcctctgg gtctaacgac
     6841 atgcccaagg cacgtgccaa atcattgact gttcctagag gaaaaaagcc aaacttaggg
     6901 cgatagtcct gctctgcaag cccgctgatc ccttcattga ctgttccatc acctcccatg
     6961 acaaagacac tgtccagccg ctgctgggct gcctcatgag caaaccgttt ggcatctcct
     7021 cctttttcag tgtgcttaac gtcaacatca tcaaaatacg aagctagttt atcataggct
     7081 aaggcttcat attccttggc tttctcacca cctgagctag ggttaacaat caatagggct
     7141 tttttcattt atgatatcct acattttcta ttatatttca cgactattat aatcattatt
     7201 caaaacatcg tcaaataata ctcactatgt cattagtcag tcttaaagct tctaatatgg
     7261 ttgccgtcta gtgtttcatt ttactgaact ctttacccag ctagctcaat gcctaaccaa
     7321 tcgtgctgtc tcttaaggtc aactctgtcg ccaatatcgt catggtcttg acacgttctg
     7381 ggttaaggat attcctatta agcacatcaa cagccatacg tcccatatcc tctgtaaata
     7441 cagtcacact agaaagcgca ggaaagacct gtcttgttaa aggagtatcg ttaaaggaga
     7501 taagctcaac acgctcaggc accgcaagcc ctctttcttg gagagctctt agagcaccta
     7561 ttgcaagggt atcattagca ataaaaaatg ctttaggcaa atcatcacct agctcctcaa
     7621 ttgcctgtgt cataagctca tagccagatt gtgctgaaaa aggaccgata tagacatacc
     7681 tcggctgata aatcccatgc tcagaggcat aatttttata ggtgcgaaag cgctggtcca
     7741 ctaaagcttc tctaccgtca gttgtctttt cctcaccagc aatcatgcca atgctataaa
     7801 tccctttgct cataaaataa tcaagaactt tcagcactgc attgtcaaag tcagttgtga
     7861 cacaggggtg gcccaattca agcgtgtcac tatcaacaaa caccaaatgc tgggataagg
     7921 cttcaagctc cttgatttga caagcgctaa actttccaat agcaataatc ccggcatggt
     7981 catctgaaac cctcaaaatg tcattgttga aataacgaac aatatcataa tccaattcat
     8041 aagctctttt ttcaatgcca atgcggatcg cataatagta gaggtcattg agctcctctt
     8101 cttgagaata ccattgaaca atagctattt ttagctttga tttagggcta ttcgtcgctt
     8161 ttaaatgctt ttggtagccc agctcatcag caattgtgag aatgcggtgc tttgtctctt
     8221 gaccaacaga caagctttgg tccttattta aaactctaga aacagttgca ggagaaacct
     8281 ttgccagagc tgcaatatcc ttaagcgtta ccatatcaaa ccttctttct gatttcttct
     8341 agtatatcac aagcattttc aaaagcaata tttagtaaaa ttttagtaaa aatgttgacg
     8401 agcagcttag cgaagcgtaa aatcaagcta tcaacatcgt taaaggagcc gctaatggat
     8461 atcgcgcaac ttaagcaaag ctttactgac gtttttggca aggagccaga tgctgtcttt
     8521 ttctcaccgg gtcgcatcaa cctcattggt gagcacactg attacaatgg tggacatgtc
     8581 tttccagctg ctatcagtct gggaacctat gggctggccc gcaagcgtga ggatcagcag
     8641 ctgcgctttt tctcagcaaa ttttgaagag gctgggatta ttgaggttga cttaaatcag
     8701 ctgacctttg atcaggctga cctttgggct aattacccta agggagttct ctcctttttg
     8761 caaaaagctg ggcaccttat tgatacgggc tttgagcttt acgtttttgg caacattcca
     8821 aatgggtctg gtctgtcctc ctcggcatca ctggagcttt tgacaggtat tgtggcacaa
     8881 gagctgtttg ggcttgatgt ggaacggtta gatctgatta aaatcggtca gcaagctgaa
     8941 aatcacttta tcggggtgaa ttcaggtatc atggaccaat ttgccatagg catgggagct
     9001 gataagcagg ctctatacct tgataccaac accttagcct atgaggctgt tccgcttgac
     9061 cttggtgatc acgtgattgt catcatgaat accaacaagc gccgagagct agccgattca
     9121 aagtataatg aacgccgagc agagtgtgaa caagcccttg aggaattaaa tgcccttctg
     9181 gatattaaag cactggggga attagacgct cagcgctttg atgagtacag ctaccttatc
     9241 aaagatggta aacgtctcaa acgcgctcgc cacgctgttt tggaaaatca acgaacactc
     9301 caagcaagac aggcccttga agcaggagca ttggagcaat ttggtcgtct gatgaatgct
     9361 tctcatgtat ccttggagca tgattatgag gtcacaggcc ctgagctgga cacactggtc
     9421 cacaccgctt gggagcaaga aggggtccta ggggctcgca tgacaggagc aggctttgga
     9481 ggctgtggca ttgctatcgt ggctaaggat aaggtagata gctttatcga aacagttggc
     9541 aaggcctata ctaaggtcat tggctatgct ccagcctttt atctggctga gattgctcag
     9601 ggagcacgac tactttcaag gaaataagat atggcaagct taatagacac ctttgtaagg
     9661 aaggtgattg aacacagcga ctacacatca gaggacgcta tttatatccg caatcgggtt
     9721 ttagcattgg ttggtgagaa ccatgtctgg caagaaacct ccttaacagc cttaatagct
     9781 ctcaaagaag cattggttga gctagctgct gaaaatggca aaataggcag gcttcctgaa
     9841 gaaaaggact gcttaggagc tgaattaatg aacatgataa cccctattcc aagtgtggtt
     9901 aatcgtcgct tctgggatac ctatgcacaa tctcctcaac aggctatctc agatttttac
     9961 cagcttagtc agctaaatga ctacatcaaa acagcagcaa ttgccaaaaa catctccttt
    10021 acagtgcctt ctcaatatgg tgatatggct attaccatta acctatcaaa gcctgaaaag
    10081 gaccctaagg ccattgcagc cgctaagaag gctaaggcat cctcttatcc aaaatgccag
    10141 ctttgtatgg aaaacgaagg ttatcaagga cggattaacc acccagcccg agctaatcat
    10201 cgcattatcc gtatgagctt aggcaatgag gcttggggat tccagtattc accctacgct
    10261 tattttaatg agcacagtat tatttttaat actgagcatg tgccaatgac aatcagtaca
    10321 agcaccttta gacagctcct tgatattgtt gatatcctgc cagactattt tgtcggctct
    10381 aatgctgatc tgcctattgt tggcggctct attttgaccc acaaccatta tcaggccggt
    10441 cggcacgttt ttccgatgga aatcgcaaaa caagacaaac gctttacctt taaaggattt
    10501 ccagacatac aggctgccac tctcaactgg cctatgtcag ttatccgact gcgcagcagc
    10561 aacaaagatc agctagttca attagcagac acgattcgac tggcttggcg tcattattct
    10621 gacgacagtg ttgatatcgt cgcttatacc aaccaagagc ctcaccatac catcacacct
    10681 attgccagaa aaaaagaagg gcagtttgaa ttagacttgg ttctacgtga taaccatacc
    10741 tctgagcaat ttccagacgg tgtttaccac ccacatgccg atgtgcaaca cattaagaaa
    10801 gaaaacatcg gccttattga ggttatgggg ctagctattt taccaccgcg cctcaaagag
    10861 gaattggttg aggtcaaaaa atatatcctc aatcaagcca atcaaatcgc agactaccac
    10921 aaggactggg ctgatcagat cacattacga ccagatctct cagcgataac tgttgatgac
    10981 attatccaag aagaggtcgg ctctgtcttt gttcgtgtcc ttgaggacgc tggcgtctac
    11041 aaacgtgatc aagaaggtca agcagccttt atgcgttttc ttaagagcat tggcattgaa
    11101 gcaattgaag aataggagga aaaaatgact gttctagttt taggcggtgc aggctacatt
    11161 ggatcacata cagtggactg gctaatatca cagagagaag aaaaagtcat tgttgttgat
    11221 agcttggtga cagggcaccg taaagccgtt cacccagagg ctctgtttta caaaggagac
    11281 ttagcagaca aagcctttat gcgtcaagtc tttagggaca atccagacat agacactgtg
    11341 attcactttg ctgcctcttc cttggtcgca gaatcaatgg cagaccctct gaaatacttt
    11401 gacaataaca cagcaggtat gattaagctg cttgaggtca tgagagaagc caaggttaag
    11461 cgcattgtct tttcatcaac agcagccgtc tatggcattc caaaaacagt ccccatctta
    11521 gagtcagcgc ctaaatgccc aatcaatcct tatggccaaa gcaagcttat gatggaaacg
    11581 ataatgacct gggccgacaa agcctatggc atcacatttg tggcccttcg ctacttcaat
    11641 gttgccggag caaagccaga tggctccatc ggtgaagacc acgagccaga aacacattta
    11701 ttacccatta tcctacagac tgcacaggga gtgcgtgagc aggtgatgat ttttggtgat
    11761 gattatgaca caccagatgg tactaacgtt cgagattacg tccatcctat cgatttagct
    11821 gatgcacaca ttttagcgat ggcatacctg cgtcagggca aaccatcaca ggtctttaat
    11881 ctagggtctc aaacaggctt ttccaatcgt caactgcttg aagccgctcg tcgggtaaca
    11941 ggacaagcca taccagccaa aaaagctgca agacgtcccg gtgatccaga caccttaatt
    12001 gcgtcatcag aaaaagcacg caaggttctc aattggaagc caagctatga cgatattgac
    12061 aagataatcg catcagcctg ggcctggcat accaagcatc caaaaggata tgacgataaa
    12121 gcaagtggca gctagtccct caagacagct accacagcaa gtagtcagcc tcccttaatt
    12181 catacaccta tactaatagg agaaacaaac tgtgaacatt tatcaagaca tcattgaata
    12241 catcgatcaa gtgccagtca cccagctaag actgattaat actaacggtg ttgaggctca
    12301 cctattgaca ctaggagcca ctctacaggc ctttctagtg tcaaatgaaa agcagccaaa
    12361 aaatatcatt ttgggacatg accgaccaag tgactaccta aaaaatcctc tttgtgcagg
    12421 gcaaaccatt ggccgagtag caggtcgcat aaagagagga agctttcagc tagagcagca
    12481 aagggtttgt gttgacacca atgaaaatgg gcattgcctg catggaggct tcaagggctt
    12541 tcataagctt cattggcctt atgatacccg ccaaacagtt gattaccttg aagtaacctt
    12601 taaaagggat attttagaag cagatgacca tttcccaggt gacctgaccg taagcattac
    12661 ctaccgtcta gacaaccata atcgtttaag cattcacttt aaggctcata gcatgagagg
    12721 cactagccta ttcaatccaa ccaaccatgt ttattttaat ttagggcaaa cacaagactt
    12781 aaccaatcac aacctataca tcgcagcatc acataggatt gaaacagata atgagctaat
    12841 cccaacaggt caaaagctag cagttgacca gacggtctat gattttagat caataaagtc
    12901 cctctatcct gctattgtcg aaaataatgg ctttgatact gcctttgaaa ttgatcagca
    12961 ggctattgga acaaccaaac ctattgctgt cttacaagac agcgtcagcc atgaccaaat
    13021 cagcatctac tctgaccgaa acgcactcgt catttatacc atggacagta tccaagatgg
    13081 cttgtatttt ggaagagatc agggcaagga gggactggct cgtgagggga tcgctatgga
    13141 agcacaaacc ctgcctgatg ctattcacca caaccagttt ggtgacatta tcctcaaaga
    13201 aggaggcacc aaaagctaca ctatctgcct agcctatgag catctgccag attaacataa
    13261 gtacagccaa gctttaatga aataacaaga ccttgatttt tttgaattgc accccaaccg
    13321 ttagccaaaa actctaacaa gcgaggatca gttcattcat caaggtcttt tcctcttttt
    13381 atctataggc gttacaaagt agatatagga acatcatacc aaatatgtgg aatgctaaga
    13441 gcttatcatc acaaagcgaa tacatgttcc gactacatct atgcattagt aagtcttttt
    13501 cctaaacgaa gtgttgccag ctttatgaga tacttaaaag tataagagca gcctaatcat
    13561 ttttgacaaa gacaccaacc ttaagcataa acataggcat cagaaatttt ggtatatggg
    13621 ctattatgga gacacagctg gtaaaaatct aaaaacgata gccaaatata tttcaaatca
    13681 ctataggaag atagggtagc aaaccaactg acatcatttg agaccattga tccatttaca
    13741 ggccaaccaa ataagaaaaa gtaacctttt gattgaactc ccgctcggaa aagtggagcg
    13801 cgagtattca atgacctcgt tatcctcgac cgatgagagc agcttatagt cacagtataa
    13861 agaggctgga acagacaacc tcttttgatt gacaataagt gtttgatagc attgtatggg
    13921 attactttca catcattcag cacctgggtc gagctttgat gaccgccaga attgatagcc
    13981 attatgaagg gctttgagca gccatttctg ctttatcgaa ccataaaata tcattgatga
    14041 ctgctccaaa aggacagtca taaactgtct gatcagcgct tctagtcacg aacctttaag
    14101 caaaccttaa tactcaaaaa aggtaagtca gaaaatactt gatttctcag atgagctgtg
    14161 gaattaccac gacctttacc agctcttgct ctttcatttt caaaaagtgg gtaaccgagt
    14221 ttttcgggct gattgaagag ctttaagctt ggtcaatcat cacgttttaa ccgtcctcaa
    14281 aatctttttg aaatacaaac cctacatcac aaatgcctta ttccaatgct aaattggagc
    14341 ccactaacaa gactattaag gacatgaaag agcaagcctt tggatttagg aactttaaga
    14401 acttcaaagt caagattccc aatgctttaa acatcacaaa agaagagaca aaatttatct
    14461 cttctcgtgc ttagctatca gtcacccact gcagttgaca ttgagccaaa ttatagagcc
    14521 attttcgtag aaagcacaga aaaaacaccc atgaggtaaa ctcttgagtg ctttgaaacg
    14581 ttgatataat gcgatatatt aacgttttga ggcacggaga ctgcgtctcc tttgcagccg
    14641 tattcgtaag cgactaaagc cgcaacgact acgtcaattg cgtcgccagt tctttcaaaa
    14701 aagaaaatac cccatggtaa cccatgaagt attgttctgc tgtattgtag ctggttctta
    14761 acgttttgag aactgactag ctttacgagc tttcttaaga cctggttttg ggtgacaaaa
    14821 accaaatatc tgtaaaagct tatcaaatca agctttcaaa actcattttc attaaatata
    14881 agcactttta acccaatcct acaaataata gattaccatt agattaccaa aactcagttt
    14941 tcggagctta tgtagttgag aaaatctcgt atttactttg cttttatata tccactttat
    15001 actatcatcc cgtcataaca gagcatgatt aaatagttac ataaaaaaca atacttactc
    15061 tatcattaaa ggatattgtt aaaaagattc tctaaatcat ttaaataatc agttttagta
    15121 cttctaatac gaagaatatc tacccttgac tgacgaatta aataaaatac tatgaaatgc
    15181 ttactaggaa tcatccttag ctggccttca ggaaatagtt tacgtcctac acgatcgtca
    15241 aaatcaacat aaccttcagg ggatatctca agaatagaaa tagctgactg caaagattca
    15301 ataacttttt gagcgcttga gtgcgaaaat tctgttaaat agtagttata gatttcatct
    15361 aaatcttgtt ctgccttatt tgaaatatag atatcataag ccatattttg aaaatacctc
    15421 attagctggc ttcgtacgtc ctgctaaaat atcttgatac ccttcatcaa gctctgatat
    15481 cagttcattt aaaaatgatt cagctctaat ttgttctgca gttttaatag gtaaatcttt
    15541 ttcttccacc acccgttcaa caaatagatt aagagcatct ggaacactaa tatttttagc
    15601 ttctaaaata cgctttgctt cttccatcat ttccgtattt actctaaaat tatactgtct
    15661 atctcttatt aatgtagcca ttatagtctc cttaattgcg ttatccttat gtataacaag
    15721 attataacaa atcaatagtg acttagcaat ataaagcaat ttgcaaactt gccattagtt
    15781 tactaaaaat aagtatgttt
//
LOCUS       DARYXS010000045        15774 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.046, whole genome shotgun sequence.
ACCESSION   DARYXS010000045 DARYXS010000000
VERSION     DARYXS010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15774
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.046"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..724
                     /locus_tag="TV193_001159"
     CDS             <1..724
                     /locus_tag="TV193_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1513359.1"
                     /translation="KEQPLYLQIVDVLEVKIRNTMSANDKLLSERELSDLFGVSRITI
                     RLALKELELRGLIYKQQGKGTYVSGIKEPATDLSSAYSFTEEMKKQGRKPQTVILSFE
                     KIKTTAYLSGMLDLDVDTDVFELERLRIADGKPLMFERTYIPERGFEAITIDLLEKKP
                     LYDVFAEDFQEAIRLADEEFYASIALDYEAKLLGIKKGDPVLHIMRKTYNEKNRLIEF
                     TFSIARADQFRYRIQHHPNKKI"
     gene            736..1911
                     /locus_tag="TV193_001160"
     CDS             736..1911
                     /locus_tag="TV193_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEL1513360.1"
                     /translation="MFTKTQAELELLGAAITTREIKQQPELWSEVFESFLKQKKDLLA
                     FFDRIIESANRNKVKIIFTGAGTSEYIGNTICHYLEMTGDRENYLYYSIASTDLVAAP
                     SQYLFEEDTVVLVSFARSGNSPESVAAVSLVNQLVSNPYHLVITCAKEGALAQNAKKD
                     KRSYLFLLPEASNDAGFAMTGSFSCMMLAALLIFDQAHSLEEKKCYLDQIVGMVAAII
                     QQEADLQKLVSLEFQRLVYLGSGALAGLTQEAQLKILELTAGKIATVYDSSMGFRHGP
                     KSFIDDQTLVIGFVSNDPYTRRYDLDVLEEIREDAIAVDTVALQQQGGEGFSGHCFGL
                     DSSMLLPDAYLAFPLVFIAQTLALLSSIKVNNLPDTPSATGTVNRVVQGVKIYHYFK"
     gene            1921..2916
                     /gene="lacD"
                     /locus_tag="TV193_001161"
     CDS             1921..2916
                     /gene="lacD"
                     /locus_tag="TV193_001161"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL1513361.1"
                     /translation="MYHLSKAKYRLLEKVSRKGIISALAFDQRGVLKRMMAAHQDTEP
                     TPWQIEALKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTS
                     RLPDCLVDWSVKRLKEAGADAVKFLLYYDVDGDERINQQKQAYIERIGSECQAEEIPF
                     FLELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSTERFGVDVLKVEVPVNMAYVEGF
                     AEGEVVYSKEEAMQAFRDQEAASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLC
                     GRATWSGAVAVYMSEGEEAARQWLRTEGFENIDRLNQVLEKTASPWTTKLTLDEA"
     gene            complement(2958..3677)
                     /locus_tag="TV193_001162"
     CDS             complement(2958..3677)
                     /locus_tag="TV193_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1513362.1"
                     /translation="MTIKYPKYRLIKEELQNQILNGHYHTGDKFYTEAELIKRFHVSS
                     ITIIRALKELEKEGFIRRRQGLGTFITRTRKEQLVQFSYLGTFKDQKEEVTVLSVVKG
                     NDPYYLNLLKLHKTEFYYTISRTRTINQQPYLYQLSYIPHDYLLCPERDLADYQSLYK
                     RFFLDFHIQMRSQSFTQQTQLTDHMPKDVATFLNMIDNTPCVLQTKLTRSTDNGRILE
                     YTESYKHWQFFKYALSSSDYQ"
     gene            3817..5636
                     /locus_tag="TV193_001163"
                     /pseudo
     CDS             3817..5636
                     /locus_tag="TV193_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622686.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
     gene            5654..6139
                     /locus_tag="TV193_001164"
     CDS             5654..6139
                     /locus_tag="TV193_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1513363.1"
                     /translation="MTIVAARIDGRLIHGQVANLWTTKLNISRIMVVDNEVISNDLEK
                     TALKLATPSGVKLSILSVEKAANNILEGRYDSQRLLIVARKPDSFLELIQKGVAISEL
                     NVGNMSQTPETRPVTRSINVVDEDIEAFKAISAKGCHLIAQMVPNDAPADFMPLLDKV
                     D"
     gene            6185..7066
                     /locus_tag="TV193_001165"
     CDS             6185..7066
                     /locus_tag="TV193_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1513364.1"
                     /translation="MIQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGD
                     VQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAISTIAVPV
                     AALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVS
                     LGGGAVDTVVKFIDHYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLT
                     AMLTTIYTNLQVAGGALAGVAKDFNAAPFKGLPMIGIAIIGLSLATLHYKNGQQAPVA
                     EQKPGVSESGEIEDDEI"
     gene            7053..7871
                     /locus_tag="TV193_001166"
     CDS             7053..7871
                     /locus_tag="TV193_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEL1513365.1"
                     /translation="MTKSNYKLTKQDFNQINKRSLFTFQWGWNYERMQGSSYLYMILP
                     QLRKIYGDGTPELKEMMKTHTQFFNTSNFFHTIITGIDLALEENEGLASKDAVNGIKT
                     GLMGPFAPIGDSVFGSLVPAIMGSIAAGLAKEGVWSGITGVLMWVCTQMIINVFRWKQ
                     LEIAYKEGTKLVTTMRDKLTAVVDAASVMGVFMVGALIATMINFQFTAAPKIGEKVIN
                     IQDLIDTIFPRLVPALFTGGIFWLLGRKGMSPTKAIVVIILFALVMSYFNILGV"
     gene            7875..8279
                     /locus_tag="TV193_001167"
     CDS             7875..8279
                     /locus_tag="TV193_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEL1513366.1"
                     /translation="MAQTLILISHGAFCRELKQSTEMIMGPQDNILTAELQPNEGADD
                     FKEKLLRLIAGLDDVLVFADLMGGTPCNVASRLLMEGHQFELYAGMNMPMVIGFINAC
                     LIGEAFDFKAFACDNIHHVNTIISALADDDDD"
     gene            complement(8383..8643)
                     /locus_tag="TV193_001168"
     CDS             complement(8383..8643)
                     /locus_tag="TV193_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEL1513367.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYKFLSGSTKTSKETIEFEGETYPL
                     VRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(8768..9700)
                     /locus_tag="TV193_001169"
     CDS             complement(8768..9700)
                     /locus_tag="TV193_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEL1513368.1"
                     /translation="MTTFQTILEHIKHYQTIIIHRHQNPDPDALGSQAGLKEIIRHNF
                     PDKKVLITGFDEPSLAWISLMDQVSDDDYKEALVIVTDTANRPRIDDERYTMGACLIK
                     IDHHPNDDVYGDLSYVDTKTSSASEIIAEFAFSQGLALTDEAARLLYTGIVGDTGRFL
                     YASTSSKTLAIASQLRNYAFDFAAISRQMDSFPLKIAKLQGYVFEQLDIDDSGAARLL
                     LSQEVLNSFGISLAESSAIVSAPGKIDVVQAWVIFVELPDGQYRVRMRSKEKVINGIA
                     KRHQGGGHPLASGATSSGLEENEQIYQELIDLLT"
     gene            complement(9710..10138)
                     /locus_tag="TV193_001170"
     CDS             complement(9710..10138)
                     /locus_tag="TV193_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1513369.1"
                     /translation="MWVVKAFDQLTKDELFAIYKERVAVFVVEQQCPYPDIDDLDQKA
                     IHLFKQVDSELRAYCRLIPTDNSIKLGRVLVAQNARRTGLGRDLVHQALAYCQQHFPK
                     LPVYAQAQAYLEPFYSSFGFKAVSEIYLEDNIPHIDMIKN"
     gene            10396..11421
                     /locus_tag="TV193_001171"
     CDS             10396..11421
                     /locus_tag="TV193_001171"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEL1513370.1"
                     /translation="METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSE
                     LKQLVTAPETCESLMDYLKTFDVIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFA
                     PELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
                     ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIK
                     RLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSI
                     NTDNRTVSDTNLTKEYELFVKHFETSVTDFLEHNRDAIKASFASPAEKEALLDRLEKA
                     YQSYIKK"
     gene            11482..11928
                     /locus_tag="TV193_001172"
     CDS             11482..11928
                     /locus_tag="TV193_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEL1513371.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVEVDECTTVDAS
                     ELEAADMAIVATYTYGDGDLPDEIVDFYEDLQDLDLSGKIYGVVGSGDTFYDYFCKSV
                     DDFDEQLAATGATKGADSVKVDLAAEEEDIARLESFAEQMSQALEA"
     gene            12257..12550
                     /locus_tag="TV193_001173"
     CDS             12257..12550
                     /locus_tag="TV193_001173"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEL1513372.1"
                     /translation="MGLETIRQDINAVDRQLIALLEKRMVLADQVAAYKQVHDVPVLD
                     QEREAEVLRSVSQQIRHKAFEPAILELFKTIMAVSRRYQAEQIAVGSNDDEAY"
     gene            12531..13763
                     /locus_tag="TV193_001174"
     CDS             12531..13763
                     /locus_tag="TV193_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL1513373.1"
                     /translation="MMMKPIKNNQDISIGDNVYLAFAALLVGVVVGVIDTVFGQGLLL
                     LSAVRDAHLIYLLPCLALAGLVIVFLYEQYGQIAKQGMGLVFDVGHGEKTRLPLVLIP
                     LIILSTWLTHLCGGSAGREGVAVQIGATVSHFFGRLRHLKDKSQLFLVMGMAAGFAGL
                     FQTPMTAVVFALEVLLLGNISYLALLPSLIAAFTASWTSHCLGLEKFSVPIAKALKIT
                     PITFGKLVLLGLIFGLAGNLFASLLARAKPYIAARLPNPYYRVLLVGGFLSLSLLLCH
                     YGRYSGLGTNLITAAFSHQPIANYDWLLKLLFTIITLSAGFQGGEVTPLFAIGAALGI
                     VLAPWLGLPAQLAAALGYAAVFGSATNTFLAPIFVGLEVFGATNATAYFIVIAFAYMV
                     SRRHSIYTKQRVTTSIAS"
     gene            13909..14256
                     /gene="rplS"
                     /locus_tag="TV193_001175"
     CDS             13909..14256
                     /gene="rplS"
                     /locus_tag="TV193_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEL1513374.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFE
                     GVVISRKSQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            14771..14842
                     /locus_tag="TV193_001176"
     tRNA            14771..14842
                     /locus_tag="TV193_001176"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14804..14806,aa:Arg,seq:cct)
     gene            complement(14966..15769)
                     /locus_tag="TV193_001177"
     CDS             complement(14966..15769)
                     /locus_tag="TV193_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1513375.1"
                     /translation="MSKSRRRNWKSLTIVLLTILTIFTANSVQSARKLRTFPDTTEIS
                     LGTKATEIPGILPFTGKYQIALGDLDHLQRATYAHIQLKDQDEPTLKRKALRFNPPGW
                     HNYQVINSRGKKTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDNWLAIHPNFWLDYKVTPIYQNDELVPRQVVLQYVGIDQNGELLQIKLGGNKES
                     VDHYGITSVVLDNVSPLAALDYRTGMLLDENQHTEEGNNLATEELDEAA"
BASE COUNT         4380 a         2976 c         3699 g         4719 t
ORIGIN      
        1 aaaggaacag ccactctact tacaaattgt tgatgtatta gaggtcaaaa ttagaaatac
       61 catgtcagct aatgataaat tgttatcaga acgagagcta agtgacttat ttggtgttag
      121 tcggataacc attagattgg cacttaagga gctagagctg cgtgggctta tttacaaaca
      181 gcagggcaag gggacctatg tatcaggcat aaaggagcct gctacagacc tgtcctcagc
      241 ctatagcttt accgaagaga tgaaaaagca aggtcgtaag cctcaaacag tcattctttc
      301 atttgaaaaa atcaagacca cagcttactt gtctggtatg ttagatttag atgttgatac
      361 tgatgttttt gagctagagc gtctaaggat tgcagatgga aagccattaa tgtttgagcg
      421 cacttatata cctgaaaggg gatttgaggc gataacgatt gatttattgg aaaaaaagcc
      481 cttatatgat gtgtttgctg aggattttca ggaagctatc cgattggctg atgaggagtt
      541 ttacgctagt atcgctctag attatgaagc aaagctatta gggatcaaaa agggggatcc
      601 tgtgctgcat attatgcgta agacctataa tgagaaaaat aggctaatcg aatttacctt
      661 tagtattgct agagcagacc agtttaggta ccgtatccag caccacccta acaagaagat
      721 ataggaggta aggaaatgtt tacaaaaaca caagcagaac tagagctact tggcgcagct
      781 atcaccacta gagaaatcaa gcagcagcca gagctatggt cagaggtctt tgagtctttt
      841 ctgaagcaaa aaaaagacct cttagccttt tttgacagga ttattgaaag cgctaacaga
      901 aacaaggtaa aaattatttt tacaggagct ggaacttctg aatacattgg caataccatt
      961 tgtcattatt tggagatgac tggtgacagg gaaaattatt tatattacag cattgcttcc
     1021 acagaccttg ttgcagctcc aagccagtat ctctttgaag aggatacagt cgtgcttgtt
     1081 tcctttgcaa gaagtggcaa tagtcctgaa agtgtcgctg ctgttagtct tgttaatcag
     1141 ctggtgtcaa atccttatca tttggtgata acctgtgcca aagagggggc cttagctcaa
     1201 aatgctaaga aggacaaaag gagctattta ttcttgctgc ctgaggcctc aaatgacgct
     1261 ggctttgcta tgacgggaag ctttagctgc atgatgctag cggccttgtt gatttttgat
     1321 caagcgcatt cccttgagga gaaaaaatgc tatttagatc agattgtagg tatggtggca
     1381 gctattattc agcaggaggc tgatttacaa aagctggtta gcttagagtt tcaacgcttg
     1441 gtttacctgg gatcaggagc cttagcgggg cttacgcaag aggctcaatt gaagatttta
     1501 gaattaacag ctggcaaaat tgcaacagtc tatgactcct caatgggctt taggcatggt
     1561 ccaaagtcat ttattgatga tcagacattg gttattggtt ttgttagcaa tgatccttat
     1621 acgagaaggt atgaccttga tgttttagaa gagataagag aggatgctat tgctgttgat
     1681 acggttgcat tacagcagca aggaggtgag ggctttagtg ggcattgctt tggcttagac
     1741 tcgtcaatgc tattgccaga tgcttatttg gcctttccgc ttgtttttat cgcccaaacg
     1801 cttgctttgc tgtcgtctat taaggttaat aatttaccag atactccttc ggccacagga
     1861 acggttaaca gggttgtcca aggtgttaag atttatcact attttaagta ggagaacaag
     1921 atgtaccatt tatcaaaagc taagtatcgt cttcttgaaa aggtcagtcg taagggcatc
     1981 atttcggcct tggcctttga tcaacgcggg gttttaaagc gcatgatggc agcccaccaa
     2041 gacacagagc caactccttg gcaaatcgaa gccctaaagg ctctggtatc agaggagcta
     2101 accccctatg cctcctctat cctgctagac cctgaatatg gcctgccagc caccaaggtg
     2161 cgtgatgaga agtctggctt attattagcc tatgaacaaa ccggctatga cacaaccacc
     2221 actagccgcc tgccagattg tctggtggac tggtcagtca agcgcctcaa ggaggccgga
     2281 gctgacgcag tgaagttctt gctgtactat gatgttgatg gtgatgagcg tattaaccaa
     2341 caaaagcagg cctatatcga gcgtatcggc tcagaatgtc aggcagagga gataccattt
     2401 ttccttgagc tattgaccta tgatgaggcg ataacagaca atcagagtgt agcttttgcc
     2461 aagctaaagg cacacaaggt taatgaggcc atgaaggtct tttcaactga gcgctttggg
     2521 gttgatgtcc taaaggtaga ggttcctgtc aatatggcct atgttgaggg ctttgcagag
     2581 ggtgaggttg tttacagcaa agaggaggct atgcaggcct ttcgtgacca agaggcagct
     2641 agtcacttgc cctatattta tttgagtgcg ggtgtatcag ctagtctgtt tcaagagacc
     2701 ttggtttttg cggcagaggc aggagctagg ttcaatggtg tgctgtgtgg tagggccact
     2761 tggtcaggag cagtagcggt gtacatgtca gagggcgagg aggcagcgcg tcaatggctt
     2821 cgcacagagg gttttgaaaa tattgatcgt ctcaatcagg tgcttgagaa aacagccagc
     2881 ccttggacaa caaagcttac tcttgatgaa gcctagtaaa ggcatgataa aagcaatact
     2941 aggacattgc ttctgtatta ttggtaatca ctggaggaca aggcgtactt gaaaaattgc
     3001 caatgcttgt aggactcggt gtactctaga atacggccat tatctgtcga ccgagtgagc
     3061 ttggtttgaa ggacacaagg agtgttgtct atcatgttta aaaatgtagc gacatcttta
     3121 ggcatgtgat ccgtcagctg tgtttgctgg gtgaagcttt gtgatcgcat ttgaatgtga
     3181 aaatccaaaa agaagcgctt ataaagcgac tggtaatcag ctaaatcacg ctcagggcac
     3241 agcaggtaat catgaggaat ataagatagc tggtataaat agggctgctg attaatcgtt
     3301 cgtgtacggg agatggtgta gtaaaattcc gttttatgaa gtttcaagag atttagatag
     3361 tagggatcat ttcccttaac tacactaagg acagtcacct cctctttttg atccttaaag
     3421 gtacctagat aggaaaattg gactagctgt tcttttctgg tacgggtaat gaaggttcca
     3481 agtccctgcc ttcttctgat aaagccttct ttttctagtt ctttaagggc tcgaatgatg
     3541 gttatggagc taacatgaaa gcgtttaatc agctcggctt cggtataaaa tttgtccccg
     3601 gtatggtagt ggccattcag aatttggttt tgcaattctt ctttgattag tcggtacttt
     3661 gggtatttga tggtcatagt tactcactca ataattgttt agtacgatta tagcaaaaat
     3721 agtaagctga tgtcatatct taccagttat tgctcagata gcttgtcaat cagtcattga
     3781 tcaaaggctg atggttaatg aataaaagga gataatatga agcaattttg cataaaggag
     3841 cagttttacc ttgatggcaa gccgtttaag atattatcag gtgccattca ttactttaga
     3901 atagctcctg atagctggtc tagggtgctt tatcagctga aggccttagg ctttaataca
     3961 gtagaaacct atattccttg gaatatgcat gagccaagga agggacagtt tacctttgag
     4021 gggattgcag atgttgaggc atttttggat ttggcacagg aatgtggcct atatgctatt
     4081 gtcagaccct ctccttatat ctgtgctgaa tgggagtttg gtggtttacc ggcttggcta
     4141 ttaactgaaa attgtaggct cagatcaagc gatgaggtct ttcttaagca tgtatcagat
     4201 tattatgatg tgttactacc aaagctggtg aagcgtcagt tagataatgg cggcaatatt
     4261 ctgatgtttc agcttgaaaa tgagtatggt tcttatggtg aagaaaaggc ttatttaaga
     4321 aaattaaaag agcttatgct tgctaaaggc attagtgccc ctctctttac ctcagatggg
     4381 ccttggccag ccacgctagc atcagggagt ctgattgacg atgatgtttt tgtgacaggc
     4441 aactttgggt caaacgcttc aaagcaattt gccagtatgc aggatttttt ccaagcacat
     4501 caaaagcaat ggcctctgat gtgtatggaa ttctggttgg gctggtttaa tcgctggaat
     4561 gagccaatca ttcgaaggga ctccaaggaa gctgttgatg caatcatgga agctatagag
     4621 ctaggcagca ttaaccttta tatgttttgt ggtggcacta attttggctt tatgaatggc
     4681 tcgtcagctc gtctgcaaaa ggatttacca cagataacct cctatgatta cgacgcatta
     4741 ctagatgagg cagggaaccc gacaaagaaa tataccctgc tgcaagaatg tactgacccc
     4801 caaaagttag acataaaatc taacaattgg ggggcagttc agaacgtctc aaggagtgtt
     4861 accctcaatt atcctttgca gagccaatga tcagttctac gatggcctta gagtctatca
     4921 agttgtcggc aagggttagt ctttttaaga caatcaaaaa tgtaagcgct atcaagaaaa
     4981 gtttttatcc ttgtaatatg gaggagctag atcaaccaac gggctaccta ctgtatagaa
     5041 cgcacctcgc tagacatagc aaggaggagc ggctcagggt cattgatgct agagaccgca
     5101 ttcagctctt tttagatgaa aagcacgtga aaacccagta tcaggaggaa atcggtcagg
     5161 atatactgat acatcaagag ggtgagacca cacagcttga tattttagtc gaaaatatgg
     5221 gacgtgtcag ctatgggtac aagctgacag caccaagcca acaaaaagga ttaggcagag
     5281 gcttaatggc tgacttgcat tttgtaggtg attgggagca ttttccacta gattttcaag
     5341 agctggattg gattgatttt tctgcaggtt ggaccgatga ggtgccagga ttttacgcct
     5401 atgattttga ttgtcagcag ccggcagata cctaccttga tttgagtcaa ttcggaaaag
     5461 gaattgccct tgtaaatggt gttaacctag gacgtttttg gaaggtcggt ccaacattat
     5521 cgctttatat tcctaaggga ctattaaaac aaggtcaaaa tagactgctg atatttgaaa
     5581 cagaagggca gtttagtgag tcaattcgtt taactaagga accaatttat aaatagataa
     5641 aaggagaaaa cttatgacaa ttgttgcagc acgtattgac ggccggttaa ttcatggtca
     5701 ggtagctaat ctatggacga caaagctaaa cattagccgt atcatggtgg tcgataatga
     5761 ggtgattagc aatgaccttg aaaaaacagc actgaagcta gccacaccta gcggtgttaa
     5821 attatctatc ttatctgttg aaaaagcagc caacaatatt ttggaagggc gctatgattc
     5881 tcaacgcttg ttgatagtag ccagaaagcc ggatagcttt ttggagctga ttcaaaaagg
     5941 ggttgctatt tcagagttaa atgtcggcaa tatgtcacag acaccggaga ctcgtccagt
     6001 aacgcgttct attaacgttg tagacgagga tatagaggca ttcaaggcta tttcagccaa
     6061 agggtgtcat ctcattgccc aaatggtgcc taatgatgcc ccagcagact ttatgccgct
     6121 gttggataag gttgattaag atgtgtcaaa tcaaaaacga atctgtttca ggaggtaaaa
     6181 gcttatgatt caatggtggc aaatcctatt attaacactc tactcagctt atcaaatatt
     6241 agatgagcta acaattgtct cttctgcagg ctcacctgta tttgcaggat ttatttcagg
     6301 tatcatcatg ggagatgtgc aaaccggtct ttggattggt ggtagccttc aattgatggt
     6361 gcttggtgtt gggacctttg gaggagcttc gcgtatcgat gcaacctctg gtgcggttat
     6421 tgcgacagcc ttctcggttg ctcaaggcat agagccagaa ttagcgattt caaccattgc
     6481 agttccggta gcggccttgc tggtttatac tgatattcta ggacgctttt caacgacctt
     6541 ctttgctcac cgtattgacc gccatgttga aaactttaac taccgaggca tcgagcgtga
     6601 ttaccttatg ggagctgtac cttgggccct atcacgtgct ctgccggtat ttttagcggt
     6661 ctctttaggt ggtggtgcgg ttgatacagt tgttaagttc attgaccatt atgaatggct
     6721 agcaaatggt ctaactcttg caggaaaaat gcttccaggc ttgggctttg cgatcttgct
     6781 tcactaccta ccagttaaac gtaatctcca ttatctggct ttaggttttg gcttgacagc
     6841 aatgctaaca accatttaca ccaaccttca ggtagctgga ggcgcccttg caggagtagc
     6901 caaggatttc aatgccgcac cattcaaggg gctgccaatg attggtattg ctattattgg
     6961 gctttccttg gcaaccctcc attataaaaa tggtcaacaa gcacctgtag ctgaacaaaa
     7021 acctggggta tcagaaagtg gggaaattga agatgacgaa atctaattat aaattaacca
     7081 aacaggattt taatcaaatc aataagcgca gcctgttcac attccaatgg ggctggaact
     7141 acgagcgtat gcagggctct agctatcttt acatgatttt accacagctt cgtaagattt
     7201 atggcgatgg aactccagag ctaaaagaaa tgatgaagac gcacacgcag ttttttaaca
     7261 catcaaattt ctttcatacg attatcacag gaattgactt ggcgttggag gaaaatgaag
     7321 gacttgcctc aaaagatgct gttaatggga ttaaaacagg cttaatgggg ccatttgctc
     7381 caattggtga ttcggtcttt ggctccttag taccagctat tatgggctct atagccgcag
     7441 gtcttgctaa agaaggggtt tggtcaggga ttactggtgt attgatgtgg gtatgtactc
     7501 agatgatcat caatgtgttt cgttggaagc agcttgaaat tgcttataaa gaaggtacaa
     7561 agctcgtcac caccatgcgt gataagctaa ctgctgtagt agatgcagcc tcagtcatgg
     7621 gagtattcat ggtaggggcc ttaattgcaa caatgattaa ttttcagttt accgcagcac
     7681 ccaaaattgg agagaaagtt atcaatattc aagatttaat tgataccatt tttccacgtc
     7741 tagttccagc cttatttacc ggaggtatct tctggctgct agggcgtaag ggcatgtcac
     7801 caactaaggc aattgttgtg attattttat ttgccttagt gatgtcttat ttcaatattt
     7861 taggagtata gctgatggcg caaaccttaa ttctcattag tcatggagct ttttgtcgag
     7921 agctaaaaca gagtacagaa atgattatgg ggccacagga caatatttta acagcagagc
     7981 tgcaaccaaa cgaaggtgcc gatgacttta aagaaaagct tttaaggcta attgcaggtt
     8041 tagatgacgt ccttgtgttt gcagatttga tgggtggaac accctgtaac gttgccagtc
     8101 gtttgttaat ggaaggacat cagtttgagc tgtacgcagg catgaatatg ccaatggtca
     8161 ttggtttcat taatgcctgt ttgatcggtg aagcgtttga tttcaaagcc tttgcctgtg
     8221 acaatattca ccatgtcaat accattattt cagctctagc agatgatgat gacgactaac
     8281 caagctcgct tatttgtcac gcaccttacg gagcgaaacg gaccaagagc cgcataatca
     8341 aaaaagacac tgccaaatct tggcagtgtc tttgctgtaa gcttattttg ctgcgtttgc
     8401 gtctttgaga ccgtatttct tgttgaaacg atccacacgt ccatcggctt gtgtaaactt
     8461 ttgacgacct gtgtagaatg ggtgtgagtc tgatgaaatt tctacacgaa caagagggta
     8521 agtttcccct tcaaactcaa tggtttcttt agaggtctta gttgaaccgc taaggaattt
     8581 gtagcctgta gttgtatcaa ggaaaacaac tggacgataa tctggatgaa tgtcttttct
     8641 catcttaaaa aagttccttt ctgccatgat actgtccgta tcatagttat taactactct
     8701 agtttaacaa aagttagtaa gcttgacaag ctttttctat cactattcat caataagatg
     8761 ataagtctta tgttaagaga tcaatcagct cttggtagat ttgctcattt tcctctaagc
     8821 ctgatgacgt ggcaccgcta gcaagagggt gcccgcctcc ttgatgacgc ttagcaatac
     8881 cattgatgac cttttcttta ctgcgcatgc gtactcggta ctggccatct ggcagctcaa
     8941 caaagataac ccaagcctgc accacgtcta tttttccagg agcagagaca atcgctgagc
     9001 tttctgccaa gctaatacca aaggaattta ggacctcctg gctaagcagt aggcgggctg
     9061 caccactgtc atctatatca agctgctcaa aaacatagcc ttgtagcttg gcaattttaa
     9121 gtggaaagga atccatctgc ctcgaaatag cagcaaagtc aaaggcataa tttcttaatt
     9181 ggcttgcaat ggccagtgtt ttactgcttg ttgaggcata gagaaagcgt cctgtatctc
     9241 ccacaatgcc agtatataat agtctagctg cctcatcagt taaagccaag ccttggctaa
     9301 aggcaaattc agcaataatc tcactagcac ttgaggtctt ggtgtcaacg taggagagat
     9361 caccatagac atcatcgtta gggtgatgat caattttaat gaggcaagcg cccattgtgt
     9421 agcgctcatc atcaatgcgg gggcgattgg cagtgtctgt aacaatcact aaagcttcct
     9481 tataatcatc gtcggacacc tgatccatga gactaatcca agccagacta ggctcatcaa
     9541 agcctgttat caggaccttt ttgtcaggga aattatgcct gataatctct ttaagtcctg
     9601 cttggctccc tagagcatct ggatcggggt tttggtgccg atgaatgatg atggtttgat
     9661 agtgcttaat gtgttctaaa atagtttgaa acgttgtcat aggtatcctt tagtttttga
     9721 tcatatcaat gtgaggaata ttgtcttcca gataaatctc agagactgct ttaaacccaa
     9781 atgagctgta aaaaggctca agataagcct gcgcttgagc gtagacggga agctttggaa
     9841 agtgctgttg acaataggct aaggcttgat gaactaagtc acgtcctagt cctgttcgcc
     9901 ttgcattttg tgctaccagt actcgtccca gctttatgct attgtcagtt gggattaagc
     9961 gacagtaggc cctaagctct gaatcaacct gcttgaaaag atggatagct ttttgatcca
    10021 aatcgtcaat atcaggatag ggacattgct gctcaaccac aaaaacagcc acacgctctt
    10081 tatagatggc aaacaattca tcttttgtta actgatcaaa tgctttaaca acccacatta
    10141 gctagcctcc aaaatcactg gtacaatttc ctttatgata acataatagc atatatcagc
    10201 cataatggaa cgaaaaaaac ctgactctta atggacgatg tcgtgatgat aattacatct
    10261 tgtctcaaaa gctggtaatc atcacaggca cagaaaaatg tgccccttct gttgcttttt
    10321 gagaaaaagt tcacttgctt tttggtagtt ttttggtatc atactaaaaa atagacttaa
    10381 ttaaggagat acagcttgga aacaaaagat ttaaagaagc ttgctaaagc tgagctgcac
    10441 tgccatttag acggttcttt gtcattagac actattcgtc agttggcggc tttggcgcag
    10501 gtagatgttc ctcaagatga ttctgagtta aagcagctgg taaccgcacc ggaaacctgt
    10561 gaatccttga tggattattt aaaaaccttt gatgttatca gaccattatt acaaacgcct
    10621 caggctttaa cattggctgc ttatgatgtt gtgaagcagg ctgcccttga aaatgtcatc
    10681 tacattgaaa ttcgatttgc tcctgagttg tcaatggatc agggcttgac cgccactcag
    10741 gtggtagagg cagttttaaa aggactcgag caaggacaaa aagagtttgg cattgtcgct
    10801 aaggctattg tgtgtggcat gcgtcagtcc tcactagaca ttagcagaga gatttttgca
    10861 aatgtcttag agtgggccaa taaaggcttg gtaggctttg attttgcagg caacgagctg
    10921 gactttcctc cagctgtctt agcagatttg atcaaagaga cgcaggccta tgggttacca
    10981 tttacgcttc atgctggtga gtgtggctgt ccaaactata ttgttgatgc tattgattta
    11041 ggtatcaaac gcttagggca tgtgacggcc attcataacc aaaaggattt attggccaag
    11101 tttatcgcca atgatgtgac agcagagctg tgcttcacta gtaatctaca aaccaaggct
    11161 gctaggactg ttgaggactt tccttatatg cagctaaggc aggctggcgc taaattatcc
    11221 attaacacag acaatcgaac agtatccgat accaatctga caaaggaata tgaactgttt
    11281 gtcaagcact ttgagacaag cgtcacagac tttttagagc ataatcgtga tgctattaag
    11341 gctagttttg ccagtccggc tgaaaaagaa gctttattgg atcgtttgga aaaggcttat
    11401 cagtcttaca tcaagaaata atgcttttct tggcaaagta tgataaaata tactgacatt
    11461 tagttatttt gggaggaaat tatggcatta gccaaaatcg tttatgccag catgacagga
    11521 aatactgaag aaattgctga tattgttgct aataaattgc aagaattggg acatgatgtt
    11581 gaggttgacg agtgtacaac agttgatgct tcagagcttg aggctgctga tatggcaatc
    11641 gttgcgacct atacctatgg tgatggggac ttaccagatg agattgtcga cttttatgag
    11701 gacttgcagg atttggattt gtcaggcaag atctacggtg tcgtgggctc tggtgatacc
    11761 ttttatgatt atttctgcaa atcagttgat gattttgacg aacagctcgc tgccactggt
    11821 gccactaagg gagctgactc ggttaaggtt gatttagctg ctgaggaaga ggatattgct
    11881 cgcctagaat cctttgctga gcaaatgtca caggcattag aggcataagt aagacttttg
    11941 atacagattg gtaaaacggt cagtggaggc ttgcgttttt taccaccaaa tgcatgaaaa
    12001 actgatattt tctgatcgtt ttttcatgac tatgtgctct ttttcaagaa aagtcatgcc
    12061 attattagcc tgaatgcaaa caattgatag tgtcaaaatg ttgatcatat agtaaaaaaa
    12121 tgcatgtgac tagaaagcag ttacatgcat tttcgtcatg cgtttgtcgt gaggcatttt
    12181 gggggttact tgcttactga gctgaaattc actataataa aaagataaat aaagaaaaga
    12241 agaagttagg tgaatgatgg gattagagac catacgacaa gacattaatg ctgttgatcg
    12301 tcagttgatt gctttgctgg aaaagagaat ggtcttggct gaccaagtag cggcctataa
    12361 gcaggtacat gatgtgccag tgcttgatca agagcgagag gctgaggtcc taaggagcgt
    12421 gtcacagcag attcggcata aggcctttga gcctgccatt cttgagctat ttaagacaat
    12481 tatggcagta tcaaggcgtt atcaggctga gcaaatagcg gttggttcaa atgatgatga
    12541 agcctattaa aaacaatcaa gacatcagta taggtgataa tgtctatttg gcttttgcag
    12601 ccctgctcgt tggggtggtg gtaggtgtga tagatactgt ttttggacaa ggcttgttgc
    12661 tcttgtctgc tgttcgtgat gctcatctca tttacctgtt accctgctta gctcttgctg
    12721 gacttgtgat tgtgttctta tatgagcaat atggccaaat cgctaagcag gggatgggct
    12781 tagtttttga tgtggggcat ggtgaaaaaa caagactacc actggtgttg attccgttga
    12841 ttatcctctc aacctggctg acgcatttat gtggaggcag tgctggtcgt gaaggcgtag
    12901 cggttcaaat tggagcgaca gtgtcacatt tttttggacg tcttagacat cttaaggaca
    12961 agtcacagct gtttttagtc atgggaatgg ccgcaggctt tgcgggctta tttcaaacgc
    13021 caatgacagc ggttgttttt gccttagagg tcctgttgct aggaaatata agctatttag
    13081 ccttgctacc ttctcttata gcagccttta ccgcctcttg gacctctcat tgcctaggct
    13141 tagaaaaatt ttcagtcccg atagccaagg ccttgaaaat caccccgata acctttggga
    13201 aattagtgct actaggcctt atttttggct tggctggtaa tctttttgcc tccttgttag
    13261 caagggctaa gccatacatt gcagcaaggc tgccaaatcc ttattatcgt gtgttgcttg
    13321 ttggtggttt tctatcgctt agcctgctgc tgtgccatta cgggcgctat agtggcctag
    13381 ggactaactt aattacagcg gcctttagtc atcagcctat tgctaattat gattggctat
    13441 taaagctctt gtttaccatt atcactctct cggctggctt tcagggcggt gaggtcactc
    13501 cactttttgc tattggtgcg gctttaggaa ttgtcctagc accatggctt ggcttgccgg
    13561 ctcagttggc tgcagccctt ggctatgctg cggtatttgg cagtgccacc aatacctttt
    13621 tagccccgat atttgttgga ttagaggttt ttggtgcaac aaacgcaact gcttacttta
    13681 tcgtgatagc ctttgcttat atggtgagcc gaaggcattc aatctacact aagcaaaggg
    13741 tgaccactag catcgcttcc tagtgtcttg gtcagttttt tggagaaaat agctttacaa
    13801 gtggggctta ttttgttaca ataggctccg tgtgtaatgg acgcacaaaa attacggcta
    13861 atccgctaag actcgcgctt aagattagta agataaggag aataaacaat gaatccatta
    13921 attcaaagct tgacagaggg tcaacttcgt actgatattc ctagcttccg tcctggtgac
    13981 actgttcgtg tgcacgcaaa ggttgtcgaa ggatctcgtg aacgtatcca gatctttgag
    14041 ggagtagtca tttcacgtaa aagtcaaggt atctcagaga tgtatactgt tcgtaagatt
    14101 tctagtggta tcggtgtaga gcgtaccttc ccaattcaca caccacgtgt tgaaaagatt
    14161 gaggttgtgc gtcatggtaa ggttcgtcgt gctaagcttt actacctacg tgccttgcaa
    14221 ggtaaggcag cgcgtatcaa ggaaattcgt cgctaaaaag agcatacgag aggtttttca
    14281 ctgtcttatg aaaggactgc tggagcagca gggtctttgg gacaagcttt ttttcgcagg
    14341 tatgtgaacc tacgctcaat tcaagacata tcaaaggctc attctatgat agagtgggct
    14401 ttttgattgt gatcatgctt tagtgcctaa ataaatgaca gcagcctgac taatgaaagg
    14461 cttacttgac tttggaaatg ctcaaggctt gcgctaccag atagaagctg acatcatgcc
    14521 atagcagtca aggggaagaa ggactagatt ttttggcgag gtgttgatct gtgaccctga
    14581 tgttgttggg aatatgagag taatttaaaa tttcgtcttg cattctacct ttttctaggt
    14641 tacaatagac aagtaacctg attagtgaag ctaaaagacg tagcgatggg ttctaaaaaa
    14701 gaatgattct ggcgtttttg gctaacctaa gctgatagct ttgctaggca gtgtcttagt
    14761 catctggtca gtcctgctag tttaacggat aaaacaagcg cctcctaagc gctagctgtg
    14821 ggttcgattc ccgcgcggga cattaaaaac aaagtaaaaa gagtctgaga aggtttgagc
    14881 tgcccctaat tgttagattt ttttctaact cttgaagtgt gggtcaaaga ctatttgtct
    14941 caggactctt tttaattggt ttttactaag ctgcttcatc tagttcttca gttgctaagt
    15001 tgtttccttc ttctgtatgt tggttttcat caagtagcat tcctgtgcgg taatctaatg
    15061 ctgccaaagg tgatacatta tccagaacaa ctgaggttat accataatga tcaacggatt
    15121 ctttgttgcc tcccaatttg atttggagga gctctccgtt ttgatcaatt ccaacgtact
    15181 gtaacactac ttgacgagga actaattcat cattctgata aataggagtt accttataat
    15241 ctagccaaaa gttagggtgt atggctaacc aattgtctag tctattttca taataaagca
    15301 ttcctaaagg atttttatca ctaaaacctg tattaaggta ttttgtcata gtaactaaat
    15361 ttttgggttc atcatttagg ccgctaaact gataaccgac tagatgtccg cgatccatta
    15421 accaagtctt tttccctcta gaattaatga cttgatagtt atgccagccg ggaggattaa
    15481 atctaagcgc ttttcttttg agagttggtt catcttgatc tttgagttgt atgtgtgcat
    15541 aggtggctct ttgtaaatga tcaagatctc ccagagctat ttggtatttt ccagtaaacg
    15601 gtaaaattcc tggtatttcg gtagcttttg ttcccaatga tatttccgtt gtatctggga
    15661 aggttctaag ttttcttgca gattgaacag agttagctgt gaaaatagtc agaatagtta
    15721 acaaaacaat tgttagactt ttccagttac ggcgacgtga tttagacata tcaa
//
LOCUS       DARYXS010000046        15116 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.047, whole genome shotgun sequence.
ACCESSION   DARYXS010000046 DARYXS010000000
VERSION     DARYXS010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15116
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.047"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(43..2631)
                     /gene="hylB"
                     /locus_tag="TV193_001178"
     CDS             complement(43..2631)
                     /gene="hylB"
                     /locus_tag="TV193_001178"
                     /EC_number="4.2.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEL1513376.1"
                     /translation="MATGTEKKHQEKLYIPKLKVNQIKLELFYEAGHGQVVFDNLSLR
                     EAGDKPSDDIKIASHYLEEQIVLPLNKHYLMEMADYHYQIAAESSNIVRVENGLLIPL
                     AQGKTLLEVLDQEGQRVATVPVEILAAEAPQTTSLITKWCEVILGAENFDRSSPAMVA
                     LNQKLDDSVTKNLADLTKDQKSTYLWSDLADLHQSSHMTATCRRLEEMAKQVSSLASR
                     YYQDKELIRLIKDKLAWLTLNYYHPQKDIEGKANWWDFEIGTPRAIVNTLAFIYPYVT
                     QEEIKRYTKGISHFVPNPRQFRLTLVNPFKAIGGNLVDMGRVKIIEALLKHDKKALQD
                     SIAALDTLFAFQPKGSRGEGFYEDGSYIDHTNVAYTGAYGNVLIDGLSQLVPLLQLLA
                     TSLDQQKLEVMTHWIEQAFLPLMVHGELMDMSRGRSISRENASSRQAALEALRGMLRL
                     AEALPEQAKIRIKGKIKAVLAFHNQETILESLSSYYDMKLFKELLEDTTIQASPVKSY
                     LSLFNQMDKLAYYNAEKDFAFALSMHSNKTLNFEAMNDENTRGWYTGDGMFYLYNSDL
                     GHYSDHFWPTVNPLKMAGTTEAEVRREDVTVAYLKKLTNDYKEKAKEKAGMSTLPSSF
                     VGAIKAGDKTALAVMDFQNWDRTVSAKKSWTILDDQIVFLGTAITSQTHQAVTTTIDQ
                     RKENPDNSYTLFINGQETALTEEILYRDDVTSLLLLSKDGQANIGYLFAKPTALALSR
                     KVQSGCWSEINTNSNNKDLISQSFITISQTHSQASDSYAYTLLPNISKADFDKVCSEA
                     RIEVLRNDSKLQLIHDKKQGLLAVVKYNQAKEVVNGQLSLEKSGLYLYQKVGNDFKQL
                     SFKALS"
     gene            complement(2577..3230)
                     /locus_tag="TV193_001179"
     CDS             complement(2577..3230)
                     /locus_tag="TV193_001179"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513377.1"
                     /translation="MKQRKKLSSSVCSSIILACLFRAPTVLAEEKTAAKAISKELQRV
                     KKAPLKTEEASQESSPDTQDASSVATESSLGEQLILTGDNLLKNPQFDQTSPAQEHQS
                     TSLWSKESANDWKDYKDASKSQGCPKIAVSDNKLTMTSDGNQRFRGCVHQTVAINPDK
                     QYLLTFDIETKDKTGQAFARIIEEIKQGSGAAKEQRLWLRWQQELRKNTKKSFISLS"
     gene            complement(3270..3899)
                     /locus_tag="TV193_001180"
     CDS             complement(3270..3899)
                     /locus_tag="TV193_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1513378.1"
                     /translation="MRKSEIMLRLKANKLALVVRGASKKEAMACSLAGIEGGIKTIEV
                     AYTNPFASQVIAGLREAVGNDPEILIGAGTVLDDVTARLAILAGAQFIVSPSFSRQTS
                     RLCHRYAIAYIPGCMTIEEVVTALESGAEMVKVFPGATVGMSFIKAIKSPLPQVDVMV
                     TGGVTVTNVSDWFAAGAQVLGVGGEFNQLAAQGQFQAITARAADYMSSC"
     gene            complement(3901..4902)
                     /locus_tag="TV193_001181"
     CDS             complement(3901..4902)
                     /locus_tag="TV193_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1513379.1"
                     /translation="MTKVLLVGEPLIRISPSHFQTLGHACQAQLYYGGSEVNIARTLS
                     GFRAESSLLTALPDNQVGRSVEAFLKQSGVATEHVQWCGDRVGIYYLENGFGCRPSQV
                     AYDRSASSFSLLGPKDLDYGKLFEEVTHFHFSGITLALGKVSQDLVEQLAIEAMKRQV
                     CVSFDLNFRSSMISVREAKTLFSHFAQYADLIFGMEPLMCNQADHAMFDRAKAGQGAV
                     KERLAALYEAYHLKAIFHTERHIDDQGINHYLAYAYDGQLHRSIELSTPVLQRVGSGD
                     AFVAGCLYQLMRGQAIAAALDFAAATASLKCTVADDQLFVPVSQVDRVMKGNREVRR"
     gene            complement(4935..5576)
                     /locus_tag="TV193_001182"
     CDS             complement(4935..5576)
                     /locus_tag="TV193_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEL1513380.1"
                     /translation="MKIALINENSQAAKNSIIYETLVSVTNKHGYEVFNYGMYGKEGE
                     SQLTYVQNGLLASILLTSKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     AQINGGNALSIPFAKGFGWGAELNLTLMFERLFAEPMGGGYPKERAIPEQRNARILSE
                     LKAVTYRSLLEVLKEIDQDFLKETISGEHFQHYFFANAEPSDLVDYLREVLQQ"
     gene            complement(5611..6405)
                     /locus_tag="TV193_001183"
     CDS             complement(5611..6405)
                     /locus_tag="TV193_001183"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEL1513381.1"
                     /translation="MEHFFSLEGKIALITGASYGIGFEIAKAYAMAGAKIVFNDIKQD
                     LVDQGLAAYREFGIKAHGYVCDVTDEVGIQEMVAQIEKEVGIIDILVNNAGIIKRTPM
                     LEMTAKDFRQVVDIDLNAPFIVSKAVLPSMIKKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTPADLAGPAIFLASEASNFVNGHILYVDGGILAYIGKQP"
     gene            6714..7148
                     /locus_tag="TV193_001184"
     CDS             6714..7148
                     /locus_tag="TV193_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1513382.1"
                     /translation="MISIIVIGHGHFASGIVSSLELIAGKQEGITAIDFTAEMTAADV
                     HERLSVVLQSKTQALMLCDLLGGTPFKVAATLMEELSESTLDVLSGLNLAMLIEAVFA
                     RQEQLDLEQIVAKLLTTAKEGISNWKSLSGEAEEADLDEGGI"
     gene            7148..8347
                     /locus_tag="TV193_001185"
     CDS             7148..8347
                     /locus_tag="TV193_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL1513383.1"
                     /translation="MTRQIKEVTLEPLIQAEVYSQQPYLTKADIEAAILLALKQIRLN
                     MDYFGTDFPRPATKDNCYPIMDNTEWTNGFWTGCLWLAYEYTGNDTIKSLAQANDLSF
                     LERVTKDIELDHHDLGFLYSPSCMAEWKLLKTPEARQAALKAADKLIERYQEKGGFIQ
                     AWGQLGKAEDYRLIIDCLLNIQLLFFASQETGDDRYRQMAINHFYASANNVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKDPQLIALFKGM
                     THYFLNRLPKDQVSYWDLIFEDGSGQSKDSSATAIAVCGIHEMLKHLPENDPDKKAYQ
                     AAMHCMLRSLIDSYANKDIKPGAPLLRHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWTPYW"
     gene            8393..8881
                     /locus_tag="TV193_001186"
     CDS             8393..8881
                     /locus_tag="TV193_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEL1513384.1"
                     /translation="MTPPNIIMTRVDERLIHGQGQLWIKFLNCNTVIVANDAVAEDKI
                     QQSLMKPVVPSSIAMRFFSIQKVIDVIHKASPAQTIFIVVKDLEDIKRLVEGGVPIKE
                     VNLGNIHKTDDKIAITQFISLGDKDKAIIRTLTHDHHIVFNTKTTPAGNGASEVNILD
                     YI"
     gene            8896..9675
                     /locus_tag="TV193_001187"
     CDS             8896..9675
                     /locus_tag="TV193_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1513385.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFTYTAFAGAPETAKKQLQKGNIKGFTFAANGTIWAFAVIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEYYNKPKHATTAEQGGQQDDWI"
     gene            9662..10483
                     /locus_tag="TV193_001188"
     CDS             9662..10483
                     /locus_tag="TV193_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1513386.1"
                     /translation="MTGSNKLTKRDYLKTALRAFFLQNGFNYSNYQGIGYANVVYPAL
                     KKHFGNDKTGLYKALENNCAFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDTLTQFCLAPLFSTIAASLASDGLILGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKISVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKTKKWTTYKLVILTVIIGIVGSWLGVLA"
     gene            10883..11884
                     /locus_tag="TV193_001189"
     CDS             10883..11884
                     /locus_tag="TV193_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1513387.1"
                     /translation="MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAI
                     EATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMI
                     IDENQTSSQEIAQFLQGAFDKERHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFD
                     NIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQIFDCQVNWQESTF"
     gene            12474..12740
                     /locus_tag="TV193_001190"
     CDS             12474..12740
                     /locus_tag="TV193_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1513388.1"
                     /translation="MSDTITSSPVAASAAISELVGVDTSRVHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEATR"
     gene            12752..13111
                     /locus_tag="TV193_001191"
                     /pseudo
     CDS             12752..13111
                     /locus_tag="TV193_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13102..13983
                     /locus_tag="TV193_001192"
     CDS             13102..13983
                     /locus_tag="TV193_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513389.1"
                     /translation="MGVTYSAAESKALIQAMTNNIQIANEITDRLSSGCDHLIASLDS
                     GELQGAAYTAGRGLFTAIIIPSIKKLQAAIDAIQVELTTYQRADAQIARYGTLDRDHL
                     TELKRLRERQVQVIQAQIDENESFMKQVSSLLTGDYGTLWSDTSTLYHAKNQLEIGIR
                     DVTTKLESLEWFLTQTSDCFRDSLVILRLAIQGATQLSQVFMSSDGSYSTAGLDMSWV
                     TSLKNQKISPVNASKYTQNHYHNILTQTIKTIKSSSERPLQKSERLVAAYEDYLYFLN
                     KTAFDDYWKARSNYDGE"
     gene            14080..14508
                     /locus_tag="TV193_001193"
     CDS             14080..14508
                     /locus_tag="TV193_001193"
                     /inference="COORDINATES: protein motif:HMM:NF026945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513390.1"
                     /translation="MGDDILSVNVNAPYLSQVAGSQLSAAILDNKQFYDLVNTGQPLD
                     LKSRTYHGHNYSVWSRQWESELPGDYAGNYLYGYVGTGFLDASGTYLKTAAEIAQVFS
                     DKDIPKWLKNLSSGHYGDNEGDTQMIQAGIDGYMKRKKSK"
     gene            14505..15011
                     /locus_tag="TV193_001194"
     CDS             14505..15011
                     /locus_tag="TV193_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513391.1"
                     /translation="MKRKILLLMMLLVGVFIFSKRYELYYFFQGKEYLRPNESIELAV
                     RPKYEQIEYSSDLYLESDEKVLLKLEGRDIWSEYIYRRTDSYLSKIGYRYSITEQVIE
                     KYDSTKDNGVVIVEAGHKGATIDGDGLIVPLKGKRKYSVTEDHDYSITITNLSDQPVA
                     FRAIVADR"
BASE COUNT         4355 a         3363 c         3097 g         4301 t
ORIGIN      
        1 gctcaggggg gattttaact tattactaat gtgcttgaat ggctatgata aggccttaaa
       61 agatagctgc ttaaagtcat ttcccacctt ttgatagagg tataagcctg atttttcaag
      121 actcaattga ccattaacca cctccttagc ctgattgtat ttgaccaccg ccaacaggcc
      181 ttgtttctta tcatggatca gctgaagctt actgtcattt cgaagcacct caatacgtgc
      241 ttcgctgcac accttgtcaa agtctgcttt gctgatattt ggaagtaggg tgtaggcata
      301 gctatcacta gcctgagaat gagtttgact gattgtgata aagctttggg agatgaggtc
      361 tttattgtta ctatttgtat taatctcaga ccaacagcct gactgcacct ttcgcgatag
      421 cgctaatgcg gttggcttgg caaaaaggta accaatatta gcttgaccgt ctttagaaag
      481 tagtaaaaga ctggtcacat catctcgata caggatctcc tctgttagcg ctgtctcctg
      541 cccattgata aaaagagtgt agctgttgtc tgggttttct ttgcgttgat caatggtagt
      601 agtcactgcc tgatgtgtct gactagtgat ggcggtgcca agaaaaacaa tttggtcatc
      661 taagatcgtc caagacttct tggcactcac tgtcctatcc caattttgaa aatccataac
      721 agctaaagct gttttgtctc ccgccttgat cgctccaaca aaggacgatg gcagggtaga
      781 catgcctgct ttttctttgg ccttttcttt ataatcattg gttagctttt ttaaataggc
      841 tactgtcacg tcctctcgcc tgacctctgc ttccgttgtt ccagccatct ttaaaggatt
      901 aacagtcggc caaaagtggt ctgagtaatg acccaaatca ctgttataaa ggtaaaacat
      961 gccatctcct gtataccaac cacgtgtatt ttcatcgttc atggcttcaa aattcagagt
     1021 tttgttggaa tgcatggata aagcaaaggc aaaatccttt tccgcattgt agtaggccaa
     1081 tttatccatc tggttaaaaa gagataggta gctcttaact ggactggctt ggattgtggt
     1141 atcctccaag agctctttga atagcttcat gtcatagtag cttgataggc tctctaaaat
     1201 agtctcctga ttatggaagg ccaaaacagc cttgatctta cccttgatcc tgattttagc
     1261 ttgctctggc aatgcctcag ccagtcttag cattcctctt agtgcttcta aggctgcctg
     1321 ccttgaggag gcattttcac gactgatgga gcgcccacga ctcatatcca tgagctcccc
     1381 atgaaccatc aagggcaaga aggcttgctc aatccaatga gtcatgacct ctagcttttg
     1441 ctggtctagg ctagtagcta atagctgaag taatggtacc agctgagaca agccatcaat
     1501 aaggacattg ccataggctc cagtgtaggc gacattggta tggtcaatat aagagccatc
     1561 ttcataaaag ccctcacccc ttgatccctt tggctgaaaa gcaaataagg tatctagggc
     1621 tgctatactg tcttgaagcg ctttcttatc atgctttaac agagcttcaa taatcttcac
     1681 tcgtcccata tcaacaaggt tacccccaat ggccttaaaa ggattcacaa gggttaagcg
     1741 aaattgtcta ggattaggaa caaagtgaga aattccttta gtatagcgct tgatctcctc
     1801 ttgagtgaca taagggtaaa tgaaggctag ggtattgaca atagctcttg gggtaccaat
     1861 ttcaaaatcc caccaattag ccttgccttc aatatccttt tgcggatgat agtaattaag
     1921 tgtcagccag gctaatttat ccttgatcag tcttatcagc tccttatcct gataatacct
     1981 agaggctagg ctactcacct gcttggccat ttcctctaaa cgcctacagg tagctgtcat
     2041 atgagacgat tgatgaagat ccgccaaatc actccaaagg tatgtgcttt tctgatcctt
     2101 ggtcagatca gctagattct tggtcacgct gtcgtccagt ttttggttta atgccaccat
     2161 ggctggactt gatcggtcaa agttttctgc tcccaaaatc acctcacacc actttgtgat
     2221 caaggaggtt gtttgagggg cttctgctgc taaaatctca actggtaccg ttgctactct
     2281 ttgcccctct tgatccaaca cctctaaaag cgttttcccc tgcgccaaag gaattaaaag
     2341 accattttcc acgcgcacaa tgttgctgga ctccgctgca atctgataat gatagtcagc
     2401 catttccatg aggtagtgct tatttaaagg caggacgatt tgctcctcta agtaatgtga
     2461 agcaatcttg atgtcatcac ttggcttatc accagcctct ctcaaagaaa ggttatcaaa
     2521 gaccacctgt ccatgaccgg cctcataaaa gagctctagc ttgatttgat taacctttag
     2581 cttagggata taaagctttt cttggtgttt tttctcagtt cctgttgcca tcgaagccac
     2641 aagcgttgct cttttgcagc accagaacct tgctttattt cttcaatgat acgcgcaaaa
     2701 gcctgacctg ttttatcctt tgtctcaatg tcaaaggtca gcaaatactg cttgtctgga
     2761 ttgatggcaa cggtttggtg cacacagcct ctaaatctct gattgccatc gctagtcatt
     2821 gtcagcttgt tatcagagac agcaatttta ggacagccct gactcttact agcgtcctta
     2881 taatccttcc aatcatttgc agactccttg ctccaaaggc ttgtactttg atgctcttga
     2941 gcaggactgg tctgatcaaa ttgaggattt ttaagcaggt tatcacctgt gagaatgagc
     3001 tgctccccaa gactggattc cgtagctact gacgacgcgt cttgagtgtc tggggagctt
     3061 tcttgagaag cctcctcagt ttttagtggt gctttcttta ccctctgaag ctccttggaa
     3121 atggcttttg ctgctgtttt ttcttctgct aagactgttg gtgcccgaaa taaacaagct
     3181 agtatgatac tagagcaaac agaagatgat agtttttttc tttgcttcat ctgatacctc
     3241 cttgcttttt taatgtttta tgaccgactt taacagctac tcatgtaatc tgcagccctt
     3301 gctgtgattg cctgaaattg accctgagct gccaattgat taaattctcc tccaactccc
     3361 agcacctgag cacctgcggc aaaccagtct gacacatttg tgacagttac gccacctgtt
     3421 accatgacat caacctgcgg caaaggagat ttgattgcct taataaagga catgccaact
     3481 gtggcacctg gaaagacctt gaccatctct gcacctgatt ccaaggcagt cacgacctcc
     3541 tcaatagtca tacagcccgg aatataagca atagcatatc gatgacatag gcggcttgtc
     3601 tgcctgctaa agctaggaga cacaataaat tgagcacccg ctaaaatagc tagccttgct
     3661 gtgacatcat caagaaccgt cccagccccg atcaggatct ctggatcatt gccaactgct
     3721 tcacgcaggc ctgcaataac ctgactggca aagggattag tataggccac ctcaatggtt
     3781 ttgatcccac cttcaatacc tgctaggctg caagccattg cttctttttt agaagctccc
     3841 cgaacgacta aggctaattt attggctttt agccttaaca tgatttctga ttttctcata
     3901 ttaccttctt acctctcggt ttcccttcat caccctatca acctgactaa caggaacaaa
     3961 gagctgatca tcagcaactg tacacttaag actagctgtc gcagcagcaa aatcaagcgc
     4021 agcagcaata gcctgtcctc tcatcaattg atataagcag cctgcaacaa aggcatcacc
     4081 actgccaact cgttgcaaaa caggcgttga tagctcaatg gagcgatgta actgcccatc
     4141 ataggcatag gctaggtaat gattgattcc ttggtcatcg atgtgacgtt ccgtgtgaaa
     4201 aatggctttt aagtgatatg cctcatataa ggcagccaag cgctccttga cagcaccttg
     4261 acctgcctta gctctatcaa acatggcatg atcagcttga ttacacatta agggctccat
     4321 accaaagatc aggtctgcat actgtgcaaa atgagagaac aatgtctttg cctccctgac
     4381 tgaaatcatc gagctgcgaa aattcaaatc aaaggaaaca cagacctgcc gcttcattgc
     4441 ctcaatagcc agctgctcaa caaggtcctg actgactttt cctaaagcca aggtaatgcc
     4501 actaaaatga aaatgagtaa cttcctcaaa tagtttacca taatccagat cttttgggcc
     4561 caataaacta aagctagagg cagagcgatc ataagcgacc tgactaggac ggcagccaaa
     4621 gccattttcc aaataataaa taccaacccg atcaccacac cattgcacat gctctgtggc
     4681 aacaccgctt tgcttcaaaa aggcctcaac gcttcgtcca acctgattat caggaagggc
     4741 agtcagcagg ctactctctg ctctaaagcc actaagcgtt cttgcaatat taacctctga
     4801 gccaccataa tacagctgtg cttgacaggc atgtcctaac gtctgaaaat gactgggact
     4861 gatgcgaatc agcggctctc ccaccaataa taccttggtc ataggggtat cctttctata
     4921 gctgcagata agacttattg ctgaaggact tctcttaggt agtcgacaag gtctgatggc
     4981 tcggcattag caaagaaata atgctggaag tgctctccag aaatggtttc cttcaagaaa
     5041 tcttgatcaa tctcctttaa cacctccaac aaagaacgat aagtcacagc cttcaattcg
     5101 ctcaaaattc tagcgttacg ttgctctggg atggcccgct ctttgggata gccgcccccc
     5161 atcggctcag caaataagcg ctcaaacatc agggtcaggt taagctctgc cccccaacca
     5221 aagccctttg caaatggaat agacaaggca ttgccaccat taatctgagc aaaaaggtag
     5281 gcttctgttg gctcactagc aaagccacag gtcacacctg gaaagctatt taaggccagc
     5341 atagcaccca caccagtccc acagcccgtt acaacaaaat cagctgcctt acttgtcaat
     5401 aaaatagaag ctagtagccc gttttgcaca taggtcagct gactttcgcc ctccttgcca
     5461 tacataccat agttaaagac ctcatagcca tgcttattag taacagagac taaggtctcg
     5521 taaataatac tgtttttagc tgcttgactg ttttcattaa ttaatgcaat tttcatcttc
     5581 tgtaatctcc tttgatgctt ttttgtttct ttacggttgt ttgccaatgt aagctaaaat
     5641 gcctccatca acataaagga tatgcccatt gacaaagtta ctcgcctcac tagccaaaaa
     5701 tatagctgga ccagccagat ctgctggtgt tccccaacgc gctgccggag tcttagcaat
     5761 aataaactga tcaaaggggt gacggctgcc atcagcctga cgctctctta aaggtgctgt
     5821 ctgaggcgtt gcaatatagc caggcccaat gccattgcac tggatattgg cttctccaaa
     5881 ttctgaagcg atgtttttgg ttaacatctt aagaccaccc ttagctgccg cataagcact
     5941 aaccgtttca cgaccaagct cactcatcat cgaacagata ttgatgattt tcccatgccc
     6001 ttttttaatc attgatggca gaactgcctt tgaaacaata aatggcgcat tcaggtctat
     6061 atctaccacc tgacgaaaat ccttagccgt catctcaagc atcggtgtcc gtttaatgat
     6121 acctgcatta ttcacaagaa tatcaataat accaacctct ttttcaatct gagccaccat
     6181 ctcttgaatc cctacttcat cagtgacatc acaaacatag ccatgagctt taatgccaaa
     6241 ctctcgataa gctgctaatc cttgatccac taaatcctgc ttgatgtcat taaagacgat
     6301 ctttgctcca gccatggcat aggccttagc aatctcaaag ccaatcccat acgaggctcc
     6361 cgttatcaag gcaattttgc cctctaaaga aaagaaatgt tccattgttt tacctctcaa
     6421 tctcaatatt taagtaaacc tgtttatcaa aactatagca agactaatcc attttgtcaa
     6481 tcattttagt aaaaacacaa aaaagagcta aagtttttct tattgtcatt atcgaggaag
     6541 gcttcttagc tatatttttc ttgctcttac tcgctttact tcctataagg atcccaaaaa
     6601 ttaggccata ttgatcgctt attttgataa aataacaaaa aagtgttgac aaacattttt
     6661 gaaagcgcta taatttttct gagtaaaccg gtaaactaaa aaggagctta ttcatgattt
     6721 ctattattgt tattggtcat gggcattttg ccagtggtat tgtctcgtct ttagagttaa
     6781 ttgcaggcaa gcaagagggc ataactgcta ttgattttac tgctgagatg accgctgctg
     6841 atgtgcatga gcgcctatca gtagtcttac agtcaaagac tcaggcactt atgctttgtg
     6901 acttattagg cggcacccca tttaaggtag cagctacctt gatggaggag ctttctgaga
     6961 gcacacttga tgtcctgtct ggactcaatc tagccatgct aatagaagca gtctttgcta
     7021 ggcaagagca gcttgatcta gaacaaattg tcgctaagct attaaccaca gccaaggaag
     7081 ggatcagtaa ttggaaatcc ctctctggtg aggctgagga agcagacctt gatgaaggag
     7141 ggatttaatg actagacaga tcaaagaggt tacccttgag cctctcatac aagcagaggt
     7201 ctatagccag cagccatatc taacaaaagc tgatattgag gcagctattt tattagccct
     7261 taagcaaatc cgattaaaca tggattattt tggtactgat ttccctaggc cagccactaa
     7321 ggacaattgc tacccaatta tggataatac cgagtggacc aatggctttt ggaccggctg
     7381 cctatggctg gcctacgaat acactggtaa tgacactatc aagtcactag cacaggcaaa
     7441 tgacctgtcc ttcttagaac gcgtcaccaa agacattgag cttgaccatc atgatttagg
     7501 atttctttat tcaccctctt gcatggctga gtggaagctt ttaaaaacac ctgaagccag
     7561 acaggcagcc ttaaaggcag cagataaatt gattgagcgc tatcaggaaa aaggcggctt
     7621 tattcaagcc tggggacaac tcgggaaagc agaagattac cgcttaatta ttgattgtct
     7681 tttaaatatc cagctactct tttttgccag tcaagaaaca ggagatgaca ggtatcgtca
     7741 aatggctatc aatcactttt atgcctcagc caacaatgtg attcgtgatg acgcctctgc
     7801 ttatcatacc ttctactttg accctgaaac aggtgatcca atcaaaggag ttacacgcca
     7861 aggctacagt gatgactccg cctgggccag aggacaagct tggggaatct atggaattcc
     7921 cttgacctat cgcttcttga aggatccaca gctaattgcc ttatttaaag gaatgacgca
     7981 ctatttcctc aatcgcttgc ccaaggatca ggtatcctat tgggatttga tctttgaaga
     8041 tggcagtggt cagtctaagg acagctccgc aactgctatt gctgtttgtg gtattcacga
     8101 gatgttaaaa catttaccag agaatgatcc tgacaagaaa gcttatcaag ctgccatgca
     8161 ctgtatgctc agatcattaa ttgatagcta tgccaacaag gacatcaagc ctggtgctcc
     8221 acttttacgt catggcgttt actcttggca ctctggcaag ggcgttgatg agggaaatat
     8281 ctggggagat tactactatt tagaagccct gctgcgcttt tacaaggact ggacccctta
     8341 ttggtaggct gatagcattt agcctacaaa gactattgtt aaaggagata ttatgacacc
     8401 accaaacatt atcatgacca gagttgatga gcgtttgatt catggtcaag gccagctatg
     8461 gatcaaattt ttaaattgca acactgtcat tgtggctaat gatgccgttg ctgaagacaa
     8521 aatccaacag tctctgatga aacctgtcgt tccatcaagc attgccatgc gctttttttc
     8581 cattcaaaag gtgattgacg tgattcacaa agcaagccct gctcagacaa tctttattgt
     8641 tgttaaggat ttagaagaca tcaagcgctt ggttgaagga ggggtgccca ttaaagaggt
     8701 caatcttgga aacattcata aaacagacga taaaatcgcc attacccaat tcatttcgct
     8761 aggcgacaag gacaaggcta ttattcggac attgactcac gatcatcata ttgtctttaa
     8821 cactaaaaca actccagctg gcaatggtgc ctctgaggtt aatattttag attatattta
     8881 agaaaggaaa ttgatatgga tatcaatttg ttacaagcac ttttaatcgg tctttggaca
     8941 gccttttgtt tcagcggaat gttacttggt atctacacca atcgctgtat cattctgtct
     9001 tttggtgtcg gcattatctt gggggacttg ccaacagcac ttagcatggg agctatatct
     9061 gaattagctt atatgggatt tggtgtcggt gctggtggta ctgtgccacc caacccaatc
     9121 ggacctggta tctttggtac cttgatggct attaccagtg ctggtaaagt tactccggaa
     9181 gctgccttag ctctttcgac accaattgcc gttgctattc aatttcttca aacctttacc
     9241 tatacagctt ttgctggtgc tcctgaaaca gctaaaaaac agcttcaaaa agggaatatt
     9301 aaaggcttta catttgccgc caatggtacc atctgggctt ttgctgtgat tggcttagga
     9361 cttggtttat taggcgcctt gtcaatggat actttacttc atttggttga ttatatccca
     9421 cctgtcctcc taaatggatt aaccgttgct ggtaaaatgc ttcctgctat cggttttgct
     9481 atgattctat ctgttatggc taaaaaagag ctgattcctt ttgtcttaat tggttatgtc
     9541 tgtgcagctt acctgcaaat tccaaccatc ggtattgcca tcataggcat tatcttcgcc
     9601 ctaaatgaat actacaacaa accaaagcat gcaacaacag ctgaacaagg aggtcaacaa
     9661 gatgactgga tctaataagc tcacaaagcg tgattatctg aaaactgctc ttagagcctt
     9721 tttcctgcaa aatggcttta actatagcaa ttatcaagga ataggctatg ccaatgtcgt
     9781 ttacccagcc ctaaaaaagc attttggcaa tgacaaaaca ggcctttaca aagcactaga
     9841 gaacaattgt gcattttaca atacaaaccc tcatttccta ccttttatca ccagcctaca
     9901 cctggtcatg ctagaaaata atcggcctga agaagaaacc cgcaatatca agatggcact
     9961 catgggacct ctagcaggca tcggggatac ccttacgcaa ttttgtttag caccactctt
    10021 ttcgaccatt gctgcttcct tagcaagtga cggcctgatt ttggggccaa ttctcttttt
    10081 cctagccatg aatattattc taacagctat taaaattggc tctggactct atggctacaa
    10141 ggtggggaca agctttattg ataaattaag cgaacaaatg gcaattgtat ctcgcatggc
    10201 aaatattgtc ggagttacag tgattgctgg tctagctgct acttctgtta agatatctgt
    10261 tcccatcaca tttgcagcag gcaaggtcga cgctgcaaat gcagcccaaa aatttgtgac
    10321 cattcaggga atgctggata agattgcacc agctcttctg ccagccctct tcactctctt
    10381 gatgtattac ctcattaaaa cgaaaaaatg gacaacctat aaattagtta ttctaacagt
    10441 tattattggt attgttggca gctggttagg ggtgttagcc tagcagtctt agagattctg
    10501 ttaatcagta ttggagggtc tccattagcg atgagcaggt ctcttttcta ttgggcaaag
    10561 ctaagcattg acaccatcaa ctctcgtagc ctcagtcagg tcttttgccc tgtagagcct
    10621 ttaagcacaa gcctttactg ctagctgtga tgaaggcgtc ctccttctac tggcttctgg
    10681 cacaattaat cctttatatc tctacaagca catgatttag cggctgattg cgcgccaatc
    10741 ttacagaagg tcgcaactta agaaagagta ggatcatttt tgacctcttc aaaggtcata
    10801 ttcttggact gaaatattaa aacaattacc attccatatg ttataataaa actactaatg
    10861 atgacaaaaa ggggtctatg caatgcagcg caaagtaacc atcaatgata ttgctgactt
    10921 agctaaaact tcaaaaacaa ctgtttcttt ctacctcaac ggtcgatttg ataaaatgtc
    10981 tcaggagaca aaaagccgga tcaaggaggc tattgaagcc accaactaca agcctagcat
    11041 tgcagctcgc agtctcaatg ccaaggctac caaattgatc ggtgtggtta tcggtgacat
    11101 caccaatagc ttttccaacc agattgtcaa aggtattgaa agcaaggcgc aagaatttgg
    11161 ttatcagatt atcatcggca acagcaacta tgatccttca cgtgaggacg aattgattga
    11221 aaaaatgctt aacctaggtg tagatggttt tatcattcaa ccaacctcta actttagaaa
    11281 gtattcacgc atcatcgaag tgaaaaaaaa gcgcatggtt ttctttgaca gtcagctcta
    11341 tgagcatcgt acaaactggg tcaagaccaa caattatgac gctgtttatg acaccattca
    11401 gcaatgcatc accaaaggct atcaaagctt tatcatggtt actggcaatc ctaatttgct
    11461 gagcacacgc atcgagcgtg cctctggttt tattgatgtt ttagaggcta accagctcca
    11521 gtatcgtcaa atgatcatcg atgaaaacca aaccagctct caagaaattg ctcagtttct
    11581 acaaggcgca tttgataagg aacgtcacaa tctggtattt gtcccaaact gctgggctct
    11641 gcctaaggtt tttactgcca tgaaggcact aaaggtatca ttgcccgaaa ctggtctagt
    11701 tggctttgat aacatcgaat ggactcgctt gtcatcacca agtattacca ctattatcca
    11761 gcctgcttac gaagaagggg agcaagcaac cagcattttg attgatgata tcgaagggca
    11821 tagcaaggaa gccaagcaac aaatttttga ttgtcaggtt aattggcaag aatcaacctt
    11881 ctaacaggat tttttcgcct tctagacctt aaaaaatcag ccattctaat aacgatgaca
    11941 aagtaacacg aggcttaacg cttgtttgct agcatcagaa aaaacacata aatcagcctg
    12001 aactacccgg ttgatgaaac aataaaccat taagcaacgg tcttattcct cataccaaga
    12061 ggagcaaggc cgttttgacg tttttgacaa tggtcgttat tgtaaacgta acggtagtgt
    12121 attactgaca ggctcttcaa aaaagctgtc gtccttaggt catacgaggc cttcttttac
    12181 aagcgactgc tacttcttca ctactagtgt gatcttttag ccaatttctg agaacatcat
    12241 cagtaaaatc tcgcacctgc caataatggc aagcaagctt ttttgaccag caagttaatc
    12301 atgtatcact tgtgacttca actcttaact gtttgtcctt tcaagtctac tataagagga
    12361 atgaattccc aaaaagattc atcagttgct attatttagg taagagctat aagcacaatg
    12421 gctattatcc tgtgatataa taaaagacat aagggttata aaggagaaat tgtatgagtg
    12481 ataccattac atcaagccct gtggctgctt ctgctgctat tagtgaattg gtaggtgtag
    12541 acaccagtag ggttcaccaa cagtccgttg catttagtgt gaccaagggt attgcaggta
    12601 tggaaaaggg acgtcaggtc tctaatcaac tgctgcaggc tgtcagcgac tttagtcagg
    12661 cagtccttat tcaggctaat aaatttcctc agcttgcggc caaattagag aaaagagacc
    12721 tagaggaagc aacaagatag gggaataagt catgatcaaa gaagaatctg aagaaaaatt
    12781 tcttgcccta acccgacaga tcaatgagct ggagtggcta gaggaggatc ttttgtcgat
    12841 gaaacgacgg catgaacaag cagtctcgga gattcaagca gactgtcagc acctctcttt
    12901 tgcccttgag tccctattga accatatgcc tgaggactaa gctggaaagt acgcagagca
    12961 agaggccaat gaccacttga tcagacaaat ggatcgctat gttgatgagc atctggatca
    13021 cgtgtcaatc tatacgatgg gggttcgtcg tagactagag agggacaaag aagagcttat
    13081 cggtgaaagg agccgtttac gatgggagtg acctacagtg cagcagagtc aaaggccttg
    13141 attcaagcca tgacaaacaa tatccaaata gccaatgaaa taacggacag gttatcaagt
    13201 ggttgcgacc atctcattgc tagtctggat tcgggagagc tacagggagc agcctataca
    13261 gcaggtaggg gactttttac agcgatcatc attccctcta tcaaaaagct acaagcagcg
    13321 attgatgcta tccaagtgga gttgaccacc tatcaaaggg cagatgctca gattgccaga
    13381 tacggaaccc tggatcgtga tcacttaacc gagctgaaga ggctaagaga acggcaagtg
    13441 caagtgatcc aagcacagat tgatgaaaac gaatcgttta tgaagcaggt cagtagtctt
    13501 ttaaccggag actatggcac cctttggtct gatacctcta cactatacca tgccaaaaac
    13561 cagctggaaa tagggattcg agatgttacg accaaattgg aaagccttga atggtttcta
    13621 actcaaacct cagactgctt tagggacagc ttagttattt tgcggttagc cattcagggc
    13681 gcaacacagc tcagtcaggt cttcatgagc agcgacggca gctactcgac tgctggccta
    13741 gatatgagct gggtgactag cctgaagaat caaaagatta gccctgtcaa tgcctcaaag
    13801 tacactcaaa accattatca caacatactg actcagacca ttaaaaccat caaaagcagc
    13861 tctgaaaggc cactacaaaa atcagagcga cttgtagctg cctatgagga ttacctctat
    13921 tttctcaata aaacagcctt tgatgactat tggaaggcga gaagcaatta tgatggagag
    13981 tgagacctta aaaataataa atatgcaaag gaaattgagg aagacctagg gaaaaaatta
    14041 caatcgtcgg gtattaattt tcgtttgatt gtcaacaaga tgggagatga tatcctatca
    14101 gtgaatgtca atgctcccta cctttcacag gtagctggaa gtcaattaag tgctgcaata
    14161 cttgacaaca aacaatttta tgaccttgtc aatacgggtc agcccttgga tttgaagtca
    14221 aggacctatc atggccataa ctattctgtc tggtcaagac agtgggaatc agaattgcca
    14281 ggcgactatg ctggcaacta cctctatggt tatgttggta caggcttttt agatgcttca
    14341 gggacttatt taaaaacggc ggctgagatt gcccaggtct tttctgataa ggatatacca
    14401 aagtggttaa agaacttatc atcaggtcac tatggagaca atgagggtga tactcaaatg
    14461 atccaagcag gtatagatgg ttatatgaaa aggaagaagt caaaatgaag cgaaaaatcc
    14521 tgttattaat gatgttgctg gtaggtgttt tcatcttctc caaacgctat gagctttact
    14581 atttttttca aggaaaagaa tatctaaggc caaatgagag tatagagctt gcggtgagac
    14641 caaagtatga acaaatagaa tattcctctg acctatacct agaaagcgac gaaaaagtgc
    14701 tactgaagct agaaggtcgt gatatatggt ctgaatatat ttatagacgg acagacagct
    14761 atcttagtaa gataggatat cggtattcta taacagaaca ggttattgaa aaatacgatt
    14821 ccactaagga taatggtgta gttattgtag aagctggaca caagggagct actattgatg
    14881 gagatggcct catcgttccc ttgaagggga agagaaaata tagtgtgaca gaagatcatg
    14941 actatagtat caccattacc aacctgtccg atcagccggt tgcttttaga gcaatagtag
    15001 cagataggta gtatgtgcgc atgaactgct ttaggttttt ctgttattga ttttagattt
    15061 ttgttaggca tagaaaagct ccccttatag cttctagtga tggtttgttg ggtcac
//
LOCUS       DARYXS010000047        14412 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.048, whole genome shotgun sequence.
ACCESSION   DARYXS010000047 DARYXS010000000
VERSION     DARYXS010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14412
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.048"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            450..740
                     /locus_tag="TV193_001195"
     CDS             450..740
                     /locus_tag="TV193_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEL1513392.1"
                     /translation="MATLERHHKMLLLSMALGAASWLALGLISLPNLAGALGISTANA
                     NTTVNLLSAYSTVSSVVAIVGAVTGVGSIGAGIAATVLYLIKQKGKAAAALW"
     gene            754..1893
                     /locus_tag="TV193_001196"
     CDS             754..1893
                     /locus_tag="TV193_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513393.1"
                     /translation="MKHVFKYHKGDILGYLNIVGFTLLFYGSVIGMIMFRDYLTYDGA
                     GSLISTFILVSGTYHSVKSTFPYEGKRHPTFILTPYYLFKHLLLSVTKVYAFQIRVVT
                     IGIICLAIAFPEQLVWIALSVLAVFIYWLSLPLVAIFRVAGRLLNLLMIYGMYLNQEL
                     LVIACLCLNVVILVLSVTINVHYPYQWLAVRARKEEKTITLLKLVINTITDHLALMVL
                     FSIFCIAVTYFTQRLLLSFDYSSFSIPVFFLSASTYIALLEVMVGKNIKELELDRGLA
                     VLQFLNRDISVYKAYRNSQFLLSAHILAVIHTGCAIGLLPFLLNGQAALFLSNLVMIP
                     FIYFISFCYFVKSLKIVAGDLSVFRWVILVLYFILVVIAMVGSRL"
     gene            1890..2372
                     /locus_tag="TV193_001197"
     CDS             1890..2372
                     /locus_tag="TV193_001197"
                     /inference="COORDINATES: protein motif:HMM:NF014052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEL1513394.1"
                     /translation="MIMRKFLRYYISFIIFSIAIGILIGLLITSDTVILSKPERGWDF
                     TLEVLKNNSNNFLSYIFLFFLSPALQLIDLVSVVIQITLGMRKSGFLITALGLFPHGL
                     LEIPNFLFYQGLSQYMLWTVLTEKSMTSFLERERRYVRYYLISYYVLLIAGIMEGLLG
                     "
     gene            2369..2956
                     /locus_tag="TV193_001198"
     CDS             2369..2956
                     /locus_tag="TV193_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1513395.1"
                     /translation="MKIVNESKSFSNRKILNHISFDFSKGLYKVEGNNGSGKTTFLRL
                     LAGLERFDSGHRLQHKGDILYLDTNAIGVVPLTIEDNLTLLWKTFNASPDEETLSVIN
                     QFFGERLLDHYLTASVGTKAKVGLSLLFVKDWDYIFIDEALSTLDGFSLDMVAGRLLA
                     LKEKATVFYVSHNLSHQQLLSESQVIYLNGKGEIY"
     gene            2953..3435
                     /locus_tag="TV193_001199"
     CDS             2953..3435
                     /locus_tag="TV193_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513396.1"
                     /translation="MKGNPFNRNLSWLIAYVLLLSCYVFILVDGGFLKNSVQELEVLL
                     GQTSLAIKLFLMVISIAFSIISLLVEYFLSKFLVLLFIEAGIVSLNDVLTAKSVTLVI
                     HLSALLLKLSPSPLFQFVVNALGIVIMYGLSIKRQGNRTTALLFCLPFTLDILATLLL
                     "
     gene            3460..3975
                     /locus_tag="TV193_001200"
     CDS             3460..3975
                     /locus_tag="TV193_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513397.1"
                     /translation="MKKILYLSVLLGTSILATLIKIYNTFFAKLKASSGHSTGNIEID
                     ALLSESRLVLERQHAFTTNGINKLFVMMMSLMLLLALYYLIKKDLKAVYSYLLYLVLT
                     LVHAIYSFFSLSPLAKLYSDDMLGATIQTGEKAKLIFSVVLFLLYLLIVVANNRVKSS
                     VEPASSIGIDV"
     gene            4609..6243
                     /locus_tag="TV193_001201"
     CDS             4609..6243
                     /locus_tag="TV193_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513398.1"
                     /translation="MTRFFQKKQAKSLAIGFVSLFAVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRQQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDRKIKVSKAYDGKNHTLDLRVTFKTFTVTSNVRDGELYIDGERV
                     ETLKAGQLQLEEYPVTEIAKAYIKKTFPDGELTSSKHSLAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAVYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(6384..7277)
                     /locus_tag="TV193_001202"
     CDS             complement(6384..7277)
                     /locus_tag="TV193_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1513399.1"
                     /translation="MTTANKPEMGFQISFINPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLQFDQEDYPDKGILMGKPGLVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LEHRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLA
                     QEMIRVTAPSKSFKEGLQQLN"
     gene            complement(7261..7452)
                     /locus_tag="TV193_001203"
     CDS             complement(7261..7452)
                     /locus_tag="TV193_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513400.1"
                     /translation="MNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVTLAT
                     QMAINLIEKYHDWLNDNSK"
     gene            7687..9441
                     /locus_tag="TV193_001204"
     CDS             7687..9441
                     /locus_tag="TV193_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1513401.1"
                     /translation="MNKPLIKSCLLALLTLAGLTSMAAQADVNTYNQGRTYNDTPYYS
                     AYHHYYDHTRDTADNGIDNWGRLTRYHYYRETYYQLEAERQQLVRTYLELKASYDDQV
                     ALSSQRLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNFQSYQTLLQQLSMAD
                     FVSQYKDRLDTLTRLDTERARLIDTWWESDSNYSDLNTNLTLVNGYIKELNQALQELL
                     KDHQGKMTSDLQTLGDRQAELARRLTDIESRPKRQATSQPRGSQTHWRSAPRADVALW
                     NELRNEGDYASATTDNALPLQPYRADLTAVHDLEALQAQSDRAHRLRAKEIVFTLQRS
                     NISRQGDIDLSGAITAFIKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMT
                     DDQYKEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQ
                     TPYAFIKDKEAVCQAYAQMFKDMGRLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQ
                     YYHIDLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRSFLRYG
                     TYATNYSRNTFYPGYSYA"
     gene            9582..9962
                     /locus_tag="TV193_001205"
     CDS             9582..9962
                     /locus_tag="TV193_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEL1513402.1"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEVVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKFLQTAFA
                     HQGGPDGLLFQVDGVAYSKHISVS"
     gene            10000..12333
                     /locus_tag="TV193_001206"
     CDS             10000..12333
                     /locus_tag="TV193_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1513403.1"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEATTQATATAL
                     ADQEAQAGQTERQSVLQRSKSYGVKRKNRPIWLQRLEAILPSQQGPIRRFLRRYHVGK
                     ILLILMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYV
                     ELDAISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYL
                     SQEQSIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAA
                     NLTLDEAATLAGMLKGPEIYNPYYSIEKATNRRDTVLSAMVDAGKISKQQAQEAQAIG
                     MGNRLADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAG
                     MQTTFNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQ
                     AKRSPASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETIPMYQAL
                     ANSYNIPAVSILDQLGVDKAFSYGEKFGLKMSETKKELGVALGSGVTTNPLEMAQAYA
                     VFANGGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAV
                     NANVYGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSS
                     AGTASAIFSTQASYILPYTKGSQFKVDNAYAQNGISAVYGINETNTQAGIDSQSIIDS
                     LRKSAEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            12382..12534
                     /gene="rpmG"
                     /locus_tag="TV193_001207"
     CDS             12382..12534
                     /gene="rpmG"
                     /locus_tag="TV193_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1513404.1"
                     /translation="MAQKKASLACVECGSRNYSIGISSTPRPTRLEVNKFCKYCKAYT
                     LHKETR"
     gene            12546..12722
                     /gene="secE"
                     /locus_tag="TV193_001208"
     CDS             12546..12722
                     /gene="secE"
                     /locus_tag="TV193_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEL1513405.1"
                     /translation="MGFISGIFKLLRDTTWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            13113..13658
                     /gene="nusG"
                     /locus_tag="TV193_001209"
     CDS             13113..13658
                     /gene="nusG"
                     /locus_tag="TV193_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEL1513406.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDMVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
BASE COUNT         4111 a         2662 c         3212 g         4427 t
ORIGIN      
        1 gaaagtaagc ataagagcga cattgaagat tatattaatc ttgttaaaca gcttggcaac
       61 cctcagtttg cccaaattct acatcggacg ctatcagtga ttctagatag ttaatactaa
      121 aaaagtagcc caatcgtttg gtggctacag tggccaaggc caccaaatag acaaaagggc
      181 taataagaaa ataaaagctt ttcgcataat atctcacctc cttgataagg atattataca
      241 aaggggaagc ttcaatctca aacattcgca aatatgaaaa tattaacaaa agcatcatca
      301 tatttgcgaa tatcgagaat atgataattg tcgtgatata attactgtgt taatgattta
      361 gctaggcatt aataaatcta aatatagact acaggcaggt cgctcgttat actagtttga
      421 gggccaatgg tctgggtagg aggaagcgta tggcgacatt agagcgacat cataaaatgt
      481 tattattgtc aatggcatta ggggcagcga gctggttagc actcggattg attagcttgc
      541 caaatcttgc aggtgcttta ggaataagta ctgctaatgc caatactaca gttaatttgt
      601 tgagtgctta tagtacagtt tctagcgttg ttgcaatcgt tggtgctgtt acgggtgtag
      661 ggtctattgg agctggaatt gcagctaccg ttttatacct tatcaaacaa aaaggaaagg
      721 ctgctgctgc tctctggtag ttaattgtct gatatgaagc atgttttcaa atatcataaa
      781 ggcgacattt tagggtatct caatattgtt gggtttaccc ttttgtttta tggctcagtg
      841 ataggtatga taatgttcag ggattatttg acctatgatg gagctggttc tctaatatcg
      901 acctttattc tggtatcagg aacctatcat tctgtgaaat caacatttcc atatgaaggg
      961 aagcgtcatc caacttttat attaacaccc tattatctat ttaagcatct attgctttca
     1021 gttacaaagg tttatgcttt ccagatccga gtggttacta taggaatcat ctgtttagca
     1081 atagcctttc cggagcagct tgtttggata gccttgtctg tgctagcagt atttatatat
     1141 tggctatcgc ttccgctagt agccattttt cgagtagctg gacgactcct gaatcttctc
     1201 atgatttatg gtatgtatct taatcaggag ctgctggtca ttgcttgtct ttgtttaaat
     1261 gtggttattc ttgtgcttag tgttacgatt aatgtacatt atccctacca atggctggcg
     1321 gtgagagcta ggaaggaaga aaaaacaatt accttgttaa agcttgttat caatacgata
     1381 acagatcatt tagctttaat ggttctgttt agtattttct gtatagctgt gacctatttc
     1441 acgcaaaggc tgctgctaag ttttgattat tctagcttta gcataccagt ttttttctta
     1501 tctgcttcta cctatatcgc gttactagag gttatggtcg gtaaaaatat taaggagctt
     1561 gagttagacc ggggcttggc tgttttacag tttctgaata gggatatcag tgtttacaaa
     1621 gcttatcgca acagccaatt cttgctttct gctcacatct tagctgttat tcatacagga
     1681 tgtgccatag gcttactacc atttttacta aatggtcaag ctgctctttt tctgtctaac
     1741 ctagtgatga tccccttcat ctactttata tcattttgct atttcgtgaa atcactaaaa
     1801 atagttgctg gtgatttgtc agtgtttagg tgggttattc tggttttgta ttttatacta
     1861 gtggtcattg caatggtagg tagtcgttta tgataatgag gaaattttta agatattata
     1921 tcagttttat tattttctca atagcaattg ggattttaat cggtttgctg atcaccagtg
     1981 atactgtcat attatctaag ccagagcggg gctgggattt tactctggag gttttgaaga
     2041 ataatagcaa taattttttg tcctatattt tcctcttctt tttgtcccca gccttgcaat
     2101 tgattgattt ggtatcagtt gttatacaaa ttactctagg aatgaggaag tctggatttc
     2161 taataactgc cttgggtttg tttccgcatg gtttgctgga gatccctaat tttctctttt
     2221 atcaaggctt gagtcaatat atgctatgga ctgttttgac tgaaaaaagc atgacgtcct
     2281 tcttagaaag agaaagaaga tatgtaaggt actatcttat atcgtattat gttttgttaa
     2341 ttgctggtat tatggaaggg ttactcggat gaaaatagta aatgaaagca agtcattttc
     2401 aaacagaaaa atcttaaatc acatatcctt tgactttagt aaagggctgt ataaggttga
     2461 agggaataat ggtagtggta aaaccacttt tttgcgcttg ttagcaggct tagaacggtt
     2521 tgatagcggc catcgcttac agcataaggg agatattcta tatcttgata ctaatgctat
     2581 cggtgtagtt cccttaacta ttgaagacaa tctgacatta ttatggaaaa cctttaatgc
     2641 ctctcctgat gaggagacct tgtctgtgat taatcagttc tttggagaac ggttactaga
     2701 tcattatctg acggcttctg taggaacaaa ggctaaggtg ggcttatcct tgctttttgt
     2761 aaaggattgg gattatattt tcatagacga agccctatca acgcttgatg ggtttagtct
     2821 tgatatggtt gcaggaagat tattagcatt aaaagaaaag gctactgttt tttacgtttc
     2881 tcataatcta tcacaccagc agctattgtc agaatcacag gtgatttatc ttaatggaaa
     2941 aggagaaatc tattgaaagg taatcctttt aatcgtaatc tttcttggtt aatagcctat
     3001 gtgctattac tttcttgtta tgtattcata ttagtagatg gtggtttttt aaaaaacagc
     3061 gttcaagaat tggaagtcct gctcggccaa acatcactag ctataaagct gtttttgatg
     3121 gtgatatcaa tagcttttag catcatatct ttactggttg agtatttttt aagcaaattt
     3181 ttagtgctgc tttttattga agctggcatc gtttctttaa atgatgttct tactgctaaa
     3241 tcagtgactt tagtgatcca tttatctgct ttgctattga agctatctcc ctctccactt
     3301 tttcagtttg tagtgaatgc tttagggatt gtgatcatgt atggattgag tatcaagaga
     3361 caaggaaata ggacaactgc tcttttgttt tgtttaccct ttacactgga tattctagca
     3421 acattgttgc tttagtgatt ttgagttgga ggaaaagtaa tgaaaaaaat cttatattta
     3481 tcagtacttt taggaacgtc aattctagca acattgatta aaatttataa cacttttttt
     3541 gcaaagctaa aggcttcatc aggtcattca actgggaata tagagattga tgccctttta
     3601 tctgagtcta gactagtgtt ggaaaggcag catgccttca caacaaatgg aatcaacaag
     3661 ctattcgtta tgatgatgag tctaatgctg ttattagcct tatactatct gataaaaaag
     3721 gatttgaagg ccgtctatag ttatttgctt tacctggtgt taaccttggt tcatgcaatt
     3781 tatagcttct tttcgttaag tcccttggca aagctttatt ctgatgatat gctgggggct
     3841 acaatccaga cgggagagaa agctaaattg attttttcag tggttctttt tcttctttat
     3901 ctgcttattg ttgtggccaa taatagagta aaatctagtg tagaacccgc ttcatctatt
     3961 gggatagatg tgtaatacct ttcatattat gacctttaaa gccttttagc ttctctaatt
     4021 ttcagagtaa ctaggaggct gtttgtgacg ctctgagcgt tttttcgttt ctatcaaagt
     4081 ttagctgcgt taatgctatc tatttccgta gctgagatac aagatattat aatatgtgtt
     4141 gtcataccat aaaaacacct tacaggatat tttatgatca atcctccttg aattaagctt
     4201 tctttaagca agggtgtgta tactagccgt aatcctaaat aattggttac ctaatgataa
     4261 ctaatttttt cataacctcc ttcctaaaaa cgatgtcagg gcagtcagga ttgattgctg
     4321 ttatggcatc gtttttgttg tactttgata ggggatctag ctgtatgtta aatagcctat
     4381 caggattgag tggcgaagat gatcaggagt ctcttggctc taggttatgc tgctgtttca
     4441 tgagaaacag ctcttgatga tcaatttagg tagtattagt ggtggtcatc ttagcctttt
     4501 aggctttgag ctgctttatg tttgctcatt tttaatatgt tagtgtttac acaaataatt
     4561 ctcatttttt gatataatag aaaaggtaag gaagggtagg agataaggat gacaagattt
     4621 tttcaaaaaa aacaggccaa aagcttagcc attggttttg tgagcttgtt tgctgtgctc
     4681 attgggtatg gagcttttca ctattctaag gccagtcgta tcaatgccta tctacaagca
     4741 aggtcatcag gctctgggca ggtgcttgaa aatatcaagg aatacctcgt gtgggcagat
     4801 accaatgagc agctgaccaa tgatcaagca agatacacca gctttaagag atacagtaag
     4861 gcagagctag taagcaagcg tcagcagctg caaacagcaa ctgcagctga tgatatgtat
     4921 gtcaaatcgg ttggtcgcaa atttttgatt ttccctgatt atcgcatagc agtgaagcct
     4981 gtagccttga caatcaagac caatgtgcca aatgttgata tcttgttgaa ccataaaaag
     5041 attgctgtat cacagtcaga ggattttagc acaactattg aaagactgcc ggctgctgat
     5101 tataaggcga gtattaatgg ctattataag gatcgtaaga ttaaagtcag caaggcctat
     5161 gatggcaaga accatacact agatttgagg gttaccttta agacatttac ggtaaccagc
     5221 aatgtcagag atggcgagct ttatattgat ggcgagcgcg tggaaacttt gaaggctggg
     5281 cagcttcagc tggaagaata ccctgtgaca gaaatcgcaa aggcctatat taaaaagacc
     5341 tttcctgatg gcgagctaac ctccagcaag cattcccttg ctcctgttgc tgagggctcc
     5401 cagctagaga ttaacattga tcacctcttg actgaggaac aggcgggaca ggtgttggtg
     5461 gcagcctttg atcaattgct cacctatctc aatcaagggc aggatccagc aggtctttca
     5521 actgtttttg agcaaggggc taataatgct ttttacaaag gcttgaagga ttccatcaaa
     5581 gcaaaatttc aaactgatac cagaaaggct tctcggttaa gcattccgtc tattttgtta
     5641 agtaagctaa ctcaaattgg taagcagtct tatctagtgg actttacagc tgtttatgat
     5701 tttgtttacg ataaggaaac tgatcctgaa aaaggcacct cagggaatgt tcgtcaagac
     5761 ttgactggta agctgaccct gaaaaaatct ggggatagct accttgttag tcagtctggt
     5821 cctaaaaata ttacagttgc cagcgaaaaa aatcaggtca agccgtctat tttcccagag
     5881 gggctagtgg gaacctggat aggacatcgt tcggacatga cctttacgat gatattggct
     5941 aaggacggca gcatcacaac aaccattgga aacaaaaatg ggaatggctc acagaccact
     6001 aagtctgcta aaattaccaa ggtagaggaa aaaggagatg gcttgttcct ctacactgta
     6061 gctccagatg ctgatatagc agctcttgtt ccaggaggtg gattgggtgg tgtcaatgtc
     6121 aaatacgctt ttggtgtcaa atggagtgga gatgtcgcta cgatagtggt ttggcagaca
     6181 gcaaataatg cggcatttga ttacagtaag ccaatgcttg gccctgacat gaaaaagcaa
     6241 taagtacttt accctacaag ttggtctagc atttattgct aggaggaatc agcataaaga
     6301 aaaagcctct cttttaatct tttgtggtta agaagagagg ctttttagta tagggctgac
     6361 tgtatgagga gcaaccgatg taatcaattt agctgctgta gtccttcttt aaagctttta
     6421 gacggggcag tgaccctaat catctcttga gccaaggggt gtctaagggt tagctgatga
     6481 gcgtgcagca tgagacgctc cgctttttgc ctgctataga ggggatcacc aattagaggg
     6541 tgtttatgat gagcgagatg tactctgatt tgatgtgttc gtcctgtctc taggcgacag
     6601 ttgactaggc aggtctgatc aaaggcttgt aataaggcta gatgggtgat tgcctcttgc
     6661 ccatgcttac tatcaaccac acgcttgcgc ctatcgtggc ggtgacgtcc gattggatcg
     6721 cgataggtta ctgtttgctg ctctagctga ccttcgatta gggcccaata atctcgctta
     6781 atgtctcgat gctccaatag gcgatttaag atcggaagga taaagggatt tttagcaaag
     6841 agaatcgctc cactagtctc catgtctaag cgatgaacca catagcaggt cttgccagta
     6901 taggcagaga catggttgag caaggcgagc tcagtgggct cattgccatg tgttttcatg
     6961 ccctcgggct tgttgacaat gatgaggtgt tcgtcctgat acaggcaatc cactaggcca
     7021 ggcttaccca ttaagatgcc tttatcaggg tagtcttctt ggtcaaattg tagcttgatg
     7081 tgatcaccct gcttgacagg gctctgccag ttaatcagct catcattgac ccaaacatgc
     7141 tttttgatgc gcaagaaatg tctgatttta cggggaatca atagcctatc ttctaataac
     7201 tccttgacag ttgtcgcttg ataggggtta atgaaggaga tctgaaagcc catctcaggc
     7261 ttatttgctg ttgtcattga gccagtcatg gtatttttca atcaaattga tggccatttg
     7321 ggttgcaaga gttacagaga aagcctcggt tccctcgcgc tcgtcactgg caacctctaa
     7381 gcgtgtctca tcatagacag ccttgaggct ctctgctgac agggtttctt taaaagcttg
     7441 aaatttgttc atgatcatgt cctacctttc taaatgtttg tgacaatgct attatagcat
     7501 atttttcatc aaagctaatc atttgctcga tgatttgtgc tgcgctaaca gcgtgattct
     7561 tttgagaaaa aataagatta gctattgtga aattgtctgt cttttattat actaagaata
     7621 gtctgataaa tatattattt aaggacacga taacattggg attatgaatc atttaggaga
     7681 atactattga acaagccatt gataaaatcc tgtttgcttg ctctattgac cttggccggc
     7741 ttgaccagta tggcagcaca ggctgatgtc aacacttaca accaaggtag gacatataac
     7801 gatacaccct attattctgc ttatcatcac tactatgacc acacgaggga tactgctgac
     7861 aatggtattg ataattgggg tcgtctgaca cgctatcact attacagaga gacctattat
     7921 cagcttgagg ccgagcgtca gcagcttgtt aggacttact tggagttgaa ggcttcatat
     7981 gatgatcagg tggctcttag cagtcaacga ctacagcagt accagtctgg ctggtctgat
     8041 ctccaatcac gctttgagca gctcaggaaa accaatcctg ttgtaggcgg tgattatcgg
     8101 attgttgagc tagagggcaa ttttcaaagc tatcagacct tgctgcagca gctttctatg
     8161 gctgattttg tcagccagta caaagatagg ctggatacct tgactagact tgatacagag
     8221 cgagctaggc tcattgacac ctggtgggaa agtgatagca attactcaga tctcaatacc
     8281 aatctaacac tagtcaatgg ctatatcaag gagctgaatc aggctttaca ggagcttctt
     8341 aaggaccatc aaggtaaaat gacatcagat ctgcagacct tgggtgaccg acaggccgag
     8401 cttgctagac ggctgacaga tatagaaagc aggcctaaga gacaggctac cagtcaacct
     8461 cgtggttcac agacacattg gcgatcagcc cctagagctg atgttgcctt gtggaatgaa
     8521 ttgcgaaacg aaggagatta tgcttctgct acgacagaca atgctttgcc attgcagcct
     8581 tatcgagcgg acttaacagc tgttcatgat ctagaagcct tgcaagcaca atctgataga
     8641 gcacaccgct tgcgggcaaa ggaaattgtc tttacactgc agcgttctaa cattagtcgt
     8701 cagggcgata tagatttgtc aggagccatt acagcattta tcaaagaaaa gcttctcgtc
     8761 actccaaatg cgcgtggggt atcatctggc tttaggtggc aaatgcaaac ctatgacaat
     8821 gagcgcttaa ccatcactct aatgcctcaa tattatatga ctgatgatca gtacaaggag
     8881 tattacgacc atctcaaggc ttggacagct cagcatatcc agtctaccga tacagaggtt
     8941 gagaaaattg ataagattca agactatatc atgacaaact accactatgc gaccggcaag
     9001 gttggaggag tgacccgtac tggcatttct gtgcagacgc catatgcctt tatcaaggac
     9061 aaggaggctg tttgtcaggc ctatgcacag atgtttaagg acatgggacg actagctgga
     9121 cttgatgttc attatattca aggctatgga gacccagttg gcggcttatc aagtctacat
     9181 gcttggaata tcgtcaaggt tgatggtcaa tattatcata ttgacctgac ttggaatgat
     9241 actattgaca gcaccaatca caatcatacc tacaccctgc gaggcaatga ttttatgagc
     9301 aaaacacatt tgtggaatgc tgcctatgcg atctcagata gtgactatgc tgcttatcct
     9361 aggaggagct tcctgagata tgggacctat gcgactaact attcaagaaa tacattttat
     9421 ccaggataca gttatgctta ataatagcta ataccatcaa aagccctaga aagcttgctt
     9481 gattctttca gggctttttg atatgtcatg gtttttggta taggattttg aaagaaattg
     9541 ttataatagg ataaaatgct tatgtaacag gagaaaataa aatgaagagt attagacgct
     9601 atgatgtcaa tgaagagtgg gcacatactg gcttagtaga ggcaggcgat ttttattttt
     9661 taaattattg tgtaggaaat gtcggtcaag atattgaggc tcaaattaac ggtgcctttg
     9721 atgaaatgga gcgtcgtttg gggctggtag ggctgacgct agaggtcgtt gttcaaatgg
     9781 attgcttgtt tagagacatt tggaatgtgc cagttatgga aaaaatcatc aaggagcgat
     9841 ttaatggcaa atacccggct cgtaaatttc ttcaaacagc ctttgctcat cagggtggtc
     9901 cggacggctt gctatttcag gtagatgggg ttgcttattc aaagcatatc tccgtatcct
     9961 aaacaatatg acttggaggc ttagtagtat cataaggcta tgacattttt agaattatta
    10021 caaaagaaat tttttccaaa aaaataccaa gaaaaacagg ccttaaagga aagggcagcc
    10081 cagcatatgg ctgacaaaga ggctactact caggctactg ccactgcttt ggccgatcag
    10141 gaggcacagg cagggcagac tgagaggcaa tcagtccttc aacgcagcaa gtcctatggg
    10201 gtcaaaagga aaaatcggcc gatctggctt caaaggctgg aggcgatttt gccatcgcag
    10261 caaggtccta ttcgccgctt tcttcgtcgt taccatgttg gtaaaatcct gctgattttg
    10321 atgggtacct ttgtcttgct gctggggtct tacctttttt acctttcaaa gacagctaag
    10381 gtttctgact tgcaggacgc tcttaaggcg acgacagtca tctatgaccg caagggagaa
    10441 tatgcaggca gtctttctgg tcaaaagggg acctatgtgg agcttgacgc tatttcagat
    10501 gatttggaaa aggcggttat tgccacagag gaccgtacct tttataccaa caatggtatt
    10561 aatttcaagc gctttttatt ggctattgtg accgcaggac gctttggtgg aggctcgacc
    10621 attactcagc agttggctaa aaatgcttat ttgtcccagg agcagagcat taaaagaaag
    10681 gcgcgtgagt ttttcttagc acttgaattg accaagaaat acagtaaaaa tgacattttg
    10741 accatgtatc tcaataattc ctattttgga aatggtattt ggggtgttga ggacgccagt
    10801 caaaaatatt ttggtacctc agcagctaat ctaaccttgg acgaggcagc aacccttgcc
    10861 ggtatgctca agggacctga aatttacaat ccctattact caatcgaaaa ggcaaccaac
    10921 cgtagagata ctgttttgtc agccatggtt gacgctggaa aaatcagcaa gcagcaggca
    10981 caagaggccc aagctattgg tatggggaac cgtttagcag acacctatgt cggcaagaca
    11041 gatgattatc agtacccatc ttattttgat gctgttatca atgaggctat ctcgcgctat
    11101 ggcatctcag aaaaggatat tgtcaatgat ggctacaaga tttacacaga gttggaccaa
    11161 aattaccaag caggcatgca gaccaccttt aatgaggata gcctatttcc tgtgtctgag
    11221 tttgacggca gctcagctga ggcggctagt gtggctctag atcctaaaac cggagctgtc
    11281 agggggcttg ttggtcgtgt caatagcaca gaaaaccagc cctttagaag ctttaactat
    11341 gctactcaag ccaagcgtag ccctgcttca acgatcaagc ccctagttgt ttatactcct
    11401 gctgttgcag caggctggtc actggagcac gaactgccaa acagcgttca ggattttggc
    11461 ggttatcagc cgcataatta tggcaattac gaatcagaaa caattcctat gtatcaggct
    11521 ttggctaatt cctacaatat tcctgctgtt tcaattctgg atcagttggg ggtggataag
    11581 gcctttagct atggtgaaaa atttggtttg aagatgagtg aaaccaaaaa ggagcttgga
    11641 gtggcgcttg gtagtggtgt caccaccaat ccgcttgaga tggcacaggc ctatgcagtc
    11701 tttgccaatg gtggtgtcaa gcatattgcc cacctgatta ccagaattga aaatgctaag
    11761 ggcaaggtta tcaagacctt tacagacaaa accaagcggg ttatcagtca atcagtggct
    11821 gataagatga ctagcatgat gcttggaacc ttttctaatg gtacagctgt taatgccaat
    11881 gtctatggct atactctggc tggtaaaaca gggaccacag aaactgactt taacccggac
    11941 ctttccggtg atcagtgggt cattggctac acgccagacg ttgttatcag tcaatgggtt
    12001 ggcttcaatc aaaccgatga gcatcattat ttatcagatt caagtgcggg cactgcctca
    12061 gcaattttta gcacccaagc ctcttatata ttgccatata ccaaaggaag ccaattcaag
    12121 gtcgataacg cttacgctca aaacggtatt tcagcggttt atgggattaa tgagaccaat
    12181 acgcaagcag gtattgattc tcaatccatc attgatagtc ttagaaagtc agccgaggaa
    12241 gcttcaaagt ctatttcaga ggcagttgat caatctggtc tcagagaaaa ggcgcaaagt
    12301 atctggaaga gtattgttga ctactttaga tagcttgcga aaatatctaa atcgtgttag
    12361 aataatcact acggaggcgt tatggcacag aaaaaagcaa gcctagcgtg tgtagaatgt
    12421 ggcagccgca attattctat cgggattagt agcacgccta gaccaacacg actagaagtc
    12481 aataagtttt gcaaatattg taaagcatac accttacaca aagaaacacg ttagaggaga
    12541 gcctgatggg attcattagt gggattttta agcttttaag ggatacaact tggccggatc
    12601 gtaagcagcg ctggaaggac tttatttctg tccttgagta tacagcattc tttacggtaa
    12661 tcatctttat ctttgaccag ttgctatcaa aaggcatttt atcattgatt aatttattct
    12721 aagtcattgc aatgatgaga cctgttatga ttaaaattgc ttggaaaagc ctaggctgaa
    12781 acaatcgttt cggccttttt gagtgcgatg ggcaggttgt actctgatag atgcaagacc
    12841 aatagaccac ctactatgcg ggtgcgtaaa ggggttgata gctaccgata gttaagggct
    12901 atagcaagta gaaaggcttg cagctcagct gatccgctgt tatgactaaa ggcattgacc
    12961 agaaaggttc gttggcagcc aacaaagtgc tcttaccctg ctatgagggg ctattaatgc
    13021 gttgacagcc aatccttctt ctattataat gaaagtgtga taacagcaat gcaaaggcca
    13081 gcagaggctt ttttataatg aaaggaagta acatgttaga ttcttttgat aagggctggt
    13141 ttgtccttca aacttactca ggctatgaaa ataaagtaaa agaaaacctt ttgcagcgtg
    13201 ctcaaaccta taacatgcta gacaatattc tccgcgttga gattcctacc caaacggtaa
    13261 atgttgaaaa aaatggtcag gtcaaagagg ttgaggaaaa ccgcttccca ggatatgttt
    13321 tggttgagat ggttatgact gatgacgctt ggtttgttgt tcgtaacaca ccaaatgtga
    13381 caggctttgt cggatcgcat gggaaccgct caaaaccaac ccctctactt gaagaggaga
    13441 ttcgtgctat cctgttgtca atgggacaaa ctgttgatgt ctttgatacc aacattaaag
    13501 agggcgatat ggttcaaatc attgatggcg cctttatcgg gcaagagggt cgtgtcgtag
    13561 aaattgaaaa caacaaggtc aagctcatgc ttaatatgtt tggctcagaa accttagcag
    13621 aggtcgagct ttaccaaatc gcagagctat cgtcctgata ggctcctaaa gctattattc
    13681 ataccataaa aaataaaagg ctggcatcgg ctctctaaaa taccgatgtt aggccttttt
    13741 tgttggtctt ctacaaccaa gactcaaatt aaccaaaccc taaaaagagt catttttcct
    13801 tcgcttttta agtctctaac tgatcgccct agcttatttt taatctagta atcgcaacag
    13861 gtcaagagtt aaatgatatc gcgccgttat tgattggtat agacaaaaat acgctcaaaa
    13921 aaagaaaaaa ggataggtaa tatagtcctg gtttgcttga tagatggtgg ttggcaacca
    13981 accattcgag tactttcctt aactataaac tcctaatcaa ttctagcgtt taaaaaataa
    14041 gattattctt ggagggaagc aaagagcttc tctccttttt gagttgtagc attcttgatc
    14101 ctgatcttat aagcagagtc ctgtttgccg ggctgttgag atgaataagg gcatttctat
    14161 agtgattata tagtgttgca gatgtgtgta tggtttaagg tctaaatacc cttcaagctt
    14221 agttcttggg tagtcagttc ggattggctg gctgattttt aagcctttaa tggcttagtg
    14281 gtaagacaaa ccagattaca tttgctaaaa agtccctaag gctacaatca ttttttgtga
    14341 ctaatataaa aactagacct tttgggattt gtaataattt agattattgt ttttaaaatt
    14401 agcaaatatt aa
//
LOCUS       DARYXS010000048        14271 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.049, whole genome shotgun sequence.
ACCESSION   DARYXS010000048 DARYXS010000000
VERSION     DARYXS010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14271
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.049"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..255
                     /locus_tag="TV193_001210"
     CDS             <1..255
                     /locus_tag="TV193_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL1513407.1"
                     /translation="QFTRAGIIENLIFKGFVERDKKNLIATHKGISLVAIVADNFKSA
                     ETTAKWEMELSDIAQGKSSKEEFLEAIENEIKEAVSTYSK"
     gene            339..518
                     /locus_tag="TV193_001211"
     CDS             339..518
                     /locus_tag="TV193_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEL1513408.1"
                     /translation="MKDTFIDTAKVMSKGQVTIPKRIRELLNLENGDYVTFVVNKDRV
                     EIQNSNVFIEENIKK"
     gene            537..1964
                     /locus_tag="TV193_001212"
     CDS             537..1964
                     /locus_tag="TV193_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1513409.1"
                     /translation="MTIDEIKKLIQAGEKIDVEFKESKNALTKDVFDTVCSFNNRNGG
                     HILLGANDKREIVGVSEDKVDKVIKEFTTAINNPQKMYPPLYLLPETFEIEGKQVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQGSYFVNKVYPNLDIDFL
                     DASVIDKAKKMAVFRNKNHVWENMSNEELLRSANLILTDPETKREGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIEFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDERITVENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGQNPLFEEGDIFRTIIPLKKIA
                     TQKVGGDNVAHDVAQGVAHDVAHDKIALAEFIKEKVRSNDRITRKAIADEAGVSVKTI
                     ERAIKEIDNLKYVGSGNSGHWELNE"
     gene            2136..8966
                     /locus_tag="TV193_001213"
                     /pseudo
     CDS             2136..8966
                     /locus_tag="TV193_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            9476..11241
                     /locus_tag="TV193_001214"
                     /pseudo
     CDS             9476..11241
                     /locus_tag="TV193_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678622.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
     gene            11349..13259
                     /locus_tag="TV193_001215"
                     /pseudo
     CDS             11349..13259
                     /locus_tag="TV193_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            13303..13962
                     /locus_tag="TV193_001216"
     CDS             13303..13962
                     /locus_tag="TV193_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1513410.1"
                     /translation="MDYKTMRNQIEDMANDNHKDFVKAIISVEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLINIVGNIVGKVDVAEREN
                     KNGEAFKVANFSVVSKDDEGNKVYHNCSAYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNVRILSSKLLKAKEQMKGQEEKKESVLGAIKKYQSEDKEKPKEKRDASKEAE
                     R"
     gene            14112..>14271
                     /locus_tag="TV193_001217"
     CDS             14112..>14271
                     /locus_tag="TV193_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1513411.1"
                     /translation="MSKISYKKLFKKMIDLDMKNSELMEKAEVSRSTFYKMKNSENIT
                     TDVIVRICD"
BASE COUNT         5251 a         2064 c         3203 g         3753 t
ORIGIN      
        1 cagttcacaa gggcagggat tattgaaaac ttaatcttta agggatttgt agaaagagat
       61 aagaaaaacc ttatagccac acataaagga ataagccttg tagcgattgt agctgataac
      121 tttaagtcgg cagaaactac cgcaaaatgg gaaatggaat tatccgatat tgctcaaggg
      181 aaatcttcaa aggaagaatt tttagaagcg attgaaaatg agataaaaga agcggtttca
      241 acttatagta agtaagatga cactaatttc agagtagaaa aaatatctta aaagtgctat
      301 aatcttttgt aggaaaagta gggcgaaagg gattagtcat gaaagataca tttatagata
      361 ctgctaaagt tatgtcaaaa ggacaggtta ctattccaaa gaggattagg gaacttttga
      421 atttagaaaa tggagactat gttacttttg tagttaataa agatagagtt gaaattcaaa
      481 attccaatgt ttttatcgaa gaaaacatta agaaataaag gtggtgaaat aaacagatga
      541 cgatagatga aattaagaag ttaattcaag ccggagaaaa aatagatgtc gaatttaaag
      601 aatccaagaa cgctttaacc aaagatgtct ttgatacagt atgctctttc aacaatagaa
      661 atggcggaca tattttactt ggtgcaaatg ataaaagaga gatcgttggt gttagtgaag
      721 ataaagtaga taaagtgatt aaggaattta ctacggcaat caacaatccg caaaagatgt
      781 atccaccact ttatttgctg ccggaaactt ttgaaattga ggggaaacaa gttatttata
      841 taagagttcc tgaaggttat caggtatgca gacataacgg aagaatttgg gataggtctt
      901 atgaagggga catcaatatc acagatcatt cagagcttgt atataagcta tatgcaagaa
      961 aacaaggaag ctattttgtt aataaggtat atccgaatct tgatattgat tttcttgatg
     1021 cttctgtcat tgataaagct aagaaaatgg ctgttttccg aaataaaaat catgtttggg
     1081 aaaatatgag taatgaggag cttcttagaa gtgccaattt gatactgaca gatccggaaa
     1141 caaagcgtga aggaatcaca ttagctgcta ttttgttatt tggaaaagat aactctatta
     1201 tgtccgttct tccgcaacac aaaactgatg ctatattcag ggttgaaaat aaggatagat
     1261 atgatgatag agatgttgtc ataacaaatc tgattgacag ctatgacaga ctgatagaat
     1321 ttggacaaaa gcacttgaat gatttatttg tcttggacgg aattgtcaat gtcaatgcaa
     1381 gagacaggat actcagagaa atagtttcca atacgctggc tcatagagat tattcaagtg
     1441 gttttcctgc aaagatgatt attgacgatg agaggattac agttgaaaac agcaacttgg
     1501 ctcatgggat gggagcttta gatttacaga agtttgagcc atttcctaaa aatcctgcta
     1561 tatctaaagt ttttagagaa ataggtcttg cggatgaact tggttcagga atgcgaaata
     1621 cctacaaata cacacagctt tattcaggac aaaacccgct atttgaggag ggagatatat
     1681 tcagaacgat tattcctcta aagaagatag cgacacaaaa ggttggaggc gacaatgtcg
     1741 ctcacgatgt cgctcagggt gtcgctcacg atgtcgctca cgataagata gctctcgcag
     1801 agtttattaa agaaaaagtg agaagcaatg ataggattac aagaaaggct attgcagatg
     1861 aagctggagt tagcgtaaag actatcgaaa gagctataaa ggaaatagat aatctgaagt
     1921 atgtaggaag tggtaatagc ggacactggg aactgaatga ataaaattaa gttgcaaaac
     1981 aaagattttt ataaataaga gggtgctatg aataccataa aatgaggatt tgtagtagga
     2041 aatttaagtt gcagcaagtt gcaatacaca gaatcaaaag gtgattagag taaaatctaa
     2101 ccgccttttt tgtttggaaa aagaaggagg taaaaatgcg aataaatgat tttcataaca
     2161 ttttggagct tgtaaaacaa aatattttgc aaagtgaagc agaatacctg aagctcctaa
     2221 aggttgtcgg aaacaatcaa agatatgact ttagaagtca gttaagtatt tatgatagaa
     2281 attctgaagc gacagcctgt gccaagttcg actattggag ggaacgcttt aaccgtactg
     2341 ttatgagagg acaaaaaggt atccccattt tagaggacta cggcacatac aaaaaagtgg
     2401 catatatctt tgatataagt cagacggttt caagaaatag ggatgtcaat gaggtcaatc
     2461 tttggagatt tgataaagaa gctcataggg atgtcttaaa ggaaatgata aaaaacgagg
     2521 gctatgagga aagtgaaagc accttagaaa atatcttttc tttaagtaga ctctacggtg
     2581 atgaaaagat agacagcctt atgaatgagc ttagaatagc tgatgaggat agaatatctt
     2641 ttaccaagtt tgtgagggac tcagtgagtt atgcagtagc ttcaagattt aatgtagact
     2701 atcctatgga taatgagctt ctaaaggaaa actttgcaat gcttgatagc atttccctta
     2761 tgagtcttgg tgaaatcgta tcggatatta gtggaaagat tattgatgaa accattcaaa
     2821 aaagcaaaga gcttgagctt caaaaagaag ttttaagagg aaaagaagca ggatataata
     2881 ggattaaaga aaaaattgag aaaggagata atgatgtact tcgacgagat gatcaggaaa
     2941 gaaatgaaaa tgagcgagtt ctccgaaatg gagagtacgg acgagataat agagaaaatc
     3001 agggagaata cactaaacag cttggaggaa cagacggact tcataaggga gtatccgaat
     3061 ccgacctacg cagtaatgag gctggattac ctttcagaga gcgaggagca gagccacttc
     3121 gagatgttag tggatctata caaggagagg aagctaacag gacacctgat ggatattcag
     3181 aaacaggcga tagactttat gaggacagag aagccgaaat tgatggtagc ttggaagata
     3241 gaggacgaga acgatccgca gtatggggcg atgatttcag ctctgaagga aatgacaatc
     3301 aaggaagtat taaaaattta aaagataata ctgagataga gataagagaa gctgaaaagg
     3361 cttctttttc tttacccgaa aattcatatg gacagatgag acttaccatt ccattaactc
     3421 agagggatat agatactgtc cttattaacg gaggaaatca cgatggaagt agacttcctg
     3481 ttatcgctga gttttctaaa ggaaaaagta atgaagaatt aggagaatac ctaaaagata
     3541 tatttagagg cggtaatgga ttttacattg atgaaagaga agtatcttcc tggtattcgg
     3601 ataaaggcat tcatttagcc tacgggacat ctgcaagaga agatactacg caaattttaa
     3661 gctggagcga tgctgcaaag aggataaatg agcttcttga taatggtgag tttgctacaa
     3721 atgtagagat ttctgaggct cctgattatg aaagagataa gatttcagag tccttatggt
     3781 atctaatgca tgatttaagc gaagaaggac aaggatattt tgaactattg aaaacaagtg
     3841 gaagaggctt tccggaagaa acaaaaagat tgtctgaagc attaaaaaat cccgactacc
     3901 taaaggaaac gatcaaagaa tacagcaggt ttttagaagg atacaaagaa aacagaaatg
     3961 tattaaggtt tcactatcac aaggtagata gcctttgtca gaggttacag gaacttgagc
     4021 tgtcacgaaa ggaatatagt accaatctaa cagagcttcc gaaggtaaag tccttcatta
     4081 cagaagatga agtccttgaa agtctttcaa gaggaagtgg cgtcgataga ggaaaagagc
     4141 gaattacaaa gtttttcaaa gaaaatcata ccttgcagga aaaagctaat ttcctaaaag
     4201 acgaatatgg cataggtggt agaagtcatg cagtatcggg ggcaatggga agtgatgaat
     4261 ggcatgatgc aaaggggctt aaattacaga agaataattg taatgatgtt tttcttactt
     4321 ggtcaagtgt ggcaaagcgt atagaggagc tgctttctaa aaatctgtat gaagaaaaga
     4381 aaatagaaag taagtcagag gtagaagaat caaaagagct acaatattat tctaaagata
     4441 atcctgaaaa cttaatgact gatgaaatgc ttgaaagagt gcctgagctt tacgcacagg
     4501 aagatgtagc tttagcggat aaagaggttc atgcagcata tattattcct ttccgttcta
     4561 actggacttg gtatatgacg gaatatgata gggaaagcgg tgatgccttt ggacttgtgt
     4621 taggatttga acctgaatgg ggatatttca atcttgaaga attgaaagaa ttaaatgctc
     4681 aaaggcttat tttagaggat tttccaaaga cttttagaga gcttaaagat acagaacttg
     4741 caaagcagat ggatgaacag gaacttcaat cagtctttaa cggagaactt agctttgaag
     4801 ataaagaaga acttgaaata tctgaagaag tggaagaaag agtagctgca acacctgttc
     4861 aggaaacact atttgattat ctgaaggaga aggaagaagt agagcttaac gaagaaaaga
     4921 aaagtatttc agatgaattt gcagttaaag agggcgatac cgtctatttt aatcatgaag
     4981 aatatactgt aagggaaatt gctgaaaata aaatcacaga aagatatgac ttatggcttg
     5041 atccgggaag aagtggaaac catcaaatcc ctattgtagc ctttacagat aatgaagatt
     5101 tattaagaca agtaagccct gaaagacctg cgtttatcgt tggagatgaa attaaataca
     5161 aggataaaga ctataccatc acacgctttg acgatatggg aaataatcta aagacggtaa
     5221 cggttaagga taataccgaa tatcttggcg gtatgataac aggctcagat gtaattcctt
     5281 atcgtcttga aagcgatctt gagagggtat ttgaaaatct gacatataaa aagcctgaaa
     5341 ctattgctaa agaaagtgaa ataaagaaag cagaagctca taacttcaag attacggaag
     5401 aaacattacc tgacaagtta tctccaagtg aaaggctaaa taataacctt gaagccatct
     5461 ctatgctgag tcgcatcgaa agtggacaaa gagagtttga cagtacagct caggaagttt
     5521 tagcaaggta tgtaggctgg ggtggacttg ctgatgtatt cgatgaagaa aaaggcggac
     5581 agtggaaaga agcgaggagc tttctaaagg aaaacttatc tcaggcagaa tatgaagctg
     5641 caagagaatc taccctaacg agcttttaca caccgaaaac tgttattgac ggcgtatata
     5701 agacactttc cgatatggga tttaagagcg gaaatatcct tgagccatca atgggcatcg
     5761 gaaactttat aggaaatctt cctgatgaaa tgaacaagtc aaagttttat ggtgtagagc
     5821 ttgacagtat aagcggtagg attggaaaac ttttataccc tgaaagtgat atacagatta
     5881 aaggacttga agaaacttct ttttccaata acttttttga tgttgcaatc ggcaatgttc
     5941 cctttggaga atacaaagta aatgacaggg aatacaatcg taataacttc cttattcatg
     6001 actatttctt tgccaagtcc attgataagg ttagaaacgg cggggttatc gcctttatta
     6061 catcaagtgg aacaatggat aaaaaggatg aaagtgtaag acgctatctt gcagcaagag
     6121 cagagttttt aggagctatc agacttccta atgacacctt taagggtact gccggcacag
     6181 aagtaacctc agatattatc ttcttaaaga aaagagatag cgtattagag cgtgatgaag
     6241 attggataca ccttgcggaa gatgaaaacg gtcttgtata taacaaatac tttgttgatc
     6301 atcctgaaca ggtacttggc tcaatgcgtg aagtaagcgg aagatttgga aaaactctaa
     6361 cttgtgaacc gatatcttat ttaggcacag agctaaatat ggcttcatta aaggatcgta
     6421 tcgagattgc aggagaaaga atttcaaaag atgccaagta tgaagaaata gagcttttag
     6481 atgatgaaat cacttcaatc cctgcaacgg atgatgttaa gaacttttcc tataccatta
     6541 ttgatgatga agtctattac agagaaaact cactgtttat caaaaaggaa gtaaccgata
     6601 aaaacaaaga aaaaatcaag gattatcttg agctgaatgc tgccttaaaa aatgtgattt
     6661 acaagcagaa agaaggtttt agtgaggaag aaatcaaggc ttcacaggaa aaactaaatg
     6721 aagtctatga ccgtttttct aataagcatg gctttgtaaa taatttaagc aatacaagag
     6781 ctttaaaaga ggatagcaac ttcccgcttg tttcctccat tgaaatcctt gatgaagaaa
     6841 actttaaggc aaagggagat attttctcca aaagaactat tacaaaggct aaagtcatag
     6901 atcatgtgga tacttcttta gaagcccttg tcttatcggt atctgaaaaa ggatatgtgg
     6961 actttgacta tatggaaggt cttacaggaa aagacagacc gactttgatt gaggagcttc
     7021 gaggggaaat ctacttaaat attagggaag aacaaaactt ttatagacct ctatccttta
     7081 accccgaaga tggagatttg ccttttgcct gtgccaatgg cagtaattcc tacaaatacg
     7141 gctatgtaac aaaggatgaa tatttaagtg ggaatatcag ggacaagatt gccatagtag
     7201 atagctatct atcaaagctc agacagacgg aaagagagtt acctcatctt ggctatgcag
     7261 aagatggtaa agaaaaagag ctgattagct atgagatgaa tcgtttggaa taccaaaagg
     7321 ctgagcttac aaaagttcta ccaaaggagc ttgaagcaag tgagataagt gttcgtcttg
     7381 gtgcgacttg gataccgatt aaagatattg aaaaatttat ttttgaaacg ctgaaaactc
     7441 cgggatatgc aagatgggat attaaggtta agttttcaaa cctgacaagt gagtggaata
     7501 tagaaggtaa aagtagggat agaggaaatg acctcgctga aatgacttac ggtacatcaa
     7561 gggtaaatgc ctataagctg attgaagatg ccttaaacct gaaagaaaca aaggtatttg
     7621 accagattgt aaatccggac ggctctaaaa cttctgtact aaataaaaaa gaaaccatgc
     7681 ttgcagggca aaagcaggaa ctactaaaag aagaatttaa gaactggata tttaatgatc
     7741 aggagagaag aaaccgtctt gtaaaactgt ataatgagcg ttttaactct atccgaaaca
     7801 gagaatatga cggaagtaat ctttcctttg agggaatgaa tactaaaata gatttaagac
     7861 ctcatcagag aaatgccata gcaagaagtc tttatggagg caacaccctg cttgctcatg
     7921 tggtgggcag tggaaagacc tttgaaatgg tggcttccgc aatggaaagt aaaagacttg
     7981 gaatgtgtag taagtccttg tttgttgtac ccaatcactt aacaggacaa atcggtcgtg
     8041 agtttatgca gctatatccg tcggcaaata tcatggtggc agataagaaa gattttgagc
     8101 cgaagaaccg taagcgtttt atcggtcgaa ttgccacagg agaatacgat gccgttgtta
     8161 tcgggcatac gcagtttgaa aaaattccta tgtctaagga atatcaggag aagcatatcc
     8221 aagatcagat tgatgaaatc gtaaactatg tagaagaata caagcatgac agaaatcaga
     8281 actttacagt aaaacagctt gaaaagacaa agaaaaaact ggaaacaagg cttgagaaat
     8341 taaatgacga ttttaagaaa gatgatgtca ttacctttga ggaattagga gttgataagc
     8401 tctttgttga tgaagcacac aactacaaaa atctctatct ttatacaaaa atgcgtaatg
     8461 ttgcaggaat cggtcaaagt gaagccttta agtcctccga tatgtttatg aagtgtcgct
     8521 atatggatga aatgacaaac ggaaaaggca ttgtctttgc aacgggaacg cctgtatcaa
     8581 actccatgac tgagctttac actatgcagc gttatcttca gtatgagagc ttaaagaaaa
     8641 ataatctgga gcattttgat agctgggctt ctacttttgg ggaaacgcag tctgcttttg
     8701 agctttctcc ggagggaaca ggatacagag taaagacaag attttccaag ttctataact
     8761 tgcctgaact aatgtctatg tttaaggaag tcgctgacat tcaaacagcg gatatgttaa
     8821 atcttccaac acctgaggca cattatgaag taattaagac cttgccaagt gaggagcaaa
     8881 aggaaattct aaagagcctt tctgaaagag cagatgatgt gagaaatagg gtggtagagc
     8941 ctgacaaaga taatatgcta aaaattgtgc gctgttaagc gtaaaaatgt atctccctca
     9001 cagagggata ttattgaaag taaataatag gaacaactaa ctaacctagc ggggaaaccc
     9061 aaaggggaca atagcatgtt agtaaagcgg ataaggagtg agttacaacg ctttgatgtg
     9121 ccgcaagttc cgtaacctat ggttaaggct aaactgcttg aacctcaatt ctgactaggt
     9181 gcaaagcatc gcccatcgga aagtaactga gaccgatgtt actgtatatt cgttgttgtg
     9241 attttggacg aataactttc tacagtaaaa gagcatacga taagtatgaa taaaggaatg
     9301 agtgaggaac ctaagggtta ctagaacgta catttttaac gaatagcagg attgcctaag
     9361 aggggggacc cttatggtaa cggagtcacc gtagtagtcc gagcaaggga aatccttgta
     9421 catggcgaag ggtgacaggt aatttcgatt agttagaaag gattaggtgc gtgggatgcg
     9481 tacagccaaa actattttaa cggtcattca tgaacgtgga aaacaagata aaccactcga
     9541 aagggtttat aagttactat ttaatcgtga actctatctg atagcctatg caaagttata
     9601 cccgaataat ggagcaatga caaagggtgt tacagaggaa acgattgatg gaatgtctat
     9661 tcaaaaaata gatatgatta ttgaacaatt aagacaagaa acctattact ggagaccagc
     9721 taggagagag tacattccta aaaagaatgg aaaacaccgt cctttgggaa taccagtatg
     9781 gagtgataaa cttcttcagg aagtgattcg catgatatta gaagcctatt atgagccaca
     9841 atttagtgaa cattctcatg gttttagacc aaaaagaggg tgtcatacag ctttacaaga
     9901 aattcagact tggaaaggga cacgttggtt catagaagga gatatctcta gttattttga
     9961 cacgattgac cacgatgtat taatcactat gttgtctaga caaattcagg atggtcggtt
    10021 tattaggctt atcaaaaata tgcttgaggc aggatatctt gatgattgga agtttcacaa
    10081 gactattagt ggaacaccgc aaggtggagt tattagtcct ttattagcta atatctattt
    10141 acatcaattt gataagtggg tcggtgaaga gctgatacct caatatacaa gaggtaaaaa
    10201 gcagaaagca aactcagcct ataatcgttt gagtagaaga attaaatgct atcaggataa
    10261 aggagattat aaaaaagctc atcagttaat tgttgagaga agaaatctcc cttcagttga
    10321 tacttatgat accagctatc ggagattaag atatgttcgg tatgcggatg actttattct
    10381 aggctttaca ggttcaaaag ctgaggcaaa ggctataaag aagcaaattg gagacttttt
    10441 aaatactaag ttatctttgg aactttctca agaaaagact ttgattaccc atgcgactgg
    10501 agaatcagct aaatttctgg gatatgagat aaaagcacaa cgtgtcaatg attatattga
    10561 taacaaaggg agacagagtg ccaatggtgt tatcgcatta tttgtacctg catcagttat
    10621 tgaaagcaaa tgccgccaat acatgaaaaa tggtaaagct attcatcgta ataacttatt
    10681 gcatgatgat gactttagta tcgttcaaac ttaccaacaa gaatatagag ggctagttca
    10741 atattatata ttggcacaaa atttgtcatg gttctcaaaa gtctattggt atatggaaac
    10801 atcactcctt aaaacattag catttaaaca tgagtcatcc attaataaaa tgttagctaa
    10861 atataagact accacaacta gcacgaatgg ccgaacggtg ccgtgtttac aggtagttgt
    10921 gtctcgagaa gataaacctc ctctagttgc aacgtggggt ggcataaaaa gaaagctgta
    10981 atagaagatg ctccgtatca agtttatggt ggtcgaacag agcttatcaa gcgattactc
    11041 gcaaataagt gtgagctatg tggaagtgag gagaacatag aggtacatca tatcagaaaa
    11101 ttagcagact tgaacaaaca caatgggaaa ttagttccaa agtggaaaga aatcatgtca
    11161 gcaagacgtc gaaaaatgct agtgacttgt cgggattgtc accatgcaat acataatggt
    11221 tcaataaata cacgtttatg aaatgaaatt actggagagc cggatgatgc gaaagtatca
    11281 tgtccggttc ggtgggggga taatggaaaa ggggtcgcaa tgactacctc gctagtatcc
    11341 taccctacac taatgatggt aaaaaacttg ccttagatca gcgtttaatt aatcctctgc
    11401 tacctgacaa tcctgacagt aaggtcaatg tctgtgtgaa aaatgtcttt agtatatggg
    11461 ataagacaaa agaagataag tcaacacagc tactattttc tgatatgtct acaccaaaag
    11521 gcgatggaga atttaacatc tatgatgata ttagagaaaa acttgtagca atgggaatac
    11581 caaaagaaga aatcgccttt atccacgaag cgaattccga taaacaaaag gacgaactct
    11641 ttgcaaaggt gcgtaaagga gatgtgagga tattacttgg ttctactcag aaaatgggag
    11701 ccggcacgaa tgtacaaaac aaactgattg cccttcatga tttggatgtt ccttggcgtc
    11761 ctgccgattt agagcagcgt gcgggcagaa ttgtaagaca gggcaatgaa aacaaggaag
    11821 taaatatcta tcgttatgtt acggagaaca cctttgatgc gtatttgtgg cagacaatag
    11881 agaataagca gaagttcatt tctcagatta tgacaagtaa aacacctgtc agagtggcag
    11941 aagatgtgga tgaaagttca cttaactatg cagaaattaa agcccttgcc acaggtgatc
    12001 cgaagattaa agaaaagatg gatttggata atgaggttac gaaacttaaa atgcttgaag
    12061 caaactataa gtccaaccgt tacagattag aggataaagt ggcgaaaaac tatcctgaag
    12121 aaatcgcaag aactgaaaag ctcatagaag ctgtcaagaa agatatatct gatgtagagc
    12181 ctaaagcgga cggagaggaa aagtttactt ctattactat cgcaggagca aagattaccg
    12241 ataagaaatt agcaggagaa agattgcttg aagctatttc aaaggttaaa atcaatgaaa
    12301 gtaaggtaat cggtaagtac agaaatatgg acttggaagc aagttataac ttctttacta
    12361 attctcataa tttcagctta aacggtgttg caaagcattc aggagagctt ggcacaagtg
    12421 ctgacggtaa tattacaaga cttgataacg ctcttgagaa aatgcctgag aaattaaaga
    12481 ggcttgaaga aaagctcata agcaccaaag agcagcttga aaatgccaaa gaggaattaa
    12541 aaaagccgtt tgaaaaagct gatgaattaa agagtaaggt gcttcgcttg gctgaactaa
    12601 ataagctact tgatatgggt gatgtggaag aaaagagaaa tgataatccc cttgtagaag
    12661 atgttaaaag ggcaattatt gatttctgta acagagaata tgaagaaaat catagctacg
    12721 atgagtttga tgctctatat cctgacttaa agcatatagg aattgcctat accaacacgc
    12781 cggatgaaag acacagcatt caatatgagc ttaatttaga ggataagata tggacacagt
    12841 atattgatga tatatctata aaaactgaga gctttgacta tgagaacaaa ggagagaatg
    12901 aaactctaag aaatatgaaa aatgagattg agctatcctc ttttgaagat ctggtttatg
    12961 tggattcaga agatttgaaa gcagcaacgg gacttgatat tgatgacgaa ggtaacttct
    13021 atgatccgct ttctaaagac cttgataatg acggaattac tgaccgttac gataatgact
    13081 ttaaggacag cgactatttt gaatcaacat atgatgtgga ggataatttt catagcaaag
    13141 aagaaagttc acaaaaatca gaggataagc catctatttt aggacagata agagcctatc
    13201 aggaagaaag taaaacagaa gaaaaacaaa ctacaaaaga acaggaattt ttaagataag
    13261 gggagggtaa cctccctttt actatgaaag gagataaaaa acatggatta caaaacaatg
    13321 agaaatcaaa tagaagatat ggcaaatgat aaccacaagg actttgtaaa agcgattata
    13381 agcgtggaga aaggtatcaa tgatgaaagt gctttggaca agctctatga cgcttatatg
    13441 gacaatgaca gtctgaattt actgcatgag gaatttgact acatgattga agatttacga
    13501 gaacaggggc aaataaaaga cctgccctat gttcaggaag agaaagataa tcttatcaat
    13561 atcgttggaa atattgtagg aaaggttgat gtagctgaaa gagaaaacaa gaatggagaa
    13621 gcctttaagg tggcaaattt ctctgttgta tctaaagatg atgagggaaa taaggtttat
    13681 cataattgct ccgcttatgg agaaaagagt gatattccaa aagactttaa gcagggagat
    13741 tttgtaaagc tctttggaca aatcagaact tccattgatg ataatggcaa ggagcatagc
    13801 aatgtaagga tactttcttc aaagctctta aaggcaaagg aacaaatgaa aggacaagaa
    13861 gaaaagaaag aatctgttct tggagctatc aagaaatatc agtctgaaga taaggaaaaa
    13921 ccaaaagaaa agagagacgc aagcaaagaa gctgagagat aaatatatgg tcggtgtggt
    13981 cttaggactg caccgactct tttttgtcta tctaaatgtc gtgtgtttgt gtaaaaggaa
    14041 gtttgtagtg aaaaaagtga ataaatatga tataatgata aaaacaaaat catatgcatg
    14101 ggaggacaat cgtgtcgaaa ataagttata aaaagctatt taaaaaaatg atagatttag
    14161 atatgaaaaa ttctgagcta atggaaaaag cagaagttag ccggagtact ttttataaaa
    14221 tgaagaacag tgagaatatt actactgatg tgattgtcag aatatgtgat a
//
LOCUS       DARYXS010000049        14073 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.050, whole genome shotgun sequence.
ACCESSION   DARYXS010000049 DARYXS010000000
VERSION     DARYXS010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14073
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.050"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            134..694
                     /gene="ahpC"
                     /locus_tag="TV193_001218"
     CDS             134..694
                     /gene="ahpC"
                     /locus_tag="TV193_001218"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEL1513412.1"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYEILKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASSLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            715..2247
                     /gene="ahpF"
                     /locus_tag="TV193_001219"
     CDS             715..2247
                     /gene="ahpF"
                     /locus_tag="TV193_001219"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEL1513413.1"
                     /translation="MALSPDIKEQLAQYLNLLESDLVLQAYLGSDDSSQKVKDFIEEI
                     AAMSDRITVEETTLTRQPSFKITQKGQDSGVIFAGLPLGHEFASFILALLQVSGRAPK
                     IEQDIIDRIRAIDRPLSFETYVSLTCHNCPDVVQALNIMAVLNKNISHTMVEGGMFQE
                     EVKAKGIMSVPTVFLNGEEFTSGRATIEQLLEQIAGPLSKEAFADKGVYDVLVIGGGP
                     AGNSAAIYAARKGLNTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAQVEEHTKSY
                     DVDIIKAQLATSIEKKDLVEVTLANGAVLKAKTAILALGAKWRSINVPGENEFKNKGV
                     TYCPHCDGPLFEDKNVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTDNMTILKNVATKDIVGDDHVTGLNYIERDSNQEKHLDLEGVFVQIGLVPNTAWLK
                     DSGISLTDRGEIIVDKYGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            2708..3478
                     /gene="rpsB"
                     /locus_tag="TV193_001220"
     CDS             2708..3478
                     /gene="rpsB"
                     /locus_tag="TV193_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEL1513414.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLA
                     DAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA"
     gene            3646..4686
                     /locus_tag="TV193_001221"
     CDS             3646..4686
                     /locus_tag="TV193_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEL1513415.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATAKAIAE
                     GKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGAYQHNG
                     GRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAIELDNE
                     SRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(4886..6781)
                     /locus_tag="TV193_001222"
     CDS             complement(4886..6781)
                     /locus_tag="TV193_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HEL1513416.1"
                     /translation="MTTYQEDFYQAVNGQWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEVKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDNIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHAYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFNIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(7333..8265)
                     /locus_tag="TV193_001223"
     CDS             complement(7333..8265)
                     /locus_tag="TV193_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEL1513417.1"
                     /translation="MTRASQEMRHVYRDFLIAANQEHPEVVVLEADLSSSMATNHLDQ
                     VFGKRYINVGIMEAEMVGLAAGLAIKGYKPYLHTFGPFASRRVFDQLFLSLAYAQLGA
                     TVIGSDAGVSAEMNGGTHMPFEDLGLLRLIPRAIVYEVSDDVQFKAVLKETLSLDGLK
                     YIRTIRKKPEAIYQGHEDFSNGYCLLRQGKDLVLACSGIMVKRCLEVADKMAEQGYSI
                     GVIDVFRVKPLADELKGLLTGSPVLTVENHNRIGGLGSAICELLAQESNTPVYRMGVD
                     ERFGQVGQMDYLLEEYQLTPAAIEQQVLRILAAD"
     gene            complement(8262..9119)
                     /locus_tag="TV193_001224"
     CDS             complement(8262..9119)
                     /locus_tag="TV193_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1513418.1"
                     /translation="MVLSDEPLTDVKRFAAEIRLNTLETLNHLGFGHYGGSLSIVELL
                     AVLYGEIMPMTPELFVQSDRDYLVLSKGHAGPALYSTLYLKGFFDKAFLQSLNTNGTS
                     LPSHPDRLLTPGIDMTTGSLGQGISVATGIAYAQALEQSPHYTYAIVGDGELNEGQCW
                     EAIQLAAHQQLSHFIVFVDDNKKQLDGTTEAICRPGDFVEKFTAFGFESLRVDGRDVQ
                     AIFEAIRALQASSSHKPKCIVLDTVKGQGVSQLESMAANHHLRPTAAEKEMLAAAVRK
                     LRASLEVTR"
     gene            complement(9122..10465)
                     /locus_tag="TV193_001225"
     CDS             complement(9122..10465)
                     /locus_tag="TV193_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEL1513419.1"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGLTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDIDFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPTWISKELSSGTHGLVFALQLAGQFAAGVFVILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIAYPYAPNAVLIGFVSSFVGGLVSMAVMIVS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVILAGLVGLSVVGKSVAKEE"
     gene            complement(10478..10765)
                     /locus_tag="TV193_001226"
     CDS             complement(10478..10765)
                     /locus_tag="TV193_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1513420.1"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAEHLGDVRILNSIIDMDELTSLVKAICQEKGLV"
     gene            complement(10767..12809)
                     /locus_tag="TV193_001227"
     CDS             complement(10767..12809)
                     /locus_tag="TV193_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1513421.1"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELNE
                     FLAQHELSELDATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELKYTRASGYILVGDEINKHRLA
                     LVMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQVCLY
                     AVIFILCRYQRRVDRVKQRQVVVSEQLDQLTALLVAEIMQQLSLKYQLFEADEAYFQL
                     LLAGCFEGEGTVGDDFFESLTVAIVDQMQGVALLSFSQADQLKENLKRHLIPAYYRLR
                     YGLPSDNDYTLRIKDSYSELFDLVKQSLEPLAKELGSPIPDSEIAYFVLHFGGYLKQQ
                     GRDFHRQAYQAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDKSGYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQGVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGTFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASKSFEDIKTIIAEEA"
     gene            13332..13922
                     /locus_tag="TV193_001228"
     CDS             13332..13922
                     /locus_tag="TV193_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513422.1"
                     /translation="MKKVKQLIIAMIASLLLIANTVPSIVYASEVTKIQQEEKVIEEK
                     LSQPLEISKSELDTLIQEKKALYPNLTEQEMREIAYKAMSPYTFRASVWDGQGVTLDE
                     FAWAFDVIVGGLISGYATIGKYVAKHGVAAARAVLSRAAKAAAQRLGVLTGFISGLLR
                     AAFSVINIYYNVGYALAQYVDARDYHPNNGRINAWA"
BASE COUNT         4353 a         3178 c         2770 g         3772 t
ORIGIN      
        1 tgtgactaaa ttcacatatg aaattgttag aaaagaacat caaaaacctt gataaatcta
       61 gggtttacaa gtggacagat aagatttctt agcttataat acaggtatca aatgtaaaaa
      121 aggaggacat gacatgtctt tagtaggaaa ggaaattgct gaattttcag cccaagcttt
      181 tcacaatgga aaatttatca ctgtaactaa tgaggatctt aaagggaaat gggcagttgt
      241 ttgcttctac ccagcagact tttcttttgt ttgcccaaca gagctaggtg accttcaaga
      301 gcaatatgaa atactaaaat ctttaggtgt tgaggtttat tctgtatcta ctgatacaca
      361 ctttgttcat aaggcatggc acgatgattc agatgttgtc ggaacaatca cttacccaat
      421 gattggtgac ccatcacatg ctatttcaca agcctttgat gttcttggtg aggatggact
      481 tgctcaacgc ggtactttca ttattgatcc agatggtgtt atccaaatga tggaaatcaa
      541 tgctgatggt atcggacgtg atgcaagcag cttgattgat aagattcgtg ctgctcagta
      601 cgttcgtaag cacccaggtg aagtatgccc agccaaatgg aaagaagggg ctgaaacact
      661 aacacctagc cttgaccttg tcggcaaaat ttaagcaggc aaaggagaaa agctatggca
      721 ttaagtcctg atattaaaga gcagcttgct caatacctta atcttttgga atctgactta
      781 gtcctacaag cttatcttgg tagtgacgat agctcacaaa aggtcaagga cttcattgaa
      841 gaaattgctg ccatgtcaga ccgtatcact gttgaggaga ctaccctaac acgtcaacca
      901 agctttaaga ttacccaaaa aggtcaagac agcggagtga tctttgctgg actgcctcta
      961 ggtcacgagt ttgcctcctt tatccttgct ctattacagg tttcaggacg tgcaccaaag
     1021 attgagcagg atattattga ccgcatcagg gctattgacc gtcctttaag ctttgaaacc
     1081 tatgtcagct taacgtgtca taattgccca gatgtggtcc aagccttgaa cattatggct
     1141 gttcttaata agaacatttc acatactatg gttgagggtg gtatgttcca agaggaagtc
     1201 aaggcaaagg gcatcatgtc tgtgccaact gtctttttga atggagaaga attcacctct
     1261 ggtcgcgcca ctattgagca gctgcttgag caaatcgcag gacctctatc taaggaggcc
     1321 tttgctgata aaggagtcta tgacgtcctt gtcattggtg gaggacctgc aggaaatagt
     1381 gctgccatct atgctgctcg taaaggctta aatacaggtc ttttggctga gacctttggt
     1441 ggtcaagtca tggaaactgt aggtatcgaa aacatgatag gaaccctgta tacagaggga
     1501 ccaaagctta tggcccaggt tgaggagcat actaaatcct atgatgttga catcatcaaa
     1561 gcccagctgg ctacttcgat tgagaaaaaa gaccttgttg aggttactct tgctaatggc
     1621 gctgtcttga aggctaaaac agctattcta gcgcttggtg caaaatggcg cagtatcaat
     1681 gttcctggcg aaaatgagtt taaaaataaa ggagtaacct actgcccaca ctgtgacggt
     1741 cctctctttg aagataaaaa cgttgctgtt atcggtggtg gtaactctgg acttgaggct
     1801 gcacttgatt tagctggctt agctaagcat gtctatgttc ttgagttctt acctgagctt
     1861 aaggccgaca aggtgctaca ggatcgcgct gctaaaacag acaatatgac tattctaaaa
     1921 aatgttgcta caaaggatat tgttggggac gatcatgtca cagggcttaa ctatatcgag
     1981 cgtgacagca atcaagaaaa gcatcttgac cttgaaggag tctttgtaca gattggcttg
     2041 gtgccaaata cagcttggct caaagacagc ggtatcagct taaccgatcg tggcgagatt
     2101 attgttgata aatatggttc aaccaatatt ccaggtatct ttgccgcagg cgactgtaca
     2161 gattcagcct acaaacaaat tattatttct atggggtcag gtgctactgc tgctattgga
     2221 gcatttgatt acctgattcg tcagtaagtt agcaaaaaac caaggtaact gtttaccctg
     2281 gtttttgctt tttagaggcc taataaacag caaggctgat agatcaagca tttggggtac
     2341 gccaaatgct tgaagaaact tatgttctct gatatctttt catgattcat gtgttctttt
     2401 tcagaaagat tgatagtaaa actaagctgc gcttgaaaaa tggatcgtgt caaaacgtca
     2461 acatatcaaa aatgcattga aaacatgcat atggttagaa aataatggca tgcattttcc
     2521 tcatgcgtac gacgtgggtt ttagtgtatt taggcttgct atgactagct ttttttggta
     2581 tactgttgta gttgtgcaga caacaaatac tcatcttaga tcgattgtga ttctgttgcc
     2641 atcaggtgga gttgcaagcc gacgtctaag agaggaaaaa aacatttcta taaaggagaa
     2701 actactcatg gcagtaattt caatgaaaca acttcttgag gctggtgttc actttggtca
     2761 ccaaactcgt cgctggaacc ctaagatggc taaatacatc ttcacagagc gtaacggtat
     2821 ccacgttatc gacttgcaac aaactgtaaa attagctgat caagcttacg agtttgttcg
     2881 tgatgcagca gctaatgacg ctgttatctt gtttgttggt actaaaaagc aagctgctga
     2941 agcagttgct gacgaagcta ctcgtgcagg tcaatacttc atcaaccacc gctggttggg
     3001 tggaactctt acaaactggg gaactatcca aaagcgtatc gctcgtttga aagaaatcaa
     3061 acgcatggaa gaagaaggaa cctttgaggt tcttcctaag aaagaggttg cacttcttaa
     3121 caagcaacgc gcacgtcttg aaaaattctt aggtggtatt gaggatatgc ctcgtatccc
     3181 agatgtgatg tacgttgttg acccacacaa agaacaaatc gctgttaaag aagctaagaa
     3241 gcttggtatt ccagttgtgg caatggttga tacaaatgct gacccagatg acattgatgt
     3301 gatcattcca gctaacgacg acgctatccg cgctgtcaaa ttaatcactg ctaaattggc
     3361 tgatgctgtt atcgaaggcc gtcaaggtga agacgcagag gttgcatttg aagctgatac
     3421 tcaagcagag tcaatcgaag aaatcgttga ggttgttgaa ggttcaaacg aagcttaagt
     3481 caggcttatt gaactaggat agcttcttgc tattcataac atggtctaac ggggcaaagc
     3541 attccgctct atctcgttat tttttaagta agaaaaccca gcaggtcaaa ggctctgcta
     3601 aagcgagctt taagaggacc gattctaatt ttggaggaaa taaaaatggc agaaattaca
     3661 gctaagcttg taaaagaatt gcgtgaaaaa tctggtgccg gcgttatgga cgctaaaaaa
     3721 gcacttgttg aaacagatgg cgacatggaa aaggctattg agcttcttcg tgaaaagggt
     3781 atggcaaagg ccgctaaaaa agctgaccgc gttgctgctg aaggcttgac aggtgtttat
     3841 gttaatggta acgttgctgc tgttgttgag gtcaatgctg aaactgactt cgttgccaaa
     3901 aacgctcaat tcgttgaatt ggtaaacgca actgcaaagg ctatcgcaga aggtaagcca
     3961 gctaataacg acgaagcact tgctcttatc atgccttctg gtgaaacact tgctgatgct
     4021 tatgtcaatg caacagctac aatcggtgaa aaaatctcat tccgtcgctt tgccctagtt
     4081 gaaaaaactg atgaccaaca ctttggcgct taccaacaca atggcggccg tattggcgtt
     4141 atcactgttg ttgaaggcgg agacgaagca cttgccaagc aagtatcaat gcacgtcgca
     4201 gctatgaagc caactgtttt atcatacact gagcttgacc cacaatttat caaggacgag
     4261 ttggcacaat tgaaccacgc tattgagctt gacaatgaat cacgtgcaat ggttaacaag
     4321 ccagcacttc cattcttgaa atatggttca aaggctcaat tatcagctga cgtgattgcg
     4381 caagctgaag aagacatcaa ggctgagctt gctgctgaag gtaagcctga aaagatctgg
     4441 gacaaaatta tcccaggtaa gatggatcgc ttcatgcttg ataacactaa ggttgaccaa
     4501 gcctatactc ttcttgctca ggtttacatc atggacgaca gcaaaacggt tgaagcatac
     4561 cttgactcag tcaatgctaa agcgattagc tttgctcgct ttgaagtcgg tgaaggtatt
     4621 gagaaaaaag ctaacgactt tgaatcagag gttgctgcta caatggcagc tgcgcttaac
     4681 aactagtcta atcataagtc ataagattga ggacagcttt taagagctat cttcaatctt
     4741 tttttacgcc taaaaaaaga gcttttcgag cctatccaac acaaaaagac taagagaagc
     4801 atgccttcct ccacaagcta gactatacgt tctaacgata ggagggccgt acaaagcctc
     4861 ttagtctttt tttaatgagc aatgattacc aaataatcac acgatcctct ggagcacgcc
     4921 acattggatc accttcttta atgttaaatt cttggtggaa ttcatcaaag tttgtcaagg
     4981 tcacattagt acgccattga ccaggtgcgt ggacgtcaat acttgccatc atttgcatga
     5041 attcctcacg cgccttcata cgccagatgg tggcaaagtt gataaagaaa tctctggcag
     5101 aaaaatctgg ctctgactga gctgcctcta aggcacaggc aacaccacct aggtcagcaa
     5161 cattttcaga cactgttaat ttaccattga ctttagcacc ataggagtca aggccatcaa
     5221 attgctctac aattttatcg gtacgctcct tgaaggcggc ataatcctcg tctgtccacc
     5281 aattctttag gctaccatgc tcatcaaagg aagcaccgtt ggtatcaaag gcatgcgaaa
     5341 tttcatgagc aataacagca ccgataccac cataattagc tgatgagctt tgactcaacg
     5401 aataaaacgg cgcctgcaga atagctgctg ggaacacaat ttggttttgc tgtgggtcat
     5461 aataagcatt aaccatgttg gcaggcatgt gccattcact acgatccaca ggcttattcc
     5521 acttgctcca tgaatgagca attgaaattt tggctaaatt ctgagcattt tcaacaagtg
     5581 atagcttatc atcgatgacc tttttagcat aggtttctgg taatttttcc ggatagccaa
     5641 tgtgtggggt gataacattt agctttgtaa tggctttctc acgtgttgct ggtgcaagcc
     5701 aatccgcagt ttcaagacga gatttataaa cctcaatcat cttagctacc ttgtgttcaa
     5761 catcagcctt agcctctggt gaaaattttt caccagcata ccaaagccca agagcttgat
     5821 taaatggtcc ttgtgctaag taataggctg cttttttctt gtccatagcc tgtggagttc
     5881 ctgacaaggc acgactgtaa actcctgata gcacacgaat ctcgtcagtc aaataagcat
     5941 gataagcacc tgctgctgta agcactagcc aggcttttag cagctcccaa ttcttctcag
     6001 aataatagtc agctgcaaat tctgtccaga accgctcctc tggcacaaca accttgtctg
     6061 gtacttcacc taaaatcaca gtaaatatat tatctaaagg caattctggc actagcttgg
     6121 taaactcggc ccagtcataa gggtggtaaa gcttggcata ctctgaatat tcctcacgag
     6181 aaaggacata atctgccagc tgtttatcaa gcgtgataac cttatccagc aagtccttaa
     6241 cctcttcatg tgaaaagcca aatttaggca atagctcctc ttgcatgcca cgccagatag
     6301 caagcagctc tttgcctttg tcattgtctt tggcatagta agtggtatct ggcaggataa
     6361 gacctggtgc ctctgcccaa aggacattta actgagcatt cataaagtct ggtgctacac
     6421 taaatggaaa ctgatttggt tttccattta gctcataatc agccaccttg ctagcaaact
     6481 cggcaaaaga tcctaaggcc ttgtattctt caattaagtc caaggctggc gctacgccca
     6541 cctgatcacg cttgtcataa tctgcaacca agcggtgaaa cttgacaaag ttttctaata
     6601 tagcgtcatt gggaacatgc tcaccagcca accaagcatc tgttgtggtc agcattaagt
     6661 cctcaatctc atctgctagg tctgaaaagc cccctgtacg aggcttatcg tctgggataa
     6721 cagctgtttc tgcccattga ccattgacgg cttgataaaa atcttcttga tatgttgtca
     6781 tgaattgctc cttttttaaa ttaaaccatt atgttaggac tagcttttac tcctcataat
     6841 gtaatctctt acattttacc aaaaaatcgt tcaaaatact cgttttatat taactttctg
     6901 ttcaaaaata agctcattct tcgtatcgca tggcatagat agtaaacgct tagctgcttt
     6961 ggtcctttta tcagtaagat taatcataaa aactgaacaa tcactaagaa atcaaacgat
     7021 tcttctccag cttcatgaaa acagccctca caatatgcca aaaactcagc agtaatagca
     7081 aaaggcccta tcagtcctga caaaagaatt gcaccccaaa ggtgaagata aaacctaaag
     7141 cttaagaact ttttctatga cattaaaatt agaaggtgaa atcaagagtt atcaatcatt
     7201 atttcacgcc tacagagtga aagggactga aagcgcataa ctaaaaggac tgaaccctgt
     7261 ttcatacaaa gctcaatcct aatctataag gtccagcttt ttgggtgtgg tacacctgat
     7321 aggctttttt agctaatctg ccgctaaaat cctcaaaacc tgctgctcaa tagctgctgg
     7381 cgtcagctgg tattcctcta atagataatc catctgtccg acctgaccga aacgttcgtc
     7441 cacccccata cggtaaactg gagtattact ttcctgagcc agtagctcac agatagcact
     7501 cccaagccca ccgatacgat tatgattttc aacggttaga acaggactgc ctgtaagtag
     7561 accctttagc tcatcggcca gtggctttac cctgaaaaca tcaatcacac cgatagagta
     7621 gccctgctct gccattttat cggctacctc taagcacctt ttgaccatga tccctgagca
     7681 agccagcaca aggtcttttc cttgacgcaa taggcaatag ccattagaaa agtcctcatg
     7741 cccttgataa atagcctctg gctttttacg aatggttcga atgtatttta ggccatcgag
     7801 tgatagggtt tcctttaaaa cagctttaaa ttgaacgtca tcactgacct cataaacaat
     7861 agcccttgga atcaggcgca gcagtcccag atcctcaaag ggcatatggg tgccgccatt
     7921 catttccgca ctaactccgg catcagagcc aataaccgtt gcgcctagct gggcataggc
     7981 taatgaaaga aacagctgat caaacacacg acgtgaggca aagggaccaa aggtgtgtag
     8041 gtaaggctta tagcctttaa tcgccaggcc tgctgccaga ccgaccattt ctgcttccat
     8101 aatgcctaca ttaatatagc gcttgccaaa cacctgatcc aaatggttgg tggccattga
     8161 gcttgataaa tctgcctcta agacgactac ctcagggtgc tcttggttgg ctgcaatgag
     8221 gaaatctcgg taaacatgac gcatttcttg acttgctcga gtcatcttgt cacctccaaa
     8281 ctagctcgta gctttctgac agcggcagca agcatctcct tttcggctgc tgttggtctt
     8341 agatggtggt tagctgccat tgactctagc tggctaacac cctgaccctt gacggtatct
     8401 aagacgatac acttgggctt atgacttgat gacgcctgca aagccctgat ggcttcaaaa
     8461 atagcctgaa catccctacc atctacacgt aagctttcaa agccaaatgc cgtaaacttt
     8521 tcaacaaaat cacctggacg acagattgcc tcggttgttc catctaattg cttcttattg
     8581 tcatcaacaa agacaatgaa atgacttagc tgctggtgtg ccgcaagctg gatagcctcc
     8641 cagcattggc cctcgtttaa ttccccatca ccaacgattg cataggtata atgtggtgac
     8701 tgctcaagcg cttgagcata ggcaatgccc gttgctacgc taattccctg accaagagag
     8761 cctgtcgtca tgtcaatacc aggcgttaac agacgatctg ggtgcgaggg cagacttgtt
     8821 ccattggtat taagagactg taaaaaggcc ttatcaaaaa acccctttaa gtagagagtg
     8881 ctatagaggg caggacccgc atgtcccttt gataacacca gataatctct atctgactgg
     8941 acaaagagct ctggtgtcat gggcatgatt tctccataaa gcacagccag caattctaca
     9001 atagacaagc taccgccata atgaccaaag ccaagatgat taagagtctc caaggtattt
     9061 agacgaatct ctgctgcgaa tcgcttcaca tctgttagag gctcatcact caaaaccatg
     9121 cttattcctc cttagctact gattttccaa caacagaaag cccaacaagt ccagctaata
     9181 tcacaaaaat accaatcaca atagctgtca caccacctat gctgttaagt gttcctagta
     9241 aaatacctga taagccaaaa tcggcatctg agaaggttga gccctcaaag cccaagccgc
     9301 ctaaaacagg catcaagaaa atcggaagat agctaataag aacaccctgt aaaaaggctc
     9361 ccacagttgc accgcgcaca cctccagaag cattcccaat aacaccagct gtggcaccac
     9421 agaagaaatg aggcacaacg ccaggtaaaa tcactgtcgt tccacttacg atcatcacag
     9481 ccatgctcac aaggccacca acaaagctag aaacaaagcc aatcagcact gcattggggg
     9541 cataaggata ggcaatcggg caatccaagg ccggcttaga atgtggcact aatttttcag
     9601 aaatgccctt gaaggctgga acaatttcac ccagaatcaa acgaacacca gctaaaatca
     9661 caaagacgcc tgcagcaaac tgtcctgcca actgcaaggc aaagaccaag ccatgtgtgc
     9721 cagaggataa ttccttacta atccaagtag gaccagcaaa aatagctaca atcaaataaa
     9781 tgattgccat tgataaggta atgcttactg tactatcacg caaaaaagca aggctctttg
     9841 gaaaatcaat gtcctctgtt gacttggttt tgtctccaac aagacctcct acaaaaccgc
     9901 ttaaccaata accaagagag ctaaaatgcc ccaaagcgac cttatcgtta ccagtcagct
     9961 ggatcatata ccgttgcaca agagccggtg aaacactcat gataatccct aaggccagcc
    10021 caccaaacac aatcaaggac actgacgtca agcctgcaac agacataatc acagcaatca
    10081 tacaggccat gtaaagtgtg tgatgccctg tcaagaagat atacttaaat cgggtaaagc
    10141 gagcaatcaa aatattaaag atcattcctg taaacataat cagagctgtc gctgacccat
    10201 aggtcgtcaa agcaactgca acaatagcct cattatttgg cacaacacca gacagatgaa
    10261 aggcatgctc aaacatcgtt ccaaaagggt tgagtgagcc ttgcacgata cctgcaccac
    10321 ctgaaaccac taaaaaccca acaaaggtct taatgcctcc cttaacaatg tcaggagcag
    10381 gctttttttg aagtaagaga ccaacaatag caatcaaggc aaccaaaata gctggtgtgc
    10441 taacaatatc aagtaaaaat gtcatcttat cctccttcta aacaagcccc ttttcctggc
    10501 aaatagcctt taccagacta gtcaattcgt ccatatcaat gatactattt aaaatcctca
    10561 catctcccag atgctctgcc gagtctgcca aatcacgccc aacaatccac acatctgccg
    10621 ctgtgggatc cgcgccacca agatcataat gctccacctc aacaccggtt actcccaagt
    10681 cctttaatac ggattcgata ttcatctgaa ccataaagct agaccctaag cctgaaccac
    10741 aggctgtacc aattcttaat gccattttat gcctcctctg caataatagt tttaatatcc
    10801 tcaaatgatt tagacgcaag taaagccttg acctgctcat tgtctcttaa aatggtcgtc
    10861 agccgagaca gggcctttag atgtgtttca ttatcaatag cagcaataca aattaacaaa
    10921 cgaatctcct gcttaggatc atctaacaaa taaatcgggt gctctaaaac aagcatcgac
    10981 atacctacct gattcacacc atcctctggc ctcgcatgtg ggatagcaat ccccttacct
    11041 agattaataa aagtaccaaa ctcctcaacc ttagcaatca tagcctccgg gtagctcgct
    11101 tgaatctgcc cactctctaa caagggctga gccgccaaat aaatagcctc tctccacccc
    11161 aattgctctg aggttgattg ataggttttc ttggtaatta agtcttgtaa cactggtcga
    11221 atatcctttc ttttcacacc ttgtcttaaa tattgctgca aagcaaagcg cagcttttct
    11281 ttttgatgaa tgaccgcata tgagctgata agatggagca gctcttcaac ctctagccga
    11341 tagccaatat ctggaaaatc acgattaacc aagctgacca gctgaaaagc ctgctcatca
    11401 gtcattatca tagggactaa ataaaagggc ttatcagtct ctaatcgtat cgttgaaaaa
    11461 accaaatcat agccgctctt atctaattgc ccaagctgat caagccttga aagcccccga
    11521 aaagcaatat caggaaataa aagctttaaa tgctccttga tcattaaaga agaactaaca
    11581 ccattaggac agacaatcac agcctgatag gcttgacgat gaaaatctct tccctgctgc
    11641 tttaaatagc ctccaaaatg aagaacaaaa taagcaattt cactatctgg tataggacta
    11701 cccagctcct tggctaaagg ctccagagac tgctttacca agtcaaaaag ctcagaataa
    11761 ctatccttaa tccgcaaggt ataatcatta tcacttggca aaccatagcg caaacggtaa
    11821 taggctggaa tcaaatgcct tttcaaattc tccttgagct gatctgcctg actaaagctt
    11881 agtaaagcaa ccccctgcat ttgatcaaca atcgcaacgg ttagtgattc aaagaaatca
    11941 tcaccaacag taccctcacc ctcaaagcag cccgctaaca gcaattgaaa ataggcctca
    12001 tcagcttcaa atagctgata cttaagagac aattgctgca ttatttctgc caccaaaagg
    12061 gccgttagct gatccagctg ctcagaaacc actacctgtc tttgcttgac cctatcaacc
    12121 cgtctttggt aacgacataa aataaagatg acagcgtaca aacagacctg cagacgatca
    12181 aggatcggag acatctgaaa ggtctgataa aaatggctca cacgtttttc aagcgcttca
    12241 aacgacacct gatagtgcca agaagccaaa atatagtcca aggcccacaa gccaatagga
    12301 gatttaagca aagtagcaat cattactaaa gccaaccggt gcttattaat ctcatcacca
    12361 actaagatat agccgcttgc tctggtatac tttaattcca agtcaacatc tgccagcttc
    12421 tgccgcaagg ccttaatatc tgtcaaggct gtgttcttgc tgacctttaa aaagtcctga
    12481 taatgactat ttgaaacaaa atccctgcgg caaaaggtat acagatagat aagattgatc
    12541 cgctctgcct gagaaagata aacctgctca gcattaatca acgtaaacaa atgatctgac
    12601 tcagccttaa gctgctgact gatccgatag ccagaccttg ttgcatctag ctctgagagc
    12661 tcatgctgag ccaaaaactc attcagctca tcaatacggt ccttaatctc tctaatggtg
    12721 aattttgtct taacactcag ctcgtaaagt gataagtctt gataagtcat caacgtcatc
    12781 aaaatgacaa ctgctttgct atcaaccatt tgatttcctt tctaaattca ttctatcgaa
    12841 aacggttaca ataaactagt ccccattggg cacaatttct tatccaacat catcaacagc
    12901 ccttgggctc aagatgccaa tctaaacagg ctaccagctc ctcctaacta tcaataaaga
    12961 gcaaacaagc ccatctctgc cgctaagcaa ttgtccccat gatttcctaa gtccaagcca
    13021 aagctaaagc tctttggagt aataaccgtc aaaaatgttc caaataatca aaaaaactga
    13081 ttgacctcat cagcatgtga taactctaga tataagccta aaacaagatt acagacttaa
    13141 tagttaactg gtaatctttt attataccac gaaaacggtt accaaaaaag acttgtgttt
    13201 tattatttta ataatataat gaaactataa gatatcttat taaatgacaa ataactacca
    13261 tcttggttag aaaggagtaa agctaattaa cccttagtag atcaccatcg ttttcagaaa
    13321 ggaaattcaa aatgaaaaaa gtaaaacaat tgatcatcgc aatgatagcg tccttattac
    13381 tcattgctaa cactgtacct tccattgtat atgctagtga agtgactaaa attcaacagg
    13441 aagaaaaagt aattgaagaa aaattatcac aacctctaga aatttcaaaa agtgagttag
    13501 atacattaat ccaagagaaa aaagctcttt atccaaattt aacagaacaa gaaatgcgtg
    13561 aaattgcgta taaagccatg agtccataca cttttagagc tagtgtatgg gacgggcaag
    13621 gagtaacctt agatgaattc gcttgggctt ttgatgttat tgtaggcggg ttaattagtg
    13681 gatatgcaac catcggaaag tacgttgcca aacatggagt agctgccgct cgagctgtac
    13741 ttagccgagc tgcaaaagct gcagctcaac gacttggtgt actaaccgga tttatttccg
    13801 gtttacttag agctgcattc tcagtaataa acatttacta taatgtcgga tatgccctag
    13861 cacaatatgt cgatgctcga gattatcacc caaataacgg tcgtataaat gcgtgggctt
    13921 aagaactata tttgttattt tattattgta atgtcagttt atacagcaat agcatattgt
    13981 ttcaatcgct tatccttatc atttactcca aaactagttt tctattcggc cataaccacc
    14041 tatacttttt acataacaaa aaataaagac tga
//
LOCUS       DARYXS010000050        14055 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.051, whole genome shotgun sequence.
ACCESSION   DARYXS010000050 DARYXS010000000
VERSION     DARYXS010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14055
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.051"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(64..504)
                     /gene="rplO"
                     /locus_tag="TV193_001229"
     CDS             complement(64..504)
                     /gene="rplO"
                     /locus_tag="TV193_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEL1513423.1"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            complement(706..888)
                     /gene="rpmD"
                     /locus_tag="TV193_001230"
     CDS             complement(706..888)
                     /gene="rpmD"
                     /locus_tag="TV193_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEL1513424.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            complement(903..1397)
                     /gene="rpsE"
                     /locus_tag="TV193_001231"
     CDS             complement(903..1397)
                     /gene="rpsE"
                     /locus_tag="TV193_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEL1513425.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            complement(1416..1772)
                     /gene="rplR"
                     /locus_tag="TV193_001232"
     CDS             complement(1416..1772)
                     /gene="rplR"
                     /locus_tag="TV193_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEL1513426.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(1875..2411)
                     /gene="rplF"
                     /locus_tag="TV193_001233"
     CDS             complement(1875..2411)
                     /gene="rplF"
                     /locus_tag="TV193_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEL1513427.1"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTSRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            complement(2733..3131)
                     /gene="rpsH"
                     /locus_tag="TV193_001234"
     CDS             complement(2733..3131)
                     /gene="rpsH"
                     /locus_tag="TV193_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEL1513428.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(3464..3649)
                     /locus_tag="TV193_001235"
     CDS             complement(3464..3649)
                     /locus_tag="TV193_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEL1513429.1"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            complement(3665..4207)
                     /gene="rplE"
                     /locus_tag="TV193_001236"
     CDS             complement(3665..4207)
                     /gene="rplE"
                     /locus_tag="TV193_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEL1513430.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            complement(4231..4536)
                     /gene="rplX"
                     /locus_tag="TV193_001237"
     CDS             complement(4231..4536)
                     /gene="rplX"
                     /locus_tag="TV193_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEL1513431.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(4620..4988)
                     /gene="rplN"
                     /locus_tag="TV193_001238"
     CDS             complement(4620..4988)
                     /gene="rplN"
                     /locus_tag="TV193_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEL1513432.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            complement(5013..5276)
                     /gene="rpsQ"
                     /locus_tag="TV193_001239"
     CDS             complement(5013..5276)
                     /gene="rpsQ"
                     /locus_tag="TV193_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEL1513433.1"
                     /translation="MMERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSK
                     KYKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            complement(5301..5507)
                     /locus_tag="TV193_001240"
     CDS             complement(5301..5507)
                     /locus_tag="TV193_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEL1513434.1"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            complement(5517..5930)
                     /gene="rplP"
                     /locus_tag="TV193_001241"
     CDS             complement(5517..5930)
                     /gene="rplP"
                     /locus_tag="TV193_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEL1513435.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(5934..6587)
                     /gene="rpsC"
                     /locus_tag="TV193_001242"
     CDS             complement(5934..6587)
                     /gene="rpsC"
                     /locus_tag="TV193_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEL1513436.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(6600..6944)
                     /gene="rplV"
                     /locus_tag="TV193_001243"
     CDS             complement(6600..6944)
                     /gene="rplV"
                     /locus_tag="TV193_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEL1513437.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            complement(6960..7238)
                     /gene="rpsS"
                     /locus_tag="TV193_001244"
     CDS             complement(6960..7238)
                     /gene="rpsS"
                     /locus_tag="TV193_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEL1513438.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            complement(7350..8183)
                     /gene="rplB"
                     /locus_tag="TV193_001245"
     CDS             complement(7350..8183)
                     /gene="rplB"
                     /locus_tag="TV193_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEL1513439.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLVNIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLLVRRRNE
                     K"
     gene            complement(8201..8497)
                     /locus_tag="TV193_001246"
     CDS             complement(8201..8497)
                     /locus_tag="TV193_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEL1513440.1"
                     /translation="MNLYDVIKKPVITEKSMYALEEGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAVEAE"
     gene            complement(8497..9120)
                     /gene="rplD"
                     /locus_tag="TV193_001247"
     CDS             complement(8497..9120)
                     /gene="rplD"
                     /locus_tag="TV193_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEL1513441.1"
                     /translation="MANVKLFDQTGKEVSTVELNDDIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            complement(9145..9771)
                     /gene="rplC"
                     /locus_tag="TV193_001248"
     CDS             complement(9145..9771)
                     /gene="rplC"
                     /locus_tag="TV193_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEL1513442.1"
                     /translation="MTKGILGEKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVSPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            complement(10069..10377)
                     /gene="rpsJ"
                     /locus_tag="TV193_001249"
     CDS             complement(10069..10377)
                     /gene="rpsJ"
                     /locus_tag="TV193_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEL1513443.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPFPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(10757..12058)
                     /locus_tag="TV193_001250"
     CDS             complement(10757..12058)
                     /locus_tag="TV193_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL1513444.1"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGMIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKEIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLFTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYIWGFGVIGIAWSTVASRLIGVVILCHFLPIKEIIKRFANPL
                     DKEIFSLSLPAAGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMS
                     TATVILVANQLGSGKGATIAKTVKETFLLATLMMLVMGLITYLLGPNLLPLFTADAKA
                     QQAGMVVLVFSLLGVPATAGTLVYTAAWQGIGQAKLPFYATTIGMWLVRISLGYFIGV
                     TLNYGVIGVWLATILDNATRWLILAVAFKKQQRQLFSDCHS"
     gene            complement(12098..13582)
                     /locus_tag="TV193_001251"
     CDS             complement(12098..13582)
                     /locus_tag="TV193_001251"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEL1513445.1"
                     /translation="MPMMYQSTRNAANKVTASQAILSGLADDGGLFTPTSMPVLDLDF
                     EELKTKSYQEVAKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLE
                     LFHGSTIAFKDMALSILPYLLTTAAKKQGVERKIAILTATSGDTGKAAMAGFVDVPGT
                     DIIVFYPKSGVSRIQELQMITQAGHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAA
                     QQIQLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLEAGETINIVVPTGNFGNLLVAY
                     YAKEIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVF
                     YLLGNDAQKTAVLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDH
                     YVLDPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEAL
                     EQLADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
BASE COUNT         3977 a         3139 c         2613 g         4326 t
ORIGIN      
        1 ctaacattct ttatcttcaa tgcgtctttg agtattttta agaacataat gagtatcccc
       61 tcattagatg acttctattg aaccaccctt agcagtaatg gctgcttcag cagattttga
      121 aaatttcgct gctttaacag tcaatttttt agtcaattcg ccgttaccaa gaattttaac
      181 gcctgacttt tcagcacgaa cgattccagc ttccttaaga acaactggag ttacttctgt
      241 gccatcttca aaagcgttta attgatcaag gttaacaaga gcatactctt tagtgttgat
      301 atttgtaaat ccacgctttg gaatacgacg gaacaagggt gtttgtccac cttcaaagcc
      361 tagacgtacg ccaccaccac tacgagcctt ttgacctttt tgaccgcgtc cagatgtttt
      421 accattgcct gatgaagtac cgcgtccaac acgattgcgg actttacgag agcctttggc
      481 aggcttcaat tcatgaagtt tcattttttc tccttttttt gtaaaatgct agcgcctcta
      541 tgaagggaaa ggactctcca tagaaactcg cctatacatg atcaagctat gtcatagcct
      601 gatgctatat gcaccaaccg accactgctt gtcattcaaa ggaataactc acaaaagccg
      661 gttctgcatg ctaatgcaag aaatcagaga tttctagcta actctttatt tgacatcttc
      721 aactgtcacc aagtgagaaa ttgctgtcac cataccacga atagcagcat tatcttcctt
      781 gataactgaa gagtttaatt taccaagtcc aagggcaaca accgttttac gttgttctgg
      841 cttacgtccg attggagact tagtcaaagt aattttaatt tgagccatga tgatcccctt
      901 tcttaagcta agtcagaaac tgagatgcca cgaagtgcgg caacttcttc tgcacgttta
      961 agctgtttta atccttcaac agttgcacga acgatgttga ttggagtgtt tgaaccaaga
     1021 gattttgaag taatatcagc aatacctgct aattcgatga cggcacgtac cgcaccacca
     1081 gcagcaactc cagaaccttc tacagctggc ttcaacaata ctttagctcc accaaagtta
     1141 gtgtaaacct cgtgaggaat tgttgtgcca accattggca cttcaatcat gctcttttta
     1201 gcagcttcaa ctgccttgcg aatagcttct ggtacttcct gagctttacc agtaccgaat
     1261 ccaacatgtc cgtttccatc accaacaact acaagagctg caaaacgaag acgacgtcca
     1321 cctttaacaa cttttgtaac gcggttaata gcaacaacgc gttcttcaag ttcaactgca
     1381 ttatctttaa atgccattat tttgtgtcct ccctattaga atttcaatcc gttttcacga
     1441 gctgcatcag ccaaagcttt aacacgtcca tgatagagat atccaccgcg gtcaaacacc
     1501 acttcagaaa tacctttagc caccgcacgt tcagcaacaa gtttgccgac tacaacagct
     1561 tgttcagttt ttgttccttt agaaacttct ttatcaagag ttgatgcact tgcgagcgtt
     1621 acacccgcta cgtcatcaat aacttgagcg tagatgcctg tattagaacg gaatacgttc
     1681 aaacgtgggc gatcagcagt tccagagagt ttaccgcgaa cgcgacgatg gcgtttttgg
     1741 cggattttgt ttttatctgg tttcgaaatc acaattttca cctcttaata tttaagtttg
     1801 tctttccgac aaattatcaa ttgagcttgt agagcatgac ataagcaagc ctatgccata
     1861 ttccactaag aacattattt acctgtttta ccttctttaa ggcgtacata ctcaccaacg
     1921 taacgaatac ctttaccttt gtaaggctct ggtgaacgta ggctacgaat gtaagcggca
     1981 gtttgaccaa caacttcttt gttgataccc tcaactgaaa ttgatgttgg attagctaca
     2041 gtaaatgtaa tcccttctgg agcttccacc tcatcttggt gagatttacc tactgaaaga
     2101 acaagcttag agccttgaag ctgtgcacga tatccgacac ccttcatttc aagctctttt
     2161 ttgaaacctt ctgaaactcc aacaaccatg ttattcaagt ttgcacgact tgtaccatga
     2221 attgttttca tttcttttga gtcgtcagga cgtacaagag tcatttcgtt tccttcgact
     2281 ttgatttcaa tatttttgtt aaactcacga gtgagctctc ctttaggccc ctttacagta
     2341 acaacattgt cgttgttaat gatttcaacg cctgcaggga taataataac cttattacca
     2401 atacgtgaca tattaatttt ttctcctgtt aaattatcag gccgcttacg cgacgagttt
     2461 tcacggggtg aactaagata cttagggcgt aaaaggcaaa gtgaaaatag gaaacattac
     2521 tatgaaacca aggtttctag aaaaatttat ctttttcaca cagactttag cccatgttca
     2581 attagttctt ttacgtttgc tatgttgata gtgttcatca tttgagcaca gccgacgaac
     2641 tgccatctaa aatagacaaa ctattttgtt tgcaagcaag ccacaataat tttctaattt
     2701 tagattgttc gttacggctt ttgtctctta aattaccaaa cgtatgcgat aacttctcca
     2761 ccaacgttct tttgacgagc ttctttatca gtcaaaagac cttctgaagt tgaaataatt
     2821 gcaattccta gtccattaag aacctttgga acatcctcac gcttagaata aatacgaaga
     2881 cctggttttg aaacacgttt taagttagtg atgacacgtt caccattttg accgtactta
     2941 agaaatacgc gaataattcc ttgtttgcca tcttcaataa cttcaacgtt tttgataaag
     3001 ccttcacgct taaggatttc tgcaatccct tttttaatat ttgatgcagg tacttctaac
     3061 acttcatgct ttacttgatt agcattacga atacgtgtca aaaagtctgc aattgggtca
     3121 gtcataacca ttttattatt ctcctcttac tagtagtttg caagctgcac ttgctagtta
     3181 atcgatgata caaagggcgc taaaagccaa agtcaaaata ggaaacttcc gcaggaggga
     3241 aaacctccaa ggaatgttta tctttttgac accggctttc gcccgtgttc aaattgacac
     3301 tttgcctttg catcgaatca gacataatat ctgatagtat tatttgttca tttgaactga
     3361 gttcaagcta ctacctttag gtgcaaaatt tcctagagta tttagactct tcgtcaattt
     3421 tcctattttt gcttaggtag cttaacgctc tcacatcatc attttaccaa gacgctttaa
     3481 caacacctgg gatttggcct ttgtaagcca actcgcggaa gcaaacgcgg caaagcttaa
     3541 acttgcggta aacagaatgt ggacgtccac atttttcaca acgagtgtaa gcttgtgtag
     3601 aatacttcgc aggacgtttg tttttagcaa tcatagattt tttagccaat ttagttaccc
     3661 cctattattt tgcaaaaggc attccaagac ctttaagcaa ttcacgtgat tcttcgtcag
     3721 tgttagcagt tgttacgata acaatatcaa gaccacgcac tttatcaaca tcatcaaagt
     3781 tgatttctgg gaagataagc tgttctttca caccaagagt gtagttacca cgaccatcaa
     3841 atgattttgt tggaacacca tggaagtcac gaacacgagg aagtgaaacg ctaactagct
     3901 tgtctaggaa ttcgtacatg cgttcgccac gaagtgtcac cttcgcaccg atagcaacac
     3961 cttcacgaag acggaagcca gcgattgatt tcttagcttt agtaataagt ggtttttgac
     4021 ctgagataag cgccaattct gcagcagctt tttcaaggtt tttagcgttt gatacagcgt
     4081 cacccacacc catgttaaga acgattttct caacctttgg cacagccata actgatgtgt
     4141 aattaaactt ctctgtcaac gcaggaatta cttcgttagt atatttttct tttaaacgat
     4201 ttgccattat gcttctcctt tccttcgtga ttaatcaagc acttcgcctg attttttgtt
     4261 gtaacgaact tttttgccgt ctacaaactt gtaaccaacg cgtccagcaa caccattttt
     4321 atcaagaact tgaacgtttg atgcatggat tggtgcttct ttttcaacga tagcaccttg
     4381 aggattttcg ctgtttggtt tttgatgctt tttgatgatg gctacgcctt caacaataac
     4441 tttgtttact tttggaagtg ctttaagaac aacagcttca acacctttgt ccttaccagc
     4501 aataacgcga accttgtcgc ctttttttac aaacattatg ggtttctcct attattttct
     4561 tacgccccta tgggcaccct aggctagcct aggggactta gtttgtttaa tgattaaaat
     4621 taaagtactt ctggtgcaag tgatacgatc ttcatgtagc caccctcacg caattcacgt
     4681 gcaacaggcc caaagatacg agtcccacga ggagtcttgt catcacgaat aatgacagcc
     4741 gcattgtcat caaatttgat gtatgaaccg tctggacgac gagcaccact ctttgtacga
     4801 acaataacag ccttaacaac atcacccttt ttaactgctc caccaggagt agcttgtttt
     4861 acagatgcaa cgatgacgtc accgatgtta gcaaacttac gccctgaacc accaagaacc
     4921 ttgatagtca agatctcacg agcaccgcta ttatcagcaa ctttcaagcg agtttcttgt
     4981 tgaatcattt caattgtctc cttttagttt gattagataa taacagcttc ttccacgatt
     5041 tctacaagac ggaagcgttt tgtagctgaa agtggacgag tttccatgat acgaacgata
     5101 tcgccttctt tagcaaggtt cttttcgtca tgtgctttgt attttttaga atagttgata
     5161 cgtttaccat agactgggtg gttacgcttt gtttcaacta taacagtgat tgttttgtcc
     5221 atcttgtcag atacaacacg tccaacaagg gttttacgtt gattacgttc cattatttag
     5281 aatactcctt tcccaatcta ttatttcatt tcagattgca cagtctttac acgtgcaatt
     5341 tgttttttaa cttcgttcaa acgagcagtt tgatctagtt gacctgctgc agcttgaaaa
     5401 cgaaggtcga aaagttcttt tttgagttcg ttttctttct tagcaagctc ttcttgagac
     5461 aagccacgaa gctcagcaac aaactttttg atttcttcaa gtttcatgtc ttctccttat
     5521 tctgcttcac gttttacgaa tttacattta actggtagct tgtggctagc aagacgaagt
     5581 gcttcacgag cgatttcttc agaaacacca gcaacctcaa acataacctt gccacgctta
     5641 actggtgcta cccaaccttc aggtgcaccc ttaccagaac ccatacgaac cccgatagct
     5701 ttagctgtat aagatttgtg agggaagatt ttaatccaaa ctttaccacc acgcttcatg
     5761 taacgagtca tagcgatacg agcagcttcg atttggcggt tagtgatcca tgagctagta
     5821 gtagcttgaa gaccatattc accgaatgat acttcttttc caccttttgc ttcaccgcgc
     5881 atttttccac gaaactcacg acggtgttta acacgtttag gtactaacat ctgttatttg
     5941 cctcctttag tgtttttgcg agctggaaga acttcaccac gataaatcca aactttaaca
     6001 ccaagtttac cgtatgtagt atctgcttct tcccaagcat agtcaatatc tgcacgaagt
     6061 gtgtgaagag gaacagttcc ttctgagtag ccttcgctac gcgcgatatc tgcaccgttc
     6121 aagcgacctg aaacttgagt tttgattccc ttagctccag cacgcattgt acgttgaata
     6181 gcttgttttt gagcacgacg gaaagcaaca cgttgctcaa gctgacgagc aatgttttca
     6241 ccaacaaggt gggcatcaag atcaggctgt ttgatttcga tgatgttgat gtgtacttgt
     6301 tttccagtta atttgttaag ctgagcgcga agagcgtcaa catttgctcc acctttaccg
     6361 ataaccatac caggctttgc agtgtgaagt gaaacaataa ctttatttac agcacgctca
     6421 atttcaattg ttgaaactga agcctctgcc aattctttgt taatgaattt acggattgca
     6481 agatcttcat gaaggtaatc cgcgtattct ttttcagcat accattttgc atcccagtca
     6541 cgaatgattc cgacacgcat accaattgga tgtacttttt gacccacgat tttacctcct
     6601 tatttttctg atacaactac tgtaacgtga gttgttcgct tgttgattgg tgacgctgag
     6661 ccctttgcac gtggacggaa acgtttcatt gttggtcctt cgtttgcaaa tgtttcagat
     6721 actaccaagt tagctttttc caaaccaaag ttattttctg cgttagcaat tgctgagtta
     6781 agagttttct caataacacg agctgctttg tttggagtga attttaagat tgcgattgca
     6841 tcagcaactt tcttaccgcg gataagatca agtactaaac gtgttttacg aggtgaaaca
     6901 cgcactgtac gagccattgc tttagctgaa gtaatttctg ccattgtgtc ctcctcctat
     6961 taacgacgtg ttttcttgtc gtcagctgcg tgacccttgt aggtacgagt tggtgcaaat
     7021 tcaccaagct tgtgacctac catgtcttct tgaatgtaca caggtacatg cttgcggcca
     7081 tcataaactg cgattgtata tccgatgaaa cttgggaaaa tcgttgaacg acgtgaccaa
     7141 gttttgatta cttttttctt ttcgtcatta gcttgagctt caactttttt catcaaatgc
     7201 tcatcgacga aaggtccttt tttaagacta cgtcccattt tgtagttttc tcctttaaat
     7261 aatgtaccac agcggcttga gcatgagagc aagctcaaac tctaccgagc tggcggaatg
     7321 attgaataag cttatgctag atttgccgct tatttttcgt tacgacgacg aacaagaagc
     7381 ttgttagatt tagctttttt gttacgtgtt ttaagaccaa gcgctggttt accccaagga
     7441 gtagatggcg ctttacgtcc aactggtgct ttaccttcac caccaccatg tgggtgatcg
     7501 ttagggttca ttacagaacc acgaactgtt gggcggatac ctttccaacg gctacgtcct
     7561 gctttaccaa tgttaacaag tgattgttgc tcgttaccaa ctgtaccaac agttgcacga
     7621 catgttccaa gaatcatacg aacttcacct gattgaagac gaacaagaac gtatttgcct
     7681 tcttgaccaa gtacttgagc agaagctcca gcagcacgta caagctctcc acccttacca
     7741 ggcttaagct caatgttgtg aacaactgta ccaacaggaa tgtttactaa tggaagtgca
     7801 ttaccaacct taatatctgc atctggtcca gaaacaatac gttgacctac ttcaagaccc
     7861 ttaggagcga tgatgtaagc cttaactccg tcagtgtaat gtacaagtgc aatgtttgca
     7921 gtacggtttg gatcgtattc gattgtttta acaactgctt caacaccatc tttgttacgc
     7981 ttgaagtcaa tcaaacggta atggcgtttg tgtccaccac cttggtgacg aactgtaatg
     8041 cgaccattgt tgttacgacc agctttgttt ttaagagaaa caagcaatga tttctcaggt
     8101 gtgcttgttg tgatttcagc gaaatccaaa gaagtcatgt tacgacggcc atttgtcgtt
     8161 ggtttataaa ctttaatacc cacgttattt cctccttaga ttattcagct tcaactgcga
     8221 acaactcgat tgctttagaa tcagctgtaa gagtgatgat agccttttta gtttttgaag
     8281 taaaacctgt gtaacgacca acacgcttag cctttggttt aacgttaaca gtattgacgc
     8341 ttgcaacctt aactccgtca aatgcagctt caacagcttg cttgattaac agtttgtgcg
     8401 cacgtgtgtc aacttcaaat gtgtatttac cttcttcaag ggcatacatt gatttttcag
     8461 taataactgg ttttttgatt acgtcgtaca aattcattat gcaagaacct cctcaattgt
     8521 agagattgct tctttcgtta caagaagttt gtctgcgttt acgatatcaa gaacacttgc
     8581 agtcgctgct gttgccacag ctacgtttgg aaggttacgt gcagaaagtg ctgcaaattc
     8641 atttccttct tcaacaagaa caagtacttt tgtatcaatg ctaagagctg aaagcacctt
     8701 tgcaaattca gctgtttttg gtgctgcaaa tgaaaggctt tctacagcta caaatttatc
     8761 ttcagcaact tttgctgagt aaactgattt caaagcaagg cgacgaactt tttgtggaag
     8821 tttgtatcca tatgaacgtg gagttggtcc aaagacaaca ccaccaccac gccattgtgg
     8881 tgagcggata gaaccttgac gagcacgtcc agttcctttt tgacgccaag gtttacgtcc
     8941 accacctgat actgctgaac ggtttttaac cgcatgagta ccttggcgaa ggctagcacg
     9001 ttggctgatt acaacatcaa aaacaactga ttcgtttggt tcgataccaa agatatcatc
     9061 atttaattca actgtgctaa cttctttacc agtttggtca aatagtttta cgtttgccat
     9121 ttttaactgt tttctccttt cttattattt agcagcttta actgctgatt tgatggtgat
     9181 aagagatttc ttagcacctg gtacgttacc tttaataaga ataacgttct tttctgggat
     9241 aacttgtaca atttcaagat tttgaatagt tacacgattg ccacccatgc gtcctgccaa
     9301 atgtttgttt ttgaaaacgc ggtttggtga aacaggtccc atagaacctg gacgacgatg
     9361 gtaacgagaa ccatgggcca tcggaccacg tgattgacca tggcgtttga taacaccttg
     9421 gaagccttta ccttttgaag taccagttac atcaacaaca tccccagctg cgaagatatc
     9481 cacagtgatt tctgcaccta cttctaagcc ttcaatgttt ttgaattcac gaatgaagcg
     9541 cttaggagct gtgttagctt ttgctacatg gcctttggca ggtttgttgc tcaatacttc
     9601 acgtttatca tcaaaaccaa cttgaattgc ttcgtaaccg tctgtttcaa cagtcttaac
     9661 ttgaagcaca acgtttggag ttgcttcgat gacagtaaca gggataaatt caccggattc
     9721 agtgaagatt tgagtcattc ccactttttc ccctaagatt ccttttgtca tgagaaaata
     9781 attccttttc ttaataatat ttcaaaaagt ttttagtgag cgttttttat gctcaaaaaa
     9841 gttttttacg agcgtttttt atgctcaaag caagatactt aaggcgtcaa actcacagtg
     9901 aaaataggaa atctgacgaa gaaacttctg tttctaggaa gatttacacc tacaggtagc
     9961 cacatccgta atctaattaa aattagaacg gctgtgtctc tttttcacac agagtttagc
    10021 ctgtgttcaa ttagatatga actcgttcct cactcatgtt tcaaacaatt aaagcttgat
    10081 ttctacgttg acaccacttg gaaggtccaa tttcataagt gcatcaacag tcttttgcgt
    10141 tgggttcaca atatcaataa gacgtttgtg tgtacgcatt tcaaattgtt cgcgagaatc
    10201 tttatacttg tgagtcgcac gaataatggt gtaaagacta cgttcagttg gaaatggaac
    10261 tggtccagct actgttgcac ctgtacgagt tgcagtttca acgatttttt ctgccgctgt
    10321 atcaagtgta cggtgttcgt acgctttcaa gcggatacgg atttttttgt ttgccatctt
    10381 ttctcctctc gtctatttac gataataggc tagctcctcg agaaaaccga cacctgtcac
    10441 gtggcaatgc aaccgagcgt gtcgcaacct ctcgtatcac agctaaagct gtatttttac
    10501 agcaccataa tataatagca gaattaataa ggcattgcaa gcctttcagg ggattttttc
    10561 aaaaaaactt gccctaagaa agggcaagcc agattgaaga caaacctcag ctgttccagc
    10621 aatcctcttt gatcttccgc agataagaga agctattagc aaacagagcc tcaggcgtac
    10681 tttacattct gatgacagtg gctgactccc aaaaggaaag tcaccactca gaagtcttga
    10741 gacctaaata caaagtttag ctatgacagt ccgaaaaaag ctgcctttgc tgcttcttaa
    10801 aagccactgc aagaatgagc catctggtag cattgtccaa aatagtcgca agccaaacac
    10861 ctattactcc ataatttaag gttactccaa taaagtagcc caaagaaatc cgaaccagcc
    10921 acataccaat cgttgttgca taaaagggaa gcttagcttg tccgataccc tgccaggctg
    10981 ctgtataaac caaggtcccg gctgttgctg gtacccccaa aagagaaaag actaagacaa
    11041 ccataccagc ctgctgagcc ttggcatctg ctgtaaataa gggcagtaga ttagggccta
    11101 gcaaataagt gatcaagccc ataacaagca tcatcagggt ggctaacaaa aaggtttctt
    11161 ttacagtttt cgctattgta gcccctttgc cactgcccaa ctgattggca actaaaatga
    11221 ctgtcgcagt tgacatagca agtcccggca tataattaaa ttgagttaag gtttctccaa
    11281 tcgcattgcc tgccaaggcc tctgttccaa atctaacaat aatagtaaca atcagcacat
    11341 caccagctcg catcatgagc cgctcaccag ccgctggaag agagaggcta aagatctctt
    11401 tatctaaggg attagcaaaa cgtttaataa tttctttaat aggaagaaag tgacatagaa
    11461 taacaactcc aatgagacgt gatgcaacag ttgaccaagc aatccctatc actccaaatc
    11521 cccatatgta aagagaaagg gctgaaaata cagcgtttag caaattagtt aaaaggctga
    11581 ccttcatggg aatgctaggc tggcccttag cacgaataat cgcacctaag ctcgtgaaaa
    11641 gaccaagact aagaatcatt ccaccgacaa tggctaaata ctgcccacca agtctagcta
    11701 ccagactagc tgctcccaga aaggctaata tgcttttatg tcccactacg gacatcaagc
    11761 ctagaagaac tgatagagcc cccgttacta agatagcatt tgccatgtag tcgatttctt
    11821 tagaatggtt ttgctctcct acgcttctag caatgagact ggagactgca gcacctaatg
    11881 cgataaaaag ggcctgataa atcgtcagaa tattattagc aatcgcaatg cctgaaacag
    11941 ccgtaagtcc aatttgagca gccaaataat tgtctatcat tcccatcagc atttgcaata
    12001 tattttctgc cattgatgga agggccaagg acagtatctt ttttctattg tgagtcatta
    12061 tattcatatc aattgaaagg gagctccttt atgcctccta tactccaaga taagcctcta
    12121 ctgcctgctg catatctgct actgtcacta aaaggctatg acgaatgggc gcctcctgta
    12181 agccattgac cgcttgtggc acgactacac ctgatatatc agccaactgc tcaagcgcct
    12241 caaaatcact ggcaacctgc tgaccactaa tagcttccac aactacccgc ggaaacttat
    12301 aaggactagc agttgacgca acaatagtcg gtctagagtc acctgattgc tcccgataag
    12361 cacgataaac agctgaagct acagctgtat gtgggtcaag cacataatga tcagactcaa
    12421 atatcgtttt gatctcttta gcagtctctt gctctgttgc aaagcctgcc gcaaataaat
    12481 caaggataga ctgatctgca tcagctagct gatactgacc tgtttctgcc aagctcttca
    12541 ttaatactgc tgtcttttgg gcatcattgc ctagtaaata aaaaaccaag cgctctaaat
    12601 ttgaagacac caaaatatcc attgatggac tagtagtcac cttgaaggga cgctttttat
    12661 catacctacc actagcaaag aaatctgtca agacattgtt ttcattggaa gcacagatga
    12721 atttggcaac aggaagtcca atttctttgg cgtagtaggc aaccagtaga ttgccaaaat
    12781 ttcctgtcgg cactactatg ttaatcgtct ctccagcttc aagtcgctga tgccttacca
    12841 actgggcata agcataaata taatagacaa cctgaggaat caaacgacca atattcatcg
    12901 aattggccga agacagctgt atctgttgag ctgctagccg ctcacgcaaa tcagggtcat
    12961 taaacaggcg cttgacctct gtttgagcat catcaaaatt gccttcaatc gccacaacat
    13021 gggtattgtg accggcctgt gtgatcatct gcagctcctg aatcctgcta acgcctgact
    13081 taggataaaa gacaataata tccgttcccg gaacatcaac aaagcctgcc attgctgcct
    13141 taccagtatc acctgaggta gcggttaaaa tcgcaatttt tcgctccaca ccttgctttt
    13201 tagcagcagt tgtcaagaga taaggcaaaa tagatagagc catgtcctta aatgcgatgg
    13261 ttgagccatg aaatagctcc aaattatgat aatcctttaa cgtagctaga ggtgctatca
    13321 ctgctgtatc aaacttatca tcataggcag aagagataca agcatctaat tctgcttcag
    13381 tatagtcatc aaaaaaggct gataaaataa gcttggcaac ctcttgatag gacttggtct
    13441 ttagctcctc aaaatctaga tccagcactg gcatgcttgt aggagtaaac aagccaccat
    13501 catctgctag gccacttaaa atcgcttgac tagctgttac cttattagct gcatttcttg
    13561 ttgattggta catcattggc attgcttcac atcacctcat catttctttt gactattata
    13621 tcatattcca atcataagcc ttctaggatt tggagacagc cattttctgt gctaataacc
    13681 cagcagtctc aagccatcag cataaataaa ggactggtct agccagtcaa tttgttgctg
    13741 aacatgtctt taccttgagg cagcaaaaaa gcccttagaa aatcaattct aaggacttgt
    13801 tgttacttga gtctaggtag ttttagagct attgaagcta cttcagtcta atgaaaagtc
    13861 tcttatagga actttcccaa agtaatgttg acagcagtga ctgcctttcg aattccatat
    13921 ctaagttttg aggtctaaac tcaaagcttc taaactaaaa atcctccatt agaaaaaact
    13981 aagcaataat caagtgattt ttcttagtga aaggtgactt gactattgct taatttaaat
    14041 attaaatcat aaaat
//
LOCUS       DARYXS010000051        14029 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.052, whole genome shotgun sequence.
ACCESSION   DARYXS010000051 DARYXS010000000
VERSION     DARYXS010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14029
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.052"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..165
                     /locus_tag="TV193_001252"
     CDS             <1..165
                     /locus_tag="TV193_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513446.1"
                     /translation="VTYDSLVGQTRRHFDDKVAQARGLATKFKTVKEQLEEGIERTIA
                     TDQKLGGDFS"
     gene            162..554
                     /locus_tag="TV193_001253"
     CDS             162..554
                     /locus_tag="TV193_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513447.1"
                     /translation="MTALEKIRAAIRQKEEELEELQEHYHQERLQMAAAHDELRGNYN
                     QLQELYASTYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            573..857
                     /locus_tag="TV193_001254"
     CDS             573..857
                     /locus_tag="TV193_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513448.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGCLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALEQAIKTQNRGYSSLM"
     gene            complement(1056..1304)
                     /locus_tag="TV193_001255"
     CDS             complement(1056..1304)
                     /locus_tag="TV193_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEL1513449.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAQSKGLIHKNKASRDKARLAAKLS"
     gene            complement(1358..2278)
                     /locus_tag="TV193_001256"
     CDS             complement(1358..2278)
                     /locus_tag="TV193_001256"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEL1513450.1"
                     /translation="MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDI
                     NDVVEVYLPLIHLIQVYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSR
                     LLQLLLARTHKTSTVELVTTDGFLYPNSTLIKNNMLNRKGFPESYNMELLLNFLDTVK
                     GGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSHHIEQWYLERFLSLLELAKHDPANYYTRYTSLPQNEAIAFAKKVWKTINLENL
                     EKFIEPTRNRAELILHKAADHKIDEIYLKK"
     gene            2512..3141
                     /locus_tag="TV193_001257"
     CDS             2512..3141
                     /locus_tag="TV193_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1513451.1"
                     /translation="MKKHRKKIGKHMTKMYYDENPDSAHDIHQLTVNLLGQSFTFLTD
                     SGVFSKRMVDFGSQVLLNTLDFQEGDRLLDLGCGYGPLGLSLAKAQGVEATLVDINHR
                     AVGLAKQNAESNQVEATIFQSNLYDGVTGTFEHIISNPPIRAGKKVVHEIIEKSIDFL
                     TKGGDLTVVIQKKQGAPSAKDKMEAVFGNVTILKREKGYYILRSIKERN"
     gene            3240..4517
                     /locus_tag="TV193_001258"
     CDS             3240..4517
                     /locus_tag="TV193_001258"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEL1513452.1"
                     /translation="MRAVDLIQKKRDGKELSTEEIQWLINGYANGTVPDYQMSAFAMA
                     IYFKGMSTRETRDLTMSMVETGEQIDLSAIAGIKTDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTLDKLESIKGFQIGRTQEEFIKQVQEIGLSVIGQSDKLVKA
                     DKLLYALRDVTATVDIVPLIASSVMSKKIAAGADSILLDVTVGDGAFMKTIEDAEKLS
                     RLMVDLGKEVGRQTVAVITDMSQPLGRAIGNRLEVLEAIDIMKGKGRKDITHFICELA
                     QIMLELAGAQHSLEDIHHHLVGGAALKKLEEMVVYQGGDLEDLYRPSQAAVQTEVFAS
                     EDGYITALPALEFGLFAMRLGAGRAVKTDSLDYETGIVFDKKVGDAVAKGERIAVVFS
                     QEALDEKMLTEFEKNVKIGAEHLEANEIIKIIS"
     gene            4531..5193
                     /gene="deoC"
                     /locus_tag="TV193_001259"
     CDS             4531..5193
                     /gene="deoC"
                     /locus_tag="TV193_001259"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEL1513453.1"
                     /translation="MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVA
                     YAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDY
                     QAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGG
                     ATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANG
                     GY"
     gene            5180..5569
                     /locus_tag="TV193_001260"
     CDS             5180..5569
                     /locus_tag="TV193_001260"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEL1513454.1"
                     /translation="MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGNNIE
                     NASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAP
                     VTLIAKDGRTMRTTVGELLPYSFTDLS"
     gene            5660..6712
                     /locus_tag="TV193_001261"
     CDS             5660..6712
                     /locus_tag="TV193_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEL1513455.1"
                     /translation="MNKKFIGVGLASVALLGLVGCGNRNASKGSGDAKTDLKVAVVTD
                     TGGVDDKSFNQSAWEGLQAWGKDNGLTKGSGFDYFQSTNESEYATNIDTAVSSGYEVV
                     YGIGFALKDAISKAADDNNKVQFVIIDDVIEGKDNVASVTFADNEAAYLAGIAAAMTT
                     KTKTVGFVGGMEGTVVTRFEKGFEAGVKSVDDSIKIKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQVAGGTGAGVFNEARTINEKRDEADKVWVIGVDRDQNEEGKYTSKDGKSS
                     NFVLASTIKGVGKAVQLINKQAADKKFPAGKTTVYGLKDGGVEIATTNLSKDVIKAIE
                     EAKEKIKSGDVKVPEK"
     gene            6839..8371
                     /locus_tag="TV193_001262"
     CDS             6839..8371
                     /locus_tag="TV193_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513456.1"
                     /translation="MAQHVIEMKEITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGNIVINGQPVVIDSPSKSARLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLKKASKDIKELSEKYGLAVDPTAKIADISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIQELMEIMRNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIQTVDVAGATSQDLAEMMVGRSVSFTTAKKAAEPKGVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSGLIQAITGLRKTRSGSITIKGQEVVHLSSRKITELS
                     VGHVPEDRHRDGLVLDLSLAENTALQTYYKEPLSKNGILNYNTINDYARRLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRNPDLLIVSQPTRGLDVGAIEYIHKRLIEERD
                     KGKAILVVSFELDEILNLSDRIAVIHDGKIQGIVLPQDTNKQELGILMAGGSIDKEES
                     HV"
     gene            8364..9428
                     /locus_tag="TV193_001263"
     CDS             8364..9428
                     /locus_tag="TV193_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513457.1"
                     /translation="MSKNAQKIAVPMISILLGFLLGAIVMFIFGYDPIWGYEGLFQVA
                     FGSIKNIGEIFRAMGPLILIALGFTVASRAGFFNVGLSGQALAGWIAAGWFALVNPNM
                     PRPLLILMTVLIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIIQRGY
                     PESVKQSIDSTIQVSDNASYQSQWLSDLTNNSRINIGIFFALIAIAVIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSLKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     IGFDGMAVSLLAANSPIGIFFSSFLFGVLSIGAPGMNIAGIPPELVKVVTASIIFFVG
                     AHYLIERYIIRPKKLVKGGK"
     gene            9430..10386
                     /locus_tag="TV193_001264"
     CDS             9430..10386
                     /locus_tag="TV193_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513458.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERAGVVNVGLEGI
                     MVMGGGSGIVFNLEFAHIFGKATPWLAVLVGGVVGLIFSLIHALATINFRADHIVSGT
                     VLNLLAPSLAIFLVKVMYGKGQTDNIQQSFGKFDFPILSKIPVLGDIFFRNTSLVGYL
                     AVAFSFLAWFVLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPV
                     LEKIPTVYLQIAPYLLTIIILAAFFGQAVAPKADGVNYIKSK"
     gene            complement(10424..11680)
                     /locus_tag="TV193_001265"
     CDS             complement(10424..11680)
                     /locus_tag="TV193_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEL1513459.1"
                     /translation="MEHLNNTTQLIGIKDKHITLTKAIQHDTHIEVIATLDYNPPKCK
                     LCAGKQIKYDFQKPSKIPFIEIGGFPSLIRLKKRRFQCKSCRKVTVSETTLVKKNCQI
                     SEIVRQKIAQLLLNRKALTHIASKLAISTSTVYRKLKQYHFREDYANLPEVLSWDEFS
                     YQKGKLAFIAQDFNTKKIITILDNRRQTTIRNHFFKYSKEARNKVKVVTVDMSGSYIP
                     LIKILFPKAKIVLDRFHIVQHINRALKQIRSDIMKPFDKKSLKYRALKYYWKLIQKDS
                     RKRSLKPFYSRTFRQTLTPRECLNKIFSLVPELNSYYDLYQLLLFHLQEKNAKHFFGL
                     IHDTLPHLNQTFKTALNTFSRYQDYITNAIQLPYSNAKLEATNKLIKDIKRNAFGFRN
                     FDNFKKRIYLALNITKEKTTFVFSRA"
     gene            complement(12200..13915)
                     /locus_tag="TV193_001266"
     CDS             complement(12200..13915)
                     /locus_tag="TV193_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1513460.1"
                     /translation="MTYTENYQKWLDIPDLPAYLRDELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIFVVRQATEGLAALVESKGEAAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMPPADADALTDYIRAIDNPFAIRLADLEKAKANGLIEVIGEAVDLAYLEEVKKVNI
                     NQDLINDYGRDMKIVYTPLHGTGEMLARRALAQAGFKSVQVVEVQAKPDPDFSTVKSP
                     NPESQEAFTLAEELGRQVDADVLVATDPDADRLGVEIRQADGSYRNLSGNQIGALIAK
                     YILEAHQQAGTLPNNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNYTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDDIYKE
                     YGYFAEKTISVTLSGVDGAAEIKQIMDKFRKHAPAQFNHTDIVLTEDFLSQTATHKAG
                     QTQLTTPPSNVLKYTLADDSWFAVRPSGTEPKIKFYIATVGDTLALAEEKIANIESEI
                     NAFVS"
BASE COUNT         4038 a         2515 c         3281 g         4195 t
ORIGIN      
        1 gtgacctatg acagccttgt cggtcagacc aggaggcact ttgatgacaa ggtcgctcag
       61 gccagaggac tggccactaa gttcaagacc gtaaaggagc agctagagga ggggatcgaa
      121 aggacaatcg ctactgacca aaagctagga ggcgactttt catgacagca ttagagaaga
      181 tcagagctgc tatccgtcaa aaggaagagg agctagagga gctgcaggag cactatcatc
      241 aagagcggct ccaaatggca gcagcccatg acgagttaag aggcaactat aaccagctgc
      301 aagagctcta tgcctctacc tatcaggccg ttagcagcta cctcagacat tatgatgcta
      361 gcctgataac agaccaatat accgttctaa cgaggctgat tgatgactat cagcaccgaa
      421 cagagcagtg ctatcacgag caaggtcgca agatgtcgca gcaggaggaa gcaattgacc
      481 atcactatcg cagccagcga caggctatag agaaggacat cacagcgctg aggcgtcagt
      541 ggcgtgaagg ttaaggaaaa ggagataaga agatgattgc tatagagatg atcttaaccg
      601 gacaagagcc gatcaggact ttaaagaaag agctggatag gagattagtt cagtccatat
      661 gtgccccctt gaccttaggt tgccttcatg cccttcaaag gcgctatgac agtgaggtat
      721 ctcggattgc cacagacacc gcagatcata ttcagaccat tgtcaatcag ctagatagca
      781 gcattagagg gcaaggcagg acagcactag agcaagcgat caagacgcag aacaggggct
      841 atagcagcct gatgtgagac aggaaggact tactgtccta ccagctacag tcactacact
      901 gctagagctt gcggtgtgag cagcagtaag aggcaaaggc gttaccccag agggattgat
      961 ggatcaccat cactagtttg gagccattag ctgtgccaaa ggttttctaa agccaaaaag
     1021 aaaaaactcc gattggagtt ttcattggtt atgtattagc taagctttgc agcaagacgt
     1081 gctttatcgc ggcttgcttt atttttatga atcaaacctt ttgattgggc tttatcaatg
     1141 cttgaagaag cagcgcggaa aagctcttca gatgggttag cttcaaatgc cttgatagca
     1201 gtacgcatag ctgatttttg tgctgaattt ttttcgtttg ctttaacgtt aagctcagcg
     1261 cgtttaatag ctgatttaat atttgccaat gttttcacct ccaaattaat ctaactacac
     1321 cattatatag aaaatatagg tgtttggcaa gcacttatca ctttttgaga taaatttcat
     1381 caattttatg gtctgcagct ttatgaagaa tgagctcagc tcgattgcgt gtaggctcaa
     1441 taaacttttc cagattttct aggttaattg ttttccagac tttttttgca aaggcaatgg
     1501 cttcattttg tggcaatgag gtatatctag tgtaatagtt agccggatca tgcttagcca
     1561 gctctaaaag gcttaagaac cgttccaaat accattgctc aatatgatgg ctatctgcgt
     1621 caatataaat tgaaaaatca aaataatcac tcatatacaa tcgattattc tgttgatttt
     1681 gaaaaacatt aatcccttcg atgatgagga agtcaggatt ggtaaaggtt tgctgctgat
     1741 caggaacgat atcataaatc tcatgcgagt aaacaggggc tgatgcggtt tgtcctccct
     1801 tgacagtatc cagaaagttt aacaatagct ccatattata ggattctggg aagccctttc
     1861 gattcagcat attgtttttg atcagtgtgc tattagggta caaaaaacca tctgttgtga
     1921 ccaactcaac agtgctggtc ttgtgtgtgc gcgccaaaag aagctgcaat aacctgctag
     1981 ttgtggactt accgacggca actgagccag aaatcccaat aataaagggt ctttgctgaa
     2041 tatctttttt tagaaagagg cttttagaaa aagacaggtt ttcttgagcg attttataga
     2101 cttgaatgag atgaatcaag ggaaggtaaa cctcaacaac gtcgttgata tcaatattat
     2161 cattcaaact ggtgatgcta gtaagctcct cttgagtcaa taagggcttg cttttttgat
     2221 gtaattgctt ccaggatttt ctggaaattt tttcaaaagt aataaattcg tttgacatag
     2281 ttactcctac taattggcag tgcttacatt ataacatgtc aataaaaaaa ttgaaaaatg
     2341 tttcgtctga aattcttaaa aaaacactga aaaaccctat aaaaatcgaa caattttagc
     2401 ctaacaattg gctaatataa agttaatcgg tcaatgttcg gaatatatgg ttcgataaac
     2461 gaaaaaccaa gaaaaacaaa cgtcttgtaa accatttcaa agtgtgatag aatgaaaaag
     2521 catcgaaaaa agataggaaa acacatgaca aaaatgtatt atgatgaaaa tccagatagt
     2581 gctcatgata tccatcaatt gacggtcaat ttgttaggac agtcctttac ttttttgaca
     2641 gattctggtg ttttctcaaa aagaatggtt gattttggaa gtcaggtcct gctcaacaca
     2701 ttagattttc aagaaggtga tcgtctgctt gacttgggct gcggctatgg gccgctagga
     2761 cttagcttgg caaaggctca aggtgttgag gcgactctag tagatattaa tcatcgcgct
     2821 gttggcttag ctaagcagaa tgctgagagt aatcaggttg aggcgaccat ttttcaatca
     2881 aacctctatg acggtgtgac agggacattt gagcacatca ttagtaaccc acctattagg
     2941 gcagggaaaa aagtggttca tgagattatt gaaaagagta ttgatttttt aactaaaggc
     3001 ggtgatttga cagtcgttat ccaaaagaag cagggagcac caagtgctaa agacaaaatg
     3061 gaggccgttt ttgggaatgt gactattctc aaaagagaaa agggttacta cattttaaga
     3121 agtattaagg aaaggaattg agctcaagtg taaaaagtgg tattaaaaag catagcggta
     3181 ttttagtaag agttgccttc taatatcact attttctcag agcttttggt atcttgttga
     3241 tgagagcagt tgatttaatc caaaaaaagc gtgatggtaa agagctatct accgaagaga
     3301 tccagtggct gattaatggt tatgccaatg gtactgtgcc agattatcaa atgtcggctt
     3361 ttgcaatggc gatctatttc aagggaatgt ctacacgaga aactcgcgat ttgaccatga
     3421 gtatggttga gacaggtgag cagattgatt tgtcagctat agctggtatc aagacggaca
     3481 agcactcaac aggtggtgtt ggtgataagg tgacactcat cttagctcct ctagttgcta
     3541 gctttggcgt tcctgtagcg aaaatgagtg gacgcggctt aggccacacc ggtggaacgc
     3601 ttgataagct agaatctatc aagggctttc agattggtcg gacccaagag gaatttatca
     3661 agcaggtaca agagatcgga ctttcagtta ttggacaatc agataagctt gtgaaggcag
     3721 ataagctgct ttatgctctt cgtgatgtga cggcaaccgt tgatattgtt cctttgattg
     3781 caagctctgt tatgagtaag aaaattgctg ctggcgctga tagtattttg ctagatgtta
     3841 ccgttggtga cggtgccttt atgaagacta ttgaagatgc tgagaagctg tctagactga
     3901 tggttgacct tggtaaggag gttgggcgtc agacagtggc tgtcattaca gatatgagtc
     3961 agcctcttgg tcgtgctatc ggtaatcgct tagaggtgct agaggcaatt gatatcatga
     4021 aaggcaaggg acgcaaggat attactcact ttatttgtga gctagctcag attatgctgg
     4081 agcttgctgg tgctcaacac tctcttgagg atattcacca tcatttggtt ggcggagcag
     4141 ccttaaaaaa attagaagag atggttgttt atcaaggagg tgatcttgag gacctttatc
     4201 gtccatcaca ggcggctgtt caaacagagg tttttgcgtc agaagatggt tacatcacag
     4261 cattgcctgc tcttgagttt ggattgtttg caatgaggct gggtgctggt agagcagtca
     4321 aaacagatag tctggattat gaaacaggga ttgtctttga caagaaggtt ggtgacgctg
     4381 tcgctaaggg agagcgcatt gcagttgtct tttcacagga agccctagac gaaaaaatgc
     4441 ttacagaatt tgaaaaaaat gttaaaatag gggcggaaca cctagaggct aacgaaatta
     4501 tcaaaatcat ttcctaagga ggagtataac atgaatatta acaagtatat tgaccacaca
     4561 ctactaaaag ctgacagcgt tcaatcgcag cttgaccaat taattgagga ggctaaagcc
     4621 tatgactttg ctagcgtttg cgtcaaccct tgctgggtag cctatgctgc aaaggcttta
     4681 aagggaacag atgttaaggt ttgtacagtt gttggttttc ctttaggtgc aactacctca
     4741 gcaacaaagg cctttgaaac aaaggacgct attgaaaatg gtgctgatga gattgatatg
     4801 gttatcaata ttggtctgtt aaagcagggt gactaccaag ctgttgaaga tgatatgcgt
     4861 gcagtggtag aggctagcgg agacaaatta gtcaaggtga ttatcgaggc ttgcctcttg
     4921 actgatgatg aaaaggttaa ggcttgtcag ttggcggtaa atgcaggtgt tgactttgtg
     4981 aagacctcta ctggtttttc aactggcggt gcaaccgttt ctgatgtcaa gctaatgcgt
     5041 caaacagttg gtccagacat tggcgtaaag gcagctggtg gtgctcgttc tctagaggac
     5101 gctttagctt ttgtcgaagc aggagctaca cgtattggaa cttctgcagg ggtaactatt
     5161 atgaaaggtg aagttgccaa tggaggctac tgatttagtt tcgttagcca ttgaagctag
     5221 taaaagggct tatgtgcctt actcacattt cccgatcgga gctgctttaa agacaaagga
     5281 cggaacaatc tatactggca ataatatcga gaatgccagc tttggcttga ccaattgtgg
     5341 ggagcgaaca gctattttta aggctgtttc tgagggacat cagcagcttt tagaaattgc
     5401 catttatgga gagactgatg agccaatctc tccttgtgga gcctgtcgtc aggtcatggc
     5461 agaatttttt gaagccactg ctccagtaac gctaattgct aaggacggtc gtaccatgcg
     5521 cacaactgtt ggcgagttac ttccttattc gtttacagat ttatcgtaat ctggcttaat
     5581 tttgttatct agccattagg ctttatattt actttcggca attggtttgc tagaaatatt
     5641 tttaggaggg ttcatattca tgaacaagaa atttattggt gttggtttag cttctgtagc
     5701 tttattaggt ttagttggtt gtggtaatcg taacgcttca aagggatctg gtgatgctaa
     5761 aacagatttg aaggtagcag tggttactga cactggtggt gttgatgata agtcatttaa
     5821 ccaatcagct tgggaaggct tgcaggcttg gggtaaggac aatggactaa caaagggttc
     5881 aggctttgat tacttccaat ctacaaacga gtctgaatat gcaactaaca ttgatacagc
     5941 agtttctagt ggttatgagg ttgtttatgg tatcggattt gccttgaagg atgcaatcag
     6001 taaggctgct gatgacaaca acaaagtaca atttgttatc attgatgatg ttatcgaagg
     6061 caaagacaat gttgctagcg taacatttgc tgataacgaa gctgcttacc ttgcaggtat
     6121 tgcggcagct atgactacaa aaacaaaaac agttggtttt gtaggtggta tggaaggaac
     6181 agttgttaca cgctttgaaa aaggctttga ggcaggcgtt aagtctgttg atgactcaat
     6241 caagatcaag gtggactacg ctggatcatt tggagatgcc gctaagggta agacaattgc
     6301 agcagcgcaa tacgcagcag gtgctgatgt tatctatcag gtagctggtg gaacaggtgc
     6361 gggtgtcttc aacgaagcaa gaacaattaa cgaaaaacgt gacgaagctg ataaggtttg
     6421 ggtaattggt gttgaccgcg accaaaacga agaaggtaaa tatacatcta aggatggcaa
     6481 atcatctaac tttgtacttg catctactat aaaaggtgtt ggtaaggctg ttcaattgat
     6541 caataagcag gcagcagata agaaattccc tgcaggtaaa acaactgttt atggtctgaa
     6601 ggacggtggt gttgagattg ccacaacaaa tctttctaaa gacgttatca aagccatcga
     6661 agaagcgaaa gaaaaaatta aatctggtga cgtaaaagtt cctgaaaagt agttactgga
     6721 aaagagcgac cttcgtcggt cgcccttttt agagtggaac accttttgct tcagtaaagg
     6781 ttgtgacaaa tggctggctt tactgaaaca aaagattaaa ttgaaaggaa ataatcctat
     6841 ggcacagcat gtcattgaaa tgaaagagat tacaaaaaaa tttggtgatt ttgttgcgaa
     6901 tgaccatatt aatttgaatg tcagaaaagg cgaaattcat gcattgttag gagagaatgg
     6961 tgcaggtaaa tcaacgttaa tgaatatgtt agctgggctt ttagagccaa ctagtggaaa
     7021 cattgtcatt aacggtcagc ctgttgttat tgactctcct tccaaatctg ctagattggg
     7081 tattggaatg gtacaccagc actttatgct agtagaagct tttacagttg ctgagaatat
     7141 cattttagga aatgaagttg tcaaaaacgg ttgtcttgat ttaaaaaagg ccagcaagga
     7201 cattaaagag ctttctgaga aatatggttt agctgttgat cctactgcca agattgctga
     7261 tatttctgta ggggcacagc agcgtgttga aatcttaaag accttatatc gtggtgcaga
     7321 tattcttatt tttgatgagc caacagctgt tttaacgcct gctgaaatac aagagctcat
     7381 ggaaatcatg cgtaaccttg ttaaggaagg caaatccatt attttgatta ctcataagct
     7441 ggacgaaatt agagcagttg ctgatagagt cactgttatt cgacgtggga aaagtattca
     7501 aacagtagat gtagcaggtg caacctctca ggacttggct gaaatgatgg ttgggcgttc
     7561 agtttccttt acaacagcta aaaaggcagc agagccaaaa ggggtggtgc tgtcgatcaa
     7621 gaatttagag gtcgatgaaa atcgtggaat cccagcagta aaggggcttt ctcttgacgt
     7681 tagagctggt gaaattgtgg ggattgcagg gattgatggt aatggtcagt cagggctgat
     7741 tcaggccatt acaggcttga gaaagactag atctggtagc attacaatca aaggtcagga
     7801 ggttgttcat ttaagctccc gtaaaatcac agagctatca gtggggcatg tgcctgagga
     7861 ccgtcataga gatggcttag tgctggacct ttccttggct gaaaatactg cccttcagac
     7921 ctattataaa gagccactaa gtaagaacgg tattttaaat tacaatacaa tcaatgatta
     7981 tgctcgtaga ctgatgaagg aatttgacgt tcgtggtgcc aatgaattgg ttccagctcg
     8041 tggattttct ggcggtaacc aacaaaaggc tatcattgca cgtgaggttg accgtaaccc
     8101 tgatttattg attgtcagtc agccaactcg cggcttggac gttggtgcta ttgagtacat
     8161 tcataagcgt ttgattgaag agcgtgacaa aggcaaggcc atcctcgttg ttagctttga
     8221 gcttgacgaa atcttgaatt tatctgaccg tattgcagtt attcatgacg gtaaaattca
     8281 aggcattgtg ttgcctcaag ataccaataa gcaagaattg ggaattttga tggctggtgg
     8341 ttccattgat aaggaggaga gtcatgtcta aaaatgcaca aaagattgct gtgccaatga
     8401 tttctatctt gttaggattc ttacttggcg ctattgtcat gtttatcttt ggctatgatc
     8461 caatttgggg ctatgagggc ctatttcagg tagcctttgg tagtatcaaa aatattggtg
     8521 aaatcttcag agcgatggga ccactaatcc tgattgcact tggttttacc gttgctagcc
     8581 gtgccggctt ctttaatgtc gggctgtcag gtcaagcttt ggctggttgg attgctgcgg
     8641 gctggtttgc tcttgtcaat cctaatatgc ctcgtccgct tttaattctg atgactgtct
     8701 tgattggtat ggttgccggc ggaattgctg gcgctattcc aggtattttg cgagcttatc
     8761 ttggtacaag tgaagttatt gttaccatta tgatgaatta tattattctg tatgtcggta
     8821 acgctatcat tcaaagaggc taccctgaaa gtgttaagca aagtattgat tcaaccatac
     8881 aggtcagtga taatgccagc tatcaaagtc aatggctgtc agatttaacc aataattctc
     8941 gtattaatat cggtatcttt tttgcgctta ttgcaattgc agttatttgg ttcttactaa
     9001 acaaaacaac cctcggattt gaaattcgtt cagtaggtct taatccacat gcttcagaat
     9061 atgcaggtat gtccttaaag cgtacgatta tcctatcaat gatcatttca ggtgctttag
     9121 caggcttggg aggagttgtt gaaggcttgg gaacctttga gaatgttttt gtacagggaa
     9181 gctctctagc aattggtttt gacggtatgg ctgttagctt gcttgctgcc aattcaccga
     9241 ttggtatctt cttctcatca ttcctatttg gggtgttgag cataggtgct cctggtatga
     9301 atatcgcagg aattccacca gaattggtaa aagtagtgac tgcctcaatt atcttctttg
     9361 taggtgctca ctaccttatc gaacgctata ttatcaggcc taaaaaacta gtaaagggag
     9421 gtaaataaga tgagtttagt tactattttt gctttattgg tttcatcaat gcttatctat
     9481 gctacacctc ttatttttac aagtattggt ggtaccttct cagaacgagc tggtgttgtc
     9541 aatgtcggcc ttgaaggcat tatggtcatg ggggggggtt caggcattgt ctttaatctt
     9601 gaatttgctc atatctttgg taaagctact ccctggcttg cagttttggt gggaggagtt
     9661 gttggattga tcttttcatt gatccatgcg cttgcaacga ttaactttag ggcagatcac
     9721 attgtcagtg gtacagtgct aaatctgctg gcaccatcgc ttgccatttt cttagttaag
     9781 gtgatgtacg gtaaggggca aactgataat atccagcaat cattcggtaa gtttgatttt
     9841 ccgattctct caaaaattcc agttcttgga gatatattct ttagaaatac tagcttagtt
     9901 gggtatttag ctgttgcctt ttctttccta gcttggtttg tgctttacaa aacaagattt
     9961 gggttgcgtt tgcgctctgt aggtgaacac cctcaagcag ctgatacact tggtattaac
    10021 gtttacctca tgaaatatta tggggttatg atctctggtt ttcttggggg tattggtgga
    10081 gctgtctatg cacaatccat ctctgttaac ttcgcagtga caaccatttt aggacctgga
    10141 tttattgccc ttgccgctat gatttttggt aagtggaatc cggtaggtgc tatgctatct
    10201 agcttgttct ttggattatc acaaagctta gcagttattg gggcacaatt accagtattg
    10261 gaaaaaatcc caacggttta ccttcaaatt gcgccatacc tattgaccat catcattttg
    10321 gctgctttct ttggacaagc agtggctcca aaggcagacg gtgttaatta catcaaatca
    10381 aaataaaaaa agctcaatgt caactgtagt gggtgactga tagctaagca cgagagaaga
    10441 cgaatgtcgt cttctctttt gtgatattca aagcgaggta gatacgtttt ttaaagttgt
    10501 caaagttccg aaatccgaaa gcattgcgct tgatatcttt gataagtttg ttagtggctt
    10561 ctaacttagc gttagaataa ggcagttgaa tggcattggt gatgtaatct tggtagcgac
    10621 taaaggtatt tagagctgtt ttaaaagtct gattaagatg tggtagtgtg tcatgaatta
    10681 aaccaaagaa atgcttggca ttcttttctt gcaggtgaaa aaggagcagc tggtacaggt
    10741 cataataaga gtttaactca ggcactagtg agaagatctt attgagacat tctctaggag
    10801 ttaaggtttg tctgaaggtg cgggaataga aaggcttaag agaccgtttt ctgctatcct
    10861 tttgaataag cttccagtag tacttaagag ctctatattt aagagacttc ttgtcaaatg
    10921 gtttcatgat gtcactacgt atttgcttga gagctctatt gatgtgctgg acaatgtgaa
    10981 aacgatcgag aacgatttta gccttaggaa atagaatttt aatgagagga atataacttc
    11041 cagacatatc gacagtgacg actttcacct tgtttctagc ctctttagag tacttaaaga
    11101 aatgatttcg gatggttgtt tgacgtctat tatcaagaat ggtaatgatt ttcttagtgt
    11161 taaaatcctg agcaatgaag gctaatttac ctttctgata agagaactca tcccaagaga
    11221 gaacttctgg caaattggcg taatcctctc ggaaatgata ctgcttaagc ttgcgataga
    11281 cggtagaagt ggagatagcg agcttagaag cgatatgggt gagagccttt ctgttgagta
    11341 aaagctgagc gattttctgt ctcactatct cagaaatttg gcaatttttc ttaaccaggg
    11401 tagtttcaga tacagtgact tttcgacagg atttgcattg aaaccttctt tttttcaaac
    11461 gaatgagact aggaaagcct ccaatttcga taaagggaat tttagagggc ttctggaagt
    11521 cgtatttgat ttgttttccc gcacacagtt tacatttagg agggttatag tctagtgtag
    11581 cgatgacttc aatatgagta tcatgctgga tagctttagt caaggtgata tgtttgtctt
    11641 tgattccaat gagttgtgtg gtattattga ggtgttccat aagatacctt ctaaatgata
    11701 gtttagtcgc ttttcatgat aagtcttatg ggactttttt gatactcaaa aagccctata
    11761 atctccacag tagccttacc cactacagaa attatagagc catcttagaa cactggactt
    11821 gttcgctttt taatgaatta aatttagtag atcctttaaa ggcatgctat caagcttttt
    11881 atccttgact tttgtttagc aagtgaagtg ttcacaaaag ctagctaaaa cactgagctg
    11941 acaatgtaga gaatggctcg ttttgacaag gttagagtgc tttttgctgt atggttttta
    12001 atccacgcac ctgaaaaaga aaggacagga cctgtgcgag cttacttgtg gttagtaggt
    12061 ttcaattcat gctcccaaaa aggaagcaac gcaactctga gaaaggtctt agaccacttt
    12121 cccagtttgc ctcacagcta atggtgtaaa acaaatagac caccctgtaa caggtggtca
    12181 tggttagata tcagctcatt taagagacaa aggcgttgat ttcagattca atattggcaa
    12241 ttttttcttc ggcaagcgca agggtgtcac caacagttgc gatataaaat ttaatttttg
    12301 gctctgttcc tgatggtctt acagcaaacc atgaatcatc agctagggta tattttaaga
    12361 cattgcttgg aggagtggtt agctgggttt gaccagcttt atgagttgcc gtctgactga
    12421 ggaaatcctc tgttaacaca atatcagtgt gattaaactg cgcaggggca tgcttgcgga
    12481 atttatccat aatctgtttg atttcagctg cgccatcaac accagacagt gtaacagaaa
    12541 tggttttttc tgcaaagtag ccgtattctt tgtaaatgtc atcaatacca tcagcaaggg
    12601 ttagtccacg agagcggtag taggcagcaa tctcagccac caatagcacc gcttgaatag
    12661 cgtccttatc acgtacaaat ggtttaatga gataaccaaa gctctcctca aagccaaaca
    12721 tataggtgta attgtgcttt tcttcaaatt cttgaatttt ttcagcaatg aacttgaagc
    12781 ctgttaagac attaaacatg gttgccccgt agctctctgc aattttagtc actaattcag
    12841 tagagacaat ggatttggca agagcggcat tgttaggtag ggttccagcc tgctgatgtg
    12901 cttctaaaat atacttagca attaaagcac caatttggtt gcctgatagg ttgcgatagc
    12961 tgccatctgc ctgccgaatt tcaaccccaa gacggtcagc atctggatca gtagcaacaa
    13021 gaacatcagc atcaacctga cgtccaagct cctcagcaag agtaaatgcc tcttgacttt
    13081 caggattagg agatttgacg gtagaaaaat ctggatctgg cttagcctgc acctcaacca
    13141 cctgaacgga cttaaagcct gcttgtgcca aggcacgacg tgctagcatt tcacctgttc
    13201 catgaagagg tgtatagaca attttcatgt cacgaccata gtcattgatg aggtcttggt
    13261 tgatattgac ctttttgacc tcttctaaat aagcaaggtc aacagcttca ccaataacct
    13321 cgatgagccc attagctttg gctttctcta aatcagcaag cctaatggca aaggggttat
    13381 caatcgcacg aatgtaatct gttagagcgt cggcgtcagc tggaggcatt tgaccgccgt
    13441 cagacccata aaccttatag ccgttgaatg gtgcagggtt gtgactggca gtaaccatga
    13501 taccggcaaa agcacccaaa tgtcgcacag caaaggaaag ctcaggtgtt ggccgaaggc
    13561 tttcaaaaac gtatgattta atgccatgag ctgctagtac ctgtgcagat tcaaaggcaa
    13621 attctggaga aaaatgacga gaatcatagg cgatagcgac accggccttc ttagcagctt
    13681 ctccctttga ctcaactaat gctgccaagc cctcagttgc ttggcgaaca acaaaaatat
    13741 tgatacgatt cgttccagcg ccaatatagc cacgcatacc agctgttcca aattcaagat
    13801 tggtgtagaa ggcatcttcc tttgtttttt cgtccatgct aagtaattca tctcttaaat
    13861 aggctggtag atctggaata tcaagccatt tttgatagtt ttctgtgtaa gtcatagtat
    13921 tctcctttat atttttaacc gctttcatta tatcatgttg aaaaggaaaa atcacttatt
    13981 ttctgtaata gcttccaatc attttttcac ataaggatca atttccttg
//
LOCUS       DARYXS010000052        13246 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.053, whole genome shotgun sequence.
ACCESSION   DARYXS010000052 DARYXS010000000
VERSION     DARYXS010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13246
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.053"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            304..1848
                     /locus_tag="TV193_001267"
     CDS             304..1848
                     /locus_tag="TV193_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1513461.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNASTNIYLFTFMFVTY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGILIDKTETKFGKYRPILIIGNIITAL
                     SLILLLGLSGVSENIRFPLFILVLIIHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAIMTTLLMTGGQFVVSSFLVPKFGNFTPAFFHVLIYGTIVISAILGLLAVLGIWSKD
                     RKEFFGLGENTQKTALKDYLKVIKGNQPLQVLSIAAALVKFAVQFFGDSVVMVILFGV
                     LFGNYALSGQFSLLFIVPGILINIAFSGIARKRGLRFSYIRALQIGLVGLLAFGIVLF
                     MGNKGDLSLSHINLYTILFTVTLIIARYASQAPASLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVIGAVLAGIGFSKTYPTIETPLTPSLKMALIALHVGIPF
                     VALLVALILMSFYKLDKEEMVRIQEKIQVMKASSDKERVQAIAKNVPLSDMDYVDVTK
                     YPVDKD"
     gene            1932..2960
                     /locus_tag="TV193_001268"
     CDS             1932..2960
                     /locus_tag="TV193_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1513462.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLKQATSLDCQFGGSELNVISSLA
                     QLGHQVSLISAIPDNDLGQMTKTFLFSRQINQEHIIEKGQRLGLYYYQKGFSLRASRV
                     TYDRCHSAFWESKRADYDLEHVFDEADWFHVSGITPALTSDLYELTYYLMTKARAEGL
                     TISFDLNFRASLWSSFQEARDLLSPLVQLADVCIGIEPLTLKGSGALDLKDQLGLNRP
                     YDDEALLKEVLARLADTYGVKCFAFTQREMDYTNEYLLKAYLYQNGSLYKTQKSGIQV
                     LDRVGTGDAFTAGLIHGLLSYKDEQATLDVAMASFKFKHTIEGDSNIMTQDDIDHLLA
                     KESHEIQR"
     gene            2981..4771
                     /gene="uidA"
                     /locus_tag="TV193_001269"
     CDS             2981..4771
                     /gene="uidA"
                     /locus_tag="TV193_001269"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEL1513463.1"
                     /translation="MLYPILTKTRKIYDLGGLWQFKLGDHNPQELLASDELMVVPTSF
                     NDVVVDKDKRNYIGDFWYERFVDVPDLAADEELVLRFGSVTHNATVYVNGQALGQHKG
                     GFTPFEVLVPETHYQDNQIKVSVCANNILDYTSLPVGNYSEETQEDGSIKKIVKENFD
                     FFNYAGIHRPVKLMVRPKCHISDITITSDLSEDMTSALVEVSVETSAAVDEVKVTIFD
                     EEHKLVAQAIDGKARLDKVRLWEVLDAYLYTAHVEIIVDGNVVDSYDEPFGIRSIAVE
                     KGQFLLNGKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKELGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEVPAVGLFQNFTASLDLSPKDNGTWSVMKTKEAHEQAIRELVK
                     RDKNHPSVVMWVVANEPASHEEGAHEYFEPLIALYKALDPQQRPVTLVNLLLATPDRD
                     KVMDLVDVISLNRYYAWYVDHGDLIKGEVGLRQELLEWQKKFPNKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCRFYEMSHRVFDEIPNLVGEQVWNFADFETNLMIFRIQGNHKG
                     LFSRNRQPKHVVGLFKERWNTIPHYNYKKK"
     gene            4813..5484
                     /locus_tag="TV193_001270"
     CDS             4813..5484
                     /locus_tag="TV193_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEL1513464.1"
                     /translation="MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRST
                     IREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALTAQHATPKEVEALEKLVVDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
                     SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPIAAHDAMLLHIMTVKR
                     TAFLS"
     gene            5667..6284
                     /gene="eda"
                     /locus_tag="TV193_001271"
     CDS             5667..6284
                     /gene="eda"
                     /locus_tag="TV193_001271"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1513465.1"
                     /translation="MLNRLKENYFFAIIRGKTVEDAIAIAKHAILGGIRNIEITYSTP
                     NASEVIRILSAEFEHDDAVIIGAGTVMTPDLAREAIAAGASFLVSPHFSREIAEVANQ
                     ASNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     IDNVKEWKNAGAVAVGIGSALASRVEAEGYDSVTRIAASFVSALD"
     gene            6312..7709
                     /gene="uxaC"
                     /locus_tag="TV193_001272"
     CDS             6312..7709
                     /gene="uxaC"
                     /locus_tag="TV193_001272"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEL1513466.1"
                     /translation="MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWS
                     VMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
                     LAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAM
                     EERIAYFAENGCKASDISFTEIVFEAAEPEQLDRLMTRVLEGYQPQPLEVKQWQTAVF
                     AELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTGLAINMNRLLDHL
                     VQRDSLPKMIWYNLNPSYNIAVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQ
                     MNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGK
                     MAQDIAYNNAIQYFN"
     gene            7971..9065
                     /locus_tag="TV193_001273"
     CDS             7971..9065
                     /locus_tag="TV193_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEL1513467.1"
                     /translation="MKMSFRWYGKHDPVSLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKRIVEAAGLEISVIESIPVHEDIKQGKPNRDELIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNYPLPDGSTSLAFLKADLADVDPVADDLNLPGWDFSYSKEEMKA
                     IIEHYRHHISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQK
                     AVERFLDLYDSPNNGITMCVGSYASDPQNDVIAMTEYALKRQRINFMHTRNVTAGDWG
                     FQETAHLSQAGDIDMNAIIKLLVDYDWQGPLRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKIPDFGITVKTVGDK"
     gene            9081..9920
                     /locus_tag="TV193_001274"
     CDS             9081..9920
                     /locus_tag="TV193_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1513468.1"
                     /translation="MSRVIEFKDKVVVITGAGGVLCGSMAKAFAKAGAKVALLDLNQE
                     AAQAFVDDIEAEGGIAKAYQANVLSKENLEAVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHDTSLPEDTKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRSLLF
                     TEDGQPTARAEKILKNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            10184..10987
                     /locus_tag="TV193_001275"
     CDS             10184..10987
                     /locus_tag="TV193_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1513469.1"
                     /translation="MTAKTEQFVFCVDSDGCAMDTMTYKHQLFFGPLAADYFAVADQA
                     SFLKEWDRINLYSRTRGVNRFVGLVMGLEYAGVTGIDALKQWVQHTASLSNQSLEAEL
                     LKRPSDDLQKALDWSNEVNRQIEAYKGEALAFLGALAALKALHQLGQVFVVSSANKEA
                     VQKEWQDQGLMTHVDGLYCQDRGKKEAVIAQLIDEGYVRERMMMIGDSPGDLAAAEQN
                     QITFFPILVGKEASSWQDLSHAAEAFTTGDLTELDVKSLTEAFWRNLDR"
     gene            11102..12892
                     /locus_tag="TV193_001276"
     CDS             11102..12892
                     /locus_tag="TV193_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEL1513470.1"
                     /translation="MTHLVDLRKKPYSLDEEAICWVEDTIAAMTLEEKIGQLFVNMGA
                     SRSEDYLTQVLEDYHIAAVRYNKGMASEIWDQNYILQTKSKIPMLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGLEASAVGCNASFAPIVDLTRNWRNPIIAN
                     RNWGVNVDQIIELSKEYMKGIMEYGIMPFAKHFPGDGIDERDHHLSFASNPMTKEEWL
                     SSFGRIYGELAEAGLPGIMAGHIHLPNVEKAMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLLLPTAIEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILSDERLHDALRRTLGLKAKLGLHRFEGHREDIMLPKDKAMVLINTPEAQAIADEVAD
                     KAITLVKNKQAGIFPVTPERYKRVLIVNVEGYKGGFGAMIAGQKKRASDIVKELLEAR
                     GHEVTVWESTEERIMQLPEEERAAAIANVYAQKQPISNITEHYDLILNLVDVNSGGTV
                     QRIIWPAAKGTPDQPFYVHEVPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     AKLAGESEFTGVSPVDAFCGLIDTQLWHSF"
BASE COUNT         3625 a         2449 c         3242 g         3930 t
ORIGIN      
        1 gttggtgggg tgacgatact gacctcaaag gggttggata agtattggta aaaggcttga
       61 gctctgtctt gtgcagggct cagttttttt gatgtcaatg agtaattgtc tgatgattat
      121 ttttaaagac accagaaatt atcagatgaa tttaatgatt aaaatcctaa ataagcttta
      181 ttttttaaaa ttaggcgaaa aaagtttaaa ttgtgttgac aaatcatcag atgaatagta
      241 agataagcat gtagaaataa aacgcttaca caataagcga atgataaaag ggggatttct
      301 ctgatggaga aaacaattga ccaaagggtt gaagaggtta cctataaccg cgctaaggtt
      361 tggcagcttg ttttatttgc tttaaacaat gcttcaacca atatctacct attcacattt
      421 atgtttgtga cctacttttc aacaggtgtt ctaggcttgg cagctatttt tgtcagccag
      481 atcatgggtt atattcgtat ttttgatggc tttattgatc ctgcgattgg tatcttgatt
      541 gataaaacag aaactaagtt tggtaagtat cgtccgatcc taatcatcgg aaatattatc
      601 acagccctat cacttattct gctgcttggt ctaagtggag ttagtgagaa cattcgtttt
      661 ccacttttta ttctggtttt gattatccat aagatcggct actctatgca gcaaaccatc
      721 actaaggctg gtcagacagc ccttactaat gatccgaagc agcgtccaat ctttaacatt
      781 gttgatgcca ttatgacaac cttgctgatg actggtggac agtttgttgt gtcaagcttc
      841 ttggttccaa aatttggtaa cttcacacca gccttcttcc acgtgttgat ttatggcacg
      901 attgttatct cagctatttt gggtctattg gcagtgcttg gtatttggag caaggacaga
      961 aaggaattct ttggtcttgg tgaaaatacg caaaagacag ctctgaagga ctatttgaag
     1021 gttatcaagg gcaaccagcc gctacaggtc ctatcaattg ccgcagcctt ggttaagttt
     1081 gctgttcaat tctttggtga ttcggttgtc atggttatct tgtttggtgt tttatttggt
     1141 aactatgctt tgtctggtca attctcattg ctgtttattg ttccggggat tttgattaat
     1201 attgcttttt caggtattgc tcgtaagaga ggtttgcgtt tctcatatat cagagctctt
     1261 cagattggct tggttggctt gttagccttt ggtattgtgc tctttatggg taataaaggg
     1321 gatctcagcc taagtcatat taacctttac actattttgt ttactgtgac actgattatt
     1381 gctcgctatg cctcacaagc gcctgctagc ttggtgctaa caatgggagc tgatatttca
     1441 gactacgaaa catcagaatc aggccgttat gtctcaggaa tgattggtac aatcttctcc
     1501 ttgactgact cgattgcatc atcatttgcg ccaatggtta ttggtgcagt gctggctggt
     1561 attggttttt caaagactta cccaacgatt gagacaccgc ttaccccaag tctaaagatg
     1621 gccttgattg cgctgcatgt cggtattcca tttgtagcct tactagtggc tttgattttg
     1681 atgtcattct acaagcttga caaagaggaa atggtgcgta ttcaagagaa gattcaagtg
     1741 atgaaagcaa gctctgataa ggaacgcgtg caggctatcg ctaaaaatgt accactgtca
     1801 gacatggact atgttgatgt gacaaaatat cctgttgata aggattaggt gctgggtcag
     1861 ctatttcttt gaggagtggc tgactttttt ataaaataat agagtagctt gatagtataa
     1921 ggaggaatgt tgtgaaaaaa gttgtatcct tgggtgaaat cctcttgcga ttgtcacccc
     1981 ctcaatacca gacgttaaag caggcaacaa gcctagattg tcaatttgga ggttctgagc
     2041 ttaatgtcat ctcaagcctt gctcagctag ggcatcaggt ctctcttatt tcagctattc
     2101 cagacaatga tctgggacaa atgacaaaaa cctttctctt ttcgcgtcaa attaatcagg
     2161 agcatattat cgaaaagggt cagcgtttag ggctttatta ttatcaaaag ggcttttctt
     2221 tgcgagcaag tcgggttacc tatgaccgct gtcattcagc cttttgggag tcaaagcgtg
     2281 ctgactatga tttggagcat gtttttgatg aggctgattg gtttcatgtg tctgggataa
     2341 cgcctgctct aacgagtgat ctttatgagc tgacctatta tttgatgaca aaggctaggg
     2401 cagagggatt gactatttcc tttgatttga attttagggc tagtctatgg tcctcctttc
     2461 aggaggctag agatctcttg tcgcctcttg ttcagctggc tgatgtttgt attggcattg
     2521 agccgctgac gcttaaggga agcggcgcgc ttgatttaaa ggatcaatta ggcttgaata
     2581 gaccctatga tgatgaagcc ttgttgaagg aggtgctggc taggttagct gatacctatg
     2641 gggtaaaatg ctttgccttt acccagagag agatggacta taccaatgaa tacctgttaa
     2701 aggcctacct gtatcaaaat ggcagccttt ataaaaccca aaaatctggt attcaggttc
     2761 tggaccgagt agggacgggc gatgctttta cggcagggct gattcatggc ttattaagtt
     2821 ataaagacga gcaggctact ttagatgttg caatggctag ctttaagttt aagcatacca
     2881 ttgagggtga tagtaatatc atgacacaag atgacattga tcatttactg gccaaggaat
     2941 cgcatgagat tcaacgataa tgtgataaag gagaaatcgt atgttatacc caatactgac
     3001 aaaaacaaga aagatttatg atttaggggg gctctggcaa tttaagctag gagaccataa
     3061 cccgcaggag ctcctagcct ctgatgagct gatggttgtg ccgacctcct ttaatgatgt
     3121 ggttgtggat aaggacaagc gcaattacat cggtgatttt tggtacgagc gctttgttga
     3181 tgtgccagat cttgctgctg atgaggagct ggtacttcgc tttggctctg tcacgcacaa
     3241 tgcaacagtc tatgttaatg ggcaagcttt agggcaacac aagggaggct tcactccatt
     3301 tgaggtgttg gtgcctgaga cccattatca ggataatcaa attaaggtat ctgtttgtgc
     3361 caataatatt ttagattata ccagccttcc agtgggcaat tatagtgaag aaactcaaga
     3421 ggatggcagt atcaaaaaaa ttgtcaagga gaattttgac ttcttcaact atgctggtat
     3481 tcaccgtcca gtgaagctta tggtgcggcc aaaatgccat atctcagata tcacgatcac
     3541 gagtgacttg tctgaggata tgacatcagc cttagtcgag gtatctgttg aaacctcagc
     3601 agctgttgat gaggttaagg tgacgatctt tgatgaagag cacaagctcg ttgcgcaggc
     3661 tattgatggc aaggcaagac ttgataaggt tcgtttatgg gaagttttag atgcttatct
     3721 atacactgcc cacgttgaga tcatcgtaga tggcaatgtt gtagatagtt atgatgagcc
     3781 atttggtatc agaagtattg cagttgaaaa aggacaattt ttactaaatg gcaagcctgt
     3841 ttatttcaag ggctttggta agcatgagga tacctttatc aacggtcgtg gattgaatga
     3901 agcagctaat ttaatggata tgaatctgct caaggagctt ggtgccaatt catttcgtac
     3961 ctcacactac ccttactctg aggagatgat gcgtctggca gatcgtatgg gaatcttggt
     4021 tattgatgag gttccggcag tagggctctt ccaaaacttt acagcctcct tggatctttc
     4081 gccaaaggac aatggcactt ggtctgtcat gaaaactaag gaagcgcatg agcaagcaat
     4141 tcgtgagctc gtcaagcgtg acaaaaatca cccttctgtt gtcatgtggg tcgtggccaa
     4201 tgagcctgcc agccatgaag agggagcaca cgaatacttt gagccgctga ttgctcttta
     4261 taaggcacta gatccgcagc agcgtccagt aacattggtt aatctgctat tagcaacacc
     4321 tgatcgagat aaggtgatgg atctggttga tgtgatctcc ttaaaccgtt attatgcttg
     4381 gtatgttgat catggagact tgatcaaagg agaggttggg ctgcgtcagg agctattaga
     4441 atggcagaag aagtttccta acaagcctat cctgatgaca gagtacggtg cagatacgct
     4501 tcctggtctt cattcgatgt gggatattcc atatacagag gaatttcagt gccgcttcta
     4561 tgagatgagt caccgcgttt ttgatgagat tcctaatcta gttggagagc aggtatggaa
     4621 ttttgctgat tttgaaacta atctgatgat cttccgtatt caaggcaatc ataaggggct
     4681 tttttctaga aatcgccagc ctaagcatgt tgttggtttg tttaaagagc gctggaatac
     4741 cattccccac tacaattata aaaagaaata gtgtacaata gtagctagca ataagtagga
     4801 agaagggatt gtatggctag gcctttagtc gaaaaaacag cagagcgctt gttaaagcta
     4861 attttagaac gtgggtatga ggttggagca aagctcccca atgaatatga gttagcacag
     4921 gacttagagg ttggaagaag cactattaga gaagctgtta gaagcttagc aactagaaat
     4981 gttttagagg ttagacaagg atcaggtact tatattagct cgaaaaaagg tgtttctgag
     5041 gatcctttag gcttttcctt agtcaaggac acagccaagc tgaccgctga tttgtttgaa
     5101 ttgcggctat tgcttgagcc taggattgcc gctttgacag cacagcatgc aacgccaaag
     5161 gaggttgaag ccttagagaa gcttgttgtt gatattgaag aggccgtagc tgctggtgat
     5221 cctaagcatt tgcagctgga tgtgaatttc cattccttga tggcaaaata cagtggcaat
     5281 attgctatgg atagcttgct accggtgatc aatcagtcga ttcatctgat caatgccaat
     5341 tacacaaatc gtcagatgaa agaagattct ctacaagccc acagagatat tctgaatgcg
     5401 attaaagcgg gagatccgat cgcggcacat gacgctatgc tcctgcacat catgacagtt
     5461 aagcgaacgg cttttctatc ataagcttaa gcttgcttgc cggaaacagt ctattgagtt
     5521 ttgagtgatt tgcttcttgg ctcgaataag agggcttggt tttagagata ctagaaccaa
     5581 gtcctttttt tgctttttcc ttgacaaatc atctgatgat ttatataata aaactaagac
     5641 aacggtttca tgaaaaggag gagcctatgc taaaccgatt aaaagagaat tatttttttg
     5701 ctattattcg tggaaaaaca gtagaagacg ctattgccat tgctaagcat gctattttag
     5761 gcggtattcg taatatcgag attacctatt ctactccaaa tgcttcagag gttattagaa
     5821 tattgtcagc tgagtttgag catgatgatg ctgtgattat tggagctggg acagtgatga
     5881 cgcctgatct ggcaagagaa gctattgcag caggtgctag ctttttagtt agtcctcatt
     5941 tttctagaga aatagcagag gttgccaatc aggcatcaaa tctttatttc ccaggctgtg
     6001 caacagctac tgaaattgtc acagcaatga atgcctcttg tccgattatt aaggtctttc
     6061 ctggaggtgt tgtaggacca ggctttatta aggatattca tggtcctatt cctgaggttg
     6121 atttgatgcc atcaggtggt gtgtcgattg acaatgtcaa ggagtggaaa aatgcaggtg
     6181 ctgttgctgt tgggattggt tcagccttag ctagccgagt tgaggctgag ggctatgata
     6241 gtgtaacccg tattgcagcg tcatttgtat cagcccttga ttaagggaat tggtcataag
     6301 aggaggacga gatggctttt aatgacgaca attttatgct aaaaaatgag gcagcaaagc
     6361 gcctctatca acaaatcaag gatcagccta tttttgatta ccattgtcac ttagatccaa
     6421 aggaaatttt tgaggacaag gtttatgaca atattgttga cctttggctt ggtggtgatc
     6481 attacaagtg gcgcttgatg cgcgctaatg gcatttcgga agaagaaatc acaggctcag
     6541 cctctaagct ggataaattc aaggcctttg cccgtacact tcagcgctcc tatggcaatc
     6601 ctgtttacca ctggtcagtg atggagttga aaaatgtctt tggtgtctgt gagctactga
     6661 ctgaggataa tgcagaggaa atctatcatc gtatcaatgc ttacttggtt gagcaccaga
     6721 ttagtcctag aaagttgatt gcagatagcc gagtgcggtt tattggtacg acagatcacc
     6781 cgcttgatga cctagcttgg cataagaggt tagctgctga tgataccttt gagacggttg
     6841 tcgcgccaac ctttagacca gatgaggctt ttattgagca tcagcgcttt gcagattttg
     6901 tggctcgtct tgctcaagct accggaagaa ctattacaga ttttaagagc tttatagcgg
     6961 ctatggaaga gcgtattgcc tattttgcag aaaatggttg taaggccagt gacatcagct
     7021 ttacagagat tgtctttgaa gcagcagagc cagagcaatt agaccgtctc atgacaaggg
     7081 ttttagaggg ctatcagccg cagccgttag aggtcaagca atggcagaca gcggtgtttg
     7141 cagagctttg caggctttat aagcactatg gctttgttac tcaggtgcat tttggtgctc
     7201 ttcgcaataa tcattcagct atattcaaca agctgggggc agatgtgggt gttgactcac
     7261 tgggagacca aacaggacta gcaatcaata tgaatcgcct gctggatcat ctggtgcaaa
     7321 gagacagcct gccaaagatg atttggtata acctaaatcc gagctataat atcgcggttg
     7381 ctaatacact agctaatttc caagccaatg aaaacggtat tgcgggctat ctgcaattcg
     7441 gtgcaggctg gtggtttgct gataccaagc ttggtatgat tagccagatg aatgccttgg
     7501 ctgagcaagg tttgttagct aattttgtcg gcatgctaac ggattcacgt tcatttttat
     7561 cctatcagcg tcatgattat ttcagacgta ttttgtcgac ctaccttggt gagtggattg
     7621 aagaaggtga ggtaccagag gattatcagg cacttggtaa aatggctcag gacattgcct
     7681 acaataatgc tatccagtat tttaactagg ctgccttggt cgttaactag aagaagcata
     7741 gaaatatgat gttgctctat gattaaggtc ctagtcttaa aagaggctag gacaatatcg
     7801 gcctgctagc tgctgtcggc gtcttgttga ttgactagat tacaaaggct agaccaagta
     7861 gcaggcccag gccctttagt tgcaagggta ttagccccaa aaacaataat aaataacaat
     7921 tgtgtgaatc gaaaggaaaa ggagtttacg agaactcgag gtatgatact atgaaaatgt
     7981 cgtttcgctg gtatggaaag catgatccag taagtttaga ggaaatcaag gccattcctg
     8041 gtatgcaggg aattgtaaca gctgtgtatg atgtaccagt tggtcaggct tggccactag
     8101 aaaatatcct tgaattgaag aggatagttg aggctgcagg ccttgagatt tcagtcatcg
     8161 aatcaattcc tgttcacgag gacatcaagc aaggaaagcc caatcgtgat gagctgattg
     8221 aaaattataa gacctctatc atcaatgttg gtaaggcagg tattcctgtg gtttgctata
     8281 attttatgcc agtgtttgat tggactcgct cagatcttaa ttacccattg cctgatggat
     8341 caacctcact tgctttttta aaggcagact tggcagatgt ggatcctgtg gcagatgatt
     8401 tgaacctacc gggttgggat ttttcttact caaaagaaga gatgaaggct attattgagc
     8461 attatcgtca tcatatttcc gaagaagacc tgtgggctaa tttagattat tttattaagg
     8521 ctattatgcc aacagcagag gcagctggcg ttaagatggc tatccaccct gatgatcctc
     8581 cttatggtat ttttggctta ccacgtatca taacaggtca aaaggctgta gagcgcttct
     8641 tagaccttta tgattcccct aataatggga ttaccatgtg tgtgggctcc tatgcttctg
     8701 atcctcaaaa tgatgtgatc gctatgacgg agtacgcgct taagcgccag cgtattaact
     8761 ttatgcatac gcgtaatgtc actgctggtg attggggctt ccaagaaacc gctcacttgt
     8821 cacaggctgg tgacattgat atgaatgcta ttatcaaatt attggttgat tatgactggc
     8881 aaggaccact tcgtccagat catggtcgtc gtatctgggg agatcaaacc aaaacccctg
     8941 gctatgggct gtatgaccgg gcacttggtg cgacctattt taatgggctt tatgaggcta
     9001 atatgcgtgc agctggaaag ataccagatt ttggcattac tgtaaaaaca gttggagata
     9061 aatagaaaaa ggggcatgag atgagtcgag ttattgaatt taaggacaag gttgttgtga
     9121 tcacaggagc tggcggtgtc ctttgtggca gtatggcaaa ggcatttgca aaagcagggg
     9181 ctaaggtggc actgttagac cttaaccaag aggcggcaca ggcctttgtt gatgatattg
     9241 aggcagaggg tggtattgca aaggcctatc aggcaaatgt attgtctaaa gaaaacctag
     9301 aggccgttcg tcaggcagtt ttagcagatt ttggtccagc agatatttta gtgaatggcg
     9361 ctggcggaaa cagccctaag gcaacaaccg ataatgagtt tcacgacaca agcctgccag
     9421 aggatacaaa aaccttcttt gaccttgatg aagcaggtat cagctttgtc tttaatttaa
     9481 actatttagg caccttgttg ccgacgcaag tctttgctca ggatatggtt ggtcgtaagg
     9541 gggcaaatat tattaacatt tcttcaatga atgcctttac gccattaaca aagatcccag
     9601 cctattctgg ggctaaggca gccatttcca actttaccca gtggttggct gttcattttt
     9661 ctaaggttgg cattcgttgt aatgccattg ctcctggatt tttggtaacc aatcaaaacc
     9721 gtagcctcct tttcacagag gacggacagc caacggctcg tgctgaaaaa atccttaaga
     9781 atacaccaat gggacgcttt ggtgaggcag aagaattaat tggaggcctc tttttcttgg
     9841 ctgatgagca gtctgcttcc tttgtgaacg gcgttgttct gccaattgat ggcggatttg
     9901 cagcttattc aggcgtctaa gctaaaaaat aaaccacttg agaactcaaa ctgcaatgcc
     9961 tcaagtggtt tttctatcgt gacagcttgc tttgtagcca agctgccatt aataaaggta
    10021 tgatgatttg tggcttctat tgttccttat cactctagcc ttttttagca atcaacaagt
    10081 aatgatagct tttaaaaatg aaacgctgct tgattaggat ttatgattga cagcgttttc
    10141 ttactgtgtt agaattaatt catcagatga tttggaggtt ggaatgacag ctaaaactga
    10201 acaatttgtc ttttgtgtgg actcagatgg ctgcgcaatg gacaccatga cttataagca
    10261 tcagctcttt tttggtccgc ttgcggcgga ttattttgcg gtagcagacc aagcgtcttt
    10321 cttaaaagag tgggatcgca ttaatcttta ttcgcgtaca cgcggtgtta accgctttgt
    10381 tgggcttgtt atggggctag aatacgcagg agttacaggg attgacgctt taaagcaatg
    10441 ggtacaacac actgcctcat tatccaatca gtctctggag gcggagcttc ttaagcgtcc
    10501 tagtgatgac ctgcaaaagg ccttggactg gtcaaatgag gtaaaccgtc agattgaggc
    10561 ctacaaagga gaggcattgg catttctagg agctttagct gctcttaagg ccttgcacca
    10621 gcttggccag gtttttgttg tcagctcagc taataaagag gccgttcaaa aggaatggca
    10681 ggatcaaggc ctgatgacac atgttgatgg cttgtattgt caggatcgtg gcaaaaaaga
    10741 ggctgtcata gcacagctca ttgatgaagg atatgtgaga gagcgcatga tgatgatagg
    10801 agattcacca ggtgatctag cagctgctga gcaaaaccag atcacttttt ttccaatcct
    10861 cgttggtaag gaggctagct cgtggcagga tctgtcacat gctgctgaag cttttacaac
    10921 tggtgacttg acagagcttg atgtcaagag ccttacagaa gccttctggc gtaatcttga
    10981 taggtaggca ggtagctgac cagtggagct gagcctgtta gggcttggta gcaggttgct
    11041 gtagcgccat tcattaaaac agaaaagcaa gcagagaagg ctttagttga aaggaagtac
    11101 aatgacacat ttagtagatt taagaaaaaa accatatagc ctagacgaag aagctatttg
    11161 ctgggtggag gataccattg cagcaatgac cttggaggag aagataggtc agctatttgt
    11221 taatatgggg gctagtcgat cagaggatta tttaactcag gtgcttgagg attatcatat
    11281 tgcagctgtt cgctacaata aaggcatggc ttcagaaatt tgggatcaaa attatatttt
    11341 acaaaccaaa tccaagattc caatgctcat tgctgccaat acagaggctg gtggtgatgg
    11401 tgctgtcaat gatggcacta aggttggtga tgaaatcaag gtagctgcga caaacgatcc
    11461 taaatacgct tatgaaatgg gacggattgc aggactggaa gcgtcagctg ttggctgtaa
    11521 tgcctccttt gcgccaattg ttgatttgac gcgtaattgg cgtaatccaa tcattgctaa
    11581 tcgcaactgg ggggtaaatg ttgatcaaat cattgagctt tccaaagagt atatgaaggg
    11641 gattatggaa tatggtatca tgccctttgc caagcacttc cctggtgatg gtattgatga
    11701 gcgtgaccat catttgtcct ttgcctcaaa cccaatgacc aaggaggagt ggctatctag
    11761 ctttggacgt atttatggcg agcttgcaga ggctggctta cctggtatta tggcaggaca
    11821 tattcacctg ccaaatgttg aaaaggccat gcaccctgag cgtgagctag atgatatgct
    11881 tccagcctca cttaataaaa ccctcttaga tgagctgctg cgtggtgagc ttggctataa
    11941 tggtgctatt gtgactgacg cttcgcatat ggttgcgatg acagcctcaa tgccacgtcg
    12001 cttattgtta ccaacagcga ttgaggcagg ctgcgatctc tttttattct ttaatgaccc
    12061 agatgaagac ctacaatgga tgaaagaggg ctatgaggca ggaattttaa gtgacgaacg
    12121 ccttcatgac gcccttcgtc gtacgcttgg cttgaaagca aagcttggac ttcatcgctt
    12181 tgaaggacac cgagaagata ttatgctgcc taaggacaag gcgatggtct tgattaacac
    12241 accagaggct caagcaattg cagatgaggt tgccgacaag gccattaccc ttgtgaaaaa
    12301 caagcaggca gggattttcc cggtaactcc agagcgctac aagcgtgtgc tgattgttaa
    12361 cgtggagggc tataagggtg gctttggtgc tatgattgca ggacagaaga aacgggcctc
    12421 agacattgtc aaggaattgc tagaggcgcg tgggcatgag gtaactgtct gggaatcaac
    12481 cgaagagcga atcatgcagc taccagagga agagcgtgca gcggctattg ctaatgttta
    12541 tgcacaaaag cagccgattt caaacattac agagcattat gatttaattc ttaatttggt
    12601 ggacgtcaat tctggaggta cagttcagcg tattatctgg ccagctgcta agggaacacc
    12661 ggatcagcca ttctacgtcc atgaggtccc aacaatcgtt gtttcagttc agcatgcctt
    12721 tgcccttgct gatatgccac aggttggtac ttatattaat gcctacgatg gcaaggacaa
    12781 cactatgaag gctttggttg caaaattagc tggtgaatct gaattcactg gagtgtctcc
    12841 tgttgatgcc ttttgtggct tgattgatac ccagctatgg catagcttct gaggttgcta
    12901 caggataagt agaggcttta cgtgttctgc ggtgattgct ctgaatgatt taaaaagatt
    12961 tcaggataaa acctgttaat cagccccttg tagctgcaga aatagcccca taatccctgt
    13021 ggtggggagt tttatccgat atggagatga tagagcctgt taatcctaaa gaaaagctag
    13081 agggtcattc tagcttttct ttttgtgcct aatgctcaac cttgcttcag atgatagaca
    13141 agctataagc ttgttgataa gtgaaacaat tgaacagata atgtttttta gagatgatat
    13201 attaagaata attttaaatt atgaaaaaat ataatatatt aatgat
//
LOCUS       DARYXS010000053        13010 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.054, whole genome shotgun sequence.
ACCESSION   DARYXS010000053 DARYXS010000000
VERSION     DARYXS010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13010
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.054"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            11..622
                     /locus_tag="TV193_001277"
     CDS             11..622
                     /locus_tag="TV193_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEL1513471.1"
                     /translation="MFKQDILKQRYFSFGIVAAAIALLAVVFAFSSENVNTDSYAKAS
                     DTKVVKKHHKTKKSTVAKAATKEQPAEQAEPSSADAAPAQESVASEVASPAVQEAAPQ
                     AQYAATPVAYSNGVILSNGNTAGAIGSEAAAQMAAATGVPQATWEAIIARESNGNPNA
                     ANPSGASGLFQTMPGWGSTATVQDQVNSALNAYRAQGLSAWGY"
     gene            complement(683..1318)
                     /locus_tag="TV193_001278"
     CDS             complement(683..1318)
                     /locus_tag="TV193_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEL1513472.1"
                     /translation="MKAILFDLDGTLVDSSIGILNAFEYTFQKMKIPCPDHSILSSYI
                     GPPLEATFSAFFRNQHDVEVAITHFRDFYRELGIYQARLYSGITELLDNLSQEGLDLY
                     VTTSKYEPMARQMLQDLTISHYFKAILGSISNRCHKLDIVKACLQDFAINKKEAIIVG
                     DTKFDMIGGKQAGITRLGVTWGFGCQEDLQAHGAQYIGHTPQEVIEIIQSL"
     gene            complement(1352..2224)
                     /gene="sdaAA"
                     /locus_tag="TV193_001279"
     CDS             complement(1352..2224)
                     /gene="sdaAA"
                     /locus_tag="TV193_001279"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEL1513473.1"
                     /translation="MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSRAEILSIMS
                     QHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGSSFALVAADMALANIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAA
                     TPTGRRYSKEIFGD"
     gene            complement(2236..2907)
                     /gene="sdaAB"
                     /locus_tag="TV193_001280"
     CDS             complement(2236..2907)
                     /gene="sdaAB"
                     /locus_tag="TV193_001280"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEL1513474.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGEIPD
                     EVTFHLYNSFAKTYQGHGTDKALVAGIMGMDTDNPNIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKAMSITGVSIGGGNIQVTELNGFSVSLSMNTPTLIIVHQDI
                     PGMIAKVTDILSASDINIAQMTVTRESAGEKAIMIIEVDSRDCQVAVKQIATIPNLHN
                     VNFFD"
     gene            3188..4312
                     /gene="mnmA"
                     /locus_tag="TV193_001281"
     CDS             3188..4312
                     /gene="mnmA"
                     /locus_tag="TV193_001281"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEL1513475.1"
                     /translation="MMTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDD
                     TDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRSGRTPNPDV
                     MCNKEIKFKAFLDYAMTLGADYVATGHYAQIKRDENGVVHMLRGLDKGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKSEVRAIAEQAGLATAKKKDSTGICFISEKNFKTFLSHYLPA
                     QKGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQQGGDNKPWFVVGKDLSQNILYVG
                     QGFYHESLMSTSLDASVIQFTREVPEEFTLECTAKFRYRQPDSKVTVHVKKDKAKVVF
                     AEPQRAITPGQAVVFYDGHECLGGGIIDMAYKDGEPCQYI"
     gene            4517..4981
                     /locus_tag="TV193_001282"
     CDS             4517..4981
                     /locus_tag="TV193_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1513476.1"
                     /translation="MVQDFRTRIADHSFGVRASALIIKDGYIYLAKSPKEDYYLLGGA
                     IHVGESTEEAVKREVLEEVGAEVSVAQLAFVVENQFCLEGVNFHQIEFHYIVSLLSDS
                     SPSVVEGDCTRVCEWVALDDLDKIRLNPSCLKRAIKHWDRQPQHIKHIEIKE"
     gene            4984..6882
                     /gene="mnmG"
                     /locus_tag="TV193_001283"
     CDS             4984..6882
                     /gene="mnmG"
                     /locus_tag="TV193_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEL1513477.1"
                     /translation="MVHEFTESYDVIVVGAGHAGVEASLAASRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQENLTLRQSMIDDILVENGRVVGVLTATGQKYAAQAVIITTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSIDYEVTE
                     IQPGDVTPNHFSFMSKDKDYLANQIPCWLTYTNQISHDIITKNLYRAPMFSGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGFDTEEVYVQGLSTSLPEDVQKELVHSIKGL
                     ENAEMMRTGYAIEYDIVLPHQLRATLETKMISGLFTAGQTNGTSGYEEAAGQGLVAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQIGLVDDERWSAFEIKKNQFDNELKRLDSIKLKPIKETNARVQKLGFKSLTD
                     AMTAKEFMRRPEVDYATVVSFIGPAAEGLDAKLIELLETEIKYEGYIKKALDQVAKMK
                     RMEEKRIPKTIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEG
                     NGKARRKT"
     gene            6970..8946
                     /locus_tag="TV193_001284"
     CDS             6970..8946
                     /locus_tag="TV193_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEL1513478.1"
                     /translation="MKRFRFETIHLIMMELILFGLLALCVRIMQSKMLITLAIFLVLL
                     FVAALLWYQKKVYELSDLDHIELLNEQTENNLKTLLDNMPVGVIQFDQETNAIEWYNP
                     YAELIFTDEAGFLQEQMIQQLLTDKRKSDISQTFEVSGNRYTSYIDVASGIFYFFDSS
                     VGSRQSADSSLLKPVIGIISVDNYDDITDDLSDADTSKINSFVANFIAEFMESKQVFY
                     RRVNMDRFYFFTDYKILKGLMDDKFSILEQFRKEAQEAQLPLTLSMGISFGEENHCQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPVYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISISQAMGLTTPRSLLVMVDHSKISLTLSKEFYEQFQDVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSRGSDSVEIQNISATDFDDYKQVNEIILRGERLSDSIIVATGLAGQYY
                     SNVIASKAADTILSMAHIEASFVIVETGADKIAISARSRSKINVQRMMEKLGGGGHFN
                     LAACQMKHISLSEAKQLLLETIDNTMKETREVES"
     gene            8943..9395
                     /gene="rplI"
                     /locus_tag="TV193_001285"
     CDS             8943..9395
                     /gene="rplI"
                     /locus_tag="TV193_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEL1513479.1"
                     /translation="MKVIFLVDVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEASSQAI
                     GQLRGQQKAEEKAQAEILAEAKAVKKILDDEKTRVQFKEKVGPDGRTFGSITAKKISE
                     ELQKQFKVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLNIAEA"
     gene            9416..10792
                     /gene="dnaB"
                     /locus_tag="TV193_001286"
     CDS             9416..10792
                     /gene="dnaB"
                     /locus_tag="TV193_001286"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEL1513480.1"
                     /translation="MEVLSLPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFIG
                     PEDFYKYSHKVIFRAMIRLSDRNDAIDATTVRTILDDQGDLQHIGGLSYIVELVNSVP
                     TSANAEYYAKIVAEKAMLRDIINRLTETVNLAYEGASDSEDIIASAEKALVDISEHSN
                     RSGFRKISDVLKINYENLEVRSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPA
                     VGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVNSHSLRTGQLTDQ
                     DWNNVTIAQGALAEAPIYIDDTPGIKITEIRARARKLSQEVEGGLGLIVIDYLQLITG
                     TRPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIE
                     QDADIVAFLYRDDYYRKESDSTEEALEDNTIEVILEKNRAGARGTVKLMFQKEYNKFS
                     TIAQFEER"
     gene            10809..11081
                     /locus_tag="TV193_001287"
     CDS             10809..11081
                     /locus_tag="TV193_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEL1513481.1"
                     /translation="MSDAFTDVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKVGRL
                     IEVYPSLFIIEYQGNPDASGEANNSYVESYTYSDILTEKTLIRYFD"
     gene            11605..12216
                     /gene="rpsD"
                     /locus_tag="TV193_001288"
     CDS             11605..12216
                     /gene="rpsD"
                     /locus_tag="TV193_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEL1513482.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGMGEKQFRNLFVQATKIKEGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSFRVEIGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(12423..12956)
                     /locus_tag="TV193_001289"
     CDS             complement(12423..12956)
                     /locus_tag="TV193_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1513483.1"
                     /translation="MDSRKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKEYQNKEHAFLEVFEFLKREQLLSALLSSNG
                     TREIQSFIINKVRLLITTDLQDKFSKDILSPTEKEYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTRFVLKMLSKT"
BASE COUNT         3886 a         2367 c         2871 g         3886 t
ORIGIN      
        1 tatttattta atgtttaaac aagacatttt gaaacaacgt tattttagtt ttggcattgt
       61 agcagctgct attgctttgc tcgcagtagt ttttgctttt tcaagtgaaa atgtaaacac
      121 tgattcctat gctaaagctt ctgatactaa ggttgtgaag aaacatcata aaacaaaaaa
      181 atcaacagta gcaaaggctg caaccaagga gcagccagct gagcaggcag agccttcctc
      241 tgctgatgca gcaccagctc aggaatcagt agcttctgag gtagctagtc ctgctgtgca
      301 agaggctgct cctcaagctc agtatgcagc tacaccagtg gcttatagca atggagtaat
      361 cctttctaac ggcaataccg caggggctat cggtagtgaa gcagcagctc aaatggcggc
      421 agctactggt gttccacaag ctacttggga agccattatc gctcgtgagt caaatggaaa
      481 ccctaacgca gctaatcctt caggtgcttc aggattattc caaaccatgc caggctgggg
      541 atcaactgca accgttcagg atcaggtaaa ttcagcctta aatgcctatc gtgcacaggg
      601 cttatcagct tggggctact aagaacagat aacagcgtta aaaacctatc atcttgtgtg
      661 atgataggtt tttagtatcg ttttacaatg actggataat ctcaatcacc tcttggggtg
      721 tgtgtccaat gtattgtgcg ccatgtgctt gtaaatcctc ttgacaacca aatccccaag
      781 taactccaag tcttgtaatg cctgcttgtt taccaccaat catgtcaaat ttggtatctc
      841 caacaattat agcttctttt ttattaatag caaaatcttg taagcatgcc ttgacgatat
      901 ccaacttgtg acaccgatta gaaatagagc ctaggatagc tttgaaataa tggctaatcg
      961 ttaaatcctg aagcatttgc cttgccatag gttcatattt actagttgtc acatagaggt
     1021 caagaccttc ttgcgagaga ttatctaata gctctgtgat tccagaataa agccttgctt
     1081 ggtaaatgcc taattccctg taaaaatctc taaagtgtgt tatagcaacc tcgacatcat
     1141 gctgattcct aaaaaatgct gaaaaggtcg cttctaaggg tggtccgatg taagacgata
     1201 atatgctatg atcaggacaa gggattttca ttttttgaaa ggtgtattca aaggcattta
     1261 gtattcctat actagaatcc accaaagtac catctaagtc aaataggatt gctttcatga
     1321 cgtctcctca gtctatcgtt acttgattat attagtctcc gaaaatttct ttactatacc
     1381 gtctacctgt tggggttgct gctaatcctc cctcagctgt ctccttaaag gctgttggca
     1441 ttgcggcacc aacctgatac atagcatcaa caacctcatc tacaggaatt tgtgactgaa
     1501 tattcgctaa tgccatatca gcagcaacaa gagcaaagct tgatcctaat gcattacgct
     1561 taacacaggg aacttcgact aagccagcaa caggatcaca aaccaatccc aatagatttt
     1621 tgatcacaaa ggctaccgct tggctagcct gataagcggt accacctgct gccttaacaa
     1681 gggctgcagc actcattgca gaggcagagc ccacctcggc ttgacagcct ccttctgctc
     1741 cggagataga ggcattattt ccaatgacta agccaaaggc acctgctgta aagagaaagt
     1801 ccagctgttc cttttctgat agcttgagct tatcaatagc aacagcaagg acagcaggta
     1861 gacagcctgc acttccagca gtcggggttg cacaaacaag tcccattttt gcatttagct
     1921 cattgacagc catagcattt ctcacagctg ttaaaatggt ttgatctgaa agcccctttc
     1981 cttttttgat gtaatgatcc atcttaagag catcaccgcc agtcaatccg ctaatagatt
     2041 tggttgctgt caatccgctg acaacagaat ccttcattac ctgtaaatgc tgtgacatga
     2101 tggataggat ttctgccctg cttcgaccag tcatttcaac ctctgtagca atcatcagct
     2161 ctgctacatt accatcaaac ctatcatcag cctgcttgac aagctcttca attgtgtaaa
     2221 acataatata cctttctagt caaagaaatt gacattatgc agattaggaa tagttgcaat
     2281 ctgcttgaca gcaacttgac aatcacgaga atcaacctca ataatcataa tggctttctc
     2341 acctgcactt tcacgagtca cagtcatttg agcgatatta atatcactag ctgacaatat
     2401 atctgtaacc ttagcaatca ttccggggat atcttgatgg acaataatca aggttggagt
     2461 attcatagac aaggaaacag aaaaaccatt tagctctgtg acctgaatgt ttcctcctcc
     2521 aattgacaca cctgtaatgc tcattgcttt atcagccttt ttgacactaa tctttacagt
     2581 attggggtgg ggagcattgc tatcctttaa aatatcccaa taaattttaa tgcccttttg
     2641 atgagcaatt tcaagagaat tcttgatgtt tggattatcc gtatccatgc ccataatacc
     2701 agctactagt gccttgtcgg taccatggcc ttgataggtc ttagcaaatg aattgtatag
     2761 atgaaaggtc acctcatcag gaatttctcc aaaaatggag tggacaacct ttccgattct
     2821 aacagcacca gcggtatgac tgctcgatgg tccaatcatc actggtccaa tgatgtcaaa
     2881 aactgattga aatttttgtg tgttcatata tgctccatgc tctttttatc ctttttatta
     2941 taacaaatcg ctaatcaaat gtcgtttgtt atgaaaaaag atattgttgg aaataagaga
     3001 caatactgtt ataatagtca tgcgtctagc ggcgcttcaa atcgaccttc aaatcgagct
     3061 ttgagaaaac acttggacaa agacaaaaaa tatagaaatg aaccatttgc tagagtcttg
     3121 tttaggcaag ttgattcgtt ctattctttt tctcatgtcc ttgtatctta tattgatggg
     3181 agaataaatg atgacagata actcgaaaac acgtgttgtt gttggcatga gtggcggtgt
     3241 tgattcatct gtaactgcct tgctgttaaa ggagcaggga tatgatgtga ttggcgtctt
     3301 tatgaagaat tgggacgata cagatgaatt tggtgtttgt acggcgactg aggattataa
     3361 agatgtggca gccgtagccg atcagattgg tattccttac tattctgtta attttgaaaa
     3421 agagtattgg gatagagtgt ttgagtattt cctagcagaa taccgttcag gacgcacccc
     3481 aaatcctgat gtcatgtgca ataaggagat aaagtttaaa gcctttcttg attatgcgat
     3541 gacattgggt gctgattatg tggcaacagg tcactatgcc caaatcaaac gtgatgagaa
     3601 tggtgtagtc catatgctgc gtggtcttga taagggtaag gatcaaacct attttttaag
     3661 ccaactatca caagagcaac tccaaaaaac catgtttccc ttggggcacc tgcaaaaatc
     3721 agaggtacgt gctattgctg aacaagcagg ccttgcaaca gcaaagaaaa aagactcaac
     3781 agggatttgt tttattagtg agaagaattt taagaccttt cttagccatt atttaccagc
     3841 tcaaaagggg cgtatgatga ctgttgatgg tcgtgatatg ggagagcatg caggcttgat
     3901 gtattatact attggccaac gtgggggact tggcattggt ggtcagcagg gtggagataa
     3961 caagccttgg tttgttgttg gaaaagacct ttcacaaaat atcctttatg ttggtcaagg
     4021 cttttaccac gagtccttaa tgtcaactag tcttgacgct tctgtcattc agtttacaag
     4081 agaagttcct gaagaattca ccttagaatg cacagcaaag ttccgctatc gtcagccaga
     4141 ttctaaggtg acggttcatg tcaagaaaga caaagctaag gttgtttttg ctgagcctca
     4201 gcgtgcgatt acacctggtc aagcagtcgt tttttatgat ggtcatgagt gtcttggtgg
     4261 tggtattatt gatatggcgt ataaagatgg cgagccttgt caatatattt agcttgacat
     4321 gttaattgac agatgtgtca ataaagttga cggttttgtc atctgataag tcttgacaag
     4381 ctggcagatt ttgatagaat aaggttaaca ataacgatga tggtcaaagc tcatgggaat
     4441 tgtaagtctt tttggcttac agctttctca ggttttgact atttttatag cttaaaaaca
     4501 gtgtcaagga gaaaagatgg ttcaggattt tagaacaagg atagcagacc atagctttgg
     4561 tgttagggct tcagcgttaa taattaagga tggctatatt tatcttgcca aatcacccaa
     4621 agaggactat tatcttttag gtggtgctat tcatgttgga gaaagcacag aagaagctgt
     4681 caagcgtgag gttctagagg aggtaggagc tgaggtttca gttgctcagt tagcctttgt
     4741 ggttgaaaat caattttgtc tagaaggagt gaactttcat cagattgagt ttcattatat
     4801 tgtgagtcta ttatctgatt ctagcccttc tgtagttgag ggtgattgta ctagggtttg
     4861 tgagtgggtt gctcttgatg atctagataa gataaggctc aatcctagtt gtttaaaaag
     4921 ggctataaag cattgggaca ggcagcctca gcatataaaa catattgaga taaaggagta
     4981 gatatggtac atgaatttac agaatcctac gatgtcatcg ttgtaggagc aggacatgca
     5041 ggtgttgaag ccagcttagc ggctagccgt atggggtgta aaaccttatt agcaacgata
     5101 aatcttgata tgctggcttt tatgccatgc aatccctcta ttggagggtc agctaagggt
     5161 attgttgttc gcgaaattga tgctcttggt ggagagatgg ggaaaaacat tgacaaaacc
     5221 tatatccaaa tgaaaatgct caatacaggt aagggaccgg cagttcgagc attacgagct
     5281 caagcagata aaagcttgta tgcacgtgag atgaagcata ctgttgaaaa gcaagaaaac
     5341 ctcactcttc gccagtctat gattgatgat attttagtag aaaatggtag ggttgttgga
     5401 gtgctgacag caacagggca aaaatatgca gctcaggcag tgatcataac aacaggtaca
     5461 gctcttcgtg gtgagattat ccttggagaa ttgaaatatt cgtctggccc gaataacagc
     5521 ttggcctcag tgacactagc tgataatttg aaaaagcttg gtcttgaaat tggccgcttt
     5581 aagacaggaa ccccaccacg tgtcaaggct tcttctattg attatgaggt gacagagatt
     5641 cagcctggtg atgtgactcc aaatcatttt tcctttatgt ctaaggacaa agattatttg
     5701 gctaatcaga ttccttgctg gctgacctac actaatcaga ttagtcatga tatcatcact
     5761 aaaaacctat atcgagcacc tatgttttca ggagtcgtca agggagtggg cccacgctat
     5821 tgtccatcaa ttgaggataa gattgtacga tttgctgata aagagcgtca tcagctcttt
     5881 ttagaaccag aaggctttga cactgaggag gtctatgttc aaggtctatc cacaagtctt
     5941 cctgaggacg tccaaaagga attggttcac tctattaagg ggcttgaaaa tgctgagatg
     6001 atgagaacag gctatgctat tgagtatgac attgtattac ctcatcagct tcgtgctacc
     6061 cttgaaacaa agatgatttc agggcttttt acagctgggc aaaccaatgg aacctcaggc
     6121 tatgaggaag ctgctggtca aggccttgtc gctggtatca atgctgcttt gaaggttcag
     6181 ggtaagcctg agctcatttt aaagcgcagc gacgcttata ttggtgtaat gattgatgat
     6241 ttggtaacca aaggaacctt ggagccttac cgtttgctga catcacgcgc agaatatcgt
     6301 cttatccttc gtcatgataa tgcggacatg cgattgactg aaattggtcg tcagattggc
     6361 ttggttgacg atgagcgttg gtctgccttt gaaatcaaga aaaatcaatt tgacaatgaa
     6421 ttaaagaggc tagatagtat caaattaaag ccaatcaaag aaaccaatgc tcgtgttcaa
     6481 aagcttggct ttaagtcctt gacggacgca atgacagcta aggaatttat gcgtcgacca
     6541 gaggttgact atgccactgt agtgtcattt ataggtcctg ctgctgaggg attagatgct
     6601 aagctgattg agctactaga aactgagatc aaatacgaag gctatatcaa aaaggccctt
     6661 gatcaggttg ctaaaatgaa gcgtatggag gaaaagcgga ttcctaagac cattgattgg
     6721 gacgctattg actcaattgc tactgaggca aggcaaaaat ttaagaaaat caatccagaa
     6781 accattggtc aggctagtcg catttcaggt gtaaatccgg cagatattag cattttaatg
     6841 gtttaccttg aaggtaatgg aaaggctcgc cgtaaaacat aatagtcatc aaattgtaat
     6901 ctcaaaacca ctgacagctc tgtatttcag ggctgtttta tggtataata cgggattaag
     6961 aggttaaaga tgaaaagatt tcgttttgaa accattcatt taattatgat ggagttgatt
     7021 ttattcggct tactagcctt atgtgttaga atcatgcaat caaaaatgct gattacacta
     7081 gctatttttt tagtgttgtt gtttgttgcg gccttgcttt ggtatcaaaa aaaggtttac
     7141 gaattgtctg atttagacca cattgagcta ttgaacgaac aaacagaaaa taatttaaaa
     7201 acattactgg ataacatgcc agttggtgtt attcagtttg atcaagaaac caatgctatt
     7261 gaatggtaca atccttacgc agagctgatt ttcactgatg aggccggttt tttacaggaa
     7321 cagatgatcc aacagcttct cactgataag cgtaaaagtg atatttctca aacctttgag
     7381 gtttctggca atcgatacac gtcttatatt gatgtggcat caggtatttt ttactttttt
     7441 gatagctctg ttggtagtag acaatcagca gattctagct tgctaaagcc agttattggt
     7501 attatttctg tggataatta tgacgacatt acagatgact tatctgatgc tgatacgtca
     7561 aagataaatt catttgtggc taatttcata gctgagttta tggagtctaa gcaggtattt
     7621 tatcgacgtg ttaatatgga tcgtttttac ttttttacag actataagat cttaaaaggg
     7681 ctgatggacg ataagttttc tattttagag cagttccgaa aggaagccca agaagcgcag
     7741 ctaccattga ccctaagtat gggcatttcc tttggagagg aaaatcattg tcaaattggt
     7801 caggttgctc ttgagaatct gaatattgct cttgtccgag gcggagatca gattgttatt
     7861 cgtgaaaatg cagaccatac aaatccggtc tattttggtg gcggctctgt ttctacggtt
     7921 aaacgctcta gaactaggac gcgtgccatg atgacagcta tttcagaccg tatcaaaatg
     7981 gttgataatg tgtttatcgt aggtcaccgt aaactggaca tggacgcctt aggctcggct
     8041 gttggcatgc aattttttgc tagtaacatt attgaaaaca gctttgctgt ctataatccg
     8101 gatgagatga gtccagacat tgaaagagct attgagcgct tacaggctga tggtaagaca
     8161 cgtcttatca gtatttctca agcaatgggg cttacgaccc ctagatcact gttagtaatg
     8221 gtggaccact ctaagatttc cttaaccttg tctaaggaat tttacgagca atttcaagat
     8281 gttattgtcg ttgatcatca ccgaagagat gatgattttc cagataatgc tatcttgacc
     8341 tttattgaaa gtggtgcaag cagtgccgca gagctagtga cagaattaat ccagtttcaa
     8401 aatgcgaaga agcgcttaaa caagattcaa gcaagtgttt tgatggctgg tattatgctg
     8461 gatactaaga atttttcaac acgtgtcacc agtagaacct ttgatgttgc cagttattta
     8521 cgaagcagag gtagtgatag cgtcgaaatt caaaatattt cagcaactga ttttgatgac
     8581 tataagcagg ttaatgagat cattctcaga ggtgagcgcc ttagcgactc cattatcgtt
     8641 gcaactgggc ttgctgggca atattatagt aatgtcattg ctagtaaggc agcagatacc
     8701 atactatcaa tggcccatat tgaggctagc tttgttattg tagagacagg agctgataag
     8761 attgctatat cagcaagaag tcgtagtaag atcaatgtcc aaagaatgat ggaaaagctt
     8821 ggcggcggag gacatttcaa cttagcagcg tgtcagatga agcatatcag tcttagcgag
     8881 gctaagcagc tgttactaga aacaattgat aacacaatga aagaaacaag agaggtagag
     8941 tcatgaaagt cattttttta gttgacgtta aaggaaaagg aaaaaaagga gaaatcaagg
     9001 aggttcccac tggttatgct cagaattttc tgattaagaa aaatttagca aaggaagcta
     9061 gcagtcaagc aattggccag ctaagagggc agcaaaaagc tgaggaaaaa gcccaggctg
     9121 aaatcctagc agaggctaag gctgttaaga aaatcttaga tgacgaaaaa actcgtgtcc
     9181 agtttaagga aaaggttgga ccagatgggc gtacctttgg ctcaattaca gctaagaaaa
     9241 tttccgagga attgcaaaag caatttaagg tcaaggttga caagcgtcat attgttttag
     9301 atcaccctat tcgtgctatt ggtcttatcg aagtgccagt taagctgcat aaagaagtga
     9361 cagctgaaat aaaactaaac attgctgagg catagcacat cagcctaaaa aagatttgga
     9421 ggtgctgagt ttgcctgaag ttgctgagtt acgagttcaa ccccaagatt tattggcaga
     9481 gcagtctgta ctaggctcta tctttatttc cccagacaag ttgattaccg ttagagaatt
     9541 tatcggtcca gaggattttt ataagtattc tcataaggtc attttcaggg caatgataag
     9601 gcttagtgat cgaaatgatg ctattgatgc aacaacggta aggacgattc ttgatgatca
     9661 aggggacctt caacatattg gtggcttgtc ttatattgtt gagctggtta atagtgtacc
     9721 taccagtgcc aatgcagaat actatgctaa aatagtagct gaaaaggcta tgctacgcga
     9781 tatcatcaat aggttgacag agactgtaaa cttagcctat gaaggagcat ctgactcgga
     9841 ggatattatt gcaagtgctg agaaggcctt ggttgatatc agtgagcata gcaatcgcag
     9901 tggctttcgt aagatctcag acgttttaaa gattaattat gaaaatcttg aggttcgttc
     9961 taagcagaca tcagacgtta caggtttacc aacgggcttt agggatcttg acaagattac
    10021 aacaggttta cacccagatc aactgattat tttagcagct cgtcctgcag tcggtaagac
    10081 agcctttgtc ttaaacattg ctcaaaatgt tggtacaaag caaaagagag cagttgccat
    10141 tttctcctta gaaatgggag ctgaaagcct tgttgatcgt atgctggccg ctgagggaat
    10201 ggtcaattca catagcttga ggactggtca gttgactgat caggactgga ataatgtgac
    10261 cattgcccaa ggagccttgg cagaagcacc tatctatatt gatgatacac ctggcattaa
    10321 gattactgag atcagagcaa gggcacgtaa attgtctcag gaggttgagg gaggcttagg
    10381 gctaattgtc attgattacc tccaactgat cactggtaca agacctgaaa atcgtcagca
    10441 agaggtttct gatatttcaa ggcagctaaa gattttagct aaggaattaa aagtgcctgt
    10501 tattgctttg agtcagcttt ctcgtggtgt tgagcagagg caggacaagc gtccagtttt
    10561 gtctgatatt cgtgagtctg gctctatcga gcaggatgcg gatattgttg catttttgta
    10621 ccgagatgat tattatcgta aagaaagcga cagcacagaa gaggctcttg aggataatac
    10681 aattgaggtg attcttgaga aaaatagggc aggtgcgcgt gggacagtta agctgatgtt
    10741 tcaaaaggaa tacaataaat tttcgacaat agctcaattt gaggaaagat aagaaagagg
    10801 gaaagagaat gagtgatgca tttacagatg ttgccaaaat gaaaaaaata aaggaagaca
    10861 ttaaggctca tgaaggtcag ttggttgagt taacacttga aaatggtcgt aagcgtgaaa
    10921 aaaataaggt tggcagattg atagaggttt acccttcttt atttatcatt gagtatcagg
    10981 ggaacccaga tgcttcaggg gaagcgaata attcttatgt tgagtcttat acctattcag
    11041 atattttgac ggaaaaaaca ctgattcgtt attttgattg aaaaatcaat gcccatttag
    11101 ggctttttct ttacactttg ttgacagctg tgtaaagata tgaatcaatt tgaagccttg
    11161 aagaacttat tagcaaatga atgaagcccg gactaataat agggactagc tttcttgaaa
    11221 agcagttact ctgagactct cggtattaga tatcaaaaca taatatgcta ttttcaaaga
    11281 atttcctatc ggtattaaaa agccttgttt actcgggaag tgttgtgtaa aagcttgttt
    11341 gccatatgat taacatcatc tttgagctta cagctaacca tttttgatga tatgatatta
    11401 aaaatgtaaa aaaaacttga atcaatacct ttttcatgtt acaattagtt ttgtgtgaaa
    11461 taacagcaga aaaatatgaa gctcgtcaac aggcggttaa ctaaattgag taacctttgc
    11521 tgtttaggcg aaaacctcct gcacgaatca ggatttttca aacagttatt tcctcgttat
    11581 attttttaga ggaggacatg atacatgtca cgttatactg gtccatcatg gaaacaatca
    11641 cgtcgtcttg gcttgtcatt gacaggcaca ggtaaggaat tggcacgtcg taactacgta
    11701 cctggtcagc atggccctaa caaccgtagc aagctttcag aatatggctt gcaacttgct
    11761 gagaagcaaa agcttcgctt ttcatatggt atgggggaaa aacaattccg taacctattc
    11821 gtacaagcta caaaaatcaa agaaggaact cttggtttca acttcatgct tcttttagag
    11881 cgtcgtcttg acaatgtggt ttaccgctta ggtcttgcaa ctactcgtcg tcaagcacgt
    11941 cagtttgtta accatggtca tattcttgtt gatggtaagc gtgttgatat cccatcattc
    12001 cgcgttgaga ttggccaagt catctctgtt cgtgaaaaat caatgaaggt tcctgcaatc
    12061 cttgaggcag ttgaagcaac tcttggacgt ccagcttttg tttcatttga cgctgaaaag
    12121 cttgaaggat cattaactcg cctcccagag cgcgacgaaa ttaacccaga aatcaatgaa
    12181 gcacttgtcg ttgaattcta caacaaaatg ctttaagata agactttata ttataagaag
    12241 cccacaacag tgggcttttt tggttgagcg gttagctgat ttatgtaccg accccaaagg
    12301 ttagaccaaa agtctaacga ttggaggtcg gtattgttag gcataaagat cattataaac
    12361 tcagtaagaa atagtttaca aagttgtttt ttggtactgg atttgacatc attagtgcag
    12421 gactatgttt tagatagcat ttttaagacg aaacgagtca tttcctgagg ggattctttt
    12481 tttcctttag caatccagct ttggcagaca ccgaaaaagg catgtgctag gtagatgctt
    12541 cgatattcct tttcggttgg ggacaagatg tccttactga acttgtcctg aagatcggta
    12601 gtgatcaaca gacgaacctt gttaatgata aagctttgga tttctcgggt accattggag
    12661 gatagcagag cagatagtag ttgctctcgc ttgagaaatt caaatacttc taaaaaagca
    12721 tgctccttgt tttggtattc tttttcaaaa atgtattcta atttgtgaaa aaaggtttgt
    12781 tgatagtaat caatcatctc atatttgtct ttatagtgag tataaaagct agaacgacta
    12841 atgcctgcca ttttagcaag ctgaacggtt gttacatcat cgaagctttc ggtttttagt
    12901 aagctcacca ttgcattaag aatggccttc ttggtttgct gcttgcggct atccatcatt
    12961 atctcctttt gaacacttgt agacattatg tctaaaaaat ttattttttc
//
LOCUS       DARYXS010000054        12930 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.055, whole genome shotgun sequence.
ACCESSION   DARYXS010000054 DARYXS010000000
VERSION     DARYXS010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12930
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.055"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(22..1071)
                     /gene="citC"
                     /locus_tag="TV193_001290"
     CDS             complement(22..1071)
                     /gene="citC"
                     /locus_tag="TV193_001290"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEL1513484.1"
                     /translation="MTQHLIQHIFPFDKQQKAKIDRLLQRQHIRRDPHLDYTCAIIDE
                     QGEPIATGSLYGNSLRCLAVDQAYQGEGLLNHIVSHLIEEAYSRGHHHLFIYTKIAAA
                     PLLLSLGFHVIAMVDDTLCFLENKKRGFEHYLSQLEKPQISPQKTAAIVLNANPFTLG
                     HLHLIEKACADNELVHLFMVSQDSSLIPYHIRKELIIKGTAHLANIIYHDSGPYMISQ
                     ATFPAYFQKDELAVIDSQAKLDIVIFRHIAEKLQIKSRYVGEEPTSMVTQHYNTVMLK
                     QLPCYSIDVQVIPRKTFAEGKIISASLARQAIKDDDYALLELLLPKTSLDFFRSEAAQ
                     PTITKIKAATDLKHY"
     gene            1338..2401
                     /locus_tag="TV193_001291"
                     /pseudo
     CDS             1338..2401
                     /locus_tag="TV193_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
     gene            complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TV193_001292"
     CDS             complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TV193_001292"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEL1513485.1"
                     /translation="MTKKVFDDISRLALKALLYEVSLSPKPGLVDQLDNGAHDDMSFL
                     TFVDSALALAPFFKIYLDIGFYHAKEDPGLIFERLRASGIEAEQAMFSATKGVNTHKG
                     VNFSLALLLGATGMYLADQPQLLDHVTAFTEEDSLAICQLVKPLTAHLLETDFGSLDL
                     KKELTYGEKLFLDYGIKGPRGEASEGYPTIAHKALPFLRKSLRSTDQETAQLQLLVYL
                     MSIVEDGNLIHRGGIKAWRQVKQDMLLLHNSSLSTADLKAALSAYNDKLIQKHLSPGG
                     TADLLVLSLYFAFLENQL"
     gene            complement(3364..4059)
                     /locus_tag="TV193_001293"
     CDS             complement(3364..4059)
                     /locus_tag="TV193_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1513486.1"
                     /translation="MNPIIEAVKNNLDLSRNIPLKIAFYNALKKTIILRQIPAGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIQDACEIFEIRKALET
                     LATSTAMYLMTEEDFQVMHDLLADCETFIEDDDLNRILDNFNSFNNLIYSYSQMVRLK
                     EIVTELQTYLVYFRKISISSLERRKRALSEHWMIYRGMKNRDHEQITLITHEHLNSSL
                     EFILQEMSRRQDD"
     gene            complement(4212..5615)
                     /locus_tag="TV193_001294"
     CDS             complement(4212..5615)
                     /locus_tag="TV193_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEL1513487.1"
                     /translation="MLLTVLAYAMIIIFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFTSDAKFVAFVGEDGLAKNLTAIGPMIMYGINNTAKTGIMLLFAILFFSIMLDAG
                     LFDPITEKMIRFAKGDPMKVLMATAIVAAAVSLNGDGTTTTLICCSAFLPIYKKLNMR
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLSVGPEILGYLAPGMVLSLLYVICWVAP
                     SMGRKERARLGVVDLTEEEMRKLTDITDPDTLSIRRPKNFAFNAILTIGLITWLVAGS
                     FYKAIAMAPLLLFAVGTCIALIVNYPVLKDQTKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALISAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYAIIIFII
                     FVVTIIAMGQMPLYIPQ"
     gene            5997..6341
                     /locus_tag="TV193_001295"
     CDS             5997..6341
                     /locus_tag="TV193_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513488.1"
                     /translation="MQFFQNMFRRSKKEAATSHQDRENKPEFPLDDWEPVPSYIAADK
                     KDYQTVSLIASAIAAGEQASSQFKVKRILQRNPEALTVSLIASSIAAGVYPESQFLVR
                     SIYSKKVNVSHK"
     gene            6359..6754
                     /locus_tag="TV193_001296"
     CDS             6359..6754
                     /locus_tag="TV193_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEL1513489.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPSQAPVVPPVQPAVAPAPVAE
                     KKAAEAPQAPAAPVSAGADAMPSPMPGIILKVLVNVGDVVHENQPLLILEAMKMENEI
                     VASTAGTVTGIHVTAGQVVNPGEGLITIS"
     gene            6804..7925
                     /locus_tag="TV193_001297"
     CDS             6804..7925
                     /locus_tag="TV193_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEL1513490.1"
                     /translation="METLIAGVTSITIPQIIMMLIGAVLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGTGVLTQVVNGVEQEGVFDALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQLTKILFPIVITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQAELF
                     LNVQTLLIIIFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            8107..8415
                     /gene="citD"
                     /locus_tag="TV193_001298"
     CDS             8107..8415
                     /gene="citD"
                     /locus_tag="TV193_001298"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEL1513491.1"
                     /translation="MEIKQIAVAGSLESSDMMITISPNDGQGIVLELDSSVEKQFGNH
                     IRALIKTTLARLGVESATIEAVDKGALDCTIQARTIAAVHRAAGVEHYNWKEIDSWNA
                     "
     gene            8403..9290
                     /gene="citE"
                     /locus_tag="TV193_001299"
     CDS             8403..9290
                     /gene="citE"
                     /locus_tag="TV193_001299"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEL1513492.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSNVETVVRVNSLDSCGALDIEAVVLAGVDVIRLPKTETAQDII
                     DVEAVIERVERDNGIAVGRTRMMAAIESAEGVLKAREIAKASNRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQAEVRHIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEISHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AQRVIALATAAGVLTEEDI"
     gene            9292..10824
                     /gene="citF"
                     /locus_tag="TV193_001300"
     CDS             9292..10824
                     /gene="citF"
                     /locus_tag="TV193_001300"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEL1513493.1"
                     /translation="MVKNKLGRDIPQEYADHYGVFEGELARITSYNESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLKDGMTISFHHHFREGDFVMNMVLDEIASMGIKDLAIAPSSI
                     ANVHEPLIEHIKNGVVTSITSSGLRDKVGAAISSGIMEKPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDEYGNVNGTIGKATCGSLGYAMIDAKYADQVVVLTDHLVDYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITQSPYFKNGFSF
                     QTGTGGASLAVTRFMREAMLQENIKASFALGGITNAMVELLEEGLVEKILDVQDFDYP
                     SAVSLGKNAQHYEIDANMYASPLSKGSVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEIGIAINP
                     NRPDLIEHFKDLKVPQFSIEELKEKAYSIVGTPDRIQYGDKVVALIEYRDGSLIDVVY
                     NV"
     gene            10817..11377
                     /gene="citX"
                     /locus_tag="TV193_001301"
     CDS             10817..11377
                     /gene="citX"
                     /locus_tag="TV193_001301"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEL1513494.1"
                     /translation="MSKELIFKGKAVTLADMLRAREDRSLRQGKLLTEFSNESLLSVT
                     MNIPGPIKTSPALLEVFDSVIKAILEKLSGNQISYQLRLLPKTGYEYYLVTALDSQAL
                     KLKMIELETDLPIGRLMDLDVLVLTNQLPTPISRTALGFPPRSCYLCSKEAKACSRNR
                     SHSVADMQTALVHLLQSFFDGGNQLS"
     gene            11408..12799
                     /locus_tag="TV193_001302"
     CDS             11408..12799
                     /locus_tag="TV193_001302"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEL1513495.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRTIRKVVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLETAVSATKEFGGHAQVAISYTTSPVHTIDYFVALA
                     KAYQAIGADSICIKDMAGVLTPETGYQLVKRIKESIALPLEVHTHATSGISEMTYLKV
                     VEAGADIIDTAISSFAGGTSQPATESMVIALEDLGIDTGVDMTRLTKIAEYFNTIRDH
                     YRAEGILNPKVKDTEPKTLLYQVPGGMLSNLLSQLKEQGLSDKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNVISGERYKVVPNEIKDYVRGLYGQPPAPLGEGIKEKII
                     GDEAVITCRPADLIEPQLPLLRQEIAGYACCEEDVLSYASFPQQAKDFLGRREDPFYD
                     IPVQYVTVDIAMD"
BASE COUNT         3787 a         2581 c         2858 g         3704 t
ORIGIN      
        1 tagagagggg gtagttgttg gttaataatg cttaaggtct gttgctgctt tgatcttagt
       61 tatcgtgggc tgagcagcct cgctcctaaa aaagtcaagt gaggtcttag gaaggagtag
      121 ctctaagaga gcataatcat cgtccttgat ggcctgtctg gcaagagagg cgctgatgat
      181 tttgccttct gcaaaggttt ttctagggat aacctgcaca tcaatgctat agcaaggcag
      241 ctgcttgagc atgacagtgt tgtaatgctg tgtgaccatg ctagtaggct cttcgccaac
      301 ataacgactc ttgatttgga gtttttctgc aatgtgacgg aaaatgacaa tatccaattt
      361 agcttgacta tcaataactg ctagctcatc tttttgaaaa taagcaggaa aggttgcctg
      421 actaatcatg taaggtccac tatcgtggta tatgatattt gctaggtgtg cagttccttt
      481 gatgattaat tcctttcgga tatggtaggg gatcaggcta ctgtcttgac tgaccataaa
      541 gagatgaacg agctcgttgt cagcgcaggc cttttcaatc agatgcagat gaccaagggt
      601 aaatggatta gcatttaaaa cgattgctgc ggtcttttga ggactgatct ggggcttttc
      661 tagctgtgac aggtagtgct caaagcccct ttttttattt tctaaaaaac aaagagtatc
      721 atcaaccatt gcaatgacat gaaagccaag acttagcaat agaggggcag ctgctatttt
      781 agtgtagata aacagatgat gatgcccacg tgagtaggcc tcctcaatca gatgtgagac
      841 aatgtgatta agtaagcctt ctccttggta ggcttgatca acagctaagc agcgcaggct
      901 attgccgtac aaagagccag tagcaatagg ctcgccttgc tcgtcaataa tagcacaggt
      961 ataatctaaa tgagggtctc ttctaatgtg ctgtctttgt aacaaacgat caatttttgc
     1021 tttttgctgc ttgtcaaagg gaaaaatatg ctgtatcaag tgctgcgtca tatgctcacc
     1081 tcttattacg aaattatcct cttgccttta ttatagcacg ctatagggct tattcttaag
     1141 catcttagct ggtttatgaa aagaatgcac aaaaaagaca tcaatgacct attgtctctg
     1201 atgtcattat gatatgatta ggacttttag ataaatgatt aaggtatgga ggatttaagc
     1261 ctgcaaaagg tggcaataat aattctgact tatgctataa tagagctatt gatattaagg
     1321 gggataaagg ggctggtatg ctttcgattc taatgacttt atttgttggg acgctgggag
     1381 ggcttgttgc taagcggctg agtattcctg ccccttttat gattggcagt atggtagctg
     1441 ttgccctagc ttctatcctg acaaagcagg tagaggctat taaccccatg aagatttttg
     1501 ctcagattat tagtggtgcc tatattggcc aaagcgtcag caaatctgac ctgcttaatc
     1561 tgcccaagct agccaagtct attattagtc tcatgtcctt gttcacgctg aatatgtttc
     1621 ttcttggtgg ggtatttgtt tactgctttg atcttgatcc tgtaacagcc ttgttgagct
     1681 gtttacctgg tggcattatg gacgtttctc ttatggcagt tgatatggga gcaaaggctg
     1741 atatagttgc gacattacag tcggctcgac tggtcggtat gctcttgttt cttcctgttt
     1801 gggtgacgtt ttgggtcaat cgctttgacc caaaagcaaa agctactaaa aaaaaaagat
     1861 agtcaaaagc gctagctccc aagatacaag accttctagg aaagagcagc tatggaataa
     1921 tgtccaggtt ttaagcattg ctaccattgg aggtttgatc ggtttagggc taaagatacc
     1981 tgtaggcgct ctgattgttt ctttgctttt ttcaacagca ctgaaggtgc ttcggcaaac
     2041 aagtcaaatg ccaagtacac ttcgttatat agcgcaggtt tttgctggct ctattattgg
     2101 aacaagcttt actcaggata gtttgcttca aatgggacgt ctgattgttc ctattctttt
     2161 acttttgagt agctatctga tcatcaatct cttttttggc tatatcatgt ataaaaaagg
     2221 tatcttggat ttgcaatcgg cactctttgc ctcatcgcct gctggtgcga cagacatttc
     2281 actattggct ggtgagcttg gcggagatat gcctaaaatc gctggtattc aaatcagtcg
     2341 aaccctctat actgttgtca tcatgccctt gttggttaaa tggctcatta gtatatggta
     2401 aacagaaaag cccctcagag cataaaccag agatacctag tcattaccaa ataacatatc
     2461 aaggatcttg ttcaggcttg gagctgctat aattgatttt ctaaaaaagc aaagtagagg
     2521 cttagcacta gcagatcagc agtccctcca ggactgagat gcttttggat cagcttgtcg
     2581 ttgtaggctg acaaggcagc ctttaagtca gcagtgctca aagagctgtt gtgcaatagc
     2641 agcatgtcct gtttgacttg ccgccaagct ttgatgcctc ctcggtgaat caggttgcca
     2701 tcttccacaa tagacatgag gtaaaccagc agttgcagtt gagcggtctc ctgatcagtg
     2761 ctgcgaaggc tcttgcgcaa aaaaggcagc gccttgtgag caattgtagg atagccctcg
     2821 ctggcttctc ctctagggcc ctttataccg taatctagaa agagcttctc accataggtg
     2881 agctcttttt ttaggtctaa gctaccaaaa tcagtctcaa ggagatgagc tgttagaggc
     2941 ttgacaagct gacaaatagc cagactatcc tcctcagtaa aggctgttac atggtccaag
     3001 agctgtggtt gatcggcaag atacattccc gttgccccaa gcagaagtgc taaggaaaaa
     3061 ttgactccct tatgggtatt gactccctta gttgcgctga acatggcttg ctcagcctca
     3121 atgcctgagg cacgcaagcg ctcaaagatc agaccaggat cttccttagc atggtaaaaa
     3181 ccaatgtcta aataaatctt aaaaaagggg gctaaggcca gagcgctatc aacaaaggtt
     3241 aagaagctca tgtcatcatg agccccgtta tcaagctgat ccacaagccc aggcttagga
     3301 gataaggaca cttcgtaaag taaagccttt agagcaagcc tgctaatatc atcaaatacc
     3361 ttcttagtca tcctgacgcc tgctcatttc ctgtaggata aattctagtg agctgttgag
     3421 gtgctcatgc gtaataaggg tgatttgctc gtggtcacga tttttcatgc cacgataaat
     3481 catccaatgc tcagataaag cgcgttttcg tctttctagg gaagagatcg aaatttttct
     3541 aaagtaaaca aggtaggtct gcaattcagt gacaatttct tttaatctga ccatctgact
     3601 atagctgtaa atcagattat taaagctgtt gaaattatct agaattctgt tgagatcgtc
     3661 atcttctata aaggtttcac aatcagccaa caaatcatgc atgacctgaa aatcttcctc
     3721 tgtcatcaaa tacatagcgg tgcttgttgc cagtgtttca agcgcttttc tgatttcaaa
     3781 gatttcacaa gcatcttgaa tactaacacc cttgacaata atgccttttt taggaatatg
     3841 ctctaccaaa tgctcctctg ataacaatcc tagagcgtac ctgattggtg ttctgctaat
     3901 atttagggca atggaaaatt ctttttcgtt gatacgactg ccagcaggaa tttgtcttaa
     3961 aataatagtt ttctttaggg cgttataaaa agctattttc aaagggatat tgcgggatag
     4021 gtcaagatta ttctttactg cttcgataat aggattcata taatctcctt aatgttcata
     4081 tcatgatatt attatactga aaatcattac taatgaaaat aataattagc ctcctaaaag
     4141 gcgaaagcca tgctcgtgaa agaacatggc tttcattagc ccacactaca gtcctaataa
     4201 tagctcgtga cctattgtgg aatgtaaagc ggcatttgtc ccattgcaat aatggttaca
     4261 acaaagataa taaagataat aatcgcgtat ttagcagctt ctttttgcca ttctcccata
     4321 tcaagcccag taagacgaag aagcaggtaa ataaaggcca ccaatggact gagcaaatgg
     4381 aaggcttgtc ccatcagaga agcaagagcc atcgccatgt tgctaaagcc atattcagct
     4441 ccagcctccg ctaagactgg caaaatacca tagtagaagc catcatttga gataaagaaa
     4501 gtaccaggag ctgaaatcag ggcaataaca agtccccaga agccagccaa ttgctttgga
     4561 ataatcgttg caaagctttg agcaagagca ctagccatac cagagccttg gaaaagtccc
     4621 atgaagatac cagcagcaaa aaccagaata acaacctgaa cagcatcacc ggcattatca
     4681 ccaatacgct ttgtttggtc ctttaggaca ggatagttaa caataagggc aatacaggtt
     4741 cccactgcaa ataaaagaag tggtgccata gcaatagcct tatagaaaga gccagcaacc
     4801 agccaagtga ttaagccgat ggttaagata gcattaaagg caaagttttt aggacgacgg
     4861 atagaaagcg tatctggatc tgtaatgtct gttagcttac gcatttcctc ttcggtcaaa
     4921 tcaacaacac caagtcttgc acgctccttg cgtcccatgc ttggcgcaac ccaacaaatg
     4981 acataaagaa gagacaaaac cataccaggt gcaaggtatc caaggatttc aggtcccaca
     5041 ctaagcacag acatggcacg cgcagttgga ccaccccaag gaagcaggtt catgatagtg
     5101 ttttgcagga taatcaagac accaagattc atgatgcgca tgtttaattt cttatagatt
     5161 ggtaaaaaag cagagcagca aatcaaggtt gttgttgtac catcaccatt aagtgaaaca
     5221 gctgctgcaa caattgcagt tgccatcaag accttcatcg ggtctccctt agcaaagcga
     5281 atcatttttt cagtaatcgg gtcaaacaag ccagcatcta gcataatgga aaagaacagg
     5341 atcgcaaaaa gcagcataat acctgtctta gcagtgttat taataccgta catgatcata
     5401 ggaccaatag ctgtcagatt tttagcaagc ccatcctcac caacaaaggc aacaaatttg
     5461 gcgtctgatg taaaatcagc agagcctgtt aatataacag caattgtcat tatcaacgga
     5521 atcatgacca gagctgtaaa aggggtcatt tttttcttca tgacgacata catgaagata
     5581 ataatcatag cataagctag aactgttaat aacatattgt tatctccttt ttgattttat
     5641 gacttcagta taaatgaaag cgttcgcaaa agaaatacct ccatgtacgg aaaaacacaa
     5701 aaaaaacatt ttgaaagcag atcctgaaaa aataaatggt tacattaatg tttttcaaca
     5761 gcagttagtt gctcttatct tcagtaatcg cagtgtgttt cagcattttt taaaatcagt
     5821 catatttatt ttagttaact gtttttataa aaatggttaa ctaaaataag aaaatccttg
     5881 aaaatgtgaa agcgctctta gaaagaacac aaaaaagcca ttccaaaagg atgaggtggt
     5941 atataataag catagaagct tcccatttgt gggcaaacta agaaaggagg tagcttatgc
     6001 agttttttca aaacatgttt agacgctcta aaaaagaggc agccacaagc catcaagaca
     6061 gagaaaataa gcctgaattt ccgttagatg actgggagcc agtgcctagc tacattgctg
     6121 cagataaaaa ggattatcag acagttagtc tgattgccag tgccattgca gctggcgagc
     6181 aagctagcag tcagtttaag gtaaaacgaa tcctacagcg caatcctgag gccttaaccg
     6241 tatccttaat agcatcaagc attgcagctg gtgtttatcc agagagtcaa tttctggtta
     6301 ggtccattta tagtaagaaa gtaaacgtta gccacaaata gtaaaaggag aaaagattat
     6361 gttgcgtaag tttaaaatta ccattgacgg aaaagagtac ctagttgaaa tggaagaaat
     6421 cggtgctccc tcccaagccc cagtagtacc tcctgttcaa ccagcagtag ctccagcccc
     6481 tgtagccgaa aaaaaggcag cagaagctcc gcaagctcca gcagcacctg tatcagcagg
     6541 ggcagatgca atgccctcac ctatgcctgg tattatctta aaggttttag ttaatgttgg
     6601 tgatgtcgta catgaaaatc agcctctatt gattttagag gctatgaaaa tggaaaatga
     6661 gattgtcgcc tcaacagctg gtacagtcac agggattcat gttactgcag gtcaggtggt
     6721 caaccctggt gaaggcttaa tcaccattag ctaatcctaa gtcgtgtctt gatttaaaat
     6781 gttgtagaaa aggaagtaca tttgtggaaa cattaattgc aggagtaacc tccatcacta
     6841 ttcctcaaat cattatgatg cttatcggtg ctgtcttaat gtatctagga ataaaaaaag
     6901 aatacgaacc aaccttacta gttcccatgg gactgggtac tattttagtc aactttcccg
     6961 gcacaggagt cttaacacag gttgttaatg gtgttgagca agaaggggtc tttgatgcct
     7021 tattcaattt tggaatcggt acagagctgt ttccattact tatttttatc ggtattggtg
     7081 ccatgattga ctttggtcct ttacttcaaa atcctttcat gctattattc ggtgcggcag
     7141 ctcaatttgg gattttcttt gttgtcgttg tagccgtatt agctggcttt gatattaagg
     7201 aagcagcttc aattggtatc attggtgctg ctgacggtcc aacatcaatt tttgtagcaa
     7261 accaattggc aaaggatttg ctagggccta tcacagtggc agcttattct tacatggctt
     7321 tggttccgat cattcagccc tttgcgatca agctagttac taccaaaaaa gagcgtcgta
     7381 ttcgtatgac ctataaggct gagaatgtgt cacaattaac gaagatcctc tttcctattg
     7441 tgatcacact tgtagccggc tttattgctc caatttcgtt accattggtt ggttttttga
     7501 tgtttgggaa cctgcttcgt gaatgtggtg tcttggaccg attgtcacag accgctcaaa
     7561 acgaattggt caatatcatc agtattttac taggactaac catctctatc aaaatgcagg
     7621 ccgagctttt cttgaatgtg caaaccctgc ttattatcat ttttggtctg ttggccttta
     7681 tcatggattc gattggtggt gtgatgtttg ccaaattctt gaatttattc cgtaaggaaa
     7741 aaatcaaccc aatgatcgga gctgctggaa tttcagcctt tccaatgtca agtcgtgtga
     7801 ttcaaaaaat ggccactgat gaggatccgc agaatttcat cttgatgtat gctgtgggtg
     7861 ctaatgtatc tggtcaaatc gcctcagtta ttgcaggtgg cttgctgctt gcttacttta
     7921 gctaagaaag gacgtgctta tgacaatcaa tatagaccat ttgatccaat cctttgagct
     7981 aatggcactt ggaatggcag gagtatttgt tgtattagga attctctata ttgtagcaga
     8041 ggctctgatt aagctatttc cagtagaaaa ataatagaat atgatctaaa caaggaggtc
     8101 aatcaaatgg agatcaaaca aattgctgtt gctggttcgc ttgaatctag cgacatgatg
     8161 ataacaatat cacctaatga tggtcaggga atcgttttgg aattggattc aagcgttgaa
     8221 aaacaatttg gcaatcatat cagagcatta atcaagacaa cacttgccag gctgggcgtt
     8281 gagtcagcaa cgatcgaagc tgttgataag ggagccttgg attgtaccat tcaggcaaga
     8341 acaattgcag cagtccatcg tgctgctgga gttgagcatt acaactggaa ggagatcgac
     8401 tcatggaacg cttaagaaga acgatgatgt ttgttccggg cgctaatgcg gctatgctaa
     8461 gagatgcacc cttgtttgga gcggactcta tcatgtttga tttagaggat tcagtttcct
     8521 taaaagaaaa agacacctct cgcgcccttg ttcattttgc cctaaaaacc tttgattatt
     8581 caaatgttga gacagttgtg cgcgttaata gcctagactc ttgtggtgct ctggatattg
     8641 aggcagttgt gttagcaggt gttgatgtta ttcgcctgcc aaagacagaa actgcccagg
     8701 atattattga tgttgaggca gtcattgagc gtgttgagcg tgacaatggg attgctgttg
     8761 gtcgtacacg catgatggca gctatcgagt ctgcagaagg ggtcttaaaa gctcgtgaga
     8821 ttgcaaaggc ctcaaatcgt ctcattggta ttgccctcgg cgcagaggat tatgtgacta
     8881 atatgaaaac acgtcgctac ccagatggac aagaattatt ctttgcccgc agcatgattc
     8941 ttcacgcagc acgtgctgct gggattgcag caattgatac cgtttattca gatgtcaaca
     9001 atacagaagg cttccaagct gaggtgcgtc atatcaagca attaggcttt gatggtaaat
     9061 ctgtcatcaa ccctcgtcag attccattgg taaatgagat ttatacacca accgaaaaag
     9121 agattagtca cgccaagcaa gtgatctggg ccattcgtga ggctgaaagt aagggatcag
     9181 gtgtcatttc attaaatgga aaaatggtag ataagccaat cgtagagcgt gcacagcgtg
     9241 ttatcgcttt ggcaacagct gctggggtat taacagagga ggacatttag catggttaaa
     9301 aataaacttg gtcgtgatat tcctcaggag tatgctgatc actatggagt atttgaagga
     9361 gagctagcac gtatcactag ctacaatgaa tcaagccgcc gcattaagcc tgtaaagcca
     9421 ggtgacagta aattgcttgg ctctattcgt gaagctattg aaaagacagg cctaaaagat
     9481 ggcatgacca tttcatttca ccatcatttt cgtgaggggg acttcgtcat gaatatggtt
     9541 cttgatgaga tagccagcat gggaatcaaa gatttagcta ttgctccaag ctctattgcc
     9601 aatgtgcatg agccattaat tgagcacatt aaaaacggag tggttacaag cattacctca
     9661 tcaggtttac gtgataaggt tggggcagct atttcatcag ggattatgga aaagcctgtt
     9721 gtgattcgtt ctcatggagg acgtgctcgt gcgattgcta gtggtgatat tcatattgac
     9781 gttgcctttt taggagcacc aagctcagat gaatatggta atgtcaacgg tacgattggt
     9841 aaggctacct gcggctcact tggctatgct atgatcgatg ccaagtacgc agatcaggtg
     9901 gtggtgctga cagatcacct agttgattat cctaacaccc caattagcat tccgcaaact
     9961 gatgttgatt atgtcgtgac agttgatgct attggtgatc cacaaggaat cgctaaggga
    10021 gcaacgcggt tcaccaaaaa tcctaaggag ctcctaattg ccgaatatgc cgctaaggtt
    10081 atcacacagt cgccttactt taaaaatggc ttttccttcc aaacaggtac aggaggagct
    10141 tccttagcag tgactaggtt catgcgtgag gccatgcttc aagaaaatat caaggcaagc
    10201 tttgcccttg gaggcattac aaacgctatg gtagaattgc tcgaagaagg attagttgag
    10261 aaaatcctag atgtacagga ttttgattac ccttcagcag tttcgcttgg taaaaatgct
    10321 cagcattacg aaattgatgc taacatgtat gcctcaccac taagcaaggg atcggttatc
    10381 aatcaattag acacctgtat tttatcagcg cttgaggttg acactaattt caatgttaat
    10441 gtcatgacag gttctgacgg tgttattcgt ggggcttccg gagggcattg tgacacagcc
    10501 tttgctgcca aaatgagtct ggtgatttca ccccttatcc gcggacgcat tccaaccttt
    10561 gtagatgagg taaatacagt aattacacct ggaacaagcg ttgatgtggt tgtcacagaa
    10621 ataggtattg ctatcaatcc aaaccgtcca gatttgatag agcatttcaa ggacttgaag
    10681 gttcctcaat ttagtatcga agaattaaaa gaaaaggctt actcgattgt tggaacacct
    10741 gatcgtatcc aatacggtga taaggttgta gctcttattg agtatcgtga tggcagcctg
    10801 attgacgttg tctacaatgt ctaaggaatt gattttcaag gggaaagctg ttaccctagc
    10861 tgatatgcta agggcacgcg aggacagaag ccttcgtcaa ggaaagcttt taacagaatt
    10921 ctcaaacgaa agcctgcttt ctgtgaccat gaatattcca ggccccatta aaacgtcacc
    10981 tgctttactt gaggtatttg atagtgttat caaggcaatc ctagaaaagc tgtctggcaa
    11041 tcagatcagc tatcagcttc gtttgctgcc aaaaacgggt tatgaatatt accttgtgac
    11101 agccttagat agtcaggcat taaagctcaa aatgattgag cttgagactg atttaccgat
    11161 tggcaggcta atggatttgg acgttttagt gctgacaaat cagctgccaa cccctatcag
    11221 tcgaacagcc ttaggctttc ctcctcgcag ctgctatctt tgctcaaaag aggctaaggc
    11281 ttgtagtaga aatcgcagtc actcggtagc agacatgcag acagcccttg tacacttact
    11341 ccaatcattt tttgacggag gcaatcagct cagttagact caacggtatt cttataagga
    11401 gaatgatatg acaaaaatcc gtataacaga aacagttttg cgtgatggtc agcaaagtca
    11461 aattgctacc cgcatgacta caaaggaaat gattccgatt ttagaaacac tagataatgc
    11521 tggctatcat gccctagaaa tgtggggagg agctaccttt gattcttgcc tacgtttctt
    11581 aaatgaagac ccttgggagc gtctaagaac cattcgtaaa gtagtcaaga aaactaaatt
    11641 acaaatgctc ctgcgtgggc aaaatctttt gggctatcgt aattatgctg acgatgtcgt
    11701 ccgcagcttt atccaaaaat caattgaaaa cggtattgat attgtgcgca tttttgatgc
    11761 cctaaatgat ccacgtaatc tagagacagc tgtttcagca acaaaagaat tcggtggcca
    11821 tgcacaggtt gctatttctt acacaacaag tccagttcat actatcgatt attttgtagc
    11881 cttagcaaaa gcctatcagg ctattggtgc agattcgatt tgtatcaagg atatggctgg
    11941 tgtgttaacc ccggagaccg gttatcaatt agtgaagcgt atcaaggaaa gcattgctct
    12001 accacttgag gttcacacgc atgctaccag tggtatttct gaaatgacct atctcaaggt
    12061 cgtagaggct ggtgcagata ttattgatac tgccatatcc tcatttgccg gcgggacaag
    12121 ccagccagca acagaatcga tggttattgc tttagaggac ttggggattg ataccggagt
    12181 agacatgaca aggctgacaa aaattgccga gtattttaat actatccgag atcactacag
    12241 ggcagagggc attttaaatc ccaaggttaa agacactgag cctaagacct tgctttatca
    12301 ggttcctggc ggcatgctgt ccaatttgct aagtcagctt aaggaacagg gactctctga
    12361 caaatatgaa gaggttctgg ctgaggttcc aaaggttaga gctgatttag gctacccccc
    12421 actggtgact ccgctatcgc aaatggttgg cacacaggcc ttaatgaatg ttatttcagg
    12481 tgaacgctac aaggttgtcc caaacgaaat caaagactat gtcagaggac tttatggcca
    12541 acctcctgcg ccactaggtg aaggtattaa agagaaaatc attggtgatg aagctgttat
    12601 cacttgtcgt ccagcagatt tgattgagcc acaattgccc ttgcttcgtc aagaaattgc
    12661 aggctatgcc tgctgtgagg aggatgtgct gagctatgcc tctttccctc agcaggcaaa
    12721 ggatttccta ggacgcagag aggatccctt ttatgatatc ccagttcagt acgtcaccgt
    12781 tgatatagca atggattaat caaaagaata aaaagcaaga taactaataa aatcaatctc
    12841 ctaattatta gtcaaagcta cctaccaata aactccttaa tcagaaccac ccgtctaatg
    12901 aggtgccccc aaaaggttag tccaaaactt
//
LOCUS       DARYXS010000055        12635 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.056, whole genome shotgun sequence.
ACCESSION   DARYXS010000055 DARYXS010000000
VERSION     DARYXS010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12635
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.056"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            35..610
                     /locus_tag="TV193_001303"
     CDS             35..610
                     /locus_tag="TV193_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL1513496.1"
                     /translation="MKKVINTILLAACFLFFLGNFTTNVLAEGINDKIENGTESDISF
                     QNGELLKNYLILEGERVYFDYDRATQDKVSDDVLEMGMLVEAISKDYSEKTFTPDKYF
                     KASWPIHGNYCGPGHNGNNFTLPVVDVLDQGCQNHDSCYKWGAGIGANCECNRQLVNY
                     IKVYRRWMPANVLGVADAIRVYFETVGSIGC"
     gene            959..1141
                     /locus_tag="TV193_001304"
     CDS             959..1141
                     /locus_tag="TV193_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1513497.1"
                     /translation="MLTYDEFKQAVDNGYITGDTVTIVRKNGQILDYVLPHEEVRNGE
                     VVTDEKVEEVMRELDK"
     gene            1339..1728
                     /locus_tag="TV193_001305"
     CDS             1339..1728
                     /locus_tag="TV193_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEL1513498.1"
                     /translation="MFYLAVHDQFDKKSRLAEIAKSRAGVISIDHIDCYHGTQSYLSL
                     FGKNKAGNTIIVTIEEQSEQLLLSRPSNGISAKEAQEIAYHAGARTIEAVTFGIENHK
                     RIWEVAAQNGYYLIDFKTAKVIKKEVL"
     gene            1725..2936
                     /locus_tag="TV193_001306"
     CDS             1725..2936
                     /locus_tag="TV193_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1513499.1"
                     /translation="MTKLSRRVLAMEESVTLAAGARAKALKAQGRDILSLTLGEPDFI
                     TPQHIQEKAIEAITTGKASFYTVASGLPELKDAIADYMARSYGYIPTRQEIVVGTGAK
                     YVLYAFFMAVLNPGDQVLIPTPYWVSYADQIKMVDGVPVFVQGLEENQFKVTVEQLEA
                     ARTDQTKVVLINSPSNPTGMIYSRQELEAIGNWAVQHDILILADDIYGALVYNGNQFT
                     PISALSEAIRRQTITVNGVAKSYAMTGWRLGFAVGDTDIIAAMGKIIGQTTSNVTTAS
                     QYAAIEAFGGDQTSVEEMRQAFEERLNTIYPLLNQVPGFEAIKPQGAFYFFPNVKKAM
                     EMKGFTDVTAFTDAILEEVGLAVVSGAGFGAPENIRLSYATDLATLKEAIRRLNQFMT
                     TDSSHDNKENE"
     gene            2949..4295
                     /gene="asnS"
                     /locus_tag="TV193_001307"
     CDS             2949..4295
                     /gene="asnS"
                     /locus_tag="TV193_001307"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEL1513500.1"
                     /translation="MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSA
                     FFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITD
                     LEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
                     IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYPFLSHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTE
                     LLKRYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSPHETWISNYFGVPT
                     FVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAE
                     GLNPEDYDFYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP"
     gene            4596..5690
                     /locus_tag="TV193_001308"
     CDS             4596..5690
                     /locus_tag="TV193_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1513501.1"
                     /translation="MMNRKKHTKLIRHYSICSAVAVLAAVSLGTGQDVQASEPNPYPD
                     VRRFLDEKYDGDVDKLSKQLQGYFGSLREYIEFELKNGKQGPAGPQGPKGDKGDPGEP
                     GPQGPVGPAGPKGDRGLDGRRGPAGQQGEVGPVGPQGPQGEQGPKGDRGEQGPKGERG
                     EQGPKGERGEQGPKGDRGEQGPKGERGEQGPKGERGEQGPKGDRGEQGPKGERGEQGP
                     KGDRGEQGPKGERGEQGPKGDRGEQGPKGDRGEQGPKGDRGEQGPKGDRGEQGPKGER
                     GEQGPKGDRGEQGPKKEPEKDTKPSVPKAPDNMAAPKAPEKKNPKAPAPKSAPKASLP
                     STGDTSQSFVAAALGFIASAGLLVFKRKKN"
     gene            6216..7106
                     /gene="rapZ"
                     /locus_tag="TV193_001309"
     CDS             6216..7106
                     /gene="rapZ"
                     /locus_tag="TV193_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEL1513502.1"
                     /translation="MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPK
                     FLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNANLKLRILFLDATDSELVS
                     RYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFS
                     SESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVM
                     THQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTAD
                     WPLHESHRDINRRKETVNRS"
     gene            7103..8080
                     /locus_tag="TV193_001310"
     CDS             7103..8080
                     /locus_tag="TV193_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEL1513503.1"
                     /translation="MRNPKITVIGGGTGIPVILKSLRKEAVDITAVVTVADDGGSSGK
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNEADGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIFPSSEQPLTLHAVFKDGHEVSGESSIASYQGMIDHVY
                     VTNTYNDDLPKASRKVVEAILQSDMIVLGPGSLFTSILPNLVIPEIKEALRVTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVEQVPKSYMNSNQFDEYLV
                     QVEHDFAGLCKTAKRIISSNFLRLENGGAFHDGHLVVEELMNLVRITKL"
     gene            8077..8988
                     /gene="whiA"
                     /locus_tag="TV193_001311"
     CDS             8077..8988
                     /gene="whiA"
                     /locus_tag="TV193_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEL1513504.1"
                     /translation="MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSIT
                     TENAKIARYIYALIEDTYHIIPEIRYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADS
                     FFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDIN
                     RANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQI
                     ADSLDFAITKSGVNHRLRKINKLAEDL"
     gene            9348..10745
                     /locus_tag="TV193_001312"
     CDS             9348..10745
                     /locus_tag="TV193_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEL1513505.1"
                     /translation="MSCTTILVGKKATYDGSTIVARTEDSQNGEFTPKKMTVVRPKDQ
                     PRHYQSVLSSFSMELPDQPMAYTSVPDALGKDGIWGEAGVNTLNVAMSATETITSNAR
                     VLGADPLVSSGIGEEDMLTLVLPYIRSAREGVLRLGAILEAYGTYEANGVAFSDEHEI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGLDHFEFNNPEEYLCSKDLKDFIAKYHLDL
                     TYSNEHFNPRYAFGSQRDKDRHYNTPRAWIMQQYFNPEFLQDPRSFELPWCQRPDRKV
                     TIEDVKYVLSNHYQDTPYDPYGPEGTPTSRKSFRPIGINRTSQTAILHIRPNKPKEIA
                     AIQWMAYGSMPFNTIVPLFTQVKTIPDYFANTVENVSTDNFYWTNRLIAALADPHFKH
                     HEADLEDYLEKTMAKGHAMLHAVEAALVKGQPVDLEEANQGMSDDIQADTQALLNKIL
                     FDASNLMTNRFSLSD"
     gene            10985..12535
                     /locus_tag="TV193_001313"
     CDS             10985..12535
                     /locus_tag="TV193_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEL1513506.1"
                     /translation="MKKKYLLMMSVLGVFFAGQISQAKQVLADSKVKIVTTFYPVYEF
                     TKGVVGGEGNVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVPDMKKSL
                     TSKKVTVIKGTGDMLLVAGSGHSHEHDHDDADKKHDHDHDEEGHSHAFDPHVWLSPYR
                     SITVVETIRDGLSKAYPDKADHFKSNAAAYIEKLKELDKEYSDAFSAAKQKSFVTQHA
                     AFGYMALDYGLNQISINGVTPDTEPSAKRIAELSKYVKKYDINYIYFEENASSKVAKT
                     LAKEAGVKSAVLSPLEGLTEKDMKAGKDYFTVMRENLKTLRLTTDVEGKEILPEEDTT
                     KTVYNGYFKDKQVKDRKLSDWSGNWQSVYPFLQDGTLDQVWDYKAKKSKGKMTAAEYK
                     DYYTTGYQTDVSHIKINGKKNTMTFVRNGENKTFTYKYVGKKILTYPKGNRGVRFMFE
                     AKEPDAGEFKYVQFSDHAIAPGKAEHFHLYWGGDSQEKLHKELEHWPTYYDADLSGRA
                     VAQEINAH"
BASE COUNT         3729 a         2518 c         3007 g         3381 t
ORIGIN      
        1 gtttctctgt tattaaaata gttggagaaa atttatgaaa aaagtaataa atactattct
       61 attagctgct tgttttttat tctttttagg taattttact acaaatgtat tagctgaagg
      121 gataaatgat aaaatagaaa atggcactga aagcgatatt agcttccaaa atggtgaact
      181 cctaaaaaat tatcttatcc tagaaggtga acgagtatac tttgattatg atagagcaac
      241 tcaagataaa gtatcagatg atgttctaga gatgggaatg ttagttgaag ctataagtaa
      301 ggattattct gagaagacat tcaccccaga taaatatttt aaagctagtt ggcctatcca
      361 tggtaactat tgtggaccag gtcataatgg gaataacttt acgttgccag tagtagatgt
      421 tttggatcaa ggttgccaaa accacgatag ttgctataag tggggtgccg gtattggtgc
      481 taattgtgaa tgtaaccgtc agctcgttaa ttacataaaa gtttatagac gatggatgcc
      541 agcgaatgtc cttggcgtag ccgatgctat tagagtatat tttgagacag taggttctat
      601 aggatgttaa atttcaaaaa aaacgttagt gattattcga agtactatat tttgagtata
      661 gtgttattat ggataggaat gttctttgtt ccttgggata agactctatt cggtgtttcg
      721 atttatctgt ttgttatgca aaagttattt atagtgtttg gtttgacggc tatcttcatg
      781 gcctttgtgt ctaaaaaaat aaatctattt atttggggaa tattatttat tttcgcattt
      841 tggattaata tgtttttgtt attttccgta ttaccaattt tggggaatta gtttaacaaa
      901 aaagaagagg gggggttctc cctcttcttt tacgaataaa tagataagga ggtgctttat
      961 gctaacatac gacgaattta agcaggcagt tgataacggt tatatcacag gcgacacagt
     1021 cacgatcgtg cgtaaaaacg gacagatttt ggattatgtg ttgccgcatg aggaagtaag
     1081 gaacggggag gttgtgacag acgaaaaagt ggaagaggtg atgagagaat tagacaaata
     1141 aaaaagacct cgtccagaag tcggggaatt gtcggggaca acgtttgtaa atgtttctat
     1201 tccaacataa aacatttttt gatataatag gaaggatcat atgcaaagga gctgaaattg
     1261 gacaagcaca aaaggctcaa aacagtttta tatcaatgtg ccagcttggt cgtactgctt
     1321 tgtcttggag tgatgagcat gttttatctt gctgttcatg atcaatttga caagaaatca
     1381 aggttagccg agatagcaaa atcaagagct ggtgtcatct caattgatca tattgattgc
     1441 tatcatggca ctcagagcta cctcagtctt tttggaaaaa acaaggcagg caataccatc
     1501 atcgtcacaa tagaggagca atcagagcag ctcttgctta gtcgccctag caatggcatt
     1561 agtgctaagg aagcacagga aattgcctac catgccggag caaggactat tgaagcagtg
     1621 acatttggga ttgaaaacca caagaggatt tgggaggtgg ctgctcaaaa cggctactat
     1681 ctgattgatt tcaaaaccgc aaaagtgatc aaaaaggagg ttttatgacc aagctatcaa
     1741 ggcgcgtgtt agcaatggaa gaaagcgtca ccctagcagc aggtgctaga gcaaaggcac
     1801 taaaggctca gggacgcgat attttaagcc taactctggg agagccagat tttataacac
     1861 cgcagcatat ccaagaaaag gccattgagg ccatcaccac tggtaaggca agcttttaca
     1921 ctgttgcttc ggggttgcca gagctcaagg acgccattgc tgattacatg gcacgatcct
     1981 atggttatat tcctaccaga caggagattg tagtggggac aggcgccaaa tacgttttgt
     2041 atgccttttt catggctgtt ttaaatcctg gtgatcaggt gttgattccg actccttatt
     2101 gggtttctta tgctgatcag attaaaatgg tagacggggt accggtcttt gtacagggct
     2161 tggaggaaaa tcaatttaag gtcacagtag agcagctaga ggctgccaga actgatcaaa
     2221 caaaggttgt tttgatcaat tctccgtcca atccaactgg catgatttac agccgacagg
     2281 agcttgaagc cattggcaat tgggctgttc agcatgatat tctgatcctg gcagatgata
     2341 tctatggtgc attggtctac aatggcaatc aatttactcc aatatcagcc ttatcagagg
     2401 ctattcgtag acagaccatt actgtaaatg gcgttgccaa gagctatgcg atgacaggct
     2461 ggcgtttggg ctttgcggtc ggagacactg atattatcgc tgctatgggt aagattatcg
     2521 ggcaaaccac ctctaatgtg acaacagcgt cccaatatgc agcgattgag gcctttggcg
     2581 gtgaccaaac gtcagttgag gagatgagac aggcctttga agagcgcctc aataccattt
     2641 atcccctgct caatcaagtt cctggctttg aggctattaa gccccaagga gccttttatt
     2701 tctttcccaa tgtcaaaaaa gctatggaga tgaagggctt taccgatgtg acagccttta
     2761 ctgatgcgat cctagaagag gtaggactgg ctgttgtcag cggagctggc tttggtgctc
     2821 cagaaaatat caggctaagc tatgccactg atttggcaac cctaaaagaa gctatcagac
     2881 gactcaatca gttcatgaca actgacagca gccatgacaa caaagagaat gaatagaaaa
     2941 gagacattat gaccaaaaaa tacgtttcca ttatcgatgt taaagaccat gtaggacaag
     3001 aagtgacagt tggtgcttgg gtcgccaaca agtcaggcaa agggaaaata gcctttttgc
     3061 aattgcgtga tggctcagcc tttttccagg cagttgcctt taagccaaac ctgatccaag
     3121 cctttggtga ggaagcagga gcagctaagt ttgacacgat taggcatctc agccaagaaa
     3181 cctctgtctt agtaaagggc attgtcaaag aggacgctag atcaaaattt ggctatgagc
     3241 tagacattac ggacctagag gttattgggg attccaagga ttatccaatt actccaaagg
     3301 agcatgggac agactttctc atggatcacc gtcacctttg gctgcgctct cgcaggcagg
     3361 cagcaatcat gcaaatccgt aatgccatca tctatgcttc ctatgagttt tttgatcaaa
     3421 atggctttat caagtttgat agcccgattt tatcaggcaa tgctgctgag aacacaacag
     3481 agctatttga gacagattat tttggcaatc cagcctttct cagccaatca ggtcagctat
     3541 accttgaagc tggtatgatg gcgcttggtc gcgtctttga ctttggtccg gtatttcgtg
     3601 ccgaaaaatc aaaaacgcgc cgccatctga cagagttttg gatgatggac gcagaatacc
     3661 ccttcttatc ccatgaggaa tccttagacc tacaggaagc ctatgttaag gcgatgattc
     3721 agggtgtgct tgatcgtgct ccacaggcat tggagcttct agagcgtgac acagagctgc
     3781 tgaaaagata cattgcagag cccttcaagc gtgtctccta cgacgatgcg atcagcctgc
     3841 ttcaggagca cagcacagat gacgatgccg actatgagcc aattcagcat ggcgatgact
     3901 ttggctcacc gcatgaaacc tggatttcca attattttgg ggtcccaacc tttgtcatca
     3961 actacccagc tagctttaag gccttttaca tgaagccggt tcccggcaat gaagagcgcg
     4021 tgctatgtgc ggacctgcta gcaccagagg gctacggtga gattatcgga ggctcggttc
     4081 gtgaggataa ctatgacaaa ttgttggcga aaatcaaggc tgaaggccta aatcctgagg
     4141 attatgactt ttaccttgac cttcgcaaat atggctcagt gccgcatgct ggttttggac
     4201 ttggactaga gcgcatggtg acctttgttg caggtaccaa gcacattcgt gaggctattc
     4261 catttccacg catgcttcat cgcttaaaac cataatgaac cctatcagcg tccgccattg
     4321 ggcgcttttt tgctgcgctg agcagtactt agagctcaag cctcccagtt agacttggca
     4381 gagctgtggc tctttgcttg agctattgta ggcaaaggta tcactggatc tgaaaacaac
     4441 aaaatcagac aagtgatatc aaaattaaaa aaaaaaaaaa acgaaaccta ggaggatcgg
     4501 tgagcttatt agtttggcac taatcatcat tatgctataa ttgtcttcac aaataattta
     4561 gaaatagctc atatttctat cattaaagga gagagatgat gaatcgtaaa aagcatacca
     4621 aactcattcg tcactacagt atctgctcag cagtggctgt cctagcagca gttagcttgg
     4681 gaacaggtca ggacgtacag gcttcggaac ccaatccata tccagatgtg aggcgtttcc
     4741 ttgatgagaa gtacgatgga gatgtggata aattatctaa acaacttcaa ggttattttg
     4801 gtagtttaag agagtatata gagtttgaac ttaaaaatgg caaacaaggt cctgctggcc
     4861 ctcaaggccc aaagggtgat aaaggagacc ccggagagcc aggtcctcaa ggtccagtgg
     4921 gccccgctgg tccaaagggt gatcgtggtt tagacggacg acgtggccca gcaggtcagc
     4981 aaggggaagt cggcccagtt ggtcctcagg gtcctcaagg cgagcaaggg ccaaaaggcg
     5041 accgtggcga acaaggacca aagggtgaac gcggtgagca aggaccaaag ggtgaacgcg
     5101 gtgagcaagg gccaaaaggc gaccgtggcg aacaaggacc aaagggtgaa cgcggtgagc
     5161 aaggaccaaa gggtgaacgc ggtgagcaag ggccaaaagg cgatcgtggc gagcaaggac
     5221 caaagggtga acgcggtgag caagggccaa aaggcgatcg tggcgagcaa ggaccaaagg
     5281 gtgaacgcgg tgagcaaggg ccaaaaggcg atcgtggcga gcaaggacca aagggtgatc
     5341 gtggcgagca aggaccaaaa ggtgatcgtg gcgaacaagg accaaagggt gatcgtggcg
     5401 agcaaggacc aaaaggtgaa cgcggtgagc aaggaccaaa aggcgatcgt ggcgagcaag
     5461 gtccaaagaa ggagccagaa aaagacacca agccatcagt gccaaaggca ccagataata
     5521 tggctgcacc aaaggctccg gagaagaaga accctaaagc accggctcct aagtcagctc
     5581 caaaggcatc attgccatca acaggagaca ctagccaatc atttgttgca gcagcccttg
     5641 gctttatcgc tagcgcgggc ttgctagtct tcaaaagaaa gaaaaactaa gctagctaaa
     5701 gactgtaaac aagcctcaac tgttacagca agcctctttg acatcttgca gataagagga
     5761 tttcttagcg aatgaagtgt gtctaaagtc agatactctg ctggactagc agtagctgat
     5821 ctccctgaaa atcagttatg ctaaagcatt gagccttagt tgcaaggctt aggtgtgacc
     5881 ttccaaagga agctgctttt gcctgtatca ctttaggaag atatctaaaa gagacacttt
     5941 tttcacgctg aagctaagct agcttttcct atgacaaata tcctataaca ataaactcca
     6001 aacaaaagag aggtcaaatg gtacctctct tttacttagc tttaggattg atagattcta
     6061 aaggcttcct tgtttcttga tcaagaagtc cttactgata gagtctgtct tagccgggct
     6121 tatatggtat aatacctaat ggagataaga aaagtcctta acaaatagag tttcatctat
     6181 tgttacagga gcaaccaagt gaaaggagat gctacatgtc agataaacaa atcaatttgg
     6241 ttattgttac aggaatgagt ggcgccggca aaacagttgc cattcaatca tttgaggatt
     6301 tggggtattt tactgttgat aacatgccac cagctttagt gcctaaattt ttagagctgc
     6361 ttgagaggac caatgaaacc caaaaggttg ctctggtagt ggatatgcgc agcagacgct
     6421 ttttcaagga gattaactct atcttagatc atattgagct aaatgccaac ctcaagctac
     6481 ggatcctctt tcttgatgcg actgatagtg agctagtgtc acgctataag gaaactagaa
     6541 gaagtcaccc tctggctgct gatggtcggg tgcttgatgg gattcgacga gaaagagagc
     6601 tgttagtccc gcttaagagc atgagtcagc atgtggtcaa taccaccgat ctaaccccaa
     6661 gacagctgcg taaggtgatt tcggatcagt tttcaagcga gtcagaccaa gcctcattta
     6721 gaattgaggt gatgagcttt ggctttaaat atggcctccc cttagatgcg gaccttgtct
     6781 ttgatgtgcg ctttttgcct aatccttatt atcaggtggc gctaagagag cagacagggc
     6841 ttgatcaggc tgtttttgat tatgtgatga ctcatcaaga gtcagaggcc ttttataatc
     6901 atttgttagg cttgattgtt cctattttgc ctgcttatca aaaggaaggc aaatcagtgc
     6961 taaccattgc tattggctgt acaggtggtc agcatagaag cgtcgccttt gcccatcgct
     7021 tggcccaaga cttgacagca gactggccgc tgcatgagag tcatcgggac atcaatcgtc
     7081 gtaaggaaac ggtaaatcgc tcatgagaaa tcctaaaata acggtgatag gaggaggaac
     7141 aggtattcct gttatcctaa aaagccttcg caaggaggcg gttgacatta ctgcggtggt
     7201 cactgttgct gatgatggtg ggtcatctgg taagctgcgc aatgccatgc agcttacccc
     7261 gccaggtgat ttgcgcaacg tcttgttggc catgagtgac atgcctaagt tttatgagcg
     7321 tgtgtttcag tatcgtttta atgaggcaga tggtgctcta gctggtcatc ctctaggcaa
     7381 tttaattatc gcaggtattt ctgagatgca gggatccacc tataacgcta ttcagatttt
     7441 gacgaaattt ttccatatca ccggcaagat ttttccctca agcgagcagc ccttgacact
     7501 gcatgctgtc tttaaggacg gtcatgaggt gtcaggagaa agctctattg ccagctacca
     7561 aggcatgatt gaccatgtct atgtgaccaa tacctacaat gatgacctgc caaaggccag
     7621 tcgtaaggtg gttgaggcca ttctccaaag tgatatgatt gtgcttggtc ctggttcctt
     7681 gtttacctct attttgccca atcttgtaat tccagagatc aaagaagccc tgagagtaac
     7741 caaggcagag gtggtttata tttgtaacat tatgacccag tacggtgaga cagagcaatt
     7801 ttccgatgcg gatcatgttg cggttttaaa tcagcatctg ggcagggact taattgacac
     7861 tgttttggtt aatgttgagc aggtgccaaa aagctatatg aattccaacc aatttgacga
     7921 atatctggtc caagtagagc atgactttgc aggtctgtgt aagaccgcaa agcgtatcat
     7981 ctcgtctaat tttctgcgtt tggagaatgg cggagccttt catgacgggc acttggttgt
     8041 agaagaatta atgaacctag ttaggataac caagctatga gttttacgac aactgttaaa
     8101 gaagaattga ttcatttatc tgcttctgat caaacagaat tatcagcaat catcaagctg
     8161 gctggtagcc taggcttggc taatcagagc ttgaatttgt ctatcacaac tgaaaacgct
     8221 aagattgctc gctacatcta tgcgcttatc gaagacacct atcatatcat tccagaaatc
     8281 aggtaccatc aaaagaccaa cttgaaaaaa aatcgtgtct atacggttta tttggataag
     8341 caggtggata agctcttagc agatttaaag ctggcagatt ctttttttgg cattgagaca
     8401 ggtattgagc agcaggtcat gtcagatgat gatgctggtc gggcctatct caagggtgct
     8461 tttttagcgg cagggactgt aagggatcca gaatccggca agtatcagct agagatctac
     8521 tctgtctatc tagaccatgc tcaggatttg gcccagctca tgcacaaatt catgctagat
     8581 gccaaggtta tcgagagaaa aaatggtgca gtaacctatt tgcaaaaggc tgaggacatc
     8641 atggattttc tcattattat tggtgccatg tcgtgtaagg aggagtttga ggctgttaag
     8701 cttttgcgtg aggcgagaaa tgacatcaat cgggccaata atgcagagac tgctaatatt
     8761 gctaaaacca tcaccgccag catgagaacc attaataata ttatcaaaat catggatacg
     8821 attggcttag acagcctgcc agttgagctg cagcagattg cccagatgag agtagccaac
     8881 ccagactatt ctcttcaaca aatcgcagat tcgcttgact ttgccatcac taagagtggg
     8941 gtcaaccatc gcctgcgaaa aatcaataag ctggcagagg atttataaag acagcttagc
     9001 ctttttcagg ctgataaaaa agggggtaag gtgatacgaa caagccgcct tttaaggcat
     9061 gccttgttga gctttctcta ggctgttgat ggagtgatct caaggcgctt ttgttactgt
     9121 cattccaaca ggctatctga ttttgggatg acttcttact aataagcttt tctaatggct
     9181 ggctgacaac gattagcgat atagttaagg cttatcgtga ttcaacaaga ggctttagtc
     9241 tcttttttgc ttgtcagaat tattttttta ggcttttctt acaaatgaga ggacaatgtg
     9301 acaatctgtg gtatgatatt agtaatgaat acaaaggaga acaaatcatg tcatgcacaa
     9361 ctattcttgt cggtaaaaaa gcgacctatg atggatcaac aatcgttgct cgtacagagg
     9421 attcacaaaa tggggaattt acccctaaaa aaatgacagt tgttagacca aaagaccaac
     9481 ctagacacta tcaatctgtc ttgtctagct ttagcatgga gctgccggat cagccgatgg
     9541 cttatacctc ggtgcctgat gccctaggaa aggacggtat ctggggagaa gcaggtgtca
     9601 ataccctcaa tgttgctatg tcagcaactg agaccattac ttcaaatgct cgcgttcttg
     9661 gagcagatcc tcttgtttcc tctggtattg gagaagagga catgctgacc ttggtgcttc
     9721 cttatattcg gtctgcaaga gagggtgttc ttcgtttggg agctatccta gaagcatacg
     9781 gtacctatga ggctaacggt gttgcctttt ctgatgagca tgagatttgg tggctggaaa
     9841 caataggtgg tcatcattgg attgcaaggc gcgttcctga tgatgcttat gtcactaatc
     9901 ccaaccagtt tggccttgat cactttgaat ttaacaatcc agaggaatac ctgtgttcca
     9961 aggatttaaa ggactttatt gccaaatatc atctagattt gacctatagc aacgagcatt
    10021 ttaaccctcg ctacgccttt ggtagccaaa gagataagga tcgccattac aatacaccac
    10081 gcgcttggat tatgcagcaa tactttaatc cggagtttct gcaggatccg cgcagctttg
    10141 aacttccttg gtgccaaaga cctgatcgca aggtgaccat tgaagacgtt aagtacgtgc
    10201 ttagcaatca ttatcaggac accccttatg atccttacgg cccagaggga acgccgacta
    10261 gtcgaaaatc ctttaggccg attggtatta accgtacgag tcaaactgct attttacata
    10321 tccgtcccaa caagcctaag gaaattgctg ccattcagtg gatggcctat ggttcgatgc
    10381 cctttaatac aatcgttccg ctattcaccc aggtcaagac cattccagat tattttgcaa
    10441 acactgttga aaatgtttcc acagacaatt tctattggac caatcgcttg attgcagccc
    10501 tggctgatcc tcacttcaag caccatgaag cagatttgga ggactatctc gaaaaaacaa
    10561 tggccaaggg tcatgccatg ctgcatgctg ttgaagcagc gctagtaaaa ggtcagccgg
    10621 ttgacctaga agaggccaac caaggcatga gtgatgacat tcaggcagat acacaggctc
    10681 tgctcaataa gatcctcttt gatgctagca atctcatgac caaccgcttt agcctaagcg
    10741 actaagtaat ctcaatagtc aaacgagctc atatcattat agatatgggc tcttagcttg
    10801 aaaaggatag tagagcggtc ttatagtcag actaattaat ggtaacgatg agtccagtta
    10861 aggtaaaaaa agagcactta gctaatgcaa aaaaagtaaa aaacttgcaa aagaatgata
    10921 ttgtgttata cttaaccagt aaatattaag agctatttgc gatatgatat atagaggagg
    10981 aatcatgaaa aagaagtatc ttttaatgat gagtgtgctc ggtgtctttt ttgcgggaca
    11041 gatcagtcaa gcaaaacagg tcctagcaga tagtaaggtc aaaattgtta ccaccttcta
    11101 tcctgtttat gaatttacca aaggcgttgt cggaggtgag ggaaatgtgt ctatgctgat
    11161 gaaagcagga acagagcctc atgattttga gccgtcaaca aaggacatca aaaagatcca
    11221 agatgccgat gcctttgttt atatggacga taatatggaa acttgggtcc ctgatatgaa
    11281 gaaatcactg acttctaaga aggttacggt gattaaggga acaggagata tgctattggt
    11341 agctggctct ggtcacagcc acgagcatga ccatgacgat gccgataaaa agcatgatca
    11401 tgaccacgac gaggaaggac acagccatgc ttttgacccg cacgtatggt tgtcacctta
    11461 tcgcagcatc accgttgtcg aaacaattcg tgatggtcta tctaaggcct atcctgacaa
    11521 ggctgaccac ttcaaatcta atgccgctgc ttatattgaa aagctcaagg aattagataa
    11581 ggagtatagt gacgcttttt cagctgccaa gcaaaagagc tttgtgactc agcacgcagc
    11641 ctttggttat atggcgcttg attatggctt gaaccaaatc tcaatcaatg gtgtcacacc
    11701 agatacggag ccttcagcta agcgcattgc agagctatca aaatacgtca aaaaatatga
    11761 cattaactac atttattttg aagaaaatgc ttcaagcaag gttgccaaaa ccctagccaa
    11821 ggaggctggt gtcaaatcag ctgtccttag tccgcttgaa ggcctaactg aaaaggacat
    11881 gaaggccggc aaggattact ttaccgttat gcgtgaaaac ctcaaaaccc tacgcttaac
    11941 aactgatgta gaaggaaaag aaattcttcc agaagaggat accactaaaa ctgtttataa
    12001 tggctacttt aaggataagc aggtcaaaga ccgcaaattg tctgattggt ctggtaactg
    12061 gcagtctgtt tacccattcc ttcaagacgg tacattagat caggtatggg actataaggc
    12121 taaaaaatct aaaggaaaaa tgaccgcagc tgaatacaag gattattaca ccactggcta
    12181 tcagacagat gtcagtcata tcaagattaa tggtaagaaa aataccatga cctttgttcg
    12241 taatggtgaa aataaaacct ttacttataa gtacgtcggt aaaaagattt tgacctatcc
    12301 aaagggcaat cgtggcgtgc gcttcatgtt tgaagctaag gagccagacg ctggtgaatt
    12361 taaatatgtt cagttcagtg accatgctat cgcaccaggt aaggcggagc atttccacct
    12421 atactggggt ggtgacagcc aagaaaagct tcacaaagag ctagagcatt ggccaactta
    12481 ctatgatgcg gacctatcag gtcgtgccgt tgcccaagaa atcaatgctc attaaccact
    12541 caaaagacta ggcagttcaa tcggcctagt tttttcttgt cttagttgct gtataggacc
    12601 taaatgctga tagctggtct taagatttat tttta
//
LOCUS       DARYXS010000056        12573 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.057, whole genome shotgun sequence.
ACCESSION   DARYXS010000056 DARYXS010000000
VERSION     DARYXS010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12573
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.057"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            22..192
                     /locus_tag="TV193_001314"
     CDS             22..192
                     /locus_tag="TV193_001314"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513507.1"
                     /translation="MLRYLKAILYLLAPRLAFSVTGVLFPDVFDNLFLVYNILMTLAF
                     WLAIYSVDLPEK"
     gene            complement(854..1012)
                     /locus_tag="TV193_001315"
     CDS             complement(854..1012)
                     /locus_tag="TV193_001315"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513508.1"
                     /translation="MACYSGRVKKLRQVAARSEWVVVPMGDSSTANKMEEAKKLAAFE
                     ATQTLFKL"
     gene            1100..1170
                     /locus_tag="TV193_001316"
     tRNA            1100..1170
                     /locus_tag="TV193_001316"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1132..1134,aa:Thr,seq:ggt)
     gene            1698..1952
                     /locus_tag="TV193_001317"
     CDS             1698..1952
                     /locus_tag="TV193_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEL1513509.1"
                     /translation="MSYEQDFLRDFEDWVKAQIQVNQLAMATSRQIAKEDNDQRARDA
                     FIRYESKLDAYEFLLGKFDNYNKGKAFHEVPDSLFGSRHY"
     gene            1974..2474
                     /locus_tag="TV193_001318"
     CDS             1974..2474
                     /locus_tag="TV193_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1513510.1"
                     /translation="MARRYNRKKQYKLQLKRQGLLKAVINQVEQTVEKVVDKTKEAVH
                     TASQMVTASKTETADLQDKQSIAEKAAQPKADVASSSLADSSEVSSEKEASKASSEVL
                     SRDAFAELAEVSELRADIVTVLFEAGIRSAAAFSQWTEAELLALKGIGPATISKLKEN
                     GVNFKK"
     gene            2734..3318
                     /locus_tag="TV193_001319"
     CDS             2734..3318
                     /locus_tag="TV193_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1513511.1"
                     /translation="MIEIMGSVENNRLPDVKTSRLLLRQRTLADVEAIFAYASRPEVS
                     YPAGFPPVKTLEEEEHYIANTMPKRWLLQQLPAGYGIALKGDNRIIGSVDFNNRHADD
                     VFEMGYLLHPDYWHQGIMTEAASALLEVAFTLLKLHKVEISCYDYNMGSRRIAEKLDF
                     TLEATIRDRKDAKGNRCADLRYGLLKREWERQCR"
     gene            3518..4081
                     /locus_tag="TV193_001320"
     CDS             3518..4081
                     /locus_tag="TV193_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1513512.1"
                     /translation="MNIILIGAQASGKMTIGQELEKLTDLTLFHNHESIDFVTKFIPM
                     SSEARELIDELRLLFFKTFAKRQQSIIFTVVIDFNAPEDIAFLETLQSVFHDFDREVL
                     FVELEIDLKERLRRNKTENRLYHKPIKRHLEWSEKDILDTAKFANFNPAKVPENLKYY
                     CKINNTSLSAQETAQFIVQKMKELEVS"
     gene            4094..6745
                     /locus_tag="TV193_001321"
     CDS             4094..6745
                     /locus_tag="TV193_001321"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEL1513513.1"
                     /translation="MSKELSPKYNPAEVEAGRYQAWLDQDVFKPSGDKKAKPYAIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     ISRYDLGRDKFLDKVWEWKDEYAATIKEQWGKLGLSLDYARDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDSAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGQHVVLPIVNKLIPIVGDEHADPAFGTGVVKIT
                     PAHDPNDFEVGGRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKAVVAKLEEIGALV
                     EIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGDMYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPDVDSEDFQRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRKPFSNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQASANVEQVASGAAGNVTDCWILHNLNETIGKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTADYPTVDPAFENEAAHKGVESLKDLIRTVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPERLKIASSIVTPELAMSA
                     VITGAEIFLPLADLLNVTEELARLEKELAKWQKELDLVSKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVERIKEMEKLVR"
     gene            6958..7446
                     /locus_tag="TV193_001322"
     CDS             6958..7446
                     /locus_tag="TV193_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HEL1513514.1"
                     /translation="MTTAATKASVPHKEKMESKEPETSHQPEAYPDLASYQELAVHVS
                     IADQVMTIIGDGKVIFKTSVSTGAKESPTPTGTFVIEPERGDFFFNQASEEGAYYWVS
                     FKDHGIYLFHSLPTDQYGNEIPEEAERLGQPASHGCVRMSRADAKWFYDNIPEGISVT
                     IE"
     gene            complement(7649..8449)
                     /locus_tag="TV193_001323"
     CDS             complement(7649..8449)
                     /locus_tag="TV193_001323"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513515.1"
                     /translation="MKKKLVMSLIVNLPLLSLICFNEVSANSDYENSPVLGQGYYGYD
                     DYTEAPQIGDQKVIGFRRDWENARDFGVKPIKNNDKEIVVKTSPGSLIRIFKVEEDDK
                     ETELVQVQKKSNGDLTNNRYYPIAKWDGKIVFSLESARTQKTNSKEETYVPYNKIASN
                     GDKFRVHITSDGFVLGSEIWIVGESKPQDIIEQEQKKAQKELEEQKKQENLRQQIKKE
                     REHSQKRVVENIYLKEIRENAHKSWHKRLNEKIQEQWSKFTVFLNKYY"
     gene            8960..9196
                     /locus_tag="TV193_001324"
     CDS             8960..9196
                     /locus_tag="TV193_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEL1513516.1"
                     /translation="MTFEEILPGLKAKKKYVRKGWGGAENYVQLFDSIEQNGVALEVT
                     PYFLINVSGAGEGFSMWAPTPCDVLATDWVEVYD"
     gene            9189..9887
                     /locus_tag="TV193_001325"
     CDS             9189..9887
                     /locus_tag="TV193_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEL1513517.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLRNGFTVYGVDKAKKPDLSGDF
                     QFLQLDITGDLAELFEAVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVR
                     ITRHYLAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGI
                     QVFGIAPGAVQTAMTATDFEPGGLAQWVADETPIGRWLRAEEIAELTMFLASGKASAM
                     QGEIVKIDGGWSLK"
     gene            10087..10545
                     /locus_tag="TV193_001326"
                     /pseudo
     CDS             10087..10545
                     /locus_tag="TV193_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
     gene            10546..11520
                     /locus_tag="TV193_001327"
     CDS             10546..11520
                     /locus_tag="TV193_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1513518.1"
                     /translation="MKLALVGTGMIVKEVLPVLKEIKSIDLMAIVSTPRSLETAEALA
                     DAFGIQQASCQLAEVLKNEEVDTVYVATPNHLHFEVAKQALEAGKHVICEKPFTMTAK
                     ELDALSSIARAKQLILLEAITNQYLPNTQFIKDHLTELGEIKLVECNYSQYSSRYDAF
                     KRGEIAPAFDPKKGGGALRDLNIYNIHLLVGLFGKPQTVQYLANMERQVDTSGVLLMD
                     YERFKAVCIGAKDCSAEIVSTIQGNKGFLSVLGAPNAVPELLLAIRGEQARTVNFNHP
                     SHRMYDEFIAFSDIISNKDMERAEQALEHSKAVMAVLEQAAASLESDS"
     gene            11876..>12573
                     /locus_tag="TV193_001328"
     CDS             11876..>12573
                     /locus_tag="TV193_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEL1513519.1"
                     /translation="MPNYAIILAAGKGTRMKSGLPKVLHKVSGLSMLEHVLNSVSALA
                     PQKQLTVIGHQAEQVRAVLGDQSLTVVQEEQLGTGHAVMMAEEELSGLEGQTLVIAGD
                     TPLIRGESLKALLDYHIREKNVATILTANAKDPFGYGRIIRNVAGEVVNIVEQKDANE
                     AEQEVKEINTGTYIFDNKRLFEALKHLTTDNAQGEYYLTDVISIFKAGQERVGAYLLK
                     DFDESLGVNDRLALA"
BASE COUNT         3635 a         2399 c         2953 g         3586 t
ORIGIN      
        1 tagaaacaga ggtaatggta gatgttaagg tatttaaaag cgattttata tctattggct
       61 cccagattag ctttttcagt aacaggtgta ttatttcctg atgtttttga taatttattc
      121 ttggtttata atattttaat gacacttgct ttttggcttg cgatttattc tgttgacctc
      181 ccagaaaaat agttgcggga cttgtttagt agttggttaa caaagggtag atgatcagtt
      241 aaaggtgaag cgtctgagct atgttggcca ttatgcgtac agctggcaaa atgcttttga
      301 tccaatcggt taaacctcaa gctattctct ttgggataac aaatacccca tctgtctcag
      361 acaaagaatg gcaacgccta aataggatta acatctgcaa gtgctcttgg gactgccaat
      421 gctcttagta gcataggtga tttttcagcg ctagagactt ttcagcagat gagaaatagt
      481 cgcaataaac gaagacaaaa agacttggct tgagctcgta tttggcctta aaatagtagt
      541 cagtcgagct taaaaaaaag tcattgcagc ttatgaaggt tatcgtatcc ttatttcaac
      601 tgagctaggt aagctaggga gtttccttta ggtgtaacga tagaagcgat caaataatta
      661 cttcatttaa agataaggat tgtaataagc atagaaaaga gcagttactt gacataacta
      721 ctcaatgtaa aaccgtttca ggcggtggct tttgttatta gataaaaaat aatcgtcatc
      781 attcggccaa agttagaacg gttatgtttt atgctcatct ttgaagatgt tatagcacaa
      841 gccaataggg agactaaagc ttaaaaagag tttgagtagc ttcaaaggct gctagctttt
      901 tggcctcctc cattttgtta gctgttgatg aatcgcccat aggcaccacc acccactcag
      961 aacgagcagc cacctgtctt aattttttta ctctaccact gtagcatgcc acaagaaaaa
     1021 atcagaacac taatgacatt taaaaaaaaa aaaaaaaaga cttgcacacc aaaacaagtt
     1081 atagtatcat agaaaggtag ccgctatagt taaatggtat aataaagcaa tggtaatgct
     1141 tcgttccgag ttcgattctc ggtggtggca tctgagtact gtcctaagtc ttattaggac
     1201 ggttttttta ttgctaggtg aaccaatagt agtcatctgt gaatcattac catagtggct
     1261 tctgttcgcc caagcatagc aaagctgctg tcagaatgaa cccagccaac aatgtcaata
     1321 gaagcagcac cagacaagcc tttagtcacc catgctttaa agattttacg gctgtaatgt
     1381 tagtaactgt tacctgtttt gttcaagttg tctgtgacat caaatcactt gatgctacca
     1441 gtactgtcaa tacattagct gtcacttggc agttgttctg actactacta aaaatagcag
     1501 ctatcagcgt tgcaatcaaa aaagaatgcg aatcaagctc tcctgatcag cttaactttt
     1561 tgaaagagtt tgtacgggtc aagcatcagc aagtcagact gccttatttg tttttatcat
     1621 aagcttctaa gaaaatagca caataagcca ggctgtggta taatggtaag gattaagtca
     1681 gaaagagggg ggcagacatg tcttatgagc aagacttttt gagagatttt gaagactggg
     1741 tgaaggctca aattcaggtc aaccagctag ctatggcaac gagccggcaa attgcaaagg
     1801 aagataatga tcaaagagcc agagatgcct ttattcgtta tgagagtaag ctagatgctt
     1861 atgagttttt attaggaaaa tttgataatt ataataaagg taaagctttt catgaggtgc
     1921 cagacagcct atttggtagc cgtcattatt agaggaaggg ataagcagta atcatggcaa
     1981 gacgatacaa tcgtaaaaaa caatacaagc tacagcttaa gcgtcaagga ctgctcaagg
     2041 cagtaatcaa tcaagtggag cagactgtgg aaaaggtggt tgataagact aaagaagcag
     2101 tgcataccgc ttcacaaatg gtaacagcat caaagacaga gactgctgat ctacaggata
     2161 agcagagcat tgctgaaaaa gcagctcagc ctaaagcaga tgtagcttct agtagcttgg
     2221 ctgacagttc tgaggtttca agtgaaaaag aggcctcaaa ggctagcagt gaagtcttat
     2281 cacgcgatgc ttttgcagag ttggctgagg tttcagagct tcgggcagat attgttacgg
     2341 tgctttttga ggctggtatt aggtcagctg ctgcttttag ccaatggaca gaggcagagc
     2401 ttttggcgct taagggaatt ggaccagcga ctatcagcaa gctaaaggaa aatggtgtca
     2461 actttaaaaa gtagtctgat ttttattgct taataagtat aaatttgtta gaatgttagc
     2521 aatcagaggt atcttgagtt tgtctgttac agagagcggt ggtgttgaga aatccgcaca
     2581 gatgtcaagt tatgtagctg aggcttacaa tggaaaaatg ataaagcagc agattaagtg
     2641 taatctgaaa cagtggtggt accgcggatt attagtgaat tcgtccctgt ctagtcgatt
     2701 gactaggcgg ggttattttt tggaggactt gctatgattg agataatggg ttctgttgag
     2761 aataatagat taccagatgt caaaactagt cgtttgctgc tgcggcagcg tactttagct
     2821 gatgttgaag cgatttttgc ttatgctagc cgacctgagg ttagttaccc agcaggcttt
     2881 ccacctgtga aaacccttga agaagaggag cattacatcg caaacacgat gcctaagcgc
     2941 tggcttttgc aacagctgcc ggcaggctat ggcattgccc taaagggtga caataggatt
     3001 attgggtctg ttgattttaa caaccgtcac gcagatgatg tctttgaaat gggctatctg
     3061 ctccaccctg attattggca tcaggggatt atgactgagg cagcgagtgc cctgctagag
     3121 gttgccttta ctctgcttaa gcttcataag gttgaaatca gctgttacga ttacaatatg
     3181 gggagtcgtc ggatcgcaga aaagctagac ttcactcttg aggcgaccat tcgtgatcgc
     3241 aaggacgcta aaggcaatcg ctgcgcagac ttgcgctatg gactgttgaa aagagaatgg
     3301 gagaggcagt gtagataagg agtagactct ctaaaatatg cgttaatctg tcaaaagcat
     3361 ttcataagaa gtcctcaaac tcaaagcgct tatgactacc aaaactggtt agcgcttcgc
     3421 caaccagtgt catcagtttc tggtagtctg ccttgagcag caagtgttat gttaagtgag
     3481 gtgagaagag gtaagagaga tcggaaagag gtttggtatg aatattatct taattggagc
     3541 acaggcgtct ggtaagatga caattggaca ggaattagaa aaactgactg acctgacttt
     3601 atttcataat catgaatcga ttgattttgt gactaagttt ataccaatgt catcggaagc
     3661 tagagaacta attgatgagc tacgattgct attttttaaa acatttgcaa aacgtcagca
     3721 atcaattatt tttactgttg tcattgattt taatgcacct gaagatatag cgtttttgga
     3781 aacactacag agtgtgtttc atgatttcga cagagaggtt ttattcgttg aattagaaat
     3841 agatttaaaa gaacgcttaa ggcgaaataa aactgaaaat cgactttacc acaaaccgat
     3901 aaagcgtcat ttggagtggt ctgagaaaga tattttggat actgctaaat ttgctaactt
     3961 taaccctgca aaggtaccag aaaatcttaa atattattgt aaaatcaata atacgagtct
     4021 ttctgctcaa gaaacagcgc agtttatcgt ccaaaaaatg aaagagttag aagtaagcta
     4081 gaaaggacac catatgtcaa aagaactttc acccaaatac aatccagctg aggttgaggc
     4141 tgggcgttat caagcttggc tggaccaaga tgttttcaag ccatcaggcg acaagaaggc
     4201 taagccgtat gctatcgtga ttccaccgcc aaacgttaca gggaagctgc accttggtca
     4261 tgcttgggac acgacccttc aagatattat tattcgtcaa aagcgcatgc agggctttga
     4321 tactctctgg ttgcctggta tggatcatgc aggtatcgcc actcaggcta aggtcgagga
     4381 gcgcttgcgc gagcagggga tttcccgtta cgatctcggt cgtgacaagt tcttagacaa
     4441 ggtttgggaa tggaaggacg agtatgcagc aaccatcaag gagcagtggg gtaagcttgg
     4501 gctttcacta gactatgcgc gagatcgctt cactcttgat gaggggctct caaaggctgt
     4561 tcgcaaggtt tttgttgagc tttacaagaa aggctggatt taccgcggtg agttcatcat
     4621 caactgggac tcggcagcta ggacagctct ttcagatatc gaggttatcc ataaggacgt
     4681 tgagggtgcc ttctaccaca tgaactatat gctagaagat ggttcgcgcg cccttcaagt
     4741 agcaaccaca cgtcctgaaa ccatgtttgg agatgtggct gtcgctgtca atccagaaga
     4801 tcctcgttac aaggacttga ttggtcaaca tgttgttctg ccaatcgtga ataagctgat
     4861 cccaatcgtt ggagacgagc atgcggatcc ggcattcgga acaggggttg ttaaaatcac
     4921 accagcccat gacccgaacg actttgaggt tggtgggcgt cataatctcc cacaggttaa
     4981 tgtcatgaat gatgatggta ccatgaatga gcttgcaggt gaatttgcag gtatggatcg
     5041 atttgaagct cgtaaggctg ttgtggctaa gctagaagaa atcggtgccc ttgttgagat
     5101 tgaaaagcgt gttcattcag taggtcattc agagcgtaca ggtgttgtgg ttgagcctcg
     5161 cttgtcaaca cagtggttcg tgaagatgga ccaattggct aaaaatgcta ttgccaacca
     5221 agacacagat gacaaggttg acttctaccc accacgcttc aacgatacct tcttgcaatg
     5281 gatggaaaat gtccacgact gggtaatctc tcgtcagctt tggtggggac atcagatccc
     5341 tgcatggtac aacgaagcag gtgacatgta tgttggtgag gaagcgccag caggtgatgg
     5401 ctggaagcag gacgaggatg tccttgacac ctggttcagc tctgcgcttt ggccattttc
     5461 aactatgggc tggcctgatg tagactcaga agatttccaa cgttacttcc caacgtcaac
     5521 attggtaaca ggttacgaca tcatcttctt ctgggtgtct cgtatgattt tccaatcgct
     5581 tgaatttact gggcgtaagc ctttctctaa cgttcttatt catggtctga ttcgtgacga
     5641 agagggacgc aagatgtcta agtcgcttgg aaatggcatt gatccaatgg acgttatcga
     5701 aaaatatggt gcagatagcc tacgctggtt cctatcaaat ggctcagccc ctggtcagga
     5761 cgtgcgcttc tcctatgaaa aaatggatgc gtcctggaat ttcattaaca agatttggaa
     5821 catttcacgt tacattctca tgaataatga gggcttgaca cttgagcaag caagtgcaaa
     5881 tgttgagcaa gttgcgtctg gcgctgctgg aaacgtgaca gactgttgga tcctccacaa
     5941 tctcaatgaa acaatcggta aggtcacaga gaactttgat aagtttgagt tcggtgtggc
     6001 aggtcatatc ctctacaatt ttatctggga agaatttgcc aactggtatg tggagctgac
     6061 caaggaggtt ctgtacagcg acaacgaaga cgagaaggtt atcactcgct ctgttctcct
     6121 ctacacgctg gataaaatcc tgcgtctcct tcacccaatc atgccgtttg tgacggaaga
     6181 aatctttggt caatacgctg aaggttctat cgtgacagcg gactatccaa cggttgatcc
     6241 tgcttttgaa aatgaagctg cgcacaaagg cgtggaaagt ttgaaggact tgattcgtac
     6301 ggtgcgaaat gcgcgtgcgg aggttaatgt agcaccaagt aaaccaatca ctatccttgt
     6361 caaaacaagc gatagcgacc tggaagcctt cttcaacagc aatgtcaact acatcaaacg
     6421 cttcacaaat ccagagaggc ttaagattgc ttcaagcatt gtgactcctg agttggccat
     6481 gtcggctgtt attacaggtg cagaaatctt ccttccccta gctgatctgc tcaatgtcac
     6541 agaagaatta gctcgccttg aaaaagaatt agctaagtgg caaaaagagc ttgacctggt
     6601 cagtaaaaag ctcagcaatg aacgcttcgt tgctaatgcc aagccagaag tcgttcaaaa
     6661 agaacgcgac aaacaggctg attaccaagc taaatacgat gcaaccgtag agcgcatcaa
     6721 ggaaatggag aagttagtaa ggtaggatag tgatcatcta agagccaatt ggctcttttt
     6781 ttgatatact gtcaaggagt aatcatcaca attatctata taagtcaaag gagtgtctca
     6841 tgaaaaaaag agtcattggt tggttaggtg tgctggtaat agggcttatg cttggtctga
     6901 tatggtggaa atggttagtg gcagatcggc cactaaccca agcaggtcaa ggaagtcatg
     6961 accacagcag cgacaaaggc ctcagtgccg cataaggaaa aaatggaatc aaaagagcct
     7021 gagacatcac atcagccaga agcctatcct gatcttgcta gctatcagga attggctgtt
     7081 catgtgtcga ttgcagacca agtcatgacc attataggag atggtaaggt tatttttaag
     7141 accagcgtgt caacaggagc aaaggaaagt ccaacaccga cagggacctt tgtcattgag
     7201 cctgagcgag gagacttttt cttcaatcag gcatcagaag agggagctta ttattgggtg
     7261 tcctttaagg accatgggat ttatctgttt cacagcctac caacagacca atatggcaat
     7321 gagattccag aggaggcaga gagactggga cagccagcct cacatggctg tgtccgcatg
     7381 agcagagcag acgccaaatg gttttatgac aatatcccag aaggcatcag cgtcacaata
     7441 gaatagccct aatctccctc agaatagcct gagcagatag aggaagagcc tgttaatatt
     7501 agcaggcttt taaagctcct taaaaggctg caaaaaggaa cgaaaaaaga cctgaaacag
     7561 gtccattgat ctaagagaag acaagtaact agccttctag caaagtgttt taaaaatgcg
     7621 ttagtttagt agcttcgtga taatacaatt aataatattt atttaaaaaa actgtaaatt
     7681 tcgaccactg ttcctggatt ttttcattta aacgtttatg ccatgactta tgagcattct
     7741 ctctaatttc ttttaggtat atattttcta ctaccctttt ttgactatgt tctcgctctt
     7801 tttttatttg ctgtcttaaa ttctcttgtt ttttctgttc ttctaactct ttttgagctt
     7861 tcttctgttc ttgctctatt atgtcttgag gtttagattc tcctacaatc catatttctg
     7921 aacctaagac aaaaccatct gaggtaatat gaactctaaa tttatcacca ttagaagcaa
     7981 ttttattata tggaacatat gtttcttctt tggaatttgt tttttgtgtt ctcgctgatt
     8041 ctaaagagaa cacaattttt ccatcccact ttgcaattgg atagtaccgg ttatttgtta
     8101 agtcaccatt gctttttttt tggacttgta ctaattcagt ttccttatca tcttcttcga
     8161 ctttaaatat tctaatcaaa gatcctggac tagtttttac tactatttct ttgtcattat
     8221 ttttgattgg tttaacgcca aagtctcgag cgttttccca atctcttcta aatcctatta
     8281 ccttttggtc accaatttgt ggtgcttctg tataatcatc ataaccataa tagccttgcc
     8341 ctaaaactgg agaattttca taatcactat ttgcacttac ttcgttgaaa catattaaac
     8401 ttagtaaagg taaattaacg attaaactca tcactaactt cttcttcatt ttttcttcct
     8461 aacctccatt acttatgttt atttaataat agctagggtt agtataaatg agatgttgtg
     8521 taaggtaaag atgtttatta aaagtgacta aaagtaaaga aataatccta atagtagttt
     8581 ggggatattt tgatttatac aaaaaataat gtcattgaac acgctttatc taaaatagtc
     8641 taacattcta acgaaaataa ttccaattat tttcatatac tggctagaca tgctgtatta
     8701 gcttaatcaa gaattacagc cgcagtttta aagacactca ggttagtgta ttataaaaag
     8761 ctggtgtggg ttacaaagga tttcatatca cttagattat gtcataatta gttaagatga
     8821 tgaatcctta tctaaaaaca aagcaaactt gtacgtttgc gactttcgtg atctttaagc
     8881 ttacaaaagc tgagtaaatt ggtataatga tcattaaaag agctcatgct atgatgtaga
     8941 cctataaaag gagaaaacca tgacatttga agagattttg ccaggcttga aggccaagaa
     9001 aaaatacgtt cgtaagggct ggggaggcgc tgaaaactat gttcagctgt ttgatagcat
     9061 tgaacaaaat ggtgtggcac ttgaggtgac gccttacttt ttgattaacg tgtcaggagc
     9121 tggcgagggc ttttccatgt gggcaccgac tccctgcgac gttcttgcta ctgactgggt
     9181 agaggtctat gactaagcgg gtgctgatca ctggtgtgtc atcgggcata ggactggcac
     9241 aggcgcgcct gtttttgaga aatggcttta ctgtttatgg ggttgacaag gcaaaaaagc
     9301 ctgatttatc aggagatttt cagtttttac agttagatat tacaggtgat ttagctgagc
     9361 tttttgaggc tgtgcctagg gttgatgtgt tgtgtcatac tgcgggcgtt cttgatgcct
     9421 ataagccctt gcttgatacc acacaggctg attttgaggc tctctttcag gtcaatttct
     9481 ttgcagctgt ccgcatcacg cgtcactatt tggcacagat gctgacagct caatcaggta
     9541 ttatcatcaa tatgtgctct attgctagct tcatggcagg tggcggcgga gctgcctata
     9601 cctccagcaa gcatgctctg gctggtttta ccagacagct agcgcttgat tatgccaagg
     9661 caggcattca ggtttttggc attgcccctg gcgcagtgca aacagcaatg acagccacag
     9721 actttgagcc aggtggctta gcccagtggg tggctgatga gactcctatc ggtcgttggc
     9781 ttagggctga agaaatagcc gagctgacca tgtttttggc atctggaaaa gctagcgcca
     9841 tgcagggaga aattgttaaa attgatggcg gttggagctt aaagtgaaac agcacatcga
     9901 cataaggcct agcaagatct ggcttgtctg tacagagggt gacagttgat agctgtatca
     9961 agcaatcttg tcacaggcta agagggagct gatgaagttt tttccatgaa gcctagtgcc
    10021 tagtaggttt gcttaataca gcaggagcct acctgtctag aggattcgat caatagaggt
    10081 gataacatga ctgcagaaga attatggtct caataccagc aaatcaatcc tggtgttggt
    10141 gatctagctg aggcctgggc ctttggagct gagcctgatt tattagcgca attagtgcta
    10201 gaaggcacta aaacagctac agcctctgcc tatgactgat atgagcctga tcatgagccg
    10261 ctttccaaag agggcagcta tgacgtgatt ttggatagta gggatcaggc gatctgtatt
    10321 atccagatta ctaaggttag tcttgttccc ttcaaggacg tgccagcaga gcatgcctat
    10381 aaggaaggag agggtgataa aagcttggaa gaatggcggc tgcttcatga ggcctttttc
    10441 agaccttatt ttgaagaggt aggcttacgc tttaccgagg atagccttat tgtgttagag
    10501 gagtttcaga gggtttaccc tgaagctgct aaaaaggaga aataaatgaa attagccctt
    10561 gttggtacag gcatgattgt caaagaggtt ttgcctgttt taaaggagat caaaagcata
    10621 gacttaatgg cgattgtttc aacgcctcgt agtcttgaaa ccgcagaggc gcttgctgac
    10681 gcctttggca ttcaacaggc cagctgtcag ctagccgagg tcctaaaaaa tgaagaggtg
    10741 gatacggttt atgttgccac cccaaatcat ttgcattttg aagtggctaa gcaagccctt
    10801 gaggctggta agcatgtcat ttgtgaaaag ccatttacca tgacagccaa ggagcttgat
    10861 gctttaagca gcattgcaag agctaagcag ctgatattat tagaagctat taccaaccaa
    10921 tatttgccaa acacccaatt tattaaggat cacttgactg agttaggaga gattaagctt
    10981 gtggagtgca attattctca atattcctct cgttatgatg cctttaagcg tggggagatt
    11041 gcaccagcct ttgatcctaa aaagggtgga ggggccttgc gtgatttgaa tatttataat
    11101 atccatctgc tcgttggctt atttggcaag ccccaaacgg ttcagtacct agctaatatg
    11161 gagcggcagg ttgacacctc tggtgttttg ctgatggatt atgagcgatt taaggctgtt
    11221 tgtattgggg ctaaggattg cagtgcagag attgtctcta cgattcaggg gaataaaggc
    11281 tttctttctg ttttaggtgc tcctaatgct gtaccagagc ttttactagc cattcgaggt
    11341 gagcaagcaa ggaccgtcaa ctttaaccac ccgtctcatc gcatgtacga tgaatttatt
    11401 gccttttcag atattatctc taataaggac atggaaaggg cagagcaggc cttggagcac
    11461 agcaaggcag tcatggctgt tttagagcag gcagcagctt cgctagaaag cgatagctaa
    11521 gagtagctag tggctacaag ctaagtcatc ttttttgcta gctgtcttaa gaagtgatga
    11581 cccttcttgt tctatcagat acaggtcttg ttcctgatga ctcggagtct ttcaatcgcg
    11641 gagcctaact gcttttttca tagtgagggg tctaatttgc agcttgcttt gtttacgaca
    11701 tctttgatac ttagcgatga caggcagctc tagctagctg ctttaaaaaa ggagtcaagg
    11761 taggtaaggg agtttgtctg aagctaagga ctattgcagc attcttgttt tttctgcaaa
    11821 ttaaggccat ttgtgctata atgagatgat ctatgtacaa acggaggaag tcattatgcc
    11881 aaactacgcc attatcctag cagctggaaa gggaacccgc atgaaatcag ggcttcccaa
    11941 ggtgctgcac aaggtatcag gcttaagcat gctggagcat gtcctcaata gcgtctcagc
    12001 cctagctcct caaaagcaac tcacagtgat cggtcatcag gcagagcagg tacgtgccgt
    12061 cctaggtgat caatcactga cagtggtgca agaggagcag ctaggaacag gccatgcagt
    12121 catgatggca gaagaggagc tatctggctt agagggacaa accctagtga ttgcaggtga
    12181 cacccccttg atcagaggag aaagtctcaa ggctctgcta gactatcata tcagagaaaa
    12241 gaatgtggca accattctca cagccaatgc caaggatccc tttggctatg gacgaatcat
    12301 tcgcaatgta gcaggagagg tggtcaatat cgttgagcaa aaggacgcta atgaggcaga
    12361 gcaagaggtc aaggagatca acacagggac ttatatcttt gacaataagc gcctctttga
    12421 ggctctaaag catctcacga ctgataatgc ccaaggggag tactacctaa ccgatgtgat
    12481 cagtattttc aaggctggcc aagaaagggt tggcgcttac ctgctgaagg attttgatga
    12541 gagcctaggg gttaatgatc gcctagccct agc
//
LOCUS       DARYXS010000057        12341 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.058, whole genome shotgun sequence.
ACCESSION   DARYXS010000057 DARYXS010000000
VERSION     DARYXS010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12341
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.058"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            180..2063
                     /locus_tag="TV193_001329"
     CDS             180..2063
                     /locus_tag="TV193_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1513520.1"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVAIGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYLVTLLVGLGLAFVIA
                     YIWGFKDKSDQEAPATQVKSEPAQKASAAEELLSPVAGELIDLSSVADPVFSSGSMGQ
                     GVAIKPEGRILCSPVDGRVEAALETGHAYVIKSDKGAEILLHIGIDTVSMAGEGFETF
                     VKVGQMVKAGDALGSFDIARIQQAGLDTTTMLLVTNSADVHAVQILAQGKVTVGSPVI
                     LVK"
     gene            2292..5348
                     /locus_tag="TV193_001330"
     CDS             2292..5348
                     /locus_tag="TV193_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL1513521.1"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLIRVKAEDKVVQTS
                     PSVSAIDDLHYLSENSKKEFKEGLSKAGEVPEKLKDILSKAQQADKQAKVLAEMKVPE
                     KIAMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSFF
                     WQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDTQKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDIERDSIPKVNGKESNENIQRSIAVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAQYIDLLLVQVYGTQGEKGDWDPVARKPEKTMEEHWESYSK
                     YIRPEQYMVGFSFYEENAGSGNLWYDINERKDDHNPLNSEIAGTRAERYAKWQPKTGG
                     VKGGIFSYAIDRDGVAHQPKKVSDDEKRTNKAIKDITDGIVKSDYKVSKALKKVMEND
                     KSYELIDQKDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPDIKSLEGLNKLKKLA
                     KLELIGLSQITKLDSLVLPANAKPTKDTLANVLEAYDSAKKEETKAIPQVALTISGLT
                     GLKELNLAGFDRDSLAGIDAASLTSLEKVDLSSNKLDLAAGTENRQILDTMLATVTKH
                     GGVSEKTFVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSE
                     ADYKAYQEQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETY
                     KVEFFSPTNSTKPVHEAKVVVGAEKTMMVNLAEGATVIGGDADPTNAKKVFDGLLNND
                     TTILSTSNKASIIFELKEPGLVKYWRFFNDSKISKADCIKEAKLEAFVGHLEAGSKVK
                     DSLEKSSKWVTVSDYSGEDQEFSQPLNNIGAKYWRITVDTKGGLYNWPSLPELQIIGY
                     QLPAADLVMAMLATAEELSQQKDKFSQEQLKELEVKIAALKAALDSKMFNADAINAST
                     ADLKAYVDKLLADRTDQEKVAKAAKVEQPVATDIKENTEPENPKTD"
     gene            5705..6589
                     /locus_tag="TV193_001331"
     CDS             5705..6589
                     /locus_tag="TV193_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1513522.1"
                     /translation="MKTLLGSIEAGGTKFVCAVGDRDFAVVDKVQFPTTSPKETIERT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLTAAFAIP
                     FYVTTDVNSSAYGEAISRPDVDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYVM
                     QHLDDVANAFLGVCPFHRGCLEGMAAGPSLEARAGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLVRVQEAFTRLINGYLPVADVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            6705..7649
                     /gene="manA"
                     /locus_tag="TV193_001332"
     CDS             6705..7649
                     /gene="manA"
                     /locus_tag="TV193_001332"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEL1513523.1"
                     /translation="MSEPLFLTSCMHDKIWGGTKLREVFGYELPTETTGEYWAISAHP
                     NGVSTVSSGSYQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAY
                     GLAHEGELGKTECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTI
                     GKPENSTPATLELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSL
                     TIDQAVYELQKGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            8025..10553
                     /gene="secA"
                     /locus_tag="TV193_001333"
     CDS             8025..10553
                     /gene="secA"
                     /locus_tag="TV193_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEL1513524.1"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGVVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERAIQYATTTAA
                     QNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            10669..11025
                     /locus_tag="TV193_001334"
     CDS             10669..11025
                     /locus_tag="TV193_001334"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEL1513525.1"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHH
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            11022..12122
                     /locus_tag="TV193_001335"
     CDS             11022..12122
                     /locus_tag="TV193_001335"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1513526.1"
                     /translation="MISSLHRPTVARVDLEAIRANIDHIHQHIPKKVRTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADDSDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIR
                     LGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVG
                     TLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
BASE COUNT         3475 a         2294 c         3111 g         3461 t
ORIGIN      
        1 aaacgcttga cataaaaaat attcgtgtta aaatgatagc aagaagtgaa gcggattcac
       61 aatagtaaat tgaaagacca tcttgagtcg gacagtaggg taggtccgcc aatattggat
      121 aggctcaaga aaagctattt cgatagacta taacagacaa aaaaggagat gctatcggta
      181 tggataatca tcagattgca aaagaggtta tcgaggcctt aggcggtcgt gaaaatgtca
      241 gaagtgtggc tcattgtgcg acgcggctgc gggttatggt tcatgacgag ggtaagatca
      301 ataaggaaaa agcagaggct attgataagg ttaagggtgc ttttttcaac tcaggccaat
      361 atcagctgat ttttgggaca ggtacggtta atagcattta tgatgaggtt gtagctctag
      421 ggcttccagc tgctttggca ggtgagcaaa aggagcaagt ggtcaagtct ggaaatgcct
      481 ttcagcgggc tattcgtacc tttggtgatg tctttgttcc gatcattcct gctattgtgg
      541 cgatagggct gtttatgggt gtacggggtc tcttgacgca gccggctgtt atggagttct
      601 ttggtattca tgactatggc gacaatttcc tcatgtacac tcggatttta acagatacgg
      661 cctttgtcta cctgccggcc ttggttgctt ggtcagcctt tagggtattt ggtggcaacc
      721 ctatcattgg gattgtcctt ggcttgatgc tcgtctctaa tgagttgcca aatgcttggg
      781 tggtagcctc aggaggtgat gttaagccct taactttctt tggttttgtt ccagttgttg
      841 gttatcaagg tacggtattg ccagccttct ttgttggtct ggttggtgcc aagctggaaa
      901 agtggctgca taagcgggtg cctgatgcgc ttgatttgtt ggcaacgccg tttttgacct
      961 ttgctattat gagtgccttg gggctctttg tgattgggcc tatctttcac tccttggaaa
     1021 accttgttct tgcagggaca caagcagttt taggtctgcc ttttgggatt gccggccttg
     1081 ttattggggg tgttcagcag ctgattgttg tgacaggtat ccatcatatt ttcaatttct
     1141 tggaggcgca gctagttgcc aatacaggaa aggatccctt taacgcttat ttgacagctg
     1201 ctacggccgc ccaagcagga gcaactctag cggttgctgt taaaaccaag tctgcaaaat
     1261 taaagggttt agcctttcca tcagctctgt cagctctttt agggattact gagccggcta
     1321 tctttggggt taatctccgc tacccaaagg tatttgtctc aggacttatc gggggcgcag
     1381 ctggtggctg ggttgcaggg attcttggca ttgctggtac cggctttggg attacggttt
     1441 tgcctggtgc actgctgtat cttaatggtc agctactaca gtaccttgtg acactgttgg
     1501 ttgggcttgg tctagctttt gtgattgcct atatttgggg attcaaggac aagagtgacc
     1561 aagaagcacc ggctacccaa gtaaaatcag agcctgcgca aaaagcctct gctgctgagg
     1621 agctgcttag tccagttgca ggggagttga ttgatttgtc atcggttgct gatcctgtct
     1681 tttcgtcagg aagcatgggc caaggcgttg ccatcaagcc tgaagggcgc attctctgct
     1741 caccggtaga tggcagggta gaggctgccc ttgagacagg tcatgcttac gtcatcaaat
     1801 cagataaggg agcagaaatc ctactgcata ttggtattga taccgtttca atggcaggtg
     1861 agggctttga aacctttgtt aaggttggtc agatggtcaa ggctggtgat gctcttggaa
     1921 gctttgatat tgcaaggatt cagcaggcgg gccttgatac tacaaccatg ctgcttgtca
     1981 ccaatagcgc agatgttcat gctgttcaga ttttggcaca aggtaaggtg actgttggca
     2041 gtccagtgat ccttgtaaaa taatttgaaa agagttgatg atttcatctc tttttacatg
     2101 taagattaaa atattcacca taaaattaca gaaattaaaa gaccttaagt ttcttttatt
     2161 ttacctatac tttgtgcatt gcttttgatc atgaggtcta ctatacttta gacgaacgca
     2221 gagaatgcgc ttacattttt ggttcagcaa agatttgcca ttctttggta tcaaaataaa
     2281 ggagtgtccc aatggaaaaa caggtgttag tcaagaaaac actgaaatgt gtttgtgctg
     2341 cagcgttaat ggtggctata ttagctgccc aacatgattc actcataagg gtcaaggcag
     2401 aggataaggt tgtgcaaact agtccatcag tctctgctat tgatgaccta cattacctgt
     2461 cggaaaacag taaaaaagaa tttaaggagg ggttatcaaa ggcaggagaa gtacctgaaa
     2521 agctaaagga tattttatcc aaggcacagc aggcagataa gcaggcaaag gttcttgcag
     2581 aaatgaaggt tcctgaaaaa atagccatga agcctttaaa ggggcctctt tatggtggct
     2641 attttaggac ttggcatgat aaaacatcag atccggctga aaaggataag gttaattcta
     2701 tgggagaatt gcctaaggag gttgacttag cctttgtttt ccatgattgg accaaggatt
     2761 atagcttttt ctggcaagaa ttggcgacca agcatgtgcc aacgctgaac aagcagggaa
     2821 cacgtgtgat tcgtaccatt ccatggcggt tccttgcagg cggtgatcat agtggtattg
     2881 ctgaagatac gcaaaaatac ccaaatactc cagagggaaa taaggccttg gcaaaggcta
     2941 ttgtagatga atacgtttat aaatataatc ttgatggttt agatgttgat attgagcggg
     3001 atagcattcc aaaagtaaat ggaaaagaga gtaacgaaaa tattcagcgc tctattgctg
     3061 tttttgaaga aattggcaag cttattgggc caaagggcgc tgacaagtca cgtttgttca
     3121 ttatggatag cacctacatg gctgacaaga acccattgat tgagcgcggt gcccaatata
     3181 ttgatttgct gcttgtgcag gtttatggca ctcaaggtga gaagggagat tgggatccag
     3241 tcgctagaaa acctgaaaag acaatggagg aacattggga atcgtatagc aaatacattc
     3301 gtcctgagca gtacatggtt ggtttttctt tctatgagga aaatgcgggc agtggtaacc
     3361 tctggtatga tattaatgag aggaaagatg atcataatcc gttaaattca gagatagctg
     3421 gtactcgtgc tgagcgttat gcaaaatggc agcctaagac aggtggtgtc aagggaggga
     3481 ttttctctta tgcgattgat cgcgatggtg tagcgcatca acctaaaaaa gtctcagatg
     3541 atgagaaaag aactaacaag gctataaagg atataacaga tggtattgtc aaatcagatt
     3601 ataaggtttc taaggccttg aagaaggtta tggaaaatga caaatcctat gagctgattg
     3661 atcagaaaga ttttccagac aaggctttgc gagaagcagt tattgcacag gttggaagca
     3721 gaagagggga tttagagcgg ttcaatggaa ccctgcgctt agacaatccg gatatcaaga
     3781 gtttagaagg cctgaataag cttaaaaaac tagctaagct agagctaatc ggtctatcac
     3841 aaatcacaaa gctggatagc ttagtcctac ctgcaaatgc taagccgacc aaggatacgc
     3901 tggccaatgt tcttgaagcc tacgacagcg ctaagaagga agagactaag gcgattccac
     3961 aggtggctct gaccatttct ggtctaactg gcttgaagga attaaatctt gctggctttg
     4021 atcgtgatag cttggctgga attgacgcag ctagcctaac ctctcttgaa aaggtggatc
     4081 tctctagtaa taagctggac ttagcagctg gtacggaaaa tcgtcagatt cttgatacca
     4141 tgctggcaac agtgactaag catggcggtg ttagcgaaaa gacgtttgta tttgatcatc
     4201 aaaagcctac tggtctttat cctgatactt atggcactaa gagccttcag ttaccagtag
     4261 caaatgatac aattgatttg caggctaagc ttttatttgg aacagttacc aatcagggca
     4321 cgctaatcaa tagcgaagct gactataagg cttatcagga gcaggaaata gcaggtcacc
     4381 gttttgttga ttcaagctat gattacaaag cctttgcagt gacctacaag gactataaga
     4441 tcaaggtgac tgactcaacc ttaggtgtca ctgatcacaa ggacttatcc actagcaagg
     4501 aggagaccta caaggttgaa ttctttagcc ctactaatag cactaagcct gtgcatgagg
     4561 ctaaggttgt cgttggtgcg gaaaaaacca tgatggttaa cctagcagag ggagcaactg
     4621 tgattggtgg tgatgcagat ccaacaaatg caaaaaaagt gtttgatggt ttgctcaata
     4681 atgatacaac aattctgtca actagcaata aagcttctat catttttgaa cttaaagagc
     4741 ctggcttagt caagtattgg cgtttcttta atgacagcaa aattagtaaa gctgactgta
     4801 ttaaggaggc caagcttgaa gcctttgttg gccatcttga agctggctca aaggtaaagg
     4861 atagcttgga aaaatcatca aaatgggtaa cagtttcaga ttattcagga gaggaccaag
     4921 agtttagcca gccgttaaac aacattggtg ccaaatattg gagaataaca gttgatacta
     4981 agggaggact ttacaattgg ccatcacttc ctgagcttca aatcattggt tatcaattac
     5041 cggctgcgga tcttgtgatg gcaatgctag ctactgcaga ggagctatct cagcaaaaag
     5101 acaagttctc tcaagagcag cttaaggagc tcgaagtcaa aatagctgcc ttaaaggctg
     5161 ctttagatag taagatgttt aatgccgatg ctattaacgc tagtactgct gatctgaagg
     5221 cttatgttga taagctttta gctgatagaa ctgatcagga aaaagtagct aaagcagcta
     5281 aagttgagca gcctgtggct actgacataa aagaaaatac tgagccagaa aatccaaaga
     5341 cagactagct tatccttgag caggctgtcg ttcttggccg ttagcttgag gttactgatc
     5401 attacgctaa cacattaagc tttagagata aggcgatgaa cacaccatta aaagcaattg
     5461 tttgtgctgc ttcttggtgg cagctcctgc tgccaaggtt tccctcctaa aatcaattgc
     5521 cttatctctt aaaggcatat caaaaatctg agatagtcct atcccagatt tttggtcttt
     5581 tctaggaggc aaggaagcaa gcgatgatgt ttagctacta aggtagctgc tgattagctg
     5641 gtgggatttt gagccttgtg agaataacca gcacagggct tatcactatt attaaggaga
     5701 aaagatgaaa acattacttg gaagtattga agcaggcggg acaaagtttg tctgtgctgt
     5761 tggtgatagg gattttgctg ttgtggataa ggtgcaattt ccaacgacaa gtccaaaaga
     5821 gactattgag cgtacgattg cttattttaa gcaatttgag gccgacttgg ctagtattgc
     5881 tattggctcc tttggaccga ttgatattga tcctaagtca gctacctatg gctacattac
     5941 cacaacaccc aagccaggtt gggcaaatgt agatctatta gggcagctga cagcagcctt
     6001 tgcgattcct ttttatgtga cgactgatgt taatagttct gcctatgggg aggctatctc
     6061 tcgacctgat gttgacagtc ttgtttatta tacgattgga acaggtattg gtgctggagc
     6121 tattcaaaaa ggtgagttta tcggtgggtt aggtcataca gaggcgggac atacctatgt
     6181 tatgcagcac cttgacgatg tggcgaatgc atttttgggt gtttgtccat ttcatcgggg
     6241 gtgcttagag ggcatggcag cagggccaag ccttgaagca agggcaggga ttaaggggga
     6301 gcttcttgat cagaaggccg ctgtttggga tattcaagcc ttctatatag ctcaggctgc
     6361 tgtacaggca acgctgcttt atcgtcctca ggttattgtg tttggtggag gtgtgatggc
     6421 acaggagcac atgctggtgc gtgttcagga ggcctttacc agactgatta atggttattt
     6481 accagtagct gatgttagag aatatttggt cacaccagca gttgcaggta atggctcggc
     6541 cactcttggg aattttgctt tagcaaagct gattgctgaa aagagctaga tacttgagcc
     6601 tatttgataa aagtcctaga gtcatttgca aaatgtgcct gaaattggta gaattggggc
     6661 aaagaatgtc accataggtt agtgaaaaga gaatgaggat tactatgtca gaaccattat
     6721 ttttaacatc atgcatgcat gataagatct ggggcggaac aaagctaaga gaggtgtttg
     6781 ggtatgagct tccaaccgaa accactgggg agtattgggc aatctcagct caccctaatg
     6841 gtgtttccac agttagcagt ggtagctacc aaggccaaag gctagatcag ctttatgcag
     6901 aaagaccaga gctatttgga aatccaaagg aaaaggtctt tccgctgttg acgaagattt
     6961 tagatgctaa tgactggcta agcgttcagg tacacccaga tgatgcttat gggctggccc
     7021 atgagggaga gctaggaaag acggaatgct ggtatattat ttcagctgaa gaaggcgctg
     7081 agattgttta tggtcatcat gcaagctcta aacaagagct tcgtgcgatg attgaggcgg
     7141 ggaactggga agagttgttg acgcgagttc cggttaaggc tggtgatttc ttctatgttc
     7201 caagcggcac gatgcatgcc attggtaagg gaattttgat cttagagacg cagcaatcct
     7261 cagacacgac ctatcgcgtt tatgattttg atcgtcgaga cgctgaaggt cagcttcgtg
     7321 agctccatat tgagaaatct atcgatgtcc taactattgg caagcctgag aacagcacgc
     7381 cagccacact agaacttgag cacttggtct ctacctgctt agtatctaat cccttcttta
     7441 cagtttacaa atgggagatt gatcaagcag tcagcatgaa gcaatcagcc ccttacctgc
     7501 ttgtcagtgt gctagctggt cagggaagcc ttacgattga tcaagctgtt tacgagcttc
     7561 aaaagggtat gcattttatc ctgccaaatg atgtgacgtc atggagcttt gatggtcagc
     7621 tggaaatgat tgtcagtcat cctaattaag tacagaatac acgaaaacac caagaaagac
     7681 tgtttggaca agcggccttt ctttttctga tatcttatca cgacagacgc atgaagaaaa
     7741 aatttccaag atatttctga atgcgaaaac ttattctgaa aaataggaaa gccatagcga
     7801 tagttgcaga aaagaaattt ttcaagaaaa gtttatagag ggagaatata acaattcagg
     7861 aaacactctg tcaaataccc taaaatggct attttgctat tttcacaact ttttcaataa
     7921 atgattttct tcatgcgtct gtcatggata tcttatgatc atttcttgaa ctgcctgcct
     7981 atttatgtta gaataaaatg attagtcgat cgaaaggaaa gagaatgagc aatattctac
     8041 gcaaagtcat tgaaaatgat aaaggcgaat tacgaaaatt agaaaaaatt gcgaaaaaag
     8101 tagagtccta tgctgactat atggagtcct tgtcagataa agacctacaa gcaaaaacgc
     8161 ccgaatttaa acaacgttat caaaatgggg aaacccttga gcagttatta ccagaagcat
     8221 ttgcggttgt ccgcgaggcg gctagacgtg tgctgggact ttacccttat cgtgttcaga
     8281 tcatgggggg ggttgtcttg cacaatggag atgtccctga gatgcgtacc ggtgaaggta
     8341 agacccttac agcgaccatg cctgtttacc ttaatgccct tgctggcgaa ggggtacacg
     8401 ttatcactgt taatgaatac ttgtcaactc gtgacgcgac agagatggga gaggtgtata
     8461 gctggctagg gctttcagtc ggtatcaacc tagcagccaa atcaccagct gaaaagcgtg
     8521 aggcttatct atgtgatatt acctactcaa ccaactctga ggtaggcttt gactacctgc
     8581 gtgataatat ggtggttcgt caagaggaca tggttcagcg accactgaac tttgccttgg
     8641 tcgatgaggt tgactctgtt ttgattgacg aggcaagaac acctctgatt gtatctggtg
     8701 ctgtgagctc agaaacgaat cagctctata ttcgtgcaga catgtttgtc aagaccttgg
     8761 attcagtgga ttacatcatt gatgttccga ccaagacgat tggcctaagc gactcaggta
     8821 ttgataaggc agaaagctat ttcaacctca gcaacctata cgatattgaa aatgttgcct
     8881 tgacccactt cgtggataat gcccttcgtg ctaattatat catgcttttg gatattgatt
     8941 atgtggttag cgaggaaggc gagattttga ttgtagacca gtttacaggt cgtacaatgg
     9001 agggacgacg cttttcggat ggcttacacc aagctattga ggcaaaagag ggcgttcgta
     9061 ttcaagagga atcaaaaaca agtgcctcta ttacctacca aaacatgttc cgtatgtata
     9121 agaaattggc gggtatgact ggtacagcaa aaacggagga agaggaattc cgcgaagttt
     9181 acaacatgcg tattattccg attccaacca accgtcctat tgctcgtatt gatcacacag
     9241 accttcttta tgcaacgttg aattcaaaat tcaaggcagt ggttgcagat gttaaggctc
     9301 gctatgaaaa ggggcagccc gttctagttg gtacagttgc tgttgagacc agtgacctga
     9361 tttctaaaaa gctagtagaa gcaggcattc cgcatgaggt cttaaatgct aagaaccact
     9421 ttaaagaagc acagattatt atgaatgctg gtcagcgtgg tgcggtaacg attgcgacca
     9481 atatggctgg tcgtgggaca gacattaagc tcggtgaggg tgtccgagag ctcggtgggc
     9541 tttgtgttat cgggacagag cgtcatgaga gccgccgtat tgataatcag cttcgtgggc
     9601 gttcaggtcg tcagggagat ccaggggagt cacaattcta cctctcctta gaggacgagc
     9661 tgatgaggcg ctttggtaca gaccgtatta aggctttctt ggatcgtatg aacaatgatg
     9721 acgaggatat tgttatcaag tccagaatgc tgtcacgcca ggtggagtca gctcaaaaac
     9781 gtgttgaggg taataactat gacacacgta agcaggtctt gcagtatgat gatgtgatgc
     9841 gtgagcagcg tgagattatt tacgctaacc gtcgtgatgt tatcacagca aatcgtgacc
     9901 taggtcctga aattaaggca atgatcaagc gtacgattga tcgagcagtt gatgcccact
     9961 cacgtaccaa tcgtaaggac gctattgacg ccatcgtgac ttttgcgaga acatcaattg
    10021 tcccagagga aaccatcggt gctaaggaat tgcgtggcct caaggacgat cagatcaaag
    10081 acaagctcta tcagcgtgcc cttgagattt acgataagca gttatcaaaa ttgcgcgatc
    10141 aggacgctat cttagaattc cagaaggtgc tgattttgat gattgttgac aacaaatgga
    10201 cagagcatat tgatgcctta gaccagcttc gtaatgcggt tggtttgcgt ggttatgcgc
    10261 aaaataatcc agttgttgaa tatcaaagtg aaggcttcaa gatgtttcag gatatgattg
    10321 gtgctatcga atttgatgtt acacgtacca tgatgaaggc acagattcat gagcaggagc
    10381 gcgagcgtgc aattcagtat gcaacaacaa ctgcagcaca aaacattcag tcgcaggcta
    10441 tcggtgctga ttttgattca tcagctgatt tttcaagagt cgagcgcaat gatgcttgtc
    10501 cttgtcactc tggtaagaag tttaaaaact gtcatggtcg taaggctttt taaggatagc
    10561 gtgatggcca tgttgaaaac ctgtgaggag ctgagatttg ttctcggctt ctccttgttt
    10621 aggatttgtt tccctaaatt aaagtgaagg ctggtaaaat aaaggcaaat gattgttgga
    10681 catgggatag atttacagga tatttcagct attgaaaagg tttatttgag aaatgctaga
    10741 tttgctagaa aggttttgac ggacaaggag ctagcgctgt ttgagcaatt ttcccatcac
    10801 cgaaaaatga cctatctggc cggccgctgg gctggtaagg aggccttttc aaaggcaatg
    10861 gggacaggga ttggccagct aacctttcag gatattgaaa ttatcaatga cagcaaaggg
    10921 cgtcccgtca ttacaaaatc tccctttcag ggtaaggcct ttatcagtat ttcacatagt
    10981 gggggctatg ttcaagcaag tgttattttg gaggatttag catgatttca agcttacatc
    11041 gaccaacagt agctagagtt gacttagaag ctattcgagc aaatattgac catattcatc
    11101 agcatattcc taaaaaggta aggacatatg ctgttgtcaa ggccaatgct tatggtcatg
    11161 gggcagttgc agtgtccaag gcagttgagg atcaggttga tggctattgc gtatcaaacc
    11221 ttgatgaagc cttggaatta cgtcaggcag gcattgataa ggaaatcctt attttagggg
    11281 tgattttagc aagtgaattg cagctagcca ttaagcatca gctgacgata acagtggcca
    11341 gcttagagtg gctagagctt gccaaaaagg aatcggttga tttcagtcag cttcatgtgc
    11401 atgtcaaggt tgactcggga atggggcgca ttggtgtcag gtcgcttgct gaggccaatc
    11461 agctcatctc aatcttatcc gatatgggag tgcagcttga cgggattttc acgcattttg
    11521 caaccgcaga tgactctgac catgccatgt tcgataagca gctgaccttt ttcaagcagt
    11581 tggtggagca gctagataag aggcctgcat tagtgcatgc aagcaactct gcaacaagcc
    11641 tttggcatag tgaaacaatt tttaatgcca ttcgccttgg tattgttatc tatggactca
    11701 atccaagcgg caatagcttg agtctacctt gtcccttaaa ggaagccttg tccttagaat
    11761 cacgtttggt tcatgtgaag caaattcagg caggggatag cgttggctat ggagctagct
    11821 atgtagcagc agaaccagag tatgtcggga ccttacctat cggctatgct gacggttgga
    11881 ctcgaaatat gcagggcttt aaggtattgg tagaagggga attttgtgac attattggtc
    11941 gtgtgtcgat ggaccaattg accattcgtt tgcctaaagc ctatcctatc ggcactaagg
    12001 tgaccttgat tggacagcag ggtaaacaag taatcacagc aaccgatgtt gccgattata
    12061 gaggtacgat taattatgag gtgctttgct tgctgagtga tcgtattcct agagaatatt
    12121 aggaaattga gcctaggctc aactattgac tggcctcaag gctgtctttc aaatgattag
    12181 tcctgtaaag gtcttgagac ctcaggctaa cagcatagat agagcagatc aagacaggtc
    12241 ttgtttttct gcgggttaag aaaaagaata agaaaaggcc cttaccttta tccgagtatt
    12301 aaggcattaa tacaaaaaat cttgcatttt attttgcttc a
//
LOCUS       DARYXS010000058        12206 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.059, whole genome shotgun sequence.
ACCESSION   DARYXS010000058 DARYXS010000000
VERSION     DARYXS010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12206
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.059"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(177..986)
                     /locus_tag="TV193_001336"
     CDS             complement(177..986)
                     /locus_tag="TV193_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1513527.1"
                     /translation="MDKLILGRYIPGNSIIHRLDPRSKLLAMIIYIIIIFWANNVVTN
                     LLLLAFILLLIFLSQIKWSFFFNGVKPMIGIILFTTLFQVFFTQGGSVLFQLGIIKIT
                     SLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVEALLKPLVRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQKARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGDSRTKYRLLSWQLKDTLAIILVVILGIFLFCLKSPSRLT"
     gene            complement(979..1821)
                     /locus_tag="TV193_001337"
     CDS             complement(979..1821)
                     /locus_tag="TV193_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1513528.1"
                     /translation="MSIHFQNVSYTYQAGTPFEGRALFDVNLDIVDGSYTAFIGHTGS
                     GKSTIMQLLNGLHLPTTGKVTVAGKEITSQSKNKDIKPIRKQVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSQKEAEALAREKLTLVGISEELFGKNPFELSGGQMRRVAIAGIL
                     AMQPDILVLDEPTAGLDPKGRKELMSLFKSLHQSGMTIVLVTHLMDDVANYADFVYVL
                     EAGKIILSGQPKAIFQHIDLLKEKQLGVPKVTAFAQRLAKQGFDLPYLPITLEELREV
                     LKHG"
     gene            complement(1797..2636)
                     /locus_tag="TV193_001338"
     CDS             complement(1797..2636)
                     /locus_tag="TV193_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1513529.1"
                     /translation="MSNIIEVKNLTFKYKQDQERYTLDDVTFHVKQGEWLSIIGHNGS
                     GKSTVVRLIDGLLKAEAGQIFVDGDLLTEDNVWDIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGVSHQEMIERVHQALQLVGMEAFKDKEPSRLSGGQKQRVAIAGAVAMRPM
                     IIILDEATSMLDPKGRLELIRTIQSIRQEYQLTVISITHDLDEVALSDRALVMNNGRV
                     ESVSTPQELFARGNQLINLGLDIPFTTSVVNMLKKDGYPIQGIYLTEKELEEQLCQFI
                     SKM"
     gene            complement(2639..3181)
                     /gene="pgsA"
                     /locus_tag="TV193_001339"
     CDS             complement(2639..3181)
                     /gene="pgsA"
                     /locus_tag="TV193_001339"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEL1513530.1"
                     /translation="MIKKENIPNLLTLARIVMIPLFLLITSFSKTVGWHTFAAIIFAV
                     ASLTDYLDGYLARKWQVVTNFGKFADPLADKMLVMSAFIMLVGLELVPAWVSAVIICR
                     ELAVTGLRLLLVETGDKVLAAAMPGKIKTVAQMLSIIFLLCHWTVLGTVLLYIALLFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            complement(3194..4198)
                     /locus_tag="TV193_001340"
     CDS             complement(3194..4198)
                     /locus_tag="TV193_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1513531.1"
                     /translation="MRETSLGELLRETRVGKNITLDEIEAKTGISSHYLLAMELDQFK
                     IIPEEKFGHFLKQYADIVGLDFDSLKRLYQLQVSFKKETGTPSVTQIVEEKLSKKRLQ
                     ENSYSEKIAQPEPSRTQPETLVIPVKTSLSSSKSAPTASHFKATDHRRTRETSASRLS
                     RYGNSAKTKKSAFPSALLGLIAVAIVGVIGFAVWKQFDKGQKAKEAEMSFLKSSQSSH
                     STASSSSEPKTVITTEGAENYLIANITKSKEAVDVTVSLTDAESSWISLTNSEIGEAG
                     MTLTKDNPTYSTTLPAETTESLLTLGVTKGVSVAIDGQPLDLSAMTSTDISYITLKIQ
                     "
     gene            complement(4248..5531)
                     /locus_tag="TV193_001341"
     CDS             complement(4248..5531)
                     /locus_tag="TV193_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1513532.1"
                     /translation="MTSLLKKDYPSIKETLHYGQLANGLRVYLIKKEGYSEKTAMLTA
                     RFGSLDTSFTVNCQRFDLPSGVAHFLEHKLFEDKDGNDIALTFTQLGSETNAFTTFDK
                     TSYFFSTVNEWQESLRLLQEFVAAPSFTEESVNREKHIITQEIEMYQDDPDYQAYSGI
                     LQNLFPNTSLAVDIAGTKESIRDITGSLLADSHAYFYHPSNMVLTIIGDIDIEEAFTA
                     IEAFQDSQPSQTQYDVQIAPLTYYPVIKSRSIDMDVATAKLAVGFRGQLMSSEYSLLT
                     YQVALRLLLAVLLGWTSKTYQDWYEKGKIDDSFDIEVDIQRDFQFVLISSDTSQPIAM
                     SNSIRKKISDFRCSRDVNEEHLELVKKEMYGDFMQSLDAIDQLASQFSLHLSEQETYF
                     DIPRIIETLALKDIIEIGSLFFEHAATSDFTVFPK"
     gene            complement(5533..6777)
                     /locus_tag="TV193_001342"
     CDS             complement(5533..6777)
                     /locus_tag="TV193_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1513533.1"
                     /translation="MKLIQGVQLHLIKNKTFKTNQITFRFSGDLNQKTVAKRVLVAQM
                     LATANDTYPTAKQFREKLAQMYGASLSTHVSTKGLVHIVDIDITFIQDQYAFYGEKLL
                     DEMIQFLKDILFSPLLSVAQYQPKLFDIEKRHLMTYVEADKEDSFYYSALKAKQLFYA
                     NDSLKLSKYGNTELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRMVQLLHQFPF
                     EGRRKKLDFFYLQQPVNVVNELVEQKQLNQSVLELAYHFPLVYGQAEYYALVVLNGLL
                     GAFTHSRFFTQIREKEGLAYSIGSRFDVYTGLFEAYAGIDRQHRTRALQLMVKELNDI
                     KMGRFSSSLVKKTKLMLKNNALLSEDNSKALIELEYMRSYIDPSYTLSSWLDEIDKVS
                     KLDIVRTANLLKLQAVYFLEGK"
     gene            6992..7405
                     /gene="yaaA"
                     /locus_tag="TV193_001343"
     CDS             6992..7405
                     /gene="yaaA"
                     /locus_tag="TV193_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEL1513534.1"
                     /translation="MTYTLFTDFITLQALLKEQGIIQSGGAIKGFLAQTEVFLNGQEE
                     QRRGKKLRVGDVITIPSQHIKIELVAPSQAEKTAYEAEKAEKERVAKMVKQMNQQAKK
                     AQTKQAATTKSKRGQATSAVKAKSNHQKPIRFPGL"
     gene            7407..8516
                     /gene="recF"
                     /locus_tag="TV193_001344"
     CDS             7407..8516
                     /gene="recF"
                     /locus_tag="TV193_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEL1513535.1"
                     /translation="MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIY
                     FLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQA
                     KLSDYIGAMMVVLFAPEDLQLVKGSPNLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQR
                     NAYLKSVHQLDNDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKL
                     SISYQASVSFEHQQEIYQQFMNQLKTTHQRDFLRKNTGVGPHRDDLVFYINDMNANFA
                     SQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNTRQTKLLGAVKKENVQT
                     FITTTSLEHLSQLPKDISLFKVNKGTIERDSIMID"
     gene            complement(8581..9444)
                     /locus_tag="TV193_001345"
     CDS             complement(8581..9444)
                     /locus_tag="TV193_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEL1513536.1"
                     /translation="MEGILFALVPMFAWGSIGFVSNKIGGKPSQQTFGMTIGALLFAL
                     VVWLVVRPEMSMKLWIFGILGGIIWSVGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPIQFVVGTIALLLLIVGFYFSSKQDETNAASNQLHDFSKGFRALTYS
                     TTGYVMYAVLFNNIMKFDVLSVILPMAVGMVLGAAMFMSFKVSFDQYVIKNSVVGLLW
                     GVGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVITGILCFI
                     VGAILLGIVKS"
     gene            complement(9615..12044)
                     /locus_tag="TV193_001346"
     CDS             complement(9615..12044)
                     /locus_tag="TV193_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEL1513537.1"
                     /translation="MMILTDEQRQRIAEEEYEKHTVGSPVLIDDDNSEFSIGYVSQIE
                     DSISGFQAYVVTDVKLPPHPTKADYAQVKHVTMLYRGSTGPDQWQKHPVDVVADWVGN
                     DLPMAMRILLPDQTPTKGTAQLRKAATFTNKTLKQYPNATFEFYGHSLGSMTVQYGVT
                     SVSDKNLSRISGVYIYNGPNTYRVLNEYQRKRAKLLHDRIYNYVDPHDIIGMGFDQKE
                     GAVGQVFVVNTKKVNDIVLQHMWHGYQYDQYGNMTDVNGRFVHANVLLPIDIDSDNRL
                     DTKVEELYLGFRNYFDSSTSARYGVLSDKQTIVINAGVLTNLAQNLQSSISGDLQTIR
                     HITEKCQAKNDAIKDSFEERKKRVSENIKALLATNGLTDTFNSLQSSLERLVGQQDLF
                     DMLSHSASLDYPFSYDEIPYVNNNRLNLAMYDSELASLNTKSLQLASSAQHEKSGWID
                     SIIGRSTLLKSWQIIDEASRQLLKESDKTFEGTGLRESKVDGISDSLKEVFSVELQDI
                     IELEKMIINTSELILGVSQNVTATDNWLGNSLKNGQFQGSADVVCVPSSYDAYLERTG
                     LLDDVRDILQAFDEQVEQKSRDYSRKVASVYASTFSRLFDTLDYWTTEVNIFKNIVTV
                     LERRFSDRVYVERTEIKDETSTTTRSYWGNLGALYPCRIRSGIASARAEVCPLVPALT
                     DTIQRVNTARHRLQNLHGDLSRLIEKGVYSALDLDDIITSQKMVGRLLDKIIVELSFV
                     KATIEASMSGQAASAMVNHLALLLKRLGYFSQLVADCFGTQVTKVPNKAPARASHKVK
                     RFSLNNPLALQ"
     gene            complement(12047..>12206)
                     /locus_tag="TV193_001347"
     CDS             complement(12047..>12206)
                     /locus_tag="TV193_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1513538.1"
                     /translation="INPMGGFSIHLIINDDPDTYLRVRLSRYDLERNLEIASNYRSEK
                     LEKLLKGE"
BASE COUNT         3765 a         2620 c         2275 g         3546 t
ORIGIN      
        1 ttacagcaat attgatattc caagttttct agcctgatat cagtgttttt tgagcttaag
       61 aagctcaaaa taaaaacaat gcctaagttc agacctgtgt aacagatgat ttaagcattg
      121 ttattattaa taaattctag ttgctacagc ctaacaaagg ggctgctgta atatagctag
      181 gtgagccttg agggactttt tagacagaaa aggaaaatcc ccaaaatgac taccaaaata
      241 atggctagag tgtcttttaa ttgccagctt agcaggcggt attttgttcg actgtcaccg
      301 ccttgatagc ctctagcctc catagcgatc gctaaagcgt cagctctttt aaagcttgaa
      361 gcaaaaagag gaatcaaaat agggataatc gactttacct tttgaataag attgccttct
      421 ccaaaatcaa cacctcgcgc tttttgcgca ttcataatac gagttgtatc gtccatcaag
      481 gttggaacaa accgtaagct caaagataac atcaaaccga tctcatgggc aggtacctta
      541 aacctaacta aaggcttcaa cagcgcttca acagcatcag ataagcttag tggggtggtg
      601 gttagggtta acagcgtgga aaagaaaata atcaaaacaa atcgcatgaa aatcaaaatg
      661 gcttgactta atcccaagct tgttatctta attattccaa gctgaaaaag aactgatcct
      721 ccctgtgtaa aaaaaacttg aaaaagcgtt gtaaatagga taataccaat cataggctta
      781 acaccattga aaaagaaaga ccattttatc tgtgacaaga aaatcagcag caagataaat
      841 gctaacagca aaagattagt taccacatta ttggcccaaa aaataatgat aatatagata
      901 atcatagcaa gcagcttgct tcttggatca agccgatgaa taattgaatt cccaggaata
      961 tagcgaccaa gaatgagttt atccatgctt taatacctct cttaattcct ccaaagtaat
     1021 gggtaaatag ggtaaatcaa agccttgctt agccaggcgt tgggcaaagg ctgtcacctt
     1081 agggacacct aattgttttt cttttagcaa atcaatgtgt tgaaaaatag cctttggctg
     1141 acctgataag atgattttac cagcttcaag gacataaaca aaatcagcat aattagcaac
     1201 atcgtccatc agatgtgtca ccagtacaat ggtcatgcct gattgatgga gcgatttaaa
     1261 aagactcatt aattcctttc gccctttggg atcaagccca gcagtaggct catctaacac
     1321 caaaatatcc ggctgcatcg caagaatacc cgcaatagca accctgcgca tctgcccacc
     1381 agaaagctca aatggatttt taccaaatag ttcctctgaa atccctacta gggttaattt
     1441 ttcacgcgct aaagcttccg cctctttctg agaaacacca aaattttgtg gtccaaaggc
     1501 aacatccttc aaaaccgttt cctcaaaaag ctggctctca ggaaattgaa agactagacc
     1561 aacctgctta cgaataggct taatatcttt attttttgac tgactagtta tctccttgcc
     1621 tgctaccgta accttgccgg tggtcggcag atgcaagcca tttaagagct gcataatcgt
     1681 tgacttgcct gagccagtat gaccaataaa agccgtataa gagccgtcta caatatcaag
     1741 attaacgtca aaaagggcac gcccctcaaa gggtgtccct gcttgatacg tgtagcttac
     1801 attttggaaa tgaattgaca tagctgttcc tctaattcct tttctgtgag atagattccc
     1861 tgtatagggt agccgtcttt ttttagcata ttaacaacag aggttgtaaa aggaatatct
     1921 aaacctagat tgatcaattg attgccccta gcaaatagct cctgtggagt cgagacagac
     1981 tcaacacgcc cattgttcat caccaaagct cgatcactaa gagccacctc atcaagatca
     2041 tgtgtaatag atataacagt tagttggtat tcttgtctaa tagattgaat tgtccgaatc
     2101 aactccagac gcccctttgg atccagcata ctggttgctt catctaaaat gatgatcatt
     2161 ggccgcatgg caacagcacc tgcaatagca acccgctgct tttgaccacc tgataatctg
     2221 gaaggctcct tatccttaaa agcctccata ccgaccagct gcaacgcctg atgaacacgc
     2281 tctatcatct cctgatggga aacacctttg ttttcaagac caaaagcaac gtcatcttcg
     2341 acagttgcac caacaaattg gttatcagga ttttgaaata ccatgccaat tttatgacga
     2401 atgtcccaga cattgtcctc tgtaagaaga tcaccatcaa caaaaatctg gccggcttct
     2461 gctttcaata gcccatcaat taacctaaca acggttgact tgcctgagcc attatgccca
     2521 atgatagaca accactcgcc ttgtttcaca tgaaacgtca catcatctag ggtatatcgc
     2581 tcctggtcct gcttatactt aaatgtaaga ttcttaactt caataatatt tgacattgtt
     2641 atttaaaggt atccttaaaa agaaagcttg ctcctttgaa ataatcgtaa cctgaataaa
     2701 tcgtaaacaa tagagcaata tacagcaaaa cagtgcctaa aacagtccaa tgacacagta
     2761 aaaagatgat ggaaagcatc tgtgctactg ttttgatctt accaggcata gcagctgcta
     2821 ggaccttatc tccagtctca accaatagca aacgaagtcc tgtaacagct agctcacgac
     2881 agataataac cgctgacacc caagccggta ccagctctaa gcccactaac ataataaaag
     2941 cactcatgac aagcatcttg tctgccaatg gatcagcaaa tttaccaaaa ttagtaacaa
     3001 cctgccactt acgtgcaagg taaccatcta aataatcggt caggcttgcc actgcaaaaa
     3061 taatcgctgc aaaggtatgc caaccgactg tctttgaaaa agaggtgatc aacaaaaaca
     3121 atggaatcat gacgatacgg gcgagagtta acaaattggg aatattttct tttttgatca
     3181 tgcttatacc ttattattgt atcttcagtg tgatatagct gatatcagta cttgtcattg
     3241 ctgataaatc taggggctga ccatcaattg ctactgaaac accctttgtt acgcctagtg
     3301 tcaacaagga ttctgttgtc tcagcaggca aggtagtaga ataagtcgga ttgtcctttg
     3361 ttagggtcat accagcctca ccaatttccg aattagtgag ggaaatccaa ctgctctcag
     3421 catcagtcag tgacactgta acatcaacag cttcttttga tttagtaata ttagcaatca
     3481 agtaattctc tgcgccctct gttgtgatca ccgtcttagg ctcagatgag ctggacgctg
     3541 ttgagtgact gctttgtgat gacttaagaa aagacatctc agcctctttt gctttttgac
     3601 ctttatcaaa ttgcttccaa acagcaaaac caataacacc aacaatagcc acagcaataa
     3661 gacctagtaa ggctgatgga aaggctgatt ttttcgtttt agcactattt ccataacgac
     3721 ttagccttga agcactggtc tctctagtcc gtctatggtc agtagcctta aagtgactag
     3781 ctgtaggagc tgatttgctt gaggatagtg acgtcttgac aggaatcact agggtttctg
     3841 gttgagtcct tgaaggctct ggttgagcta ttttttcaga atagctattc tcttgtagcc
     3901 tttttttgct gagcttttct tcaacgattt gtgtgactga tggtgtacct gtttcctttt
     3961 taaagctcac ctgcagctga tacaagcgtt ttaagctatc aaagtctaag ccaacaatat
     4021 cagcatattg ctttagaaaa tgaccaaact tttcttctgg aatgattttg aactggtcaa
     4081 gctccattgc caatagataa tgcgaggaaa tgccagtttt agcttcaatt tcgtctaatg
     4141 ttatgttttt tccgacacgt gtttctctta ataattcacc gagacttgtt tctctcatac
     4201 gagtacctca aaaatattgt aataagacca ttataacaga ttttaagcta tttgggaaag
     4261 actgtaaaat ctgaagtagc tgcatgctca aaaaacaagc ttcctatttc gataatatcc
     4321 tttaaagcta gggtctcaat aatcctagga atatcaaaat aggtctcttg ctctgataaa
     4381 tgaaggctaa attggcttgc cagctgatca atagcgtcta agctttgcat aaaatcccca
     4441 tacatttcct ttttcactag ctctaagtgc tcctcattaa cgtctcttga gcatctaaaa
     4501 tcggaaatct tttttctaat gctgttagac attgcaatag gctgactagt atctgaagaa
     4561 atcaatacaa attggaaatc cctttgaatg tcaacctcta tatcaaagga gtcgtctatc
     4621 ttgccctttt cataccaatc ctgataggtt tttgacgtcc agccaaggag caccgctagg
     4681 agcagtctaa gagctacctg ataggtgagt agagaatact cgcttgacat tagctgaccg
     4741 cgaaagccga ctgctaattt ggcagtcgca acgtccatat caatagatct agacttgatc
     4801 acagggtagt aggtcaatgg agctatctgt acatcatact gcgtctgact tggttgacta
     4861 tcttgaaagg cttcaatagc tgtaaaggct tcttcaatgt caatatcgcc aataatcgtt
     4921 aagaccatgt tagaagggtg ataaaaataa gcatggctgt cagccaataa agagcctgta
     4981 atgtccctga tagactcctt ggtcccagca atatcaacag ctaagctggt attgggaaag
     5041 aggttctgta agataccact gtaagcctga taatcaggat cgtcctgata catctcaatt
     5101 tcttgagtga taatatgttt ttcacgatta accgactcct ctgtaaagct aggagctgct
     5161 acaaattcct gcaaaagtct cagactttct tgccattcat tgacagttga aaagaaatag
     5221 ctcgttttat caaaggttgt aaaggcattt gtttctgatc ctaactgtgt aaatgtaaga
     5281 gcaatatcat taccatcttt atcctcaaat agcttgtgct ctaagaaatg agcaacacct
     5341 gacggcaagt caaacctttg acaattgact gtaaagcttg tgtcaagaga accaaaacga
     5401 gcagtcagca tagctgtttt ctcagaatag ccctctttct ttatcaaata aacccttaaa
     5461 ccatttgcca attgaccgta gtgtaaggtc tctttaatgc tgggatagtc ttttttcagt
     5521 agtgacgtca tcttattttc cctctaaaaa atatacagct tgcagcttga gtagattagc
     5581 tgtcctgaca atatctagct tgctaacctt gtcaatctcg tcaagccaac ttgacaaagt
     5641 ataggaagga tctatataag atctcatgta ttccagctca atcaaggctt tactattatc
     5701 ctcagatagc aaggcgttat tttttagcat tagctttgtt ttcttgacaa ggctgcttga
     5761 aaagcgcccc atcttgatgt cattgagctc tttaaccatt agctgcaggg ctcttgtccg
     5821 gtgctgtcta tctatgccag cataagcctc aaataagcct gtgtaaacat caaatcgact
     5881 accaatacta taggccagcc cctccttctc acgaatttgg gtaaagaagc gagagtgtgt
     5941 aaaggctcct aatagaccat ttaacacaac taaggcataa tactctgctt gcccataaac
     6001 cagcggaaaa tgataggcta gctctaaaac agactgatta agctgctttt gctcgaccaa
     6061 ttcgttgaca acattgacag gctgctgtaa ataaaagaaa tctagctttt tcctgcgtcc
     6121 ctcaaaggga aattggtgta acaattgtac catacgataa tcatcaaaat caccaagaat
     6181 aaaaatatca atctgatcct cattcaacat tttatgaaat tcttgatagc ttgtgtaggc
     6241 tgtttcttta gcaattaact cagtattacc atattttgac agcttcaggc tatcattagc
     6301 ataaaataat tgcttggctt ttagggcact ataataaaag gaatcctcct tatctgcctc
     6361 gacataggtc atcaaatgtc ttttttcgat gtcaaatagt ttgggctggt actgagccac
     6421 tgataacaaa ggagaaaaaa ggatatcctt tagaaattga atcatttcgt ctagaagctt
     6481 ctctccataa aaagcatact gatcctgaat aaaggtaatg tcaatatcca caatatgaac
     6541 caaacccttg gttgacacat gagttgacag gcttgctcca tacatttgtg ctaatttttc
     6601 tctaaattgc ttggcagtag gataggtatc gttagccgtt gctaacattt gagctactaa
     6661 gactcgcttt gctaccgttt tttgattcaa atcacctgaa aagcgaaacg ttatctgatt
     6721 cgttttaaat gttttgtttt ttatcagatg aagctgaact ccctgaataa gtttcataat
     6781 atttccttat taataaatgt gtgatctcta gaattatacc atttttatcg ctattcgttg
     6841 agtgttaaca tcagtctggt agcctatttt gactctttat caaaatgcta tcctgtggct
     6901 atagtctaga ctttagaagg tcagcatttc agcattatta tttagtggct ttttatgcta
     6961 taatgacttg aatgacaaat tggagatgac tatgacatac acactattta ctgactttat
     7021 taccctacaa gctttattaa aggagcaagg tattatccaa agtggtggtg ccattaaagg
     7081 ttttttagct caaacagagg tttttttaaa tggtcaagag gaacaacgac gtggcaagaa
     7141 gctaagagtc ggtgacgtca tcaccattcc atcacagcac atcaagattg agcttgtagc
     7201 gcctagtcag gccgaaaaaa cagcctatga agctgaaaag gcagaaaaag agcgagttgc
     7261 taagatggtt aaacaaatga atcaacaggc taaaaaagca cagaccaagc aagcagctac
     7321 taccaaaagc aagcgtggtc aagctacctc agctgtaaaa gctaagtcta atcaccaaaa
     7381 gcctattcgc ttcccaggat tgtagcatgt ggatcaaaga actaaacctc acccattacc
     7441 gtaattatca acaagcctca gcagcctttt caccgggctt gaatgttttc attggtgaca
     7501 atgcgcaggg caagacaaat tttcttgaag ctatttattt tttgtcagta acaagaagtc
     7561 atcgcaccaa atctgataag gacttaatct actttgacga aagggattgc tctatatctg
     7621 gaactcttga gcgccttagt ggtcgtgttc agctagaaat actgctgtct gataagggac
     7681 ggatcaccaa gattaacacc ctaaagcaag caaagctttc tgattatatc ggagcaatga
     7741 tggtggtcct ctttgctcct gaggatctac agctggtcaa aggctctcct aatcttagac
     7801 gaaaatttat ggacattgac ttaggtcaga taaagcctgt ttacttatca gatttgtcac
     7861 attacaatca tgtcctaaag cagcgaaatg cctatctcaa aagtgttcat cagcttgata
     7921 atgacttttt atctgtgtta gatgagcagc tggttaccta cgggagtcgt gtaatggcgc
     7981 atcggttggc gtttgttcaa tcactagcaa aagaggcaaa caagcatcat caagctatct
     8041 ctaatggcct agagaagctt tcgatctcct atcaagcctc tgtgagcttt gagcaccagc
     8101 aagagattta tcagcaattc atgaaccagc tcaaaaccac tcatcaaaga gatttcttga
     8161 gaaaaaatac tggtgttggc ccccaccgcg atgatctggt tttttatatt aatgacatga
     8221 acgctaattt tgctagtcaa ggccagcatc gtagcctgat tttatcactg aaaatggcag
     8281 aggttagtct gatgaagcaa ttaacaggtg acaaccctat tcttctactt gatgatgtta
     8341 tgagtgagtt agacaatacc agacaaacaa agcttctggg agctgtcaag aaagaaaatg
     8401 ttcaaacctt tatcacaaca actagcttag agcatttgtc tcagctacct aaggacatta
     8461 gtctctttaa ggttaataaa ggaacaatag aacgagattc tatcatgatt gattaactga
     8521 gcaaactaaa aaaagggcac cttaatagtg acccttttta cggttaaatt agttgatact
     8581 ctatgatttg acgataccta agaggatagc gccaacaata aagcaaagga tacctgtaat
     8641 gacccagcgc atctcttttt tggtttttgt ctcacctaag aataaaatac ctccgacaat
     8701 agagataata gcgcccaatt gtgaaaagct aaaagcaatc gccagaccag cctttgaggc
     8761 tgctagcagc atgaagatat ttccaactcc ccaaagcaag ccaacaacac tatttttgat
     8821 aacatactgg tcaaacgata ccttaaacga cataaacatg gctgcaccaa gcaccattcc
     8881 cactgccatc ggtaaaataa ccgacaacac atcaaatttc ataatgttat tgaacagcac
     8941 agcatacatc acatagccgg ttgtcgagta ggttaaggct ctaaagccct ttgaaaaatc
     9001 atgcaattga ttacttgctg cattcgtctc gtcctgcttg cttgaaaaat aaaaaccaac
     9061 aatcaaaaga agtaaggcaa tcgtaccaac gacaaattga ataggcttgg tccactcatg
     9121 aaagaccagc acaccaatca ggctacctaa aactagctga gaaccactag acaagggatt
     9181 tgctactgaa acacccatat actgcatggc atgaaattgc ccagtctgac caacagacca
     9241 gataatacca cctaaaatcc caaaaatcca gagcttcata gacatctcag gtctgactac
     9301 taaccaaaca actagagcaa atagtaaagc tcctatggtc attccaaagg tctgctgtga
     9361 gggtttaccg ccaattttat tactaacaaa gccaatactt ccccatgcaa acattgggac
     9421 aagtgcaaat aaaatacctt ccaaatttac atctccttta caataagttg acacatgatg
     9481 ttaacgataa aagtgctttc atacggagaa ttattatagc ctatttcctt agaaaataca
     9541 ataacatgat gtaaaaaatc atctgctcac acgcttctcc ctaaaaaggt gtcaaagtag
     9601 ctgacagagc ttatttactg caatgctaga ggattattta atgaaaaccg tttgacctta
     9661 tggctggctc tagctggagc tttgttaggg acttttgtga cctgagttcc aaagcaatca
     9721 gcaactagct gactgaaata gcctaagcgt ttgaggagta gagcaagatg attaaccata
     9781 gcactagctg cttgaccgga catgcttgct tctatggtag ctttgacaaa ggatagctca
     9841 acgatgattt tatccagcag tctgccaacc atcttttgac tagtgatgat gtcatctaaa
     9901 tcaagagcgc tgtaaactcc tttttcgatc aatcgactga gatctccatg caagttttga
     9961 agccgatgcc ttgcggtatt gactcgctgt atcgtatcag tcaatgccgg tactagagga
    10021 catacctcag ctctggcaga agcaataccg gatcttatgc ggcaaggata taaagcaccc
    10081 agatttcccc aatagctcct tgtcgttgta gaggtttcat ctttgatttc tgttcgttca
    10141 acataaaccc tatctgaaaa acgtctctct aatactgtca cgatattctt aaagatattc
    10201 acctcagtag tccaataatc aagtgtatca aatagccttg aaaaggttga cgcataaaca
    10261 gaggcaacct ttctggaata gtcccgactc ttttgttcca cctgctcatc aaaggcttgg
    10321 agaatatctc tgacatcatc taaaagacct gttctttcta ggtaagcatc atagctgctt
    10381 gggacacaga cgacatcagc acttccttga aattgaccat tttttaggct gttgcctagc
    10441 cagttatctg tagctgtgac attttgtgat acccctagga tcagctcact ggtattgatt
    10501 atcatttttt ccagctctat gatatcctgt aattccacgc taaatacctc ttttaaggaa
    10561 tcgctaatac cgtcaacttt actttcacgt aaacccgttc cttcaaaggt cttatcactc
    10621 tccttcaata gctgacgact ggcctcatca ataatctgcc aagatttcaa aagtgtcgag
    10681 cgaccgataa tactatcaat ccagcctgac ttttcatgct gagcagatga ggcaagctga
    10741 agcgattttg tgtttaagct cgctaattct gaatcataca tggccagatt gaggcgatta
    10801 ttattcacat atgggatctc atcataggaa aagggatagt ctaggctagc cgaatgagac
    10861 agcatatcaa acaagtcctg ctgaccaact aatctctcca aagaactttg caggctatta
    10921 aaagtatcgg ttaggccatt tgtagcaagc agggctttga tgttttctga aactcgcttt
    10981 ttcctctctt caaaggagtc ttttatggca tcattttttg cctgacattt ttcagtaatg
    11041 tggcgaatcg tttgcaggtc gcctgatata gaggattgaa ggttttgtgc aaggttagtc
    11101 aggacaccag cattgatgac aatcgtttgc ttatcagaaa gcacaccgta ccgagccgat
    11161 gttgacgaat caaagtaatt tctaaagcct aagtacagct cctctacctt agtgtctaat
    11221 cggttatcgc tgtcaatatc aataggcaac aggacattag catgaacaaa ccggccattt
    11281 acgtctgtca tgttgccata ttgatcatac tgatagccat gccacatatg ctgtaagact
    11341 atatcattga ccttttttgt attgacaaca aagacctgac cgactgctcc ctccttttgg
    11401 tcaaagccca taccaatgat gtcatgcgga tccacatagt tgtaaatgcg gtcatgcaag
    11461 agctttgcac gttttctttg atactcatta agcacacgat aggtgttggg gccattgtag
    11521 atatagactc cagagatacg agataagttt ttatcactaa cagaggtaac accgtactga
    11581 actgtcatgg agcctagcga atgaccataa aactcaaatg ttgcgttagg gtattgcttt
    11641 aatgtcttat tggtaaaggt tgctgccttt cggagctgag ctgtcccttt agttggtgtc
    11701 tggtccggta aaagaatgcg catagccata ggcaaatcat tgcctaccca atctgcaacc
    11761 acatctactg ggtgtttctg ccactggtct gggccagtag agccccggta cagcatggtg
    11821 acatgcttga cctgagcata gtctgccttg gtaggatgag ggggaagctt gacatctgtc
    11881 acgacatagg cttgaaaacc tgatatcgaa tcctctatct gagacacata accgatggaa
    11941 aactcagaat tatcatcatc aattaaaact ggtgaaccta ctgtatgttt ttcatactct
    12001 tcctcagcaa tccgttgtct ctgttcgtct gtcaggatca tcattttcac tctcctttta
    12061 gtagtttttc taacttttct gagcgataat tactagcgat ctctaaattt ctttctaaat
    12121 catatctact aaggcgaacc cttaaataag tatctggatc atcattgata atcaggtgaa
    12181 tagaaaaacc tcccattgga ttaata
//
LOCUS       DARYXS010000059        12203 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.060, whole genome shotgun sequence.
ACCESSION   DARYXS010000059 DARYXS010000000
VERSION     DARYXS010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12203
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.060"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(81..1361)
                     /locus_tag="TV193_001348"
     CDS             complement(81..1361)
                     /locus_tag="TV193_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1513539.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPF
                     RSVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGA
                     HGWIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLR
                     DWRVYSLIMIVLVAAQPDLGNASIIVLTAIIMFLVSGIGYRWFSAILVLITGLSTAFL
                     GMIAVIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDAN
                     EKKEDILKEAELSYRKSVREENSNSKIININQFQ"
     gene            complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TV193_001349"
     CDS             complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TV193_001349"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEL1513540.1"
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEE
                     IIDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTN
                     QDYLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRR
                     YRDVKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAIT
                     ALTSKYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRF
                     YIDKLSALYQTFSLSSALTKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQARLTQT
                     LQELIGQPASDQLASRMPATVGSLQSGVTSIVTNSSDQQAPAYKTAAAFKADLVMIEQ
                     SLIAAGDSSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENY
                     SALSEEQKCEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQ
                     HIISHTESVSDMFELAIMLKEVGLVDQRQARVQIVPLFETIEDLDNARAIMTQYLSYD
                     IVKSWIATNAGYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHG
                     RGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISAS
                     INRMVTRMLTNPDEIDGFRKIMDEIVEDSNRIYRELVFDNPHFYDYFFEASPIKEVSS
                     LNIGSRPVARKTITDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAK
                     LQHMYDKWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKN
                     VILAIAQHDELLEETPSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHT
                     TINGIATGLRNSG"
     gene            4550..6349
                     /gene="pepF"
                     /locus_tag="TV193_001350"
     CDS             4550..6349
                     /gene="pepF"
                     /locus_tag="TV193_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1513541.1"
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVGLFQRN
                     YEGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLAVLDELEKNPYFSATIRMAKIQKEHLLSPDVEKALTNLREV
                     INAPYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNG
                     LRKHQNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFG
                     PVAQKFLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTK
                     EVERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYTEEIGHD"
     gene            6342..6845
                     /locus_tag="TV193_001351"
     CDS             6342..6845
                     /locus_tag="TV193_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEL1513542.1"
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQA
                     LQELYDTYREQGFEILDFPCNQFLHQAPGDATEINAFCSLTYQTTFPRFAKIKVNGKE
                     TEPLFTWLKEQKSGPLGKCIEWNFAKFLIDQKGQVVERYASKTDPKMIEKALQQLLSQ
                     EPIDQSD"
     gene            7344..8537
                     /locus_tag="TV193_001352"
     CDS             7344..8537
                     /locus_tag="TV193_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1513543.1"
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYMIALSVGLLKVYNINAG
                     ELSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVV
                     VMYVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYATSNVLDIVSNFVGS
                     VLLGFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFR
                     ESTFTSFIILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVA
                     PRIKVSPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYS
                     EYNHNKLALIYTTNATLYAVFGVLFLLIPFVYSNIRVIGIVINSLTIMIGFGLLIVHL
                     QQERK"
     gene            complement(8736..9200)
                     /locus_tag="TV193_001353"
     CDS             complement(8736..9200)
                     /locus_tag="TV193_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513544.1"
                     /translation="MLRLAFSGFLIGQPVMALLLIYLLYVNVAEAILAMTGYVLLLAC
                     FFGFGPWLFWQMACYSMVLVLWGYFLNPLSDRLSQHRLINQALMAGVCTFCYHILLDS
                     CFAYLYSISWWSYIWAGMLFTVTNALATMGYFLVVLLLLKRLSGKKDPKLSA"
     gene            9468..10316
                     /locus_tag="TV193_001354"
     CDS             9468..10316
                     /locus_tag="TV193_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEL1513545.1"
                     /translation="MRRRIKPIVVVVFFTLIATLLIIGKAHSDNLKSKELKLAKASIP
                     TNTSTSNKSTTSTSETTEFLLNPIIDVSGWQLPSDIDYDLLASNISAAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKKHITEFQKRHIPVAVYSYALGRSAKEMRAEARTFYKNASPF
                     NPTYYWIDVEEATMTDMNKGVKAFREELKRLGAENVGLYIGTYFMAEQDISTEGFDAI
                     WIPTYGGDSGYYEAAPDTSLDYDLHQYTSQGYLNGFNNPLDLNQIAVTKDTKKTFEKL
                     FGKVKP"
     regulatory      10725..10821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10868..11431
                     /gene="thiT"
                     /locus_tag="TV193_001355"
     CDS             10868..11431
                     /gene="thiT"
                     /locus_tag="TV193_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEL1513546.1"
                     /translation="MSNKTTVTVLIEAAIFAALAMALSFIPDFAGWFSPSYGAIPLVL
                     FSLRRGLRYGLLTGLIWGLLHFILAKIYYLSLSQVIIEYILAFTSMGLAGLFSKPLTN
                     SLGTNKRSFSLLIASAAAFLAIGVRYIWHFIAGVIFWGSYAPKGTSAIWYSFTVNGTA
                     GLLTFIVTLIALLIILPTQPQFFKPSK"
     gene            11592..12071
                     /locus_tag="TV193_001356"
     CDS             11592..12071
                     /locus_tag="TV193_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEL1513547.1"
                     /translation="MAKKVKVKKTLVEQILDKAGIPYQALRINALQGDFPDTINPSDI
                     YKTLALTGDKTGPLIGIIPLTEHLSEKKLAGLSGNKKVSMIPQKELQKITGYVHGANN
                     PVGIRQRHNYPIYIDQSALAKQEIIVSAGELGRSIQINSQALADFVGASFADIKENK"
     gene            12068..>12203
                     /locus_tag="TV193_001357"
     CDS             12068..>12203
                     /locus_tag="TV193_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513548.1"
                     /translation="MRLIGNMIWFIFSGFWAWISWSIVGLILCLTIIGIPFGIQCFKI
                     G"
BASE COUNT         3668 a         2691 c         2355 g         3489 t
ORIGIN      
        1 caactttttg ggggcagtac acctggtcct ctctaaatgt ttgttataag ccacccgcta
       61 cagttgacaa ggagcttttt ttactgaaat tgattaatat taataatctt actattacta
      121 ttttcttccc ggacagactt ccggtaagat agctctgctt cttttaaaat atcctctttc
      181 ttctcattgg catcaatatt gaggacaaag ccaaccccta cagacaagac cagcaggctg
      241 tttcctccct gtgataagaa tggaaaggta acccctgttg aaggaatgag gccagaaatg
      301 ccaccaatgt taacaaatac ctgcatcagc atcatgccac caacaccaag agccatcatg
      361 gcgttaaagg gatttttggc cttaatcccg acattcatga ttctcaaaat aagaaagaaa
      421 acaagcgcaa ggatcaatcc tgccccaatc agccctaact cctcaatcac gacagaaaag
      481 acaaaatctg tctgtgcctc tgggagatag ccccgctttt caatcgaatt tccaagccct
      541 ctgccaaacc agccaccatt gctcatggcg taataagaat tagccagctg atgtcccgaa
      601 tctgtcaaat cacgaaaagg attgaaaaaa gcactaaagc gcttggcaac gtaaccaaaa
      661 actggaatct tagccacctt ttcaacacca atgacagcaa tcattcccaa aaaagcagtt
      721 gacaaaccag taattagcac taaaatggca gaaaaccaac ggtagcctat accactgacc
      781 aaaaacatga taatagctgt caacacgata atagaggcat tgcccaaatc aggctgcgca
      841 gcaaccagca caatcataat caaggaataa acacgccaat cacgcaggtc accccactct
      901 gttggccacc atttgcgacg cgtcaaggcc tgataatcat actgatgaat cttttcctgc
      961 atctttgaaa aggtgagtgc cagataccaa accatgatga tcttcagata ctctgctggc
     1021 tgaaacctca gaggcccaag gacaatccag ccatgcgcgc cattaatcgc tgtcgtaaaa
     1081 aagcgagcag caatcaacag cagtatttca agcagcataa caattgttaa aaccttggta
     1141 ttggtcaaaa aatttagctt tagcttgtaa ataaaggtaa tagcaactaa gctgacaacc
     1201 caaaagagcc cttgattggc aactgaccga aatggattgg cctgagcctg aatcaagcta
     1261 acactggttg tggaataaac catgatcagc ccaatcacag ataaaatcag ataaggtagt
     1321 aatatggagt aatttagcaa atgcctttta tcaattttca tcatttcccc tataatcttg
     1381 agataatcat tagcattata tcatctttca ttggtaaaac aaaggaaaaa tacattgcaa
     1441 gcacctagcc aagcatggct ctagacaaag cttgctgtat ccttggaatc gctcaatcta
     1501 aaaaacacag acaagccatt ataacctagt agcctgtctg tgtgagctgc tgattgatct
     1561 tcaacggctt agccggaatt acgaagtcct gtagcaatac cattaatagt tgtgtggatc
     1621 agcttttcat agtcctcatc tagctgctca tgacgaagac gcttaatcag ctcaatctga
     1681 atgtagttta acacattaaa atatgggagg cggaaatcca agctttgctt caaggacggg
     1741 gtttcctcaa gaagctcatc atgctgtgcg atagcaagaa taacgttctt agtcagctgc
     1801 cactcatcaa gaatggtatg aaagacctca cagacctcct tgctttctgc taactgcgca
     1861 tattgaaagg caatgttcat gtttgatttt gataatacca tatcaacatt agacagcaag
     1921 gaatgaaaga acggccattt gtcatacata tgctgtaatt tggctaaatt tccctcttct
     1981 ttatcaataa aacgcttaaa ggcagagcct actgcatacc agcctggaag catgatccgg
     2041 ttttgtgacc aagaaaatac ccaaggaatg gcacgcaggc ctgagatatc tgtaatggtt
     2101 ttacgagcaa cagggcgaga accaatattt aagcttgata cctccttgat cggactggct
     2161 tcaaagaaat aatcatagaa atgcggattg tcaaaaacca gctctcgata aatgcgatta
     2221 ctgtcttcaa caatttcatc catgattttc ctaaagccat caatctcatc aggatttgtc
     2281 agcatacgag tcaccatgcg attgatagaa gcagaaatca gcatttccaa attgtagtaa
     2341 gccacatctt gattgccata tttattttca ataatctcac cctgttccgt caagcggatt
     2401 cggtctttaa tagagccaaa tggctgtgag gtgatcgcct cataggatgg accgccacca
     2461 cgtccaacag tcccaccacg tccatgaaag aaggtgatgc tgataccatt gtcctcccca
     2521 attttggtca gctcattttg cgccttgtaa agtgtccagc cagacgctaa atagccaccg
     2581 tctttgttgc tatctgaata cccaagcata atctcttgat agccagcatt tgtagcaatc
     2641 caagacttga caatatcata gctaaggtat tgtgtcatga tcgctctagc attatccaaa
     2701 tcctcaatcg tttcaaataa aggcacaatc tgcacacgcg cctgacgctg gtcaacgaga
     2761 ccaacctcct ttagcatgat agccagctca aacatatcag aaacactctc tgtatgtgaa
     2821 atgatgtgct gcttaatcac ctcttcacca agcttatcct tgagctcacg tgccgctgta
     2881 tagatagcaa gctccttttc taacagctct gacttttcaa cagctgccga tgagagggtg
     2941 cgagggtctt ctgtcagctc ctttaagagg acctcacatt tttgctcctc tgacaaagca
     3001 ctgtaattct caacaatacc agcatttttc aaaagctcag caacacaggc ctcctgcaca
     3061 ctagaatcct gccgcagatc aatactggct aaaaagaaac caaaaatatc aaccgcttgt
     3121 aggacctctt gcaaatcccc ctcaaccaag gaggaatccc cagctgcaat gagagattgc
     3181 tcaatcatga ccagatcagc cttaaaagct gctgctgtct tataggctgg tgcttgctgg
     3241 tcactgctat tggtcacaat gcttgtaacg cccgactgaa gcgagcctac cgtagcaggc
     3301 attctagatg ctagctggtc tgaggccggc tgaccaatta gctcctgcaa ggtttgggtt
     3361 agacgagcct gaatatagtg aaaagctctg cggtagggct cattctcacg ataaatggac
     3421 tgatcactag atagactggc cagacgctcc acctcaggac tggtctttgt caaggctgac
     3481 gacagcgaaa aggtttgata aagagctgac aatttgtcaa tgtaaaagcg caggataacc
     3541 tcactttgga ctgttgcaga cagcctcagt gtctctgctg tgacaaaagg attgccatct
     3601 cggtcccctc cgatccacat gcccatgtta atcggctttg gattgtccag caagatcccc
     3661 ttgtccttgg ccagcgtctt atacttgctt gtcagcgctg tgatcgcctg tatcagagag
     3721 ctattgtaat actgcatgac attggtaatc tcatttttga ccttgagctt tttctcacga
     3781 atgatatccg tctgcatgag aatatcaatg taacggtaca gctcactata ccatttgttt
     3841 tgattcatga cacccgcctt gacatcacga tagcgacgaa gaaggttatg aatgctattg
     3901 gtcaactcta gaactgtctt tcgctgaacc tgtgttgggt gagctgtcaa gactggaacc
     3961 accgtcaccc tttccaacag ttccttggca ttttcctttt cagcagcaga agcaatggtc
     4021 agagcaagct ttcccagata gtcttgattt gtattgtttt gacgattgat ttcataagcc
     4081 aaatcaacgt cctctgaaat attaatcaac agcggaagaa tcgaaaaata tcgtgaaata
     4141 aattccatat ctttattgct aatcttagcg atcaattgct ctagaagcac ataatcctgt
     4201 ttttcagata ggtctataat ttcctcaatc cttgcaaagg cctcatcacc aatcatgcga
     4261 cgcgtaatgc tctcaagtat ttcctttagg atagcaacct cttcagcaat aatctcctga
     4321 ttattatagc tctctaattt tttgactgac aaatgacgga cttcccttct tatgctagtt
     4381 ttcctcctat cataccactt tttgctaaaa atgtaagcct attggctagg aatgtttgtt
     4441 ttccttgaca tataagattc attggtacaa aaatgtttgt aaagctttta caggctatcg
     4501 cttctaattt ttgttatact ataggtaatt actcatgaag gagaacatta tggaattaaa
     4561 aaaacgttca gaattccctg aaaatgagct ttgggaccta actgccctct acaaagacag
     4621 ggaagatttt ctattggcca ttgaaaaagc cttacaagat gtcggcctat tccaacgcaa
     4681 ttacgaaggc aaattaacaa ctgctcagga ttttacacag gccttgatgg agattgagca
     4741 gatttatatt caaatgagtc atattagcac ctatgccttt atgccacaga ccactgattt
     4801 ttcagatgaa gcatttgctc aaattgccca ggctggtgat gattttatga ccaaggctag
     4861 cgtagccctc agcttctttg atacagccct agctaatgca gaccttgctg ttcttgatga
     4921 attggaaaaa aatccctatt tcagcgcaac tatccgcatg gcgaaaatcc aaaaagagca
     4981 tttgctaagc cctgatgttg aaaaggcact gaccaatcta cgagaagtga tcaacgctcc
     5041 ttacgacatt tacaccaaaa tgcgggctgg agattttgag atggaggatt ttgaagttga
     5101 tggtaaagtc tacaaaaata gctttgtttc ctatgaaaac ttttatcaaa accatgaaaa
     5161 tgctgccatt cgtgacaagg cctttcgttc cttctcaaac ggactgcgta agcaccaaaa
     5221 tgcagcagcc gcagcctatc ttgctaaggt caaatcagaa aagctcttag ctgatatgaa
     5281 gggctatgcg tctgtttttg attacctgct ggctgagcag gaggtggacc gcagcatgtt
     5341 tgaccgtcaa atcgacctca tcatgaccga atttggtcca gttgctcaaa aattcttaaa
     5401 gcatgtggca agggtaaatg gcttagacaa gatgactttt gcagactgga agctagatat
     5461 tgataacgcc ctcaatccag aggtctctat tgatggagct tatgacttgg tgatggcatc
     5521 attagcacca cttggtccag cctatacgaa agaagttgaa cgctaccaaa cagagcgctg
     5581 ggtggacttt gctgcaaatg ccaataagga ttctggtggc tacgctgctg acccttacaa
     5641 ggttcaccct tatgtgctga tgagctggac aggccgtatg tctgacgttt acacgctgat
     5701 ccatgagatt ggccattctg gtcagtttat cttctctgac aatcaccaaa gctacttcaa
     5761 cacacacatg tcaacctatt acgttgaagc accttcaacc ttcaatgagc tgatgctaag
     5821 tgattatttg gaggcacaat ttgacacgcc tcgtcaaaaa cgctttgcac tggcgcaccg
     5881 cttgacagat acttatttcc acaacttcat cacgcatttg ttagaggctg cctttcagcg
     5941 taaggtttat accctcatcg aagagggggg cacctttggt gcagagcagc ttaatgccat
     6001 gatgaaggac gttttaacag agttctgggg cgatgctgtt gagattgatg atgacgctgc
     6061 ccttacctgg atgaggcagg ctcattatta catggggctt tatagctata cctattctgc
     6121 agggcttgtg atttcgactg ccggctacct caatctaaag aataacccaa atggtgccaa
     6181 cgaatggctt gatttcttaa agtctggtgg cagtcgtacc ccgcttgaga cagccctact
     6241 catcggagct gacatctcaa cagacaagcc gcttcgcgat accattcaat tcttgagcga
     6301 tacggttgat cagatcattg cctatacaga ggaaattggt catgactagc atttatgact
     6361 ttagcgttaa aagacaagat ggcactgatt gttcactgga gcaataccaa ggaaaggtcc
     6421 tattagtggt caacaccgcc actaaatgcg gattaactcc tcaatatcaa gcattacaag
     6481 agctttatga cacctacagg gaacaaggct ttgaaatcct tgatttcccc tgcaatcaat
     6541 ttttacatca ggcaccgggt gatgctacag aaatcaatgc cttttgcagc ttaacttacc
     6601 agaccacctt cccacgcttt gccaaaatca aggtcaacgg caaggagaca gagccattat
     6661 tcacttggct caaagaacaa aaaagtggcc cactcggcaa gtgcatcgaa tggaacttcg
     6721 caaaattttt aattgatcaa aaggggcagg ttgttgagcg ctatgcctca aaaacagacc
     6781 ccaaaatgat tgaaaaagcc ctacagcaat tgctttccca agagccaatt gaccaatcag
     6841 actaacgaag tcctatcaaa aaacaagcca agatccttat ttcttggctt gtttttatat
     6901 ctaaagcttc ttgctttgcc gaggagccgc taaaggtcgg ctatttgctt gtctattctt
     6961 caaagaactt ttttgaaggg gaccttgtcc tcacacctaa gcttactttt ttcaatcaaa
     7021 tcattcaagc tgcttcctgt aaggactggt gcacttgagc aatgataact tatgctagcc
     7081 tttttatgtt tatcaaaaag tacctgttca catgatttaa ggacatttac ttcagtcatc
     7141 aacagtaaaa agcattgacg catgtgatta ggattgttaa aatcatctta taaaattaag
     7201 aaaaacacat gactattgaa tgatctaagc tgtgctgcca aaagccctta cccttaatcc
     7261 tatcacagtg gacagcatgc aaatgacctc aggagtttca aatgacattc aaatagattg
     7321 tactgattgg agagtttatc agcatgagat ttcaagggtt aacaagtaac ttttataacc
     7381 tcatttttag taggtcaagt cgcaatatcg cagacagttt ttacatgatt gctttgtctg
     7441 ttggtttact taaggtttac aacattaacg cgggagaact ttcttttttg acattggttg
     7501 gtttattgcc aaatatgctg tcttttgctt atggttcttt aatccataac ttaaaaaatg
     7561 ataaaaaatg gttaattgtc tttcagatga tacagctcat tgtcatcatc agtattatca
     7621 tctgcttaag ctatcagcta ccggttgttg tcatgtatgt gctcaacctt gcctttaact
     7681 tggtcacaac cgtattaaat accattcaaa tgaaaatcgt tcccagaaca ctagacgatg
     7741 attcagacct cattgaaaaa tcagtagata ttcaatatgc tacatcaaac gttctagata
     7801 ttgttagcaa ttttgtgggc tctgttcttc ttggctttgt ttcctatctc gttttactgc
     7861 aattgagcct gcctttcttt ataggagcca tagcttttat ttttaggatt cagcttagcc
     7921 cgtctaagct tagcaccacg actaatgacg agattgaaaa acctgcttct gtaacagaat
     7981 cactacgtgc atttagagag tcgaccttta cttcctttat catcttggta gaagcctttc
     8041 tcagtggagg aaccgattta ttactagcac tccttccatt gtatctactg tctgagggca
     8101 tttcaatcga atacattggc cttgttttag cagctcacag agcagcagat ttattagggg
     8161 ctctggttgc acctcgcatt aaggtatctc cacgaagctt ctttttcatt gattatatcc
     8221 tgtctggaag cagcttcttg ctttgcttta tgattcccta tccgatggta aaattacttt
     8281 tgtttttcat taccttcacg attattggca tatcgggcaa tgtatttgaa aaaatgattt
     8341 atagtgagta taaccacaac aagctcgcct tgatctacac gaccaatgca accttatacg
     8401 ctgtctttgg tgtcctattt ttactgattc cctttgttta tagcaacata agggttatag
     8461 gaatcgtgat caacagcctg acaataatga taggatttgg attactcatc gtccatttac
     8521 agcaagaaag aaaatagctt agttctaaaa ccagcaaaat ggataaagcc cttcaacaaa
     8581 ataagcttcc ttacaaaaag gaatcagaag tcactattaa ataatcaaaa actatcaatc
     8641 gatataagaa gatttaagga gcaaaaaaaa gaaattactg atcggcaaca actgcactac
     8701 taccgggttg ctgcgtcaaa gccagcatta agaccctaag ctgacagctt agggtctttt
     8761 ttgccagata gccttttaag caataaaagc actaccagga aataacccat agtggctaag
     8821 gcattagtca ctgtaaaaag cattcctgcc catatatagc tccaccaaga gatactatag
     8881 aggtaagcaa aacaactatc tagcagtata tgatagcaaa aggtacagac tcctgccatt
     8941 aaggcttgat tgatcaaccg gtgctgcgat agcctgtctg ataagggatt caagaaatac
     9001 ccccacaaaa ccaataccat tgaataacaa gccatttgcc aaaagagcca aggaccaaag
     9061 ccaaaaaagc aggctaataa gagcacatag cccgtcatcg ctaaaatagc ctctgctaca
     9121 ttaacataga gtaggtaaat caacaaaaga gccatgactg gctggccaat gagaaagccg
     9181 ctaaaggcta ggcgcagcaa gaagcaacat acagaaacga tagctagtcg actaataact
     9241 ttggtagaca taatccctct ttgagtgttt tttatctatt atgacagatt ttgcatctct
     9301 tgaccagcat caacagcttt ttgatagatg attacaagac aggtagacta aaatcaaacg
     9361 aaaatagata ggacctgatc tgccaaagct gtcctaagga gctaaaaacc taagaaaatc
     9421 gtaagaccac tttgattttt tgaagcattt aaggtacaat aagactgatg agaagaagaa
     9481 taaaacctat tgttgttgtg gtcttcttta cgctgattgc tactttgtta atcattggaa
     9541 aggctcattc tgataatctc aaaagtaaag agctaaagct tgctaaagca agcattccca
     9601 ctaacactag cacgtccaat aagtcgacta caagcacatc tgaaactact gaatttctac
     9661 taaaccccat tattgatgtt tctggctggc agctgccaag tgacattgat tatgaccttt
     9721 tagcatctaa tatttctgca gcaattgttc gtgtttatgg cggatcacaa attactgccc
     9781 ataataacgc tgcctttact accgggattg ataaatcatt caaaaagcat attactgaat
     9841 ttcaaaaacg acatatccca gttgctgtct atagctatgc tctaggtcgt agtgccaagg
     9901 aaatgcgagc tgaagcaaga accttttaca aaaacgcttc tccttttaac ccaacctatt
     9961 attggattga tgttgaagaa gctaccatga cagacatgaa taaaggggtc aaggcgttta
    10021 gagaggagct aaaacggtta ggtgcagaaa atgttggcct gtatatcggt acttatttta
    10081 tggccgagca ggacatttca acagaaggct ttgacgccat ctggattcct acctacggtg
    10141 gtgattctgg ctattatgag gcagcgccag ataccagcct agattacgac ctgcatcaat
    10201 atacctcaca aggctacctc aatggcttta acaatccatt agatttaaat caaatcgctg
    10261 tcacaaaaga cactaaaaaa acctttgaaa agctttttgg gaaagtaaag ccttaaaggc
    10321 atcgaagcaa gtcgtcaaaa cctttgaatg tcagtcattc cgaatgcctt aaaccctaag
    10381 ctcaaagccc aggtaagcca atcctaaaga aggttgctcc tattcttatt tctttaagaa
    10441 taaagaccct ttcatcaatc taagaaggct aaagattgct ggctgttaaa aaatgctata
    10501 ttgattcctt ctgacgtcaa tttgagcatt aaggacaact gtatttagaa gctgatattg
    10561 ataacaccaa tcactgcttg tttttggttt aaaggctggc tgttagctca gccttttttg
    10621 gtgtgatcag tttttgacta taccgctatg ccaactttgt ctcatgattt caaggccaaa
    10681 ttcttgacat tgctgccatc tcattttata atatagaaaa tataattatc acaaaggagt
    10741 gctttggctg agatcgcgta tgcgaaatcc taaggacctg atcttgttaa tacaagcgta
    10801 gggattgtga ccaatatcat tagcattgga aaacgattct ctttttgtgt gcaaaaggag
    10861 tttttttatg tcaaacaaga caactgttac tgttctgatt gaggctgcta tttttgctgc
    10921 tcttgctatg gctttatcat ttataccaga ttttgccggc tggtttagcc cctcttatgg
    10981 tgctattcct ctcgtcttat tttcgcttag gcgtggcctc aggtatggcc tgctaactgg
    11041 cttgatttgg gggctgctcc attttatttt agcaaagatt tactacctca gtctatctca
    11101 ggttattatt gaatatatcc ttgcctttac ctcaatgggc ttagctggcc tgttttctaa
    11161 gcccttgact aatagtctag gtaccaataa aagatccttc agccttctaa ttgctagcgc
    11221 agctgccttt ttagcgattg gggttcgtta tatctggcat tttatcgctg gtgttatttt
    11281 ctgggggagc tatgctccta agggcacctc tgctatttgg tattccttta ctgtcaatgg
    11341 cacagcaggt cttctaacct ttatcgtgac acttattgcc ctgctcatta tcctaccgac
    11401 acaaccacaa ttttttaagc ctagtaaata agacaagagt tcgaatcgga aaatcataaa
    11461 gctgaggcag gtctgtaaag gcctgctctt tctaagccta gaaaaaggat caaaaaagac
    11521 tttttttcag tctaatggta tactactact gttagactgt ttttgatatt gacacataag
    11581 gaagttaaca aatggctaaa aaggtaaaag taaagaaaac gctggtggag caaatcctag
    11641 acaaggcagg tatcccctat caagcgctta ggatcaatgc cttacaaggt gatttcccag
    11701 acacaatcaa cccatcagat atttataaaa ccctagcact gactggcgat aagacaggcc
    11761 ccttgattgg gattattcct ttgacagagc atttatctga aaagaagcta gcaggccttt
    11821 ctggaaacaa aaaggtctcc atgattcctc aaaaggagct gcaaaaaata accggctatg
    11881 ttcatggtgc aaacaatcca gttggtattc gacaaaggca caattaccct atttacatcg
    11941 accagtctgc actagccaag caagaaatta tcgtatcagc tggtgagctt ggtcgatcca
    12001 tacagatcaa tagtcaagcc ctagcagatt ttgttggggc tagctttgct gacataaagg
    12061 agaacaaatg agacttattg gaaatatgat ttggtttatt ttttcaggct tttgggcctg
    12121 gatttcttgg tctattgttg ggcttatcct atgcttaaca attatcggga ttccttttgg
    12181 gatacaatgc ttcaagatag gcg
//
LOCUS       DARYXS010000060        12201 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.061, whole genome shotgun sequence.
ACCESSION   DARYXS010000060 DARYXS010000000
VERSION     DARYXS010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12201
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.061"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            54..572
                     /locus_tag="TV193_001358"
     CDS             54..572
                     /locus_tag="TV193_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1513549.1"
                     /translation="MTNNIAKLIEESGKKIKSISEALDISYPTLSSYNQGIRKPKKEN
                     AQKLADYFGVSVAYILGIDEEKYAPSNLKIVTDSFKTSEITSVTPFKSDMEKLKKGIE
                     LGEIHLSMPLNEVFSDDFRRILSNYLMDYEETFIKDLIKFMNNQGQKSDIWKTWIQTE
                     EFQIRRADRDRK"
     gene            626..1717
                     /locus_tag="TV193_001359"
                     /pseudo
     CDS             626..1717
                     /locus_tag="TV193_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378871.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(1832..2224)
                     /gene="rpsI"
                     /locus_tag="TV193_001360"
     CDS             complement(1832..2224)
                     /gene="rpsI"
                     /locus_tag="TV193_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEL1513550.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(2244..2690)
                     /gene="rplM"
                     /locus_tag="TV193_001361"
     CDS             complement(2244..2690)
                     /gene="rplM"
                     /locus_tag="TV193_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEL1513551.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            complement(3229..4089)
                     /locus_tag="TV193_001362"
     CDS             complement(3229..4089)
                     /locus_tag="TV193_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1513552.1"
                     /translation="MTFVLMTDSTADLDSFWAKEHNIDIVGLTVECDGKVYKTVGPDR
                     LTSDALLAMMKSGSQPKTSQINVGQFEEIFRHYAADNQALLYIAFSSVLSGTYQSAVM
                     ARELVLEDYPDAVIEIVDSLAAAGGEGYLTMLASEARDNGKSLLETKAIIEGILPRLR
                     TYFLVDDLFHLVRGGRLSKGSAFIGSLVNIKPLLWIDASGKLVPIAKIRGRKKAIKEI
                     ADRATKDIADSTVVVSYTSDQTGADDLREQLLAHEGISDVFMLPLGPVIAAHTGPDTL
                     AVFVIGKEKR"
     gene            complement(4273..4791)
                     /locus_tag="TV193_001363"
     CDS             complement(4273..4791)
                     /locus_tag="TV193_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEL1513553.1"
                     /translation="MKKRLLLVDGYNMIAFWESTRQFFKTNQLDQARRILLNKLNNYA
                     HFDDSDIICVFDAQYVPGLRQRYDQYRISVIFTEEEETADSYIERTAAELNTALTMVE
                     VATSDLNEQWTIFSQGALRVTAKELEQRVNAVKSDLDKLSQDIDLKKPRLGPFDQGQL
                     NQLKDFMNRLDD"
     gene            complement(4792..5538)
                     /gene="rlmB"
                     /locus_tag="TV193_001364"
     CDS             complement(4792..5538)
                     /gene="rlmB"
                     /locus_tag="TV193_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEL1513554.1"
                     /translation="MKAKEINETKDIVYGVHAVTESLLANTGNKLYIQEDLCGKHVDH
                     IKDLATSKKVSISWTKKKALTEMTAGAVHQGFALRVSAFAYTELDELLELAQQEDNPL
                     LLILDGLTDPHNFGSILRTADATGVCGVIIPKHRAVGVTPVVAKTSTGAVEHVPIARV
                     TNLSQALDQLKANGFWVFGTDVTGTPSYKWNTSGKLALIIGNEGKGISANIKKQVDEM
                     ITIPMMGHVQSLNASVAAAILMYEVFRNKL"
     gene            complement(5587..6375)
                     /locus_tag="TV193_001365"
     CDS             complement(5587..6375)
                     /locus_tag="TV193_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513555.1"
                     /translation="MKPMRNVALVISAMLLLSSQAFVSAVAAQDNQPTIAVQAQAAAE
                     ANVSARMRSDQPVIEANIATSQPVSQSTEATILLKDAKGNAINSTAYTMQAGQSRFSV
                     WFDLTNLKVSDYSISVSVPDKEKAFSGSSAPIHFDGKPTKNTPETEQKNSNPVPANNQ
                     PKPAASGRVTSTEQPQNVPSATASANHMTRTNHRSDKVLKASSSNTPSAAKSIDSAEK
                     GKGMLSDSTAQDKEQKGFPWLLSSLIAITAAALLALVIKAVHRK"
     gene            complement(6592..6999)
                     /locus_tag="TV193_001366"
     CDS             complement(6592..6999)
                     /locus_tag="TV193_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEL1513556.1"
                     /translation="MANSVDVNLINGIALAFVGDAVYSYYIRRHLIFQGQTKPNKLHY
                     LATKYVSAKAQASLIQAMLEAQLLTEKEKDIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAIMGYLDMTGQTERLELLIQWCIKQVENSPQS"
     gene            complement(6992..8335)
                     /locus_tag="TV193_001367"
     CDS             complement(6992..8335)
                     /locus_tag="TV193_001367"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEL1513557.1"
                     /translation="MIKIYDTMTRSLREFVPITDKVVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYAGYTVNYISNFTDVDDKIIKAAKESGVSPKELADRFIAAFMEDTKA
                     LGVKPATKNPRVMDYMDEIIAFIAALIKKGYAYESAGDIYFRVAKASNYARLANKTIA
                     DLEAGASGRTDTETALKEDPLDFALWKSAKLGEISWASPWSAGRPGWHIECSVMATEL
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTSKTFANYWMHNGFVNVDNEKMSKSLGNF
                     VTVHDLLKTVDGQTLRFFLATQHYRKPINFTEKAIHDAGVNLKYLKNTLQQPTVATAD
                     ASQLAAFITAFKAAMNDDFNTANGITVLFDMAKWINSGAYSEAVKSAFEEMLAVFGIV
                     FEAESLDTEIEQLIAERQEARANRDFARADAIRDQLAAQGIKLLDTKEGVRWIRG"
     gene            complement(8453..8989)
                     /gene="cysE"
                     /locus_tag="TV193_001368"
     CDS             complement(8453..8989)
                     /gene="cysE"
                     /locus_tag="TV193_001368"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEL1513558.1"
                     /translation="MGWWKDNIDIVKQLDPAARSTLEVILTYPGLKALAAHRLSHFLW
                     QHGFKLLARMHSQFWRFWTQIEIHPGARIASGVFIDHGAGLVIGETAIVEKGAMLYHG
                     VTLGGTGKDRGKRHPTVREGALISAHAQIIGPVEIGKSAKVGAAAVVLTDVPAGVTVV
                     GIPAQIVRVHEKKPSRQD"
     gene            complement(9001..9753)
                     /locus_tag="TV193_001369"
     CDS             complement(9001..9753)
                     /locus_tag="TV193_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEL1513559.1"
                     /translation="MTNTNELDIRLRAFINAPDNFLDSVALVNAFHQYPVWAAKKPYA
                     IEIEGVRIFPVFTDKDDMATFKEEQKSAQAQYWVERSALTVLEEAVHAGAAGLGFNLK
                     KKGDFGNSTVFKSADMIQFMNNYTTILNTLMSDDNSAADTLDRLYLVPAFVYPKEEEH
                     YYDRLFPTMSTPEGKRYVPAFSNLQSFAKWYNQEEFGGLFRKSGGVILTWKIADIYQP
                     RNGNNDIDETFGVAIDPFDDQQILVDWSDIDT"
     gene            complement(9746..11890)
                     /gene="pnp"
                     /locus_tag="TV193_001370"
     CDS             complement(9746..11890)
                     /gene="pnp"
                     /locus_tag="TV193_001370"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEL1513560.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKRANGATVVRYGESTVLTAAV
                     MSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFI
                     INPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQE
                     EIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAIQVEEKKAREAATEAVKERVI
                     AAYEERYAADEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEI
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALAQVLPSLEAFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITAL
                     QMDIKIEGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIASLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTTNVSDVLEIGEEVDVKVIKV
                     DDKGRIDASMKALVPRPPKPEKSEAKKEGKHD"
BASE COUNT         3539 a         2833 c         2331 g         3498 t
ORIGIN      
        1 tggtattata ctttttgtat taaatgtggt agaatatcaa ttaggaggaa tctatgacta
       61 ataatatagc taaacttata gaagaaagtg gcaaaaaaat aaaaagtatc agtgaagcgc
      121 tagatatatc ctacccaaca ctatctagct ataaccaagg aatacgaaaa cctaaaaaag
      181 agaatgctca aaagttagcg gattattttg gtgtctcagt ggcatacatc cttggaattg
      241 acgaagaaaa gtacgctccg tcaaatttaa aaatcgtcac tgatagtttc aagacatctg
      301 aaattacttc tgtaacacct tttaaaagcg atatggagaa gcttaagaaa ggaatcgaac
      361 taggagagat tcatttgtct atgcccttaa acgaggtttt ctcagatgac tttagacgta
      421 ttctttctaa ctacttaatg gattatgaag aaacctttat caaagactta attaagttta
      481 tgaataacca aggccaaaaa tcggatattt ggaaaacatg gatacaaacc gaagagtttc
      541 aaattagacg agcagatcgt gacagaaaat agactaatat ttctcaatta cataagctcc
      601 gaaaacttag aaacggagaa ctgttatgtc tgtacacaaa taccaatcta caaaaggaat
      661 tacctatttt gttaaagttt accttggtct aaacgactac ggtaagaaaa aatattacac
      721 taaacgagga ttcaagacgc gtaaagctgc caaagctcat gaaactgctg ttaatcatca
      781 gctgaatagt ggaacttttg cccatcttac tgctcaaaca acctatactt accaagaact
      841 atatcaaagg tggtatgaag cttacaaaga taccgttgaa acaactactg cagctaaaac
      901 ggccgattta tatcgccttc atattcttcc aacctttgga gagaaaaaga tttcaaaaat
      961 cagtccgcta gactgccaaa cctttatcac agataaagcg aaatcattca agaacatgaa
     1021 gcaaatcaag tcatacacct ctaaaacctt tgaatttgcc atcaatatga atcatattga
     1081 acgtaatcct atgagcaaag ttattatgcc taaactcaaa aaaactgtca gtgagaacta
     1141 ctggacagtt aacgagttgc atcatttttt gacaatcatt ttagaaaatg aaccttataa
     1201 acattatgct ctatttcgat tactagcata cagcgggtta cgaaaaggag agctctacgc
     1261 cctcaaatgg gaagattttg attctgagaa tcaactatta acagtcagca aaagtttagg
     1321 aagaatagat ggtcatgcca ttgaaaaagg aactaaaaat acattctcag tacgctctat
     1381 ctatcttgat gatgaaacct gttctatcct caacaaatgg aaacaggaaa ctagcaaaga
     1441 aaaggggcaa ttatcagtac agcccctttc tctcgacaaa gaatttatgt ttacatactg
     1501 caacagagat ggtgagatag aacccttaca cgctgactat atcaacaata ttctaaaacg
     1561 cattatacga aagcataatc ttaaaaagat tagcccacat gggtttaggc acactcacgc
     1621 aaccttgatg attgaaatgg gaattgaccc agttaatacc gctaagcgtc taggtcatgc
     1681 tagcagccag atgactttag atacttatag tcattctaac ttaacctctc ttaaaactag
     1741 gtctcaacag attaccaagg tgcttttttc aacaaaaaag caccttgcga aaacttcgca
     1801 aagtgctctg aaacgttggt ataactggat attaacgttt tgagaactgg ctagctttac
     1861 gggctttttt aagacctggt tttttacgtt caaccatacg tgcgtcacgt gtaagaagac
     1921 cagcgcgctt tagtgagtca cggaaatctg ggtccacttg aagaagcgca cgagcgatac
     1981 catgacgaat cgcacctgat tgaccagcat aaccaccacc tacaacgtta acaaaaacgt
     2041 cgtatgagcc ttcagttgaa gtcactgcaa aaggctgatt aatgactaaa cgtaggtcag
     2101 catgtgggat gtattcttca acatcttttt tattaacagt gattttacca gtacctggaa
     2161 ctaaacgaac gcgtgcaaca gcgtttttac gacgaccagt acctgcatat tgtgcttgtg
     2221 ccattattta atgctccttt ctcttagata agtcctgaaa tatcaagtac ttctggttgt
     2281 tgtgcagcat gagtgtgctc accgccaaca aagaccttta atttcatacc ttgtgcacgt
     2341 ccaagagtgt tgtgtggaag catgcctttt actgactttt caatcaaacg aacggcattt
     2401 ttagagcgaa gctcaccagc agtgattgat ttcaagccac ctgggtacat tgagtgagtg
     2461 taataaacct tatcagttgc ttttttacca gttaatttaa ccttctcagc attgataaca
     2521 ataacaaagt cacctgtatc agtgtgcggt gtgaaagttg gcttgttctt tccgcgaagt
     2581 acgctagcaa ctactgcaga aaggcgtcca agtggcacat ctgttgcgtc aacaacgtac
     2641 catttgcgtt caacttggcc tggtttagcc atgaaagttg ttttgttcat gatttctcct
     2701 atacgaattc gtttttgttt acattagtga tggatgttcc ggtccatcga aggtatttgg
     2761 aaggttccgg ggcctttcaa atggggtaaa caataccgtc tactatagta tcaaacttct
     2821 taactgatag tcaagtggtt tagctctatt tctttgatta tttttgcttt ttcacaagaa
     2881 gaacaggctt gcttttgagc tggactatta gccttgactt ccctccaaaa aatccgctca
     2941 gttcctgtta gctcctatgc aaataacaat acaaagatta gtggtggaat gaccaaagct
     3001 cctgtcaact gctaaaacat ttgacatctg acttctggca aatcaaaaag ccctgttctg
     3061 ttatgctagt tccttacctg cacgcgcacc ttcattgtca aacaattcat tctaactttt
     3121 gattaaaaat aaaaaatgcg aacacccata ctcttaagcg gcatcacagc taaaacaagc
     3181 tatagtcgac aaaaaagaat tgaaacaagc gcttcaatcc ttttcttttt atcttttttc
     3241 cttgccgatg acaaagaccg ctaaggtatc tggacctgta tgagcagcaa tcaccggtcc
     3301 gagcggcagc ataaagacat cactgatacc ttcatgtgct aatagctgtt ctcgtaggtc
     3361 atctgcccca gtctgatcac tagtatagga cacaacaaca gttgaatcag caatatcttt
     3421 tgtggctctg tcagcaattt ccttaatggc ctttttacgg ccacgaatct tggcaatagg
     3481 aactaatttt ccgctggcat caatccataa gagaggctta atattcacta ggctgcctat
     3541 aaaagcagag ccttttgaca agcgtcctcc tcgcacaaga tgaaaaagat catctactaa
     3601 gaaataggtg cgtaagcgag gcaaaatacc ttctattatc gctttggttt ctaataggct
     3661 ttttccatta tcacgcgcct ccgaggctag catggtcaaa tagccctctc ctcctgctgc
     3721 agccaagcta tcaacaatct caattacagc gtccggatag tcctccaaaa ccagctcacg
     3781 tgccatgaca gcactttgat aggtacctga taggactgaa gaaaaggcga tatataaaag
     3841 agcttggtta tcagctgcgt aatgtcgaaa aatctcttca aactgaccaa catttatctg
     3901 gcttgttttg ggctggctcc cacttttcat catagctagc aaagcatcac tcgttaatct
     3961 atctggacca accgtcttgt aaaccttgcc atcacattca acagttaggc ctactatatc
     4021 gatgttatgc tcctttgccc aaaaagaatc taaatccgct gttgaatctg tcatcaatac
     4081 aaatgtcatc tgaactccca agtaacgtca ttatcgttta ataatcaaat gattttctca
     4141 tagtataaca aaaaaatatc agctaagaaa gcaataagaa ccagctgcct cagaaatgat
     4201 caccgttaga tcgtatgagc tgctctagca gcctggagaa tcatacctag aaaagctagc
     4261 aagataagct tattaatcat ctaatcgatt cataaagtcc ttgagctgat taagctgccc
     4321 ttgatcaaag ggacccagtc taggcttttt aagatcaata tcctgtgaca gcttatctaa
     4381 atccgactta acagcattaa cacgctgctc aagctcttta gcagtgacac gcaaggcgcc
     4441 ttgggaaaag atcgtccact gttcattcag atcactagta gccacctcta ccatggttag
     4501 agcggtgttt agctcagcag cagtccgctc aatatagcta tcagctgttt cttcctcttc
     4561 ggtaaaaata acagaaatcc tatattggtc ataacgctgt ctaagtcctg gaacatactg
     4621 agcatcaaat acgcaaataa tgtcactatc atcaaaatgc gcatagttgt tcagcttatt
     4681 tagcaagatc cttctagctt gatccaattg gtttgtctta aaaaactgac gagttgattc
     4741 ccaaaaggca atcatgttat agccatcaac cagcaatagt ctttttttca tctataattt
     4801 atttctaaat acttcataca tcaaaatagc agctgcaacg ctagcattta agctctgaac
     4861 atgacccatc ataggaatgg taatcatttc atctacctgt tttttgatgt tagctgaaat
     4921 gcccttaccc tcattgccaa taatcaaagc cagcttgcct gaggtattcc acttgtatga
     4981 tggtgtacca gttacatctg tcccgaagac ccaaaagcca tttgctttta gctgatccaa
     5041 tgcttggcta agatttgtca cgcgagcaat tggaacatgc tcaacagctc ctgttgaggt
     5101 cttagcaacc actggtgtca caccaacagc acgatgctta gggataatca caccacaaac
     5161 acctgttgcg tcggctgttc ttaaaataga cccaaaatta tgaggatctg tcagcccatc
     5221 taggatgagc agcaagggat tatcctcctg ctgtgccagc tctagcagct catctagctc
     5281 agtataagca aaggctgaca ctcgaagcgc aaagccctga tgaacagctc ctgctgtcat
     5341 ttcggtcaaa gctttctttt ttgtccaaga gatagacacc ttcttactag tggctaaatc
     5401 cttgatgtga tcaacatgct taccacacag atcctcttga atgtaaagct tatttccagt
     5461 attggctagt aggctttcgg taacggcatg gacgccataa acaatatcct tggtttcatt
     5521 gatttcttta gctttcatgg tttttattat accacgaaag caataaaata gctcttgctg
     5581 ctctttttat ttcctgtgaa cagctttgat gacaagagca agtaaagcag ctgctgtaat
     5641 tgcaattaga gatgatagca gccaaggaaa gcctttttgc tctttatctt gggctgtgct
     5701 atcagaaagc atgcccttgc ctttctcagc agagtctatt gatttggcag ctgatggtgt
     5761 gttgcttgag cttgccttta ggaccttatc agatcgatga ttggttcttg tcatatgatt
     5821 ggcgctagca gtcgcgctag gcacattttg gggttgctca gtgcttgtca ccctgccgct
     5881 agcagcgggt ttaggctggt tattagctgg tactggattg ctgtttttct gttctgtctc
     5941 tggggtattt ttggttggct ttccatcaaa atgaataggt gctgagctac cactaaaggc
     6001 cttttcttta tcaggaacac tcactgatat actataatca ctaaccttta ggttcgtaag
     6061 gtcaaaccat actgaaaacc ggctttgacc agcctgcatg gtataggctg tgctattaat
     6121 cgcgttgcct ttggcatcct ttagtaaaat agtagcctca gtgctttggc taactggctg
     6181 actggtagca atgttagctt caataacggg ctgatctgaa cgcatacgag cactgacatt
     6241 ggcctcagct gctgcctgtg cttgaactgc tatggttggt tgattgtcct gtgctgctac
     6301 tgctgataca aaggcctgtg agcttaacag taacattgct gaaataacta aggctacgtt
     6361 tctcattggt ttcatagaca ttctcctatc attttattat gactctttca ttataaacta
     6421 ttcggaaaat ttttcaatag ttttgttacg tttttgttac aaatatttat tttatgtttc
     6481 gtgtgtatct atattgtgac ataactttta aacacaacat aaaaacactc tcatgacttt
     6541 gagcgatggc agatcgctag tgacacagag aatgttttag atgattcatc attatgattg
     6601 aggactgttc tccacctgct tgatacacca ctggatcaac agttctagcc gttctgtctg
     6661 acctgtcata tcaaggtagc ccataatagc ttcaaagcct gttgacatac gataggttac
     6721 tacatcagca tttttagcct tggtatggct gttggtattg cggcctcgtt tgtagatgtc
     6781 tttttctttt tcggtcaata gttgtgcttc tagcatggcc tgaatcagag aagcctgtgc
     6841 ctttgcagaa acatattttg ttgcaaggta gtggagctta tttggcttgg tctggccttg
     6901 gaaaatcaga tgacgacgaa tatagtaaga ataaacagca tcaccaacaa aggcaagggc
     6961 aatgccatta atcaaattga catcaactga attagccacg tatccacctc acaccttctt
     7021 ttgtatccaa cagcttgatc ccctgagctg ccaactgatc ccgaatagca tctgcccttg
     7081 caaaatctcg attggcacgt gcctcctgac gctcagcaat cagctgctca atctctgtgt
     7141 ctaggctttc tgcttcaaag acaatgccaa aaacagctag catctcttca aatgctgatt
     7201 tgacagcctc agaataggcg ccggagttaa tccattttgc catgtcaaat aagactgtaa
     7261 tcccatttgc tgtattaaaa tcatcattca tggctgcttt gaaggcagtg ataaaggcag
     7321 caagctggct agcatctgca gtggctactg tgggctgctg aagcgtgttt ttcaagtatt
     7381 tgaggttaac tccagcatca tgaatagctt tttcagtaaa attaatcggc ttacgataat
     7441 gctgagtagc caagaaaaag cgtagcgttt gcccatccac cgtctttagc agatcatgaa
     7501 cagtcacaaa gttgcccagt gacttagaca ttttttcgtt gtcaacatta acaaagccat
     7561 tatgcatcca gtaattggca aaagttttgc tagtttttgc ttctgattga gcaatttcat
     7621 tggtatggtg tgggaattcc aggtctgcgc caccaccatg aatatcaatg gtatctccca
     7681 aaagctcggt tgccattaca gagcactcga tatgccagcc aggacgaccg gcgctccaag
     7741 gacttgccca agaaatctcg cctagctttg ctgatttcca tagggcaaag tccaaaggat
     7801 cttccttgag agcagtttcg gtatctgtac gaccactagc accagcctcc aaatcagcaa
     7861 tcgttttatt agccagtctg gcataatttg atgcctttgc cacgcggaaa taaatatcac
     7921 ctgccgactc ataggcatag ccttttttga ttaaagcagc gataaaggca atgatctcgt
     7981 ccatatagtc catgacgcgt ggatttttgg tggccggctt cacaccgagt gccttggtat
     8041 cctccataaa ggcagcaata aatctgtccg ccaattcctt gggtgataca cctgattcct
     8101 tggctgcctt gataatctta tcgtctacat ctgtaaaatt tgaaatgtaa ttgactgtat
     8161 agcctgcgta ttcaaagtag cgacgaatcg tatcaaaggc cacagccgaa cgtgcattgc
     8221 caatgtgaat ataattgtaa accgttggcc cgcagacata catattgacc accttatcag
     8281 ttattggtac aaactctcgc agacttctgg tcatggtatc atagattttt atcatcactt
     8341 ttcccttttg tttttatcct tttctcctag actgcgcaag ctgtcagcaa ctgaggtaag
     8401 catagggctc taactctccc gttttttggc tgactgcctc tagagaaaac tattaatcct
     8461 gccttgaggg ctttttctca tgcactcgaa caatttgggc tggaatgcca acgaccgtca
     8521 cgccagcagg tacatcagtc aacacaacag ctgcagctcc aaccttagcc gatttcccaa
     8581 tctcgacagg accgataatt tgagcatggg cagaaatcag tgccccctca cgaacagtag
     8641 ggtgccgctt ccctcgatct tttccagttc caccaagcgt cactccatga taaagcatgg
     8701 ctcctttttc aacaatggcc gtctcaccaa tcaccaagcc agccccatgg tcaatgaaaa
     8761 cacctgaagc aatcctagct cctgggtgga tttcaatctg tgtccaaaat cgccaaaact
     8821 ggctatgcat tcgagccagc agcttaaagc catgctgcca caaaaaatgt gacagcctgt
     8881 gcgctgccaa ggcctttaat ccagggtagg ttaggataac ctctagggtg ctacgtgcag
     8941 caggatctag ttgctttaca atatcaatat tgtccttcca ccagcccatt taaactcctt
     9001 ttatgtgtca atatcagacc aatcaacaag aatctgctga tcatcaaagg ggtcaatagc
     9061 aaccccaaag gtctcgtcta tgtcattatt gccatttctt ggctgataaa tgtctgctat
     9121 cttccatgtt aagataacac cacctgattt cctaaaaagg ccgccaaact cctcttgatt
     9181 gtaccattta gcgaagctct gaagatttga aaaggcagga acataacgct tcccctctgg
     9241 agttgacatg gttggaaaaa gcctgtcata gtaatgctcc tcttccttag ggtaaacaaa
     9301 ggccggcacc agataaagcc tatccagggt atctgctgcg ctattgtcat cactcatcaa
     9361 ggtattcaaa atcgttgtgt aattgttcat aaactgaatc atatcagcag acttgaacac
     9421 tgtagaattg ccaaaatctc cctttttctt gagattaaag cctagcccag cagcacctgc
     9481 atgaacagcc tcctccaaga cagtaagagc agagcgctct acccaatact gagcttgtgc
     9541 actcttttgc tcctctttaa aggtcgccat gtcgtcctta tctgtgaata caggaaaaat
     9601 ccttacccct tcaatctcaa tagcataggg cttttttgct gcccacaccg gatactggtg
     9661 aaaagcatta accaaggcca cgctatctaa aaaattatca ggggcattga taaaggctct
     9721 taaacgaata tctagttcat ttgtattagt catgtttgcc ttcttttttt gcttctgatt
     9781 tttctggctt tggcgggcgt ggcaccaagg ctttcattga tgcgtcaata cgtcccttat
     9841 catcaacctt aataacctta acgtcaacct cttcaccgat ttcaagaaca tctgagacat
     9901 tggtagtgcg gctccaagca atttcagaga tatgcaccag cgcatctgtc ttgtcaaaga
     9961 ggttaacaaa ggcaccaaat ttttcaatac ggacaacctt agcatggtag acctctccta
    10021 ccttagcctc acgtactagg ctagcaatga tttccttagc acgattgata gcgtcctgat
    10081 cacttgagta gattgaaaca tttccttcct catcaatgtc aatcttaaca cctgtctcag
    10141 caataatctt atcaatggtt tcgccaccct taccaataac caccttaatc ttatcaacat
    10201 caatcttgat ggtatcaatc tttggtgctg ttggtgccaa ttctggacga ggctcagcaa
    10261 tggttgcctc aatcaagtca agaatttcaa agcgagcctt tttagcctgc gccaaggctt
    10321 cttctaggat ttgaggggtg ataccttcga tcttgatatc catttgcagt gctgtaatcc
    10381 cttggcgtgt cccagcaacc ttgaagtcca tgtcgccaaa atgatcctct aacccctgaa
    10441 tgtctgttaa aacagtataa ttggtcccat cagagataag tcccatagca atacccgcaa
    10501 ccggtgcctt gatcggcaca ccaccagcca tcaaagcaag cgtccctgca cagatagagg
    10561 cctgcgagga agaaccgttt gattccaata cctcagccac tagacgaata gcatatggaa
    10621 atgcctcaag gcttggaagg acttgtgcaa gagcgcgctc gcctaaagca ccatgcccaa
    10681 tttcacgacg ccctgctgca ccgtagcggc ctgtctcacc aacagaatat tgagggaaat
    10741 tatagtggtg caagaagcgt tttttgtact caggctcaag cccatcaata atttgagtat
    10801 ctcccattgg ggctagagtc aagacagaca aagcttgagt ttgaccgcgc gtaaagaggc
    10861 ctgagccatg cacccttggt aagaaatcaa tctcagcagc aagcggacga atctcatcaa
    10921 cacgacgacc atcaggacga accttatcct cagtgatgag gcgacgaacc tcagcatgct
    10981 ccatttgctc caaaatttca gccacatcac gcatgatacg gtcatgctct tcgtctgctg
    11041 cataacgctc ctcgtatgca gctatgacac gctccttgac agcctcggtt gcggcttcac
    11101 gtgctttttt ctcctcaacc tgaatagcct gctgcaaatc agcattgtaa gtctctatga
    11161 tctcagcctg caaatcagca gcaacctgta atagctctac ctcagccttt tccttgccca
    11221 ccgctgcaac aatctcttct tgaaaagcaa tcaactcctg tatagcctta tggccaacca
    11281 aaagtgcttc tagcataata gcctctggca attccttagc accagattca accatattga
    11341 tcgcatcttt tgttcctgct acggttaact ctaataatga agcctcctgc tgggccttat
    11401 caggattgat gataaattca ccctcaacat aggccacctg aacaccagca atcggcccat
    11461 taaaaggaat atctgaaatc gatagggcta atgagctacc aagcatagca gccatagggg
    11521 cactagcatc ttcgtcataa gacaggacag tattaatcac ctggacctca ttacgaaagc
    11581 cctcagcaaa cataggacgg atagggcggt caatcaagcg agcggttaag gtcgcatctg
    11641 ttgacggacg tccctcacgc ttcatccagc caccgggaaa tttacctgcg gcatacattt
    11701 tttcttcata attgacttga agcgggaaaa agtctcctgt tgacatcttc ttagacatga
    11761 cagcagcagt tagcactgta gactccccat aacgaacgac agtggcacca tttgctcgct
    11821 tggctacttg accgacctca acaacaagtg gtttgcctgc aaaggttgtt gtaaatgttt
    11881 gttttgacat tctttctcct tgaacgagct agcctaccat agccgtttga cccgaccaaa
    11941 gcttgctagc cttttatttt ttatggctat acgttgtttt gctacaaaga gcaatctgta
    12001 aggaattaca cactcctctt tgtatcaaac gacgtatctg ctacatttta ccataaaata
    12061 gttaaaaatt cacgacccta aaaggcattc ctagaaaaag tttgaaaggg ctgtcaatac
    12121 cagcagcact ctcttttatc actatagccc tacagccaag cacgctaagc cgctgatgac
    12181 gcagcaaaaa aagacctgcc t
//
LOCUS       DARYXS010000061        12157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.062, whole genome shotgun sequence.
ACCESSION   DARYXS010000061 DARYXS010000000
VERSION     DARYXS010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.062"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(152..433)
                     /locus_tag="TV193_001371"
     CDS             complement(152..433)
                     /locus_tag="TV193_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEL1513561.1"
                     /translation="MTTQKAYMYVLECADKTLYTGYTTDLDKRLKAHNAGKGAKYTRC
                     RLPVSLLYYESFDSKQAAMRAEALFKKRNTRQQKLTYIAEQQNKKAKPD"
     gene            complement(466..1233)
                     /locus_tag="TV193_001372"
     CDS             complement(466..1233)
                     /locus_tag="TV193_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEL1513562.1"
                     /translation="MLHSILKDGERIDQLFSSDVQIIQNKEVFSYSIDSVLLSRFPKL
                     PSRGLIVDLCSGNGAVGLFDSTQTKASIVEIELQPRLADMGQRSIRLNQLEDQVTMIC
                     DDLTNLLQHVPRSGVDIILYNPPYFKSSQTSKKNLSEHYLLARHEITTNLAKICQIAR
                     HALKSNGRLAMVHRPDRFLEILDTLKINGLAPKRLQFVYPKLGKEANMLLIEAIKDGS
                     MEGLKILPPLIVHKDNGDYTDTIKEIYFGAKDKAFKN"
     gene            1352..2092
                     /locus_tag="TV193_001373"
     CDS             1352..2092
                     /locus_tag="TV193_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEL1513563.1"
                     /translation="MFYVYLRGLVVFLLWVVNGNAHYHNEDRILDKSENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFTNRLFAWWIKMCGAFPIDREKPSPDAIRYPVNM
                     LKKSNRSLVMFPSGSRHATDVKGGVAVIAKMAKVKIMPAAYQGPMTLKGLLAGERVDM
                     NFGHAIDVSDIKRMNDEEIEEVARRIQAEFDRLDQEMAPFKSNQRRSMLTYLYRIPLG
                     ILLVLILALTMLFSYLASFVWDPDKHRS"
     gene            2411..3091
                     /locus_tag="TV193_001374"
                     /pseudo
     CDS             2411..3091
                     /locus_tag="TV193_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            3072..5315
                     /locus_tag="TV193_001375"
     CDS             3072..5315
                     /locus_tag="TV193_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEL1513564.1"
                     /translation="MRFPLTKYFPIAPIQFALLVLVLHYLIYRPSWLTAGLLAGLLVL
                     LGYRFVLKQVLKTLLLLGLFGCLFAYQKGQLEANQINQPDRLSTVELIPDSIMVNGDH
                     LSFIGRHSGHHYQLAYRMTSKEEADFFKQQSQFLKLKADIRLEEAAGLRNFKGFNHQA
                     YLAYQGIFRVGKIKSLQSLKTISPRSVSDRISQWRRQAIVWCQSRFPQPMSHYMTGLL
                     FGYLDKSFGQMTELYSQLGIIHLFALSGMQVGFFLTYLRRGLVWLHIPIDKIKLLEVV
                     CSFCYSGLTGHSISVIRSLLQAQLRHIGLTGLDNLAMTFLMMFLINGHFLMSIGGVLS
                     FAYAFIIATVRFEELSGNKQRLLKALAISFGIVPLLAYYFSVFNPISVVLTALLAYLF
                     DGLILPGLAILFFFSPLAVVTAVNPFFLYLEKGIGMIGSYFSAPLVLGSPTALQLCLC
                     MACLAIVYDYRGNRGLQLVAGGLLLLTLFTVKWPMTNEVTLVDVGQGDSIFIRDKQNH
                     TMLIDVGGVPAPQEKEQWRRKYQACNAHKTLIPYLRSRGVDTIDQLVLTHTDTDHVGD
                     MEAVVKAFRVKQIYVSQGSLTNASFVKRLQGLAAKVKAISAGDHLPIMGSFLEVLYPW
                     EIGDGKNNDSLVLYGRLLDKSFLFTGDLEAEGEERLIARYPKLKADVLKAAHHGSKGS
                     SIPAFLDHIQPQLSLISAGRNNQYQHPNPETLARFEARHIPYYSTASKGAIRLTGQAH
                     WQLESCR"
     gene            5428..6489
                     /locus_tag="TV193_001376"
     CDS             5428..6489
                     /locus_tag="TV193_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEL1513565.1"
                     /translation="MIAIEKIDALSKESLGLITVVTGEDIGQYSHMKALLLKKIAFDP
                     ADLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIFDHLLDITTSKKSYLKEKELKAF
                     EDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
                     LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVF
                     DLTRLVLQGKIDAARELVHDLRLSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQL
                     VTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFD
                     LALLKLVAHSQGNTDLSDL"
     gene            6567..7172
                     /locus_tag="TV193_001377"
     CDS             6567..7172
                     /locus_tag="TV193_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEL1513566.1"
                     /translation="MTITLPDLPYAYDALEPYFDTETMTLHHDKHHATYVANTNTALE
                     KYPELGENLEELLADVSSIPADIRQAVINNGGGHLNHALFWELLSPEKQEVSADVAAA
                     IDDAFGSFAAFKEQFTAAATGRFGSGWAWLVVNKAGQLEITSTANQDTPISEGKQPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSEFYQAAK"
     gene            complement(7423..8637)
                     /locus_tag="TV193_001378"
     CDS             complement(7423..8637)
                     /locus_tag="TV193_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1513567.1"
                     /translation="MKYIHSGLMFLLFVLFVVSFAKHEQARLAFEQSHQAYKDMVISF
                     EKRHIKQQPSSLSDQFQLRKDLLHYAKKLAQDGWSYEAIEKGYLGHLKPKQASYNFEQ
                     LYQSLQIIGSPAFHRMWERQPRAQHKLEAKRDLSLLLSYVKMPEELSGQSAETKQLLK
                     QFSPSLSPTDAFWDQLASLIQLYYDHLEHIPYQTFNRKLYQLRYVLSVQQIEWVRNNY
                     GRAGKTDADALARYLATLDESDYSLNESARYHNKVASHLDTANQLQITYPDNFPQANY
                     KILIHFHSEFILSEAGHFLAALDPQQPSQNGLINGSSFNYANQNNDLHRLLDIEPIEL
                     FEPDFIETAMINLDSPFIVPDLEQQNDQQHPIFSRDGKSSKQLTKAAAKAFKKLLRHY
                     QQAHQSFPSKTP"
     gene            complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TV193_001379"
     CDS             complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TV193_001379"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEL1513568.1"
                     /translation="MNTNDFDFELPEELIAQTPLEQRDRSKLLIIDHQEHTMTDSHFD
                     HIIDQLEPGDALVMNNTRVLPARLYGEKMETHGHVELLLLKNIQGDQWEVLAKPAKRL
                     KAGAQISFGDGRLKARVIQELEHGGRIVEFSYDGIFLEILETLGEMPLPPYIHEKLAD
                     AERYQTVYAKENGSAAAPTAGLHFTQELLQKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     IDEHDMHSEFYLLSEEAAQTLRKVKAAGGRIIAVGTTSIRTLETIGSKFQGQILADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYKHAIDEHYRFFS
                     FGDAMFVK"
     gene            9943..10647
                     /gene="nagB"
                     /locus_tag="TV193_001380"
     CDS             9943..10647
                     /gene="nagB"
                     /locus_tag="TV193_001380"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEL1513569.1"
                     /translation="MKIIRVQDQLEGGKVAFSLLKESLAKGATTLGLATGSTPITFYQ
                     ELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMRDQLFNAKPFKESFLPNGLADDL
                     EAEVKRYDQVIAEHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRF
                     FASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQH
                     DNVVVIIDEAAASELD"
     gene            10819..11535
                     /locus_tag="TV193_001381"
     CDS             10819..11535
                     /locus_tag="TV193_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1513570.1"
                     /translation="MRLDKLLEVTGFGSRNQVKQLIKGRSVLIDGQPARAGCQSVDSG
                     LQVIMVNGRQIKAFAHRYYLLHKPAGVVSACSDRKHQTVIDLIRKEDRVANLYPIGRL
                     DRDTTGLVLLTDNGPLGFRMLHPKHHVNKTYLVTVNGSLAADAVPFFENGVTFLDGTR
                     CKSAALRIIKADQMESQAEVTLSEGKYHQIKKMFLSYGLKVTQLKRIGFAEIALGDLA
                     EGAYRQLTVKEKKLIKTYLT"
     gene            11627..>12157
                     /locus_tag="TV193_001382"
     CDS             11627..>12157
                     /locus_tag="TV193_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1513571.1"
                     /translation="MLTALDQDQRVISLTDGSSPSRKQAFTCPACGAAVRLKKGRIIR
                     PHFAHISLSHCQYLTENESHEHLRLKADLYRSLSRSETAEVEAYLPDLNQIADLLVNK
                     HLALEIQCSQLPIKRLEQRSRAYQANGYQVRWLLGRKLWLQKRLTGLQRQCLYFSWQL
                     GFHLWELDVEHHLIRLK"
BASE COUNT         3304 a         2348 c         2831 g         3674 t
ORIGIN      
        1 aagtccttgg aggttttgtt ttgctgcttt tttggtcttg gtctttagta gccttgggca
       61 agcggagctt tgacctagtg tgggtctgtc tcaactgttg tcagctagtc ccatagtggt
      121 gcttggccgc ggcttaggag gcgtcaggag cttagtctgg cttcgctttt ttattttgct
      181 gctctgcaat ataggtgagc ttttgctgtc tggtgtttcg ttttttaaac aaggcttcgg
      241 ctctcatcgc agcctgcttg ctatcaaagc tttcataata cagcaggctg acaggtaagc
      301 gacagcgtgt gtattttgct cctttaccag cattatgggc tttgagacgc ttgtctaaat
      361 ctgttgtata gccagtatag agggttttgt ctgcacattc taaaacgtac atgtaagcct
      421 tttgagttgt catgatgaaa aaacctcttg atgcagaaga gcctgctagt tcttaaaagc
      481 cttgtccttg gctccgaaat aaatctcctt aattgtatcg gtatagtctc cgttgtcttt
      541 atggacaata agtggtggca ggattttcaa gccttccata gaaccatcct tgatggcctc
      601 aatcaagagc atgttagcct ccttaccaag ctttgggtag acaaattgca gccgctttgg
      661 agcaagaccg tttattttta aggtatcaag aatctctaaa aagcgatcag gtcgatggac
      721 catagctaga cgaccattgg acttgagcgc atggcgtgct atctgacaga tcttagccag
      781 atttgttgtg atttcgtgtc tggctaggag ataatgctca gataggtttt tctttgaggt
      841 ctgactgctt ttaaagtaag gaggattata aagaatgatg tcaacacctg agcgaggcac
      901 atgctgaagc aggttagtca aatcatcaca aatcatcgtc acctgatcct ccaactgatt
      961 gagcctgata gagcgctgtc ccatatcggc taagcgtggc tgaagctcaa tttcaacaat
     1021 agaggccttg gtttgtgtac tgtcaaataa gcccactgcc ccatttcctg aacacaaatc
     1081 tacaatgagc ccacgtgatg gaagctttgg aaagcgagaa agcaagacac tatcaataga
     1141 gtagctaaag acctctttgt tttgaataat ctgaacgtcg cttgagaaaa gctggtcaat
     1201 ccgttcacca tcttttaata tcgaatgtag catatcatta ttatagcaaa aataatccta
     1261 tcagagtagg gggtgctgat tgagctttcc ctttaatatt aaaatatttc atggtacaat
     1321 gagtaggatt ataagtgaaa aggagactga tgtgttttac gtctatttac gtggcttagt
     1381 tgtcttttta ttgtgggttg ttaatggtaa tgcccactac cataatgagg ataggattct
     1441 tgataagtct gaaaattata ttctagttgc tccgcatagg accttttggg atcctgttta
     1501 catggcattt gccgcacgtc caaagcagtt tattttcatg gccaaaaaag agctcttcac
     1561 caatcgttta tttgcctggt ggattaagat gtgtggagcc tttccgattg atcgcgaaaa
     1621 gcctagtcca gatgccatta gatatcctgt taatatgctg aaaaaaagca atcgctcttt
     1681 ggtgatgttc ccaagtggga gccgtcatgc gacagatgtc aaggggggcg ttgctgttat
     1741 tgccaagatg gccaaggtca aaatcatgcc agcagcctat cagggtccta tgaccttaaa
     1801 gggcttatta gcaggtgagc gtgttgatat gaactttggt catgcgattg atgtttccga
     1861 cattaagcgt atgaatgatg aggagattga ggaggtagct aggcgtattc aggctgaatt
     1921 tgaccgctta gaccaagaaa tggctccctt taagtctaat caaaggcgct ctatgctgac
     1981 ctatctttac cgtattccat taggaatact tctggtgctt attttggctt taaccatgct
     2041 attttcttat ttagcaagct ttgtttggga tccagacaag caccgctctt aggtcgtgtt
     2101 atggattagc gctgaaggcg cgcaaaaatc agggctttgt tgctactcta ctgagactgg
     2161 cttgcagtta cccttctgac atgttatgtc taggatacga atgctactgg ttactcaagg
     2221 ctacaagaaa gccagcactt tccacagtaa ggggattagg taagccaagg taggttatgc
     2281 ttgtagtgta gctgtatgtt acaatttgat gaggttgaag aggtagtcca ttttggactg
     2341 ctttttttaa tatgctagaa aataggacaa ttttaaaggc ttttatcgaa taatatattg
     2401 aggtgaaaac atgttagaag aattgttctt aaagagtaaa gagatgataa agtcccctta
     2461 ttttctgtca cgttgtgtta ctggtgtgct gtctgtaggg cttttgctgg tgctgtggat
     2521 tgccttgact ggcaaggaaa aagcaagaga ggagtcagct ccatttcctg accattctca
     2581 ggttcagcag tcagaaaagc cagctcagct agaagctagt gagcaagaaa tggcggcagc
     2641 tgaggatatc gtagtggata ttaagggagc tgttcataag gagggtgtct ataagcttgc
     2701 taagggaagt cgtatcacag atctgattga gctagcaggt ggcttgacag accaagctga
     2761 taaaaatgct attaatctag ctgaaaagct atctgatgaa aaggtcgttt atgttgctaa
     2821 gctgggtgag aatatatcag tcattaaagg atcttcagct gaggctcaat cagcgtctgc
     2881 tgatcatcag aagcctgaaa aggttcattt gaacagagct agtcttgctg atttgcaaag
     2941 cattccaggc attggtgcaa agagagcata ggatattatt gatgtacgag aaagcctggg
     3001 tggctttaaa tctctagaag atctgagaaa ggtatcaggt attggtgcta aaacactgga
     3061 gaagctaaag catgagattt cccttgacta agtattttcc aattgctccg atacaatttg
     3121 cccttttagt gcttgttttg cattatttga tttatcgacc tagctggtta acggctggtt
     3181 tgttagctgg cttgttggta ttattaggct atcgctttgt cctcaagcag gtcttaaaga
     3241 cgcttctttt gctagggctt tttggctgtc tttttgctta tcaaaagggt cagctagagg
     3301 ctaatcagat caatcagcct gatcgcttat caacggttga gctgattcca gattcgataa
     3361 tggtgaatgg tgatcaccta tcctttatcg gtcggcactc ggggcatcat tatcagttgg
     3421 cttatcgcat gacctcaaaa gaagaggcag atttttttaa gcagcagagc caatttctaa
     3481 agctaaaggc tgacatcagg ctagaggaag cagcagggct tagaaatttt aagggcttta
     3541 accatcaggc ctatttagct tatcagggaa tctttagagt aggaaaaatc aaaagcttgc
     3601 agtcattgaa gactatctct cctaggtctg ttagtgatcg tattagccaa tggcgacgtc
     3661 aggccatcgt ttggtgccaa tctaggtttc cacagccgat gagtcattat atgacaggat
     3721 tgttatttgg ctatcttgat aagtcctttg ggcaaatgac agagctatac agccagctcg
     3781 gtattatcca tctgtttgct ttatctggta tgcaggtcgg cttttttctg acctacctgc
     3841 gtcgtggctt ggtctggtta catattccaa tagacaagat taagctactg gaggtggtat
     3901 gttcattttg ctattctggt ttgactggtc atagtatttc tgtgatacgt agcttgctgc
     3961 aggcccagct gcgtcatatt ggtttgacag gactagataa tctagcaatg acttttttga
     4021 tgatgttttt gattaatggt cactttctga tgtctattgg tggtgtcttg tcctttgctt
     4081 atgcttttat cattgctacg gtcagatttg aagagctttc tggcaacaaa cagaggcttt
     4141 tgaaagcctt agccatttcc tttggcattg tgcccttgct ggcctactat ttctcggttt
     4201 ttaatccgat ctcggtagta ttgacagcct tattagccta tttgtttgat ggtcttattc
     4261 taccaggtct agcgatcttg tttttcttct cgccccttgc tgttgtgact gccgtcaatc
     4321 cattcttttt atatttagaa aaggggatcg gcatgattgg aagctatttt agtgctccct
     4381 tggtgttagg aagtcctaca gccttacagc tttgcctttg tatggcttgc ttggctatag
     4441 tgtatgatta tcgagggaat cgaggcttac agttggttgc aggtggtttg ttgttgctga
     4501 cgctatttac ggtaaaatgg cccatgacta atgaggtaac gcttgtagat gttgggcaag
     4561 gagacagtat ttttattagg gataagcaaa atcataccat gctgattgat gtcggaggag
     4621 tgcctgctcc tcaggaaaag gagcaatggc ggaggaaata ccaagcctgt aatgcccaca
     4681 aaacactcat tccctatctt agaagccgag gagtagatac gattgatcaa ttggtgctaa
     4741 cccacaccga tactgatcat gtgggggata tggaggctgt tgtgaaggcc tttagagtta
     4801 agcaaatata tgttagtcag gggagtttaa ccaatgctag ctttgtcaag cgattacaag
     4861 gattagctgc caaggttaag gccattagtg ctggtgatca cttgcccatt atgggaagct
     4921 ttttagaggt gctctatcct tgggagatag gagatggtaa aaacaatgat tctttagtcc
     4981 tttatggcag gctattggat aaaagctttt tatttacagg tgatttggag gcagaaggag
     5041 aagaaaggct gattgctcgt tatcctaagc ttaaggctga tgttttaaag gcagctcatc
     5101 atggttctaa gggctcttct ataccagcat ttttagacca tatccagcct cagctaagct
     5161 tgatttcagc aggaaggaac aaccagtatc agcaccctaa ccccgaaacc ttggcacgct
     5221 ttgaagcgag acacattcct tactacagca ccgcaagcaa gggcgctatt cgcttaacag
     5281 gtcaagctca ctggcaatta gaatcctgta gataggctca ttgaaccaga gatatatgca
     5341 agggcctagg tctgggaatg aagtagagaa tgaaaaagat cagctttagc aaggtcatat
     5401 ttagtaagaa aatgctataa taaaaccatg attgcgatag aaaaaataga tgccttaagc
     5461 aaagaaagct taggcttgat tacggtcgta actggtgagg atattgggca atatagccat
     5521 atgaaggcgc tgctactaaa aaaaatagcc tttgatccgg ctgacttgac ttattcttat
     5581 tttgatatgt ctgaggcttt gtatcaaaca gctgagatgg accttgtaag catgcccttt
     5641 tttgctgacc aaaaggtggt tatttttgat catctgctgg acattaccac tagtaaaaaa
     5701 agctacctaa aggaaaaaga gctaaaggca tttgaggact atttggaaaa tcctgtagag
     5761 accacacgtt tggttatctt tgcaccagga aagcttgatg gcaagcgtcg tttggtcaag
     5821 attctcaagc gtgatgccct tatttttgaa gccagtcctt taaaggctgc tgaaaaaagg
     5881 acctattttc aaaaatacag tcaccagctg gacttgagct ttgctagtgg tgcttttgat
     5941 caattgctgt tgaagtcaaa tgatgatttt agtcaaatca tgaagaatat gaccttcttg
     6001 aaggcctata aaaaaagtgg tcctatcaca gtagaggaca ttgctcaagc gattcccaag
     6061 agcttgcagg ataatgtctt tgacttgaca agattggtgt tacaaggaaa gattgatgct
     6121 gctcgggagc tggttcatga tttgcgccta tctggcgagg acgatattaa gcttattgcc
     6181 attatgctgg ggcagtttcg tctgtttttg cagctggcaa ccttggtgcg gtctggaaaa
     6241 acagaacagc agctagtcac tagcctatca gacctgttag gcagacgtgt taatccctat
     6301 caggtgaaat atgcactcaa ggattctaga gccttgtctc tctcttattt gcagctggct
     6361 gtaaagacct taattgaaac agattatcac attaaaacag gtgtttacac aaaggattat
     6421 ctttttgacc ttgctctctt aaagctagta gcgcattctc agggaaatac tgacctctca
     6481 gacctatgag catcaatcaa attagttgaa agcctctatt ttttgagata agatagactt
     6541 atcataaagg aaaagaggaa agagacatga ccattacatt accggatctt ccgtacgcat
     6601 atgatgccct tgagccttat tttgacacag aaacaatgac gcttcatcat gataagcacc
     6661 atgccaccta tgtggctaat accaacactg ctttggaaaa atacccagag ctaggagaaa
     6721 atttagagga attattagca gatgtaagca gcattcctgc tgacattcgt caggctgtga
     6781 ttaataatgg cggtggccat ttgaaccatg cgcttttctg ggagctgctt tctccagaaa
     6841 agcaagaggt ttctgctgat gtcgcagcag ctattgatga cgcttttggt tcctttgctg
     6901 cctttaaaga gcaattcaca gcagcagcta cgggtcgttt tggctcaggt tgggcctggc
     6961 tggttgtgaa taaggctggt cagcttgaaa tcacatcaac tgctaatcag gacacaccaa
     7021 tctcagaggg caagcagcct attttagcac ttgatgtttg ggagcatgct tattacctca
     7081 attaccgcaa tgttcgtcca aattatatca aggccttctt tgaaatcatt aattggaaaa
     7141 aggtctcaga gttttaccaa gctgcaaaat aatagaagtc agttaccaat ctcagaagta
     7201 gattggtttt ttaagtgtgc taataaacta ctagtgttgg tggtaaaagc ctccaagtct
     7261 tttgaaaata ttctctaacg tgatagacaa tacgtgtaac gttcagagtg tatttgatag
     7321 cttagaagct ttataaaaag ccctgccatc tctctagcga atttacccac tagagagatg
     7381 atagagctgt tttttggtta ttggatctac ctcatacctc agctaggggg tcttgctggg
     7441 aaagctttga tgagcttgtt gataatggcg aagtaatttt ttaaaggctt tagccgctgc
     7501 tttcgttaat tgcttggagg atttgccatc tcggctaaaa atagggtgct gttgatcatt
     7561 ttgctgctct aaatctggta ctataaatgg actatcaagg tttatcattg ctgtttcaat
     7621 gaaatcaggc tcaaatagct caatgggttc aatatcaagc aatctatgca gatcattgtt
     7681 ttgattggca tagttaaagg aagacccatt gatgagacca ttttgacttg gctgttgagg
     7741 atctagggca gccaagaaat gaccagcctc tgataaaata aattctgagt gaaaatgaat
     7801 taaaatctta taattggctt gggggaaatt gtctgggtat gtgatttgga gctgattggc
     7861 tgtgtctaaa tgactagcta ccttattgtg gtatctggct gattcattaa gactataatc
     7921 agattcgtct agggtagcta ggtatctagc caaggcatca gcatctgttt ttcctgctct
     7981 cccataattg tttctaaccc attctatttg ctgcactgac aggacatagc gcagctgata
     8041 gagcttgcga ttgaaggtct gataaggaat atgctccaaa tgatcataat aaagctgaat
     8101 taatgatgct aattggtccc aaaaggcatc tgtcgggctt aaggacggac tgaattgctt
     8161 gagtaattgc tttgtttcag cgctttgccc acttaattcc tcgggcattt ttacatagct
     8221 caaaagtaag ctgaggtctc ttttagcttc aagcttatgt tgagcccttg gctgcctttc
     8281 ccacatgcga tgaaaagcag gagacccaat gatctgcagg ctctgataaa gctgctcaaa
     8341 gttatagctt gcttgcttag gcttgagatg gcctaggtag cccttttcaa tggcctcata
     8401 ggaccacccg tcctgtgcta gctttttggc ataatgcagc agatctttcc tgagctgaaa
     8461 ctgatcagat aggcttgagg gctgttgttt tatatgccgc ttttcaaagg aaataaccat
     8521 gtccttgtaa gcttggtggc tctgctcaaa ggccagcctt gcttgctcat gctttgcaaa
     8581 gctaacaaca aacagcacaa ataataaaaa catgagcccg ctgtgaatgt atttcatcat
     8641 taggctttac ttaacaaaca tggcatcacc aaagctaaag aagcggtaat gctcatcaat
     8701 ggcatgctta taggcttcaa ggacaaagtc acgacctgca aaagcagaaa ctagcatgac
     8761 aagcgttgac ttgggcagat ggaagttcgt tgaaaaagca tcaacaacct taaattggta
     8821 gcctggctta ataaaaatat tagtccaacc agaatctgct agaatttgcc cttggaattt
     8881 gctgccaatc gtttctagtg tgcgaataga agtagtacca acagcaataa tgcgtccacc
     8941 agcggcctta accttcctaa gggtttgggc ggcctcttca gatagcaggt agaattcaga
     9001 gtgcatgtca tgctcatcga tattatcgac agaaactggt ctaaaggttc ctaggccaac
     9061 atggagggtc aggtagacga ggtgtactcc tttggcttct attttttgca gaagttcctg
     9121 agtaaagtgt agtccggctg taggagcagc tgctgagcca ttttccttgg cgtaaacggt
     9181 ctggtagcgc tcagcgtctg ctagcttttc atggatatag ggcggaagag gcatttcgcc
     9241 tagagtctct aaaatctcta ggaaaatacc atcgtatgaa aactcaacga ttcgaccgcc
     9301 atgctctagc tcttgaatga cccttgcctt taggcgtcca tcaccaaagc tgatctgtgc
     9361 accggcttta agccgctttg cgggcttggc taaaacctcc cattggtctc cctgaatgtt
     9421 tttaagcagc aaaagctcaa catgcccatg tgtttccatt ttttcaccgt ataagcgggc
     9481 aggaaggacc cgagtattgt tcatgaccag tgcatctcct ggctctagtt gatcaatgat
     9541 atggtcaaag tggctatctg tcatggtgtg ctcttgatgg tcgataatca agagcttcga
     9601 gcgatccctt tgttcaagtg gtgtttgtgc aatcagctcc tctggtagct caaaatcaaa
     9661 atcgttggta ttcatcttaa ctcctttacc cttcttgtga ggctatttac aatcagccta
     9721 tttatcctta gagataaatc ctttctatta tatcacttgt ccctggctac gtcacctgtc
     9781 atggttatga gacacataga gatgattgat ggccttttac tccttattag ctagtgcttc
     9841 ttagctgacg acaggggata tgagattatg gcttgacaat aattggtata taccatataa
     9901 tagaatcaca aaaggtctat accaatcaaa aaggagaatc agatgaaaat tattcgtgta
     9961 caggatcagt tagagggtgg caaggttgct tttagcctat taaaggaaag cttggcaaaa
    10021 ggggctacaa ccttaggatt ggcaacaggc agcacaccga ttacctttta tcaggagctg
    10081 gttaatagtg atttagactg ttcagccttg accagtatca acttagacga atatgtcggg
    10141 ctgccggttg aaaatgatca gagctatgac tattttatgc gtgaccagct gtttaacgct
    10201 aagcccttta aggaaagctt tttaccaaac ggcttagctg atgacttaga ggcagaggtt
    10261 aagcgctatg atcaagttat cgcagagcac cctattgatt ttcagattct tggaattggg
    10321 cgcaatggtc atatcggctt taacgagcca ggaacctctt ttgcagaaaa gacgcatgtg
    10381 gtggatttgc aggcttcgac aattgaggct aatagtcgct tctttgctag tattgatgat
    10441 gtgccaaagc aggctatttc aatgggaatt gcttctatca tggcatcaaa aatgattgtc
    10501 ctattggcct ttggtaagga aaaggctgcc gctattaagg gcatggtatc aggtccagtt
    10561 actgaggctt tgccagcaag tgtattacag cagcacgata atgttgtggt tattattgat
    10621 gaggctgccg cttcagagct ggattagact attgctgatg gctaacagct agtctgctat
    10681 ccgttgtgct cttttgatac agtgtaggta tctggctaaa ggtttcttgc tgactttagc
    10741 aaaaaatctg atcagttatt aaaagaggct ctttggcctc ttttttagaa ttaaggtata
    10801 ttgtgataaa ctaatgctat gcgtttagat aaattattag aagtgacagg ctttggttct
    10861 agaaatcaag tgaaacaact catcaaagga aggtctgtct tgattgatgg gcaaccagct
    10921 agagctggtt gtcagagtgt tgattcaggt cttcaagtga taatggtaaa tggcaggcaa
    10981 ataaaggcat ttgctcatcg ctattacctg cttcataagc cagcaggggt tgtgtcagct
    11041 tgctctgata ggaagcacca aactgtcatt gatttgattc gtaaggagga tagagtggcc
    11101 aatctttacc ctataggccg cttagataga gatacaacag ggcttgtcct cttgacggat
    11161 aatggtccat tagggtttcg tatgcttcac ccgaagcacc atgtgaacaa gacctacctt
    11221 gtgactgtca atggctcttt ggctgctgat gcggtgcctt tctttgaaaa tggtgttacc
    11281 tttcttgatg gtactcgctg caagtctgcc gccttgcgga ttataaaggc tgatcaaatg
    11341 gagtcacaag cagaagtaac actctctgaa ggaaaatacc atcagatcaa gaaaatgttt
    11401 ttaagctatg gcttaaaggt cacacagctc aagcgaattg gttttgcaga aatagcgcta
    11461 ggggatttag ctgagggagc ttatcgtcag ctaacagtaa aagaaaaaaa gctcatcaag
    11521 acctatttaa cataaaatat tgttagattt gaagttgact gacaggttaa gtccagtgtt
    11581 tttcggatat atgctataga gagaacgata acaactggag acccctatgc taactgcctt
    11641 agaccaagat caaagagtca tctcgcttac agatggctct tccccctcac gcaagcaagc
    11701 ctttacctgt cctgcttgtg gagctgctgt acgcttgaaa aaaggaagaa ttatccgacc
    11761 ccactttgcc catattagcc taagtcattg ccaatacctg actgaaaatg aatcacatga
    11821 acatctcagg ctaaaggctg atctgtaccg tagcctatct cgctctgaga cagcagaggt
    11881 tgaggcctac ctgcctgatc taaatcaaat tgcagacctt ctggttaata agcacttagc
    11941 cttagaaatc cagtgtagtc agctaccaat caaaaggctg gagcaacgca gtagggctta
    12001 tcaggctaat ggctatcagg tgcgttggct cttaggaaga aagctttggc tgcaaaagcg
    12061 tctgacaggt ttacaaaggc aatgccttta tttttcttgg cagcttggct ttcatctttg
    12121 ggagctcgat gtggaacacc acctgatacg attgaaa
//
LOCUS       DARYXS010000062        12062 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.063, whole genome shotgun sequence.
ACCESSION   DARYXS010000062 DARYXS010000000
VERSION     DARYXS010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12062
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.063"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            50..4954
                     /locus_tag="TV193_001383"
     CDS             50..4954
                     /locus_tag="TV193_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1513572.1"
                     /translation="MEKKERFSLRKYKSGMVSVLIGILFLTGMGSVVAEEQGVSSAHV
                     SAGQHQESREVLSVSQASEGAAVNAQDIDSQSSKAEEKTEEAMATGLVSSEMEALTES
                     NQSVKQQEESRELPPVNMDTHRWIKTEGAWNRGYKGQGKVIAVIDTGIDASHHAMRIT
                     NPAAAKFTSKADIDQRKKAAGIQYGVWLSDKVVFAHNYVENNDKVKEIKDDPFEGLDD
                     LDFDVIVQQIDIRRNRPQSIEAPQETVIKLDDTSGGTIIDWQDTDDDSKYESHGMHVT
                     GIAAGNGLKAAAAGERFLGIAPEAQVMFMRVFTHDLMGTGDPLFIKAIEDAVALGADV
                     INLSLGSANGSQLNGNRALMAAIEKARQAGVSVVVAAGNERAFGSDHADPLVTNPDYG
                     LVGAPSAGRTPTSVASINNKVIIERLMTVEGLKDRADLNHGKAIYLESVDFKDIKTSL
                     GFDVPYSFVYVKALTKEGYQEREVSGKIVLVQRDPNRKYDDIIAEAKQYGAAGVLIFN
                     NEPGKANRTMRLSSKGMVLPSAFISHEFGMAMAALNGNGTGTLTFDAEVSKAISQKGN
                     EMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGASLLVKQ
                     YLEALQPQLAKDKLADLVKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIETAVTSGL
                     YLTGKDNYGSISLGNVTDQISFEVTIHNLSNQAKSLRYQTELLTDQVDTKEGRFALRS
                     RSLKTYQGEQVDVPAQGHKTITITLDASNFTEELSKQMPNGYYLEGFVRFVDSKDEHK
                     DNINIPFVGFKGAFENLPVVEASIYELKAQGKTGFYFDSSGLKDEIYVGNHFTGLVTV
                     GTDTNVSMTTIADNGLHTLGTFRNKDGKFVLERNAVGYPVLAISPNGDNNQDFAAFKG
                     VFLRKYQGLQARVYKGTDTDRKELLWTSPSALQGDKNFNSDIRFAKSTTLLETGFSGK
                     SLTGADLPDGKYHYVVSYYPDVVGAKRQEMVFEVIVDRQTPELGTASYNPVTHRFRPS
                     QWLDRGQAGVLRDSVFYLETKDDKPYTITINDGLKYVTVSDNKQFVERLADGSFVLPV
                     DQVALGDFYYMVEDFAGNVAIAKLGNHLPEKIGQAELALTLTDINAQHQLSYSDNLNM
                     TAADTGLVTNEAELLIISRNRPQSRLAKLGQTAVISPNDDGNKDFVAFKGLPHQVYQD
                     LKVTVFAQEDTAMTSPIWSSQPGASVANVDSTAWYGTRASGARVMSGHYRYVVSYLDA
                     NGMPQAEAYAVTVSHQKPVITPASFQADGATEVFRPGPSKGQSPIGIVREEVFYLVKK
                     DGRKFDLTVEDQLIRFKDNKVMIAQNADGTYTIPKVEGVAEADYYYLVEDEAGQIAYM
                     SLAALRAVGPDKGVVSVALALDVLENKKEPAFTYLIRDEQGKPIEQLDYFNSSANSLI
                     LPFGRYTVELLAYDNHLFELRSDNLVSFSLDADTRLASVAFEMTRPIVASVWLLFNQV
                     LPEGSRVSLKAANGQLISLAPSLYVPSAYGKTLRQGSYEVLVELPEGYQLIGQGGLEV
                     SHNGVIELTFEVIKAKQPQLEHQAGGLTHYTGSSITSSALTAQAVKKAQVLPSTGEQA
                     AVNLVLLGLLSLGAAGSCQRQKKY"
     gene            5129..6808
                     /locus_tag="TV193_001384"
     CDS             5129..6808
                     /locus_tag="TV193_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513573.1"
                     /translation="MTKKVASLVLIGLDSLILAGFYWIYLPPMNVMSLEFWFFVILAL
                     ILAMVSLFILSLFGLKKTVTSFFTQKSGRKDVTSGLSLKQLTGGIKWLGLALAVIIAG
                     LSLLLAVNTRMFRAKSYAHVIKVKDADFNKDFPDTDLSALALLDRDSAEKIGDTYLGT
                     IDKVSQFGISDEYRQITIGKLPYRVSPLEYKSFWKWLTNRKDGIGYYVKVNQTTGKAE
                     LVKLNQPMKYSHSEFMFRDTMRHLRFQYPMTIFSDPSFEVDDDGNPYYVATTYAPKFG
                     LSSQEPTGVILLDAVSGKSQYYELKDVPKWVDRVYSADNVLERVNDYYTYQKGYWNTV
                     FSQTDVKQTTDSYNYITIGSDIYLYTGITSATADSSNLGFILVNMRTREVTNYKLPSA
                     TEASAMKSAEGEVQEKKYTATAPTLVKLNDKAYYLISLKDGAGLIKSYALVDAEDYQQ
                     VTVNNDIQTLISQFTDKDTSSLSVSDTNDQKVKMITGQVEQLASQIISGTTVYYISSK
                     GQIYKIKASSETSDRLPFLKVGDQFKAQLADDNYLNHMTIESSSADQAITE"
     gene            7343..8364
                     /locus_tag="TV193_001385"
                     /pseudo
     CDS             7343..8364
                     /locus_tag="TV193_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515161.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            8750..9448
                     /locus_tag="TV193_001386"
     CDS             8750..9448
                     /locus_tag="TV193_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEL1513574.1"
                     /translation="MSKRKRKTYQVYEGLRCAMMLCFISGYVNAFTYMTQGRRFAGVQ
                     TGNLLSFAIRLSERQFDQALQFLLPIIVFMIGQAFTYFMHCWANKHGLHWYLLSSFIL
                     TLIALVTAILTPLLSSFFTVSALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYENNKELVHIGRNTLIIILSFALGVVCSTLLSLSYGEYALSPMLIPLCYVNYLL
                     AQEFYHHQVSLKND"
     gene            9666..11669
                     /gene="metG"
                     /locus_tag="TV193_001387"
     CDS             9666..11669
                     /gene="metG"
                     /locus_tag="TV193_001387"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003006062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEL1513575.1"
                     /translation="MTKKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRMLGYD
                     VFYLTGLDEHGQKIQDKAQEAGLSPQAYVDGMAEEVKALWKLLDISYDKFIRTTGDYH
                     EEVVAAVFERLLAQDDIYLGTYSGWYSVSDEEFFTESQLAEVYRDEAGKVIGGVAPSG
                     HEVEWVSEESYFLRLSKYADRLVAFFKAQPDFIQPDGRMNEMLKNFIEPGLEDLAVSR
                     TTFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQKDHANFDKFWSGRVFHMVGKDIL
                     RFHSIYWPILLMMLDLPMPERLIAHGWFVMKDGKMSKSKGNVIYPEMLVERFGLDPLR
                     YYLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGRVPAYVRNV
                     TAFDADLEQVVADHISEYHKQMEAVDYPRALEAVWTIISRTNKYIDETAPWVLAKAAD
                     SKEQLASVMAHLAASLRVVAHLIQPFMMTTSAAIMEQLGLGAKYHLEELDLADLPTGV
                     TVVAKGEPIFPRLDMEAEIDYIKEQMTMSIAKPQEADWDPEKVALKSEKDTITFEAFD
                     AVEIRVAEVKEVSRVEGSEKLLRFRLDAGDGSDRQILSGIAAYYPNEQELVGKKVQIV
                     ANLKPRKMMKKYISQGMLLSAEHDGKLTVLTVDPAVPNGTIIG"
BASE COUNT         3385 a         2375 c         2917 g         3385 t
ORIGIN      
        1 aatcatttgt ttaaaataac cttttttaat aaatctagga ggacatcaag tggagaaaaa
       61 agaacgcttc tcactgagga aatataaatc aggaatggtt tctgtgttga tcggaatcct
      121 ttttctgaca gggatgggat cagttgtggc tgaggagcag ggagttagct cagctcacgt
      181 gtcagcagga caacatcaag aatcaaggga ggtattgtct gtctctcagg ctagtgaggg
      241 agctgctgtt aatgctcagg acatcgacag ccagtcaagt aaagcagagg aaaagacaga
      301 ggaggcaatg gcgactggat tagtttcttc cgaaatggaa gcgctaacgg aatctaacca
      361 atcagtcaag cagcaagaag aatcgcgcga gctacctcca gtaaatatgg atactcaccg
      421 ctggataaaa acagaaggag cttggaatag aggctataag ggtcaaggta aggttattgc
      481 tgttattgat actggtattg acgctagtca ccatgccatg cgcattacaa atccagcagc
      541 tgctaagttt acatcaaagg cagatattga ccagcgcaaa aaagcagcag gcattcagta
      601 cggtgtctgg ctaagcgata aggtagtctt tgcccacaac tatgtggaaa acaatgataa
      661 ggtaaaggag ataaaggacg atccgtttga gggccttgac gacttggatt ttgatgtgat
      721 tgtgcagcag attgatatta ggaggaaccg tccgcagtca atagaggcac ctcaggaaac
      781 ggtcatcaag cttgatgaca catcaggagg aactatcatt gactggcaag atacagatga
      841 tgacagcaaa tatgaatcgc atggcatgca tgtgacaggc attgcagctg gaaatgggct
      901 caaggcggca gcagctggcg aacgcttttt aggcattgct cctgaggctc aggtcatgtt
      961 tatgcgggtt tttacccatg atttgatggg aactggggac cccttattta ttaaagccat
     1021 cgaagatgct gtggcattgg gcgctgatgt gattaattta agtctgggct cggccaatgg
     1081 gtctcaattg aatgggaatc gtgccctgat ggcagctatc gaaaaggcaa ggcaggctgg
     1141 tgtctctgtg gtcgttgctg caggtaatga gcgtgccttt gggtcagatc atgcagaccc
     1201 gttggtgaca aatcctgatt atggcttagt gggggctcca tcagcaggcc ggactcctac
     1261 ctcagttgcg tctattaata acaaagtgat tatagagcgt ctgatgacgg tggagggctt
     1321 gaaagatagg gctgacttaa atcatggaaa ggctatctat ttggaatctg ttgatttcaa
     1381 ggacattaag actagtcttg gctttgatgt accatactca tttgtttatg tcaaagcttt
     1441 gacaaaagaa ggctaccaag aacgcgaagt gagtggcaag attgtcttgg tgcagcgtga
     1501 tcctaatcgg aaatacgacg atattatagc agaggccaag cagtacgggg cagctggggt
     1561 cttgattttt aacaatgagc caggcaaggc taaccgcacc atgcgtctga gttcaaaggg
     1621 gatggtgctg ccatctgcct ttatctctca tgaatttggc atggcaatgg ctgctttaaa
     1681 tggcaatgga acaggcactc tgacctttga tgctgaggtc tctaaggcca ttagccaaaa
     1741 gggaaatgag atgaactatt tctctaactg gggcttgacc tcagatggct atttgaagcc
     1801 tgacatcact gctccaggtg gagatattta ctcgaccttc aacgatgatc actatggcag
     1861 ccagtcagga actagtatgg caaccccaca cattgcaggg gcaagccttt tggtcaagca
     1921 atatctagaa gcgcttcaac cacagcttgc caaggataag ctagcagatc tggtcaaaaa
     1981 tatactgatg agtaatgctc agatccacat caaccctaag accaatacca ccacatcgcc
     2041 acgccagcag ggagcagggc tcttgaatat agagaccgcg gtaaccagtg gtctgtacct
     2101 gacaggtaaa gacaactatg gcagtatttc tcttggaaat gtgactgatc agataagctt
     2161 tgaggtgaca atccataact tgtctaatca ggctaagtcg ctgcgctacc agacagaatt
     2221 gttgactgat caggtggata ctaaggaagg acgttttgcc ttacgttcaa gatctctgaa
     2281 aacctatcag ggagaacagg ttgacgtacc tgctcaagga cacaagacca ttaccattac
     2341 cctagatgcc tcaaacttta cagaggaact ctctaagcaa atgccaaatg gctattatct
     2401 agagggcttt gttcgctttg tggatagcaa ggacgagcac aaggataaca tcaacattcc
     2461 atttgttggc tttaagggag cctttgaaaa cctacctgtt gttgaagcct ctatttatga
     2521 gctaaaggct caaggaaaaa ctggctttta ttttgacagc tcagggctaa aggacgagat
     2581 ttatgtcggc aatcatttta ctgggctggt gactgttggt acagatacca atgtctctat
     2641 gactactatt gctgacaatg gcttgcacac actaggaacc tttcgtaata aagacggtaa
     2701 atttgtgttg gagcgaaatg cagttggcta tcctgtgttg gctatctctc caaatggcga
     2761 caacaatcaa gactttgctg ccttcaaagg ggtgttctta cgtaaatacc aaggcctgca
     2821 agccagggtc tataagggaa cagatacaga ccgtaaggag ttgctctgga cgagcccatc
     2881 agcccttcaa ggggataaaa actttaacag tgatattcgc tttgccaagt caacaacgct
     2941 gttagaaaca ggctttagtg gtaaatcgct gaccggagct gacctaccag atggcaaata
     3001 ccattatgtg gtttcttatt atccagatgt ggtaggagcg aaacgtcaag aaatggtctt
     3061 tgaggtgatt gtggatcgtc aaacgccgga gctaggaaca gcaagctata accctgtgac
     3121 ccatcgcttc agaccgtctc agtggcttga tcgcggtcag gctggtgttc ttcgagatag
     3181 tgttttttac ttggaaacaa aggatgacaa gccttatacg attaccatta atgatggctt
     3241 aaagtatgtg accgtatcag acaataagca gtttgttgag cgcttagcag atggctcttt
     3301 tgtcctgcca gttgatcagg tggcgcttgg tgatttttat tacatggtcg aggattttgc
     3361 aggcaatgtt gccattgcta agctgggaaa tcacttgcca gaaaaaatcg gtcaggctga
     3421 gctggcattg accctaactg atattaatgc tcagcatcag ctgagctaca gtgataacct
     3481 caacatgact gctgcagata caggactggt gacaaatgaa gcagagcttc tcattattag
     3541 ccgcaataga ccacagagtc gtttggctaa attaggtcaa actgctgtca tctcgccgaa
     3601 tgatgatgga aacaaggatt ttgtggcatt caagggcttg ccacatcaag tatatcaaga
     3661 tctaaaggta acggtctttg cccaggagga tacagctatg acaagcccaa tctggtctag
     3721 ccaaccaggt gcaagcgtgg ctaatgttga cagcaccgct tggtatggca caagagcctc
     3781 aggagctagg gtgatgtcag gacattatcg ctatgttgtt tcttatctag acgctaatgg
     3841 tatgcctcaa gcagaggcct atgcggtgac agttagccat caaaagccag tcattacgcc
     3901 agctagcttc caagctgatg gtgctactga ggtctttcgt ccgggaccaa gcaagggaca
     3961 aagtccaata ggtattgtta gagaagaggt cttctacctt gtcaagaaag atggacgcaa
     4021 gtttgatcta actgtcgaag atcagctgat cagattcaag gataataagg tgatgattgc
     4081 tcaaaatgca gacggcacct acaccattcc taaggttgaa ggcgttgcag aagcagatta
     4141 ttattatcta gtggaagacg aggcaggtca gattgcttat atgagcttag ctgctttgcg
     4201 agctgtagga ccagacaagg gagtagtgtc cgttgccttg gcacttgatg tgcttgagaa
     4261 caaaaaagag ccagccttta cttatcttat tcgtgatgag cagggcaagc caatcgagca
     4321 gttggactat ttcaatagct cagctaatag cttgatattg ccatttggac gctacaccgt
     4381 tgagctcttg gcttatgata atcatctgtt tgagctaagg tctgacaact tggttagctt
     4441 tagtctagat gcggatacaa ggcttgcttc agttgccttt gagatgacaa ggcctattgt
     4501 ggcttctgtt tggctcttgt ttaaccaagt cttgccagaa ggcagcaggg tcagcctgaa
     4561 agcagcaaat ggtcagttga tttctctagc tccgtctctc tatgttccaa gtgcctatgg
     4621 taaaacactg cgacaaggaa gctatgaggt cctcgttgag ctaccggagg gctatcagct
     4681 aatcggtcaa ggaggtctag aggtatcaca taatggcgtg attgagctta cctttgaggt
     4741 tatcaaagct aagcagcctc agctagaaca tcaggctgga ggcttgactc attataccgg
     4801 ctcatcaatc actagctctg ccctaacagc acaagcagtt aaaaaagccc aagtcctacc
     4861 atcaacgggt gagcaagcag cggtcaatct agtcctgcta ggcttgctca gtcttggagc
     4921 agcaggctct tgccagcgtc aaaagaagta ctaagcaagc tctatgagcg tagcctgtca
     4981 gctgtattga tcattctagc tgaggtgctc taagagctga taaaaatgtc tggctgagat
     5041 gtcatctttt gaggggaaat gtggtacaat agcggtgaga agatattgaa tacccctgat
     5101 agccttaggg tgtgacgagg agattagtat gacaaaaaaa gttgcttctt tggtgctgat
     5161 tggcttagac agcttgatcc tggctggctt ttactggatt tatttgccgc caatgaacgt
     5221 gatgagctta gaattttggt ttttcgtgat tcttgcgctt atcttggcga tggtgagtct
     5281 ttttatcctg tccttgtttg ggttgaaaaa aacagtgacc agctttttca cgcaaaagtc
     5341 tggccgcaag gacgtgacct caggtctttc actcaagcaa ttaaccggtg gcataaagtg
     5401 gcttggtctt gcccttgctg ttatcattgc tggcttgtcc ttgctgttag ctgttaatac
     5461 tagaatgttt cgtgctaagt cctatgctca tgtgattaag gtaaaggacg ctgattttaa
     5521 caaggatttt ccagacactg atctgtcagc cttggcattg ctggatcgag attcggctga
     5581 aaagattgga gatacttatc ttgggaccat tgataaggta tcgcagtttg gtatttctga
     5641 tgagtaccgt cagattacga tcggcaagct cccttatcgt gtttctccct tggagtacaa
     5701 atccttctgg aaatggctaa ccaatcgtaa ggacggcatt ggctattatg tcaaggtcaa
     5761 tcagacaact ggtaaggcag agctagtcaa gttaaatcag cctatgaagt attctcattc
     5821 ggaatttatg tttagagaca ccatgaggca tttgcgcttc cagtacccga tgaccatttt
     5881 ttcagacccg tcatttgagg ttgatgacga tggtaaccct tactatgtcg caacaaccta
     5941 cgccccaaaa tttggcctgt cctctcagga gccgacgggt gtgatcctgt tagacgcggt
     6001 tagcggcaag tctcaatact atgagctaaa ggacgttcca aaatgggttg atcgtgtcta
     6061 ttctgctgac aatgttttgg agagggttaa tgactattac acctatcaaa agggctattg
     6121 gaacactgtc tttagccaga cagatgtcaa gcaaacaaca gacagctata actacattac
     6181 catcggctca gacatttacc tctatacagg aatcacctca gcaacagctg attcgtcaaa
     6241 tctcggcttt attttggtta acatgcgtac cagagaggtc actaactata agctgccttc
     6301 tgcaacagag gcctctgcca tgaaatcagc cgagggcgaa gttcaagaga agaaatacac
     6361 tgcaactgca ccaaccctag tcaagttaaa tgacaaggct tattacctta tctcattgaa
     6421 ggacggggct ggtctgataa aatcctatgc cttggttgat gcagaggatt atcagcaggt
     6481 aacagtgaat aatgacattc agaccttaat ctcacaattc acagataagg acacaagctc
     6541 gctgtcagtg tcagacacca atgatcagaa ggtcaagatg attactgggc aggtggagca
     6601 attggccagc cagattatct caggaacaac ggtttattac atttcctcca agggtcagat
     6661 ttataaaatc aaggcaagca gtgaaactag tgaccgtctg cctttcctaa aggtcggaga
     6721 ccagtttaag gctcagctgg ctgatgacaa ctacctcaat cacatgacca ttgagagctc
     6781 gtcagcagac caagctataa cagagtaata ttgtttagct ttagcttggc tggcagccac
     6841 tgctttatgc agttgtaaga gtagctggta ctatcagagt agccgcagga aagctcagtc
     6901 acctgtggct cagggactaa cgaggagcag ctgctattgg agatcagttg tagaaagtac
     6961 caaaccaaag ctcgctcctt tcttgaagaa aaccatgtca ttgcaatgtg gcatggtttt
     7021 tgtttgcctt ttaaaatggc taaacagctg attgcaggat agttttgatt aaaaattcta
     7081 ataattaaaa acaataattg tcatataatt aatgttttgt gatattatct tatcatcaaa
     7141 aaatgcttaa aatgccttat ctactggttt ttcagaaaaa ttaaaccaaa tcagatgtga
     7201 catataactg taaaataaca gaaatgtaaa agaaacagtt ttctcttgac taaacagaaa
     7261 atacctttta taataaaagt gtaattatct gtcattgata attaggagac attatgtcca
     7321 ttatatttaa aggggaataa aaatggcaaa aaaagaaatg aagtactatc ttcgtaagtc
     7381 ggctttcgga ctagcttcag tattctgcac cttgttagtt ggtacagctt ctgtatcggc
     7441 acaggtaaca atgagagggc agaagtatgc aactaaagct gaggctacag ctcgtctaac
     7501 tactcttaaa caacagcatc cggaattggc ttcaacaatc gcaggttttg aatcgaaaat
     7561 taacgattca aatttaattc aagttgacga tattaacaaa atcttagctg aggctgaaca
     7621 aactatagcg gttaaggcag aagcagaaag atcaaaacgt gccgaagaag aagcagctaa
     7681 tgaagctctt cgtaaagaga agagtacagt tatctacatt ttcggtagca agcaaggtat
     7741 gactttacca caggagcttc ttgatgttgc taaaatgtca gaactgcaac tggtgagtgg
     7801 agatttactg gttggtcacg ttacacaaat gatggtgaaa ctaaacttac agagggctat
     7861 acagcaccag gtgatggaga tattacttta attggtgatt gggaatttgt tccgtttaat
     7921 gctaatgttc ttgtatctta tgtggataca gaaggtaatg ttttaggtga aactgttgcg
     7981 gtatcacaag gcttgccggg tgaagcgtac gatactacct cacttcgtct tgataagatt
     8041 gaaaaagatg gtaaggtcta caagttcaag aagcttcaag agggctcacc tagcgaaact
     8101 ggtacaaccc tagaaggcga tcttcgtgtg gtttatgtgt atgaagaggt taaacctgag
     8161 cctaaaccag aaccaaaacc tgagcctaag ccagaaccaa aacctgaagc taagaaggaa
     8221 gagaagaaac cagcacctaa gcaagaagct aagaagcttc catcaacagg tgaagcgaca
     8281 catccattct tcacagcggc agctcttgca gtgatggcaa gtgcaggtgt ggttgttgtg
     8341 tcaacaaaac gcaaggaaga ctaatgttgt gctccaatga aaggctgtcc ttagcgctat
     8401 agcttgtgta agctacaagt tgttgaagag gccgactaag aagtcatcag aaatggtggc
     8461 tttttagttt ttttatcagg tttacctgct ggtcctcata gagggtgagt actttttggc
     8521 taatggttag tcttatggtg ctagttgatc ctgcaaagca tcttgataaa agagactgcc
     8581 tatgctatac taaagctgta tttgggggac ttaccgagtc tagctgcaga acttgctttg
     8641 gtgactatct gtgatcaagg gcaattgagc ttagcttatc ctcctaataa tcacatcaaa
     8701 tactgtttgt cagtattttt cttttggaat cacattaagg aaggcaagta tgtcaaagag
     8761 gaaacgaaaa acgtatcagg tatatgaggg cttaaggtgc gccatgatgc tttgctttat
     8821 cagtggttat gtcaatgcct ttacctacat gacgcaaggc aggcgctttg caggggttca
     8881 gacaggcaat ctcttatcct ttgcgattcg tctgtctgag cgccagtttg accaagccct
     8941 gcaattttta ttgcctatca ttgtttttat gattgggcag gcctttacct actttatgca
     9001 ctgctgggcc aataagcatg gtctgcattg gtaccttttg tctagcttta tcttgaccct
     9061 gattgctctt gtgacagcaa tcctcacacc cttattgtcg tcatttttta cggtttcagc
     9121 tctagctttt tttgcttcga ttcaggtaga tacctttaaa accttgcgcg gtgcgagcta
     9181 tgccaatgtg atgatgactg gtaatattaa aaatgctgcc tacctattga caaagggact
     9241 atatgagaac aacaaagagc tagtccatat tggtcgcaat accttgatta ttatcctctc
     9301 ctttgccctt ggagtggtct gttctactct tttatcacta tcctatggtg agtatgcctt
     9361 atctcccatg ctgatcccat tgtgctacgt gaactacctc ttggcacagg aattttacca
     9421 tcatcaggta tcattgaaaa atgattgaag tctactaatt gatatcctcc tcctataatt
     9481 tttgatgact gcttgtttgt cattgtctat tatgggggag gtatcagtta ataggctgag
     9541 tgatcatttt tttatgctaa aattatggta taatgtcagt tgatagctga caggactcag
     9601 cttgggaatg ggtattgccc tagtccctga ttacaaaggt ttcattagcc ttgaaaggac
     9661 gtaagatgac taagaaaaaa ccattttata ttacaacacc gatttactac ccgtcaggga
     9721 agcttcatat tggctctgcc tatactacga ttgcctgtga tgttcttgct cgctataagc
     9781 gtatgttggg ttatgacgtt ttttatttga ctggtcttga tgagcatggt caaaagattc
     9841 aggataaggc acaagaagcc ggcttatccc ctcaagctta tgttgatggc atggctgagg
     9901 aagtcaaggc actatggaag ctccttgata tctcttatga taagtttatc cgcaccactg
     9961 gcgactatca tgaggaggtg gttgctgctg tatttgagag gttgctggcg caggatgata
    10021 tttatttagg gacctattca ggctggtatt ctgtttcaga tgaggaattt tttacagaaa
    10081 gtcagttagc tgaggtttat cgcgatgaag ctggcaaggt cattggtggt gtggcaccat
    10141 cagggcatga ggtcgaatgg gtctctgaag aatcttattt tttgcgcctg agcaagtatg
    10201 cggatagatt ggttgccttc tttaaggctc agcctgattt tattcagccg gacggtcgta
    10261 tgaatgaaat gcttaaaaac ttcatcgagc caggtctgga ggatctagcg gttagccgaa
    10321 caacctttac ctggggggtc cctgtgccgt caaatcctaa acacgttgtt tatgtctgga
    10381 tcgatgctct cttaaactat gcaacagcac taggctacgg tcagaaggat catgctaact
    10441 tcgataagtt ctggagtggt agggttttcc atatggttgg taaggatatt ttgcgtttcc
    10501 acagcattta ttggccaatt ttgttgatga tgcttgattt accaatgcca gagcgtttga
    10561 ttgctcatgg ctggtttgtc atgaaggacg gtaaaatgtc taaatcaaag gggaatgtga
    10621 tctatcctga aatgctggtt gagcgctttg gtcttgatcc tctgcgttat tacctcatgc
    10681 gttccttgcc ggttggctct gatggtacct ttaccccaga ggattatgtt ggtcgtatca
    10741 attatgagct ggctaatgac cttggtaacc ttttgaatcg tacagttgcc atgattaata
    10801 aatactttga cggcagggtt cctgcttatg tcagaaacgt tacagctttt gatgcggatc
    10861 tggagcaggt tgtggctgat catatttccg aataccacaa gcaaatggag gctgttgatt
    10921 acccacgtgc cttggaggcc gtatggacga ttatttcacg cacgaacaaa tacattgatg
    10981 aaactgctcc ttgggtgctt gccaaagcag ctgatagtaa ggagcagcta gccagtgtga
    11041 tggcacattt agctgcaagt ctgcgcgtgg tggctcattt gattcagcca tttatgatga
    11101 caacctcagc tgctattatg gagcagctag gtctcggtgc caaatatcat ctggaagagc
    11161 ttgatttagc agatcttccg acaggtgtga cggttgttgc caaaggagag ccaatcttcc
    11221 ctcgtcttga tatggaagca gagattgact atatcaaaga gcaaatgaca atgagcatag
    11281 ctaagccaca agaagcagac tgggatcctg aaaaggtagc ccttaagtct gaaaaggaca
    11341 cgattacttt tgaggctttt gatgcagttg agattcgtgt ggcagaggtc aaagaggtgt
    11401 cacgagttga aggctctgaa aaactgctgc gctttagatt agatgcaggt gatggctctg
    11461 atcgtcaaat cttatcaggt attgcagcct attacccaaa tgaacaagag ctcgttggca
    11521 agaaggtgca aattgttgcc aacctcaagc cgcgaaaaat gatgaaaaaa tatatcagtc
    11581 agggcatgct tttgtcagca gaacatgatg gcaagctgac agtgctgacg gttgatccgg
    11641 cagtgccaaa tggtacgatt attggctgat tgggctttta gatgacaata tcccgtatgg
    11701 gtcttgctaa tagattgatt agcaggagca tacgggattt ttagtgtctt aaaaagacaa
    11761 gagacctaga cttcttgtgg gagctttgta aactttgaac aagaaagaag cactagtcta
    11821 gcagcctaat aggcaataac agcagtgaaa gctctgagta ttgaaaatac atcatttttg
    11881 tttctttatc tcacgctcta gtcgctccct tcatgggggt gtgaattgat atgtattgat
    11941 cttatttgaa aagcaagttg gcagatgagg gattggtgag catacagaca gggctttcgt
    12001 taaggtgctg ctagctcctt ttatgatttc tttttcataa attaatctat atattgtatc
    12061 aa
//
LOCUS       DARYXS010000063        12006 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.064, whole genome shotgun sequence.
ACCESSION   DARYXS010000063 DARYXS010000000
VERSION     DARYXS010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12006
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.064"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            1..284
                     /locus_tag="TV193_001388"
                     /pseudo
     CDS             1..284
                     /locus_tag="TV193_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            281..766
                     /locus_tag="TV193_001389"
     CDS             281..766
                     /locus_tag="TV193_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL1513576.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKETGKYSVF
                     FQAKDMKVMDKAFKHALAQSEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            763..2234
                     /locus_tag="TV193_001390"
                     /pseudo
     CDS             763..2234
                     /locus_tag="TV193_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001899253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            2188..2544
                     /locus_tag="TV193_001391"
     CDS             2188..2544
                     /locus_tag="TV193_001391"
                     /inference="COORDINATES: protein motif:HMM:NF014581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HEL1513577.1"
                     /translation="MERKKTLKELSETLGKETIDLYNTSETRSNQKSFGLNYQKTGKE
                     LMSQDEITVMDGGKCIFQLRGVRPFLSDKYDITKHKNYKLLEDYDKKNLFDIESYMKR
                     KGKAKLNRETVITRMQ"
     gene            2708..3019
                     /locus_tag="TV193_001392"
     CDS             2708..3019
                     /locus_tag="TV193_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1513578.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGKEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKADKAKDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            3023..3238
                     /locus_tag="TV193_001393"
     CDS             3023..3238
                     /locus_tag="TV193_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1513579.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            3258..4124
                     /locus_tag="TV193_001394"
                     /pseudo
     CDS             3258..4124
                     /locus_tag="TV193_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4144..4407
                     /locus_tag="TV193_001395"
     CDS             4144..4407
                     /locus_tag="TV193_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1513580.1"
                     /translation="MNKRKTVFTAVVMVAGIMAVIDRIRLHNKAAELEERTQDIGRCH
                     NDFCLMQQRYNKNTDEQLAIIQDEIGSVYEHFEEFSKGKEDGR"
     gene            4411..4800
                     /locus_tag="TV193_001396"
     CDS             4411..4800
                     /locus_tag="TV193_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1513581.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLVGIPVYLFMR
                     KVVPNDIAFIFLIVSTLPIFFITLFEKDGLTFEKYFKHIYLHKFYQPAKRVRKEVYLE
                     QEKKNSATKVRRKQKGIKKGEKGLKAK"
     gene            4712..7141
                     /locus_tag="TV193_001397"
     CDS             4712..7141
                     /locus_tag="TV193_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1513582.1"
                     /translation="MNKKRKIQQLKLEENKKALKKERKDLKQSKGKSNKEKSGLLDLI
                     FRKEQKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSIAIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLDIDILSNLKSMGVRAESLTVEERLKILHD
                     ILNPNKTFEFSYKDLKKKESTKTYIVPDEFNFMPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIKAIDQSEAIKMVKRKNTDIDKMRIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHTQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFNGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYERYFENPTYDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            7145..9268
                     /locus_tag="TV193_001398"
     CDS             7145..9268
                     /locus_tag="TV193_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1513583.1"
                     /translation="MDGKLKKDFRERHKASLEREMLKAETSSIPEESKLKHNDDYRGK
                     IVHDKDRFQDKVHEKISKVRSENEQIEGTSKRNAKYRASDKGSVNEAGKADYDTEVKN
                     GKIYDSLGQDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLPQKEKSLENPSKNHKAQK
                     NKYKRKNYSESLYTRKKDDVPKENKPEDKKAGKDVAGEKEHSSLSKDQKKKLKKDMVK
                     VSALSGLAKGSETVRDYLSHGSDENKGVEAGEKTADASSKLIHGIKRYSDKKRAKKGY
                     ELTNKDYKIRKRKSKLEFRDAKEELKKTDEYKRASAYKRFQKKNQVKAAISRENKSRL
                     RDRIKEGLIGTLKSSKDMIIRKAKGLMLIFVGIIILGNFVINFAGTGMTGFMNSTNSV
                     LTTSYLSKPNVLSEINQKFSAMESELQSEVDHVEENYPGYDEYILNNTEYIGHNVHEL
                     LSYITSRCGEVKSVSEVETILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNEYTE
                     SHEEPYEYKKLIVTLHKKEMDSIIRRVFKDYPDNLKHYEALFLAQGNMGEAFRNSDLI
                     SANGGVGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGGNAN
                     DMYRNYTFTSDRSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGYIRVT
                     TLDDWIATFCKHHPVGFGFPPNVNR"
     gene            9281..9520
                     /locus_tag="TV193_001399"
     CDS             9281..9520
                     /locus_tag="TV193_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1513584.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIMI
                     CRKNNITISDLMTKVNREKAELKKERTNENQFEKE"
     gene            9495..11042
                     /locus_tag="TV193_001400"
     CDS             9495..11042
                     /locus_tag="TV193_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1513585.1"
                     /translation="MKTSLKKNNKFWTAALAVIVSISCILGLWTVVYAKEKSSDAPTK
                     NEAVQTEVEVNVKYIFEDEKVFKEEKIKAEKGQLLDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGNDEIIRKVAKTEVKDKETQTEEEKPKQDESTQTEATKTEDKGTQTELSKDDISK
                     MEKEAKELQEKFDKLNGELKDKDKQKEKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKK
                     EIDKLTDKVKELEKKATETKKSSEAINSVTPISPISGIKTSSSISPQTPQTSVSSSGK
                     GSSDTVSSGNATKDTSKTEVKEKEKEVRYSNKLTAKAPANNSSQDSSMEGASSNVNTN
                     KGVASSPSKARGTVTENKDNGNKDYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEIVKEEPVKEEVKPEKKEEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSEAESEEETNDVDE
                     VEAEDEQ"
     gene            11138..11914
                     /locus_tag="TV193_001401"
                     /pseudo
     CDS             11138..11914
                     /locus_tag="TV193_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
BASE COUNT         4518 a         1773 c         2664 g         3051 t
ORIGIN      
        1 gctgcaaaag ggaggatttg attttgataa gaacgcatat attgaatccc ttgtaaatac
       61 ttccgttctt atcttggatg acttgggaat agaaagagat acaagctatg ccaaagagca
      121 ggtatataac attgtcaaca acaggtactt aaagcagaaa ccgactatct tcaccactaa
      181 cctttcctac gacacaatcc aaagaggatt ttagaaagat tattcaaaga gataaattga
      241 atcgaaataa agataggtta ctgaatggag gtgagagaac ttgatcaatg aagaaatagc
      301 aagaaaaacg ctgaatatgg aagtaagagc tgctaaagta acaggaaagt taattctgaa
      361 cttattaaag aaattgatga aagaagcaga aaaacttgga ggacttgaaa agctggttaa
      421 tgctaacgga aatgaagtaa agctaaaaga tatggtaaaa aagggacagc ttgaagaaat
      481 tcctgttgaa gaagcggagc ttaaggaact gaaaaaagaa cttaatcggt atggtgttaa
      541 gttttcagtg atgaaggata aggaaacagg aaaatactct gtattctttc aagccaaaga
      601 tatgaaagtg atggataaag cctttaagca cgcattagca cagtctgaaa agaaaacgga
      661 aaggaaagaa tctattcaca agaatattga gaagtttaag gaaatggcta agaactctgt
      721 ttccaaagat aaaatcaaga ataaacaaaa ggagcagagc ctatgataga taaaatatta
      781 aaggacatca aaggcttatt taaggtgcag gataagacaa agtttgtaaa gcaaaacatt
      841 ccctatcttg catttttcta tttaggaaac atctttgccc atcatgtgag aagctatacc
      901 ggtggtgatg tcatagataa aatctttcaa gggatattgg agatcaacac gatgagtttt
      961 cttccaagta ttcatccggc ggatatttta atgggcatag gaatggctgc tttaattaaa
     1021 tttattgtct ataccaaagg taaaatgcta aaaagtttag acaggggaaa gagtatggct
     1081 cagcaagatg gggaaataag aaagatattg agccatacat ggatgaaaag tttcaaaaca
     1141 atatcttgct tacccagaca gaacgcctaa ctatgaatgg tagaccggct aatccaaagt
     1201 atgctcgtaa caagaatgta cttgtaatcg gtggatcagg aagtggtaag acaagatttt
     1261 atgtaaaacc gaaccttatg cagatgcaca gtagctattg cgtaaccgat ccgaaaggaa
     1321 cgatagtcat tgaatgtggc aagatgcttg aagacaatgg atatgagata aaaattctaa
     1381 ataccataaa cttcaaaaag agcatgaaat acaatccctt tgcctatatc cattctgaga
     1441 aagatatact caaattagtg cagacaatca ttgcaaatac aaaaggtgag ggagaaaaag
     1501 cgggtgaaga tttttgggtc aaagcggaaa aactctacta cacagcactt atcggatata
     1561 tcttctatga agctccaaga gaagaaaaga actttgcaac gctccttgat atgatagacg
     1621 cttcagaagt aagagaagat gatgaaacct atatgaatcc aatagacaga ctctttgaag
     1681 cacttgagaa aaaggagcct acgcactttg cggtcaagca atataaaaaa tataaattgg
     1741 ctgcgggaaa gacagcaaaa tctattctta tatcttgtgg tgcaaggctt gctccatttg
     1801 atattcagga acttagagat ttgatgagtg aagacgaact tgagcttgat acattgggag
     1861 atagaaagac agcactcttt gttattatct ctgatacaga tgataccttt aactttgtag
     1921 tgtctattat gtattcacag ttatttaatc tactttgcga taaggcggat gatgtatatg
     1981 gtggcagact tcctgttcat gtaagatgct tacttgatga gtttgcaaat atcggcttaa
     2041 ttccaaagtt tgagaagctc atagccacaa ttagaagtag agaaatttca gcgagtatta
     2101 tcttacaggc acaatctcag ctaaaggcaa tatataagga taatgctgat accattgtgg
     2161 gtaactgtga tagtacctta ttcttaggtg gaaaggaaaa aaacactaaa agagctgtcc
     2221 gaaacgcttg gtaaagaaac tatcgacctt tacaacacat cggaaacaag gtcaaatcaa
     2281 aagagctttg gacttaacta tcaaaaaaca ggcaaagagc tgatgagtca ggatgagatt
     2341 acggtcatgg atggtggaaa atgtatcttt cagcttagag gtgtcagacc ttttctttca
     2401 gataagtacg atattacaaa gcacaagaac tataagctgc ttgaggacta tgataagaaa
     2461 aatttatttg atatagaaag ctacatgaaa cggaaaggaa aagcaaaact gaatagggaa
     2521 acagttatta caagaatgca gtaagtctac aaaatagatt tgctgctttt ttatgcaaaa
     2581 gtaaggaggc aagatgataa ggatcagaag tcccactgag taaaaaacta aatagtatga
     2641 gtatagcgat tggaaaagta atacttccgg tcgctttttt tattgaaatg aaaaggagaa
     2701 atttttaatg aagcaagaaa tgattaacat caacgccaac ttagtggcag aacctacttt
     2761 ctcaagtttt gaaaaagagg gtaaagaagt agaagttgta aattttacgc ttgtaaagaa
     2821 gtacggtaaa ggcaaggagt acatcaattg tgcagcctat ggagaaaaag cggataaagc
     2881 aaaggacttt gaaaagggcg atttgattca tgtattcggc tactttaaga agcgtgaaaa
     2941 agagggaaag acttacaaaa attttgtagt gaagtcatac aacaagattg aaaagaaaga
     3001 agaaaatgag gaggaataaa ttatggaatt tttcgcacag gcagtaaatg tattaaagat
     3061 tttggttatg gcagtaggag caggacttgg agcatggggt gtcattaacc tgatggaagg
     3121 ttatggtaac gataatccgg gagccaaaag tcaagggatc aagcaattga tggcgggagg
     3181 aggtattgtc cttatcggac ttaagctgat tccacttctt gcaaatgtac tcagataaga
     3241 agaaaaggag agcttagatg tttgggatat tcgacaaaat agaagaattc tttaaggagc
     3301 ttctactggg cggtatccaa gcaaacttag agtccatgtt tcttgacatc aacgacaagg
     3361 ttggtgcagt tgcaacagat gtaggaaaaa ctcctatggg gtggaatgga gatgtattta
     3421 cctttattaa aagcattaac gattcggtca ttattcccat agcgggacta attatcacag
     3481 cagtcctttg tatcgagctt atcaatatgg ttatacagaa aaataaccta catgataata
     3541 cggatacatt tgaatttttc aagtacatca tcaagatgtg aattgctgta tggttggtat
     3601 ctcacgcttt tgaattttca atggcggtct ttgatgtagc acagcatatg gtaaataagg
     3661 cggcaggggt gataaacacc tctgccaccg tttccggaga tcagatagtg gcgatgatgg
     3721 ataccctaaa agaaaaggga cttggagagc ttatcatgat tctctttgaa acctcgctca
     3781 ttaaagttgc catacaggca atttccatag tgattatgct tgtggtttac ggaaggatgt
     3841 ttgagattta tgtttattca tcggtttcag ccattccatt tgccacgatg ggaaacaaag
     3901 aatgggggca aattggcaca aattacatca aaggattatt tgcacttgga ctacaaggac
     3961 tctttttaat ggtttgtctt ggaatttacg cagtattagt taagacgatt gaaataacag
     4021 atatacacac aagtaccatg acgatacttg gttatgcggt tttgctgggg ttaatgatgc
     4081 taaagagcgg aacactggcc aaaagcgtat taaatgcaca ctaaaaaaga aaggaaagat
     4141 agtatgaata aaagaaaaac agtatttaca gcagtagtaa tggtcgcagg cattatggcg
     4201 gtaattgata gaatcaggct tcataacaaa gctgccgaat tagaagaaag aacacaggac
     4261 atcggtcgct gccataatga tttttgctta atgcagcaaa gatataacaa gaatacagat
     4321 gaacagcttg caattattca ggatgaaatc ggctctgtat atgaacactt tgaggagttt
     4381 tcaaagggta aagaagatgg gaggtaagct atggcgtatg taccaatacc caaggactta
     4441 aagaaggtca agacaaaggt agcctttaac cttacaaaaa gacagctcat aggatttacc
     4501 attgcaggac ttgttggaat acctgtctat ttatttatga gaaaggtagt accaaacgat
     4561 atagctttca tattccttat cgtgtccaca cttccaatct tttttatcac actttttgaa
     4621 aaggacggac tgacctttga gaaatatttt aagcatatct accttcataa gttttatcag
     4681 ccggcaaaga gagtgagaaa ggaggtttac cttgaacaag aaaagaaaaa ttcagcaact
     4741 aaagttagaa gaaaacaaaa aggcattaaa aaaggagaga aaggacttaa agcaaagtaa
     4801 gggaaagtct aacaaagaaa agagcggact acttgatctt atctttagaa aagagcaaaa
     4861 acgctatacg gtagaagata ccattcccta tcttagactc ttaaaaagcg ggatatgcca
     4921 gctcgatgaa aagcacttca gtaaaagcat agcctttcag gacattaact atcagcttgc
     4981 tttagatgaa gatagggatt tgatttttaa tcagtttgca aactttctaa attcctttga
     5041 tccaagcata gcgattgagt tttcctacat caatcagctt ggacgaaacg aagaaatgaa
     5101 atcggcaatt cagataccgg ataaagggga cggatttgac gatatacgac ttgagtttag
     5161 agagatgcta aaaagtcaga ttgtaaaagg aaataacgga ctgaaaaaat caaagtatgt
     5221 aacctttaca gtagaggcag acaatttaga acaggctaca tcaaaacttg aaagattgga
     5281 tatagatata ttatctaatc tcaaaagcat gggggtaaga gctgaaagtc ttacagtaga
     5341 ggaaaggcta aagattcttc acgatatatt aaatccgaat aagacctttg agttttccta
     5401 caaagacctg aagaaaaagg aaagtaccaa aacatatatc gtgcctgatg aatttaactt
     5461 tatgccaagc aggtatttca agtttgggaa gtttatcgga gcaacaagtc attttcaaat
     5521 ccttgcaagt gagctttcag accgtatgtt atcggagttt ttggatattg atgataacat
     5581 caatatatct tttcatatta aggcgattga ccagtcagaa gccatcaaga tggtaaaacg
     5641 aaaaaacacc gatattgata agatgcgaat tgaggaaaac aagaaagctg taaggtcagg
     5701 ctatgacatg gacattcttc caagtgattt aattacttac ggagaagatg taaaaagtct
     5761 tttaaaagat ttacagacaa gagatgagcg tatgtttgtt gtaagtattg tctttatgaa
     5821 ttttgcaagg acagtgcaaa agctcgataa caccatagct cagataagct ccattgcaaa
     5881 caagcataac tgtaaattga aaagacttga ccatacgcag gaacaaggct tagtgagcgt
     5941 gctgcctctt ggggtaaaca agattgaaat agatagaggg ctaacctcat catcaacagc
     6001 agtctttatg ccttttacaa cagaggagct ttttatcaat tcaagtaata gcctatacta
     6061 tggactaaac gctttaagcc ataacctgat tatggcggat cgaaagaaat taaagaaccc
     6121 aaacggtcta atcttaggaa ctccgggtag tggtaagtcc tttagtgcca aaagagagat
     6181 ggcaaatgcg attttagtaa cggacgatga tgtgattatc tgtgatccgg agggagagta
     6241 tggaaacctt gtaagacagt ttaatggaga agtcattaag gtcagcagta agtcaaaaga
     6301 ttacctgaat ccacttgata taaatatgaa ctacggtgat ggggacgcac ctcttaaaga
     6361 caaggcaaac ttcattatgt ctatgcttga gcttgtagtt ggtggtagtg gacttacagc
     6421 ggaagaaaag tccgttatag atagatgctt acctaagatt tacgaaaggt actttgaaaa
     6481 tccgacttat gacaatatgc ctatacttca agacctatac gatatgttaa aagggcagga
     6541 agaaaaggta gggaaaaagc tggcaacaga gatggaaatt tatgtttcag gttctcttaa
     6601 tgtctttaat cacaggtcaa atgtggactt aaataagaag ctactttgtt ttgatattaa
     6661 ggagcttgga agtcaattaa agaaaatagg tatgcttgtt atacaggatc aggtgtggaa
     6721 taaggtatcg caaaacagag gaaacaaggc tacaaggtac tatatagatg agtttcactt
     6781 gctgttaaaa gatgagcaga cagcttcata ttcggtagag atttggaagc gttttagaaa
     6841 atggggagga atcccgactg gtatcacgca aaatgtcaaa gacctactta tgagtaagga
     6901 aattgaaaat atctttgata atacggactt tgtcttaatg ttaaatcagg cttcgggaga
     6961 tagggaaata cttgcaagga aacttaaaat ctcacttccg cagcttagat atgttacgaa
     7021 ctccaatgag ggcgagggac tacttttctt tggaaatacc attgtgcctt tccttgataa
     7081 gtttccgaaa gatacaattc tttatcagaa gatgactacc aagcctgaag aagtgaggta
     7141 gcttatggat gggaagctga aaaaagattt tagagaaagg cataaggcaa gccttgaaag
     7201 ggagatgctt aaagctgaaa caagctctat acctgaagaa agtaagctaa agcataacga
     7261 tgattacaga ggaaaaattg tccatgacaa agatagattt caggacaagg ttcatgagaa
     7321 gataagcaag gtaagatctg aaaatgagca gatagagggg acttctaaaa gaaatgcaaa
     7381 gtatagggct tctgataagg gaagtgtaaa tgaagcagga aaggctgact atgatactga
     7441 ggtaaagaac gggaaaatct atgattcttt aggacaagac cttgataatg atggaatcat
     7501 agacagatac gataatgatt ttagggacag cgactacttt gaatcaacct atgatgtaga
     7561 ggataatcta cctcaaaaag aaaaatcatt agaaaatccc tctaaaaatc ataaggctca
     7621 aaagaataag tataaaagga aaaactattc cgaaagcctc tatacaagaa aaaaggacga
     7681 tgtaccaaaa gagaataagc ctgaagataa aaaggcaggg aaagatgttg cgggcgaaaa
     7741 agaacatagc agtctttcaa aagaccaaaa gaaaaagctg aagaaagata tggtaaaagt
     7801 atctgccctg tcaggacttg ccaaaggaag tgaaaccgta agagattacc tttctcatgg
     7861 aagtgatgaa aataaaggcg tagaagcggg agaaaaaaca gccgatgcaa gttcaaaact
     7921 cattcatggt ataaagagat actcagataa gaaaagagct aaaaaaggat atgagcttac
     7981 aaataaggac tataaaatca gaaagcgtaa atccaagtta gagtttcgtg atgccaaaga
     8041 ggaactgaaa aagacagatg agtataaaag agcaagtgcc tataaaagat ttcaaaagaa
     8101 aaatcaggta aaggcagcga tttctcgtga gaataagtca agactcagag atcggattaa
     8161 agagggactt atcggaacac tgaaaagctc aaaggatatg attatccgaa aagccaaagg
     8221 actaatgctt atcttcgtag gtatcatcat cttaggaaat tttgtgatta actttgcagg
     8281 aacaggcatg acaggcttta tgaactctac aaactctgtt cttacaacaa gctatttatc
     8341 aaagccaaat gttctaagtg aaatcaatca gaagttttct gctatggaga gtgagcttca
     8401 aagtgaagtg gatcatgtag aagagaatta tcccggatat gatgagtata tcttaaacaa
     8461 cacagagtat atcggtcata atgtccatga gcttttatcc tacattacat caaggtgcgg
     8521 agaggtaaag agtgtatcgg aagtagaaac catattaaaa gaattgtttg agtccatgta
     8581 tgaccttgaa tacagggaag aaattgaaat cagatacagg acagttacag aaacctatac
     8641 cgatgaagat ggcaatgaat ataccgaaag ccatgaagag ccttatgaat ataagaagct
     8701 cattgtaacg cttcataaaa aagagatgga cagcattatc cgaagggtct ttaaagacta
     8761 tcccgataat ttaaagcact atgaagcctt attccttgct caaggaaata tgggagaagc
     8821 ctttagaaat tctgacctta tcagtgctaa tggcggtgta ggtggtggga aagagtatga
     8881 ggcatcttcg gaagtacaaa agaagattgt taatgctgca tatatcactc catctccggg
     8941 tgcaggctgg tgtgccatgt gggtatcgca agtttaccaa aatgcgggac ttggatatat
     9001 cggaggaaat gctaatgata tgtatcgaaa ctataccttt acatccgata ggtcaaagct
     9061 caaggtagga atgcttgtag cggtagaaag cagcagtagc ggaagcacag caggacttac
     9121 ctatggtcat gtcggaatct atatcggaga cggcaaggtt attgataata tcggttatat
     9181 aagagtaact actttagatg attggattgc gactttttgt aaacaccatc cggtaggctt
     9241 tggttttcca ccaaatgtaa acagataagg agggaacaat atgaaaaaag aactgacagc
     9301 agtaaaaaac agaataaaaa agttaaagga taaaaaggct ctgattgatg aagaattgga
     9361 gcctttattt attcgtgaag aagaacttga aaatgaagaa atcatcatga tttgcagaaa
     9421 gaacaacatc acaatttctg atttaatgac aaaggtaaac agagaaaaag cagaactgaa
     9481 aaaggagagg acaaatgaaa accagtttga aaaagaataa taagttttgg acagcagcac
     9541 ttgcagtaat tgtaagtatt agctgcattt taggactttg gacggttgtt tacgccaagg
     9601 agaaaagctc tgacgctcct acaaaaaacg aagctgtcca aacggaagtt gaagtaaatg
     9661 taaagtatat ctttgaagat gaaaaggtat ttaaggaaga aaagattaag gcagagaaag
     9721 gacagcttct tgatagtggc gatcttccaa tgctccctga tgatatgaaa tttattgatg
     9781 aattcctgtt ttatgaagta aagggagatg gaaatgatga aattatccgt aaggtagcaa
     9841 agactgaggt taaggataag gaaacgcaaa cggaagaaga aaaaccaaag caggacgaaa
     9901 gcacgcaaac agaagctaca aaaacggagg ataaaggcac acagacagag ctttctaaag
     9961 acgatatttc taagatggaa aaagaggcta aagagcttca agaaaaattt gataagttaa
    10021 atggtgagct taaagacaag gataagcaga aagaaaaaat caaagacctt gaagatgaaa
    10081 ttgacagcct gaaagagaaa atgaagaaag ataaaggaaa taaggactta tcagaagata
    10141 tgaaaaagga aatagataag ctgactgata aggtgaaaga gcttgagaaa aaggcaactg
    10201 aaacaaagaa atcttctgaa gcaataaatt ctgttacacc gattagtcct atttccggaa
    10261 ttaagacaag ctcaagcatt tctccccaaa caccacagac ttctgtaagt agttccggta
    10321 aaggctcatc tgatacggtg agttcaggga atgctacaaa ggatacaagc aaaacagaag
    10381 taaaggagaa agaaaaggaa gttcgctatt ctaataaatt gacagcaaaa gcacctgcta
    10441 ataacagcag tcaagattcg tcaatggagg gggcaagtag taatgtaaat accaataagg
    10501 gagtagcttc atctccgtca aaggcaagag gaactgttac agaaaataaa gataatggaa
    10561 ataaagatta tccgattcat catggggata gcagcgataa taaagaaacg gatcaatatt
    10621 ccgctgatgc aagacagttt attacctttc aaactaaaaa cggtaagacc tttcatctca
    10681 tcatcaacca cgatgaggat agtgagaatg tcatgcttct tacagaagta tccgaagatg
    10741 atttgcttaa catggtagag aaaaaagaag ctccaaagca ggagattgta aaagaagaac
    10801 ctgttaagga agaagtaaag cctgagaaaa aagaagaaaa gagtaattta ggaacatata
    10861 ttattctgct tcttgttgta ggcggagcat tgggagcagg atactacttt aaggttgtaa
    10921 aaaagaaaga agataaggag cttgaagcat tagaggaaga agatgatgat ttcttttctg
    10981 aagctgaaag cgaggaagaa acaaatgatg tagatgaagt agaagcggaa gatgagcagt
    11041 aatgctgcac caaaaaaata cagtatttgg tgcaaatgca gggcgggaga ataaaatctt
    11101 tcgccctttt atattgaaaa caggaggcag tacagaaatg aagttagtca ttgcagaaaa
    11161 accaagtgta gcattaagta ttgcaaaagt acttggagca aataaaaaga aagacggata
    11221 ttatgaggga aatggataca aagtatcttg gtgtgttgga cacttaattc aaatggcaaa
    11281 tccggatgtt tatgatgaaa agtatgccaa gtggaatatg gttgatttac cgattatccc
    11341 caaggactat aagtatgaag tggcaaagtc aaccaagaaa caatttaaca tccttaaaaa
    11401 gttgatgaac gacaaagaaa ttgatacggt tatcaatgcg tgcgatgcag gtagagaagg
    11461 ggagagcatt tttagacttg tatataatca agtgaattgt aaaaagaaga tgaaacacct
    11521 ttggatttca tctatggaag atactgccat taaagatggc tttgatcatc taaaagacgg
    11581 aaaagattac gataatctct ttgagtcggc acaggcaaga gctatcgctg actggcttgt
    11641 cggaatgaat atcagcaggc tctattcttg tctgtataag caaaattaca gtgttggcag
    11701 agtacaaaca ccgactcttg ctatgatcgt aaaaagagat gatgagatag caaactttaa
    11761 gaaagaaaaa tattatacgg tagagctttc tacaaatagc tttacacttt caacagatag
    11821 aattgatgat gaaatagcag cagagcagct cttaacttta gtgggcaata agattgaaat
    11881 aactgatgtc attcaaaaag aaaagattac taaatgtact gcccccaaaa agttggacga
    11941 ataattattg aaaggattta gttctgtatt gcacagggct aagtcctttt agctttgctt
    12001 taatgc
//
LOCUS       DARYXS010000064        11945 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.065, whole genome shotgun sequence.
ACCESSION   DARYXS010000064 DARYXS010000000
VERSION     DARYXS010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11945
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.065"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            37..321
                     /locus_tag="TV193_001402"
     CDS             37..321
                     /locus_tag="TV193_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1513586.1"
                     /translation="MSEEATLVVQLPKVLEKQLRAHYDEMVSTAIERALEDKELYKPM
                     VRMAALSRWLDVSTTTLQKWTREGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            330..815
                     /locus_tag="TV193_001403"
                     /pseudo
     CDS             330..815
                     /locus_tag="TV193_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
     gene            867..1154
                     /locus_tag="TV193_001404"
     CDS             867..1154
                     /locus_tag="TV193_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1513587.1"
                     /translation="METLWHRELTQQEKVLLEGFAVNDSLLQLAIQKTEELEPKKQNM
                     SYVKGILMNWEARGFITVDQVIASEEDYRPLEIANVEVSEDFLAAMDIWKD"
     gene            1169..1459
                     /locus_tag="TV193_001405"
     CDS             1169..1459
                     /locus_tag="TV193_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513588.1"
                     /translation="MTVYYQLENMLVAGFKSQDEYDRYQALKRDYEGESEDYSFSIRE
                     ITNQLEIICQTSENDFPNLSEALMIDYLELVGELKRYDTNQADRYLGMVRHV"
     gene            1452..1814
                     /locus_tag="TV193_001406"
     CDS             1452..1814
                     /locus_tag="TV193_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1513589.1"
                     /translation="MSERIRTILKKFYVTELQNEVLNQLVNDTGLQTFSNYARRMLFK
                     ETSLFMRFDESQFDELIYSLRRIQNNLRQLSKIAEQSQDSQAYRAMDYSRRLVSHYEK
                     QLTRYHKKKKRKLLSKGA"
     gene            1814..2170
                     /locus_tag="TV193_001407"
     CDS             1814..2170
                     /locus_tag="TV193_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1513590.1"
                     /translation="MDKRRIRNVIKQVFLSEEENQKLLEKMKQDGFTNFSLFARKQLL
                     KPDFETWLVSFPEYQPLTGRLLSVGRTINGIAKSATQFGKISQHDLMELGQLMEELVE
                     LVEKQVKEDKQRIAKK"
     gene            2514..4058
                     /locus_tag="TV193_001408"
     CDS             2514..4058
                     /locus_tag="TV193_001408"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEL1513591.1"
                     /translation="MSEQAQRQELHRKIWAIADDVRGAVDGWDFKQYILGILFYRFIS
                     ENFKTYIEGGEDFNYEEIPDEVITPEVKDDAIKTKGYFIMPAQLFSNVVKTARSNDNL
                     NTELKDIFDAIEASAMGYASENDIKGLFDDVDTRSNKLGSTVPERNERLALILEGIAS
                     LDFGSFEDNHIDLFGDAYEFLISNYASNAGKSGGEFFTPQSVSRLLARIVMLGKDEKN
                     KINKIYDPACGSGSLLLQAKKQFTEHIIEDGFYGQEINMTTYNLARMNMFLHNINYDK
                     FSIERGNTLLDPKHGNDKPFDAIVSNPPYSIKWVGSDDPTLINDDRFAPAGILAPKSK
                     ADFAFIMHSLSYLSNKGRAAIVTFPGIFYRGGAEQKIRQYLVDGNFVETVIQLPDNLL
                     FGTSIATCILILAKNKPTTDVLFIDASQQFKKETNNNVLTEENIEKILKSVEHKNNEE
                     YFAQLISQEKIVEADYNLSVSTYVEKEDTREKINIDVLNKEIAETVKNIDRLRAEIDK
                     IVEELS"
     gene            4060..5946
                     /locus_tag="TV193_001409"
     CDS             4060..5946
                     /locus_tag="TV193_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1513592.1"
                     /translation="MTYIDEMIKELCPDGVEWKELGEVVDYEQPTKYIVKSKEYSDDY
                     SIPVLTAGQTFILGYTNEVTGIYPASKEHPVIIFDDFTTARKWVDFEFKVKSSAMKLL
                     SIKSDRQDDVSIRYVWHYLGTIKYTPEQHARQWIGTFSKFKIPLPPLEIQGEIVKILD
                     KFTEHVTELTAELTAELTFRQKQYSYFRDKLLSFDDESMGGANDKVYTVQWKTLGEVV
                     NFRRGSFPQPYTDMSFYGGEDAQPFVQVVDVADEGFRLNTKTKKTISQKAIPKSVFVP
                     KGTVIVTLQGTLGRVAVTQYDAYVDRTLAIFDGYKQEVDKRYFAHQLKFIFDREKEFA
                     RGSTLKTITKQEFSNFKIPVPPLDIQRRIVQVLDNFDTVCNDLNIGLPKEIELHQKQY
                     AYFRDKLLTFTAEGVYTDSTVQYSTVQYRQDLIRLLTWVFGPIKVELGAVCDVVRGNG
                     LQKKDFVNEGYPVIHYGQIYTFYGLSARVTKSFVSPEVGQKLKKAKTGDVIVATTSEN
                     IEDVGKALVWEGAEDVCIGGHSCVLHTEQNSKYLLYYFQTTVFQKQKEKLVIGTKVIE
                     LYPKNLEKAIIILPPVYEQGRIVSILDKFDTLTSDLTQGLPKEIEQRQKQYEYWRDLL
                     LNFP"
     gene            5961..7169
                     /locus_tag="TV193_001410"
     CDS             5961..7169
                     /locus_tag="TV193_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1513593.1"
                     /translation="MGNDIKFENLEQISDNIISSNKKVHLLYAYNATGKTRLSMELKN
                     KVNETDSDGNSIKHILYFNSYTEDLFTWDNDLENDEDRYLIYDKRTYFGNFLEEQQLF
                     ERAVDNFQKYVGRSIDIEFQDVIETVKDEFGNVQKDNRGEALTISNKKSIRFKVDGHT
                     IKVSRGEERIFVWSVFLTLLEIIIEDLTESADTSEFSKMNYIYIDDPISSLDDTNIIN
                     AAIYLSDVIGSAENTDLKFVVSTHQALFYNVLYNEIRFDRRIKKKVFYVMKATDEIED
                     EKQFKYLLTDVEGDSPFGYHLRVREELRKAIQDEQVEKFHFALFRNLVEKTATFLGYG
                     RWENILLGLDVAGHVITSENIKLYTQLIDLYTHNRHADLEYRELPPQEKNTLINLFNS
                     FDSIYRFKED"
     gene            7172..10267
                     /locus_tag="TV193_001411"
     CDS             7172..10267
                     /locus_tag="TV193_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEL1513594.1"
                     /translation="MTEIIQTDTILEAKNFIVLEKYTKLEKPSTYQTEADLERELVSD
                     LRQQGYEYLNNLTTPEALLDNLKTQMEALNGVVFSEAEWLRFLEEYLNKPSDGLIDRT
                     RKLHDNHIYDFIFDDGHIQNIYLWDKKNISRNKLQVINQMSQVGTSSNRYDVTILVNG
                     LPLVQIELKKRGVAIREAFNQVHRYSKESFNEENSLFKYLQIFVISNGTDTRYFANTT
                     KREKNSFDFTMNWALKNNEPIKDLKDFTATFFSQQTLLNILINYSVFDTSDTLLIMRP
                     YQIAATERIIWKIRSAIDSKIKSGPETGGYIWHTTGSGKTLTSFKAARLATEMDKVDK
                     VFFVVDRKDLDYQTMKEYQRFSPDSVNGSNSTAGLKRNIEKDDNKIVVTTIQKLNNFM
                     SSEAQHEIYNKQVVFIFDECHCSQFGEAQKRLKQKFKKYCQFGFTGTPIKVENALGSE
                     TTASVFGRELHAYVITDAIRDQKVLKFKVDYNDVRPQFKSLETEQDLGKLSAAENKKA
                     LLHPTRITEISAYILEHFNQKTHRQNGKGFNAMFAVSSVEAAKAYYQELQDQQAGKAK
                     PLKIATIFSYAANEEQAAIGEIDDETFSPADLSDISSKEFLSGAISDYNRLFQTNFSI
                     NGNEFQNYYRDLAKRVKSGEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLIQAFS
                     RTNRIYNATKTFGNIVTFRDLEKATTDAIKLFGKTETADILLERSYEDYMNGYIEAGQ
                     EQKGYLEVVKELQERFPDPTTIIKESDKKEFVTLFGQFLRLDNILQNYDDFMSLQALQ
                     ELDVTDIEALADFKGRFHLDDEAVAVLSQLDIPSVREIQDYRSAYNDIKSWYDNERRN
                     QQNNDSEIDWDAVVFEVELLKSQEINLDYILELIFETNQKVSDKDQLIEEITRTIRAS
                     LGQRAKESLIVDFINASDLDSFSEKSDILEQFYTFARQKQKEAVANLIETEGLNVESA
                     SRYIQMSLKREYASENGNALNEALPKMSPLNPQYRTKKQMVFEKIVDLVEIFKGIGGE
                     I"
     gene            10435..11886
                     /locus_tag="TV193_001412"
     CDS             10435..11886
                     /locus_tag="TV193_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1513595.1"
                     /translation="MENKKDLIQTLAYYQFSLENQYLDRKSARKKPQELLKHLIAFAN
                     ADGGQLVIGIEDEKQDNIITGFKDGRAYPIDDFKKIDHEMRETPLDLSLEEIPVLNHK
                     GEDDLILVISVELSSNRVIAAPNDEVYLRQGDESVKLSYEQRTQLSYDKGQRFFEDEV
                     VPDATLEDIDDGLVQDFKNRFDISERSMEEVLKARRFLVNGKLTKAAILLFAKYPSAF
                     FPQARVRFQRFDGTDMGTGSSFNVIKEVTFDDALPTLIIKVRDFIRTQLREFQYLDDN
                     GQFQILPEYPEFAWFEGVVNAVTHRDYSVYGDHIRVLMFDDRLEIHSPGKLPNIVTVD
                     NIKHECFSRNPRIARTLTEFGWVREMNEGVKRIYSEMESAFLHEPKYLEPGNKVVLTL
                     ENNIVSRHLRTRDSLEKQFSDFGNLTADEQAIVHYMYNSGDKMTTAKAIELTGRSRSF
                     VVKMLHHLRDLEIITWFGSSKNDRNQYYLLVDK"
BASE COUNT         3863 a         1928 c         2651 g         3503 t
ORIGIN      
        1 gtttatttaa ttgagaaatg gaaacgaggt aatgatatgt ctgaagaagc gactttagtt
       61 gttcaacttc ccaaagtttt ggaaaaacaa ttaagggcac attatgatga aatggtttct
      121 acagctattg aaagagcgct agaggataaa gaattatata aacctatggt tcggatggca
      181 gccctttcta gatggcttga tgtgtcaacg acaacacttc aaaagtggac gcgagaagga
      241 atgcctacaa tggttattga tggtgtgact ctgtacgata aacgtgcggt tacacgttgg
      301 ttgaagcaat atgaaagatg aggtaaagaa tggctaatag acgaatgttg agtaaaacgg
      361 tggtgcagat acaacgattt ttacgcctac cacttgaagc gcaggcgctt tactgtcact
      421 tggtagtcaa tgcagatgat gatggtattg ttgaagcttt tcctgttatg cggatgatta
      481 atgctaatga ggacagtttg aatttattaa ctcttaagca gtatttactc ttgttaaaca
      541 atgaaatggt ttactttatc aaggatttct ttgagcagaa taccatcaaa gcagatcgtt
      601 acacaccgag tagtcatcgt caacttctta tagattatct gaaggataat cagttgttgg
      661 agtgtctaaa tctaggacca cgcttgatta attatcttca aaatactcgg ctccaagttg
      721 gagccagtct ggatccagat gggaaccgca atataattaa agataagata agtaaagata
      781 ggataggtaa agataagtta agtcaagata agataggatt agataatgat ccaatctcat
      841 cacaactgac tgatgacatc tggttaatgg aaacactatg gcatcgagaa ttaacccaac
      901 aggagaaagt attattagaa ggattcgcgg ttaatgattc tttattgcag ttagctattc
      961 agaaaacaga ggagcttgag ccaaagaaac aaaacatgag ttatgtcaaa gggatactaa
     1021 tgaattggga agctagaggg tttataactg ttgaccaagt gatagcatct gaagaagact
     1081 accgtccatt agaaattgca aatgtagaag tttcagaaga tttcttagca gctatggata
     1141 tatggaaaga ctaggggaat aatgagttat gacagtatat tatcaattag aaaatatgtt
     1201 agtggctggg tttaagtcac aagatgagta cgaccgctat caggctctca agagggacta
     1261 tgaaggggag tcagaggact atagcttttc aatcagagaa atcacaaatc aacttgaaat
     1321 catttgtcag acctcagaga atgattttcc gaacttatca gaagcattaa tgattgatta
     1381 tttagaactg gtaggagagt tgaaacgata tgatactaat caggcagaca ggtatttagg
     1441 gatggttcgt catgtctgaa cgtatcagaa ctattttaaa gaagttttat gtgacggaat
     1501 tgcagaatga agtacttaat caactagtaa atgatacagg cttgcaaaca ttctctaatt
     1561 atgctcgtcg gatgcttttt aaggaaacat cactctttat gcgatttgat gaatctcagt
     1621 ttgatgagtt gatttattct ttaaggcgta ttcaaaataa tttaaggcag ttatctaaaa
     1681 ttgcagagca gtctcaagat agtcaagcct acagagctat ggactatagc agaaggttag
     1741 tttcacatta tgaaaagcag ttaacgcgtt accacaagaa aaagaaacgg aaattattat
     1801 ctaagggagc ttaatggata aaaggagaat taggaacgta attaaacaag tctttttgtc
     1861 tgaagaagaa aatcaaaaac tgttagagaa aatgaagcaa gatggcttca caaacttttc
     1921 tctttttgct agaaagcaat tattaaaacc tgattttgaa acttggctag ttagttttcc
     1981 agaatatcag ccgctgactg gcaggttact atctgttggt agaacaatta atggcatcgc
     2041 taaaagcgca acacagtttg gaaaaatttc ccaacatgat ttgatggaat taggtcagtt
     2101 gatggaggaa cttgtagaac tggtagagaa acaagtgaag gaagacaagc aacgaatagc
     2161 caagaagtga tagtcgttca gtcattttgg tagaatagtt ttaaataaaa caacaaaaac
     2221 gctgatggta gtcagcgttt tttagcatgt aattgtaaaa aatccttgta cggacaatgt
     2281 gcggcaccgt ataaagtacg ggaaatcact aaaaatggag ttaggtcttt gcgagctcag
     2341 atagtgtata cacactatcg taaaaataga accatcagta aaggtcagac tgacactttt
     2401 tgattgatgc ttatatttta ttttggggca aagccccaaa ccccttgaga aaacgtgtga
     2461 gaagtaggga aaaatggtat aatagaaata ttaaagactg tgaggatttg aagatgtcag
     2521 aacaagcaca aaggcaagag ttgcaccgca aaatctgggc aatcgcagat gatgtccgtg
     2581 gtgcggtaga tggttgggat ttcaaacaat atattttggg aatccttttt taccgtttta
     2641 tcagtgaaaa tttcaagact tatatcgagg gtggtgagga cttcaactat gaggagattc
     2701 cggatgaagt aatcacacct gaggttaagg atgatgcgat taagacaaag gggtacttta
     2761 ttatgcctgc gcagcttttt tccaatgttg tgaaaacagc tcgtagtaat gacaacttaa
     2821 atacggaact caaggatatt tttgatgcca ttgaggcgag tgctatgggt tatgccagtg
     2881 aaaatgatat taaaggtctt tttgatgacg tagacaccag aagtaataag ctaggaagta
     2941 ccgtcccaga gcgtaatgaa cgcttagccc ttatcctaga aggtattgcc agccttgatt
     3001 ttggtagttt cgaggacaat catatcgacc tttttggcga tgcctatgag tttctgattt
     3061 ctaactacgc ttctaacgcc gggaaatcag gcggagagtt tttcacaccg cagagcgtgt
     3121 cacggctcct agcacgtatc gtcatgttag gcaaggatga aaagaacaaa atcaataaga
     3181 tttatgaccc tgcttgtggt tctggttctc tcttgcttca agccaaaaaa caatttacgg
     3241 agcatattat cgaggatggt ttttatggtc aggaaatcaa catgaccacc tacaacttgg
     3301 ctcggatgaa tatgttcctt cataatatca actacgacaa gtttagcatt gagcgtggca
     3361 atacgctgct ggaccctaag catggcaatg ataagccctt tgatgctatc gtgtccaacc
     3421 cgccttattc aatcaagtgg gttggtagcg atgacccgac gctaattaat gatgaccgtt
     3481 ttgcaccagc ggggattctg gcacccaagt ctaaagcgga ttttgctttt atcatgcata
     3541 gcctttctta tttgtccaat aaaggcagag cggctattgt gaccttccct gggatttttt
     3601 atcgtggtgg agcggagcaa aagattcgtc agtatttggt agacggaaac tttgtcgaaa
     3661 ctgttatcca attgccggat aatctccttt ttgggacgtc tatcgctacc tgtatcctta
     3721 ttcttgctaa gaataagccg acaacagatg ttctcttcat tgacgctagc cagcagttca
     3781 aaaaagaaac caataacaat gtcttgacag aagagaacat cgagaaaatt ctgaaaagtg
     3841 ttgagcataa gaataatgaa gagtattttg ctcagctcat ttcccaagaa aaaattgtgg
     3901 aagctgacta caatctctct gtatctacct acgtggaaaa agaggatacg cgtgagaaga
     3961 ttaatattga tgtattaaac aaagaaattg ctgagaccgt gaaaaatatt gaccgattgc
     4021 gggcagagat tgataagatt gtcgaggagt tgagctgata tgacctacat tgatgagatg
     4081 attaaagagc tttgtcctga cggagtggag tggaaagagt tgggtgaagt cgttgactac
     4141 gaacagccaa caaagtatat cgtaaaatct aaggaataca gcgatgatta ttccattcca
     4201 gttttgacag caggtcagac atttattctt ggatacacaa atgaagtaac tggtatttat
     4261 ccagcaagta aggaacatcc agttattatt ttcgatgact ttacgacagc tagaaagtgg
     4321 gtggattttg aatttaaagt taagtcctcg gcgatgaaac tactctctat caagtcagac
     4381 cgtcaagatg atgtttcaat aaggtatgtt tggcactatt taggaacaat aaaatacaca
     4441 ccagaacagc acgcacgaca gtggataggg actttttcta aatttaaaat cccccttccc
     4501 ccactagaaa ttcaagggga gatagttaaa atacttgaca aattcacgga acatgttaca
     4561 gaattgaccg cagaattgac cgcagaattg acctttcgac agaaacaata ttcttatttt
     4621 agagataagc tcctaagttt tgatgatgaa agtatgggag gggcgaacga taaggtttac
     4681 actgtccagt ggaaaacgct gggggaggtg gtgaatttta ggagagggtc tttccctcag
     4741 ccttacacag atatgtcgtt ctatggtgga gaagatgccc aaccatttgt tcaagttgta
     4801 gatgttgctg atgaaggatt tagactgaat actaaaacga aaaaaacaat ttctcaaaaa
     4861 gctattccaa aaagtgtttt tgtacctaag ggaaccgtta tcgttacctt gcaaggcacc
     4921 ctaggaaggg tagcggttac ccagtatgat gcttatgtcg atagaacgtt agcaattttt
     4981 gacggttata agcaagaagt tgataaacgc tatttcgcac accaattgaa gtttattttt
     5041 gacagagaaa aagaatttgc tagaggaagt actctgaaaa caataacaaa acaagaattc
     5101 tcgaatttca aaatcccagt ccctcctctg gatattcagc gtcgtattgt ccaagttttg
     5161 gataattttg atacggtttg taatgaccta aatatcgggc tacctaagga gattgagctt
     5221 catcagaaac agtatgccta ttttagagac aaactcttga ccttcaccgc cgaaggcgtg
     5281 tatactgaca gtacagtaca gtacagtaca gtacagtaca gacaagacct aattaggctc
     5341 ttgacttggg tttttggacc gattaaggtt gagttggggg ctgtctgcga tgtggtgcgt
     5401 gggaatggtt tgcaaaagaa ggattttgtt aatgagggtt atcctgttat tcattatgga
     5461 caaatctata ccttctatgg attgagtgct cgcgtgacga aatcttttgt gtcaccagaa
     5521 gttggtcaaa aattgaaaaa agctaaaact ggtgatgtga ttgtagctac tacttctgaa
     5581 aatattgaag atgttggtaa agcacttgtt tgggaaggtg ctgaagatgt ttgtattggt
     5641 ggacactctt gtgtattgca cacggaacaa aactcgaagt acttgcttta ttattttcag
     5701 acaactgtgt ttcaaaagca aaaggaaaag ttagtgatag gaactaaagt gattgaactg
     5761 tatcctaaaa atttagaaaa ggcgattatt attctcccac ctgtatacga acaagggcgt
     5821 atcgtctcca ttcttgacaa atttgataca ctaacttctg accttaccca aggtcttccg
     5881 aaagaaattg agcaacgaca gaaacagtat gagtattggc gggatttact acttaacttt
     5941 ccgtaggagg aagaatagat atgggaaatg atatcaaatt tgaaaattta gaacagattt
     6001 cggataatat tatttctagt aataagaaag ttcatttgct atatgcctat aatgctactg
     6061 ggaaaactag gctttctatg gaattgaaaa ataaggtaaa tgagactgat agtgatggta
     6121 atagcattaa gcacatttta tatttcaatt catatacgga ggatcttttt acgtgggata
     6181 atgatttgga aaacgatgaa gatcgatatt tgatttatga taaacgaact tattttggaa
     6241 atttccttga agagcaacaa cttttcgaac gtgctgtaga caattttcaa aagtatgttg
     6301 gtagatctat tgatattgag ttccaagatg ttattgaaac agttaaagat gagttcggaa
     6361 atgttcaaaa agataatagg ggtgaggcac taacaattag taataaaaag agtataagat
     6421 ttaaagtaga tgggcataca ataaaggtgt ctagaggaga agagaggatt tttgtttggt
     6481 cagttttctt aacgctcctt gaaattatta ttgaagattt gactgagtct gctgatacct
     6541 cagaattttc aaaaatgaac tatatctata ttgacgatcc tatatcttct ttggatgata
     6601 ctaatattat taatgctgca atttatttga gtgatgttat aggtagtgct gaaaatactg
     6661 atttgaaatt tgtcgtctct actcatcaag cattatttta taatgtactt tataatgaaa
     6721 tccgatttga tagaagaatc aagaaaaagg ttttttacgt catgaaagct actgatgaaa
     6781 ttgaggatga gaaacaattt aaatatttgt tgacagatgt tgaaggggat tctccatttg
     6841 gatatcatct cagagtgaga gaagaattga gaaaagcaat tcaagatgaa caggtagaga
     6901 aattccattt tgctcttttt agaaacctag ttgaaaaaac agcaacattt ttaggatatg
     6961 gacgatggga aaatatcttg ttaggtttag atgttgctgg acatgttata acatctgaaa
     7021 atattaaact ctatacacaa ctgattgatt tatacactca taataggcat gctgatttag
     7081 aatatagaga attgcctccc caagagaaaa atactcttat aaatttattt aatagctttg
     7141 attcaatcta tcgatttaaa gaggactaac tatgactgaa atcatccaaa cagatactat
     7201 tttagaggct aagaacttca ttgtactgga aaaatacacc aagttggaaa agcctagcac
     7261 ctatcagacg gaagcagact tggagcgaga gctggttagc gatttgcggc agcagggata
     7321 cgagtacctc aacaatctga cgaccccaga agctctctta gataacctaa agacccagat
     7381 ggaagccctt aatggcgtgg ttttttctga ggcagaatgg ctgcgttttt tagaggagta
     7441 cctcaataag cctagtgatg gtttgattga ccgcacccga aagctccacg ataaccacat
     7501 ctacgacttt atctttgacg atgggcatat ccaaaatatt tatctctggg ataagaaaaa
     7561 tatcagtcga aataagcttc aggtcattaa ccaaatgtct caagttggga cttcaagtaa
     7621 ccgttatgat gtgaccattt tggttaatgg gctaccctta gtacaaattg agcttaaaaa
     7681 gcgtggggtg gctattcgtg aggctttcaa ccaggttcac cgttacagta aggaaagctt
     7741 taatgaggaa aattcgctct tcaagtatct ccagattttt gtcatttcaa atgggacgga
     7801 tactcgctat tttgctaata ccactaagcg agagaaaaat tcttttgact ttaccatgaa
     7861 ttgggcacta aaaaataatg agccaatcaa ggatttgaag gattttacag cgaccttctt
     7921 cagtcagcag acactcttaa acattctcat caactactca gtttttgata ctagtgatac
     7981 cctcctaatc atgcgtccct atcagattgc tgcgacggag cgcatcatct ggaagattcg
     8041 ttcggccatt gatagcaaaa tcaagagtgg tcctgagact ggcggctata tctggcatac
     8101 gacggggtct ggtaagacct tgaccagttt taaggctgcg agactggcga ctgagatgga
     8161 taaagtggac aaggttttct ttgtggttga taggaaagac ttggactacc agactatgaa
     8221 agaataccag cgtttttcac ctgactcagt taatgggtca aatagcacag ctggacttaa
     8281 acgcaatatc gaaaaagatg acaataagat tgttgtgacg acgattcaaa agctcaataa
     8341 ctttatgtct agtgaagcac agcatgagat ttacaacaag caagtggtct ttatctttga
     8401 cgaatgccac tgttcacagt ttggcgaggc tcaaaagcgc ttaaaacaaa agtttaagaa
     8461 gtattgtcag tttggtttta caggcacgcc gattaaagtt gaaaatgctt taggcagtga
     8521 gacgacagct tctgtattcg gtcgggagct tcatgcatac gtcattactg atgctatccg
     8581 tgaccaaaag gtgttgaaat ttaaggtgga ttataatgat gttcgtccac agtttaagtc
     8641 gttagaaact gagcaagatt tagggaaatt atctgctgct gaaaataaaa aagccctact
     8701 tcatccaaca cggattacag agatttcggc ttatatttta gaacatttta atcaaaagac
     8761 acataggcaa aacggtaaag gatttaacgc tatgtttgct gtgtcaagtg tcgaggcggc
     8821 caaggcttac taccaagagt tgcaagacca acaagctgga aaagctaaac cattgaagat
     8881 tgcaaccatc ttctcttatg cagcaaatga ggagcaggct gcgattgggg agattgatga
     8941 cgagactttc agccctgctg acttgtcaga tattagtagt aaggaatttt tgagcggagc
     9001 gatttccgat tataatcgcc tttttcagac taattttagt atcaatggca atgagtttca
     9061 aaactattac cgtgatttag ctaagcgagt taagtctgga gaagtggatt tgctgattgt
     9121 cgttggtatg tttttgactg gttttgatgc accaaccttg aatactcttt ttgtggataa
     9181 aaacttgcgt tatcatgggc ttattcaggc tttttctcgg acgaatcgga tttataatgc
     9241 gacaaagaca tttggaaata ttgtaacttt ccgtgatttg gagaaggcta cgacggatgc
     9301 tattaagttg ttcgggaaga cggagacggc tgatattctg ttagagcgct cttacgagga
     9361 ctacatgaat ggctacattg aggctggtca agagcaaaaa ggatatttgg aagtcgtaaa
     9421 agaattgcag gagagatttc cagatccaac gactattatc aaagaaagtg ataagaaaga
     9481 atttgtgacc ttgtttggtc agttcttgcg cttggataat atcttgcaga actatgatga
     9541 tttcatgagt ttgcaggctt tgcaagagtt agatgttaca gatatagagg ctttggcaga
     9601 tttcaaagga cgttttcatt tggatgacga agcagttgca gtactctctc aactggacat
     9661 cccaagtgtt cgtgagattc aagattatcg ctccgcttac aatgatatca agtcttggta
     9721 tgacaatgag cggcgtaatc agcagaataa cgattccgaa atcgactggg atgcggttgt
     9781 ctttgaagtg gagttgttga aatcacagga aatcaatctg gactatattc tggaattgat
     9841 ttttgaaacc aaccaaaagg tatctgacaa ggatcaactc attgaagaaa ttacacgaac
     9901 tatccgtgct agtctgggtc agagagctaa ggaaagtttg atcgtggatt ttatcaatgc
     9961 cagtgacttg gacagttttt ctgagaagtc agatatcttg gagcaatttt atacatttgc
    10021 ccgtcaaaaa caaaaagaag cagtggctaa tttgattgag actgagggat tgaatgtaga
    10081 gagtgctagc cgctatattc agatgtcact caaacgagag tatgccagtg aaaatggtaa
    10141 tgctctcaat gaagcacttc ctaagatgag tccgctcaat cctcaatatc gtaccaaaaa
    10201 gcagatggtg tttgaaaaaa ttgtggattt ggtggagata tttaagggga ttggtggaga
    10261 aatttaatta ttattatttc ttctagatat agaagagata aactttaaat tagagcttga
    10321 aattttaaga aatattaagg catcatatca gtagtataaa aagctgactt ataatttatt
    10381 tggaaacgac agttaatcct aaaatacgat gcttgatatg gaggaggctt aaacttggaa
    10441 aataaaaagg atttaattca aaccttagcc tactaccaat tctcactaga aaaccaatac
    10501 ttggatagaa aatcagcacg aaagaagccg caagaattac tcaagcatct gattgctttt
    10561 gccaatgcgg acggcggtca gttggttatt ggtattgaag atgagaagca ggacaatatt
    10621 atcactggtt tcaaggatgg cagagcttat cccatagacg atttcaaaaa aattgaccat
    10681 gagatgcggg agactcctct ggatttgtct ttagaggaaa tccctgtgct aaatcataag
    10741 ggagaagatg acctgatttt ggttatttct gttgaattat cgtcgaaccg agtgattgct
    10801 gcgcctaatg atgaggttta tctgcgtcag ggcgatgaat cggttaaatt aagctatgag
    10861 caacgtactc agcttagcta tgataagggc caacgtttct ttgaagatga agtggtacct
    10921 gatgcgacct tggaagatat tgatgatggg ttagtccagg acttcaaaaa tcggtttgat
    10981 atttcagagc gctccatgga agaagttctt aaagcaagac gattcttggt taatggtaaa
    11041 ttaactaagg cagcgattct actctttgcc aaatatccat cagcgttttt tccacaagct
    11101 cgtgttcgtt ttcaacggtt tgacgggacg gatatgggaa caggcagtag ctttaatgtt
    11161 attaaagaag taacttttga tgatgctctg cccaccttaa ttatcaaagt gcgagatttt
    11221 atccgtactc agctgcgtga atttcagtac ttagacgata atgggcaatt ccagattttg
    11281 cctgagtatc ctgaatttgc ttggtttgag ggtgttgtca atgcggtgac tcaccgtgat
    11341 tactctgtct atggggatca cattcgtgta ctcatgtttg atgatagact ggagattcat
    11401 agcccaggga aattaccaaa tatcgttacc gttgacaata tcaagcatga atgtttttct
    11461 agaaatcctc ggattgcgag aaccctgact gaatttggat gggttcgtga gatgaatgaa
    11521 ggagtgaagc gtatctattc tgagatggaa tcagcttttc ttcatgaacc taaatattta
    11581 gaaccaggta ataaggtagt tttgaccctt gaaaataaca tcgtgagtcg acatctccga
    11641 acacgagata gtttggaaaa acaattttct gattttggaa atctgactgc agatgaacaa
    11701 gctatcgttc actacatgta taattctggc gataaaatga caacagcaaa ggcgattgag
    11761 ttgacaggga gaagtcgttc gtttgttgtc aaaatgctac atcatcttcg tgatttagaa
    11821 atcatcactt ggtttggttc aagtaaaaat gaccgtaatc aatattatct tttagttgat
    11881 aaatgattgc agccaggata cttattagta ataagaatac agtagaatac agaaaaagtg
    11941 gtgtt
//
LOCUS       DARYXS010000065        11338 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.066, whole genome shotgun sequence.
ACCESSION   DARYXS010000065 DARYXS010000000
VERSION     DARYXS010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11338
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.066"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(193..1239)
                     /locus_tag="TV193_001413"
     CDS             complement(193..1239)
                     /locus_tag="TV193_001413"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEL1513596.1"
                     /translation="MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFIS
                     QTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAE
                     TEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEV
                     GLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAF
                     KAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVR
                     LAQEMFEKREGHLI"
     gene            complement(1387..1983)
                     /gene="recR"
                     /locus_tag="TV193_001414"
     CDS             complement(1387..1983)
                     /gene="recR"
                     /locus_tag="TV193_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEL1513597.1"
                     /translation="MLYPIPIAKLIESYSKLPGIGVKTATRLAFYTIGMSDEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDSSRDKEIILVVEDSKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMAGEATEVIVATNATADGEATAMYISRLL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            complement(1995..4049)
                     /locus_tag="TV193_001415"
     CDS             complement(1995..4049)
                     /locus_tag="TV193_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEL1513598.1"
                     /translation="MASWIKKKKASIPRRIHLLFLVIVFLFVALILRLAQMQIYEKDF
                     YKAKLTASTVYKVKSSMPRGTIFDRNGKVLVSNRIKDVVTYTRSPKASAKDIKALAHQ
                     LAAYISYPEAKVTVRAKKDYYLADPEAYAKTVQALPQKDKVDRFGNKLVEAQIYQNAA
                     ASLKETDLTYSDQELKVIAIFNQMNAAAVFSTVKLKTSALSEQDIAIIMANKSKLPGI
                     SVGTDWERQVEETSLAAIIGRVSSEEAGLPKEEAKAYLKKGYSLNDRVGTSYLEKQYE
                     EVLQGKHEIREIKTSRSGEVISDKIVEKGQMGRNLKLSVPLDFQQGVEQILNQHFQTE
                     LKNGQAAYSEGIYAVALNPNTGAILAMAGLSHNPKTGELQKDALGTITDVFTPGSVVK
                     GATLAAGWQAGVIQGNQVLIDQPIQFGGSQPINSWFTSGQHPITASQALEYSSNTYMV
                     QVALRMMGQDYVTGMTLANTGMKETMKKLRAAYAEFGMGVATGVDLPGESSGYLIDQY
                     NTANVLTEAFGQFDNYTTMQLAQYVSTIANGGSRLAPHIVEGIYQDNDQSGPGKLSKA
                     IETTLLNKVHLAADSLAIIQDGFYQVVNSGSGYATGRALAGGPVTISAKTGTAETYAK
                     DKNGQALSTFNLNVVAYGPSASPQIAVAVMYPHATDSLAKAHQYVAKDIINLYMKMYK
                     NQ"
     gene            complement(4161..4931)
                     /locus_tag="TV193_001416"
     CDS             complement(4161..4931)
                     /locus_tag="TV193_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEL1513599.1"
                     /translation="MKTPEQILAATITIGEHKVAKPFLAKAILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSILGACAFPIGLIIILMAGGELITGNMMAVSAAFFAKKIKAKD
                     LMANWLVITLFNILGALFVAFVFGHFLGLTATGSFKEEVIEVAHAKLAATPLQAIVSG
                     IGCNWFVGLALWLCYGASDATGKLLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     SWIDFATNFALVYVGNVLGGAIFVSLFYYKAYDHSKEA"
     gene            complement(5070..5609)
                     /locus_tag="TV193_001417"
     CDS             complement(5070..5609)
                     /locus_tag="TV193_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513600.1"
                     /translation="MTKKPTQLIAYSSILVAFAILIPMIMPIKLIIGPASFTLASHLP
                     LFLAIFISIPVAILVGIGTGLGFLLAGFPMIIVMRAFSHVLFAAIAAFMLKRQPKWLE
                     TPLRTFVFGIIANVIHGLAEFLVVYLMTATAATDLSYFWSMLMLVGFGSLLHGMVDFY
                     LALFIWRFLRQKGHLSVTS"
     gene            complement(6004..6525)
                     /locus_tag="TV193_001418"
     CDS             complement(6004..6525)
                     /locus_tag="TV193_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEL1513601.1"
                     /translation="MKVKERREAITDRLSQAQEAISATSLAKALGVSRQVIVGDIALL
                     RAQQLDIISTPKGYILSNALFSHHYSARIVCQHGPEQTRQELELILAHDGIVTNVEVE
                     HPIYGMLTAPLNIKSSADINNFIEKLGASKAELLSSLTEGLHTHLLSCPDQEAFEEIK
                     RDLAAAGILYGEQ"
     gene            complement(6634..7329)
                     /locus_tag="TV193_001419"
     CDS             complement(6634..7329)
                     /locus_tag="TV193_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1513602.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
                     PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDD
                     KLNLTAEYYLGGE"
     gene            7572..8507
                     /locus_tag="TV193_001420"
     CDS             7572..8507
                     /locus_tag="TV193_001420"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEL1513603.1"
                     /translation="MVSTATKIATFAFNNCLMNAAGVYCMTKEELLAIEASEAGSFVT
                     KTGTLAPRQGNPEPRYADTALGSINSMGLPNHGYQYYLDIVTEMQKDQASKHHFLSVV
                     GMSAEETETILKAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDQLLKKIFSYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNQYPLAFANCVNSIGNGLVIDDEQVVIKPKNGFGGI
                     GGDYIKPTALANVHAFYQRLNSSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQE
                     GPAIFKRITKELQDIMAEKGYQTLDDFRGQLQYKP"
     gene            complement(8552..8725)
                     /locus_tag="TV193_001421"
     CDS             complement(8552..8725)
                     /locus_tag="TV193_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513604.1"
                     /translation="MPIIVILGLAIFSVVKVIIFLCFYKAFEKKQLKKLEQDQKETKQ
                     AIDQEESKKAFPF"
     gene            9094..9987
                     /locus_tag="TV193_001422"
     CDS             9094..9987
                     /locus_tag="TV193_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1513605.1"
                     /translation="MTNHQLGKAFRSIRQNRNITLQQLASKDVSLSQLSRFERGESDL
                     SVTKFLTALDSMQVEISEFMDIAANFKQTEQIQFMSQLIKLEYARDIEGFKQLQKQEL
                     AKHQADPDTNRYYLNSILLQGFICKCNPSIPFPKAYLDEVTDYLFRTESWHIYELILI
                     GNLYLFIDIPLLDKMGKEILNNHTYYESISTNKHLVTITLLNIWETCIHRHQLDYARY
                     YQKQILALLNNETKLYEKTIFLFLKGLEDYQRGQCLSGIKDMTTAISIFESLDCPHLA
                     HNYQKDFERFVASSSLICKKT"
     gene            10042..11250
                     /locus_tag="TV193_001423"
     CDS             10042..11250
                     /locus_tag="TV193_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1513606.1"
                     /translation="MRKNDYQLLASRAINKIGNTVYDYSNSSGIAGLGATGRQYLGYY
                     QLAEGLISLILNPIGGAIADRYKRRQLLLWTDAIGAISCGLLALIANPTIMLYGLITV
                     NALLAISYAFSGTAFRAYVVTLVETERLVHFNAQLEIVSQIISISSPMLAFLVMDCFG
                     IKTALALDSISFLLSFLCLYTIKDKERHITKQSSQGNRLQLLTDIKEGLQFIYHDNDI
                     FSLLIIASLVNFFIAAFNYLIPFSNQLLGSQSSYASLLSMGALGAILGAFMANKLFKN
                     NQQSLLLSLGLSGLGMLLITAMALLKLPVIVIALGNLWFECFLTIFNIHFFSIVQKKV
                     PEALLGRVFSSIVTTAILLMPLATTIMTCIPASVHLATFAVIGIGIMATASLAYYCNY
                     RQSSKKKPFI"
BASE COUNT         3383 a         2675 c         2097 g         3183 t
ORIGIN      
        1 tatagcataa catattagga atattctttc tatttcactt tatgcctaca ggctgatcct
       61 tcatagacag gctaaagctg gcacagccaa ccgtagacga tagggcttta aaggcttctg
      121 accaaaaaac gctaccaatc aggccaaacg aaaggacaga ggattgctat atctccttcc
      181 gtcctttgtc tcttatatta aatgcccttc acgcttttca aacatttcct gtgctaatct
      241 gactagctcc tcaataagct cagcatagct cagtcccata tgctcccaga gcaagggata
      301 catggaccac tgcgtaaagc caggcatggt atttaattca ttgaggtaga tctgaccgtc
      361 ctgaccaagg aagaaatcac aacgcgacag gccacaagca ccaatagcct taaaggctgt
      421 ttctgcgtag gtacgcatgc ttgtcatagc tgattcgtca atagctgccg gaatagccat
      481 tgtgatctca ttatcaatgt atttggcctg ataatcataa aagtcaacat tcttgactac
      541 ctctcctgga agggttgatt tgacatcggt attaccaagc agtccaacct caatctctct
      601 tgccaaaacc ccttgctcaa tcaggatacg actgtcatac gtcaaggcca acaggatagc
      661 tgcacgcaac tcctcctctg attctgcctt agaaatacca acagatgagc ccatattggc
      721 cggcttaaca aacacagggt agcttaagac tgcctcagtc tctgccagac acctgtctaa
      781 atcctgcccc tcaatataaa cggtataagc aacctgtggg ataccagctg actctaggac
      841 ccttttggtg gtaatcttat ccattgcaac acttgatgag aggatattag ttcccacata
      901 aggcattttt agcacctcta aaaagccttg aatagaaccg tcctctccca tagggccatg
      961 caagactgga aaaacaacag ccccctcctc gtagatatca ctaggcctta tctgctgctc
     1021 tagcctaata gtgtcgttgg tcatcagcct ttctgttaag gtcggccgac tagagaattc
     1081 ctgtgtcttg ataaactgac ctgtctggct gataaaatag gttttaacaa aaaatttggt
     1141 gtaatcaact gctctcatca cgctctcagc tgaaagcact gatacttcac gctctgccga
     1201 acgccctccg tataataaaa ttaaggtttg tttagacatt gataaccttc cctatctgaa
     1261 ttagactacc acttattata acaaaaacga gcttgctttt caaaagactc tgacaaaatc
     1321 tgccttcctt tatggcctta tcacatggca taagggctaa tgacagagag ctgaaaatgg
     1381 gctaagctat aattctgtcc gattttcaat cgctcgcagc agggttacct catcagcata
     1441 ttcaatgtct gatcctactg ccaagcctct agccaatcgc gtcaccttga taccagcagg
     1501 ctttaggaga cgtgagatgt acatcgcagt cgcctctcca tctgctgtgg cattcgttgc
     1561 aacaatgacc tctgttgcct ctccagccat caaacgcgtg attaggctct ttagattgat
     1621 gtcatctggg ccaaccccat tcatgggaga aatcaagcca tgcagcacat ggtaatagcc
     1681 atgatattct tgaatttttt ccatggcaga aacgtccttg gaatcctcaa caactaaaat
     1741 gatctcttta tcccgactgc tatctgtgca aatatggcag ggatcatcat ctgtcaaatt
     1801 gccacagata gagcaatagg ttaattctcg cttagctgct aataaatttt tggcaaaatc
     1861 attcacatcc tcatcagaca ttccaatggt gtaaaaagcc aatcttgtcg ctgttttaac
     1921 accaatccct ggtaatttag aatagctttc aattaatttt gcgattggta tagggtaaag
     1981 cactcgtttc tcctttattg gtttttatac atcttcatgt acaaattaat gatatcctta
     2041 gccacgtatt gatgtgcctt ggctagagag tctgtcgcat gaggatacat gacagcaaca
     2101 gcaatttgag gactagcact cggaccatag gcaacaacat tcaagttaaa ggtagataaa
     2161 gcctgaccat ttttatcctt agcataggtt tctgcggtac cggttttagc actaatggta
     2221 acaggacctc ctgcaagagc cctacctgta gcatagccac taccgctatt gaccacctga
     2281 taaaaaccgt cctgaataat cgctaaacta tcagcagcta agtgcacctt gtttaacaag
     2341 gtagtctcaa tagccttact tagcttacct ggtcctgact ggtcattatc ctgataaatg
     2401 ccttctacaa tgtgaggcgc aaggcgactg ccgccattag caatagttga gacatattgg
     2461 gccagttgca tggttgtata gttatcaaac tgaccaaagg cctctgtcaa aacatttgca
     2521 gtattatatt gatctatgag gtagccactg gattcgccag gcaaatcaac gccagttgcc
     2581 actcccatgc caaattcggc ataggctgcc cgcaattttt tcatggtttc cttcatacca
     2641 gtattggcca aggtcatacc agtcacgtaa tcctgcccca tcattcttaa ggcaacctga
     2701 accatgtaag tatttgatga atattccagc gcctgactag cagtaatagg gtgctgaccg
     2761 ctggtaaacc aagaattaat cggctgggag ccaccaaatt gaatcggctg atcaatcaag
     2821 acctgattcc cctgaatcac tccagcctgc cagccggcag ccaaggtcgc ccccttgaca
     2881 acagacccag gtgtaaacac atcagtaata gtccctaaag cgtccttttg aagctcaccg
     2941 gttttgggat tgtgtgatag acctgccatc gctaaaatcg ctcccgtatt agggttaagc
     3001 gccacagcat agatcccttc tgagtaagca gcctgaccat ttttgagctc tgtctggaag
     3061 tgctgattca agatctgctc aacgccctgt tgaaaatcaa gtggcacgct caacttcagg
     3121 ttccgcccca tctgaccctt ttcgactatt ttatctgaaa taacctcacc agatctgctc
     3181 gttttgattt ctctgatttc atgctttcct tgaaggacct cctcgtattg cttttccaga
     3241 taagaggttc caacacgatc attaagcgaa tagccctttt taagataagc ctttgcttct
     3301 tcctttggaa gaccggcttc ctcactagag acccttccaa taatagcagc aaggcttgtc
     3361 tcctccacct gacgctccca gtctgtccca actgaaatac ctggtaattt tgacttattg
     3421 gccataatga tggcaatatc ctgctcagat aaggctgatg ttttgagctt tacagtgcta
     3481 aaaacagctg ctgcattcat ttggttaaaa atagcaataa cctttagctc ttggtctgaa
     3541 taggtcaagt ctgtttcctt aagagaggct gccgcatttt gatatatctg tgcttcgact
     3601 aatttattac caaagcgatc caccttgtcc ttttggggta aggcttgaac cgtcttagca
     3661 taagcctctg gatctgccaa ataataatcc tttttggctc tgactgtcac tttagcctca
     3721 ggatagctaa tataagcagc tagctgatga gccaaagcct taatgtcctt agcactagcc
     3781 ttgggacttc tcgtataggt taccacgtcc ttgatacgat tagaaactag aaccttccca
     3841 ttacggtcaa aaatggttcc ccttggcata gagcttttta ctttgtaaac ggttgacgct
     3901 gtcagctttg ccttgtaaaa atccttctca taaatctgca tttgtgccaa tctcaaaatc
     3961 agggcaacaa acaaaaaaac aatcaccaaa aaaaggagat gaattcgcct aggaatgctt
     4021 gcttttttct tttttatcca tgatgccata ttagatgctt atcaactcct cctttttaaa
     4081 cgtcgtttcc tattttatca caaaatataa aaataagact gagaataagg tctcccagtc
     4141 taaaaatata acagcactaa tcaggcttcc ttagagtgat cataagcctt gtaataaaag
     4201 agactaacaa agatagcacc gccaaggaca ttgcccacat aaacgagagc aaaattagtc
     4261 gcaaaatcga tccagctggc gccaccctca aaaatagccg ccggaataac aaaggcattg
     4321 gccacactat gctgaaaacc aagggcaaca aaggtcatca caggaaacca ggttccaagg
     4381 agcttacctg tcgcatcact agcgccatag cacagccaaa gcgccaggcc aacaaaccag
     4441 ttacagccaa ttcctgaaac aatagcctgt agaggagttg cagcaagctt ggcatgggcc
     4501 acctcaatga cctcttcttt aaagctgcca gtagctgtca gacccagaaa atgaccaaaa
     4561 acaaaggcaa cgaacaaggc tcccaaaata ttaaaaaggg taatcaccag ccaattggcc
     4621 atcaagtcct tggccttaat cttttttgca aaaaaggctg ccgacaccgc catcatgttg
     4681 cctgtgatca attcaccgcc agccatcaaa ataatgatca gcccaatcgg aaaggcacaa
     4741 gcacccaaaa tactagaaaa agcgccaaag gtctccagcc cactagctgc aatcctaaca
     4801 tacaataagt agcccaaact aatcatcgca ccgccaataa agcctaaaat agccttagcc
     4861 aaaaaaggct ttgcaacctt atgctcacca atcgtaatcg tcgcggctaa tatctgttct
     4921 ggtgttttca tgacatctcc ttttgttagt atatttacaa acgcactctt tagtatagca
     4981 ttttttcaaa aaaatgcaag cgctttcaga aaaaagagcc tcagcctgta acagccttgg
     5041 ctactaaaac ataaatactc acagaaatcc tagcttgtca ctgatagatg acccttctgc
     5101 cttaagaagc gccagataaa taaggctaga taaaaatcca ccataccatg cagcaaagac
     5161 ccaaagccaa caagcattag cattgaccaa aaataagaaa gatcagttgc tgctgttgct
     5221 gtcatcagat aaaccactaa aaactctgct aggccatgaa tcacatttgc tataatccca
     5281 aaaacaaagg ttcttaacgg tgtttccagc catttaggct gccttttgag cataaaagcc
     5341 gcaatagctg caaaaagcac gtgtgagaag gctcgcataa caataatcat aggaaatcct
     5401 gctagcaaaa agcccagacc tgttcctatc cccaccaaga tcgctaccgg aatggatata
     5461 aatatggcta aaaacaaggg cagatgacta gctagggtaa aggaagccgg gccaataata
     5521 agcttaatgg gcattatcat cggaatcaag atggcaaagg ccaccaaaat agaagagtag
     5581 gcaatcagtt gtgttggttt tttggtcata atatctcctt ttactagtcg ttagtataac
     5641 caaaaacgcg acagatgtca agacacctag caaatcaaaa aacaaccaca gcataagctc
     5701 aatcccagcc cttctcaagc accaaaagct aagacaaaag acagacacat ctcagccatt
     5761 gcagcaccaa gccctgcggc ctaacagcat aaaagattat cctagcaaaa aagtaagggt
     5821 aaatctagcc ctttcaccat aaccatagca gcttccttcc cttttaacct catttgaggc
     5881 ccagccacaa gactttggcc tcagcatcta ggagctgtcc tgcggtccct atcacctacg
     5941 acaaaagagg gacattggct atcaagccaa gactaaatcc ctgtgaagcc agctgctatc
     6001 agattattgt tcaccataga gaatgcctgc agctgctaga tctctcttga tctcttcaaa
     6061 tgcctcctga tcagggcagg acaaaaggtg agtgtgcaga ccctctgtca aagacgacaa
     6121 taattctgcc ttagaggctc cgagcttttc aataaagtta ttgatatcag ctgagctttt
     6181 aatgttaagc ggtgctgtca gcatgccata aatagggtgc tctacctcca cattggtcac
     6241 aatgccatca tgtgctaata tcaactccaa ctcctgcctt gtctgctcag gtccatgctg
     6301 gcaaacaatt ctagcagaat agtgatgact aaacaaagca tttgacagga tatatccctt
     6361 tggtgttgaa ataatgtcaa gctgctgcgc cctaagtaag gcaatgtctc cgacaatcac
     6421 ctgacgacta actcccaatg ccttggctaa gctagttgct gagatggctt cttgtgcttg
     6481 gcttaaccta tctgtaatag cttctcggcg ttcctttact ttcataagat tcccttcttt
     6541 taccactttt taactatcat atcacatttc tgttggaaac gcctttttta tcacataaca
     6601 aaaaaagcca gagctaggtc tggcctcaca gcattattca ccaccgaggt agtactcagc
     6661 agtaagattt agcttgtcat caaattcaaa cacaagcggt gggaagttcg ggatttccac
     6721 attcataatc tcgtcatctg ataattgctt gatgtgtttg acaagggcac gaatagagtt
     6781 accatgtgct ccaacaaaaa catttttacc atcaactaag gctggtgcaa tcttatcttc
     6841 ccagaaagga agggcacgct ctagtgttac cttcaggttt tctgcatctg gaataacaga
     6901 atgatcaaga tgagcgtaac gacgatcagt atgtgctgaa tgctcatcat ctttagccat
     6961 atcaggaggc aacacatcgt atgaacggcg ccagatatga acctgctcat caccaaattg
     7021 ctcagctgct tctgccttgt ttttaccagt caagccacca tagtgacgct cgttcaagcg
     7081 ccatgatttt tcaacaggta cccaaagctg atcagaatac tcaagtgcaa gattagttgt
     7141 cttgatagca cgcttaagca cagatgtaaa ggcaagatca aatgcaatac cagcttcctt
     7201 gatcaatttt ccagcatcaa tagcctgctg tgttcccttt tcggacaaat caacgtcagc
     7261 ccaaccagtg aaaaggtttg ctttgttcca ttctgactca ccatgacgag cgaaaaccaa
     7321 ttttaccatt agttaatatc tccttattaa gtttaaaggc ttcttgcctt tttacaactc
     7381 ctattttaca aaaaataggt caaaaaagct agtctattcc tctctttatt gaaaatcatt
     7441 ttgttaatat catgaaaaac gctaaaacct cacaaaagaa agccttcaag caagtatttt
     7501 gcaaaaatgc cttgctattc tcatgcccta gtgatagaat agaaaaaatt tgtctaaaaa
     7561 tggaggaaaa catggtttct actgccacaa aaatcgctac atttgccttt aataattgcc
     7621 tgatgaacgc tgctggagtg tattgcatga ccaaggaaga gctgctagcc attgaggcct
     7681 ctgaggctgg gtcctttgtg acaaaaacag gtactctagc ccctcgacag ggcaaccctg
     7741 agcctcgcta tgcagataca gcacttggct caatcaattc aatgggactt cctaatcatg
     7801 gctaccagta ttatttagat attgtcacag aaatgcaaaa ggatcaagca agcaagcacc
     7861 actttttatc tgttgtgggc atgtctgctg aagaaaccga gactatccta aaagctattc
     7921 aggcctctga ttatcaagga cttgtcgagc taaacctgtc gtgccctaat gtcccaggta
     7981 agcctcagct ggcctatgac tttgaagcca cagatcagct cctaaaaaag atcttttcct
     8041 attacaccaa gcctctaggc atcaagctac ctccttattt tgatattgtc cattttgacc
     8101 aagccgcagc cattttcaat caatacccct tagcctttgc caactgtgtt aattccattg
     8161 gcaatggctt ggttattgat gatgagcagg tcgtcatcaa gcctaaaaac ggctttggtg
     8221 gtattggtgg tgattacatc aagccaactg ccctggctaa tgttcatgcc ttttaccaac
     8281 ggcttaactc ttctattcag atcattggca caggcggtgt caaaacagga cgtgatgcct
     8341 ttgagcatat cctatgcggc gcagctatgg tacaaattgg aacagcactg caccaggaag
     8401 gtccagctat ttttaagcgt atcactaagg agctacaaga cattatggct gaaaagggct
     8461 accagacact agacgatttt cgtggtcaat tacaatataa gccttaaaaa aagtctgaga
     8521 cgaaaggtct cagacttttt ctagctttat gttaaaaggg aaaggctttt tttgactcct
     8581 cttggtcaat cgcctgcttg gtttcttttt gatcctgttc tagcttcttt agttgttttt
     8641 tctcaaatgc tttataaaag catagaaaaa taatgacctt aaccaccgaa aagatagcaa
     8701 gtccaaggat aacaattatt ggcatatctc tactttcatt tttaatgttc tcactgctat
     8761 tataagctct ttttcccttt caagcaagct ttaatagcag caggtcacga cgcaggcatg
     8821 aagaaaatac atgtacccat tttccagcta caggcattgt tcaacatatt tttagcatgt
     8881 ttacagtgtc acatcatcag tttcttaatt ttaatctgat gatcccgtac aaatgttgcg
     8941 aaaaagacta catcaatgat aaaaatagct atcaaaaagt gtaaatgttt tcatgccttt
     9001 gtggcggcag cagacaagtt tcaaggtttg cacatacggg aaaatacagc aacagaagcc
     9061 ttacatgata tactcattag aggaggaaaa aatatgacta atcatcagtt gggaaaagca
     9121 tttcgcagca ttagacaaaa cagaaatatc accttacagc agcttgccag taaagacgtg
     9181 tccttgtctc agttatcccg ctttgaacgc ggcgaatctg atctatcagt aacaaagttt
     9241 ttaacagctt tagacagcat gcaagtggaa atcagcgaat ttatggacat agctgccaac
     9301 ttcaaacaga cagagcaaat tcaattcatg tcgcagctga tcaagctgga atatgcacgc
     9361 gatattgagg gattcaagca gctgcaaaag caggaattgg caaagcacca agctgatcct
     9421 gataccaatc gttactattt aaacagcatt ctactccaag gctttatctg taaatgcaat
     9481 cctagcattc cttttcctaa ggcttatctt gatgaggtca ctgactacct ttttaggact
     9541 gaaagctggc atatctatga gctgatttta attggaaatc tctatctttt tattgatatt
     9601 cccttattag ataaaatggg aaaggaaatt ctaaacaatc atacctacta cgaaagcatt
     9661 tcaaccaata agcatttggt taccatcacc cttctcaata tttgggaaac ctgtatccac
     9721 cgacatcagc ttgactatgc gcgctattat caaaagcaga tactagccct actcaataat
     9781 gaaaccaagc tatatgaaaa aaccatcttt ttatttttaa agggcttaga ggactaccaa
     9841 agaggacagt gtttgtctgg cattaaggat atgactactg ctatttccat ttttgagagc
     9901 ctggattgtc ctcacctagc gcacaattac caaaaggatt ttgaaagatt tgtagcctcc
     9961 tctagcctta tttgcaaaaa aacataagac cctaaaaaac tgatttataa taaaaccaca
    10021 taatcttttg gaggttttat catgcgcaaa aacgactacc agctgctcgc aagtcgagct
    10081 attaacaaaa taggcaatac tgtttacgac tacagcaaca gcagcgggat tgctggactc
    10141 ggagcaactg gccgacaata tttgggttat tatcagctag ctgaaggcct tatttcactc
    10201 atcttaaatc ctatcggtgg cgccattgct gatcgttata aacgacgaca attgttattg
    10261 tggacagatg ctatcggagc tatcagctgc ggacttttag ccctgatagc taaccctact
    10321 atcatgcttt atgggcttat cactgttaat gctcttttag caatatcgta tgccttctct
    10381 ggaactgctt ttcgagccta tgtggtcaca ctagttgaaa cagaaagact tgttcatttc
    10441 aatgctcagc tagaaatcgt atctcaaatc atcagtattt cctcaccaat gcttgctttt
    10501 ttagtgatgg attgctttgg catcaaaaca gccttggctc tagatagcat tagctttcta
    10561 ttgtcctttc tatgtctata tacaatcaag gacaaagaaa ggcacatcac taaacagagc
    10621 agccaaggca ataggcttca gcttttaaca gatattaagg aggggctgca attcatctac
    10681 catgacaatg acattttttc tttgttgatt attgcttctc ttgtgaattt ctttattgct
    10741 gctttcaatt atttaattcc tttttcgaat cagctgctag gcagccaatc aagctatgct
    10801 agtcttcttt cgatgggagc tttaggggct atcttaggag cttttatggc taacaagctc
    10861 tttaaaaata atcagcaaag cttactccta tccctaggcc ttagtggcct agggatgctt
    10921 ctaataacag ctatggctct cttgaagctt ccagtcattg tgattgccct tgggaattta
    10981 tggtttgaat gctttttaac aatctttaac attcacttct tttctatcgt tcaaaaaaaa
    11041 gttcctgagg cattgctagg acgagtcttt agctcaatcg tcacaactgc tattctctta
    11101 atgccactgg caactaccat catgacctgt ataccagcct ctgttcatct agcaaccttt
    11161 gctgttattg gaataggtat catggcgact gccagtcttg cctactattg taactatagg
    11221 caatcctcca agaaaaagcc cttcatctga gttagtcatt ggtgttagaa atcccttgta
    11281 acattatctc agaaaaaaat caaatagctt gtcatctgag cttaactaat atataata
//
LOCUS       DARYXS010000066        11301 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.067, whole genome shotgun sequence.
ACCESSION   DARYXS010000066 DARYXS010000000
VERSION     DARYXS010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11301
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.067"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(72..2753)
                     /locus_tag="TV193_001424"
     CDS             complement(72..2753)
                     /locus_tag="TV193_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEL1513607.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLESSRKGLTSTEAQQRLAAYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILVAAAFLSVVTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARVRRDGHVIEVDSKELVPGDIVLLEAGDVVPADMR
                     LLEVNSLKIEEAALTGESVPVEKDLSREVSADAGIGDRVNMGYQNSNVTYGRGMGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQR
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQESSADIAFDNNTLRVMNFANDTKVDPAGKLIGDP
                     TETALVQFGLDHRFDVREALVSEPRVAELPFDSDRKLMSTIHKQADGRYFIAVKGAPD
                     QLLKRVTQIEENGDIRPITEADKQTILATNKDLAKQALRVLMMAYKYTEVIPVLETEV
                     VEAELIFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAEAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEAFQKVFRQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRQSSFFDGGVKEAILYQGALQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNKFFHVTH
                     LTLTQWLVVIVGSLLMVVLVELVKAIQRSLGQDDKAI"
     gene            complement(3101..3487)
                     /locus_tag="TV193_001425"
     CDS             complement(3101..3487)
                     /locus_tag="TV193_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEL1513608.1"
                     /translation="MKIEINNKISYGQETELIKEIHTGDLRQKADATYLIYQNNNNER
                     VVIKFNAAELTMSRFSKPQSVMRFLANKKALIAIPTPVGIQQFLTDTSHFHLDHGQQT
                     VTLDYALLQPSTETAFAHYHLEIKWY"
     gene            3568..4869
                     /locus_tag="TV193_001426"
     CDS             3568..4869
                     /locus_tag="TV193_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1513609.1"
                     /translation="MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYS
                     HTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLAD
                     YLCLDDGVLNTYFQQWITSEDHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVE
                     SVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTG
                     TSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN"
     gene            5094..5903
                     /gene="yidA"
                     /locus_tag="TV193_001427"
     CDS             5094..5903
                     /gene="yidA"
                     /locus_tag="TV193_001427"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEL1513610.1"
                     /translation="MSIKLVAIDIDGTLLTDDRRVTNDVFDAIQEAKAQGVHIVIATG
                     RPITGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRR
                     LGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIVKMMMIDEPN
                     LLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAIGHLAKKLGIDMSQTMAIG
                     DAENDRAMLEAVANPVVMENGAPELKKLAKYITKSNNDSGVAHAIRKWVLN"
     gene            5903..7117
                     /locus_tag="TV193_001428"
     CDS             5903..7117
                     /locus_tag="TV193_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEL1513611.1"
                     /translation="MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIG
                     FYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRAL
                     MIKYDPSLFISQALIGEERKDNDFTLSIIDFLKTIGVEWTGRTKELEQTIQPRFQANI
                     YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGIS
                     YYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKVAENQNT
                     IKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWY
                     HTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMI
                     AYNLRKKLRSNP"
     gene            7117..8352
                     /locus_tag="TV193_001429"
     CDS             7117..8352
                     /locus_tag="TV193_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1513612.1"
                     /translation="MALDIIDKETFGSFCSQMKYKSFIQSIEMAELLQKRGYQTQYLA
                     ISDQKNIKIAAILYSIPMTGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELV
                     IKPYDTYQTFTSDGHPNDDEKPELIKTLTELNFTHDGLLTGYHNGEGDWHYVKDLSGL
                     TSANVINSFSKKGKALLKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKSLSY
                     YQDFYDSFGDSCEFMVATLNFDDYLTNLEHSQDKLKQRISKLEADLVKKPKSEKKQNQ
                     LRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRF
                     YAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYY
                     PKPFKYKAIQAIKTMLGRS"
     gene            complement(8561..9319)
                     /locus_tag="TV193_001430"
     CDS             complement(8561..9319)
                     /locus_tag="TV193_001430"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEL1513613.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVKAVVSKLPSNDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLADMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIICCGESLETYEAGKAVAFVGAQVSAALEGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NIKEYMACPDVDGALVGGASLEADSFLALLDFVN"
     gene            complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TV193_001431"
     CDS             complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TV193_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEL1513614.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
BASE COUNT         3394 a         2573 c         2251 g         3083 t
ORIGIN      
        1 ttatttttta actatgaacg tcagaccttt ttgttagttt gaaagtgttc ttatcttttt
       61 gctaatgacg cttaaatcgc tttgtcatct tgaccaagtg agcgctgaat agccttgaca
      121 agctcaacaa gcacaaccat caagagactt ccaacaataa caactagcca ttgtgtaagg
      181 gtcaaatgag tcacatgaaa gaatttgtta aagccaggga caacaactgt agccatcaag
      241 gcaacaaagg ctactgggat agaatagtta aataatttat tcttaaataa tccaactgta
      301 aagatagact gataaacgga cttaacatta taagcatgca ccagctgaat gagaccaagt
      361 gttacataag ccatcgttaa agcatcggca tgcacgtcat ggtagcttgt atgctctggg
      421 aacatcaagg caaagccata aacaccaagc actaggattg tctgaagggc accctgatac
      481 agaatagctt cttttacacc accgtcaaag aagcttgatt ggcgtccacg aggcttgtgc
      541 ttcatgacac caggctcagc aggctcaaca ccaagagcga tcgctggcag cgtatctgtt
      601 accagattaa tccaaagcag gtgaaccggc tgaagcacgt cccagccaaa taaggtagca
      661 agaaagatcg taaagacctc agccatgttg gcagaaagca ggtactgaat tgttttttga
      721 atgtttgaaa agaccttacg tccttcttca acggcaacaa taatagttgc aaagttatca
      781 tcggcaagga ccatatcaga agctccctta gaaacctctg tacctgtaat ccccatacca
      841 ataccaatat cagctgtttt aagagacggc gcatcattga caccatcacc agtcatagca
      901 acaaccttac cttcattttg ccaagcctta acgatacgaa ccttatgctc tggagataca
      961 cgcgcataaa cagaatattg tctaaagacc ttttggaagg cttcgtcaga cagctcattg
     1021 agctcagcac ccgtaaagac atggtcaaca ccatcttctt cgataatgcc aagacgcttg
     1081 gcaatagctt ccgctgtatc ctggtggtca ccagtaatca tgatcggacg aataccagcc
     1141 tccttagcca ccttaacagc ctgagccgct tcagggcgct ctgggtcaat catgccaaca
     1201 agccctgaga aaatcagctc tgcttcgacc acctctgttt caagtactgg aatcacttct
     1261 gtgtatttgt aagccatcat caagacacga agggcttgct tagccaagtc cttattagta
     1321 gccagaatcg tttgcttatc agcctctgta atcggacgaa tatctccatt ttcttcaatt
     1381 tgagtgacac gttttaacag ctggtcagga gcacccttaa cagcgatgaa gtatctgcca
     1441 tcagcttgct tgtgaatggt tgacatcagc ttacggtcag aatcaaatgg taattctgcc
     1501 acacgaggtt ctgaaacaag agcctcacgc acatcaaagc gatgatctaa gccaaattgc
     1561 accaaggcag tctctgtagg atcaccaatc agcttacctg ctggatcaac cttagtatca
     1621 ttggcaaaat tcatcacacg aagggtattg ttgtcaaagg caatatcagc tgatgactct
     1681 tgaagtgccc cgttagtata aaccttttca actgtcatct ggttcatggt caaggtacca
     1741 gttttatctg aggcgataat ttcagttgaa ccaagggttt cgaccgcagg caatttacgg
     1801 ataatagcgt tacgctttgc tagcacctgt gttccaagag aaagcacaac cgtaacaata
     1861 gctggaagcc cctctggaat ggcagcaacc gcaagcgcca ctgatgtcat caagccttca
     1921 agtgggcgct gaccacgtaa aaagacacca actgcaaagg tcacagctgc aatcacaaga
     1981 atagcatagg ttaaaatctt agatagattg tcaaggtttt gctttagcgg tgtgtctgtc
     2041 tcatcagcat tagccagcat gccagcgata tggcctacct cagtgtacat accggtgttt
     2101 gtgacaaccc ccataccgcg tccataggta acgtttgagt tttggtagcc catgttaaca
     2161 cgatcaccaa taccagcatc agcagaaacc tctcttgaca ggtccttttc aactggaact
     2221 gactcaccag taagagcagc ttcctcaatt tttaaggaat tgacctctaa caaacgcata
     2281 tcagctggca ccacatctcc tgcctctagc aggacaatgt cgccagggac aagctcttta
     2341 gagtcaacct caatcacatg accatcacga cgcacacgtg ctaagggact agacatggat
     2401 tttaaggcct caatcgctgc ctctgcctgc ccttcctgat aaaccccgaa ggctgcattt
     2461 aagataacaa cagctaaaat aatgatggca tctgtcaagc cctccatccc ttctgttacc
     2521 acagaaagaa aggccgctgc aaccaaaata ataatcatca aatccttaaa ctgatcaagg
     2581 aatttcatga acaggctgcg cttttcaccc tcgtcaagct cattacgccc ataagctgct
     2641 aggcgctgct gtgcctctgt actcgttagc cccttacgac tagactctaa ttgagctaat
     2701 actgtttctt cactttgcgt atagaacgct tcatgtcttt gttctttcga caaattggtc
     2761 cctccttggt ctttttatgc tttattcaac taaaaagacc tgtttatttt tcttaaacaa
     2821 gtctcgctgt ttcagattgt accggaaatc gaaattccgt attgacgaca caatcacggc
     2881 taaccgtctg ctactccctt gatatagtca ctattataat aaaatgatga ccaaaaaaca
     2941 agaaaaaaac aaggaaatat tttttaaaag ccccaaatca tctgatgatt ttcagagcaa
     3001 aggtaactga tgaccaagct tagactatca ttaccgagat acagacagca gacacaggct
     3061 gtcatcttag gagactaaca aaggacttcc tctgctgaga tcaataccac ttgatctcca
     3121 aatgataatg agcaaaggcc gtctcagtgc tgggctgtaa taaagcataa tctagggtca
     3181 ctgtctgctg gccatgatcc aagtgaaaat ggctcgtatc tgtcaaaaat tgctggatcc
     3241 ctacaggcgt cggaatagcg atcaaggctt ttttgttagc aagaaacctc atcacagact
     3301 gaggctttga aaagcgactc atcgttagct cagcagcatt gaacttaatc actacccttt
     3361 cgttgttatt attttgataa attagatagg tagcatctgc cttttgtctc aaatccccag
     3421 tatgaatctc cttgattagc tctgtttcct gaccatagct gatcttgtta ttaatttcaa
     3481 tcttcatgat atcttctttc tcttgagttt tgctcgtcta ttctaccaat ttctgaccat
     3541 tttcgcaatt tctgctataa tagaagcatg aatgaaaaag tatttcgtga ccctgttcac
     3601 aactatatcc acgttaatca tcagctcatt tacgagctaa tcaataccaa ggaatttcaa
     3661 cgactaaggc gaattaagca ggtgccaaca acagccttta cctttcatgg tgccgagcat
     3721 agccgctttt cacactgtct tggtgtctat gagattgctc gccgtgtcac agagattttt
     3781 gaagaaaagt atgcagacct ttggcataag gaggagagtc ttgtaaccat gactgctgcg
     3841 ctcctgcatg atattggcca tggtgcttac tcgcacacct ttgagaccct atttgatact
     3901 gatcacgaag ctgttactca agatatcatt accagtccag aaacggaaat taatgcgatt
     3961 ttgacgcgct actctcctga ttttcctgac aaggtagcta gtgttatcaa ccacacttac
     4021 cccaataaac aggtagtgca gctgatctct agtcaaatcg actgcgatcg catggattat
     4081 ctgctgcgcg actcttactt ttctgcggct aattatgggc aatttgacct aatgcgcatt
     4141 cttagggtta ttcgacctgt gaaagatggc atagcttttg atctcagcgg tatgcatgcc
     4201 gtagaggatt acattgtcag ccgctttcaa atgtatatgc aggtttattt tcaccctgcc
     4261 agtcgagccg tcgagctgat cctacaaaac ttgctgaagc gtgctaaggc tctctatcct
     4321 agccagcagg actatttcca aaagacagcc cctggtctca ttccattttt tgaaaaaagt
     4381 ttcacgcttg ctgattatct ttgcttagat gatggtgtgc tcaataccta tttccagcaa
     4441 tggattacta gtgaggacca tatcctgtca gacctgtcta gtcggtttat caatcgaaaa
     4501 attttaaaat ctgtcacctt tgaccaagaa tcacaacagg atttagagcg cttgcgaaag
     4561 cttgttgagt cagttggttt tgatcctgat tattatacag gtatccatgt caattttgac
     4621 cttccttatg atatttaccg tcctgagctg gaaaatccaa gaacccaaat tgaaatgatt
     4681 caaaaagatg gcagcagggc tgagctatcc cagctctctg cgattgtcaa agctctcaca
     4741 ggcacaagct atggtgatag acgcttttat ttcccaaagg aaatgttaga gcttgatgac
     4801 ctctttacat cagataagga agcctttatc agctatatct ctaacggaca ctttcatttt
     4861 aacaactaag gaccagccaa ggtccttttg gctttttcat cacgctctag atttaaaatg
     4921 gtatattacc cgataaggac agctagagct ctgacaagca caagccacca aacacagcag
     4981 agcctttaat attgccaaaa tctcttttgt tttcatgaca aaagaaccta tttttagtaa
     5041 gatagaaggt ggcaaatcat tgattacaaa tcagaacaac caaggagaat tccatgtcta
     5101 tcaaacttgt tgccattgat attgatggca ccttactcac tgacgatcga cgcgttacta
     5161 atgacgtttt tgatgccata caggaggcca aggcccaagg agtgcatatc gtcattgcta
     5221 cgggacgtcc cattactggg gtcatctcat tattagagca attgcaatta aatcaaaagg
     5281 gagatcatgt catcaccttc aatggtggac tgattcagga cactgcaacc ggtgaagagg
     5341 tggttaaaga gctgatgacc tacgatgatt acctcgacat agaatattta agccgcaggc
     5401 taggcgttca catgcatgcc atcacaacag agggcatcta tactgctaac cgaaatatcg
     5461 gcaaatacac tgtacgagaa gcaaggcttg tggacatgcc tgttttttat cgaacacctg
     5521 aggagatggc tgacaaagag atcgtcaaaa tgatgatgat tgatgagcca aaccttttag
     5581 atgaggccat caaacagatt cctcaagcct tctatgacac ctacaatatt gtcaaatcaa
     5641 caccttttta tctcgaatta acaccaaaaa ctgtcagcaa gggcactgct attggtcacc
     5701 ttgccaaaaa gcttggcatt gacatgtccc aaacgatggc aatcggcgat gctgaaaacg
     5761 atcgagccat gcttgaagcg gttgctaacc ctgttgtcat ggaaaatggg gctcccgagc
     5821 tgaaaaagct ggccaaatac atcaccaaat caaacaatga cagcggcgta gcgcatgcta
     5881 ttcggaagtg ggtattaaac taatgtatac atataaaatc ggaatttcag ctaaagagca
     5941 cgatcagttt gtcctatcac atcctcaggt caatctgctg caaagcgctc attgggctca
     6001 ggtaaaggat aactgggagc atgagctcat tggtttttac caggatgaca agcaagtcgc
     6061 tgctgctgct tgccttatca agagactccc cctaggcatg accatgattt acattcctcg
     6121 agggccgatt atggattatt ctgactttga gttggttaac ttcgtcatga ctagcctaaa
     6181 ggcttatggt aaatccaagc gagctctcat gattaaatac gatccttcct tgtttatcag
     6241 tcaggcctta ataggtgaag aaagaaagga caatgacttc accctctcca ttattgattt
     6301 tttaaagacc atcggtgttg aatggactgg caggaccaag gagcttgagc aaacgattca
     6361 gccccgcttt caggccaaca tttacgccaa ggactttaag ctccaaagct tatcaaaaaa
     6421 agccagacag tctatccgaa ctgctcaaaa taagggagtc gagattatta ttggctcaac
     6481 agagctactt gaagacttct cagcactgat gaaaaagact gaggagcgaa aacacatttc
     6541 tttgcgtggc atttcctatt atgacaaatt aatgaccact tacgctaatc aggcttacat
     6601 taccatggct agattgaacc ttcccaagca aaaagcgctc atacagcagc aattagagga
     6661 agccttgagc aatcagcagg cctttaccca gcacagtaag ccaggtaagg tcgcagaaaa
     6721 ccaaaatacc attaaaaggc ttgaaaagga attggctttt ctagataagg aaatacaagc
     6781 aggtaaaagc cttgtacctc tagcagctac cctgacactg atctatggac agacctctga
     6841 aaacctatac gcaggtatgg ataatgactt tcgccaatat caggcagccc tcttaacctg
     6901 gtatcatacc gcagaagagg cctttaagcg cggttgtcaa tggcacaatt tagggggcgt
     6961 tgaaaaccaa ttagatggtg ggctgtttca gtttaaagca agactaaacc cagctatcga
     7021 agaatttgca ggagaattca gcattccagt tggacctatc tcaaaggtgg ccatgatagc
     7081 ctacaatttg agaaaaaaac taaggagtaa cccttaatgg ctttagatat cattgacaaa
     7141 gaaacgtttg gctcattttg cagtcaaatg aagtataaat ccttcattca atctatagaa
     7201 atggcagagc tgctgcaaaa gcgtggttat cagacacaat accttgcaat cagtgaccag
     7261 aaaaacatta agattgcagc cattctctac agtataccaa tgaccggcgg cttacgcatg
     7321 gaaatcaact caggtccagt agtggctgat acgacctaca caacagcctt ttacaaagcc
     7381 ttacaggact atgccaagca gcagggagca cttgagctag tcatcaagcc ctacgatacc
     7441 tatcagacct ttaccagcga tggtcaccca aacgatgatg aaaagccaga gctgatcaag
     7501 accttgacag agctcaattt tacacatgat ggcctgctaa caggctacca taatggtgaa
     7561 ggagattggc attatgttaa agatttaagc ggattgacct ctgctaatgt catcaattcc
     7621 ttcagtaaaa agggcaaggc cctgctaaaa aaagccaaaa cctttggcat taagctacat
     7681 aagctcaatc gtgatgagct aacacaattc aaggaaatta ctgctgctac atctagtcga
     7741 agagattata ccgacaagtc tttatcttat tatcaggatt tctatgatag ctttggggat
     7801 agctgtgaat ttatggttgc aaccctcaat tttgatgact acctgaccaa tctagagcac
     7861 agtcaagaca agctaaagca gcgcattagc aaattagagg cagacctagt taaaaaacca
     7921 aaatcagaaa aaaaacaaaa tcaactacgg gaactctcca gccaatttga tacctttcaa
     7981 gttcggatag ctgaagcaca ggagttaatt gtcaagtatg gcaaaaagga cattcctcta
     8041 gctggtagtc tctttgttta caccccgcag gaggctgtct atctcttttc tggctcctat
     8101 ccagaattta acaggttcta cgcgccagcc ctattacagg aacatgtcat gctaagagcg
     8161 attgaaaaga aaatcagctg ctataatttt cttggtatca tgggcgaatt tgatggctct
     8221 gatggtgttt tacgctttaa gcaaaacttt aacggctata tcacacgaaa gatgggaacc
     8281 tttaggtatt atccaaagcc cttcaagtac aaagccatac aggccatcaa gacaatgctt
     8341 ggtcgcagct aagtcaagct agtggctaag cagcccttta agccttccaa tggctattga
     8401 ccacaataat aaatccttga ttgtcttact cagaacccct ttagtaaact ttccaaccta
     8461 aaaataaggt ataggtgatc ccatgctcaa gaaggctatc aagcaaacca aaagctcaag
     8521 gaattaaccc ttgagctttt tagctatatt ataattgtca ttagttgaca aaatcaagca
     8581 aggcaaggaa gctatctgct tctagtgatg caccaccgac aagagctccg tcaacatccg
     8641 gacaagccat gtactcctta atgttttcag gcttcacaga accaccatac tgtacacgaa
     8701 ccttgtctgc cacctcttga ccaaagtcag cagcaaccac atcgcgaaca gccttacaca
     8761 tgctttgagc atcttcttga gtggcagatt taccagtacc gatagcccag attggctcat
     8821 atgccaatac caatgaagca acctgctcag cagatagccc ctctagagcc gcagacacct
     8881 gtgcaccaac aaaggctact gccttgccag cctcataggt ctcaagagac tcaccgcagc
     8941 agataattgg tgttaagcca ttagcaaaga tggcttttgc ttttttatta atatcttcgt
     9001 ctgtttcgtg gaagtaatca cgacgctcag agtgaccaat caccacataa tcagctccca
     9061 tgtcagcaag aaccttagga gaggtttcgc ctgtataagc gcctgaattt tcaaaataac
     9121 agttttgcgc agcaacctta aggacagagt ccttagcagc ctcaattgta gtgaccaagt
     9181 caacagctgg tgctgctact gcaacgtcaa caagatcgtt tgaaggtaat ttgcttacta
     9241 ctgccttaac aaaggctttt gcctcttgag gatttttgtt cattttccag ttaccggcaa
     9301 taattggttt acgtgacatt tcacatacct cttctttttt tatttacatc tactattcta
     9361 gcacaatttc tatgctaata aaagaaaatg gctgactttt aggaatattt tcacaaagaa
     9421 aagagtattt tctgaaacca ttttcaaacg ataaggctta tcgattagct aagcagaccc
     9481 gctaagtcct catctttata aacagagcaa aaagagccct taaaacaagg gctctcacaa
     9541 ttaagctgtc tgactttaat cgttatctgg gaacttaatc aaaattaagc ttcgatttct
     9601 gaaacgatac ctgaaccaac agtacgtcca ccttcacgaa ttgagaatgt agtaccttgt
     9661 tctacggcga ttgggtggat caactcaacg tcaatagtca cgttatcacc aggcataacc
     9721 atttctgtac ctgctggaag ctcgattgaa cctgttacgt cagtagtacg gaagtagaat
     9781 tgtggacgat agttgttgaa gaatggtgtg tgacgtccac cttcttcttt agtaaggata
     9841 tatacttcac ctttaaattt agtgtgtggg ttgatagaac ctggcttagc aataacttga
     9901 ccacgttcga tttcatcacg ttgtacacca cgaagaagaa caccaacgtt gtcccctgca
     9961 agaccttcgt caagctgttt acggaacatt tcgacaccag taacaactgc ttttttgatc
    10021 tcgtctctga taccaacgat ttcgatttcg tcgttaacac gaacagtacc gcggtcgata
    10081 cgtcctgaag caacagtacc acgtccagtg attgagaata cgtcctcgac tggaagaagc
    10141 aatggcttgt ctgtgtcacg ttctggttct ggaatgtatg aatcaacagt atccatcaat
    10201 tccatgatga tatcttcgta tttgctgtcg ccttcaagag ccttaagcgc tgaaccttgg
    10261 ataactggaa ggtcatcacc tgggaaatca tattctgaaa gaaggtcacg aatttccatt
    10321 tcaacaagct caagcaattc ttcatcgtca acaaggtcaa ccttgttcat gaacacgata
    10381 aggtgcttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg tggcattggt
    10441 ccgtcagttg aagcaactac aaggatagct ccgtccattt gagcggcacc agtgatcatg
    10501 tttttaacgt agtccgcgtg tcctggtgcg tcgatgtgcg catagtgacg tgtagcagtt
    10561 tcgtactcaa cgtgtgcagt gttgatagtg attccgcgtt cgcgttcttc tggagcagca
    10621 tcgattgaag cgtagtcttt tggttggtta actgagcttg gtagacgacg tgcaagaaca
    10681 gttgtgattg cagctgttaa agtagtttta ccatggtcaa cgtgtccaat tgtaccaatg
    10741 ttaacgtggg gtttactacg atcgtatttt tcttttgcca ttttaggaaa agcctccaat
    10801 aaaatatatt ttatagatag acggtaggca atacagtcta actttacctt actattgtag
    10861 caaattataa ggaaattgca agcagtaagt gaggaacttt aacggattta tcgttatccc
    10921 tgatttcaac aaccctagca tacaaaaaag gaaagagttt tcgtcttctc ccaggcaatc
    10981 cgctctttac cgttttttgc ttttcaaggc tctaggcatt tgcatacttt tggaggagag
    11041 ttgaattgtt aagagataat gcattcggag atctataaat cataggcagg acataccgat
    11101 ccaaaactaa gatagtggag acttgatggt ccatgacaga cgcgcgaaac agctatttcc
    11161 gaatgataat atagatgaga gtagacactt tcaacgttct tcctatagta aaagctatgc
    11221 aaaatcctac atattcttga aatagctgaa cattgaaata caggaagctt tattttattg
    11281 ctaaaaatct ttcatgtgtc t
//
LOCUS       DARYXS010000067        10982 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.068, whole genome shotgun sequence.
ACCESSION   DARYXS010000067 DARYXS010000000
VERSION     DARYXS010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10982
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.068"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..772
                     /locus_tag="TV193_001432"
     CDS             <1..772
                     /locus_tag="TV193_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1513615.1"
                     /translation="KIYIEENGKDGYYLYIYEDTNKNDKYDKNKDKLLQKKYIKNGKD
                     GKPGLNGQRGPQGEPGKQGPQGPRGDKGETGEKGQDGKPGKQGDRGPAGPQGPRGDKG
                     ETGEKGDPGRNGKDGKPGEKGDPGQQGIPGPKGDPGKDGEKGERGEQGPQGERGEQGP
                     RGENPTPTPDPMPQPMPDPAPKPESKPEPKPIPQPEVKPQPETKPQQPNKPSTITSQP
                     SGKALPKTNDTGSLITVLGTGLLSLLGLGFLTRRKRKQ"
     gene            1089..2384
                     /locus_tag="TV193_001433"
     CDS             1089..2384
                     /locus_tag="TV193_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1513616.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGAARVLAEQYYGYDDGTKDG
                     GDWPVFLYVTPTNHPERKTDKEHCVYCFNRLNSSPELWESQFKDPSKLGIKLPIYEKK
                     EGDESLLRAKSQKPSDNLTSKLVTVLSNGYPNKTLGNLSEDQSRRLTQLAIWHFTDGY
                     ATNHFKDGYHLNKDEDSELKKLIETAEKNFQTTAHTYSLNLYVTSSYNYSTGKFYQHL
                     LGSTLTPKLPNPNPGPKPPGGNNPHHLPGENGQTKYPEGESGEAGAPKKPEPKPEPKP
                     EPMPKPEPKPQPEPMPEPKPDPQPKPEPKPQPEPKPEPKPQPVPKPDPEPMPDPEPKP
                     QPEPKPEPQPEPMPKPEPKPQPEPMPEPKPKPEPQPKPAPQPEVKPQKPTKPSNTTSQ
                     SSGKGLPRTNEAGSLMTGLGTGLLSLLGLGFLTRRKRKD"
     gene            complement(2517..3635)
                     /locus_tag="TV193_001434"
     CDS             complement(2517..3635)
                     /locus_tag="TV193_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513617.1"
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQA
                     KIGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEEKAIDQYLKAKTLEAVLTIEPGFGE
                     KVLKGDTQKIALRSIADSQITEWFKAQANYLLENYNIIGDAAAGNQEVFKKISAHNTK
                     LSYKVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSR
                     LSSLQYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFG
                     LMIGAVSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHWVLTIIS
                     TFQNGGNLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(3632..4759)
                     /locus_tag="TV193_001435"
     CDS             complement(3632..4759)
                     /locus_tag="TV193_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513618.1"
                     /translation="MILFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFN
                     TAATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKDIAKAKQKVSEGAL
                     TAALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIANLYPEAISNIKKR
                     KIDYIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTG
                     VSNSAILLGKLIGGMLATAVQLTILYVFTRFVLRVNWGTNDWQIIGVTASLVYLSVAI
                     GIGLATGIRNQSFLTVASNAVIPVFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDS
                     LFYLIFGGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            complement(4768..5691)
                     /locus_tag="TV193_001436"
     CDS             complement(4768..5691)
                     /locus_tag="TV193_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513619.1"
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKS
                     TLINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGSELKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNEQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQ
                     AELERRYESDFTKQIMVTVAADQAIDLSNKPNWRLMDNELEAVLLIEHEDIGSVVRQL
                     TDAHIAFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            complement(5714..6400)
                     /locus_tag="TV193_001437"
     CDS             complement(5714..6400)
                     /locus_tag="TV193_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEL1513620.1"
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAMSYQQWLD
                     LLLGLIQLGLVLVCLLFSDALALDGLLTFLGRVSFGWEIICYVLLYSIALVELTLLVL
                     VLLFDLMLKKDSRLLLGKMTWLAFKPDRAAASFLLLSLVTLVDAFCYLGLCLFLGKDS
                     VAGLTLVVLGYALVKACRYSGWLQQLLALCLFSVIGVWCVTAALLYGWLIGSLLLTLT
                     YLLISFKEQR"
     gene            complement(6397..7068)
                     /locus_tag="TV193_001438"
     CDS             complement(6397..7068)
                     /locus_tag="TV193_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1513621.1"
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRA
                     VLVYYALVLTGIYLLSPPIKAPLGHSDGRLLIIGFILSFVVLFVEVAFLHLSRCWQKK
                     EWLPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSL
                     CYALNHFLMGRSIFYAKILTGLIYGSIYYVSQSLWLVLLVHVGGNLWVEGLSHLQSMH
                     KKVVR"
     gene            complement(7043..8401)
                     /locus_tag="TV193_001439"
     CDS             complement(7043..8401)
                     /locus_tag="TV193_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEL1513622.1"
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHPHDVYLKS
                     VTGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRI
                     VYASYKELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFF
                     EDKEMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSM
                     MLSWHTKKPCPRVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILK
                     NKSNEGPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLF
                     LDLDSNVFYYAHPKDQELKWKAFEPLISGEVRLSDLTNHAGKDKKEDLKTLLAYTKKV
                     SPNAVFLDITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            complement(8414..9478)
                     /locus_tag="TV193_001440"
     CDS             complement(8414..9478)
                     /locus_tag="TV193_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEL1513623.1"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEA
                     YYSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMK
                     VLTGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQE
                     TDVTSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLG
                     FVDGPFIHACTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALTKLR
                     YEDQQISTREIVKKLLQEES"
     gene            complement(9475..10425)
                     /locus_tag="TV193_001441"
     CDS             complement(9475..10425)
                     /locus_tag="TV193_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="HEL1513624.1"
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVL
                     KTSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYF
                     EDRANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAII
                     KEGMTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQED
                     IRAFAEYGPITAENCNVILIYVYQYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTAL
                     VYGSVDIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     gene            complement(10653..10817)
                     /locus_tag="TV193_001442"
     CDS             complement(10653..10817)
                     /locus_tag="TV193_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="HEL1513625.1"
                     /translation="MLQFASNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTIN
                     NNYGAAEPKA"
BASE COUNT         3595 a         2437 c         2086 g         2864 t
ORIGIN      
        1 taaaatttat atagaagaaa atggaaaaga tggttattat ctttacatct atgaggatac
       61 gaataaaaac gataaatatg acaaaaacaa agataaacta ctacagaaaa aatacataaa
      121 aaatgggaaa gacggcaagc ctggcctaaa tggtcaacgt gggcctcagg gcgaacctgg
      181 gaaacaagga ccacaaggtc ctagaggtga taaaggggaa accggagaaa aaggacaaga
      241 tggtaaaccg ggcaaacaag gtgatcgtgg tccggctgga cctcaggggc ctagaggtga
      301 caaaggggaa actggagaaa aaggagaccc tggacgtaat ggtaaagacg gtaaaccagg
      361 tgaaaaaggg gatcctgggc aacaaggcat tcctgggcct aagggtgatc ctggaaaaga
      421 tggagaaaaa ggtgaacgtg gagagcaagg acctcaaggc gaacgtgggg agcaaggacc
      481 tcgtggagaa aatcccactc ctaccccaga tccaatgcca caaccaatgc ctgaccctgc
      541 acctaaacca gaatccaagc cagaacctaa gccgatacct caaccagagg ttaagcctca
      601 gccagagaca aaacctcaac aaccaaacaa gccatcaacc attactagcc aacctagcgg
      661 caaagcacta ccaaaaacaa acgacacagg cagcttgata acagtattgg gaacaggctt
      721 gctctctctt cttggactgg gcttcttaac tagacgcaaa agaaaacaat aattaaagca
      781 ctatctatag ctttttaatc attggctatc aaacaaatca caaaaaagct tatcgtttta
      841 ctcctaacga taagcttttt cgtattctct attacttggt cccaatacta tttttccagc
      901 tttaggctgg ttttgttaat ccaaaataat atcagacaat ttccgtttta attaaaaaaa
      961 aaaaaaaaaa cgaaactgcg gaagctaatt atcagaaaat gattcacagc ttagagtcac
     1021 catgttaagc tattctacgg agaagaaagg tttgggaatg actatttcta aactcaaagg
     1081 agagaaacat gagaaaaaca atgaagaaga tgctagcagc ctcgacagtc tgcatcatca
     1141 tgtcgggcag ctttatcgga ggcgcggcaa gagtactggc agagcagtac tatggctatg
     1201 atgatggaac aaaagacggt ggagactggc cagtattttt atatgtaaca ccaacaaatc
     1261 accccgaaag aaaaaccgat aaagagcact gtgtctattg ctttaacagg ttaaatagtt
     1321 cacctgagct ctgggaatct caatttaaag atccaagtaa gctaggtata aaactcccta
     1381 tctatgaaaa gaaagaagga gatgaaagcc ttttaagagc taaatctcag aagcccagtg
     1441 ataacttaac ttcaaaatta gttactgttc tttcaaatgg ctatcctaat aagacattag
     1501 gtaatttaag tgaagatcaa agtcgccgat taacacagct agctatttgg cactttactg
     1561 atggatacgc tacaaatcat ttcaaagatg gttatcatct aaacaaagat gaagattcag
     1621 aattaaaaaa gttaattgaa actgctgaaa aaaacttcca aactacagca catacctata
     1681 gcttaaatct ttatgtaact tcatcatata attatagtac aggtaaattt tatcaacatc
     1741 ttcttggttc cactttaaca ccaaaacttc cgaacccaaa tccaggacct aaaccaccag
     1801 gtgggaacaa tccacatcat ttaccaggtg aaaatggtca aactaaatat ccagaaggag
     1861 aaagcggtga ggcaggagct cctaaaaagc ccgagcctaa accagagcct aagccggaac
     1921 caatgcctaa gccagagcct aagccacaac ctgagcctat gccagaacct aagccagatc
     1981 ctcagcctaa gccagagcct aaaccacaac ctgagcctaa gccagagcct aaaccacaac
     2041 ctgtgcctaa gccagatcct gagcctatgc cagatcctga gcctaagcca caacctgagc
     2101 ctaaaccgga acctcagcca gaaccaatgc ctaagccaga gcctaagcca caacctgagc
     2161 ctatgccaga acctaagcct aaaccggaac ctcagcctaa accagcgcct caaccagagg
     2221 ttaagcctca aaaaccaacc aagccatcaa acactactag ccagtctagc ggcaagggac
     2281 taccaagaac aaatgaagca ggcagtctaa tgacaggact tggaacaggc ttactctctc
     2341 ttctcggatt aggcttccta acaagacgca aaagaaaaga ctaagacact aaaagattat
     2401 ctatagtcgt ttagttgatc agtatctagt ctaatacaac acaaaagcct tatcgcgcca
     2461 taaatggaac gataaggctt tttaagcttg gttcaaaaag ggtaagacaa cttagtctag
     2521 cgatgtaaag gcttcatcag cacgcttgct agtaccatta aggtcatggc tgctacaaac
     2581 aaggccaaga aataaggcca agcctcacct agattaccgc cattttggaa agtgctgatg
     2641 atggttaaca cccaatgttg tgggagtagc tttccaatcg cctgcatata aggcggcgta
     2701 atactaagcg gccacaaaca acccgccagc atagaggttg gcatcacaat cagattagcc
     2761 aattgactgc tttgttgcgc atttttagaa accgcaccaa tcattaagcc aaagcctata
     2821 gctaacaaac tataaagaaa gaaagtcaac aaaacaatgg ctgttggaat gtaaaagctg
     2881 acatttgcta ccctgagtaa tcccagcata atcactattt gtatcgcaaa ggcaacaata
     2941 ccaacacaga catagctcag catgtattga aggcttgata gccttgataa gactaagcga
     3001 ttgtagattt gactggactt atcaagcaag ataccaccgt acaagacact ggtgctgcct
     3061 agcattagga tcaataaaaa gccagttgtt gtcgaggaaa cagacttact ttgggaacga
     3121 tcagctaggg tgatttcttt gaccttgtag gatagcttcg tgttatgagc tgaaatcttc
     3181 ttgaaaacct cttgattgcc tgctgccgca tcaccaatga tattgtaatt ctccaagaga
     3241 taattagcct gcgccttaaa ccattctgtt atttgactat cagcaatcga acgtagagcg
     3301 atcttttgag tgtctccttt tagaaccttc tcaccaaagc ccggctcaat ggtcagcaca
     3361 gcctccagtg tcttggcctt taggtattga tcaatagcct tttcctctag cctagtatat
     3421 atctgatatt ttttattgtg ctttaattgc gacacaaact gcttggaaac ctgactctta
     3481 tccttatcta agatcccaat cttagcttga cttccccctg taaagctcaa ggacaaggcc
     3541 agcattgttg ttagcatagg caacaggata aaggtgatat agcttgtttt tttacgtcta
     3601 attttgataa ataaggcttt aataaaagga atcatgctgc cacctgcttt ctcattctga
     3661 ccaaagcaaa gaggataaag gctgttccta taccaagatt aaccattaag gtaaccggta
     3721 tgggattgga ctgcccacca aaaataagat aaaacaaact atcattgacc cattttatcg
     3781 gggaaatatt agacagctga ttaatcaagg cgctatttaa ggttgacaaa ggaatatagc
     3841 ttcctcccaa aaaggcaaag acaggaatga ctgcattaga cgctaccgtc aaaaaggatt
     3901 gatttctaat accagtcgca agcccgatac cgatggcaac agacaaataa actagcgagg
     3961 ccgtcacacc gataatctgc cagtcattag tcccccaatt aacacgtaac acaaatcggg
     4021 taaagacata aagaatggtt agctggactg ctgttgctag cataccacca attaattttc
     4081 caagcaaaat agcactattt gagacccctg tcaaataaat gcggctagcc accccttgct
     4141 gacgatctga tagcaccaga ttcatcgctg acataatgct ataaaaggta atcatggtaa
     4201 acatggaaat agcatagtaa tccgctgagc tcatgccttt actggtttgc acagagctag
     4261 aggcgatata gtctattttt cttttcttga tgttgctaat ggcttctgga taaaggttag
     4321 caatcgaatc ataggtcttg gcgttatcca catagatatt gacaagcata ttaatcaaat
     4381 cagcattctg ttggttaatg ctgttggtgg tcacctcaat gttttggtcg ctcttaacct
     4441 ctagagctgc cgtcaaggcg ccctcgctga ccttttgctt agccttagcg atatccttgg
     4501 tttctttagc ttctaaatga agctctttat ttaacagctt taaaaacgtg ataaagttct
     4561 tttgatactc tgtttccttg ccctcaagct gataacgaac cgtcaattta ggaacagtag
     4621 ctgctgtatt aaagctggac ttaaaagcaa agcttaaaat cagaatcatc aagataggaa
     4681 aaaccaccat catcaacaaa gcagtccgat ccctaaaaat ctgtaagctt tcttttttga
     4741 ttaaatgaaa taagatcata acaaccccta atctcttagc ttcttaccag tcaaatgcag
     4801 gaagatttct tctaaattca aatgcttatg cctaatctca ctaaaagcaa tatgagcatc
     4861 tgtcagctga cgaacaaccg agccaatgtc ttcatgttca atcaggagaa ctgcttcaag
     4921 ctcgttatcc atcagtctcc aattgggctt attagagaga tcgattgctt ggtcagctgc
     4981 gactgtcacc atgatttgct ttgtgaaatc agactcatag cgtctttcta gctcggcctg
     5041 actgccctct tcaatcacct gaccatgatc cataatgtaa atgtaatcac ataaggcctc
     5101 aacctcttcc atgtagtggg tcgtgtaaat aacagtagct ccttgctcat ttaacaagcg
     5161 aatagactct aaaatatgat tacgagactg tgggtcaatc cctaccgtcg gctcatcaaa
     5221 gatgattagc ttaggagaat gcaccaaagc acaggcaatg tttaaccgtc ttttcatacc
     5281 tcctgaaaac tggcttggaa actggcttgc ctgtgatttt aaccctacga actccaagct
     5341 ttttaaaacc tgctccttga gctcacttcc ctttaagcca tagagagagc cgaaaagctc
     5401 aacattctca taggctgtta aatcaggata aacagcaata tcctgaggga catagccaat
     5461 cttggaacta atttttcgaa tagatttata agattgctgt aaaacagtca cttcgccagc
     5521 attcaaaggg attaacccta aaatagcatt gattaaggtt gacttaccag cgccattagg
     5581 ccctaaaagg ccgtagattc tcccttcctc aattgtcagt gagacatgat ctattgcctt
     5641 tttgccgcct cgatagacct tgacaacatc ttttaactct acaaaactca tatattattc
     5701 cttctttcca actctaacgc tgctctttaa aactaattaa cagataagtt aaggtcaata
     5761 aaagcgaacc aatcaaccaa ccatataata aggctgctgt cacacaccag acaccaatca
     5821 cactaaagag gcatagggct agtagctgct gtagccagcc tgagtaacga caggccttga
     5881 ccaaggcata gcccaaaacc acaagcgtaa gacctgccac tgaatctttt cctaaaaaga
     5941 gacatagacc taagtaacaa aaagcatcaa ccagtgtgac aagacttaac aaaagaaagc
     6001 tagctgctgc cctatctggt ttaaaggcta gccaagtcat ttttcctaag agcaggcgac
     6061 tgtccttttt cagcataaga tcaaaaagca agaccaaaac caacagggtc agctctacca
     6121 aggctatgct atacaatagc acataacaaa tgatttccca gccaaaggat acgcgaccca
     6181 aaaaggtcag caaaccatca agagctaaag catcagaaaa taatagacaa acaagcacta
     6241 gaccaagctg gattagacca agcaatagat caagccattg ctgataggac attgccctga
     6301 tgtgccttaa atgccatctg actaagcgcc gtcttttatg acttgttaga aaaagggtca
     6361 ctaggattaa aaaggatagc aatgctagta ttatgatcat cgtaccacct tcttatgcat
     6421 tgattgaaga tgactcaagc cttcaaccca taaattgcct ccaacatgaa caagcaacac
     6481 cagccataag ctctgactaa cataataaat acttccgtaa ataagaccag tcagtatttt
     6541 ggcgtaaaaa atggatctgc ccatcaggaa atggtttagg gcatagcaca ggctggtgat
     6601 caacaagaca agagcaattg gcaatcgcca ttgaagccac aagatgttaa accaaatcaa
     6661 acgataggtg atttcctcac agcaggccaa aaccaaggga tagcctatct gtggccattt
     6721 ttgtgtcgtt ccgacaaatg ataggactaa gggaagccac tctttttttt gccagcagcg
     6781 gctaagatgt aaaaaagcaa cctcaacaaa gagcacaaca aagctcaaga taaaaccaat
     6841 gatcaaaaga cgaccatcac tatgacctaa gggcgcttta ataggaggtg acagcaggta
     6901 aatccctgtt aagactaggg cataataaac cagtacagct cttaaaaaac ctattagatt
     6961 aaagctatag ctatcacgac cctggccaaa aatagcctgc attgcgatcg aaggacaaaa
     7021 ggtagccatt aaaaagcata ggttaaggca ttgggtgtac aaaggcattt gtcacacctc
     7081 caaactgtct catgcgtgga tgattagcaa atggaaaggc aggaatgcac atctcaagaa
     7141 gctcaggagt gaggacacgt gtcacgtacc agcctttttc tgaggcctca ggaggagtaa
     7201 tgtctaaaaa gacagcatta ggacttactt ttttagtgta ggctagtagt gtctttaaat
     7261 cctctttttt atctttccca gcatggtttg tcaggtcact aagacgaacc tctcctgaaa
     7321 tcaagggctc aaaggccttc catttaagct cctgatcctt tggatgagca tagtaaaaga
     7381 cgttactatc taggtccaaa aacaagggag agtcactctc agcattttgt gttgacgttg
     7441 gattataaaa caaattatag taatagctat agctaatagc tgaagcttcc atgattcctc
     7501 ttaacagggt atgcttagga tccaagcccg cctgaacccc aaataagaga taaggacctt
     7561 cattggactt gtttttaagg ataataccaa aggtataaag cggattatct tctccaacag
     7621 tcatgtcaat agggataatc tcataaagac tgtccttacc aagtctagcc tcttccaaaa
     7681 gagctagaat ttccggatca tcaataatca ctctgggaca aggcttttta gtatgccagc
     7741 taagcatcat agagtcgatt tgaatatact caatcaagct attacacatg gctgcttcca
     7801 gcgttgtatg agaggctgtc cccgttgaaa agcctggaat gatgtgcttt tcgcctacag
     7861 cctgattggt cttatagcca acgcaaagca tttgggcagg cacatacatc tccttatctt
     7921 caaaaaacat cggacactta acccagccca agacatcgtc ttgcgtcacc attttatcac
     7981 acatgatcat gtgcaaatca tggcaacggt caatttgttc ctgcgtaaaa acctgcaaat
     8041 actctaaggg catgacagga tccgtctggc tcaattcctt ataagaagca taaacaatcc
     8101 ggtctgataa taattcccca gcaataacag tggcataacg ctcaatgctt tcacctaagt
     8161 atttgatcaa ggcttcctca taatgactgc cataaccaat gatatgatag ctcacctgac
     8221 tcagctcacc aataaattgc ttgtggtagt caggcatctg tcctgtcaca ctctttaagt
     8281 aaacatcatg aggatggtta caaataggaa cctgagattg atttaagata ccagttcggt
     8341 taccactaag gccctttagc ttatcaagaa tatggttgaa cgaagggtaa taatgtagca
     8401 tccttagacc tccttatgac tcttcttgaa ggagtttttt aacaatctca cgtgttgaaa
     8461 tctgttgatc ctcatacctt aattttgtca gagccccttg tgtctgagaa ttagacattt
     8521 tcaaaatatc ctgcacctga atctcaagcg ttggcaaata gacacttaac aaacgccctt
     8581 caaattttga gcttcctgtt tgagcaataa taaaggcctc actgacaacc agattcatta
     8641 acacatttaa caaaggtaca taagaggagc taacaggctg tgttggcggc aactgctgac
     8701 ttgcaaagcg ctgataaagc gtgtgatcct gtaaacgtgc cagcaccctt ctctccaagc
     8761 tatcaaaatc agcactatga ggaggattta aggtacaagc atggataaac ggcccatcaa
     8821 caaagccaag caccaattgt tttttcaagg ccacactgat ttcattaagg tgacgcagca
     8881 tcataatatt caaccggcct tgacaaataa caatactctg atagtctgcg agcttctcag
     8941 ataagcactt catgttgcga tggtgctcca gagcatctaa gcgagaggta acatctgttt
     9001 cttgaatgag catttttagc tcatcgctag ccacctgaag gtttaagttc aggtgcttgg
     9061 ccagcagctc agcagattca ttgacatagc ttgaatcact gataaataag acaggtgcag
     9121 tatccttagc ctgtcctgat tcagctatga aatgataatt gcctgttaag accttcatga
     9181 tattttcttc aagagcataa gcgtcttcaa gcatcaatag gtcgttataa tacaaggctg
     9241 tgatgacctc tgacaatttt gcaaataagt cagactctag tgttttttcg taggtatcag
     9301 tatcaataac tttcccgtta aaccaatcgg agatgatact gtagtaggct tcttttaagg
     9361 cttgtggctc ttgtgcaatg tctaaaacag cttcattaaa atcccatagg ccttttctaa
     9421 agcaaaacgt atcgtcaaat tgcacaatgc gaacattgct atttaattga tatttcattg
     9481 agactcctta tttccaataa tcgtcatgtg aatcacatgc tgggtcaagc catccaagcc
     9541 tagcttttct tggaggtatt ccttattgta ccctccaata tcaacacttc catataccaa
     9601 agctgttgag accaattgaa cattttgagc aatctctcca gcttcaataa aggcataagc
     9661 agtagcttga tttccatatt tacgtgtgtt tttgatgtac tgataaacat agataagaat
     9721 gacattgcag ttttcggcag tgatcggtcc gtattcggca aaggctctaa tatcctcctg
     9781 atcactaaga tgatgacacc tcagcgcgtg ctgataagga aggtattcat aaaaaccgtc
     9841 cttgagtgtt tctacgtttc ttgcatagaa aaataaggtg atggggtaca gacccccacc
     9901 agaagcacaa tttcttaagg ctactgtctt agtcatgcct tctttgatga ttgcctgaga
     9961 gctgacacca caagcataat aaagcaaatc agccaaatcc tgcaaaggca tctcctcatc
    10021 tataaactgc ctatgacttc tccggttggt gatacaggtt gatagggctg ctgagacctt
    10081 cttagcttta ggaagtgcta tcgtgtttgc cctatcctca aaatagtcac tatttgaaaa
    10141 ggtggtcact gcagaatccg taaaaaactc agccacactg gtcttaaacc ctaggtaatt
    10201 gttattagcc ttgtaattca tcaaaaaccg ttggctaaga ttgtctgttt catcaggcat
    10261 caaatgctgt gccacaagct gttttgatgt ttttaatacc gtttgatgat gataggttga
    10321 taacgataag tgattggtat taaattcaaa taactgtcgt gcttcttctc ttgttaggtc
    10381 actttggtta tccgaacgtt gtttttcctt agaaaaaaat ggcataactg tcttcctgta
    10441 atatattaat aaataatagt aattagcagg taccgactag tacctgctaa ttactacaag
    10501 acgttgacat caagctgatt gtcttcgtct cttgtcatgt aacaccccta tccaacacca
    10561 gctaacacca tcaattacaa actgtaacct tagtcgctag caaactaatg attgtgacct
    10621 agctattaac tattaaatag aagtattaaa gtttacgctt ttggctcagc tgcaccataa
    10681 ttgttgttta tggtagtatt gccccatgaa gctgagacgc agcaacaaca agaacagcaa
    10741 cagcagcaac caccaggagc aacttgagtt gtttctgcta cactagtagc taaaatattt
    10801 gaagcaaatt gtaacataat gcttacctcc ttatatcgcc tgatcggtaa aacaaaacac
    10861 tgataagagt taaatgagaa tacctctcaa ctgatagcaa aagcaatcat gagcaggtat
    10921 ccagcaacac aaggctagct attttgtatc gcccttgtta aagtgaccat tcaattctta
    10981 cc
//
LOCUS       DARYXS010000068        10870 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.069, whole genome shotgun sequence.
ACCESSION   DARYXS010000068 DARYXS010000000
VERSION     DARYXS010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10870
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.069"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            6..596
                     /locus_tag="TV193_001443"
     CDS             6..596
                     /locus_tag="TV193_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1513626.1"
                     /translation="MEGITKSYGAKLILKDFSYTFEQGKKYLIKGASGRGKSTLLHII
                     KGTAVDSGKIAFITKDNHSFESYQANIGMVSQAPFLFNGTLEENICLNQEFSKENILA
                     VLDQVHLLEELPAGLGFQIENNGTNISGGQRVRIELARFLLRQKDILLLDEVTAALDK
                     DNARRVRELIFSLPITIIEVAHHVDQAIAYDDMIEL"
     gene            606..2168
                     /locus_tag="TV193_001444"
     CDS             606..2168
                     /locus_tag="TV193_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513627.1"
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTFLNNHQ
                     DTLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNYREMSHDKK
                     ISMLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQ
                     HVIGQKAEQKGSELAVARQKLLGLLSDVVAGHSTLIQNQALFASLKQVKKQSEHYESS
                     RQAFEIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQP
                     LKNIVDDMFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRT
                     LFSDLSFHFEKGKKYLIKGSSGSGKSTLFKLILQEMSPDEGTLDMVLTGGQTTDNYHH
                     RIGLIAQSPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNHQIVNNGEN
                     ISGGQKTRLEIARSLIRQKDVLLADEVTAPLDVKNAKTIRQLLFSLPVTVIEIAHQID
                     DTFIYDGDIDLS"
     gene            2551..3652
                     /gene="prfB"
                     /locus_tag="TV193_001445"
     CDS             join(2551..2622,2624..3652)
                     /gene="prfB"
                     /locus_tag="TV193_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEL1513628.1"
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPD
                     FWNDNMAAQKTSQELNELKLTYQTFHDMQELSDETELYLEMLDEDDSVKEELEASLIK
                     LSQMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKV
                     ETLDYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVE
                     VMPELDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFEVAQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            3703..4395
                     /gene="ftsE"
                     /locus_tag="TV193_001446"
     CDS             3703..4395
                     /gene="ftsE"
                     /locus_tag="TV193_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEL1513629.1"
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKS
                     TFIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENV
                     AYAMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIV
                     RDEEKGDYGYDD"
     gene            4388..5317
                     /locus_tag="TV193_001447"
     CDS             4388..5317
                     /locus_tag="TV193_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513630.1"
                     /translation="MIRHFFRHIWESIKNLRRNLLMTFASVSMVTVTLTLLGVFAATL
                     LNIQRVASGVENNIQINAYLQVDSTDAAKMVQSINGEQINNENYHKIYDQIAGLKGVE
                     RIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQG
                     IEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTIMSRQRDIAIM
                     RLVGAKNSYIRGPFFFEGAWVGLFGAILPSLIIYYGYEFAYKHFTPELQHNSLSMYPI
                     NPYVYYLIGMLFVIGIIIGSLGSVLSMRRYLKF"
     gene            complement(5707..6348)
                     /locus_tag="TV193_001448"
     CDS             complement(5707..6348)
                     /locus_tag="TV193_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1513631.1"
                     /translation="MTIMTLMNPVAGENTYLLVNDEAILVIDPGSKGQAILSQIHAIN
                     KPVAAILLTHTHYDHIMSLELVRESCQHPPVYVAKEEADWLYKPEMNLSGLIRHADLP
                     DIICKPAEKLFQYQTPYQLAGFHFSVVPTPGHSAGGVSFIFEQEEAVFTGDALFRESI
                     GRTDLPTGNLEQLLASIRDKLLTLPNHYQIYPGHGSATTISHEKNSNPFLRQR"
     gene            6685..9156
                     /locus_tag="TV193_001449"
     CDS             6685..9156
                     /locus_tag="TV193_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEL1513632.1"
                     /translation="MINEFSQKYAVIDLEATSPGPTASIIQVGIVIVEGKEIVDSYQT
                     DINPHEPLSDHIKALTGITDQQLAQAPDFSQVARTIFELIEDCVFVAHNVTFDANLLA
                     EALFLEGYDLLTPRVDTVELAQIFYPSLEKYSLSHLSEVLDLNLSDAHTAIADAQATA
                     NLFIKLLHKIESLPRECLETLLLYADSLLYETAMIVRQALAVSRPYSTSDYIKINQIL
                     LKKPDQLTKPYQLSQSFEINAALLGLEERPKQLSFAKIVEETLFQTEPAFIEAQAGIG
                     KTYGYLLPLLAQKHQTQILVSVPTKLLQDQIMANEVRAIQEQFHIDCHSIKGPANYIK
                     LDSFQESLNQLDDNRLVNRYKMQLLVWLLETRTGDLDEIKQKQRFAAYFDQIKHDGSI
                     QQTSPFYAYDFWQQSYQRAKSARLLITNHAYFLHRIQDDKAFAKGKILVFDEAQALML
                     QLEELAHQRLNIADTLQELQEQLAVPSSLLEQRLLEGIAFELNQLSSHYHQEEEKQQA
                     QASQHLLRLQEHVKELGAAASQSLKQLFKQQEMDYWVSSEQQADKRQTFLNGSSRTVL
                     QFKALLPEIFKAYFVSATLQISPSISLADLLGFDTYSYHQLAKEKSTQQLVVIDQDMP
                     LIKDLTDEAYTQTIAARLLVLHQQQQVPILVLFNAKKHMLMVSDYLEANQVQHLTQGK
                     NGTAYHIKKRFDRGEQSMLLGLAAFWEGVDFVHADRMIEVITRLPFDNPEDIATQKMQ
                     RYLQAAGKQPFNDYFLPMTILRLKQAIGRTLRRKEQKSAVLILDRRILTMSYGQTILH
                     SLEEEFLISQQNFQDSLAEIGDFLI"
     gene            complement(9330..10496)
                     /locus_tag="TV193_001450"
     CDS             complement(9330..10496)
                     /locus_tag="TV193_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1513633.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWNMYVDNRLKTGSWKPDTEANKEAIYK
                     THFKKYLGKTKMKDISRIEYENHINGMRKNYSKNTLRLIHSVLNAMLNHAVTNKMLDD
                     NPIDGITIGDSEIIPVNKRISLEEFKEWDSWAKKSLIQYDYTIVRMTYFGARSSEVVA
                     IKIGNLTKLENGRYRILLDESRTYHRPNGGGMKTPGSERFMEVDLETSHYIDDVVVES
                     KRIAKKYNRILSKEDYLFLTNFKNAKKELLGMPISIRRVYKLFNTVNEKSGMHVTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSTSYMTSKYTHIKEEVAGSVTDRFMSALN"
BASE COUNT         3073 a         2109 c         2379 g         3309 t
ORIGIN      
        1 tggctttgga agggatcaca aagtcctatg gcgccaagct gatccttaag gatttttcct
       61 atacctttga acaggggaaa aaatatttga taaagggtgc cagtggtaga ggtaagtcga
      121 ctctgttaca cattattaag ggaactgctg ttgactcagg taaaatagcg tttatcacca
      181 aagacaatca ctcatttgaa agctatcaag ctaacattgg catggtgagt caggcacctt
      241 ttctctttaa tggcaccttg gaagagaata tctgtctgaa tcaggagttt tccaaggaga
      301 atatccttgc tgtcttggac caagttcacc tgttggagga attaccagct ggtctaggct
      361 ttcagataga aaataatggg accaacattt cgggcggcca gcgagtgcgc atagaattgg
      421 ctcgattttt gctacgtcag aaggatattt tattgcttga tgaggtcaca gcagccttgg
      481 acaaggacaa tgctcggcga gtaagggagc tgattttttc tcttcctatt accatcattg
      541 aggtggctca tcatgtggat caagctatag cttatgatga tatgatagaa ttgtaggtga
      601 ttaagatgtt taagtatttt aataaatatc tagtgacact aacgcttgtt gcatgtgcct
      661 taaacagtct tgtctttctg attgaaccct tgatcactag taagattttt gatttaacgt
      721 tcttaaataa tcatcaagac accttgtcct ttttaggcta tggtctgacc ttatacgtgg
      781 tcttatattc tgttatgttc attgctaatc ttctgatcaa ccatatcatg acgattgggt
      841 gtggtagaat caggttgcgt ctctatcaga atttaatctt aaattatcgg gagatgagtc
      901 atgacaagaa aatttctatg ctgactcaag atgtagaata ttatctatgg aatcacatca
      961 gccctagcat tcttctcgta tcacacgtga gtaatgtcct tttgctcagt gcttacctgt
     1021 tatcaaaaaa catgctaatt ggtcttattt ttattgcatg tgcttttgta tttttagtgg
     1081 ttcagcatgt gattggtcaa aaggcagagc aaaaaggtag tgagctggca gtagcgagac
     1141 aaaagctgct tggcttatta agtgatgtgg ttgcggggca ttcgacatta attcaaaatc
     1201 aagctctttt tgctagcctc aaacaggtaa aaaaacagtc agagcattat gagagctcac
     1261 gtcaagcatt tgagatattt aggtctttct ttaccctatt ggcacatctg atgctgttta
     1321 tttctcaatt cttgcccatt tttttaggct tagccttaac cttattaggt gttaagctga
     1381 gaacaactga tcttattgcc atgtttattg cagcaacgcg cttagaacag ccactcaaaa
     1441 atattgttga tgatatgttt aggcttaatg gtgcaaaagc cattgctaag cattttgaga
     1501 cacttttaga gcagcctatt ccaaaatacc agtcgcatgc tatgacaggt gatccttttg
     1561 aatgcttaga tggtcatcat ctggcgaaat catttgcagg taggacctta ttttccgatc
     1621 tctcttttca ttttgagaag ggaaagaaat acctgattaa gggatcaagt ggatctggta
     1681 aatccacact ctttaagctt atcttacagg agatgagtcc tgatgagggg acactagata
     1741 tggtattgac tggaggtcag acgactgata attatcacca tcgcataggg ctgattgcgc
     1801 agtcgcctta tctttttaac gatagcattc ggtataattt gaccttgggg gaggcgtttt
     1861 ctgatgagtt gcttttagaa aagctagaac aggttggctt gactgatgaa tttgacgata
     1921 ttttaaacca ccaaattgtt aataacggag aaaatatctc aggtggtcaa aagacacgtc
     1981 ttgaaatcgc aagaagcctc attagacaaa aagatgttct tctagcagat gaagtgacgg
     2041 ctccacttga tgtcaaaaat gctaaaacta tccgacagct actatttagt ttaccggtaa
     2101 cagttattga aattgctcat cagattgatg acacctttat ctatgacggt gatattgatt
     2161 tatcgtagaa aatatcatca cattgcttag aaataataat tgatgcttat gaaattgtca
     2221 ttcacacagt gaatggcttt ttcttaggct aaattttcca tgtggagctt gatctgatag
     2281 gctatctgag aaaaaaagct aacaacagcc atgttttttg gggctatgac tgttctaata
     2341 cgagctgcct ctagctgctg gtatataaga ggtgacatga ttgtcacaat tcgtcatcat
     2401 tttgtcgtta aatttttaca tagatttctt atgctagtca tggcagagct ccttacccta
     2461 aaaagaaggg aatttagctg atgggaaata gcaattctaa agcctttatg ataaaatgaa
     2521 aaaagacact ataatagaag aggtaactgt atggaagtgg cagaaatgcg ccagcaaata
     2581 gtagaaaaca aagagaagtt gactagcttc aggaggtctc tttgacttag agcgtttgga
     2641 ggaggatata gctctcttag aaaataagat gacagagcct gatttttgga atgataatat
     2701 ggcagctcaa aaaacctctc aggaattaaa cgagctcaag ctcacctatc aaacctttca
     2761 tgatatgcag gagctatctg atgagacaga gctttattta gaaatgcttg acgaggacga
     2821 tagcgtcaag gaagagctag aagcaagcct gattaagctc agccagatgc tagcaagcta
     2881 tgaaatgacg ctgcttttgt ctgagcccta tgatcatagc aatgcaatcc tagaaattca
     2941 cccaggttca ggtggcactg aagcacaaga ctgggcagac atgctttttc gcatgtacac
     3001 tcgctttgga aatgccaagg gctttaaggt agaaactctg gactatcaag caggagacga
     3061 ggcaggaatt aagtctgtga ccctttctat tgaagggcca aatgcttatg gcttcttaaa
     3121 atcagaaatg ggagtacatc gtctggtgcg tatttctcct tttgactctg ctaagcgtcg
     3181 tcacacctcc tttgtttcag ttgaagtcat gccagagctt gatgatacca tcgaggtgga
     3241 gatacgtgat gatgacatta agatggacac cttccgctca ggtggtgctg gtgggcaaaa
     3301 tgtcaacaag gtctcaactg gggtacgctt gacccatatc ccaacaggaa tcgtagtggc
     3361 gtcaacagtt gaccgcaccc aatatggcaa ccgtgatcgc gctatgaaaa tgcttcaagc
     3421 caagctttat cagttagagc aggagaaaaa ggcagaagag gtcaatgccc tcaaggggga
     3481 taaaaaggag atcacctggg gcagtcagat caggtcctat gtctttacgc cttatacgat
     3541 ggtgaaggat catcgtacca attttgaggt ggctcaggtt gataaggtga tggacggaga
     3601 tattgagggt tttattgacg cttatctcaa atggcgcatg ggtgaggatt aaagtgatcc
     3661 ccactcagat aaacactaac agcttagaga aggaagaata agatggcatt aattgaaatg
     3721 aagggtgttt ctaagaaata ccgtcgctcg acaacagctc tgagagacat taatgtctca
     3781 gtcaatcaag gggaatttgt ctatattgtt ggtccatcag gagctggtaa atcaaccttt
     3841 atcaagcttc tttatcgcga agaaaagcta agctcaggca gcctaaaggt gggtgagttt
     3901 gacttaacca agctaagagg acgtgaggtt ccaattttac gtcgcagcat tggtgttgtt
     3961 tttcaggatt ataagttgct ccctaaaaaa acggtctttg aaaatgttgc ctatgctatg
     4021 gaggttatcg gagagagacg tcgccatatc aaaaagcgtg ttcctgaggt tctagacctt
     4081 gtcgggttaa agcataagat gcgctccttt cccaatcaat tgtcaggtgg tgagcagcag
     4141 cgtgttgcga ttgcacgcgc tattgtgaac aatcccaagc tcctcattgc agatgagcct
     4201 acaggcaatt tggatccgga aatttcttgg gaaatcatgc acctgcttga gcgtatcaat
     4261 ctacagggga caacgatatt aatggcaacg cataacagtc atatcgttaa tactcttcgc
     4321 catcgcgtgg ttgcgattga aaatgggcgt attgtccgcg atgaggagaa aggagactat
     4381 ggttacgatg attagacatt ttttccgtca tatctgggaa tctatcaaaa atttaaggcg
     4441 taatctcctc atgacctttg cgtcagtcag tatggtgacc gtcaccttaa ccctgcttgg
     4501 ggtctttgct gcaaccctgc tgaacattca acgtgtcgct tctggcgtgg aaaacaacat
     4561 tcaaatcaat gcttacttac aggttgattc gacagatgct gctaagatgg ttcagtcgat
     4621 taatggagag cagataaata acgagaatta ccataagatt tatgatcaga ttgcagggct
     4681 aaagggtgtt gagaggatta ttttctcaag caaggacgag cagctgcaaa agctacagga
     4741 tagtctgggc gatgtctggg gcatgtataa tgaggatagt aatcctctgc aagacatcta
     4801 tatcgtagag accaagaccc ctaagcaggt caaatcagtt accaaggcca tcaaaaagat
     4861 tcaagggatt gaagatgcgg actatggtgg tattaattct gataagcttt ttaagttttc
     4921 aaaactgatt caaacatggg ggattatcgg aacgctgttg ctcctgttta ttgcgatctt
     4981 tctgatttca aataccattc gcatgaccat catgtctcgt cagcgcgata ttgcgatcat
     5041 gcgtctggtt ggtgcgaaaa attcttatat tcgtggccca ttcttttttg aaggggcttg
     5101 ggttggtctg tttggtgcga tattgccatc gttgattatt tattatggct acgagtttgc
     5161 ctacaagcat ttcaccccgg aattacagca taatagcctg tctatgtacc ctatcaatcc
     5221 atatgtttat tatttaattg gcatgctttt tgtgattggt attatcattg ggtcactagg
     5281 atcagtctta tctatgagac gttaccttaa gttttaattg aaagagcttc tagcctgtgt
     5341 gcctggactg gtaccctgcg gttagggctc tttttgcttt tggggcaatg cttgctagat
     5401 aagcaaacaa tagcttaagc ccataccatt aagtattggg cttaagctat tgttatagtt
     5461 gtttaggtaa tagaagcagc cggaacttga ggtgtcctat ctaggtcttg agctatagct
     5521 tttctggcta gttggtgttt cttcacgtaa cagcgatttg tcgaacgata aggtgctctt
     5581 cttgtgatag ctggcttgta gtgatcgaca ggtgctaagt caaattagcc atcctgatgg
     5641 actggagtca tagcttttgc tgctgcgcct ggttgggcat agactgggca tctcggtagc
     5701 ttgagcttat cgctgcctca gaaagggatt gctatttttt tcatggctaa tggtggtagc
     5761 tgagccatgc cccggataaa tctgataatg gttaggaagt gttagcagct tatcacgaat
     5821 gctagcaagc agctgttcaa gatttccagt cggcaaatct gttctaccga tgctttctct
     5881 aaacagagca tcgccagtaa acaccgcctc ctcctgctca aagataaagg aaacgccacc
     5941 ggcagagtgt cctggtgttg gcactactga aaagtgaaat ccagctagct gataaggtgt
     6001 ctgatactga aagagctttt ctgctggttt gcagatgata tcaggcagat cagcgtgacg
     6061 tatcagtcct gacaggttca tttctggttt ataaagccag tccgcctcct ccttggcaac
     6121 atagacagga gggtgctggc agctctctct caccagctct aggctcataa tgtgatcata
     6181 atgcgtatgg gtcagtagga tagcagcaac aggcttgttg atggcatgga tttgtgataa
     6241 aatagcctgc cccttgcttc ctgggtcaat gactaaaata gcctcgtcat tgacaagaag
     6301 gtaagtgttt tcacccgcaa cgggattcat cagtgtcata atagtcatac ccttagttta
     6361 ccaaaatctg actcaaaaga cagctcaaaa ccacctcttt tgataaaagt gatctgttta
     6421 atggttttga tggctaagcc aagatagctc cagcttaaag gctgcttttt ttaattaata
     6481 ggagcaaaaa ggagctgcct cagcgctaac agctaatcag agtattagct ctctagtgtc
     6541 atagcaagga agtaggctgg ggcgattaaa aggcttgata actagctttt tatgatactg
     6601 actagcccta ttgagctgag ctaagactgg tattgtcaga tttaggcaaa gcctgtcaga
     6661 aaacgtgcta taatagatag tactatgatc aatgagtttt cacaaaaata tgctgtgatt
     6721 gacctggaag ccactagccc aggtccaaca gcgtctatta ttcaggttgg cattgtgatc
     6781 gttgaaggaa aagaaatcgt tgattcgtat caaactgata ttaatcctca tgagcccttg
     6841 tcagaccata tcaaagcact cacaggtatt acagaccagc agctagctca ggcaccggat
     6901 ttttcacagg tagcaaggac catttttgag ctgattgagg actgtgtttt tgttgctcat
     6961 aatgtcacct ttgacgccaa tttgttggca gaagccttat ttttggaggg ctatgatctc
     7021 ctcactccta gagtggatac tgttgagctg gctcagattt tttaccccag cctagaaaaa
     7081 tacagcctta gccacctatc agaggtgcta gacctaaacc tatctgatgc tcataccgct
     7141 attgctgatg ctcaggcgac tgctaactta tttatcaagc tgcttcacaa gatagagagc
     7201 ttgccaagag aatgcttgga gactcttttg ctgtatgctg atagtctgtt atatgagaca
     7261 gctatgattg tgagacaagc ccttgcagtc agtcggcctt attctacgag tgactacatc
     7321 aagattaatc agatcttgct aaaaaagccg gatcagctaa caaagcccta tcaattatcc
     7381 cagtcctttg agattaatgc agccctctta ggtcttgagg agcgccccaa gcagctcagc
     7441 tttgcaaaga ttgttgagga gactcttttt cagaccgagc cagcctttat cgaggctcag
     7501 gcaggcattg gtaaaaccta tggctattta ctgcctctcc ttgcacagaa acatcagacc
     7561 caaatcttgg ttagtgtgcc aaccaagctg ctacaggacc aaatcatggc taatgaggtg
     7621 agggctattc aggagcagtt tcacatcgat tgccatagta tcaaggggcc tgctaattac
     7681 atcaagctag acagctttca agagagcctc aatcagcttg atgacaaccg cttggttaat
     7741 cgctataaaa tgcaattgct ggtttggctt ttggaaacaa ggactggtga tttagatgaa
     7801 atcaagcaaa agcaacggtt tgcagcttac tttgaccaga tcaagcatga tggcagtatc
     7861 cagcagacct cgccctttta cgcttatgat ttttggcaac aaagctatca aagggctaag
     7921 tcagctcgct tgctgatcac caatcatgcc tattttttac accggattca ggacgataag
     7981 gcatttgcca agggtaagat tctagtcttt gatgaagctc aggccttaat gctgcagcta
     8041 gaggagctag ctcatcagcg actaaatata gctgatacgc tccaagagct tcaagagcag
     8101 ctagctgtgc caagcagctt gcttgagcaa cgcttgctag agggcattgc ctttgagctc
     8161 aatcagttaa gcagtcatta tcatcaggag gaggagaagc agcaagctca agcctcacag
     8221 catttgctgc ggctccaaga gcatgtcaag gagctaggtg ctgcagcctc tcagagcctc
     8281 aagcagctgt tcaagcagca ggaaatggat tattgggtga gcagtgagca gcaggctgac
     8341 aagcgccaaa cctttttaaa tggcagcagc aggacggtcc ttcagtttaa agcattgcta
     8401 ccggagattt ttaaggccta ctttgtctca gctactctac agattagccc tagcattagc
     8461 ttggctgatt tattgggctt tgacacttat tcttatcatc agctggctaa ggagaaaagc
     8521 actcagcaat tggttgtcat tgaccaagac atgcccttga ttaaggactt gactgacgag
     8581 gcttacacac agaccatagc agcaaggcta ttagtgcttc atcagcaaca gcaggtacct
     8641 atcttagtgc tctttaatgc taaaaagcac atgctcatgg tttctgacta tttagaggct
     8701 aatcaggtgc agcacttgac acaaggcaaa aacggtacag cctatcacat caaaaagcgc
     8761 tttgatcgtg gtgagcaatc aatgctgctg gggcttgcag ccttttggga gggagttgac
     8821 tttgttcatg ctgatcgcat gatagaggtc attacccgcc tgccctttga taatccagaa
     8881 gatattgcca ctcaaaaaat gcagcgctac ctacaggcag caggtaagca gccctttaat
     8941 gattattttc tgccgatgac gatcttaaga ttaaagcagg cgattggtcg aaccctgcgt
     9001 cgaaaagagc agaaatcagc agttttgatc ttagatcgtc gcattctgac catgtcctat
     9061 ggtcagacca ttttgcacag cctagaagag gaatttctga tatcacaaca aaatttccaa
     9121 gatagtctag cagaaatagg cgattttttg atataatgaa aaatagtaat ttttatttag
     9181 ttattttaat ttatttattt tgcaaatgtt tatttatagg catttgcttt tttgtttaat
     9241 tgataccaaa taataaaaat ctataaattg tcggggaata tatcggggga tttgttaatt
     9301 taagcatttg tataaatttc cccgactaac tagtttaaag cgctcataaa tctatcagta
     9361 acactaccag caacctcctc ctttatgtga gtatatttgc tagtcatgta acttgtagaa
     9421 tgacctagtg ctgcggccat atgttcaatt gggacacctg ctatctgccc ttgggtggcg
     9481 aaaaagtggc gcatcatgtg tggggtaaca tgcataccag atttttcatt gacagtatta
     9541 aaaagtttat agactcgcct aatagagatc ggcattccta aaagttcttt tttcgcattc
     9601 ttaaagttag tcaaaaatag gtaatcctct tttgataata tacgattata cttctttgca
     9661 atccttttag actcaacaac aacatcatca atataatgcg atgtttcaag atcaacttcc
     9721 ataaaccgct ctgatcctgg cgttttcatt cctccaccgt ttggacgatg gtacgtccta
     9781 gactcatcta gcaatattcg atatctacca ttttcaagct ttgttaaatt gccaattttt
     9841 atggcaacaa cttcgctact acgagctccg aagtaagtca tacggacaat agtataatcg
     9901 tattgaatca atgacttctt ggcccatgaa tcccactctt tgaattcttc aagcgatatt
     9961 cttttgttaa cgggtataat ctcactatcg ccaatagtta tcccatcaat tggattgtca
    10021 tctagcattt tattggtgac tgcatgatta agcattgcgt tgagtactga atggatcaag
    10081 cgtaaagtgt tctttgaata attcttacgc ataccattaa tatgattttc atactcaatt
    10141 ctagaaatat ctttcatttt agtcttgcct aaatattttt tgaagtgagt tttgtatata
    10201 gcttctttat ttgcttcggt atcaggtttc catgatccgg tctttaggcg attatctaca
    10261 tacatattcc agtactgatc aactgtcaaa tttttgttat aagcaaaatc attgttttct
    10321 attttttgct caatttcagt aagtgcagct ctggcttcct gtagcgtttt taagttgctt
    10381 tttgtagcct ctttcttttt accttttaag taataacccc tacggacgta gtagcgttta
    10441 cctttctttg tatcgtaggt aaagatattt gggtattttg ttttgttgta tttcatttta
    10501 aaatcctttc atgtattttg acttttggac gaggtcgttt gaaaggatat tggcatcacc
    10561 tcctttgtgt gatataatta ggtataataa aacgcccttt ttaatggttg ttttatattt
    10621 tgtgtagtct ccacgttgcg ctttggtcgg ttgtaacgtg gggctttttt gttttattta
    10681 ctaaatttta aatatgctgg tattgataaa actaatgtaa aaaacaaccc aactaagaac
    10741 tctaagaatt tacccttaag caaaaaactt atagctacta agcagaataa gataccaatt
    10801 aaaaacatta ttgctgcaat tgcatctgta aatgtaatat ttttagattt gctttttgat
    10861 gtattcgaca
//
LOCUS       DARYXS010000069        10868 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.070, whole genome shotgun sequence.
ACCESSION   DARYXS010000069 DARYXS010000000
VERSION     DARYXS010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10868
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.070"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            347..829
                     /gene="rimP"
                     /locus_tag="TV193_001451"
     CDS             347..829
                     /gene="rimP"
                     /locus_tag="TV193_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEL1513634.1"
                     /translation="MNIANTAIIDIVTQIVEPVIKAPYELVDIEYDKMGNDYVLSILV
                     DKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVG
                     SYINVSLYRAIDKVKVFQGDLVAFDGDTLTIDYLDKTRHKTVEIPYQAVAKARLAVKL
                     "
     gene            939..2093
                     /gene="nusA"
                     /locus_tag="TV193_001452"
     CDS             939..2093
                     /gene="nusA"
                     /locus_tag="TV193_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEL1513635.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIEAVTESLKSAYKRRYGQAES
                     CVIEFNDKTADFQVFTVREVVEEVFDSRLEISLNDALAISSAYELGDKIRFEESVSEF
                     GRVAAQSAKQTIMERMRRQMREITFNEYKQHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRYDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDDDLKRATVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYERLEAEKEAAMTEAVATEELLTNEEV"
     gene            2109..2405
                     /locus_tag="TV193_001453"
     CDS             2109..2405
                     /locus_tag="TV193_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEL1513636.1"
                     /translation="MPKVKKIPLRKSLVSGEIIDKRDLLRIVKNKEGQIFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMEVPESFYDEVIAHVDHKVKRRELGLE"
     gene            2398..2700
                     /locus_tag="TV193_001454"
     CDS             2398..2700
                     /locus_tag="TV193_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEL1513637.1"
                     /translation="MNSLNRLSHLIGLAQRAKKVISGEELVIKAIRHQEVNLVFLAND
                     AGPNITKKVTDKSNYYNVEVSTVFSALELSAALGKPRKVVAIADAGFSKKMRTLMK"
     gene            2720..5590
                     /gene="infB"
                     /locus_tag="TV193_001455"
     CDS             2720..5590
                     /gene="infB"
                     /locus_tag="TV193_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEL1513638.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVERAKSLGLDVKSHASSVEEADAN
                     KIASSFSAGVTKNVQAGSAKDKQVAEQKAKAAKATTPQPAASKAAEKPAAATQEASQP
                     VAVKPKSRNFKAEREARAKEQVARRQAGQNRSNDRKSDYRQLGRSQGQQTERAGHKSQ
                     NQQRDRRFDNRPSSGNNRNDGHRQAGNRDKNRSFNANSRQQDTGRQGQTQAGAPKIDF
                     KARAAALKAEQNAEYARQRESRFREQEEAKRLEQQARQEAKAAALKAQTEDKKHREAS
                     AKATESVASMAAASVAKPVDKRRKKQNRPDKGHDRDHGLEDGQKKNKKSWNSQNQVRN
                     QKNSNWNNNKKNKKGKHHKNSNTAPKPVTERKFHELPKEFEYSEGMTVAEIAKRIKRE
                     PAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDEADIERFFTDDSYL
                     NPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKI
                     TFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAIN
                     KIDKPGANPERVISELAEHGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEE
                     LKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLHVQDPIVVGNTFGRVRAMTNDLG
                     RRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRV
                     SLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAINE
                     SDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDP
                     EYQEKMLGEAIIRETFKVSKVGTIGGFMVVNGKVTRDSSVRVIRDSVVIFDGKLASLK
                     HYKDDVKEIGNAQEGGLMIEGFNDIKVDDTIEAYVMEEITRK"
     gene            5780..6130
                     /gene="rbfA"
                     /locus_tag="TV193_001456"
     CDS             5780..6130
                     /gene="rbfA"
                     /locus_tag="TV193_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEL1513639.1"
                     /translation="MTNHRIDRVGMEIKREVNEILHKKVRDPRVQGVTITEVQMLGDL
                     SVAKVYYTIMSDLASDNQKAEIGLKKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELEKKQ"
     gene            complement(6202..7239)
                     /locus_tag="TV193_001457"
     CDS             complement(6202..7239)
                     /locus_tag="TV193_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1513640.1"
                     /translation="MIKEKTLTYLKRQLILLALLLTAIGSQTIVQASTRSWKSWFIEQ
                     YFWLKRDKSYYAEQDENTFYNYVKSAGEKSNQGFNLTQNEVNGTLKTEYRDNMQVHSW
                     NENSTNPSNQKVILYLHGGSYLNNPTSYHIDMLKTLSTSLDAKIVLPIYPKAPTYTYD
                     VAMPRLVSLYQDILKSTNNNANNITIMGDSAGGGLALGLALALKNEDIKQPKDIILLS
                     PWLDVTLSNPEIPNYEASDPILSARGLRIVGDIWARRGENNTKHPYVSPIYGDTSNLA
                     PITMFVGTHEIFYPDITKFDGMLKQKGHKHQLFVGEKMNHVYPIYPIEEAKTAQYQII
                     DTIKKEYEPQK"
     gene            7469..7903
                     /locus_tag="TV193_001458"
     CDS             7469..7903
                     /locus_tag="TV193_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEL1513641.1"
                     /translation="MDTISDAEWEVMRVVWANGSMKSSEIIAILHEKHHWSDSTVKTL
                     IGRLVKKKALRADRQGRSYIYQSLLDQDRRQLAMLRERLDGMCQRHHSRLLLALLKDT
                     PMTLEDIQAFQLLLEAKKVGAVSHVRCDCVPGQCHCQKKERI"
     gene            7903..10133
                     /locus_tag="TV193_001459"
                     /pseudo
     CDS             7903..10133
                     /locus_tag="TV193_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678421.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
BASE COUNT         3176 a         2027 c         2694 g         2971 t
ORIGIN      
        1 ctgatgggag gttttttcgt tttggtaaag accatgaagc agccgcaaat aatattttag
       61 ttgtcttttt taccctttaa tattttattt tatcatatga atacagaggt tagaggggat
      121 aaggaaagag aaaaaagcaa ggttaaagat ctcctctcct tttaaaaaat aggatttttg
      181 aggtcttatt gacactttta gtagggattt tcttgcaatt cattttgatt gtggtataat
      241 aggttaaagc aatacagaag ggtggtgaga aatatctcgc cacttttgtg ttgattatca
      301 agaggacaag gctatagagg tatagcagtc atcagtaaag gaggttatta acatcgcaaa
      361 cacagctatt attgatattg ttacccaaat cgtagaacct gtaattaaag caccctatga
      421 attggtcgac atcgaatacg acaaaatggg caatgattat gtccttagta tcttagttga
      481 taaggcttct gggattaccg ttgaggatac tgctgagctt acagagttaa tcagtccact
      541 cttagatacg atttctccag accctttccc agatcagtat atgctggagg tttccagtcc
      601 tgggctagag cgtccattaa agactgctga gagcttgaag gctgctgtag gctcatatat
      661 taatgtcagc ctctatcggg caattgataa ggtgaaggtt tttcaaggag atttagtggc
      721 ttttgatggt gataccctaa ccattgatta tctagataag acgcgtcaca aaacagttga
      781 gattccttac caagcagtgg ctaaggctcg tttagctgtc aaattataag gcaattgctg
      841 agcgatttgc tttagtcggt tggctaagcc ctaaatggat taatttataa gataagaaag
      901 gatttttacc aagctttgag agcaaggtag acaacattat gagcaaagaa atgctagaag
      961 ccttccgtat tttggaagaa gaaaaacaca ttgataaggc agatatcatt gaggcagtca
     1021 ctgaatcact gaaatcagct tataaacgtc gttatggtca agcagaatcc tgcgtcattg
     1081 aatttaatga taaaacagca gattttcagg tttttacggt tcgtgaggtt gttgaagagg
     1141 tatttgatag ccgtctggaa attagcctga acgatgccct tgccattagc tcagcctatg
     1201 agttaggaga taagattcgt tttgaagaat cagtcagcga gtttggacgt gtggctgctc
     1261 agtctgcaaa gcaaaccatt atggaaagga tgcgtcgtca gatgcgagaa atcaccttca
     1321 atgagtacaa gcagcatgaa ggtgaaatca tgacgggtac ggttgagcgt tttgaccaac
     1381 gtttcattta tgttaacctt ggttccttag aggctcagct ctcacatcag gatcaaatcc
     1441 caggagaaac cttcaaatca catgatcgga ttgatgtcta tgtctacaag gtggaaaaca
     1501 atccaaaggg ggttaacgtc tttgttagtc gtagtcaccc tgagttcatc aagcgcatta
     1561 tggaacagga aattccagag gtttttgatg ggaccgttga gattatgagt gtttctcgtg
     1621 aggctggtga ccgtactaag gttgctgtgc gtagccacaa tcccaatgtt gatgcgattg
     1681 gaacgattgt tggtcgtggc ggcagcaaca tcaaaaaggt tatcagtaaa ttccatccaa
     1741 agcgctatga tgctaagaca ggacttgaga tcccagtaga agaaaatatt gacgttatcc
     1801 aatgggtaga tgaccctgct gaatttatct acaatgccat tgcacctgct gaggttgata
     1861 tggttctctt tgatgatgac gatcttaagc gtgcgactgt ggtggtgcct gataataagc
     1921 tatcgcttgc tattggtcgt cgtggtcaaa acgttcgttt ggcagctcat ttgacaggct
     1981 atcgcattga catcaaatca gccagtgaat atgaacgcct tgaagcagaa aaagaagcag
     2041 caatgactga agcagtagct acagaggagc tcttaaccaa cgaggaagtg taagaaaaga
     2101 ggtgttttat gcctaaagta aaaaaaatac ctttacgtaa gtcgcttgtt tctggtgaga
     2161 tcattgataa gcgtgacctc cttcgtattg tcaaaaataa ggaggggcag atttttattg
     2221 atccaaccgg caagcaaaat gggcgtggtg cttatatcaa gctagataac caagaagcac
     2281 ttatggcaaa gaaaaaacag gtgtttaatc gtagcttctc aatggaggtg ccagagagct
     2341 tttacgatga agtgattgca catgttgatc acaaagttaa aagaagagag ctaggccttg
     2401 aatagtttaa atagattatc tcatttgatc ggactggctc agcgggccaa aaaagtgatt
     2461 tcaggtgagg aattggtcat taaagccatt cgacatcagg aagtcaatct tgttttttta
     2521 gccaatgatg ctggcccaaa tatcactaaa aaagtaacag ataaaagtaa ttattacaat
     2581 gtagaagtct ccacagtgtt tagtgcactg gaattaagtg ctgcacttgg caagcctcgt
     2641 aaggtggttg ccattgcaga cgctggattt tcaaagaaaa tgaggactct tatgaaatag
     2701 acgaatagga ggacacaaat tgtcaaagaa aagattacat gaaattgcca aggaaattgg
     2761 caaaagtagt aaagaagtcg ttgagcgtgc taaatcctta ggattagatg tcaaaagcca
     2821 tgcgtcaagc gtcgaagaag cagatgctaa caaaattgcc tctagctttt cagcaggtgt
     2881 gactaagaat gttcaagcag gttcagcaaa agacaagcaa gtagcagaac aaaaagcaaa
     2941 agcagctaag gccactacac cacagccagc agcctctaaa gcagcagaaa agccagctgc
     3001 tgcgacacaa gaagcatcac agccggttgc tgttaagcca aagagccgca atttcaaggc
     3061 agagcgtgaa gcacgtgcca aggagcaggt agcgagacgg caggctgggc aaaatcgctc
     3121 taatgaccgc aagtcagact atcgtcaact tggacgatca caaggtcagc agacggagcg
     3181 agctggccac aagtcacaaa atcagcaaag agatagacgc tttgataaca ggccatcatc
     3241 tggaaataac cgaaacgatg ggcatagaca agctggtaat cgtgacaaaa accgttcctt
     3301 taacgctaat agtcgtcaac aggatacagg acgtcaaggg cagacccaag ccggtgctcc
     3361 taagattgat tttaaggcgc gtgctgctgc cttaaaggct gagcaaaacg cagagtatgc
     3421 cagacaaagg gaatcacgct ttcgtgagca agaggaggct aaacgcttag agcaacaggc
     3481 aaggcaagag gctaaggcag ccgccctcaa ggctcagaca gaggacaaaa agcatcgtga
     3541 agcctcagct aaggctactg agtcggttgc tagtatggct gctgcatcgg tagcaaaacc
     3601 ggttgataag cgtcgtaaaa aacaaaatcg tccagacaaa gggcatgatc gggatcatgg
     3661 cctagaagat ggacaaaaga aaaataagaa gagttggaat agtcaaaacc aagtgagaaa
     3721 tcaaaagaat agtaactgga ataacaacaa gaaaaacaaa aaaggtaagc atcataagaa
     3781 tagcaacaca gctccaaaac cagtaacaga gcgtaaattc catgaattac caaaagaatt
     3841 tgaatattca gaaggaatga ccgttgctga aattgcaaaa cggatcaagc gtgagccggc
     3901 tgagattgtc aagaaattat ttatgatggg tgtgatggca acgcaaaacc aatccttaga
     3961 tggtgatacc attgagctct taatggtgga ttatggcatt gaagctaagg ccaaggtgga
     4021 ggttgatgaa gctgatatcg agcgcttctt tactgatgat agctacctta atcctgagaa
     4081 tattgttgag cgtgcaccgg ttgttaccat tatgggacac gtcgatcatg gtaagacgac
     4141 cctgcttgat acccttagaa attctcgtgt tgcaacagga gaagcaggag ggatcaccca
     4201 gcatattgga gcttaccaga ttgaggaggc aggcaagaag attaccttct tggatacacc
     4261 aggacatgct gccttcacaa gcatgcgtgc acgtggagcg tcagtgacag atattaccat
     4321 tttgattgta gctgctgatg acggggtaat gccacaaacc attgaagcta ttaaccattc
     4381 taaggcggct ggtgttccaa ttatcgttgc catcaacaag attgacaagc caggggctaa
     4441 tcctgagcgt gttatttcag aattggctga gcatgggatc atctcaactg cttggggtgg
     4501 tgagtgtgag tttgttgaaa tctctgccaa atttaacaaa aacattgatg agctgctaga
     4561 aacagtgctt ttggtagctg aggttgaaga gctaaaggct gatcctacgg ttcgtgcgat
     4621 tggtacggtc attgaggcta gacttgacaa aggtaagggt gcggttgcga cacttctggt
     4681 ccaacaagga accctacacg tacaagaccc aatcgttgtt ggtaacacct ttggtcgtgt
     4741 gcgtgccatg acaaatgacc ttggtcgtcg tgtgaaatca gctgagccgt ccacaccggt
     4801 atctattact ggtctcaatg aaacccctat ggcgggtgat cattttgcgg tctatgctga
     4861 tgaaaaagca gcgcgtgcag caggggagga gcgtgctaag cgtgcccttc tcaagcaacg
     4921 tcaaaacacg cagcgtgtca gccttgataa cctatttgat accctcaagg caggggaaat
     4981 caaaaccgtt aacgtgatca tcaaggcaga cgtgcagggc tctgtggaag ctttggcagc
     5041 ctcactcctt aaaattgatg ttgagggcgt tcgagtaaat gttgttcact ctgctgtcgg
     5101 tgcgatcaat gagtcagatg tgaccttggc agaggcttca aacgctgtta tcataggctt
     5161 caatgtgcgt ccaacaccac aggcgcgtca gcaggctgat acagacgatg ttgagattcg
     5221 cttgcatagc attatttata aggtgatcga agaggttgag gaagccatga aaggtaagct
     5281 tgaccctgag tatcaagaaa aaatgcttgg tgaggctatt attcgtgaaa cctttaaggt
     5341 ctctaaggtt gggacaatcg gaggctttat ggttgttaat ggtaaggtaa cgcgtgattc
     5401 aagtgtacgt gtcattcgtg atagcgtggt tatctttgat ggtaagctag ccagtcttaa
     5461 gcattataag gacgatgtta aggagattgg gaatgcccaa gagggtggtt tgatgattga
     5521 aggctttaat gacattaagg tcgatgatac cattgaggct tacgtcatgg aagaaattac
     5581 ccgtaaataa tcgtggtggc tagtagctta aatagcctcg tctcaagaca atagacaatg
     5641 tcaccacttg atttgaacag tcactattaa tagtatagcc atcagcctaa tagagaaaaa
     5701 ggcttgaaag tcatcaagct tttctcttgt tattgagcta ctgagagcct gtactatttg
     5761 acaatagaaa ggaagggcca tgacaaatca tcgtattgat cgtgttggta tggaaatcaa
     5821 gcgtgaggtc aacgagattt tacacaaaaa ggttcgtgat ccacgtgtgc agggtgttac
     5881 gatcacagaa gtgcaaatgc tgggcgattt gtcagttgct aaggtttact ataccattat
     5941 gagtgaccta gcttcagaca atcaaaaggc tgaaataggc ttaaaaaaag caacaggaac
     6001 cattaagcgt gagcttggta agcaattaac catgtataaa attccggatt tggtttttga
     6061 aaaggacaat tctatcgcct atggtaataa aattgatcaa ttgctccgtg agctagaaaa
     6121 gaaacagtag tcatgctgtg atcagaaaat gcctaccagg ctttggcaaa aaactcaagt
     6181 ctggtaggca tttttgtatt attatttttg gggttcgtac tcttttttta tggtatcaat
     6241 gatttggtat tgtgctgtct tggcctcttc aatcgggtaa ataggataaa catggttcat
     6301 cttttccccg acaaatagct ggtgcttatg tcctttttgt tttaacatac catcaaattt
     6361 tgtaatgtct gggtagaaga tttcatgagt tcctacaaac atggtgatag gtgctaggtt
     6421 gcttgtatct ccatagatag ggctaacata agggtgctta gtgttatttt ccccgcgtcg
     6481 tgcccagata tcacctacta tgcgcagtcc ccgagccgat aagataggat cagaggcttc
     6541 gtaatttggg atctctggat ttgatagggt gacatcaagc caaggtgaga gcaggataat
     6601 gtccttaggc tgcttaatat cttcattttt caatgctagt gccaaaccta gtgccagacc
     6661 gcctccggct gagtctccca tgatggtgat attgttagca ttgttattag tgctttttag
     6721 aatatcctga taaagactaa ctaatcttgg catagcgaca tcataggtat aggtcggagc
     6781 ctttgggtaa atcggcaata caatcttagc atcaaggcta gttgacaagg ttttgagcat
     6841 gtcaatatgg tatgaggtcg ggttgtttag gtaggagcca ccatgcagat agagaatgac
     6901 cttttgattt gatggattag tagagttttc attccagctg tgaacctgca tgttgtctct
     6961 atactctgtc tttaatgttc cgttgacctc attttgagtg agattaaagc cttgattgct
     7021 cttttcacca gctgacttga cgtagttgta gaaggtattc tcatcctgct cggcataata
     7081 gcttttgtct cgtttaagcc aaaaatattg ctcaataaac cagcttttcc aggatcgcgt
     7141 gctggcctga acgattgttt ggctacctat agctgtgagt agaagggcta gtagaattag
     7201 ctgtctttta agatacgtca atgttttctc cttaatcatt acagtattac tgtcatatag
     7261 taatatacaa ggactcattt tgtcaatata aagttaatca gataagactg gaaagttcag
     7321 actattaaaa gctagctgct gactttagct gtcagtcctt ttttgacgct gtttctcata
     7381 aagagacctt ttttagttat tatttgttta caaacgtaaa caaataagct atacttaata
     7441 aaaccgtaga tgaaagagag gtagcaatat ggatacgata tctgatgcag aatgggaggt
     7501 tatgcgtgtt gtttgggcta atgggagcat gaagagctct gagattattg ctattcttca
     7561 tgaaaagcac cattggtctg attctaccgt taagaccttg attggacgct tggttaagaa
     7621 aaaagcccta agggctgata gacagggacg gtcctatatt taccagtcct tgcttgatca
     7681 ggacaggcga cagcttgcta tgctacgaga gaggcttgat ggcatgtgtc aacgccacca
     7741 tagccgcttg ttgctggcat tactaaagga taccccaatg accctggaag atattcaggc
     7801 ttttcagttg ctcttagagg ctaaaaaagt cggagcagta tcccatgtaa ggtgtgattg
     7861 tgtgccagga caatgtcatt gtcagaaaaa ggagaggata tgattgttaa agagacctat
     7921 ctattagagg gaatgcactg cacctcctgt gctctagcga ttgaacaggc tgttaagcaa
     7981 ctgccaggtg ttgagggggc agctgttgat gtgacgactg agaagctatc agtgagctac
     8041 tcaactgaca gcctcagctc agcagagctc attcaagcag taagaaaggc aggctacaga
     8101 gcagagctgc ttgatgagac caatatgaga gggcaactag agcgcctaga ggagcaggct
     8161 agcaatgaat ggtatcgctt tctgtggtct gctctcttta gtctgccgct gctatacctt
     8221 gcaatgggac ctatgcttgg attggtgctg ccggtcgctc tagcacctca gtcgcatgct
     8281 ataagctatg gtcttgttca gcttttgctg accctgcctg ttcttttctt gaatcggcag
     8341 tactatgaaa atggctttaa ggcattgata aagaagcggc ctaatatgga ttcgcttgtg
     8401 accttagcca ctagctttgc ttttatttac agctcatata gctgttttaa gattgtagct
     8461 ggagctgctc aatttgctca ccagctttat tttgaatctg ttgtggttat tctgaccttg
     8521 attacccttg gcagctattt ggaggggcgt accaagggac gggcctcgca ggctattcag
     8581 aagctaatgt ccttaagggt aactgatgtc agggttattc gtgagggagc acttcagctt
     8641 attcccttag agcaggtgac taatgaggat atttgcttta ttcaaccggg tgaacgggtg
     8701 gctgttgatg ggctgatagt agaggggcag tctacggttg atgagtccat gctaacagga
     8761 gaaagcctac cagttgataa ggtgacaggt gatagtgtgt ttgctggcac aatcaatggc
     8821 caaggagcgc taagggtaaa gccctctagg cttggcaatg acaccttgct ttcacagatt
     8881 attgagctgg tggagcaagc acagcaagcc aaggctccga ttgctgcact tgctgatagg
     8941 gtatcaggag tctttgtccc tatcgtatta agtttatccc tgctgagctt tcttttttgg
     9001 ctctttgtta tgagagagag ctttgatttt gccctgacaa tagctatagc tgttttgatt
     9061 attgcttgtc cctgtgctct gggtctagca actcccaccg cgattatggt tggctcaggt
     9121 cgtgcagctg agcagggatc ctttttaagg gaggagatat tttagagaag gcttatcagg
     9181 tgcggacaat tgtttttgat aaaacaggaa cgctgacaga gggtcaggct cagctacagc
     9241 ggatcatccc ccttgctgct agtgagaagc agggacttca ggaggtggct tccttagagc
     9301 agtattcgca gcaccctctt ggagaagcgc ttgttagagt agcacaggaa aagggctatg
     9361 acttgctggc tgtgactgat tttcaatcgc ttgtgggctt gggtgtcact ggtgtgattg
     9421 accagcatcg cttagctgtt ggcaatagtg agctgatgtc acagcagggg attgcgataa
     9481 gcgctgctca gacctatgcc gagcaagctg ccttaaaggg gcaaaccgta gtgtattatg
     9541 ccaaggataa tcagctatgt gctttattgc tgattgctga taggctaaag gctgacagta
     9601 aggcagctat aagggccttg caggatttag gtcttcaaac ggttatgcta acaggagata
     9661 atgccctcac agctcaagcg attgctaatg aggtgggaat tgatcaggtc tttagtcagg
     9721 tgctgcctgc tcaaaaggcc cagattatcg cggatttgaa ggctagcgga cagctggttg
     9781 ctatggttgg tgatggaatc aacgacgcac cggccttgac cctagcggat attggaatct
     9841 caataggctc aggtacggat attgcgattg aggcggcaga tgttatcctg atgacctcag
     9901 cagtgcgtga tgtggtggaa tgcctagagc tcagtcgtca aaccatcaga gtggttaagc
     9961 aaaatttatt ttgggcgttt agctataata gcctaatgat ccccgttgct atgggtatcc
    10021 ttcatgtctt tggcggccct ctattaagcc caatgctggc tggctttgcg atgagcctta
    10081 gctcaatatc agtggtgtta aatgctttgc gattaaggca taaaaaatgg taaaggctct
    10141 caccgacctt accgtcagta tagtaaagct aaaggcctgc gccgacaaaa ggcataaaca
    10201 aaacaaagag caggaataaa aaagcagatc atttattggt taaggctacc agaagccacc
    10261 aagtgctata gcaacctgat atggcaaata gcaccgaaaa atatgacagg tataggataa
    10321 ccttacatta tcgctgagag atttaaaggt gctattattg ttaccgatca taggtttctt
    10381 catattgaca ccacttttta gctgttaata tgagaagacg gtttaagcag gcttcgtatt
    10441 ttggttgaga atagactaag tgaattgttc tatgacaaag aaaggataac aggctttatg
    10501 agttaatagg gtgtcattag ctcccggctt attttttgac taacatcaac agaagagcag
    10561 taaaccaagc aagggtttgc tgttttttct tgctcagcat gagacggaaa aagtgagcat
    10621 aacaagcaat caaaaagagc agctgaatca tggtcaggca aagacagcat gcgaagaaca
    10681 agctgaatag tgactccaaa agaagggctg gcgctgatag tcttgatctc atagaggcct
    10741 ttatggtttc cgctgataaa cgggggtatt gctcacaaca tgattaggta aaaaagagca
    10801 cgatgatgtc tatattaaca ttatgtggtt attattgagc gtcatttaaa tataataata
    10861 gaaaaaat
//
LOCUS       DARYXS010000070        10692 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.071, whole genome shotgun sequence.
ACCESSION   DARYXS010000070 DARYXS010000000
VERSION     DARYXS010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10692
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.071"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..424)
                     /locus_tag="TV193_001460"
     CDS             complement(<1..424)
                     /locus_tag="TV193_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513642.1"
                     /translation="MVKLSKRSKIAMSFLIVFCGIFFVAQKRFGSSDQSFTVRPDADF
                     YIVGYHNIEGYQLTNEQPQKISDAKLEVVKGQINQVVKRAELSNRYLVFSEEGPPLGA
                     IGRLIALDFQKGNVTYHPTADYAFTSSGVSPDYYFTSTA"
     gene            1025..1843
                     /gene="proB"
                     /locus_tag="TV193_001461"
     CDS             1025..1843
                     /gene="proB"
                     /locus_tag="TV193_001461"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEL1513643.1"
                     /translation="MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLM
                     NKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTT
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDR
                     LSAIVARITRADLLIMLSDIDGLFDKNPTIYEDARLRSHVTEITEDIIASAGGAGSRF
                     GTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA"
     gene            1843..3090
                     /locus_tag="TV193_001462"
     CDS             1843..3090
                     /locus_tag="TV193_001462"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEL1513644.1"
                     /translation="MTIEQLGQRAKAASRALVSLTTKDKNQFLAFLAEELVAQTDMIL
                     TENAKDLAKAAEHGISEILCDRLRLTADRIHAMAQGVRQVADLADPIGEVIKGYTNLD
                     GLKITQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALYSNMALVRLI
                     RNALEASAITPDAVLLVEDTSHAVAEELMQATDYIDVLIPRGGARLIQTVKEKAKVPV
                     IETGVGNVHIYVDEAADLEMAVKVVINAKTQRPSVCNAAESLIIHEKVGATFIPMLEA
                     AISKVQQVEWRADEQAKALFSKAVLATEEDYAAEFLDYIMSVHLVSSLDEAISWINQY
                     TSHHSEAIITANINAAERFQDLVDSAAVYVNASTRFTDGFVFGLGAEIGISTQKMHAR
                     GPMGLEALTSSKYLINGNGQIRS"
     gene            3110..3526
                     /locus_tag="TV193_001463"
     CDS             3110..3526
                     /locus_tag="TV193_001463"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513645.1"
                     /translation="MTRDLKKQETIRDLKTLAFKLESVIEALKELKRWGFFDLFDNGI
                     LTSWVKRQKISAINESLGDVRNLVCRYQKELKVSELRLPSSLSHTRQDKIFDIWLDNS
                     VTDFRVLKETKQVLESAELLYEAVQQALSHLDVKDS"
     gene            3629..4579
                     /gene="rsmH"
                     /locus_tag="TV193_001464"
     CDS             3629..4579
                     /gene="rsmH"
                     /locus_tag="TV193_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEL1513646.1"
                     /translation="MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSL
                     LGDKGHLYCFDQDQKAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTEIDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYG
                     EDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADASIQRAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPD
                     ELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK"
     gene            4583..4906
                     /gene="ftsL"
                     /locus_tag="TV193_001465"
     CDS             4583..4906
                     /gene="ftsL"
                     /locus_tag="TV193_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEL1513647.1"
                     /translation="MVNEKRTQAVSKALQKRIRTFSRVEKAFYATLILTAVTMAVSII
                     YLQSRKLQLQQHITQLNRQISDKRTELNNAKQEVNELSRRDRIVDIAGKAGLSNRNDN
                     IKKVE"
     gene            4910..7165
                     /locus_tag="TV193_001466"
     CDS             4910..7165
                     /locus_tag="TV193_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1513648.1"
                     /translation="MTKWQRYFLDYVVRDRKTPVQNRLRVGQNMMLLTIFIFFIFMIN
                     FMIIIGTDQKFGVKLSDGAKKVYQETVSVQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSATGEKLFVQPSQYDKVAQILKEQLGMEEKDVIKQLKQKGLFQVSFGPSGSGIS
                     YSTMTTIQKAMEAAKIKGIAFSASPSRMYPNGTFASELIGLASLEENKEDGTKSLVGK
                     MGMEAAFDSILSGEDGIITYQKDRNGNTLLGTGKTVKKPVDGKDVYTTLSEPIQTFLE
                     TQMDVFQSKAQGELASATLVNAKTGEILATTQRPTYNADTLEGLNSKSYSWQNILHQG
                     QFEPGSTMKVMTLAAAIDEKVFNPDETFSNANGLTIADATIQDWAINEGISTGQYMTY
                     AQGFSFSSNVGMTKLEQKMGNDKWMNYLTKFRFGFRTRFGLENEDPGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNDGVMLEPQFVSRIYDPNTDTYRVSDKEIVGKPVS
                     QKAASETRKYMINVGTDPQFGTLHLKSSGPVVKVGQLPVAVKSGTAQIATKDGTGYLD
                     GGLTNYIYSVVAMVPADEPDFLMYVTLKHPEHWAMVFWQDIINPVLEEAYLMKDTLDK
                     PVAVDTSHEATYQLPDIVGQDTGKSADELRRNLVHPIVLGNGSKIKKVSKKAGTNLAA
                     NQQLLILSNHFDEMPDMYGWTKANVATFAKWTGIDIKYKGSSSGRVVKQSVDVGKALK
                     KVKKITITLGD"
     gene            7167..8174
                     /locus_tag="TV193_001467"
     CDS             7167..8174
                     /locus_tag="TV193_001467"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEL1513649.1"
                     /translation="MFLTILAGLIAFAVTALAMPHFIRLYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATSLSFVFALVYFRDGQSLGLISGILLIVLIYGIIGFLDDFL
                     KIFKQVNEGLTAKQKFTFQIVGGLVFYVIHVMPSGIDAINVFGYHWHLGFLYLCFVLF
                     WVVGFSNAVNLTDGIDGLASVSVVISLLAYGVIAYAQGQFDVLLLIGIMVGALLAFFL
                     FNHKPAKIFMGDVGSLALGAMLAAISIALRQEWTLLVIGIVYVLETSSVMLQVTYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKAAKWSEWKVDAFLWALGLVASLIVLAILY
                     L"
     gene            8257..9600
                     /locus_tag="TV193_001468"
     CDS             8257..9600
                     /locus_tag="TV193_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1513650.1"
                     /translation="MSFHDYHFKHYIQEALDELGFVEPTEVQQRLIPIVSTGRDLVGE
                     SKTGSGKTHTFLLPIFEKLKEEKEEVQAVITAPSRELATQIFEASRQIAKHSKQEIRI
                     ANYVGGTDKQRQLDKLKLSQPQLVIGTPGRIYDLVKSGDLAIHKASTFVVDEADMTMD
                     MGFLSTVDKIASALPKTIQILVFSATIPQKLQPFLRKYLTNPVIEQIKTETVIADTID
                     NWLLSTKGRDKNEQILATLKAIQPYLAMLFVNTKERADDLHAFLAANGMKAAKLHGGI
                     PPRERKRIMNQVKNLAFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITFYQPSDDSDIKELEKLGITFIPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKIKPGYKKKIQWAVDEKRRKQRRAEKRAKGRAERQSRKQSF"
     gene            complement(10241..10684)
                     /locus_tag="TV193_001469"
     CDS             complement(10241..10684)
                     /locus_tag="TV193_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513651.1"
                     /translation="MVSVTLLTVAVLSLSTRFIYSTDYSDLNHKEMARLIQSRKQPVI
                     KYHDNVTINKMITYLAQAKREGILTETFLMNYIFAGEGEYLTKNSRIIADPDGGYWSI
                     LEGYEGDGGVKTGIDGVSELNIFSPESTSIGELQEAVLAWYEANK"
BASE COUNT         3021 a         2028 c         2567 g         3076 t
ORIGIN      
        1 ttgctgtaga agtgaaataa taatctggtg atactccgga ggaagtaaag gcataatcag
       61 ctgttgggtg atacgtcacg ttgccttttt gaaaatcaag agcgataagt cttcctattg
      121 cccccaaagg tggcccctcc tcggaaaaga ccagataacg atttgaaagc tctgctcgtt
      181 taaccacttg attgatctga cctttgacca cttcgagctt agcgtcagaa attttttgcg
      241 gctgctcatt tgtcaattga taaccttcaa tattgtggta accgactata tagaaatctg
      301 cgtctggcct tacggtaaat gattggtctg atgaaccgaa tcgtttttga gcgacgaaaa
      361 atataccaca aaagacaatt aaaaatgaca tagctatctt gcttcttttt gatagtttaa
      421 ccatagtgat ttattcctat aactaattaa ttgctttaga tgactgacag gctctgtcgt
      481 cctaagcccc caaactaatt gagaacaatt gagtcttggg attccaaaaa tttaaatgat
      541 acggttttcc tacttgattt ccagcctatt gatttgcgtt ccagtcttgt tgaacactgg
      601 tagcctttgc gccaatgtgc cagacagtat gcctgtgact tgttcttgct acttctgaaa
      661 cgtgttcttt ctgtcaggta ttgcgcttta cagcaaggtc tggcccttag gtagtaaata
      721 tagctgtttg cgctttcatt ttatcgtatt gtgcgttttt gtcaatagct ttagtgttgg
      781 tatatggtca ttaaaaatga caggacaatg caggaggatc agacttaaac ttacaatagg
      841 ataaagcgta gcgtggtatg tggtgtcaca aaggaaatcc tgcttggagt ggctatcagg
      901 tggattttta tatcttaggt gaatgggtag ccagtgatcc ttttttttat caagctgata
      961 ggctgattga ttttggcttc aatctaacag tcctctgggc tgttttttat gctataatcc
     1021 taatatgatg aaacgacaat ttgaagatgt aaagcgtatt gtaattaaaa ttggaaccag
     1081 ctcgctggtg cttgctaatg ggaagattaa cttagaaaag atcgaccatt tagcctttgt
     1141 gatttcaagc ttaatgaata agggaaaaga ggttattttg gtttcctctg gcgccatggg
     1201 ctttgggctt gacctgttga aaatggccaa aagaccaagt cagcttgcca agcagcaggc
     1261 tgtttcaagt gtggggcagg ttgctatgat gagcctttat tcgcaaattt ttgcccacta
     1321 tcagacgaca gtgtctcaga ttttgctgac acgtgatgtg gttgtttttc cagaaagtct
     1381 ggcaaatgtc accaatgcct ttgaaagcct gattagttta gggattgtcc ccattgtcaa
     1441 cgaaaatgat gctgttagtg ttgatgagat ggatcattca acaaaatttg gagacaatga
     1501 ccgcttatca gctatcgtag ctcgtattac aagggctgat ttgctgatta tgctatcaga
     1561 cattgatggt ttgtttgata agaatccaac catctatgag gacgcgcgct tgaggagtca
     1621 tgtgacagag attacagagg atattatagc ctcagcaggc ggtgcaggca gcagatttgg
     1681 aactggtggt atgctaagta agatccaatc agcccagatg atgtttgagc atcaggggca
     1741 aatgattttg atgaatggtg ccaaccctag agacatttta agggtcttgg agggagaaaa
     1801 gctaggcact tggtttaaac agatagaaag aggtgacgcg tgatgacaat agaacagcta
     1861 ggacaaaggg ctaaggcagc tagtagggcc ttggtatcct tgacaacgaa ggataaaaat
     1921 caatttcttg cctttttggc tgaggaatta gtggcccaga cggatatgat tttgacagaa
     1981 aatgccaagg atctggctaa ggcggctgag catgggattt cagagattct gtgcgatcgc
     2041 ttacgcctga cagcagatcg tatccatgcg atggctcagg gcgtcagaca ggtggcagac
     2101 ttggctgatc ccattggcga agtgattaag ggctatacaa atctggacgg cctgaaaata
     2161 acccaaaagc gtgtgccttt aggtgttatt gcgatgattt ttgaaagccg ccctaatgtt
     2221 tctgttgacg cctttagctt ggcctttaag accaataatg ccattattct tagaggtggc
     2281 aaagatgctc tctactctaa tatggccttg gtcaggctta tcagaaatgc cttagaggca
     2341 tcagctatta cgccagatgc tgttttgctg gttgaggata cctctcatgc tgtagctgag
     2401 gaattgatgc aggcaacgga ttatattgat gtcttgattc ctcgtggggg tgccagatta
     2461 attcaaacgg tcaaggaaaa ggctaaggtg ccagtcattg agacgggggt tggcaatgtt
     2521 cacatttatg ttgatgaagc agccgatcta gagatggctg ttaaggttgt gattaatgct
     2581 aagacgcaaa gaccaagcgt ctgcaatgct gcagaaagcc tgattattca tgagaaggta
     2641 ggagcgacct ttattcccat gcttgaagca gccatcagca aggttcagca ggtggaatgg
     2701 cgagcagatg agcaggcaaa agccttgttt agcaaggctg tattagccac agaggaagat
     2761 tatgcggctg aatttttgga ttatatcatg tctgttcatc tggtttcctc tcttgatgaa
     2821 gctatttctt ggattaatca gtataccagt catcattcag aagccatcat cacagctaat
     2881 atcaatgctg cagagcgttt tcaggatctg gttgactcgg cagctgttta tgtgaatgcc
     2941 tcgacacgct ttacagatgg ctttgtcttt ggtctaggag cagaaattgg catttccaca
     3001 caaaaaatgc atgctcgtgg cccgatggga cttgaggcct tgaccagcag taaatacctg
     3061 atcaatggaa atggccagat tcggagctag ctgctaagga ggtaggctta tgacaaggga
     3121 tctaaagaag caagaaacca tacgagacct aaagacatta gcttttaagc ttgagtctgt
     3181 cattgaggca ttgaaagagc ttaagaggtg gggatttttt gatttgttcg acaatgggat
     3241 actaacaagc tgggtaaaaa ggcaaaaaat cagtgctatt aatgagagcc taggggacgt
     3301 gagaaatctg gtctgtaggt atcaaaagga gctgaaggtt agtgagttgc gcttgccttc
     3361 tagcttatct catacaagac aggataagat ctttgatatt tggctagata attcggtgac
     3421 agattttcgg gtgttaaagg agaccaagca ggtgctcgaa tcggctgagc tgctgtatga
     3481 ggctgtgcag caagctctta gtcatcttga tgtcaaggat agctaagcca aaaaaagtaa
     3541 gataaagagg gactttctta ggccttgaaa gcccttttct cttacttttt gatttataaa
     3601 ccctttgaag tatggtacaa ttagagctat gacaaacgaa tttcatcatg taactgtact
     3661 tcttcatgaa gctgttgata tgctggatat taagccagat ggtatttatg tagatgcgac
     3721 ccttggtggc tctgggcact cagcttattt gctgtctctg cttggtgata aggggcactt
     3781 gtattgcttt gatcaggacc aaaaggctat tgatcacgcg caggagcagc tcaagcccta
     3841 tattgacaag ggacaggtga cctttattaa ggacaatttt agacacctta aggcacgctt
     3901 gctggagcat ggggttacag agattgatgg gattttgtat gatttagggg tttctagtcc
     3961 gcagttagat gagagagagc gtggcttttc ttacaagcag gacgctccct tggacatgcg
     4021 aatggatagc caggcggctt tgacagccta tgaggttgtc aatacctatg atttcaatga
     4081 cttagttcgg atctttttta aatatggtga ggataagttc tcaaagcaga ttgctcgtaa
     4141 gattgagcag gcgagagcca ttaagccaat cagcaccacc acagagctgg cagcattgat
     4201 caaatcagct aagccagcca aggagctcaa gaaaaaagga cacccagcca agcaaatctt
     4261 tcaggctatt cgtattgagg tcaatgatga gcttggtgct gctgatgcgt ctatccagcg
     4321 ggcgatagag ctgctagccc ttgatggccg tatctcagtg attacctttc attctttgga
     4381 ggatcgtctg acaaagcact tgtttaaaga agcaagcaca gctgatgctc caaagggact
     4441 tccctttata cctgatgagc tcaagcctaa gcttgaattg gtttcgcgta agccgatttt
     4501 accaagtcaa aaggagctaa tggctaacaa tagggcacat tcagccaagc tacgagtcgc
     4561 aagaaaagtt cggaaataga ttatggttaa tgaaaaaaga actcaggcag tttcaaaagc
     4621 cttgcaaaaa agaattagaa ctttctcgag ggttgagaag gctttttatg ctacgcttat
     4681 cctgacagca gtaacgatgg ctgtaagcat tatttacctg caaagccgta aattgcagct
     4741 ccagcagcat atcactcagc tcaataggca gatctcagat aaaaggacag agcttaacaa
     4801 tgccaagcaa gaggttaatg agctgtcgcg acgtgaccgc attgttgata ttgctggcaa
     4861 agcagggctt agtaaccgaa atgataacat taagaaggtc gagtaagcta tgacaaaatg
     4921 gcaaagatat tttttagatt atgtggttcg tgatcgaaag acacctgttc agaaccgctt
     4981 gagggtgggg caaaacatga tgctcttaac catctttatt ttcttcatct ttatgattaa
     5041 ttttatgatc attatcggga cggatcagaa attcggtgtt aagctatcag atggagccaa
     5101 aaaggtttat caagagacgg tttctgttca ggccaagcga ggcacgattt atgatcgcaa
     5161 tggcacagct atcgctgtgg actcgacgac ctatagcatt tatgccattc ttgataagtc
     5221 ctttgtgtca gcgactggcg agaagctttt tgttcaaccg tctcagtatg acaaggttgc
     5281 tcaaatcctc aaggagcagc tgggtatgga ggaaaaggac gttattaagc agcttaagca
     5341 aaaaggtctt tttcaggttt cctttggtcc gtctggctca ggtatttctt atagcacgat
     5401 gacaacgatc caaaaggcta tggaggcagc taaaatcaag gggatcgcat tttcagcaag
     5461 tcctagccgt atgtatccaa atgggacctt tgcttcagag ctgattggtc ttgcttcact
     5521 tgaggaaaac aaggaggacg gtaccaagag cctagttgga aagatgggca tggaggcggc
     5581 ctttgatagc atcttatctg gggaagatgg aatcatcact tatcaaaagg atagaaacgg
     5641 taataccctg cttggaacag gaaagacagt gaaaaagcca gttgatggta aggacgttta
     5701 taccaccctg tcagagccta ttcaaacctt tctagaaacg caaatggacg tctttcagtc
     5761 gaaggcgcaa ggagagcttg ctagtgctac tctagtaaat gctaagactg gtgaaatctt
     5821 agcgactact caaagaccaa cctataatgc agacaccttg gaggggctaa acagcaaaag
     5881 ctatagctgg caaaatattc tccatcaggg gcagtttgag cccggctcaa ccatgaaggt
     5941 tatgactctg gcagctgcta ttgatgagaa ggtctttaat cctgatgaga cctttagcaa
     6001 tgcgaatggc ttaaccattg ctgatgctac cattcaggat tgggcgatta acgaagggat
     6061 ttctacaggg cagtacatga cctatgctca aggcttttcg ttttcaagta acgttggcat
     6121 gaccaagcta gagcaaaaaa tgggaaatga caaatggatg aactacctaa ctaaattccg
     6181 ttttggattc cggacacgct ttggcttgga aaatgaagac ccaggtattt tcccttctga
     6241 taatattgtt acccaagcaa tgagcgcttt tggtcagggg atttcggtga cgcaaattca
     6301 aatgcttaga gcctttacag ccatctctaa tgacggtgtg atgctagagc ctcaatttgt
     6361 tagtcgcatt tatgacccaa atacagatac ttaccgggtg tcagacaagg agattgtcgg
     6421 aaagccggtg tcccaaaagg ctgccagtga aacacgaaaa tacatgatta acgttgggac
     6481 tgacccacaa tttggaaccc ttcatttgaa atcatcaggt ccagtggtta aggttggtca
     6541 attaccagtt gctgtcaagt cagggactgc gcagattgcg actaaggacg gtacaggtta
     6601 tttagatggt ggcttgacaa actatattta ttcggtggtt gctatggtgc cagctgatga
     6661 gcctgatttt ctgatgtatg tcacactgaa gcacccagag cattgggcaa tggtgttttg
     6721 gcaggatatt atcaaccctg ttttagagga agcctatttg atgaaggata ctttagacaa
     6781 gccggttgct gtagatacca gtcacgaggc tacttatcag ttgcctgata ttgttggcca
     6841 agatacagga aaatcagctg atgagctacg cagaaatctg gttcacccta ttgtccttgg
     6901 caatggcagc aagattaaaa aggtatctaa aaaggcaggg accaatctag ctgctaacca
     6961 acagcttctg attttatcaa atcattttga tgagatgcct gatatgtacg gctggactaa
     7021 ggctaatgtg gctacctttg ctaaatggac tggcattgat atcaagtaca agggatcaag
     7081 ctcgggacgt gtcgttaaac agagcgttga tgtcggaaaa gcgctcaaaa aagtcaaaaa
     7141 aattaccata actttaggag attaacatgt ttttaaccat tctagcaggt ctgatagcct
     7201 ttgctgtgac tgcccttgcc atgcctcact ttataaggct ttaccagttg aaaaaaattg
     7261 gggggcagca gatgcatgag gacgttaagc agcatttggc taaggctgga acacctacaa
     7321 tgggaggaac agtttttctt cttgttgcta caagcttatc ctttgtgttt gctttagtct
     7381 attttcgaga tggacaaagc ctaggcttga tttcggggat cttgttgatt gtattgattt
     7441 acgggatcat aggcttttta gatgatttct taaagatctt caagcaggtt aatgaaggcc
     7501 ttactgccaa gcaaaaattc acgtttcaga ttgttggagg cctggtcttt tatgtgatac
     7561 acgtcatgcc aagtggtatt gatgcgatta atgtctttgg ttatcattgg catttgggct
     7621 ttttatacct atgctttgtt cttttttggg tggttggctt ttcaaatgcg gtcaacctga
     7681 cagacggtat tgatggtctg gcctcggtat ctgttgtgat tagcctgctg gcctatggtg
     7741 ttatcgctta tgctcaggga caatttgatg ttttgctctt gataggtatc atggttggtg
     7801 ccttgctggc ctttttcttg tttaaccata agccggccaa aatttttatg ggtgatgttg
     7861 gaagcttagc cttaggagca atgctagcag cgatttctat tgcgcttcgt caggaatgga
     7921 ccttgctggt tattgggatt gtctatgttc ttgagacaag ctcagtcatg cttcaggtta
     7981 cttactttaa atacaccaag aaaaaatatg gtgaaggccg tcggattttt aggatgactc
     8041 cttttcatca tcatctggaa ttaggcggct tgtccggtaa agcagccaag tggtctgaat
     8101 ggaaggttga tgccttccta tgggctcttg gtcttgtagc cagtctcatt gttttagcga
     8161 ttctttattt gtaagcggct ggggcagtgc ttgaggcacc gccttttgct catctcaagc
     8221 actaatagta ttatcagaaa gaaaacgagg taaataatgt catttcacga ttatcacttt
     8281 aagcattata ttcaagaggc cctagatgag cttggctttg tagagccaac agaggttcag
     8341 cagcgtctta tcccgattgt cagtacagga cgagacttag tgggtgagtc aaagacaggc
     8401 tcaggaaaga cgcatacctt tttgctgcct atttttgaaa agctcaagga ggaaaaagaa
     8461 gaggttcaag ctgtgattac agcacctagc cgggaactag caacacagat ttttgaggcc
     8521 agcaggcaaa ttgctaagca ttctaagcag gagattcgta ttgctaatta cgttggaggg
     8581 acagacaagc agcgtcagct tgacaagtta aagcttagtc agccccagct tgtcattgga
     8641 acgccaggtc gtatctatga tctagtcaag tcaggagatt tagccattca taaggcctct
     8701 acctttgttg ttgatgaggc tgatatgaca atggatatgg gctttttaag cactgtggat
     8761 aagattgctt cagcactgcc aaagactatc caaatacttg tattttcagc aaccattcca
     8821 caaaagctac agcccttttt aaggaagtat ttgaccaatc ctgtcattga acagatcaag
     8881 acagaaaccg ttattgcaga tacgattgac aactggctgt tatcaaccaa gggacgcgat
     8941 aaaaatgagc aaattttggc gactctaaag gctatccagc cttatctggc catgcttttt
     9001 gtcaatacca aggagagagc tgatgactta catgcctttt tagcagctaa tggtatgaag
     9061 gcagccaagc ttcatggagg tattcctcct agagagcgca agcgtatcat gaatcaagtc
     9121 aaaaacctgg catttgaata cattgtggca acggatttgg cggcgcgtgg tattgatatt
     9181 gagggggtta gtcatgtgat taacgacgcc attcctcaag acctatcctt ttttgtgcat
     9241 cgtgtggggc ggacaggtag aaacggcctg ccagggacag ccattacctt ttatcagcca
     9301 agtgatgatt ctgatatcaa ggagctggaa aagctaggca ttacctttat accaaaggtt
     9361 ttaaaaaatg gtgagtttca ggatacttac gatcgtgatc gtcgccagaa tcgtgaaaaa
     9421 gcttatcaga aattagacac tgaaatgatt ggcctggtta agaaaaaaaa gaaaaaaatt
     9481 aaaccgggct ataaaaagaa aattcaatgg gcagttgatg aaaagcggcg caagcagcga
     9541 cgagcagaaa aacgtgccaa gggacgagca gagcgtcagt ccagaaagca aagcttttaa
     9601 gacaggtgct tggtaaagat catccgttca agaaaaatta gatcaaaaag tttttagcga
     9661 tcattctaag ctgatatgaa cagaatcctt gacagagctg agtcaaggaa ctgtgattag
     9721 gtcccaaagc tgtttaggga ttgtttttaa aggcttcaac tctgttcagt gtcccatgtc
     9781 aaatggtcct gtcgttgcgt gcaaggattt caatctacgc tcccgcaaaa ggtgtgataa
     9841 aagtattgtt acatttgaaa ttgtcgaacc tacttcaatt gttacagcaa ctatctttga
     9901 agcgtggcaa ctaaaaccag ctattaacaa ctaaagccgc acctttggct gtcagaatag
     9961 tgattgaaat taacgggttg atacgctttg acacaccagc cttaaattac ttcctctgtg
    10021 ggagtgtaga ttaaggtgta ttaatgtttg aggaggagct tgctcctctt ttttgcttgt
    10081 tcagctcaat gtctctctga aggctatggt tttggttaga tggtaagcac taaaaaacct
    10141 tataagcatt gagcatgggt ctgaccattt caatgcctat aaggcctatg attagctaat
    10201 attagctatt atatgaagca gtcggttaac taagctgcgg ttacttatta gcctcatacc
    10261 aggctagcac cgcttcttga agctctccga tgctggtaga ttctggacta aagatattga
    10321 gctctgagac gccgtcaata ccagtcttaa caccgccatc tccctcataa ccttctagga
    10381 tactccaata ccctccgtca ggatcggcaa taatccttga atttttagtc aggtactcac
    10441 cctctccagc gaaaatataa ttcatgagga aggtctctgt cagaatgcct tctcttttag
    10501 cctgagctag gtaagtaatc attttattaa tggttacatt gtcatgatac ttaattactg
    10561 gttgttttct tgactggata agacgtgcca tctccttatg atttaaatca gaataatcag
    10621 tggagtagat aaatcttgtt gataagctta aaacagctac tgttaacaaa gtaaccgata
    10681 ctattgcctt tt
//
LOCUS       DARYXS010000071        10519 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.072, whole genome shotgun sequence.
ACCESSION   DARYXS010000071 DARYXS010000000
VERSION     DARYXS010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10519
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.072"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(649..1665)
                     /gene="adhP"
                     /locus_tag="TV193_001470"
     CDS             complement(649..1665)
                     /gene="adhP"
                     /locus_tag="TV193_001470"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEL1513652.1"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTL"
     gene            complement(1868..2920)
                     /locus_tag="TV193_001471"
     CDS             complement(1868..2920)
                     /locus_tag="TV193_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEL1513653.1"
                     /translation="MKAATYVAPGQLELIDQPKPEILAPTDAVVRLLKTTICGTDLHI
                     LGGDVPETTHGTILGHEGIGIVESVGSAVNNFKVGDKVIISCITACNTCYYCKKGIPA
                     HCESGGWILGHLINGTQAEYVHIPQADGSLYHAPKTVEDDALVMLSDIFPTSYEIGVQ
                     SAKVKPGDTVCIVGAGPIGLAALLTAQFYSPAKLIMVDLSESRLEAAKRFGATDTICS
                     GDLDDIVKKVHELTDGRGVDVAIECVGYPATFDICQKIIAIGGHVSNVGVHGKPVSLD
                     LQDLWIKNITMSTGLVNANTTEMLLNVLKSGKIDATKMVTHHFKLSEVEKAYEVFKNA
                     GSNNALKVIIENDITA"
     gene            complement(3415..6057)
                     /gene="adhE"
                     /locus_tag="TV193_001472"
                     /gene_synonym="adhC"
     CDS             complement(3415..6057)
                     /gene="adhE"
                     /locus_tag="TV193_001472"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEL1513654.1"
                     /translation="MTEKNSTVETTSVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPAAWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESRTDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTKIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
     gene            complement(6478..8259)
                     /locus_tag="TV193_001473"
     CDS             complement(6478..8259)
                     /locus_tag="TV193_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEL1513655.1"
                     /translation="MRIKWFSFIRVTGLLLVLLYHFFKHTFSGGFVGVDIFFTFSGYL
                     ITALLIDEYVSKQTIDVVAFFRRRFYRIVPPLVLLILLTIPFTFLVKSDFIAGIGQQI
                     AAALGFTTNSYELLTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGLLVWLLAKKGYSQ
                     KKFRGILFLISSAVFTLSYFSMFIRAFFVSDFSSVYFSTLSHSFPFFLGAMFATMTGI
                     KDTTVRFQKNVKLWPRLHVIGVMAGAFALLLFLTLVLDFNHIFTYLFGFVLASLFASV
                     MIYAARVLSDQTPTWQEPLLVTYLADISYGIYLFHWPFYIIFTQLMSNWLAVILTVFF
                     SVVFSTLSYYIIEPLIQGKTPQLFGLAIDCNPYKKWLSGLALGLFLLMVGTCLTAPRV
                     GNFETQLLVDSLQQSQSNLNKTHTLAAGDAHALSDVSIIGDSVALRSSDAFSKLMPTA
                     QLDAAVSRNFSEAFELFENHIQSKSLSKTTVLAVGVNSLYNYAQDIQGFIYALPKGHR
                     LVIVSPYDAKNAAQVAEAREHLLQLAKKYSYVTVADWYKAAVENPNIWYGSDGVHYNN
                     DAKLKGADLYVSTIQAAVERAAKKDAK"
     gene            complement(8256..8657)
                     /locus_tag="TV193_001474"
     CDS             complement(8256..8657)
                     /locus_tag="TV193_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513656.1"
                     /translation="MKAIINNIQKWQITRTKLEIISVLVIIVCGLSVFTLTISSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFNKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            complement(8663..9121)
                     /locus_tag="TV193_001475"
     CDS             complement(8663..9121)
                     /locus_tag="TV193_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEL1513657.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSFDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            complement(9362..10369)
                     /gene="ruvB"
                     /locus_tag="TV193_001476"
     CDS             complement(9362..10369)
                     /gene="ruvB"
                     /locus_tag="TV193_001476"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEL1513658.1"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGSPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKTIK
                     T"
     gene            complement(10403..10501)
                     /locus_tag="TV193_001477"
     CDS             complement(10403..10501)
                     /locus_tag="TV193_001477"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEL1513659.1"
                     /translation="MFKKYQYYLFLAALFLLHSAQLLSDIDWWRVG"
BASE COUNT         3200 a         2357 c         1868 g         3094 t
ORIGIN      
        1 tattcgggac acaacatttt tcatctatat tttaaatcat actaccttgt tactaaaaac
       61 gtagataata atttagctta taacccatgt ttttagcaat atgttatgtc attattcttt
      121 tttcctacag tgcttcctaa aatttgtgaa gacgaattgt caaattaagt gcaacgcttt
      181 tccataaaag agtttataag gtagtttcca gttaggacat cttctagaac gatcatttca
      241 tttatcttcc cactcttata tgatagagct ctcaatatca gtcaagtcag ttcctttagg
      301 aaactactct ttgattaacc cattggtatt ttcatttgtc ctacgttatc aaggggtgtg
      361 aggagcagag aaataaactt ctagattgag ttcctgtgtt aatctctaat attgttcaaa
      421 cccagtatct ctatcagagg ttacaatatg tccaactttc tctggtactg tctttcaagg
      481 ggcaatcatg gtattaataa ctagctggct cttttacatc tttagatacc aagctttttt
      541 taccagttag tttcaccaaa aaagccctta gaaaattaat tctaaggact ttattcatca
      601 tttgggacaa tcagcttgtc tggctgctga ctttttctga aatcagcctt aaagcgtgaa
      661 atccaatacc tttcttcctt gaatgagacc acgttccatt tcgtcaaaga cttctggagc
      721 agtctcaact ggaacctttt ctacaactgg cacaaccaga ccttctgcac caaaggcaaa
      781 ggcttcttcc aagtctttac gagttcccac aagtgatccg actaccttga ttccgtctag
      841 gacagtcttt acgatagata attccatgta ttctgatgga agtcctacag caacaacagt
      901 tcctcctgca cgcacactat caatagcttg gttaaaggct actttagaaa cagcggttac
      961 cacaacgcca tgagcaccac ctgttttttc ttggatatag ccggcaacat cttcgatttc
     1021 tttaccattg acaacgatat ctgctccaac ctccttggcc agctctagct tatcattgtt
     1081 aatgtccact gctacgacat gagcattgaa aaccttttta gcatactgaa cagctaggtt
     1141 accaagtcca ccggcaccaa agataacaat ccattgtcct ggagcggcac ctgcttcttt
     1201 gatagcctta taggttgtaa cgcctgcaca ggtaattgat gatgcttgag ctgggtcaag
     1261 accatctggc actttcacag catagtcagc tgtaacaact gcatactcac tcatcccacc
     1321 atcaactgaa tagccagcat ttttgactga acggcataga gtctcgcgac ctgttgtaca
     1381 atattcacaa tgaccgcagc cttcaaagaa ccaagcaatt gatacacgat caccaacctt
     1441 taaggaggta acgccttcac ctagcttttc gacaataccg ataccttcat gaccgaggat
     1501 acgccctgga acctgaccaa aatcaccatg cgcaacatgc aagtcagtat gacatacgcc
     1561 acaatattct actttaacaa gagcttctcc atgaccgatt gatggtacat catgctctac
     1621 aacctctaca ccactgctgg tttggttaac aactacagcc ttcataggat gcctccaatt
     1681 tctaagtctc ggtttatcta tttttgcaac cgtttacaat ttgtattgta tactttttca
     1741 caaggtttgt caaccaattt cttgaaagtt ttctgaaaat aaacttaacc agttaagttg
     1801 gctaaaaaac agcatctaga ccattccaaa tgctgttgtc acttttatct atttatacct
     1861 tattccttta ggctgtaatg tcattttcaa taatcacttt aagggcgtta ttactgccgg
     1921 catttttaaa gacctcatag gctttttcaa cctctgacag cttaaagtga tgtgttacca
     1981 tcttagttgc atcaatctta ccagatttca acacattcaa tagcatttct gttgtattag
     2041 cgtttactag gccagttgac attgtaatgt ttttgatcca taggtcctgt aggtccaaac
     2101 taactggttt tccatggaca ccaacgttag aaacatgccc gccaatagca ataatctttt
     2161 ggcaaatatc aaaggtagca ggatagccta cacactcaat ggcaacatca acacctcgac
     2221 catcagttaa ttcatggact tttttgacaa tatcatcaag gtcaccagag caaatcgtat
     2281 ctgttgctcc aaagcgctta gctgcttcta aacgtgattc tgacaagtca accatgatca
     2341 gcttagctgg tgaataaaat tgtgctgtta aaagagctgc tagtccgata ggacctgctc
     2401 caacgataca cactgtatca cccggcttta cctttgcaga ctgaacgcct atttcatagg
     2461 aagttgggaa aatgtctgac agcataacca aggcatcatc ctcaacggtt ttaggagcat
     2521 gataaagact gccatctgct tgaggaatat gaacatactc tgcttgtgtc ccattaatca
     2581 aatgccctag aatccagcca ccgctttcac aatgagcagg aattcctttt ttacaataat
     2641 agcaggtatt acaggctgtg atacaggaaa taataacctt atcacctacc ttaaagttgt
     2701 tcactgcaga gccgactgac tcgacaatac caataccttc atgacctaaa atggtaccat
     2761 gagtagtctc tgggacatct ccacctaaaa tatgtaagtc tgttccacag attgttgttt
     2821 tcaataaacg aaccacagca tctgtcggag caagaatctc tggttttggt tgatcaataa
     2881 gctccagctg acctggagca acatatgtag ctgctttcat aaaacgtctc caaatttagt
     2941 ctagaaaatg taatcgatta catttttagt ataatttttt acaccctctt tgtcaattaa
     3001 taaagggtaa ttttagaaaa agtctgacaa taccattatt ttggtttttg tttgatatat
     3061 aaaggttttt aacgctatta acatcattaa aaaagcaatc actccttgtt ttattagaaa
     3121 ataaagctca tcagatagac gcaacatgtt attttcttca gctaattgct aagtgcagct
     3181 aagtcgtaac tatcagccac tttatgaata tggcaaatga agcttccccc tctgatggaa
     3241 tgctctgtaa aaccattgtc ttaaaagctt tatatgatat ctgagaaact acccctgagt
     3301 taagctatct caacacaagg cactgccgac tttttcatct aacacagccc ttttcatagc
     3361 tagataaaaa aatagaagcc aagcagctcc tatttttact attaatgatt gatattattt
     3421 ccgacgtcct ggacgctctg cgtaaccata ataagcatca ttcatgattt cttccatgtg
     3481 ctcaaccatt ggcaagcgtg ggttagcagg tgagcattga tcctcgtagg caagataagc
     3541 aagctcacga gtgtgtgcct tccattcttc ctcatcaatt ccttgatctc tgaaattcat
     3601 cttaatgcct aagcgacagc caagatcata aacagcttta gcataagatt caacaccttc
     3661 ttctggagta gatgccggaa gtcctagcaa cttagcaatg tcttgatatt tttcatcggc
     3721 gcgatagtaa ttgtacttag gccatgttgc tgttttagca ggacgggtac cattgtaacg
     3781 aataacgtat ggaagcaaga tagcattggt acgtccatga acagtatgga attgtgcacc
     3841 aatcttatga gccattgagt gagaaatacc caggaaggca ttagcaaagg ccatacctgc
     3901 cattgttgag gcattatgca ttttttcacg tgactcaaag tcagcttcct taacagattt
     3961 ttcaaggttt tcaaagacaa tcttaatggc ttgaagggcc aaaccatctg taaagtcatt
     4021 agccatttgt gatacgtaag cctcggttgc gtgggtcaac acgtccatac ctgtatcagc
     4081 tgcaatgaag cctggtactg taagcaccaa cgccgggtca acaatggcta ccgttggtgt
     4141 caatgaatag tcagcaattg ggtacttgcg gttgttggcc ttatctgaga taacagcaaa
     4201 cggtgtaacc tctgatcctg tacctgaggt tgttggaata gccacaaatt ttgttttctt
     4261 accaagctca gggaacttga aggcacgttt acgaatatcc atgaattttt gaacaagatc
     4321 atggaagtca acctctggtt gctcatagaa taaccacatt acctttgcag cgtccattgg
     4381 agaaccaccg ccaagagcga taatcgtatc tggcttaaag gtacgcatca gctcagtacc
     4441 tttcataacc gttgtgatat caggatctgg ctcaacatct gcaaaaattt gataaacaac
     4501 cttattacga cgaaggtcaa gctgctcgat gatacgatct aagaagccaa gctcaaccat
     4561 agcgtggtcg gtaacaatca tcacacgctc aacgtcacga catttttgaa ggtattgaat
     4621 tgaatcacgc tcgaagtatg tttttgaagg aactttaaac cattgcatat tatttctacg
     4681 tcttcctact tttttgatgt tcaagagatt tacagcacta acattatcac caactgagtt
     4741 acgtccataa gaaccacagc ccaatgttaa tgacggtagg aaggcattat aaacatcacc
     4801 gataccacca aatgtagaag gtgaattcca aatcacacga atagcacgaa tttttgttcc
     4861 aaattcctta gctaagtctg catcagcagt atgaatagcg gctgagtgac caagtccgtt
     4921 aaattcaacc atttgacgag ccttttcaac accatctgtg cgagattcag ccttcaaaac
     4981 agcgataact ggtgacaatt tttcacgtgt taatggctca ttttcagaaa cttccttaca
     5041 ttctgctgca aggatattcg ttccttctgg tactgtaaag cctgcctgct cagcaatcca
     5101 agctgctggc ttaccaacaa tattagggtt cagcttagca cctgcacagt ttttactgtt
     5161 agccttagca ccaaagcaga attcctctaa cagagccttt tcctttttgt tgacaaagta
     5221 agtgtggtaa gacttaaatt cactaacaaa ctcgtcataa atctccttgt cgataataac
     5281 agcctgctca gaagcacaaa ccataccatt gtcaaatgat ttagacatga caatatcgtg
     5341 tgctgcctga cgaatgttag cggatttttc aacataggca ggcacgttac cagcaccaac
     5401 cccaagagct ggcttaccac atgagtaggc tgccttaacc atagcattac caccagttgc
     5461 aaggattgtt gcaataccat catgattcat cagagcgtta gttgcttcta gtgatggggt
     5521 ttcaatccat tgaacacagt cctcaggagc tcctgctgca atggctgcat cacgaacaat
     5581 gcgtgctgca tgagctgatg attcttgagc tgatgggtgg aaggcaaaaa taatagggtt
     5641 acgtgttttt aaggagatta aagatttaaa aatagctgtt gacgttgggt tagttgttgg
     5701 ggtaatccca caaataacac ctactggctc agcaattaag gtcaaacctg ttacatcgtc
     5761 ttcttcaatg atacctactg ttttttggtg acgcatgtta ttaacaacgt gctcacatgc
     5821 gaaaaggttt ttggtagcct tatcttcaaa aactccgcga ccagtttctt cataggcatg
     5881 cttagctaac tcaccatgtg cgtccaaagc agcaacagag gccttcgcta caatgtagtc
     5941 aacctgttct tgagttaact gacgcatttt atcaagcgct actaaacctt tttgaacaag
     6001 agcgtcaatt gttgcggcaa cagatgttgt ttcaacagta ctattttttt cagtcatttg
     6061 agactccttt accttgttaa aagtttcaca attttgttta caaaaatatt atatcatttt
     6121 ttggcatttt gtaaatcatt tcacaataaa attgtgatgt tttttcaatc aatttccgaa
     6181 actctttgat aacaaggggt ttggcttggt ggattttttc tgaaataatg gctgacgcat
     6241 tcactttgtt ccgaaagcgc tttctttttt tagatcaggc taaattattt aatgatccgt
     6301 ttttaaaagc acgtcaccgt cagcaataac agccaataat gacactgtct aacaggtgga
     6361 gctttatctc gcgctaaagg gcgcaagacg atctaaaaat cacatcatga aaaggcttga
     6421 tctgtttgta agaccaagcc ttcgttatta attcttaaca aattgttgtt agcaccacta
     6481 tttagcatct ttttttgctg ctcgctcaac agccgcctga atcgttgaga catataagtc
     6541 agcacctttt aatttggcgt cgttattgta gtggacccca tcactaccat accagatatt
     6601 gggattttcg actgccgcct tgtaccagtc agcaactgtt acatagctat attttttagc
     6661 tagctgcaac aaatgctctc tagcctctgc tacctgtgct gcattcttag catcataggg
     6721 cgacacaatc accaagcgat gcccctttgg tagtgcataa ataaagcctt gaatatcctg
     6781 cgcataatta taaagagaat taacaccaac agctaaaacc gttgtttttg ataagctctt
     6841 ggattggata tgattttcaa aaagctcaaa ggcttcactg aaattgcggc tgacagcagc
     6901 gtctagttga gcagtcggca ttaattttga aaaagcgtca ctagacctca aggcaactga
     6961 gtcaccaata atgctaacat cactaagagc atgcgcatct cctgctgcca aagtatgtgt
     7021 cttattgaga ttactttgag attgctgcaa ggaatctact aaaagctggg tctcaaaatt
     7081 accgaccctt ggtgctgtca aacaggtacc aaccatcaac aaaaagagtc ctaaagcaag
     7141 ccctgataac catttcttat agggattaca atcaattgct aaaccaaaaa gctgtggtgt
     7201 cttgccttga atcaaaggct caataatgta ataagaaagc gttgaaaaca ctactgaaaa
     7261 gaaaaccgtt aagatcactg ccagccagtt agacatcagc tgtgtaaaaa taatgtaaaa
     7321 tggccaatgg aataaataaa tcccatagct aatatccgca agataggtca caagcagtgg
     7381 ttcctgccag gttggtgttt gatcgctcaa aacacgcgca gcataaatca ttaccgaagc
     7441 aaaaagactg gctaagacaa aaccgaaaag ataggtaaag atatggttaa aatctaacac
     7501 aagcgttaga aacaacaaca gagcaaaagc gccagccatc actccaataa catgtagcct
     7561 tggccacagc ttaacattct tttgaaagcg aacagtcgtg tccttaattc ccgtcatggt
     7621 tgcaaacatc gctcctaaaa agaaaggaaa gctgtgtgaa agcgttgaaa agtaaacaga
     7681 agaaaaatct gatacaaaga aggctctgat aaacatgctg aagtagctaa gcgtgaacac
     7741 tgcggaagaa attaaaaaca gaatgcctct aaatttcttc tgactgtagc cttttttagc
     7801 taataaccaa accaacagcc cccaaagcaa ataaaaatgc acctcaatgg ccaagctcca
     7861 ggtatgcaca aacagatgcg gaatgaattg actttcatag ctactgcctg tcagtagctc
     7921 ataactattt gttgtaaacc ctagggcagc tgctatttgc tgaccgatac cagcaatgaa
     7981 gtcacttttg actaaaaaag taaagggaat tgtcaagaga attaacaaga caagcggcgg
     8041 tacaatacga taaaaacgcc ttctaaaaaa agcaaccaca tcaatggttt gttttgagac
     8101 atattcatca atcaacaagg ctgtaatcaa atagcctgaa aaagtaaaga agatgtcaac
     8161 gccaacaaag cctcctgaaa aagtatgctt aaaaaagtga tagagcaaca ccagcaaaag
     8221 acctgttacc ctaataaacg aaaaccattt tatcctcatt tttgaaatat cccctgctta
     8281 aaggttcctt tgtaaacctt tgaatccttc gccttcaaag tacccttgcc atcagcctga
     8341 ccttttttaa attgtccgct gtaagaccac cctgtactag ctgtaaacgt tccttctcca
     8401 tcaaagacac ctttattaaa atccccaaca taggtatcgc cattagggta aaccaatttc
     8461 cctttaccat tcattctatg attaaggaca tagccggtgt acttgatttg cccattgtca
     8521 taggtcaagc ttgcttttga ggatatggtc aaggtaaaaa ccgacaatcc acagacaata
     8581 atcacaagga ctgaaataat ctctagcttt gtccgagtga tctgccattt ttgaatgtta
     8641 tttattattg ctttcattac tattactcat ctatttccac atgtgattca tgttcagcgc
     8701 tgatttgact caaccaatgc tgacagcccg ctttaaccaa gcggtaggtt tcttcaaaat
     8761 ctcctgtata ccaaggatcc ggaacgcctc cttcaataaa aagatggatc ttggaatccc
     8821 actgatgctt ggacatttgc ttcaaatctc tgatattatg gctatccatt ccgataatat
     8881 agtcaaaggc ttcaaagtca aagctggtga tttgctgaga ggttttcttg gtatcatagc
     8941 taatctgata ttgctgtaat agcgattgtg tcccatgatg aattggattg ccatgctccc
     9001 agccagaggt tgcacgactc tccacctgta gctcatcagg actggccata cttttcatga
     9061 caaattcggc cataggacta cgacaaatat ttccaagaca aacaaagcat acttttttca
     9121 tgaaaaactc cttttaccta ttatagcaaa attatagggc caaaaggaga aatcgctctt
     9181 ataattttcg ttcaattgat ctaaaaatgt tttttaatgc tttgtctagt gaaagcacct
     9241 ctgcttccct gaccaatcac ccctcacctc acatcgtttt acttttttac tcagtaagct
     9301 attgacaata caaaagactt gacaccggta aaaacaaagg aatcaagtct tacatagcta
     9361 tttatgtctt aatggttttt tcatagggat agcctaagtg ctgataggct ttttcggtga
     9421 caactcggcc tgttctggta cgcatgataa aacccttttg aattaaataa ggctcgtaca
     9481 tgtcttctac tgtatctcgc tcctctgcta tattgacaga tagagtccca agaccaaccg
     9541 gccctccttg gtacacctca atcatggtac gaagaatctt ttggtccaca taatctaaac
     9601 cttcttgatc cacatctaac atcgttagag ccttatctgt gatttgagtc gtaatcattc
     9661 catcacccat aatttgagca taatcacgca ccctttttaa cagccgatta gcaatacgag
     9721 gggttccacg actcctgcgt gccagttcat aagcggcctc atgcttgatt gtcatgtcaa
     9781 aaatatcagc tgtacgctcc acaatctctg ttaaatcagc tgtctgataa tattccatat
     9841 gcccagtaat cccaaaacga gccctcaaag gatttgacag catgcctgca cgagtcgttg
     9901 ctccaattaa tgtaaaggga ggcagctcca aatgcacact ccggctagtg tctccagcgc
     9961 caatcatgat atcaatgtaa aaatcctcca tggcactgta caagatttcc tcaacagcca
    10021 tcggcatacg atgaatttca tcaataaaga ggacatctcc tggctctaaa tcattcaaaa
    10081 ttgccaccaa atcaccagct ttttcaatgg ctgggccaga ggtctgcttg agatgaactc
    10141 ccaattcatt ggcaatgaca aaggccatcg ttgttttacc caagcctggg gaaccaaata
    10201 acaggacatg atccaaggat tcctcacgcc tcttggctgc ctcaataaaa atcatcagct
    10261 ggtctttaac cctatcctga ccaatatact cacgtaaata ctgtggacgt agtgtcctct
    10321 caacagatcc ttcatcgcct atcagatcat tatctaaaat tcttgtcata gagctattat
    10381 agcataaata gatgatttag ctttaaccaa cacgccacca gtcaatatca ctaagtaatt
    10441 gggcagaatg aagtagaaat aaagcagcta aaaacagata gtattggtat tttttaaaca
    10501 tataaatgga actccttta
//
LOCUS       DARYXS010000072        10391 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.073, whole genome shotgun sequence.
ACCESSION   DARYXS010000072 DARYXS010000000
VERSION     DARYXS010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10391
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.073"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            41..907
                     /locus_tag="TV193_001478"
     CDS             41..907
                     /locus_tag="TV193_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEL1513660.1"
                     /translation="MKSKKKFFLLSLLALSAFFLSACSSWIDKGESITAVGSTALQPL
                     VEAAADEFGSNNLGKSVNVQGGGSGTGLSQVQSGAVQVGNSDVFAEEKDGIDAAKLVD
                     HQVAVAGLAVIANPKVKVSNLTSKQLQKIFSGEYTNWKQVGGQDLAISVINRAASSGS
                     RATFDSVIMKGVTAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLRLNGFK
                     ANAKNVATNDWPIWSYEHMYTKGKPDGLTKEFLDYVLSDEVQKTIVTHMGYIAITDMK
                     VVKSYDGKVTDK"
     gene            918..1853
                     /gene="pstC"
                     /locus_tag="TV193_001479"
     CDS             918..1853
                     /gene="pstC"
                     /locus_tag="TV193_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1513661.1"
                     /translation="MKNQELAKQLASPSKNSRLEAFGRTITFFCLALIVFIVAMILLF
                     VAQKGLSTFFVNKVNLFDFLFGTEWQPSVKNAAGVPYLGALPMIAGSFLVTILSALVA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVVVPFIRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPASLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            1843..2730
                     /gene="pstA"
                     /locus_tag="TV193_001480"
     CDS             1843..2730
                     /gene="pstA"
                     /locus_tag="TV193_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1513662.1"
                     /translation="MNAKKVDKVATGSLYTIAGIIVAILASLILFILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLVVTLIISIPLSTGAGIYLAEYAKKGPVTNVIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFHVVIPEALPSIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NLSARFIGKRIHAKMTAAK"
     gene            2747..3550
                     /gene="pstB"
                     /locus_tag="TV193_001481"
     CDS             2747..3550
                     /gene="pstB"
                     /locus_tag="TV193_001481"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1513663.1"
                     /translation="MTEYNWNERHIITFPEETIALATKDLHVYYGSKEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVRDKRVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTRNIFQNATCQSTNDYVSGHFG"
     gene            3564..4322
                     /gene="pstB"
                     /locus_tag="TV193_001482"
     CDS             3564..4322
                     /gene="pstB"
                     /locus_tag="TV193_001482"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1513664.1"
                     /translation="MAEPILQIRDLSVYYNKKKTLKDVSLDFYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKAVLDHAVESSLKGASIWSEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLFSLKKDYTMVIVTRSMQQASRLSDRTG
                     FFLEGDLLEFGPTKAMFMNPKRKETEDYISGKFG"
     gene            4393..5046
                     /gene="phoU"
                     /locus_tag="TV193_001483"
     CDS             4393..5046
                     /gene="phoU"
                     /locus_tag="TV193_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL1513665.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLSQINKTVRAFVSHDRELAK
                     EVIEEDDTINGFETKLEKKSLEIIALQQPVSNDLRTVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPIVEEHINLMGKAVKQMVEEALNAYINADDAKAYEIAASDEIIDNY
                     FREIQSLAVEEIRKTPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            5280..7817
                     /locus_tag="TV193_001484"
     CDS             5280..7817
                     /locus_tag="TV193_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEL1513666.1"
                     /translation="MKKVEHLIEKFIPENYNIFLDINRSTKTFTGNVAINGEALDNQV
                     SFHQKDLAINAILLDNEAVSYHVDDDNELVRVELPETGMMTLVIEFSGNITDNMTGIY
                     PSYYTKDGEKQEVISTQFESHFAREAFPCIDEPEAKATFDLSLTFDQAEGEIALSNMP
                     EVNAERRKETGLWTFETTPRMSSYLLAFALGDLHGKTTKSKNGTTVGVYATKAHPLTS
                     LDFSLDIAVRVIDFYEDYFGVRYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDG
                     NSTARSRQNVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVAINAIEPSWR
                     IFEDFQTTGVPLALKRDATDGVQSVHVAVNHPDEINTLFDPAIVYAKGSRLMHMLRRW
                     IGDKDFAAGLRLYFEKHQYRNTVGRDLWQALSEASGKDVAAFMDAWLEQPGYPVLTAR
                     VDNDQLILSQKQFFIGEASDQKRLWPIPLNANWKGLPDVLTEESIVISGFSQLAAQNK
                     GTLRFNTENTAHYITDYQGQLFHSLVDDLKHLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDKKSYMVAAAVQQVIRGLEQFIDEGTSAEQSFNRLISSIFQEDFRQLGFE
                     KRANESDEDEMVRQIALHHLLVGGNRDVIKQAKTIFEAYANRIEAIPAAIRRSVLVSQ
                     IKYFEIADLVDAYFDAYVATKDNNLRADLSAALATTANPSTLKRIQYSLKDKDIIKPQ
                     DLAAWYSFLLDQASAQESIWRWARENWKWIKASLGGDMSFDKFIIYPANHFKTAERLA
                     EYKAFFEPQLDDMAISRNISMGINEISARVALIDSEKEAIANALSQY"
     gene            8236..8910
                     /locus_tag="TV193_001485"
     CDS             8236..8910
                     /locus_tag="TV193_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1513667.1"
                     /translation="MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTAKESIDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKEFDLLIY
                     ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGY
                     ILKANE"
     gene            8903..10213
                     /locus_tag="TV193_001486"
     CDS             8903..10213
                     /locus_tag="TV193_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1513668.1"
                     /translation="MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYS
                     TVDSSLISVGQNASNYANRTMARISSFYFDAENNLIQALPELEASKSLGSSTTNMDII
                     LFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
                     PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILDNSEHIASSLDEVRNMRILTTNL
                     LNLARSDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISVNQINRPLKTDKALLK
                     QLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVD
                     KARARQKGGFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL"
BASE COUNT         2999 a         1936 c         2302 g         3154 t
ORIGIN      
        1 ttcgctataa acctttattt ttatgaatag gaatagaata atgaaatcga aaaagaaatt
       61 ctttttgtta agtcttttag ccttgtcggc tttctttttg tcagcctgct caagctggat
      121 tgataaggga gaatccataa cagcggtagg ctcaacagca ttacagccct tagtagaagc
      181 cgcagctgat gagtttggaa gcaataacct cggaaaatct gttaatgttc aaggaggcgg
      241 ctctggcact ggcttatcac aggtgcagtc aggtgctgtt caggtaggca atagtgatgt
      301 ctttgcagaa gaaaaggacg ggattgatgc tgctaagctt gttgatcacc aggttgccgt
      361 agcaggactt gctgtcattg ccaatcctaa ggtcaaggta tctaatctca caagcaagca
      421 gctacaaaag attttctcag gtgaatatac caactggaag caggttggtg gacaggatct
      481 tgctatttca gtgattaatc gagcggcaag ctcaggctca cgtgctacct ttgatagtgt
      541 catcatgaag ggtgttactg ctaagcaaag tcaagagcag gattctaacg gtatggttaa
      601 atcaattgtg tctcagacac cgggggccat ttcttactta tcctttgcct atgtggattc
      661 gtctgtaaaa tcattacgat tgaatggctt taaggccaat gccaaaaatg tagcaaccaa
      721 tgattggccc atctggtcct atgagcatat gtataccaaa ggcaagccag acggcttaac
      781 caaggaattt ttggattatg tgctatcaga tgaggtccaa aaaaccattg tgacacatat
      841 gggttatatt gctatcactg atatgaaggt cgtcaaatcc tatgatggaa aagttacaga
      901 taaataatgg gggaattatg aaaaatcagg aattagctaa gcaattagcc tcaccatcaa
      961 aaaattcacg acttgaagca tttggtcgta cgattacctt tttttgcctc gccttaattg
     1021 tttttatcgt tgcaatgatt ttactttttg tggctcaaaa gggcttgtct accttttttg
     1081 taaacaaggt taatcttttt gatttcctat ttggtacaga gtggcagcct agcgttaaaa
     1141 atgctgccgg tgttccttat cttggagctc ttccgatgat tgctggatcg tttttagtca
     1201 cgattttatc agccttggtg gcaacaccat ttgccattgg ggcagcagta tttatgactg
     1261 aaatttcacc caagtacggg gcaaaactat tacagccagc agttgaattg cttgtaggta
     1321 tcccgtcagt tgtttatggc tttattggct tgcaggttgt tgttcctttt attcgttcta
     1381 tttttggtgg aacaggcttt ggtatcctat caggggtctg tgtcttgttt gtcatgattt
     1441 taccgacggt tacctttatg acaacagata gtctgcgcgc tgttcctcgt cattatcgtg
     1501 aggcttctat ggctatgggg gctacacgtt ggcaaaccat ttggcgagtg gttttaaatg
     1561 cggctcgtcc tggtattttt actgctgtta tttttggtat ggctagagcc tttggtgagg
     1621 ccttagccat tcaaatggtt gtgggaaatt cagcagtcat gccggcttca ctaaccactc
     1681 cagcggctac attgacctct gtattgacta tgggaattgg taatacagtt atgggaactg
     1741 ttcaaaataa tgtgctatgg tcattagccc ttgtcttatt gctgatgagt ctagctttta
     1801 attcccttgt caaattaatt acgaaagaga gaaagagaaa ttatgaacgc taaaaaggtt
     1861 gataaagtag caactggtag cttgtatact attgctggaa ttattgtagc tattttagct
     1921 tccctaattc tgtttattct tgtgcgtggc ctacctcaca tcagctggtc gtttttaaca
     1981 gggaaatcat cgtcctatga agctggtgga ggtattggga ttcagcttta taattcattt
     2041 ttcttgctgg tagtaacctt gattatttcc attcccctat caacaggtgc tggcatttat
     2101 ttggccgaat acgctaaaaa aggacctgtg acaaatgtga ttagaacctg tattgaaatc
     2161 ctatcctcat tgccatctgt tgtggttgga ttgtttggct accttatttt tgttgtacag
     2221 tttgaatatg gcttttctat tatatcaggt gcccttgctt tgacggtatt taatcttccg
     2281 caaatgacaa gaaacgttga ggatagcttg ctgcatgtgc atcatactca aagagaggca
     2341 gggctagccc ttgggctttc acgctgggaa acggtttttc atgtggttat tccagaggcc
     2401 ttgccaagta ttgtgacagg tattgttttg gcttcaggtc gtatctttgg tgaagcagct
     2461 gctcttatct atactgcggg tcagtctgcc ccagcgcttg attggtcaaa ttggaaccct
     2521 ttgagcgtga caagccctat ttcaattttc cgtcaatctg aaaccctagc tgttcatatt
     2581 tggaaggtca atagtgaagg gacaatccct gatgcaacac ttgtttctgc tggtagtgca
     2641 gcggtgttgt tgatttttat ccttattttc aatctatcag ctcgctttat tggcaagcgt
     2701 attcatgcta agatgacagc agcaaaataa gacattggag agattcatga cagaatataa
     2761 ttggaacgaa cgtcatatca ttacatttcc agaagaaacg attgccctag ctactaagga
     2821 tctgcatgtt tattatggta gcaaggaggc aatcaagggg attgatatgc aattcgaaaa
     2881 aaataaaatt acagccctaa ttggaccctc aggctgtggc aagtcaacct atctgcgcag
     2941 cctcaatcgc atgaatgaca ccattgatat tgctagagta acaggtgaaa ttttgtatca
     3001 aggcattgat gtcaatcgaa aggacatgaa tgtgtatgaa atccgtaagc acctaggaat
     3061 ggtctttcaa aggccaaatc catttgccaa gtctatttat aaaaacatca cctttgctca
     3121 tgaaagagca ggagtgagag ataaaagggt tttagatgag attgtcgaaa cctccctcaa
     3181 gcaggctgca ctatgggatc aggtcaagga cgatcttcat aaatcagcct ttaccctttc
     3241 aggaggtcag cagcagcgct tgtgtattgc tagggctatt tcggttaagc cggatatctt
     3301 gttgatggac gaaccagctt cagcccttga tcctattgca accatgcagc tagaagaaac
     3361 catgtttgag ttgaagaagg attacaccat tattatcgtt actcataaca tgcagcaggc
     3421 cgctagagca agtgattaca ctgctttctt ctatttgggt gacttaattg aatacgataa
     3481 aacgcgtaac attttccaaa acgctacctg tcagtccaca aatgattacg tctcagggca
     3541 ctttggttag aaagaaggat atgatggcag aacctatttt acaaatcaga gatctttctg
     3601 tttactataa taaaaagaaa accttaaagg acgtgtcctt agatttttac ccaaatgaaa
     3661 tcacagcact cattggccct tcagggtctg ggaaatcaac acttttgcgt tccatcaatc
     3721 gcatgaatga cctgaatcca gaggtaacca ttacggggtc aatcgtttat aatggacata
     3781 acatttacag tccaagaaca gacactgttg atttgcgaaa agaaattggt atggtctttc
     3841 agcagcccaa tccctttcca atgtctatct atgaaaacgt tgtctatggc ttgcgcctaa
     3901 agggcattag agataaggct gttttagatc acgctgttga atcctctctc aaaggagcct
     3961 ccatctggag tgaggtcaag gataggcttc atgattcagc tgttggacta tcaggaggtc
     4021 aacagcagcg tgtctgcata gcaagggttc tggcaaccag ccctaaaatc attttgttag
     4081 atgagccaac atcggcttta gatcccattt cagccggcaa aatcgaagag accctgttct
     4141 cactaaaaaa ggattatacg atggttatcg ttacccgctc catgcagcag gcctcgcgct
     4201 tgtcagaccg gacaggcttc ttcttagagg gagaccttct tgagtttggt cctactaagg
     4261 caatgtttat gaaccctaag aggaaggaaa cagaagatta tatttcgggt aaatttggct
     4321 aagggatctt gtttgtagtc taggtatccg ctctgtttag gataataaat gaatcaatag
     4381 aaagaaaaaa tgatgttaag aactaaattt gaagaagaat tagacaagct acacaatcag
     4441 ttttactcta tgggaacaga agtcttgtct caaatcaata aaaccgttcg tgcctttgtc
     4501 agtcatgacc gcgaattggc caaagaggtg attgaggaag acgataccat caatggattt
     4561 gaaacaaaat tagaaaaaaa gtctcttgaa attatcgcct tacagcagcc tgtttcaaac
     4621 gatttgcgaa cagttattac tgttttgaag gcctcaagtg atattgagcg tatgggagat
     4681 cacgctgcct ctatcgctaa agcaaccatt cgcatgaaag gagaagagcg tatcccgatt
     4741 gttgaggagc atatcaactt gatggggaag gcagtcaagc agatggttga agaggcgcta
     4801 aatgcttata ttaatgcaga tgatgccaag gcctatgaaa ttgctgcttc agacgaaatc
     4861 attgataatt atttccgcga aatccaatct ctagctgtcg aagaaattcg caagacacca
     4921 gatgccgtct ttgctggcaa ggaatacttc caggttctca tgtatttaga gcgtatcggt
     4981 gactatgctc gtaatatttg tgaatggatt gtctatttaa aaactggaaa aattattgaa
     5041 ttataagaaa gtatggtata atgggggctg ggtgaacttc tcagttcctc gttttattat
     5101 agcgattaaa aggttttaga ggctggagct tcagctgagc tgactatcag ctgtcaagct
     5161 tctagacaaa atgaaagata acaataagct agtcgtctaa gggactagac ggcaggattg
     5221 attatattaa gaatgtgacc ttgtcccatc actaatttaa tgacatatta aggagttgta
     5281 tgaaaaaagt agaacatctt attgaaaagt ttattcctga aaattataat attttcttag
     5341 acattaatcg cagcacaaaa accttcacag gtaatgttgc aatcaatggt gaagcattag
     5401 ataatcaagt gtcatttcac caaaaggact tggcaatcaa tgccatttta cttgacaatg
     5461 aagctgttag ctatcatgtt gacgatgaca atgagcttgt gcgtgttgag ctgccagaga
     5521 ctggtatgat gacgcttgtc attgaatttt caggtaatat tactgacaat atgactggta
     5581 tttacccgtc ctattacaca aaagatggtg aaaaacagga ggttatttca acgcagtttg
     5641 aaagccattt tgcgcgtgag gcctttccat gtattgacga gcctgaagca aaggctacct
     5701 ttgacttaag cttgacattt gaccaagcag agggcgagat tgctctatca aatatgcctg
     5761 aggtcaatgc tgagcgccgc aaggagaccg gtctttggac ctttgagaca actcctagaa
     5821 tgtcttctta tctgctggcc tttgccttag gagacttgca tggcaaaaca acaaaaagta
     5881 aaaacgggac aacagttggt gtttatgcaa ccaaggctca cccactgacc tcgctagatt
     5941 tttcattgga tattgctgta cgtgtcattg atttttacga agactacttt ggggttcgct
     6001 atcctattcc gcaatctcta aatattgctc ttcctgattt ttcatctgga gcgatggaaa
     6061 actggggctt gattacctat cgtgaaattt acctgttggt tgatggcaat tcaacagccc
     6121 gcagcagaca aaatgttgct cttgttgtgg cacacgagat tgcccatcaa tggtttggta
     6181 atcttgtaac catgaaatgg tgggacgatc tttggctaaa tgaaagcttt gccaatatga
     6241 tggaatatgt agccatcaat gctattgagc cgtcatggcg tatttttgag gatttccaaa
     6301 caacaggtgt gccgctggct cttaagcgtg atgcaacaga cggtgttcaa tcagtccatg
     6361 ttgctgttaa tcacccagat gagattaata ccctgtttga tccagctatt gtctatgcca
     6421 aaggtagccg cttaatgcat atgcttcgtc gctggattgg cgataaggat tttgcggcag
     6481 gtctgcgcct ttactttgaa aagcatcaat accgtaatac tgtaggacgt gatttgtggc
     6541 aggctctttc agaagcttct ggtaaagatg ttgctgcgtt tatggacgct tggctagagc
     6601 agccaggcta tcctgtctta acggccagag ttgacaatga tcagttgatt ctcagccaaa
     6661 agcagttctt tattggtgag gcaagcgacc aaaagagact atggccaatt ccactaaatg
     6721 cgaactggaa aggtcttcct gacgtactga cagaggagtc catcgttatt tcaggcttta
     6781 gtcaattagc cgcccaaaat aaaggaacac ttcgctttaa tacagaaaat acagcgcatt
     6841 acattacaga ttatcaggga cagctctttc atagcttagt tgatgatttg aagcatcttg
     6901 acaacacctc tgcccttcaa gtgattcaag agcgccgctt gctggctgat agcggtctga
     6961 tttcttatgc agagctggtt gacttaatcg ctcagctaga tgacaaaaaa tcctatatgg
     7021 ttgctgcagc tgttcagcag gttattagag gcttagagca gttcattgat gaaggaacct
     7081 cagcagagca gtccttcaat cgattgattt cttctatttt ccaagaggac ttcaggcagc
     7141 ttggatttga aaagagggca aatgaatctg atgaagatga aatggttcgt caaattgctt
     7201 tacatcacct gttggttgga ggcaatcgtg atgtgatcaa gcaggccaag actatctttg
     7261 aagcttatgc aaatcgtatc gaagccattc cagcagccat tcgccgctcg gtattggtga
     7321 gtcagatcaa gtattttgaa atagctgact tggttgatgc ttattttgat gcttatgttg
     7381 caaccaagga caacaatctt cgagctgatt tgagcgccgc cttagcaaca acagctaatc
     7441 catcaactct taagcgcatt cagtacagct taaaggataa ggatattatt aagccacagg
     7501 acttagcagc ttggtacagc tttttgcttg atcaggcctc tgcacaagaa agcatttggc
     7561 gttgggctag agaaaattgg aagtggatta aggcttcact gggtggtgat atgagctttg
     7621 acaagtttat tatttaccct gctaaccatt ttaaaacagc agagcgttta gctgaatata
     7681 aggccttctt tgagccacag cttgatgata tggcgattag tcgcaatatt tcgatgggga
     7741 taaatgaaat ttcagctcga gttgccctca ttgatagtga aaaggaagct atcgctaatg
     7801 ctttaagtca gtactaatga tatcacaaag gagctgggga ccatcctcaa ctcctttatt
     7861 ggtgtcaaag ctactatctt taagtaacat ttagatcaaa gggtaattgc tgtagcttag
     7921 tggcactgcc tgtcagcttt tggcaaatga ggaggcttca atcataagca gtggttaatc
     7981 ttagcgccgt aaattactag ttgatcagag tcagagctta ggacggatag gtcatagaga
     8041 caattctttg tctgtcagtt ttataactta agtaggtctc cagactaact gtatgcttat
     8101 gacctgtcat gagcaatagt ttagcaaagc ttaagctttt tgtgttatcg ttagattaga
     8161 gaattcattt agtaaggtaa tccctaaaga ctacttgagc gaggctgtta gtctttagag
     8221 aattgaggta tcataatgat aaaactatta ttagtagaag acgatttaag cttgtcaaat
     8281 tctatctttg attttttaga tgactttgct gatgtgacgc aggtttttga tggtgacgaa
     8341 ggactctatg aggcagaaag cggtatttat gatttgattc tgttagattt gatgctgcct
     8401 gaaaaggatg gctttcaagt gttaaaagcc ttacgtgaaa aagacatcaa aattcccgtc
     8461 ttgatcatga ctgccaaaga aagcatcgat gacaaagggc atggctttga gcttggtgct
     8521 gatgactatt taaccaagcc cttttaccta gaagaattaa aaatgcggat tcaggccttg
     8581 cttaagcgcg taggaaagtt taatgacaag agccttaaat ttggcaacct gactgtagat
     8641 actacccgta aagaggtaca ggtcaatggg caggccatag agctattagg caaggagttt
     8701 gatttactaa tctatatcct tcaaaatcaa aatgttattt tgccaaaatc acaaattttt
     8761 gatcgtatct ggggctttga tagtgatacc actatctctg ttgtagaggt ctatgtctct
     8821 aaaattcgta agaagcttaa ggggacagac tttgttaatc atcttcaaac cttgagaagt
     8881 gtaggatata tcttaaaagc taatgaataa actaaaaaaa ggattattgt ccgataatta
     8941 tacgcatttt tttcatttct ttgctatttt tacaggcatt tttgttgtca tgaccatcat
     9001 tattttacaa atcatgaggt ttagtgtcta ttccacagta gacagcagtc tcatttcggt
     9061 cggtcaaaat gccagcaact atgctaatag gaccatggcg agaatatctt ccttttattt
     9121 tgatgcagaa aataacctta ttcaggctct tcctgaactg gaagcgtcaa aatcacttgg
     9181 ctcctccacc actaatatgg atattatttt atttagtgct aatgggacga tattgaactc
     9241 ctttgacgct ttctctaatt accaaagctt tcgtttagac aaaagccagc tcaataacat
     9301 tgtcaccaca cagctgatga atttttatgg gcaaaaggag aaataccata ccctaaccgt
     9361 taaggttcac attaaaaact atccagcagt ggcttatatg atggcagtgg ttaatgttca
     9421 gcagctggat actgctaatg agcgctatga acagattatt atcatggtta tgattgtctt
     9481 ttggttaatt tcgattttgg ccagtattta tttggctaag tggagcagaa agccaattat
     9541 ggagagctat gccaagcaaa aaatgtttgt agaaaatgcc agtcatgagc ttaggactcc
     9601 tttagcggtg ctgcaaaatc gtttggaatc gctgtttaga aagcctaacg aaaccatttt
     9661 agacaatagc gagcatattg cgtcaagcct agatgaggtt cgtaatatga gaatattaac
     9721 aactaatctg ttaaatttag ccagaagtga tgatgggatc aagccgcagc tagttgatgt
     9781 tgatgcagcc ttttttgata ctgtttttga aaattatcaa ttagttgcag aagagtcagg
     9841 caagcagttt atctcagtta atcagatcaa taggccctta aagacggata aggctttgct
     9901 caagcagctg atgaccattt tgtttgataa tgcgatcaaa tacactgatc ataacggtgt
     9961 ggttgaggtc aaggttagaa cgaccgataa gcatttattg atttctgtta ttgataatgg
    10021 cccagggatc aaggatgatg ataagaaaaa gatttttgat cgcttttacc gagtggataa
    10081 ggcaagggca cgccaaaaag gagggtttgg actcggattg gccttagcgc agcagatcgt
    10141 tacctcatta aaaggaacga ttaccgtcag tgataataag cctaccggcg ccatctttga
    10201 agtaaaatta tagcactgag ttcttgctag cccataatca gtatgaaaat aacagtcact
    10261 agatcaagaa gtctagtgac tttttttatt gtcttctttt tgctgttgac caagcagttg
    10321 acaagaaaat tccaatagat agtttaaagc caataaaacc attattaggc ttgcattaca
    10381 ggcaggtatc a
//
LOCUS       DARYXS010000073        10196 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.074, whole genome shotgun sequence.
ACCESSION   DARYXS010000073 DARYXS010000000
VERSION     DARYXS010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10196
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.074"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            19..870
                     /locus_tag="TV193_001487"
     CDS             19..870
                     /locus_tag="TV193_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEL1513669.1"
                     /translation="MSNLSSIDTKFLLSLIDDPLMLVVHLLDILIVAYLIYRFIKSLA
                     GTKIMSLVQGVIFFIIIRVIAEWIGFTTITYLMNQVITYGVIAGVVIFAPEIRAGLEK
                     FGRSTQVFLQKQSLSDEEMLVDALLKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVANNKIAAACAYLPLSESMSISKEFGTRHRAAI
                     GLSENSDAVTIIVSEETGAVSIARKGQFLHDLSTEELEAVLKTHLMNEPGATLPWYKK
                     ILGGKAK"
     gene            867..1823
                     /locus_tag="TV193_001488"
     CDS             867..1823
                     /locus_tag="TV193_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEL1513670.1"
                     /translation="MKRFLNSRLGLGLVSIFFAIILFLTAASSSHNHSNSQIYSPIET
                     YTHSLKDVPIDIKYDSDQYFISGYSYGAEVYLTSTNRIKLDSEVNSDTRSFKIVADLT
                     KSKPGTATVTLKVINLPTGVTATVSPDKISVTIGNKKTKTFPVRGSVDSKQLAKGYEI
                     SKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVAADGTILASA
                     IDPAKANLSVSVKKITKSVPIRVEAVGLMDDSLSDIQYKLSKQTAVISGSREVLETID
                     EVVAEVNISDVTKNTSKTVSLVSNQVSIEPSVVTVQLTTIKK"
     gene            1876..3228
                     /locus_tag="TV193_001489"
     CDS             1876..3228
                     /locus_tag="TV193_001489"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEL1513671.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRV
                     FVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKY
                     ERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGS
                     THPEKLQDLVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLA
                     KNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAI
                     AEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
                     "
     gene            3262..3948
                     /locus_tag="TV193_001490"
     CDS             3262..3948
                     /locus_tag="TV193_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1513672.1"
                     /translation="MLSSSIRIGGNMIKHRVDRIASQLDELTQKLYLTMIPEYQEGYA
                     NYIYQTDQPDVQRRRIKHINKTFHRLLSESSFYLMPMTQHSAEIIAHDWIYSPAYECY
                     SMTADPEDYQSILSPKARGEHYFQVLRNGVLFGFASFFEQESELEIGLGMAPDTTGQE
                     DGVSFLGSIEAFASTTYPQETYVLNVASFNKGAQSLYQKMGYQPTSSFEQYANGSSHS
                     FVRMEKKKQP"
     gene            4015..5145
                     /locus_tag="TV193_001491"
     CDS             4015..5145
                     /locus_tag="TV193_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEL1513673.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLEALIKE
                     FESYQISSLKTLYIGGGTPTAITANQLDYLLSHLQQHLQLDQLEEFTIEANPGDLTED
                     KIAVLRQSAVNRISLGVQTFNDKQLKQIGRSHTEAQIYTTIASLKEAGFQNMSIDLIY
                     ALPGQTMQQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEM
                     FEYIISEMEASGFEHYEISNFTKPGFESRHNLMYWNNDEYFGCGAGASGYLDGIRYRN
                     RVPIQHYLKAVADGNARLSEEVLTKEEMMEEELFLGLRKKSGVSVSRFQEKFGLSFES
                     RYGPVVRELQNQGLLVEDKDFIRMTKKGLFLGDSVAEKFILD"
     gene            5156..5908
                     /locus_tag="TV193_001492"
     CDS             5156..5908
                     /locus_tag="TV193_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEL1513674.1"
                     /translation="MGLRYSESLKLSFDFCDVKADVKLPLLLAHCLMVSARQSAEIGR
                     GNEVLLQQYGLIWVVTDYDVTIDRMPRFGETVTIETQAISYNKLFCYRQFHIYDQAGH
                     AIMTILSHFALLNPQTRKAAAIPDDLVVPYQADFVKKIKRPIKIDELQDPMVQAYQVR
                     YFDIDMNGHANNSKYLDWMYDVLGYEFLLHHRPCHLTLTYIKEVRPSTQITSGYHLEH
                     LTSYHEIRSSGQLNAQAIIKWQPITTKESETN"
     gene            5908..6675
                     /locus_tag="TV193_001493"
     CDS             5908..6675
                     /locus_tag="TV193_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEL1513675.1"
                     /translation="MPYKAYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQEMLANQFNVHTGLETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     EAGYTEDTENPAYVVVGLDTEVTYEMLSIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKALEILKVPRSEVAMVGDNYLTDIMAGIQN
                     DMATILVTTGFTKAKEVPSLPIKPDHVLASLDEWELL"
     gene            6672..7313
                     /locus_tag="TV193_001494"
     CDS             6672..7313
                     /locus_tag="TV193_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEL1513676.1"
                     /translation="MIEKGKFIASWLWLLALAVLITIYLSWLLYPIEVDYLQLEQAVL
                     MCKKSILHNYNILLTYLTNPFVRELKLASFSASRAGLKHFTDVKMLFHITQLIFSLLM
                     LPTIIYFYQSIKKGRVMLLRRGLIAAALLPIVIACFALMIGFDQFFTLFHQILFVGDS
                     SWLFDPLTDPVIWILPEAFFGHCFALFFFIYEMILWSLIGLSYSNQSSQVAYH"
     misc_feature    7445..7580
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            7609..8109
                     /locus_tag="TV193_001495"
     CDS             7609..8109
                     /locus_tag="TV193_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEL1513677.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAK
                     TAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     SKEGAA"
     gene            8174..8539
                     /gene="rplL"
                     /locus_tag="TV193_001496"
     CDS             8174..8539
                     /gene="rplL"
                     /locus_tag="TV193_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEL1513678.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            8821..9294
                     /gene="tnpA"
                     /locus_tag="TV193_001497"
     CDS             8821..9294
                     /gene="tnpA"
                     /locus_tag="TV193_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL1513679.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKSIYYKIRQDLIDIFRH
                     LCQYKGVEIIEGHMMPDHVHMLVLLPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYYVSTVGLNKRTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            9581..10046
                     /gene="tnpA"
                     /locus_tag="TV193_001498"
                     /pseudo
     CDS             9581..10046
                     /gene="tnpA"
                     /locus_tag="TV193_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT         3021 a         1865 c         2309 g         3001 t
ORIGIN      
        1 catagaaatg agaattgtat gagtaattta tcaagtattg acacaaaatt tttactaagc
       61 ctgattgatg accccttgat gttggtggtt catttgctgg atattttaat agtagcctat
      121 ttgatttacc gttttattaa atccttggca ggaactaaga tcatgtcctt ggtacaaggg
      181 gttatattct ttatcatcat tcgtgtgatt gccgagtgga tagggtttac gactataacc
      241 tatctgatga atcaggtcat cacctatgga gtgattgcag gtgtggtgat ttttgctccg
      301 gaaattcgag cggggcttga aaaatttggc cgatcaacac aggtattttt gcaaaagcaa
      361 agcttgagtg atgaggagat gctggttgat gcgctcttaa aatcagttgc ttatatggga
      421 ccgcggaaga ttggtgctct gattgctatt gagcaaacgc agaccttgca ggaatatatc
      481 gcaacaggaa ttcccctaaa tgctgatatt tctagtcagc tattgatcaa tatctttatc
      541 ccaaacacac cgctgcatga tggtgcggtc attgtggcta acaataaaat tgctgcagcc
      601 tgtgcttatc tccccttgtc tgaatcaatg tcgatttcca aagaatttgg aacacgtcac
      661 agagcagcaa ttggactttc agaaaattct gatgctgtaa cgataattgt ttctgaggag
      721 acaggagctg tctctatcgc tcgtaagggt caatttttac acgacctttc aacagaagag
      781 cttgaggcgg ttctcaagac tcatttgatg aatgagcccg gtgcgacatt accttggtat
      841 aaaaaaatct taggaggcaa agctaaatga agaggttttt aaatagtcgt cttgggctgg
      901 gcttagtgtc aatctttttt gcgattattc tttttttgac cgctgcttct agcagtcata
      961 atcattctaa ttctcaaatt tatagcccta ttgaaaccta cacccatagc ttaaaggacg
     1021 ttcctattga tatcaagtat gatagtgatc agtacttcat cagcggctat tcttacggtg
     1081 cagaggttta tctgacctct accaaccgca taaagctgga ttcagaggta aacagtgaca
     1141 ctagaagctt taagatcgta gctgatctaa caaagagtaa gccaggtact gcaacggtga
     1201 ccctaaaggt tatcaatcta cctactggtg tgacagcaac tgtttctcct gataagattt
     1261 cggtaacgat tggaaataag aaaacaaaga cctttccggt gcgtggcagc gtcgatagta
     1321 agcagctggc taagggctat gagattagca aaattgaaac aggtattgac aaggttgagg
     1381 tcacaagtga tgagtctact attgccttga tagatcatgt tgtcgctaaa ttacctgatg
     1441 atcaggtgct agatgctaat tatagcagcc gagtaaccct gcaggcagta gctgccgatg
     1501 gtaccatttt agctagtgcg atcgatccag ccaaggctaa tttgtcagtt tctgtcaaaa
     1561 aaatcaccaa atcagttcct attcgagtcg aggcagttgg actaatggat gacagtctgt
     1621 cagatatcca gtataagctc tccaagcaga ccgctgttat ttctggtagt cgggaggtcc
     1681 ttgaaactat tgatgaggtg gtggcagagg tcaatatttc tgacgtcacc aaaaacacga
     1741 gcaaaacggt cagcttggtt tcaaatcagg tttctataga gccttcggta gtaaccgttc
     1801 agttgacaac aattaaaaaa taaagcataa tagctaggaa aatggaatgg aggaagcgtt
     1861 tagctgatat aaattatggg aaaatatttt ggaacggatg gtgttcgagg cgaggctaat
     1921 gtagagttga ccccagagct tgcttttaag cttggtcggt tcggtggtta tgtgctaagt
     1981 cagcatgaga ctgaaaggcc tagagttttt gtcgctcgtg acacccgtat ctctggtgaa
     2041 atgctagagg cagccctgat tgctggcttg ctttctgttg ggatagaggt ctataagctt
     2101 ggtgttcttg caactcctgg tgtgtcctat ttggtccgta cagaaaaggc tagtgctggt
     2161 gtcatgattt cagctagtca caatcctgct cttgacaatg gcattaagtt ttttgggagt
     2221 gatggcttta aattggctga tgagcaagag ctagaaatcg aagcgctctt agatgccaaa
     2281 gaggacctcc taccacgtcc aagtgcggag ggcttaggag ccttggttga ttatccagaa
     2341 ggcttgcgca agtacgagag attcttggtt actactggag cagatttaga cggtttaaag
     2401 atagctcttg atactgctaa cggtgcagct tctgtttcag ctcgtaatgt ctttttagat
     2461 ttaaatgcag acattacagt tattggtgag aatccaaatg gattaaacat taatgatggt
     2521 atcggctcta cacaccctga aaagcttcag gacttggtga cagaaacagc ctctgatatt
     2581 ggattggctt ttgatggcga tagtgatcgt ttaattgctg ttgatgaaaa tggtgctatt
     2641 gttgatggcg acaagatcat gtttatcata ggcaagtatc tttctgagaa gggcttgcta
     2701 gctaaaaata cgattgtgac aacagtgatg tctaaccttg gttttcacaa ggcattagat
     2761 agctgtggca ttcataagaa ggtaacagct gttggtgatc gttacgttgt tgaggagatg
     2821 cgtcagttcg gctacaatct tggtggtgag caatcagggc atgtcattat catggattac
     2881 aatacaactg gtgatggtca actgacagct gttcagctca ccaaaatcat gaaggagaca
     2941 ggtaaaactc tctccgaatt ggccagtgag gtcactattt acccacaaaa gcttgttaat
     3001 attcgtgttg acaacagcat gaaggagcgt gctatggaag tgcctgctat tgctgaggtt
     3061 attgctcaga tggaaggaga aatggctggt aatggtcgca ttttggtaag gcctagcggc
     3121 acagagccat tgttgcgtgt gatggcagag gcaccaagca atgaagaagt tgactattat
     3181 gttgatacca ttgcagcggt tgttcgtgcg gaaattggcc ttgattaatc tagaaaaagt
     3241 gtcgttgctt cggcactttt tatgctatca agcagcatta gaattggagg taatatgata
     3301 aagcatagag tggataggat tgctagtcag cttgatgagt tgacccaaaa gctgtatttg
     3361 acaatgattc cagaatatca ggagggctat gctaattaca tttatcaaac agatcagcct
     3421 gatgtgcagc ggcgtcgcat aaagcatatc aacaagacct ttcatcgctt attgtctgag
     3481 tcttcttttt acctgatgcc gatgacacag catagtgctg aaatcattgc gcatgactgg
     3541 atctatagcc cagcttatga gtgctatagc atgactgctg atcctgagga ctatcagtca
     3601 atattgtcac ccaaggcgcg tggagagcat tactttcaag tgcttcgcaa tggtgttctt
     3661 tttggctttg ccagcttttt tgaacaggaa tcagagcttg agattggtct tggtatggcc
     3721 cctgatacta ctggtcagga agatggtgtt tcttttttgg gcagcattga agcctttgct
     3781 agcactactt atccgcaaga aacctatgtt ttaaatgtcg ctagctttaa taaaggcgca
     3841 caaagcctct accaaaaaat gggctatcag ccaacctcaa gctttgagca gtatgctaat
     3901 gggagtagtc attcctttgt gagaatggag aaaaagaagc agccttaggt tagtacatgt
     3961 caaaaagcta atcacttggc atgaatttct gagctaaaat gatataatat taccatgtca
     4021 aaaaaaccaa cctcagccta tgtgcatatt cctttttgca cacaaatttg ctactattgt
     4081 gatttttcta aggtatttat caaaaatcag cctgtcgatg cctacctaga ggcactgatt
     4141 aaggaatttg aatcctatca gatcagctcc ttgaagacac tttatattgg cggtggaaca
     4201 ccaacagcca taacagccaa tcagcttgat tatttgctga gccatttgca gcagcaccta
     4261 cagctagacc agcttgaaga atttaccatc gaggccaatc caggtgattt gactgaggat
     4321 aagattgcag tattaaggca atcggctgtc aatcggattt ccctaggcgt tcaaactttt
     4381 aatgacaagc aattaaagca gattggacgc agtcatactg aggctcagat ttatacgacc
     4441 attgctagtc ttaaggaggc aggctttcaa aatatgtcta tcgatctcat ttatgctttg
     4501 cctggacaga ccatgcagca ggtcaaggaa aatgtggcta aggcacttgc tttagatatt
     4561 cctcacctta gcctgtatag ccttatccta gagcatcaca ctgtttttat gaacaaaatg
     4621 cgtcgtggca agctccattt gcccactgag gatttggaag ctgagatgtt tgagtatatt
     4681 atttctgaaa tggaagccag tggctttgag cattacgaaa tttctaattt tactaagcct
     4741 ggctttgaaa gcaggcacaa tctgatgtat tggaataatg atgagtattt tggctgtggc
     4801 gcaggggctt ctggctatct tgatgggatt cgttaccgca accgggttcc tattcagcat
     4861 tacctaaagg cagtagcaga tggaaatgct aggttaagtg aggaagtgct caccaaggag
     4921 gagatgatgg aggaggagct ttttcttggt ctgcgaaaaa aatcaggagt atcagtcagt
     4981 cggtttcaag aaaaatttgg cctatcattt gagtcacgct atggtcctgt tgtgagagag
     5041 cttcagaatc aggggctttt ggtagaggac aaggacttta tcagaatgac caaaaaaggc
     5101 ctctttttag gtgattctgt cgctgaaaaa ttcatcttag attaggaggt gtgttatggg
     5161 attaaggtat agcgaaagcc ttaagctgtc ttttgatttt tgtgatgtta aggctgatgt
     5221 caagctgccc cttttattag cacattgctt aatggtatca gcaagacaat cagctgaaat
     5281 tggacgaggc aatgaggtgt tacttcagca atatggcttg atttgggttg ttacggatta
     5341 tgatgtaacg attgatcgta tgccaaggtt tggggaaaca gtaaccattg aaacgcaagc
     5401 tatttcttac aataaattat tttgttaccg gcaatttcac atttatgatc aggcaggtca
     5461 tgccatcatg accattttat ctcattttgc cctgctaaat cctcaaacac gtaaggcagc
     5521 tgcgatacca gatgatttgg tggtgcctta tcaggctgac tttgttaaga aaatcaagcg
     5581 tcctatcaaa atagatgagc ttcaggatcc tatggttcaa gcttatcagg ttcgttattt
     5641 tgacattgat atgaatggtc atgccaataa tagtaagtat ttggattgga tgtatgacgt
     5701 tttgggatat gaatttttat tacaccacag accttgccac cttaccttga cctatatcaa
     5761 agaggtgagg cccagcactc aaataacctc aggctatcat ctagagcatt tgacctccta
     5821 ccatgagatc aggtcatcag gccagcttaa tgcgcaggcc attatcaaat ggcagcctat
     5881 aacgactaaa gaaagtgaga caaattagtg ccctataaag cttatttaat tgatttagat
     5941 ggaaccatct atcaagggaa aaatcgtatc ccggctggtg agcgctttat caagcgttta
     6001 caggaaaaag gtatccctta tctcttagtt accaacaaca ccacaagaac acctgaaatg
     6061 gttcaggaaa tgctagccaa tcaatttaac gttcatacag gtcttgaaac catttacacc
     6121 gctacaatgg caaccgttga ttacatgaat gatatgaatc gaggcaaaac agcctatgtg
     6181 attggcgaga ctggcttaaa gtctgccatt gcagaggcag gctataccga ggatacagaa
     6241 aatccagcct atgttgttgt tggcttagat actgaggtta cctatgaaat gttatcaatt
     6301 gcaacacttg ccattcaaaa aggagccttg tttattggga ccaatcctga cttaaatatt
     6361 ccaacagagc gtgggctaat gccaggtgct ggcgctttaa atgcgctcct tgaggcagca
     6421 actagagtga agccagtatt tataggaaag ccaaatgcga ttatcatgaa taaagcccta
     6481 gagatcttaa aggtaccacg ttctgaggtg gctatggttg gagacaatta cctgacagat
     6541 atcatggcag gaattcaaaa tgatatggca actattctag taacaaccgg ctttacaaag
     6601 gcaaaagagg ttccaagcct tccaattaag cctgatcatg tcttggctag cttagatgag
     6661 tgggagctat tatgattgaa aaaggcaagt tcattgccag ttggctttgg ctactagcac
     6721 tggcagtttt gataactatc tatttatctt ggctgcttta tccgattgag gttgattatt
     6781 tgcaactaga gcaggcagtt ttgatgtgca aaaagtctat tctccacaac tataatatat
     6841 tgctgactta cttaaccaat ccttttgttc gtgagctaaa gctagccagc ttttcagcat
     6901 caagagctgg tctaaagcat tttacagatg tgaaaatgct gtttcatata acacagctga
     6961 tctttagcct gcttatgttg ccaaccatta tctattttta tcagagcatc aaaaaaggaa
     7021 gggttatgct gcttcgaaga gggctaatag cagcagcctt attgccaatt gtgattgctt
     7081 gctttgcttt aatgattggc tttgatcagt tctttaccct ttttcatcaa attctctttg
     7141 taggagattc aagctggttg tttgatccgc tgacagatcc tgtcatttgg attttgccag
     7201 aggccttttt tgggcattgc tttgccttgt tcttctttat ttatgagatg atactgtgga
     7261 gcttgatcgg gctaagttat agcaatcaat cgtcacaagt tgcttatcat taggcttaag
     7321 ttaggaggcg cttttgagcc actaatcaga tctatttagc ggaaagccaa gagctttcct
     7381 tttttattta agattttcta aaaaataggt tgacaaagtc atttaaaaag gctatactaa
     7441 ctatggtttt gaataaaact gacctaagac agcaggggag cgtgctcata atattcctgc
     7501 cgaggcacaa aacgtcatta ttgaagataa cgtatttgta ctttcgtgtc taggtttagg
     7561 tgcgattttt ttgtgcctag cccaaaaata aaaacggagg taaaactaat gagtgaagca
     7621 attatcgcta aaaaagctga acaagttgag cttatcgctg agaaaatgaa agcagctgta
     7681 agtatcgttg ttgtagattc acgtggtctt acagttgatc aagatactgt tcttcgtcgt
     7741 tcacttcgtg aaagtggcgt tgagttcaag gttatcaaaa actcaatctt gactcgtgca
     7801 gctgaaaaag caggtcttga cgagctaaaa gatatattcg taggaccatc tgcagtagca
     7861 ttttcaaatg aagatgttat cgcaccagct aaagtcatca acgactttgc taaaactgct
     7921 gaagcacttg agattaaagg tggtgctatc gaaggtgttg tttcttcaaa agaggaaatt
     7981 caagcacttg cagcattgcc aaaccgcgaa ggaatgcttt ctatgcttct ttctgtactt
     8041 caagctccag tccgcaacgt tgcatacgct gtcaaggctg ttgcagaaag caaagaaggc
     8101 gctgcgtaag gcctttagag gtagcctaga gctacaaatc attatttaat ataactattt
     8161 ggaggaaatg acaatggcat taaacattga aaacattatt gctgaaatta aagaagcttc
     8221 aatccttgag cttaacgatc ttgtaaaagc tatcgaagaa gaattcggtg tgactgcagc
     8281 tgctcctgta gctgtagctg ctgctggtgg tgctgaagaa gctactaagg attcatttga
     8341 cgttgagttg acatctgctg gtgacaaaaa agttggtgtt atcaaggcag ttcgtgaaat
     8401 cacaggtctt ggacttaaag aagctaaagg tcttgttgac ggcgcacctg ctaacatcaa
     8461 agaaggtgtt gcagcagcag aagcagaaga aatcaaagct aagcttgaag aagctggagc
     8521 aactatcact cttaaataat agagtatcgc aatttgattg cggaagccta gtaaatcaag
     8581 gtttaatgat tgcttagagc gatttagaga aactgataaa ttgatttggt ttcctgctaa
     8641 aaaccctacc aaagattttt tggcagggtt tttattttta ttatggcttc gagccagttt
     8701 ttctcgtaga gaaaaacaag aaaaccacca gctatgctgg tggctgacaa ggctttgagc
     8761 ttccatttct ttttcctgtt ataatctaat tgttcaggtt agatcaagga ggaaaaagag
     8821 atggctaaaa ccagttacag tttatcacat accaaatgga tgtgcaaata tcacatagtt
     8881 ttcacaccaa agtaccgcag aaaatccatt tactacaaaa ttagacagga cttaattgat
     8941 attttccgtc acctatgtca atacaagggc gtggaaatca ttgagggaca tatgatgcca
     9001 gatcatgttc atatgctcgt cttgctacct ccaaaacttt cgatttccga tttcatgggg
     9061 tatttgaaaa gtaaaagtgc tctcatgata tttgataaac acgctaattt aaaatataag
     9121 tatggaaatc gaaagttttg ggctagaggc tactatgtta gtaccgttgg actgaacaaa
     9181 aggacggtag cgaaatatat tcgcgagcag gagaaaaatg acattgcact tgataagttg
     9241 agtgttaaag aatatgaaga tccattttca gatggcagtt ttaaaacaag ataaaagccc
     9301 gtttttacgg gcattagtca agtaatcata gcactaacct gaacgaagtt cagcgaacgt
     9361 ctttagacgt cgctggagag aaacggctta tagccggtgt acaagccacc cgtttttacg
     9421 cgtggttatg acttagtgac tttagtccgt ttcgctccgt aggtgcgaaa caaaaatccc
     9481 ccgctatgcg ggtacgcatc gaacgttata ctacaaaaaa actccaaacg cgctacaata
     9541 taggtgttca agccaattgt aaagcgaaag gagtaaaaat atggcacaaa agccccacag
     9601 tttatcgcac acaaagtagc attgtaaata tcacattgtg ttcaccccta agtatagacg
     9661 aaaagtaatc tataatcaat atcgaggcag tttgggagaa atttttcaaa gattatgtag
     9721 ctataaaggt gtagaaatat atagaaggac atctgatgcc agatcacgta cacgtgttag
     9781 taagcattcc acccagaata agtgtttcaa gttttatagg atatttaaaa ggtaagagta
     9841 cgcttatgat gttcgacaag cacgccaatc tgaaatacaa atttggtaat cgacactttt
     9901 gggcagaagg ctattatatt agtacggttg gattaaatga agctacaata aaaaaatata
     9961 ttcaagaaca agaaaaacat gacatagcac tagataaact gagtgtaaaa gaatatgagg
    10021 atccctttag agataagggt aagtgataca aatacttctt tgagaggcaa gtgacgagtc
    10081 aatagcaatg tggtttgaac aaagtgaaag ccagcgtctt taggcgctgg ctagttatat
    10141 gggtttatag tccctattca aaccacctgt tggacgggtg gttatgattt ctacta
//
LOCUS       DARYXS010000074         9703 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.075, whole genome shotgun sequence.
ACCESSION   DARYXS010000074 DARYXS010000000
VERSION     DARYXS010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9703
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.075"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(4..1239)
                     /locus_tag="TV193_001499"
     CDS             complement(4..1239)
                     /locus_tag="TV193_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1513680.1"
                     /translation="MKKLIVTLAALMCLITNTSFAENFSVNSRQAIAVEMTTGKILYA
                     KEAQQKAPIASLTKLLTVYLVLKEIKAGRLQWDSQVTLSEYALQLATDPDISNPAFEQ
                     RPYTIKELVESSLIISANSSAVALAEHIAGSEPTFVDMMKKQLEAWGIRDYLLVNASG
                     LNNSMLKGHLYPGSQPDDENQMTARDLALIAQQLIQDFPELLTISSQPQLKWGEKALP
                     SSNLLLAGREMGRAGVDGLKTGTTSQAGQTMIATAVQDNMRVISVILHADQSDTDERA
                     RFVETNRLLDYCFNSYALEKLVAQNQVLPERLIVKQAAKQRLRVKASQTLTVVRPKDQ
                     TELSYSLRIKDKALKAPIRQNKKVGTLIYQDPKLIDSGYLAAPPAVAIVSAKSIPEKG
                     KLSKLFDFFQKVIGILINP"
     gene            complement(1561..2799)
                     /locus_tag="TV193_001500"
     CDS             complement(1561..2799)
                     /locus_tag="TV193_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1513681.1"
                     /translation="MKKVLIALTILAISCLAYPAQADHYDISAKHAIAVELDSGKILY
                     EKDADKTVSVASLSKVLTAYLVYKEVQAGKLKWDSSVTISNYPYKLTTNYTISNVPLD
                     ARKYTVKELLKALIVTNANSPAIALAEKIGGTEAKFVDKMIAQLKDWGITGAKVVNAS
                     GLPNHILGEHIYPGSSLDDDNQFSAADLALVTSHLLKEFPEVLKLSSQVQAEFNHQQI
                     FSYNYMLKGMPNYRDGVDGLFVSYSEKGGSSFLATSVENNMRIITVVLNADHAQDNDT
                     AVFTATNQLLQYVLTHFKKVVVLEKGKPDQLKALPVLDSPQKKIQLVPKKKLTMIKAL
                     DDKSKTTFQVSDTKNPLVAPIQKGQTLAKATLNDHSLIGKGYLGQAPSVELVAQKKVP
                     KSFFLKVWWNHFVRYVNQYL"
     gene            3107..5083
                     /locus_tag="TV193_001501"
     CDS             3107..5083
                     /locus_tag="TV193_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1513682.1"
                     /translation="MKKSKWLATLGVAALSVSILAACGNSSSKSSESKIYSYVYSSDP
                     STLDYISTSKATTNDITTNAVDGLLENDQYGNLIPSLAKDWKVSKDGLTYTYTLRDGI
                     KWYTSDGEEYADVTAEDFVAGVKHAADVNSDALYIIQDSIKGLSDYLNGKTKDFSTVG
                     VKALDKKTVQYTLNQPESFWNSKLTYSVLAPVNADFLKSKGKDFGKATDPSSILYNGP
                     FLITALTSKSSIELVKNENYWDAKNVHLDGVQLTFYDGQDQESLFRNFDDGAYSAARL
                     FPTTPSYKTVKKKYGDSITYGQQNATLYYAAFNLNRTSYNHTKKTSDSQKSDTQKAIL
                     NKDFRQAMTFAFDRIAYQAQSAGEDAANKSLRSTLVPPTFVKIGDKNFGDVVEEHLVT
                     YGSQWENVNLDDAQDGLYNPEKAKASFEKAKAALQAEGVQFPIHLDYPMDQTATVLLQ
                     QARSMKQSIEKTLGTDNVVIDIIELQKDVYENISYLAETPAQNDWDISTASGWGPDYV
                     DPSSYLDIFNPTLANSQTKSIGLEPGKDLAIASAAGLDEFTKLVTEAGKITDDLNARY
                     TLYAKAQAALTDSAIYIPTISLGGTPRVTKVVPFSGAFAWAGTKNDFYYKYVKLQDKP
                     VTAKQYDKALAEWKKEKKKSNEKYNNSLEKHIEK"
     gene            5147..6646
                     /locus_tag="TV193_001502"
     CDS             5147..6646
                     /locus_tag="TV193_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513683.1"
                     /translation="MKKYIFERILRSLVSILLVTALTYTIVFTLVPKSLIFKQDPNYN
                     KMVTTPDKKTNYLNTVFENMGYISYYSSKELQNKASKLDPSVTTAPTKANEKIYQKYI
                     ASVGNGWKLGRFTESKGFYAVREIPIYERVWNFFSHLVVIDHPWKIKDPKNPNLERYV
                     RPEIDPAVGPALVGSGTKHKYLIYFNKQFPFIHQNIVTFDLGVSYPTYANIPVVQVIT
                     QGQGRTLQKEVTFPTGKTKLSSIDIYSRTYKTPSSLDSKDIANFGKGDAYTNTQNNYA
                     EPSMIANSFKIGIVGVLLSYLFGLPIGMLMAYYKNGWFDRFSTAATTFMLALPSIALI
                     YIVRFVGSYLGLPDTFPLLGAGDVRSYVLPALILGILGTPSTVVWFRRYIVDLQGSDF
                     VRFARAKGLSEFEISKNHLFKQAMVPIVNGIPQAIVGTIAGATLTETVFAFPGMGKML
                     IDSIKAANNSMVVGLVFIFAVLSILALLVGDILMTILDPRIKLSGKGGK"
     gene            6646..7572
                     /locus_tag="TV193_001503"
     CDS             6646..7572
                     /locus_tag="TV193_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513684.1"
                     /translation="MAAIDKNKFTFVELDSYASEVIDAPAYSYWKSVFRQFFSRKSTI
                     LMLVILIAIILMSFIYPMFANYDFGNVSNINDFSKRYIAPNAEYWFGTDQNGQSLFDG
                     VWYGARNSILISVIATIINMIIGVIVGGIWGVSKAVDKVMIEVYNIISNLPQMLIIIV
                     LTYSIGAGFWNLIFAFCVTGWIGIAYSIRVQILRYRDLEYNLASQTLGTPTHKIVIKN
                     LLPQLVSVIVSMVSLLLPSYISSEAFLSFFGLGLPITEPSLGRLISNYSNNLTTNAYL
                     FWIPLTTLILVSLPLYIVGQNLADASDPRTHR"
     gene            7581..8651
                     /locus_tag="TV193_001504"
     CDS             7581..8651
                     /locus_tag="TV193_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513685.1"
                     /translation="MTEKQEIILSAKNIVVEFDVRDRVLTAIRDVSLDLYKGEVLAVV
                     GESGSGKSVLTKTFTGMLEANGRVASGTITYAGQELTELKNHKDWEAIRGSKIATIFQ
                     DPMTSLDPIQTIGSQITEVIVKHQKKSRSEAKALAIDYMTRVGIPEPEKRFGEYPFQY
                     SGGMRQRIVIAIALACKPDILICDEPTTALDVTIQAQIIDLLKTLQKEYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIIEYGKVEEIFYDPRHPYTWSLLSSLPQLADEKGVLFSI
                     PGAPPSLYKPIVGDAFAPRSQYAMAIDFEETVPRFTISDTHWAKTWLLHPDAPKVQKP
                     AVIQDLHQKILKKMSRQEEGNV"
     gene            8644..9567
                     /locus_tag="TV193_001505"
     CDS             8644..9567
                     /locus_tag="TV193_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513686.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNETSSGEIRYDGKIINGKKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEDERKEKIKQMMSEVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMDPEFVIADEPISALDVSVRAQVLNLLKKIQSEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFVNPVHPYTKSLLSAVPIPDPILERQKKLVVYHPEQHD
                     YSVDKPSMVEIKPNHFVWANQVEAERYRKEL"
BASE COUNT         2876 a         1900 c         2016 g         2911 t
ORIGIN      
        1 atattaaggg ttaatgagaa tgccaatgac tttttgaaaa aagtcaaata atttgctaag
       61 tttccctttt tcaggaatgc ttttagctga gacaatagca acagctggcg gtgctgctag
      121 atagccactg tcaatgagct taggatcctg atagataagg gtaccgacct ttttattttg
      181 acgaattggg gccttgagtg ctttgtcttt gattcgtagc gagtaagaca gctctgtctg
      241 gtccttaggc cgaacaaccg ttaaggtttg actagccttg acccttagcc tttgctttgc
      301 tgcttgttta acaatcagtc tttcaggcaa aacttggttt tgagcaacaa gcttttccaa
      361 ggcatagcta ttaaagcaat aatcaagcag gcgattggtc tcaacaaagc gagctcgctc
      421 atcagtgtca gattgatcag catggagaat gacagaaata actcgcatat tatcctgcac
      481 agctgttgca atcattgttt gtccggcttg gctggtagtg cctgttttaa ggccatcaac
      541 cccagctctg cccatctcgc gaccggctaa tagtagatta gaactaggca aggccttttc
      601 accccatttc aattggggct gtgaggagat ggtgagaagc tcaggaaagt cttgaatcaa
      661 ctgctgtgca atcagtgcca gatctctagc tgtcatctga ttttcatcat ctggctgtga
      721 gcctggatat agatgcccct ttagcatact gttgtttagc cctgaagcat tgacaagaag
      781 atagtctcta atcccccaag cctccagctg ttttttcatc atgtctacaa atgtaggctc
      841 tgagccagcg atatgctctg ctagagctac agcagagcta ttagcactaa taatcaggct
      901 agattcaaca agctctttga tagtgtaagg tctttgctca aatgctgggt tgctgatatc
      961 aggatcagtg gctaattgca gagcatattc agatagggtt acctgactat cccactggag
     1021 ccgtcctgcc ttaatttcct tcaggactag gtagacggtt agtagctttg ttagagaagc
     1081 aatgggcgcc ttttgctggg cctctttggc atataggatt tttccagttg tcatttcaac
     1141 cgcaatggct tgacgactat taacagagaa gttctcagca aaggaagtat ttgtgatcag
     1201 acacatgagc gcagcaagtg tcacaataag ttttttcata ccatcattgt agcaaggaaa
     1261 tagtgatcgg tcaaaaggtc attgagtacc tttaaagaag gctaagtcaa gactctgagt
     1321 gagatgacgt ccccaaaaat caagcctcaa aaaaaccgtc tgacatcaac agactaaagc
     1381 tgtcaattca tacggttttg ctgtttgcag agcttttgta ggccttagag cttgctagga
     1441 gctcttttag ctaccttctt ggagagcttg acacaatggt caatttttgc gagataagcc
     1501 taatgaagcc ctgagtgagg ccttggcact aatgaggaca taaggcataa aagctagtca
     1561 ttagagatat tggttaacat aacgaacaaa atgattccac cagaccttta aaaagaagct
     1621 ttttggcacc tttttttgag ccaccagctc aacgcttggc gcttgaccta gatagccttt
     1681 tccgattaag ctatgatcat taagtgtggc ctttgcgagt gtttgtcctt tttggatagg
     1741 cgctactaag ggatttttgg tatcgcttac ttgaaaagtc gttttggact tgtcgtcaag
     1801 cgcttttatc atagtgagct tcttttttgg cactagctgg atcttctttt gaggactatc
     1861 taaaacagga agcgctttaa gctgatctgg tttacccttt tcaaggacaa caaccttttt
     1921 aaaatgcgtc aaaacatact gcagcaattg gtttgtcgct gtaaagacgg ccgtatcgtt
     1981 gtcctgggca tggtcagcat tgaggacaac tgtaataata cgcatattgt tttcgacact
     2041 agtggctaaa aaagaagagc ctcccttttc agaatagcta acaaaaagcc catcaacacc
     2101 atcacgatag ttaggcattc cctttagcat atagttgtat gaaaaaatct gttgatgatt
     2161 aaactcagct tgaacctgac ttgatagctt taaaacctca ggaaattcct ttaaaagatg
     2221 gctagtgaca agagcaagat cggctgcact aaattgatta tcatcatcaa gactagatcc
     2281 cggatagata tgctctccta gtatgtggtt aggcaggcca ctagcattga cgaccttggc
     2341 acctgtaatg ccccagtctt tcaattgagc gatcatttta tcaacaaact tagcctctgt
     2401 tcccccgatt ttttctgcca gggcaatagc agggctatta gcattggtga caataagagc
     2461 ctttaacagc tctttaacag tatattttct agcatctaag ggcacattgc ttatggtgta
     2521 gttggtggtt agtttgtaag ggtagttaga gatcgttacg gagctatccc attttaactt
     2581 tcctgcttgc acctctttgt acaccaaata agctgttaaa accttgctta gagaagccac
     2641 agaaacagtc ttgtcggcgt ccttttcgta tagaatctta ccgctatcaa gctcaacagc
     2701 aatcgcatgc ttggcgctaa tatcataatg atcagcctgt gctggatagg ccagacaaga
     2761 tatggctaat atggtcaaag ctattaaaac ctttttcatt tgaataatcc ttctagtcgt
     2821 ttttttaatt ataccataat ttttcaagaa gcttgactaa acctctcaga gaagagagat
     2881 cattatgaga aaatgctagc tgttatgata gcgataacga actgtataaa aatagcaaat
     2941 aatgtatctt aaacgtcatc agatcgtcaa cagaaaaaat cttgcaaaat attcagataa
     3001 ttttgcgatc gctatttcca tcagctaaaa tttgtggtat aatagctcca attaaccaat
     3061 ttcatttatg ctgataaatg aaaaataacg tttaggggtg acttctatga agaaaagtaa
     3121 atggttggca acgctgggtg tcgcagcgct gtcggtgtcc atcctggcag cctgtggaaa
     3181 cagctcaagt aaaagcagtg aatcaaagat ttatagctat gtctattcta gtgatccaag
     3241 tactttagac tatatcagta caagtaaagc aacaacaaat gacataacaa caaatgctgt
     3301 tgatgggctt ttggaaaatg accaatatgg gaatttaatc ccctctcttg ctaaggattg
     3361 gaaggtctca aaggacggct tgacctatac ctacacgctt cgtgatggga ttaagtggta
     3421 cacatctgat ggagaagagt atgcagatgt gacagctgag gattttgtag ctggagtaaa
     3481 gcacgcagca gatgttaact ctgatgccct atatatcatt caggactcta ttaaaggctt
     3541 aagcgattac ttgaacggta agaccaagga cttttcaacc gtaggtgtca aagcgcttga
     3601 caaaaaaaca gttcagtaca cccttaatca accagaaagc ttctggaatt caaagctaac
     3661 ctatagtgtc ctagctccgg taaatgctga cttcttaaaa tcaaagggca aggattttgg
     3721 taaggcaaca gatccatcat ctatcctgta taatggtcca tttcttatca cagctttgac
     3781 aagcaaatcc tctatcgagc ttgtcaaaaa cgaaaattat tgggacgcta agaatgttca
     3841 ccttgatggt gttcaattga ccttttacga tggacaggat caggagtcat tgtttagaaa
     3901 ctttgatgac ggtgcttact cagcagcgag attattccca acaacacctt cttataaaac
     3961 tgttaagaaa aaatatggag acagcatcac ttacggacaa caaaatgcta ctctctacta
     4021 tgcggcgttt aacctaaatc gtacgtctta caaccacact aagaagacct cagatagcca
     4081 aaaatcagat acccaaaagg ctatcttaaa caaggatttc cgtcaggcta tgacatttgc
     4141 ctttgataga attgcttatc aggcgcaatc agcaggtgaa gatgcagcta acaaatcgct
     4201 tcgtagcaca cttgtgccac cgacatttgt gaaaattggc gacaaaaact ttggtgatgt
     4261 tgttgaggag cacttggtga cctatggtag ccagtgggaa aatgtaaatc tagatgatgc
     4321 acaggatggc ttgtacaatc ctgaaaaggc aaaagcatca tttgaaaaag caaaagcagc
     4381 cctacaagct gagggtgtac agttcccaat ccatcttgat tacccaatgg atcaaactgc
     4441 aacggtgctc ttacagcagg ctcgctctat gaagcagtca attgagaaaa cattaggaac
     4501 tgacaatgtt gtgattgata ttattgagct tcagaaagat gtttatgaaa atattagtta
     4561 tctcgccgaa actcctgctc aaaatgactg ggatatttca acggcttctg gctggggacc
     4621 tgattatgtc gacccatcgt catatcttga tattttcaac ccaacgcttg caaactcaca
     4681 aacaaaatca attggacttg agccaggtaa ggatttggcc attgctagtg cagctggctt
     4741 agacgaattt acaaagctag tgacagaggc aggcaagatt actgatgatc tcaacgcccg
     4801 ctacacgctc tatgctaagg ctcaagcggc attgacagac tctgctattt acatcccgac
     4861 tatttcactt ggtggaacac cacgtgtaac taaagtggta ccgttttcag gcgcctttgc
     4921 ttgggctggt actaaaaatg acttttatta caaatacgtc aagctacaag ataagcctgt
     4981 aactgctaaa caatatgaca aagcattagc cgagtggaaa aaagaaaaga aaaaatctaa
     5041 cgaaaaatat aataattccc tcgagaagca tattgaaaaa taaattgatg ttcattaaga
     5101 actttctctt agaggaggaa gttcttttga actgctgggg actagaatga aaaaatacat
     5161 atttgaacgc atattgaggt cgcttgtttc aatcctgctg gtaaccgcac taacctatac
     5221 tattgtcttt accttagtgc caaaaagctt gatttttaag caagacccta attacaataa
     5281 aatggtgaca acacctgata agaaaaccaa ttatctaaat actgtttttg aaaatatggg
     5341 ctatatttcc tattacagca gtaaagaact gcagaataag gcttcaaagc ttgatccttc
     5401 tgtaacaact gcaccaacca aggccaatga aaaaatatat caaaaatata ttgcttctgt
     5461 cggtaatggt tggaagcttg ggcgctttac agaaagtaag ggattttatg ccgttagaga
     5521 gattccaatc tatgagcgcg tgtggaattt ctttagccat ttggttgtga ttgatcaccc
     5581 atggaaaatc aaggatccaa aaaatccaaa tctagagcgt tatgtgcgac cagaaattga
     5641 ccctgctgtt ggtccagcct tagttggctc tggtactaag cacaaatact tgatttactt
     5701 caacaagcaa tttccattta tccatcaaaa tatcgtaacc tttgatttgg gagtgtccta
     5761 tccaacctat gccaatattc cagttgttca ggttatcact caaggacaag gaagaacact
     5821 tcaaaaagag gtcaccttcc caacaggcaa aacaaagctg tcttcaatcg atatttactc
     5881 tcgaacctat aaaacaccaa gctctttaga tagcaaggat attgccaatt ttggtaaggg
     5941 tgatgcttat accaatacac aaaataacta tgcagagcca tctatgattg caaattcctt
     6001 taagattggt attgtcggtg tcttgttgtc ctatcttttt ggtttgccaa ttggtatgct
     6061 gatggcttat tataagaatg gctggtttga ccgcttttca acggctgcca caacctttat
     6121 gttagccctg ccaagcattg cgcttatcta tattgttcga tttgtcggtt cttatttggg
     6181 cttgccagat acctttccgc tgctaggagc aggagatgtt aggtcttatg tgctgcctgc
     6241 tcttatatta ggaattcttg gtacaccaag tacagtagtt tggttccgac gctatattgt
     6301 ggacttgcaa ggcagtgatt ttgttcgctt tgcacgagca aaggggcttt cagaatttga
     6361 gatttcaaaa aatcatctct ttaagcaggc tatggtgcct attgttaacg gtattccaca
     6421 agccattgtc ggaacaattg ccggtgcaac cttgacagaa accgtctttg ctttcccagg
     6481 aatgggtaaa atgctgattg attccataaa agctgctaat aactctatgg ttgttggtct
     6541 tgtctttatt tttgctgttt tatcaatatt agccttgcta gtaggtgata ttcttatgac
     6601 aattttagat ccacgtatta aattatcagg taaaggaggt aagtaatggc agcaattgac
     6661 aaaaataaat tcacctttgt tgaattagat agctatgcat cagaagtcat tgatgcccct
     6721 gcttactctt attggaaatc tgtatttaga caatttttct cacgtaaatc aactattttg
     6781 atgctggtta ttttgattgc tattattttg atgagcttca tctaccctat gtttgccaac
     6841 tatgactttg gtaacgtgag caatattaat gatttttcaa aacgttatat agcacctaat
     6901 gcagagtatt ggtttggtac ggatcaaaat ggtcaatcgc tctttgatgg cgtttggtat
     6961 ggtgctagaa attcaatctt aatttcagtt attgcaacca tcatcaatat gattatcgga
     7021 gtcattgtcg gtggtatttg gggtgtttcc aaagcagttg ataaggtaat gattgaggtg
     7081 tataatatca tctctaacct gccgcaaatg ctcattatca ttgtgttgac ttattctatc
     7141 ggagcaggct tttggaactt gatttttgct ttttgtgtga caggctggat tgggattgct
     7201 tattcgattc gtgtacaaat tttgcgttat cgtgatttag aatacaattt agcaagtcag
     7261 accttaggaa cacccaccca taaaattgtc attaaaaatc ttttacctca attggtttcg
     7321 gtgatcgttt cgatggtttc cttgctattg ccgtcctata tttcatcaga ggccttctta
     7381 tccttctttg gcttgggatt accaatcaca gaaccaagct tgggtcgatt gatttcaaat
     7441 tattcaaaca atttaacaac aaatgcctat ttattctgga ttccattgac aactcttatt
     7501 cttgtttccc tacctttata cattgtagga caaaacttag cagatgctag tgatccaagg
     7561 acgcatagat aggagaagtc atgactgaaa aacaagaaat tatattaagt gctaaaaata
     7621 ttgttgtaga gtttgatgtg cgtgatcgtg tactgaccgc tattcgtgat gtttctcttg
     7681 atttgtataa gggagaggta ttggctgttg ttggtgagtc aggctctggc aagtctgttt
     7741 taactaagac atttacagga atgctggagg caaatggacg tgttgcttca gggacgataa
     7801 cctatgcagg tcaagaacta acagagctta aaaatcataa ggactgggaa gctattcgcg
     7861 gctctaaaat tgccactatc tttcaggacc caatgactag tctagatccg attcaaacga
     7921 ttggcagcca gattactgag gttattgtta agcatcagaa aaaatctaga tcagaggcta
     7981 aggctttagc aatcgactat atgacaaggg tcggtattcc tgagccagaa aagcgttttg
     8041 gagagtatcc tttccaatat tctggcggta tgagacagcg tattgttatt gccattgccc
     8101 tagcttgtaa gccagatatt ctgatctgtg atgagccgac aacagctctt gacgttacca
     8161 tccaggctca gattattgac ctattaaaga cgcttcaaaa agagtatcac ttcaccatta
     8221 tctttatcac gcatgaccta ggagtggttg caagtattgc tgataaggtt gctgttatgt
     8281 acgcagggga gattattgaa tacggaaagg ttgaggaaat cttctatgat cctcgtcacc
     8341 cctacacatg gagcttatta tctagcctac cgcaattggc agatgaaaag ggcgttctgt
     8401 tttcaattcc aggggcacct ccgtccctat acaagccaat tgttggtgat gcctttgcgc
     8461 cacgctctca gtatgctatg gccattgatt ttgaagaaac agttcctcgt tttacgatca
     8521 gtgacacgca ctgggcaaaa acctggctcc tacacccaga tgctcctaag gttcaaaaac
     8581 cagctgttat tcaggattta caccaaaaaa tattgaaaaa aatgtcacgc caggaggaag
     8641 gaaatgtctg aaaaattagt tgaagtaaaa gacctggaga tttcctttgg agagggaaag
     8701 aaaaagtttg ttgccgttaa aaatgccaat ttctttatca ataaaggaga aaccttttct
     8761 cttgttggag aatcaggcag tggaaagaca acaatcggtc gtgccatcat tggtttaaat
     8821 gagacaagtt caggcgaaat ccgctatgat ggtaagatta ttaatggtaa aaaatcaaaa
     8881 tctgaagcta atgaactgat tagaaaaatc caaatgattt ttcaggatcc agcagccagc
     8941 ctgaatgagc gtgcaacggt tgattatatc atctcagaag gcctttataa ttttaaccta
     9001 ttcaagacag aagatgaacg taaagaaaaa attaaacaga tgatgtcaga ggtgggcttg
     9061 cttgcagagc acctgacacg ctaccctcat gagttttcag gtgggcagcg tcagcgtata
     9121 ggcattgcaa gagcgcttgt aatggatccg gagtttgtta ttgctgatga gccgatttca
     9181 gctcttgatg tatctgttcg tgcccaagtc ttgaatctgt tgaagaaaat acagtctgaa
     9241 aaaggcttga cctatttatt cattgctcat gatttatcgg ttgtgcgttt tatttcagat
     9301 cgtattgctg ttattcacaa aggagtaatt gttgaagtcg ccgaaacaga agagcttttt
     9361 gttaaccctg ttcaccctta taccaaatct ctgctgtcag cagtaccaat tccagatccc
     9421 attttagagc gtcaaaagaa attggtggtt tatcatccag agcagcatga ctattctgtt
     9481 gacaagccat caatggtgga aatcaaacca aatcacttcg tctgggctaa ccaggtggaa
     9541 gcggagcgtt accgcaaaga gctttaagat tagttatcat cacataacag aatttagcct
     9601 cagctagatt ctgtttttgc cttccttggg tagtcttttt tgttctgaca aggatagaaa
     9661 tatccagcat tttccatcta tttacaaaaa acctgtcaaa acc
//
LOCUS       DARYXS010000075         9430 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.076, whole genome shotgun sequence.
ACCESSION   DARYXS010000075 DARYXS010000000
VERSION     DARYXS010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9430
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.076"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(201..989)
                     /locus_tag="TV193_001506"
     CDS             complement(201..989)
                     /locus_tag="TV193_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513687.1"
                     /translation="MSRYSDYKYANTILKSIEERPEKYLIIHYSCESFYNLGGKSPRI
                     ASISVRQFNNAQTNNFSIHQYSEILDTPITDDTYETIEKELLTDFFTFVDRNTDKNWI
                     HWNMRDTVFGFHAIEQRFKVLGGTPIIIDDDKKIDLAYLFKKMYGGGYIDNPHIEKLL
                     ELNNLTPHRFLTGKQEADAFSSRQYHELSMSTSSKVNSFSTFLTLAINDDLKTNTPKW
                     KMRGTNLSGLLSTFQETISGKVIIGIINLIVGGIVGAIIAKYIQ"
     gene            1040..1231
                     /locus_tag="TV193_001507"
     CDS             1040..1231
                     /locus_tag="TV193_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1513688.1"
                     /translation="MPDIAVGREKVVTFLKSNNIKKSDLAAAYGLNRQEVTNILSGST
                     RGPKANQFILRVIADYSIE"
     gene            1312..1623
                     /locus_tag="TV193_001508"
     CDS             1312..1623
                     /locus_tag="TV193_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEL1513689.1"
                     /translation="MPKAELVYRPAKQSEKAEAGDYEHLCQIWEGLTVGTAKVWAAEM
                     RDHPDFKQFINNPTHRIVFIDYEGFRLFVKWKSRNRYKPKKETLAEMLENIKFEKRVG
                     A"
     gene            1625..1795
                     /locus_tag="TV193_001509"
     CDS             1625..1795
                     /locus_tag="TV193_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513690.1"
                     /translation="MNKLELFLLVTTVALAIVARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKKWSAERYV"
     gene            1788..1991
                     /locus_tag="TV193_001510"
     CDS             1788..1991
                     /locus_tag="TV193_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513691.1"
                     /translation="MSKWELQKQLLENATDFESTVEALLDLNESGEISDLELLLNLKD
                     KFRSYSKEKIRILNEILKLGGAE"
     gene            1988..2374
                     /locus_tag="TV193_001511"
     CDS             1988..2374
                     /locus_tag="TV193_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513692.1"
                     /translation="MMTTFEKIIKKINRIEGELVKPEAERRDSLPILSAQLGSIKQDL
                     KLMLWIELLTLNDVERYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDKR
                     NFVKLAEKEFKGATLSWQEFLWGKKK"
     gene            2518..2721
                     /locus_tag="TV193_001512"
     CDS             2518..2721
                     /locus_tag="TV193_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513693.1"
                     /translation="MNYLEYALVYLERELEIIDNEVIEVELPGGDWEFVPNPYYEKGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            2809..3108
                     /locus_tag="TV193_001513"
     CDS             2809..3108
                     /locus_tag="TV193_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513694.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            3108..4265
                     /locus_tag="TV193_001514"
     CDS             3108..4265
                     /locus_tag="TV193_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEL1513695.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKAFKENSDFYNEEMEEMTELYTDIVMEHLNAYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGTLEKLIGKTTFADLLAEVIDKPQGKPVLVKNSDKRPALNSLEQAIKDFE"
     gene            4274..4837
                     /locus_tag="TV193_001515"
     CDS             4274..4837
                     /locus_tag="TV193_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEL1513696.1"
                     /translation="MIMTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHVFMS
                     VSSKTKPQIIDKYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            4880..6802
                     /locus_tag="TV193_001516"
                     /pseudo
     CDS             4880..6802
                     /locus_tag="TV193_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
     gene            6807..9191
                     /locus_tag="TV193_001517"
     CDS             6807..9191
                     /locus_tag="TV193_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1513697.1"
                     /translation="MKQEKLIVKSSPLQELHIATGNSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWRDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGTTPDRYTYTEGS
                     TANGLVIYDEVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDITPTNKLPSSK
                     AMNAFVSDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETVVAIKAQA
                     FSSEVFTESDLNKIVLANGVYDLRDNSFKTKFDPELHARSSHPVVYDPEAACETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYAIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRKALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLAKNAFNHRLRELSYENKNVKSGGKQAKNWVGFKLKSEF"
BASE COUNT         3092 a         1658 c         2183 g         2497 t
ORIGIN      
        1 aaaaatgaaa aaaaacatcg ttgatctaca aaagcgtaaa gagcattttc agtgggtcgc
       61 tgatagctta gaggggaaag aaaacgaact ttacgtggaa agagattggt acgacaatcc
      121 gactcttatt tccaaagagg atgcaaaaaa agaagtagag caaatacgac aagaacttat
      181 tctacttcaa aataaatcat ttattgaata tattttgcaa ttattgcacc aactattcca
      241 ccgacaataa ggttgattat accgattatc acttttcctg agattgtttc ttgaaaagtg
      301 gaaagtaatc cagataggtt agttcctctc attttccatt taggggtgtt agtttttaaa
      361 tcatcgttga tagctaaagt gaggaatgtt gaaaagctat tgaccttgct tgatgttgac
      421 atacttagtt catggtattg tctcgaagag aaagcgtcag cttcttgttt acctgtcaga
      481 aaacgatgtg gggttagatt gttcaattca agtaattttt caatatgcgg attgtcaata
      541 tatcctccac cgtacatctt tttaaacaga taggctaaat cgatcttttt gtcatcatca
      601 atgattattg gtgtgccgcc tagaactttg aatcgctgct caatagcatg aaagccaaag
      661 acagtatctc tcatattcca gtgaatccaa tttttgtcgg tatttctgtc aacaaatgtg
      721 aagaaatctg ttaacagctc tttttcgata gtttcataag tatcatcagt aattggggta
      781 tctaatatct cggagtactg atgaatggaa aagttgttgg tttgggcatt attgaattga
      841 cgaactgaaa tggaagctat tctaggactt ttaccaccta gattataaaa actttcgcag
      901 gagtaatgga taatcagata tttttctggt cgttcttcaa tacttttaag gatagtatta
      961 gcgtatttat aatcagagta tcgagacatt tttacctcaa gtttttattt ttattatatc
     1021 agaaaagaaa ggagaaaata tgccagatat tgcagttgga cgagaaaaag ttgttacctt
     1081 cctaaaaagt aacaatatca agaagagtga tttagcagca gcctatggtc tcaatcgtca
     1141 agaggtcact aacattctta gtggctcaac tagaggacca aaggctaacc agtttattct
     1201 gcgagtgatt gcagattaca gcattgagta aatgcaaaaa aaaggaactg attgcagtca
     1261 gccccttatc aaaaattcta cttacattat atcacagatt ggaggtaaga aatgccaaaa
     1321 gctgaattag tttacagacc agctaagcaa tctgaaaaag cagaagctgg tgactatgaa
     1381 cacctttgcc aaatctggga aggtttaaca gtcggaacgg ccaaggtttg ggcggcagaa
     1441 atgagagatc acccagattt taaacaattt atcaataatc caacgcatag aattgtattc
     1501 attgattacg aaggtttccg tttatttgtt aaatggaaaa gtcgtaaccg ctataaaccc
     1561 aagaaggaaa ccctggcaga aatgcttgaa aatattaaat tcgaaaaaag agtaggagca
     1621 taacatgaac aaattagaat tatttttatt agtaacaact gttgctttag caattgttgc
     1681 caggatacaa tatgaagtca tcaaaaaaca caactcgcca gagaataagc gaaaaatttt
     1741 tagggaagta gctttagaaa acagcaagaa atggagtgca gaacgttatg tctaaatggg
     1801 aattacaaaa acaactactg gaaaatgcga cagattttga gagcacagtt gaggctttac
     1861 ttgacttaaa cgagtctggc gaaatatctg atctggaact cttactgaac ttaaaggata
     1921 aattcagaag ctattccaaa gaaaaaatac gtatccttaa tgaaattctc aagctaggag
     1981 gtgcagaatg atgacaactt ttgaaaagat tattaagaaa attaatcgga ttgaggggga
     2041 gttagttaaa cctgaagctg aaagacgaga tagcttacct atcctatctg ctcagttggg
     2101 ttctattaaa caagatttaa aattgatgct ttggattgag ctactgacgt taaatgacgt
     2161 agagagatat gaagctcttt atcaaggaaa tgattttaaa ttcagtgaaa ctttcttaga
     2221 gcgtcaagcg acgagaaaag ccttttggag acgattagct aaagaaactt tcaaagaaga
     2281 ccaggataag aggaactttg ttaagttggc tgagaaagaa tttaaaggtg caactttgtc
     2341 atggcaagaa tttttgtggg gtaaaaagaa atgaatatat cactaaaatt tattgatgaa
     2401 accctagctg gcttaaatga tattttacgt cagggggggc tcttgctccc aaaaccaagc
     2461 cttagcagac gcagttttta tactaacagc tttaaaacaa gtaattgagg agagaaaatg
     2521 aactatttag aatacgcact agtttatctt gaacgtgagt tagaaattat tgataacgaa
     2581 gttatcgaag ttgagttgcc gggcggagat tgggagtttg tgcctaatcc ctactacgag
     2641 aaaggtctac atgatagccc acactatcgt agtcaggttg ctaaagacat tcttgatatt
     2701 aaaggacttt tggggaggtg aggctattga ttgcatcaaa aaagacggct taggaaaccg
     2761 tcaacaatta tacacaatta aattataaca cagaaagaga gaaacacaat gattgaagta
     2821 acttttaaag cagagagcat ggcaggtgtt ttcgatgcta tgcgtgaagc tctggatatg
     2881 ccgaagacag taaccaagga tgttgttgaa gaaaaaccag ctcctaaaaa gaaagaagag
     2941 tctgtaactt tgacattagc tgatattaag aaaatggcta aagccaaggt tgaagaaggg
     3001 aagtcaaagg acatcaagga agtcttgaaa gagatgaacg tcgcaaaagt tggtgaactt
     3061 gaagaatacc agtttgctga gtttgttgag aagttggagg ccctctaatg ccagtagaaa
     3121 atcacgcact actgtctgct tctagtgctc acagatggct ttattgccct atgctgccga
     3181 gattagaagc agactatcct agccgcgata ccgtatacac tcaagagggc acaagcgccc
     3241 atgagctttc tgaaatcaaa ctgatgtaca agtctggtaa aatcaccaag cgtaaattta
     3301 acacgttaac caaggctttt aaggaaaact cagacttcta caacgaagag atggaagaga
     3361 tgacggaact ttacacagat attgttatgg agcacctaaa tgcttatgag aacgccgaaa
     3421 ttgaacttga aaaacgggtt gattttagcg actgggtgcc tggcggtttt gggacttcgg
     3481 atgttgtcat tttagcggat ggggtcattg aaattattga tcttaagtat ggcaagggca
     3541 tgcctgtgtc tgctaaccaa aacccacaga tggggctgta cgctctagga gcttatgctt
     3601 cctacgatat ggtttatgac tttgaccgta tcaaaatgac cattattcag ccacgtttag
     3661 attcggttag ttctgttgac atttacgtgg aggagttact ctactgggcg gataatgttg
     3721 tcttgcctat ggccgctcaa gcagacgcag gcattggtga ctggaaccta agtgaaaaag
     3781 tattgcagtg gtctcctgtc gcagctaaat tggtaccaag agcgcaagaa aattgggaat
     3841 taattgataa atatgactat caggagcctg tctatttatc tgatgaagcc gtcgcagaga
     3901 ttcttgacaa agcctcagct atcaagaagt gggttgagtc agttgaagcc tatgccctga
     3961 aagaagcact ctcgggaaaa gaagttccag gctataagat tgttgaaggt agaagtaatc
     4021 gagtcatcac tgataaagac aaagcaattg atattttaca agataacggc tttgacgatg
     4081 agatttttaa accgaaagag ctgttagcaa tgggaactct tgaaaagtta ataggtaaaa
     4141 ccacttttgc tgatttatta gcagaagtaa ttgataaacc acagggcaaa cctgtccttg
     4201 ttaaaaatag cgacaagcga cccgcattaa atagcttaga acaagcaatt aaagattttg
     4261 aataggagaa attataatta tgacaccaaa cacaactaaa gtagtaaccg gaaaagtacg
     4321 cctaagctat gtagctttac tagagcctaa agcctttgaa ggtcaagagg ctaagtattc
     4381 aacagttatc ttaattccaa aaacagacaa agtcacaatc aagaaaatta aagacgcgca
     4441 gaaagctgct tatgaggctg ccaaggacaa taaactcaaa ggggttaaat gggagcgcgt
     4501 taagacaacg cttcgtgacg gcgacgaaga aatggatacc gaagagcacc cagagtacgc
     4561 tggacacgtg ttcatgtcag tgtcaagtaa aactaagcca caaatcattg acaagtataa
     4621 aaaccccgtt gactcagcgg atgaagttta ctctggcgtc tatgctcgcg tatcacttaa
     4681 tgcctatgct tacaacacag cgggaaataa aggaatctct tgcggattaa acaacgtcca
     4741 aattgttgct aaaggagact accttggcgg ccgttcgtca gctgatgcag attttgacga
     4801 gtggaacgaa gaagaggacg aagacgacat tttatagtag agggcctctt tagaggctcc
     4861 tcatttttaa aggagaggta tgagacattt aaatattgat attgaaacct atagttcgaa
     4921 tgacatcaaa aatggggttt acaagtacgc tgacgcagaa gattttgaga ttttactttt
     4981 cgcttactct atagatggcg gagaagtaga gtgccttgat ttgacaaggc agtctctacc
     5041 tgaagacatc aaagatatgt tatttgatga taaagtccga aagcacgcct ttaatgccca
     5101 attcgaaaga gtttgtctca gtcgttacct cggtctacct tactatctag atccttgcca
     5161 atggcaatgc accatggtgc tggcccaaga gttggggctg ccttcaagct tggaaaagtg
     5221 tgcgctgtat ttaaaattag tgcaggaaaa agatacctcg ggtaaaaact taatcagata
     5281 cttttccctg ccttgcaaac caagtaaagc taacggtggg agaactagaa atttaccaga
     5341 acacgccccc gaaaagtggt aaatgtttat tgactactgc atccaagacg ttgttgttga
     5401 gatggcaatt gccgaaaaac tagagtcagt tcctgtgcac gaccgtgaat gggactacta
     5461 cgcatgcgac cagagaatca acgacagagg cgtggcgctt gataaagagt tagttgcttc
     5521 ggccttgtat tgcaaagatg ttaagatgga aagtttgtct ggtgaactaa aagctctaac
     5581 aggacttgat aatcctaata gcagggcgca gttgttaccg tggctaaaag aacacggtta
     5641 ttcggttaat ggtctgacta aagcggatgt tgagcaggag cttaagacgg ccgaaggaga
     5701 acttaagaga gttttagaac ttaaactaca aaccgctatg tcaagtctaa aaaaatatga
     5761 agctatggaa agagctatgt gctcagacgg acgagttcat ggactacttc agttttacgg
     5821 agctagcagg acaggaagat gggcgggcag agttgtccaa gtacagaact tagctaggaa
     5881 ttatataaag gatctagatg atgctagaga gtatgttaaa aagcgtgata ttgatgctgt
     5941 ggagatttta tacgatagtc ttaacgacac tttaaagcag ctagtaagaa cggcactcgt
     6001 ggccaaagac tgctgtacct tctacgtctc tgacttctca gcgattgagg ctagggtgat
     6061 tgcgtggttt gccggagagc agtggaggct tgacgtgttt tcgacgcacg gaaaaatcta
     6121 tgaggcatcc gctagccaga tgttcggaat tccaattgag gagattgata aggaactacg
     6181 ccaaaaaggc aaaatctcag agttggcact tggctatcaa ggaggtcctg gagcgctcaa
     6241 gcagatggga gctctaaata tgggagtcaa ggaagaggag ctccaagggc tagttgatga
     6301 ctggcgcagg gccaataaga aaatcgtcca attttggaaa gatgtgcaga gagccgccat
     6361 caaagctatc aaatcgagag caccaataaa acttggaaaa ctacgattta gataccgtaa
     6421 aggtttcctc tttataacat tgcctagcgg taggaactta gcttatgcaa gagccaaggt
     6481 tgagccaggc gactatggag acaaaatcgt ctatgagggc caaggagata aggcctactt
     6541 cacagcgcaa gagacttacg gcggtaagct tgtcgaaaat atcgttcagg cgacggccag
     6601 ggatattcta gctgaagcgc ttctgaggat tgaagctgca ggctatggtg ttgttttcca
     6661 cgttcatgat gaggctatta tcgaaggctc aggcctgaca atcgaagaag ttaatgattt
     6721 gatggctcag gctcctgaat gggcggaggg tcttccttta aatagcgaag gctacgtaac
     6781 aaagtattat atgaaggatt agatagatga agcaagaaaa actaatagta aagtcttctc
     6841 ctctgcaaga gcttcatatc gcaacgggta attcacgaac agctaagacg tggaaaaata
     6901 ttacgctaac ttggcaggag ctggttgaga ggttagagaa acctacagtc acccaagaga
     6961 cgtttgcgga gtaccagaag atgtctcgag cagaaaaagg gcaagcaaaa gacgtaggag
     7021 gttttgtcgg cgggtggcta aagcagggta aacggaaaaa cgaaaatgtt caaagtaggt
     7081 ccttggttgc gcttgacgca gatagcccaa gtaaagattt cttagatagg ctagacctgc
     7141 ttgcagacta tgcatacgta ctctacagta ctcacagcca ctcaaaaaaa gctgctaagt
     7201 accgtcttat tatccctact gaccgtttaa tgatgcctga tgaatatgag ccagtcgcta
     7261 ggtacttggc taatcaacta ggcatgtcga actttgatga cacgacttat caaagtgtgc
     7321 gtttgatgtt ctggccgagc cactcgagag atgctgactt tacgtttaaa tataacgatg
     7381 aggcttttct aagtgttgat gaggtgcttg atacataccc ggactggcgt gactcaagct
     7441 tctggccaga aagcccgacg cacgctgtta aaagacagcg tgaagctaaa aaacaaggtg
     7501 acccacttag taaaaaaggg cttattggag ccttttgtcg taactatgac attagacagg
     7561 ccattgcaac gttcttgccc gaggtttatg aagaaggaac gactcctgat aggtacacct
     7621 acactgaggg ttcaaccgca aatggcttag tcatctatga tgaagtcttc gcttatagcc
     7681 atcacgggac agatcccgtg ggggatacgc ttgtaaatgc atacgacctt gttcgtatcc
     7741 ataaattcgg agagcaagat agcgaggcta aagatattac tcctactaat aagttgccat
     7801 caagtaaagc gatgaatgct tttgtctctg acttacccga aattaaagac tatttaatgg
     7861 cggaggcttt aggcgatttt gatgaagagt taccagtcga agatgacaga agctggcttg
     7921 aaattgatga gaggggcgaa cctgaggtca atagttattt gctagcaacg cagattatta
     7981 aggaggttcc gatttattgg gacggcttag aatttttacg ctacgacgct aaaaaaggca
     8041 tctggttgcc aaacgcagag gagtatttga agagttatat ctcaactaag aaactcggta
     8101 aaattactaa gattaggcac attagcgaaa ccgtcgtagc gattaaggca caggctttct
     8161 caagcgaagt gtttactgag agcgatctta acaagatagt gctagcgaac ggagtctatg
     8221 acttgaggga taacagtttt aagactaagt ttgatccaga attgcatgca aggtcaagcc
     8281 atcccgttgt ctatgacccc gaggcggcct gtgaaacctt tgagggtttt cttagggaga
     8341 ccgtcggagc tgaaaatata gatttcatct ttgagtggtt cggctataac ttttatcgcg
     8401 aatatgctat ccaaaaaatg ctattcatct acggcagcgg cggtactggt aaatcaacac
     8461 tgattaatat tttacgtgaa atgataggtg ctgataatta ctcagccgtg acactgcagt
     8521 acctgatgca agaacgcttt gcaaaaatcg gcttatatcg aaagactgct aacttcgata
     8581 ccgatgctaa acctcaatac ttagcagatg gcgcaacact taaaatgttg acgggggagg
     8641 atactattca cgcagaccgt aagaataaag agccgattaa cttttacaat tatgctaagc
     8701 tgtcttttgc catgaatgag ctcccaccta tgcgagattt cagcggagga cttaaacgcc
     8761 gcatgatgat cctcgagatg gataaggttt taacgcagga agttaaggcg aaatacccgc
     8821 tagataagat tatgagcgag gtgccaggta tctttaatag ggcgatggag gggcttagaa
     8881 aggccttaag taagagagat ttcagtatta gtgccagcat gagatcaagt gtcgagaaat
     8941 gggaaaaagg caacgatgtc gtggccatgt tccttgaaga cgagtgtgaa cttggtgaag
     9001 acttcaaagt tcctgttagg gatgtctacc cagcctacaa gttctattgt caggattcag
     9061 gctacaaacc tttggcaaaa aatgcattta accaccgact aagagagtta agttatgaaa
     9121 ataaaaacgt taaatctgga ggaaagcaag ccaaaaattg ggtcggtttt aagttaaaaa
     9181 gtgagtttta ggggttactt ttttgggatt agagtttggt aaccctagaa aaaagttacc
     9241 aagttaccgg tttttcaaac tttaaaaata aaaaatttaa aaataatttt taaaaaatca
     9301 aaactgaatt ggaaaaatcg gtaacttagt aactcgaccc ttagaaatgg gctcgaaaag
     9361 tagccctggt agcttattgg tagccctaag aaacctttca tagcaatagc ttagccccta
     9421 tggttaccaa
//
LOCUS       DARYXS010000076         9372 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.077, whole genome shotgun sequence.
ACCESSION   DARYXS010000076 DARYXS010000000
VERSION     DARYXS010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9372
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.077"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            62..298
                     /locus_tag="TV193_001518"
     CDS             62..298
                     /locus_tag="TV193_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEL1513698.1"
                     /translation="MEVIRTLLMFFSHLLFIGISYQLLISLVDWSKFIHYRPENMGRL
                     RLLVLFLAIASGYLVSRFMLELIQISQYLLYDFH"
     gene            362..1633
                     /gene="murA"
                     /locus_tag="TV193_001519"
     CDS             362..1633
                     /gene="murA"
                     /locus_tag="TV193_001519"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1513699.1"
                     /translation="MDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLR
                     NVPILSDVFTMNYVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKAERLKGAMI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLT
                     ITGVTSLCGVEHDVVQDRIEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VVEEDAGIRVQADVTKLRPVTVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFEN
                     RFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTT
                     VNKLNHLDRGYYQFHEKLAKLGANIQRISEE"
     gene            1637..1825
                     /locus_tag="TV193_001520"
     CDS             1637..1825
                     /locus_tag="TV193_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1513700.1"
                     /translation="MTNGWRYVINQLMLIIAIGLLGLFCLALGLMIGYSLIGDGQNPL
                     AILSPDKWAELIHKFTGK"
     gene            1857..2735
                     /locus_tag="TV193_001521"
     CDS             1857..2735
                     /locus_tag="TV193_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1513701.1"
                     /translation="MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQR
                     ILGSDTQQAGLPKASRDWDTPSKALADSVMTATIKQQLGDVITWNGTGAYIINHNKTT
                     LNAKVASLPYANNKTKMVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
                     VQGLKGRYSHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQN
                     YYETKIRKALDSNKRVRYRVTLLYEGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGL
                     QIDYQTGQITVASSQP"
     gene            2749..2907
                     /locus_tag="TV193_001522"
     CDS             2749..2907
                     /locus_tag="TV193_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513702.1"
                     /translation="MAKADHVASHHGREALVLVVPQRKVLTIFGLVALVEKQIGPLVE
                     APSMPAPD"
     gene            3647..4690
                     /gene="pheS"
                     /locus_tag="TV193_001523"
     CDS             3647..4690
                     /gene="pheS"
                     /locus_tag="TV193_001523"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEL1513703.1"
                     /translation="MDLQAQLEELKTKTQEALKQLNGDHSKELQELRVAVLGKKGTLT
                     ELLKGLKDLSNDLRPVVGKQVNELRDFLTQAFEEQAKVVEAAKIQAKLDSESIDVTLP
                     GRQMKQGYRHVLTQISEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEDILLRTHTSPVQARTLDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKSISMGDLKGTLEMIIKKMFGKERKIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVNAQEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDSRFSKQFK"
     gene            4880..7285
                     /locus_tag="TV193_001524"
     CDS             4880..7285
                     /locus_tag="TV193_001524"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEL1513704.1"
                     /translation="MLVSYKWLKKLVDIDVSPAELAEKMSTTGIEVEGITSPSEGLSK
                     LVVGHIVSCDAVPETHLHLCQVNTGDDELRQIVCGAPNVKAGINVIVALPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLPDAIIPKDFSEGIQILPETAAAGDSIFPYLDLDD
                     NIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKPLIESAKAAADSLEVAIDSDK
                     VLTYASRIVETVTVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDT
                     FADHKLLARDAREGERLVTLDGEERVLTTDDIVITVADQPVALAGIMGGKSTEITASS
                     KTVVLEAAVFNGKSIRKTSSRLSLRSESSSRFEKGINHDTLVEALDFAAAMLEELAGG
                     TVLAGRLQAGSLPTNPVEVSTSLDYVNVRLGTALSFTDIEGIFARLGFGISGTAEHFT
                     VSVPRRRWDITIPADLVEEIARIYGYDRLPTTLPEAAGTAAELTKTQALRRQLRGLAE
                     GLGLTEIISYALTTPEKALEFAMKPSQLTELMWPMSVERSVLRQSMVSGMLDTLAYNV
                     ARQQHNLAVYEIGKVFEQEGNPKETLPTELNHFAFAITGLVADKDFQTQAQAVDFYHT
                     KGILECLFDKLGLSVDYIPTKEMASMHPGRTARIQLGDQVIGFVGQVHPQAAKAYHIP
                     ETYVAELDLTAIEAALPAHHAFVEITKYPAMVRDIALLVDASTSHQAILSAITSAKVK
                     RLTEIKLFDIYAGAIIAAGKKSMAYSLTFQNPTDNLTDEEVAGYMEKITKALVEKVGA
                     EVR"
     gene            7520..8596
                     /locus_tag="TV193_001525"
     CDS             7520..8596
                     /locus_tag="TV193_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513705.1"
                     /translation="MFLALNEIKQAKLRYGLIMGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDSWQADTVLLSKDADANLSLSSLKTSQLKEIKADEVTPLAQLNTVAWSTQAPTEE
                     DKEKISFFGIERESFLKPTITKGRLFKSDKEVVIDQSLAEKGGFKLGDQLRVSASNQT
                     YTIVGYTKNASFNVSPVAYLNLTAFQGLLYGQEAGAQDPNVNAFIIKGKLADYPKEEL
                     QQLTIGDFINKLPGYSAQLLTFGFMIGFLVLISAIIIGIFMYVLTIQKAPIFGIMKAQ
                     GIANRTIANAVLSQTFVLSLLGSSLGLLGTWLSSLVLPATVPFQSNWYLYALILVAMV
                     VFAVLGTLFSVFTIVRIDPLEAIG"
     gene            8606..9310
                     /locus_tag="TV193_001526"
     CDS             8606..9310
                     /locus_tag="TV193_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513706.1"
                     /translation="MTVLAFKQVTKSFKDGDQTIEALKKTDFAIKAGEFVALIGPSGS
                     GKSTFLTIAGGLQTPSSGQFLVNGKDYTNLSEKERSKLRFKDIGFILQASNLIPFLTV
                     KQQLELVDKLTKHKQEAKRQQLFEDLGIAKLANKLPQDLSGGERQRVAIARALYHDPV
                     IILADEPTASLDTEKAFEVVELLAKESKEKNKAIIMVTHDNRMIDYCDKVYRMQDGQL
                     SQDNHHIASNAAMTQN"
BASE COUNT         2654 a         1968 c         2221 g         2529 t
ORIGIN      
        1 taattattcg tccaactttt tgggggcagt acatttgtta gacttttgat ataataaagc
       61 tatggaagta attagaactc ttttaatgtt tttcagccat ttattattta ttggcattag
      121 ttatcagcta ctcattagcc tagttgattg gtcaaaattc attcattacc gaccagagaa
      181 tatgggaagg cttcgcttgc ttgtcctttt tttggcaatt gcctcaggct atttagttag
      241 tcgctttatg ctggaattaa ttcaaatcag tcagtatctg ctgtatgatt tccactagag
      301 taggcagtca ggaagtatga tataatatta gtacgatgac cagtaggaaa tggagaagct
      361 tgtggataaa ataatcatag aaggtgggag cacacgttta gagggagagg taacgatcga
      421 aggcgctaaa aatgccgttc ttcctttact agcagctact atcctcccct caactggaaa
      481 gactgtcttg agaaatgtgc cgattctctc agatgttttt acgatgaact atgttgtgcg
      541 tggcctaaat attgacgtcg actttgatga ggctgccaac cagattacag ttgatgcctc
      601 aggggacatt ttagatgttg ccccgtacga gtatgtcagc caaatgcgcg cctcaattgt
      661 ggttttaggc ccgattttag ctcgtaatgg ccatgccaag gtatcgatgc ctggaggctg
      721 tacgattggc agtaggccga tcgatttgca tttaaagggc ctagaggcta tgggcgctga
      781 gatcacccag cagggtggtg acatcactgc aaaggctgag cgcctaaagg gggcaatgat
      841 ctatatggat ttcccatcag tgggggctac gcaaaatttg atgatggcag cgacccttgc
      901 tgatggtgtg acagtcattg agaatgctgc tcgcgagcct gagattgttg acctagccca
      961 gctgctcaac aaaatggggg ctaaggttcg tggggcaggt accgaaaccc tgaccataac
     1021 gggtgtcacc agtctatgtg gggttgagca tgatgttgtt caggatcgta tcgaagcagg
     1081 tacctttatg attgctgcag caatgacctc cggtaatgtg ctgattagag atgctgtatg
     1141 ggagcataat cggcccttga tttctaagct catggaaatg ggagtgtctg ttgtcgaaga
     1201 ggatgcaggc attagggtgc aggctgatgt gactaaacta aggcctgtca ctgttaaaac
     1261 tcttcctcac ccaggctttc caacagatat gcaggctcag tttacagccc ttatggccat
     1321 tgttaaggga gaatctacga tggtggaaac agtctttgaa aatcgtttcc agcacctaga
     1381 agaaatgcga cgcatgggct tacaatctga ggtattgcgt gatacagcta tgattcatgg
     1441 tggtcacgaa ttacagggag cgcctgtgat gtcaacagac ctgcgagcta gtgcagccct
     1501 catcttaacg ggaatggttg ccaaaggcag gaccactgtg aataaattga accatttaga
     1561 tcgtggctat tatcagtttc atgaaaagct tgccaagcta ggtgccaaca ttcagcgaat
     1621 tagtgaggag tagtcaatga ctaatggttg gagatatgtc ataaatcagc taatgctaat
     1681 catagctatt ggactgctcg gactcttttg tctggcgctg ggactaatga ttggctatag
     1741 ccttatcggt gatggccaaa atcctttagc gattttatcg ccagataagt gggctgagct
     1801 gattcataaa tttacgggaa agtaggcatg gcctgctttt tatgataaga ggaaagatga
     1861 tcaaaaagaa gaaagacatc aggctgctta atgccttttt agcgctcttg cttgttcttg
     1921 gaacaggtta tttggcagga catgatgacc tagcagctga taacccgatc aagcaggtct
     1981 accaaaggat tcttggctct gacacgcagc aagccgggct accaaaggca agccgagact
     2041 gggacactcc ctccaaggcc ttggcagatt cggtcatgac agccaccatc aaacagcaat
     2101 taggtgatgt gattacttgg aatggcactg gtgcctatat cattaaccat aataaaacga
     2161 cgctaaatgc aaaggtagct agtctcccct atgccaataa taaaacaaag atggtacaag
     2221 ggcaaagcgt tcctaccgta gccaatgccc tgctaaccaa gtcaacccga caatatcaga
     2281 agcgcaatga cactggaaat ggctatagct catggaagcc tgctggctgg catcaggttc
     2341 aggggttaaa gggaaggtat agtcacgcag tggatagagg gcatcttcta ggctatgcgc
     2401 ttgttggcgg gctaaaaggc tttgatgcct caatggctaa tcctagtaat atcgctactc
     2461 aaaccgcatg ggctaaccaa gcagctaacg agagatcaac cggacaaaac tattatgaaa
     2521 caaaaattcg caaagcccta gatagcaata agcgtgtccg ctatcgtgta actttgcttt
     2581 atgagggaaa taatctctta gcaagcggca gtcatcttga ggcaaagtca tcagatggta
     2641 gcttagaatt taacgtcttt atccctaatg tacaggctgg attacagatt gattatcaaa
     2701 caggtcagat cactgtagct tcttcccagc cttagtgagg cacatcacat ggcaaaagct
     2761 gatcacgtag ctagccatca tggcagagaa gcattagtcc ttgtagtccc tcaaagaaag
     2821 gtgctaacaa tatttggtct tgtggcttta gtagaaaaac agataggtcc tttagtcgaa
     2881 gcaccaagca tgccagctcc tgattaggac aaatgtcaag gctaagcggt ggtaagttaa
     2941 agtctcacaa aagacaagac tggacttttg gctatagtcc tttatgactg atgccagctg
     3001 ataatggctc aagatgattg aggtttctag caatgcttgt ggctagccta tcgtcttagt
     3061 tagcgctgat tgatgagatg ttgaacagtt cttgactaaa agcatcccta cccttacgcc
     3121 tacgtcctgg ttagtgaaga aataagcatt gtcataaagg catttttttg atacaataaa
     3181 agtaattgaa tagcagtcta tgagactagt actaataggg aagttaatag ggaatggggg
     3241 tcgtgactgg aagccttctt aatgaaacga ttaggaattc actcaatcaa ggacgaggta
     3301 attaaggtct gacttgctca gatgaaaacg gatggtaccg cgtgtcaacg ctccgcttta
     3361 gataggagcc ttgatacgcc ttttttgatg acgtgctgtt actattagct atttaatcac
     3421 aagcaagcac tagccagcca aaagtaagtg atcactataa gcatagaaag ataggagctg
     3481 tagcttatct agaaaagcaa gggtgatcag tcgtccgccc aaaagtcttt cttagctttt
     3541 gtgatgtgac tagctgacct agctgctcac agcttagcct aaaaggccta ttagcacaag
     3601 gactgccagc attaatgcaa tcattttcca aacagaaggg aatatcatgg atttacaagc
     3661 acaattagaa gaactgaaaa ccaagacaca agaagcgctc aagcagctaa atggtgacca
     3721 cagcaaggaa ttacaggagc tgcgggttgc tgtccttggg aaaaaaggaa cgcttaccga
     3781 actgctcaag ggactaaagg atctctcaaa tgacctgcgt cctgttgttg gcaaacaggt
     3841 caatgagctt cgtgactttt tgacccaagc ctttgaagag caggctaagg tggttgaggc
     3901 agcaaagatt caggccaagc tagattctga aagcattgat gtgactttgc caggccgtca
     3961 gatgaagcag ggctatcgac atgtgctcac tcaaatcagt gaagaaattg aggacatttt
     4021 cttgggcatg ggctttcaaa ttgttgatgg ctttgaggtt gaaaaggatt attataattt
     4081 tgaacgcatg aaccttccaa aggatcatcc ggctcgtgat atgcaagaca ccttctatat
     4141 cacagaggat attttgctgc gcacccacac cagtcctgta caggcacgaa cactggacca
     4201 gcatgatttt tcaaaggggc ctctcaagat gatttcacct ggacgtgttt tccgtcgtga
     4261 caccgatgat gccactcatt ctcatcaatt tcaccaaatt gaaggcttag tcgttggtaa
     4321 gtctatttct atgggagact tgaaggggac tcttgagatg atcattaaaa agatgtttgg
     4381 taaggagcgt aagattcgcc tgcgcccatc ctatttccct tttactgagc catctgttga
     4441 ggttgatgtc tcatgcttca aatgtggtgg taaaggctgc aatgtctgca aaaaaacagg
     4501 ctggattgaa attcttggag ctggtatggt gcacccaagc gttttagaaa tgtcaggtgt
     4561 gaatgcgcag gagtattcag gctttgcctt tgggcttggt caagagcgca tcgccatgct
     4621 gcgctatggt atcaacgata ttcgaggctt ctaccaagga gatagtcgct tttctaagca
     4681 gtttaagtaa tagtgatcat atggtcaaaa accaaatcat cagtttgaaa aaagaactga
     4741 cgctcaatct ggagctgttc tttggattag aatcagaaag gaaaaagacg ggtaaagagc
     4801 aaagaagtga ttggctagct tatctcaagc aggtgctagg cagatctctc atcagcgctc
     4861 actactctat tgaaggctta tgttagtatc ttataaatgg ttgaaaaaat tagttgacat
     4921 tgatgtctca ccggccgagc tagctgaaaa aatgtcaaca acaggtatcg aagtagaagg
     4981 catcaccagc ccctctgaag gtttatcaaa gctagttgtt gggcatattg tctcatgtga
     5041 cgctgttcca gaaacgcacc tgcacctttg tcaggtcaac acaggagatg atgagcttcg
     5101 tcaaattgtc tgcggtgcac ctaatgtcaa agcagggatt aatgtgattg ttgcgctgcc
     5161 tggagctcgt attgcagaca attacaagat taaaaagggt aaaatacgcg gtatggagtc
     5221 tcttggcatg atctgctcac ttcaggagct tggcttacca gatgcgatta ttccaaaaga
     5281 tttttcagaa ggtatccaga tcctaccgga aacagcagca gcaggtgata gcattttccc
     5341 ttaccttgat ttagatgaca atatcattga gctttccatc acacctaatc gtgctgatgc
     5401 cttatcaatg cgtggtgttg cccatgaggt ggcagctatc tatggcaagt cagtgtcatt
     5461 tccagaaaag ccccttatcg aatccgctaa agcagcagct gatagtctag aggttgctat
     5521 tgactctgac aaggtgctga cctatgctag tcgtattgtt gaaactgtca ccgtcaagcc
     5581 aagtccgcaa tggctgcaaa atcttctgat gaacgctggc attcgtccaa tcaacaatgt
     5641 tgttgatgtg accaattatg tcttgctgta ttttggtcag ccaatgcatg cctttgatta
     5701 tgataccttt gctgatcata agcttttagc gcgtgatgcg cgtgagggag aaaggcttgt
     5761 cacccttgat ggagaagagc gtgtgctaac cacagatgac attgttatta ccgtagcaga
     5821 ccagccagtg gctctagctg gtattatggg aggcaaatca acagaaatca ccgcctcctc
     5881 aaagacagtg gtgcttgaag cagcagtctt taatggcaaa tcaatccgta aaacaagcag
     5941 tcggctaagt cttcgttcag aaagctcatc acgctttgaa aaagggatta accatgacac
     6001 gcttgtagag gccttagatt ttgcggcagc catgctagaa gagctagccg gtgggactgt
     6061 tttagcaggg cgcttgcagg caggctcact gcctaccaat ccggtagagg tttcaaccag
     6121 ccttgattac gtcaatgtcc gcttgggaac agccttgagc tttactgata ttgaggggat
     6181 ttttgcaagg cttggctttg gtattagcgg aactgctgaa cactttaccg tttcagtgcc
     6241 acgacgccgg tgggatataa caattccggc tgacctagtc gaagaaattg cccgtatcta
     6301 tggctatgat cgattgccaa ccacattacc agaagctgct ggcacagccg cagaattaac
     6361 caaaacacag gcccttcgtc gtcagctgcg tggtcttgca gagggactgg gtttaacaga
     6421 aatcatttcc tatgctctaa caacacctga aaaggccctt gaatttgcaa tgaagccaag
     6481 ccagttaaca gagctgatgt ggccaatgtc agtcgagcgc tctgtccttc gtcaaagcat
     6541 ggtatcaggt atgcttgaca cccttgccta caatgtggca cgtcaacagc ataaccttgc
     6601 cgtttatgag attggtaagg tctttgagca agagggcaat cccaaggaga cattaccaac
     6661 agagcttaat cactttgcct ttgctatcac aggcttagta gcagacaagg attttcagac
     6721 acaagcgcaa gcggttgatt tttaccatac taagggaatc ctagagtgtc tctttgataa
     6781 gctaggactg tctgtggatt atatcccaac aaaggagatg gcgagcatgc acccaggacg
     6841 taccgcacgt attcagctag gagatcaagt gattggcttt gttggtcagg tgcacccaca
     6901 ggctgctaag gcttatcata tcccagagac ctatgttgca gagcttgacc tgactgctat
     6961 agaggcagct ctaccagctc atcatgcctt tgtggaaatc accaaatacc cagctatggt
     7021 aagggatatt gccttattgg ttgatgcctc aaccagtcat caagccattc tttcagcgat
     7081 cacgtctgcc aaggtaaagc gtctaacaga gattaagctc tttgacattt acgcaggagc
     7141 aattattgcg gccggtaaaa aatcaatggc ctatagcctg accttccaaa atccaacaga
     7201 caatctgact gatgaggagg ttgccggcta catggagaaa atcaccaagg ccttggtaga
     7261 aaaggttggt gcagaggtga gataaggacg cttctaatga ctagctacct aaaaaaagct
     7321 catttcaaag gcttagctgc aattgttctg ttgcggctga gctttttttg atgcttagac
     7381 tgtccttatc ctatgctagt tgcagcaagg gtttagagat gattttattt aaattatcag
     7441 tcaaaaatat tttttctaat caaattccta gctttatctg atctcctctg ctatactgtg
     7501 caataagtaa ggagattata tgtttttagc cctaaatgaa ataaaacaag ctaagctcag
     7561 atatggcttg attatgggac tgctctgttt agtagcctat ttgatgttct ttttatccgg
     7621 tttagccttt ggattaatgc aggaaaatcg ctcggcagtt gacagctggc aggcagatac
     7681 agttcttttg tcaaaggacg ctgacgccaa tctcagccta tcctctttaa agaccagtca
     7741 gcttaaggag atcaaggctg atgaggtcac tcccctagcc cagctgaata cagttgcttg
     7801 gtcaacccaa gctccaacag aagaagacaa agaaaaaatc agcttttttg gcattgagag
     7861 agagtccttt ctcaagccta caatcacaaa aggaaggcta tttaagtcag acaaagaggt
     7921 ggtgattgat caaagccttg ctgagaaagg aggctttaag cttggagatc agctgcgggt
     7981 atcggcctct aaccagacct ataccatcgt tggctatacc aagaatgcta gctttaacgt
     8041 gtcacctgtt gcttacctca acctgacagc ctttcagggc ttactgtatg gtcaagaagc
     8101 aggcgcacaa gacccaaatg ttaatgcctt tattatcaaa ggcaagctag ctgactatcc
     8161 caaggaagag cttcagcagc taacgattgg cgacttcatc aacaagctgc cgggctatag
     8221 tgcacagctc ttgacctttg gctttatgat tgggttttta gtgttaatct cagccattat
     8281 cattggtatt tttatgtatg tgctgaccat tcaaaaggca ccaatctttg gtatcatgaa
     8341 ggcacaaggc attgctaatc gtaccattgc aaatgctgtg ctatcacaaa cctttgtcct
     8401 aagccttttg ggcagcagcc ttggcctact aggcacctgg ctaagctcgc ttgtcttacc
     8461 agcaacagtt ccctttcaga gcaattggta cctatatgcg cttattttag ttgctatggt
     8521 agtctttgca gtattaggca ccctcttttc agtctttacg attgttagaa ttgaccctct
     8581 agaggccatt ggttaggaga agaatatgac agtattagca tttaagcagg tcacaaagtc
     8641 ctttaaggac ggtgatcaga ccattgaagc cctgaaaaag acggattttg cgattaaagc
     8701 aggcgagttt gtcgccctta taggtccatc aggctcaggc aaatcaacct ttctgaccat
     8761 tgcaggtggt ctacaaacac caagctcagg acaattttta gtcaatggca aggattacac
     8821 caacctatct gaaaaggaac gatcaaaact acgctttaag gacattggct ttatcctgca
     8881 ggcttctaat ttgattccat ttttaaccgt caaacagcag ctagaattag ttgacaagtt
     8941 gaccaagcac aagcaggaag caaagcgtca gcagctcttt gaggacttgg gaatcgctaa
     9001 gctggctaat aagctgcccc aagatttatc cggtggcgag cgtcagcgtg ttgccattgc
     9061 cagagcccta taccatgatc ctgtgatcat tttagcagat gagccgactg ccagtctgga
     9121 tactgaaaag gcctttgagg tcgttgaact tctagctaaa gaaagcaagg aaaaaaacaa
     9181 ggcaattatc atggtaaccc atgataaccg tatgattgac tattgcgata aggtctatcg
     9241 catgcaggac ggccaattga gtcaagacaa tcatcatata gctagcaatg ccgcaatgac
     9301 tcaaaactaa tcgaatagga aaagctctgc tctagcgata tagcagggct ttttagctgc
     9361 tctaaattat ct
//
LOCUS       DARYXS010000077         9170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.078, whole genome shotgun sequence.
ACCESSION   DARYXS010000077 DARYXS010000000
VERSION     DARYXS010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.078"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            101..1027
                     /locus_tag="TV193_001527"
     CDS             101..1027
                     /locus_tag="TV193_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1513707.1"
                     /translation="MEKIIITATAESIDQVKSLLAAGVDRIYVGEADYGLRLPHAFSY
                     DDLRQIAALVHKAGKELTVACNALMHQGMMDRIKPFLDLMKEIAVDYLVVGDAGVFYV
                     NKRDGYDFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSEELFALADNLDYPAE
                     ILVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDPDSHYSIYEDNHGTH
                     IFINNDIDMMTKLGELYEHGLTHWKLDGVYCPGENFVAITKLFIKAKALLESGQFTTE
                     LAQQLDAEVQGLHPVGRGLDTGFYDFDPKTVK"
     gene            1135..2421
                     /locus_tag="TV193_001528"
     CDS             1135..2421
                     /locus_tag="TV193_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1513708.1"
                     /translation="MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHKYGAKVYVAANMVTHEGNELGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVNMAELAEIRKRT
                     EVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGSERRSL
                     KGEIPEEYSMSSVDMCMLEHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKDDLIDELWKVAQRELATGFYYHIPTENEQLFGARRKIPQYKFVGEVV
                     SFDDDSMTATIRQRNVIVEGDRVEFYGPGFRHFETVIKDLHDADGNKIDRAPNPMELL
                     TISLPQAVKPGDMIRACKEGLVNLYQKDGTSKTIRA"
     gene            complement(2517..2842)
                     /locus_tag="TV193_001529"
                     /pseudo
     CDS             complement(2517..2842)
                     /locus_tag="TV193_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2977..3189
                     /locus_tag="TV193_001530"
     CDS             2977..3189
                     /locus_tag="TV193_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEL1513709.1"
                     /translation="MSEFTFKIEEHLLTLSESDKGWTKELNRVSFNGAEPKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRR"
     gene            complement(4085..4225)
                     /locus_tag="TV193_001531"
     CDS             complement(4085..4225)
                     /locus_tag="TV193_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513710.1"
                     /translation="MKKEYISYLSAAIFILYALLSLKWIFFVLGVILLIIGLADRFRS
                     KP"
     gene            complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TV193_001532"
     CDS             complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TV193_001532"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEL1513711.1"
                     /translation="MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGEL
                     KEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGFAHLQDRQGQIQIYVRKDSVGDD
                     NYDIFKKADLGDFIGVEGDIMCTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRSSFERFITRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQDIDMVLRIAPELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYE
                     AYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRRVHMVDAIKEVTGID
                     FWPEMTFEEATALANEKHVPVEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVS
                     PLAKKNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            6424..7901
                     /locus_tag="TV193_001533"
                     /pseudo
     CDS             6424..7901
                     /locus_tag="TV193_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
     gene            8213..9118
                     /locus_tag="TV193_001534"
     CDS             8213..9118
                     /locus_tag="TV193_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1513712.1"
                     /translation="MISAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSLINRAYIRFR
                     HYSDVGFPRVMSGEWTTEYFRFWRCRETLLEFGYRDIDQATGVHFQEVYEHELQHITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLRKVRKLGLYDYVDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPATTLYVGDSYDNDVMGAKNGGWHAMWFNHRGRSLKPGTRPIY
                     DVAIDNFEQLFGAVKVLFDLPDNKVIFDINDKKNPVLQLGLNNGLMMAAERLLESNMS
                     IDKVVILLRLNKQQERVLRMKYANR"
BASE COUNT         2533 a         1730 c         2097 g         2810 t
ORIGIN      
        1 ttttttttga aggcttctcg ttataggcct tggtataggc gttaagattt tgaatgaatc
       61 atttttgaaa gcctaagaaa tttggtataa tatcccttgt atggaaaaaa taattattac
      121 agccacagca gaaagcattg accaagtcaa atcgctttta gctgcaggtg ttgatcgtat
      181 ttatgtaggc gaagctgatt atggcttgcg tcttcctcat gctttttctt atgatgactt
      241 gaggcagatt gcagcgcttg ttcacaaggc gggcaaggag ctaacagttg cttgtaacgc
      301 tctgatgcat cagggcatga tggatcgtat aaagcccttt ttggacctta tgaaggagat
      361 tgctgtcgat taccttgttg ttggtgatgc cggtgttttt tatgtgaata aacgagatgg
      421 ctacgacttt aagctgattt atgatacttc ggtttttgtt acctcaagcc gtcaggttaa
      481 tttttggggg cagcatggcg ctgttgaaag tgttttagct agagagattc cctcggagga
      541 attatttgcc ttggctgaca atcttgacta cccagcagaa atattggttt acggggcctc
      601 tgttattcat cattctaaga gaccgctcct tgaaaattat tatcatttta ccaaaattga
      661 tgacgaggtc agtcgagagc gtgggctttt cttagcagag ccaggcgatc ctgatagtca
      721 ttattctatc tatgaggaca atcatggaac tcatattttt attaacaatg acattgatat
      781 gatgactaag ctaggcgagc tatatgagca tggcctgaca cattggaagc tagatggtgt
      841 ttactgtcct ggtgagaatt ttgtggccat taccaagctg tttataaaag caaaggcttt
      901 gctggagtct gggcaattta ccacagagct agctcagcag cttgatgcag aagtgcaagg
      961 gcttcaccct gtagggcgtg gtctggatac aggcttttat gattttgatc ctaaaacagt
     1021 caaataagct ataacttgac ttgtcctgat taaggttact atttcaaggc atgacaagtt
     1081 aatcattcaa agatgttaca tcttacctat cttgaaaata gaaagaataa caacatgtca
     1141 aatgtaaaaa aacgtcctga ggtgctgtcg cccgcaggaa cacttgaaaa attaaaggtt
     1201 gccattgatt atggcgctga tgcggttttt gttggtggac aggcctacgg gctaagaagt
     1261 cgcgcaggaa acttctctat ggaggaatta caagagggga ttgactatgc tcacaagtat
     1321 ggggctaagg tctatgttgc tgccaatatg gttacccatg agggcaacga gcttggggct
     1381 ggtgagtggt tccgtcaatt gcgtgatatg gggcttgatg cggtcatcgt ttcagacccg
     1441 gcccttattg tgatctgctc aacagaagca ccaggacttg agattcatct atcaactcaa
     1501 gcatcatcaa cgaactatga aacctttgaa ttttggaagg aattaggcct aacgcgtgtc
     1561 gtgctagcac gtgaggtcaa tatggcagaa ttggctgaga ttcgaaagcg cacagaggtt
     1621 gagattgagg cctttgtaca tggtgccatg tgtatttcct attcagggcg ctgtgttctc
     1681 tctaatcaca tgagtcaccg agatgccaat cgcggaggct gctcacaatc ctgccgctgg
     1741 aagtatgatt tgtatgatat gccttttggc tcagagcgtc gttccttaaa aggagagatt
     1801 ccagaggaat actccatgtc ctcggttgac atgtgcatgc tggagcatat ccctgatttg
     1861 attgaaaatg gagttgatag cttgaaaatc gaagggcgca tgaagtctat ccattatgtg
     1921 tcaacagtga ccaattgcta taaagcagct gttgatgctt atatggaaag tccagaggca
     1981 ttttatgcta ttaaggacga ccttattgat gagctttgga aagtggctca gcgtgagcta
     2041 gcaactggct tttactacca tattccaact gagaatgaac agcttttcgg tgcgcggcgt
     2101 aagattccgc aatacaaatt tgttggggag gtggtttcct ttgatgatga cagcatgaca
     2161 gccactattc gccaacgtaa cgtcattgtt gaaggagaca gggttgagtt ttacggaccg
     2221 ggcttccgtc attttgaaac agtgatcaag gatttacatg acgctgacgg caataaaatt
     2281 gaccgtgcgc caaacccaat ggagctctta accatctcct tgccacaggc tgtcaagcca
     2341 ggagatatga ttagggcctg taaagaagga cttgttaacc tctatcaaaa ggacggaacc
     2401 agtaagacca taagagccta gcaccactag actaagcaat aggatttgac caattacttt
     2461 tgacacagag aagtgataag gttaggtctc ctttactcct gattagggta ctgagtctat
     2521 ggcttttctt tggtgctggt gcgtgtatga ggtactaagc tagccttatc aatatctgct
     2581 aaaaaaataa tgcagtcagg ttttgattgg tattttttaa gaccaattga ccggttagct
     2641 gatcgtattt tttaatgtgc ccagtgaagc ttttggcttg atagatcaca tgaattggaa
     2701 tctccttgac ctgtgcctct ttgatggtgg taatgatctg gttggccttg aggttaacgg
     2761 gagaagcctt ggcttttttg ggaggctgat tgtcaataaa gccgatcaag gctgattgca
     2821 gctgcttcat cattgatttc atagctattg tcctcaaaca ttgatagaat agtttgatag
     2881 tattttacct taaactatga tttttaaaaa gaatttactg ttttgcattc aatttttaat
     2941 attattttcg aatagataga tgaggaggaa aatataatgt cagaatttac atttaagatt
     3001 gaggagcatt tgctaaccct gtcagaaagc gataaggggt ggacaaaaga gctaaaccgc
     3061 gttagcttca atggagcaga gccaaaatgg gatatccgca cctggagccc tgatcacaca
     3121 aagatgggta agggcattac tctgaccaat gaagaattta agacaattct tgatgccttt
     3181 cgtcgttaag ccttagctta gtcatcaata acttcaatgt gagaagaacc ttttctaacg
     3241 aacagtatca accatcagtt actttgttct tgtaggaagg ttcttttgtt atctcttcaa
     3301 gtgagttttt aagagcaagg taaaagacta tcgtctagaa cccccttagc attcatagct
     3361 gctaccgcaa cgataaaagt taaaaaacaa actaactggg gatctggtat ctagaaagtt
     3421 aatctagtcc tcttagagct tttagtaact gttagtcact atttattggt gagaggaata
     3481 tatcacaatg ctccaatcga gccttggttt gggtgtttta agtccggatg ctatgagcta
     3541 aagtcatacc agacttgtga agagcctatc actgatagta atcgctatct ctacttttac
     3601 aatgatagtc atctttaaaa gcacatgaaa ggccctgccc ctcctttaag gaggaacaag
     3661 gcttctgttt aatcattatg agattagtat tcgcttaata ggaagtcact caagctcagc
     3721 gtctattttg agactgatgc ttctgtccta gccttaggct gctcatattc tgctctaaaa
     3781 tcatacggat tgtcctgatt tgctttagaa tagcatactt gttgagtcta ggtcccaagg
     3841 atcttgaatg actgacgttg aaggtgttta gctcctgtta tcttggtata agaaggtatg
     3901 accttttggt aattggattg tctattgtat ggttccaaga tgatgattgg catgcttggt
     3961 tgttgactgc aagctgatag ccttgtggga ggctttgctt tcataaggct taagggctat
     4021 ttttacttta atgtaaggct ccttggctgg cagctatcga gacttggaga tgatagaggg
     4081 ctagctaagg ctttgacctg aaacgatcgg ctagaccaat aatcaagagg atcaccccta
     4141 aaacaaagaa aatccatttc aagctgagta aggcataaag gataaaaata gcagctgaga
     4201 ggtaactaat gtattctttt ttcataagat gctccctatc tttttatact attgtagcat
     4261 aaaaatcagt ttaaatgctg atgaaatcaa tggctatttt ggctttcatt ggcctagtaa
     4321 aaaccgttta gcctagcagc atgtcatcat tgcaaacaaa aaagattgaa gaatcaagtc
     4381 taagagatga ttcttcaatc ctagtataca gacaagctaa ggacatcact tcaaaagtga
     4441 ggcttttaga gaagctaaag gcaactaatg actattagct aggcctagct atggaagtga
     4501 ttggtcatag tgatcattcg atctggataa gaggcttagg atcagctaga gaaagctgct
     4561 ttttaaacac tggtagctag tcgcttttta tggcttcatt gttgggaata acaaaacatc
     4621 gcgaatagtg gttgtatttg tcagcagcat gcagaggcgg tcaataccga ttccaagccc
     4681 gcctgttggt ggcataccgt attcaagagc ctcaacgaag tcgtagtcaa taccggttgc
     4741 ttcatcgtct ccaagctcct tggctgctgc ctgtgcctta aagcgtgaca gctgatcaat
     4801 tggatcattt agctcggtaa aggcattagc atattccttt gtcatgataa agagctcaaa
     4861 gcggtctgtg aagcgactgt cctcagggtt tttcttagca agcggtgaaa cctctacagg
     4921 gtgcccatag acaaaggttg gctgaattag ggtgtcctcg acaaatgcct caaagaaggc
     4981 attgatgata tgaccaacag aggtaaaatg cttttcaact ggcacatgct tttcgttagc
     5041 aagagctgtt gcttcctcaa aagtcatctc aggccagaag tcaataccag ttacctcctt
     5101 gatggcatca accatatgca cgcgtctgaa tggttcatga agcttgattt cagtcccctg
     5161 ataatcaatt ggtccctctc ccttgactgc tttagcagcg tgctgaatga ttccttcagt
     5221 tagagtcatc atatctaaat agtctgcata ggcttcatag acctcaatag aggtaaattc
     5281 tgggttatgt gtagcgtcca tcccttcatt acgaaagatc cgtccaattt catagacacg
     5341 ctccatgcca ccgacgatga ggcgcttgag atgcagctct ggtgcaatgc gaagcaccat
     5401 atcgatatct tgtgcattgt ggtgagtgat aaagggacga gcagcagcac caccagcttc
     5461 attatgaagg acaggtgtct ccacttctaa aaagccaagg ccatcgaggt aacgacgaat
     5521 ttcagaaatc atttttgaac gtgtgatgaa ccgttcaaag ctgctgcggt ttgaaatcaa
     5581 atccagatga cgcttgcgat aaatggtttc gatatcagtt aagccatgaa atttctctgg
     5641 tagcggacgt agagatttgg atagatgggt cagttttgtg gccttgatag acaactcacc
     5701 catatcagta cacataatgt cgccttcgac cccgataaaa tcaccaaggt cagctttttt
     5761 gaaaatgtca tagttgtcat caccaactga atccttacga acatagattt ggatttgccc
     5821 ttggcgatcc tgaagatgag caaagccgac ctttccttta ccacgcttgg tcatcagacg
     5881 accagcaata atcgcagtgg cttgaagctc ttgtaaatcc tctttggttt tgtctgagta
     5941 tttttccttt aattcaccag aattagttgt tcggtcgaag cgtttgccaa atggatcaat
     6001 gccttgctca gctaaggctg ccattttttc acgacggaca atttgttgat catttaattc
     6061 ttcgatgtgt tgatttgaca tgttttcctc caatactttt ccttcctatt gtaacataaa
     6121 agattataga atacacctat atttcgtggg aattctatca tcgaagcctc agatgatagg
     6181 cctttgactt gtatagataa attggttttg tctgagttgg tttttctgta taaataagct
     6241 attatttgtg agatcttact tgaattgaag gcttttgcta gttccaatag attatttttg
     6301 atgatatttg acaaaaaaac ttaaattgtg aaaaaatatt aatcgaaaaa atcaaaaaac
     6361 tctcaacgct aaggctagtc tttgtgcagt tgagggtttt tatcaggaaa ggatcataaa
     6421 gaaatggaaa cttatgatat acacgggaag ccttatcatc gaacgctgat gattatattg
     6481 ctgttggtgg gaacctttgc aggggtttta aaccaaacaa gcttggggac agctatacca
     6541 acattgatgg aaaattttaa ggtacctttg tcaacaactc agcaggcaac cacttggttt
     6601 ttgcttgcta atggcattat gatccctgtt tcggcctttt tagcaacgcg attttccact
     6661 aaaagactct acatgacagc ttatgctatt cttgtgagtg gcttgttact agcagctctg
     6721 gctccgactg ctcattgggg agttttttaa cagcacgtat cgttcaggct tgtgcagtgg
     6781 gcattaccat gcctttgatg caggtggtga tgatcaacgt ttttcctgca gagcagcgtg
     6841 gtgcagcaat gggaatcaat ggcttggtgg ttgggctagc tccggctgtt ggaccaacct
     6901 tgtcaggctg gattttgaaa aaggattttt cagtattagg catttattta ggctggcggg
     6961 ccatttttat cttgccttta gtgattttgc tgttggtttt aagcctgtcg cccttcatgc
     7021 tccgagatgt tatccctcag caggctgtta agcttgattc aacatctcta ggcttatcta
     7081 tcttagggct gggtgctttt ctctggggct ttacaaatgt tgcagcttat ggctggctag
     7141 atatggtgta cgtgatttta cctattttag tcggtattgg tggaatttac ctcttttcca
     7201 agcgtcagct acaattagag aagccctttt tagatattag agtctttcgc aacaagcaat
     7261 ttaccttgac aacaatagca attgccctaa cgatgatggc tatgatcggt gttgagatga
     7321 tgctgccgct gtatctgcaa aatgtcagag gcttatctcc attaaattcc ggaatggttt
     7381 tgttgccggg tgctttgatt atggggctga tcagtccagt ttctggccga atttatgaca
     7441 agatcggtgc tcgttatctg gcgctattag gctttaccat tttagctgcg gcgactctac
     7501 catttgtatt tctaaatgaa aatacctcac gctttttgat tactgttttg tatgccatta
     7561 gaatgtttgg catatcaatg attttaatgc ctttaactgc aagtgctatg aatgccttgc
     7621 catcgcatga atcggcgcat ggaacggcag ctaataatac tgtacgccag atctcctctt
     7681 ctattgttgt ggcggtgtta tcgagtgtga cacaaaacat tatcagcagc aaacagccgc
     7741 ctaaaatgct cctatccata caccctgagc aatacgctaa gaagcttcta gaagccaatt
     7801 taaatggctt tcatgcctct tttttccttg gctttatgtt tgcagtggta ggctttattg
     7861 ttgtgctttt cctacataag ggaaaggtta tcgagaaata gctcctgatt agtgtggtta
     7921 aaacaaatag gctaaaggcc tcacgccaaa cgcatgaaaa aacagctgtt tttgatagct
     7981 tttctgatta atgcactctt tttcaagaaa acttatggca caatgaagct aaatgtgagc
     8041 agttgatgat gtcaaaataa tggaaaatct attgaaaaat gtttgagtct agaaaattgt
     8101 tacctgcatt ttctttgtgt ctctagcatg ctaaaagcat gggctggttt gaaaagtcga
     8161 tgacaaaata gtataatgat aagcatatca acctagaaaa gaaaagagac tcatgatttc
     8221 tgcaattgtt tttgatgtag atgatacgat ttatgaccag caggcgcctt accgtatcgc
     8281 aatggaaaag tgctttccag attttgatat gtcattgatc aatcgagcct atattcgttt
     8341 tcgccattat tctgacgttg gatttccaag agtgatgtca ggtgagtgga cgacagaata
     8401 ttttcgattt tggcggtgtc gggagaccct gcttgagttt ggctatcgtg acattgatca
     8461 ggcgacagga gtgcattttc aagaggtcta tgagcatgag ctgcagcata ttaccatgct
     8521 tgatgagatg cgcatgacac ttgatttctt gaagtcaaaa aacgttccga tggggattat
     8581 cacaaatgga cctactgagc accagctaag gaaggtgcgt aagctagggc tatacgatta
     8641 tgttgatcct aagcgcgtga ttgtcagtca ggcgacaggc tttcaaaagc cagaaaaaga
     8701 gatattcaac ctagcagcag agcagtttga catgaaccct gcaacaaccc tctatgtcgg
     8761 cgactcttat gacaatgatg ttatgggagc taaaaatggt ggctggcatg ccatgtggtt
     8821 taaccacaga gggagaagtc taaagcctgg gacaaggcct atctatgatg tggccattga
     8881 taactttgag cagctgtttg gtgctgttaa ggtcttgttt gatctgccag acaacaaggt
     8941 tatttttgat atcaacgaca agaaaaaccc ggtgctgcaa ttaggactta acaatggttt
     9001 gatgatggca gcagagcgct tgctagaaag taacatgagt attgataagg ttgttatcct
     9061 gttacgcttg aataagcagc aagaaagagt gctgcgcatg aagtacgcta atagatagca
     9121 gttattgatt gaaaagcatg ctatgtttaa ttggcactcc aaaggctaga
//
LOCUS       DARYXS010000078         9030 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.079, whole genome shotgun sequence.
ACCESSION   DARYXS010000078 DARYXS010000000
VERSION     DARYXS010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9030
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.079"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            31..276
                     /locus_tag="TV193_001535"
     CDS             31..276
                     /locus_tag="TV193_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1513713.1"
                     /translation="MGIIWTLIVGALIGAIAGALTKKGGSMGWIANIAAGLIGSYVGQ
                     ALFGSWGLTLAGMALFPSIIGAVIVVIITSFVLNKSN"
     gene            324..905
                     /gene="amaP"
                     /locus_tag="TV193_001536"
     CDS             324..905
                     /gene="amaP"
                     /locus_tag="TV193_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEL1513714.1"
                     /translation="MSKFLKISYSLIGLVLLTVFGGVIAITGDYIRLPIGYQWLHWDM
                     NWLPKFLNPALYYYYFWAAIALFLITVLILLVIIFYPRTYTEIQLAKDKGTLLLKGSA
                     IEGYVAAAIKAAGLMSSPRVTAKLYKRKFKVNVSGQLASRVAVTEQLNGIKEGIETGL
                     TEFFGINRPVHFKVYVKDIADAKQKHSSKRRVE"
     gene            915..1103
                     /locus_tag="TV193_001537"
     CDS             915..1103
                     /locus_tag="TV193_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEL1513715.1"
                     /translation="MAFYERFKYPIIGGLIGLIAAVLLMTFGLFKTLLAIIFIILGVY
                     GGLYAKKTGIIDQLIKRN"
     gene            1116..1655
                     /locus_tag="TV193_001538"
     CDS             1116..1655
                     /locus_tag="TV193_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1513716.1"
                     /translation="MTETYIKNTTHKEPTSAVRGELTYDDKVIEKIVGLALENIDGLL
                     GVNGGFLANLKDKLVNSDSVRDGVNVEVGKKEVAVDLDIVAEYQKHVPTIFDAIKSVV
                     ENEVKRMTDLEVIEVNVKVVDIKTKEQFEADKVSLQDKVTEVARSTSEFTSKQVDNVK
                     ASVGAGVEKVQEQTEPRVK"
     gene            1693..1890
                     /locus_tag="TV193_001539"
     CDS             1693..1890
                     /locus_tag="TV193_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL1513717.1"
                     /translation="MSEEKVNAKLEQAGGKIKEAFGKVTGDKSLETEGKVDQAASKIK
                     EVAADAKDAVKGFVKGLKQDK"
     gene            1900..2388
                     /locus_tag="TV193_001540"
     CDS             1900..2388
                     /locus_tag="TV193_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1513718.1"
                     /translation="MKAKDIKSTLTYDDKVIEKIVGHALEKVSGLLAVNGGFFSNIKN
                     NLVNSDSVRDGVSVEVGSKEVAVDLDIVVEYGKDIPAIVESIKAIVFQNVDSMTHLRV
                     VEVNVNVVDIRTKEEHEAASVTVQDRLTDAASATSQFVAEQADKVKETVSKTTDNNET
                     VE"
     gene            2544..3185
                     /locus_tag="TV193_001541"
     CDS             2544..3185
                     /locus_tag="TV193_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1513719.1"
                     /translation="MTSNKREITNSKYQKIAISVAERIANGEYEVGEKLKSRTTIAST
                     FKVSPETARKGLNILADLKILTLKHGSGAIVLSKEKAIDFLNQYESTHSIAVIKENIR
                     HNIREQEKAMEHLTVLVNEFLMQSQSISKQYPLAPYEIICSQDSEHFGQSIGDLNIWH
                     QTGATIVAIEHDGQFIVSPGPYAVIEKGDHIYFVGNEDVISRMKTFFNVRKGL"
     gene            complement(3302..3850)
                     /locus_tag="TV193_001542"
     CDS             complement(3302..3850)
                     /locus_tag="TV193_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1513720.1"
                     /translation="MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTF
                     YLHYRDKHDMMTHLINDTLDDLYQLLNDPHIFTDTRLVLKEALAYIIDNLPFIAAMAN
                     SSYLNFSQILKDFIYQFLTTIDGFQEIITKHYQIPYHYALEVYLASIESLISYWISHD
                     CQETTDDMTAIILKTVGFEKVI"
     gene            3973..4674
                     /locus_tag="TV193_001543"
     CDS             3973..4674
                     /locus_tag="TV193_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513721.1"
                     /translation="MSYIEMRSSSKTYQIGETTVKANDEVSFEIERGELVIILGASGA
                     GKSTVLNILGGMDSNDQGQVIIDGKDISTYSKKALTSYRRYEVGFVFQFYNLVPNLTA
                     KENVELAADIVADALDPTTVLNEVGLGGRLEHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILRLLQDMAHDKGRTVIVVTHNTALAPIADRVIYMHDGRVTK
                     TVLNKQPLDIDRITY"
     gene            4686..7325
                     /locus_tag="TV193_001544"
     CDS             4686..7325
                     /locus_tag="TV193_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL1513722.1"
                     /translation="MKQKTLWKDSFRAIKASKGRFLSLLFLMALGSFALVGLKVAGPN
                     MEKTASHYLEEHQVMDLSILTSHGFSDRDKQELASLKNARLEYASFVDGAFDHQRKAI
                     RLYSMPQSLSQASLVKGDYPSKASDILLSEALSSRYRLGQIITISLKTKGLLKHRSYR
                     VVGFAHSPEIWSKTNLGVSSAGDGNLYAYAYLHPSAFQQGHNLLRIRYDDLRGLNAFS
                     TQYNERLLQHQAELDQILQDNGQERYEEMLNDLNRSLKDSKVKLEEQRTVLKASEDQL
                     ALLSGHALEQAQTQLKQGQEELAKKEASLLELAEKQRAAMIKPTYTSYSRSTLPGGEG
                     YQTYATSTQSISHVGNIFPVVLYLVAALVTFTTMARYVDEERTNSGLLKAIGYSDWDI
                     TKKFLLYGALAALLGTGLGVLGGTYFLSRLISAILTDALTIGSTQLYFYWSYSVVAVL
                     LALLSAVLTAYMVVRRELFLRPSQLLLPKPPSSGARIWLEHVSFIWRRLSFTYKVTFR
                     NIFRYKQRMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLTAYDMLVVEAPTAE
                     AHDRQELAQYLKADQIASKKEIYYANLSLKIKDLDNKQTVSLISSDQSTLSPYFSLIG
                     AADRKKLDLPSTGVLISKKLADYYQAHAGDQLELEASNGKRYQLRVSQVIDMTVGHYL
                     FMSKSYYQQVFRDMEASPSYLVTTAKASPSAVKDVASQLLAMPAVQAVSQHSSIVATV
                     TGIVASLDQVMTLLVLLSVLLALVILYHLTNINIAERVRELSTIRVLGFYDKEVTLYI
                     YRETMLLSAVGILIGLWGGSYLHAYIMKVIANDSMSFGRTVDAYVYLVPVGAIVLLLI
                     VLGYMVSYRLRKIDMLEALKSVD"
     gene            7401..7997
                     /locus_tag="TV193_001545"
     CDS             7401..7997
                     /locus_tag="TV193_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1513723.1"
                     /translation="MEAMIAAYLADHREKIPLGQVVDCFKGKAVSRKAEAGEFGLINL
                     SDMGQLGIDYHQVRAFHMDRRQLLRYILEDGDVLIASKGTVQKVCVFHKQEREMVASS
                     NITVLRPQRVLRGYYIKFFLESAIGQALLKAADHGKDVINLSTKALLDIPVPVIPLVK
                     QDYLINQYLRGLHDYQRKVNRAEQEWQFIQNEIQKGLG"
     gene            8007..8969
                     /locus_tag="TV193_001546"
     CDS             8007..8969
                     /locus_tag="TV193_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1513724.1"
                     /translation="MSLIERTIKMLLATMAAIFLASQLQLSYAISAGIIALLGVLDTR
                     KSSLIVARKRLLSFFLAFAVAVSLFALFGFGLLSIGLYLALTIPLLYQLKIEAGLVPI
                     TVLVTHLMSEQRIDLSILFNELLLFLIGTGLALLVNGYMGSQEHRLRLYHQKIEDSLK
                     AILYRFESFLLEGQGQNEGQMIKELELSLDEALKLVYRERHNTLFYHTNYQVHYFEMR
                     RHQNRLLAQMALNVTQLTSQSRESLLLSHLFHETARQLSEKNSALTLIDDIEQLLEVF
                     RQRELPQTREEFERRAILFQLLQDLERFILLKVEFYRDYKEEQA"
BASE COUNT         2602 a         1566 c         2122 g         2740 t
ORIGIN      
        1 agtagtttta ttgaattgag gagatttatt atgggaatta tttggacatt aattgtgggt
       61 gcacttatcg gtgctattgc cggtgcgctt actaaaaaag gcggatcaat gggctggatt
      121 gccaatatcg ctgcaggact tattggatca tacgttggtc aagctttgtt tggcagctgg
      181 ggtctaacat tagctggcat ggcacttttc ccatcaatca ttggtgctgt tatcgttgtt
      241 atcattactt cttttgtact aaataaatca aactaagggc atttctatca ttatagagat
      301 ggttgagtag gaaagaggtt tttatgtcga aatttttaaa aattagctat agtctcattg
      361 gcttagtcct attgacggtc tttggtggcg tgatagccat aactggagat tatattaggc
      421 tacctattgg ctatcaatgg cttcactggg atatgaattg gcttcctaaa ttcctaaatc
      481 cggccttata ttactattac ttttgggcag ctatcgcttt atttctaata acagtgctga
      541 tccttcttgt gattatcttt tatccacgca cctatactga gattcagctg gctaaggata
      601 aaggaaccct gcttttgaaa gggtctgcta ttgaaggcta tgtagcagct gctattaaag
      661 cagcagggct tatgtcaagc ccaagagtta ccgctaagct gtacaagcgt aaatttaagg
      721 ttaatgtcag tggacaatta gcttctcgcg tagctgtcac tgagcagcta aatggcatta
      781 aagaaggaat tgagactggt ttaacagaat tctttggtat taatcgacct gtccatttca
      841 aggtttatgt caaggatatt gctgatgcta agcaaaagca tagctctaag agacgtgtag
      901 aataggagat tatcatggca ttttatgaac ggtttaaata ccctattatt ggtggtctga
      961 tagggctgat agctgctgta ttactgatga cctttgggtt atttaaaaca ctgctggcaa
     1021 ttattttcat tattttagga gtatatggcg gcctgtatgc caaaaagaca ggtattatcg
     1081 atcaattgat caaacgtaac taaaggagat ttatcatgac tgaaacttac attaaaaaca
     1141 caactcataa agaaccaact tcagctgttc gtggcgaatt gacctatgat gacaaggtca
     1201 ttgaaaagat cgttggcttg gctcttgaaa acattgatgg cctactaggt gttaatggtg
     1261 gctttttggc caatctaaaa gacaagcttg ttaatagtga ttctgttcgt gatggggtta
     1321 atgttgaggt tggtaaaaaa gaggttgctg ttgatttaga cattgtagca gaataccaaa
     1381 agcatgttcc aaccattttt gatgcgatta aatctgtcgt agaaaatgaa gtcaagagaa
     1441 tgacagattt agaggtgatt gaggttaatg ttaaggttgt tgacattaaa accaaggagc
     1501 aatttgaagc tgataaggtc agcctacagg ataaggtgac tgaggtagct cgctcaacct
     1561 ctgaatttac aagcaagcag gtagacaatg ttaaggcatc tgtaggtgca ggtgtagaaa
     1621 aggttcaaga gcaaactgag ccacgcgtta agtaagctag gctgtcaaac gatagaaata
     1681 gaggaaatca taatgtcaga agaaaaggta aatgcaaaat tggagcaagc aggcggtaaa
     1741 atcaaagaag cctttggaaa ggtgactggt gataaatcct tagaaaccga aggtaaggtt
     1801 gatcaagcag ccagcaaaat caaagaagta gctgctgatg ctaaggacgc tgtcaagggc
     1861 tttgttaagg gccttaagca agataaataa ggagttgtaa tgaaagcaaa ggacataaaa
     1921 agtacgttga cctacgatga taaggtcatt gaaaaaatcg ttggacatgc tttagagaag
     1981 gtcagtggct tattagcagt caatggtggc tttttctcaa atatcaaaaa taacctagtg
     2041 aatagtgact ctgttcgtga tggggtgtct gttgaggttg gcagcaagga agtggctgtt
     2101 gacttagata ttgttgttga atatggtaag gatattccag caattgttga gtctatcaag
     2161 gctattgttt ttcaaaatgt cgatagcatg acacatttga gggtcgttga agtaaatgtg
     2221 aacgttgttg atattagaac caaagaagag catgaggctg ctagcgtcac tgttcaagac
     2281 aggctaacag acgcggcctc agcaacctct caatttgtag ctgagcaagc agacaaggta
     2341 aaagaaactg tctctaaaac cacagataat aacgagacag tagaataaaa cacaacaact
     2401 aaaactcctg ttaatgacat attgtgggct ggtgtgatga ccagctcttt ttatcagtgc
     2461 ttgaacaatg ttatgctatt gtattctctg tgaaaatgtg atttaatggg aatggtatca
     2521 tttgttaaaa aggagtaatt atcatgacta gtaataagag agagattact aattccaagt
     2581 atcaaaagat tgccatttca gttgctgaaa ggattgccaa tggcgaatat gaagtgggag
     2641 aaaagctaaa gtctaggaca accattgctt cgacctttaa agtttcgcct gaaactgcta
     2701 gaaagggtct gaatatttta gctgatctga agattttgac cttaaagcat gggagtggcg
     2761 ccattgtctt gtctaaggaa aaggctattg attttctgaa ccaatacgaa tccacccatt
     2821 ctatcgctgt catcaaagaa aatattcgcc ataatattcg tgagcaggaa aaggcaatgg
     2881 agcatttaac agtgcttgtt aatgagtttc tgatgcaaag ccaatcaatc agcaagcaat
     2941 acccgctggc accttacgaa attatttgta gtcaggattc agagcatttt ggccaatcca
     3001 ttggtgattt gaacatttgg catcaaacgg gagcgacgat tgtagctatt gagcatgatg
     3061 gccaattcat tgtttctccc ggtccttacg ctgttatcga aaaaggtgat catatttact
     3121 ttgtcggtaa tgaggacgtg atttctagaa tgaaaacctt ttttaatgtt agaaagggtc
     3181 tgtaatcaca aaaaaacaca gagctgcttt aaggtgatgg tgatatcacg atgaagtgtc
     3241 tctgtgtttt tgtgttatca ggctaaggct tctaagtagc ttatagctct gattgaagcc
     3301 cctagattac tttttcaaag ccaacagttt tcaggataat agctgtcatg tcatcggttg
     3361 tttcttgaca gtcatgacta atccagtagc taatcagact ttcaatactg gctagataaa
     3421 cctcaagcgc gtagtgataa gggatctgat agtgcttggt gatgatttct tgaaagccat
     3481 caatagtggt caaaaattga taaataaaat ccttgagtat ttgtgaaaaa ttcaaataac
     3541 tggagttagc catagcagca ataaagggaa gattatcaat gatataagcg agggcttcct
     3601 ttagaacgag tctagtatct gtaaaaatat gagggtcatt taggagctgg tataaatcgt
     3661 ctaaggtgtc atttatgaga tgagtcatca tatcatgttt atccctgtaa tgcagataaa
     3721 aggtgcctct attgacacca gcttttttgg ttaagtcaga aacggtaatg gtctcaaagc
     3781 tcttttctgt caaaagactg acaagtgcct gcttcaaata ggccttggtt ggtgtgtgtc
     3841 ttgttgtcat cgactcatct ccttaagtca acaaatgctg cttatctgtt cttgttaaag
     3901 tcttgaggac attatataat aaggctagta taaaatcaac aaggtgttga tataaaggag
     3961 gtgacatgat cagtgtccta tattgaaatg aggtcctctt caaagaccta ccagattgga
     4021 gaaacaactg ttaaggctaa tgatgaggta tcctttgaga ttgaaagagg ggagcttgtg
     4081 atcattttag gagcctctgg tgcaggcaag tccacagtgc ttaatatttt aggcggcatg
     4141 gatagcaatg accaaggtca ggtcataata gacggcaagg acatctcgac ctatagtaaa
     4201 aaggcattga ccagctaccg tcgttacgag gttggctttg tttttcaatt ttacaatctg
     4261 gtgccaaatc tgacagcaaa ggaaaatgtt gagctggcgg ctgatattgt ggcagatgca
     4321 cttgatccga ctactgtctt aaatgaggtg gggctaggag gacgtttgga gcatttccca
     4381 gcacagctat caggaggtga gcagcaaagg gtgtctattg ctcgtgcctt ggctaaaaat
     4441 cctaagttgt tgctttgtga tgagccaaca ggggctttag attatcaaac cggcaagcaa
     4501 attttaagat tgcttcaaga tatggcgcac gacaagggca ggacagttat tgtggtgacg
     4561 cataatactg ctctagcgcc tattgctgat cgggtcattt atatgcatga cggtcgtgtg
     4621 accaagacag tgcttaataa gcagccgctt gatattgata ggataacgta ttgagaggtg
     4681 cctagatgaa acaaaaaacc ttatggaagg atagttttcg agcaataaaa gctagtaagg
     4741 ggcgtttttt gtccttgcta tttttaatgg ctctaggctc ctttgccttg gttggcttaa
     4801 aggtggctgg tcccaatatg gaaaaaactg ctagtcacta tctagaggag catcaggtta
     4861 tggaccttag tatcctaacc tcgcatggct tttctgatag agataagcaa gaattagcct
     4921 ctcttaaaaa tgcaagacta gagtatgcga gctttgttga tggtgctttt gatcaccaga
     4981 ggaaggctat taggctttat tctatgccac aaagcctatc tcaggccagc ttggtcaagg
     5041 gagattaccc tagcaaggct agcgacattt tgctatctga agctttatca agccgctatc
     5101 ggcttgggca aataatcacg ataagcctaa aaacaaaggg attgctaaag catagatcct
     5161 atcgtgttgt cggctttgct cattctccag aaatatggtc caaaacaaac ttaggtgttt
     5221 cctcagcagg ggatggtaat ctctatgcct atgcctacct tcaccctagt gcctttcagc
     5281 aagggcacaa tctcttacgc attcggtatg atgatttaag agggttgaat gccttttcaa
     5341 ctcaatacaa tgaacgattg ctacaacacc aagcagagct tgatcagatc ttgcaggaca
     5401 atggtcaaga gcgttatgaa gaaatgctca atgaccttaa tcgcagcttg aaagatagta
     5461 aagttaagct cgaagagcaa aggactgttc ttaaggcaag tgaagaccag ctggctttgc
     5521 taagtggtca tgccttagag caagcgcaga ctcagctaaa gcaagggcag gaagagttag
     5581 ctaaaaaaga agcaagcttg ctagagttag ctgaaaagca aagggcagcg atgatcaagc
     5641 caacctatac tagctatagt cgctcaacgc tgccaggtgg tgagggttat caaacctatg
     5701 ccacctcaac acagtccata tcgcatgttg gaaatatctt tcctgttgtt ttgtatttgg
     5761 ttgcggcctt agttactttt acaacaatgg ctcgctatgt tgacgaagaa cgaacgaact
     5821 caggcttact aaaggcaata ggctattctg attgggatat taccaaaaaa tttctgctat
     5881 atggtgcctt agctgccttg ttgggcactg gattaggagt tttaggaggg acttattttt
     5941 tatctcggct catctcagct atcctaacag atgcattgac tatcggctct actcagcttt
     6001 atttttattg gagctatagt gtggttgcag tgcttttagc cttgttatct gctgttttga
     6061 cagcttatat ggtggtgaga cgtgagcttt ttctcagacc ctcacaactg ttgctgccta
     6121 agcctcctag tagcggggca aggatttggc tggagcatgt ctcctttatc tggcggcgtt
     6181 tatcctttac ctataaggtt acttttcgaa atatctttcg atataagcaa agaatgctga
     6241 tgacagtaat tggagtagca ggttctgttg cgctcttatt ttccggcttg ggcattcaat
     6301 cctcacttgc taatagccta agctatcaat ttggcaagct gacagcctat gacatgctcg
     6361 tggtagaagc tccaacagca gaagctcatg ataggcagga gctggcacaa tatttgaagg
     6421 cagatcagat tgctagtaag aaagagattt attacgctaa cttatcacta aagataaaag
     6481 acttagacaa caagcaaaca gtgtcgttga tttctagcga tcagagcact ctatctccct
     6541 attttagctt gattggtgct gctgaccgaa aaaagctaga ccttccaagt actggagtgc
     6601 ttatctcaaa aaagcttgct gactattatc aggctcatgc aggagatcag cttgagcttg
     6661 aagctagtaa cggtaaacgc tatcagttaa gagtgagtca ggttattgac atgactgttg
     6721 gtcattactt gttcatgtct aaatcttatt atcagcaggt atttcgggat atggaggctt
     6781 caccatccta tttggtaaca acagcaaagg ctagtccatc tgctgtaaag gacgtagcta
     6841 gtcagctctt agcaatgcct gcggttcagg ctgtgtcaca acacagtagt attgttgcta
     6901 ctgtgacagg gattgtggcg tctttggatc aggttatgac gcttttagta cttctatcag
     6961 ttctactagc cttggtcatt ttgtatcatt tgaccaatat caatattgct gagagggtta
     7021 gggaattatc aacgataaga gtcttgggct tttatgacaa ggaggttacc ttatacattt
     7081 accgggaaac catgcttttg tctgctgttg gtattttgat cggtctctgg ggtggcagct
     7141 atttgcacgc ctatatcatg aaggtgattg ctaatgattc tatgagcttt ggtaggacag
     7201 ttgatgctta tgtttaccta gtacctgttg gggctattgt gcttttgttg attgtgcttg
     7261 gctatatggt tagctaccgg ctaagaaaga ttgatatgct agaggctcta aagtctgttg
     7321 attagggtaa aatagtactt gaaaatcgct taataatatg ctagtattaa aatactataa
     7381 tttaatagaa ggatactttt atggaagcga tgatagctgc ctatttggct gatcatagag
     7441 aaaagatacc acttggtcag gttgttgatt gctttaaggg gaaggctgtt tctcgtaagg
     7501 ctgaggctgg tgaatttggt ttgattaatc tgtctgatat gggacagcta ggaattgact
     7561 atcatcaggt tagagccttt catatggata gacgacaact attgcgctat atcttagagg
     7621 atggagatgt cttgattgcc tcaaagggga ctgttcagaa ggtttgtgtt tttcataagc
     7681 aagaaaggga aatggtagcg tcctctaata tcacagtgct gcgtcctcag agggttttgc
     7741 gaggctatta tattaagttc tttttggagt ctgctattgg tcaagccttg ttaaaggcgg
     7801 cggatcatgg aaaggacgtg attaacctat cgaccaaggc tttacttgat atccctgtac
     7861 cagtgattcc tttggttaag caggattatt tgattaatca atatttgcga ggcctgcatg
     7921 actatcaacg gaaagtaaac agagctgagc aggagtggca gtttattcaa aatgaaattc
     7981 aaaaaggctt gggctagagg taaaatgtga gcttaattga acgaacaata aaaatgctat
     8041 tagcaacgat ggctgcaatc tttcttgcct ctcagctaca gctgtcttat gccatatcag
     8101 cgggaattat tgccctgtta ggtgtgctag acactagaaa atctagctta attgttgcta
     8161 gaaagcgtct gctgtctttt ttcttagcct ttgctgtggc ggttagtcta tttgccttat
     8221 ttggctttgg tctgctttcc attggcttgt atctagcgct aaccattcct ttgctttatc
     8281 agctgaaaat agaggcaggt cttgttccta tcactgtctt ggtgactcac ctgatgtctg
     8341 agcagcgtat tgatttgtca attcttttta atgagctgtt gctgtttttg attgggacgg
     8401 gtcttgccct tcttgttaac gggtatatgg ggtctcagga gcatcgccta cgcttgtacc
     8461 accaaaagat agaagatagc ttaaaggcta tcttgtaccg ttttgaatcc tttttgttag
     8521 aaggccaagg acaaaacgag ggacagatga ttaaggaatt agagcttagc ttagatgagg
     8581 cgctaaagct ggtttatcgc gaaaggcaca ataccctctt ttatcatacc aattatcagg
     8641 tgcattattt tgagatgaga cgtcatcaaa atagattgtt ggcgcaaatg gccttaaatg
     8701 tcactcagct aacatctcaa agcagagaaa gtctcctgct ctcccatctt tttcatgaga
     8761 cagctcgtca gctgagtgag aagaattctg ctttgacatt gattgatgat attgagcaat
     8821 tgcttgaggt ctttaggcaa agagagctgc ctcagactag agaggaattt gaaagacggg
     8881 cgattctgtt tcagctgttg caggatttgg agcgctttat tctactgaag gtagaatttt
     8941 atcgtgatta caaggaagag caggcatagt agctgcttgc tgctgtgatt aagagtctgg
     9001 aaaaatcatt ttctaggctt ttttgctata
//
LOCUS       DARYXS010000079         8727 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.080, whole genome shotgun sequence.
ACCESSION   DARYXS010000079 DARYXS010000000
VERSION     DARYXS010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8727
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.080"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(56..1390)
                     /gene="trmFO"
                     /locus_tag="TV193_001547"
     CDS             complement(56..1390)
                     /gene="trmFO"
                     /locus_tag="TV193_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEL1513725.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHK
                     TTHFAELVCSNSFRGDSLTNAVGLLKEELRRLDSIIMRAGEAHRVPAGGAMAVDREGY
                     AKAVTAELENHPLIEIIREEVIDIPSDAITVIATGPLTSDSLAEKIHALNGGAGFYFY
                     DAAAPIVDKSTINMDRVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNAF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYKGPRDGDFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLEHAEFVRYGVMHRNSYMDSPKLLTQG
                     FQSRANHRLFFAGQMTGVEGYVESAASGLVAGINAARLFKEEEPLVFPNTTAIGSLPY
                     YITHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAKRALADLAAYLTV"
     gene            complement(1772..2485)
                     /locus_tag="TV193_001548"
     CDS             complement(1772..2485)
                     /locus_tag="TV193_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEL1513726.1"
                     /translation="MQGLSDYLYQHPILVLLVICHFLSDYHLQSQVIADKKEEQLAYL
                     GLHLLGVAAPLFLVVMCIPKLWLTAILIFSSHAVIDYFKPKWARIIKLDRSWVFVLDQ
                     LLHLFIILALVARVNQAEIPDWLHARQLLLVLFMVLITKPVNIIFKLCFNKFQPASDK
                     PMDTIVGAGAAIGNLERIVMGVCMVLGQFASIGLVLTAKSIARYNKISESPAFAEYYL
                     IGSLFSVLSVFIAAWMCFF"
     gene            complement(2506..3153)
                     /locus_tag="TV193_001549"
     CDS             complement(2506..3153)
                     /locus_tag="TV193_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1513727.1"
                     /translation="MLYIAVIGDLVHSKQIQSRSLVQESLKACLDQLNHDFSSYIVSN
                     LSVTLGDEFQGLLTNDAPVFQLIDLINQAMTGYPVRFGIGQGTILTDINPDISIGADG
                     PAYWRAREAIHYIHQKNDYGNTQVAIRTDKEHKDLVLNSLLAAGEAIKASWRASQLEV
                     FHALLDLGIYEEQFDQQLIGDTLDLQSSALSKRLKSSSVKVYLRSRHAALTYLQE"
     gene            complement(3268..5400)
                     /gene="topA"
                     /locus_tag="TV193_001550"
     CDS             complement(3268..5400)
                     /gene="topA"
                     /locus_tag="TV193_001550"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEL1513728.1"
                     /translation="MVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKY
                     LGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINALKKEAKNAKKVY
                     LASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQ
                     QARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPEEYWSID
                     GLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSRLSSDDFMVSKVEKKERRRHAPL
                     PYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVA
                     QNDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLK
                     LYTLIWNRFVASQMTAAVFDTVKVNLEQNSVLFVANGSQMKFDGYMAVYNDSDKSKML
                     PEMTEGEVVKKVTLTPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLDVIQRRY
                     YVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQ
                     FYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHH
                     TKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGD
                     YLVEKKIRGGKQVVCSNEVCDYKEEIVK"
     gene            complement(5501..6346)
                     /gene="dprA"
                     /locus_tag="TV193_001551"
     CDS             complement(5501..6346)
                     /gene="dprA"
                     /locus_tag="TV193_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEL1513729.1"
                     /translation="MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCC
                     KNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYPLALREIYNPPVLLFYQGDLSLL
                     EKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
                     AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVL
                     VVEAKQRSGSLITCQLAMEEGRDIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILS
                     EYHYS"
     gene            complement(6592..7374)
                     /locus_tag="TV193_001552"
     CDS             complement(6592..7374)
                     /locus_tag="TV193_001552"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEL1513730.1"
                     /translation="MTAMTIKDIKARLEAVSSLSDPFFEELKADKRLGVQKAVSSRKR
                     ALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPVVAACVILPKGCTI
                     KGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMTAAINQL
                     EGSVSKPDYLLIDAMTLEVSIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAF
                     PGYGFAKNAGYGTKEHLQGLHQYGVTPIHRQSFEPIKSMILR"
     gene            complement(7355..8209)
                     /gene="ylqF"
                     /locus_tag="TV193_001553"
     CDS             complement(7355..8209)
                     /gene="ylqF"
                     /locus_tag="TV193_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEL1513731.1"
                     /translation="MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMLLNKADLADNTHTKKWQQYYEKQGIKTLAINAKEQATVKRVTEAAK
                     ELMADKLRRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIATVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKKYY
                     PNRLLKRFKAIDLEADAPEIIMSLTRQLGFKEDYDRFYSLFIKDIRDGRLGQYTLDQV
                     GDDDSNDY"
BASE COUNT         2566 a         2013 c         1597 g         2551 t
ORIGIN      
        1 gtcctctcca gatgttagct tgtcaactac ccactacagt tgacatggag cctgattata
       61 ccgttaaata agctgccaga tcagctaagg cacgtttagc gatagcttca tagcgttcct
      121 ttttatctct gatacgaggt ccgtcaagct ctttaataat accaaaattg acattcattg
      181 gttgaaaatg cttgctgtcc gcgtgtgtaa tataataagg caggctgcca attgctgttg
      241 tatttggaaa aacaagtggc tcttcttcct tgaatagccg agcagcatta atgccagcca
      301 caagtccaga agctgctgac tcgacatagc cctccacacc ggtcatctga cctgcaaaga
      361 aaagcctgtg attagcgcgt gattggaagc cttgtgtcag aagctttggt gaatccatat
      421 aggaattacg gtgcatcaca ccgtaacgca caaactcagc atgctcaagg cctggaatca
      481 tttggaaaac ccgcttttgc tctccccatt ttaaatgtgt ctgaaagccc acgatattat
      541 aaaggctgcc tgcagcatta tcctgacgca gctgcacaac agcatagggc gtcttgaaat
      601 caccgtcacg tggtcccttg taatcatctg gatattccaa gccaaccggc ttcattggac
      661 cataaagcat agtcttaatc ccacgctttg ccataacctc aattggcata cagccttcaa
      721 aatacttttc cttttcaaaa gcatttaaag gagcttcctc tgctgttgtc aaagcctcgt
      781 gaaaggccat aaactcttcc ttggtcattg gacagttcag ataagcagct tctcccttat
      841 catatcgcga ttttaaataa accctatcca tgttaatggt tgacttatcg acaattggag
      901 ctgctgcgtc gtaaaaataa aagccagcac caccatttaa ggcatgtatt ttttcagcaa
      961 ggctgtcact ggtcaagggg ccagttgcaa ttactgtaat agcatcgcta ggaatgtcaa
     1021 taacctcctc acgaatgatt tcaatcagag ggtgattttc aagctcagct gtaacagcct
     1081 tggcatagcc ttcgcgatct acagccattg ctcctccggc agggacacga tgggcttcgc
     1141 cagcacgcat aataatcgaa tccagacgac gcagctcttc ctttaaaagc cctactgcgt
     1201 tggttaagct gtcaccacga aaagagttgg agcaaaccaa ttctgcaaaa tgggtggttt
     1261 tgtgttgcgg tgttgccttg acaccacgca tctcatatag cttaacagga ataccacgct
     1321 tagcaatttg ataagctgcc tctgatccag ctagaccagc accaataaca ttaatataag
     1381 attgagacaa tagaccaata cctctttggg gacttatcca tcactgattg ccccgcaact
     1441 ctttctttca agtaattacc ctgcctatta taacagaaat aagagcaaag caaaagaagg
     1501 agctgaacag cctcagtctt ttatataaag gagataagcc cgtacctgca cgctctccac
     1561 aaagctagct gcttcaagca ttttagcttt cgcccaatac cagctatcca catatcttgt
     1621 tcactgcagt agttactgga aggcttttta aggcttattt ttcaaaatct agccaaaaat
     1681 atttcaccgg acctcatcat cttgctggta gcagctaaac aagccttttc cagtaaaaaa
     1741 aaagcaagcg aaagcctgcc cttgttcttg tttagaaaaa acacatccat gctgcgataa
     1801 agacacttaa gacactaaac agcgatccaa tcaaataata ttcagcaaag gctgggcttt
     1861 cagagatttt attgtagcga gcaatagact tagcggtaag caccagtccg attgaagcaa
     1921 attgtcccaa caccatacaa acgcccataa caatacgctc taaattacca atagccgcac
     1981 ccgcccctac aatggtatcc attggtttat cactagctgg ctggaattta ttgaagcaga
     2041 gcttaaagat aatattgaca ggcttggtga tcaaaaccat aaaaagcact aacaataact
     2101 gccgagcatg taaccaatca gggatctcag cctgattaac acgagcgact aaagccagaa
     2161 taatgaaaag atgcaagagc tggtccaaca caaagaccca cgaccgatca agcttaatga
     2221 tacgagccca ttttggctta aaataatcaa taaccgcatg gctactaaaa ataaggatcg
     2281 ctgttagcca aagcttaggt atacacatca ccactagaaa caatggagca gctaccccta
     2341 ataagtgcag ccccagataa gcaagctgct cctccttctt atcagcaata acctgactct
     2401 gaaggtgata atctgataaa aaatgacaaa tcactagcag cactaaaata ggatgctgat
     2461 aaaggtaatc agataagccc tgcataggtg gctcctttcc tctttttatt cttgtaggta
     2521 ggtcaaagct gcatggcgac ttctaagata aacctttaca ctgctgcttt ttaagcgctt
     2581 tgacaaggca cttgattgga ggtccaatgt atcgccaatg agctgttggt caaattgttc
     2641 ttcatagatc cctaagtcta aaagcgcatg aaacacctct aattgactag cacgccagct
     2701 agcttttatc gcctcaccag ctgctaaaag gctattgagc accagatcct tgtgctcctt
     2761 atcagtccgt atagctacct gggtattgcc ataatcattt ttttgatgaa tgtaatgaat
     2821 agcctctctg gcacgccaat aggctggacc gtcagcacca atactaatat cagggttaat
     2881 atcagtcaaa atagtcccct gtccaatacc aaacctaaca gggtagcctg tcatggcttg
     2941 attaattaaa tcaatgagtt gaaaaacagg cgcatcatta gtcaacaagc cttgaaattc
     3001 atcacccaga gtcacagata agttagagac gatataggaa gaaaaatcat ggttgagctg
     3061 atccagacag gcctttaagg actcttgcac caaagaacgc gactgaattt gcttagaatg
     3121 gaccaaatcc ccaataacag cgatatatag catgattttc cctcctttta tgacttccat
     3181 tataacagac aaaaaccaaa aagtccatta taatggaaaa tcatctatat ttccgttata
     3241 atggacctct gctaaaatag ttcaaaccta ctttacaatc tcttctttat agtcacagac
     3301 ttcattgcta cacacaacct gcttacctcc acgaattttt ttctcaacaa ggtaatcgcc
     3361 tgacttcgga caagaccgtc ctaccggcaa atcccacgag gtaaagtcac actcagggta
     3421 gcggtcgcag ccatagaaaa tacggttacg ctttgttttg cgctcaatga cttggccttg
     3481 ctgacaagct ggacaagaaa ctccaatttc ctttgtgatg gcctttgtat gatggcactc
     3541 aggaaagtta ctacaagcat aaaacttgcc aaatctaccc agcttaacaa ccatcgggtg
     3601 gccgcacagc tcacaatcaa aaccagccgg ctcgtccttg atttgaattt tttcgatctc
     3661 cgtttcagcc ttggttaact ccttaacaaa tggcttgtag aattggtcaa tcacattctg
     3721 ccaggcttct ttgccgatct ctatctgatc aagcttatct tccatatcag ctgtaaattt
     3781 gacatcaaca atatcaggga agaattccac aatcaattga ttaacaattt cgcctaattc
     3841 cgtcggctca aagcgtttag cagccagctt aacataataa cgacgctgaa tcacatcgag
     3901 tgttggagca taggttgatg gccttccaac accgttttct tccagtgttt taatcaggct
     3961 tgcttctgaa taacgagctg gcggttgagt aaagtgctgt tcaggtgtta aggtaacctt
     4021 tttaaccact tctccttctg tcatttcagg aagcatcttg cttttatcag aatcattgta
     4081 aacagccata taaccgtcaa atttcatctg actgccattg gcaacaaaaa ggacactatt
     4141 ttgctctagg ttaaccttaa cagtatcaaa cacagcagct gtcatctgac tagcgacaaa
     4201 gcggttccaa atcaaggtat agagctttag ctgatcctta tctaaaaatt tagcaatagc
     4261 ctctggcgta tggttcacat tagatggtcg aatagcctca tgagcgtctt gagcaccagt
     4321 agcattttta actcgattgc catgcttaga gtactgacta ccgaaacgtt caacaataaa
     4381 gcctgcggca tcattttgag caactgggct gatacgagta gagtccgtac gcatgtaagt
     4441 aattaaccct tgtgttccat taggaccaag actaatcccc tcataaagct gctgagcaac
     4501 catcattgtt ttacgagtcc gaaagttaat cttattggct gcgtcctgct gcaatgagga
     4561 ggttgtataa ggtaaaggag catgacgcct gcgttctttt ttctcaacct tactaaccat
     4621 aaaatcatcg ctacttaatc gagacaaaac aagcttaaca tcatcattgg tattgagctt
     4681 catctttttg ccattgaggc cgtaaaagct tgcttggaat ttttttgtcc cttttttaaa
     4741 gagaccatca attgaccaat attcttcagg aacaaaggcc ttaatctcat gctctctgtc
     4801 aatgattagc tttagagcaa ccgattgcac gcgccctgct gaaagcccct ttttaacctt
     4861 tttccagaga attggcgaaa tggaataacc aacaatacga tccagtacac gacgtgcctg
     4921 ctgtgagtca accaaatcca tatcaatttt tcttgggcct tcaaaagctt ctttgacggc
     4981 atcctttgtg atttcattga aaacgacacg attgttatca tcaggatcaa gtcccaaaat
     5041 atgtgataaa tgccatgaaa tggcctctcc ctcacgatcc gggtcacttg ctagataaac
     5101 ctttttagca ttctttgctt ctttttttaa ggcattaatc agcggaccct taccacgaat
     5161 attaatatac tgtggctcat aatgattgtc aaaatcaata gacattgatg attttttcaa
     5221 atcacgaata tgaccaaccg aggcaacgac cttatactga cgtcccaaat atttttcgat
     5281 ggttttagcc ttagcaggtg attcaacaat gactagattt tttttagcag ctgctgattt
     5341 tttctttgta gcagatcttt tcgtctcttg ttttgactta gttgctgttt ttgttaccaa
     5401 ttgacacact tcctataaca gttatggtta aagcttctag cataatatcc cattttttaa
     5461 gaactgtcaa caaaaaattt tctataaata ggaagaaaag ttaagaatag tggtattctg
     5521 aaagaatgtc tctgccatga gtgacacagc tggcaccatc tttgatcagc ttcaaacagc
     5581 ccgccgatgt cccattaaga atattgtcag gtacgacaaa aatatcacgt ccctcttcca
     5641 tagctagctg acaggtaatc aaagagccag agcgctgctt agcctcaaca acaaggacac
     5701 ctcgactaag acctgcgata atacggtttc tttcagggaa atgataagac aaggcggcct
     5761 ctccagcccc atattcactg agcacgagat gacgctgaga taaaaactcc tgtagctggt
     5821 gattttcctt tggatagtag cgatctaggc cagtcccgat aacagctatg gtttgcccac
     5881 ctgctttcaa gcaagcgaga tgagcactgg tatcaatacc tctagcaagc ccgctgacaa
     5941 tgacaaagtg attcttaagc tctttgatga ttttgtaaac agaccgcgtc ccaatttcac
     6001 tggattctct agagccaacg actgccagct taggcttttc taacaggctt aaatcacctt
     6061 gataaaagag taaaacagga ggattataga tttccctcag ggccaatggg tattgcttat
     6121 ctaggataga taagctcgga aactggttga attccttttt taacaaggcg acatttaatt
     6181 gcttgtaggt ctcaataaat aaaactggat ttttgcagca agaaaccact gccatatctc
     6241 taagggatag agacttgtta ttacgctgct ggtagtcaat caggttaaga atatttaaat
     6301 tagttagccc agcctttttt aatttataaa gttcaaaatt attcatcact gtacctctct
     6361 aatgatttat tcgtaaaaaa attaaaaaag ctctgactaa acaaagcttt ttgcaaactc
     6421 ttgaggagct gtacaggatt ccagcaaaaa aatcgaggcc tcctagcctt tgtatgagca
     6481 ttgtagggca gctcatcaca tagcattcca ttgaaaaata ccagaattgt agatccacct
     6541 agtggctatc gtttttgctt tcggcagcta ccttttctca aaatgagatt tttagcgtaa
     6601 gatcattgat tttatcggct caaagctttg ccgatgaatt ggtgtgacac catactggtg
     6661 caatccctgc aggtgctcct tggtcccata gccggcattt ttagcaaagc catagcctgg
     6721 aaaggcctta tcgtaatcaa gcatcaatcg atctctggta accttagcca caatagaggc
     6781 tgcagcgatt gacatagagc tcgcatcgcc ttttataata gcctgttgag gaatagaaac
     6841 ctctagtgtc atggcatcaa tgagcaggta atcaggctta ctcacagagc cctccagctg
     6901 attaatggca gctgtcattg ctaattttgt tgcttcatag atattaaccc ggtcaatggt
     6961 atggttgtca ataattccaa gaccgattcc caacgctttc ttttgaatgg cttggtaaat
     7021 tgcttcatgc ttagctttag gaattttttt agaatcattt agccccttaa tggtgcagcc
     7081 ctttggcagt ataacacagg ctgctacaac tggtccagcc agaggacctc gaccaacctc
     7141 atctatacca gcaatcgctt gaaagccttt ttggtaaagc gcctgttcat acgtcaacat
     7201 cgcctcaagc cgggcttcct cttttaagat agcctctaaa gccctttttc tgctagatac
     7261 agccttttga acgccaagcc gcttatccgc ctttagctct tcaaaaaatg gatcagaaag
     7321 actagaaaca gcttctagac gagctttaat gtctttaata gtcattgctg tcatcatcac
     7381 caacctgatc taaggtgtac tgaccaagtc ttccatcacg aatatccttg atgaataagc
     7441 tgtaaaaacg atcatagtct tccttaaagc caagctgacg tgtcaaggac atgatgattt
     7501 ctggagcgtc agcctctaga tcaatagcct taaaacgctt taataggcga ttaggataat
     7561 acttcttaaa ataattcaat ccaaaaatcg tgacctcgtc cattggcaac agctgatcct
     7621 taatagcccc tgtcagggct aattttaacc caaccaattc gtcttcaaac tttggccata
     7681 agatacccgg agtatccaat atctctagtt ctttattgga ttttagccat tgctgtccct
     7741 tggtcactcc tggcttattg cctactgtgg caattttttt tcccgccaag cgattcatca
     7801 gggttgattt gccagcattt ggaatgccaa taatcatggt tcgtagcgtt tctttttgaa
     7861 tgcctcgttc tcttaagcga cgtagtttat ctgccatcaa ttccttagca gcctcggtga
     7921 cccttttgac cgtagcctgt tccttagcat tgatagctaa tgtcttaatc ccttgcttct
     7981 cataatattg ttgccatttc ttagtatgcg tgttatctgc tagatcagcc ttattaagaa
     8041 gcattagctt gggcttatct ccaacaattt tggtcagcat aggattttga cttgataaag
     8101 gtagcctagc gtctactaaa atcgtcacaa aatcaacatg cttaatattt tcctgtacct
     8161 gtctccttgc cttggacatg tgtccaggaa accattgaat cgtagccatg tgtgtaaaat
     8221 cctttcgtat caagggtttt tagcccctcg tcttttaaaa atcatgcgag tcaccaaaaa
     8281 atcaccaaat attaagcatt atctccagac caagcgatat aattgcaact tgttttggtt
     8341 atttttaatg ccaacaatat caaatgattt ctaatggtat ctggcttata gctattctct
     8401 gctgaataga ttgcctcttc aattttaccc tgtaatctcg ctcagcctgt ctcctgacct
     8461 tgcttttaca tatgaaactg taatattttc cattttacca gttatatgat aaagaaaatc
     8521 aaaatagtcg tagtagaata aattacttta aactattata gcacgatttc ccttatttta
     8581 ctgctaaatt atcctttgta aaagaagata ttaatcgtta taaagaccaa aaaagagaag
     8641 accaaaatga tcccctctag tcttcttttc ggcatatttt accgttattt ggccaacttt
     8701 ccactaatgt gagtaaaatt gtattct
//
LOCUS       DARYXS010000080         8658 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.081, whole genome shotgun sequence.
ACCESSION   DARYXS010000080 DARYXS010000000
VERSION     DARYXS010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8658
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.081"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            113..355
                     /locus_tag="TV193_001554"
     CDS             113..355
                     /locus_tag="TV193_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513732.1"
                     /translation="MISCTLLASLLLTGCHSLSLQLAEAVQEKPIQAVTVEDLTRHGI
                     AESLKAYLQTMGLTNEEAMKQYEEVLSDEIIQYFSS"
     gene            complement(477..1691)
                     /gene="thiI"
                     /locus_tag="TV193_001555"
     CDS             complement(477..1691)
                     /gene="thiI"
                     /locus_tag="TV193_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEL1513733.1"
                     /translation="MKYSEIMVRHGELSTKGKNRMRFINRLKANIQDVLSAYSEVTVR
                     STRDRTHVLLNGADDRSVIEALKPVFGIQGLSPVYKVEKSVPVLIAAVQEIMSSLYRE
                     GLTFKISSKRSDHQFELDSRDLNHTLGAAVFEALPHIKAQMKNPDVTLKVEIRDEAAY
                     LSHEDIKGAGGLPVGASGKGMLMLSGGIDSPVAGYLSLKRGVEIEAVHFASPPYTSPG
                     ALRKAKDLTQRLTRFGGNIQFIEVPFTEIQEEIKHKAPEAYLMTLTRRFMLRITDAIR
                     EKRKALVIINGESLGQVASQTLESMQAINAVTSTPIIRPVVAMDKLEIIDIAQQIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLANVERYESRFDVDGLVERAVAGIRVTEITPEIE
                     TDSLSTLIEELL"
     gene            complement(1693..2835)
                     /locus_tag="TV193_001556"
     CDS             complement(1693..2835)
                     /locus_tag="TV193_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1513734.1"
                     /translation="MIYFDNAATTKPYEEALKTYQEVASKIYGNPSSLHQLGANASRI
                     LEASRRQIAALLDVEAKEIFFTSGGTESDNWAIKGIAFEKSHFGKHIIVSAIEHPAVR
                     ESAKWLESQGFELSYAPVTDKGVVDVKKLAALIRKDTILVSIMAVNNEIGSIQPIAAI
                     SELLADKPTITFHVDAVQAIGKLPVEAYLTARVDLASFSGHKFHAVRGVGFLYKKSGK
                     RITPLLVGGGQEDELRSTTENVAAIASMAKALRIITERQDRSQARIAAMKKVIYQALQ
                     AYEDTILFSEIDDFAPHILTFGIKGVRGEVIVHAFEKHEIYISTTSACSSKVGKPAGT
                     LVSMGIPAALAQTAVRISLDDDNDMGQVEQFLTIFKQIYEKTQKVR"
     gene            3075..3515
                     /locus_tag="TV193_001557"
     CDS             3075..3515
                     /locus_tag="TV193_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513735.1"
                     /translation="MSSHYSRQQKPKKSASIPTKHIKTGFTALQKTIALVGSVLSIVV
                     ATITINRALQPSNEQPKSDSSPSSTSTIVKIIEKESSHSNKEETDKTETNSDSSGTQA
                     THTTPSSADPATKDTEKQQNTETEAPAANQPTANEPAPNSTSNP"
     gene            complement(3585..4937)
                     /gene="gorA"
                     /locus_tag="TV193_001558"
     CDS             complement(3585..4937)
                     /gene="gorA"
                     /locus_tag="TV193_001558"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEL1513736.1"
                     /translation="MAIQYDYIVIGGGSAGIASANRAAMYGAKVLLAEGKAIGGTCVN
                     LGCVPKKVMWYGAQVAETIHTYAKDYGFTVLEDRFDFKTLKSNRQAYIDRIHASYEKG
                     FEHNGVDRIYDYARFIDQHTVDIAGKTYTAPHILIATGGQPIFPDIEGAELGISSDGF
                     FALDDIPKRTAVVGAGYIAVEIAGVLNALGSQTDLLVRYDRPLRTFDQDIIQVLVDEM
                     KVSGPRLHTNADVTKVTKANDGSLQVHLSDGRRLEVDQVIWAIGRKPNVTGFGLEHTG
                     VELDKKGYIAVDAYENTSVDGIYAVGDVNGKLALTPVAVAAGRRLAERLFHNKPNEKL
                     DYNKVATVVFSHPPIGSIGLTEEAAIQAYGQAAVRVYQSQFTSMYTAITSHRQPCLMK
                     LIVAGEEETIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGAEEFVTMR
                     "
     gene            complement(5131..5472)
                     /locus_tag="TV193_001559"
     CDS             complement(5131..5472)
                     /locus_tag="TV193_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEL1513737.1"
                     /translation="MSQDIYDYANKLERAVRALPEYRKALEAREEIKADEAASQLFDE
                     FVAVQEKLQGLMQTGQLPTETEQADIQALSQKIEANDLLKGYFNAQQALSVYVNDIER
                     IVFAPLKDLAK"
     gene            complement(5533..6699)
                     /gene="aroC"
                     /locus_tag="TV193_001560"
     CDS             complement(5533..6699)
                     /gene="aroC"
                     /locus_tag="TV193_001560"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEL1513738.1"
                     /translation="MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYG
                     RGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRK
                     ITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAILTELGIETANH
                     VLVFGGIEVAVPEAMSFADIKKVAESSDLSIVNPKQEATIKAHIDQVKKEGDTLGGII
                     ETLIHGLPAGLGSYVQWDRKLDAKIAQAVLSINAFKGVEFGMGFDMGYQKGSQVMDDI
                     IWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKAT
                     VERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF"
     gene            complement(6812..7492)
                     /locus_tag="TV193_001561"
     CDS             complement(6812..7492)
                     /locus_tag="TV193_001561"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEL1513739.1"
                     /translation="MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSV
                     APAIFEKFAGREIIFTLRTSQEGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKA
                     VFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRI
                     LHVLESED"
     gene            complement(7489..8652)
                     /locus_tag="TV193_001562"
     CDS             complement(7489..8652)
                     /locus_tag="TV193_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEL1513740.1"
                     /translation="MNKVCINPLVERKIAAGIQLLDEKDFDGTIWDYQLVQLVNSSHQ
                     LIGTAYLSKQHKGVGWYLGRSVKKLSVSYFVTLFKTAKKKREHFAASEWTNAYRLFNQ
                     DGDDFGGLTIDLYKDFALFSWYNVFVYQEKELIIQAFREVFPEVRGAYEKIRFKGPDK
                     ETAHLYGAFAPDTFTILENGVAYQVFLNDGLMTGIFLDQHEVRRGLVDGLALGKTVLN
                     LFSYTAAFSVAAAMGGAVETTSVDLAKRSRELSKAHFVQNQLDLSSHQLVVMDVFDYF
                     KYAKRKQLSFDLIIIDPPSFARNKKQTFSVSKDYHQLIAEALDLLAPKGTIIASTNAA
                     NMTVNQFKKQIIKGLGGRPLAQMTLEQLPSDFTINKADERSNYLKVFTIRVRE"
BASE COUNT         2541 a         2057 c         1617 g         2443 t
ORIGIN      
        1 ttttgaacat aaaatacgaa tattatacta aaaataaatc caaatagttt acaatttatg
       61 gttgttttca tataattttc atgaaaggag ggaaatatat gaaaaatcta tattgataag
      121 ttgtacacta ttagccagtc tcttattaac tggctgtcac tcattgtctt tgcagctagc
      181 tgaggctgtt caggaaaagc ctattcaagc ggttacggta gaggatttga ccagacatgg
      241 cattgccgaa tccttgaaag cctacctaca gacgatgggc ttaaccaatg aagaggctat
      301 gaaacaatac gaggaggtcc tttctgatga gattatccag tattttagca gctaaataag
      361 agaatttgag caaaatcagc taaaaacaaa agccagagcc tttaataact aataggtctg
      421 gctttttttg actgtttaga tagactgctt atgttgtagg gctaggtgcg cacctcctac
      481 aacaattcct caataagcgt tgataagctg tcagtttcga tttcaggagt gatctcagtt
      541 actctgatcc ctgccactgc tcgctcgacc aatccgtcga catcaaagcg agactcatat
      601 cgttcaacat ttgctagctt gggattggtt ttgggacgat caggagcaaa aatagtacag
      661 cagtcttcaa agggctgaat ggaaatatca aaggtgtcaa tttgctgagc gatatcaatg
      721 atttctagct tatccattgc cacaactggt ctgataatcg gagttgaagt gactgcatta
      781 atagcctgca tgctctctaa ggtctggctt gcaacctgtc ctaagctttc accgttaata
      841 atcactaaag cctttcgctt ctcacgaata gcatctgtga tccgcagcat gaagcgtcta
      901 gtaagtgtca tcaaataggc ttcgggtgcc ttatgcttga tctcctcttg aatctcggta
      961 aatggaacct cgataaactg tatattacct ccaaaacgtg ttaagcgctg cgttagatcc
     1021 ttggcttttc ttagcgcacc aggactggta tagggtgggc ttgcaaaatg cactgcctca
     1081 atctcaacac ctcgtttcag ggatagatag cccgcaaccg gtgaatcaat accacctgat
     1141 agcatcagca ttccctttcc tgaagctcca accggcagcc ctccagctcc ctttatatct
     1201 tcgtgagaca gataagcagc ctcatcacga atttcgacct ttagggtaac atcaggattt
     1261 ttcatctgtg ccttgatatg cggcaaagcc tcaaagacgg ctgctcctaa ggtgtggttg
     1321 aggtcgcggc tatctagctc aaactgatgg tcactacgct tgctggatat tttaaaggtt
     1381 agcccttcgc gatacaagga gctcataatc tcctgaactg ctgctatcag tacagggaca
     1441 cttttttcaa ctttatagac aggagataag ccctgaatac caaacaccgg ctttaaggct
     1501 tcaatcacag acctatcatc tgcaccatta agtaaaacat gggtcctgtc tcgagttgat
     1561 ctgactgtca cctcagaata ggcagaaaga acatcttgaa tattagcttt tagccgatta
     1621 ataaaccgca tacggttttt tcccttggtc gataactccc catgacgaac cattatttct
     1681 gaatatttca tattatctaa ccttttgtgt tttttcataa atctgtttaa aaatcgttaa
     1741 aaattgctca acctgtccca tatcattatc atcatctagg ctgatacgga ctgctgtttg
     1801 agccaatgct gctggaattc ccattgagac taaggttcct gccggctttc caacctttga
     1861 tgagcaggca ctcgttgttg atatataaat ctcatgcttt tcaaatgcgt gcacaataac
     1921 ctctccacga acgcccttta taccaaaggt cagaatatga ggagcaaaat catctatctc
     1981 agaaaagaga atggtatcct cataggcctg caaggcttga taaataacct ttttcatggc
     2041 tgctatcctt gcttgagatc tatcctgtct ttctgtgatg atccttaaag ccttggccat
     2101 acttgcaata gctgccacgt tttcagttgt cgaacgtagc tcatcttctt gaccgccacc
     2161 gaccaataag ggagtgattc gctttcctga ttttttataa agaaagccaa caccacgaac
     2221 agcatgaaat ttatgaccag aaaaagaagc taagtcaaca cgcgcggtta agtaagcctc
     2281 aacaggaagc ttcccaatag cctgaacagc atcgacatga aaggtaatgg tgggcttatc
     2341 agccaaaagc tctgatatgg ctgcaatcgg ctgaattgac ccaatctcat tgttaaccgc
     2401 cataatggaa actaatatgg tatcttttcg gattaaggca gctagctttt tgacatcaac
     2461 aactccctta tctgtgacag gagcataaga cagctcaaag ccttgacttt ctagccattt
     2521 ggcgctttct ctgacagctg ggtgctcaat ggctgagaca atgatgtgct taccaaagtg
     2581 agatttttca aaggcaatcc ccttgatagc ccaattgtcg ctttccgttc cgccagaggt
     2641 aaagaaaatc tctttggcct ctacatcaag taaggccgct atttgcctgc gcgaagcctc
     2701 caatatacga ctggcattgg ctcctagctg atggagacta gagggattgc cgtaaatctt
     2761 actggccact tcctgatacg ttttaagtgc ctcttcgtaa ggcttggtag tggctgcatt
     2821 atcaaaataa atcatgtgtc accttcattt ttattcaata ctttattgta tcacaaattt
     2881 gatgaaatga aaaaatagat ctttttgcag gataggacaa ctctatccta gacaataagg
     2941 taaaccgttg acttgatttt tgttctagat tatactggta gatgatagag ctaagtctga
     3001 aatgcctgtt agccattaaa gacctaaagc atttgacttt agctagccta tgactcgtta
     3061 aaggagatat tctcatgtca tcacattatt cacgtcaaca aaagcctaaa aaatcagcaa
     3121 gtattcccac aaagcatatt aaaactggct ttaccgccct tcaaaaaacc attgccttag
     3181 ttggtagtgt tctgagtatt gttgtagcga caatcactat taatcgagct ctacaaccat
     3241 caaatgagca acccaaaagc gattcctctc cgtcatcaac atcaacgatt gtgaaaatta
     3301 ttgaaaagga gtcgtcacac tcaaataagg aagagactga caagacagaa actaattctg
     3361 attctagcgg tactcaggcg acacatacta ctcctagctc agctgatcct gctactaagg
     3421 atacagaaaa acaacagaat accgaaacgg aagcaccggc tgctaatcaa cccacagcta
     3481 atgagccagc tcctaacagt acaagcaatc cataacacaa aacacgataa caggcaattc
     3541 agataagctc tgaattgtct gctatcgtgt tttatcatgt gctgttatct catggtaaca
     3601 aactcttcag cacctgtagg gtgaatggca acagtattgt caaaatcagc cttagtagcc
     3661 cccattttaa tggcaacagc aaagccttga atcatctcat caacaccata accaatacca
     3721 tgcagaccaa cgatggtctc ttcttctcct gcaacgatca atttcattag gcagggctgg
     3781 cgatgactag taatagctgt atacatggac gtaaattgtg attgatagac acgaacagcc
     3841 gcttgcccat aggcttgaat agctgcctct tctgttaagc cgatcgagcc aattggcgga
     3901 tggctaaaga caactgtcgc aaccttgtta taatcaagct tttcattggg cttattatga
     3961 aacaagcgct ctgccaagcg acgacctgct gcgacagcga ctggggtcaa agcaagcttt
     4021 ccattaacat caccaacagc atagatgcca tcaacagatg tgttttcata agcgtcaaca
     4081 gcaatatagc ccttcttatc cagctcaact cctgtatgct ccaagccaaa gcctgtcaca
     4141 tttggcttgc ggccaattgc ccaaatcact tggtccactt caagcctacg accatcggac
     4201 aaatgcactt gaagagagcc atcattagcc ttggtaacct tagtaacatc ggcattggta
     4261 tgcagccttg gtccagatac cttcatctca tcgaccagaa cctggataat atcctgatca
     4321 aaggtcctca gtggcctgtc atagcgaacc agcaaatccg tctgagaacc tagggcattg
     4381 agcactcctg caatctcaac agcaatatag ccagcaccga caactgctgt tcgttttgga
     4441 atatcatcta aagcaaagaa accatctgag ctaatcccca gctcagctcc ttcaatgtca
     4501 ggaaaaatag gctgaccacc agtagcgatt aaaatatggg gggctgtata ggtcttacct
     4561 gcaatgtcaa ccgtatgctg atcaataaat cgtgcataat cataaatacg atcaaccccg
     4621 ttatgctcaa agcccttctc ataagaggca tgaatacgat caatataggc ctgacgattg
     4681 ctttttaagg ttttaaaatc aaacctatcc tctaacaccg taaacccgta atccttcgca
     4741 taggtatgaa tcgtttctgc tacctgtgcg ccataccaca tgaccttttt aggcacgcag
     4801 cccaaattaa cacaggtccc tccaatagcc ttgccctcag ctaataggac cttagcaccg
     4861 tacattgctg cacgattcgc cgaggcaatc ccagcgctcc caccaccaat cacaatataa
     4921 tcatactgaa ttgccattaa tttaccacct ttactcttaa tgcttgcctc aatagatttg
     4981 ttattaagct atcattattg ctttatttta atctactgtc atttgactat aacataaaat
     5041 aacttgtgtc tcaaatccct gctacgacaa aaaaagattg tgataagcat caacaatcct
     5101 ttcttctctt aatcctaagc cagcttagct ctacttggcc aaatccttca atggtgcaaa
     5161 tacaatccgt tcaatatcat taacatagac ggaaagagcc tgctgagcgt taaaataccc
     5221 ttttaatagg tcattggcct caattttttg gctgagagcc tgaatatctg cctgctctgt
     5281 ctctgttggc agctgaccgg tctgcatgag tccttgcaat ttttcttgca cagcaacaaa
     5341 ctcatcaaat agctgactgg cagcctcatc tgccttaatc tcttctctgg cttccaaggc
     5401 cttgcgatac tctgggagcg cacgaacagc tcgctcaagc ttattggcat aatcataaat
     5461 atcttgggac atctggatct ccttttatca tttattatcc ttatcatatc acaatatcaa
     5521 gccatttgtc gcttaaaaat gatgaacata gtcacgatag gcaaaaaaag cctgctttaa
     5581 atcggtcata ttgtctgatg gaaattgttc caaaatctct tttgtgatga cagttgctac
     5641 aacattttcc atcacgacac cggcagccgg cagagccgta ggatcagaac gctcaacagt
     5701 agccttgtaa ggctcgtgcg tctcagtatc cacagacatt aggggcttgt agagggtggg
     5761 aatcggcttc atcacccctt tgacaacaat aggctgacca gtagtcatac ctgcctcaaa
     5821 gccacctagt cggtttgttc gacgactgta gccgcttgtc tcatgccaaa tgatgtcgtc
     5881 catgacctgc gagccttttt ggtagcccat gtcaaagccc ataccaaatt cgaccccttt
     5941 aaaggcgttg atagacagga cagcctgcgc gattttggcg tctaatttac gatcccactg
     6001 aacatatgaa cctaagcctg ctggtaagcc atgaatgagt gtttcaataa taccaccaag
     6061 cgtatctcct tcttttttga cttgatcaat atgggccttg atagtcgcct cttgcttggg
     6121 attgacaata gataaatcag aagactctgc tacttttttg atatctgcaa aggacatcgc
     6181 ctcaggcaca gctacctcga taccaccaaa aactaggaca tgattagcag tttcgatccc
     6241 aagctcagta aggattgcct tagcaattgc accaacggcc acacgcatcg ctgtttctct
     6301 ggcagaggag cgctcaagcg catttcttaa atcatcaaaa cgatatttga tccccccaac
     6361 caagtcagca tgaccagggc gtggacgagt gattttacgc ttgaacttga tttgctcttc
     6421 aacagcctca acagccataa tgtctagcca tttttgatgg tccttgtttt gaatggttaa
     6481 agtaattggt gctcctgttg ttttgccatg acgaacacct gaagagatat gcacacgatc
     6541 tgattcaatg cgcatgcgtg cgccacgacc atatcccccc tgccgacgct tcagttcctt
     6601 gttaataagc tcagctgata atgctaagcc tgcaggaatt ccctctataa tggccgtcaa
     6661 agcttgtcca tgtgactcac ctgctgttaa atacctcatt attcctccat ttatcaatca
     6721 tagacataaa aagcaaacct gccctcctct agacaactaa aagacattat tctaagctat
     6781 ccaagagaat aatgtctgtt accgtatctt atcaatcctc agattccaaa acatgaagaa
     6841 tccttttcat atcagccaag gaaacctgcc ctggtgcact ggcttgatct aaggacacaa
     6901 aagtccacga ggaccctaca acatcacctg ccaagcgtga tagtctgcct agctttccca
     6961 ttgacatggt tgcaaattcc tgctctgggt taagtgtttt aaagcctctg gtataattca
     7021 tcaaatccaa aacgtcctgc tcgctctgtg gcatgacagc aatcttgaca acgcgaggag
     7081 ctagcttagt catctccgaa aaagcctcca tcagattttc aggcgtctca tcaaaattgt
     7141 gataagacaa gacaagattc ggaaagtcaa gcatttcatg aaagacagcc ttgtgactaa
     7201 agtattcaaa gtcaatatag tcaggattat aaatcgcatt gatctccttg atcaaatcaa
     7261 cgtattcctg atcagaaagt gtaatatgcc ctccttcttg acttgtacga agggtaaaaa
     7321 taatctctct acctgcaaat ttttcaaaaa tagctggcgc tacagaaaca atatcctcct
     7381 taggaagaaa gtctgctcgc cactcgatta aattaacatc ttgatattta gaaacgtcga
     7441 tagattgagc ctcttcaaca tttcttggca tgactggtgc tacaattttc attctcgtac
     7501 ccttatagta aataccttta aataattact tctttcatct gctttattga tagtaaaatc
     7561 acttggaagc tgctcaagtg tcatctgagc taatggcctg cctcccaatc ctttgataat
     7621 ttgcttttta aactggttaa cagtcatatt ggcagcattt gttgaagcga taattgttcc
     7681 cttgggggcc aataggtcta gagcctcagc gattaattga tggtaatcct tactcactga
     7741 aaacgtctgc tttttgtttc tggcaaagct tggtggatca ataataataa gatcaaaaga
     7801 aagttgcttt cgcttagcat acttaaaata gtcaaaaacg tccataacca caagctgatg
     7861 actggatagg tccaactgat tttgaacaaa atgagccttt gataactctc tggagcgctt
     7921 tgccaaatca acagaggttg tctcaactgc accgcccatt gctgcagcta cagaaaaagc
     7981 tgctgtatat gagaacaggt ttaaaacagt ctttccaagc gccaagccgt ccaccagacc
     8041 tcgtctaacc tcatgctgat caagaaaaat ccctgtcatc aagccatcat ttaaaaatac
     8101 ctgataggct acgccatttt ctaaaatggt aaaggtatca ggagcaaacg cgccatacaa
     8161 atgagccgtc tccttatctg gtcccttaaa gcgaatcttt tcataagctc ccctgacctc
     8221 aggaaaaacc tctcgaaaag cctgaataat aagctccttt tcttgataaa caaagacatt
     8281 ataccaagaa aataaagcaa agtccttata gaggtctatg gttagtcctc caaaatcatc
     8341 accgtcttgg ttaaaaagac ggtaagcatt tgtccattca gacgcggcaa aatgctctct
     8401 tttcttctta gctgtcttaa ataaggtcac aaaataagaa accgacaatt tcttaacaga
     8461 ccttcctaga taccagccta ctcccttatg ttgctttgaa aggtaagctg tgccgatgag
     8521 ctgatgagat gaattcacaa gctgcactaa ctggtagtcc caaatggtgc catcaaaatc
     8581 cttttcatct agtaattgta tccctgctgc tatcttgcgt tcaacaaggg gattaataca
     8641 gaccttattc atagtttc
//
LOCUS       DARYXS010000081         8123 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.082, whole genome shotgun sequence.
ACCESSION   DARYXS010000081 DARYXS010000000
VERSION     DARYXS010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8123
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.082"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(13..2313)
                     /locus_tag="TV193_001563"
     CDS             complement(13..2313)
                     /locus_tag="TV193_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1513741.1"
                     /translation="MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VANDAISDNIKKAIVSTEDDNFQRHNGIVPKAIFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSADDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKPIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNLFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISIGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            2418..3674
                     /locus_tag="TV193_001564"
     CDS             2418..3674
                     /locus_tag="TV193_001564"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEL1513742.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAREDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            complement(3709..4518)
                     /locus_tag="TV193_001565"
     CDS             complement(3709..4518)
                     /locus_tag="TV193_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1513743.1"
                     /translation="MLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLS
                     HVSLAGVAFGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAIS
                     LIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFVIALIILALTILFIRPMYILTFD
                     EDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKS
                     VIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIAIFLVVNLLSFIRQK"
     gene            complement(4511..5230)
                     /locus_tag="TV193_001566"
     CDS             complement(4511..5230)
                     /locus_tag="TV193_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1513744.1"
                     /translation="MRYISVENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKST
                     LIKATLGILKSRAGQVTIAKQNIHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFTRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLP
                     WRCFNIHDAEADESKGGSFHA"
     gene            complement(5233..5676)
                     /locus_tag="TV193_001567"
     CDS             complement(5233..5676)
                     /locus_tag="TV193_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEL1513745.1"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQEMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITAFAEELEG"
     gene            complement(5746..6597)
                     /locus_tag="TV193_001568"
     CDS             complement(5746..6597)
                     /locus_tag="TV193_001568"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEL1513746.1"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            complement(6812..7336)
                     /locus_tag="TV193_001569"
     CDS             complement(6812..7336)
                     /locus_tag="TV193_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1513747.1"
                     /translation="MVEYWDIYTMNRLKTGRLMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPSYWDITVGGSALAGETSQEAVMRELKEELGLTLDLAGVRPHFSI
                     TFDNGFDDTFLILQAVDVRKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            complement(7830..7931)
                     /locus_tag="TV193_001570"
                     /pseudo
     CDS             complement(7830..7931)
                     /locus_tag="TV193_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT         2433 a         1996 c         1542 g         2152 t
ORIGIN      
        1 tggaaaatac aactaatttc ttctaccact aaaacctccc caggcttttt gatagtctgc
       61 gtctgttcca ccaatggcaa acctataggt agttgctccg ggtccctttt gagcccaaag
      121 gctggttgtt agctctccac cgatggagat ggtttggcca ttgatcgtca ctgtacccgg
      181 ctttagacca gtggccttca agacagaagc cttgataaca ccaggatcca gtgaaaaccg
      241 ctgaccaagg ccaaaaagat tgggatcagc ctgactgatg gcattaacca aataagccat
      301 ataatttgaa ttattattgt atcccgtcag tggtgcaagc gaggtattgt catcatggcc
      361 tgcccaacca cccaaagtaa cccttggagt agctaagacc agccagacat cggtataatt
      421 ttcggttgtt cctgttttac ctatccagtc agcacctgca aggcttgggt tgatccctgc
      481 taatcggctt ttaaaagtgg ttgttgcccc agatgaaatc ggccctctca agagctcctg
      541 taaaatcgtt gctgtcggag ctgagaaaat acgaaccggc ttggcctcat gctgataaac
      601 aacggatcca tcactagctg tgatactagc caccatatat tgcttttgat aaagaccatt
      661 attagcaatc atctgataag cattggtctg ctgggctacc gaggtctcaa tcccaccacc
      721 aagtggcaga ctttcaatgg aataatcagc aatccgatat cccattttac tcatatagtt
      781 ttcaacatca acgcccttat cacgcagcag cttttgagtc caaaaggctg gaatattcca
      841 tgaggtatta agcgcctcct gcaggggcat cattgctgtt ccttcactat cgacgtgcat
      901 gattttttga ccgctggaat aggtcgtcgg atagttggat aggacactag cacttcccat
      961 taatccctga tcaatggcag gtccataagc aataatcggc ttaatgctag agcctggaga
     1021 gcgaacagta ttaaaggcat gattgttttg attttgagca tagtctctcc caccaataaa
     1081 gcccaaaaca gcacctgtag cattgtccgt taggacattg cccatctgca ctgtcccagt
     1141 gccatcatct aacaagccac caaactgagc tgccgctttt tgcatcacct gatggattgg
     1201 cttattgatt gttgttttga cagtgtagcc gccatgctgc agctcagtta aggctcgctc
     1261 ctcataggca gccttagtct catcattttt taaatcttta gcaggcacct tatctcgctt
     1321 aatcagatag ctatacatgg ccttttgtgc ctctgccaag acagaatagt agaggtaatc
     1381 atgagtattg gcagtgactg tttcaggttt gataaaatca ttgctaatag gatatgcctt
     1441 ataatcacga tattcttttt ctgtcagcac acctgttcga tacatattgt agaggacatt
     1501 ttgctggcgc ttaatcccat aggccatatc atcggctgat tttaactgcc ctgtcggcaa
     1561 atacggcgaa taaacaatcg ggctttgcgg aagccctgcc aaaaaggccg cctgcggaac
     1621 cgtcaaatcc ttggcagaga ctccaaaaat gccacgcgca gcctcctcca cacctgcaat
     1681 gttttgtccc ttattattac gaccaaaagg cgacacgttt aaataatgtg ataaaatatc
     1741 gtcctttgac atgtaacgct ctaaggccag tgcatagata atttcctttg attttcgcct
     1801 aaaggtcgga tcatcgccca agacttgctg cttaatcaac tgctgtgtca gcgtagagcc
     1861 accacttgac tccccaaagc ccaaaacaga ggccagagtc gcacgaaaaa tcgcctttgg
     1921 cacaatgcca ttatggcgct gaaagttgtc gtcctcagtt gagacaatag cctttttgat
     1981 attgtctgaa atcgcatcat tagcaaccgg tgtcctaagc agatccgtat caatgcctga
     2041 aatcaagcta ttatctgaat aggtaatctg tgacatcatg gtcaatgatt caacctgctt
     2101 gacaagactt tccttacttg gaatttttac cgagtcaatt tgactggcta aatagccaaa
     2161 ggccatacca gcacccagca tgccaaataa aaagacagct acataaaaaa agctcgacat
     2221 gaattttaat gtgcgcaaaa agaccgttcc aaaatcaact aattctaatc gctgatgatt
     2281 tttgcttgtt tgattctttt tccatttcac cataacgtac ctcaatcttc attataccaa
     2341 actttgatta agcttgcaca gccacagtca tttttgatat aatgattcgg aaatcataaa
     2401 gaaaatggag aaagcctatg aatatttttg aagaactcaa agctcgtggc ttggtctttc
     2461 agacgaccga tgaagaagcc cttgtcaaag cattaacaga agggcaagta tcctattaca
     2521 ctggctatga tccaacagct gatagcctgc atcttggtca tctcgttgcc attttgacat
     2581 cacgtcgctt gcagctagca ggacacaagc cctacgctct tgtcggtggg gcaactgggc
     2641 tgattggtga tccgtccttt aaagacgctg agcgtatcct acaaaccaag gaaaccgttc
     2701 ttgattggag ccaaaagatt aaagaacaac tctcttgctt tcttgacttt gacaacggtg
     2761 aaaacaaggc tgagcttgtc aacaactatg actggttctc acagattagc tttattgact
     2821 tccttcgtga tgtcggcaag cacttcacta tcaattacat gatgagcaag gattcagtga
     2881 aaaaacgtat cgaaaccgga atttcctaca ccgaatttgc atatcaggtc atgcaaggct
     2941 acgattttta cgagctaaat gctaagcaca atgtgacact gcaaatcggc ggctctgacc
     3001 agtggggtaa tatgacagca ggtaccgaat tgctccgcaa aaaagctgac aagactggac
     3061 atgtgatgac agtgccattg attacagatg caacaggtaa aaaattcggc aagtcagagg
     3121 gtaatgcgat ttggcttgac gctaaaaaaa catctcctta cgagatgtac cagttctggt
     3181 taaatgttat ggacgatgat gcggtacgct tcctgaagat cttcaccttc ttatcacttg
     3241 atgagattgc tgctattgag gagcagttca acgcagcacg ccatgagcgc cttgctcaaa
     3301 agacacttgc gcgtgaggtg gtgacactgg ttcatggaga ggcagcctac cagcaagccc
     3361 tcaatattac cgaacagctt tttgcaggag ctatcaaaaa cctttcagca gctgagctta
     3421 agcaaggctt aagcaatgtc cctaactatc aggttcaagc agaagacagc ctaaatatcg
     3481 tggatatgtt agtcacagca ggcatttcac catcaaaacg tcaggcgcgt gaggatttac
     3541 aaaatggcgc gatctacctc aatggagaac gacttcagga tctggattac agcttatcta
     3601 cagcagatcg cattgacaat cagttgaccg tcattcgccg cggcaagaaa aaatacgctg
     3661 tactaaccta ctaatcacag acagctagga aaatcttgct ttggatgatt atttttgacg
     3721 tataaaggac agcaggttaa ccacaaggaa gatcgcaata aaaatcatcg taatggtcgc
     3781 acttgccggc gtttcccaaa aataggacaa gaaaatacca gacagcatgc ctgtaaagcc
     3841 aatcataatc ccaagaaaaa taactgattt aaagtttttc ccaagccgca tagcaatact
     3901 tgctggcaaa accataatcg ttgataccaa aagggcccct gccgctggga tcgttagagc
     3961 aatagcaaca cctgtcacaa tattaaacaa gacagacatg acacgcaccg gcaagccatc
     4021 gacgtaggct gtgtcctcat cgaaggtcaa gatatacatt ggacgaataa ataatatcgt
     4081 caaggctaaa ataatcaaag caatgacaaa taaggcagca acctgctccg tactaatagt
     4141 aatgatagag ccaaaaaggt attgctccaa gctcatacta gaagagctag ttgacttact
     4201 catgataatc aaggaaatag ccagccccaa ggacattagg atagctgtcg aaatctccat
     4261 atagtgctta taaaccaccc taagatattc tagcaagatg gcagctagca ccaccacaat
     4321 aatcgttgtg aaggttggcg aaacaccaag aacaacacca aaggccacac cagccagaga
     4381 aacgtggcta agcgtatcac tcaacaagct ttgacgacgc aaaatcaaaa agatacccaa
     4441 aatcggagca aagatactga tcgccacaac agccataaca gcacgctgca taaaatcata
     4501 agataaaatc tcaagcatgg aatgaccctc ctttgctctc atcagcctca gcatcatgaa
     4561 tgttgaagca acgccaagga agccgttgat ttctaatcaa atgaatattg cgatcagcat
     4621 aagccttgac ctcctctggg tcatgtgtaa tcatcaaaac agccttacca tgtctatgag
     4681 cgctgtggtg catcaactca taaaaagtat ctgttgttcc actatccatt cctgtggtcg
     4741 gctcatcaag cacaaaaata tcggggtcag aagcaaacat acgcgcaata accacacgct
     4801 gcttttgacc acctgataga ctccctattc tcttatgccg actatcccac atgccaacag
     4861 actccaagct tgtccgaaca tgctcctcat cgtgcttact tagtctggta aaccaaccac
     4921 ttctaggata tctgcctgat ttaacaaatt cataaacagt cgacggaaag cctgcattaa
     4981 agctggcaac ctgctgtggc aagtaagcaa ttctcagctt tttcccatga atgttctgtt
     5041 tagctatagt cacctgccca gcccttgact ttaaaatccc caaggtcgcc ttgatcaggg
     5101 ttgacttggc agcaccattt tcaccagtca atgtgacaaa ttctccacta tccaaatgat
     5161 agctgattcc ctctaaaaca ggctcactgt catactggaa cgagagattt tccaccgata
     5221 tgtatctcat tattaccctt ctaactcctc cgcaaaagca gtgataaatt tttcaacaat
     5281 cacctgctcc tccgcagaaa aatgtgccaa caaacgatga taaacagcta gtgttttatc
     5341 gtgatgatgt gtatgctcct tagcgattgg ccttgctaga tcagtcagtt caaaataggt
     5401 tactcgagca tcaacggtat cctttgttcc tgctagcatt tcttgcttga tcaagccttt
     5461 aatcgcttta gttactgctg cttgactgat atttagcctt tttgccaaat ctgtattggt
     5521 tagcttttcc tgtgacaaaa gcatcaaaat atgctcctga gtatttgtta atttgacatc
     5581 actctgacaa gccccaaaga gcagctcatg ctgattttca gcctttaaca aaatacgatt
     5641 aaccaaatta tcaagctttt tttctaaaat tgtcatgatt tccctctcct cattaaccag
     5701 ttaattataa catgacgccc caaaagacgc aacttcaagg ctgatctaca gcgttctaac
     5761 cttgtagact tccttacaaa agcctttcag gctattcacc acacgattgg cctgcttttc
     5821 tgtttgacat agggcaaata ccgttggacc acttcctgtc atcagggcaa tgtctgctcc
     5881 tgactgcagc attttatcct taaccttttg aataaacggc cgtttagcaa tggaaatatc
     5941 ctctaaggaa tttcccatcg ttgcaagcaa gcgctgataa tcacctgcct caatggctga
     6001 aaccagatcc tcaatcggca ctcgagatat cgtctcacaa tcaatatccc aaaaaatcgt
     6061 tctagtagaa atgccaaatt ctggcttcac tagaaccacc caagaggaca agcggccatt
     6121 gattggctta accacctcgc ctttgccagt cacttgggcg cagcctgcaa aaagacaata
     6181 aggcacatcg ctaccaatct gcatgccaat gtcaatcatc tgacggggac taagctttag
     6241 ctgccacagc tgattcaatg ctctgattgc tgcagccgca tcacttgagc cacctcccat
     6301 accagcacaa acaggtaccc tcttatccaa gaaaatagag acacctgttg agatttgaaa
     6361 tcgctctttc agcaaataag ccgccttgta aacgtcattg tgctcattaa taggcaatct
     6421 agggcaatta gaggtcaata aaatcctatc ctcctctaaa tgatccactg taatataatc
     6481 acaaagatct acactaacta gaaccataga taggtcatga tagccatctg gtcgcttgcc
     6541 ttgaatatct aagcctagat ttatttttgc aggagctctc tcaatgattg cagtcataat
     6601 actcctttat ttgatgtcat tatagtatca aatatacaca atcttcatga aaaattcaaa
     6661 taaatacagt tagtatctaa tgatgcatag acagcgtgtt tgtatcaaaa cagccaacca
     6721 tttgtcccta ctagcgtgag gcttcaccag atcagcagcc aaaaaacgac aactactagc
     6781 atagcaagca aagctaagac agcagcagtc tctatgacca cttgatcgct ccatattgcc
     6841 ccactaactc aaagcacata tcaatcttgc tcttaaagta gggaataaaa ataccagcat
     6901 caatcatggc taaaatctca tcacgactag cccatcgaac agcctgtacc tcctctgtct
     6961 gaagaactag cttccttaca tcaacagcct gcaaaatcaa aaaagtatcg tcaaagccat
     7021 tatcaaaggt aattgaaaaa tgaggcctta caccagctaa atcaagagta agtcctagct
     7081 cctccttcag ttctctcatc actgcctctt gtgacgtctc acctgcaaga gcgctgccgc
     7141 ctaccgttat atcccaatag ctgggccaac cctctttatc cttttgccgc tgctgaatca
     7201 gcatttctcc cttgtcatta aagacacagg cgtgaaccac taaatgataa gcaccctcta
     7261 caaaagcagc tccacgctcc atgagtctac cagtcttaag acgattcatc gtataaatgt
     7321 cccaatactc aaccatacaa acacacctcc tgatacagct attaccagat ccagtatatt
     7381 aatcatatca caataagcat atccaaaaca accaggtcca gacaaaacaa caattaccaa
     7441 cctagcttaa ttcttttttc tacaattccc taccttaaaa tgcctcgcat agaaaatgga
     7501 caaaaagatc tgttttcccg agacgtatca aaaagctcac cacgctaaca aactggtagt
     7561 taagatcccc aagcgtctta ctcagttaac gatatggtga tacacacagc tgacttgcct
     7621 catcatatta gttacaaaaa accttaaagg ctcaacccaa aagcacacca actacatcac
     7681 cccatgaaag aggaagacaa aacatctact gctgcaagca aaaagagacc ccattagggc
     7741 ctctctagtg ctcatatcag cttttaaact aatcaatcgc cttcaagcta aaggctatca
     7801 tttagtagga gaaagttgca aaagctaatt tagttgtttt ttctttttag agttagcagg
     7861 cctgcgctgg caatgacgcc gagagctgca agggtgaaga atgggtgatt tgtctctcct
     7921 gtagctggta atataccctt ttgagctgct ggagccgctg atttgcttgg tgctgactta
     7981 ggcgctggta ccttaggact agctgactgc tgctctgaag tctttggtac ctgtggagca
     8041 ggagattgct ccggggcctt tggagctgat ggtttggtat cctttccttg ctcgcccttt
     8101 tcaccgcgtt ggctttgttc acc
//
LOCUS       DARYXS010000082         8083 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.083, whole genome shotgun sequence.
ACCESSION   DARYXS010000082 DARYXS010000000
VERSION     DARYXS010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8083
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.083"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            101..850
                     /locus_tag="TV193_001571"
     CDS             101..850
                     /locus_tag="TV193_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1513748.1"
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLL
                     SAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQ
                     VSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
                     IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERV
                     VYFRNGSSCLIARSKMNSVLTTIENLHRGDN"
     gene            850..2184
                     /locus_tag="TV193_001572"
     CDS             850..2184
                     /locus_tag="TV193_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1513749.1"
                     /translation="MKLILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGF
                     AVFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLSKTLLIFYGLFPITLWSLWYRL
                     LGFFILPLFKLDYHLTNDGFWGIFTDIVSTLMVFLFLRWLRYDFRALRINLLSDRDKR
                     ILGVTNWSMVSYYFLIQLLAYLEYELAVDTYAYRQCMMLGYWIIFMGTVSRLDRSLRD
                     TLQERLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNDSMSIVR
                     SVYQSVFKDSNKRFRKQKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEDI
                     SPQGMELIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFMIENTTKEEKID
                     LSFLYDFGVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(2306..2437)
                     /locus_tag="TV193_001573"
     CDS             complement(2306..2437)
                     /locus_tag="TV193_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1513750.1"
                     /translation="MDKPTRQPKFQELTPSQLTQITGGGWLEGLQKVFNVSKPKLLK"
     gene            complement(2537..3895)
                     /locus_tag="TV193_001574"
     CDS             complement(2537..3895)
                     /locus_tag="TV193_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL1513751.1"
                     /translation="MNPNMFKSAEFYQRRYHHLTTFLTIPLALLLTFLILFSCFVYKE
                     ITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDSIIQYAKDLEESQKQVL
                     EKQLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIK
                     AETSQQAQLIQDSIVAINQQINSLSQQISDYEELRSAIINQSDSLSSNNPHQATLDAY
                     LSQSQANQETATNQLLFQIDQNLLNLKTSIDSLYRQRANLHQSTSYDNSLNTKLEILR
                     TQFLITASQQLTDVNHHITELKAQLEQATLQVNNLVIKASKSGIVQLNSAFEGKISIP
                     IGHDIAYIYPSLKQTKQALLTYYVSSESVSLLKKNQVVRLALDRHGNQPIVITGTIKT
                     IDELATKTKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKV
                     TE"
     gene            complement(3906..6062)
                     /locus_tag="TV193_001575"
     CDS             complement(3906..6062)
                     /locus_tag="TV193_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL1513752.1"
                     /translation="MTLFYKRTFVSQIDARDCGVAALASIARYYGSDYSLAHLRELAK
                     TNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVY
                     KSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
                     LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYI
                     LQQLMSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSI
                     IDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMN
                     HDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQ
                     ATLKQGAQLILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQ
                     AAKVANNRLNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTI
                     KQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQ
                     QAYVFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSG
                     GQKQRIALARALLTQAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIA
                     ERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE"
     gene            6322..6570
                     /locus_tag="TV193_001576"
     CDS             6322..6570
                     /locus_tag="TV193_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="HEL1513753.1"
                     /translation="MNMTLMKQFNIIDADKLAHIEGGGKGICKFVMSGSNGYACRYSN
                     GEWGYIVTKSNFEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            6577..6873
                     /locus_tag="TV193_001577"
     CDS             6577..6873
                     /locus_tag="TV193_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1513754.1"
                     /translation="MLTQEEILNKVYNLILDPTLTSEERVILVRFKDRVGESSNFDRE
                     VMMLSESLRQLAVKQIRVETMSVEMAKFYKEISTYKECDKQLGRGLISLGVIRR"
     gene            7615..7869
                     /locus_tag="TV193_001578"
     CDS             7615..7869
                     /locus_tag="TV193_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1513755.1"
                     /translation="MNTTLMKQFNIIDADKLAHIEGGKNNWQANVWEGGTAAVSGWGL
                     GTAICAASGAGAPFMGACGYIGAKFGVSLWAGVTGATGGF"
     gene            7886..>8083
                     /locus_tag="TV193_001579"
     CDS             7886..>8083
                     /locus_tag="TV193_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin BlpN"
                     /protein_id="HEL1513756.1"
                     /translation="MTHYYQIKEEELNDICGGNPAGAAVVGGLTCAVGGIKLGSRIGP
                     WGAVIGGVGSAAVCGYLAYKAS"
BASE COUNT         2334 a         1251 c         1804 g         2694 t
ORIGIN      
        1 gttgttttta atggatttat ttttgttatt gtgcttatta ttttgttgaa acggtagtag
       61 tgctaatgct tctgcagatt ggatagggga ctgagtttag gtgagagtag ttattttaga
      121 agatgatatg attcagcaga gatatttaga aaagctcatt aaagagcttg aggttaagca
      181 ccagctatta tttcaaggac ttgactgttt tggaaggcct catcagctat taagtgctat
      241 caagaagaac tgtggtcagc agctattctt tttagatatt gagataaaaa atgagaacaa
      301 aaaagggctt gaggttgcta ggcaaattcg tcagataaat ccagatgcga tgattgtttt
      361 tgtaacgact cactcggaat ttatgccctt ggcttttcag tatcaggtat ctgctttgga
      421 ctatatcgat aaagagctgc ctcaaactga gtttgttcaa cgggtagaga ctgctttatt
      481 atatgctgtg cggcaaaata gtgaaacgat agcggaaagt gctttttatt ttacatctcg
      541 ttatgctcag gtacaggtgc cttttaatga tatcctgtat attgagacat cgtcacgagc
      601 gcatcgtgtc aatttgtata caaaaaagga gagaatgcaa tttacgggga ctttgacgga
      661 tattttgaag caagagtctc gttttttgca atgtcatcgt tcttttttga ttaatcatag
      721 gaatgtcgtt agggtagata agattgagcg agtggtttat tttcgaaatg gctctagctg
      781 cttaattgct cgtagtaaaa tgaacagtgt tttaacaaca attgagaacc tacatagagg
      841 agataattaa tgaagcttat tttatttttc ttagaaatga cgacaagtat aggcttatcg
      901 ttagtgctct tttccaaaat cagtggacgt caattaacct ggcttgaagt tgctttcagt
      961 acttttttaa gaataggatt tgctgttttt ttcactatag ctaatcatgt tgccgacatt
     1021 tcacttctca attattggag tcttccaatt tatatggtag tgatatcatg gctattgctg
     1081 cgacccttat caaaaacatt attgatattt tatgggctat ttcctattac cctgtggagc
     1141 ctttggtacc gactgcttgg tttttttatc ttacctcttt ttaaacttga ttatcattta
     1201 acaaatgatg gattttgggg aatttttaca gatatagtat ctactttgat ggtttttctc
     1261 tttttgcggt ggctacgata tgatttcaga gcattaagaa ttaatctttt atctgatagg
     1321 gataaaagaa ttttaggtgt gaccaactgg tctatggtta gctattattt tttgatccaa
     1381 ttgcttgctt atttagagta tgagctagct gttgatactt atgcctatcg tcaatgcatg
     1441 atgcttggct attggattat atttatggga actgtgtcga gactggaccg gtcgctaaga
     1501 gatacactgc aagaaagact gacctttcaa agagagctgc agctggcaaa tattgagagc
     1561 tatagtcgtc agatagagga gctttacaga gaggttcgag gatttcgtca tgactatagc
     1621 aatctgattg ccacgttaaa gtttggtata gataatgata gcatgtctat tgttaggtca
     1681 gtttatcaat cggtctttaa ggattcaaat aaacgatttc gcaagcaaaa atatgatgtt
     1741 gggcgtctta tccatgtcac tgacacagcc ttgaaaagtc ttttagctgc aaaatttagt
     1801 caggctttag aaagtgggat ttcagtatct ttagaggttc cagaggatat cagtccgcaa
     1861 ggcatggagc tgattgattt tcttactatt gtgtctattt tatgtgataa tgctatagag
     1921 gctgctgttg aagcttcttc gtctaagata acgatttctt actttacttt ggacaataag
     1981 caactattta tgattgaaaa tacaactaag gaagagaaga ttgatctatc ctttctatat
     2041 gatttcggag taagcaccaa gggggataat agaggtgtgg gactttataa tgctatggaa
     2101 attatcaatc gttatcccaa tgtgatgatt aagactataa gtcaaaatca tgtatttggt
     2161 caaacacttg agcttaggtt ataaaaaaac accactagta aaggaaaact gtcttgcacc
     2221 tatcagattt gatgtttagg atcacatcat tccgatagtg tctcagtacc tttaggtagt
     2281 ggtgttttga aaatggagaa tgttactatt ttagtagttt tggcttagag acattgaaaa
     2341 ctttttgaag accttcaagc cagcctcctc cagtaatctg agttaactga gaaggcgtta
     2401 gttcctgaaa ctttggttgt ctagttggtt tatccatatt gaaagctcct tttaaatact
     2461 gtctatgtta ttatagctta tcttgactct ttgttgtact ctatgtccta aatggtcgtt
     2521 gaaaagcgct aaatggttat tctgtcactt taaagagctt gtccttataa aagtcaaaga
     2581 atgttttttt ggcaataaca cttatcactc gtccctgctg accatattga atagtagtgc
     2641 tttctttttc agaaagtgtt agtttggctg taaccttaaa aagatttccc tgcttggttt
     2701 tggtcgctag ctcatcaatg gttttaatgg ttcccgtaat gactatcggt tgatttccat
     2761 gtctatctag agctagcctg acaacctggt tcttcttaag gagagaaaca gattcagagc
     2821 tgacatagta agtgagcaag gcttgttttg tttgtttgag gctaggataa atgtaggcaa
     2881 tatcgtgacc gattgggata ctaattttgc cttcaaaagc actattgagc tgaacaatgc
     2941 cactttttga ggctttgatc accagattgt ttacctgaag agtggcttgc tccaattgcg
     3001 ccttgagctc agtaatatga tgattgacat ctgttaactg ctgagaggct gttatcaaaa
     3061 actgtgttcg gagtatttct agctttgtgt tgaggctatt atcatagctg gtagattgat
     3121 gtagattagc acgttgccta tagaggctat ctatagaggt ttttaggttt aaaagatttt
     3181 ggtctatttg aaatagaagc tgattggtgg cagtctcttg gtttgcttga gattgagaga
     3241 gataggcatc aagggtggct tgatgtgggt tattggagga tagactatcg gattggttaa
     3301 tgatcgcaga tcgaagctct tcatagtctg atatttgttg agaaagacta tttatttgct
     3361 gattgatagc aacaatagag tcctgaatca gctgggcctg ctggctggtc tctgccttta
     3421 tttttgagaa accaaggtca atatcttggg cttggctcat gaaatgatta aaggtattga
     3481 cgtaaccaaa ttgatcatcg ttctgaaaaa ggttctggcc ttgttttaag cttaacaata
     3541 gagtattaag gctgcttttt tgcttttcgt aggtagctaa ttgtttctca agtacctgct
     3601 tttgagactc ttctaggtct ttagcatatt gaataataga gtctccttgt ttgattggct
     3661 ggttattggt gagatggttc gcaattatag gattattgct aatagattgg actgttgcaa
     3721 tgacttgagt gggagtgatt tctccgtagg acgttaccgt tatttcttta taaacaaagc
     3781 aagaaaaaag gataagaaaa gtcaacaaga gggctaaggg aattgttaag aatgttgtca
     3841 aatgatgata gcgtctttgg tagaattccg cacttttaaa catattggga ttcatgattg
     3901 tctccttatt cactaaatag gtggtaataa aatccacctt gtttcattaa ttcctggtgg
     3961 ctgcctgttt caatgatttg cccttgatta agaacaacaa tctgatcagt gcgctctgcg
     4021 atactaagcc ggtgggcaac gaaaataatc gttttgtctg tcatgttcat gagacggtca
     4081 atgattttct tttctgtcag tatgtcaagt ccgctggttg cttcatcaag aactagtata
     4141 ggagcttggg ttagtaatgc tctagcaagt gcaattctct gtttttgtcc gccagataag
     4201 ccagccccat cagagagctc ggtttggtat cccattggca tttgctcgat gtcgtgacga
     4261 atgtcagcaa tctcacaggc gttaagaatg tcttcctggc tgatgccttg cttggctccc
     4321 aaggttagat tttctaagat agatccatta aacacatagg cttgttgtgg aaggtagttg
     4381 atgtattgtc gaagattctt tttatcaatg gtcttgagat cgttttggtt gatggttata
     4441 cgtcctttat aaggttcaaa gaaattgacg agcatcttgg ctagggttgt ttttcctgag
     4501 ccgctgacac caacaagggt tacttttgct ccctgcttaa tggttaatgt aatatctgat
     4561 aatgtatcct tgccaaagcc atacctgtag gaaacagctt caaactgaat gtcaccctgt
     4621 aagagcgata aatcgtataa ggcttgcgag gctttaaatt cggactctac aagatagacc
     4681 tcattgagac gattattggc aaccttagct gcttggagct tggtttgaag attaatgata
     4741 ttttctaaag gggttgtaaa ataggcaaga agtgtgttaa aggtaattaa ttgcccgatt
     4801 gaaattttac cattaatgac cagttgagcc ccaaaccaaa gaatgatgat attcagaatt
     4861 agctgcgctc cttgcttaag tgtggcttgt aagatggtat atttactaag cttaaaagac
     4921 ttatcaaggt aatccacaaa gtcgctgtca attttttggt aacggttttc ttcactggtt
     4981 agtgatttta tggtttcgat cccgttgata tcttcgataa tagcagagct tagcatggca
     5041 ttgctttgca tcacatcatg attcatttgt tcaaacggct ttataaaggc acatatgata
     5101 atggtatata ctgggataga aatcagagat agcagaaaaa gcctgctatt ttgcaccaaa
     5161 agaacacttc cgacaatagc taatatagag aggtctagaa agagggataa aatggttgaa
     5221 gcgagtgcat caataataga gttagcatct gtaaagcgcg aggttacctc acctgttcga
     5281 cgtgttgcaa aaaaggacat cggcaattcg aaaatatggc ggatatagga cagaatcaca
     5341 tcaatcgtaa gacgttggct aaggacagtt aaaagataat ctctagaaaa gctcattagc
     5401 tgctggagta tataggtaat gatgagacca attgatacaa tccctaaggt agatttcagc
     5461 tgatttggaa tatactcgtc taaaatcccc tggagatagt atgaaccagc aatattaatg
     5521 accgttacca agacagaagc taacacgata taaaatataa gggttcgctg tttaaaaata
     5581 agcggaaaga agcctaatag tccatttttt tggtctttat gtggtttata atttggctta
     5641 ggagcaagac atatggtgac acctgtccat tctgaagcaa agcgttcctt ggacattttt
     5701 gtgaccttga ccattggatc gggatcacca atgataagat agtctttttt agatttgtag
     5761 accacatagt agtgctgtag ctttccttct ttattgacat ggacgatcaa tggatagggc
     5821 acgtctgcca tgtcaaagag ggtcatatcc gcttgaatgg gtctggtttc aaatcccatt
     5881 tccttagcag ccatgacaat accgagggct gttgtccctt ccttattggt ttttgctaat
     5941 tctctcaaat gagctaatga ataatctgaa ccataatacc ttgcgattga ggctagagca
     6001 gctacgccac aatctctggc atctatttgt gatacaaagg ttcttttata aaagagtgtc
     6061 attggttggc ttcctttctc tgttgtaacg actctattgt gccacaaaag ctcagaaaaa
     6121 aactgagcta gtcttgaata gtcgttgaaa cgtcttaaat gggaataatg atattaacac
     6181 tcttttttaa tcagttgcga cattaccatt caagacgttt cgacgacatt ttaagactta
     6241 aatactgaaa gcagttattt atctgctata ctgggtttgt tgcttgcaac aggtaaaaaa
     6301 taaatatagg agatattcac gatgaatatg acattaatga aacaatttaa tattatagac
     6361 gctgacaagc ttgctcacat tgagggtggc ggcaaaggaa tttgtaagtt tgtaatgtct
     6421 ggttctaatg ggtatgcctg ccgatatagc aatggcgaat ggggctatat tgttactaaa
     6481 agtaattttg aagcaactaa agatgttatt gttaatggtt ggatatcctc tttaggaggt
     6541 ggttatttcc atccagggta tagagggtag ttgggtatgt tgacgcaaga agagatacta
     6601 aataaggttt ataatttaat tttagatcca accttaacat cagaagagcg agtcattctg
     6661 gtaagattta aagatagagt aggggagtca agtaactttg acagagaagt gatgatgcta
     6721 tctgaatctc tgcgtcaatt agctgttaag cagataagag ttgaaacaat gagtgtagaa
     6781 atggctaaat tctataaaga aatctctact tacaaagaat gtgataaaca gctaggtaga
     6841 ggcctaatat cattgggagt tattaggcga taataaaacg ctcatacctt atcgttgtat
     6901 tggcgttatt gttttgttga gtcacaatag gccaaatgac atgaaaaggt tgtcaatgct
     6961 attttgtgag atggctagct gaaggtaaag taagtaacga ttgagttgat tggctaatcg
     7021 caggatataa caatgggtat cagtttaaag ctgataccta ttgttttgtg gtagttaact
     7081 atctagggtg gtttcggaca agaagtagct tgagataatt gcaagggcaa taagcttatc
     7141 tcatttggtt agtgatttat tttttcttac aaagaactta tttttgagtc ttattgagct
     7201 tggaaaagaa atattatctg cgctattagc tatcaaatca gttgcttttc cttatttcta
     7261 gaggcttaag ttagtaagct gaggccacaa atgtattatt ttcatcagct gttgatgatg
     7321 tattgctatc tggaaaaata aaatagtcat ttaagattgg gctatttgtc attacagcat
     7381 agagccttca gccgtcaaag gaggaaactc agcttttgaa gcaattaaga cagctttctc
     7441 atatttgtta tgggtattag gaattttcac tgaattggtg ttaacggttt tcgtattacc
     7501 attcaagacg tttcgacgac attttaagac ttaaatactg aaagcgattg tttatctgct
     7561 atactgggtt tgtcagttgc agcagacaaa aaataaatat aggaggtatt cacgatgaat
     7621 acgacattaa tgaaacaatt taatattata gacgctgaca agcttgctca cattgaaggt
     7681 ggaaagaata attggcaagc taatgtttgg gaaggtggta ccgctgctgt tagtggctgg
     7741 gggttaggga cagctatttg tgctgcaagt ggtgccggtg ctccatttat gggagcatgt
     7801 ggttacattg gagccaaatt tggcgtatca ttgtgggcag gagtaacagg agcaacaggt
     7861 ggattttaat caagagaggt tttttatgac tcattattat caaatcaaag aagaagaact
     7921 taacgacatt tgtggaggga accctgccgg tgcagcagta gtaggtggtt tgacctgtgc
     7981 tgttggaggt ataaagttgg gaagtaggat tggaccttgg ggagctgtta tcggaggagt
     8041 tggaagtgca gctgtttgtg gttatttagc ctataaggct tca
//
LOCUS       DARYXS010000083         8014 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.084, whole genome shotgun sequence.
ACCESSION   DARYXS010000083 DARYXS010000000
VERSION     DARYXS010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8014
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.084"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            93..272
                     /locus_tag="TV193_001580"
     CDS             93..272
                     /locus_tag="TV193_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513757.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVASTVIM
                     SGIVCVLMNVSDIKE"
     gene            384..1580
                     /locus_tag="TV193_001581"
     CDS             384..1580
                     /locus_tag="TV193_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1513758.1"
                     /translation="MTFLDKIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVVGETDYKKACHAIKAAGYATASDYAELLIQLIEENNLQKWDKEALKTNKEVTMTTA
                     NEIVQYCVDLANSGMGVDKDGCFGTQCADLPCFIVKNWFGIDLWGNAIDLLNSAAAQG
                     LEVIYNAPGVNPKASDLFVMEVAGSPYGHTGAVIEDSDGYTIKTVEQNIDGNWDSLQV
                     GGPARFNTRDFTGVVGWIRLPVDHTNQTVDTAPQTSDTIVETSKTGTFTLDAAEINVR
                     RWPNLTSEVVDSYKQGQTVSFDSEGYANGYYWISYVGGSGKRNYMAIGPTDKDGNIIS
                     LWGKLN"
     gene            1865..2380
                     /locus_tag="TV193_001582"
     CDS             1865..2380
                     /locus_tag="TV193_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513759.1"
                     /translation="MKSKKLVFGQIDLNMCRDFDLVQALDYDFKEKKLYNKGRGFAIV
                     LVSIQNLTFAIPLRSNIPKKYQLKYKLRDSKKYGCVEGLDIGKALVVEDPKYILNRTF
                     KLREQVDYFKIVDNDILIVNKLIKAIIDYNQAVANSDQHKLTDPKRFKFSTFPNYTDR
                     LKSITDADYLR"
     gene            2576..2788
                     /locus_tag="TV193_001583"
     CDS             2576..2788
                     /locus_tag="TV193_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1513760.1"
                     /translation="MLTYDEFKQAVDDGYITGDTVAIVRKNGQIFDYVLPGEKVQPWE
                     VVTEEKVENVLRELDWRSVKSRSKLL"
     gene            3040..3243
                     /locus_tag="TV193_001584"
     CDS             3040..3243
                     /locus_tag="TV193_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEL1513761.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
     gene            3413..3874
                     /locus_tag="TV193_001585"
     CDS             3413..3874
                     /locus_tag="TV193_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEL1513762.1"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDCLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAVASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            3874..6315
                     /locus_tag="TV193_001586"
     CDS             3874..6315
                     /locus_tag="TV193_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1513763.1"
                     /translation="MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLA
                     AMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICQVIN
                     EHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
                     TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKE
                     VSRMVQVLCRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMS
                     VVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPA
                     LSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQY
                     HNVTISDTAVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQ
                     ALLDGDMSKVSALLVKEDKQPKLKPTAVTEDDMLHTLSKLSGIPLEKLTQADSKKYLN
                     LEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALA
                     ELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFD
                     EVEKAHPDIFNILLQVLDDGMLTDSRGCKVDFSNTIIIMTSNLGATALRDDKTVGFGA
                     KAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAA
                     LAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQS
                     LKIGVSRGKLAFDIA"
     gene            complement(6663..6749)
                     /locus_tag="TV193_001587"
     CDS             complement(6663..6749)
                     /locus_tag="TV193_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1513764.1"
                     /translation="MQLMLGFGSFLLSLIGLVVIIVKMSNKK"
     gene            7088..7519
                     /locus_tag="TV193_001588"
     CDS             7088..7519
                     /locus_tag="TV193_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513765.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKRTEEQQKKDLETSIAKL
                     LVHDYEDVKEVKFTGWGRSRETGSWGTIVVINGENEIGFSFDGLSGLADISGRSYHPD
                     TFKLVEKNSLEEMGPVKYRIKDIEKVSLEGVSITYSREKRS"
     gene            7521..>8014
                     /locus_tag="TV193_001589"
     CDS             7521..>8014
                     /locus_tag="TV193_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513766.1"
                     /translation="MMISDSSYKKLSEQVYNVEPSKAKSNDAPIVLKGNRLIDDKTGK
                     QYRVLLVQDNNNDAHKINDNGMQAMAVAPIVQGDVDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNLDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIV"
BASE COUNT         2454 a         1399 c         1860 g         2301 t
ORIGIN      
        1 gatcggcatg aggagcgttt aggacgtgta gaggacgaca ttattgtcaa taaagagcaa
       61 atcaaaacat tatttaaaaa aggagactaa aaatggataa atggtttaaa aaagtagcaa
      121 tcaaaacaat taagacaatg gcccaaaccg ctgtaggggt tattggatca agcgcattga
      181 ttactgacgt caactggcag gtggtggcct caacagttat tatgtcaggt attgtctgcg
      241 tcttgatgaa tgtgtctgac atcaaggaat agcattatgc gagcaatcac acgattagca
      301 atagtcatag caatcacaat actgtattta ccgctatctg tgattgctct gattgtttat
      361 ccgtttttag ataaggagga cagatgacct ttttagataa gattaagcaa ggctgcttag
      421 atggctggac caagtacaaa atcttgccat ctttaacagc agcacaggca atccttgaga
      481 gtggttgggg caagtacgcc ccacataacg ctctatttgg tatcaaggca gatagctctt
      541 ggacgggtaa gtcatttaat acaaaaactc aggaggagta tcagccgggt gttgtaacgg
      601 atattgtaga tcgttttagg gcctatgata gctgggacga gtcgatcctt gatcatggtc
      661 agtttttagt agataaccca cgatacaaat cagttgtcgg ggagactgac tataaaaagg
      721 cttgtcatgc aataaaagca gccggttatg ccactgcaag tgattatgcg gagctgctta
      781 tccagttgat tgaggaaaac aacttgcaaa aatgggataa ggaagcctta aaaactaata
      841 aggaggtaac gatgacaacc gcaaatgaga ttgtacaata ctgtgttgac cttgccaact
      901 caggtatggg agttgataaa gatggctgtt ttgggacgca gtgtgcggac ttgccatgtt
      961 ttatcgtcaa aaactggttc gggattgact tatgggggaa tgcgattgac ctgttaaaca
     1021 gtgcagcagc gcaaggtcta gaggttatct ataacgcacc tggagttaat ccaaaagcta
     1081 gtgacttatt tgtcatggag gtagctggca gtccttatgg acacacagga gctgttattg
     1141 aggacagtga tggctatacc attaaaactg ttgagcaaaa cattgacggc aactgggaca
     1201 gtttacaagt aggtggccct gctcgcttta atactcgtga ctttactggc gttgtcggct
     1261 ggattaggtt acctgttgac catactaacc agacagtaga tacagcaccg caaacgtctg
     1321 acaccatcgt ggagacgtca aaaacgggta cttttacact tgacgccgca gagatcaacg
     1381 tccgccgctg gccgaattta accagtgagg tagtagatag ttataagcaa ggccaaaccg
     1441 ttagctttga tagtgagggt tacgccaatg gctactactg gattagctat gtcggaggct
     1501 caggtaagcg taattatatg gcaattggtc ctactgacaa agacgggaat attatcagtc
     1561 tttggggtaa attaaattag gaggtaaaga tccgagataa gacaaaaccg ctctcttaat
     1621 cgagggcggt tttttgtgtc ttaaagattc tatatttgac gaatgcaaca tattatgtaa
     1681 taatgtaaat gaacataaat agtaaaagca ttatctctat gttccgacct ttccatgtcg
     1741 ttaaactctc gccattttgg caatgagggg gcggagggac gcgctcgtta acagaagtat
     1801 cccgttggca atgcgtccta ccaataccca gttggtagga ttttttattt ttagaaggca
     1861 aataatgaag agtaaaaaat tagtattcgg tcagattgat ttaaacatgt gtcgagattt
     1921 cgatttggta caagctttag actatgattt taaagagaag aagctatata acaaaggccg
     1981 aggttttgcc attgtgttgg taagtatcca aaatctaact tttgcaatcc ctttgagaag
     2041 taatattcct aaaaaatatc aactaaaata taaattaaga gactctaaaa aatacggatg
     2101 cgtagagggg cttgatattg gcaaagctct agtggttgaa gatccaaaat atattttaaa
     2161 cagaacgttc aaattacgag agcaggttga ttattttaag attgttgata atgatatact
     2221 tattgttaac aagttgataa aggctatcat agattataat caagctgtag ctaatagtga
     2281 tcaacataaa ttaacagatc ctaaacgttt caaattctct acattcccaa actataccga
     2341 cagattaaaa agcattaccg atgccgatta tcttcgttga caccctcgca caatcatgaa
     2401 ccaattacca tagtaagaat tagccaaaat aaaaatcaac cgctcagatt atttctgggc
     2461 ggttttttgt gtttcacaca catgtattca cacattggca tatccgttat aacggacttg
     2521 ttaaaattag tccattaaac tagacttttt acgaataata aggtaggagg tatttatgtt
     2581 aacatacgac gagtttaagc aagcagtcga tgacggatat ataacaggag acacagtagc
     2641 gattgtgcgt aaaaacggac agatatttga ttatgtgttg ccaggggaga aagtgcagcc
     2701 ttgggaagtg gtgaccgagg aaaaagtaga aaatgtgctg agggagttag attggcggtc
     2761 ggtcaaaagt cggtcaaagt tactctaaag cactgatatc aatgcatcta aaatccgtct
     2821 accgccttag attgttaaag caaggtcagc atgactttgc ttttttacat tttagcaggt
     2881 ggagtagaaa agctgtcatt gtgaggggta tgtgttgaca gtggctgcca ttcgtgttac
     2941 actgagcgag taaattagtt tttgaattag tagttgtgtt ttggcatctt tatttctctc
     3001 tatgtttaca aatgcgttat agaaaggaag tggatgacta tggcacaagg tacagtcaag
     3061 tggtttaatg ctgaaaaggg ctttggcttt atttcaactg aaaatggtca agatgttttt
     3121 gcacattttt cagcaatcca gtctgacggc tttagatcgt tagacgaggg acaaagggtg
     3181 acgtttgatg ttgaagacgg acagcgcggt cctcaggcag taaatatcac taaattgtct
     3241 taatctagtg agcagataat aggggatggg tgttgttgat agcacctgtc cttttacatt
     3301 ctagtgattt ccatttgctt ttagtgactg ctatttgata taatgttagt cagttttagt
     3361 caaataaagg cttaaagcag caaatgaatc gttttagcaa aggagtgacg gcatgccaac
     3421 aaaaaatact tccgatagta tcgaagaata tatcaaagaa ttgttagccc aatcaggaat
     3481 cgcagagatc aagcgctcca tgctggcgga ttcctttcaa gtagtaccaa gccagattaa
     3541 ttatgtgatc aagacccgtt ttacagaaag cagaggctat gaggtagaaa gtaagcgtgg
     3601 tggtggtggc tacattcgta ttgctaaggt tcatttttcg gataagcacc acctgattgg
     3661 tacgttgatc gcttctattg atgattgttt aagcgagcag gcctttacag attcgattca
     3721 gctgcttttt gatgagcaac tgttaacaga gcgcgaagga aacattatct tagctgtagc
     3781 ttctaatgat gttttgggac atcaagcacc agaaattcgt gctcgtatgc tttatcgcct
     3841 attgcaacga attgatagaa agggaagcaa ttagtgatga tttattcatt aaagatgcaa
     3901 gacattttta atcaggctca atttcaagca gagcgctttg atagtcctta ccttgagacc
     3961 tggcatattt tattagctat ggtagctgtt gaccattcct tagcggccat ggtgttaagc
     4021 gaatttgaac gaaagattag ggctgaagag tatgaggctg ctgctatttt agccatggga
     4081 aaaagtccca aagaggtgac ttctgtccaa ttcaagccac aatccaaggc cttatcagaa
     4141 atactagcat ttgctcatgc tatctgtcag gttatcaatg agcatgaggt tggctcagag
     4201 catgtactct ttgctatttt gctcaatccg gatattatgg ccagtcgtct gttagaattg
     4261 gcaggctaca ggctcaagga ttctggcaag ggagagccta ggtttgcgga tttacgtaag
     4321 gctattgagc taaatgccgg ctatagcaag gaaactatta aggcgattca tgagttgcgt
     4381 aagcctaaaa agagtaaatc agtaggcacc ttttctgaaa tgatgaagcc acagagtaca
     4441 gctggtgagc tatcagactt tacaagagac ctgacagaga tggcaagaca gggcttatta
     4501 gagccagtca tcggacgaga aaaagaggtg tcacgtatgg ttcaggtgct ttgtcgtaag
     4561 acgaaaaata atcctgttct tgttggtgat gcgggtgtcg gaaaaactgc tctagcttat
     4621 ggcttagcgc agcgaattgc taatggagcc attccttatg aattacaaga catgcgtgtc
     4681 ttggagcttg acatgatgag tgtggttgca ggtacccgtt ttcgtgggga ttttgaagag
     4741 cgcatgaatc aactcattga cgatattgaa gcagatggta agatcatttt gtttgtcgat
     4801 gagctacata ccattatggg atcaggaagt ggtattgaca gcacacttga tgccgctaat
     4861 attctaaagc cagccctttc tcgcggtacc ctgcatatgg ttggcgctac aactcaagag
     4921 gaatatcaaa agcacattga aaaggacgca gccctttctc gtcgctttgc caagatattg
     4981 attgaggagc ctagtgttga ggacgcttat cagattttgc ttggcttgaa gccttcctat
     5041 gaacagtacc ataatgtaac aatctctgat acagctgtcc atactgctgt gaagctggct
     5101 cggcgctatt tgacaagtaa gcagcttcca gactcagcga ttgatctgct tgatgaagcc
     5161 agtgcgatgg tgcaaagtat ggttaaaaag acgcagcctg actttataac accgcttgat
     5221 caagccctgc ttgatggtga tatgagcaag gtgtcagccc ttttagtcaa agaggataag
     5281 caaccaaagc taaaaccaac agcagttact gaagatgata tgttacacac cttaagcaag
     5341 ctatcaggta ttcccctaga aaaactaact caggcggata gtaaaaaata cctgaatctg
     5401 gaaaaggaat tgcataagcg tgttgttggt caggaaatgg ctgtttctgc tattgcacga
     5461 gccattcgtc gtaaccagtc aggcattcgc acaggcaggc gtccgattgg ctcctttatg
     5521 tttcttggtc caactggtgt cggaaaaaca gagctagcaa aggccttggc cgaattactc
     5581 tttgatgatg agtcagccct tattcgtttt gatatgtctg agtacatgga aaaatttgca
     5641 gcctcccgtc ttaatggggc tcctcctggc tatgttggct atgatgaggg aggagagcta
     5701 accgaaaagg ttagaaataa gccttatgcc gttcttcttt ttgatgaggt tgaaaaggct
     5761 cacccagaca tctttaatat cctgctgcag gtccttgatg atggtatgtt aacagatagt
     5821 cgtggatgta aggttgattt ttcaaacacg attattatca tgacgagcaa cctaggagca
     5881 actgctctaa gagatgataa gacggttgga tttggcgcta aagcgatcgg tcatgaccat
     5941 caagcaatgg aaaagcgtat tttagaggaa ttgaaaaagg cttatcggcc tgaatttatc
     6001 aacagaattg atgaaaaggt ggtcttccat agcctaacac aggaaaacat gcgtgatgtg
     6061 gtgaaaatta tggttaagcc gctgattgca gccttggcag aaaagcatat tagccttaag
     6121 ttccagccat cagctctcaa gtacttgtct gaagctggtt acgatgttga aatgggcgct
     6181 cgcccacttc gtcgcacctt gcaaacagag gttgaggaca ggttagcaga attaatgctg
     6241 tcaggagagt tatcaagcgg tcaaagcctc aagattggtg tatcacgtgg aaaactagct
     6301 tttgatatcg cttaatgcat gactttgctt gatattaagc taagagcttt gagagagtct
     6361 gagacaaaaa gtttctcagg ctctttttgt cgtatggtga tgaagtacta gagtgagagt
     6421 ttaaagcgta gcagacagat aggatttaat tttaatcgaa tttagcgaaa aataggtatt
     6481 ttgaagattt agctaccaat ttagctgcca aaatagtatc tcatttgact atttttctta
     6541 gctgagatat aatgaaaata gaaaaaggac agttgctcaa aacaactacc caatgcagaa
     6601 ccgtttaaga cggtagcttg tttttagtta aaaaataacc gttactcgct aaagttagac
     6661 ggttattttt tattgctcat ttttacgata ataacaacta agccaatgag tgaaagtaga
     6721 aaactaccga acccaagcat gagttgcatt gcctcgtaaa cggacaatat tcgctccttt
     6781 ctctttggat tttagcactt acagtcataa gcaccaccac ctttcagaaa ttagagccac
     6841 cgccttaact tttctgcaga aaccattata ccatagtcat acgaaatagc tgtctgatgt
     6901 tgaaaattca gatggctttt ttgtgtcctt tgcttgcagg gaagaaatat accctaaaat
     6961 cgtttttaag cgattgtttg ttgagatggt atatttttta tcgaatacga cataaaaatt
     7021 gaatatggtt attctatgac ttctgattta ttgtatacta ttattagaaa ttgaaaggag
     7081 aactttcatg aaaaagtcga ccaaagcttt tattgcttta atgattctaa taggagggct
     7141 gcttatggtt tttagtttga atggcaaaag aacagaggaa caacaaaaaa aggatttaga
     7201 aactagtatt gctaaactgc tggttcatga ctatgaagat gtcaaagaag ttaagtttac
     7261 aggctgggga cgttctcggg aaacaggttc gtggggaacg atagtagtta taaatggaga
     7321 aaatgaaata ggcttttcgt ttgatggttt gtcaggatta gcggatatta gtgggcgctc
     7381 ttatcatcca gatactttta agttagttga gaaaaatagt ctggaagaaa tggggcctgt
     7441 gaaatataga attaaagaca ttgaaaaagt ttctttagag ggagtgtcaa ttacgtattc
     7501 tcgtgagaaa aggagttaat atgatgatat ccgatagtag ttataagaag ttgtcagaac
     7561 aggtctataa tgtcgaacct agtaaagcta agtcaaatga tgcccctatt gttttaaagg
     7621 gaaatcgtct tatcgatgat aagacgggta agcaataccg agtcctctta gttcaggata
     7681 ataacaacga tgcccataaa atcaatgaca acggtatgca agcaatggct gtagccccta
     7741 ttgttcaagg tgatgtcgat acctcccagg ttgtgattgc ctatgcaggg acaaatgctg
     7801 cggattccag agatcttgat acggattggc agctgctcat tcggggcaat caagatgatt
     7861 tagtcagcgg caatcttgat ggcggcaatt ttgttattgc cgaaaaccaa ttacgatctg
     7921 ctcaaaagtt ttatcaacaa gtcaaaagaa agtaccctca ttctgcctta acaaccacag
     7981 gtcactctct cggagcttat ctagcactaa tagt
//
LOCUS       DARYXS010000084         7904 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.085, whole genome shotgun sequence.
ACCESSION   DARYXS010000084 DARYXS010000000
VERSION     DARYXS010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7904
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.085"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            521..1114
                     /locus_tag="TV193_001590"
     CDS             521..1114
                     /locus_tag="TV193_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEL1513767.1"
                     /translation="MIIKKLSVIALTSLSLISLSACRQQNQALGQNGSAQNHRKASVS
                     EDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEFDAKDQEYSYTIDANTGEIL
                     EKSSEPITEAPASAQAAGGQADQAAGISEDKAKELAFKDASITAADAQRLKLTKETDD
                     GRVVYDIEFDAKDQEYSYTIDANSGDILEKSSEPVYD"
     gene            1454..2959
                     /gene="glpK"
                     /locus_tag="TV193_001591"
     CDS             1454..2959
                     /gene="glpK"
                     /locus_tag="TV193_001591"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEL1513768.1"
                     /translation="MGTETYIMAIDQGTTSSRAIIFNKKGEALVSSQKEFPQLFPQAG
                     WVEHNANHIWNLVQSVIADAFIESGIKPEQIEAIGITNQRETTVVWDKQTGLPIYNAI
                     VWQSRQTASIAEQLKRDGYTKMIHEKTGLVIDAYFSATKLRWLLDHVPGAQERAERGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILALLNIPKAMLPEV
                     RSNSEIYGKTASFHFYGGEVAIAGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GQEAQLSSSNLLTTIGYGINGKVYYALEGSIFIAGSAVQWLRDGLRMIKTSFESEQLA
                     LASTNADEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTTKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGITIQQLRVDGGAAMNNMLMQFQADILGIDIARAENLETTALGAAFLAGL
                     AVGYWKDMETLKQLNATGQLFKASMSESRREKLYQGWKRAVKATQFFAEEL"
     gene            3133..3777
                     /gene="fsa"
                     /locus_tag="TV193_001592"
     CDS             3133..3777
                     /gene="fsa"
                     /locus_tag="TV193_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1513769.1"
                     /translation="MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIK
                     EICEIVDGPISAEVTGLTAEEMIAEARNIAKWHDNVVVKIPMTTEGLKATNVLSQEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEI
                     IAASIRTAAHVEAVAQLGGHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK"
     gene            4161..6149
                     /gene="tkt"
                     /locus_tag="TV193_001593"
     CDS             4161..6149
                     /gene="tkt"
                     /locus_tag="TV193_001593"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1513770.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHVMTVNPKTSRRWSNRDRFILSAGHGSAMLYSLLHLAGYDVSIEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGVANAVGMAMAEAHLAAKFNRPGFDIVDHYTYALNGDG
                     DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEAIAKAIEEAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKSYQWTHADFEVPQEVTERFRQGLQARGEQAEQAWNDLFAAYEAAYPELAAEYKKAF
                     ANEAAEVELQAHELGTAVASRVSSQQAIQQISEQVPAFWGGSADLSASNNTMVKAETD
                     FQPGHYAGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQQ
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QAALAADGIHVRVVSMPSQNIFDEQPASYKEEILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVEHATELYKSLS"
     gene            complement(6331..7806)
                     /locus_tag="TV193_001594"
     CDS             complement(6331..7806)
                     /locus_tag="TV193_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1513771.1"
                     /translation="MINKRKKKLIYRYGVCSAAVILAALASLGTCKEAKALSGPPGYP
                     LTRDFSRNFLEENTAKYLDQLREHLQHRFSELESLTRKLEKEGGTRGPAGPPGPAGPK
                     GERGEPGPVGPMGPRGEQGPKGLDGARGPEGQQGKPGPVGPQGPAGPAGQKGETGPQG
                     PRGDKGDTGETGKQGPAGERGPAGPQGPRGDKGENGAPGEQGPIGPKGETGPKGDKGE
                     RGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGQRGEKGEQGPRGEK
                     GEQGPRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGPRGEKGEQG
                     PRGEKGEQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGE
                     NGEQQPKGDQGKDTKPSVPKAPESPKMPEKPQAPEKAPAPKAPKASEQSASPKAPAPQ
                     STPSKKAVLPATGEASHPFFSLAALSVIASAGLLTLKRKKS"
BASE COUNT         2005 a         1707 c         1937 g         2255 t
ORIGIN      
        1 atatcccttg tgaccttact atgtttttta gctatttata tagaaaaaag gtaaattaag
       61 ttttgtatgg ttcgtttaga tactttttca acagtttagg gagtatttgt aatcaatcag
      121 aaatgctggt aaatgctgaa ggtcggctat ggatacgcac tggaggtgta agaaacatcg
      181 atgctggtac ttaaaagtag cttggtgtca gatagtgagt ggcagtgagg gttcatacca
      241 aaatggtcat taaatagtga ttgatagctg gtgaaggcaa taaataagac caaaataatt
      301 cttctcattc taccaataat tgcttttttt attcggctgg gtgatctatt cttggttgag
      361 ggatagcaaa gtccttacct ttaccttatg ggctctttgg gggttatcat ataagggagt
      421 aagcctggtt aagagagttt tagcgcttta aaattgtaaa atcagattat ttaatgtata
      481 ctagaggaaa taagatgaat aaagacggaa ggtcaataca atgataatca aaaaactttc
      541 agtaatagct cttacgagtc tatccttaat cagcctatca gcttgtcgtc aacagaatca
      601 ggctctaggt caaaatggca gtgctcagaa tcataggaag gcaagtgttt cagaggacaa
      661 ggccaaggaa cttgccttta aggacgcctc aatcacagca gctgacgctc aaaggctcaa
      721 gctgacgaaa gaaacagacg atggtagagt ggtctatgat attgagtttg atgctaagga
      781 tcaggagtat agctatacca ttgacgctaa taccggtgag atcctagaaa aatcctctga
      841 gccaatcact gaggctcctg cttcagctca agcagctggt ggtcaggctg atcaagcagc
      901 tggcatttca gaggacaagg ccaaggagct tgcttttaag gacgcctcaa tcacagcagc
      961 tgacgcccaa aggctaaagc tgacgaaaga aacagacgac ggtagggtgg tctacgatat
     1021 tgagtttgac gccaaggatc aggagtacag ctatactatt gatgctaata gtggagatat
     1081 tttagaaaag tcctctgagc ctgtttacga ttaaaaagct atcaccgctt atgtgataaa
     1141 agcctgtaac attcctaagc ctttatatgc taaaagggct taggtttttt gttgttcctt
     1201 gttgtgcctg atagagctgg agcttgttgg cagccattta ggcgctagcc tatagcccgc
     1261 ctttgttgct ggtatttggc tgtgataagg gctgtttagt tgaaatgata ggcattatca
     1321 gcttaggatt tggcagagtg atacttttat gactagaagg ataggctatg ggctgtaaat
     1381 gttgtataat agagtagaaa gcgcttgcta tgattgagag agcctatctc agcagcgata
     1441 gaatggagga cacatgggaa ctgaaaccta tattatggct attgatcagg gcacaacgag
     1501 ctctcgtgcc attattttca ataagaaagg agaagcgctg gttagtagtc aaaaggaatt
     1561 tccacagctt tttccacagg ctggctgggt tgagcacaac gccaatcaca tttggaattt
     1621 ggtgcagtct gttattgcag acgcctttat cgagtctggt ataaagccag agcaaataga
     1681 agctataggc attaccaacc agcgtgaaac aacggtagtc tgggacaaac agacaggtct
     1741 gcccatctat aatgctattg tgtggcaatc tagacaaaca gcctccattg cagagcagct
     1801 aaagcgtgat ggctatacca aaatgatcca tgaaaaaaca ggcctggtta tagatgctta
     1861 tttttctgcg accaagctca gatggcttct tgatcatgtt ccgggggctc aagagcgagc
     1921 tgaaagggga gaattattat ttggcacgat tgacacctgg ctggtttgga agctaacgga
     1981 cggggcggta catgtgacgg attattctaa tgcagcacgt accatgctat acaatatcaa
     2041 agagctaaaa tgggacgatg agatattggc cttgctgaat atccctaagg ccatgcttcc
     2101 tgaggtcagg tctaattcgg aaatttatgg taaaacggct tcttttcatt tttacggagg
     2161 agaggtagct attgctggca tggcaggtga tcagcaggca gccctatttg ggcaactggc
     2221 ctttgagcct ggtatggtaa aaaataccta tggcacaggc tcttttatca tcatgaatac
     2281 tggtcaagag gctcaattat ccagcagcaa cctgctaaca acgattggat atggtattaa
     2341 tggcaaggtt tattatgcct tagaagggtc tatctttatt gctggctctg ctgtgcaatg
     2401 gctacgagat ggcttgcgaa tgataaaaac ctcttttgag tctgaacagc tagccttggc
     2461 ttcaaccaat gctgatgagg tatatgttgt accagccttt acaggtcttg gcgctcctta
     2521 ttgggattcc aatgcacgcg gctcagtatt tggcttaacg cgtggaacaa caaaagagga
     2581 ttttgttaag gctaccctac agtctattgc ttatcaggtc agagatgtga ttgataccat
     2641 gcaggtggac tcagggatca ctatccagca attacgtgtt gatggcggag cggctatgaa
     2701 taacatgctc atgcagtttc aggcagatat tttagggatt gatattgctc gtgctgaaaa
     2761 tcttgaaacc acagctctag gagcagcctt tttagccggg cttgctgtag gctactggaa
     2821 ggacatggag acgctaaagc aattaaatgc tacaggtcag ctgtttaaag caagcatgag
     2881 tgagtctcgc cgagaaaagt tatatcaagg ctggaaaaga gctgtcaaag ccacacagtt
     2941 ttttgcagag gagctgtaag aatcaagcct tttaaagaaa cagagtccca tagctaggtc
     3001 tagttttgaa cactagactg tgtgatactt ggtcttttat atcctaagag tgacttttat
     3061 aatgataatg tagacggtaa acagcgtcat gctgttcaat gactgataac agactaatta
     3121 acggaggtta agatgaaatt tttcttagac acagcaaatg tagaggcaat tcgtgcgatt
     3181 aatgagcttg gtgttgtgga cggtgttacc acaaacccta gcattatctc gcgtgagggt
     3241 cgtgattttg agacagttat caaggaaatc tgtgagattg tggacggccc tatcagtgca
     3301 gaggtcaccg gactaaccgc agaggaaatg attgcagagg ctaggaacat tgccaagtgg
     3361 catgacaatg tggtcgtgaa aattccgatg acgacagagg gcttaaaagc aactaatgtc
     3421 ttgtcacaag aaggcatcaa aacaaatgtg acgcttattt ttacagttag tcagggacta
     3481 atggccatga aggctggtgc gacctatatc agtccattta ttggtcgctt agaggatatt
     3541 ggagcagatc cttatcagct tattagtgat ttgcgtggga tcattgattt gtatggcttc
     3601 caagcagaaa tcatcgcagc cagcattcgg acagctgccc atgttgaagc tgttgcacag
     3661 ctagggggac acattgcaac cattccagat ccattatttg cgaagatgac tgagcaccca
     3721 ttgacaacaa atggcttaaa gacctttatg gaggattggg cttcctttaa aaaataggct
     3781 aagagcatag agctctcctt atattctaat gtggctgtag cggttagttt gggattagct
     3841 atttgtaggt ggcaggatca gctggtgctt tgctgttgcg ctagaattaa caggcagctg
     3901 gcgcttactg tagccaaagg gaggtaccaa agaggaatgc ttgcttagct ggcaacagct
     3961 aggcttgctt tttcttatga gcataggtgc tctatctaag acagctgtca atcacaaaaa
     4021 gctaggaaca gcaatgctta ttgctagata agaatttaag gactttatag gattttgtta
     4081 aaaatcagtt tacttttatg ttacaataga caatggaaaa cgtttaattt ttagttgtaa
     4141 tacacagaga ggttttactt atgacatttg atgcaattga tcagctggca gttaatactg
     4201 ttcgtactct atcaatggac gctattcaag cagcaaattc tgggcatcca ggtttgccga
     4261 tgggggcggc gccgatggct tatgtgctat ggaatcatgt tatgacagtc aatccaaaga
     4321 caagccgccg ttggtcaaat agagaccgct ttatcctatc agcaggtcat ggtagtgcca
     4381 tgctttacag cctgttgcac ctagcaggct atgatgtgtc tattgaggat cttaagaact
     4441 tccgtcaatg gggctctaaa acaccaggtc acccagaggt caatcataca gatggcgttg
     4501 aggcaaccac agggccttta ggacaaggag ttgccaatgc agttggtatg gctatggcag
     4561 aggcacactt agcagctaag ttcaatagac ctggctttga tattgtagac cactatacct
     4621 atgctctaaa tggtgacgga gaccttatgg agggtgtcag tcaggaggca gccagtctgg
     4681 caggtcactt gaagcttggt aagcttgtct tgctatatga ttcaaacgat atttcgcttg
     4741 atggcccaac ctcaatggcc ttcacagaag acgtcaaggg gcgttttgaa gcttacggct
     4801 ggcagcatat ccttgttaaa gacggcaacg acctagaggc cattgctaaa gctatcgagg
     4861 aagctaaggc agagactgaa aagccaacca ttattgaagt aaagacaatc attggctttg
     4921 gtgctgaaaa gcaaggaact tcagctgttc atggggctcc gcttggtgca gaaggcattg
     4981 cctttgctaa gaaatcttat caatggaccc atgctgattt tgaggtgccg caagaggtga
     5041 ctgagcgctt tagacaaggc cttcaggcgc gtggtgagca ggctgagcag gcatggaatg
     5101 acctatttgc agcttatgaa gcagcatacc ctgagttagc agccgaatac aaaaaagcct
     5161 ttgctaatga ggcggcagag gttgagttgc aagctcacga gcttggcaca gcagtagcca
     5221 gtcgtgtttc tagccagcag gctatccaac aaatctctga gcaggtgcca gccttctggg
     5281 gaggctcagc tgacctttct gcctctaaca ataccatggt taaggctgag acagacttcc
     5341 agccgggtca ttatgctggt cgtaacatct ggtttggcgt acgcgaattt gcaatggcag
     5401 cagcgatgaa cggtattgcc cttcatggtg gaacacgtgt ttatggcgga accttctttg
     5461 tcttttcaaa ctacctattg ccagcggttc gtatggcagc cttgcagcag ctaccaacgg
     5521 tttatgtcat gacgcatgat tctatcgcgg ttggtgaaga tggtccgacc catgagccaa
     5581 tcgagcagct agctagtgtt cgatcaatgc caaatctgaa cgttattcgt ccagctgacg
     5641 gcaatgaaac aaacgctgct tggaagcgtg cgatcgctga gacagaccgt ccgacaatgc
     5701 ttgtcttaac acgtcaaaac cttcctgtac ttgaaggtac taaggaattg gcagaagatg
     5761 gccttaataa gggagcttat atcctgtcag aggcaaaggg tgaccttgat gggattatca
     5821 ttgcaaccgg ctctgaagtc aagctagcaa tggatactca agccgctctt gcagcagatg
     5881 gtatccatgt gcgtgtggta tcaatgccat cacaaaatat ctttgatgag cagccagctt
     5941 cctacaagga ggaaatccta ccagcagcag tgacaaaacg tctagctatt gaagcaggct
     6001 caagctttgg ctgggcaaaa tacgttggcc ttgcagggaa aacactgacc attgatacat
     6061 ggggagcttc tgcaccgggc aatcgtatct ttgaagaata tggctttaca gtagagcatg
     6121 ctactgaatt gtacaaatcc ttatcataag tgattaagct ggagcaggcc ttatctaggc
     6181 ttgctttcgg cattattaga caaaaaaacg catgatgttc aacccttttt agggaggacg
     6241 tcatgcgttt ttgtttcaga tttaatagtg ctactgctca gccttgcaga tctatcccga
     6301 gttgctagaa gctattgtca aatagctggc ttagcttttc tttcttttta gggttagcag
     6361 acctgcgcta gcgatgacgc taagagctgc cagactaaag aatggatggc ttgcctctcc
     6421 tgtagctggt aggactgctt ttttgcttgg tgttgactga ggtgctggtg ccttagggct
     6481 agctgactgc tctgaagcct ttggagcttt cggtgcagga gccttttcag gagcctgtgg
     6541 cttctctggc atttttggtg attctggtgc ctttggaact gatggcttgg tatcctttcc
     6601 ttggtcaccc tttggctgtt gctcaccatt ttcaccgcgt tgaccttgct cgcctttttc
     6661 gccacgttga ccttggtcgc ctttttcacc gcgttgacct tggtcgcctt tttcgccacg
     6721 ttgaccttgg tcgccttttt caccgcgctg accttggtcg cctttttcgc cgcgttgacc
     6781 ttgctcgcct ttttcaccgc gtggcccttg ctcgcctttt tcaccgcgtg gcccttgctc
     6841 gcccttttca ccacgttggc cttgctcgcc tttttcaccg cgttgacctt ggtcgccctt
     6901 ttcaccacgt tgaccttggt cgcctttttc gccgcgttga ccttggtcgc ctttttcacc
     6961 gcgtggccct tgctcgcctt tttcaccgcg tggcccttgc tcgccctttt caccacgttg
     7021 gccttgctcg cccttttcac cacgttggcc ttgctcgcct ttttcaccgc gttgaccttg
     7081 gtcgcccttt tcaccacgtt gaccttggtc gcccttttca ccacgttgac cttggtcgcc
     7141 cttttcgccg cgttctccct tgtcaccttt aggtccagtc tcaccttttg gaccaatagg
     7201 gccttgctca ccgggtgcac cgttttcacc cttgtctccg cgcggtccct gaggtccagc
     7261 tggcccacgt tctcctgctg gtccttgctt tccagtttct ccagtatcgc ccttatctcc
     7321 acgaggtccc tgaggtccgg tttccccttt ttgccccgct ggacctgccg gcccttgagg
     7381 tccgacaggt ccaggttttc cttgctgtcc ctcgggccca cgtgctccgt ctaagccttt
     7441 aggaccttgt tcacctctag gtcccatagg tccaacaggc cctggttcgc cacgttcccc
     7501 tttaggtccg gctggccccg gaggccctgc tggacctcgg gtaccgcctt ctttctctaa
     7561 ttttcttgtt aagctctcaa gttcactaaa tctgtgctgt agatgttctc ttaattgatc
     7621 taaatatttt gcagtatttt cttctaggaa gttacgggag aaatcacgag taagtgggta
     7681 tcctggcgga ccagataatg cttttgcttc tttacatgtt cctaggctag caagcgctgc
     7741 taggataact gctgccgagc agacaccata cctgtagata agttttttct ttcttttatt
     7801 tatcatttct ctctcctttg atgatagaaa tatgaagtat tcctaaaaat cttttccaat
     7861 agctatctta acacgctagc taaatgtaag aaatagctgc tgat
//
LOCUS       DARYXS010000085         7884 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.086, whole genome shotgun sequence.
ACCESSION   DARYXS010000085 DARYXS010000000
VERSION     DARYXS010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7884
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.086"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(1..234)
                     /locus_tag="TV193_001595"
     CDS             complement(1..234)
                     /locus_tag="TV193_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HEL1513772.1"
                     /translation="MVFDYSKLSGRIVEKFGTQYNFALALGLSERSLSLKLNNKVDWR
                     SKEIAQACQELDINENDVGEYFFKQNVHIHEQN"
     gene            403..1200
                     /locus_tag="TV193_001596"
     CDS             403..1200
                     /locus_tag="TV193_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1513773.1"
                     /translation="MQCSSTSNRLKQLMSERNLRQVDILEKSKPFQKQLGVKMGRSTL
                     SQYVSGKSVPAQRQLYLLSKTLNVSEAWLMGYDVAIERIPDEKRGATTEISNQPEIVS
                     IYNQLEQPRQEKVLDFAKEQLEEQKHEQNNLFEVTGISYAAAASGLGRGFDVDDYDTY
                     TVYTDEEPPRYDYAIGVRGDSMLPTYEAGDMLYLVDKGMSNYSGQLCVIAYNGQTYFK
                     KVYTEANGLRLVSLNKKYDDIFIDYPPAEDTYIKIFDVIGSFVPVEM"
     gene            1324..2769
                     /locus_tag="TV193_001597"
     CDS             1324..2769
                     /locus_tag="TV193_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1513774.1"
                     /translation="MFTTNKVAIYVRVSTTNQAEEGYSIEEQKDKLSSYCNIKDWSIY
                     NIYTDGGFSGSNTARPALENLIKDAKKKKFDTVLVYKLDRLSRSQKDTLYLIEEVFIK
                     NGIEFLSLQENFDTSTPFGKAMIGLLAVFAQLEREQIKERMQLGKLGRAKSGKPMMWS
                     KPAYGYIYHKESGELIVNELEAIVVREIFKSYLEGMSITKLRDKVNEKYPKTPAWHYR
                     IIRGILANPVYCGYNQYKGQVFPGNHEPIISEEVFNKTQEELKIRQQTAAEKFNPRPF
                     QAKYMLSGIAQCGYCHAPLTIIMGMIRKDGTRFIRYECKQRYPRKTKGVTVYNNNEKC
                     HSGAYEKSDIEEYVLKEISKLQNDKDYLDEIFSDSNTETIDRESYQKQIEELSKKLSK
                     LNDLYIDDRITLEDLKKKSYEFTSMRTLLETELENDPALKKQKRKDDMKKILSAEDIF
                     SMDYEGQKIMVRGLINKVQVTADDVFIKWKI"
     gene            complement(2850..3836)
                     /locus_tag="TV193_001598"
     CDS             complement(2850..3836)
                     /locus_tag="TV193_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEL1513775.1"
                     /translation="MKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYV
                     TSMEASLLKGNGLADMLAALGYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKR
                     KTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLLHLPHYFLGFCLLVLLL
                     IGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEM
                     MSNEKSQLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELD
                     IYSQESWETFFSQLNRATQWIQPIIFLVVAVVIVMIYAAILLPIYQQMGDVF"
     gene            complement(3817..4755)
                     /gene="tadA"
                     /locus_tag="TV193_001599"
     CDS             complement(3817..4755)
                     /gene="tadA"
                     /locus_tag="TV193_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEL1513776.1"
                     /translation="MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDDTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQ
                     KEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ"
     gene            complement(4937..5584)
                     /locus_tag="TV193_001600"
     CDS             complement(4937..5584)
                     /locus_tag="TV193_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513777.1"
                     /translation="MIRLEKVSKCFGDRVLFSDLSMTFESGKVYALIGSSGSGKTTLM
                     NMLAALEDYQGEIFFRGKNLKTYRSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKISKEEGRQRELEALRAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHKNRTIIIATHSPSIWEMADEVISVDQLSSLTRL"
     gene            complement(5586..7589)
                     /locus_tag="TV193_001601"
     CDS             complement(5586..7589)
                     /locus_tag="TV193_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEL1513778.1"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLADETDSLIAMQHQEPGPEGTPIVTYTLFGKGKLPGGLAEKVIEEP
                     SRLSVENNYFILKGGLTVERLRDTLAGLGMTKMTALKPSFLGTLVLIFSSGSQALGIV
                     IFCLTFGALTLIGHIRTLRAVGIRLISGERRWQIFLYPIRSDVCYCCLGLLLGLSLAA
                     IMSQLMSFSPLVLYLIGIGLVCYNLLLIAIALFFAGLFVIGIKRVHLMQVIKGQIPVR
                     GIISLILIAQLLAVLVVSFGASRTLLYVQAERQQKQGQAAWLQEDRLVTLLIGRDGLD
                     IGNTKEAIAKQKTWFHVMDQAVSEHGAILSRHYLVERDLQSGLSMLTASSSWNDYSPQ
                     GNVLLVTPQYVKHQKVEVAPDISEKINQLSLGEFVLLLPEHLKTQAAQYQSVFESAVT
                     GLASGEGHQPMTATVSYTKTGQERFLYNTTPISYQQFLRDPIIVVLTPKSTGEQAYAF
                     WEVALQNYFLFDQLADTQTLIKQNGIENWVGELKTGYRIYETLLNNLRREIWLMIAGA
                     ILGIATSMLMFNTMNLLYFEEFRRDIFIKRVSGLRFFELHRRYLLSQLLVFFVGLVIS
                     ALLTQNPLMCLLVFFLFLGNAILLLYRQMRIENKMSLLILKGA"
BASE COUNT         2578 a         1724 c         1463 g         2119 t
ORIGIN      
        1 ttagttttgt tcatgaatat gaacattttg cttaaaaaaa tattctccta catcgttttc
       61 gttgatatct aactcttgac aagcttgcgc aatttctttg cttctccagt ctactttatt
      121 attaagtttt aaagatagcg agcgctcaga tagccctaaa gccaaggcaa agttgtactg
      181 tgtgccgaac ttctcaacga tccttccgct gagttttgaa taatcaaaaa ccataggaac
      241 ctcctttctt ttttgttcac gttcatgaac tttatgcttt tatgttacac tttgttttga
      301 actttgtcaa tacacaaagt tcattttttt gaattttttt attgaacttt tgttcaagat
      361 gttttataat taacctataa acatcgaaag gaatctactt ttatgcaatg tagttctact
      421 tcaaatagat taaaacaact gatgtcagaa agaaatttaa ggcaggttga tattttagaa
      481 aaatcaaaac cttttcagaa acaattgggg gtaaagatgg gcagaagtac tctttcgcaa
      541 tacgttagtg gcaaatctgt tccagctcaa cgacaactct atcttttatc taaaaccctt
      601 aacgtaagcg aggcatggct gatgggatat gatgtagcca tagagcgcat acctgatgaa
      661 aaacgtggag ctacgacaga aatatctaat caacctgaaa tcgtttctat ctacaaccaa
      721 ctagaacaac ctagacaaga aaaagtcctt gactttgcta aagagcagtt ggaagaacaa
      781 aagcatgaac aaaataacct ttttgaagta acaggtattt cctatgctgc ggctgcaagt
      841 gggctgggta gaggttttga tgttgatgac tacgatacct ataccgtcta tacagatgaa
      901 gaaccaccac gctatgatta tgctattggt gtccgcggtg acagtatgct accaacatac
      961 gaggctggcg atatgctcta tctcgttgat aagggcatgt caaattactc aggtcagctt
     1021 tgtgtaattg catacaacgg tcagacctat tttaaaaagg tttacaccga agctaatggt
     1081 ctacgcttag tctcacttaa taaaaaatat gatgatattt ttattgatta tccaccagca
     1141 gaagatacct acatcaagat ttttgatgtc attggtagct ttgtcccagt agaaatgtaa
     1201 aacaaaaagc cccacactct ccccgaccaa agtttgagtg tgaggtatct cgtacaataa
     1261 agaataggca ttaaatggcc ctctttactg tacccatttt atcaaaaaag aggtacaaaa
     1321 acaatgttta caacaaacaa ggtagcaatt tacgtcagag tttcgactac taaccaagct
     1381 gaggagggct actctattga ggagcaaaaa gacaagcttt ctagctactg caatatcaaa
     1441 gattggagca tttacaacat ttacacagac ggtggctttt cagggtcaaa tactgcgcgc
     1501 cctgccttgg aaaatctcat caaagacgct aaaaagaaga aatttgatac tgtccttgtc
     1561 tacaagctag accgtttgag ccgtagccaa aaggacacgc tctatttaat cgaagaggtt
     1621 tttataaaaa acggtataga atttttgagc ctacaagaaa attttgacac atctactccc
     1681 tttggcaaag ctatgatagg gctacttgca gtattcgctc agttggagcg tgaacaaata
     1741 aaggaacgta tgcaattagg taaactaggt agagccaaat ctggaaaacc aatgatgtgg
     1801 tctaaaccag catatggcta tatatatcac aaagaatctg gagaactcat tgtcaatgaa
     1861 ttagaggcta ttgtggtcag agagatattt aagtcctatc ttgagggaat gtctattacc
     1921 aagctcagag acaaagtaaa tgagaaatac cctaaaactc cagcatggca ctatagaatt
     1981 atcagaggca ttctagccaa tcctgtctac tgtggttaca accaatataa gggacaggtg
     2041 ttccctggta accatgaacc tattatctct gaggaagtct ttaacaagac tcaagaagaa
     2101 ctcaaaataa gacagcagac agcagctgag aaattcaacc ctagaccatt tcaggctaag
     2161 tatatgctct caggtattgc ccaatgtggt tactgccacg ctccgctcac aattattatg
     2221 ggcatgatta ggaaagatgg tacaaggttt ataagatatg aatgcaaaca aagataccca
     2281 agaaaaacaa aaggtgtaac agtctataac aataatgaaa aatgtcactc tggagcttat
     2341 gaaaaaagcg acatcgagga atatgtcctt aaagaaatca gcaagctaca aaatgacaaa
     2401 gactacctag atgagatatt ctcagactct aacactgaaa ctatcgatcg tgaaagttat
     2461 caaaagcaga tagaggagtt atcaaagaaa ctcagcaaac taaatgacct ctatatagat
     2521 gaccgtatca cactagaaga tttgaaaaag aaatcttatg aatttacaag catgaggaca
     2581 ttacttgaga cagagctaga aaacgatcca gcactcaaaa aacaaaaacg aaaagacgac
     2641 atgaagaaga tactcagtgc tgaagatatt ttttcaatgg actacgaggg tcaaaaaatt
     2701 atggttagag gtcttataaa caaagtacaa gtcactgctg atgatgtttt catcaagtgg
     2761 aaaatataaa caattttact atcctgtatt tccagtaaag tgaaggcctg aacaccttga
     2821 tcttttaaga ttgataatct cattttcatt taaaaaacat ctcccatctg ttgataaatt
     2881 ggtaataaaa tagcagcata aatcatcaca ataaccacag caaccactaa aaaaataatc
     2941 ggctggatcc attgtgttgc ccgattaagc tgactaaaaa aggtctccca gctttcttgg
     3001 gaatagatat ctaattcctg accaagcttt gatttgatgt caccatattc aatcattagg
     3061 cttagctcct ttttaaaaaa gggataagct gcaacccttt gatgaaagga ttggccagct
     3121 agtagactct gcttgatatc cttggcaagc tctcgcatga gctgtgactt ttcgtttgac
     3181 atcatctcta aaatggtgat taattctaag ccttgtccga tgaggttgcc ccattctcta
     3241 gcatagtagg ctgtcaaata ttgccgcaat aaggacccaa tgataggata atagctcagc
     3301 tgactaaata gttttagccg actacaggac ttggcatata ggtaaaaaga gccaattagc
     3361 aacagcacaa gcaaacaaaa acctaagaaa taatgaggca aatgaagcaa caagtcagtc
     3421 aaggtatttt gactctctag ctgagggatt aggtaatgac gcaagcctag catgataacc
     3481 actagaaaac ccaaaagtat aatcggataa gtgactgcct cgatggtctt tcgcttgatt
     3541 tggcgaaatt gactcagata gtcctgaatt ttttccaagg ttagcttgat attgccatgc
     3601 ttatctgcca gattaatttg tgtcataaca gcatcagagt aacctaaggc tgctagcatg
     3661 tcagcaaggc cgttgccctt taataggctt gcttccatac ttgtaacata gactggcagt
     3721 agcagctggc tttttctcaa aaaagcaatg acctctgtca aattaaagcc gttagacaat
     3781 aggttataga gcaattggat aagcttttcc tgctgcttac tggataattt tttcaagcct
     3841 tgcctgcctg gtattgagat gtccctccgc aagaagctga tcaatctgct gattccaccg
     3901 gttggcttga tgatgttcaa attccttttg tgcacaatca attaaagcac ctccactaat
     3961 aaatcgctgg taagcaacca ttgctagact attatccaat tctgccctag aaatgcctaa
     4021 ttctagcagt ctagcgtaaa cgcctgaaat actctttgca tggacggttg aaaagaccat
     4081 tgctcctgtt aggctagccc taataaccgc tctagcagtc tgtgtatctc taatttctcc
     4141 gataatcaac acatctggac gatgacgcaa ggaaagctta atcagattat cgtatgtcat
     4201 gccaatgcta tcgttaacct gtaattgcag gagctggtca ttttttattt ccacaggatc
     4261 ctcaatactg atcacctgaa gctccttgca atagtcagag actagctgat acatcagggt
     4321 tgtcttacct gatcccaccg gtccagaaaa gaggtaaagg cctctagctc caatagctga
     4381 tgtgactcgc tctaaaccat caaaccaata cctgagctgg cgttgatgat gatacaagag
     4441 acgaataacc aagctctcct gtccctgata atcacccaca gctgataatc gtagagacac
     4501 cttagtgtca tcaaggtcgt agtcacaagc accgagctga cagcgtcttt tttcgcccac
     4561 attcattcct gcaacgaact taaagtgact aataagatta gccatccgat cactttcaca
     4621 aacatctatt agcctcctat catcacctac cctcatcaaa agctcatagc ctgtccccct
     4681 tggtagtata taaatatcct gagcctgcaa ttcttcagcc tgcctgataa gccgcttggc
     4741 taattcttga atcattctta cctcctcact aagactattc gaaaaataaa aaaaatagcc
     4801 tcaagaaaaa ggccattttt tgataaatgt ttaacatcaa gtaaggaatt cagcacgcta
     4861 caaacagcgc agaatccttt tgcgatgcta tgatgacaag gtcaagcctt aatcacttag
     4921 ctagtccagg ctttatttag agcctggtga ggctgctaag ctgatcaaca gagatgacct
     4981 catctgccat ttcccaaatg cttgggctgt gggttgcgat gataattgtc cgatttttat
     5041 gccgaagtga cagcaaaata gccataattg ccttagaagc ctctggatca atagaagccg
     5101 taggctcatc agctaaaata aagggaggat cttttagcat caccttagct agggcaacac
     5161 gctggtattc accaccagac aattcaaaaa caggcttttc taagctcaga taatccaagc
     5221 caactgccct tagggcttct aattcccttt gccggccttc ctccttgctt attttttgac
     5281 caattagccc tagcttcaaa ttatcagcaa tcgtctgact ctccaacagc ccaaaatgct
     5341 gaaataggta gcccaattcg tgacggaaaa aatcgctgga tctgtatgtt ttcaagtttt
     5401 ttccacgaaa gaaaatctca ccctgataat cctcaagagc tgccagcata ttcatcaagg
     5461 ttgtcttacc actaccgctt gacccaatca gggcataaac ctttccagac tcaaaggtca
     5521 ttgacaaatc agaaaataag acacgatcac caaagcattt actaaccttt tctaatcgaa
     5581 tcatactaag ctcctttcaa aatcagcagc gacatcttat tttctattct catttgccga
     5641 tatagtagca atatggcatt ccctagaaat aggaagaaaa ccagcaggca cataagagga
     5701 ttctgtgtta acagggcact aatcaccaat ccaacaaaga aaacaagcag ctgcgacagc
     5761 aaataacgac gatgcagctc aaaaaatcta agaccagaga cgcgcttaat gaaaatatcc
     5821 cgtctaaatt cttcaaagta gagaaggttc attgtgttaa acatcaacat agaggtcgct
     5881 atccctaata tagctcctgc aatcatcaac caaatctccc tacgaagatt gttcaacaat
     5941 gtctcataaa tgcgatagcc agtttttagc tctcctaccc agttctcaat accgttttgc
     6001 ttgatgagcg tttgagtatc tgccaactga tcgaaaagga aataattttg taaagcaacc
     6061 tcccaaaagg cataggcttg ttcgccagtt gacttaggcg tcaaaacaac aataatggga
     6121 tcccttaaaa actgctgata ggatatcggt gttgtgttat aaagaaagcg ttcctggcct
     6181 gtctttgtat aagaaacagt agcagtcatc ggctgatgac cctcacctga agcaagccca
     6241 gttacagctg attcaaagac cgattggtac tgtgcagcct gtgttttcaa atgctctggt
     6301 aaaagaagga caaattctcc aagggacagc tgattgattt tttcactaat atcaggtgcc
     6361 acctcaactt tttggtgctt cacatattga ggcgttacaa gcagcacatt cccttgtgga
     6421 ctgtaatcat tccaactaga agaggctgtt agcatagaga ggcctgattg caggtcgcgc
     6481 tcgactaggt aatgacgaga caggatcgct ccatgctctg aaacagcctg atccataaca
     6541 tgaaaccaag tcttttgttt ggcaatagct tccttcgtat ttccaatatc taagccatca
     6601 cgtcctatta aaagagtaac cagcctatcc tcttgtagcc aagcagcctg cccctgcttc
     6661 tgctgtcttt cagcctggac ataaagaagg gtccggctag cgccaaagga aacaaccagc
     6721 actgccaaca attgggcaat taaaatcaag ctaatgatac ctctgacagg tatctgacct
     6781 ttaatcacct gcatcaaatg cactctttta atcccaatta caaataaacc agcaaagaaa
     6841 agggcaatag ctatcagcaa aagattatag caaacaagac ctatcccaat caggtaaaga
     6901 acaagcggtg aaaaagacat aagctgactc ataatagccg ccaggctaag gccaagtagt
     6961 aggcctagac agcaatagca cacatcagac ctgattggat aaagaaagat ctgccagcga
     7021 cgttcacctg aaatcaagcg gatacccact gctcgcagcg tgcgaatatg gccaatcaag
     7081 gtcaaagccc caaaggttag acagaatatc acaatcccta aagcctgaga accactgcta
     7141 aaaatcaaaa cgagagtccc taaaaatgaa ggcttcagcg ctgtcatttt ggtcataccg
     7201 agcccagcta atgtgtctct tagtcgctct acagtcaagc cgcctttaag aataaagtaa
     7261 ttattctcca cactaagcct tgatggttcc tcaataacct tttcagctag tccaccaggt
     7321 agctttccct tgccaaataa ggtataggtc acaataggtg taccttctgg ccctggctcc
     7381 tggtgctgca ttgcaattaa gctgtctgtt tcatctgcta gacgggttaa gcctgcttca
     7441 acctgattat agcttgcctt aggcgaagca tctaaaacaa caacagacgg ataataatga
     7501 gaaacaaagg tatctgacca gatcgtaaat acccaaacca aaaagaggct aactagtata
     7561 ttagacaata tgataaacag tctcttcata acccactcct taccttaaaa gggacggagt
     7621 ctctccgccc ctaataaaca cacactgacc tgcctatttc cctgcatcaa aggtcacgtg
     7681 ctctccaaaa ttagtattga taaaagcata ggagtagtaa ccagcaccag accatgcacg
     7741 cctctgatta tcacgtcctg agctctccac aaaggaccgg tgagaagagg tcagaaggtc
     7801 acctattgaa aacgccttca atcataaagg acatggcgat taccacaata ccactcaaat
     7861 cattaactat ttaacaaaaa tata
//
LOCUS       DARYXS010000086         7784 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.087, whole genome shotgun sequence.
ACCESSION   DARYXS010000086 DARYXS010000000
VERSION     DARYXS010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7784
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.087"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            213..3779
                     /gene="rpoB"
                     /locus_tag="TV193_001602"
     CDS             213..3779
                     /gene="rpoB"
                     /locus_tag="TV193_001602"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1513779.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN"
     gene            3870..7505
                     /gene="rpoC"
                     /locus_tag="TV193_001603"
     CDS             3870..7505
                     /gene="rpoC"
                     /locus_tag="TV193_001603"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEL1513780.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQ
                     EYGHGSFIAKMGAEAIQDLLKRVDLVTEIAELKEELKTATGQKRIKAVRRLDVLDAFH
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVIREIVAREFAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKLWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLKPGQNIQEVIDSLPINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGTVIEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKHLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMVRYRNIEPQAINEVEVIEEAEATE
                     EPAIIKE"
     gene            complement(7597..7784)
                     /locus_tag="TV193_001604"
                     /pseudo
     CDS             complement(7597..7784)
                     /locus_tag="TV193_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2114 a         1545 c         1936 g         2189 t
ORIGIN      
        1 taatctagct gaaatattgt ccagctagaa agaacagcag ttaaatcaca ctgataaggt
       61 ccgatttagc tgctcttttt gtgcctattt ttagataaaa atcaattttg taacaaaaat
      121 ttaaagattc taaaaatacc acttaagaca aatattgatg ttgcaattgt ttgcttgata
      181 gcaaagctta aaaagaaaaa ggagctaaaa acttggcagg acatgacgtt caatacggga
      241 aacatcgtac ccgtcgtagt ttttcaagaa tcaaagaggt tcttgattta ccaaatttga
      301 ttgaaattca aactgattca ttccaagatt tcttagattc aggcttgaag gaagtatttg
      361 aagatgtgct tccaatctca aactttacag acacgatgga gcttgagttt gttggttacg
      421 aatttaagga gcctaaatat acccttgaag aggctcgtat ccatgatgca agctattctg
      481 caccaatctt tgtgaccttc cgcctgatta ataaggaaac tggcgaaatc aaaacacaag
      541 aggtcttttt tggtgatttt ccgattatga ctgaaatggg aacctttatc atcaacggtg
      601 gagagcgtat tattgtttct cagctggttc ggtctcctgg tgtttatttc aatgacaagg
      661 ttgataaaaa tggtaaggtt ggttatggct caacagttat ccctaatcgt ggtgcttggc
      721 tagagctaga aactgactca aaggatattg cttatactcg tattgaccgt acgcgtaaaa
      781 tcccatttac aacgctagtg cgtgcacttg gtttttctgg tgatgacgaa attattgata
      841 tttttggtga tagtgagctt gttcgcaata ccattgaaaa ggatattcat aaaaaccaaa
      901 gcgattcacg tacagatgag gctcttaagg aaatttatga acgcttaaga ccaggtgagc
      961 caaagacagc tgatagctca cgcagccttt tgacagctcg tttctttgat gctcgccgtt
     1021 atgacttggc agcagttggc cgttataaga ttaataaaaa gctgaacatc aagacacgtc
     1081 ttttgaatca aattattgct gaaaatctaa tagatagtga gactggagag attctggttg
     1141 aggctggaac agagatgact cgtagtgtga ttgagtcaat cgaagagcag cttgatgggg
     1201 atttgaacaa gtttgtctac acaccaaacg attatgcggt ggtgacagag cctgtgatcc
     1261 tacaaaaatt caaggtggtt tcaccagttg atcctgatcg tgtggtgacg atcgttggta
     1321 atgctaaccc agatgataag gttcgtgccc ttactccggc tgatattttg gctgagatgt
     1381 cttatttcct taaccttgct gaaggtcttg gaaaggtcga tgacattgac cacttaggta
     1441 atcgtcgtat ccgtgcagtt ggtgaattgc ttgctaacca attccgtatt ggtcttgctc
     1501 gtatggagcg caatgtccgc gagcgtatgt ctgtacagga taacgatgtg ttgactccac
     1561 aacagattat taacattcgt cctgtaacgg cggctgtcaa agaattcttt ggttcttcac
     1621 agctatcaca gttcatggat cagcacaacc cattgtctga gttgtcgcac aaacgtcgtt
     1681 tgtctgcctt aggacctggt ggtttgacac gtgatcgtgc tggctatgag gtgcgtgacg
     1741 tgcactacac tcactatggt cgtatgtgtc cgattgaaac acctgaaggg ccaaatatcg
     1801 gtttgattaa taacctgtct tcatttggac atctgaacaa atacggcttt attcaaaccc
     1861 cttaccgtaa ggttgatcgt gtgattggcc gagtgactaa tgagattgtt tggctaactg
     1921 ctgatgaaga ggatgagttt acagtggctc aggctaattc taagctcaat ccagacggta
     1981 cctttgctga agagattgtc atgggacgtc accaaggtaa taaccaagag tttcctgcta
     2041 gtcaggttga ctttgttgac gtgtctccta agcaggtagt cgctgttgcg acagcatgta
     2101 ttcctttcct tgaaaacgat gactccaacc gcgccctaat gggagctaac atgcagcgtc
     2161 aggctgtgcc attgattgat ccaaaggctc cttatgttgg tacgggtatg gaatatcaag
     2221 cagctcatga ttcaggtgct gcggtaattg cccagcataa tggtaaggtt gtcttttcag
     2281 atgctgaaag agtagaggtg cgtcgtgagg acggttcact tgatgtttac cacatcacaa
     2341 aattccgccg ttcaaactct ggtactgcct acaaccaacg aacccttgtt aaaataggtg
     2401 atattgttga aaagggtgac tttatcgctg atggcccttc tatggaaaaa ggtgagatgg
     2461 ctcttggtca aaatccaatc gttgcttaca tgacctggga agggtacaac tttgaggacg
     2521 cggttatcat gagtgagcgt cttgtgaagg aggacgttta tacctctgtt cacttggagg
     2581 agtttgaatc agaaacacgc gacacaaagc ttggacctga ggaaatcaca cgtgaagtgc
     2641 caaacgttgg tgaagaagcc ctcaaggacc ttgatgaaat gggtattatc cgtatcggtg
     2701 cagaggtcaa ggaaggcgat attcttgttg gtaaggtaac tcctaagggt gaaaaagacc
     2761 tttctgctga agaacgtctc ctgcatgcta tctttggtga taaatcacgt gaggttcgtg
     2821 atacctcgtt acgtgttcct catggtggtg acgggattgt acgtgatgtg aagatcttta
     2881 cacgcgcaaa tggtgatgag cttcaatcag gtgttaatat gctggtgcgt gtttacattg
     2941 ctcaaaagcg taaaatcaag gtcggagata aaatggccgg gcgtcatggt aacaagggtg
     3001 tcgtctcacg tattgtaccg gttgaggata tgccatatct gccagacgga acccctgttg
     3061 acatcatgct gaaccctctt ggggtgccgt ctcgtatgaa cattggacag gttatggagc
     3121 ttcacctagg tatggctgct cgtaatttgg gtatccatat cgcaacaccg gtctttgacg
     3181 gagctacgtc tgaggacctt tgggaaactg ttcgtgaagc aggtatggat agcgatgcta
     3241 agactgttct ttatgatggc cgtactggtg agccgtttga taatcgtgtg tcagttggtg
     3301 tcatgtatat gattaagctt caccacatgg ttgatgataa gcttcacgcg cgttctgtag
     3361 gaccatactc actggttacc caacagccgc ttggaggtaa agctcagttt ggtggccaac
     3421 gttttggtga gatggaggta tgggctcttg aggcttatgg tgcttcaaac gttcttcagg
     3481 aaatcttgac ctataagtca gacgatgtga atggtcgctt gaaagcttat gaggcgatta
     3541 ccaaaggtaa gccaattcca aagcctggtg taccagaatc tttccgcgtt cttgtgaaag
     3601 aattgcaatc acttggtctt gatatgcgtg tccttgatga agacgataat gaagttgagc
     3661 ttcgtgatct tgatgaaggc gaagacgatg acgtgatgca cgttgacgat cttgaaaaag
     3721 cgcgtgaaaa gcaggctcag gaaactcaag atattgctga atcaactgaa gacaactaaa
     3781 tcataaacat ttgtaacaga aataatgact agactagggc tatttgccct agctgctagt
     3841 aagtcatcaa aggcagaaag gtaaaactag tggttgacgt aaatcgtttt aaaagtatgc
     3901 aaatcacatt agcttcacca agtaaggtcc gttcatggtc ctatggtgaa gttaaaaaac
     3961 ctgaaacaat caactaccgt acattaaaac cagaacgtga gggtcttttt gacgaagtca
     4021 tttttggacc aaccaaggat tgggagtgtg cgtgtggcaa atataaacgt attcgctata
     4081 agggcattgt ctgtgaccgt tgtggggtcg aggtaacgcg tgcaaaggtt cgtcgtgaac
     4141 gcatgggaca cattgagctg aaggcacctg tctcacatat ctggtatttt aagggaatcc
     4201 catctcgtat gggcttgact cttgatatga gtcctcgtgc tcttgaggag gtaatctatt
     4261 ttgcggctta tgtggttatt gatccaaagg acacaccgct tgagccaaaa tcactattga
     4321 cagagcgtga atatcgtgaa aaaatccaag aatatggaca tggctcattc attgctaaaa
     4381 tgggggcaga ggctattcaa gacctcctaa agcgtgttga tttggtcaca gaaattgctg
     4441 agctaaagga agaattaaaa acagcaacag gccaaaagcg tatcaaggct gttcgtcggt
     4501 tagatgtgct tgatgccttt cataaatcag gcaataagcc agaatggatg atcctgaaca
     4561 tcttgccggt cattccacca gatcttcgtc ctatggtgca attggacggt ggccgctttg
     4621 cagcctcaga cttgaatgac ctttaccgtc gtgtcattaa ccgtaataat cgtttagcac
     4681 gtttgttgga gcttaatgcg cctggtatca ttgtgcaaaa tgaaaagcgt atgctgcaag
     4741 aggcggttga tgctttgatt gataatggtc gtcgtggtcg tcctattaca ggacctggta
     4801 gtcgtccgct taaatccttg agccacatgc ttaaaggaaa acaagggcgt tttcgtcaaa
     4861 acctgcttgg gaagcgtgtt gacttctcag gtcgttcagt tattgctgtg ggtccaacgc
     4921 taaaaatgta ccaatgtggt gtaccacgtg agatggctat tgagcttttc aagccatttg
     4981 tgatacgtga gattgttgcc cgcgaatttg ccggcaacgt caaagcagct aagcgtatgg
     5041 ttgagcgtgg cgatgagcgt atctgggata ttctagaaga ggttatcaag gagcatccag
     5101 tcctgcttaa ccgcgcacct acccttcaca gattagggat tcaggccttt gagccggtgc
     5161 ttattgatgg taaggctctt cgtcttcacc cgcttgtgtg tgaggcctac aatgccgact
     5221 ttgacggaga ccaaatggct attcacgtgc cgctttcaga ggaagcacag gcagaggctc
     5281 gtttgttgat gcttgctgct gagcatattc ttaaccctaa ggacggtaag ccagttgtaa
     5341 caccttctca ggatatggtg ctaggaaact actacctaac aatggaagat gctggtcgtg
     5401 aaggcgaagg tatggtcttt aaggacaagg acgaagcggt aatggcttac cgtaatggct
     5461 atgttcacct tcatagtcgt gttggtattg ctgttgacag tatgccaagc aagctttgga
     5521 aggatagtca aagacacaaa atcatggtga caacggtcgg taagatcttg tttaatgaca
     5581 tcatgccaga ggaccttcct tacctccaag agccaaataa tgctaacttg acagagggca
     5641 ctccagataa atatttcttg aagccaggtc agaatattca ggaggttatt gatagcttac
     5701 cgatcaatgt gcccttcaag aagaaaaatc ttggtaacat cattgcggaa accttcaagc
     5761 gtttccgtac aacagaaaca tcggcctttc ttgaccgctt gaaggacctt ggctactatc
     5821 attcaaccct tgcgggcttg acggttggga tcgctgatat tccggttatt gacaacaagg
     5881 ctgagatcat cgaggctgct caccatcgtg ttgaggaaat taataaggcc ttccgtcgag
     5941 gcttgatgac tgatgatgat cgctatgttg cagtcacaac aacatggcgc gaggcaaaag
     6001 aagcccttga gaagcgtctg attgaaacac aggatcctaa gaacccaatc gttatgatga
     6061 tggactcagg agcgcgtggt aacatctcta acttctcgca gcttgccggt atgcgtggct
     6121 tgatggctgc tcctaatggc cgtattatgg agcttcctat cctgtctaac ttccgcgaag
     6181 gcttgtctgt tttggaaatg ttcttctcaa ctcatggtgc tcgtaagggt atgactgata
     6241 cggctcttaa gacagctgac tcaggctatc tgacacgtcg tttagttgat gttgcgcaag
     6301 atgtcatcat tcgtgaggac gattgtggta cagaccgagg ccttcttatt cgagctatca
     6361 cagatggcaa ggaagtcact gaaacacttg aggagcgctt gcagggtcga tacactcgta
     6421 aatcagtcaa gcaccctgaa actggtgagg tattgattgg tgctgaccaa ttaatcactg
     6481 aggacatggc tcgcaagatt gttgatgctg gtgttgaaga ggttaccatt cgctcagtat
     6541 ttacctgtgc tactcgtcat ggagtgtgtc gtcactgtta cggtatcaac ctagcgacag
     6601 gtgatgcggt tgaggttggt gaggctgttg gtactatcgc tgcccaatct attggtgagc
     6661 ctggtactca gctgaccatg cgtaccttcc acacaggagg ggttgcctct aataccgata
     6721 tcacacaggg tcttcctcgt atccaagaaa tctttgaagc gcgcaaccct aaaggggaag
     6781 cagttatcac agaggttaag gggactgtta ttgagattga agaggacgca tcaactcgta
     6841 ctaagaaggt ctacgttcaa ggtaaaacag gcatgggtga atatgttgtg ccatttacag
     6901 cgcgtatgaa ggttgaggtt ggtgatgagg tcaatcgtgg agctgccctt acagaagggt
     6961 caatccagcc taagcacctc cttgaggttc gtgatacctt gtcagttgag acctacttgc
     7021 ttgctgaggt tcaaaaggtt taccgcagcc aaggggtaga aatcggagac aagcacgttg
     7081 aggttatggt tcgtcaaatg cttcgcaagg tacgtgtcat ggatccaggt gatacagatc
     7141 ttctgccagg aaccttaatg gatattgcag actttacaga tgccaataag gagattgtta
     7201 tctctggagg tattcctgcg acctctcgtc cagtgcttat gggaatcaca aaagcctcac
     7261 ttgagactaa ctcattccta tcagcagctt ccttccagga aaccactcgc gtgctgacag
     7321 acgctgctat ccgaggcaaa aaagaccatc tattggggct taaggaaaat gttatcattg
     7381 gtaagatcat tccagcaggt actggtatgg ttcgttaccg taacattgaa ccgcaagcta
     7441 tcaatgaggt tgaggttatc gaagaagctg aagctacaga agagccagca attattaagg
     7501 aataagaaat aaaaggagct agccttagct ccttttatca tgctaaaatc attagattaa
     7561 ttgggctcca tgtcaactat agtaggtgac tgataactaa gcacgagagg agacgaaggt
     7621 cgtcttctct tttgtcatgt tcaaagcaag catagataag tttcttgaaa ttgtcaacgt
     7681 ttctgaatcc aaatgcattg cgcttgatgt ctttgatcag tttgctagtc gcttcaaact
     7741 tggcgttaga ataaggtagt tcaatggcat tagtgatata gtct
//
LOCUS       DARYXS010000087         7496 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.088, whole genome shotgun sequence.
ACCESSION   DARYXS010000087 DARYXS010000000
VERSION     DARYXS010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7496
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.088"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(25..834)
                     /locus_tag="TV193_001605"
     CDS             complement(25..834)
                     /locus_tag="TV193_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1513781.1"
                     /translation="MSEVGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRRPEDLDAILITHEHSDHIKGVGIMARKYNLDVYANEKTWQMIDERHMIGNLDV
                     AQKHVFERGKTMTFGDIDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRLAG
                     IIENADGYLIESNHDVEILRAGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGNKTKK
                     IYLGHLSQENNIKELAHMTMVNQLAMADLGVGTDFTVHDTSPDTACPLTDI"
     gene            complement(838..2190)
                     /gene="vicK"
                     /locus_tag="TV193_001606"
     CDS             complement(838..2190)
                     /gene="vicK"
                     /locus_tag="TV193_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEL1513782.1"
                     /translation="MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLM
                     SHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
                     VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVT
                     QLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKAR
                     SRAQGGAGLGLAIAKEIIKQRRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
                     "
     gene            complement(2183..2893)
                     /locus_tag="TV193_001607"
     CDS             complement(2183..2893)
                     /locus_tag="TV193_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1513783.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
                     LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSR
                     PEYILTRRGVGYYMKAYD"
     gene            complement(3092..4111)
                     /locus_tag="TV193_001608"
     CDS             complement(3092..4111)
                     /locus_tag="TV193_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1513784.1"
                     /translation="MVKKGGQLMKQDMLARYQALKPYVRAGLSSTSQQLLAAASAIDA
                     RLGSPTFLAIWQCEKQCRSPKELLGLVLDLVGMPIELSGRLEDTQALLSRFYPDLPPD
                     HCFWVELAQMVSLAFPDKELAQQSALAKGLHQLRYLISSQQAQYIRSHFRSEDMTDAQ
                     ALAIFLKDKKGPAFWRSQPDYTLMESARLHNKLKLVNGLASFPDHEISHNIKILLHFH
                     TEFILDSQGCFLNEIDGEVVTNKGIINGASFNYGTAGKRHWELDVAPISRHDPTFRKK
                     CLVGHQAPKWLKRSWLQLSPLDFDYSYFNAKGFFSLNSKSCFALVKRQARAFRWQIWR
                     SRFFK"
     gene            complement(4157..5419)
                     /locus_tag="TV193_001609"
     CDS             complement(4157..5419)
                     /locus_tag="TV193_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1513785.1"
                     /translation="MLSRLLAWASQAPQRPAILTDQKTLTYQDLVEQILAYQPQESIS
                     YPTLIVKRDCFQQLIAFCYHLQHGNYPLICHPNLPEQEQRRLSSCDPPSDKAAFAVLS
                     SGSTGRPKVFWRSWASWSNFFEQQNQLFYFSEQTRLFSHGSLSFTGNLNLALAQLWAG
                     GCLVFSDQRSFKGWSSVWRRQKVTHLYLLPSLLQRLLPYFSADSYFAPYLLTSSQHLS
                     PELIRSYYQRFPRLELLMFYGASELSFISWCQGFEAMAIAGFVGRPFPQVKLELREGH
                     IFVQTPYAIEGIEQPYSVDDVGEMTAAGLILKGRTKDWVNQQGVKCHLPSLVQLVHQS
                     GVVQEAAAIKGGSSAADEHVILCLVLKKQGSLTAVKAYLEAHLSPAQRPKRYILLKEL
                     PLNDSGKLDSRRLSQLAHKSTKAAHNTK"
     gene            complement(5409..6524)
                     /locus_tag="TV193_001610"
     CDS             complement(5409..6524)
                     /locus_tag="TV193_001610"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEL1513786.1"
                     /translation="MIDVYIQRGLRTPIGLAGKQFARVRPELLGAQLINALVKADKLA
                     IDEVICGNAVGTGGNIGRLMTLYSDLGETVPAITVDMQCASAGAALTMGYAKIKAGLA
                     TSLLAGGIESSSLQPQRIYAAADSRSGAYQVAQFSPDTSSQLAMIAGAERVAQAYQMT
                     PSQLNQWTLTSHQRAHIARQKHWLADIILAMPGMSDQGIRPRLSEKVLSKVPPILDKA
                     GLISAANTCLTHDAAAFLVLSNQRSAYQILDLVEVAGNPKTSPQMVVEASQVLLARNG
                     LAMTDMDAIEWNEAFAVIDLLFEHYFVEALDRYNIFGGALAYGHPFGASAAIIILHLM
                     QALALKQGRYGLAAIPAAGGQAFALLLEYHKDYSHAI"
     gene            complement(6521..7060)
                     /locus_tag="TV193_001611"
     CDS             complement(6521..7060)
                     /locus_tag="TV193_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513787.1"
                     /translation="MRQLIAAMVEKNQDLPRNILVAEMSLEKAVQPDDYRVKDYRNLR
                     QIRLTTSGLVLEVRLLKGLPARWLKKDTSAKPSKAVNSRALAEHSHVLSVNQAALQQF
                     LAETGDQNPLHQTAPYILPGALLMEEVSSWLTLDYRRLSLRFYAPAVVNAPIHLVMRE
                     KAISLYQAGELVAKGELHV"
BASE COUNT         2080 a         1799 c         1599 g         2018 t
ORIGIN      
        1 acaagcaggg gtgaagtcat aaggctagat gtctgtcaag ggacaggcgg tatctggtga
       61 ggtgtcatga acagtaaaat ctgttccaac acctaaatct gccattgcta gctgattgac
      121 cattgtcatg tgtgctaatt ctttgatatt gttctcctgg cttaggtgac cgaggtagat
      181 tttctttgtt ttattgccca agcttcgaat catagcgcca gcaccatctt cattggataa
      241 atgccctagg tcagataaga ttcgctgctt gaggctccaa ggataagagc cggctcgcaa
      301 tatctccaca tcgtgatttg actcaatcaa gtagccgtca gcattttcaa tgatcccagc
      361 caagcggtcg ctcacatatc ctgtatccgt cagcatgaca aaggacttgt tatccttcat
      421 aatgcggtaa aactgtgggt ctacagcgtc atgactaaca ccaaagctct caatgtcaat
      481 gtctccaaag gtcatggtct tacctctttc aaagacatgc ttttgtgcga cgtctaggtt
      541 gccaatcata tgacgctcat caatcatctg ccaagtcttt tcattggcat agacatctag
      601 gttatatttt cgagccatga ttccaacacc cttgatatgg tcggaatgct cgtgggtaat
      661 caagatagca tccaaatcct caggccttct gtcaatctca gcaagaagac tggtgatttt
      721 ctttccagtc agtcctgcat caatcaacag tcgcttcttg ggcgtttcca agtaaaagca
      781 gttacctgtc gatcctgatg ctaaaatact atatttaaag ccaacctcac tcatcaatta
      841 atcaatatca tcctcccatt catcatagat agcagcatcc ttttcgtaag gtaacacaat
      901 ggtaaaggtt gaccccttgc catagtcact cttagcccag ataaagccgc ggcgctgctt
      961 aataatttct ttagcaatag ccagccctaa gccggccccc ccctgcgccc gacttctagc
     1021 cttatccact cggtaaaaac ggtcaaaaat caaaggcagg tccttctttg gtatgcccaa
     1081 tccctcatca gaaatcgaaa tgattagctg ggtatctgtt gttttcatgt ttacgataat
     1141 tttcccacca tcaggtgaat atttgatggc attgtttaaa atattttcaa tgacctgcgt
     1201 cattttatcg ttatcaattt ctagccaaat agaggtgata gggtaatctc tgacaatttc
     1261 ataggatttt ccagtactgg tgtgctgatt tttcaccaaa tcaaagcggt ttaagataga
     1321 ggtcataaag gctgtaaagt tggtcatttc aacagacagc tgtgtcacat gattatcaat
     1381 tcttgataga ttgagcaaat ctgaaatcat gcgcatcatg cgattggttt cgtctagtga
     1441 gacctttata aagcttgggg ctatgtcctc ctttagcgcg ccctcatcta gagcctctag
     1501 gtatgacttg acagaggtca aaggtgtgcg aagctcatgg ctaacatttg agacaaagag
     1561 tctgcgctca cgctcctcct tttcctgctc agtcgtgtca tgaagcacaa caactagacc
     1621 tgaaataaag ccgctctctc gcctattaag cgcaaaacgc agccgcagcg aaacaaactc
     1681 tcctgtgtca ttacgacgat ttaaggtcac aatcggtgtt tttgagacca gctctcggta
     1741 ggtgtaaggt gagtcactgt ctaataaatc tgtaatgttt ttttccagcg cctgctcacg
     1801 atttaaattg agctgctttt gagcagtctc attaatcatg ataatcttgc cggaacgatt
     1861 ggtcgcaagg accccatctg tcatataagc caaaatacta gcaagacgat ttttctcttg
     1921 ggcaaggttt tcatgggtca gacgaaaaac atctgatagg tcgttgagct gctcagacag
     1981 ctccatcaat tcaatatcag ccttttcatt gatcgtatca gtatagcgac cattgatcaa
     2041 atctcttatc ttatggctca tcagacgaat gatccgagca ttgcgataat cacgaatggc
     2101 taaatgaatg aaataaaaag caacaaaaac aagcaataag agtatggcta gctcaaatgc
     2161 agaaaggttt ccaatgatgt ccttagtcat aagccttcat gtagtaccca acaccacgtc
     2221 ttgtcaaaat atactctgga cgactcggtg tatcctctat tttttcgcgc aggcgacgga
     2281 tagtaacgtc aacggttcga acatcgccaa aataatcgta gccccatacg gtctcaagca
     2341 aatgctcacg tgtcatgacc tgtccgatat ggtttgccag atgatgcagc aattcaaact
     2401 cacgatgggt cagctcaacc tcttgaccat gctttttagc gataaaggca tctggtaaaa
     2461 tctgtagatt gccgatggtt agctcctgag agcctgagga ggcattttct tcggctactg
     2521 ctgtctcaat agtctctgtc cgacgcaaat gtgccttgac acgcgccagc agctcacgat
     2581 ttgaaaaggg cttagtcaca taatcatcgg cccctatttc aagtccaatc accttatcaa
     2641 attcgctatc cttagcagat agcatgatga taggaatatg gctggtcttg cggatttcct
     2701 tggctacctc aaggccatct aattcaggaa gcatcaaatc caaaataatc aaatctggct
     2761 tttcctcttc aaagactgca acggcctctt tgccatcaaa tgctgtgacc gtatcatagc
     2821 cttcctttgt cagattaaat ttaatgatat cagaaatcgg cttttcatca tcaacaatca
     2881 gtattttctt catgcttata cctcagaaca tttctcttca ttaattgcta cgctgcctaa
     2941 tccctattcc ataaggattt agagacgaga ccgatcattt tattatgtcc ttttgattat
     3001 atcaaaattt aggagaaatt gacaatgacc actatactag ccacaaaaac gctctctaaa
     3061 tacctcatca agcaagccag ctactgatcc attacttaaa aaatctgcta cgccagatct
     3121 gccatctaaa ggcacgtgcc tgtcgcttaa ccaaggcaaa gcagcttttg ctattgaggc
     3181 taaaaaagcc cttagcatta aaataagaat agtcaaaatc tagtggcgat aactgaagcc
     3241 aagagcgctt cagccactta ggagcttggt ggcctactaa gcattttttc ctaaaggtcg
     3301 ggtcatgtcg gctgatagga gcaacatcta gctcccaatg cctcttgcct gctgtgccat
     3361 aattgaagga ggctccgtta atgattccct tgttggtcac cacttcacca tctatttcat
     3421 taagaaaaca cccctgacta tcgaggataa attcggtatg gaaatgcaac agaattttaa
     3481 tattatggga aatctcatga tcaggaaagc ttgctaatcc attgacaagc tttagcttgt
     3541 tatgcagacg agccgattcc ataagcgtgt agtcaggctg gctgcgccaa aaagctgggc
     3601 cttttttatc cttgagaaag atagccagtg cctgagcgtc agtcatgtcc tctgatctaa
     3661 aatggctgcg aatatattgt gcctgctggc tcgaaatgag atagcgaagc tgatgaagac
     3721 ccttagctaa cgcgctctgc tgcgctagct ccttatccgg aaaagcaaga ctaaccatct
     3781 gggctagctc cacccaaaag caatgatccg gtggcaagtc aggataaaag cgactcagca
     3841 gagcctgcgt atcctctagc cttccggata actctattgg catgccgaca agatctagaa
     3901 caagccctag taattccttg ggagatcgac actgtttttc acactgccaa atggctaaaa
     3961 aggtcggtga gcctaagcga gcatcaatag ctgaggcagc tgccaatagc tgctgagagg
     4021 tcgaggaaag acctgctctt acgtaaggct tgagtgcctg ataacgtgct aacatatcct
     4081 gcttcatcaa ctgacctcct tttttgacca tattatacca tattgagctg atgctttggg
     4141 ctcaggtgac ttttccttat ttggtgttat gagcagcttt agttgatttg tgggcgagct
     4201 ggctaagcct tctgctatca agctttccac tgtcattaag tggtagctcc tttaagagta
     4261 tataccgttt aggcctctga gctgggctta ggtgcgcctc aagataggcc ttaacagcgg
     4321 taaggcttcc ctgctttttc aacaccaagc acaggatcac atgctcatca gctgcactgc
     4381 tgccaccctt tatcgctgct gcttcttgaa caactcctga ctggtggact agctgaacaa
     4441 ggctaggaag atggcatttg acaccttgct gattcaccca gtccttggtt cgccccttta
     4501 gaatcaagcc tgctgctgtc atttccccca catcatcgac actatagggc tgctcaatgc
     4561 cctcaatggc atagggagtc tgaacaaaaa tgtgcccctc tcggagctcc agctttacct
     4621 gaggaaaggg acgccctaca aagccagcta ttgccatagc ctcaaagccc tgacaccagc
     4681 tgataaagga aagctcactg gcaccgtaaa acatcaacaa ctcaagccgc ggaaagcgtt
     4741 ggtaatagct gcgaatcagc tctggtgaca agtgctgaga tgaggttaat aaatacgggg
     4801 caaaatagct atcagcagaa aagtaaggca gtagccgctg tagcagactc ggtaagagat
     4861 ataaatgagt aaccttttgc ctgcgccaaa cagaggacca gcccttaaag gaccgctgat
     4921 cactaaagac cagacagcct ccggcccaga gctgcgccag agctaagttc aaattgcctg
     4981 taaagctcaa gcttccatgg ctaaatagcc ttgtttgctc cgagaaataa aacagctggt
     5041 tttgctgctc aaaaaaatta gaccaagaag cccaggagcg ccaaaaaacc ttgggacggc
     5101 cagtagagcc agagctaagc accgcaaaag ccgccttgtc tgatggagga tcgcagctag
     5161 acagacgcct ttgctcttgt tctggtagat ttgggtgaca gataagtggg tagtttccat
     5221 gttgcaaatg atagcaaaaa gcaatcagct gctggaagca atcccttttg acaatcaggg
     5281 tcggatagga gatagactcc tgaggctgat aagccaagat ctgctctaca agatcctgat
     5341 aggttagggt tttttggtct gttaggatag caggtctttg tggtgcttgg cttgcccaag
     5401 ctagcagtct agatagcatg tgagtagtcc ttatgatatt ccaataacag ggcaaaggct
     5461 tgaccaccag ctgctggaat ggctgctaaa ccataccttc cttgctttaa ggccaaagcc
     5521 tgcattagat gcaaaatgat aatggctgct gacgcgccaa agggatgacc gtaggcaaga
     5581 gcgcctccaa aaatattgta gcgatcaagg gcctccacaa aataatgctc aaaaagcaga
     5641 tcaatcactg caaaagcttc attccactcg atcgcatcca tatccgtcat ggctaggccg
     5701 tttctagcta ataagacctg actggcctca accaccattt gaggactggt tttaggattg
     5761 ccagcaacct caacaagatc aaggatttga taggctgatc tttgattgct tagcactaaa
     5821 aatgctgctg cgtcatgggt caagcaggta ttagcagcac tgatgaggcc agccttatca
     5881 agtatcggcg gcaccttgct caagaccttt tctgacaggc gagggcgaat gccttgatca
     5941 gacattcctg gcattgctaa tataatatca gctaaccaat gcttctgcct agctatgtgt
     6001 gctcgctggt ggctagtaag ggtccactgg ttgagctgtg agggggtcat ttggtaggcc
     6061 tgagccaccc gctctgctcc tgctatcata gccagctggc tactggtatc tggtgaaaac
     6121 tgagctacct gataagcacc tgatcggcta tcagcagcag catagatacg ctgaggctgc
     6181 aaagagctgc tttcgatccc tcctgctaac aagctagtgg caagacctgc cttgatttta
     6241 gcatagccca tagtaagagc tgcaccagcc gaggcacatt gcatgtcaac ggttatggca
     6301 ggtacggtct ctcccaagtc agaatacaga gtcatcagcc ggccaatatt accgcctgtc
     6361 ccaacagcat taccgcagat cacctcatca atagccagct tatctgcttt gactaaggca
     6421 ttaatcagct gagcaccaag cagttctgga cgcaccctag caaattgctt gccagctaga
     6481 ccaataggcg ttctaagccc tctttgaatg tagacatcaa tcatacgtga agctctcctt
     6541 ttgcgactaa ttctcctgcc tgatagaggc tgatagcttt ttctctcatc actaggtgaa
     6601 taggagcatt cacaaccgct ggggcataaa aacgcaggct tagcctacgg taatctaaag
     6661 taagccagct gctaacctct tccatcaaga gggctcccgg taagatatag ggagctgttt
     6721 gatgaagagg attttgatct cctgtttctg ctagaaattg ctgtaaggcc gcctgattaa
     6781 cgctcagtac atggctatgc tcagctaatg ctcggctatt aactgcttta gaaggcttag
     6841 cacttgtgtc ctttttcagc cacctggctg gtagcccttt tagtaatcga acctctagca
     6901 caagccctga tgtagtcaat ctgatctgcc gcagatttcg ataatccttt acgcgataat
     6961 catctggctg cacagctttt tccaagctca tctcagccac aaggatgttt cttggtaaat
     7021 cctgattttt ctcaaccata gctgcgatta gctgtctcat tgtaaccatc cttttgcgaa
     7081 caagttaact ttattatact gaatacctga acacaagaaa agaaaaaaca gcaaaaacaa
     7141 ggcttagtta gcaaaaaaaa ggcgagcctt tagcctaacc ttttttgtct gatcacatca
     7201 tgttcaatat catttaataa atcaaggctg ctacagcctc tgcctacagg taactgatag
     7261 tcattcagct ctacttgaaa tagacagaag aaagcacaca aggcaagctt caaggtcatt
     7321 cacgcgctag ataagtcgca tgacctatta tcattctaag acattagctg ataaaggctg
     7381 ctgcgaatgt tacggtactc caactaaggc ctagacttgg caaggccatc ctaaaagcga
     7441 tcttaggaca gtgaagaagt aggctgaaac aagggttcag gactatcgtg ccgagg
//
LOCUS       DARYXS010000088         7384 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.089, whole genome shotgun sequence.
ACCESSION   DARYXS010000088 DARYXS010000000
VERSION     DARYXS010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7384
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.089"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(100..594)
                     /locus_tag="TV193_001612"
     CDS             complement(100..594)
                     /locus_tag="TV193_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1513788.1"
                     /translation="MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFS
                     YRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSKANRELIRKNHKNNILLTASFE
                     ALYDRLKKDRLCQRPLFLNHSEAELYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
                     ANMS"
     gene            complement(587..1870)
                     /gene="aroA"
                     /locus_tag="TV193_001613"
     CDS             complement(587..1870)
                     /gene="aroA"
                     /locus_tag="TV193_001613"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEL1513789.1"
                     /translation="MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLR
                     GQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLL
                     AAQDFSVQLLGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQELRPIHY
                     QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKG
                     PQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGRI
                     SYQAVDKDRQAATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQ
                     ELRVKETDRIQAVTDVLGQMGADIQATEDGMVTRGKTPLHGAAVSTCGDHRIGMMTAI
                     AALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD"
     gene            complement(2003..2941)
                     /locus_tag="TV193_001614"
     CDS             complement(2003..2941)
                     /locus_tag="TV193_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEL1513790.1"
                     /translation="MSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTF
                     SKAAIQVLDRHYHLNDNITTLFLFLIQPITILIIFVGLMLLYFLLPNIKIKKIRYILP
                     GTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMIFIIMLWFIFLARILIMGAVF
                     NATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK"
     gene            complement(2943..3803)
                     /locus_tag="TV193_001615"
     CDS             complement(2943..3803)
                     /locus_tag="TV193_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEL1513791.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYV
                     RRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVAHAFPRHYILQEGDLLKVDMVLS
                     EPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
                     MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEINTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            complement(3820..5103)
                     /locus_tag="TV193_001616"
     CDS             complement(3820..5103)
                     /locus_tag="TV193_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1513792.1"
                     /translation="MSKHQDILDYLERLAIGKRVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYAEIARISDSEVLAGHAGLGHEFSKFSIGA
                     MTQQNIHRYLIKGGLLIVGDRENIQLLALKNHNAILVTGGFPVSKQVIETADSQGIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVAQVLIPVEEYGCLYETDTVEEFNALIKK
                     TGQVRFPIVDALDQVVGVVSMRDVVDQPAETRLEQVMSPNPITAKPNASLANISQKMI
                     FEDLNMLPVVDDHHFLLGIITRRQAMENLPNHQPGNLYTYSQQMLSSLEETLDYYQVM
                     IEPTMIDSAGNLSNGVVAEFLKEISVRVLTKKHQKNIIIEQMMIYFLHAVQIDDQLRI
                     YPKIITENRRSSTLDMEVMVDDQVIAKAIITTKLN"
     gene            complement(5096..5650)
                     /locus_tag="TV193_001617"
     CDS             complement(5096..5650)
                     /locus_tag="TV193_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1513793.1"
                     /translation="MDIWTQLARFAFVETQRLLLRPFQYADHQPFYDMISHNSHYQFV
                     FPESMTKAESDFLMVNAFMKEPLGVWLIEDKTSHSMLGSIRLEKYDKQQASAEIGYFL
                     AQPFWGQGLMTEVLKTLTFLAFQEFGLRQLIIVTHLENKASQRVAEKAGFRLTKQFKG
                     SDRHSHHIRDYLEYQLTIGEYHYE"
     gene            complement(5944..7233)
                     /locus_tag="TV193_001618"
     CDS             complement(5944..7233)
                     /locus_tag="TV193_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622582.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1513794.1"
                     /translation="MEKNKKVSYFLRQSAVGLASVSAAFLVGTTSVGALDAATVLEPT
                     TAFIREAVREINQLSDDYADNQELQAVLANAGVEALAADTVDQAKAALDKAKAAVAGV
                     QLDEARREAYRTINALSDQHKSDQKVQLALVAAAAKVADAASVDQVNAAINDAHTAIA
                     DITGAALLEAKEAAINELKQYGISDYYVTLINKAKTVEGVNALKAEILSALPSSEVID
                     AAELTPALTSYKLVIKGATFSGETATKAVDAAVAEQTFRDYANKNGVDGVWAYDAATK
                     TFTVTEQPVAETIEAAELTPALTTYRLVIKGVTFSGETATKAVDAATAEQTFRQYAND
                     NGVTGEWAYDAATKTFTVTEALEESPADPEKPSASLPLTPLTPATKTAPAKQKDKQKA
                     KTLPTTGEKANPFFTAAALAIMASAGALAVTSKRQQD"
BASE COUNT         2086 a         1810 c         1354 g         2134 t
ORIGIN      
        1 gaattcaact ttatttcaac ctatatatta gcttttcata cctaatcatt aagaaaagct
       61 gggctgcgaa taggaggcca aaagtctaat cctcagcagt tacgacatat tggcaatgat
      121 tgctgcaacc tcctttggtg ttctatgctc aacattaatc actttgtctg ccaatccctc
      181 atacaaggcc atgcgctgct gaaaaatagc atagagttct gcttcagaat gatttaaaaa
      241 cagtggtctt tggcatagcc tatctttttt aagccgatca tacaaagcct caaaggaggc
      301 tgttaagagg atattatttt tgtgattttt tctgattaat tctcggtttg ccttactaag
      361 gacaacacct ccaccagttg atacgatagt ctcattatca agtgccagca cttcctgtaa
      421 ggtatctgac tcaagctttc taaaggctgc ttcaccacga taggaaaaaa atgctgatat
      481 gctcatgcct attttagcct caataagcct atccatatcc aaaaaatgct catctaattg
      541 ggctgcaact gtcgtcttgc caactcccat aaatcctaat agcagcttag tcatgccata
      601 acctctctaa atccttaaaa aagtcaggat aagaagtcag gatagcttct gctcgctcta
      661 gggtgacctg tccttcttca accagtaggg ctgcaatagc tgtcatcatg ccaattctat
      721 gatctccaca ggtactgaca gctgcaccat gtaatggtgt tttgcctcta gtcaccatac
      781 cgtcctctgt cgcctgaata tcagcaccca tctgtcctaa tacatcagta acagcctgaa
      841 tgcggtcagt ttccttgacc cgtaattctt gagcgtccct gatataagtc gttccctgtg
      901 cctgagttgc cagcaaagca ataacaggca attcgtcaat caagcgagga atcaagtcac
      961 cagaaatctc aatgcccttt agggtggaat aagacacttt tagggtagca gcctgcctgt
     1021 ccttatcaac agcctgatag gagatacgac cacccatttt ttcaatgacc tctaaaagac
     1081 ctgtccgcgt aggattaatc cctacatttt cgagcacaag atctgacccc ggaacaatca
     1141 gaccagcagc taaccaaaag gctgcgctag agagatcgcc aggaatctgt aaggtctgtc
     1201 cctgcaaacg ctgcggtcct ttgatactga tttgctttcc agctactgag agctttcctc
     1261 caaattgttc aatcatctct tcggtatgat ttcttgtcaa ttccttttca aggataacag
     1321 tctctccctg tgtctgcaaa gcagctaata aaatagcaga cttgacctga gcagacgcta
     1381 caggcagctg ataatggatc ggccgcaact cctgacagcc ctttacaatt agtggtggaa
     1441 gctctttttc tccttgacca gatagctctg ctcccattag agacaatggt atggtaatac
     1501 gatccatagg acgccttgat aggctatcat ctccaagcag ctgcaccgaa aaatcctgtg
     1561 ctgctaatag ccctgcaagc aggcgcatag aagtacctga attgcccatg tctagaggct
     1621 tttgagctgg ctttaggcct ttaaaacctc ttccttcaat gattaaacta tcagctgact
     1681 cgtaaatggt gacacctagg tctcgaaagg cttgaatggt ggctaaaaca tcttgccccc
     1741 ttaaaagacc atgaatcacc gtttgcccct ctgctatagc accaaaaatg actgcacgat
     1801 ggctaattga cttgtcacct ggtaccctta gacgtcccct aagcgcctta gcttttgttt
     1861 ttaatttcat cattactcct atttttagta caccagcatt agctcagcaa agcaaataaa
     1921 agaaaatgaa gtaaggacaa gggcccttac cccatcaact aatcaccaag caccgtcttg
     1981 tttttcattc taagacaagc cgctatttct tgggcggcgc accatcattg cctaatgtct
     2041 ttttgatgag agaaacaaca ttgccgctgc gcccctctaa tttgccgatg gatagctctt
     2101 gataggtagc gttaaaaacc gcccccataa tcaatatcct tgccaggaaa ataaaccata
     2161 gcatgatgat aaaaatcatc accgaaccaa aggttttaat atcgaccatt cgctccacat
     2221 tatgcaccac ataattacca accatattgc tcaaaaaaat catgacaaag gtggtaaaaa
     2281 atgttcctgg taagatatac ctgattttct tgattttgat atttggcaac aaaaaataaa
     2341 gcaacatcag accaacaaat ataatcagta tcgtaatcgg ctgaatcagg aacaaaaaga
     2401 gcgtcgtgat gttatcattt aagtgataat gcctatccag cacctgaatc gctgccttag
     2461 aaaaggttga aaaaatcaag gcaaaggtca acaaaaacag gatcagcagg ctcgtcagca
     2521 agcctaccaa atgaccgagc aaaaagtcac gatgctcaga agcatcataa gccttattaa
     2581 aggccttttg cagagaggtt aggcttcgcg acattgtcca aagccccgtc aaggtcgcta
     2641 ctcccagcac actgcctgat ggcttagaaa aaatattaac cacaatggag gaggcagagc
     2701 gataaatatc cttaggcagc tgctccttca ttaagcgtaa taaatctgaa atatcaatat
     2761 ttaaataagg aaaaatatta gccgcaatga caatgagtgg aaaggctgtc aaaataaggt
     2821 aataagcaac tgcaatcgct gacaaatcca tctctgcact ctgaaaatgg cgcataaagg
     2881 cttggattgg ctcatattgc cattttgata tgaccttgtc caagaatttc tttattgaca
     2941 ttctaataag ttctttcttc gccctgacta gttaaaatca ctggaccatc ctttgtaatc
     3001 acaaattgat gctcatactg gcaggacaag ccaccatcaa gtgttttatg ggcccagcct
     3061 gttttcatat ctgtattaat ttcccatgtg ccagtattga tcatcggctc tacggtgagc
     3121 accatgccct ccttcagacg tagtcctctt cctgctgtac catagttagg caccatcggc
     3181 tcttcgtgca tggttggtcc aacaccatga ccaacaaggt ctcgaaccac accgtagcca
     3241 tgactttcag catattgctg gactgctgca ccaatgtcac caatgcggtt ccccacaact
     3301 gcctgctcga tcccacgata catggcttcc ttggtcacgt ccatcagcct tttgacctca
     3361 tcagacggtg tacctacagc ataagcccag caggaatcag ccaaaccacc tgtataagat
     3421 tctgtccact tcttcatttc tgccacatta tcaaaatcca aggccgctac atcaacgaca
     3481 gccttatcaa gtggctcact tagcaccata tctaccttaa gcaaatcccc ttcctgtaga
     3541 atataatggc gcggaaaagc atgtgcaacc tcatcattta gcccgcagca ggtagcgtaa
     3601 ggataatcca ttaattggcc atcaacaccg atctgtaaag gaagcacatt gtcctccttg
     3661 cagcgcctgc gcacatattc ttcgacctcc cacatgtcaa ccccaggctt aatgatctgt
     3721 ctgaggccaa tgtgaatccc agcaagaaag tctcctgctc tatccatagc ttctatttca
     3781 cgcgcagatt ttaatgttat cattgttttt gtttctcctc taattaagct tagttgtaat
     3841 aatggcttta gcaatcacct gatcatcaac catgacctcc atatcaagtg tactgcttct
     3901 tctattttca gttataattt tagggtatat cctcaattga tcatcaattt ggacagcatg
     3961 tagaaagtat atcatcattt gctcgataat gatatttttt tggtgttttt tcgttagcac
     4021 tctgacactg atttccttta agaattcagc aaccactcca tttgacagat tgccagcact
     4081 atcaatcatg gtaggctcaa tcatgacctg ataataatcc aaggtctcct caaggcttga
     4141 tagcatttgc tggctatagg tgtaaagatt tcccggctgg tgattcggca ggttttccat
     4201 agcctgtcgt ctggtaataa tccccagcag aaaatgatga tcatcaacta ctgggagcat
     4261 gttcaaatcc tcaaagatca ttttttgact aatattagcc aggctagcat tgggctttgc
     4321 agtgatagga tttggagaca tcacctgctc aagtctagtc tcagcaggct gatccaccac
     4381 atcacgcata ctgaccacac caaccacctg atcaagcgca tctacaattg gaaaccttac
     4441 ttgacctgtc tttttaatca gtgcattaaa ttcctcgaca gtgtctgtct cataaaggca
     4501 gccgtattct tcaactggaa tcagaacctg agcaactgtt tttaaatcag tcttaatgcg
     4561 aatattagac aaggcatggt taatcatcgt tgccactgta aaggtatcgt aatgtgtcac
     4621 cataaccgga ataccttggc tatcagctgt ttcaataacc tgcttagaca ccggaaagcc
     4681 acccgtcact aagatagcat tgtgattttt aagggctaac agttggatat tttcacgatc
     4741 gccaacaatc aaaagccctc ctttgatcaa ataacggtga atattttgct gggtcatcgc
     4801 tccaatagaa aacttgctaa actcatgtcc caaaccagca tgaccggcta aaacctcaga
     4861 atcactgatc cttgcaattt cggcataggt caaacggtca atacgaaccc gtcctttttt
     4921 ctcaatgcgg acagtaccac tacgcggctt ggtctcaaca atcccccgat tttcagcctc
     4981 cttgatcgct ctataggcag taccatcact aacctttaaa tgatttgaaa tacttcggac
     5041 gctcacacgc tttccaatag caagtctttc taaataatct aaaatgtctt gatgcttact
     5101 cataatgata ctcacctatc gttagttgat attctaaata atctcgtatg tgatgactat
     5161 gccgatcact gcccttaaat tgctttgtta atcgaaagcc ggctttttca gcaaccctct
     5221 ggctggcctt gttttccaga tgtgtcacaa tgatcagctg cctcaagcca aactcctgaa
     5281 aagctaaaaa ggtaagcgtc tttaagacct cggtcattaa gccctgtccc caaaagggct
     5341 gcgctaaaaa atagccaatc tcagcacttg cctgctgctt atcatatttt tctagtctaa
     5401 tagagccaag catgctatgg ctggtcttat cctctattaa ccagactccc aagggctctt
     5461 tcataaaagc attgaccatt aagaaatcac tctcagcctt ggtcatgctc tctggaaaca
     5521 caaactggta atggctgtta tgactgatca tatcataaaa cggctgatga tctgcatatt
     5581 gaaagggcct caagagcagt cgttgcgtct caacaaaagc aaaccttgct agctgtgtcc
     5641 aaatatccat agcctcccct tcaacatgcc tgtaatacta ttattatagc agatatcacc
     5701 taaacattct ataactgtca tgagttttgc catgatgatc ataataacct gacaagccat
     5761 atcatagctc aatcagactc taagctgtta aactattact aacagtcaaa accaaaaaag
     5821 agaagaccgt ctgatcttct cttgctatct tatctgctaa tgcttaaatg ggctacatca
     5881 tagaaaagtc ctatgagtaa gctcatcctt ctaaggctaa acatgcttcc ataaatacac
     5941 tgcttagtcc tgctgacgct ttgaagtcac tgctaaagca cctgcactcg ccataatggc
     6001 aagagccgct gctgtaaaga atggattagc cttctcacca gtcgttggaa gagtcttagc
     6061 cttttgctta tctttttgct tagctggtgc tgtcttagtt gctggtgtaa gcggtgtcaa
     6121 cggaagagaa gctgatggct tttctggatc agctggactc tcctctaaag cctcagtgac
     6181 tgtaaatgtc tttgtagcag cgtcataagc ccattcacca gtaacgccat tgtcattggc
     6241 atattgcctg aaggtctgct cggctgtggc tgcgtctact gccttggtag ctgtttcacc
     6301 tgagaaggta acccccttaa taacaagcct ataggtggtc aaagctggtg ttaattctgc
     6361 cgcctcaata gtctcagcta caggctgttc agtgactgta aatgtctttg tggcagcatc
     6421 ataagcccaa acgccgtcta caccattttt attagcatag tctctgaagg tctgctcagc
     6481 tacagctgcg tctactgcct tagtagctgt ttcacctgaa aaagttgctc ccttgatgac
     6541 aagcttatag ctagtcaagg ctggtgttag ttctgctgcg tcaatgacct cagaactcgg
     6601 tagagctgat aaaatctctg ccttaagcgc attgacacct tcaacagttt tggctttgtt
     6661 gattaaggtc acatagtaat cactaatgcc atactgcttt agttcattga tagcagcttc
     6721 tttagcctcc aacaaggctg ctcctgtaat gtccgcaata gctgtatgag catcattaat
     6781 ggctgcattc acttgatcaa ctgaagcagc atctgccacc ttagctgctg cagcaactag
     6841 agctagctga accttttgat cgcttttgtg ctgatcactt aaggcattga ttgttctgta
     6901 agcctcacgt cttgcttcat caagctgaac accagcaaca gctgcctttg ctttgtcaag
     6961 agctgcttta gcctgatcaa cagtatctgc agcaagtgcc tcaactccag cattagcaag
     7021 aacagcctga agctcttgat tgtcagcgta gtcatcactc agctgattga tttccctaac
     7081 agcttctcta atgaaggctg ttgtaggctc taacactgtt gctgcgtcta aagcacccac
     7141 tgaagtcgtt ccaaccagaa aggctgccga cactgaagct aaaccaacag ctgattgacg
     7201 taaaaagtag gatacctttt tgtttttttc catttttcct ccctcgcttt ttgtaaaaaa
     7261 aactttgaca ctaaaaacta ttaatgtcac ttctattata ctacgccatt ctttttaatc
     7321 aaccatttta tttaattttt ctgttaattt ttgtataatt aattttatta agctgttttt
     7381 tgat
//
LOCUS       DARYXS010000089         7352 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.090, whole genome shotgun sequence.
ACCESSION   DARYXS010000089 DARYXS010000000
VERSION     DARYXS010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7352
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.090"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            51..1364
                     /locus_tag="TV193_001619"
     CDS             51..1364
                     /locus_tag="TV193_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1513795.1"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDEFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGCNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGNLYDDERMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            1465..2352
                     /locus_tag="TV193_001620"
     CDS             1465..2352
                     /locus_tag="TV193_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1513796.1"
                     /translation="MNVNKLKMRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNY
                     TMTDFTFVGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVIS
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTL
                     YITVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAI
                     LISLISFAQFKFLGNDVEY"
     gene            2365..3195
                     /locus_tag="TV193_001621"
     CDS             2365..3195
                     /locus_tag="TV193_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1513797.1"
                     /translation="MRKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTVENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDHLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            3211..3666
                     /locus_tag="TV193_001622"
     CDS             3211..3666
                     /locus_tag="TV193_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEL1513798.1"
                     /translation="MLYDVLENIRRYKGIHRHLDVAIDFLLTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALFEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDCFCYFFPNEAHQPNGFNDDGDAVTKCLIKVLMED"
     gene            3691..4341
                     /locus_tag="TV193_001623"
     CDS             3691..4341
                     /locus_tag="TV193_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEL1513799.1"
                     /translation="MSSKKRKLMQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKMALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLFFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSPLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLY"
     gene            4370..5290
                     /locus_tag="TV193_001624"
     CDS             4370..5290
                     /locus_tag="TV193_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEL1513800.1"
                     /translation="MKTLTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAQHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINERLDIGSVR
                     SPLPELTENDLVICQQAAALIKQTKEQFCS"
     gene            5305..6189
                     /locus_tag="TV193_001625"
     CDS             5305..6189
                     /locus_tag="TV193_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1513801.1"
                     /translation="MKRYLAIDIGGTAIKYGLMTETADILEKHEIATEAHKGGPAILD
                     KVKDLVATYQEAGLAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKRVIEETFGIP
                     CDVENDVNCAGLAEAISGSAKDCPVALCLTIGTGIGGCLLIDSQVFHGSSYSACEVGY
                     IHLPDGAFQDLASTTALVRDVARRHGDAVSDWNGRRIFEEAKAGNHHCIAAIDQLVDY
                     LAQGLANICYVANPNAIVLGGGIMAQKDYLQDKILAALNNYLVPSIAEKTQLRFASHE
                     NNAGMIGAYYHFKHKEQV"
     gene            6189..6461
                     /locus_tag="TV193_001626"
                     /pseudo
     CDS             6189..6461
                     /locus_tag="TV193_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514912.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
     gene            complement(6503..7327)
                     /locus_tag="TV193_001627"
     CDS             complement(6503..7327)
                     /locus_tag="TV193_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEL1513802.1"
                     /translation="MIHNHRLISKMEAALDSMTSLEKSIAQFFMETDLKVEELTASDM
                     IKRLHVSQAALTRFAKKCGFTGYREFIFECQKSREAMDQKAPNLQNYNTKKVLMNYRE
                     LIEKATELINEKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVICEALDD
                     TDSFTWVNSSITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYQLD
                     EIVHIATARHLNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
BASE COUNT         1960 a         1440 c         1693 g         2259 t
ORIGIN      
        1 tgacatcgtc attgtctata aaaaataatt aatataaagg agaatttaca atgaaaatga
       61 agaaattagc ttcatttgtg atgcttggag catctgtttt agggttagca gcctgtggca
      121 gtagcagcaa ggaggctgac aaatcagatt cagctgctaa gacagagatc acctggtggg
      181 cctttccaac cttcactcaa gaaaaggctg atgatagcgt aggaacctac gaaaagaaaa
      241 ttattgcagc ctttgaaaag gccaatccag atattaaggt caagctagaa accattgatt
      301 tcacctctgg tccagaaaaa atcactactg cgattgaggc aggtacagca ccagatgtgc
      361 tctttgatgc tccaggtcgt atcattgagt atggtaaaaa cggtaaatta gctgacttaa
      421 atgacctgtt tactgatgag tttatcaagg acgtcaacaa cgataacatt atccaagcct
      481 ctaaagcagg agatacagct tatatgtatc ctatcagctc agcgccgttt tatatggcct
      541 taaataaaaa aatgctcaag gacgctggtg ttcttgacct tgtcaaagag ggctggacaa
      601 ccgatgattt tgaaaaggtc ttaaaagcct taaaggataa gggctgcaat cctgggtcat
      661 tctttgccaa tggtcagggt ggtgaccaag gtcctcgtgc cttctttgcc aacctctata
      721 gcagccgcat cacaaatgac gatgtgacta agtacaccac tgatgatgct aattctgtca
      781 agagcatgga gaaaatcgca agctggatta aggatggcct tctaatgaat ggctctcaat
      841 atgatggctc agctgatatt caaaactttg ctaatggtca aacctcattt acaatcctat
      901 ggtcaccagc gcaagcagga acacaggcta agctgttgga agcaagtaag gttgattatg
      961 ttgaggttcc attcccatca gaggacggca agcctgaatt agaataccta gtgaacggct
     1021 ttgcagtgtt caacaacaag gacgacaaaa agattgaagc ttctaagaaa tttatccagt
     1081 ttatcgcaga tgacaaagaa tggggtccaa aaaatgtggt tcgtacaggt gcattccctg
     1141 taagaagctc ttatggtaat ctctatgatg atgaacgcat ggcaatggtt tctaagtgga
     1201 cacaatacta ttcaccatac tacaacacta ttgatggctt tgctgagatg agaacactat
     1261 ggttcccaat ggttcaggca gtatcaaatg gagatgaaaa gcctgcagca gccctcaaag
     1321 cattcactga aaaagcaaat aaaaccatcg aaaaagcaca atagtgtgag ataaaagtgg
     1381 ctccttttca atgcacatgt ccaatggtca ctggtaagga gcctttcctt ttaggaagat
     1441 taatagaaaa agaggtatct ttgagtgaac gtcaataagt taaaaatgag agagacactc
     1501 gtttcatatg cttttttggc cccggtcttg gttttctttg tggtatttgt tttagtacca
     1561 atgattatgg gctttgttac tagctttttt aattatacga tgacagactt tacctttgtc
     1621 gggcttgata actatgtgag aatgtttcag gatcctgtgt ttataaagtc tttgattaat
     1681 acccttatta ttgtagttgg ttcagtacca attgttgttt tcttttcatt atttgtagcg
     1741 acaaaaacct acaataagca tgtgatttca cgttcgtttt accgggcggt tttcttcctg
     1801 ccagttgtga caggtagtgt tgcggtaaca gttgtttgga aatggatcta tgatcctatg
     1861 tcaggtattt tgaactatgt gctaaagtat gggcatgtta ttgagcaaaa tattagctgg
     1921 cttggggaca agcattgggc cttgctggct attattgtga ttttattaac aacctctgtt
     1981 gggcagccta ttattcttta tattgctgcg atgggaaata ttgacaattc cttagtggag
     2041 gcagctcgtg ttgacggtgc gactgaattg caggtctttt ggaaaataaa atggccaagt
     2101 ctattgccaa ccactctcta tatcacggtc atcacaacga tcaattcttt ccaatgcttt
     2161 gccttgattc agctgttgac ctctggtggt ccaaactatt caaccagcac cctgatgtac
     2221 tatctttacg aaaaagcctt caagctatcg gaatacggct atgctaacac gatgggggtt
     2281 ttcttggcta tcttgatttc actgatcagc tttgcccaat tcaaattctt gggtaatgat
     2341 gtggaatatt aaaaggagct tgacatgagg aaaaagaaat taacagcatc agatatccta
     2401 acaacagcca ttctatgttt attaacaata ttatttattt tcccctttta ttggatcatg
     2461 acaggagcct ttaaatccca gccggatact attgttgtcc caccacaatg gtggccaaag
     2521 gcacctactg ttgaaaattt taaggccttg attattcaaa atccggctct taaatggctc
     2581 tggaacagta tctatatttc tgttgccacc atgcttttgg tttgtggcac ctcttccttg
     2641 gcaggctatg ctttagcaaa aaaacggttt tatgggcaac gtttgttgtt ttcaatcttt
     2701 attgctgcta tggctctgcc taagcaggtc gtcttggtgc cattggttcg tattgtgaat
     2761 tttatgggca tccacgatac gctagcagca gttattttgc ctttggtggg ctggcctttt
     2821 ggggtattcc tgatgaagca attttcagaa aacataccaa cagagctgct ggagtctgcc
     2881 aaaattgatg gctgtggtga gattagaacc ttctttaacg ttgcttttcc aatcattaag
     2941 ccaggttttg ctgccttagc gatctttacc tttattaata cctggaatga ctactttatg
     3001 cagctagtaa tgctaacatc aagagatcat ttgacaatat ccttgggggt agccactatg
     3061 caggctgaga tggcaacaaa ctatggtttg atcatggctg gtgcagctct tgccgcagtt
     3121 ccgattgtta cagtctttct tgtgttccaa aaatccttta cccaaggtat caccatggga
     3181 gctgtcaaag gttagaaagg tcaggagatt atgctctatg atgtcttgga aaacattcgt
     3241 cgctacaagg gtatccatcg gcatttagat gtggccattg actttttatt gacaagagat
     3301 ttaaggtcac tcacagatgg caagcatgtg attttagagg ataaggtggt tctctttatt
     3361 cagcataatt gtctcaataa agaggataat gccttgtttg aataccataa gcgctatgcc
     3421 gatttgcatc tactagtcga ggggaatgag cgagtacgct atggcttagg ctacaagcag
     3481 gaggctgtta gctttgatga ggcatcagac atcggctttg tgacctgcga gaggacttat
     3541 gacttggact tgggaaatga ttgtttttgc tatttctttc ccaatgaagc tcatcagcct
     3601 aatggcttta acgacgatgg tgatgcggtc acaaaatgct tgattaaggt gttgatggaa
     3661 gattaactag aaaggatagg gagtaatgat atgagcagca aaaaaagaaa gctaatgcag
     3721 tccattttta gcttggatag caaatggctg agggctagtg ctactatctt tgaccttatc
     3781 gtgctcaatt tgctttttgt gctgtcttgc ttgcctgtgg taacgattgg cattgccaaa
     3841 atggccttgt atgctagtct gcgagattac cggcaagggg atatcggctc tgttgtaggc
     3901 gtctacggct cttatctacg gcggtttgcc aagagaggcc ttcaattagg gatcctagaa
     3961 gtgctcttga cgagctttat cttggttgac ctttatctca ttcaggctca ggtgtcgctt
     4021 ttctttcaac tatttaagat tagctgtata gcgatattat ttgtggctat tatggtcttt
     4081 ttgtatgctt atcctttagc tatgcgatat gatttgcctc ttatgtcatt atttcagcga
     4141 agctttatct tgcttagtct tttcttcccc tttagctttg cttttttagc tgttatgctg
     4201 ctagtggtct ttttgctgca gctatctccg ctaagtctat taggagggct gtcgctttta
     4261 gccattattg gcattagcag cctaacctat ccttatgtcg tcattatgga aaaccttctt
     4321 caaaaggtac aactttatta aaaataagat ttagaaaaag agtgtcatta tgaaaacttt
     4381 aaccaaatat caagggatta tccctgcctt ttatgcctgc tacgatgctg agggcaacat
     4441 cagtccagag cgtgttcgtg ctttgacaca atattatatt gataagggtg tccaagggct
     4501 ttatgtcaat ggctcatcag gcgagtgcat ttaccaaagc gttgcagacc gtaagttggt
     4561 cttagagcat gtgatggcag tagccaaggg caagctaacc attatcaatc acgttgcctg
     4621 caacaatacc aaggacagca ttgagctggc tcagcatgct gaggccttgg gggttgacgc
     4681 tattgcagcg attccaccga tttatttccg tttgccagag catgctgtgg ctgcttactg
     4741 gaatgcaatt tcagctgctg ctccaaatac tgattttgtg atttacaata ttcctcaatt
     4801 ggctggtatt gccttgaccc caagcctcta tcaggaaatg ctcaaaaatg agcgtgtcat
     4861 aggtgtcaaa aactcctcca tgcctgttca ggatattcaa acattttgtg ctatcggagg
     4921 tgatgatcac cttgtcttta atggaccgga cgagcaattt ttagggggtc gtctcatggg
     4981 ggcctccgct ggaattggcg gtacctatgg agcgatgcca gagcttttct tacgcttaaa
     5041 tcaattgatc aaggacaagg acctagagac tgctaaggcc ttgcagtacg ctatcaatga
     5101 tattattggg ttattggttt ctgcccatgg caatatgtat ggtgttatca aggaagtgct
     5161 gcgcattaat gagaggctgg atattggctc tgttcgttct cctttgccag agttaaccga
     5221 aaatgatttg gtgatctgtc agcaggctgc agccttgatt aagcagacca aggaacaatt
     5281 ttgctcttaa aatgaggtga tcaaatgaag cgttatcttg ctattgatat tggcggtaca
     5341 gccatcaaat atggccttat gacagagaca gcagacatac tggaaaagca tgaaatcgcc
     5401 actgaggctc ataagggcgg tcctgctatt ttagacaagg tcaaggacct ggttgcgacc
     5461 tatcaggagg ctggactagc tggtgttgcg atttcttcag ctggcatggt ggatcctgat
     5521 aagggcgaaa tcttttacgc agggccacaa attccgaact acgcaggcac gcagtttaaa
     5581 agggtgattg aagaaacctt tggtattccc tgtgatgttg aaaatgatgt caattgtgcc
     5641 ggtctagcag aggctatttc tggcagtgct aaggattgcc ctgtagccct ttgcttaacc
     5701 atcggtacag gaattggcgg ctgcctgctg attgattcgc aggtttttca tggcagcagc
     5761 tactctgcct gtgaggtagg ctatatccat ttgccggacg gtgcgtttca ggatttggcc
     5821 tccacaacag ctcttgttag agatgttgct agacgtcatg gagatgctgt tagcgattgg
     5881 aatggtcgtc gtatttttga agaggctaag gcaggtaacc accattgtat agcagccatt
     5941 gaccagttag ttgactatct agctcaaggg cttgccaata tctgctatgt tgctaatcca
     6001 aatgctattg tcttaggcgg tggcattatg gctcaaaagg actatttgca ggataaaatc
     6061 ctagctgccc tcaataatta tctggtacct agcatcgcag aaaaaaccca gcttcgattt
     6121 gccagccatg aaaacaatgc tggtatgatt ggggcttact accatttcaa gcataaggag
     6181 caagtctaat gatagaaacc atgtcacttg aagagatgat gtcctacagg gggcgtcacg
     6241 aggtgcccaa ggattttgat catttttggg agacctgtat caaggaaaat caagctgcct
     6301 cttatcagct tgatcaaaag gattttggcc ttgattttgc tgattgctat gagttgcgct
     6361 tcaaagggag taatggctca acgatctatg ccaaatgtgt ctttccaaaa gccaagcagc
     6421 tagtcccagt tgtcttttat tttcatggct accagggtca gtacacagct agctagggtc
     6481 attgaggtgc ttttttgtga tgctatttat ctgaaggatt gataatcgtc tcttggaaaa
     6541 tttttgtttt gccttccttg ttgatttcta aaaaataagc gtagataata tccgttacaa
     6601 agagcattgg aaattgtggg gagatacgat tgccatagtt aaggtgacga gcagtagcga
     6661 tatgcacaat ttcgtcaagc tggtaaggga tttcatcggt ctgggttgtg agcagcactg
     6721 tcttggcacc gcgtgtccca gcggtctgca aagcctctaa gacggacgct gtttgagcag
     6781 agagcgaaaa accaataacc aagcatttgt ctgtaatgct gctgttaacc caggtgaagc
     6841 tatcagtgtc atctaaggcc tcgcaaataa caccaagtcg catcagacgg agcttgaatt
     6901 ctttggcggc aagagctgag ctgcccttac cgtaaaaata aatccgctca gcattttcaa
     6961 tccattgcgc aatgtcttgt agctgctttt cattgatcag ctcggtagcc ttttcgatca
     7021 attcacggta gttcataagg acctttttag tgttgtaatt ttgcaggttg ggtgcctttt
     7081 gatccattgc ctcgcgactt ttttggcatt caaagataaa ttcgcgataa ccggtaaagc
     7141 cacatttttt ggcaaagcgt gtcaaggctg cctgtgagac atgaagcctt ttaatcatgt
     7201 ctgaagctgt tagctcttcg acctttaggt ctgtttccat aaaaaattga gcgatgcttt
     7261 tttctaagct cgtcatgctg tctagtgcag cttccatttt gctgattaaa cggtgattgt
     7321 gtatcatatg aactccctga tgtaaggctg tc
//
LOCUS       DARYXS010000090         6969 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.091, whole genome shotgun sequence.
ACCESSION   DARYXS010000090 DARYXS010000000
VERSION     DARYXS010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6969
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.091"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            184..1419
                     /gene="arcA"
                     /locus_tag="TV193_001628"
     CDS             184..1419
                     /gene="arcA"
                     /locus_tag="TV193_001628"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEL1513803.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGVEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMSIEDNQELIEKTMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYENEELRIVEETGDLAELLAANLGVERVEL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            1429..1860
                     /locus_tag="TV193_001629"
     CDS             1429..1860
                     /locus_tag="TV193_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1513804.1"
                     /translation="MTRVIVGNQPFQRAASLYIRYQVFVLERQIDRQDEFDCFDDNDR
                     VYAVLYDGDQPVSTARFLPTAKDQARLTRVATLRQYRGRGYGAQVIEALEQYAREQAY
                     ERLVIHSEISAQSFYEGLGYQAFGEPYDEDGEPCQSVEKYL"
     gene            1875..2888
                     /gene="argF"
                     /locus_tag="TV193_001630"
     CDS             1875..2888
                     /gene="argF"
                     /locus_tag="TV193_001630"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEL1513805.1"
                     /translation="MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNA
                     DEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKAANDNLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            3050..4543
                     /locus_tag="TV193_001631"
     CDS             3050..4543
                     /locus_tag="TV193_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEL1513806.1"
                     /translation="MTEEKKRGFKIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKDGG
                     VISGTYQTVKSNPQGFFDILMAPVRGMLGVKGTEGAIQVSFFILMVGGFLRVVNKTGA
                     LDTGIASVVRKNKGREKLLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRIIQWVVLVGMSIWFV
                     YSYASKIEKDPSKSLVADKAEEHKEFFQLQNSGEDLTSRQRKVLAIFTLTFVIMILSL
                     IPWEDFDIQLFTNINTWLTTTPVLGGIIGKTMGAFGTWYFPEITMLFIMMGVLVAVVY
                     RMSEDDFFSAFLSGAGEFLGVAIICAVARGIQVIMNGGMITATILHWGETGLAGLSSQ
                     IFVVLAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRIDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            4560..5891
                     /locus_tag="TV193_001632"
     CDS             4560..5891
                     /locus_tag="TV193_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEL1513807.1"
                     /translation="METYIQPRHQEACVAAIKKIVSYPSVLNEGENDTPFGQAIQDVL
                     EATLALCQDLGFNTYIDPKGYYGYAELGDQTEVLAILCHLDVVPAGDLKLWHKDPFTC
                     IEKDGCLYGRGTQDDKGPSMMALFATKALMDAGVVFNKRIRFIFGTDEETLWRCMNRY
                     NEVEEEATFGFAPDSSFPLTYAEKGLLQAKLVGKGSPKLNLEVGQAYNVVPARASYQG
                     DKLEALKEELDRLGFEYVVKDDELTVYGLAQHAKDAPDGINALIRLAKALVVLEPEPV
                     LDFLAHVVDEDGRAVNIFGPVQDEPSGGLSFNVAGLTLTKEMTEIRLDIRIPVLADKD
                     TLVDQLSQKAQDYGLAYEEFDYLAPLYVPLDSELVTTLLEVYRKKTGDQSPAQSSGGA
                     TFARTMANCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            5909..6859
                     /gene="arcC"
                     /locus_tag="TV193_001633"
     CDS             5909..6859
                     /gene="arcC"
                     /locus_tag="TV193_001633"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEL1513808.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALVSTSKSLVKLIKEGH
                     EVIITHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GITKEVAAVVTQVIVDENDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPIGIKEANVIRSLVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLP
                     KVEAAIAFVENKSNAKAIITSLENIDNVLSANAGTQIIAG"
BASE COUNT         1970 a         1335 c         1648 g         2016 t
ORIGIN      
        1 aaacaagaaa acgtatacaa aaacataaac attcattttc aggcgaaaaa gtgtaatcgt
       61 ttacacagat tggctgtgag aaatacccta tttttgaatg ctgcttggag taaactaggg
      121 gtgtaagcaa aagctaagag tcttagcagt gaattcacaa aacattagaa agaggtaatt
      181 cttatgactg ctcaaacacc gattcatgtt tactctgaaa ttggcaagct gaaaaaggtt
      241 ttgctccata ggcctggcaa ggaaattgaa aacctgatgc cagactactt ggaacgtcta
      301 ttatttgacg atattccatt tttggaggac gctcaaaaag agcatgatgc ttttgcacaa
      361 gcattacgag atgaaggcgt agaggtgcta taccttgaaa cactagctgc tgaatcactt
      421 gtaacaccag aaattcgtga agccttcatt gatgaatacc taagcgaagc taatattcgt
      481 ggaagggcaa ctaaaaaagc tattcgtgag ctactgatgt ctattgaaga caatcaggaa
      541 ttgattgaaa aaacaatggc aggtgtgcaa aaatcagaat tgcctgagat tccagcagca
      601 gaaaaaggct tgactgactt ggttgaatca agctatcctt ttgcgattga cccaatgcca
      661 aacctttatt tcacacgtga tccgtttgca actattggta caggtgtttc gcttaaccac
      721 atgttctcag aaacacgcaa tcgtgaaaca atctatggta agtacatttt cacacatcac
      781 ccaatctacg gtggcggcaa ggtacctatg gtttatgacc gtaacgaaac cactcgtatc
      841 gagggtggag atgagctggt tctttcaaaa gatgtgcttg cagtaggtat ctcacagcgg
      901 acagacgcag catcaattga aaagctcttg gttaacatct ttaaacaaaa tcttggcttc
      961 aagaaggttt tggcctttga atttgctaac aatcgtaaat tcatgcacct agataccgtc
     1021 tttacaatgg tggattatga taagttcacg attcacccag aaatcgaagg agatcttcgc
     1081 gtttactcag tgacctatga aaatgaagag cttcgtattg tagaagaaac tggtgatttg
     1141 gctgagcttt tagctgctaa tctgggagtt gagcgtgttg agcttattcg ctgtggtggt
     1201 gataaccttg tggcagctgg tcgtgagcaa tggaacgacg gctcaaacac gctaacaatc
     1261 gcaccaggtg tcgtggttgt ttataaccgt aacactatta cgaatgccat tcttgaatca
     1321 aagggcttga agctcattaa gattcatgga agtgaattgg ttcgcggtcg tggtggacct
     1381 cgttgcatgt caatgccgtt tgaacgtgaa gacatctagg agaggcaaat gacaagggtt
     1441 attgttggaa atcagccttt tcaacgggca gctagcttat atattcgcta tcaggttttt
     1501 gtcttagaac ggcagattga tcggcaagat gaatttgatt gcttcgacga taacgatcgc
     1561 gtgtatgcag tcttgtatga tggtgatcag cctgtatcca cagctcgctt tttacccaca
     1621 gctaaagatc aggctcgtct aacaagagtt gctacgctgc gtcagtatcg tggtaggggc
     1681 tatggtgcgc aggtgataga agcgcttgag cagtatgcca gagagcaagc ttacgagcga
     1741 ttggttattc atagcgagat tagcgcacag tcattttatg aaggtcttgg ctatcaagcc
     1801 tttggcgagc cttatgatga agacggtgag ccttgtcaat cagtagaaaa atatttataa
     1861 aaaggagaat ttaaatgaca caagtatttc aaggacgtag cttcttagca gaaaaagact
     1921 ttacacgtga ggaatttgaa tacctcattg attttgcagc acacttgaaa gaccttaaaa
     1981 agcgtggtat tccacatcac tatttagaag gtaaaaatat tgccctcttg tttgaaaaaa
     2041 catcaacgcg cacacgtgct gcctttacaa ctgcggcgat tgatttagga gctcatcctg
     2101 aataccttgg cgctaacgat attcagcttg gtaaaaagga atcaacagag gacacagcta
     2161 aggtattggg tcgtatgttt gatgggattg aattccgtgg ctttagccaa cgtatggttg
     2221 aagaattggc agaattctca ggtgttccag tgtggaatgg cttgactgat gaatggcacc
     2281 caacccaaat gcttgcggac taccttactg tcaaggaaaa ctttggtaag cttgaaggct
     2341 tgaccttggt ttactgtggt gatggacgca acaacgttgc taattcactg ttagtagcag
     2401 gtaccttact aggtgtgaat gttcatatct tctcaccaaa agagctcttc ccagcagaag
     2461 acatcgtgaa gctggctgag ggctatgcta aagcatcagg tgcgcatgtg ttagttactg
     2521 acaatgctga tgaggctgta aagggcgcag atgtgcttta cactgatgtg tgggtgtcaa
     2581 tgggtgaaga agacaagttt gaagagcgtg tgaagctctt gaagccatat caagtgaaca
     2641 tggagcttgt taaaaaagcc gccaacgaca accttatctt cttacattgc ttgccagcct
     2701 tccatgacac aaatactgtt tacggaaaag acgttgctga gaaatttggt gtagaagaaa
     2761 tggaagtaac agatgaggtc ttccgcagca aatacgctcg tcactttgac caagcagaaa
     2821 accgtatgca cactattaaa gcggttatgg ccgcaactct tggtaatctt ttcattccaa
     2881 aagtgtaagc tgtgattggt accttttaat ttattttagc tcatttcatt aatttaacat
     2941 ttaactacta aaaaacgtac tttaactaca tgacgagtcg ttctggttct cgtgtccttg
     3001 accggaactg ggacggctta tttttatgaa aaggtaagag gtaatcacta tgacagaaga
     3061 aaaaaaacga ggttttaaaa ttccttcttc ttacactgtt ttgtttatca tcattgctat
     3121 tatggcagta ttaacctggt ttattccagc tggtgcttat gagactgcta aggatggcgg
     3181 tgtgatttca gggacctacc aaacggttaa gtcaaaccct cagggctttt ttgacatttt
     3241 aatggcacct gttcgaggca tgctaggtgt caaagggact gaaggggcaa ttcaggtttc
     3301 tttctttatt ttgatggttg gtggcttttt aagggttgtc aacaagacag gtgcgcttga
     3361 tacagggatt gcttctgttg tgcgtaaaaa taagggtaga gaaaagctgc ttattgcgat
     3421 tttgattcct ttgtttgcac ttggtggcac aacctacgga atgggagaag aaacaatggc
     3481 gttttaccct cttcttattc cggtaatgat tgcggttggc tttgatagca ttgttgcagt
     3541 agctattatc ctgattggtt cacagattgg ctgtttggcc tcaaccatca atccctttgc
     3601 tactggagtg gcagcagatg cagccggtgt tagtatcgca gatggtatga tttggcggat
     3661 tatccaatgg gttgtccttg ttggtatgtc tatctggttt gtttacagtt acgctagcaa
     3721 gattgaaaaa gacccaagca agtccttggt tgctgacaaa gctgaagaac ataaggaatt
     3781 cttccagctg caaaattccg gtgaggattt gactagtcgt caacgaaagg ttttagccat
     3841 ttttaccttg acatttgtca tcatgattct tagcttgatt ccttgggaag attttgacat
     3901 tcaattattt acaaatatca acacttggct aacaacaaca cctgttttag gtggtattat
     3961 tggtaaaaca atgggagcct ttggtacttg gtatttccca gaaattacca tgctctttat
     4021 catgatgggt gttttagtgg ctgttgttta tcgcatgagt gaagatgact tcttctcagc
     4081 ctttctaagt ggtgcaggtg agttcctcgg tgttgcgatt atttgtgcgg tagcgcgtgg
     4141 tatccaagtg atcatgaatg gtggtatgat tacagcaacc attcttcatt ggggtgaaac
     4201 aggtcttgca ggcttgtcat cacagatctt tgttgtcttg gcctatattt tctatttgcc
     4261 aatgtccttc ttgattccat caacatcagg acttgccggt gcaacaatgg gaatcatggc
     4321 tccgcttgga caattctcaa atgttcctgc tcatttggtt atcacagcct tccaatcagc
     4381 atcaggtatc ttaaacatga tttcaccaac ctctgctatt gttatgggag cgctcgcact
     4441 tggacgtatt gatctaggta cttggtggaa atttatcggc aagtttatcg ttatggtaat
     4501 gcttgttagt gttttgttgt tagtagtagc gacattcttt taagagatag gaggctccta
     4561 tggaaaccta tatccaacca agacaccaag aggcttgtgt agccgcgatt aaaaaaatag
     4621 tatcttaccc ttctgtgcta aatgaggggg aaaatgacac accctttggc caagccattc
     4681 aagatgttct tgaagcaacc ttagccctgt gccaagatct tggttttaat acctatattg
     4741 atcctaaagg ctattatggc tatgctgaat tgggcgatca aacagaggtg cttgctatcc
     4801 tttgtcactt agatgtggtg cctgctggtg atttgaagct gtggcataaa gatcccttta
     4861 cttgtattga aaaagatggc tgcttgtatg gacgtggcac tcaagatgac aaggggccat
     4921 cgatgatggc actctttgcc actaaagcac ttatggacgc tggtgtggtc tttaacaaac
     4981 gcattcgctt tatctttgga acagacgaag aaaccctctg gcgctgtatg aaccgttata
     5041 atgaagtaga ggaggaggca acctttggtt ttgccccaga ctcaagcttc ccattgacct
     5101 atgctgaaaa ggggctttta caagctaagc tagttggtaa gggatcgcct aaactcaatc
     5161 ttgaggtggg tcaggcctat aatgtcgttc cagctagagc ctcttatcag ggagacaagt
     5221 tggaggcatt aaaggaagag cttgacaggc ttggctttga atatgttgtc aaagatgacg
     5281 agctaaccgt ctatggactt gctcagcatg ccaaggacgc tccagatggg attaatgccc
     5341 ttatcaggct tgcaaaggct cttgtagtgc ttgagccaga gccagtcctt gactttcttg
     5401 ctcatgtggt tgatgaagac ggcagagcag tcaatatttt tggtccagtt caggacgagc
     5461 catcaggagg gcttagcttc aacgtagctg gtcttacctt aacaaaagag atgacagaga
     5521 ttcgtttgga cattcggatt ccggtcttag cagataaaga taccttagta gaccagttaa
     5581 gccaaaaagc gcaggactac ggtctagctt acgaggaatt tgattatttg gcacccttat
     5641 atgtgccctt ggacagcgag ctagtaacta ccctgttaga ggtatatcgt aaaaaaacag
     5701 gggaccaatc gccagcccaa tcatcaggtg gagcaacctt tgctcgtaca atggctaatt
     5761 gtgtggcctt tggagcatta tttcctgatg ctgttcaaac agaacaccaa gaaaatgaac
     5821 atatcgtctt agcagatgcc tatcgtgcaa tggatattta cgcggaagcc atctaccgac
     5881 taacacgata agatgaggag tatcatatat gacaaaacaa aaaattgttg tcgcacttgg
     5941 aggaaatgca atcctctcaa cagacgcgtc agctaaggca caacaagagg ccttggtttc
     6001 gacatcaaaa tcactagtga agttaatcaa agaaggccat gaggtgatta tcacgcatgg
     6061 caatggtccg caggttggta atctcttatt gcagcaggca gcagctgatt ctgagaaaaa
     6121 tccagccatg ccattagata cctgcgttgc catgacagaa ggcagcattg gcttttggtt
     6181 agtcaacgcc ctagacaatg agctgcaagc ccaaggcatc acaaaggaag tggcagcagt
     6241 tgtcacccag gtcattgttg atgaaaatga ccctgccttt aaaaatccga ctaaaccaat
     6301 tggtcctttc ttaaccgaag aagacgctaa aaagcaaatg gcagaatcag gtgctagctt
     6361 taaggaggac gctggtcgtg gctggcgtaa ggtggtgcca tcaccaaagc caattggtat
     6421 caaagaagct aatgtgatta gaagcttagt tgattctggt gttgtggtgg tcagtgctgg
     6481 tggtggcggt gtgccagttg ttaaagaccc tgcaagtaaa acgcttaccg gtgtggaagc
     6541 tgttattgat aaagactttg ctagccaaac cctttcagaa ttggttgacg ctgatctctt
     6601 tattgtcttg acaggtgttg ataatgtcta tgttaacttt aacaagcctg atcaaagaaa
     6661 attggaagag gtaacggttt ctcaaatgaa ggaatacatc gctcaggacc aatttgctcc
     6721 cggaagcatg ctgcctaagg tggaggctgc aattgctttt gtggaaaaca aatcaaatgc
     6781 caaagctatc atcacatcgt tagaaaatat tgacaatgtt ctctcagcaa atgctggtac
     6841 acaaattatc gcaggctaat tcagatgact gcacaatgag cttaggcttt tgtgctttga
     6901 taggttttag ctgataagct tgaaaaattg atttaaaagg ttaaattagg ttaatttagc
     6961 cttttcttt
//
LOCUS       DARYXS010000091         6885 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.092, whole genome shotgun sequence.
ACCESSION   DARYXS010000091 DARYXS010000000
VERSION     DARYXS010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6885
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.092"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(25..486)
                     /locus_tag="TV193_001634"
     CDS             complement(25..486)
                     /locus_tag="TV193_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEL1513809.1"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVAYVQHDVPQIILGGAVEP"
     gene            complement(530..1606)
                     /locus_tag="TV193_001635"
     CDS             complement(530..1606)
                     /locus_tag="TV193_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1513810.1"
                     /translation="MSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSAT
                     VFISPKRRVFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVS
                     FSFSQSLQAAFSEVTLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKP
                     GQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDF
                     GCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKAGAGMTYREFDAIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIE
                     DDLVITETGCQVLTKAPKELIVLT"
     gene            complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TV193_001636"
     CDS             complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TV193_001636"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEL1513811.1"
                     /translation="MQDKLIIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETNSDYT
                     RNVMRGYMNELTCASCHGYRLNDQALCVRVGGEYGLTIGQVSELSIADHLQLLDRLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRYIDIKGAAQNNL
                     QNLDVRFPLEKFIAVTGVSGSGKSTLVNSILKKAVAQRLNRNSEKPGKHRSITGIDHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVATGTPEEVAAVEESYTGQYLKLKL"
     gene            4915..5859
                     /locus_tag="TV193_001637"
     CDS             4915..5859
                     /locus_tag="TV193_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEL1513812.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLATLLSSFVVIYFIRKKWF"
     gene            complement(5884..6021)
                     /locus_tag="TV193_001638"
     CDS             complement(5884..6021)
                     /locus_tag="TV193_001638"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513813.1"
                     /translation="MAADMLRLIIRSSSSSYRYLLGRLFALAVVVPALADELSTGRAQ
                     E"
     gene            6118..6768
                     /locus_tag="TV193_001639"
     CDS             6118..6768
                     /locus_tag="TV193_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HEL1513814.1"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDDDIKALLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNTTVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYSATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMAPQR"
BASE COUNT         1997 a         1792 c         1335 g         1761 t
ORIGIN      
        1 ttatgaccat tatcagcctt cggcctaagg ctcaacagcg ccacccaaga taatctgagg
       61 cacatcatgc tgaacataag caaccccttt tttatccatt agctcaatgg caaaagggtg
      121 gggacgataa tgggatttat aggtgatctt gcaaataccg gcctgaagga gggccttagt
      181 gcaattgata caaggaaagt gcgtgacata aatctctgtt ccagcagttg aaatgccctc
      241 cttagcacat tgaatcaaag cattcatctc tgcatgaaca gttctgatac aatgcccttc
      301 ttccatataa tgaccggctt cattacagtt atcagtcgcc gacacgccac cgttatagcc
      361 tgtcgcaata atgcgattgt ccttgaccaa gactgcaccg acaaatgctc gatcgcaggt
      421 tgatcgctta gatatcagct ctgcatttgc cataaaataa tcttgccatg atagcctatc
      481 tgtcatgctt tgtctcctaa tcccttctaa ctcacagcag ctaacaagcc tacgttaaaa
      541 caatcaattc ctttggtgcc ttggttaaga cctgacagcc tgtttctgtg atgacaagat
      601 cgtcctcaat acgcacaccg tatttgccgt ctaaatagat acccggttca tctgtcacca
      661 ccataccagc tagaagcctt tgatctgtct tagcaaaaaa tggatcctca tgaatatcaa
      721 gtccgatccc atgaccaatg ccatgtgtaa agtgactgcc atatcctgcc tcagtaatga
      781 gctgacgagg aatagcatca aactcacgat aggtcatgcc tgcaccagcc tttgcaatca
      841 aagcctgatt agctgcaaga accagctcat aaatctcacg ctcctggtct gtcacctgtc
      901 cgatatgaat agtccttgtc atatcactca cataatgctg ataataacag ccaaagtcaa
      961 gcgtcaaagt ctctccctgc tgaatgattt tatctgtagc acgaccatga ggcatggcag
     1021 aacgatagcc tgaggctgca atggtgtcaa aggaaatgcc tgaggcaccg tattgacgca
     1081 tgcgaaaatc caagaaatta gccacttcaa gctcacttgt ctgccccggc ttaataaagt
     1141 ccaagacatc acagaaggcc ttgtctgaaa tcgagcaggc tttagcaata atgtcaatct
     1201 cagaagcgtc cttaatcaga cgaagcgctt caataaagcc tgattgcggc agcaaagtca
     1261 cctctgaaaa ggctgcctga aggctttgag aaaaggaaaa ggacacctga tcctcaaagg
     1321 ctagactgct aagcttgtcc gcctgtagga ttgcagcaat ttcagccagc ggtgtgcggc
     1381 tctcaatgat atcaaagccc tcaatactag ccttagcaat taaggtataa cgcgaatctg
     1441 taataaaaac acgccgcttt ggactgataa agaccgtagc tgaggtccct gaaaagcctg
     1501 tcaggtaata aatattagtc agattagtaa ttaaaatagc ctccaagcct tttttttcca
     1561 gtaatgcttg gcaattgctt aagcgctgtg ctaaaaatga tgacatggta atctccttta
     1621 tcgacaaaac taccttaagt ttaccatgat ttcaacgctt ttaaaagcaa gacccattaa
     1681 agacagccaa caaaaaaagc atttctgaca gtggaccaaa aggctaatca gcttagccgc
     1741 cactaccaaa aatacccttt aaatatcacc cacgcccccc gcgaagagag ctactggcta
     1801 tctattattt aaattaaaat cacccctcat ttcaatccat gccctatcat cgttcatacg
     1861 aagatcactc tgtcaattga tgtcaggcct gcaactttac aatttcagct tcaggtactg
     1921 ccctgtgtag ctttcctcaa cagcggcaac ctcttcagga gtcccagttg caaccagttg
     1981 acctccacca acaccgcctt ctggaccaag gtcaataata tggtctgccg acttgatgac
     2041 atctaaattg tgctcaatca ctaaaacagt attgccatca tcaacaaagc gctctaaaac
     2101 cttcagtaat cgcgcaatgt catctgtatg cagccccgtc gttggctcat ctaaaatata
     2161 caagctttta ccagttgaac gcttgtgcaa ttcactagcc agcttcatgc gctgggcctc
     2221 gccacctgat agggttgtcg ctggctgccc tagagtaaca tagccaagcc caacgtcctt
     2281 aatggtctga attttacgag caatctttgg aatagctgag aaaaatacca gagcatcatc
     2341 taccgtcata tccaagattt cagcaatgtt tttgccctta taatggacct ccaacgtctc
     2401 tgaattatag cgtctgccat gacaaacatc acatggaacg taaacatctg gtaaaaaatg
     2461 catctcaatc ttgataatcc catctccaga gcaggcttca cagcggcctc ccttcacatt
     2521 aaaggagaag cgcccttttt tgtagccacg aatcttggct tcattagtct gggcaaagag
     2581 ctctcgaata tcatcaaaaa caccggtata ggtggcagga ttagagcgcg gtgtccgccc
     2641 aattgggctt tgatcaatat caatcaaccg ttccaaatgg tcaatgccag tgatagacct
     2701 atgcttgcct ggcttttcag agttacggtt tagcctttga gccactgctt ttttgagaat
     2761 gctattaacc agcgttgatt ttcctgagcc agagacccca gtcactgcaa taaatttctc
     2821 cagaggaaac ctcacatcaa gattctgcag attgttttgg gctgctccct tgatatcaat
     2881 atagcgacca ttgccagcac gtcgctccaa aggaacgggt attgatttgc gtccagacag
     2941 gtattgacca gtgatagacc ttttatgccg agcaacctgc tgaggcgttc cagaggcaac
     3001 aatctgcccg ccaaagtccc cagcaccagg tcccacatca atcagccaat ctgcctgcat
     3061 catggtatcc tcatcgtgct caaccacaat caaggtattt cccaagtcac gcattttttt
     3121 caagctatca atcaagcgat cgttatctcg ctggtgcaga ccaatagaag gctcgtccaa
     3181 aacgtaaagg acacctgaca gattagagcc aatttgcgtt gccaaacgga tacgctgact
     3241 ctctccacca gacaaggtgc ctgccgagcg agacaaggtc agataattca gaccgacatt
     3301 attcaaaaag gtcagccgat catgaatttc cttgataatt ggctttgcaa tggtgctttc
     3361 attgtctgac agctcaagcc gatctagcag ctgcagatgg tctgcaatag atagctctga
     3421 cacctgaccg atcgtcaagc catactcacc accaacacgc acacacaggg cttgatcatt
     3481 gaggcgatag ccatgacagc tcgcacaggt caattcgttc atatagcctc gcatgacatt
     3541 gcgggtatag tcactgttag tctcatggta gcgacggtta atatttgtca caaccccttc
     3601 aaagggaata tcaatgctgc gctcgccacc aaaatcattg acatagtgaa aatggaactc
     3661 ctgatcacct gagccataca ggatcagctc cttttcctgc tcgctcaatt gctcaaaagg
     3721 cttgtccata tcaacaccaa agctctgcat tgcctgctca agcatggttg ggtaataatt
     3781 tgacgagata ggattccaag gagcaagagc cccctctctc aaggtcttgc tgggatcagg
     3841 aacaactaga tccaaatcca cctccagctt gatccctaag ccatcacagg tagggcaaga
     3901 gccaaagggc gcgttaaatg aaaaaagacg aggctctagc tctggcactg taaaaccaca
     3961 taccggacag gaataatact ctgaaaacag caactcattg ccgtccatcg tatcaatcat
     4021 cagatagcca tctcccaagc gaagcgcagc ctctatcgaa tcaaaaagac gactgcggat
     4081 cccgtcctta ttgaccaagc gatcaatgac gacctctata ttgtgcattt tgcttttgga
     4141 taatgctggt acctctgaca catcaaaaat ctctccatca acacgcacgc gcacataacc
     4201 gtccttttga attttctcaa acactgtctt gtgctgaccc tttttacgac ggacaagagg
     4261 cgccaaaatc tgcatacgcg tccgctcagg caactctagc acctgctcaa caatctgctc
     4321 caccgaggaa gccgtaatag ccccatgccc attgatacaa tagggagtcc ccacacgcgc
     4381 ataaagaagc ctgaggtaat cattgatttc tgtcaccgta ccaacggttg atctaggatt
     4441 cttgctggtt gttttttggt caatagaaat agcaggacta agcccgtcta tagaatccac
     4501 atcaggcttt tccatgttgc ctaaaaattg cctagcatag gctgacaggc tctccacata
     4561 gcgacgttgt ccctcagcat agatggtatc aaaggcaagg ctagattttc cagatcctga
     4621 taagccggtc accacaacga gcttatcacg tggaatctcc acatcaatat tttttaaatt
     4681 gtgggcacgc gccccacgaa taatcaattt atcttgcatg ctcttgtgcc cccaggcacc
     4741 ctcctcatcg agatttattc cattataaca aaaatttcta ataatcagtt gccccaaaca
     4801 ccatgaattt gtagtataat agacaggtat tgagtgtttt tcaaaaaggc ttcgtctacc
     4861 tgatgacaag aagctcactt caatactgac taatcacaaa aaggagggct tgtcatgaaa
     4921 caaatgtttc tttcatcggc aattgaattc aaagaaatcg aaacattcga gccaggtgct
     4981 tggatcaaat tggtcaaccc ctcccaggaa gagtctatcg ccattgccga tcaatttaac
     5041 attgatattt ctgacctgcg tgcccctttg gacgttgaag aaacctcacg tattgctgtt
     5101 gaggacgact acaccttgat tatcgtcgac gttccggtct atgaggagcg caacaacaaa
     5161 agctactatg tgaccatgcc tttgggaatt atcgtcactg aaagcgcggt aatcaccacc
     5221 tgcctgcatg acatgacact ttttgatcag tttcataagc gtaaggttaa aaacttttac
     5281 acctttatga agacacgttt tgtctttcaa attctctacc gcaatgccga gcttttccta
     5341 accgcactaa gaacaattga ccgacaaagc gaacgcttgg aggctcagct tgaggcagca
     5401 acccgaaacg aagaattaat cgacatgatg gagcttgaaa aatccatcgt ctacctaaag
     5461 gcctccctaa agttcaacga gcgcattgtc aaaaaattat ccagctcaac cagctcactc
     5521 aaaaaatata ttgaggacga ggacctgctt gaggatacac tgattgagac ccaacaggct
     5581 attgagatgg ctggcattta tgaaaatgtc ttaaatgcca tgaccgaaac aaccgcctca
     5641 atcattaaca acaatcagaa caccatcatg aaaacattgg ctctgatgac gatggctcta
     5701 gatattccga cagtgatctt ctcagcctac ggcatgaact ttcaggataa ttggctgccg
     5761 ctcaatggcc ttagccatgc cttctggtat attgtcctgc tggcaaccct gctcagcagc
     5821 tttgttgtta tttattttat tagaaaaaaa tggttttaat aaccccattt ccaactgaaa
     5881 aagctactcc tgagctctac ctgtagacag ctcatcagct aaagcaggca ctactactgc
     5941 taaagcaaac aatcgtccca gcaagtaacg gtagctacta ctgcttgatc gtatgatcaa
     6001 gcgcaacata tcagctgcca tactagctgg caaagcaagc cagcaaggcg cccttgaggc
     6061 attatcccag gctagccctg cttacaatca tcacatcata taggagaatc ccctgtcatg
     6121 gacttacaac agcttaccaa aaaaaatcaa gaatttattc atatcgccac caatcagctc
     6181 atcaaagatg gcaaaactga tgacgacatc aaggcacttc ttgaggaggt cattccgacc
     6241 atcttagaga accagaaaaa aggcatcact gcaagaagcc tatacggggc tccaactgcc
     6301 tgggcagctt cctttagtaa agaagcaaat caaaaagaag ccacacccaa aaacaccaat
     6361 ccatggctga tgtggcttga tacctcgctt ctatttatcg gtattgttgg ccttttaaac
     6421 agtatcatga ccttctttaa taccaacact accgttaccg ggcttgtgtc cttgcttgct
     6481 cttggctttg gagggggtgc ttccatgtac gccacctact attttgttta tcgccatatg
     6541 ggcaaggaca agagccttcg tccaagctgg tttaaggtta ttggtgctct gacacttgca
     6601 atgctggcct ggataaccct ctattctgct acagcctttt taccaaaggc gctcaaccca
     6661 caattacctc ctgtagcact tctcattacc ggtgccttag ctatcggact gcgttacctc
     6721 ttgcagcgca aatacaatat ccaaaacact atggcaccgc agcgctagca gcagctccac
     6781 tgcctgagga agcacttccc tattctctct tgagggcagt tagccttttc ataccatatt
     6841 gctggcaaca ccagacactg atctacaatc gacactcctc aatcc
//
LOCUS       DARYXS010000092         6877 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.093, whole genome shotgun sequence.
ACCESSION   DARYXS010000092 DARYXS010000000
VERSION     DARYXS010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6877
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.093"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            116..328
                     /locus_tag="TV193_001640"
     CDS             116..328
                     /locus_tag="TV193_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL1513815.1"
                     /translation="MSQQHRKWSALVEQRLKEKDWTKGDLALAVGLRSSGTITDLLAK
                     GKGSVDLKVRVSKILGIREPWELFER"
     gene            401..652
                     /locus_tag="TV193_001641"
     CDS             401..652
                     /locus_tag="TV193_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513816.1"
                     /translation="MDNILMSLSDWIKEIIEKTVNRLVQIKLDEANAELLTREKVADR
                     LNMSPATFDKYYRYDKNFPSELPGVRWKKAEIIAWLNNK"
     gene            928..1269
                     /locus_tag="TV193_001642"
     CDS             928..1269
                     /locus_tag="TV193_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513817.1"
                     /translation="MTQAERIREFYKENPTASYDEVAEAIGTTNSNVRANIAKDIKAG
                     RCVRLEDKSLDYSAHFGATEALADLVDWKNDTRREWVEMLTRAAEKETDSNTMRLLIK
                     EANKLMKEVTK"
     gene            1269..1751
                     /locus_tag="TV193_001643"
     CDS             1269..1751
                     /locus_tag="TV193_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEL1513818.1"
                     /translation="MAKLYELVGEYRDLYELNLDDETLKDTLDSIDWADRLSEKVEGY
                     AQVIETALAEAKMFEEAEKKFKAKKEAAKKKAAWLQGNVFDAMKLTNQTEIKSGIFTV
                     RIKQNPESVKVDEELLPKKYFNKKITVAPDKTTLKELLKSGKKIKGAELIRTEKLVIK
                     "
     gene            1748..2221
                     /locus_tag="TV193_001644"
     CDS             1748..2221
                     /locus_tag="TV193_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513819.1"
                     /translation="MMILAIDPSSNRIETSTTGIVLLDNARLVDYWVVPFGAENFKKW
                     FKDIGRTLEFDTVVVEKFEVRDNDYSRDNSVVETISAIELCYPDLVLQRNAGYQTDIP
                     NGLLKALGLWSFDKSHHNDVRAAARLGLFWAQRNDIEEVIVDIGNRITQMASGSS"
     gene            2181..3356
                     /locus_tag="TV193_001645"
     CDS             2181..3356
                     /locus_tag="TV193_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513820.1"
                     /translation="MAIELRKWQAEAVKRSDRDCPGIFLEAYGGRGKTICAFEIAKHK
                     EAKKVLVINNRLAILNGWNNTHQDLGYVNDFELEIMTDRRLQNRLASGESIECDVFVI
                     DEWQNMSSDANVKAYKKVKRGYTVGLSATPIRKKGQNFYPLEKTIFGMAEPNQRENWQ
                     LAHGKMKYSKFSYSKQEWDDFRNYESYVANLPNFFRWEDVEAIEEAEENNGFEVIFEP
                     VWCPPANPKELEQFRSLNIVGKDGKFAMAKQTFGRKIFERYLIQTGFEIDFPKLKAIN
                     ADTPMLIQLDLLLASHTEMLIVSKSKQIVEVIRERHPEIGIWTGDKKDALEQTNVVAT
                     TQVLGVGVDGLQYKFKTIVVLDPVNPSDGDYDDYRQLLWRVTGSRQQHDVRVIEFYF"
     gene            3366..4076
                     /locus_tag="TV193_001646"
     CDS             3366..4076
                     /locus_tag="TV193_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEL1513821.1"
                     /translation="MAEHKESGIFIVLRCIQADLIAPKGQYNSFGKYAYRSAEDILEA
                     LKPLLKKYDASIVLSDEIVQVGERYYVEATATLYAMGECVGNKAYAREDETKKGMDGA
                     QITGAASSYARKYALNGLLAIDDNNDADTDAYHNQNNQSAGKTQKTNQKQASQQESTA
                     KAPAKNNGSKTITGAQAKAIRTELKNMAEATGSPAAAIGNWFIGKMGVDKPENIPAER
                     LKEAQQIIADAKKVKGIE"
     gene            4077..4469
                     /gene="ssb"
                     /locus_tag="TV193_001647"
     CDS             4077..4469
                     /gene="ssb"
                     /locus_tag="TV193_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1513822.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGVLIGITGRIQTRNYENQQGQRVYVTEVVADNFKM
                     LEYRQQQQQEDSFDNNNPMDIQADDLPF"
     gene            4483..5310
                     /locus_tag="TV193_001648"
     CDS             4483..5310
                     /locus_tag="TV193_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEL1513823.1"
                     /translation="MGMKEYALAYQKKGFSVLPISPTGKKPMIAFADKPPMTAQEIED
                     FWTQYPDSNIAVRTDKFFVIDIDLHGKANGFESLANWEHLDLITPTLQAKTASGGKHI
                     FYFKHPDVSMTQMIGFLPGVDVKAHLNNYVLVAPSKTPKGVYAWDKDKSKEDGTMVTA
                     SRKLVMAIKQEYNKKNPGSDLDNIYYQISKGAGKRNRTTELFEMIVLGFGDQGGRNDT
                     LARFVGGLLSRSVDPECILRLAETANNNSVEPLGKREMRRTIESMIKKHMRGGGHNR"
     gene            5294..6694
                     /locus_tag="TV193_001649"
     CDS             5294..6694
                     /locus_tag="TV193_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1513824.1"
                     /translation="MATIGEIVNISIKQFSRRKKKILSEEGEQIEVESIVADSPRNVL
                     LAMKSDNKLNDFLRHNEFTGEHEIVEDVKLDAIQLRRGQLPSTFESYLSVYLENHFKT
                     VFKAGALRDGIEAFFAEKTYNPVQEYMEHVYESWDHRERLAQVFQTWLGAEDSIFVQR
                     IAVMFFVGAVSKVFNPWVKFDYTLDLVGGQGAGKTTFLQKVAVEWYTDSAKDFMDKDN
                     YEIMLKSLIVNDDEMVASRKTTFDELKAFVTKTELSFRRSYGRRAEKFPKNFVIARTS
                     NKVEYLGDKTGERRFLPVLVDADQQLVKPFDMTDRDVLQLWGEAVAIYKKGFTLTFDD
                     DFEDELAVYKERFTYKDEAESQIYDYLDMLVPDEWEEMSVVQQHQYTWAYFNNGSYRN
                     ESGFVYEGVKLQASVSAKQILKNVFDIDSARGERIARKIKLIMDNHQDWEYRIKKIKG
                     RTVRAYFKKNMQNEVM"
BASE COUNT         2273 a         1169 c         1679 g         1756 t
ORIGIN      
        1 agtaggaggt gagaatttgg ataatttaca aagacgttta gaacattttg taatcagagt
       61 atcgagacat tgcaacctca cgtttttatt ttaattatat cagaaaggag aataaatgag
      121 ccaacaacat cgaaaatggt cagctcttgt tgaacagcga ctaaaagaaa aagattggac
      181 caaaggcgac ttagcactag cggttggttt gcggagttcg ggaacaatca ctgacttact
      241 cgcgaagggt aaaggtagtg ttgatctaaa ggttagagtt tcaaaaatcc ttggaattcg
      301 tgaaccatgg gaattatttg aaaggtaaca aaaaagtccg acgggaatcg gactcaaaac
      361 aaaaatttac tacttagatt atatcacaaa ggagctaact atggacaata tcttaatgag
      421 tttgtccgac tggataaaag aaattattga aaaaacagtt aacagattag tccaaatcaa
      481 attagatgag gcaaatgccg aattattgac tagagaaaaa gtagcggaca ggcttaacat
      541 gagcccggct acttttgata agtactacag gtatgataaa aattttccaa gcgaattgcc
      601 aggcgttcgt tggaaaaaag ctgaaattat cgcctggcta aataacaaat aagacttttg
      661 gacgaggtct aatcacaagg gaagaaacac tggaaaacaa ttaggagtgt aattatgttt
      721 aataaaaaga aaaaattgca gaagtcattc aataatatta acaagcacat tgatagtctg
      781 acgctgtcag aacaagaaaa gcgtaatcta aaaggattgc tccgtaatgt caaaattaga
      841 acaagggtgg cgtgatgaat gcaattggta tgtatagcat tttagagcgg ctagaccggc
      901 ttgaaaaaat cgtatttgaa acagtagatg acacaggcgg aacgcattag ggaattttat
      961 aaggaaaatc ccactgccag ctatgatgag gtggcagaag ctatcggaac gactaatagc
     1021 aacgtcagag ctaatatagc caaggacatc aaggcaggca gatgtgtccg cctcgaagat
     1081 aaatcattgg actactcagc tcattttggg gcaacggaag ccctagctga tttagtagat
     1141 tggaaaaatg acactagacg ggaatgggtg gaaatgctga ctagagcagc agagaaagaa
     1201 acagatagca ataccatgcg attgcttatc aaggaagcta ataaactgat gaaagaggta
     1261 acgaaataat ggctaaatta tacgaactcg ttggggaata tcgggattta tacgagttaa
     1321 atcttgatga tgaaacctta aaagatacgc tagacagtat tgactgggca gacagattgt
     1381 cagaaaaagt tgaaggctat gcccaggtta tcgaaacagc acttgctgaa gcgaagatgt
     1441 ttgaagaggc tgaaaagaaa ttcaaagcca aaaaagaggc tgctaagaaa aaagccgcct
     1501 ggttgcaagg gaatgtcttc gatgccatga aattgaccaa ccaaacagaa attaagtcag
     1561 gaatttttac agtgcgaatt aagcagaatc ctgaatcggt aaaagttgat gaagagttac
     1621 tgccgaaaaa atacttcaac aaaaagatta cagtcgctcc ggacaagaca acgttaaaag
     1681 aactgctcaa atctggaaag aaaatcaagg gagcagaact aatacgtaca gaaaagttgg
     1741 tgattaaatg atgatactag caattgatcc aagtagtaat cgaattgaaa ctagtacaac
     1801 aggaatcgtc ttactagaca atgcaaggct agttgattat tgggtagttc catttggtgc
     1861 tgagaacttt aaaaagtggt tcaaagatat tggcagaact cttgagtttg ataccgtagt
     1921 ggttgaaaaa ttcgaagtta gagacaacga ttattccaga gataattcag tagtcgagac
     1981 tatatcagca atcgaattat gttatccgga tttagttctg cagagaaatg caggctatca
     2041 gacggatatt ccaaacggtt tgcttaaggc tcttggtttg tggtcttttg ataaaagcca
     2101 tcacaacgat gtgagggcag ctgcaaggtt gggattgttt tgggctcagc gcaacgacat
     2161 tgaggaggtg attgtggaca ttggcaatcg aattacgcaa atggcaagcg gaagcagtta
     2221 agcgtagcga ccgcgattgt cctggtatct ttttggaagc atacgggggt aggggtaaaa
     2281 ctatttgtgc ttttgaaatt gcaaagcata aagaagctaa gaaagtactt gttatcaata
     2341 accgattagc tatcctgaat ggttggaaca acacccatca agatttaggc tatgtaaatg
     2401 attttgagtt agaaatcatg acggatcgca gattgcagaa cagattagca agtggtgaat
     2461 ctatcgagtg tgatgtattt gtcatcgatg aatggcagaa tatgtcgagc gatgccaatg
     2521 tgaaagcata caagaaggtc aaacgcggct atacagtagg gctttctgca acgcctatca
     2581 ggaagaaagg gcagaatttc tacccgttag aaaaaacaat atttggaatg gctgagccta
     2641 atcaacgtga gaactggcaa ttagcccatg gtaagatgaa gtattccaag ttcagctatt
     2701 ctaaacaaga atgggatgac ttccgaaact atgaaagcta cgtggccaat ttaccaaatt
     2761 tcttccgttg ggaagatgtt gaggccattg aagaggcaga agaaaataac ggttttgagg
     2821 taatttttga accagtttgg tgcccacctg ctaatccgaa agagctggaa cagtttagaa
     2881 gtctaaacat cgttggtaaa gatggcaagt ttgcgatggc taagcaaact tttggtcgaa
     2941 agatttttga gaggtactta atccagacag ggtttgaaat tgactttccg aaattgaagg
     3001 cgatcaatgc agatacacct atgctaatac agcttgattt attgttggcc agtcatacag
     3061 aaatgctgat agtcagcaag tcgaagcaaa ttgtagaagt cattcgtgag cgtcaccctg
     3121 agattgggat ttggacggga gacaagaagg acgctctgga gcaaaccaat gtagtagcta
     3181 ccactcaagt acttggtgtc ggtgtggatg gcttgcagta taaatttaaa acgattgttg
     3241 tcctagatcc agtcaatcca tctgatggtg actacgacga ctaccgccag ctattatggc
     3301 gggtaacggg cagccgtcaa caacatgacg tgcgtgtcat tgaattttat ttttgaggag
     3361 acaaaatggc agaacataag gaatcgggta tctttattgt tttgcgttgc attcaggctg
     3421 acctaattgc tccaaaaggg cagtataact cttttggtaa gtatgcctat cgtagcgctg
     3481 aagatatcct ggaggctctc aagcctcttt tgaagaaata tgatgcctca atcgtactga
     3541 gcgacgaaat cgtccaggtt ggggagaggt actatgtaga ggctacagct accctttacg
     3601 caatgggtga atgtgtagga aacaaggctt acgctcgaga agacgagacc aaaaaaggta
     3661 tggacggggc acagattaca ggtgcagctt ctagctatgc tcgtaaatac gctttgaatg
     3721 ggcttttggc tattgatgac aataatgacg ctgatacaga tgcctatcat aatcagaata
     3781 atcaaagtgc tggtaaaact caaaagacta atcaaaaaca agcgagtcag caagagtcaa
     3841 cagcgaaagc tcctgctaaa aataatggtt ctaaaactat tactggagcg caagccaagg
     3901 ctatccgaac agaactcaaa aacatggcag aagctacagg aagtccagct gctgcaattg
     3961 gtaactggtt tatcggaaag atgggcgttg acaagccaga gaacattcct gcagagcgtt
     4021 tgaaagaggc acaacagatt atcgcagatg cgaaaaaagt gaaagggatt gaataaatga
     4081 ttaataatgt agtactagtt ggtcgtatga ccaaggacgc agagcttcga tacactccaa
     4141 gtcaggtggc agttgctacg tttacacttg ctgttaatcg cgcctttaag agccaaaatg
     4201 gtgagcgcga agcggatttc attaactgtg tgatctggcg tcagcaagct gaaaatttag
     4261 ctaactgggc gaaaaagggt gtcttgattg ggattacagg acgtattcag acccgtaact
     4321 acgaaaacca acaggggcag cgtgtgtatg taaccgaggt tgttgcagat aatttcaaaa
     4381 tgctggaata ccgccagcaa cagcagcaag aggattcatt cgataataac aatccaatgg
     4441 atattcaggc tgacgacttg ccattctaat aggaggtact gaatgggaat gaaggaatat
     4501 gctttggctt atcaaaaaaa aggattttct gtattgccca ttagtccaac tgggaagaag
     4561 ccgatgattg cttttgcgga taagccgcct atgactgccc aggaaattga agatttctgg
     4621 actcagtacc cagatagcaa tatcgctgtc cggacggata agtttttcgt cattgatatt
     4681 gacttacatg ggaaagctaa tggatttgag agtttggcca attgggaaca cttggatctt
     4741 atcactccaa ctctacaggc caaaacggcc agcggtggca aacatatctt ttatttcaaa
     4801 catccagatg tgtctatgac gcaaatgatt ggcttccttc cgggcgtcga cgtcaaagct
     4861 catcttaata actatgttct ggtggcaccg tctaaaactc ccaaaggtgt ttatgcctgg
     4921 gataaagaca agtcaaaaga ggatggcacc atggtcacag ctagtcgaaa gttagtcatg
     4981 gccatcaaac aagagtacaa caagaaaaat ccaggtagtg acctggataa tatctactat
     5041 caaattagca aaggtgctgg taagcggaac cggactacgg aactgtttga aatgattgtt
     5101 ttgggatttg gagaccaggg cgggcggaat gatactcttg caagatttgt cggtgggtta
     5161 ctgagtcggt cggtggatcc agaatgtatc ctgcggcttg cggaaacggc caataataat
     5221 tctgttgaac ccttgggcaa aagagaaatg agacggacaa tcgaatcgat gatcaaaaaa
     5281 cacatgaggg ggggtggcca caataggtga aattgttaat atttcaatca agcagttttc
     5341 acgacgaaaa aagaaaatcc tgagcgaaga aggtgaacag attgaagtag aatccattgt
     5401 ggcagacagc cctagaaatg tcttactggc gatgaaaagc gataacaagt tgaatgattt
     5461 tctccggcac aatgaattca ccggtgaaca tgagattgtg gaggatgtaa aactggacgc
     5521 cattcagctt cgacgtgggc agcttccatc tacttttgag tcatatctga gcgtctattt
     5581 ggaaaatcat ttcaaaacag tttttaaggc tggagcttta agagatggca ttgaagcttt
     5641 ttttgcagaa aaaacctaca atcctgttca ggaatacatg gagcacgttt atgaatcttg
     5701 ggatcacagg gagcggttag ctcaagtttt ccaaacgtgg ctaggtgctg aagacagtat
     5761 ctttgttcag cgtattgcgg tcatgttctt tgtcggtgca gtttcaaagg tgtttaaccc
     5821 ctgggtcaaa tttgactata cattggactt agtcggtggc caaggagcag gtaagaccac
     5881 cttcctgcag aaagttgcag tcgaatggta cactgattcg gcaaaagatt ttatggataa
     5941 ggataattat gaaatcatgc tgaagtctct gatcgtcaac gatgatgaga tggtggccag
     6001 cagaaagacc acttttgatg agctcaaggc atttgtaacc aaaactgaac tgtcgtttcg
     6061 taggtcttac ggtcgcagag ctgaaaaatt ccctaaaaac tttgtgattg ctaggacatc
     6121 gaacaaggtt gagtacctag gagacaaaac tggtgagcga cgctttctgc cagtgctggt
     6181 ggatgcagac cagcagttgg tcaaaccgtt tgatatgact gatcgggatg tgctccaact
     6241 ttggggtgag gcggtcgcta tttacaaaaa agggtttacg cttacttttg atgatgactt
     6301 cgaagacgaa ctggcggtct ataaggagcg gttcacttat aaagatgaag cggaatcaca
     6361 gatttacgat tatctggaca tgttagttcc tgatgagtgg gaagaaatgt cagtggttca
     6421 gcaacatcaa tatacctggg catactttaa taatggcagt tatcgtaatg agtcgggatt
     6481 tgtctatgaa ggtgttaaac tgcaagcgag tgtttccgcc aagcagattt tgaaaaacgt
     6541 atttgatatc gacagtgcaa gaggtgagag aattgctcgc aaaatcaagt tgattatgga
     6601 caatcatcaa gattgggaat accgaataaa gaagataaaa gggagaactg tcagggcata
     6661 ttttaagaaa aatatgcaaa atgaagtgat gtaacctttt aggctaaaaa aggctaaaaa
     6721 agcttaaaaa tggcgtttgg gttacatcag gttacatcat tgatgtaacc tgccgaaaat
     6781 ccattaataa caagggttta gggctatttt ttgagaaaaa ttcaaaaaaa gtgatgtaac
     6841 ctatctaaag ccttgatatg actggtttta tgaggtg
//
LOCUS       DARYXS010000093         6802 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.094, whole genome shotgun sequence.
ACCESSION   DARYXS010000093 DARYXS010000000
VERSION     DARYXS010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6802
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.094"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..692)
                     /locus_tag="TV193_001650"
     CDS             complement(<1..692)
                     /locus_tag="TV193_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HEL1513825.1"
                     /translation="MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQG
                     GLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWL
                     IIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLF
                     GLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENH
                     RGIFILGSIFLAT"
     gene            complement(819..2435)
                     /locus_tag="TV193_001651"
     CDS             complement(819..2435)
                     /locus_tag="TV193_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1513826.1"
                     /translation="MKFTAFNLSEDIQSAVVTAGFEKASPIQELTIPLALEGRDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTADNTIQALVIAPTRELAVQSQEELFRFGRDKGVKVRS
                     VYGGSSIEKQIKALKSGAHVVVGTPGRLLDLIKRKALRLDHVETLILDEADECLNMGF
                     LEDIEAIISRVPDDRQTLLFSATMPAPIKEIGVKFMKDPEHVQVKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVQQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQLDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLTMIEHLTKKRMKPLKPATAEEAFQAKKKVALKKIERDFADD
                     AIRSNFEKFKGDAMKLAAEFTPEELALYILSLTVQDPDTLPEVEIAREKPLPFKYVGG
                     GHGNKNGKTGRGNRSRSGRDNRRGGYRHEKRNVYDGDRRPRRDKRDSHDSSGSYDFKR
                     KQKRSNKDLHKKGKAVEAKTSGFIIRHKGN"
     gene            complement(2851..4395)
                     /locus_tag="TV193_001652"
     CDS             complement(2851..4395)
                     /locus_tag="TV193_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEL1513827.1"
                     /translation="MSITEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGQFAKSDWMDIEKQRGISVTSSVMQFDYAGKRINILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGEQRFADLEEGARIFASNPFYEQVLED
                     IELLEEAGNDFSEQAILDGQLTPVFFGSALTNFGVQTFLDTFLAFAPEPHGHKTTTDQ
                     MIDPLNQDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFQKGMAVKLSRTGKSVKLSNV
                     TQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLSVSKNLFEFEPLPTFTPEIFMKVA
                     PKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VIMTPMGKKTVRWISEEDLDQRMSSSRNILARDRFDQPVFLFENDFALRWFADKYPDV
                     KLEAKM"
     gene            complement(4564..5259)
                     /locus_tag="TV193_001653"
     CDS             complement(4564..5259)
                     /locus_tag="TV193_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEL1513828.1"
                     /translation="MNFFAIEPIGLPHVSLLFYLLSVMIAPFLVFMTLQLYQLKSYRY
                     IFLGLQLVQLVGLYSWYALRGFPLTEALPLYHCRMAMLAIFFLPDRSSLKQLFMVLGI
                     GGTFLALLSPDLYPYQLWHVANISFYLGHYALLVNGLVYLLRFYNPSQLKPVLVCRYL
                     ATINFVLVLINLATKGNYGFVMDIPIIHTHHLLMNFVIVTMGLTGLIKLIELIYVRFS
                     EANQLELKLSKER"
     gene            complement(5343..6728)
                     /locus_tag="TV193_001654"
     CDS             complement(5343..6728)
                     /locus_tag="TV193_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEL1513829.1"
                     /translation="MKLTLHEVARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLP
                     LQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQKLAQYYIDKLRVDV
                     IAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIQLLSRIARPHIALLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAP
                     GDPILDPYLPDSQMVIRFGDHQELVVEDIKECKDSLTFRTNVLPRPVTLPLTGKYNAT
                     NAMIAAYVGKLLAVPDEDIIEALETVKLTRHRTEWVKAANGADLLADVYNANPTAMRL
                     ILETFAAIPANPNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQA
                     LAKLASQDYPSGRVSFFKKNNREDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVD
                     RLTAPHAGKSS"
BASE COUNT         2026 a         1625 c         1262 g         1889 t
ORIGIN      
        1 gtcgctaaaa aaatagagcc taaaatgaaa ataccccgat gattttccgg actaaccaat
       61 aagtgcagcg cataataggg attgatagcc tttaggattt ccaaatgctg taagctattc
      121 aagagaccac tgatccccaa aacgctaaac caaaccagca tgactggccc aaataattta
      181 ccaataacac ccgttccaaa gcgctgcagg ccaaacaaga ccatcaatat cagcaaggtc
      241 gttaggatca cattggtctg attctggtaa atactgctga gctcaggaac agcctttaag
      301 ccttcaatgg ctgatgtgac cgtaacagct ggtgtcaagg caccatctga taagagcgtt
      361 gctcccccaa gcatagctgg aatgattaac caccttgaca tccttctaac taaggtaaag
      421 agtgaaaaaa tccctccctc atgatgatta tcagccttta aagcaatcaa aacatacttg
      481 attgtcgtta ccaaggttag agtccaaata atcaaggata ctgagcctaa aataaaagct
      541 tcagacacct gtgaaaggcc gccttgattg tcaaccaacg actgcatggt atacagtgga
      601 cttgtgccaa tatcaccata gacaattcct agtgcaataa taaaacctgc ctttgttgct
      661 ttatcaaagg catcatgatg ggcattagac atcccaatgt tcctcctaag acttaatcat
      721 gccaaatgga ctgagaccat tatagcaaaa tctataacaa aatcaatatt ttcagaaaat
      781 taaaaagaga gctgacaatc atcagctctc ttgaaacttt agttcccttt atgacggata
      841 ataaatccag acgtcttagc ttcgacagcc ttgcccttct tgtgcaggtc cttgttagag
      901 cgtttttgct ttcgcttaaa gtcatagcta ccactgctat catgactgtc acgtttatca
      961 cgccttggac ggcggtcacc atcataaaca tttcttttct catgacgata gccacctcga
     1021 cggttatcac gaccgctacg actacgattg ccacgacctg tcttgccatt tttattgcca
     1081 tgaccaccac caacatactt aaacggtaat ggcttttcac gcgctatctc aacctctggt
     1141 aaggtatctg gatcttggac ggtcaagcta aggatataga gcgctagctc ctctggggta
     1201 aactctgctg ccaatttcat cgcatcgccc ttaaatttct caaagtttga gcgaatagca
     1261 tcatctgcaa aatcacgctc aatttttttg agggcaacct ttttcttagc ctgaaaggct
     1321 tcctctgccg tagctggctt gagtggcttc atgcgcttct tagtcaggtg ctcaatcatg
     1381 gtcagatagc ccatctcatt tggtgagaca aaggtaatgg attcccctga cttacctgca
     1441 cgaccggtcc ggccaatacg gtgcacatag ctttctggat cctgtgtaat atcgtaattg
     1501 tacacatgag taacgcctga aatatcaagc ccacgcgcag caacatcggt tgccactaaa
     1561 atatcaagtt gatcattttt aaagtcgcgt atgacacgaa ggcgcttatt ttggtcaagg
     1621 tcaccatgta tcccttctgc gcgaaaacca cgcaatttta agccgcgcgt gatttcatca
     1681 acacgacgct ttgtgcgacc aaatacaatt gatagctctg gctgctgaac gtccatcaga
     1741 cgtgtcatgg tatcaaattt ttcttgctcc ttaacacgca catagtattg atcaacattc
     1801 acatttgtta attccttgtt tttaacctga acatgctcag gatccttcat aaacttgaca
     1861 ccaatttcct tgattggagc tggcattgtt gctgaaaata acagggtttg acgatcgtca
     1921 gggacacgac taataatcgc ttcaatgtcc tctaaaaatc ccatattcaa gcattcatca
     1981 gcttcatcta aaatgagtgt ctcaacatgg tctagcctca aggccttacg cttaatcaaa
     2041 tctaacagac gtcctggcgt tccaacaacg acatgcgccc cagactttag ggccttaatt
     2101 tgcttctcaa tgcttgagcc accatatact gagcgaacct tgacgccttt atcacgacca
     2161 aaacggaaca gctcttcctg actttggaca gccagctcac gcgtcggagc aatcaccaat
     2221 gcctgaatgg tgttatcggc tgtacgaatc ttattcagag ttggtagacc aaaggctgct
     2281 gtttttcctg ttcctgtctg agcctgtccg ataacatctc gtccctccaa ggctaacgga
     2341 atggtcagct cctgaatagg agaggctttt tcaaagcctg ctgtaacaac agctgactga
     2401 atatcttctg ataagttaaa tgctgtaaat ttcaattgtt tctcttttct aaaaaggcag
     2461 tgcgaagctg ccttataaac cttttaatat tgtcgttcga ttaacaacct atttagtgta
     2521 acataattaa tattaaaaag ataggaaata agccatgaaa gtgtttttat ctcaaaatga
     2581 ttaacactat caggcagcta aattgataaa agcgtcactc cttattgctg attggctaac
     2641 agcctcaaaa aggcctcgtc ggacttgctt acctatgctt tttatctact ctgctaaaaa
     2701 gactcggcac agagacgagc cttcgcgatt ccatcaccaa tcttcaaaga cagcaattag
     2761 gattcctgaa agctccttat gccaatagcc tgccttttct tagcagcaga agtgcaaaaa
     2821 cggactaggt tcccctaatc cgcttagctg ctacattttt gcttctagct taacatctgg
     2881 gtatttatct gcaaaccaac gaagcgcaaa gtcattttca aagagaaaaa caggctgatc
     2941 aaagcgatcc cttgccaaaa tgtttcggct tgaggacatg cgttggtcca aatcctcctc
     3001 tgagatccaa cgaacagtct ttttgcccat tggtgtcatg atgacctctg cattgtactc
     3061 accctccata cggtgcttga aaacctcaaa ctgcagctga ccaactgcgc ccagcatgta
     3121 ttcacctgtc tgataattct tataaagctg aacagccccc tcctgtacaa gctgctcaat
     3181 acctttgtgg aaagattttt gcttcatgac attcttaggt gcaaccttca taaaaatctc
     3241 tggggtaaag gtcggcaatg gctcaaattc aaacaggttt ttactaacgc tcaaggtatc
     3301 tccaacctga taagtccctg tatcgtagac cccaataata tcaccggcaa ctgcattttg
     3361 gacattttca cgagactcag ccataaactg agtaacattt gatagcttaa cgcttttacc
     3421 tgtacgagac agctttacag ccattccctt ttgaaactct ccagagacaa tacgcacaaa
     3481 ggcaatgcgg tcacgatgct tagggtccat gttagcctga atcttaaaga caaagcctga
     3541 aaaatcctga ttgaggggat caatcatctg gtccgttgtc gtcttatgcc catgaggctc
     3601 tggtgcaaag gctaaaaagg tatctaaaaa ggtttgtacc ccaaaatttg ttaaggcaga
     3661 gccaaagaat accggagtca gctgaccatc taaaatagcc tgctctgaaa agtcattacc
     3721 tgcctcctcc aagagctcaa tatcttcaag cacctgctca taaaaagggt tgctggcaaa
     3781 aatccttgcc ccctcctcta aatcagcaaa cctctgctcc cccttataaa gctccaagcg
     3841 tttgttgtgc aaatcataca gaccttcaaa ggctcgtccc ataccaattg gccagttcat
     3901 ggggtaagaa gcaatcccaa gaacctcttc tagctcctcc aacaactcca aaggctcacg
     3961 tccatcacga tctaatttat taataaacgt aaaaacaggt atgttacgat gcttaacaac
     4021 ctcaaagagc tttttcgtct gtgcttcgat ccctttagcc gaatcaacaa ccatcacagc
     4081 agcatcaact gccattaagg tacgataagt atcctctgaa aagtcctcgt gaccaggtgt
     4141 atctaaaata ttgatacgct taccagcata atcaaactgc atgactgatg atgtgactga
     4201 aatcccacgt tgcttttcaa tatccatcca atctgactta gcaaattgac cagatttttt
     4261 tcctttaacg gtcccagcct cacgaatctc accaccaaaa taaagtaact gttctgtaat
     4321 agttgtttta ccagcatctg ggtgactgat aatcgcaaag gttcgacgct ttttaatttc
     4381 ttctgtaatt gacattcttt tttccttatt tgttcacatt gcagagcaag actctgatta
     4441 atagcttcaa gtcacacgtc acagttatgt ctacatgatc tcactcctaa atactgatat
     4501 gataaaaaga gctgctagag cagctccttt attatagctg attcgaagcg ctttttcaac
     4561 gccctatctt tctttagaga gcttcagctc taactgattg gcctcactaa atctcacata
     4621 gataagttca atcagcttaa ttaaaccagt caaccccatt gtcacaatga caaaattcat
     4681 aagcaggtga tgcgtatgaa taatcggaat atccatcaca aagccgtaat ttccctttgt
     4741 tgccaaattg atcaatacta aaacaaaatt aatggttgcc aagtaacggc aaacaaggac
     4801 tggctttagc tgacttggat tgtaaaaccg cagcaggtaa accaagccat tgaccaaaag
     4861 agcataatgc cccaggtaaa aagaaatatt agccacatgc catagctgat aagggtataa
     4921 atcaggtgat aacagggcca aaaaggtccc accaatccct aaaaccataa aaagctgctt
     4981 taagctactg cgatccggta agaaaaagat agctagcatg gccattcggc aatggtaaag
     5041 cggcaaagcc tctgtcaacg gaaagcctcg caaggcatac cagctataca aaccaaccaa
     5101 ttggaccaac tgaagcccta agaagatata gcgatacgac tttagctgat agagctgcag
     5161 ggtcataaaa accaaaaacg gcgctatcat caccgacaat agataaaata gcaaggacac
     5221 atgcggtagc ccaataggtt caattgcaaa aaaattcata aacatccctt tctacatttt
     5281 ttcattatac cttaatctta atgagaggac aagatgtttc atgtgttttt tctgaaaaag
     5341 tgttaggagg acttcccagc atgaggagct gtcaggcgat caaccacatt tgctagcagc
     5401 atggagtggc tgccctttag cagcatctgg tcattaggct caagaatagt caacaggtac
     5461 tggcacatgt cctcgtattg atcctctcga ttattctttt taaagaagct aactctgcca
     5521 cttggataat cttgactagc tagcttggcc aaggcttgaa tatcatcacc gtaaaagacc
     5581 aattgatcaa tacgcttggg atctaagctg gtaatcagct gagaatgcaa agcaactgag
     5641 tcagcaccta attccttcat atcagctaaa acagctattt ttttgccatt agggttggcc
     5701 ggaatggcag caaaggtttc caaaattaac cgcatagcag ttggattggc attgtacaca
     5761 tctgccaaaa ggtcggcgcc attagccgcc ttgacccact cggttcggtg gcgtgtcagc
     5821 ttgacggttt ctaaagcttc tataatatcc tcatcaggca cagccaagag tttaccaaca
     5881 taagctgcta tcatagcatt ggttgcattg tattttccag ttaagggaag agtgaccggt
     5941 cttggtaaga cattagtcct aaaggtcaag gagtccttgc actctttgat atcctcaacc
     6001 accagctctt gatgatcgcc aaagcgaatg accatctgac tatccggcaa atatggatca
     6061 aggataggat caccaggagc aattaaaatc ccgttagagt ccatcccatc aacgatttgc
     6121 attttccctt cggcaatctt ctcgcgagag ccaaagtagg ctaagtgagc ctcaccaata
     6181 agggttagca atgcaatatg aggtctggca attctagaga gcagctgaat gtctcccata
     6241 tgatcctgcc ccatctctaa aacaatcttc tcagtatcct ctggcatgtg aagcaccgta
     6301 taaggcaagc caatgtcatt attataattg ccctgggttt tgtaggtctt ataagctttt
     6361 gccaggaccg cttcaatcat atccttggtt gatgttttac cgtttgagcc tgttacagca
     6421 atgacatcga cacgtagctt atcaatataa tactgggcta atttttgaaa ggcagccaag
     6481 caattctcaa ctagtatata gggtctgcca ctgattgctc tttctgaaaa ggtagctacg
     6541 gccccatttt caaaggctaa gtcaataaaa tcatggccat ctcgctcacc ctgtagcggt
     6601 aaaaaaagat caccttttgt gatgtttcta ctgtcaaatt caatctgatt cagaggaacg
     6661 tcgtctaaat cagaaagact attttgagca tcaacaactc ttgccacttc atgtaatgtt
     6721 aatttcatct tatttttcct cttaaaacac tggtttttaa agctttgctt atattatagc
     6781 ataacatatt aggaatattc tt
//
LOCUS       DARYXS010000094         6740 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.095, whole genome shotgun sequence.
ACCESSION   DARYXS010000094 DARYXS010000000
VERSION     DARYXS010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6740
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.095"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            85..366
                     /locus_tag="TV193_001655"
     CDS             85..366
                     /locus_tag="TV193_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEL1513830.1"
                     /translation="MPTPLEQRQLKQQKQEQVSQQKFQEFQDLNGHSSKLKELIFFAR
                     IAVFSLITVLFAFVLLVMNLAPVWAFLIASAISLAITSFLSKAITLLMS"
     gene            complement(492..917)
                     /locus_tag="TV193_001656"
     CDS             complement(492..917)
                     /locus_tag="TV193_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEL1513831.1"
                     /translation="MSNFFKTLVIGVASGAATAYFLSTEKGKVLKARAQRAYEAYRQN
                     PEEYHQMAKEKGSEYSQLARHTFNDLKTRFESGDMTTDQVFDFIKEKTSQFVHQAKEA
                     ASEHDKADDVIIDLDEEDIIINYPEDDSEKEAASNKSEE"
     gene            complement(914..1318)
                     /locus_tag="TV193_001657"
     CDS             complement(914..1318)
                     /locus_tag="TV193_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEL1513832.1"
                     /translation="MNLVGISLLIIALAFVALVIFLIVVLKKVSEAVDEAKKTITVLT
                     SDVNVTLYQTNEILAKANVLVDDVNGKMTTIDPLFVAIADLSESVSDLNVQARHLGRR
                     ATNATSNAAKVGKVALVGKVASKLFGKKEKRS"
     gene            complement(1340..2119)
                     /locus_tag="TV193_001658"
     CDS             complement(1340..2119)
                     /locus_tag="TV193_001658"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEL1513833.1"
                     /translation="MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSD
                     DIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLF
                     VYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMF
                     IDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMR
                     TDSLMLLGIRVSQYMSVLLIIIAIVFIFKRHRQKGISYYQE"
     gene            complement(2116..3048)
                     /locus_tag="TV193_001659"
     CDS             complement(2116..3048)
                     /locus_tag="TV193_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEL1513834.1"
                     /translation="MTVTVKMLVTKVKLDVVYATDDLLEKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVIVSRGLAIPEEMVQAA
                     QEEGIALFSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVFAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVSIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEERLTRLISKNEEGK"
     gene            complement(3326..3598)
                     /locus_tag="TV193_001660"
     CDS             complement(3326..3598)
                     /locus_tag="TV193_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEL1513835.1"
                     /translation="MESKFYKQRKHKLVAGVISGLADKYGWDLPLARVLAALLIYFTR
                     FGVVIYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNDEDEGWFW"
     gene            complement(3662..4099)
                     /locus_tag="TV193_001661"
     CDS             complement(3662..4099)
                     /locus_tag="TV193_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEL1513836.1"
                     /translation="MSLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLD
                     FNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPKLQ
                     SHQANYLYICQDCGQAYDRKRPINLAVFACGRCHGRLIEKNQS"
     gene            complement(4086..6218)
                     /locus_tag="TV193_001662"
     CDS             complement(4086..6218)
                     /locus_tag="TV193_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEL1513837.1"
                     /translation="MENMNHQNISEALGVTPKQISQVLTLTAEGNTIPFIARYRKEAT
                     GNLDEVVIKAIIDMDKSLTQLRERKDTILAKIEGQGKLTAALKEAIEAADKLADLEEL
                     YLPYKEKRRTKATIAREAGLSGLARLILQNAQDLETKAEAFITEGFSDPQAALAGAVD
                     ILVEAMSEDSRLRSWTYNEIWKYSRITSSLKEASLDDKQVFQIYYAFSETVSNMQGYR
                     TLALNRGEKLGVLKVSFEHHIDKMLRFFSLRFKEHNAYIDDVINQTIKKKIVPAMERR
                     IRTELTEMAEDGAIKLFSENLRHLLLISPLKGKMVLGFDPAFRTGAKLAVIDPTGKLL
                     TTQVIYPVAPANQAKIQAARVALAQLITDYQIDIIAIGNGTASRESEAFVAEVLKDFP
                     ETSYVIVNESGASVYSASELARHEFPELTVEKRSAISIARRLQDPLAELVKIDPKAIG
                     VGQYQHDVSQKKLSEHLDFVVDTVVNQVGVNINTASPALLAHVSGLNKTISENIVRYR
                     EENGEITSRAEIKKVPRLGAKAFEQAAGFLRIPNAKNILDNTGVHPEAYPAVKKLFQL
                     LAIKDLDEPARAKLQAVNLEEMAEQLTLGQETLKDIIADLLKPGRDLRDDFEAPVLRK
                     DILSVKDLAVGQRLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSEAFVNHPSQVVSVG
                     DLVTVWVSKVDLDRHKVNLSLVPPRESD"
     gene            complement(6386..6712)
                     /locus_tag="TV193_001663"
     CDS             complement(6386..6712)
                     /locus_tag="TV193_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513838.1"
                     /translation="MKKLLLTSAAALALATVAVSTTKVEAFSRGHVIEHTINDTKSLS
                     AARWGSRLQILNLLTRFKHKLGEDGFRSYNRQFRARVGAAKSVSEIDELYNKFEKELE
                     ELEDLT"
BASE COUNT         1939 a         1628 c         1256 g         1917 t
ORIGIN      
        1 aacgagaagc cttcaaaaaa aaagatgaca accatcagct tttatggtaa aatggttggg
       61 tatcttacgg gaaaggagag gactatgcct acaccattgg agcagcggca gctcaagcag
      121 cagaagcaag agcaggtctc gcagcaaaaa tttcaagagt ttcaagacct caatggacac
      181 agtagcaagc tcaaggaact tatttttttt gcccgtattg ctgtttttag tttaatcact
      241 gtcttgtttg catttgtcct tcttgtcatg aatttggcac cggtttgggc ctttctaatt
      301 gctagtgcta tcagcctagc catcacttcc tttctttcaa aggccatcac gttattaatg
      361 tcataaacag ttagagcttg gcttcgctaa gctctttttt cattactctt attgcctatt
      421 ttcttgaata aacgagtagc ccacatcaca aaaggccctc catagctgag agagccctta
      481 tttttgcctt attattcttc agacttattg ctagctgctt ctttttctga atcatcttca
      541 ggatagttga taataatatc ctcttcatcc agatcaataa tcacatcatc agccttgtca
      601 tgctctgaag cagcttcctt tgcctgatga acaaattggc tggtcttttc cttgataaaa
      661 tcaaacacct gatcagtggt catatcccct gattcaaacc tggtttttaa atcattaaag
      721 gtatggcgag ccagctgact gtactcactt cctttttctt tagccatttg atgatattcc
      781 tcaggatttt gacgataggc ttcataggcc ctttgtgcgc gagccttcaa gacctttcct
      841 ttttcagttg acaagaaata agcggtagct gctcctgaag ctacaccaat caccaacgtt
      901 ttaaaaaaat tactcatgac cttttctcct ttttaccaaa taatttagaa gcgaccttgc
      961 cgacaagagc tactttaccc acctttgcag cattgcttgt ggcatttgtc gcccgacgtc
     1021 caaggtgtct ggcctgcaca ttcaaatcag aaacactttc tgacaaatct gcaatagcaa
     1081 caaagagagg atctattgtt gtcatcttac cattcacatc atctaccagc acattagcct
     1141 tagctaatat ttcattggtt tgataaaggg taacattgac atcactcgtt aaaacggtaa
     1201 tggttttttt agcctcatca actgcctctg acaccttttt taacaccaca atcaaaaaaa
     1261 taaccagagc aacaaaggct aatgcgatta tcagcaatga aatgcccact aaattcataa
     1321 acgtctcctc tttctatccc tattcttgat aataagaaat tcccttttgt cgatgccttt
     1381 taaagataaa aacaatcgca atgataatga gcagcaccga catgtattga gaaacacgaa
     1441 ttcctaaaag catcaggctg tccgttcgca tgccctcaat caccaatcga ccacagccat
     1501 accaaatcag gtaaaatgag ataatatccc catctactaa tgacctgggc ttacgccgcc
     1561 acaccatgat aatgacaaag ccaatcaggt tccacatgga ctcatataaa aaggtgggaa
     1621 cacgatagct gccatctata aacatctgct ggcgaataaa actaggcagg taattgagct
     1681 ggctgacagc cctgccatag gcctcttggt taaagaaatt tccccatctg ccgatggcct
     1741 gagcaagcat gacactaggc gctgcaatat ctaagaaatg gataggattc agcaccttat
     1801 agtagcaata aacaaagaga acaatggtac ctgttatcaa gccgccatag atggcaatcc
     1861 caccattcca aatagcaaag atatcactca aatgctgaga ataataggac cattcaaagg
     1921 ctacataata gattcttgct ccaataattg ccaaaggaaa ggcaatcaga ataaaatcaa
     1981 taatatcatc actggtcatt ttttttcgcg gggcttcttt ggctgccaaa taaaccgcta
     2041 aaagtaatcc caccaagata caaaccgcat accagtgaag actaagagga ccaagcttaa
     2101 aggctattgg attgatcatt tgccctcctc atttttgctg attaaacgtg taaggcgctc
     2161 ctcaaaggtt ttggtagcat caaagcccat ctctttcgca cgatggttca tggcagcagc
     2221 ctcaataacc actgacacat ttcgacctgt tttgacagga atgcgaatcc ttggaatact
     2281 gacaccagaa aaggtaatct cttcattgcc attgcccaag cggtcaaaga ccttgccagc
     2341 ctcaaaattc tccaaataaa tagccaactg cacctgtgag gaatccttga cagcactagc
     2401 accgtacagc gacatgacat caataatgcc aacaccacga atctcaagga gatgacgtaa
     2461 aatctctgct ggctcccccc atagcgtctc ctcatcttta gcaaagacat ctactcggtc
     2521 gtctgccacc aagcgatggc cacgcttgac caactctaag cctgtctcac ttttaccaat
     2581 acctgaatca ccttggatca gcacccccat accgtaaata tccatcagca ccccatgcac
     2641 acttgttcgc tctgctaagg aagcatcaag aaaataagac atctcaccag ctaagcggct
     2701 ggtagatacg cggctgctaa acagagcaat accttcctcc tgcgctgcct gaaccatctc
     2761 ctctgggata gctaggcccc tagatacaat cacagctggc gtgtcttttt taaacatttc
     2821 ctttaagact gagtagcgat tgtgtgaggt catctgagtg aggtaggacc attctttcat
     2881 gccaaacagc tgaagccgct ctggggcata gtaatcaaaa tagccggtca tctcaagacc
     2941 cggacgcgaa atatctgagg tcgttatctc cttttctagc aagtcatcag ttgcatagac
     3001 aacgtcaagc ttgacctttg tgactaacat cttaacggta actgtcataa tttctccttt
     3061 tttaatatta tatcataaat cactatctaa gcccttacaa atacttattt ttcaaagaag
     3121 ctttcaaagt gcttgatcat actaaaaaag aatcctgcaa cagctgcctc aggctcactt
     3181 aaagcaggca ctagcctaaa gcggacaaac aacaaaaggc cctatctcat cagataaagg
     3241 cctacagcca gctttatttc tgataatcac gctagaggca ctattaaaat tcctgtcaag
     3301 cttttaatag tcgctcgctg tggtcttacc aaaaccagcc ttcatcttca tcatttagga
     3361 catcagcatc cttgcgacgt cttggtcctc tcccgtaacg ttcttcaagt aggtcctctt
     3421 tatatggtag gaagatggct aaaagaatat aaataacaac cccaaagcga gtaaaataga
     3481 tcaataaggc ggcaagcaca cgagctaggg gcaaatccca gccgtattta tcagctaaac
     3541 cagagataac tccagccact agcttatgct ttcgttgctt ataaaattta gattccatgt
     3601 ctcctcgcct ccttattcta tgatactagt ttattccttt tttagcaaaa taaaatcagc
     3661 cttacgactg atttttttca atgagcctgc catgacacct gccgcaggca aataccgcca
     3721 gattgatagg acgttttcgg tcataagctt ggccgcaatc ttgacagatg tagaggtaat
     3781 tagcttgatg tgactgtaat tttggagcgt atctcagacc gtctacttgg tctagaagct
     3841 ccttaaaggc ttgatcctta tgccgaaagc ccagcccctc aaaatagagg tgataatgac
     3901 aaagctcatg cctaacgatc tgtctaaaga cagtctcccc atgctcctct aagattttgg
     3961 gattgaaatc cagatgacca tcctttggaa aaaaacgtcc gcctgttgtt cttagtcgtc
     4021 tgttccaaga agcctgatgc ttaaagggct ttccaaaatc agctagcgag acctctctaa
     4081 cataatcagt cagactcacg aggcggcact aagcttaggt tgaccttgtg gcggtctaag
     4141 tcaaccttag aaacccaaac agtgactaaa tctccgacag aaacgacctg acttgggtga
     4201 ttgacaaagg cctcactcat ctctgaaatg tgaatcaaac cgtcctcatg tacaccaata
     4261 tcaacaaaag caccgaagtc aaccacattt ctaacagttc cctctagcct ttgaccaaca
     4321 gccagatcct ttacactcaa aatgtccttt cgaagaacag gagcttcaaa gtcatcacgc
     4381 aagtctcttc ctggcttcag caaatcagca atgatatcct tgagcgtttc ttgaccaagc
     4441 gtcaattgct ctgccatttc ctcaagatta accgcctgta atttggccct tgcaggctca
     4501 tctaagtctt taatcgcaag taattgaaag agctttttga cagccggata ggcttctggg
     4561 tgaacgcctg tattgtctaa tatattctta gcattgggaa tacgcaagaa gcctgctgcc
     4621 tgctcaaagg cctttgcgcc tagtctaggg acctttttga tctcagcacg tgaggtgatc
     4681 tctccatttt cttcacgata cctgacgata ttctcagaaa tggttttatt tagccctgaa
     4741 acatgagcca gtagggctgg actagctgta ttgatgttaa ccccaacctg attaacaacg
     4801 gtatcaacga caaaatccag atgctcagat agctttttct gactaacatc atgctggtat
     4861 tgtccgacac cgattgcttt tgggtcaatt ttgaccagct ctgctagcgg gtcttgcaag
     4921 cgacgcgcaa tagagatggc tgagcgcttt tcaaccgtca gctctggaaa ttcatggcgg
     4981 gctagctctg aggccgaata aaccgaagct ccgctttcat taacaatgac ataagaggtt
     5041 tctggaaaat cctttagcac ctctgcaaca aaggcttcac tctcacgact ggctgtgcca
     5101 ttaccaatgg caataatatc aatctgatag tcagtgatga gctgagctag agctactctt
     5161 gctgcttgaa tcttagcttg attagctggt gccaccggat agataacctg agtagttaac
     5221 agctttccag tcggatcaat caccgctaat ttggcccctg tcctaaaggc cgggtcaaag
     5281 cccagcacca tttttccctt tagtggtgaa attagcaaaa gatgacgcaa attttccgaa
     5341 aagagcttga tagcaccgtc ctcagccatt tcagttaatt ctgtgcggat acgtcgttcc
     5401 atagcaggaa caattttttt cttgattgtt tggttaataa catcatcaat ataagcattg
     5461 tgctccttaa agcgaaggct gaaaaagcgc agcattttgt ctatatgatg ctcaaaggat
     5521 acctttaata cgcctagctt ttccccacga ttgagagcta gggtcctgta gccctgcatg
     5581 ttagataccg tctcagaaaa cgcatagtaa atctgaaaga cctgcttgtc atctaagctg
     5641 gcttccttta ggctagaggt tatacggcta tacttccaaa tctcattata ggtccaggac
     5701 cttagcctgc tatcctctga catggcttcg accaaaatat caacagctcc agcaagggct
     5761 gcctgtggat ccgaaaaacc ttctgtgata aaggcctctg ccttagtttc taggtcttgt
     5821 gcattttgaa ggatcagtct agctagtcca gataagccgg cttctcgagc aatggttgcc
     5881 ttggtacgcc gcttttcctt gtaaggcaaa taaagctcct ctaggtcagc caatttatca
     5941 gctgcttcta tagcttcctt aagggcagct gttagtttcc cttgtccttc gattttagca
     6001 agaatggtgt ctttacgctc cctaagctgt gtgagggact tatccatatc aataatggcc
     6061 ttgatcacca cttcatcaag gttacctgta gcttccttac gatagcgcgc aataaaggga
     6121 atggtattac cctcagcggt aagggtaagc acttgactaa tctgttttgg ggtgaccccc
     6181 aacgcttctg aaatgttttg atgattcata ttttccataa cagttcttat tatagcacaa
     6241 agaaagaggg atagaacaag ataaaagctt tatgacaaat aagtgtcaag aaaacaaaac
     6301 ttatcttttc agatacttct aaaggctaag aaaaaacgat ctccaaacgg aaatcgtctt
     6361 ttagctactt agtggttagt caaaattaag tgagatcttc taactcttcc aactcctttt
     6421 caaacttatt ataaagttca tcaatttcac ttactgattt tgctgcacct accctagctc
     6481 tgaattgtct gttataagac ctaaagccat cctctcctag tttatgctta aatcgtgtta
     6541 acagattaag gatttgcagt cttgaccccc agcgcgctgc actaagcgac ttggtgtcgt
     6601 taatcgtatg ctctataaca tgcccacgag aaaacgcctc tacttttgtt gtgctaactg
     6661 ctactgttgc taaggctagc gctgcagcac tagttaatag taattttttc atgatatgac
     6721 tcctatttgt ttttttatgt
//
LOCUS       DARYXS010000095         6630 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.096, whole genome shotgun sequence.
ACCESSION   DARYXS010000095 DARYXS010000000
VERSION     DARYXS010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6630
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.096"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(48..539)
                     /locus_tag="TV193_001664"
     CDS             complement(48..539)
                     /locus_tag="TV193_001664"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513839.1"
                     /translation="MKKLVLASAAALVLAGATVSTGTVSANSSRYNYTGWNQGGYSWK
                     YLRLRNKNPYSRRTLTEDYSDQRKNEAKDSIKELSKLSDKEKKNFADRIDALTDTYAI
                     SSILSEAKNKNNDYLEFDKEYEALFNSNKYKLEIEKIKDRVYFDEGYSARQGINDLKS
                     LEN"
     gene            complement(726..3227)
                     /locus_tag="TV193_001665"
     CDS             complement(726..3227)
                     /locus_tag="TV193_001665"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEL1513840.1"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACA
                     IAKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK"
     gene            complement(3816..4679)
                     /locus_tag="TV193_001666"
                     /pseudo
     CDS             complement(3816..4679)
                     /locus_tag="TV193_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514825.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(4961..6478)
                     /locus_tag="TV193_001667"
     CDS             complement(4961..6478)
                     /locus_tag="TV193_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1513841.1"
                     /translation="MSIENLFTKQQWRELELITLLSETKNPLYYKDACQMLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSGLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLIEVKIDFAIFRQLKLLSAVNLIRYLKGF
                     KIGKHKALSSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLEK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDISE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
BASE COUNT         1873 a         1501 c         1223 g         2033 t
ORIGIN      
        1 agactttcag ttggattatt ttgataaata ataaatctgt ctactgttta attctccaga
       61 cttttcaagt cattaatccc ttgtctagct gagtaacctt catcaaagta cacacgatcc
      121 tttattttct ctatttctaa cttatactta tttgaattga ataaagcctc atattcttta
      181 tcaaattcta aatagtcatt attcttattt ttagcttctg atagaataga gctgattgca
      241 taggtgtcag tcaaagcatc aattctatca gcaaaattct ttttctcttt atcactaagc
      301 ttactcaatt ctttaatact atcttttgct tcattctttc tttgatcaga atagtcttct
      361 gtaagggtac gacgtgaata aggattttta tttcttaggc gcaaatattt ccatgagtac
      421 ccaccttgat tccaaccggt ataattatat cttgaactat tcgcacttac tgttcctgta
      481 cttacagttg ctcctgctaa tacaagtgct gctgcactgg ctaaaactaa ttttttcacg
      541 ttgaaaaatc ctccatttat taaataagtt tagggtttta ttttactatt atcttcaagc
      601 ttcttcaata tcagttttaa tagcgtgtta caaaacaaga ataaccactc atgtaaacga
      661 gtggttatca gctttttata gtattgggct caaaattata aggaaggcat tttttgctag
      721 ggtctttatt tcaccacaat attaacgagc ttattaggaa caacgatgac ctttgccact
      781 tccttgcctg caatttcagc ctgtatttta tcatgtgcta gggctacttt ttctagctct
      841 tctcttgaga ggtcttttgc cacgacaagc ttagccttga cctttccttt aatttgaaca
      901 acgatttcaa catcattttc aacgagctta ctatcgtcat gggttggcca tgcaacatac
      961 gagatggatt gacctgaagc tgtcaggatc tgccataatt cttcacctag gtgtggggca
     1021 aatggggcta gcaattgaac gaagcctttg gcgtatgcca cataaagctc gtcctcttta
     1081 ttggctgcat tgacaaaaat catgagctgg gcaatagcag tattgaattt catgccttcg
     1141 atttgttctg tgactgcctt aacagtctca tggtaagcct tatctaaagc tccgctattt
     1201 tctgcaacaa tttcctttgt cgtgatcaaa cggtaaacac gatctaggaa cttgcgtgct
     1261 ccctcaaggc cttcttcaga ccaagcaatg gacgcatcaa gtggccccat aaacatttca
     1321 tacacacgca gggtatctgc tccgtactgc tccaccacat cgtctgggtt gacaacgttt
     1381 ttcagtgatt tagacatctt agcaggggcc tgctcaagct cctcgcctgt ttccatgtgg
     1441 aagaagctac catcacgctt gtcaacctta tccgttgcga ccaaggcccc acgatggtcg
     1501 cgatagctgg ttcccaaaat catgccttga ttaaagagct tttggaaggg ctccttggtt
     1561 ggcactacac ccagatcata gagtaccttg tgccagaagc gtgcataaag cagatgaagc
     1621 actgcgtgct cagcaccacc aatgtaaata tctactggca gccattgctt taacaggtcc
     1681 ttatcagcta attgctcatc attgtgtggg tcaatatagc gaaggtaata ccagcttgag
     1741 ccagcccact gtggcatggt gttggtctca cgacgccctt tgaccccatc ctcgcgggtc
     1801 acctcaagcc agtcagtcaa gttagctagt ggtgattctc ctgtaccaga tgggcgaata
     1861 tccttggtca ctggcaaaac aagtggtagg tcctgctcag gaaccgctgt cgaggtaccg
     1921 tcctcccaat gaatgattgg gattggctca ccccagtagc gctgacgact gaacagccag
     1981 tcacgtaggc gataagagac cttttcatga ccgacaccag tctcctccag ccacgccacc
     2041 attttagcaa tggcacaagc cttatcaaga ccatctagga agtcagaatt aatgtgaata
     2101 ccgtcctctg tgtaggcagc ctcatcaaca ttgccccctt caagcactgg aataatctca
     2161 agattgaatt gctttgcaaa tgcccagtca cgctcatcat gcgctggcac tgccatgata
     2221 gcacctgtac cgtagcttgc aagcacataa tccgcaatcc agataggcat ttctttgcca
     2281 ttgaccgggt tgatcgcata ggctcctgtc cagacacctg ttttttcctt ggcaagatcg
     2341 gtacgagcaa ggtcagattt gaggctcgct tggcgtttgt actcagcaac agcctgcgct
     2401 tgctctgctg tagtaatgct atctactaag gcgtgttctg gtgccaaaac agcataggtt
     2461 gcaccaaaca gggtatcagg tcgtgtggta aagacggtga agtctttatc ggtatctttg
     2521 accttgaagg ttacattagc ccctgttgat ttaccaatcc agttgcgctg catatccttg
     2581 atcgactctg gccaatccac ttcctccaga tctgctagca agcgctctgc gtaggctgtg
     2641 attttgagca tccattggcg catgggctta cggacaactg gatagcctcc acgctctgat
     2701 gtgccatcag ggagaacctc ctcattcgca atagctgttc ccagctcttc aacccagtta
     2761 acaggcacct cagcttcata ggctaggcct ttttcataca attttgtgaa aatccactgt
     2821 gtccatttgt agtaactagg atcagttgta ttgatctcac gatcccagtc atacgagaag
     2881 ccaagagcat tgatctgacg tttaaagttg gcaatgtttt ctgctgtaaa ctcagcaggg
     2941 tcattaccag tatccatcgc gtattgctca gcaggcagac caaaggcatc ccagcccatt
     3001 gggtggagga cattataacc ctgtgcacgc ttgaagcggc ttaaaatatc agttgcagtg
     3061 taaccctcag gatgcccaac atgaagacct gcaccggaag gataaggaaa catatctaaa
     3121 gcataaaatt taggctttga ggcatctgtc cccgttttaa aggtatgatt atcagcccaa
     3181 aaggcctgcc acttaggctc aatggctttg tgattgtaaa atgtcatgtg aattctccca
     3241 tgtaaaaagt ctagtcttct tattatagca cgatatcaga cttttaggaa tgggcaagca
     3301 atattgctgc cacgacgtcg gcatcacaaa aatgcatgta accattttct agctgcatgc
     3361 atttttttaa tctatgttca gcggttttgc attgcaatat caccagtttc tcgattgcta
     3421 tttgactatt tcataacata ttgccaaaaa aactatactg atgataaaaa ctcgctatga
     3481 gaaagtgtaa ctgtcttcat gcgtttgtca cgacattgct aaagcccttt agactagata
     3541 gcgcgtctct gcgacgcata agctcaagcc ttacgagcca actcataaaa cagccaaata
     3601 tccgctatca tctcacttgg ttttagatct ggtctagctc tagttttaag ctctcaaaga
     3661 ggtattgagc ttgaccaagg agtgcttgct aagctactaa aaagcccctt atccttgcta
     3721 tcagataaga agctcaatag agtttatagg aatgccaatg tccattagta aaatgctata
     3781 aaacaatagt taaaggggag agaattgaga atagcttaat ttttttggcg ttttggcatg
     3841 actgttacta ggcctgcact tgtcataatc gcaactgcag cagcagtgaa aaatggattt
     3901 gcagtagctt cacctgttga tggtagctgg cctgctggtt ttgcggctgg cttacttgct
     3961 ttttgctttg caaccgagtt cgatgcctga ggagtcttag aacgaggctg tgcctgatcc
     4021 ttaaacttgt cagcaagctc ctgcttcaag cgctcaatgt tagcttgaag atcagcattg
     4081 ctacgatcct tttgctcaag caggctttga agctccttaa ccttagcctc aagctctgcc
     4141 ttgtctgcct taaccacatc aagctcggct gttttttcag ctaattgcgc ttcaaggtca
     4201 gccactctat tattagctgc tgctacctct tgcccaagat ttgatactct tgcattagct
     4261 tcagcaagtg cctgatctgc cgcagctttt tcctttgcaa gcttatcaac attagcctta
     4321 gcacctgcca gctcctcttg aagtgttgtg atgttagcat tagcagtttc aaggtcagtc
     4381 tctgctttaa ccttgtcctg tgttaattga tcaatctcag caagcttctc tgtgagctca
     4441 cgcttagcag agttagtcaa tcgacccaga ctatcaacag cctgacttaa acgatctgct
     4501 tctgcttgag ctactgagag tttgttggca agatcggcag attcactgag agcattatca
     4561 cgatctgatg ttacctcttc cagtttagtg cttaattctt tagaagtaag tttttctctt
     4621 tctatatcgg ctttcaattg agttgtttct gctttcaaag tagcttcaga gtcgatgcga
     4681 gtctttaaat tcgctaaaag ttttgaggaa ataaaattac ttcctttgat accaatagaa
     4741 gaattaatct ttttatctaa actagggttg atttacaact cttcatgttg tttgtttctc
     4801 ctttttattt ttctctttcc cagaccaaag cacctactcc ctaagggaat tacacgttgg
     4861 cctatagcta tattctacct aattttattg gattaacaaa gctcactaat tttacaccat
     4921 gacaagttgt ggctatttta atgaaatata ccgatatcta tcaatagccg atgttcccaa
     4981 gcttgttagt tgttttcgtt tcaaagatac tacccattcg ttttcttaga taatggttaa
     5041 gcttggcgac tataacggtt ggcacaaatc gactaaagaa aaagatatca gcatgctcac
     5101 agcccctaat gaccgtatca gtaataatga cgtcatagtc atgctgtaga cacaaggctt
     5161 ctatggttaa tttatcaaaa atggtaatct caaaaaattc accaatgtat tttttcaaaa
     5221 agcttcccgt actgccatga cttctttcta taatcaagag ctttggtttt ttcatcaatt
     5281 cacacatggt taaaaagaaa ttctcccagg ctatcagcaa ggaataaacc aaattgttga
     5341 gcaaattagt agcaagctcc atatccccgt ccttaaatag cctcttcaca taatcggtaa
     5401 acctaaaata aacataggta taatgctcct taaagaaggc caagtaatcc tttttataat
     5461 cgtaaatcag aaagctttca ctaatatcct ccactcctaa aataacagtg gcatgaagat
     5521 atctggcaac ctcatattta tttggcaata caatacctgt agctccctcc atttcactaa
     5581 gcaaatctat ccagctcagc aaggactgag gacccggaac ctcctcctta accttatcta
     5641 cctgcaagga tttttctaat accaaatcat catctaaata attggaaaac atttctgaca
     5701 agacaagctc atcaagcggt actgaaaatt taagcacaaa caaatgcgac agctttttca
     5761 tctcctgaga atcctgtaac aactccaatg aaagactact cagtgcttta tgcttcccaa
     5821 ttttaaagcc tttgaggtag cgaatgagat taaccgcact taatagcttg agttgacgaa
     5881 aaatcgcaaa atcaatctta acctctatca aagatgccat taattgaaca aattgctcat
     5941 ggtggttttc attaagtaga gaagcaaaag gccattcaga aaaggtatat gcttctgaaa
     6001 aatacttgat gtaaaacagt ctaatattgt attcatctcc aactacacga atgggcttag
     6061 ccgaaatgat aatatcaaaa tgctctttta aatagagatt ggttttacga atcaagcgct
     6121 ttaaggttga caagctaata aaaagtgcct ctgcaagatc atctaatgac gcaaaatcat
     6181 caaaaaacaa ggccgacatc aactgaagag aaggagactc tagcaaggct ctccgataaa
     6241 cctcctttaa gccactttga tgattgtaat gaatatgaaa ttgagaatcc ttgtagaaca
     6301 gcttgcctaa atcttccata aaaacagaat tcgtgataca cgattgcagc gttaaaaccg
     6361 aacaatccag catctgacaa gcatctttat aatataatgg atttttcgtt tcacttaata
     6421 aagtaatcaa ctcaagctct cgccactgct gcttggtaaa gagattctct atagacatgg
     6481 tatctagctc ctaaatatac tcttcctgat taaaaactta ccacaacaca acactatttc
     6541 attaactctt aatgtcggtt gtagaacagt attacattat agcatactat tagccagaaa
     6601 taccttagaa ttgtttgcaa attaaccgat
//
LOCUS       DARYXS010000096         6630 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.097, whole genome shotgun sequence.
ACCESSION   DARYXS010000096 DARYXS010000000
VERSION     DARYXS010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6630
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.097"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..695)
                     /locus_tag="TV193_001668"
     CDS             complement(<1..695)
                     /locus_tag="TV193_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1513842.1"
                     /translation="MLTNQTGYRHRLSKQKLPISMVSCLLGMGVLTSPTLISADDSSP
                     TIIIKSGAGMTIDPQLPKTLLSKPEEKPEETPKLPDERHYGDDVRPEETPKLPDERHY
                     GDDIKPEEMPKLPDERHYGDDIRKPKPEDTPKPPNESGQGNDLKEDLELKKQRRELTE
                     QLRALKTIEEVLEFLRKPIPGFVTDEDWNFLVSFVEKGPENKTFEVDKLKLLEIFSTS
                     QGHRVWLGYLILE"
     gene            complement(781..1938)
                     /locus_tag="TV193_001669"
     CDS             complement(781..1938)
                     /locus_tag="TV193_001669"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678097.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1513843.1"
                     /translation="MMKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTGHVSGEVV
                     EVWPNGQNPNGKIEILSQTEHSEHLQKLRDIEDFQAQKQADHVRYTKWLDGVTVDEHE
                     FRKIKEYDTEYYVTPLLSGKGYYDINKDFNQDSDKCAAAVAANMFHYWFDRNRDSINR
                     FLSQSPGENGVIKLENEKTIEVSKFLETYRSDGDYLDKSPFFDLISNSFKGPVWANKL
                     LDAYINGYGYIHKFAKNTPHSKNNNSKFNFFKKVFDGNLLTDIHQIFDYNTFSDKLSE
                     ALYTGKAIGLAYGPGDLRRSLGHIISVWGADLDDQNRVVAIYVTDSDDKKLTIGNERV
                     GLKRYKVSSDDQGRARLTTRDKDNTGGEIRSIETLDMGTQEWADYFNKTEK"
     gene            complement(2250..3059)
                     /locus_tag="TV193_001670"
     CDS             complement(2250..3059)
                     /locus_tag="TV193_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL1513844.1"
                     /translation="MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYVSST
                     QALRHKDSQLMLEAANQYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIP
                     KVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKL
                     RINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLL
                     VRGHRIKTATPTAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA"
     gene            complement(3140..4582)
                     /locus_tag="TV193_001671"
     CDS             complement(3140..4582)
                     /locus_tag="TV193_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEL1513845.1"
                     /translation="MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYE
                     AYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAAAFAKEAGKHLT
                     ATIAGTGTHAITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVL
                     KKVKDRNDKTGLETGWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSKGL
                     SYNKDAKVYVVNGDTRQDITNSFTVSEDGSSFKINNLKAVQGVTITATSKIVVEYTAT
                     LNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPKGETPKDKVIVFTYKTIINKVDQD
                     QKALKGAGFTLYKLVKGDNGEEKYQIVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGG
                     YNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPS
                     TGSIGTTMLYVFGVMLMTISTLFIFRQKQQ"
     gene            complement(4606..6579)
                     /locus_tag="TV193_001672"
     CDS             complement(4606..6579)
                     /locus_tag="TV193_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEL1513846.1"
                     /translation="MKQLTKIVSVVLLLVFTLSASLHKVRATNLSDNITSLTVASSSL
                     RDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFNKTIPLNIRGVDVGTLEV
                     TLDKAVFTFNQNIETMHDVSGWGEFDITVRNVTQTTAETSGTTTVKVGNRTATITVTK
                     PEAGTGTSSFYYKTGDMQPNDTERVRWFLLINNNKEWVANTVTVEDDIQGGQTLDMSS
                     FDITVSGYRNERFVGENALTEFHTTFPNSVITATDNHISVRLDQYDASQNTVNIAYKT
                     KITDFDQKEFANNSKIWYQILYKDQVSGQESNHQVANINANGGVDGSRYTSFTVKKIW
                     NDKENQDGKRPKTITVQLYANDQKVNDKTIELSDTNSWQASFGKLDKYDSQNQKITYS
                     VKEVMVPVGYQSQVEGDSGVGFTITNTYTPEVISITGQKTWDDRENQDGKRPKEITVR
                     LLANDAATDKVATASEQTGWKYTFTNLPKYKDGKQITYTIQEDPVADYTTTIQGFDIT
                     NHHEVALTSLKVIKVWNDKDDYYHKRPKEITILLKADGKVIREHQMTPDQQGKWEYTF
                     DQLPVYQAGKKISYSIEEKQVAGYQAPVYEVDEGLKQVTVTNTLNPSYKLPDTGGQGV
                     KWYLLIGGGFIIVAILVLISLYQKHKRHNMSKP"
BASE COUNT         1701 a         1429 c         1288 g         2212 t
ORIGIN      
        1 tcttccagaa taaggtaacc taaccaaact ctatgacctt gtgaggttga gaagatttct
       61 agtaatttta atttatctac ttcaaaagtt ttattttctg ggcctttttc tacaaatgat
      121 actaagaaat tccaatcttc atctgttaca aatccaggaa ttggttttct caggaactct
      181 aaaacttcct caatagtttt taaagcacga agctgctctg taagctctcg acgttgcttt
      241 ttaagctcca aatcttcttt taagtcatta ccttgaccgc tttcattagg tggctttgga
      301 gtatcctccg gtttcggctt cctgatgtca tcaccataat gtcgctcatc tgggagcttt
      361 ggcatctctt ccggttttat atcgtcacca taatgtctct cgtctggaag ctttggtgtt
      421 tcttccggtc tgacatcatc accataatgt cgctcatctg gaagtttagg tgtttcctct
      481 ggtttctctt cgggtttaga aaggagagtt ttcggtaatt gaggatcaat tgtcatacct
      541 gcacccgatt taatgatgat agtaggagaa ctatcatcag ctgagattaa tgttggagag
      601 gttagcaccc ccattcctag caagcaggaa accatgctga taggtagctt ctgcttacta
      661 agtctatgcc tgtaccccgt ttggtttgtt agcatcgttt tgttatcgtc ctttccttac
      721 tggctgagtc tattgctgtg tgctttatct ggagtaatca tatatgtgta ggggttattg
      781 ttatttttct gtcttgttga agtaatctgc ccactcttgt gtacccatat ctaatgtttc
      841 aatagatcga atttcaccac ctgtgttatc tttatcacga gtcgtcagac gagcacgacc
      901 ttgatcatcg ctagatactt tatatcgctt caaaccaact ctctcatttc ctatagttaa
      961 ctttttatca tcagaatcag ttacataaat agctaccacg cgattctgat cgtcaagatc
     1021 agctccccag acagaaataa tatgacctag tgaacgacgc aagtctccag gtccgtaggc
     1081 caatccaatg gctttaccag tatagagagc ctcacttaat ttatctgaaa aagtgttata
     1141 atcaaaaatt tggtgaatat ctgtcaagag attaccatca aatacttttt taaagaaatt
     1201 aaatttacta ttattatttt tagaatgtgg agtattttta gcaaatttat ggatataacc
     1261 atagccgtta atgtaagcat ccaatagctt atttgcccaa acaggacctt taaagctgtt
     1321 actgataagg tcaaaaaacg gacttttatc aagataatca ccatcactac ggtaagtttc
     1381 taaaaatttt gatacttcta ttgttttttc attttcaagt ttaataacac cattttcacc
     1441 tggactttga cttaagaaac gattaatact gtctctattt ctatcaaacc aataatggaa
     1501 catattagcc gctacagcgg cagcacattt atcactatct tgattgaaat ctttattgat
     1561 atcatagtaa cctttaccac ttaaaagagg tgttacataa tattctgtgt catattcctt
     1621 gatttttctg aattcatgct catcaacagt taccccatct aaccatttag tgtaacgaac
     1681 atgatcagct tgcttttgag cttggaaatc ttcaatatcg cgtaatttct gtaaatgctc
     1741 agagtgctca gtttgactta gaatttctat tttaccatta ggattttgcc cattaggcca
     1801 aacttcaact acctcaccag aaacatgtcc tgttgttagg aacatcattc ctagcataca
     1861 tgaggcaagg ccaatagata attttctcat accgaattta ggtttacgtg agtgtgtgaa
     1921 tgattgtttt ttcatcatgc tatcctttct tattataaaa cgttttcaaa aacaacaaat
     1981 taaataaata tctaatattt tgtcgttaac tctcctcctt ttatcatttt attaggtttt
     2041 ataagtcaat tttatcatgt tatgctcaga tgtcactttt gaaggctcca aatgctcgct
     2101 cttttaaagc gttttcggtc actaagaaaa aaaaacgatt tctgtgtttt taatcatagt
     2161 cgcaatttag cactaaaaaa tcccctgata ggtcctcagt aacctatcaa gggttgatga
     2221 tttgacttag ttgcttctgg aaagcctgct catgctttag acctcctacg ccagcgccaa
     2281 gtgcctatta gtacgagaga tagccctaat gcactgatta gcaagagcca gaggattagc
     2341 ctactaggct tttgagatcc tcttgcagcg gttggtgtcg ctgttttgat acgatgccct
     2401 ctgaccaaga gccgatgcgt gttgacaccg tagggggtac aggtgaccaa ggttaccaga
     2461 tccttcccct cctctatcct taagaggctg acatcatcag gcaaaacggt agcaatctta
     2521 tccacctgat aggtcatagt cctattaaga ctggtgatgg taaaggtatc gttaatcctc
     2581 agcttatcaa tattggtaaa tagcttggca gagggtaacc ctcgatgtcc tgagatgaca
     2641 gcatgtgttc ccttgccacc tacaggcaaa gaggtgcctg caagatgacc gatagccacc
     2701 tgtaggatct cctcatcggt gccatgataa atcggcagcc gctcatgcac ctttggaata
     2761 tctatgtagg ccatgatacc tgtatttgtc agatccagct gctgctgata ggcttctgcc
     2821 tcactatcgg tcaaggttaa atcaggatca tggttagctt ttagctgctg attgtactga
     2881 ttggctgctt ctagcatgag ctgactatcc ttatgtctca aagcttgcgt gcttgagaca
     2941 tagtcagcga tgagctgtga ttggtgctgt gcattccaat agttactaag ggtggggtaa
     3001 aggacaatca gacagcctgc caccaaaatc acactccaaa aaatgacact tttcttcatt
     3061 ctatagcctc tatcaaaaaa agaggtgaat aggtcttggt aagacgtcta tccacttctt
     3121 tttacctact cacacgatct tattgctgtt tctgacgaaa gataaacagc gttgatattg
     3181 tcattagcat tactccaaac acatagagca tggttgttcc gatacttcct gtcgaaggga
     3241 ggatagaccc ttttttatta acaatagttg cggatacggt accagcttct gtatcagcag
     3301 tgaagccagt tgctttgtca acggttaggc tagtcaactg aggatcgtct gactcggttt
     3361 catgctgcgc tacaatgctg aacatgacat ctgcaatagt gttgtaaccg ccaggtgttg
     3421 ttgtttcgct gagcttgtaa tcaccagcgt caagtccaac aaactcaaag ctagttgtat
     3481 cccctgcttt aatttcttgg actatttgat atttttcctc gccattatca cctttgacca
     3541 gcttataaag ggtaaagcct gcacctttta gggctttttg atcttgatca accttattga
     3601 tgatagtttt ataggtgaaa acgataacct tgtcttttgg tgtctcccct tttggagact
     3661 cctctccttt tccaagagcg tttggatcgt ttgagtattt caaagcaact tcgtttggat
     3721 ttcctttttt gccgatggcc gcttggtcat tgagggtagc agtgtattcg acaacgatct
     3781 tactggtagc tgttattgtt actccctgaa cagcctttag gttattgatt ttaaaagatg
     3841 aaccatcttc actaactgta aatgaattag taatatcttg acgagtatct ccattaacca
     3901 catagacctt ggcgtctttg ttgtagctta gcccttttga taaggtatct acaaattcaa
     3961 ggtagtattc ttgaaaggca tcgtaatttg acggtagggt tgcggttagc tggaatggca
     4021 ccttgtcatt tttgtcatag tcagctgaat cttgccagcc tgtctcaaga cctgtcttgt
     4081 cattacggtc cttgaccttt ttaaggactg ttgggatagc agattttggt ttgaagctgg
     4141 tgtttttaac aaccttcagg acaaatgagg tgtaggcgtc atgcttgcct gtttgagaat
     4201 catttttgtc cttgatgagg tagtagccag cctcgttaac ggtgattgca tgtgttcctg
     4261 ttcctgcaat ggttgctgtc aagtgcttac ctgcttcctt ggcaaaggca gctgcatttg
     4321 cttccttcaa tccctctgca atcttagcag cgtcttttga accatcaaat tcaaaaggtg
     4381 taacaccacc tccccatgtg atgtttgata gggtactgtc aaacaagtca cccttgaaaa
     4441 tctgataagc ctcataggtg tgacctgctg tagctccctc aacagtgatg gtatagcttg
     4501 ctgtatcagc aaatgccttt cctgacagca ttgttaggaa ggtgacaagc aagctcgtca
     4561 agattaattt gattgttttc atagctctct ctcctctatt acatgttatg gttttgacat
     4621 gttatggcgc ttgtgttttt gataaaggct gatcagtaca aggattgcga cgatgataaa
     4681 accgccaccg attaacaggt accatttcac tccttgtcct ccggtgtcag gcagcttgta
     4741 gcttgggtta agggtgttgg ttacagtgac ctgcttcaag ccttcatcaa cctcatagac
     4801 aggggcttga tagccagcaa cctgtttttc ctcaatgctg tagctgattt tcttgcctgc
     4861 ctgatagacc ggcagctggt caaaggtgta ttcccatttt ccttgctgat ccggtgtcat
     4921 ctgatgttca cgaatcacct tgccatctgc ctttagcaaa atggtaatct ccttgggacg
     4981 tttatggtaa taatcgtcct tatcattcca aaccttgatg acctttaggc tggtcaaggc
     5041 tacctcatga tgattggtaa tatcaaatcc ctgaatggtt gtggtgtaat ctgccacagg
     5101 gtcctcttgg atcgtgtagg tgatctgttt accatctttg tatttcggta gattggtaaa
     5161 tgtatacttc cagccggttt gctctgaagc agttgctacc ttgtcagttg cagcgtcatt
     5221 tgccaataaa cgaaccgtaa tctccttagg acgtttaccg tcttggtttt ccctgtcgtc
     5281 ccaagttttt tgaccggtaa tgctaatgac ctctggtgta taggtgttgg taatggtaaa
     5341 tcctactcca ctatccccct caacctgcga ttggtagcca acaggaacca tcacttcctt
     5401 gacactgtag gtaatttttt ggttctgact gtcatactta tccagcttac caaaacttgc
     5461 ttgccagcta ttagtatcac tcaattcaat ggtcttatca ttaactttct gatcattggc
     5521 gtaaagctga acagtaatag tctttggacg cttaccgtct tgattttcct tgtcattcca
     5581 aattttcttg acagtaaagc tggtatagcg actgccatca accccgccgt tagcattgat
     5641 attggctact tggtggtttg actcttgacc cgatacctga tccttgtata aaatctggta
     5701 ccagatttta ctgttgttgg caaattcttt ttggtcaaag tccgttatct ttgtcttata
     5761 agcaatgttg acagtgtttt gtgaggcatc atattgatct aaccgcacac taatgtgatt
     5821 atctgttgcc gtaatgacag aatttggaaa tgttgtatga aactctgtca gagcgttttc
     5881 cccaacgaag cgctcgttac gataaccaga tacggtgatg tcaaagctgc tcatatccaa
     5941 ggtttgacca ccttgaatat cgtcttcgac tgtaacagta ttggccaccc attccttgtt
     6001 gttgttaatc agcaggaacc atctcacacg ctcagtatca ttgggctgca tatcaccagt
     6061 cttataataa aatgagctgg taccagtgcc tgcctcaggc ttagtaacag tgatagtagc
     6121 agtgcgattg cctaccttta ctgtggtcgt tcctgatgtt tcagcggtgg tttgtgtcac
     6181 atttctaaca gtaatatcaa actctcccca accagagaca tcatgcattg tttcaatatt
     6241 ttgattgaat gtgaaaacag ccttgtctag cgtgacctcc aaggtaccaa catctacccc
     6301 tctaatatta agcggtatgg ttttattaaa gccctgaatg tagacattac cacttgtagg
     6361 ccaggtgacc tctatcgtat cccctgcctt gattttctgt tttttgtcat caaacgcaac
     6421 ctttaccgtc gttctctctc catctcggag tgatgaagaa gcaaccgtca atgatgtgat
     6481 gttgtcacta agattagttg cccgaacctt gtgcaggcta gcactaaggg taaagaccag
     6541 caacaagacc acactaacga tctttgtcag ttgtttcaaa caaaatcctc cttttacatt
     6601 attgatttgc aaaatttaat tttacaaatc
//
LOCUS       DARYXS010000097         6525 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.098, whole genome shotgun sequence.
ACCESSION   DARYXS010000097 DARYXS010000000
VERSION     DARYXS010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6525
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.098"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            57..989
                     /locus_tag="TV193_001673"
     CDS             57..989
                     /locus_tag="TV193_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEL1513847.1"
                     /translation="MKKKLSLALSAFLAVFMLVACSNGGNKEAKSDKLKVVVTNSIIA
                     DMTKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADLILYNGINLEDGGQAWFT
                     KLVKNAKKEKDKDYFAVSDGIDVIYLEGESEKGKEDPHAWLNLENGVIYSKNIAKQLI
                     AKDPKNKETYENNLKAYVEKLEKLDKEAKSKFDAIADNKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKDVKPSALFVESSVDRRPMETVSKDSGIPIYA
                     EIFTDSVAKKGQDGDSYYAMMKWNLDKISEGLAK"
     gene            1049..1774
                     /locus_tag="TV193_001674"
     CDS             1049..1774
                     /locus_tag="TV193_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1513848.1"
                     /translation="MIDTQNLSVSYNGNVKALDNISLQIKGPAIVGIIGPNGAGKSTL
                     MKAMLNLLDYSGQVTVDQKDGRRLGHTIAYVEQRSMIDYNFPITVKECVSLGTYTRLG
                     LFRRVGKKEYDQVDQLLEQVGLAGFGNRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIIDLLKDLKKAGKTILIVHHDLSKVEHYFDELVVLNKELIAYGSVD
                     EVFTVETLSKAYGDHLFLGKGMF"
     gene            1775..2608
                     /locus_tag="TV193_001675"
     CDS             1775..2608
                     /locus_tag="TV193_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1513849.1"
                     /translation="MYLKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGINFFVGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGIANSSTDLFHILFGNILAVQDSDKWITIIVSVFVLAIIVLFFKELLIT
                     SFDPVLARSMGMKVTAYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKVMLVISSCLGAMTSVLGLYLGYTFNIAAGSSIVLTSAVVFLISFFVSPKQGYFKKH
                     S"
     gene            complement(2764..3570)
                     /locus_tag="TV193_001676"
     CDS             complement(2764..3570)
                     /locus_tag="TV193_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEL1513850.1"
                     /translation="MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESET
                     AAKAYEAKIKKALKADADQFPQLNKEVDKDEAKVIIKTNQGDITLKLFPKYAPLAVEN
                     FLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS
                     PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSIDNYSKPIIDSYEEGGNPSL
                     DGGYTVFGQVIEGMDIVDKIAASPVGPNDKPIENITINAIDIVKDYSFKK"
     gene            complement(3657..3830)
                     /locus_tag="TV193_001677"
     CDS             complement(3657..3830)
                     /locus_tag="TV193_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513851.1"
                     /translation="MEKEFNTLTYGKLPLQIDMGHGKLIPKGVEVKAIVDMQTGQVTF
                     KVSQEDLEKLRNS"
     gene            3950..6349
                     /locus_tag="TV193_001678"
     CDS             3950..6349
                     /locus_tag="TV193_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEL1513852.1"
                     /translation="MARRTQRQKNPPKRRLTKAELEKQKAIKRMIASFSCALLLVFAM
                     LRLGALGVTLYNLIRFMVGDLANLLMLAVLFYLFFFKWLRQKDGLIAGFIILFLGLLV
                     EWHAYLFSLPQLAHQAIVAGTIQLITNDLLAFKVSEFVGGGMLGAMLYKPISFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKTLFEKLSLAYQENKEKRFVEREKQRLLA
                     EEERLAREALEEQEYLANQAINPETGELLAEPEDLLMEMADQKESEAFFEPEILAYDS
                     HPADDEPEAFGDEEESVPEAPLTGASAIAGEAPLSDDEELSVEVDFTPKTNLLYKLPT
                     IELFAADKPKNQFKEKYLVRQNIKVLEDTFRSFGIDVKVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLADDLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVSFRELWEQSNTS
                     DDKLLEIPLGKAVNGSARSFDLTRMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQV
                     KFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNI
                     AGYNAKVEAYNKQSEQKQIPLPMIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVSFIKEQAEADYDDYFDPGEVSDSDYGSSGAPEGDP
                     LFEEAKALVLETQKASASMLQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
                     N"
BASE COUNT         1788 a         1239 c         1498 g         2000 t
ORIGIN      
        1 atagcataat taactatact taattaatta aataatagat cctaaggaga taactgatga
       61 aaaagaaact tagcctcgcc ttgagtgctt ttttggctgt tttcatgctg gttgcctgct
      121 ctaatggtgg aaacaaggaa gctaagagtg acaagctcaa ggttgtggtt accaattcca
      181 ttattgctga catgactaaa aatattgcag gtgacaagat tgacttgcac agcattgtgc
      241 cgattggtca agatccgcat gagtatgagc cattgccaga agacgttgag aagaccagca
      301 atgccgatct tattctctat aacggtatta accttgaaga cggcggacag gcttggttta
      361 caaagcttgt aaaaaatgct aagaaggaaa aggacaagga ctacttcgct gtatctgatg
      421 gtattgatgt gatttaccta gaaggtgaaa gtgaaaaagg caaggaagac cctcatgctt
      481 ggttgaatct tgaaaatggg gttatctatt caaaaaatat tgcaaagcaa ttgatcgcta
      541 aagaccctaa aaacaaggaa acctatgaaa acaacctaaa agcttacgtt gagaagctag
      601 agaagcttga taaggaagca aaatcaaaat ttgatgctat tgctgacaat aaaaagctaa
      661 tcgtcacaag tgaaggctgc ttcaaatact tctcaaaagc ttacggtgtc ccatcagcct
      721 acatctggga aatcaacact gaagaagaag gaactccgga tcaaatttca tcattgatcg
      781 aaaaattgaa agacgttaag ccatcagcgc tttttgttga gtcaagtgtt gacagacgtc
      841 caatggagac tgtttctaag gacagtggta ttccgatcta tgcagaaatc tttactgact
      901 ctgtagccaa aaaaggccaa gatggagaca gctactatgc catgatgaaa tggaaccttg
      961 ataaaatttc tgaaggctta gcaaaataat ataacaataa agcacagcag cttctggtgt
     1021 tgtgctttgt ttgtattaag gagaaaaaat gattgatacg caaaatcttt cggttagcta
     1081 taacggtaac gtaaaagcct tagacaatat ctcactacaa atcaaaggac cagctatcgt
     1141 tgggattatc gggccaaatg gtgcaggaaa atcaaccttg atgaaggcta tgctcaatct
     1201 tttagattat agtggccaag taactgttga tcaaaaggac ggtcgaaggc tggggcatac
     1261 gattgcttat gtagagcagc gcagcatgat tgactacaac tttccaatta cggtgaagga
     1321 gtgcgtctca ttagggacct acactaggct agggcttttt cgtcgtgtcg gaaaaaaaga
     1381 atatgatcag gttgaccagc tgctagagca ggttgggctt gctggctttg gtaatcgtcc
     1441 gataaaatct ctttctggtg gtcagtttca gcgtatgcta gtagctagat gcttgattca
     1501 ggagtcagac tatatttttc ttgatgagcc ctttgttggg attgattcgg ttagtgaaaa
     1561 aatcatcatt gacctgctca aggacttgaa aaaagcaggc aaaacgattt taattgttca
     1621 tcacgattta agcaaggtag agcattactt tgatgagtta gtggtattga acaaagagct
     1681 gatcgcttat ggatctgttg atgaggtgtt cactgttgaa accctatcaa aggcctatgg
     1741 tgatcatcta ttcttaggaa agggaatgtt ttaaatgtat ttgaagtttt ttgagggcct
     1801 gatgtcctat cattttttac aaaatgccct tattacagcc gttgttattg gtattgtatc
     1861 aggagcagta ggctgcttta ttatccttag gtccatgtca ttaatgggtg atgcgatttc
     1921 tcacgctgtt ttgccaggag tagccttgtc ctttatttta gggattaatt tttttgtagg
     1981 ggctattgtc tttggcttgc tagcctctgt tatcattacc tacatcaagg aaaactctgt
     2041 tatcaaggga gacacagcaa tagggataac ctttagctct tttcttgcct taggggttat
     2101 tctgattggg attgctaata gctcaacgga tctttttcat atcctctttg gaaatatcct
     2161 agcagtgcaa gacagtgaca aatggattac gatcattgtt tcggtttttg ttttggctat
     2221 tattgtcctc ttctttaagg aattactcat tacctccttt gatcctgtgc tagcaaggtc
     2281 tatgggaatg aaggtcactg cttatcatta tctgttgatg attttgttga ccttggtttc
     2341 ggtgactgct atgcaaagtg ttggtaccat tttgattgtg gcgatgctga ttacgccagc
     2401 ggctacagcg tatttgtatg ctaacagcct aaaggtaatg ctggttatct cctcatgctt
     2461 gggagctatg acctctgtgt tggggctcta tttgggctac acctttaata ttgcagcagg
     2521 ctcaagcatt gttttgacct cggctgtggt gtttctgatt agcttctttg tttcgcctaa
     2581 gcagggctac tttaaaaagc attcctagta aaccatagct ggctgtgaat ggatagctgc
     2641 taatgatatg atcaataggc tagcttcttt atttaattga tagcaaaaaa tcacgaccag
     2701 ctcttgaatc ggtggctttt ccgataagga gctggtcgtt ttattgttgt tgtagcttag
     2761 aggctatttt ttaaaggagt aatccttaac aatgtcaata gcattaatag tgatgttctc
     2821 tattggtttg tcatttgggc cgactgggct ggcagctatt ttatcaacga tatccatacc
     2881 ctcaataacc tgaccaaaaa cggtatagcc accatctagg ctaggattac ccccttcttc
     2941 gtaggagtca atgattggct tagagtaatt atcaattgat aaggccttgg cttggttgag
     3001 cttgctttga ttgatgaaga actggctgcc attagtatct gcaccggcat ttgccatagc
     3061 aagagcccct cgaatgttat ataaaaatgg tgagatttca ttagcaaagc cttgtcccgc
     3121 atcttttttg ctgtccttgc ccttccaaat ggattctccg ccagatccat ctccctttgg
     3181 atcaccggtt tgaatcataa agttattaat cacccgatgg aacaaaagtt tgtcgtaata
     3241 gccttccttg gcgtgtgtta aaaagttttc aacagcaagc ggtgcatact tggggaagag
     3301 cttgagggtg atatcgccct gattagtttt gataatgacc ttagcttcgt ctttgtcgac
     3361 ttctttattt aattgtggaa actgatcagc gtcagccttg agtgcttttt tgatttttgc
     3421 ttcataagcc tttgctgctg tctcgctttc ctctctagcg attttttcat cgacgtattc
     3481 atcaccttta atagcacgat caatggactc acagccactt aagctaagca aagcaagacc
     3541 gattaagcca aaagatagta gttttttcat gtgtactcct tagaacaatt tcttttattt
     3601 taacataaaa tgacttggaa aataaagcta aagggcattg agacgaagtc tattttttaa
     3661 ctatttctaa gcttctctaa gtcctcctga gaaaccttga aggtgacttg cccggtctgc
     3721 atatcaacga tagccttgac ttcaactcct ttgggaatta gcttgccatg ccccatatca
     3781 atttgcaggg gaagcttacc ataggtcaag gtgttaaatt ctttttccat cttcaactcc
     3841 tatttgttct tatgattgac attatagcat aaaatcaagc agcttcatct atttattgag
     3901 aattttaatg tcatctttca taacgattaa aaaatgttat aataaggcta tggctagaag
     3961 aactcaacga caaaaaaatc cccctaagag acgtttaaca aaggcagagc ttgaaaagca
     4021 aaaggctatt aagagaatga ttgcttcttt ctcctgcgct ttattgcttg tttttgccat
     4081 gcttcgctta ggtgcgcttg gggttacctt atataatctt attcgcttta tggttggcga
     4141 cttagccaat ctcttgatgt tggcggtcct tttttacctc tttttcttca agtggctcag
     4201 gcaaaaagat ggccttatcg ctggctttat catcttgttt ttagggcttc tggttgaatg
     4261 gcatgcctat cttttctcat tgcctcagct agctcatcag gctattgttg ctgggactat
     4321 ccagctaatc accaatgacc tgctagcctt taaggttagc gagtttgttg gtggtggtat
     4381 gcttggggcc atgctgtaca agcctatttc cttcttgttt tctaatattg gctcttattt
     4441 tattggtttt ttgtttatcc tgctgggctt gtttttaatg accccttggg atatttatga
     4501 cgtcagtcat tttgttaaga cgctttttga aaagctatcc ctggcctatc aagaaaacaa
     4561 ggaaaagcgg tttgttgagc gagaaaagca acgattgctg gctgaagagg agcgtctagc
     4621 aagagaggcc ttggaggagc aagaatatct ggccaatcaa gcgattaatc ctgagacagg
     4681 tgagctttta gcagagccag aagacctatt gatggagatg gctgatcaga aggagtctga
     4741 agcatttttt gagccggaaa ttctggccta tgactcacac cctgctgatg atgagcctga
     4801 ggcatttgga gatgaagagg agtctgtacc agaagcccct ctaacgggtg cttcagcaat
     4861 cgcaggagag gcgccgctgt cagatgatga ggagctgtca gtggaggtcg atttcacgcc
     4921 aaagaccaat ctgctttaca agctgccgac gatagagctg tttgctgctg ataagcctaa
     4981 aaatcaattc aaggaaaagt accttgttcg tcaaaatatc aaggtattag aggatacctt
     5041 cagaagcttt ggaattgacg tcaaggtgga gcgggcagag attgggccat ctgtaactaa
     5101 atacgaggtt aagccggctg ttggtgttcg tgtgaatcgc atttccaatt tagctgatga
     5161 cttggccttg gccttggcag ccaaggacgt acggattgaa gctccgatcc ctggcaaatc
     5221 ccttgtgggt atagaggtac caaattcaga ggttgcaacg gtttctttcc gcgagctttg
     5281 ggagcaatcc aacacatctg atgacaaatt attggaaatt cctcttggta aggctgtcaa
     5341 cggtagtgcc agaagctttg atttgacccg catgcctcat ttgctggtgg ctggctcaac
     5401 aggatcaggg aaatctgttg cagtcaacgg tattatctcc agtattttaa tgaaggctag
     5461 accggatcag gtcaaattcc taatggtcga tccgaaaatg gttgagctgt ctgtttataa
     5521 tgacattcct cacctgttaa tcccggtggt caccaaccct cgtaaagcaa gcaaagcgct
     5581 tcagaaggtt gttgatgaga tggaaaatcg ctatgagctg ttcagtaagg tcggtgtccg
     5641 aaatattgca ggctacaatg ccaaggttga agcctacaac aagcaatctg agcaaaagca
     5701 aatccctttg ccgatgattg ttgttattgt tgatgagcta gctgatttga tgatggtggc
     5761 tagtaaggag gttgaggatg ctattattcg tcttgggcaa aaggcgcgtg cagcaggtat
     5821 ccatatgatt ttagctactc agagaccttc tgttgatgtt atttctggat tgattaaggc
     5881 taatgttcca tcacgtattg cctttgcggt ttcatcagga acagatagtc gcaccattct
     5941 tgatgaaaat ggcgctgaaa agctgcttgg tcgcggggac atgctcttta agccgattga
     6001 tgagaatcac cctgtgcgtc tgcaaggctc ctttatttca gatgatgatg ttgagcgcat
     6061 tgttagcttt atcaaggagc aggcagaggc tgattatgat gattattttg atccgggtga
     6121 ggttagtgac tctgattatg gcagcagcgg agctcctgag ggtgatcccc tttttgagga
     6181 agcaaaggct cttgtattgg aaacgcaaaa ggcaagcgcc tcgatgctcc aaaggcgtct
     6241 atcggttggc tttaaccgag caactcgact aatggacgaa ttagaagagg ccggtgtcat
     6301 tggtccagct gaggggacta agccaagaaa ggtactgcaa accaattaaa aaagagctca
     6361 tctaaaggct catcataaaa caaacccgta ccaagctaag cttaaccatg tggcttgata
     6421 cgggtttttg atatgctgct ttgaaaaagt cccactcaag cagaaaactc aaagacagct
     6481 tcattttgag tgatagtgct agagctaatt ggcagatcta atctg
//
LOCUS       DARYXS010000098         6422 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.099, whole genome shotgun sequence.
ACCESSION   DARYXS010000098 DARYXS010000000
VERSION     DARYXS010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6422
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.099"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(223..603)
                     /locus_tag="TV193_001679"
     CDS             complement(223..603)
                     /locus_tag="TV193_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEL1513853.1"
                     /translation="MIKVFETRVTAIGSEAADMISAANMLILFDQGAPADLADFCYTI
                     DNKQVSGSISAGGQLVIDQMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLH
                     VKGKGLPQVRQGSLVQIFAWLRCS"
     gene            complement(637..1629)
                     /locus_tag="TV193_001680"
     CDS             complement(637..1629)
                     /locus_tag="TV193_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEL1513854.1"
                     /translation="MTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIVD
                     KIAALTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGPL
                     AQYITEDIYVSAVGLEQITASDAQAHVASAKESSVPKASSYDTSKKITEQRAESSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            complement(1645..2190)
                     /gene="srlA"
                     /locus_tag="TV193_001681"
     CDS             complement(1645..2190)
                     /gene="srlA"
                     /locus_tag="TV193_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677306.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEL1513855.1"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMVLPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYLLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKMIEL"
     gene            complement(2326..2787)
                     /locus_tag="TV193_001682"
     CDS             complement(2326..2787)
                     /locus_tag="TV193_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HEL1513856.1"
                     /translation="MSFMVIFGLFVIVAYLFQLLLGLRQLKHFNAVYASLRRQGRVAI
                     GRRAGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPL
                     IRRENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWTLQAKQLLARFK"
     gene            complement(2787..4559)
                     /locus_tag="TV193_001683"
     CDS             complement(2787..4559)
                     /locus_tag="TV193_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1513857.1"
                     /translation="MSNAASSIGQLNDILDGDATITQQGAFLQLQVYDYARLETILAG
                     SLRKASDFNSASKRVAYLLKRLLQSSSALVIDDLADEIGVSRSTINKDLKAAKALART
                     YSVMIQGKPNHGIQAVGTELNLRLLYVHEVYKYFEPQGLCGDSLFFLDELYQTYQLPR
                     KIQELLTKSFAITIERMRQGRYLTDPIPYYSNEVDSSAFMEELVYHIELAYQLSLSQY
                     ERQFISFPLNIQYIEDLAYQEKPLQQSIVRLYSKMIEHIKTSLLVTIDQDKLFVALHT
                     HLKLLVNRLIFHVQANDIFHGEIRYKYPLAFDMAIVAAQVLAEEFDCAIELSECSYLA
                     LYFEMMMKDAEHVTEPTVKKIAVVCTTGRGTANMICRRLSKVLGPDLLISQFSEEQFN
                     PDDNDHYFAIFTTVPLKFGQLKSPVLQITNLFDDQWLQNEWRRVHHYHQKNLATITLH
                     FARLSKGKAYTDYLTEMAELLEEKQLVDRQFGQRLLEREALQSTLFGNRIAFPHTIND
                     KETKTVLLLGLLDEPYREHDCLVEFIFLVAISKRVEAQMEADLLKIYDDIFKIASDDK
                     LQAELRSLKSQAEFIAFTKEKGVF"
     gene            complement(4853..6202)
                     /locus_tag="TV193_001684"
     CDS             complement(4853..6202)
                     /locus_tag="TV193_001684"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEL1513858.1"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
BASE COUNT         1869 a         1545 c         1289 g         1719 t
ORIGIN      
        1 aattaattaa ataatcaact aatgtacaag ttgtctttaa gctgaaaaga ggctatcaac
       61 agcctctttt tttgatgata tagataagcc caatgcttcc ttagaagagc tcttctgtga
      121 gatgacctta tcacctgaca ttagctgctt ggctcatgcc tacagctaaa ggaaatgccc
      181 tgcaaggata gcagcactta gcctgctggt ctacggcgtg tctcagctgc acctaagcca
      241 agcaaagatt tgtactaggc tgccctgcct gacctgtggc agccctttgc ccttgacatg
      301 cagagtaccg ggaagagagc tggctgtgga gccatcaaaa gaaatggtta tatgccctag
      361 ctgagcaaga tttttttcaa caacagcacc tactgctgtg atgtcatatg ccatttgatc
      421 aatgactagc tgaccaccag cagagataga cccagacact tgcttgttgt caatcgtata
      481 gcaaaagtct gccaagtctg ccggtgctcc ctgatcaaaa agaataagca tattggcagc
      541 actaatcatg tctgccgcct ccgatccaat agcggtaact cttgtttcaa atacttttat
      601 catacattct ctctcttcct atcatacgat agctccttac tgatacaaac caatacttgc
      661 aatccaagca acaacaaccc gaggaacacc atttaaaaag cgtgaataaa gcacagatgg
      721 caccccaacc tctactgtct cagcattagc ctctgataaa ccaagcgcta ctggaatgaa
      781 atcacagcca ttttgcgtat taatagcaaa aagtgcagga agagccattt gtggtggaat
      841 agtgcctttt ccaatctcaa caccaatgag cgttccgatg atttgactaa taaccgcacc
      901 aggtcctaac agcggtgata aaaatggcaa cgaacagata aagccaatga taatcaagcc
      961 ccaaatatta ccagccagcg gtaccatgag cttggctagc caattaccaa caccagagcc
     1021 ttggataaaa ccaattaaaa gagagacaaa tgccatgaat ggcaaaatcg tattgattaa
     1081 ggtctggata gcctcacgcg ccgcttggtt gaagatagca actaccttac ctgctcccat
     1141 accaatgcgg gcaacaaagc tgctttctgc gcgctgctca gtaatctttt tgctagtatc
     1201 atagctgcta gcctttggaa ctgatgactc cttagcacta gcaacatgag cctgagcgtc
     1261 actggctgtg atttgctcaa gacctacagc agacacgtaa atgtcctcgg taatgtactg
     1321 tgccaaggga ccgcttttac ctgtcgccac gatattaatg gttggaatgc cttttttagg
     1381 gtaaataccg cagcgtaggg tgccgccaca atccacaata gctagggcta tctcatcatc
     1441 agggattgag gtcacaaagc cattgaccgc ctccatacct gttagggcag caattttatc
     1501 gacaatgtca ggcttttttc caccgccagt aatatagata aatttgtgct tagcttctgt
     1561 tggtgtaatg gttagcggcc caccatagcc accgctcccc ttaacaactg taatactgtg
     1621 ataagtcatc atgctacctc tcttctataa ttcaatcatc ttacttaatg tcacaccctg
     1681 ctgcttggcc acgtaggctg tcgtaaagtc agttacccag ccaccaacaa agttcatgat
     1741 taacccaacc aagaggtaac gaatcgccaa gtccatttgg ctcaagccta gcgtcttgat
     1801 acctgaggca atacctaacc agacaaacaa ttctcccgga ttaatgtgtg gaaagacacc
     1861 gtttgacgta tgacaaaatt gcatttgagc ggcaacatag cttggcttgt aatactcggg
     1921 cataaagcgt cccatgctga ttgccatcgg attacccagc ataaaagctg aaataaaagg
     1981 caataccatg tagcgactga tagggttttt agcagagatt tttgccaatt gattgaccct
     2041 ttgatctcct aaaataccaa ttaaggcatt cattgcaacc agcagcatca agaccaccgg
     2101 cacaatgcca gtcatccagc tgacaaaggt ttcaccacca agctggaaga gcttcataaa
     2161 gccttccgca aatcttgtta tcatttccat aaataaactc ctcatatgat gtacttacaa
     2221 gcaagacaat acaaatgtac tgcctgcttg ataatagctg cttgagctgg actcaaaaca
     2281 gcttttatgt tgacaaggca agcaatcaat cctgcttttg gcaccttact tgaagcgtgc
     2341 cagcagctgc ttggcctgta gggtccaatc aaaggctgag gcatattttg gtgcgtcctc
     2401 atagacccct gcctcaaccc tcaagaagac ctctcttgcg tcctcaatag ccaagcgcag
     2461 caatttattt tctcgtctaa tcaagggatt gtagcgatca aaataatgaa tatcctgacc
     2521 gatataagct ggcattggct taaacctggc tgccactgtc acaccctgca tttgcctagc
     2581 atctaatacc ttacctgact gatccaaggc aaacatgaca atggttccgg ccctgatttt
     2641 cccggctcta cggccaatag caacgcgccc ctgtcgtcta agactggcat aaacagcatt
     2701 gaagtgctta agctgtctca gacctagcaa taattgaaaa aggtaagcaa ctatgacaaa
     2761 tagtccaaaa ataaccataa aactcattaa aaaactcctt tttccttggt aaatgcaata
     2821 aactcagctt gactttttag gctccttagc tccgcctgaa gcttatcatc gcttgctatt
     2881 ttgaaaatat catcataaat tttcaagaga tcagcctcca tctgcgcttc aaccctcttg
     2941 gaaatagcca ctagaaaaat aaactccacc agacagtcat gctcacgata aggctcgtct
     3001 aatagaccca gcagcaggac agtctttgtt tccttgtcat taatcgtatg tggaaaggca
     3061 atgcgattgc caaataaggt tgattgcagg gcctcacgct ctagcaggcg ttgaccaaac
     3121 tgcctgtcaa ccagctgctt ttcctcaagc agctccgcca tttcagtcag gtagtcagtg
     3181 taggccttcc cctttgacag acgagcaaag tgtagggtga tggtcgccag gtttttctgg
     3241 tgataatgat gtaccctgcg ccattcattt tgcagccact ggtcatcaaa cagatttgtg
     3301 atttggagaa caggagattt tagctgacca aacttcagcg gcacagtggt gaatatggca
     3361 aaatagtgat cattgtcatc aggattgaat tgctcctcag agaattgtga gatcaacaaa
     3421 tcaggaccta gcaccttgct caagcgacga caaatcatat tggcagtgcc acgacctgtc
     3481 gtgcagacaa cggcaatttt tttcactgtt ggctctgtca catgctcagc gtctttcatc
     3541 atcatttcga aataaagggc caaatagcta cactcagaca attctatggc gcagtcaaac
     3601 tcctctgcta agacctgagc tgcgacaatg gccatatcaa aggccaaggg gtatttgtat
     3661 ctaatttctc catgaaaaat atcattggcc tgaacatgaa aaatcaaacg attcaccaag
     3721 agcttcaaat gcgtatgcaa agcaacaaaa agcttgtctt ggtcaatagt caccaagaga
     3781 ctggtcttga tgtgctcaat catttttgaa taaagcctga caatgctctg ttgcagaggc
     3841 ttttcttgat aggctagatc ctcgatgtat tggatattca agggaaagct aataaactgg
     3901 cgctcgtatt gactcagtga cagctgatag gctagctcaa tgtgatagac cagctcctcc
     3961 ataaaggcac tggaatcaac ctcattgcta tagtaaggaa taggatctgt cagatacctg
     4021 ccctgacgca ttcgctcaat ggttatcgca aagctcttgg tcaaaagctc ttggattttg
     4081 cgaggaagct ggtaggtctg atacagctca tctagaaaaa acaagctatc accacacaag
     4141 ccctgcggct caaagtattt gtaaacctca tgaacataaa gcagccgaag gttcaactca
     4201 gtgccaacag cctgtatgcc atgattgggc ttgccctgaa tcatgaccga ataggtccta
     4261 gcaagagcct tggctgcctt taggtcttta ttgatcgtgc tgcgactgac gccaatctca
     4321 tcagccaaat catcaatgac taaagctgag gagctttgca gtagcctttt tagaagataa
     4381 gctacccgct tgctagcgga attaaagtca ctagccttac gtaaactacc agctaatatc
     4441 gtctctaatc tagcataatc atagacctgc agctgcaaaa aggcgccttg ttgggtgatg
     4501 gtcgcatctc catctaaaat gtcattgagc tgaccaatgc tacttgcagc gtttgacatc
     4561 gtcttttcac aaagtcacag cttagaaagc tagcagagga gacaaaagca agaccttatc
     4621 agctaacagc agcatattaa acgaacagct agtgatactg atcctactaa gcatagagct
     4681 ccaaaagcct ggcttaaata gtattcaaaa tagaacaaga gctctcaaga acaataacct
     4741 agcgcactac ttgccttgat aagcctaacc gaccttgaaa agaagcaaaa aaaagagcct
     4801 ctcacgagac tctttgttat gttttagcag actagtctag ctagctctgt cattacaagc
     4861 gtgcgttgag cgctgctcct agctcttcaa agcctggctt accaagaagg gcaaacatgt
     4921 ttttcttgta agcctcaaca cctggctgat caaatggatt taccccattg aggtagcctg
     4981 aaagggcaat agcaagctca aagaagtaga tcgtatagcc tagtgtaaat tcgtcttgct
     5041 ctggaagcgt gataaacata tttggcacac caccgtctgt atgggcaaga aggacaccat
     5101 ctgttgcttt tttgttgaca aagtcaacgt ctttgccttg taggtagcca aggccatcaa
     5161 gatcctcagc catttctggg ataatcacat tttgacgtgg cttatccaca cgaatcactg
     5221 tctcaaagag gttacggtag ccttcttgga taaattgacc aagagaatgc aggtctgtcg
     5281 agaaattagc tgaagttggg taaataccct tttggtcctt tccttcagac tcaccagcca
     5341 gttgcttcca ccattcgcta aaatactgca atgatggctc atagtttgcc aaaatttcag
     5401 ttacatagcc tttgcgatag aggatattgc gaactacagc atattggtaa gcgatgtttt
     5461 ctgagatttt atctgatgac aggtccttac gagctgcatt tgccccctcc atcagcgcgg
     5521 taatatcagc acccgatgct gcaattggca acaagcccac agctgtcagc actgaaaaac
     5581 gaccaccaac attatctggc acaacaaagg tttcccaatg atttgcatca gcctcaacct
     5641 taacagcacc cttgacctta tcagtcgttg catagatacg cttgttggcc tcttcttgac
     5701 cgtacttttt aacaagtaat tctttaaaga cacgaaaggc gattgcaggc tctgttgttg
     5761 taccagactt agaaatcacg ttaacagaga aatctttatc ttgaacatag tccacaagat
     5821 cagcaagata gcttgatgag atggagttcc cagcataaag aatttgtggt gctttgcgct
     5881 cttttgctgt ttgtaggttg gcaaaatggc tgttcaaaaa gtcaatcgca gccttagcac
     5941 caaggtaaga gccaccaata ccaatcacaa caagaacgtc actgtcagcc ttaatcttct
     6001 cagctgcttt aaggatacga gcaaattctt ctttgtcata gttttcaggt aactcaagcc
     6061 agcccaagaa atctgatcca ggtccagtgc cctgacgtag tgcctgatca gcctctgtta
     6121 cctgaccttg taaaaagtca atttcatgct gtccggcaaa ttgctcaaga acctttgaat
     6181 aatcaaatgt aatatgtgac attattttac tcccttaact tttaaagttt cattagtatc
     6241 ataacctttt ctattcaata tttcaatgtt ttttattttt ggggagggtg gcctgacttt
     6301 aacgacatga ggatcatttc tgtctaaaag cagctttgtg atgagcctag cgcttcccta
     6361 tctgcttcta ctatagctta ctggggctga tccgggtgat gtggtagcct cttggcatag
     6421 cc
//
LOCUS       DARYXS010000099         6372 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.100, whole genome shotgun sequence.
ACCESSION   DARYXS010000099 DARYXS010000000
VERSION     DARYXS010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6372
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.100"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(57..260)
                     /locus_tag="TV193_001685"
     CDS             complement(57..260)
                     /locus_tag="TV193_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEL1513859.1"
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSG
                     PLYVLGAGIGCIVGAGQAIINGL"
     gene            complement(277..534)
                     /locus_tag="TV193_001686"
     CDS             complement(277..534)
                     /locus_tag="TV193_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1513860.1"
                     /translation="MNTETINQFDVMNIEALATVEGGYSGKDCLKDMGGYMLIGAGSG
                     ALWGAPAGGIGVLPGAFVGAHVGAIGGGFACMGGMIGNRFN"
     gene            complement(855..2222)
                     /gene="rlmD"
                     /locus_tag="TV193_001687"
     CDS             complement(855..2222)
                     /gene="rlmD"
                     /locus_tag="TV193_001687"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1513861.1"
                     /translation="MNVKIKQKIPLKIKRMGINGEGIGFYKKTLVFVPGALKGEEVFC
                     QVTAVKRNFAEARLLVINKASKNRVKPACSIYETCGGCQIMHLAYPKQLYFKDDIIRQ
                     ALKKFKPKGYEEFEIRHTLGMAEPQHYRAKLQFQTRSFGGSVKAGLFSEGSHCLVAID
                     DCLVQDQLTQAIVNHVTQLLDRYRIPIYNERRVAGIRTVMVRRAQASDQVQLIFVSSK
                     EVRLAGLIAELTAAFPQIRTVALNINTSKTSDIYGAKTEILWGQETIQEEVLSHSFAL
                     SPRAFYQLNPTQTEVLYSQVVQALEPTAEEHIIDAYCGVGSIGLAVANKVRSVRGMDI
                     IPEAIADARKNAQALGFDNAYYETGKAEELIPSWYAEGYRADALIVDPPRTGLDDKLL
                     QTILHYQPAKMVYVSCNTSTLARDLVPLVQVYDVIYIQSVDMFPHTARTEAVVKLQKR
                     QKPQQ"
     gene            complement(2219..3187)
                     /locus_tag="TV193_001688"
     CDS             complement(2219..3187)
                     /locus_tag="TV193_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1513862.1"
                     /translation="MTEKDKKDRDKVVSLQHYRQADAEDDMLFGHETEFFSDDLEALL
                     NSMDNQLLSDLEHFAGDRAYDLIKYLAFDEDCQHQAWLASKPMGWVNLEERPYLSQKF
                     ELAMLYKQNGLYEKALHHLLEIHQYDEGDHLGTRYEILALYVLKSDFTMAEAFYDSKD
                     YHRGDLLMEVPLMVGALLAEREELADDILANLAETVPDFVAIVRQKAFPIDDILAAGA
                     LESYEPNSLSSIYLAFFNILPLLMTAQYYLQHYVQEFFEGAEGELTFLEELDLPLSKV
                     NLFNQYGIHTLEDFSAWTTQELLDIPGVGKQMIARLKRLGVIFSQE"
     gene            3251..4027
                     /gene="recX"
                     /locus_tag="TV193_001689"
     CDS             3251..4027
                     /gene="recX"
                     /locus_tag="TV193_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEL1513863.1"
                     /translation="MKISQIEKKKHLYLIKLDNGDSLTVTEDTIVTFMLSKHMVIDSQ
                     QWEDIKSFAQFSYGKSKALGFIAFQQRSQKQVQDYLLKHQISPDLIPSIIDSLKQGKW
                     IDDQQYVDTYIRQNSLTGDKGPLLLKQKLMLKGIASQLIEPVLAQTDFSSIAQKAAEK
                     IYQKYQHKLPSKALTDKIIQGLLNKGFSYDLAKGIVSQLSLEQDSQHIEDLLDQEFDK
                     LLRKYSRRYDGYQLKQKLYQALYRKGYDSDDITTKLNDYF"
     gene            4260..4793
                     /locus_tag="TV193_001690"
     CDS             4260..4793
                     /locus_tag="TV193_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEL1513864.1"
                     /translation="MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFS
                     KAYVSIWYKRYLELKNR"
     gene            5043..5354
                     /locus_tag="TV193_001691"
     CDS             5043..5354
                     /locus_tag="TV193_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEL1513865.1"
                     /translation="MAFQATKGRYASFGVAVSLPPELIDTFWEIIDHYLKGVFPLNTV
                     LTFRLIKNKKNLSYEYIDQQAGLRIVFDYNTPFNAFYPKTLYIVNQQGIETILLPHEM
                     Y"
BASE COUNT         2016 a         1465 c         1060 g         1831 t
ORIGIN      
        1 caccaaatat caatagtata atcggaacta aaactaatac tactaataat attgttttat
       61 aatccattga taatggcctg tcctgcacca acaatgcatc ctattcctgc acccaataca
      121 tacaatggac cagagaaagc acctgtaacg attgctccac ctgcacaatg ccctgcaaca
      181 gagccccaat taattttacc gccatttaca cttgccaaat caagctcata taacatctga
      241 aaatcttcgt actgcttcat ggtatatact cctttcttag ttaaatctat tacctatcat
      301 tccacccatg catgcaaaac ctcccccaat tgcaccaaca tgtgcaccaa caaatgcacc
      361 tggaagtacg ccaatccctc ctgctggggc accccacaaa gccccacttc cagctcctat
      421 taacatatat cctcccatgt ctttaagaca gtccttacca gaatatccac cttcaacagt
      481 tgcaagagcc tctatattca taacatcaaa ttgattaatc gtttctgtat tcattttgaa
      541 tacctccata acatattttt tctttatgtc gcgatcacga tttaagtata gcattctagt
      601 atcatatttt ttctaaaagt cttaaacggt cgttttttca tcgtaaacgg tcattttcaa
      661 tcgttttcaa ccgttcaaga caaaattaac taccattcag gattttcatt ggataaatag
      721 ctattttttg gctctttgcc aacccactaa agctattaat aaaaaaataa gacagtagtc
      781 acatttaggc tactgtctct tttatctaaa gccttgatcg gtaagaaaag agccagtctt
      841 ttccaactaa tcgattattg ttgtggtttt tgtcgctttt gtagcttcac tacagcctcg
      901 gtccttgctg tgtgtggaaa catgtcaaca gattgaatat atatcacatc atagacctga
      961 accaagggta ccagatcacg agccaaggtt gaggtattac aggagacata aaccatttta
     1021 gctggctgat agtgtaaaat cgtttgtaat agcttgtcat ctagtcctgt tcgaggtgga
     1081 tctacaatca aggcatcagc tcggtagcct tcagcgtacc agcttgggat cagttcctct
     1141 gccttgccag tctcataata agcattgtca aagcccaatg cctgcgcatt tttcctagca
     1201 tcagcaattg cctctggaat aatatccata ccacgaacag atcttacttt gtttgcaact
     1261 gccagaccaa ttgagccaac accgcaataa gcatcaataa tatgctcctc agctgtgggc
     1321 tcaagcgcct gaaccacttg actatataaa acctctgtct gtgtgggatt aagctgataa
     1381 aaggctcttg gcgacagggc aaagctatgg ctcaaaacct cctcttgaat ggtctcctga
     1441 ccccagagaa tctcagtttt ggcgccataa atatcactcg tttttgaagt attgatgttt
     1501 aaagcaacag tcctgatttg tggaaatgca gcagtcagct cagcaataag acctgccagc
     1561 ctcacctctt tactgcttac aaaaatcaac tgaacctgat cactggcctg tgccctacga
     1621 accataactg tacgaattcc agctactctg cgttcattat agataggaat cctataccga
     1681 tcaagcagct gagtcacatg attaacaatc gcctgtgtta gctgatcctg aaccagacaa
     1741 tcatcaatgg caaccaagca atggctccct tctgaaaata agcctgcctt gacggagcca
     1801 ccaaacgaac gcgtctgaaa ctgtaatttt gctcggtaat gctgcggctc tgccattcct
     1861 aaggtatgac gaatctcaaa ctcttcatac cccttaggct taaacttttt taaggcctgc
     1921 cgaatgatgt catccttaaa gtagagctgc ttaggatagg ccagatgcat gatttgacag
     1981 cctccacagg tctcataaat ggaacaggcc ggcttcaccc ggtttttaga agccttatta
     2041 atcaccaaga gccttgcctc agcaaaattg cgcttaacag cagtcacttg acaaaaaacc
     2101 tcttctccct tcaaggctcc gggaacaaag accaaggtct ttttataaaa accaattccc
     2161 tcaccattaa tccccattcg cttaatctta agcggtattt tttgctttat tttgacattc
     2221 attcctgact aaatattact cctaatcgct taagccttgc tatcatctgc ttgccaacac
     2281 ctggaatatc aagaagctct tgagttgtcc aggccgaaaa atcctccaga gtatgaatcc
     2341 catactgatt aaacaaattg accttactta aaggaagatc aagctcctct agaaatgtta
     2401 gctcgccttc agccccttca aaaaattcct gaacataatg ctgcaggtaa tattgtgcag
     2461 tcatcaatag cggtaggata ttaaaaaagg caaggtaaat acttgataag ctgtttggct
     2521 cgtagctctc cagggcacca gcagctaaaa tatcatctat cggaaaggct ttctgtctga
     2581 caattgccac aaagtctggc accgtctcag caaggttagc caaaatatca tcagctagct
     2641 cttctctttc agctaatagc gctccaacca tcaaaggaac ctccatcaac agatctcctc
     2701 tatgataatc cttactgtca taaaaagcct ctgccatcgt aaaatcagac tttaacacat
     2761 aaagagctaa gatttcatac cttgtcccta agtgatcccc ttcatcgtat tgatgaattt
     2821 ctaagaggtg atgtaaagct ttttcataaa gaccattttg cttatacagc atcgccagct
     2881 caaatttttg agacaagtaa ggtctctctt caagattcac ccatcccata ggcttagaag
     2941 caagccaggc ctgatgctga cagtcttcat caaaggccaa atacttgatt aagtcatagg
     3001 ctctatctcc tgcaaagtgc tccaagtccg acaacaactg gttatccatg ctgtttaaaa
     3061 gagcctctaa gtcatcactg aaaaactctg tctcatgtcc aaagagcata tcatcttctg
     3121 catcagcttg gcgatagtgc tgtaagctaa caaccttatc tctatctttt ttatcttttt
     3181 ctgtcataat gccctttcaa tctattgacc atttatactc ttattttacc atttttgtta
     3241 taatgagggt atgaaaatca gtcaaattga aaagaaaaag catttatacc tcattaagct
     3301 agacaatggt gatagcctaa cggtcacaga agatacgatt gtcacattta tgctaagtaa
     3361 gcacatggtc atagacagcc aacaatggga ggacatcaaa agcttcgcac aattctcata
     3421 tggtaaaagc aaggccttag gttttattgc cttccaacaa aggagccaaa agcaagtcca
     3481 agattacctg ctaaagcatc agattagtcc tgatctcatt ccaagcatta ttgatagcct
     3541 aaaacaaggc aaatggattg atgatcagca atacgttgac acctatatac gccaaaatag
     3601 ccttactgga gacaagggac cattacttct caagcaaaag ctaatgctca agggaatagc
     3661 ctcacaactc attgagcctg tcctagcaca gactgatttt tcctctatag cacaaaaggc
     3721 tgctgaaaaa atctaccaga aatatcaaca caaattgcca agtaaggcct tgaccgataa
     3781 aatcatacaa ggacttctta acaagggctt ttcctatgac cttgccaaag gcattgtcag
     3841 tcaactaagc cttgagcagg atagtcagca catcgaagac ctgcttgatc aggaattcga
     3901 caagctatta cgaaaataca gtcgtcgcta tgatggctat cagttgaagc aaaagcttta
     3961 ccaagccctt taccgcaagg gctatgacag tgatgatatt accactaagc taaatgacta
     4021 tttctaattc taccaaggct gctgcaccga tttgacgcaa aagcttttag tcagcaacaa
     4081 agtagtccta ttatgatcct gtagctttga taatggttta gctagctcct caactgaaca
     4141 tcagatttct aaaaacttct ttaagcattt gtcagatcat attgtccaaa acagtgattt
     4201 attttctcaa ttatggtaaa ctatagagga taagtttaat tgtagaaagt tggtaaggca
     4261 tgaaattacc taaagaaggc gactttatta caattcaaag ttataagcat gatggtagat
     4321 tgcaccgaac ctggcgcgat actatggtac taaaaacaac tgaaaatgct ctgattggag
     4381 ttaatgatca cacacttgtt actgaaagcg acggcaggcg atgggtgaca cgagagcctg
     4441 cgattgttta ttttcataaa aaatactggt tcaatattat agcaatgatt cgagataatg
     4501 gtgtttccta ttattgcaac cttgcaagtc catacctgat ggacgcagaa gcgctcaagt
     4561 atattgacta tgatcttgat gtcaaagtct ttgcagatgg tgaaaagaga ttgcttgatg
     4621 tagacgaata tgaaatgcac aagcaagaaa tgcattattc acctaatctg gattttattt
     4681 taaaagagaa tgtcaagcta ttagtcgact ggatcaataa agaaaaagga ccattttcaa
     4741 aagcctatgt cagtatttgg tacaaacgtt atcttgaact gaagaatcgt tagtcgttgt
     4801 ctagcactcc accgagggtg ctttatttaa tcgctagtat agtatcacag ctgtaaactg
     4861 gactggcact tgcaatctat cagcatttgt tgtcaaattc atatcattaa ccactatagc
     4921 ttggcacaag cacagacagc ctataacacc aagtagcaat cagtatttat catcagctgc
     4981 ctagctagat caggcattca aatgacctca ttataacacc ataacaatag aaaggattga
     5041 caatggcatt tcaagcaaca aaaggacgat acgcaagctt tggcgttgca gtcagccttc
     5101 cacctgagct gattgatacc ttctgggaaa tcattgacca ttacctaaaa ggggtgtttc
     5161 ccctcaatac tgttctcacc ttcaggctaa ttaaaaataa aaaaaacctt tcttatgagt
     5221 acattgatca acaagctggg cttcggattg tttttgacta taacacacca tttaacgcct
     5281 tttaccccaa aacgctctat atcgtaaacc agcaaggaat tgaaacgatt ttattgcctc
     5341 acgagatgta ttgataagac ctcggacatc agctataaag tccttaccat tcagttgtag
     5401 ctcatcacat ctgctacaag caccaacatg agataatctt gtgtctttat cctagctctg
     5461 aatgctgtat agatattcag tcagccagat acatagcaat aaactaagct catgccggta
     5521 gaaatagtcc taacatgagc ttgacagttt tttcattctg taaatcattg ctaagcaaac
     5581 acatcaccta agccctattt cctattctgg gaaatggaaa tcttgataga acatcccaat
     5641 agtcccatca tattgagcta tatctatagg gtctgacatt ttgatatgtt atcatctcat
     5701 tttacgacaa tcactatagg ctttatgaca attggcatca ttgtcataac gattaaattc
     5761 tatatgacca aatggctagt aggaagctaa ttgctttgtg ttagcctcac ataggatctt
     5821 cacatacccc gtaatcttaa aagtagtttt aactgcacaa aacttataga acctaaaaat
     5881 caacaaacac actttaaagt acaaaaactt tgccctccct caaaaagctc tataatctct
     5941 gtagtcggta agcccactgt ggaaattata gtttttttaa ttgtacaaaa acaagcccat
     6001 atgacttatc atgaaatgca atcaaaccat cattagaaag actcatagga acaccttaag
     6061 cattactcag catttaaaaa acaatatcca accgttgact gttctaaaag ctcaccccca
     6121 catcgttatc aatcctaagc ttgattattc agttctctta tgccctcact acaaaggaaa
     6181 catgagcaaa caagacttcc aaaaagcctc taaaatccct atcttcgatt gccaaagctt
     6241 tccaacactg cttcaactca aaaaacactg ctttcagtgg aaagccagtt ctaaagtgag
     6301 ccttgctcaa actccttttg gttttaacat cacaaaaaag agcaccaatc tggtcctctt
     6361 tagacgttag tt
//
LOCUS       DARYXS010000100         6208 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.101, whole genome shotgun sequence.
ACCESSION   DARYXS010000100 DARYXS010000000
VERSION     DARYXS010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6208
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.101"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..6075
                     /locus_tag="TV193_001692"
     CDS             <1..6075
                     /locus_tag="TV193_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1513866.1"
                     /translation="WLNPVSKNNHQIPIVSFSDREELNEKLIVIDTNLNLGEDKSELL
                     HHSLDVINDKGSVIANQFIVKVDNQNRELTVYSEQNPNSHREFELSFDYLNGLGQIDG
                     DGNNLKLTKHKKETIDKKLKSYHSWKEDGEKRGIPGIAGSSITSPITDEMFWQMKEYE
                     EKLKEEERYAPDDKYLGGIPPINYKITKEDEILPPSERLKNNIEAIKVLKEIEERHSH
                     ATKEEQDILSRYVGWGGLSDVFDEEKGGQWKDAREFLKENLSPSEYDAARESTLTAFY
                     TPKIVIDSIYQAVLNMGFESGNILEPSMGTGRFIGNLPDSMKGSKFYGVELDSISGRI
                     ASRLYPNAKIQIKGFEETTFSNNLFDVAVGNVPFGEYKIVDREYEKNNFLIHDFFFAK
                     TLDKVRSGGVVAFISSSGTMDKKSEDIRRYISERAEFLGAIRLPNNTFKGEAGTEVTS
                     DIIFLKKRDRLVKLDEEWVKLGTDERGLTYNKYFVDNPDMVLGNMEEISSRFGTSLAC
                     VADENSTLKEQLDTAIKNIKGSYEKIELNNEFEVETIPADDSVKNYSYAVIDDKVYFR
                     ENSVMQKLNLNKNDEEKVRAYLGIEKALRQVIAYQKEDYSDTEIKEKQGELNRIYDEF
                     SKKYGILNSKANKKLFREDANYSLLSTLEKLDKEGNFIEKSDIFTKRTIKKAVAIEHT
                     DNLTEALILSISQKGKVNFEYMEKLTEKTRGEIIEGLKGEIFLNLDGFDPSDTTPFSS
                     AIDLGDFSRSYVTADEYLSGNIRDKIEVIDSYIKNVEHEFEQNEQLENIDADVLKQGS
                     ETLKKELSSLNYQRQKLLEVMPKELEASEITVRMGATWIPEKDYKSFMFHLLKTSASN
                     RWNIDIKYTNFTGEYRVEGKSIDKGNDLANFTYGTSRVSAYKLIEDTLNLRDTNVYDQ
                     VIDENGKKSSVLNQKETMLARSKQEIIKEEFKNWIFDDIDRRTRLVKEYNEKFNSIRL
                     REYDGSNLTFDGMNPEIELRPHQRDAIARGLFGGNTLLAHEVGAGKTFEMIGIAMESK
                     RLGMSNKSMFVVPNHIVEQFGREFNELYPAANILCATEKDFTPDKRKRFCSRIATGDY
                     DAVIIGHSQFEKIPISKQRQEYELQSQIDEIIDFIEEYKRNRDQKFTVKQLEKTKKGL
                     EAKLKKLNDDYRKDDVVTFEELGIDKLFVDEVHAFKNLYVFTKMRNVAGITTTDSQKS
                     SDMLMKCRYMDEITGNKGIVFATGTPVSNSMAELYTMQRYLQYDELKKMHLQHFDSWA
                     STFGETVTAIELNPEGNGYRSKTRFAKFYNLPELMNMVKQFMDIKTADVLNLPVPNAH
                     YETIKTKPTEEQKQILETFSERADKVRGKQVDSSVDNMLLITNDGKKMALDQRLINPL
                     LPDDPNSKVNTCVNNIFSIWDKYRDEKSTQLVFCDMSTPSSEFNIYDDIKEKLTKMGI
                     PKNETEFIHNAKNNKEKDKIFDKVRKGEIRVLLGSTQKMGAGTNAQNKLIATHDLDVP
                     WRPADLEQRKGRIVRQGNENDDVHIFRYITENTFDAYLFQTLETKQTYISQIMNSKTP
                     VRVAEDIDEATLNYAEIKALATGNPLIREKMDLDVEVSKLKMLESNFKSNLYKMEDKV
                     VKVYPKEIKSLKEKIENLKKDIEKVEPYREEKLEKYDQTTLENMGENEKQVGIKADKE
                     AISKFTSLTLNGKKYTDKKQAGEFLINKIKGIKKLDDFRSEEVKIGEYRNFDLFAYYD
                     RFSNQYKFNLKGEENHYGEFGTDEIGNITRMDNVLDRMPERLEQTLGKLKDTENQLET
                     AKLEIKKKFPQAELLKEKTLRLAEVNNLLDMGQKGDLKEEKNPLLEEVKEELIHFLNK
                     EYDEAHSIEDFDTMFPDLTDIGLAYTTTPDEKHEIQTSLDLINYKMNTYVDNTLIDSF
                     QYTYDPLNASDTKELIQIKTNIGFWDFNELVYVDEEKLKASLGLEIDDDGNFYDPLSK
                     DMDLDGVMDRYDADFRDSKVQSFGDLDKKEKASVMDRLGYFKEKIKKGGLQNENIDRK
                     IECKEEVR"
BASE COUNT         2464 a          802 c         1298 g         1644 t
ORIGIN      
        1 tggctaaatc ctgtatcaaa aaataatcat caaattccga ttgtaagttt ttctgacaga
       61 gaagagctaa atgaaaagct cattgttata gataccaatc ttaacttagg agaagacaag
      121 tcggaactgt tacatcatag tttagatgta ataaatgata aaggttctgt gattgccaat
      181 cagtttattg taaaagtcga taatcaaaac agggaactta cagtatatag tgaacaaaat
      241 cctaatagtc atagagaatt tgaactttct tttgattatc taaacgggct tgggcaaatt
      301 gacggagatg gaaataatct aaaacttaca aagcataaaa aagaaaccat tgataaaaaa
      361 ttgaaaagtt atcattcttg gaaagaagat ggggaaaaaa gaggaattcc gggaatagca
      421 ggttcttcta ttacttcacc tattactgat gaaatgtttt ggcagatgaa agaatatgaa
      481 gaaaaattaa aagaggagga aagatacgcc cctgatgata agtatttggg aggtattcct
      541 ccaatcaatt acaaaatcac aaaagaagat gaaatcttgc cgccgtccga aaggcttaaa
      601 aataacatag aagccatcaa ggtattaaaa gaaattgagg aaagacatag tcatgcaaca
      661 aaggaagaac aggatatttt gagtagatat gtcggctggg gtggactttc tgatgtcttt
      721 gatgaagaaa agggaggaca atggaaagat gcaagagaat tcttaaaaga aaatctatca
      781 ccgtctgagt acgatgcagc aagggaaagt acccttacag ccttttatac accgaagatt
      841 gtaatagaca gtatctatca agccgtatta aatatgggat ttgaaagtgg gaatatcttg
      901 gaaccaagta tgggaactgg cagatttata ggcaatcttc cagacagcat gaaaggcagt
      961 aaattttatg gtgtagaact tgacagtata agtggtagga tagcaagtag gctatatcct
     1021 aatgctaaaa tacagatcaa aggttttgaa gaaacgactt tttcaaataa tctgtttgat
     1081 gtagcggtgg gaaatgtacc gtttggagaa tataagatag ttgatcgtga gtatgagaaa
     1141 aacaattttc ttattcacga ttttttcttt gccaaaacct tggataaagt acgttccggt
     1201 ggagtagtag cctttataag ttcaagtgga actatggata aaaagagtga agatatcaga
     1261 agatatattt cagaaagagc agagttttta ggagcaatta gactacctaa taatactttt
     1321 aaaggcgagg cgggtacgga agtaacaagt gatattattt ttcttaaaaa gagagatcga
     1381 ctggtaaaac ttgatgaaga atgggtaaaa cttggcactg acgaaagagg actgacatat
     1441 aacaaatact ttgtagataa ccctgatatg gtacttggaa atatggaaga aatatcaagc
     1501 agatttggaa caagtcttgc ctgtgttgca gatgaaaata gtactctgaa agaacagctg
     1561 gataccgcca ttaaaaacat taaaggaagt tatgagaaga tagaattaaa taatgaattt
     1621 gaagtggaaa ccattccggc tgatgacagt gtgaaaaatt attcttatgc agtaattgat
     1681 gataaggtat attttagaga aaattccgtt atgcaaaaat tgaatttaaa taaaaatgat
     1741 gaggaaaaag taagggcata tcttggaata gaaaaagcat taagacaggt aattgcttat
     1801 caaaaagaag attattccga tacggaaatt aaggagaagc aaggggagtt aaatcgtatt
     1861 tatgatgagt tttccaagaa atacggaatt ttaaacagta aggcgaataa aaaactgttt
     1921 cgtgaagacg ctaattattc tttactgtcc actttggaaa agctggataa agaaggaaac
     1981 tttatagaaa aatccgatat ctttacaaaa agaacaataa aaaaagcagt agccatagag
     2041 cataccgaca atctgacaga agcacttatc ctatctattt ctcaaaaagg gaaagtcaat
     2101 ttcgagtata tggaaaagct cactgaaaaa acaagaggag aaatcattga aggattaaag
     2161 ggagaaatat tcttaaattt agatggattt gatccaagtg atacgactcc tttttcttca
     2221 gccatagact tgggagattt ttcaagatct tacgtaactg ctgatgaata tttatctgga
     2281 aatatcagag ataaaataga agtaatagat tcgtatataa agaatgtaga acatgaattt
     2341 gaacaaaatg aacagcttga aaatattgat gcagatgtac tgaaacaggg tagtgagact
     2401 ttaaaaaaag aactgtccag tttaaattac caaagacaaa agctgctaga agtaatgcca
     2461 aaggagcttg aggcaagtga aataaccgtt agaatgggag caacttggat acctgagaaa
     2521 gattataaga gctttatgtt ccatcttcta aaaacatcgg catctaatag atggaatatt
     2581 gatattaaat ataccaattt tacaggggag tacagagttg aaggtaaaag tatagataaa
     2641 ggaaacgacc ttgccaattt cacatacgga acaagcagag taagtgcata taaactgatt
     2701 gaagatacat taaaccttag agataccaat gtatatgatc aagtcattga tgaaaacgga
     2761 aagaaaagtt ctgtactaaa tcaaaaagaa acgatgcttg caagaagtaa acaggaaatt
     2821 atcaaagaag agtttaaaaa ttggattttc gatgatatag acagaagaac aaggcttgta
     2881 aaagaataca atgagaaatt caattcgata aggcttagag aatatgatgg aagtaattta
     2941 acttttgacg gaatgaatcc tgaaatagag cttagacctc atcaaagaga tgcgattgct
     3001 agaggacttt tcggtggaaa caccctactt gcacatgaag ttggagctgg aaagactttt
     3061 gagatgatag gaattgctat ggagtctaaa aggcttggaa tgagtaacaa gtcaatgttt
     3121 gtagttccaa accatattgt agaacagttt ggtagagagt ttaatgaact gtatccggca
     3181 gcaaatattc tttgtgcaac agaaaaagac tttacaccag ataaaagaaa aagattttgc
     3241 tcaaggattg caaccggtga ttatgatgcg gtaattatag ggcattcgca gtttgaaaag
     3301 attccaattt caaagcagcg acaggagtat gaacttcaaa gtcagattga tgaaattata
     3361 gattttatcg aagaatataa aaggaataga gatcagaaat tcaccgttaa gcagcttgaa
     3421 aaaacgaaaa aaggactgga ggcaaaacta aagaaattaa atgatgatta tagaaaagat
     3481 gatgtcgtaa cctttgaaga attggggata gacaagctat ttgtagacga agttcatgct
     3541 tttaaaaatt tgtacgtttt tacaaaaatg cgtaatgtag caggaattac aaccacagat
     3601 tctcaaaaat caagtgatat gctgatgaag tgcagatata tggatgaaat taccggtaat
     3661 aagggtattg tatttgcgac aggaacccct gtgagcaatt ctatggcaga gctttatacc
     3721 atgcagcgtt atctccaata tgacgaactt aaaaaaatgc acttgcaaca ctttgattct
     3781 tgggcatcta cttttggaga aactgttaca gcaattgaac ttaatcctga agggaacgga
     3841 tatcgaagca agacaagatt tgcaaaattt tataaccttc cggaactgat gaatatggtc
     3901 aagcagttta tggatataaa gactgctgat gtattaaatc ttcccgttcc aaatgctcat
     3961 tatgaaacga taaaaaccaa accgacagaa gaacaaaaac aaatccttga aactttttct
     4021 gagagagctg ataaggttag aggaaaacag gtggattcct ctgtcgataa tatgcttctg
     4081 attactaatg acggaaagaa aatggcactt gaccaaaggt taattaatcc attacttcct
     4141 gatgatccga acagtaaagt aaatacctgt gtaaataata tattcagtat ttgggataaa
     4201 tatagggatg agaagtccac acaattagtt ttttgtgata tgtcaacacc atcaagtgaa
     4261 tttaatattt atgatgatat aaaggagaag ctgacaaaaa tggggattcc taaaaatgaa
     4321 acagagttta ttcataacgc aaagaacaac aaagaaaaag ataagatttt cgataaggta
     4381 cgaaagggtg aaattcgtgt gcttctcggt tcaacgcaga aaatgggagc agggacaaat
     4441 gctcaaaata aattgattgc tacccatgat ctcgatgtac cctggaggcc tgcggatttg
     4501 gagcagagaa aaggaagaat tgtaaggcaa ggtaatgaaa atgatgatgt tcatatcttt
     4561 cgttatatta cggaaaatac ctttgatgcg tatcttttcc aaacacttga aaccaagcaa
     4621 acttatatat ctcaaataat gaattcaaag acacctgtaa gagtagcgga ggatattgat
     4681 gaagctacat taaattatgc ggagattaaa gcacttgcaa caggaaatcc gcttattcgt
     4741 gaaaaaatgg accttgatgt tgaggtaagt aaacttaaaa tgctggagtc caattttaaa
     4801 tccaacctat ataaaatgga agataaggtt gtaaaagtat atccaaaaga aattaaaagt
     4861 ctaaaagaaa aaatagaaaa tttgaaaaag gatatagaaa aagtggaacc gtatagggag
     4921 gaaaaactag aaaaatatga tcagactact ttagaaaata tgggtgaaaa tgaaaaacaa
     4981 gtggggataa aagcagataa agaagcaata tcaaaattca catctttaac tttaaatggg
     5041 aaaaaatata ccgataaaaa gcaagccgga gagttcttaa taaacaagat aaaaggaata
     5101 aaaaaattag atgattttcg ttctgaggaa gtaaaaatcg gagaatatag aaatttcgat
     5161 ttgttcgcat attatgacag gttctccaat cagtataaat tcaatctgaa gggagaagaa
     5221 aatcattatg gggagtttgg aacggatgaa atcggaaata tcacccgaat ggataatgta
     5281 cttgatagga tgcctgagag attggagcag acacttggaa aacttaaaga taccgagaat
     5341 caacttgaaa cggcgaagct tgaaataaaa aagaaatttc cacaggcaga gcttttaaaa
     5401 gaaaagacgt taagacttgc tgaggtaaat aatttgcttg atatgggaca aaaaggagat
     5461 ttaaaagagg agaaaaatcc acttttggaa gaagtgaagg aagaactgat tcattttcta
     5521 aataaagaat atgatgaagc acacagtata gaagatttcg atacaatgtt tcctgacttg
     5581 acagatatag gtttggcata tacgactaca ccggatgaaa agcatgagat acagacaagt
     5641 cttgatttaa tcaattacaa gatgaacact tatgtagaca atactttaat tgacagtttt
     5701 cagtatactt acgatccact taatgcaagt gatacgaagg aacttataca aatcaaaacg
     5761 aacataggtt tttgggattt taatgagctg gtatatgtgg atgaagaaaa gttaaaagca
     5821 tcacttggac ttgaaattga tgacgatggt aatttctatg atccgctttc aaaggatatg
     5881 gatttagatg gagtaatgga caggtatgat gcagacttta gagatagtaa agtacaaagt
     5941 tttggagatt tggataaaaa agaaaaagca tccgtaatgg ataggcttgg atacttcaaa
     6001 gaaaagataa agaaaggagg cctacaaaat gaaaatattg atagaaagat agagtgtaag
     6061 gaggaggtta gatagttgga atatcacaaa aatattagag caacggatag agaaatgcag
     6121 aaactttttg aaaatgagga gtataactat tccgtaagat attttgaaaa aatagaagaa
     6181 aacttattta aaacgataat tcgcacac
//
LOCUS       DARYXS010000101         6106 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.102, whole genome shotgun sequence.
ACCESSION   DARYXS010000101 DARYXS010000000
VERSION     DARYXS010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6106
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.102"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            71..1321
                     /locus_tag="TV193_001693"
     CDS             71..1321
                     /locus_tag="TV193_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEL1513867.1"
                     /translation="MKELKCPHCHTLFTVNESDYSQILAQVRGQEFDKELAQRLESEM
                     KLQEARANNRFQEVLTKKEQAIQSLTNRLERIEQEQAYLRQQELAQKDKELLELHNQL
                     DKLELEQQSRLQSALTVVEKERDHLKNQLVLQEKESELSLASVRSDYEVQLKAVNEQV
                     EFYKNFKAQQSTKAIGESLELYAETEFNKVRSYAFPNASFTKDNQVSHRGSKGDYIYR
                     ELDNNGVEILSIMFEMKNEVDTTKTKHKNSDFFKELDKDRREKNCEYAVLVTMLEADN
                     DYYNAGIVDVSHDYDKMYVVRPQLFIHLIGLLRNAALNSLKYKQELALVREQHIDITH
                     FEEDLEHFKHAFAKNYQSASNNFKKAVDEIDKSIKRMEEVKRFLTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMRDKFQAIKP"
     gene            1430..2311
                     /gene="truB"
                     /locus_tag="TV193_001694"
     CDS             1430..2311
                     /gene="truB"
                     /locus_tag="TV193_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEL1513868.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKTYEGEVTLGYSTTTEDASGEIVDQTVVPLSLTEAMVD
                     EAMTQFIGQMTQIPPMYSAVKVNGRKLYDYARAGEAVERPKRQVTIDQFERTSPLTFA
                     GGLCRFSFRVSCSKGTYIRTLAVDLGRMLGYASHMSWLVRTASSGLSLDQSYTLSEIA
                     ELLDKKDMSFLLPIEYGVSDLARVVVNDWELRELSFGRKIALSCEENLLAAFYQDSLI
                     AILEKQEGLYKPRKVFI"
     gene            2325..3257
                     /locus_tag="TV193_001695"
     CDS             2325..3257
                     /locus_tag="TV193_001695"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEL1513869.1"
                     /translation="MDIQHIKSYQEIDESADTVLVLGYFDGLHRGHKALFDKAKEISR
                     QESLKIVTLTFHESPQLAFTRFSPDFLRHITYPEKRYEKFAEYGVDKLYLLDFTTSFS
                     KLSSDDFIDHYIGRLRVRHIVVGFDYHFGCDHADSHYLAKRIKGTVYSISEVKEDQIK
                     ISSTRIRSLITAGDVAKANQLLGYELSTRGMVVHGDARGRTIGFPTANLAPIDRTYLP
                     ADGVYVTDVLVRGKRYRSMTSIGKNITFGGKELRLEANIFDFNEDIYGETLEIIWLDR
                     IREMNKFSDVSTFISQLKQDKEAAINWKKDSQGY"
     gene            3300..3704
                     /locus_tag="TV193_001696"
     CDS             3300..3704
                     /locus_tag="TV193_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEL1513870.1"
                     /translation="MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLA
                     ILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLIDLIAKNPSLLRRPIIMDSKRMQ
                     IGFNEDEIRAFLPRDYRKQELRQATIKAEIEG"
     gene            3706..3984
                     /locus_tag="TV193_001697"
     CDS             3706..3984
                     /locus_tag="TV193_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEL1513871.1"
                     /translation="MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVGAEELLKS
                     YAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR"
     gene            3974..4750
                     /locus_tag="TV193_001698"
     CDS             3974..4750
                     /locus_tag="TV193_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEL1513872.1"
                     /translation="MEDKYAFAKTIIKEAGLLIKDRMKDSLAIEIKTQHDDLVTNVDQ
                     ETQDFLIAKIKQAYPSDHMIAEEGGICHAITDGKVWVLDPIDGTVNFIVQKANFAIMM
                     AYYENGVGKFSLIYDVMADQLFSGGGDFAVTLNDQVLASYQDKPLDRSLIGCNAGMLS
                     RNDYNLHQLIDQTLGVRVYGGAGICMTKVLRQQLMAYFSYIQPWDYAAAAIMGESLGY
                     VLLTLEGKQPDFQSRQKVMFVPKSKLATIQSLLKTNENTQ"
     gene            4767..6074
                     /locus_tag="TV193_001699"
     CDS             4767..6074
                     /locus_tag="TV193_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEL1513873.1"
                     /translation="MQLPNDFIEKYQQLLGSEAKAFFESFDQPAISAYRINPLKHQSV
                     CLDPPIPDTPWGYYGRVSGKSPNHVSGVVYSQEPAAQMVAQVASPAKGTRVLDLAAAP
                     GGKSTQLLAYLENTGLLVSNEISTKRSKALVENIERFGARNVIVTNESADRLAAVFPE
                     YFDTIVFDGPCSGEGMFRKDPNAVSYWHKDYPAACASLQRSILAEAIPMLKPGGQLIY
                     STCTWSPEENEEVVRWLLESYDFLELEHIPKINGMAEGIGMPQAARMYPHRFKGEGQF
                     VAKLKDTRSTISSSSYKSPRSNLTQEQLRLWQDFEKNHLNITLSGLLQVFGDRLYLLP
                     DGLPCLRSLKIARNGLELGTFKKKRFEPSYALGLALRPEEVSLSVEINEEDFVTYASG
                     NTITLPESYATDWYQLVINGNGLGFAKIVGRTLKNSFPKGLRF"
BASE COUNT         1863 a         1121 c         1428 g         1694 t
ORIGIN      
        1 tctggaaaaa tcattttcta ggcttttttt gctataatgg cagtgagata attgcaagaa
       61 tggagaaatc atgaaagaac taaaatgtcc tcattgccat accttattta cggtcaatga
      121 gtctgactat agtcagattt tagcacaggt acgaggtcaa gagtttgaca aggagttggc
      181 acagcgctta gaaagtgaga tgaagctgca agaagcaagg gccaataacc gcttccaaga
      241 ggtgcttact aaaaaggagc aggctattca aagcctgacc aaccgcttgg agcgtattga
      301 gcaggaacag gcctatttga ggcaacagga gctagcccaa aaggataaag agctcctaga
      361 gcttcacaat cagctagata agctagagct tgagcagcaa tcaaggctcc agtctgccct
      421 tacagttgtt gaaaaggaac gtgatcacct aaaaaatcag ctcgtgctgc aggaaaaaga
      481 aagcgaactt tctctagcct ctgtgcgcag tgattatgag gtgcagttaa aggctgtcaa
      541 tgagcaggtt gagttttaca agaattttaa agcgcagcag tcaactaaag ctattggaga
      601 gagcttagag ctgtatgccg aaaccgagtt taacaaggtt cgcagctatg cctttccaaa
      661 tgccagtttt accaaggaca atcaagtgtc tcatcgaggc tcaaagggtg attatattta
      721 ccgagagcta gacaataatg gtgttgaaat tctctcaatc atgtttgaaa tgaaaaatga
      781 ggttgacacg accaagacca agcataaaaa tagtgatttc tttaaggaat tagataagga
      841 tcgccgggaa aagaattgtg aatatgctgt tcttgttacc atgcttgaag cagacaatga
      901 ttattacaat gcaggaattg ttgatgtcag tcatgactat gacaaaatgt atgtggttcg
      961 gcctcagctc tttattcatc tcatcggatt gctgcgtaac gctgctctta atagcttaaa
     1021 atataagcaa gaactggcgc ttgtcaggga gcagcacatt gatattacac attttgagga
     1081 ggacctagag cattttaagc atgcttttgc taaaaactac cagtctgcaa gcaataactt
     1141 taaaaaagcc gttgatgaaa ttgataagtc catcaagcgt atggaggagg tcaagcgctt
     1201 tctaacaact agcgaaaatc agctgcgttt agccaataac aagctagatg atgtctctgt
     1261 caaaaaacta accagaaata atccaaccat gcgcgataag tttcaagcaa tcaagcccta
     1321 ggattatctc agtcaggctt attgatagag gctttgttgc ttgtcaaaag ccttgtgaaa
     1381 tggttataat agataggcta atgatcaaaa caataaacga aagtaacaca tgataaacgg
     1441 aataatcaat ttaaaaaaag aagcaggcat gacatcacat gacgctgttt ttaagcttag
     1501 aaagctatta caagaaaaaa agattgggca tggagggacg cttgatcctg acgtggtcgg
     1561 tgttttgcct atagcagtgg ggaaggcaac gcgagttatt gaatacatga cagaagcagg
     1621 taaaacctat gagggagagg ttactcttgg ctattcaacg acaacagagg atgctagtgg
     1681 agagattgtt gaccaaacag tagtgccctt gagtttgact gaagcgatgg ttgatgaggc
     1741 aatgacacaa tttattggtc aaatgactca gattccaccg atgtattctg cggttaaggt
     1801 taatgggcgc aagctttatg attatgcacg agctggtgaa gcagtcgagc gccctaaaag
     1861 acaggtaacg attgaccagt ttgagcggac aagtcccttg acctttgcag gtggtctttg
     1921 ccgatttagc tttagggtga gctgtagcaa ggggacttat attaggacct tggcggttga
     1981 tctaggaaga atgcttggct atgcaagtca tatgtcttgg ctggttcgga cagcttcttc
     2041 gggtttaagt ttggatcagt cctatacctt gtcagagatt gctgagctgc tggataaaaa
     2101 ggacatgagc tttttattgc ctattgaata tggtgttagt gatttagcca gagtagtcgt
     2161 taatgactgg gagctgagag agctttcctt tggtagaaaa atcgctctat catgtgagga
     2221 aaatctgtta gcggcttttt atcaggacag cttgatcgct attttagaaa agcaagaagg
     2281 gctttacaag ccaagaaagg tttttattta gagaagattg atatatggat atacaacaca
     2341 ttaaaagcta tcaggagatt gatgaatcag ctgataccgt tttagtctta ggctactttg
     2401 atggtctgca ccgaggtcac aaggctctat ttgataaggc aaaggaaata tcacgtcagg
     2461 aaagcctaaa aatagtcacc ttgaccttcc atgagtcccc tcagctggcc tttacacgct
     2521 tttctcctga ttttttacga cacattacct atccagaaaa aaggtatgaa aaatttgctg
     2581 agtatggtgt tgataagctt tatttgcttg attttaccac gtcattttca aaactatcct
     2641 ctgatgattt cattgaccac tatattgggc gtttaagggt aaggcatatc gttgtaggct
     2701 ttgattatca ctttgggtgt gatcacgcag atagtcatta cttagctaaa cggataaaag
     2761 gaaccgttta tagcatttca gaggtcaaag aagaccagat caaaatctca tcaacacgta
     2821 tcagaagtct gattacagca ggagatgtcg ctaaggctaa tcagctgctt ggctatgagc
     2881 tttcaacaag aggaatggtt gtgcatggtg atgcgcgtgg gcgaaccatt ggttttccga
     2941 ctgccaatct tgcacctatt gataggacct atctgccagc tgatggtgtt tacgtgacag
     3001 atgtgctggt tagaggaaag cgctatcggt ctatgacgag tatcggcaag aacattacct
     3061 ttggtggtaa agagctgcga ttagaggcaa atatttttga ttttaatgag gacatttatg
     3121 gagaaactct tgaaattatt tggctagata ggattcgtga gatgaataaa tttagtgatg
     3181 ttagcacctt tatcagccaa ctaaagcagg ataaagaagc tgccataaat tggaaaaaag
     3241 atagccaagg ctattaaatt tttgtataat aaggtaagca caattaacag aggaaaagta
     3301 tgattacctt atttctatca ccaagctgta ctagctgccg taaggccaga gcctggctca
     3361 ccaagcatga cgttgacttt caagagcata atattattac cagcccactt agtcgtgagg
     3421 agctgttagc gatcctatcc tttactgaaa atggaacaga ggatattatt tcaacacgat
     3481 caaaggtttt tcaaaaattg gatattgata ttgatgagct gtctatcatg gatttgattg
     3541 atttgatcgc aaagaaccct agccttcttc gtaggccaat cattatggat agtaagcgca
     3601 tgcaaattgg ctttaatgaa gatgagatta gggcattttt gccaagggat tatcgtaagc
     3661 aagagctgcg ccaagcaacc ataaaggcag aaatcgaggg ataacatgtc agatcattat
     3721 cattacccac ttgatgtaag ctggagcact gaagagataa catcagtgct tcatttttta
     3781 aatcaggtag agttagccta tgaggctaag gtaggagcag aggagctact caaaagctat
     3841 gctgcctaca aggagattgt aagaagcaaa tcacaggaaa agcagattga ccgcgaattc
     3901 caacaagcca gtggctattc aacctatcaa gctgtcaaaa aagccagaga aattgagaaa
     3961 ggattctttt cccttggaag ataaatacgc atttgctaaa acgatcatca aagaggctgg
     4021 ccttctgatt aaggatagaa tgaaagatag cttagccatt gaaatcaaga cgcagcatga
     4081 tgatttagtg accaatgtag atcaagagac gcaggatttc ttaattgcta aaatcaaaca
     4141 ggcctatcct agtgaccata tgattgctga ggagggcggt atctgtcatg ctattacaga
     4201 tggcaaggtt tgggtgctgg atcctattga tggtacggtg aattttattg tacagaaagc
     4261 caattttgcg atcatgatgg cttattatga gaatggcgtc ggaaaattta gtctcattta
     4321 tgatgtcatg gcagatcagc ttttttcagg tggaggagat tttgctgtta ctttaaatga
     4381 tcaagtccta gcatcttatc aggataagcc gcttgatcgt agcttaattg gctgcaatgc
     4441 aggtatgctt tcaaggaacg attacaacct gcaccagttg attgatcaaa ccctaggagt
     4501 gagggtttat ggcggtgcag gcatttgcat gactaaggtg ttaaggcagc agctaatggc
     4561 ttatttctct tatattcaac cttgggatta tgcagcggca gccattatgg gcgaaagcct
     4621 tggctatgtc ctgttgacct tggagggaaa gcagccagac tttcagtcta gacagaaggt
     4681 gatgtttgtt cccaagtcta aactagccac cattcaatct ctgctgaaaa caaacgagaa
     4741 tacccaataa gattaaaatg aaaagcatgc aattaccaaa cgattttatt gaaaaatacc
     4801 aacagctgct aggttcagaa gcaaaagctt tttttgagag ctttgatcag cctgccatca
     4861 gtgcctacag gataaatccc ttaaagcacc aatcggtctg ccttgatcct cctattcctg
     4921 atacaccatg gggttactac ggcagggtat caggaaagtc tcctaaccac gtgtcaggtg
     4981 tggtgtattc ccaagagcct gctgctcaaa tggttgctca ggtggcctca cctgccaagg
     5041 gaactagagt gttggatttg gcagcagcgc caggtggcaa gtcaactcag ttacttgcct
     5101 atctagagaa tacaggactt ttagtgagta atgagatttc gaccaaacgc agcaaggcct
     5161 tagttgaaaa tatagagcgc tttggtgcta gaaatgttat tgtgacaaat gagtcagctg
     5221 acagactggc tgctgttttt ccagaatatt ttgacactat tgtctttgac gggccttgct
     5281 ctggtgaggg catgtttcgc aaggatccaa atgctgttag ctattggcac aaggattacc
     5341 cagcagcatg tgctagcctg caaagatcca ttttagcaga ggcgatacct atgctaaagc
     5401 caggtggtca gctgatttat tcgacctgca cctggtcgcc tgaagaaaat gaagaggttg
     5461 ttcgctggct actagaaagt tatgattttc ttgagctgga gcatatccct aagatcaatg
     5521 gtatggcaga ggggatcggt atgccacagg cagctagaat gtaccctcat cgctttaaag
     5581 gagagggaca gtttgttgct aagttaaagg atactagatc aacgatttcc tcttcaagct
     5641 acaaatctcc aaggtctaac ctcactcaag agcagctgag gctgtggcag gattttgaaa
     5701 aaaatcattt gaacataacc ttgtctggcc tattacaggt ctttggtgat cgtttgtact
     5761 tgttaccaga tggcttaccc tgtcttcgat cgcttaaaat agcaagaaat ggtctggaat
     5821 taggcacttt taagaaaaaa cgctttgagc cttcctatgc tctgggcttg gcattaagac
     5881 ctgaagaggt cagcttatct gttgagatta acgaagagga ctttgtcaca tacgcctcag
     5941 gaaataccat taccttacca gaatcttatg ctacagattg gtatcagctg gtcattaacg
     6001 gaaatggtct gggctttgct aaaatagttg gtcgcaccct taaaaatagc ttccctaagg
     6061 gcttacgttt ttaaggaatg gcataccatt aaatttttat aaattt
//
LOCUS       DARYXS010000102         5973 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.103, whole genome shotgun sequence.
ACCESSION   DARYXS010000102 DARYXS010000000
VERSION     DARYXS010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5973
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.103"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            262..1089
                     /locus_tag="TV193_001700"
     CDS             262..1089
                     /locus_tag="TV193_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEL1513874.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHLESLLGYFPNHLNVWRSSVEPARKGYAGTMFLYKKELNPIVTFPDI
                     GAPTTMDAEGRIITLEFNDFFVTQVYTPNAGDGLRRLEERQLWDQKYADYLAQLDAQK
                     PVLATGDYNVAHKEIDLANPASNHRSPGFTDEERLGFTNLLNRGFTDTFRFIHGDIPN
                     VYSWWAQRSKTSKLNNTGWRIDYWLTSNRLIDKVSRSEMISSGERQDHTPILLEIDL"
     gene            complement(1165..1518)
                     /locus_tag="TV193_001701"
     CDS             complement(1165..1518)
                     /locus_tag="TV193_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEL1513875.1"
                     /translation="MITIYQYPKCSTCQKALAELKTLVSEVDIIDIKANPPKAEQLKQ
                     WLEHSDYSLKSFFNTSGMRYRELGLKDKVNSLSVEEAAELLATDGMLIKRPILLQDNQ
                     VLQVGYRTAYKDLGL"
     gene            complement(1522..2034)
                     /locus_tag="TV193_001702"
     CDS             complement(1522..2034)
                     /locus_tag="TV193_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEL1513876.1"
                     /translation="MWGGQILPLYECVYQSPLGKISLVATDVALIGAWFEGQRYFQAG
                     IKVQPIWQEQHALLKRACLWLDAYFERKPYPMLDCLSPQGTDFQRAVWRELQTIRWGE
                     TLSYGELAKRLQCRSAQAVGGAIGRNPLSIFIPCHRVLAADGRLIGYAGGLEKKAWLL
                     RHEQISVNKE"
     gene            complement(2491..3045)
                     /locus_tag="TV193_001703"
     CDS             complement(2491..3045)
                     /locus_tag="TV193_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1513877.1"
                     /translation="MEIRLAFPNELSQIMTVINSAKSALAQSGSSQWQKADGYPAYQD
                     IAADVLQGQGYVALLEGQIVAYAAVIDGQEDAYDKIYDGRWQHNHHRYVTFHRVAVLS
                     DRTGQGIAQTFLQGLIEGQHGPDFRIDTHEHNQVMRHIIEKLGFVYCGKVPIDGERLA
                     YQKIKKSHERAAYQEISEDSRYSY"
     gene            3256..3885
                     /locus_tag="TV193_001704"
     CDS             3256..3885
                     /locus_tag="TV193_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEL1513878.1"
                     /translation="MIKEFCAENLTMLNQLTSQSVNRVELCDNLAVGGTTPSYGVIKE
                     ACDLLHDKQISVATMIRPRGGDFVYNDLELRAMEADILKAIEAGTDALVIGLLTKDNQ
                     LDTDAIEQLLPATQGLPLVFHMAFDLIARDQQIASLEQLIDYGFVRILLHGSSDTRSI
                     YENIDHIKQLVKAAQHRIEIMIGGGVTADNCQELSQLTGTAIVHGTKII"
     gene            4344..5429
                     /locus_tag="TV193_001705"
     CDS             4344..5429
                     /locus_tag="TV193_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513879.1"
                     /translation="MTTRYFYKLLLTMLTLALGGFSLSACHSKISKPYQVAIFDKDHV
                     RTFMEKADSLVPVETISRTQHKLFERESFKQAKQGYFAKTREGNDLKVLLTHIDQASL
                     EEKVLHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDRHLKKQAHKSILNQDTINAS
                     NQFLVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRT
                     LYITQAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIEN
                     DQHYNPDFAWTIYQLDTGEERTIRFEELAGQETSSPYFMMTSSNYYFLFPKRLYRYDC
                     SNHQMTCINLDQYGVTHAHALIAKPTP"
     gene            5615..>5973
                     /locus_tag="TV193_001706"
     CDS             5615..>5973
                     /locus_tag="TV193_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TQXA domain-containing protein"
                     /protein_id="HEL1513880.1"
                     /translation="MYESPEKIPYQLPLYDKYEGNNSLFRDNASPNFRADVKDITATL
                     VAVLSNGYPTGKSSFCKDYCPDEIRARQLTQLAIWYFTDGISEETLKSNYSLNDLEFQ
                     GLKYLIQAGKTAGTSNNR"
BASE COUNT         1808 a         1443 c         1149 g         1573 t
ORIGIN      
        1 ttttaatcac aaaagcaata agactagaag ctctcagttt atgtcatttt ttaatcattc
       61 aactcactga aatgaggcct ctcagaacct gtctcatcaa cagataaggc taaactcagc
      121 cgctagactt caaaaatgtc acaccatttt tagacattac ctgtcctcat acctataaca
      181 gaaccaagct tccacagtcg ccttggcctt atttttttgt tacaatatag gttaagatta
      241 tcatttagaa agcgaagaaa aatgaaactc atctcatgga acattgattc tttaaatgct
      301 gcgctcactg gtgaatctcc tagagccctc ttatcacgcg ctgtacttga tactctcgtg
      361 gcacaggacg ctgatattat tgcaattcaa gagacaaagc tatctgccaa aggccctacc
      421 aaaaagcacc ttgagagctt gcttggctac tttcctaatc atctcaatgt ttggcgttca
      481 tctgttgagc ccgccagaaa aggctatgcc ggaaccatgt tcctctataa aaaagagctc
      541 aatcccattg tcacattccc agatatcgga gctcctacca ctatggacgc tgaagggcgt
      601 atcatcaccc tagaatttaa cgatttcttt gtcacacagg tctacacccc aaatgccggt
      661 gatgggctta gacgcttgga agagcgccag ctctgggacc aaaaatatgc cgactaccta
      721 gcccagctcg atgcccaaaa gcctgttttg gctactggtg attacaacgt tgcccacaag
      781 gaaatcgacc tggctaaccc agctagcaac caccgctctc cgggctttac agatgaggag
      841 cggcttggct ttacgaacct gcttaaccga gggtttacag atacctttcg ctttattcat
      901 ggcgatattc caaacgttta tagctggtgg gcacagcgca gcaagaccag taaattgaac
      961 aataccggct ggagaattga ttactggctc acgtcaaatc ggttgattga taaggttagt
     1021 cgctcagaga tgatttcctc aggagaacgt caggatcaca caccgatttt attagaaatt
     1081 gatctataga ctagaagcat tcggacaaat caacccagac attaaaaaaa aatggctctg
     1141 caagagaacc gtttttttaa tcgcttaaag acctagatcc ttataggctg ttcgataccc
     1201 tacctgcaag acctgattat cctgtaagag gatcggccgc ttaatcagca tgccatctgt
     1261 tgccaaaagc tccgctgcct cctcaacgct cagtgaatta accttatctt taagcccaag
     1321 ctcacgataa cgcataccac tggtattgaa aaagcttttg aggctataat ctgaatgctc
     1381 tagccattgt ttcagctgct cagctttagg gggattggcc ttaatatcaa tgatatcaac
     1441 ctcagaaacc agggtcttta gctcagcaag ggctttttga caggtactac actttgggta
     1501 ttggtaaatg gtaatcatta gctactcctt attaacacta atttgctcgt gcctgagcaa
     1561 ccaggccttc ttttcaagtc ctccagcata gccaatcaag cgaccatcag cagccagtac
     1621 acgatgacag ggaataaaaa tacttaaagg attacgtcct atggcaccac caacagcctg
     1681 agccgaacga cactgcaggc gcttggcaag ctcaccatag ctcaaggtct ctccccatct
     1741 tatcgtctgc aattctcgcc agacagctcg ctgaaaatca gtaccctgtg gagataagca
     1801 atcaagcatg ggatagggct tcctctcaaa gtaagcgtca agccacaaac aggctctttt
     1861 taacagggca tgctgctcct gccagatggg ctgcacttta atcccagcct gaaaatacct
     1921 ttgaccttca aaccaggctc ctatcaaagc aacatcagtc gcaaccaagg atatttttcc
     1981 taagggcgat tgatacacac actcgtacaa tggcaagatc tgacctcccc acataatagc
     2041 ttattccctt gactatttat tataagaaaa agcctagcta aaggcaagaa ggagccctct
     2101 gacaccacaa caaacgcatg aaaaaacaat agcggctctt tcaatgctgc catacaatcg
     2161 ttagtgtcaa aagtcgctta ctatacagct gccccccttg aaaaacgaag ctggaaagac
     2221 acaacatgct aaagctgttt cacgcgctgg tgcctgatta gatgttcttc taattaaagg
     2281 ccaatgttct gattaaaaag tcatttcatg cgctgatacc tactcaaata aaaacacata
     2341 gcgtggggct agaccaatcc ctcacaagtc atcaatagtt cgtctatgag ctacacttta
     2401 tcacattggg ataggcagac atatttgccg gctcagttgt acttgcctga tagctaacca
     2461 aaagcccgat aagctttttc cgatcctata tcaatagctg tagcggctat cctcgctaat
     2521 ctcctgataa gcggctcttt catggctttt cttaattttt tgataggcta agcgctcgcc
     2581 atcaattggt accttgccac agtaaacaaa gcctaacttt tcaatgatat gccgcatgac
     2641 ctgattatgc tcatgagtat ctatccgaaa atctggtcca tgctgcccct caatgagccc
     2701 ttgcaaaaag gtctgagcaa ttccctgacc agtcctatca ctcagcaccg ccacacgatg
     2761 aaaggtcaca taacggtggt gattatgctg ccacctgcca tcataaatct tgtcgtaggc
     2821 gtcctcttgg ccatcaataa cagccgcata agcaacaatc tgcccctcaa gcaaagccac
     2881 atagccctgc ccttgcaaca catcagcagc aatatcctga taagcaggat acccatctgc
     2941 tttctgccat tggctggagc ctgattgggc taaggcagac ttagctgaat tgatcactgt
     3001 catgatctga ctaagctcat taggaaaagc aagtctaatc tccatcgttc acactcacaa
     3061 tctattctga tttgatgatg ctatgctacc gcaaaaagcc ttacaccttg tcactctgct
     3121 agggacacct catagcggta tgcctgcttc tcatctcagc tgagtatagc acaatagtca
     3181 tcatttgaca aaaagcctct tcaaggattg ccagcaatca tgctataata aagtaaatca
     3241 caaaggagaa ccattatgat taaagaattt tgtgctgaaa acctaaccat gctaaaccaa
     3301 ttgaccagcc agtcggtcaa tcgtgttgag ctctgcgaca atcttgcagt cggtggcacc
     3361 acaccctctt atggtgtcat caaggaagcc tgcgacctcc tacatgacaa gcagattagt
     3421 gtcgcaacaa tgatccgccc aagaggaggt gattttgtct ataacgacct tgaattgcgt
     3481 gctatggaag cagatatctt aaaggctatc gaagcaggaa ctgatgcctt ggtcataggc
     3541 ttactcacta aggacaacca gcttgacacc gatgctatcg aacagctcct accagctaca
     3601 caaggactcc ctctggtttt tcacatggcc tttgacctga ttgctcgcga ccaacaaatc
     3661 gcaagcctag agcagctcat tgactatggc tttgtacgaa tcctgcttca tggctcaagc
     3721 gataccagat ccatctatga aaacattgac catatcaagc agttagtcaa ggctgctcag
     3781 caccgaatcg aaatcatgat tggtggaggt gtcacagctg ataactgcca agagctaagt
     3841 caactaacag gaacagctat tgtgcatggc acaaaaatca tctaactatc agctcaaata
     3901 aaggaaaagt cactccctac aaggaggtaa ataatagcag cccttctcgt tgaaggccat
     3961 acctgagccc ttagactagg ctcctagcaa actaatagta taggaccttc gctgccttta
     4021 catcaaaaag gctgccgtcc agaaaaagag aaagccacac attgatagaa aaccatagct
     4081 ggctctacta ctatcagtat ctatcatcag cttctgagct gcctaaaagt ttcggtgatc
     4141 attaacaagt acagactatt tgtttctaaa ttagatcata aaacagacaa ttataggaag
     4201 cgacaagtga atcattattc attttttatt gattactatg atactataag taaggatagc
     4261 gctttctttt tgtctttgct ttgcctgact attaggctct agatttattt tttaccatac
     4321 taatataaga atcggaataa ataatgacaa caaggtattt ttataagcta ttgctaacga
     4381 tgttgacact agcattagga ggattttccc tatctgcttg ccactccaag attagtaagc
     4441 cctatcaagt cgctattttt gacaaggatc atgttaggac ctttatggaa aaagctgaca
     4501 gtctggtgcc tgttgagacc atctctcgaa cacagcacaa gctatttgag cgagaaagct
     4561 ttaagcaggc caagcaaggg tattttgcaa agacaagaga aggaaatgac ctcaaggttc
     4621 tgttaactca cattgatcaa gcaagcctag aagaaaaagt ccttcatgct gatggcaatg
     4681 acgcctacac ctctacaact gatggtgatt acttttacac aacagctgtc tttgccgatc
     4741 gtattgactg ctacaagtat gaccgccact tgaaaaaaca ggctcacaag tctattctaa
     4801 atcaagacac cattaatgcc agcaatcagt ttctggtgat tgatgacgct ctgtacctgc
     4861 ttgtcagcgc tgtagacatc aagagtcagc agcccaaaac tgagctatgg aaaatggaca
     4921 aatcctttac tatcactgat cggatagatc tggacgaaag cactgcctat ctgcgcatgg
     4981 tcaacgtcgg acgaaccctt tacattaccc aggctgctga tggcatttta gaaactggag
     5041 aacctagacc tggtaacaag gtgatgacct atgacttaga tagcggtcaa aagtcctatc
     5101 tcatgcttca tgtcaatagt cctagagcca tttaccacca tgccaaaacc aatgagctta
     5161 tcatcgaaaa tgatcagcat tataatcctg actttgcatg gaccatctac cagctagata
     5221 ccggagagga gagaaccatt cgctttgagg agctagccgg tcaggagaca agctctccct
     5281 actttatgat gacctcaagc aactactact tcctctttcc aaaaaggctt taccgatacg
     5341 attgtagtaa ccatcagatg acctgcatca acctagatca gtacggagtg acgcacgccc
     5401 atgccttgat cgctaagccc acaccataaa tcacaacagg cctaatcacc actcattcat
     5461 ctacacccca atgcttagac aaagcagtgt actgaccccc aaaagttgga cacgacatat
     5521 tagtgaaagg atttagttct gtattgcaca gggctaagtc ctttcactaa tatgtcgtgt
     5581 ccaacttttg ggggtcagta cactttggga aagtatgtat gaatctccag aaaaaatacc
     5641 ttatcaacta cctctatatg acaagtatga gggaaataat agtttattta gagataatgc
     5701 ctcaccaaat tttagggcgg atgtcaaaga tattacagct actttagtgg ctgttttaag
     5761 taatggttat ccaaccggga aaagcagttt ttgtaaagac tactgtcccg atgaaatcag
     5821 ggcaagacaa ttaacccaat tagctatttg gtattttaca gatggtattt ctgaagaaac
     5881 gttgaaatca aattatagtc taaatgatct tgaatttcaa ggattaaagt atttaataca
     5941 ggctggcaaa actgctggga ctagtaacaa tcg
//
LOCUS       DARYXS010000103         5866 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.104, whole genome shotgun sequence.
ACCESSION   DARYXS010000103 DARYXS010000000
VERSION     DARYXS010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5866
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.104"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            175..963
                     /locus_tag="TV193_001707"
     CDS             175..963
                     /locus_tag="TV193_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1513881.1"
                     /translation="MARGRGRLTPQEIEALGFFSSKFNDLLNETNTKQVELSKATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADYFGLMKSDIDPRFAPRKKNHELKIPTSPLVKKIT
                     TTVVELNVPRKQKVLDFATDQLKEQKNKMTSMEKKLYEYKVYEKLSAGTGYGYFGDGN
                     YDTVFYEEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGVYAVEWDGQTYIK
                     KVYREKDGLRLVSLNKKYKDKFAPFSEDPRIIGKIVGNFMPKEY"
     gene            972..2141
                     /locus_tag="TV193_001708"
     CDS             972..2141
                     /locus_tag="TV193_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEL1513882.1"
                     /translation="MGLFNFGKIKDVALEKKLQKLQQKIENEKEKLREIKEEIALAND
                     TLDLQEYGFFERQYKFSHSTKYKDALDTLRMKQKTLIKNGEATSIISPMTLDGSAAKG
                     KAMQNQLRKAAIRGFNGEADALLVKVSVVNVDKKVQTLQKAFEQLNKMYERNLIQLTF
                     KYLDLKAQELRLAAEYELQKQEEKEILREQRAREREDKKLQAEITAKRKQLEKDRKHF
                     LQMVKNVEVMLANASPKEQEKLQLQLIEYQNKLSELDKIEEDIDYREGHATAGYVYVI
                     SNIGAFGEDVYKIGVTRRLDPMDRIRELGSASVPFTFDVHALIFSEEAFALESELHNK
                     FEAYKVNKINSRKEYFRVPFAKIKEVLENHKELAIEITEEAEAFEYRQSILKNGG"
     gene            2144..2347
                     /locus_tag="TV193_001709"
     CDS             2144..2347
                     /locus_tag="TV193_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513883.1"
                     /translation="MKWLFLILFIGCGANAVNLSKKVNSDDEVDENNSHLISHSNEEI
                     PWNKKEQLYWGTASIVFLVLFII"
     gene            2479..3912
                     /locus_tag="TV193_001710"
     CDS             2479..3912
                     /locus_tag="TV193_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1513884.1"
                     /translation="MITTRKVAIYVRVSTTNQAEEGYSIQGQIDSLIKYCEAMGWIIY
                     EEYTDAGFSGGKIDRPAMSKLITDAKHKRFDTILVYKLDRLSRSVRDTLYLVKDVFNQ
                     NNIHFVSLQENIDTSSAMGNLFLTLLSAIAEFEREQITERMTMGKIGRAKSGKTMAWT
                     YTPFGYDYNKEKGELILDPAKAPIVKMIYTDYLKGMSIQKIVDKLNKMDYNGKDCTWF
                     PHGVKHLLDNPVYYGMTRYNNKLFPGNHQPIITKELFDKTQRERQRRRLGIEENHYTI
                     PFQAKYMLSKFLRCRQCGSRMGLELGRPRKKEGKRSKKYYCLNSRPKRTASCDTPLYD
                     AETLEDYVLHEIAKIQKDPSIASRQKHIEDHELKYKRERIEANINKTVNQLSKLNNLY
                     LNDLITLEDLKTQTNTLIAKKRLLENELDKTCDNDDELDRQETIADFLALPDVWTMDY
                     EGQKYAVELLVQRVKVDRDNIDIHWTF"
     gene            complement(3942..5111)
                     /locus_tag="TV193_001711"
                     /pseudo
     CDS             complement(3942..5111)
                     /locus_tag="TV193_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            5167..5808
                     /locus_tag="TV193_001712"
     CDS             5167..5808
                     /locus_tag="TV193_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEL1513885.1"
                     /translation="MEDYKTIMTDGLFEESIKKSRFICQIKRVYTEEEARAFIADIKK
                     KHYKANHSCSAMIIGDKGQTKRSSDDGEPSGTAGIPMLSVLERQELTNLVAVVTRYFG
                     GVKLGAGGLIRAYSGVTAAAIQALKVVEVKKQTGLAISLTYPQYQIYPNFLEQEALIE
                     MNTEFSDVVRTAIYFDPERLESISKALIEHYHGKVSFEEIESQRIEVPVLPAN"
BASE COUNT         2050 a         1006 c         1171 g         1639 t
ORIGIN      
        1 ctcctttggg agtctttatt ttgcttaatt ctttaagctt gattatatta taattcgaat
       61 taaaacgtat gtcaatagca tttacgaaaa aaatcgtatt tattttaaaa atactattta
      121 caaatacgat ttaaagcgat atcatatgag tataaaaatc gaaaggaaaa taatatggca
      181 agaggaagag gtagattaac acctcaagaa atagaggcgt taggattctt ttcgagcaaa
      241 ttcaatgatc tgctcaacga aacaaataca aagcaagttg aactctcaaa ggctacagga
      301 ataccaccaa gtacgctcac aggttacgta aaagggacat ctttacctat tcccggtaat
      361 gtccaaaaaa tagccgatta ttttgggtta atgaaatcag atatagatcc aagatttgca
      421 cctcgtaaga aaaatcacga acttaagatt cctacttctc cacttgtcaa aaaaataacc
      481 acaactgtcg tggaattaaa tgttcctcgt aagcaaaaag ttttagactt tgcaacagat
      541 caattaaaag aacaaaaaaa taaaatgact tctatggaga aaaaactcta tgagtataaa
      601 gtttacgaga agctttcagc tgggacaggt tatggatatt ttggtgacgg gaactatgat
      661 actgtctttt acgaagaaga attagactac gatttcgctt cttgggtttt cggcgattct
      721 atggagccca cttatttaaa tggtgaagtt gtgcttataa agcaaactgg ctttgattac
      781 gaaggcggtg tctatgctgt tgaatgggac ggacaaacct atattaagaa agtttatagg
      841 gaaaaagatg gattaagatt agtttcttta aataaaaaat acaaggataa gtttgctcct
      901 tttagcgaag atccgcgtat aatcggcaaa atcgtcggca actttatgcc caaagaatat
      961 tgaggtgtgt tatgggattg tttaatttcg gaaaaataaa agatgtggct ctagaaaaga
     1021 aattacaaaa gttacaacaa aaaattgaaa atgaaaaaga aaaattgagg gaaattaaag
     1081 aagaaattgc attagccaat gatacattag accttcaaga atatggtttt tttgaacgcc
     1141 agtataaatt ttcccatagt actaaatata aagatgcttt agatacgtta cgaatgaaac
     1201 aaaaaacact cataaaaaat ggtgaagcta caagcataat ttcccccatg actctagatg
     1261 gtagtgcagc aaaaggtaaa gcaatgcaga accaacttag gaaagctgca atccgcggct
     1321 ttaatggtga agccgatgcc ttactagtta aagtgtctgt cgtaaatgta gataaaaaag
     1381 tgcaaactct tcagaaggct ttcgaacaat taaataaaat gtatgaaagg aacttgatcc
     1441 aacttacctt taaatattta gatttaaaag cacaagaatt gagattagct gctgaatacg
     1501 aattgcaaaa acaagaagaa aaagaaattc taagagaaca gcgtgcaaga gaaagagaag
     1561 ataaaaaact tcaagctgag attactgcta aaagaaaaca acttgaaaaa gacaggaagc
     1621 actttttaca aatggtcaag aacgtcgaag tgatgcttgc taacgcttct ccgaaagaac
     1681 aagagaaatt acaattgcaa ttaattgaat accaaaacaa gctctcagaa cttgataaga
     1741 ttgaagaaga cattgattat agagaaggac atgcaacagc tggatatgtc tatgttattt
     1801 ctaatatagg tgcttttgga gaagatgttt ataaaattgg agtaacaaga cgtttagacc
     1861 caatggatcg tattcgcgaa ttggggagtg catcggtgcc ttttactttt gatgttcatg
     1921 cgcttatctt tagtgaggaa gcttttgctt tagagtctga gttacataat aaatttgaag
     1981 cgtataaagt aaataaaata aacagtcgaa aagagtactt tagagttccg tttgctaaaa
     2041 tcaaagaagt tctagaaaat cataaagaat tagctattga gattaccgaa gaagctgaag
     2101 cgtttgaata ccgtcaaagt atcttgaaaa atgggggtta aatatgaaat ggttattcct
     2161 aattttattt ataggctgcg gtgctaatgc tgtaaacctt tctaaaaaag ttaattccga
     2221 tgatgaagtt gacgaaaaca acagtcacct tatatcacat tcaaatgaag agattccttg
     2281 gaataaaaaa gaacagcttt attggggcac tgcttccatt gtatttttag tgctttttat
     2341 aatctaaaca caataataaa aagcctcacg ctcaactttg gtcgatgcga gcgtgaggcg
     2401 aacgtgtata gtaaaaacct gctttgcagt aggtctcttt actataccca ttttaacata
     2461 aaaatgaggt gaaaaacaat gattacaaca agaaaagtcg ctatttatgt tagagtcagt
     2521 acaacaaatc aggcagagga gggctattca atacaaggtc agatagacag tttgatcaaa
     2581 tactgcgaag ctatgggttg gattatatat gaggagtaca ctgatgctgg cttttcagga
     2641 ggtaagatag accgtcccgc catgtctaaa ctaattacag acgcaaagca taaacgattt
     2701 gatacaatct tagtttataa gctagacaga ctctcccgaa gtgtcagaga tactctttac
     2761 ttagttaaag atgtttttaa ccaaaacaat atccattttg tcagtctgca agaaaatatt
     2821 gacacttctt cggctatggg taatctattc ctcacattgc tatctgcaat tgccgaattc
     2881 gaacgagaac agataacaga gagaatgaca atgggaaaaa tcggaagagc aaaatccgga
     2941 aaaactatgg cctggactta tacccctttt ggctatgatt acaacaaaga aaaaggcgaa
     3001 ttgattttag atcctgcaaa agcgcctata gttaaaatga tatatacaga ttatctcaaa
     3061 ggtatgtcta ttcaaaaaat agtggataaa cttaataaga tggactacaa cggtaaggat
     3121 tgcacttggt ttccacatgg tgttaagcat ctattagata atcctgtcta ttatggtatg
     3181 acaaggtata ataataaatt attccccgga aatcatcaac caattattac aaaagagcta
     3241 tttgataaaa cccaaagaga aaggcaacgc agaagattag gaatcgaaga aaaccactac
     3301 acaatacctt ttcaggcgaa gtatatgcta agtaaatttt taagatgtcg tcaatgtggc
     3361 tcaagaatgg ggcttgagct tggcagacca agaaaaaaag aaggcaaaag atccaaaaaa
     3421 tactattgcc taaatagtag gccaaaacga acagctagtt gcgacacacc actttacgat
     3481 gcagaaacct tggaggatta tgtgttacac gagatagcca aaatacaaaa agatccgtca
     3541 atagcgagca gacaaaaaca tattgaggat cacgaattaa aatacaagcg tgaaagaatt
     3601 gaagctaata tcaataaaac agtgaatcaa ctctctaagc taaacaatct ttatcttaac
     3661 gatctgataa ctcttgaaga cctcaaaact cagacaaaca ctcttatagc taaaaaaaga
     3721 ttgctagaga acgaactaga taaaacttgt gataacgatg atgaacttga cagacaagaa
     3781 accattgctg actttctcgc cttgcctgat gtatggacca tggactatga gggtcaaaaa
     3841 tatgctgttg agctgcttgt tcaacgtgtt aaagttgata gagataatat agacattcat
     3901 tggacttttt aatgccaaaa attacaaagt tttcaaccct tgatttgaat aagactgctg
     3961 cttgtgtaaa ggcgatgatt ggctaataag acaaagacat ctacggttgg aaaggtcaca
     4021 cctctttcca aaatggttgt tgatataagt atagtgattt gtccttgtct gaattgctca
     4081 atgatagcca ttcgatttga tgactgactg gaagcatgag caatagtttc cttaggaaaa
     4141 tacttgtgga gcagctgaca gcattgctca gccagctcaa taatcggaaa aaagattaaa
     4201 agaggatagc cggttgccct ttgttttttg actagggtga tgaaccttct aggcaatttc
     4261 ccacgattga tagcctctaa aagggagaat aatctttgat actttggaac aactaagggc
     4321 ttgccatgga atcttcttgc caacgtcaat ttgacaagct ctttttgctt gaccttgcgc
     4381 tctaaatctc ttgtagaggt tgctgttagg tatactgtca ctgcatctgc ttttgcagcc
     4441 tgatgagcag catggtttaa ttgacgatta ttgacaaagg ggaaggcatc tacttcgtca
     4501 ataatgagca gatcaaaagc atggtaaaag gtcatcaatt gatgtgttgt ggcaacgata
     4561 atggggcttc tatgataaac ctctgactca gcatgcataa ggcagacttg acaggaaaag
     4621 tcccgcgata gtcgtttttc aagctctatg caaacatcaa ctcgtggact agcaatgcag
     4681 acccagccac ccttattaac aactgctgca atagcttcat acatcatctc tgttttgcca
     4741 gcaccagtaa ccgcatgaac taaggtgtct tgcttgagct taacatggtt agtaagctga
     4801 tgagagatag ctgcctgata tgtcgtgagc tgtccttgcc acctcagata atgtcccttt
     4861 ggaaaagaag ccggtggaaa atagagcaag gggcgatcag attggtttcg accaaaaaca
     4921 agacaggctc tacagtagta agcaccgcta ggcagctgat gagccttctc aattaaactg
     4981 ctacagcgtt ggcagtataa cgttcccttt ttagtgatca tgctttgtaa gctgcaagcc
     5041 caggcagaaa cagcctttgg gcattgcctt tcgggtaaaa gacgtccata gtaattttcg
     5101 atattctcca taccttatta tccgaattat tttgctaaat atcagcattt tttgtaaaat
     5161 tttcttatgg aagattataa aactattatg actgatgggc tttttgagga aagcatcaaa
     5221 aaatctcgct ttatttgcca aatcaaacgc gtctacacag aagaggaggc cagagccttt
     5281 attgctgaca tcaaaaaaaa gcactataag gccaatcatt cctgctctgc tatgattatc
     5341 ggagacaaag gacaaaccaa gcggtcaagc gatgatggtg agccatctgg tactgctggt
     5401 attcccatgc tatctgtctt agaaaggcag gaattaacca atcttgtagc tgttgtgaca
     5461 cgctattttg gaggtgttaa attaggagct ggagggctca ttcgcgctta ctccggcgta
     5521 actgcggcag ctattcaggc cttaaaggtc gttgaggtaa aaaaacaaac tggactagca
     5581 atcagcctca cctaccctca ataccaaatc tatcctaatt ttctggagca agaagcattg
     5641 attgaaatga ataccgaatt ttctgatgtc gtcagaacag ctatttactt tgatcctgag
     5701 cgcttggaga gtatttctaa ggcattgatt gagcattatc atggcaaggt ttcctttgaa
     5761 gagatcgaat cgcaaaggat tgaggtccct gttttgcctg ccaattagca tgaacagtga
     5821 tagcgtctct ttatcactac gatagtaaat ggctatttta ctttgt
//
LOCUS       DARYXS010000104         5728 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.105, whole genome shotgun sequence.
ACCESSION   DARYXS010000104 DARYXS010000000
VERSION     DARYXS010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5728
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.105"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            181..873
                     /locus_tag="TV193_001713"
     CDS             181..873
                     /locus_tag="TV193_001713"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEL1513886.1"
                     /translation="MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNE
                     RLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKL
                     GRGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKD
                     YKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDHLSKGTGRSKKLAEQD
                     AAKNALAQLSEV"
     gene            874..4425
                     /gene="smc"
                     /locus_tag="TV193_001714"
     CDS             874..4425
                     /gene="smc"
                     /locus_tag="TV193_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEL1513887.1"
                     /translation="MFLKEIQMQGFKSFADKTKIIFDKGVTAVVGPNGSGKSNVTESL
                     RWALGEASAKSLRGGKMPDVIFAGTEHRSPLNYAEVAVVLDNSDAFIKNAQKEIRVER
                     HIYRNGDSDYLIDGKKVRLRDIHELFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTARQFLAL
                     DADRKQLQLDILVKDIEQDRMEQEAQEKALVALREDLAAYHRKRQSLEAENHRLKTKR
                     QKLSAVAEQTQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLA
                     FQQEHQQKSRQLDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVGLLQQE
                     ADVSNQLTAIVAQLDKESQAKASQAQEYQVLQEKVNQLSQDTQTALLAYQASQSRLEQ
                     LLADYQELAKTVEALEQDYHQGQTRLFDLLDQKKAKEARRASLVSIQKNHSQFYAGVR
                     AVLQAAGKLDGILGAVSEHLTFDSQYQTALEIALGASSQHIIVADEAAAKRAIAFLKA
                     NRQGRATFLPLTTIKARQLSEVTLKQLRACQGYLGTADSLVTYEPSLVAIVQSLLGVT
                     AIFDTIDHANQAAKQLHYKVRIVTLDGTELRPGGAFSGGTNRHNSTTFIKPELEQIEK
                     ELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQLAEKL
                     ADSKELLELLSNRQTGQSSERLLSEKARLEEALQLLADEKSALTSEIEQIKENKDTIK
                     QKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLSHQVSQ
                     EAIDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAF
                     IRQQARLEADLEQVIGRLRQHARSLSEELQLSLEEAKEQASPINDTDMAAARQKLQQV
                     QQSIRALGPINSDAIAQFDEVSERLAFLNGQRADLIKAKNLLVDTIGNMDHEVKARFR
                     VTFEAIRDSFKETFRQMFGGGSADLMLTETDLLSAGVDISVQPPGKKLQSLNVMSGGE
                     KALSALALLFAIIRIKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRK
                     GTMAAADSIYGITMQESGISKVVSVKLKDTQDLTYLS"
     gene            4790..5233
                     /locus_tag="TV193_001715"
     CDS             4790..5233
                     /locus_tag="TV193_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513888.1"
                     /translation="MMTVKTNKQRLWLGLIIVIGAIIMVFRLNGKRTEEQQKRDLETS
                     IAKLLVHDYEGVKEVKFTGWGHSRETGSWGTIVIINGENEIGFSFDGLSSLEKIRGIV
                     TDDDTEKMEKPETDTKPRIMDRIDKINKTSLVGVTVIYSKDNQED"
     gene            5235..>5728
                     /locus_tag="TV193_001716"
     CDS             5235..>5728
                     /locus_tag="TV193_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513889.1"
                     /translation="MAISDSSYNELAKQVYNVEPSKAKSNGDLVIVAGKTVKDPITKR
                     QYRVLLVQDNNNDAHKTNDNGMQAMAVAPIVKGDIDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIV"
BASE COUNT         1730 a         1049 c         1449 g         1500 t
ORIGIN      
        1 caaggggttg agtaaggtgt ggactaaaac aagtgataaa gtcgggaaat agcagcagtc
       61 aatagctcgt gcctatttgg tacaatattt ctgaaaaatc cacttgtgat aagcctttca
      121 agtggatttt tgttataata gaatggttta taaggacatt agaaaaggag atttgtcatg
      181 atgaaaaagc ttgaggccct gctggaaaac tcttttaata tccgttttga tgataaaaga
      241 ttactagaga ctgcctttac acatacctct tatgctaatg agcatcgcct cctaaacatt
      301 tcacataatg agcgtttgga atttttagga gacgccgttc tacagttaat tatttcagaa
      361 tacctctttg ccaagtatcc taagcagact gagggtgata tgtcaaaact cagatcaacg
      421 attgtcagag aggaaagctt agcaggcttt tcacgctatt gttcgtttga tgcttatatt
      481 aagcttggca ggggcgagga aaaatcagga ggccgtcatc gtgatacgat tttaggcgat
      541 ttgttcgagg cttttttggg tgctcttctt ttggataaag gcattgaaga ggttcgtcgc
      601 tttttaaatc aggttatgat tccacaggtt gagcagggaa cttttgagaa ggtcaaggat
      661 tataaaacct gcttgcagga gttgttacag gctaagggtg atgttgtgat tgattatcag
      721 gtgattagcg agactggacc agctcatgct aagcaatttg aggtagctgt attggttggt
      781 gaggatcatc ttagcaaggg gacaggtaga tctaaaaaac tggcagagca ggacgctgct
      841 aaaaatgccc tggcccaact tagtgaggtc taaatgtttt taaaagaaat acaaatgcag
      901 ggctttaagt cttttgcaga taagaccaag attatctttg ataagggggt cacagctgtt
      961 gtagggccaa atggctctgg aaaaagtaat gtgacagaaa gccttcgttg ggcacttggt
     1021 gaggccagtg ccaaaagcct gcgcggtggc aagatgccag atgtgatctt tgctggaact
     1081 gagcatcgga gtcccttgaa ttatgcagag gtggctgttg tcttggataa ttcagatgcc
     1141 tttattaaga atgctcagaa agagattcgt gtggagaggc atatctatcg caatggcgac
     1201 agtgattatc tgattgatgg caaaaaagtt aggctaagag atattcacga gctgtttatg
     1261 gatacaggac tagggcgcga ttcgttctct attatttctc aaggtcgtgt tgaggagatt
     1321 ttcaatagta agccagagga aagacgggcc atctttgaag aggcagctgg agttttgaaa
     1381 tacaagaccc gcaagaagga gacgcaaact aagctaaacc aaactcaaga taatcttgac
     1441 cgcttagacg atattatcta tgagcttgag catcaagctg gtcctctaga aagacaggcg
     1501 aaaactgcta ggcaattttt agccttagat gctgatcgta agcagctgca gctggatatt
     1561 ttggtcaagg atatagagca agaccgcatg gagcaggagg ctcaagaaaa ggccttagta
     1621 gctcttcgtg aggatctagc ggcctatcat aggaagcgtc agagtctaga ggcggaaaat
     1681 caccgtctaa aaaccaagcg gcaaaagctc tctgctgtag ctgagcagac gcaggctgat
     1741 ttgctagaat tgacaaaggt catatcagat ctggagcgac agattgacct catcaagctg
     1801 gaccttagtc aaaagcagga aaagaaaaca gaagccagtc agcgcaggca gcaggctcag
     1861 gagcaattgc ttgcctttca acaggagcat cagcaaaaga gtcgtcagct agatgaaatc
     1921 catcaagcct tagctgagtt taataccaag gtcagcgagc tttctcagga gcttgagcga
     1981 ttttctagcg atccagatca gctgcttgag gctcttcgtg aggattttgt tggtctgctc
     2041 cagcaagagg ctgatgtgtc aaaccaatta accgctattg tagcgcagct ggataaggaa
     2101 agtcaggcga aagccagtca ggcgcaggaa taccaagtcc tacaagagaa ggtcaatcag
     2161 ctcagtcagg acacccagac tgctcttttg gcttatcaag ctagtcaatc aagacttgag
     2221 cagctcctag ctgattatca agagctagca aagacagttg aggccttgga gcaggattat
     2281 catcagggac agacaaggct ttttgatttg ttggatcaga aaaaagccaa ggaggctcgt
     2341 agggctagtt tggtttctat ccaaaaaaat catagtcaat tttacgcagg tgttagggca
     2401 gtgcttcagg ctgctggtaa gctagatggt attttaggag cagttagtga gcatttgacc
     2461 tttgatagtc agtatcaaac ggcacttgag attgctttgg gagctagtag tcagcatatt
     2521 atcgtggcag atgaggcagc agccaagcga gcgatagcct ttttaaaggc taatcgtcag
     2581 gggcgtgcga cctttttacc tctgacaacg attaaggccc gtcagctttc tgaggtgact
     2641 ctcaagcagc tcagggcttg tcagggctat ttaggcacag ctgattcttt ggtgacctat
     2701 gagccctctt tggtcgctat tgtacaaagc ctgttaggtg tgacggctat ttttgatacc
     2761 attgatcatg ctaatcaggc agctaagcag ctgcattata aggtcaggat tgtaacgctt
     2821 gatggtaccg agctgcgtcc cggtggtgcc ttttcagggg ggactaatcg tcacaatagc
     2881 acaaccttta tcaagccaga gctagagcag attgagaagg aattagcctt gctttctgag
     2941 cagatcaagg aatctgaaaa agcagtagct gctgtacagg ctgatttgaa ggctaaaaag
     3001 gctgcgcagg ctgatactaa gctggctggt gagcaagcaa gactggtcga gcaaaaaaca
     3061 caattggcct atcagcagct agcagaaaag ctggctgact caaaagagct gctagagctt
     3121 ctcagcaacc gtcagactgg tcagtctagt gagcgcttat tatcagaaaa agcgaggctg
     3181 gaggaggcat tgcagctcct agctgatgaa aaatcagcct taacgtcaga aattgagcaa
     3241 attaaggaaa ataaagatac gattaagcaa aagaaggacc agcttagcca ggaattatct
     3301 caggctcgtc ttaaagagcg agatttgctc aacgagaaaa agtttgaagc agctaaccag
     3361 cgtcgcttgg agacgatgat tgctcagggt cagaaggaat tagctaattt ggagactgtt
     3421 ttatcacatc aggttagtca ggaggccatt gaccaattgc ctcacctaga aaatcagctg
     3481 acagaggcta atcaagacaa gatcaagact caggagcgct tcattcagct gcgctttgaa
     3541 ggtgaggact atgacgccag actggaggag ctagaggctc aattgcttaa ggaagccaag
     3601 aaaaatgaag cgttcattcg tcagcaggca agactggagg ctgacttaga gcaggttatt
     3661 ggtcgtttgc ggcagcacgc tagaagccta tcagaggagc ttcagctaag cttagaggag
     3721 gccaaggagc aggcaagccc aatcaatgac actgacatgg cagcagcaag acagaaattg
     3781 cagcaggttc agcaaagcat tcgtgcccta ggcccaatca atagtgatgc tattgctcaa
     3841 tttgatgagg ttagtgagcg tttggccttc ttaaatggtc aaagggctga ccttatcaag
     3901 gccaagaatc tcttggtaga tacgattggc aatatggacc atgaggttaa ggcacgcttt
     3961 agggttacct ttgaggctat tcgtgatagc tttaaggaga cctttaggca gatgtttggc
     4021 gggggctcag cggacttgat gttgacagag actgatctgc tttctgctgg agtagatatt
     4081 tcagtgcaac cgcctggtaa aaagcttcaa tctttgaatg tgatgtctgg cggagaaaaa
     4141 gccttatcag cgctagccct tttatttgct attatccgca ttaagaccat tccctttgtg
     4201 attttagatg aggttgaggc ggcccttgat gaggccaatg tcaagcgttt tggagattat
     4261 ctcaatcgtt ttgacaagga tagtcagttt atcgtggtta cccaccgcaa ggggacaatg
     4321 gcagcagcag acagtattta tgggattacc atgcaagaat ctggtatttc taaggtagta
     4381 tctgttaagc tcaaggatac gcaggatctg acttacttgt cataactcta ggacagagct
     4441 tagttttagc tgtatttcta catgtagcag atgataacca agaataagct ataaaaaaac
     4501 ctatcgtcat ggtaggtttt ttggctttcc aaaggacaaa gcacaaggat tggctagcag
     4561 taagctgctg tttttgacat gctcctggaa cttagtacgg cttgttttga ttaaaatata
     4621 ccaaaaaagt aactaaggac ataatatatt gacaagtaga tgtctgtata ttataattta
     4681 attacaaaat gagaataata taaataagat ttggcgttga tttcacccta attagtcatg
     4741 ctgccttcct tagagtgacg gacgcatagc aaaagagtga aaggaggaca tgatgacagt
     4801 taagaccaat aagcaaaggc tatggctagg cttaataata gtaataggag cgatcataat
     4861 ggtttttcgt ttgaatggca aaagaacaga ggaacaacaa aaaagggact tggaaaccag
     4921 tattgctaag ctgctggttc atgactatga aggggttaaa gaagttaagt ttacaggctg
     4981 gggacattct cgggaaacag gttcgtgggg aacgatagtg attataaatg gagaaaatga
     5041 aataggcttt tcgtttgatg gcttgtctag tcttgagaaa atacgaggaa ttgttactga
     5101 tgatgataca gaaaagatgg aaaagcctga aactgatacc aaaccaagaa ttatggatag
     5161 gattgacaag attaataaaa catctcttgt aggtgttact gtcatttatt caaaggacaa
     5221 tcaggaggat taatatggcg atatcggata gtagttataa tgagttggct aaacaggttt
     5281 ataatgtcga acctagcaaa gctaaatcaa atggagacct tgttattgtt gctggtaaaa
     5341 ctgtaaaaga tcctatcact aaacgacaat accgagtcct cttagttcag gacaataaca
     5401 acgatgccca taaaaccaat gacaacggta tgcaggcaat ggctgtagcc cctattgtta
     5461 aaggtgatat cgatacctct caggttgtga ttgcctatgc agggacaaat gctgcggatt
     5521 ccagagatct tgatacggat tggcagctgc tcattcgggg caatcaagat gatttagtca
     5581 gcggcaatat tgatggtggc aattttgtta ttgccgaaaa ccaattacga tctgctcaaa
     5641 agttttatca acaggtcaaa agaaagtacc ctcattctgc cttaacaacc acaggtcact
     5701 ctctcggagc ttatctagca ctaatagt
//
LOCUS       DARYXS010000105         5630 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.106, whole genome shotgun sequence.
ACCESSION   DARYXS010000105 DARYXS010000000
VERSION     DARYXS010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5630
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.106"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(484..2061)
                     /gene="cls"
                     /locus_tag="TV193_001717"
     CDS             complement(484..2061)
                     /gene="cls"
                     /locus_tag="TV193_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEL1513890.1"
                     /translation="MTIKKNKKVRYLLHKGKKGLLRGIFSRTTIIAALIVLQIFFLCQ
                     SYAWMEQYRVLIAIIERIFSISIVLYLVNSDMDAISRVTWLILIMIAPLLGSLFLIYT
                     KLDWGYRDLKQRINHLVDLSSPYLRDDDAILQALKGHTSTTYHLVQYLERSRGNFPIY
                     RKTQATYFPIGEAFFEGLKTQLLLAKSYIFLEFFIIAEGQMWGEILGILEKKVQEGVE
                     VRVLFDGMLELSTLSADYAARLERIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     AFTGGINLADEYINEVKRFGHWKDAGLMLKGEAVDSFLIMFLQMWSITEKRLIVEPYL
                     SQHTEEVASDGYVIPYADSPLDTDKIGRNVYIDILNHAKEYVYIMTPYLILDSETEHA
                     LRFAAERGVDIRIIMPGKPDKAVPYALAKTYYKGLITSGVKIYEYSPGFVHSKVFISD
                     DSKAVVGTINLDYRSLYHHFECATYLYRSSVIADIVQDFKETQASSKLVTESQLRQRP
                     WYQKLVGLLVKTIAPLL"
     gene            complement(2277..5617)
                     /locus_tag="TV193_001718"
                     /pseudo
     CDS             complement(2277..5617)
                     /locus_tag="TV193_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677995.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
BASE COUNT         1610 a         1261 c         1065 g         1694 t
ORIGIN      
        1 tgacagagtg tttcctgaat ttttatattt ttcctctata aacttttctt gaaaaatttc
       61 ttttctgcaa ctatcgctat ggctttccta tttttcagaa caagttttcg catttcagaa
      121 atatcttgga aattttttct tcatgcgttt gtcgtagcta gaagcttatg gtatgacagt
      181 caatagataa gtttttcaca tcagtgctat tgttccatga taacataccc ccttagaaaa
      241 ggcagttatg ctatggatac gatgagactc acacctaaca cagtgagatg actaaacatc
      301 acaacaaaaa aagctgagag aaactctcag ctctcagggg cattcgtatc acgaatgtga
      361 taaaaaggtt cacacaaatt atcaaagtcg gctcctgcct taatgacctc cccagcacaa
      421 ctgtgattta aaaatcacaa tcgactcatc gcataggcct attatagcaa acatatcatc
      481 tctttacaag aggggggcta ttgttttaac caataaacca acgagctttt gataccaagg
      541 cctttgcctt agctgacttt ctgtgactag cttagagctt gcctgggttt ctttgaaatc
      601 ctgaacaatg tctgcaataa cagaggaacg gtaaaggtag gtggcgcatt caaaatgatg
      661 atagaggctg cgataatcca gattaatggt tccaacgact gccttagaat catctgaaat
      721 aaagacctta gaatgcacaa atcccggact atattcgtag attttaactc ctgaggtgat
      781 caagccttta tagtaggttt tagcaagggc ataaggaaca gccttgtcag gcttacctgg
      841 cataataatc cgaatatcca cccctcgctc tgctgcaaat ctgagggcat gctctgtttc
      901 gctatccaaa atcaggtatg gagtcatgat ataaacatat tccttagcgt gattcaagat
      961 atcaatatag acatttctgc caattttgtc agtatcaagt ggtgagtctg cataaggaat
     1021 gacatagcca tctgaggcga cctcctctgt atgctgggac agataaggct ccacgatcag
     1081 ccttttttcg gtaattgacc acatttgtaa aaacatgatc aaaaagctat caacagcctc
     1141 accctttagc ataagacctg cgtccttcca atgcccaaag cgtttgacct cattaatgta
     1201 ctcatcagct aggttaatac cgcctgtaaa ggccacctct ccatcaatca ccacaatttt
     1261 acgatgatcc cgataattgt agtaggttga aataaaaggc gagatcggca aaaaagactt
     1321 tgctttgata ccaatgcgtt caagtctggc agcataatcc gctgataagg tcgacagctc
     1381 tagcatgcca tcaaaaagaa cgcgaacctc tactccctct tgcaccttct tttctaaaat
     1441 tcctaaaatt tctccccaca tctgcccctc tgcaatgata aaaaattcta gaaaaatata
     1501 ggacttagcc aataaaagct gagtttttaa accttcaaaa aaggcttctc cgatgggaaa
     1561 gtaggtggct tgagtcttgc gataaatggg aaaattccca cgactacgct ctaaatactg
     1621 aacgaggtga taggtcgttg aggtatgccc cttcaacgcc tgtaaaatag cgtcatcatc
     1681 tctcaagtaa ggagaggaca aatcaactaa atggttaatt cgctgcttta ggtcacgata
     1741 accccagtct aatttagtgt aaataagaaa taaagagcct agtaaagggg ctatcataat
     1801 gagaatcagc caggtcaccc ttgaaatagc gtccatatcg ctattcacca agtacaagac
     1861 aattgaaatc gaaaaaatac gctcaataat agcaattaaa acacgatact gctccatcca
     1921 agcataggat tggcataaaa agaagatttg cagaacgatc aaagcagcaa taatggttgt
     1981 tctgctgaaa atccccctca gcaagccttt tttcccttta tggagcaggt atcttacttt
     2041 tttattcttt ttgatagtca accctccagc tttatttttt cttattatat cataaaactg
     2101 gaggtcatga tttaagtcgc tgctaaaagt ttcagcaatt ggtgcaagca ttaaaaaaag
     2161 acctcaatac ttcttttaca acttgtaatc ctcacaaaac ctactgcttt aacaaccaaa
     2221 aaaagattga aggagacatg cttccccttc aatccaagtc tcatcaggtg atgagattaa
     2281 ttatctgatt tctttttaaa taagcctaga gataggctag ctagtagcat acctaagcct
     2341 gctaataacg atgagcccta tgcctgctct gaggttttag gaagctcatg gctatgtgct
     2401 ggagccattg gtttgctgct atctggtgtc atggctagtg actgctgatc tgctttgcta
     2461 ttatcagaag actgatcttg atcagtagaa ccattgccct taggctgctg ctctggcatt
     2521 ggtgtctcag gctgtttgtc gtctttaatc tctggttcct tttggtttaa aaggtctgta
     2581 agagcaatcg cgttaaagtt gccaaattca tcttcaacaa ttaatgtcaa ggcagcaata
     2641 ttaacctcta cctcctcacc tgacagctct gacatcaccg ttgctggaat gctaaatgag
     2701 ccgtcctcag ccattgggaa gtagttcacc acaatatctg cttcctctcc ttctccaatc
     2761 tcgacaatat ggccaacctg aatacggtag gctgagaatt tagcagtgtc gatcttaagt
     2821 gttctggtag attcgtcata ggaagctgat tttggtagct ctggtaggct tgttttcact
     2881 tgaaccttaa agtcttgctt ttgagcctca gcaccatctg ctacaggagt ataccaaacg
     2941 cgataggtat agctaccatc tgctacaggc tgatcattgg cgtcttttcc actccatttt
     3001 gtatgctcaa agcgatacgg taacacaaca ccctcttgat agtatttctg ggctgaagaa
     3061 acaccacttt cccaaacgat ttgtccattg tgatcaagaa cctgagcttt aatatcctta
     3121 acgcttctta ggaatacccc ttggaagaga ataaaatcct tattaccatc atcatttgga
     3181 gaaatcaaga aggttctatc tgcctctttt gctattaaat ccttttgatc agctgactcc
     3241 tgtgttccta aaataatata tctttctgcc tcagggccta actcattgac cgttccattt
     3301 tttgtatcct gtgccaagaa atatgggctg acctgaccaa tcaaagcagt tagcttgctg
     3361 aatttctctg gtaatatgta tttacctgtt tcaggatctt gctcaagctt ttgataaaag
     3421 gcaccctgct caagcgtctc ataaatagga gtatctaagg ctggcaagtt agcaaaatca
     3481 cccctaaagc cactaaatgg aatactcatc aattcttcct tagtgtctaa attgtctgtg
     3541 aaacggacaa agccttcaag gaagtagcca tttggcattg cttttaacaa ttcagcagcg
     3601 taagccttag cgtcaacaga aacttgaata tgctgctggt cctcggtgat attaatttcc
     3661 tgccactctg aatcctttaa tgcttttggc tgcaaggtga agtgaccatc tttagtttga
     3721 tcagtgatta ggttgacttg gaaataaagc tttttaggcc cttgattttt cgatagggca
     3781 ttaacattta gattaatgac aaattcatct gcaatgttcc ccagattgat tttagggttt
     3841 tgcttctgat cagtaaggta atagctggct gctagtgcct tttgaccatc tacctcacca
     3901 gcaccctgct ggcgtggaga aatataagcc ttgttttctg tgctataaag tgttcttgct
     3961 gagctcatca acacagctct aacaagctga gaaagctcct tatcagaaag ctctgggaat
     4021 ttctctttgt aagctttatg tagcatggcc acaagccctg acaccatagg tgttgacatg
     4081 cttgtaccag tcttgtaatc atattggtta ccatgaactg cagagtagac attgacacca
     4141 ggtgctgaaa tatctggctt gatacgacct tctgctgtca caccccagct ggattggctg
     4201 ataacgcggc caccagcatt gctaagcatt ttctcatagg ccttattaaa tctaaagctt
     4261 tgaccttcct taagagcttg agcgtccttg tagctcataa agccaacagg aatgtgagct
     4321 tcctttggaa tagaggcctt ttcaatcgta aagcttcctt caagcgcatt gttattgtag
     4381 ataatcacac cgctagcacc agctttaaca gcattttcaa tcttttgata aaagctaagt
     4441 gagccgccac gttcaatcaa agcaaccttg cctttaatat caagaccagt aaagtgagag
     4501 gcttcaccga atttggcatc agccacaaag taatcctgat cagcatcaaa tgagtcgccc
     4561 tctgacataa agatcgctag tttttgacta ccgtctgcgg tcttagcatt aacagactgg
     4621 ctaatagcgt aaacaggatt ggaagccgca acactgataa cctcttcaaa aatagctgga
     4681 ctattaaggg taccaaaatc aggatttgct gctagaggct ctcgagttcc cataccaact
     4741 gcactctcat taccagctcc agcaaccaac aaaacaccct tttcttgagc ataggctata
     4801 gcctttttaa cgtcctcatg aaccgttgat aaggaatccg ctgtttttcc aaagctcatg
     4861 ctaatcactg tagctcctag attaaccgcg tctgtgatcg ccttagcata ggattttgca
     4921 aattgatccc tttctggggc accagtcacc ttcatcagca taagagaagc atttggtgca
     4981 atcccctcaa cacgaaggcc atttcctgct ggtgttttcc cattacctgc tgctatagcg
     5041 gcagtatggt taccatgacc attatcagcg gtcaagccgc caatatcatc tgattgcttg
     5101 gtgtaatcgt aggcaaaaat aattttttcg ttgtaccact taccgtatgt gattttctga
     5161 tcctgctttt tagcaagaaa tgcctcttta gcaggaatag tatcgctatt ttttaagtcc
     5221 gaatcaagct taaaggcgtc atgctcagga tcaaaggaaa catcaataac agcaataacc
     5281 gctccgcttc ccttttgtgt ttactcttgt agggctttag cgttgaccga gtcattcagt
     5341 gataaattgg tcggtgctgt actctctggg ccttctgcaa aggctgatat ttctttttct
     5401 gttttagctt ctgtttctga agtcgcctgg ctgcttgaga attgtcatcc gtagcagtag
     5461 cttcaacagc tgcaactgga ttcacttgtg atacagaagc gtctaagtcc tgctgctcct
     5521 cagcaaatac agtctgacta tgaagcaata aaatacttgt tgtagccaat gttaactggc
     5581 ataataaact tttctttgag tgatattttt tagtcactaa taaaacctcc
//
LOCUS       DARYXS010000106         5616 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.107, whole genome shotgun sequence.
ACCESSION   DARYXS010000106 DARYXS010000000
VERSION     DARYXS010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5616
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.107"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            167..922
                     /locus_tag="TV193_001719"
     CDS             167..922
                     /locus_tag="TV193_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEL1513891.1"
                     /translation="MSQKEVGHQFLARLGKKRLRPGGVEATNWLVQQGEFSSDCKVLE
                     VACNRCTTSIELAQTYQCHITAVDLDTKVLAEARKAIEAAQMQDYIHLTQANALKLPF
                     ADNSFDIVINEAMLTMLNDAAKEKALKEYWRVLKPGGRLLTHDVSYEADETKAIIEQL
                     RDTINVNVSPLQLDAWRQLLVKSGFTAVNYSYGNMTLMSPLGMIKDEGVVAAIRIMLR
                     GMKKENRKQFLKMRHFFNKTGRKLCYIAAVSQK"
     gene            950..1288
                     /locus_tag="TV193_001720"
     CDS             950..1288
                     /locus_tag="TV193_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEL1513892.1"
                     /translation="MSLIRKIPTSTVIDLKAEVPIEEDQILSRTLVQRKDLGITLFSL
                     DKGQEIGRHSSLGDAMVNVLSGVVDITIGEACYEVAAGETIIMPANIPHSLFAKEAFQ
                     MLLVVVKPEA"
     gene            1290..1595
                     /locus_tag="TV193_001721"
     CDS             1290..1595
                     /locus_tag="TV193_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1513893.1"
                     /translation="MLADLLELVRYHDDQIASRSLHQSLGFKQSVVLYAMYQGETISN
                     ESSPEGKLLLVLEGRLLVSLTDQAHDMKAGGLISISAHQFYHLEAATNCKYLQIEMV"
     gene            2346..3083
                     /locus_tag="TV193_001722"
     CDS             2346..3083
                     /locus_tag="TV193_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1513894.1"
                     /translation="MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLL
                     ANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQ
                     VSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
                     IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRL
                     LYFKNGQSCMVSRLKMKALEASIKALH"
     gene            3456..3656
                     /locus_tag="TV193_001723"
     CDS             3456..3656
                     /locus_tag="TV193_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1513895.1"
                     /translation="MNTKTIEQFSTMTADMLAGVEGGWGYRWRCTDGYTSAWHLLRDT
                     AQENADNHMILYPGTVCRVYNA"
     gene            3723..4577
                     /locus_tag="TV193_001724"
     CDS             3723..4577
                     /locus_tag="TV193_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513896.1"
                     /translation="MLLILDNISKSYGSKKVLSRISAQFTPGLYGLLGANGTGKTTLL
                     NIISQFTVPDSGEISLNHQQQPKNFYQNIGFLPQQFNYYQQFSGLEFLLYMAALKNVK
                     RKKALVEADRLLKLVGLYDVRKKKIASYSGGMKQRLGIAQALINDPLLLILDEPTVGL
                     DPKERVKFRNIISDLSEQKIIILSTHIVSDVEAVAKEVILLKHGQFIEKGSVDQLVQT
                     MIGKVWEIPVATESAPAFLTDYAVVNEKIVKNNRILRVVSDESPCYQANPVSPTLEDL
                     YIYHFRKE"
     gene            4583..>5616
                     /locus_tag="TV193_001725"
     CDS             4583..>5616
                     /locus_tag="TV193_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513897.1"
                     /translation="MASLIPFEFKKLLRRQSVFGAIVVVLLAVGGLFYQHFFNGQISG
                     SSADQVHGRAAVAINQQIAEKHTGYLSDDLISRILNDYAKNQSDLKKKGVYSVVSHYA
                     ISHLVPKSTDKLIAINSTDKSLTFDNVHLKSREELGSALPLKELKLGNFAPWNQLFDV
                     TNSTYLLVVMLCLYITAPLFSGESSKKMNSILLTTVFGRGKLTLAKLAVSIAVSTLVF
                     AIASGLVFAVFATYFGFSGWDTSLQLNLYWIDPVINIMAFPEKMTLGIAFVYLLVFQY
                     IGLIFMTGIHALVSSLTKSPLTTFGISALIVYAPVFLMGIFPEGLMNKLLTFVSVQTF
                     GTQELLLKLA"
BASE COUNT         1705 a          919 c         1198 g         1794 t
ORIGIN      
        1 gccaattcta tgatttatca taaaaacaat catcagaaat gcttaagctt cattgaggat
       61 atgctttaag tgtgatatag ttgtagtaat catttattga tcaatttgtt aacagttagt
      121 ttattctaag tgatgatata tagcagagca aataggaggg catgtgatgt ctcaaaaaga
      181 agttggtcac cagtttttag ctcgactggg aaagaaacga ctacggcctg gcggtgttga
      241 ggcgacgaat tggctggttc agcaaggaga gttttcgagt gattgcaagg tcttggaagt
      301 ggcctgcaac cgttgcacga cctccattga gctggcgcag acttatcagt gtcatattac
      361 agcagtagat ttggatacca aggtactggc ggaggcaaga aaggctattg aggcagcaca
      421 aatgcaagac tatattcacc ttacccaagc taatgccttg aagctgcctt ttgcagataa
      481 tagctttgat atcgttatta acgaagctat gctaaccatg ttgaatgatg ctgcaaagga
      541 aaaagcactt aaggaatatt ggcgtgtttt aaagccgggt ggtcgcctac taacgcatga
      601 tgtttcctat gaagctgatg aaacaaaggc tattatagag caactaagag atacgattaa
      661 tgtgaacgta tcgccattgc agttagatgc ctggagacaa ttgctggtaa agagtggctt
      721 cacagcagtc aattactcct atggtaatat gacgctcatg tccccgcttg gcatgattaa
      781 agatgaaggg gttgtcgctg cgattcgtat tatgctgcgc ggcatgaaaa aagaaaatcg
      841 aaagcagttt ttaaagatgc gtcatttctt caacaaaact ggaagaaagc tgtgttatat
      901 tgccgctgta agtcaaaaat aactagaata atggtaaagg agaagtgaca tgtcattgat
      961 tcgtaaaatt ccaacaagca cagtcattga tttaaaggca gaagtgccaa ttgaagagga
     1021 tcaaatatta agtcgaacac tagttcaaag aaaagatttg ggcataaccc tgttttcatt
     1081 agataaagga caagaaatcg gtcgtcattc atcactggga gatgcaatgg ttaacgtgtt
     1141 aagtggagta gttgacatta ctattggaga agcctgttat gaggtagctg ctggcgagac
     1201 gatcatcatg cctgctaata ttcctcatag cttatttgct aaggaagcct tccagatgct
     1261 tttagttgtt gtaaagccgg aggcttagca tgttggctga tttattagaa ttagtaaggt
     1321 atcatgatga ccaaatagct agtcgttcgc ttcatcaaag cctaggcttt aagcaatctg
     1381 ttgttttata tgccatgtat cagggagaga cgattagtaa cgaatcaagc cctgaaggta
     1441 agctcctgct tgtcttagaa ggaaggttgc tggttagtct tacggatcag gctcatgaca
     1501 tgaaagcagg cggattgatc agtatctctg ctcatcagtt ttatcattta gaggctgcaa
     1561 caaattgtaa atacctgcaa attgaaatgg tctaaaagta tagagtgact ctcttgaatc
     1621 ttgcccccta ggctggtgtt ttagctgcct tagggggctt tttgtgttta gtgtcataag
     1681 gtttagctga agatctagct tacttcaaat cactcaaagt gattaataat aataacaatt
     1741 acctgttttg atgataaaaa gattgttttt atgataaaat aaatgacaga atatcccgga
     1801 tacctaatgt atttgttacc aataattcta gaaacttatt gcttggagaa ggtatagcta
     1861 caagcagcta atcatcagat agcctcagta acctgactag ccattgttag ttttccttat
     1921 ttaccattta agacataatc agtaccattt aagattttaa ctccctgctc cctagctttg
     1981 tgttagaatg tctgtgcaag gagatcagtg tgtggattga tagctgatga cttgtcaaac
     2041 aaaagtgata gtcgttaaga gctctctctc aaagaggtat gacttgcggc tcgtgctagt
     2101 atattatctg tggtaaaaaa attgtttgag gcgcgtgatt cgctaaggcc tattgaaaac
     2161 gctgcaatga caagttggtt agaagtcatt gacaaccttt agttaataag cttaacggtc
     2221 atggttttaa tggtgatgct aaaaagatac tgttcatgaa ggagagcgtt ctagctatca
     2281 cttgttcaaa aagctgcttt agtctcctaa aaaaacgata agctaaagca ataaggaggt
     2341 tctaaatgaa tatttttatt ctcgaagatg atctaggcca acagtttagg cttgagatga
     2401 agattcaaga gatattggat aagcatcact ggacttgtga tcgttttgaa gtttatggaa
     2461 agccctacca gcttctggca aatgttacag agagaggcag gcatcagctt ttctttctcg
     2521 atattcaaat tcgaaatgat gagaaaaagg gcttagctgt tgctcgtgag atcagaaagc
     2581 gtgaccctta tgccctcatt gtttttgtca ccacacattc tgagcttatg ccagtttctt
     2641 ttcgttatca ggtgtctgct ctagatttta tcgataagga attgtcaatg aaacatttct
     2701 cagataggat tgaaagagcc attatatatg cttatgaaga gcaagaaaat gtaacctcag
     2761 agggcttatt tatttttgca acggctaagg ctcaggtgca ggttcctttt tcaagcctat
     2821 tgttcattga gacctctagt actcctcaca agttgatttt gcattctcaa aacgagcgaa
     2881 tagaatttta tggctttctt tcagaggttc ttaagcaaga ttccagacta gtccaatgtc
     2941 atcgttctta tgttatcaat ccttacaatg tttcgtttct tgatcgtgat aagcgtttac
     3001 tctatttcaa gaatgggcag tcttgcatgg tttcaagact aaaaatgaaa gcacttgagg
     3061 cgtctattaa ggctttgcat tgacagtaaa agaatgccat gtggaagcca tcatttgttt
     3121 tttaatcaac ctcgttgata ccatttacct taagggatat ttattataaa tatatttagt
     3181 caaaactaag aaaaaggggt aacagttggt ttctaatgat gctcagagat atgatgtaca
     3241 tgcaaaaatc aattatatca taagaaaaga gagaaaaaga tatagctcgt gaaaggtatc
     3301 catatgatct taactggtaa tttcagaaga aaaattgacc attcacgaca aaataagaac
     3361 cattcaagat ttttgagtgt cgttgcttta aaaagcgcta cactaagttt gtcgagactg
     3421 tagctagata aaatcattat aaggaggtat tcgatatgaa tacaaaaaca attgaacaat
     3481 ttagtacaat gactgctgat atgcttgcag gcgttgaagg tggttggggt tataggtgga
     3541 gatgcactga tggttataca agtgcatggc atctattaag agatacagca caagaaaatg
     3601 ctgataacca catgattctt tatcctggta ccgtttgtcg agtatataat gcttaatggt
     3661 taatcatctg gggagcagcg aagtggtgct gttccctggg tttttactta ggaggaatga
     3721 caatgttgtt aatactagat aatatttcta aatcttatgg aagtaaaaag gtgttgagtc
     3781 gtatttctgc acaatttaca ccaggcttgt atgggttatt gggagcaaat gggaccggta
     3841 aaacgacttt attaaacatc attagtcagt ttacagttcc tgatagtgga gaaattagtt
     3901 taaatcatca acaacaacca aaaaactttt accagaatat tggcttttta cctcaacagt
     3961 ttaattatta tcagcagttt tccggtttag aattccttct ttatatggct gctttgaaga
     4021 atgttaaacg taaaaaggct ttagtagaag ctgatcggtt attaaagctg gtaggtcttt
     4081 atgatgttag aaaaaagaaa attgcttctt attctggcgg tatgaagcag cgattgggta
     4141 ttgctcaggc acttatcaac gatcctttac tgttaatttt agatgaacca acagtcggac
     4201 ttgatccaaa ggaacgtgta aaatttagaa atattatcag tgatttatca gagcaaaaaa
     4261 ttattatcct atcaacacat attgtatctg atgtagaagc ggttgcaaag gaggtaatcc
     4321 ttctaaagca tggtcagttt atagaaaaag gaagtgttga tcagttagtt caaacaatga
     4381 tcggcaaggt atgggagatt cctgttgcta cagagagtgc accagcattt ttgactgact
     4441 atgccgttgt caatgaaaaa attgtaaaaa ataatcgtat cttacgtgtt gtgagcgatg
     4501 agagtccttg ttatcaggca aatcctgtgt caccaacatt agaggatctc tacatttatc
     4561 attttagaaa ggagtgaatt ctatggcatc tctcataccc tttgagttta aaaaattatt
     4621 aagacgacag tcggtatttg gtgcgattgt agtggtctta ttggctgtag gtggtctttt
     4681 ttaccagcat ttttttaacg gtcagatcag tggctcttct gcagatcagg ttcatggacg
     4741 tgcagctgta gcaattaacc aacaaattgc tgagaagcat acaggttatt tatctgacga
     4801 tctgattagt cgtatcctca atgattatgc taaaaatcaa tcagacctaa aaaagaaggg
     4861 tgtatatagt gtggtatcac attatgctat ctctcattta gtgcctaagt ctactgataa
     4921 gcttatcgct attaatagca ctgataagtc tctgacattt gacaatgttc atctcaaatc
     4981 acgtgaagag ttggggtccg ctctgccttt gaaagagttg aagttaggta attttgctcc
     5041 ttggaatcag ttgtttgatg taaccaatag tacttatctt cttgttgtta tgctttgtct
     5101 ttatataacg gctcctttat tttcagggga atcatctaaa aagatgaact ctatcttatt
     5161 gacgactgtt tttggacgtg gtaaattgac tcttgctaaa ttagcagtta gcatagctgt
     5221 cagtactttg gtatttgcaa ttgctagtgg tctggtcttt gctgtctttg cgacctattt
     5281 tggttttagc ggctgggaca ctagcttaca actcaatttg tattggattg atccagtgat
     5341 aaacattatg gctttcccgg aaaagatgac cttaggcatt gcgtttgtct atttattggt
     5401 gtttcagtat attggcctga tatttatgac aggcattcat gcactagttt catctctaac
     5461 taagtctcct ctaaccactt ttggtatatc tgctcttatt gtatatgcac cggtctttct
     5521 aatgggaatt tttccagaag gtttgatgaa caaactgtta acatttgtat ccgtacaaac
     5581 ctttggtaca caagaattat tattaaaatt ggccta
//
LOCUS       DARYXS010000107         5331 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.108, whole genome shotgun sequence.
ACCESSION   DARYXS010000107 DARYXS010000000
VERSION     DARYXS010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5331
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.108"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            90..1643
                     /locus_tag="TV193_001726"
     rRNA            90..1643
                     /locus_tag="TV193_001726"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1865..1937
                     /locus_tag="TV193_001727"
     tRNA            1865..1937
                     /locus_tag="TV193_001727"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1898..1900,aa:Ala,seq:tgc)
     gene            2245..5144
                     /locus_tag="TV193_001728"
     rRNA            2245..5144
                     /locus_tag="TV193_001728"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5229..>5331
                     /gene="rrf"
                     /locus_tag="TV193_001729"
     rRNA            5229..>5331
                     /gene="rrf"
                     /locus_tag="TV193_001729"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1525 a         1083 c         1543 g         1180 t
ORIGIN      
        1 aagacgacct aaacgtgcgg gttacggaag taacctgtca ataaagaaac aagtcagtaa
       61 tgacgtcgag ttaagagctc aaacactgaa ttaacgagag tttgatcctg gctcaggacg
      121 aacgctggcg gcgtgcctaa tacatgcaag tggaacgcac agatgatacg tagcttgcta
      181 caattatctg tgagtcgcga acgggtgagt aacgcgtagg taacctagct tatagcgggg
      241 gataactatt ggaaacgata gctaataccg cataaaagtg gttgacccat gttaaccatt
      301 taaaaggagc aacagctcca ctatgagatg gacctgcgtt gtattagcta gttggtaggg
      361 taaaggccta ccaaggcgac gatacatagc cgacctgaga gggtgaacgg ccacactggg
      421 actgagacac ggcccagact cctacgggag gcagcagtag ggaatcttcg gcaatggggg
      481 gaaccctgac cgagcaacgc cgcgtgagtg aagaaggttt tcggatcgta aagctctgtt
      541 gttagagaag aacagtgatg ggagtggaaa gtccatcatg tgacggtaac taaccagaaa
      601 gggacggcta actacgtgcc agcagccgcg gtaatacgta ggtcccgagc gttgtccgga
      661 tttattgggc gtaaagcgag cgcaggcggt ttgataagtc tgaagttaaa ggcagtggct
      721 taaccattgt atgctttgga aactgttaaa cttgagtgca gaaggggaga gtggaattcc
      781 atgtgtagcg gtgaaatgcg tagatatatg gaggaacacc ggtggcgaaa gcggctctct
      841 ggtctgtaac tgacgctgag gctcgaaagc gtggggagca aacaggatta gataccctgg
      901 tagtccacgc cgtaaacgct gagtgctagg tgttaggccc tttccggggc ttagtgccgg
      961 agctaacgca ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa
     1021 ttgacggggg cccgcacaag cggtggagca tgtggtttaa ttcgaagcaa cgcgaagaac
     1081 cttaccaggt cttgacatcc cgatgctatt cttagagata agaagttact tcggtacatt
     1141 ggagacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg
     1201 caacgagcgc aacccttatt gttagttgcc atcattaagt tgggcactct agcgagactg
     1261 ccggtaataa accggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgacctg
     1321 ggctacacac gtgctacaat ggttggtaca acgagtcgca agccggtgac ggcaagctaa
     1381 tctctgaaag ccaatctcag ttcggattgt aggctgcaac tcgcctacat gaagtcggaa
     1441 tcgctagtaa tcgcggatca gcacgccgcg gtgaatacgt tcccgggcct tgtacacacc
     1501 gcccgtcaca ccacgagagt ttgtaacacc cgaagtcggt gaggtaaccg ttaaggagcc
     1561 agccgcctaa ggtgggatag atgattgggg tgaagtcgta acaaggtagc cgtatcggaa
     1621 ggtgcggctg gatcacctcc tttctaagga aaaaggaagc acgtttagcg tcttatttag
     1681 ttttgagagg tcttgaaata agtcatgaga acgttaagaa acccgtatga caatagggaa
     1741 ctgacgcaga gtcgtaggac tcaaggaagt gattcttttt cactagggtt ttagttcgaa
     1801 tacagtttgg cttcatacag accattgata agagtataca tatacaagta catttatagt
     1861 gtacggggcc ttagctcagc tgggagagcg cctgctttgc acgcaggagg tcagcggttc
     1921 gatcccgcta ggctccatta tctaggatac aaagagaagt ttgggttacc taattttctg
     1981 tattctaaga tatataagat atagttcaag taattgaaca cgacctcatt ttttaggaaa
     2041 aaagataaat ctcctcgtgt gtaaagcaca catcgtcgat ttcctatttt tctacaaaaa
     2101 tgcccaacaa gttgggacgg tcttagtatc ttaatcttgt ccattgaaaa ttgaataact
     2161 atatcatatt ccgcaatcaa aaaagattgt aagaaagtaa caagaaataa accgaaacgc
     2221 tgtgataacg agtttaaaaa ataaggttaa gttaataagg gcgcacggtg gatgccttgg
     2281 cactagaagc cgaagaagga cgtgacaaac gacgaaatgc tttggggagc tgtaagtaag
     2341 caaagatcca gagatgtccg aatgggggaa cccactagct aatggctagt atccataact
     2401 gttaaggtta tgagaaggaa gacgcagtga actgaaacat ctaagtagct gcaggaagag
     2461 aaagcaaacg cgattgcctg agtagcggcg agcgaaaagg caggagggca aaccgaagag
     2521 tttactcttc ggggttgtag gactgcgctg tgggacgaca agattataga agaaggcctt
     2581 gggaagggtc gccaaagaga gtaatagcct cgtattcgaa atagtcttta accctagcag
     2641 tatcctgagt acggcgagac acgaggaatc tcgtcggaat ctgggaggac catctcctaa
     2701 ccctaaatac tcactagtga ccgatagtga accagtaccg tgagggaaag gtgaaaagca
     2761 ccccgggagg ggagtgaaag agaacctgaa accgtgtgcc tacaagaagt tcgagcccgt
     2821 taatgggtga gagcgtgcct tttgtagaat gaaccggcga gttacgttta tgtgcgaggt
     2881 taagttgaag agacggagcc gaagggaaac cgagtcttaa tagggcgtaa gtacgtggac
     2941 gtagacccga aaccatgtga cctacccatg agcaggttga aggtgcggta agacgcactg
     3001 gaggaccgaa ccagggcacg ttgaaaagtg cttggatgac ttgtgggtag cggagaaatt
     3061 ccaaacgaac ttggagatag ctggttctct ccgaaatagc tttagggcta gcgtcgatat
     3121 gaagtctctt ggaggtagag cactgtttgg gtgaggggtc catcccggat taccaatctc
     3181 agataaactc cgaatgccaa tgagatatga tcggcagtca gactgcgagt gctaagatcc
     3241 gtagtcgaaa gggaaacagc ccagaccacc agctaaggtc cccaaataac tgttaagtgg
     3301 aaaaggatgt ggggttgcac agacaactag gatgttagct tagaagcagc tattcattca
     3361 aagagtgcgt aatagctcac tagtcgagtg accctgcgcc gaaaatgtac cggggctaaa
     3421 acagtttacc gaagctgtgg attaccgtta aggtaatggt aggagagcgt tctatgtgtg
     3481 atgaaggtat actgtgaaga gtgctggaac gcatagaagt gagaatgccg gtatgagtag
     3541 cgaaagacag gtgagaatcc tgtccaccgt aagactaagg attccagggg aaggctcgtc
     3601 cgccctgggt tagtcgggac ctaaggagag accgaagggt gtatccgatg gacaacaggt
     3661 tgatattcct gtactagagt atatagtgat ggagggacgc agtaggctaa ctaaaccgga
     3721 cgactggaag agtccggcta agcagtgagg tgtgatgtga gtcaaatgct tacatctata
     3781 acattgagct gtgaagggga gcgaagttaa gtagcgaagt tagagacgtc acactgccaa
     3841 gaaaagcttc tagcgatacg tatactctac ccgtaccgca aaccgacaca ggtagtcgag
     3901 gcgagtagcc tcaggtgatc gagagaactc tcgttaagga actcggcaaa atggccccgt
     3961 aacttcggga gaaggggcgc tgactgaagg tcagccgcag tgaataggcc caagcaactg
     4021 tttatcaaaa acacagctct ctgctaaatc gtaagatgat gtataggggg tgacgcctgc
     4081 ccggtgctgg aaggttaaga ggagtgctta gcgcaagcga aggtatgaat tgaagcccca
     4141 gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt cgggtaagtt
     4201 ccgacccgca cgaaaggcgt aatgatttgg gcactgtctc aacgagagac tcggtgaaat
     4261 tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc atggagcttt
     4321 actgcagttt gatattgagt atctgtacca catgtacagg ataggtagga gccatagaag
     4381 tcgggacgcc agtttcgatg gaggcgatgt tgggatacta cccttgtgtt atggctactc
     4441 taacccggat aggtgatccc tatcggagac agtgtctgac gggcagtttg actggggcgg
     4501 tcgcctccta aaatgtaacg gaggcgccca aaggttccct cagattggtt ggaaatcaat
     4561 cgcagagtgt aaaggtataa gggagcttga ctgcgagagc aacacctcga gcagggacga
     4621 aagtcgggct tagtgatccg gtggtaccgt atggaagggc catcgctcaa cggataaaag
     4681 ctaccctggg gataacaggc ttatctcccc caagagttca catcgacggg gaggtttggc
     4741 acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt tgggctgttc
     4801 gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc ggtccctatc
     4861 cgtcgcgggc gtaggaaatt tgagaggatc tgctcctagt acgagaggac cagagtggac
     4921 ttaccgctgg tgtaccagtt gtctcgccag aggcatagct gggtagctat gtagggaagg
     4981 gataagcgct gaaagcatct aagtgcgaag ccctcctcaa gatgagattt cccataacgt
     5041 taagttagta agagccctga gagatgatca ggtagatagg ttaggagtgg acgtgtggtg
     5101 acacatggag cggactaata ctaatagctc gaggacttat ccaaaagatg aaaccagtcg
     5161 ctattgacag cttaaggaat tcttgttaga ctatagttat tcaattttga gtggagaaga
     5221 ctcgtaagtt aagtgacgat agcctaggag atacacctgt acccatgccg aacacagtag
     5281 ttaagcccta gaacgcctga agtagttggg ggttgccccc tgtgagatac g
//
LOCUS       DARYXS010000108         5304 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.109, whole genome shotgun sequence.
ACCESSION   DARYXS010000108 DARYXS010000000
VERSION     DARYXS010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5304
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.109"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            88..816
                     /locus_tag="TV193_001730"
                     /pseudo
     CDS             88..816
                     /locus_tag="TV193_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            809..2341
                     /locus_tag="TV193_001731"
                     /pseudo
     CDS             809..2341
                     /locus_tag="TV193_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_028398951.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
     gene            2699..3682
                     /gene="guaC"
                     /locus_tag="TV193_001732"
     CDS             2699..3682
                     /gene="guaC"
                     /locus_tag="TV193_001732"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEL1513898.1"
                     /translation="MFNDMPVFDYEDIQLIPNKCIINSRSEADTSVRLGNYTFKLPVI
                     PANMQTIIDETIAEQLARDGYFYIMHRFDEEGRKPFIQRMHEQQLIASISVGVKDYEY
                     DFVSSLKEDAPEFITIDIAHGHADSVIKMIKHIKAELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGATMVMIGSLFAGHIESPGKMVEIDGQSFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLADTLTEMKQDLQSSISYAGGRDLESLRRVNYVIVKNSIWNGDSI"
     gene            3868..4449
                     /locus_tag="TV193_001733"
     CDS             3868..4449
                     /locus_tag="TV193_001733"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEL1513899.1"
                     /translation="MRLLEERILADGTVLGETILKVDQFLTHQVDYRLMKEIGRVFAD
                     QYADLGITKVVTIEASGIAPAVYTAEALEVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGGLLSKEDRVLIIDDFLANGQAAKGLIDIIHQAGAKAVGIGIVIEKSFQA
                     GRQLLEDLGVEVTSLARIKHFDNGIVSFLEADA"
     gene            complement(4737..>5304)
                     /locus_tag="TV193_001734"
     CDS             complement(4737..>5304)
                     /locus_tag="TV193_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1513900.1"
                     /translation="LDQSLGSIFLKEKGMSIDLGALAKGYIADKLMAFLIKDGITAAL
                     INLGGNVLVHGTNKQRHNGLFYVGIQQTNQKRGQHVGVIKVNNKSVVTSGIGERQLQI
                     KDKTYHHLLDPHNGYPIKTNMASLTIVSQFSLDGELWSSRLFGLEHSFVLSQLNKLPE
                     VEGIIITKDGQVTISDGLKGAFRLHYKH"
BASE COUNT         1511 a          973 c         1235 g         1585 t
ORIGIN      
        1 gaggcttagc ctaagctgct gagcttatct gataatcatt cttcttagca ctgagataac
       61 cccctttatc gattaattgg agaatctatg atacgtttta ataatgtttc caaaaccttt
      121 ggtcacacca aggtgctgca ggagcaaagt tttcaaatac agaatcgcga attttttgtg
      181 ctggtcggtc caagcggctc tggcaaaaca aagctcttaa aaatgatcaa ttgccttact
      241 gaaccaagct ctggcgaaat tctattaaac ggaaggccac aaaaagagct agatttgcga
      301 gatatgcgct tatctattgg ctatgttctt cagcaaattg ccctgtttcc aaaccttaca
      361 gttgctgaaa atatcgctat tattccagag atgaagaagt ggtcagacaa agagattaga
      421 actaagacag aggaattgtt agataaggtt ggattgcctg caagggatta tctaaatcgc
      481 tatcccagtg atttatccgg tggagagcag cagaggattg gtattgttcg tgccatcatt
      541 tctcacccca aggtgctgtt aatggacgag ccgttttcag ccttggatcc tatttcacgc
      601 aagtaattac aggacttgat gttaagtctt cacaaggagt ttgatatgac aattgtcttt
      661 gttactcatg atattgatga ggctatcaag cttggagatc gtgtggctgt tttaaatgaa
      721 gggcaaattg ttcaactgga tcgaccagat gcgatcatag ctgcgcctgc taatgatttt
      781 gtagcaagtc tatttggagg tcgtgattat gcctagttta ctgatgacct tttgggatcg
      841 ttttggtgat tgggcaaggg cattaggaga gcacttgcag atttctcttc tttctttgct
      901 ggctgccttg ctgataggca ttccgcttgc agctctgttg agtaaaagta agcgctggtc
      961 aaatatcatc ttgcagctga caggtgtttt tcaaaccatt ccttccctag ccttgttggg
     1021 actatttatc cctctaatgg gaatcggaac tgctccagct gtaacagctt tggttattta
     1081 tgccatattt cctattttac aaaatacgat tactggctta aatgctattg atccaagtct
     1141 tgtagaggcc ggaacagcct ttggaatgac caagtgggag cgactgaaaa tatttgaaat
     1201 tcctattgct atgccagtta ttatgtcagg tgttcggacc tcagcagtga tgattattgg
     1261 aacagccacc ctagcttctt tgatcggagc tggcggctta gggaccttta tcctattagg
     1321 aattgaccgt aataatgctc agctgattgt gattggtgct gtgtcgtcag ccttgcttgc
     1381 gatagtgttt aacagtcttt tgtgatacct tgagaaggcc tcactgaggc gtattgcgat
     1441 aagctttgct gcgaccttat tactgctctt aatttcctat actccaatgt ttgtcaagcg
     1501 gtttgttaat cagtcaaata ctctggtgat tgctggcaag ctaggagtag agccggatat
     1561 tttgatcaat atctataaag agctgattga agaccagtcc aagcttaagg ttgaattgaa
     1621 acctaatttt ggcaagacaa gctttttata cgaggcgatt aaatcaggag atattgatat
     1681 ttatccagaa tttacaggaa ccatcacctc tagcctatta aagaaaaagc ctaagctttc
     1741 taatgaccct aatcaggttt acttagctgc taaggagggg attgctgagc aggatcagtt
     1801 gacgctttta aagccctttg cctatcaaaa tacctatgca gtggcgatgc ctgaaaaaat
     1861 agctgacgaa tttaacattc aaagtatttc agatgtgaag aaatatgaaa aacagctaaa
     1921 ggctggtttt acactagaat ttaaggatag agaggacggc tataagggca tacaggataa
     1981 gtatgatcta catttatcag ttgcaacgat ggagccagct cttaggtacc aagccattca
     2041 gtcaggaaac attcagctga cagacgctta ttcaactgat gctgagatcg tgaaatatca
     2101 gcttcgagtc ttaaaggacg ataagcagct ctttccacct tatcaaggag cgccattgat
     2161 gaaggcttcc ttactaagaa agcaccctca tctcaaaacg attctcaatc agttatcagg
     2221 aaagattact gaagaggaga tgcaagcaat gaactatgag gtgtccgtaa agggcagagc
     2281 agctagcctt gtggcacatg actaccttgt aaaggccggt cttattgcaa gaaccaaata
     2341 agcaggcatg ctagtcttat tctggactgg catgctttat ttatgtgatt tttagtctgt
     2401 ctggctctgc aaggtgtgtg ccaaataacc gctcgtttga tgtgtggtta ttgatttagt
     2461 agctaaggat tggaatctta aaataaaatc cgaacgtttg tctaaaaaaa gctttaaaaa
     2521 ttgacaaaac ataaacgaaa ggataaaata aattaaggaa aggtaacatt ttacctagcg
     2581 atgcctcgga caagcttgag gtcataggaa ggtcatttta tatagaagct tatgtcagct
     2641 gcagatcagg gaagtccttg ctggattagt agctgaatgt tgaaaaagga gagaaatgat
     2701 gtttaatgac atgcctgtat ttgattatga ggatattcaa ttaattccta acaaatgtat
     2761 catcaatagt cgttcagaag cagatacgag tgtaagactt ggtaattata cctttaagct
     2821 acctgttatt cccgccaaca tgcaaaccat tattgacgaa acaattgcag agcagttggc
     2881 aagagatggt tatttctata ttatgcaccg ctttgatgag gaggggcgca agccctttat
     2941 ccagcgtatg catgagcaac agctcatcgc ctctatttcg gttggtgtaa aggattatga
     3001 atacgatttc gtctcttctt tgaaggagga cgcacctgag tttatcacga ttgatattgc
     3061 tcatggccat gctgatagtg tgatcaaaat gattaagcat attaaggctg agctgcctga
     3121 gacctttgtt atagctggaa atgtcggaac accagaggct gttcgagagc tcgaaaatgc
     3181 tggtgctgac gcaacaaagg tcgggattgg gcctggtaag gtttgtatca caaaggttaa
     3241 gacaggcttt ggaacagggg ggtggcaatt agctgctgta cgttggtgtg ctaaggctgc
     3301 tcgtaagccg attattgctg atggcggtat tcgtactcat ggtgatattg ccaagtcgat
     3361 tcgatttggg gcaacaatgg tgatgatcgg ttcactcttt gcaggtcata ttgaaagccc
     3421 aggcaagatg gtagaaatcg acggacagtc cttcaaggaa tattatggct ctgcctctga
     3481 atatcaaaaa ggggagcata aaaatgtcga aggcaagaag attttgcttc caaccaaggg
     3541 tcatctagct gatactttaa ccgaaatgaa gcaggattta cagtcatcaa tctcatatgc
     3601 tggaggcaga gatttggaga gcctgcgtcg tgtgaattat gttatcgtga aaaattctat
     3661 ttggaatggt gactctattt aaagccttgg ctaaagacct agtctaaata aggataagca
     3721 agctgattga tgctgagaat aagcacagcg tgtctatagg acgcctgaat gtctagtagc
     3781 cagtaaagct tttaggcttg ctgattggat aggtcattgt gcctatgtgc agcagggctc
     3841 tagggactta gataaaaagg agacatgatg aggttactgg aggagcgtat cctagctgat
     3901 ggaactgttt taggtgagac gattttgaag gtggatcaat ttttaacaca tcaggttgac
     3961 tatcgcttga tgaaggaaat cggtagagta tttgctgatc aatatgctga tttgggcatt
     4021 accaaggtgg tcaccattga agcctctggt atcgcaccag cagtttatac cgcagaagct
     4081 cttgaggttc cgatgatttt tgccaaaaag cacaaaaata tcacgatgac agagggaatt
     4141 ttaacagcag aggtttattc ctttaccaaa caagtgacaa gtactgtttc tattgcagga
     4201 ggactgctat caaaagaaga tagggttttg attattgatg actttttggc taatggtcaa
     4261 gcggcaaaag gcttgattga tatcattcat caagcagggg ccaaagctgt tggcataggc
     4321 attgtcattg aaaaatcttt tcaggctgga cggcaattgc ttgaggattt gggagtagag
     4381 gtcacttcat tggctcgtat taagcatttt gacaatggaa tagtaagctt tttggaggct
     4441 gatgcctgat gactgcttct tatctctcag cattaagctt tttacttgta tagctatacc
     4501 agctttattt cagtagctat tggctggtga taagggatat tggtatggcg gtgcattacg
     4561 gcgagccgtg ggcagttgcc cttgcggctt tacgatttag tatagactat caagaattga
     4621 ctgcttcctt tttatcgaga tgaatcatta gacagacaat catgatttgg cgtgaaggct
     4681 gctttcagta aacattacat catcaaaaat cagctaggta ttcacttagc tgatttttag
     4741 tgcttataat gtagccgaaa ggctcccttt aacccgtctg agatagtaac ctgaccatct
     4801 ttggtaatga taatgccttc cacctcaggc agcttattta gctgacttag gacaaaggaa
     4861 tgctctaagc caaaaagacg actactccat agctcaccat caagtgagaa ttggctgaca
     4921 atggttaggc tagccatatt ggtcttgata ggatagccgt tgtgaggatc aagaaggtga
     4981 tgataagttt tgtctttgat ttgtaattgt ctctcgccga ttcctgaggt tactacagat
     5041 ttattgttaa ccttaatcac gccgacatgc tgtcctcttt tttgattggt ctgctggatc
     5101 ccaacgtaaa acaagccatt atgtcgttgc ttgttggtgc catgcacaag gacatttcca
     5161 cctagattga taagagcagc agtgataccg tctttaataa gaaatgccat gagcttatca
     5221 gcaatatagc cctttgctag ggcacctaag tcgatagaca tgcccttttc tttcaaaaaa
     5281 atacttccaa ggctttgatc taag
//
LOCUS       DARYXS010000109         5180 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.110, whole genome shotgun sequence.
ACCESSION   DARYXS010000109 DARYXS010000000
VERSION     DARYXS010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5180
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.110"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..1216
                     /gene="secY"
                     /locus_tag="TV193_001735"
     CDS             <1..1216
                     /gene="secY"
                     /locus_tag="TV193_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEL1513901.1"
                     /translation="IGTHITVPGVNAKSLEQLSELPFLNMLNLVSGNAMRNFSVFSMG
                     VSPYITASIVVQLLQMDILPKFVEWGKQGEVGRRKLNQATRYISLVLAFAQSIGITAG
                     FNTLSSVALVKTPDVRTYLLIGALLTTGSVIVTWLGEQITDKGFGNGVSMIIFAGIIS
                     SIPNAIATIREDYFVNVKSGDLQSSYIVVGILILAVLAIVFFTTYVQQAEYKIPIQYT
                     KLVQGAPTSSYLPLKVNPAGVIPVIFASSITTIPSTIIPFFQNGRDIPWLTTLQGIFN
                     YQSPTGMIVYALLIILFSFFYTFVQVNPEKTAENLQKNSSYIPSVRPGRETEEFMSSL
                     LKKLATVGAIFLAFISLVPIAAQQALNLSSSIALGGTSLLILISTGIEGMKQLEGYLL
                     KRKYVGFMNITE"
     gene            1368..2009
                     /locus_tag="TV193_001736"
     CDS             1368..2009
                     /locus_tag="TV193_001736"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEL1513902.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLK
                     ALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDD
                     KPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            2127..2345
                     /gene="infA"
                     /locus_tag="TV193_001737"
     CDS             2127..2345
                     /gene="infA"
                     /locus_tag="TV193_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEL1513903.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            2371..2487
                     /gene="rpmJ"
                     /locus_tag="TV193_001738"
     CDS             2371..2487
                     /gene="rpmJ"
                     /locus_tag="TV193_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEL1513904.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            2505..2870
                     /gene="rpsM"
                     /locus_tag="TV193_001739"
     CDS             2505..2870
                     /gene="rpsM"
                     /locus_tag="TV193_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEL1513905.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            2888..3271
                     /gene="rpsK"
                     /locus_tag="TV193_001740"
     CDS             2888..3271
                     /gene="rpsK"
                     /locus_tag="TV193_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEL1513906.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            3318..4256
                     /locus_tag="TV193_001741"
     CDS             3318..4256
                     /locus_tag="TV193_001741"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEL1513907.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            4271..4657
                     /gene="rplQ"
                     /locus_tag="TV193_001742"
     CDS             4271..4657
                     /gene="rplQ"
                     /locus_tag="TV193_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEL1513908.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(4875..5118)
                     /locus_tag="TV193_001743"
                     /pseudo
     CDS             complement(4875..5118)
                     /locus_tag="TV193_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1584 a          929 c         1122 g         1545 t
ORIGIN      
        1 tattggaaca catatcactg ttcctggtgt aaatgcaaaa agcttagagc agctgagtga
       61 gcttcccttc ctaaatatgt tgaacttggt cagcggtaat gcaatgagaa acttttcagt
      121 tttctcaatg ggtgttagtc cctatattac agcctcaatc gttgttcagc tattgcagat
      181 ggatattttg ccgaagtttg ttgagtgggg aaaacaaggt gaggttggcc gtcgtaagct
      241 aaaccaagcg acgcgctata tttcccttgt cttagccttt gctcaatcta tcggtattac
      301 agcgggtttt aacaccttat caagtgtggc cctagtcaaa acaccagatg taagaaccta
      361 tttactgatt ggagctttac tgacaacagg tagtgtgatt gtgacctggc ttggtgaaca
      421 gattaccgat aaaggctttg gtaatggggt gtctatgatt atctttgcag gtatcatttc
      481 ctctattcca aatgctattg caaccattcg tgaggattat tttgtcaatg tgaagtcagg
      541 tgacctacag tcatcttata tcgttgttgg tattctcatt cttgcagtgc ttgctatcgt
      601 ctttttcaca acgtatgttc agcaggcgga atataaaatt ccaatccaat atacaaagct
      661 tgttcagggt gcgcctacaa gctcatacct tcccttaaaa gtaaatccag ctggtgttat
      721 tcccgttatc tttgccagct cgattacaac aattccaagt acgattatcc cgttctttca
      781 aaatggcaga gatattccat ggttgacaac tttgcaagga atttttaact atcaatctcc
      841 aacaggaatg attgtttatg ccttgttaat tatcctgttt tcattcttct atacctttgt
      901 tcaagtaaat cctgagaaaa cagctgaaaa tctacagaag aattcgtcct atattccaag
      961 tgttagacct ggacgagaaa cagaagaatt tatgtcatcc ttgctaaaga aattggcaac
     1021 tgtgggtgct atcttcctag catttatatc tcttgttcca attgcggcac aacaagctct
     1081 taacctatct tctagtattg cattaggtgg aactagcttg ctgattttga tttcgacagg
     1141 tatcgaaggt atgaagcagc ttgaaggtta ccttctcaag agaaaatatg tcggatttat
     1201 gaatattaca gaatagaata tgggttgaca ctgtcaacct tctattttgt ttttaaatga
     1261 caataagatt tacagagcct tggttcctat cttcttattg ccatttgaaa acaaaaacaa
     1321 ggaaaactaa atttcctatt atctttatgt caaaagagga gaaaaagatg aatcttttaa
     1381 tcatgggctt acctggtgcc ggtaagggta cacaggctgc aaagattgtt gaaacctttg
     1441 agcttattca tatttcaaca ggagatatgt tccgcgctgc aatggctaat cagactgaaa
     1501 tgggagttct tgcgaaatct tatatcgata agggtgattt ggtgccagat gaggtaacca
     1561 atggtatcgt taaagaacgc ttagcacaag ctgatattaa agaaaaggga tttcttttag
     1621 atggctatcc tcgtaccatt gagcaggcac atgccttaga tgaaacctta aaagcattgg
     1681 gacttacgtt agatggtgtg atcaacattg aggttgaccc tgcgtcactc attgacaggc
     1741 ttagcggtcg tatcatcaac aaaaaaacag gggaaacctt ccataagatc tttaacccac
     1801 cagtgggaga ctataaggaa gaggactttt atcaacgtga agatgataag cctgaaacag
     1861 ttaagcgtcg cttagatgtt aatattgcac aaggtgagcc tattatcaag cattatcgtc
     1921 aagcaggcat tgttcgtgac attgacggaa acaaggacat ttctgaggtc tttgctgaca
     1981 taaaaaaggt catcgaaaac ctgaaataaa ttccagaaaa tcgcttgcga aagtgatttt
     2041 atcgtgatat actagactag tctgacttat aattgttacc tctgtgctca gaggacatca
     2101 aatcgaaatt tagggggtac ttttgcgtgg caaaagaaga cgtgattgaa attgaaggta
     2161 aagttgtcga aactatgcca aatgcaatgt ttactgttga attggaaaat ggacatcaga
     2221 ttttagcaac cgtatcagga aagatccgca aaaattacat tcgtatttta gtgggtgatc
     2281 gtgttactgt agagatgagt ccttacgact tgacacgtgg acgtatcaca taccgcttta
     2341 aatagtcgaa ataattggag ggattaaaac atgaaggtaa gaccatcggt taaaccaatt
     2401 tgcgaatact gcaaggttat tcgtcgtaac ggtcgtgtta tggtaatttg tccgacaaat
     2461 ccaaaacaca agcaacgtca aggataagat agaaaggaga aaaaatggct cgtattgctg
     2521 gagttgatat tccaaatgat aagcgtgtag taatttcact tacctatgtg tatggaattg
     2581 gtcttgcaac atctaaaaaa atcttagcag cagcaggtgt ctctgaggac attcgtgtta
     2641 aagatttgac atcagatcaa gaagacgcta tccgtcgcga agtggataca attaaagttg
     2701 aaggtgatct tcgtcgtgaa gtaaacctaa atatcaagcg tttgatggaa atcggttcat
     2761 atcgtggaat tcgtcaccgt cgtggacttc ctgtacgtgg acaaaacaca aaaaacaatg
     2821 ctcgtactcg taaaggtaaa gctgttgcga ttgcaggtaa gaaaaaataa aataggaggt
     2881 aaaaaaattg gctaaaccaa cacgtaagcg tcgtgtgaaa aagaacatcg aatctggtgt
     2941 tgcacatatt cacgctacat ttaataacac tattgttatg attacagatg tgcacggtaa
     3001 tgctttagca tggtcatcag ccggtgctct tggttttaag ggttctcgta agtcaactcc
     3061 ttttgctgct caaatggctg cagaggctgc tgcgaaatct gcacaagaac atggtttaaa
     3121 aactgttgaa gttactgtaa aaggtcctgg ttcaggtcgt gaatcagcta ttcgtgccct
     3181 agctgctgcc ggtcttgaag taactgccat tcgtgatgtg actcctgtac cgcataatgg
     3241 tgctcgtcct ccaaaacgtc gtcgtgtata atcacagtaa caaatagtac acaagtttcg
     3301 tttcgagggg tgaaagaatg attgagtttg aaaaaccaat aataacaaaa attgatgaaa
     3361 ataaagatta cggtagattt gtaatcgaac cacttgaacg tggatatggt acaactctag
     3421 gtaattcact tcgtcgtgta ctcttgtctt cacttccagg tgcagctgtt acatcaatca
     3481 gaattgatgg agtactacac gaatttgata caatcccagg tgtacgtgaa gatgtcatgc
     3541 aaattatcct taatgttaag ggacttgctg tgaaatcata cgtcgaagac gaaaagatta
     3601 tcgagcttga tgtagaaggt ccagcagagg taacagctgg agatattctc acagatagcg
     3661 atatcgaact tgttaaccct gatcattatc tttttactat tgctgatggt tatacattga
     3721 aggcttcaat gactgtcgct aaaaaacgcg gctatgtacc agcagagggt aataaaaaag
     3781 atgatgcacc tgtggggacg ttggcagtag attcaatcta tacgccagta aaaaaggtta
     3841 attatcaagt tgagcctgct cgtgtaggta gtaatgacgg ctttgataaa ttgactattg
     3901 aaatcatgac aaacggaaca attattcccg aagatgcctt aggtttatct gctcgagttt
     3961 taatcgaaca cttgaattta tttactgatt taacagatgt tgcaaaggca actgaagtga
     4021 tgaaggaagc tgaaaaagtg aacgatgaaa aggtacttga tcgcactatt gaggaacttg
     4081 atttgtccgt acgctcatat aactgcttga aacgtgccgg tattaatact gtcttcgatt
     4141 taacagaaaa atctgagcct gaaatgatga aggtccgtaa ccttggacgt aagagtcttg
     4201 aggaagtaaa ggtcaagctt gctgacttag gtttgggact aaaaaacgat aaataacata
     4261 ggaggataaa atggcttacc gtaaactagg acgcactagc tcacaacgta aagcaatgct
     4321 tcgtgactta acgacagatc ttttgattaa cgaatcaatt gtaacgacag aagcacgtgc
     4381 aaaggaaatc cgtaaaacag ttgaaaaaat gattactctt ggtaaacgtg gtgatcttca
     4441 tgctcgtcgc caagcagctg catacgttcg taacgaaatc gcatcagaaa actatgatga
     4501 agctactgat aaatacacat caacaacagc tcttcaaaaa cttttctctg aaattgcgcc
     4561 tcgttatgca gaacgcaacg gtggatacac tcgtatcctt aaaacagaac cacgccgcgg
     4621 agatgctgct ccaatggcga ttattgaatt agtttaattt ttatcaattt tgttgagtgt
     4681 tatgatgatg gagcagttcc tttaagctgt tcttagtcta gctctggtct accgctagga
     4741 cctttcctag cggtaacact caccatgttg agaataagta acgcttgttt acgaaaggtc
     4801 tctaagctgt aggtgccctt cgtaagcagg cgttttgttg tgactccatg ttaactgtag
     4861 tagatgacta atatctaata tctagagagg atcagcttgg tgctctcttt tctgatatta
     4921 aaagcattgg gaatcttggt tttgaagttc ttaaagctcc taaagccaaa gtctttcgct
     4981 tgatgtcttt ggtcatcttg ttagtggtct ccggcttagc attggaataa ggtagttcaa
     5041 agcattggtg atgtaagatc tatacttcct gaaggtcttg aaaaccgttt tgaaggtgtg
     5101 attgacctgt agcgggagta gattagatca atggcgtttg gctgctttga aaatttaggt
     5161 gacaattgtt tttgtatctt
//
LOCUS       DARYXS010000110         5017 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.111, whole genome shotgun sequence.
ACCESSION   DARYXS010000110 DARYXS010000000
VERSION     DARYXS010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5017
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.111"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(463..1023)
                     /locus_tag="TV193_001744"
     CDS             complement(463..1023)
                     /locus_tag="TV193_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1513909.1"
                     /translation="MTSKRLTDQIELSLFAALIFISVELLRIPVGAQFIHLGNALVVV
                     AVLLYGARRAALVAAIGLGLFDMINGYAAVVWITVLEALVVCYLLHVIYEKLLKSVDK
                     PMIIVAIGLLAAAAKLVMNLVKYSLIAYFGAQLPLSVALWAALGKIGGSLGTALVTVI
                     AVPLLYPVFKQLRQAVKKQEASNRLG"
     gene            complement(1001..1870)
                     /locus_tag="TV193_001745"
     CDS             complement(1001..1870)
                     /locus_tag="TV193_001745"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEL1513910.1"
                     /translation="MLKRVIVANDIVGVGKVALSASIPIMAACQIEQAILPTCLLSSH
                     TAIAKTPYIQSTSEGLKPFLTTWSQAGLAFDGFFSGYLYRPDDALIILDYIKKQQLPF
                     VLDPIMADKGSMYAQLTSQHLSAMRLLAQAAQLILPNVTEACLLADVPYFGETYSRED
                     LERLLSKLATLGPREIVLTGISFDDQHIGFAYYQKATETVSYHFGKRYPYHFYGTGDL
                     VSAIVSAGYFHRLAIDELLDMVISFLDKSLAATVALNRELSLGIAYEVELGSLGAAFR
                     GLLEEKDDIKTID"
     gene            1962..3233
                     /locus_tag="TV193_001746"
     CDS             1962..3233
                     /locus_tag="TV193_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEL1513911.1"
                     /translation="MTSKYQQIIADLELAMQSNQFKKGEKLPSIRQLSQQYHCSKDTV
                     QRALLALQYKRLIYAIPKSGYYVLGKIEEKQHSFELSLEDYNQLAYEDFRLCLNEALD
                     GKDSDLFNYYHKAEGLEELREALLPYLADNGIYANKNQLLITSGTQQALYILAQMRFP
                     NGRHHILLETPTYHRMEQLATSLGLPYQTIERDVNGINLHQLESIFKTGQIAFFYTIS
                     RFSNPLGLSYSKKEKESIVRLAEQYQVYIVEDDYLGDFASHSELPLHYYDTQHRVIYL
                     KSFSMSVFPALRIGALLLPDDLKEGFLLQKSMIDLDTNLIMQKALALYLANGMFQKNL
                     KQMRQFFNNRAHNLLDFLQKHLPNLAYQLTPQALIIQLDKAFNRKKLLKPHHTQIIST
                     RKARYMLLTISPDMPSKLLDLFSVTHEKTQE"
     gene            complement(3269..3607)
                     /locus_tag="TV193_001747"
     CDS             complement(3269..3607)
                     /locus_tag="TV193_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513912.1"
                     /translation="MQIIKRDGQLADFDPDKIYQALIKAARTVYVIDDSWRQHLAQVT
                     KKVVIDLEEVQAERPTINMIQSLVENRLIDAGYMTIAEHYIAYRLQRDLERNGYGDSI
                     SVHLRFEQIK"
     gene            complement(3707..4795)
                     /locus_tag="TV193_001748"
     CDS             complement(3707..4795)
                     /locus_tag="TV193_001748"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEL1513913.1"
                     /translation="MGYTVAVVGATGAVGQQMIKMLEESSLPISAIKLLASARSAGKI
                     LSFKGEDFVVEELTKAAFQGIDLALFSAGGNVSAKYAPYAVAAGAVVVDNTSYFRQHP
                     AVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
                     GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYT
                     YEEMKMTNETKKIMEDDTIKVSATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQF
                     PGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPAQDNLFDPSVSFD"
BASE COUNT         1578 a         1158 c          911 g         1370 t
ORIGIN      
        1 aaagccttga aagtgcctgc tttaatttat actatcattc ggaaagaact gtttcgctcg
       61 tttgttgtgg aaagccgctc acaacaaaga catagagagt ctatgacaac aagagctaca
      121 ctttagcaag tcttgaccga catgctttat tgcccagtct aattcattaa aaagcgaaca
      181 ggtctagctt tcggaatttc agaaaactag gcctgttcat ttgttctatt ttgaggcagc
      241 cttttgtttc ggcctcgtct gtttcaaggt tttcagatcg aacttaagga caaaaaacac
      301 tctcctgtat cagctaacct tatcattcat tataaaggaa aatgatttct aatacaagga
      361 aataccgtta tttcattaaa aataactaaa aatagtttgt caaatcatta gttattaata
      421 ggcttagata acaaaaatga tgatactgct agcaaggtta gctcaaccaa gcctattact
      481 cgcttcttgc ttttttactg cctgccttaa ttgcttaaaa acagggtata agagaggcac
      541 agcaataacg gtcacaaggg cagtaccaag actgccacca attttgccaa gtgctgccca
      601 caaagcaaca gacaggggta actgggcgcc aaaataagca atcaagctat atttcacaag
      661 attcatgact aattttgctg ctgctgctaa taagccaatt gctacaataa tcatcggttt
      721 atcaactgat ttcagaagtt tctcataaat cacatgaagc aggtaacaaa ccactaaggc
      781 ttcaagcact gttatccaga ccacagccgc atagccatta atcatatcaa acagtcctag
      841 accaatggct gccaccaaag ctgcccttct agcaccatac aataaaacag ccaccaccac
      901 taaggcattc cctaggtgaa taaattgggc tccaactgga atacgcagca gctcaaccga
      961 tataaaaata agagcagcaa ataggctaag ctcgatctga tcagtcaatc gttttgatgt
     1021 catctttttc ctccaataat cctctaaacg cggctcccaa gctgcccaat tctacttcgt
     1081 aggcaattcc aagtgaaagc tctcgattta gcgcaacagt agccgctaat gacttgtcta
     1141 agaagctaat aaccatatcc aacaactcat caatagcaag cctgtgaaaa tacccagcgc
     1201 taacaatagc agagacaaga tcacctgtcc catagaaatg ataagggtac cgttttccaa
     1261 aatgatagct aaccgtctct gttgcctttt gataataagc aaagccgatg tgctgatcat
     1321 caaaggatat accagtaagg acaatctctc taggtcctag tgtagctagc ttagacaata
     1381 gcctctccaa atcctctctg ctataggtct ccccaaaata aggaacatca gctaacaaac
     1441 aagcttccgt cacatttggc aatatcagct gtgcagcttg agcgagcaat ctcattgccg
     1501 ataagtgctg cgaggttaac tgcgcataca tgcttccctt gtcagccata ataggatcta
     1561 gcacaaaggg aagctgttgc tttttgatgt aatcaagaat aatcaaagca tcatcaggac
     1621 ggtacaaata accggaaaaa aagccatcaa aggcaagacc cgcttgagac caagtcgtca
     1681 aaaatggctt tagtccctct gacgtgctct gaatataagg cgtcttagca attgcagtgt
     1741 ggcttgataa caaacaggtt ggaagaatgg cctgttcaat ctggcaagcc gccataatgg
     1801 gaatactagc agacagagca accttgccaa ctccgacaat atcatttgca acaataacac
     1861 gttttaacaa ccaataagct ccttcatttc tttttttact attgtaagaa aatccttgat
     1921 gagatacaat aaggatagat ttcatctgta tggggacact tatgacaagt aaatatcaac
     1981 aaatcattgc agacctagag ttggccatgc aatcaaacca attcaaaaag ggagagaaac
     2041 tcccttctat tagacaatta agtcaacagt atcactgcag caaggataca gtgcaaagag
     2101 cacttttagc cttacaatac aagcgcctca tttatgctat tccaaaaagt ggctattatg
     2161 tgcttggtaa aattgaggaa aagcagcatt cctttgagct aagccttgag gattataatc
     2221 agttggccta tgaggacttt cggctctgtc taaatgaagc cctagacggt aaagattctg
     2281 atttatttaa ctactatcat aaggctgagg gacttgagga gctgcgagag gctttgctgc
     2341 cttatttggc tgataatggg atttacgcta acaaaaatca gctgctaatt acctcgggta
     2401 cacaacaggc cctttacatt ttagctcaaa tgagatttcc caatggccgc catcacattc
     2461 tccttgagac accgacctat caccgaatgg agcagctagc gacttcctta ggcttaccct
     2521 atcaaaccat tgaacgtgat gtcaacggta tcaatcttca tcagcttgaa agcatcttta
     2581 aaaccggaca aatcgctttt ttctatacta tttctcgatt ttcaaaccct cttggcctct
     2641 cctacagcaa aaaagaaaag gaaagcattg ttcggctggc agagcaatac caggtttaca
     2701 tcgtagagga cgattatcta ggggactttg catcgcatag tgagcttccg ctacactact
     2761 acgacactca acaccgggtc atttatctga aatcattttc aatgagcgtc tttcctgccc
     2821 tgcgcattgg agccttgctt ttacctgatg atctcaagga aggctttttg ttacaaaagt
     2881 caatgattga ccttgatacc aacctgatca tgcaaaaggc actagcatta tatttagcaa
     2941 atggtatgtt tcaaaaaaac ctaaagcaaa tgaggcaatt tttcaacaat agagcgcata
     3001 acttactaga ttttctacaa aaacaccttc ctaacctagc ttatcagctc actcctcaag
     3061 cactgattat tcaattagat aaagcattca atcgcaaaaa gcttcttaaa ccacaccaca
     3121 cccaaatcat ctcaacaaga aaagcaaggt atatgcttct aacaatcagt cctgatatgc
     3181 catctaagct gctcgacttg ttttcagtga cacatgaaaa gacccaagaa tagctcattg
     3241 ggtctcagtg tcacaaaaat gtcaatagct atttgatttg ctcgaatcgt aaatgaacac
     3301 taatgctatc gccgtaaccg tttctctcca aatctctttg gagccggtaa gcaatataat
     3361 gctctgcaat agtcatgtag cctgcgtcaa tcagacgatt ttcaacaagt gattgaatca
     3421 tattaatcgt cggacgctcc gcctgcacct cttctagatc aataacaacc tttttagtta
     3481 cctgagctag atgctgtctc cagctgtcat caatcacata aactgttctt gctgccttga
     3541 tcaaagcctg ataaatctta tccggatcaa agtctgccag ctgaccgtca cgcttaataa
     3601 tttgcataag agcgcctctt ttcatttagt ttcattgctt acattcatta tgcaaatgtt
     3661 ttcatcattt gtcaagctat taggctccta tgcctcttag ggattatcag tcaaaagaaa
     3721 cactaggatc aaataaattg tcctgtgctg gtcggacaag cccacgctcg tgcaaggtct
     3781 ctgcaatctg aacagaattc caggctgcgc ccttgagcag attgtcagat accacccaca
     3841 tgtgaatgcc cttttcaaca tctaaatcct tacgaagcct tcctacaaag gtctcacgac
     3901 tgccaacagc attaacggcc tgtgggtatc gttgcactcc ggtatcgtcc tctaaaacag
     3961 cacccggaaa ttgtgcaatc gcctccttaa cagcttcgat agtagctact gccttggttt
     4021 caatgtagat agattctgaa tgggctgata aaacgggtat acgaacacag gtcgcagaca
     4081 ccttaatcgt atcgtcctcc atgatttttt tcgtttcatt tgtcattttc atctcttcat
     4141 aggtgtagtc attttcagtg aaacgatcaa tctgtggtaa agcattaaaa gcaattggat
     4201 aatgtctctt gtcaccagct gacggtaaaa cacttgcctc cacctcctta ggagacaagc
     4261 cctggttaat aacctggtca tactgagcta gggtctcacg aatcgctgat tgaccagcac
     4321 ctgaaacagc ctgataggtg gaaacaataa tacgctcaag accccacctt tgacgaatag
     4381 gctccagcgc tatcatcatt tgaatcgtag agcaattagg gcaagcaaca aggccttgat
     4441 gtgtatcaag agcgtgagca tttacctcag gaacaacaag tggaacagct gggtgctgac
     4501 gaaaataaga ggtattgtca accacaacag cacctgccgc aacagcataa ggggcatatt
     4561 ttgcagaaac attgcctcct gctgaaaaaa gggctagatc aatgccttgg aaggctgctt
     4621 ttgttagctc ctcaacaaca aaatcctctc ccttaaatga gaggattttt cctgctgaac
     4681 gtgcagacgc taataattta atagctgaaa taggcagact tgactcctcc agcatcttaa
     4741 tcatttgctg accgacagcg cctgtcgctc caaccactgc tactgtatac cccatagatc
     4801 gacctcactt taactgatga tattgcaaaa aatgatattg gacctattat agcctatttc
     4861 atcacaaaag aaaagcaagc tagaagccag aacaaacgca tgaagaaaat catttattga
     4921 aaaagttgtg aaaatagcaa aatatccatt ttagagtatt ttgacagagt gtttcctgaa
     4981 tttttatatt tttcctctat aaacttttct tgaaaaa
//
LOCUS       DARYXS010000111         4903 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.112, whole genome shotgun sequence.
ACCESSION   DARYXS010000111 DARYXS010000000
VERSION     DARYXS010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4903
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.112"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            50..505
                     /locus_tag="TV193_001749"
     CDS             50..505
                     /locus_tag="TV193_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEL1513914.1"
                     /translation="MEYDKLPSWKDLPDLELYLDQVLLYVNQVTQLSQATDHKLLTAS
                     MINNYVKHGYIDKPIKKKYQKKQVARLIAISILKNVFPIQDISQVLTSLQAASSSEVL
                     YDTFVNYWNNGLTQSTPEIISYACQTVKDYQHTMKLSREMEDTKHEPNL"
     gene            489..1139
                     /locus_tag="TV193_001750"
     CDS             489..1139
                     /locus_tag="TV193_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEL1513915.1"
                     /translation="MNQTFKQSLPLSVNEEVANSVTHAIGAAAMLILLPITAIYSYQT
                     YDLKAAVGASIFIISLFLMFLSSTIYHSMSYGTTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVEGLLGYVIIILQWGITLFGILYKIFAKTINEKFSLALYIIMGWLVVFILPVII
                     QKASLPFGILMLLGGLSYTVGAGFYAKKKPYYHMIWHLFILLASALQVIAIIFYML"
     gene            1249..2153
                     /locus_tag="TV193_001751"
                     /pseudo
     CDS             1249..2153
                     /locus_tag="TV193_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515585.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            complement(2506..2781)
                     /locus_tag="TV193_001752"
     CDS             complement(2506..2781)
                     /locus_tag="TV193_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513916.1"
                     /translation="MKKSYGIGLGLLLGSAAIAVTYLSLSSAKKKELLKEGSETIEEL
                     NHYIQEKGGQLIETASDKVEASKVAANACGHSAAKAIKGTLEEAIKI"
     gene            complement(3204..4754)
                     /locus_tag="TV193_001753"
     CDS             complement(3204..4754)
                     /locus_tag="TV193_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1513917.1"
                     /translation="MSILEVKQLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDAGKIEWSKYVTAGYLDQHTVLEPGQTVRDVLRTAFDELFKTEERIN
                     AIYMSMAEETADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMETEVT
                     SLSGGQRTKILLAKLLLEKPDILLLDEPTNYLDAEHIEWLKRYLQHYDNAFVLISHDI
                     PFLNDVINIVYHVDNRNLVRYSGNYDQFKEVYEMKKAQLEAAYERQQKEIAELQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFEFKEARTPSRFIFQTRELVIGY
                     DRPLTKDPLNLTFERHQKVAIIGANGIGKSTLLKSLLGIIQPLSGEVETGDFVELGYF
                     EQETAGVKRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQGLSGGEQAKVR
                     FCLLMNREHNVLILDEPTNHLDVDAKEELKRALQVYKGSILMVCHEPEFYEGWVTDIW
                     DFNQLTSL"
BASE COUNT         1434 a         1072 c          879 g         1518 t
ORIGIN      
        1 taaataatat ataatctagt tatcaaaact agataaagag gttttagtaa tggaatatga
       61 taagctgccc agctggaagg atttacctga tttggagtta tacttagatc aagtgttact
      121 ctatgtcaat caggtcacac aattgagtca agccacagac cataagctac tgactgcttc
      181 aatgatcaat aactatgtca aacatggcta tattgataaa cctattaaga aaaaatatca
      241 aaaaaagcag gttgcccgct taattgctat tagcattttg aaaaatgtat ttcctattca
      301 agatattagt caggtcttga cgagcctaca agcagcctcc agctcagagg tcttgtacga
      361 tacctttgtc aactattgga ataatggcct tacccaatca acgcctgaaa ttattagcta
      421 tgcttgtcaa accgtcaagg actatcagca cacaatgaag ctttcaagag aaatggagga
      481 taccaagcat gaaccaaacc tttaaacaaa gtctcccact atcagttaat gaagaggtcg
      541 caaatagtgt gacacacgct attggagcag ctgctatgct gatactgcta cccatcactg
      601 ctatttactc ttaccagact tatgatctca aggctgccgt tggagcatct atttttatca
      661 tcagcttatt tctcatgttt ttatcatcaa cgatttacca ttccatgtcc tatggaacaa
      721 ctcacaaata cattttacgt atcattgatc atagcatgat ttatattgct attgctggta
      781 gctatacacc tgttgcctta tccttggttg agggcttgtt gggctatgtg attatcatac
      841 tccagtgggg aatcacactt tttgggattt tgtataaaat ttttgctaaa acgattaatg
      901 aaaagttcag tcttgcgctt tacattatta tgggctggtt ggtcgttttt atcctgccgg
      961 tgattatcca aaaggccagt ctgccatttg gaatcttgat gctactaggt ggcttatcct
     1021 atactgtcgg cgcaggcttt tatgctaaaa agaagcccta ttatcacatg atctggcacc
     1081 tttttatcct tttagcctct gctttacagg ttattgccat tattttctat atgctgtaaa
     1141 aagtagctgt tgctactttt taaacgcgag cgcttgctta cccccagaca cctggcttga
     1201 ttcatgctat aataaagggc agtaaatagt tgaagggatc aaagcaatat gaaaacggta
     1261 catatttttt acaatcctaa ttcaggaaaa ccagaaaatg acctggctga aaaggtcaag
     1321 cattatctga ttcaaaatgg tttttctgaa gacaaggttc agattattac ccccaaaaat
     1381 gctgatcaag cctttcaatt agccaaaaaa tcctcacagg atcatattga tctagtcatt
     1441 cctctaggcg gagatgggac acttaataaa attattggag gtgtttatga aggtggtgct
     1501 cattctgtta ttggactcgt accgtcgggc actgtcaata actttgcaaa ggccttaaac
     1561 attccactcc agctaactga ggcacttgag acgattttat ctggcacgat taaaaaagta
     1621 gatatttgca aggtaaacaa gggctatatg atttctagcc taaccttggg tctgcttgct
     1681 gatattgcgg ctaatgtgac tacagaagaa aaacgaaaat ttggcccttg gcctttttaa
     1741 aggatagtat taagatacta aaacgaaacc gcacatatgc aattagctta attagccatc
     1801 atcatgttct tcacttgaaa accaaattct tattgattac cacaaccaat actatagcag
     1861 gtcttccatc gttttcacca ggtgcacaag ctgacgatgg cttgtgtcaa gtttacacga
     1921 tgagccagct atcatttctg aaatgcttgc gccatattag agactttaga cggggggatt
     1981 tttccaaggt aaaggagatt agccattttc aagctgattc tctaaagcta ttgccacaat
     2041 atcagcgtca atcagccatt cctagaactc gcattgatgg cgataaggct gatgatctcc
     2101 ctgttgaatt gaaggttatt ccaaaagcga tttccattat tgttagccag taaaaaagtg
     2161 ccctagggca ctttttgata tagattcatc tccaagctga gttttagaaa actaagctat
     2221 agctataacg ttagctgtgg cttcttcttg ctggcttgca gtactctttt cttgtcttaa
     2281 cagctagctc tttcataata tcggctttaa caaagaagct atctgactag tccgatcttc
     2341 tattctcagg acaaacagcg agaaagggga ttttctttga atcctagaga accttagcta
     2401 tctctgtgtc tcattgtaag tgcagctcta ttgactgatg ccagctatag caataagccc
     2461 agtcgcatat tataaaggat tatcaggcga tttagcttga cactcttata tctttattgc
     2521 ttcttctaag gttcctttaa tagctttagc tgctgaatga ccacaggcat tagcagcaac
     2581 cttagaggct tctaccttat cagaggctgt ctcaataagt tgtccaccct tttcttggat
     2641 ataatggttc aactcctcaa tagtttcaga gccttccttt aagagctctt tctttttggc
     2701 tgaggataag cttaaatatg tcacagcaat tgctgctgaa ccaagaagta atcctaagcc
     2761 gattccatag ctttttttca tcatcaaccc tactttctat gaccttcctt aatcatcttt
     2821 ttagctaatt ttacagctgg tactactaaa agcaccaatt gtaaaagatc catatacttg
     2881 atttttcgtc gttttttcac catgtgctat ttcctttttc ttgtttgcac catacaatcg
     2941 tcttttattg cgcagtgcca gagactgcct gattaggcag cgtaagctaa gaactatcag
     3001 cgtgtcagac tagtctagat acagctaagc actagcttga ttacgataat acttaccgct
     3061 aggccataag ctcagctatc atcaaatcta aagtgacaac gctttttatt tattatattg
     3121 tcattttact aaaatacaca attatcgtca atgcttttgc tttaggcagc aaaaatgccc
     3181 aagataaaga ccttggacat ctgctacaat gacgttaatt gattgaaatc ccaaatatca
     3241 gttacccagc cctcataaaa ctccggctca tggcaaacca tcaaaataga gcctttatag
     3301 acttgcaagg cgcgttttaa ctcctcctta gcatctacat ctaaatgatt ggttggctca
     3361 tctaggatta aaacattgtg ctcacgattc attaagagac aaaaacgaac cttggcttgc
     3421 tcaccacccg agagcccctg aatctggctt tcaatatgct tagaggttag accgcaacga
     3481 gctaaggctg cccgaacctc tgcttgattt aaagcaggaa aagcgtccca tactgcttct
     3541 agtggcgttt gacgcttaac acctgcagtt tcttgctcaa aataaccaag ctccacgaaa
     3601 tctcctgttt ccacctctcc tgacagtggc tgaataatgc caagcaggct ctttaggagg
     3661 gttgacttac caataccatt agcaccgata attgcaactt tttgatgacg ctcaaatgtt
     3721 aagttcaagg gatcttttgt taggggtctg tcatagccga tgacaagctc ccttgtttgg
     3781 aaaataaagc ggcttggtgt tcttgcttcc ttaaactcaa agcttggctt tggtttttct
     3841 gcctgaagct caatgatttc cattttatca agcttctttt gacgggacat agccatattg
     3901 cgagtagcta ctctggcctt attacgattg acaaaatcct gtagctctgc aatctctttt
     3961 tgctgacgct cataggctgc ctctagctga gcttttttca tctcatagac ttccttaaac
     4021 tgatcgtaat ttccagaata cctaaccaaa ttccgattat caacatgata aacaatatta
     4081 atgacatcat ttaaaaaagg aatatcatgt gaaatgagca caaaggcatt gtcataatgc
     4141 tgtaaatagc gctttaacca ctcaatatgc tcagcatcaa gataattggt cggctcgtcc
     4201 agcagcaaaa tatctggctt ctccagtaac agcttggcca gcagaatctt ggttctttgc
     4261 cctccagata aggaggtcac ttctgtttcc atcccaaaat ccataactcc taaggcacgc
     4321 gcaacctcat caatcttagc atctagggta taaaagtccc tgctttcaag acggtcctgt
     4381 agctctccga cctcctccat taaggcgtcg acatcagctg tctcctctgc catagacatg
     4441 taaatggcat tgatacgctc ctctgttttg aatagctcat caaaggctgt cctaagaaca
     4501 tcacgcacag tttgaccagg ttctaaaacg gtatgctgat ccaaatagcc tgctgtaaca
     4561 tactttgacc attcaatctt accagcatca ggctgcaagt gaccagtaac aatactcata
     4621 aaggtggact tgccttctcc atttgctcct actaatccaa tatgctcgcc ctttaaaaga
     4681 cgaaaggaaa catcttcaaa aatggcacga tcaccaaatc catgacttaa ctgcttaact
     4741 tctaatatgc tcatgattac tttcctttat tgtcatcaaa aaagccgtta aaacggctta
     4801 cactctctca attatggcaa aaatgcagcc ttttgtcaat gaaggctgaa aaagcctacg
     4861 tcatacgcat gaaagatttt tagcaagaac agaaggtttt ttg
//
LOCUS       DARYXS010000112         4893 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.113, whole genome shotgun sequence.
ACCESSION   DARYXS010000112 DARYXS010000000
VERSION     DARYXS010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4893
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.113"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(37..1368)
                     /locus_tag="TV193_001754"
     CDS             complement(37..1368)
                     /locus_tag="TV193_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEL1513918.1"
                     /translation="MEFLGPIGVLLGIIAIVYFSLKEIHITIAAPMATILVVLLNSMP
                     LVESLLGKEPNNYMGALGGYIMSYFAIFLLGSILAKLMEVSGATVSIAEFILKKVGYQ
                     NPYRILVAIFIISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLNTSLTAALVPSILGSVGCIAFGLFYMKRCLTKSLEVG
                     ENYATYTSQTNEDTTERVLPPFVVSILPLILLIVIAIIGSLLGDEFVKKNIIYVALLT
                     GIISAIVLFNKYIDKKIATLSIGASGAVGPIFATASAVAFGSVVTAASGFGVFSDIIL
                     NIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVASN
                     ILTIVPQSGVFLTFLSLTGLSHKNGFKQTFITVFGGTLVAESIIMLTSLFF"
     gene            complement(1459..2238)
                     /locus_tag="TV193_001755"
     CDS             complement(1459..2238)
                     /locus_tag="TV193_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEL1513919.1"
                     /translation="MNMSKQVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDA
                     VVDEYTTKGWAADSVLCDVTNEEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFP
                     TAKYEFMLKVMLTAPFIAIKRAFPTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHG
                     LIGLTKVAALEAAELGITVNAICPGYVDTPLVRGQFEDLSKTRKIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGITGQPVILDGGYTAQ"
     gene            complement(2269..2913)
                     /locus_tag="TV193_001756"
     CDS             complement(2269..2913)
                     /locus_tag="TV193_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEL1513920.1"
                     /translation="MVKELSKEEIQERIAKRVALELPNNSLVNLGIGLPTKVARFLPE
                     GVTIMLQSENGFVGLDKVGDDIDPTIVNAGGQPVGIVPGGAFFDSTTSFGIIRGGHVD
                     ATVLGALQIDEKGNIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKWKILKE
                     CSLPLTAAGVVDKIVTEMGVFTVTPEGIAVEEIHPDYTFEEVQEATEARLIYHN"
     gene            complement(2919..3569)
                     /locus_tag="TV193_001757"
     CDS             complement(2919..3569)
                     /locus_tag="TV193_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEL1513921.1"
                     /translation="MNKRISIEEAVNLVKDGDTIMVGGFMTNGSPERLIDALVAKGVT
                     NLTLICNDAGFPDKGVGKMVAQHRFRKIIASHIGLNKEAGRQMTAGETVIDLVPQGTL
                     AERIRAGAYGLGGFLTPTGIGTLVEEGKQKLQVNDKDYLLELPLKADVALIFADKADE
                     LGNLCYKGSENNFNQVMAANAKVTIVEAREIVSLGDIEPIAVQTPGIFVNYLVEGE"
     gene            complement(3584..4774)
                     /locus_tag="TV193_001758"
     CDS             complement(3584..4774)
                     /locus_tag="TV193_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEL1513922.1"
                     /translation="MLVKEVVITTAVRTPIGSFGGAFKSVSAVQLGKVVVEALLEKSG
                     VKPEQIDEVIFGNVLHAGLGQNVARQVGITAGIPNDKPAFTVDMVCGSGLKSIELAAQ
                     SIVCGDSDIIIAGGTENMSQASYVLKDYRWGGRLGDGKIIDTMVNDGLTDAFHDYHMG
                     ITAENIAKNYGISRKAQDIFALASQEKAAAAQAAGRFVDEIIPVPVPQRKGDPILVAE
                     DEYIKAGTTLEKLTALCPAFVRDGSGTVTAGNASGINDGAAAVLLMSRDKAEELGLPI
                     LGAIKGYASAGVAPEVMGTGPIPSTQKALAKVGWTIEDLDLVEANEAFASQAISVVDE
                     LGLNAAIVNVNGGAIALGHPIGASGARILVTLLHEMEKRQAHKGLATLCIGGGQGTSV
                     LIEK"
BASE COUNT         1436 a         1161 c          894 g         1402 t
ORIGIN      
        1 taatagacca atggttttcc attgatctac tgtgtattaa aaaaacaggc tagttaacat
       61 aataatgctc tcggccacca acgtaccacc aaaaactgta ataaaggttt gtttaaagcc
      121 atttttatgg ctgagaccag taaggctcaa gaaggttaaa aagacgccag actggggtac
      181 aatggtcaaa atattagagg caacagctgc cacacgatga atgatctcag gtgaaacgcc
      241 tgcatctaaa taatattgag caaaatttgg cattacgatc cctaacgctc ctgaagacga
      301 acctgtaata gctgccatag ccgaagtcag gacagtcaag ctgatcacag gtggcccagg
      361 aatattcaaa atgatgtctg agaatacgcc aaaaccagat gctgctgtaa caacagaacc
      421 aaaggctact gcagaggctg tcgcaaagat tggaccaacc gcaccgctag caccaatgct
      481 gagggtcgca attttcttat caatgtactt gttaaataaa acgatagctg aaataattcc
      541 tgtcaagagg gccacataaa tgatattttt cttaacgaat tcgtccccta gcagactacc
      601 tatgatggca ataacaatca agagtatcaa aggcaagatg ctgactacaa atggtggtaa
      661 aaccctttca gttgtatctt catttgtttg actagtatag gtcgcatagt tttcgccaac
      721 ttctaaactc ttagtcaaac aacgcttcat atagaaaaga ccaaaggcga tacagccaac
      781 actccctaaa atacttggca ccaaggctgc ggttagagac gtgttaagat attgtatagg
      841 gataacgttt tgaatcgctg gtgtaccagg taagatcgtc atagtaaagg ttgcaatccc
      901 caaccaaagt ggtacttgaa ttaagttcca tgctaagtcc atctttttaa agagagagcg
      961 tgccaagggt agaacagcaa acatgaccac aaagagacta ataccaccat aagtcaaaat
     1021 agcactgatg ataaaaatag ccaccaagat acggtaaggg ttttgataac ctactttttt
     1081 caagataaat tcagcaatgg aaactgttgc accactgact tccatcaatt tagctaaaat
     1141 agaccccaac aagaagatag caaagtagct catgatatag ccacccagcg cacccatata
     1201 gttatttggt tccttaccca agagtgactc aactagtggc atactattta gaaggacgac
     1261 caaaatcgtt gccataggag ccgcaatggt aatatgaatt tcctttagag aaaaataaac
     1321 gatggcaata atgcccagca agaccccaat tggtcctaaa aattccatag tgtttctcct
     1381 ctcacattca gaaggagcaa gagatagaga aatgtcactc tatctccaat cctcttattt
     1441 acactgaacg gacagctctt actgagcagt gtagccacca tccaagataa ccggttgtcc
     1501 agtaattccc tttgccttat cacttgctag gaaggagaca taatctgcaa tttcttgtac
     1561 gtcaatcaaa cgtttttgcg gtaccaacgg gtacaacact tcttccaata cattttcaag
     1621 cggaatctta cgtgtcttag agaggtcttc aaattggcca cgaacgagtg gtgtgtccac
     1681 atagcctgga cagatagcgt tgactgtgat acctaattct gcggcttcaa gcgctgcaac
     1741 ctttgtcaag ccaatcaaac cgtgttttgc tgaattgtaa gccgcttttc cggcaaaacc
     1801 aatgacacca ttgatagaag ccatattaat gacacgacca aagccttgct ttttcatagt
     1861 tggaaaagcg cgcttaatag cgataaatgg cgctgtcaac atgaccttca acataaattc
     1921 atattttgct gttggaaaat cttcaatcat ggcaacatgc tgcaaacctg cgttgttgac
     1981 caaaatatcc aaacgaccat gcttttcaac tgtataatca atcgctttat tgatcgcttc
     2041 ttcatttgtc acatcacaca aaacagaatc agccgcccag ccttttgtgg tatactcatc
     2101 aacaacagca tctaattttt cttgattgat atctgaaaag acaacgattt tgccctcttt
     2161 taagaatgtt tcaccaattt gtttaccaat accgcttgct gcacctgtta cgaatactac
     2221 ttgtttagac atatttattt cctcactttt tttaaatatt gttttctatc agttatgata
     2281 aattaatctt gcttcggtgg cttcttgaac ttcttcaaag gtataatctg gatgaatttc
     2341 ttctactgcg attccctctg gagtgactgt gaagacaccc atttctgtga caatcttgtc
     2401 aacaactcct gctgctgtca atggcaatga acactccttc aagattttcc atttgccttt
     2461 attggtatgc tccatagcaa caatgacttt tttagcaccg actagtaaat ccatggcacc
     2521 gcccattcct ggaaccattt tccctggaat aagatagttt gcgatgtttc ctttttcatc
     2581 aatttgcaaa gcgccaagaa ctgttgcatc gacgtggcca ccacgaatga tcccaaatga
     2641 agtggtgcta tcaaaaaatg ctccgcctgg tacgatgcca accggctgac cacctgcatt
     2701 aactatagtt ggatcaatgt catcgcctac tttatctaag ccgacaaaac cattctcaga
     2761 ctgcagcatg atagtcacac cttctggtaa aaatctagct accttggttg gcaagccaat
     2821 ccccaaattg accagggaat tatttggaag ctcgagtgcc acacgtttag caattcgttc
     2881 ttgaatttct tctttgctta attctttcac cataacgctc attctccttc cactagataa
     2941 ttgacaaata tgcctggtgt ttgaactgca atgggttcaa tgtctccaag cgagacaatt
     3001 tcacgcgctt caacgatggt cacttttgca tttgctgcca taacctggtt gaaattattt
     3061 tcagagccct tgtagcatag gtttcctaat tcatcagcct tatctgcaaa aattaaagcg
     3121 acgtcagctt tcaatggtaa ttctaacaga taatccttgt cattgacctg taatttttgc
     3181 ttaccttcct ctaccaaggt accgatgcct gtcggagtca agaagccacc cagtccgtaa
     3241 gctcctgctc ggattctttc agccaaggtt ccttgtggca ctaagtcaat cactgtttca
     3301 ccggctgtca tttggcggcc tgcttctttg ttcaagccaa tatgagaagc gataattttc
     3361 cgaaaccgat gttgtgctac cattttaccg acacccttgt ctgggaagcc tgcatcgtta
     3421 caaataagag ttaaatttgt aactcctttt gctaccaaag cgtcaatcag gcgctctgga
     3481 ctcccgttag tcataaaacc accaaccatg atggtgtcgc catcctttac aaggttaaca
     3541 gcttcttcta tgctaattcg tttattcatg aaaccatctc cttttatttt tcaatcaata
     3601 cagacgtccc ttgaccgcca ccgatacaga gtgttgccaa tcctttatgt gcctgacgct
     3661 tttccatctc gtgcaatagt gtgaccaaga tacgcgcacc gctagcaccg atcggatgac
     3721 caagagcaat agcaccacca ttgacattga cgatagccgc attaagacca agctcatcta
     3781 caacactgat agcttgtgag gcaaaggctt cattggcctc caccaaatcc aagtcttcaa
     3841 ttgtccaacc aaccttagca agggccttct gagtggaagg aattggccca gtacccatga
     3901 cctctggtgc tacaccagca cttgcataac ctttaatggc tcccagaatt ggaagaccaa
     3961 gttcttcagc tttgtcacga ctcatgagaa ggacagctgc cgcaccgtca ttaattcctg
     4021 aagcgtttcc tgcagtaaca gttcctgaac catctcggac aaaggccgga caaagggctg
     4081 ttaatttttc aagggttgtt ccagctttaa tgtactcatc ttctgccacc aaaattggat
     4141 cacctttacg ttgcggtact ggcactggaa taatctcatc tacaaagcga ccagcggcct
     4201 gcgcagcagc agctttttcc tgactagcca aagcaaatat atcttgagct ttacggctaa
     4261 tcccatagtt ttttgcgata ttttctgctg taattcccat gtggtaatca tgaaaggcat
     4321 ctgtcaaacc atcattgacc atagtatcaa tgatttttcc atcgcctaag cgaccacccc
     4381 aacggtaatc tttgagcaca tagctggctt ggctcatatt ttctgtccca cctgcaataa
     4441 tgatatctga atcaccacag acgatacttt gtgctgctaa ctcgatggat ttgagaccag
     4501 aaccacagac catatccaca gtgaaggcag gtttgtcgtt tggaatacct gcagttatcc
     4561 ctacctgtct agcaacattt tgaccgagtc ctgcatggag gacatttccg aaaatgacct
     4621 cgtcaatttg ttcaggcttc acacctgatt tctctagtaa tgcttctaca accacttttc
     4681 ctaattgaac agccgagaca gatttaaagg ctccaccaaa tgaaccaatg ggtgtcctaa
     4741 cagctgtagt gataacaact tctttaacca acatgcgatt ctccaatcta tttgttatag
     4801 aaagcgcttt ctgtttttgt gaatttattt tatcactact aaaagcgttt gcaaaattcg
     4861 atttttttat atgactataa aaaattttta tta
//
LOCUS       DARYXS010000113         4589 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.114, whole genome shotgun sequence.
ACCESSION   DARYXS010000113 DARYXS010000000
VERSION     DARYXS010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4589
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.114"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..405
                     /locus_tag="TV193_001759"
     CDS             <1..405
                     /locus_tag="TV193_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1513923.1"
                     /translation="GRGFYKKYMNAYGQVARLHSQQWYTDVVHLPVEFPMSADGHRPV
                     SERYRTLSDKEIREGFLSIGKTPELVSGSQVERLRKIINLYDLPVVVPIDEAVTQAEE
                     QIRTNREAVSKRIIEQYKEPSLKEKIKFISEF"
     gene            414..1085
                     /locus_tag="TV193_001760"
     CDS             414..1085
                     /locus_tag="TV193_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513924.1"
                     /translation="MISFKNISKTYQVGDQEVKVLDDVSFTIEKGRFTVILGPSGSGK
                     STLLNLLGGMDRASKGTFIFEGKDITALNDKALSDYRKEVVGFVFQFYNLIPSLTALE
                     NISIAAQLTGNTAQSEVLLDKVGLSHRKNNFPSQLSGGEMQRVSIARALAKKPKLLLC
                     DEPTGALDSKTGQHIMQLLQEASKDEDVAVVLVTHNTEFKAFGDTIIYLKDGKISSID
                     HKQSV"
     gene            1102..3375
                     /locus_tag="TV193_001761"
     CDS             1102..3375
                     /locus_tag="TV193_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513925.1"
                     /translation="MKYLNLKLRRDLKHHWQQFFSVFLMSLLSVLIFVGLQGAWHGLE
                     KSLDNYISTSHLPTVWVQATNLTKQDIEKIEALNQVSKVRPKIRVTAAIDSDSDLEHY
                     LTLDSLQSTSDQVTRVVAGEAFSTKETDKVWLNKEYADANHLSLGDKISLTLSGQSIS
                     VTLAGLVQSADRIYFTGSLEYIAPNYDNYAYGYISKKSLAKLLQTQLPDNMVDIYASS
                     DDLRDDIENILGNKLVSYYNQTTLTDVSEAVDRVGQIRNLSYLFSFIFILLAILSMFT
                     TIRRLIESQTKEIAIIKALGYSNIQVSGHYISFGLLVGTLGALSGLLVSPAMSWFVLE
                     TQKRMFSLPKWEIAYSLSSLVVALLVVMICVTSAYFASRKAIKGLPAVFLRGKNRDVK
                     HILLEKIKPLWRSISDEAKWAIRDALTHRIRILMGIIGVAGSMMLLIAGIGMPISMNH
                     LVDKAYNKDFSYSKRLTVSDYESANKAYKGQWVQINQAHFSKDDGYNRLLIIISKGSL
                     VNATTEDGDKIKEGGLYVTNSFAKLANIKVGDKLSVTPYQDKHQYTFSVKGILTSETN
                     QGAYIMADTFKKAGGAFHPHTLLVDKQVSASTIAQDQNVLTVIDKSSQESNAYDLVNS
                     LMSVFLMIIGFALLLVIVVLYNLGSLNFVERTRDYATLQVLGFSKRNLQNITMLENLM
                     TTSVGWLLGIPMGIWFLEQYVATFSTIRLEYTAYVTWQVLLAASVLVWLTSLMTTLFI
                     SRKIRTIDMVDALKGVD"
     gene            3849..>4589
                     /locus_tag="TV193_001762"
     CDS             3849..>4589
                     /locus_tag="TV193_001762"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1513926.1"
                     /translation="MITKKQRKLKRHTTIRRLCHQALAATLITGSLMGTGLLGNKVVY
                     GDMKSDAKKVLATLQKGNHKQELKKVLRTIGDDSLLLLWLLVSGDSNLDESNKSFDYL
                     SIWNTGSRVGKVISPTEYFKQESKNTENRQAVYSEFKQRVEERSKKAKEATEALNQKA
                     QLEATVKNINEELEKTREGFKVVSENSNKLEKQLMAEKIKTRTAEETAKQAKTDKEKA
                     EAEAKKAKEEAKTAEGKVKQAETEKRNAE"
BASE COUNT         1496 a          891 c          946 g         1256 t
ORIGIN      
        1 ggaagaggct tttataaaaa atacatgaat gcctatgggc aggtggcaag gctgcattct
       61 cagcaatggt acaccgatgt cgttcatctt cctgttgaat ttcctatgtc agccgatggg
      121 cataggccag tctctgagag gtaccggaca ctatcagaca aagaaatcag agaaggcttt
      181 ctctccattg gaaaaacacc ggagcttgtc agtggcagtc aggtcgagag attgcgaaaa
      241 atcattaacc tatatgacct gccggttgtc gttccaattg acgaggcagt cactcaagca
      301 gaggagcaaa tcagaaccaa cagagaagct gtctccaagc ggattattga gcagtataaa
      361 gagccttcat taaaagaaaa aataaaattt atatcagaat tttaggagtg tagatgattt
      421 catttaagaa tattagcaag acataccaag tcggagacca agaggttaaa gtattagacg
      481 atgtttcctt tacgattgaa aagggaaggt ttactgttat tttaggcccc tctggttcag
      541 gaaagagcac gctcttaaat ttacttggag gaatggaccg ggcaagcaag ggaaccttta
      601 tctttgaggg taaggacatt acagccttaa atgataaagc attatctgat tatcgcaaag
      661 aggttgtagg ctttgtcttt cagttttaca atcttattcc aagcctaaca gccttagaaa
      721 atatcagtat cgccgcacag ctaaccggaa acacagcaca atcagaggta ttgttggata
      781 aggtggggtt atctcatcgg aaaaacaatt tccctagcca gctgtcaggc ggagaaatgc
      841 agcgcgtatc catagccaga gctctggcaa agaagccaaa attattgcta tgtgatgagc
      901 ctaccggtgc ccttgattcc aaaacagggc agcacattat gcagctactt caggaagcgt
      961 caaaggacga ggacgtagcg gttgtcttgg tgacacataa cactgaattt aaagcttttg
     1021 gcgataccat tatttaccta aaggacggaa agataagctc gattgatcat aaacaatcag
     1081 tttagaggat tggagctaaa catgaaatat cttaatttaa agctaaggcg agatttaaag
     1141 catcattggc agcaattctt ttcagtgttc ttgatgtcct tattaagtgt tttaatcttt
     1201 gttggtctac agggtgcttg gcatgggctg gaaaaaagct tagacaacta tatatctacc
     1261 tctcatttgc caaccgtttg ggtacaggct actaatctaa caaaacagga cattgaaaaa
     1321 atagaggcct taaatcaagt cagcaaggtt agacctaaga ttagggtcac tgctgctatt
     1381 gattctgaca gcgacctaga gcattactta acgctagatt cattacagtc tacctcagat
     1441 caggtgacac gtgttgtagc tggcgaggcc ttttcaacca aagaaaccga taaagtatgg
     1501 ttgaacaagg aatatgctga cgctaaccac ctatccctcg gtgataagat cagcttaaca
     1561 ctatcaggtc aatcaattag tgtgactctt gcgggtcttg tccagtcagc agacaggatc
     1621 tactttacag gcagcttaga gtatatagct cctaattatg ataactatgc ctacggctac
     1681 atctcaaaaa agagcttagc taagctcctt cagacgcagc tgcctgataa tatggttgac
     1741 atttacgcct cgtctgacga tcttcgagac gacatagaga acattttagg caataagctt
     1801 gtttcttatt acaatcaaac aaccctaact gacgtctctg aggcagttga tagagtagga
     1861 cagattagga atctctctta tttgttctcc tttatcttca tcttactagc tattctatcc
     1921 atgtttacca cgatcagacg tctcatcgaa agtcaaacaa aggaaattgc tatcatcaag
     1981 gccttaggct attctaacat acaggtcagt ggccactaca tttcctttgg cttgttggtt
     2041 ggaacattag gtgctctttc tggtcttctg gtatctcctg ctatgtcctg gtttgtccta
     2101 gagacccaaa agagaatgtt ctcacttcct aagtgggaaa ttgcttactc tctgtcttcc
     2161 ctagtagttg cattactggt ggttatgatt tgtgtgacat ctgcttactt tgcttctcga
     2221 aaagccatta aagggctgcc agcagtattc ttacgaggaa aaaacaggga cgtcaagcat
     2281 attttgctcg aaaaaatcaa gcccttatgg cgtagtattt ctgacgaagc taagtgggct
     2341 atacgtgatg ctttgacaca ccgcatcaga attttaatgg ggattatagg ggtagctggt
     2401 agtatgatgc ttttaattgc cggtattggc atgcctatct ctatgaatca ccttgttgat
     2461 aaggcctata acaaggactt tagctactcc aaacgcttga cggtttctga ctacgaatcg
     2521 gccaataagg cctataaagg ccaatgggtg caaatcaatc aagcccactt ctcaaaagat
     2581 gacggctaca atcgtctctt gattattatc agcaagggaa gccttgttaa cgccaccaca
     2641 gaagatggtg acaagataaa agagggtggt ctctatgtta ccaacagctt tgccaagcta
     2701 gccaatatca aggttggaga caagctatct gtcacaccct accaggataa gcatcagtat
     2761 acctttagtg ttaagggaat tctgaccagc gaaactaatc aaggtgccta tatcatggct
     2821 gataccttca aaaaagcagg cggagctttt cacccacaca cattgttagt agataagcaa
     2881 gtttctgctt ctacaatcgc tcaggatcag aatgttttaa ccgtcattga taagtccagc
     2941 caagaaagca atgcctatga ccttgtcaat agtctaatga gtgtcttttt gatgatcatt
     3001 ggctttgcct tgctgctagt catcgttgtg ctgtataatt taggctcttt aaattttgta
     3061 gagcgcacaa gagactacgc aacccttcag gttctaggat tttcaaaaag aaatctccaa
     3121 aacataacaa tgctcgaaaa tctcatgaca acctctgtgg gctggctctt gggaattcct
     3181 atggggattt ggtttttaga gcagtatgtc gccaccttct ctacgatacg tcttgaatat
     3241 acggcttatg tcacttggca ggttctgcta gcggcaagtg tccttgtctg gctaacatca
     3301 ttaatgacca ctcttttcat cagtagaaag attagaacaa ttgacatggt tgatgcctta
     3361 aagggagtcg actaacctca ctttatcaca tacctgactc tctctctttt atggttaagc
     3421 atcatcactg cactggttct gatatgatga ctgataaagc tgtaattgtg ctgtaacaag
     3481 cactgtcatt acatagcaac acccttaaaa acaagcatca gatttggtgc ttgtttttga
     3541 atttattgct aatgctaaac gcaacgatta tcacaaatca tgcagtacac gcttataaca
     3601 gcttaagcat gcccattatt caaaaaacgt tgatcaaaat gacttccctg aagtttagat
     3661 cattcctcaa tttattgata caaatgtgat aaagtcatac gatcttcttg tttattaaaa
     3721 aaaaaaaaaa cgaaactacg gagagaaaga tgagctttgt cgtttctcac ttccaaccgc
     3781 catgttaaaa tcttctctga gaaagaatgt tataaaaaat aatcattcta tcaccaaagg
     3841 agagaaaaat gataactaaa aaacagagaa aactaaaaag acacacaaca atcagacgcc
     3901 tgtgtcatca agccctagca gctaccctca tcacaggaag cctgatggga acaggactac
     3961 ttggaaataa agtcgtgtat ggggatatga aaagcgatgc caaaaaggta ttagcaacat
     4021 tgcaaaaagg taatcataaa caagagttaa aaaaagttct tagaactatt ggtgatgata
     4081 gtttgctatt attatggtta cttgtatcgg gtgattccaa tttagatgaa agtaataaaa
     4141 gttttgatta tttatcaatt tggaatactg gatctagagt tggtaaagtg atatctccta
     4201 ctgaatactt taaacaagaa tcaaaaaaca ctgaaaatag gcaagctgtt tatagtgaat
     4261 ttaaacaacg cgtagaagaa cgatctaaaa aagccaagga agccactgaa gcactaaacc
     4321 aaaaagctca attggaggct acagttaaaa atataaacga agaacttgaa aaaactagag
     4381 aaggttttaa agttgtgagt gaaaactcaa acaaattaga aaaacaatta atggctgaga
     4441 aaataaaaac acgtacagct gaagaaactg ccaaacaagc taaaaccgat aaagaaaaag
     4501 cagaggctga agctaaaaaa gcgaaagagg aagctaagac tgcggaagga aaagttaaac
     4561 aagcagaaac tgagaaaagg aatgcggaa
//
LOCUS       DARYXS010000114         4272 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.115, whole genome shotgun sequence.
ACCESSION   DARYXS010000114 DARYXS010000000
VERSION     DARYXS010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4272
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.115"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            250..1263
                     /gene="nrdF"
                     /locus_tag="TV193_001763"
     CDS             250..1263
                     /gene="nrdF"
                     /locus_tag="TV193_001763"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1513927.1"
                     /translation="MTQYYYDRSQSPIDYALSQTKKSLRSVNWNQLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQRLITRTYTGLTLLDTVQATVGDVAQIQHSLT
                     DHEQVIYTNFAFMVAIHARSYGTIFSTLCSSQQIEEAHDWVVSTESLQERARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVAALSPEKQAEMKAFVFDLLYQLIDLEKAYLRELYDGFDLADDAIRFSVYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGVTEETIDDD
                     WEF"
     gene            1265..1672
                     /gene="nrdI"
                     /locus_tag="TV193_001764"
     CDS             1265..1672
                     /gene="nrdI"
                     /locus_tag="TV193_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1513928.1"
                     /translation="MAARVMLVYFSSRSNNTHRFVQKLDVRALRIPVTGEPLLVDEDY
                     ILIVPTYAAGGSDSKGAVPKQVIHFLNKANNRRHCKGVISSGNTNFGDTFAIAGPIIA
                     QKLQVPLLHQFELLGTQRDVIKVQAILAGDEAL"
     gene            1719..3893
                     /gene="nrdE"
                     /locus_tag="TV193_001765"
     CDS             1719..3893
                     /gene="nrdE"
                     /locus_tag="TV193_001765"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1513929.1"
                     /translation="MSQKESYLSLNALTRFKRADGTYHFDSDKEAVQRYLEEHVYPQS
                     LSFDSLEEKWRYLVAHDYYDQEILKAYSAECITEAFTYAYQQKFSFLSLMGAMKFYQS
                     YALKTLDGSQYLEHFEDRAVMNALFLANGDPDLVRDLIDQILSGRFQPATPTFLNAGK
                     KRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREVGSPIKGIENQ
                     ATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLNVHHPEILTFLDTKRENADEKIRIKS
                     LALGVVIPDITFQLARENKDMALFSPYDIKRVYGKDMSDIAITEEYDRLVANPAIKKT
                     YISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHPQKGRIVMSNLCSEIAQVSTAST
                     FEEDLTFKQIGEDICCNLGSINIAEAMKHAVGFEQLIATSVRALDHVSRASDVSCAPS
                     VEKGNAANHAVGLGAMNLHGFLATNHIFYDSAEAVDFTDLFFHTMAYYAFKASSQLAK
                     EKGAFAGFEQSTYADGSYFARYLTKEAKPKTAKVAALLERYGLRVPSVADWQELVATI
                     QETGLANAHLMAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGHLGRIYVPAYQISDDN
                     YAYYERGAYEVGPEPIINIVAAAQKHVDQAISLTLFMTDQATTRDLNRAYIHAFKLKC
                     ASIYYVRVRQDVLEGSEQYEEDTIVALTDTNASGEACQSCML"
BASE COUNT         1153 a          882 c         1011 g         1226 t
ORIGIN      
        1 aacataagaa ttaagtatac ttaattcagc cggggaaaaa agcgggctta gccttgctta
       61 caaagcagtt gctgactggt tagggatcat cagcaagaaa ttatcattag cctgtaggat
      121 tgccctttag agcaagtctt tttgtgttgt ctaaatgtgg cacttagcag tcttccctag
      181 tcctaaagct gtagaaggct tggcagctga aggattgata ttgcgactat caagcttgaa
      241 ggagaaaaca tgacccaata ttattacgac cgatcacagt cacccattga ctatgccttg
      301 tctcaaacca aaaaaagttt gcgctctgtc aattggaatc agcttaatga cgacaaggac
      361 ctggaggtct ggaaccgtgt gacgcaaaat ttttggctgc ctgagaaggt tcctgtttct
      421 aatgacctta attcttggcg ttctttgggg gaggattggc aaaggctcat cacaagaacc
      481 tataccggct tgaccttgct agatacggtt caagcaacag ttggagatgt ggcacaaatt
      541 caacattctt tgaccgatca tgagcaggtg atttatacta attttgcctt tatggttgct
      601 attcacgcta ggtcctatgg gacaatcttt tcgaccctgt gcagcagtca gcagatcgag
      661 gaggcccacg attgggtggt gtcaacagag agcttacagg agcgagcgcg tgtgttgatt
      721 ccgtattata ctggtgatga ccctctgaag tctaaggtcg cagcagctat gatgccagga
      781 tttttgctat atggtggctt ttacctgcct ttttacctgt cagctagagg caaaatgccc
      841 aatacctcag atattattcg cttaatcctg agagataagg tcattcacaa ttattacagt
      901 ggctacaagt atcaacaaaa ggtggcagcc ctaagtcctg aaaagcaggc tgagatgaag
      961 gcctttgtgt ttgatctgct ttatcagctg attgatttgg agaaggctta cctgagggaa
     1021 ttgtatgacg gctttgatct tgctgacgat gcgattcgct ttagcgtcta taatgctgga
     1081 aaatttttgc aaaatctagg gtatgattct ccctttactg aggaggaaac acgtatttcc
     1141 cctgaggtat ttgctcagct atcagcgcga gcagatgaga accatgactt tttctcagga
     1201 aatggctctt cttacgtgat gggagttact gaggaaacca ttgatgatga ttgggagttt
     1261 taagatggct gcaagggtaa tgcttgttta tttttcatcg cgatctaaca acactcaccg
     1321 ctttgtgcaa aagctagatg taagagctct aagaattcca gtcactggtg agcctctatt
     1381 agttgatgag gattatattt tgattgtccc tacctatgct gctggtggct cagacagcaa
     1441 gggagctgtt cccaagcagg tgattcattt tctaaacaag gctaacaatc gaaggcactg
     1501 taagggggtt atttcctctg gcaatactaa ctttggtgat acctttgcca ttgcaggacc
     1561 aatcattgca caaaaattgc aggtgccgct tttgcaccaa tttgaattgc tggggacaca
     1621 aagagatgtc atcaaggtgc aggctatttt agcaggtgat gaagccttat aactaatgat
     1681 agaaaaacga tcacacattg taacgaaagg aaaaaagaat gtcacaaaaa gagtcctacc
     1741 tctcattaaa tgcccttaca cgctttaaac gagcagatgg tacctatcac tttgacagtg
     1801 ataaggaagc tgttcagcgc tatttagagg agcatgtcta cccacaaagc ctatcctttg
     1861 atagtttgga ggagaaatgg cgttatttgg tggcgcatga ttattatgat caagagattt
     1921 taaaggctta ttcggctgaa tgtatcactg aagcctttac ctacgcttac cagcaaaagt
     1981 tctcattttt gagcttaatg ggagccatga aattttacca gtcctatgcg cttaaaaccc
     2041 tagatgggtc acaataccta gagcattttg aggatcgtgc tgttatgaat gccttgtttt
     2101 tggctaatgg tgatcctgat ttggtgcggg atttgattga tcagatactt agcgggcgct
     2161 ttcaaccggc gacccctacc tttttaaatg caggtaaaaa gcgtcgaggc gaatatattt
     2221 cctgttattt gctgcgaatc gaagacaaca tggaatctat ttcgcgtgcg attggtacga
     2281 gcttgcagct ctcaaaacga ggcggcggcg ttgctttgtg tttaaccaat ctaagagagg
     2341 ttggctctcc cataaaaggc attgaaaatc aagcgacagg cattgtgcca gtgatgaagc
     2401 tactggagga ttccttttcc tatgccaatc agctagggca aagacaggga gcaggtgcgg
     2461 tttacctcaa tgtgcatcac ccagagattc tgaccttttt agatacgaag agagaaaatg
     2521 cagacgaaaa aatccgtatc aagtcactgg cgttaggcgt tgtcattcct gatattacct
     2581 ttcagctggc gcgggaaaat aaggacatgg cgctattttc tccctatgac attaagcgag
     2641 tttatggcaa ggacatgtca gatattgcca ttaccgagga gtatgaccgc ctagtggcca
     2701 acccagccat taaaaagacc tatatcagtg cccgtaagct ctttcagctt attgcagagc
     2761 ttcattttga atctggctac ccttatctct tgtttgatga tacggttaat aagcgcaatc
     2821 cacacccaca aaaggggcgg attgtcatgt caaacctttg ctctgaaatc gctcaggtca
     2881 gcacagcaag cacctttgaa gaggatttga cctttaagca aatcggcgag gacatttgct
     2941 gtaaccttgg ctctattaat attgctgaag ccatgaagca tgcggttggc tttgagcaat
     3001 tgattgcaac tagtgttagg gccttggacc atgtgtcaag ggcctcagac gtcagctgcg
     3061 ctccttctgt tgaaaagggg aatgctgcta atcatgctgt tggtcttggc gcgatgaatt
     3121 tacatggctt tttggcgacc aatcacatct tttatgattc agctgaagca gtagatttta
     3181 ctgatctctt tttccacaca atggcctatt atgcctttaa ggcttctagt caattagcta
     3241 aggaaaaggg agcatttgct ggctttgagc agtcaaccta tgcagatggc agctactttg
     3301 cccgctattt gacaaaagag gctaagccta agacagctaa ggttgcggcc ttgcttgagc
     3361 gctacgggct tcgagtgcct agtgtggctg attggcagga attagttgcg acgattcaag
     3421 agacaggcct tgccaatgct cacttgatgg cagttgcacc aaccggctcg atcagctact
     3481 tgtcctcatg tacgccgagc ttacagcctg ttgttgcacc agttgaggtg cgaaaggagg
     3541 ggcacttagg aaggatttat gtgcctgctt atcagataag cgatgataac tatgcttatt
     3601 acgagcgtgg tgcctatgag gttgggcctg agcctattat taatatcgta gcagcggctc
     3661 aaaagcacgt tgatcaggca atttccttaa ccctatttat gacagaccaa gcaacaacac
     3721 gtgatctcaa ccgtgcctat atacacgcct ttaagttaaa gtgtgcgtcc atttattatg
     3781 ttcgcgtcag acaggacgtt ctggaaggaa gtgagcagta tgaggaagat acgattgtag
     3841 cgcttaccga taccaatgct tcaggcgagg catgccaatc ctgcatgctt tagatctttt
     3901 ttagccttaa aaataggcag caccaatcag ccttcatgct ctgtctagcc agtttgttaa
     3961 taggcttata gtatcgcttg atccaacagg ctgatggcaa gctctcttga gcttaatgca
     4021 gctcagcctg atttgtgatc aatgcttgct gacaagcccc ttgtcaaatg aagtgggcta
     4081 ccggtgcttg ttgtaaggac atttggcttg gataagccaa tgcttgctga tttgcttaag
     4141 gagaatcaag aaaaaagctc cctcttcaat cgataattac tggggcttgt ctccgtgtta
     4201 atcactggga tttcttgtaa ctgtcaaaac aatcagaaga ttcaaaataa cctatagtat
     4261 ttctaaaata tt
//
LOCUS       DARYXS010000115         4222 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.116, whole genome shotgun sequence.
ACCESSION   DARYXS010000115 DARYXS010000000
VERSION     DARYXS010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4222
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.116"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            11..337
                     /locus_tag="TV193_001766"
     CDS             11..337
                     /locus_tag="TV193_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEL1513930.1"
                     /translation="MYFPVSATLIEFLILSIVDKHDSYGYDISQTIKLVANIRESTLY
                     PILKKLEKSDYLTTYSQEHQGRKRNYYTITAKGEKQLIFLKEEWQSYKATLDGIIEGR
                     LRHDKR"
     gene            324..749
                     /locus_tag="TV193_001767"
     CDS             324..749
                     /locus_tag="TV193_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513931.1"
                     /translation="MTRDEYLAELDKYLRKLPKADYYEAAENSSQLELNDGSIKDSSI
                     TVADTKEENDYDYTDPSELAINHVTIKEKNTINGGDININTTLANPRDIAYHVTTRGN
                     IKLSSRFSNAKLNTDAATGATSFHSDIANTVNQSDLSIH"
     gene            768..1823
                     /locus_tag="TV193_001768"
     CDS             768..1823
                     /locus_tag="TV193_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL1513932.1"
                     /translation="MTKQDFLDKLKQQINHLPQKDYQEIIDHFTEYFDEAGPDHEQAI
                     LKELGNPEDIAKELLKALDLPEKTDEDDWTNWEVDNKTKSEASSQKLEPIVDIRYSLL
                     NHDLTIETADIPYPTISYDDNRITISQDSDGMLNIIEDSAVQTIQYGFHFLDRWLAKY
                     QPITLTLPVNHHLKKISGESDNNDVTIRHIHCDSIVSNTYNGTISISHLSDSTVNLSS
                     KNGNIILEHCNIQSSKCQAKNANLSCDNSTLINCQLNNNNGNIRLEASQLTETFIENK
                     NGNIIGQQLSFSNDITIINKNGIIDINCPRENLIYYDVKASNNNGFVTISQEAGRQTP
                     FKAQLTISNNNGLISVS"
     gene            complement(1927..4209)
                     /locus_tag="TV193_001769"
     CDS             complement(1927..4209)
                     /locus_tag="TV193_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEL1513933.1"
                     /translation="MLEGLKAIIKNRKLVVTMIGVALVPALYNLSFLGSMWDPYGRVD
                     QLPVAVVNQDKPAYLNNKRLTIGNDMVDNMSKNKELDYHFVAADTAQKGLEKGRYYMT
                     ITLPKDLSQKATTLLDQQPEKLIVSYQTSKGHSFIASKMGESAMNHLREAVSKNIRKT
                     YITSVFKSMHQLQSGLKEASNGGQQLAAGLVIARASSQLMSRHLNTLSESSARLSQGA
                     GNLSSGIAAYTAGVGQLDTAGLGQLAADMPAYLDGVSRLSKGANQLNAGLTQLALGSD
                     LSQDKQANIQALMASLPKLNQAIQQLKTNLSLSLAPNVDSGAIAKHLADMTRLVQELV
                     VDDTADKNNQLAALQATATYQGLNSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSE
                     ELEAMSTSAGVADQLRDFKALVNQLAYQADQILPSTGKALSELSTGLRAVHSATTAQL
                     LSGSQALAGGFNQLTAKNEALTAGLSTLATGATALNHQSSQLLAGGQQLTVGANQLAF
                     GANQLSSGSSQLTDGLTTLSTGLSSLTTSLSKASDQLSMAWVEDQNADMVSDPVALSE
                     KDKDKVRTNGIGMAPYMIAVSLMVVALSTNIIFAEALSGKPIKDRWDWAKQKLLINGM
                     ISTVGSVILYAALQLLGFEANDGIKTLGFIMLSGWALMALVTALVSWDARYGAFASLI
                     MLLLQVGAAGGSYPIELSGQIFQILHPYLPMSYIVSGLRQTISLTAQIGLETSVLVGF
                     LLSFMAIGVLIYRPKDKQSS"
BASE COUNT         1372 a          956 c          783 g         1111 t
ORIGIN      
        1 gagtaaccag atgtattttc cagtatctgc taccttgatt gaatttttga ttttatctat
       61 tgtcgacaag catgattcct atggttatga tatcagccaa accattaagc ttgtcgctaa
      121 tatcagggaa tcaaccctat accctatttt aaaaaagcta gagaaatcag actatttaac
      181 tacctatagt caggaacatc aaggtcgcaa gcgtaactat tacaccatta cagccaaagg
      241 cgaaaagcag ctgattttct taaaggaaga atggcaaagc tacaaggcca ccctagatgg
      301 cattattgaa gggagattaa ggcatgacaa gagatgaata cctagcagag ctagacaaat
      361 acctacgaaa attacctaaa gcagattatt atgaagctgc tgagaactca agtcagctag
      421 aacttaacga cggcagtatc aaagactctt ctatcactgt agctgataca aaagaagaaa
      481 acgactatga ctatacagac ccctccgagc ttgctataaa tcatgtcaca atcaaggaga
      541 aaaacacaat taatggcggc gatattaata tcaataccac attagcaaat ccaagagata
      601 ttgcttatca tgtcacaaca agaggcaaca tcaagctcag ctctcgtttt tcaaacgcca
      661 agcttaacac agacgcagca acaggagcta cttcatttca ctctgacata gccaatactg
      721 tcaatcaaag cgacctatca attcattaat caagggagga tatcataatg actaaacaag
      781 attttctaga caagctaaag cagcagatca accatttacc tcaaaaggat taccaagaaa
      841 tcattgacca ttttacagag tattttgacg aggctggtcc tgaccatgaa caagctattc
      901 ttaaagaact gggaaatcca gaggacattg ccaaggagct attaaaagcc ttagatctcc
      961 ccgaaaaaac agacgaagat gactggacga attgggaagt tgacaacaaa acaaagtcag
     1021 aagcaagctc acaaaagctt gagccaatag ttgacattcg ctatagtctg cttaaccatg
     1081 atttaaccat tgaaactgct gacattcctt accctactat ttcatacgat gataatcgca
     1141 tcacaataag ccaagatagt gacggcatgc tcaatatcat tgaagactca gcagtacaaa
     1201 caatacagta tggctttcat ttcctagacc gctggcttgc aaaatatcaa cccattacct
     1261 tgacactacc tgtcaaccac cacctgaaaa aaatctctgg agaaagtgac aacaacgatg
     1321 tcaccataag gcatatacat tgtgatagca ttgtctctaa cacttacaat ggaacgattt
     1381 ctatcagtca tttatcagat agcactgtca acctaagcag caaaaatggg aacattattt
     1441 tagagcattg caatatccag tctagtaaat gtcaagccaa aaatgctaac ctcagctgtg
     1501 acaatagcac cctaataaat tgccagctga acaataacaa tggaaacatc agattagaag
     1561 caagtcagct aacagaaacc ttcattgaaa acaaaaacgg taatatcata gggcagcagc
     1621 tgtccttttc caatgacatc actatcatca ataagaatgg aatcattgac atcaattgtc
     1681 ctagagaaaa cctcatctac tatgacgtaa aggcttcaaa taataatgga tttgtaacga
     1741 ttagtcaaga agcaggtcgt caaacaccct ttaaagcaca gcttaccatt tccaataata
     1801 atggtcttat ctccgtaagc taaaccaacc ataaaaaaag cttctagaaa gagcttaaac
     1861 cacaatttct agaagctttt ttattatatc tactgtttaa cgataacctg ttatctcagc
     1921 tattatctag gacgattgct tgtcctttgg acgataaatc agcactccta tagccataaa
     1981 gcttaacaaa aagccaacta atacactcgt ctctaaacct atctgggcag ttaatgatat
     2041 tgtctgacga aggccagaga caatataaga cattggaaga taaggatgga gaatctggaa
     2101 gatctgacca ctcaactcaa taggataaga accacccgca gcaccaacct gtagcaacag
     2161 cataattaac gaagcaaagg caccatatcg agcatcccag ctgaccaatg cagtcactaa
     2221 agccatcaag gcccatccac tcagcataat aaagcctaag gtcttgatac cgtcattagc
     2281 ttcaaagccc agcagttgaa gtgcagcgta aagaataaca gagccaacgg tcgaaatcat
     2341 gccattgatc agtaattttt gctttgccca atcccatcta tctttaatcg gcttaccaga
     2401 taaggcctct gcaaaaataa tatttgtaga caaggcaact accattagag acacagcaat
     2461 catataagga gccatgccaa taccattggt cctaacctta tccttgtcct tctctgataa
     2521 cgctactgga tcagatacca tatcagcatt ctggtcctct acccaagcca ttgaaagctg
     2581 gtcagaagct tttgatagtg aggtcgttaa gcttgacaga cctgttgaca gagttgtcaa
     2641 gccatctgtc aactgagagc tgccagagga gagctgattg gctccaaaag ctagctgatt
     2701 agcgcctact gtaagctgct gtccacctgc taataattga ctggattgat ggttaagagc
     2761 tgttgcccct gtagcaagag tagacaggcc tgctgtaaga gcttcattct tagctgtcaa
     2821 ttgattaaag ccgccagcaa gagcttgact acctgataag agctgggctg ttgtcgctga
     2881 gtgaacagcc cttaaaccag ttgaaagctc tgacaatgcc ttgcctgtgc taggtaggat
     2941 ttgatcagct tgataagcca gctgattaac aagtgcttta aagtccctca gttgatcagc
     3001 tacaccagca cttgttgaca tagcctctag ctcctcagac atggcttgca gtgatgtcaa
     3061 catagccttt gctgatattg ttactttagt tgaagtattg gaaatagctg agctcagctc
     3121 ctcctgctgc tcagagttga gaccttgata ggtagctgta gcttgtagag cggctagctg
     3181 attgttcttg tcagcagtat catctaccac aagctcctgc actaaacgcg tcatatcggc
     3241 taaatgctta gcaatggctc ctgagtccac atttggtgcc aaagacaagg aaagattggt
     3301 ctttagctgc tggatagcct gattaagctt tggtaggcta gccattaaag cttgaatatt
     3361 agcttgtttg tcttgagaca gatcacttcc tagagccaat tgggtcaagc cagcatttaa
     3421 ctgattagca cccttggata accgagaaac accatctaga tacgctggca tatcagctgc
     3481 tagctgtcct aagcccgcgg tatcaagctg accaacaccg gctgtatagg cagctatacc
     3541 actagataga ttacccgctc cttgagacaa gcgagcactt gattcagaca aggtgttcaa
     3601 atgccttgac attagctgac tgcttgccct agcaattact aagccagcgg ctaattgctg
     3661 accgccattt gaagcttcct ttagaccaga ttggagctga tgcatgctct taaaaacgga
     3721 ggtgatatag gtcttcctta tatttttaga aacagcctct ctcaagtgat tcatagcaga
     3781 ttcacccatt ttagaagcga taaagctatg gcccttacta gtttgatagc taacaatcag
     3841 cttctctggc tgctgatcta atagcgtagt ggccttttgt gacaaatcct ttggcaacgt
     3901 aatcgtcata taataacgac ccttttccaa gcccttttgt gcggtatctg cagccacaaa
     3961 atgataatcc aattccttat ttttagacat attgtctacc atatcgttac caatagtcag
     4021 tctcttgtta ttcaagtaag caggcttatc ctgattcaca actgctacag gcaactgatc
     4081 aacccgacca taaggatccc acatggaccc taaaaaggac aaattataga gagctggtac
     4141 tagagcaacc ccaatcattg tcactactag cttacgattt ttgattattg cttttaatcc
     4201 ttctagcatt attttttctc ca
//
LOCUS       DARYXS010000116         4197 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.117, whole genome shotgun sequence.
ACCESSION   DARYXS010000116 DARYXS010000000
VERSION     DARYXS010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4197
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.117"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            173..400
                     /locus_tag="TV193_001770"
     CDS             173..400
                     /locus_tag="TV193_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513934.1"
                     /translation="MTKDDFLTGFVLILLAACIFAVGFAIGHDYSSEHYEQKITDLQI
                     QLVSTQQQLKQSREQNQSQTKRIANLTGNGG"
     gene            411..1100
                     /locus_tag="TV193_001771"
     CDS             411..1100
                     /locus_tag="TV193_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1513935.1"
                     /translation="MEIKCGNCLELLTELTDGSIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGADLLSWIDIASRKLTKNGGMVIFNDWKNLGDIARHCEKTGLAVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGIWVVRKNSKWVFNRKSEKYDRPEYRYPIVSGAEKTQH
                     PTQKPVALMRDIITRHTTKRAVVLDPFMGSGSTGVACLLTERDFIGYELNKDYFNIAN
                     KRIAELTGNGG"
     gene            1102..1893
                     /locus_tag="TV193_001772"
     CDS             1102..1893
                     /locus_tag="TV193_001772"
                     /inference="COORDINATES: protein motif:HMM:TIGR00675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEL1513936.1"
                     /translation="MLRVFEAFAGIGTQRMALRNLGIPHEVVAIAEIDKFAIKSYEAI
                     HGPVNNLGDISKINPDTIPDHDLFTYSFPCQDISVAGKQAGLDIDSGTRSGLLWECQK
                     VIVAKKPKYLLMENVKNLVGKKHKPNFDKWLDWLESQGYTNDWQVLNAKDYGVPQNRE
                     RVFCVSILGEHKPYIFPEKQELTIRLKDILEDDVDEKYYLTTNKANELLATIVRENDV
                     SERVVVDSTIKKPKIKNVMNAVIGRYDAGIRNQQSVGGAVIELIE"
     gene            1877..2380
                     /locus_tag="TV193_001773"
     CDS             1877..2380
                     /locus_tag="TV193_001773"
                     /inference="COORDINATES: protein motif:HMM:NF012372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEL1513937.1"
                     /translation="MSLLNKNATKKGYLVADDGDGIDTAYPDSKTRKGRVQKNMSHTI
                     TTDDSKAFLIGASRGRDPENPNDRSAGNQNLQQRLEINKNGTSNTITSVQKDNYAVEF
                     PDYRIRKLTPLECWRLMGCSDEDFEKAQSVNSNSQLYKQAGNAIVVDVLEAILKQLFL
                     TEAQNEH"
     gene            2370..2888
                     /locus_tag="TV193_001774"
     CDS             2370..2888
                     /locus_tag="TV193_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1513938.1"
                     /translation="MNIEEAKQKLHNMAYRDLQTKPYDLKLADVIQILNQIKLDKPQP
                     EIPQFVADYIDDMHKNARTLRYAFKYMESNIKMHKWCVFEKQETFVNAFLYGYTIEKE
                     KLYTVEIPNPKNGIAHRHIMLVKTTDGRVVLSEVVDSHIHLRDDLRLTESEIRKDFDW
                     AWREEFPKEVTE"
     gene            2915..3214
                     /locus_tag="TV193_001775"
     CDS             2915..3214
                     /locus_tag="TV193_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513939.1"
                     /translation="MNYDKKKSDLKKRLIIGFTLLPISIVLSGFVIKYGWNNILSTID
                     GVPPINLPQAIAIDVLVSFIIAKTNAEGDFATEVGRAFISPLMTLLLFWVVTLFM"
     gene            3231..3404
                     /locus_tag="TV193_001776"
     CDS             3231..3404
                     /locus_tag="TV193_001776"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513940.1"
                     /translation="MTEELGVLLDKEGVEYVKMVFDDGFVWTIRNPLNAALLKRQDAE
                     QFPQFTWVPLTDL"
     gene            3741..4181
                     /locus_tag="TV193_001777"
     CDS             3741..4181
                     /locus_tag="TV193_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL1513941.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVPSKPVERLALNRVSAEQELDAIERAVNGIFDPEYRLILIDKYLLTYPKTD
                     CDIYTKLGYEKSQYYNMLDNALMSFSELYKEGMLLVEKMEKSWN"
BASE COUNT         1475 a          688 c          943 g         1091 t
ORIGIN      
        1 ttagtttatt ttgacaatat gttggacgaa gaatataagt ttaaaacaga aaaagatgca
       61 tcgaaatgcc atgatcaatt gcgaaggaaa taccaaggtc agcgtttata taaggtaaaa
      121 atggaggagg tggaagaaga ggtaatcata actaacttca gggaggttga tcatgactaa
      181 agacgacttt ttaacaggtt ttgtacttat acttttagct gcttgcattt ttgctgtggg
      241 atttgcgatt gggcatgatt atagcagtga gcactacgag caaaaaatca cagatttaca
      301 aatacagctg gtaagcacgc agcagcagct taagcaatct cgtgagcaaa atcagagcca
      361 gactaaaagg attgcgaatc tgaccgggaa tggaggataa aaaacactac atggaaataa
      421 aatgtggaaa ttgcttagaa ttactaacag agttaactga tggatcaatt gatatggtga
      481 taacagaccc gccatataac atatcagtaa aaaataactt tgctacaatg gggcggacag
      541 gtatagattt tggtgattgg gataaaggtg cggacttatt aagttggatt gatattgcaa
      601 gtcgaaaatt aactaaaaat ggtggaatgg tgatctttaa tgattggaaa aatttaggag
      661 atattgcaag acattgcgaa aaaacaggct tagcagtaaa agatattttc cgttgggtaa
      721 aagataaccc tatgccaaga aatcgagata ggagatacat tacagatagc gagtacggga
      781 tatgggtcgt ccgaaaaaat tccaagtggg tatttaatcg taaatcggaa aaatatgata
      841 ggccagaata tcgctatcct attgtatcag gagcagagaa aacacagcac cctactcaaa
      901 agccggtagc cctgatgagg gacatcatta cgcgacacac aacaaaaagg gctgttgttt
      961 tagacccttt tatgggcagc ggatcaactg gagtagcttg tctactgacg gagagagact
     1021 ttattggata tgagctaaat aaagattact ttaatatcgc aaacaaaagg attgctgagt
     1081 tgactgggaa tggtggatga gatgttaaga gtatttgaag cttttgcagg tattggtacg
     1141 caacgcatgg cattgcgaaa cctcgggata ccacacgaag tagtagctat tgccgagatc
     1201 gacaaatttg ccattaaaag ttatgaggca attcatggcc cagtaaataa tctaggtgat
     1261 attagcaaga ttaatcctga cactattcct gatcacgact tatttactta tagctttcct
     1321 tgtcaagaca tttctgtggc agggaagcaa gctggtcttg atattgatag cggtacacgc
     1381 tcaggattgc tctgggaatg ccaaaaagtt atagtggcta aaaaaccgaa atatctatta
     1441 atggaaaatg taaaaaatct cgtaggcaaa aagcataagc caaattttga taaatggctt
     1501 gattggctag agagtcaagg ctacacgaat gactggcaag tgctaaatgc aaaggattac
     1561 ggtgtcccgc aaaatagaga gcgtgtgttt tgtgtgtcga ttttaggtga gcataaacct
     1621 tatattttcc cagaaaaaca ggaattgacc atcagactaa aggacatttt ggaagatgat
     1681 gttgatgaaa agtattattt aacaacaaac aaagcaaatg aattattggc cacgattgtc
     1741 cgagaaaatg atgtttctga aagagttgtt gtagatagta cgataaaaaa accaaaaata
     1801 aaaaatgtaa tgaacgctgt aataggaaga tatgatgcag gcatccgaaa tcaacaatcg
     1861 gttggaggtg ctgtcattga gcttattgaa taaaaatgca acaaaaaaag gctacttagt
     1921 agccgatgat ggggacggaa tagatactgc ttatccagat agcaaaacga ggaaagggag
     1981 agtgcaaaaa aacatgagcc atacgataac gacagatgat agtaaggcct ttttgattgg
     2041 cgcaagtcgt gggagagacc ccgaaaaccc aaacgatagg tcagctggaa accaaaacct
     2101 acaacaaaga cttgaaatca acaaaaatgg cacaagcaat acaattacaa gtgtccaaaa
     2161 agataactat gcggttgaat tcccagatta ccgcatccgc aagctaacac cgctagaatg
     2221 ttggcggttg atggggtgta gtgatgagga ttttgaaaaa gcacagtctg tcaatagcaa
     2281 tagtcagctt tacaaacagg caggaaacgc aattgtggtt gatgtgctag aggcaatatt
     2341 aaagcaatta tttttaaccg aggcgcaaaa tgaacattga agaagcgaag caaaaattac
     2401 ataacatggc atatagagat ttacaaacta agccgtatga tttgaaactt gctgatgtta
     2461 ttcagattct taatcaaatt aaactcgaca aacctcaacc agaaattcca cagtttgtcg
     2521 ctgactacat agatgatatg cacaaaaacg cacgtacatt gagatacgct tttaaataca
     2581 tggaaagtaa cataaaaatg cacaaatggt gtgttttcga aaagcaagaa acgtttgtta
     2641 atgctttttt atacggatat acaattgaaa aagagaaact gtacactgtt gagataccaa
     2701 atccgaaaaa cggtattgcg cataggcaca taatgctggt taagacaact gacggaagag
     2761 tagttttgtc tgaagtagta gactcacaca tacatttgag agatgattta agactcaccg
     2821 agtcagaaat ccgcaaagac ttcgattggg cttggagaga ggagtttcct aaagaggtga
     2881 cggaatgatg aatgaaagag aattaaataa attgatgaat tacgacaaaa agaaaagtga
     2941 tttaaaaaaa cgcctgatta taggatttac cctattgcca atcagcatcg tattgtctgg
     3001 atttgttatt aaatacggtt ggaataatat tttgtcaaca attgatggcg tcccacctat
     3061 caatttacca caagcgatag caattgatgt gctagtaagt tttatcattg ccaagacaaa
     3121 cgcagaagga gattttgcca cagaagttgg cagagctttt atttcgccgt taatgacgtt
     3181 gttattgttt tgggtagtga ctttgtttat gtaatgttta gaggtaacag atgactgaag
     3241 aattaggagt gttgcttgac aaggaaggag ttgaatacgt aaaaatggta tttgatgatg
     3301 gctttgtctg gacgatacgc aacccactaa acgctgcgtt gcttaaacgc caagatgcag
     3361 agcagttccc gcagtttacg tgggtgccac tgacagattt ataaccccac gcaatggctc
     3421 tgtgggatta cgtgccagga accacgttga aagcgactta gacaccttca tttttatcag
     3481 ccttgcggat tgtcaaaggt tcgtaaggtg tagaccgaaa ttaaacacag aaggatgtga
     3541 tgacaatctc cttacaccca aaaaatctaa cgctggttac cggtcaccag ctattatcca
     3601 aggcgctaat actgacatcg tgcgcctgtg tcaaaataaa aaaaggaaga gagggctttt
     3661 ctccacaaaa aaagacgtcc atgcgaacgc ctccttggtt atatctgtta acaccattat
     3721 accacactga gggggctttt atgacgtttt ttcccgagat tgatatccaa aaaacaaaat
     3781 ccaatgccaa gcgtaaattg aaagagtatc cacgctggcg gcggatagct aacgatgtag
     3841 atactcaaaa agttacagct acttactcat ttgagccaag gcaacctcat ggagtcccta
     3901 gcaagcctgt tgagagacta gcacttaatc gtgtatcagc ggaacaggaa ctggatgcga
     3961 ttgagagagc ggtcaacggg atatttgatc cagagtatag attgatactg attgacaagt
     4021 atttgctcac atatccaaag actgattgtg atatttatac aaaacttggt tacgagaaaa
     4081 gtcagtacta caacatgcta gataatgctt taatgtcttt ttctgaacta tacaaagagg
     4141 ggatgttgct tgtcgaaaaa atggaaaaaa gctggaatta atatggaata attatgt
//
LOCUS       DARYXS010000117         4170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.118, whole genome shotgun sequence.
ACCESSION   DARYXS010000117 DARYXS010000000
VERSION     DARYXS010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.118"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(121..1791)
                     /locus_tag="TV193_001778"
     CDS             complement(121..1791)
                     /locus_tag="TV193_001778"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEL1513942.1"
                     /translation="MKSDIEIAQSVPLKPITEIVKKVGIDADDLELYGNYKAKLSFEK
                     IKSVEDNKPGKLILVTAINPTPAGEGKSTMSIGLADALTKIGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTAHNALSALIDNHLQQGNELGIDPRR
                     IIWKRVLDLNDRSLRQVIVGLGSPVNGVPREDGFDITVASEVMAILCLATDLKDLKAR
                     LANIVIAYRYDKSPVYVRDLKVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKTPNLPKAPDAVVIVATLRAL
                     KMHGGVAKADLTFENTAAVRSGFANLKRHVENIRKFNIPIVVAINEFVTDTKAEIQVL
                     KELCAEIAVPVELASVWAKGADGGIALANAVVKAITEESAAYKRLYADKDSLEEKLKA
                     IVTEIYGGRAVQFGPKAKNQLKQFAQFGWDQLPVCMAKTQYSFSDDPSLLGAPDQFDI
                     TIRELVPKTGAGFIVALTGDVMTMPGLPKIPAAMKMDVTEDGTAVGLF"
     gene            1989..2681
                     /locus_tag="TV193_001779"
     CDS             1989..2681
                     /locus_tag="TV193_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEL1513943.1"
                     /translation="MAMKLLITSGGTTEAIDAVRGITNHSTGQLGKIVAETFLAKGFD
                     VTLVTTKTSVKPAQQPHLTIREVTNVDQLMAILKEEVPKHDLLIHSMAVSDYSPVYMT
                     DFDTVAAADHLQTFLTASNKEAKISSAADYQVLFLKKTPKVISYIKEWNPNIRLVGFK
                     LLVNAPAEELISVARDSLHKNKADYIVANDLADIKANQHKAFLVNDKTVCSASTKEEL
                     AQLIYERIIAND"
     gene            2674..3219
                     /gene="coaC"
                     /locus_tag="TV193_001780"
     CDS             2674..3219
                     /gene="coaC"
                     /locus_tag="TV193_001780"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEL1513944.1"
                     /translation="MTKRITLAVSGSISAYKAADLTSQLTKKGYEVTVLMTQAATAFI
                     TPLTLQVLSKNPVHLDVMAEHDVKIVNHIELAKATDLFVLAPASANTIAHLAYGFADN
                     MVTSVALALPEATPKLIAPAMNTNMYLNPITQGNIKRLADLGFREIPPKTALLACGDR
                     GPGALADIDDMVTAISQQLAR"
     gene            3276..3848
                     /locus_tag="TV193_001781"
     CDS             3276..3848
                     /locus_tag="TV193_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1513945.1"
                     /translation="MNHNKSSEISRIAIFFAVMLVIHFISSWFFYIWPVPIKPTLVHI
                     PVIVASIMYGPRTGAILGGLMGIVSVITNTLVLLPTSHLFSPFVTNGNLASLMIAMLP
                     RILIGITPYYCYKLIKNELGLVLAGLVGSLTNTIFVLSGIFIFFPTASGDNVKTFLTT
                     IVSGNAITEMIVSAIVTITLIPALSKLKKS"
BASE COUNT         1225 a          941 c          785 g         1219 t
ORIGIN      
        1 acgattaaaa tagtaaaata tgagctattg ttatcagctt atccttagac attaaaaaag
       61 attgaagaaa ccccctttct gaagctttct tcaatcctga ttctggctat aacaaataaa
      121 tcaaaacaat cctactgctg taccgtcttc ggtgacgtcc atcttcatag ctgcaggaat
      181 ctttggcaag cctggcattg tcatcacatc tccagttaag gcgacgataa agccggcacc
      241 ggtcttaggc actaattcac gaatggtaat gtcaaactga tctggcgcgc ctaggagcga
      301 tggatcgtct gaaaagctat actgggtttt ggccatgcaa acaggcaatt gatcccaacc
      361 aaactgggca aattgcttga gctgattttt agctttaggt ccgaattgca cagccctacc
      421 accataaatt tcagtcacaa ttgccttaag tttctcctct aagctatcct tgtctgcata
      481 tagacgctta taggctgcgc tttcctctgt aatagccttg acaacagcgt tggcaagagc
      541 aataccgcca tcagccccct tggcccacac gcttgccaat tcaaccggaa cagctatttc
      601 tgcacacaat tcttttaaga cttgaatttc tgctttagta tctgtcacaa attcgttgat
      661 agctacaaca atcggaatat tgaattttcg aatattctca acatgacgct ttaaattagc
      721 aaagccagac cggaccgcag ctgtattttc aaaggttaaa tccgccttag caacaccgcc
      781 atgcatcttc aaggcacgaa gtgttgcgac aataacaact gcatcaggag ccttaggtag
      841 attcggtgtt ttgatgttaa ggaatttttc tgctccaaga tccgctccaa agcctgcctc
      901 tgtaacagta taatctgcca accgcaaagc tgttgatgtc gccagaacag aattacagcc
      961 atgagcaata ttggcaaagg gtccaccatg cacaaaggct ggtgtaccat agattgtttg
     1021 aacaaggtta ggcttgatgg cgtccttcaa aatcaaggct aatgcccctt ctacctttaa
     1081 atcacgcaca tatacaggtg atttatcgta acgataggca atcacaatat tagctaaacg
     1141 agccttcaag tccttaagat cagtcgccaa gcaaaggata gccatcactt cagaggctac
     1201 tgtaatatca aaaccgtctt ctcttgggac accattgaca ggactcccca agccaacaat
     1261 gacctgccta agagaacggt cattcaaatc aaggacacgc ttccagatga tacgacgcgg
     1321 gtcaatacca agctcattgc cctgctgaag gtgattatca ataagggctg ataaagcatt
     1381 atgagctgtg gtaatagcat gcatgtcccc ggtaaaatga aggttaatat cttccatcgg
     1441 aagaacctga gcgtagccgc cacctgcagc accacctttg atccccataa ccggtcctaa
     1501 agagggctca cgcaaggcca gcatggtttt tttaccgatt ttagtcaagg catctgccaa
     1561 accaatagac atggttgatt tgccttcacc tgctggcgtt ggattaatag cagtcactaa
     1621 aatgagctta ccaggcttat tgtcctctac tgatttgatt ttttcaaagg ataatttggc
     1681 tttgtagtta ccgtaaagct ccaaatcatc agcatcaatc cccacctttt taacgatttc
     1741 tgtaatcggc tttaagggga cactttgagc aatttcgata tctgatttca tgaaaactcc
     1801 ttgactctta cttgatagtg ttattatatc acacttcatc tcaaacgtac attgatttgt
     1861 tctatataca aaaatgttcg tttttataat ggttctgaaa ggaaaaaagc ttagtagcgt
     1921 cagcattgtc agtaaaaata attttaatta gtgattttat ttactattct tgctttttct
     1981 gataaaatat ggctatgaaa ttattaatca catcaggcgg aacgaccgaa gcaatagacg
     2041 ccgttagagg gattaccaat cattccactg gccagctagg aaagatagta gctgagacct
     2101 ttctagcaaa gggatttgac gttactctag tgacaacaaa aacttcagta aaaccagcac
     2161 agcagcctca tttgaccatt cgtgaggtga ccaatgttga tcagctgatg gctatcttaa
     2221 aagaggaggt tcctaagcac gaccttctca ttcacagcat ggctgtttca gattatagcc
     2281 cagtgtacat gacagacttt gatacagttg cagctgctga tcatttacag acctttttaa
     2341 cagcaagcaa taaggaagcc aaaatctcat cggcagctga ttatcaggtg ctctttctta
     2401 aaaaaacacc taaagtcata tcctatatta aggaatggaa tcctaatata aggctagtcg
     2461 gctttaagct attggtcaat gctccagctg aggagctaat ttcagtggca cgagatagcc
     2521 tgcataaaaa caaagcagac tatatagtag ccaatgacct agcagatatt aaggccaatc
     2581 agcacaaggc ttttcttgtc aatgacaaaa cagtctgctc tgccagcacc aaagaggagc
     2641 ttgcacaatt aatctatgaa aggataatag ccaatgacta agcgaataac acttgcggtc
     2701 tcaggtagta tttctgccta taaggcagct gatctcacca gccaattaac caaaaaaggc
     2761 tatgaggtta ctgtgttgat gacgcaagca gctactgcct ttatcactcc gttgacccta
     2821 caggtcttat cgaaaaatcc tgtccatcta gatgtcatgg cagagcacga tgtcaaaatt
     2881 gtcaatcata ttgagctagc taaagcaaca gatctatttg tccttgctcc tgcaagtgcc
     2941 aataccattg ctcatttagc ctacggcttt gctgataata tggttaccag tgtcgcccta
     3001 gccctgcctg aggcaacacc caaactcatc gctcctgcta tgaatactaa catgtacctt
     3061 aacccaatta ctcagggaaa catcaaacgc ttagctgatc ttggctttcg agaaatacca
     3121 cctaagacag cactccttgc ctgcggcgac agaggacctg gggccttagc agatattgat
     3181 gatatggtta cagcaattag tcagcagcta gcaagatagc tggtcaccga ttagcaattg
     3241 ctgtattata atataaaaat ttaatggaga atgcaatgaa tcataacaaa tcttctgaaa
     3301 tctctcgtat tgccatcttt tttgcagtca tgctggttat tcacttcatt agtagctggt
     3361 ttttttatat ctggcctgtc ccaattaaac caacactcgt ccatattcca gttattgttg
     3421 cttctatcat gtatggtccg cgcactggag ctatcttagg aggcttgatg gggattgtca
     3481 gtgtgatcac aaataccttg gttttacttc caacaagcca tcttttctca ccatttgtca
     3541 caaatggtaa tctggcttcc ttgatgatcg ctatgctgcc tcgtatcctg attgggatca
     3601 ctccttatta ctgttataag cttatcaaaa acgagcttgg gcttgtccta gctggtcttg
     3661 ttggctcgct gacaaacacc atttttgttc tctcaggaat atttatcttt ttcccaacag
     3721 cctctggtga caatgtcaaa acgtttctaa ctaccattgt atctggcaat gctattactg
     3781 aaatgattgt ttcagctatc gttaccatta ctcttatccc agctttatcc aagctcaaaa
     3841 aatcataata ttgctcaagc tatgaagcat gctgtctgat aaggatagca tgctttaatg
     3901 atatgtgaca agcaaggaaa ttgatcctta tgtgaaaaaa tgattggaag ctattacaga
     3961 aaataagtga tttttccttt tcaacatgat ataatcccga ctttatcact taaaaacaag
     4021 taaagaccag ctaacccctt gtgtcccaag ggattttgct ggtctttaaa tttattttag
     4081 tgttgtatat ggatttttag cgtaatgttt gagctcttca aacttaacga ttcccttcgc
     4141 ccattcaatt cctagcagtc tgtttaactc
//
LOCUS       DARYXS010000118         4090 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.119, whole genome shotgun sequence.
ACCESSION   DARYXS010000118 DARYXS010000000
VERSION     DARYXS010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4090
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.119"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            229..486
                     /locus_tag="TV193_001782"
     CDS             229..486
                     /locus_tag="TV193_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1513946.1"
                     /translation="MEKEQQRLYDVIKQAYDYPENRANSHLARLLLSASNQLIKNSNP
                     LTIAEQLNQALDDYLQANDLLLPKSLCGFKQSLDAYLLEKG"
     gene            523..1254
                     /locus_tag="TV193_001783"
     CDS             523..1254
                     /locus_tag="TV193_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513947.1"
                     /translation="MIEFRHVSKLYGDKEALSDVSLTIKDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYREVLVNGQLLSEHRNTIKRQIGYVPDSPDIFLNLTAYEYWQFLAKIY
                     GVSEADTKARIEELTQLFELTQEMHNTIDNFSHGMRQKVIVIGALISNPSIWILDEPL
                     TGLDPQASFDLKEMMKEHAASGNTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTVEQ
                     LKADYPDKDLETIYLELAGRQAQEA"
     gene            1259..2887
                     /locus_tag="TV193_001784"
     CDS             1259..2887
                     /locus_tag="TV193_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513948.1"
                     /translation="MNWSTIWELVKINILYSNPQSLTALKKKQEKAPKENFKAYKSMI
                     RQQALMIALFLVIYIFMFMGVDFSQYPGLLSLYIAIFFVMATVNAFTAMYAVFYESND
                     VKLYVHLPIRSEELFIAKLISSLGMGSIFLMPLLSLFVIAYWQIIGNALAIVLAFILF
                     VVLFVSSIVFALYLNAWIGRIILRSSKRRLISAVLMFASTFGALGLIVFLNMTNNQRM
                     MADQAFSDRPLIPYFRGSYDVVVAPFSSQALLNFWLPLLLVMLMLYGLVRRIMPAYYR
                     ETLYVGGKAKNAAVARKAAASDRQQSLQRLLTKHHLATLQNATLLTQTYLMPLIYVMI
                     FITPSVTSGAQFSSYITDEYFGIALLVGVLLGSICTVPTSFVGVGISLEKDNFTFIKT
                     LPISLKGFLLNKFRLLIGLQILAPLVVYALIGLFVLGFHPVIVLSFSLGFVLMGIIQG
                     QLMFRRDYRMLDLKWQDVTQLFTRGNSQWFMLGLMFGDLIVGGFLIVLAIMCATISQQ
                     PLLVSIAVSLILLSCLLFAQLWIQRSFWKNLNKM"
     gene            complement(3398..>4090)
                     /locus_tag="TV193_001785"
     CDS             complement(3398..>4090)
                     /locus_tag="TV193_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513949.1"
                     /translation="TDDSFIAVFDPKLKEIDKHIFEDSVIASDFSVDGDDIYLLGTDV
                     KIKDNYPTYLYTLSIKNGQLAMKNKELLYEQPESTYFFHDSIVKEKQLYTALSGYRNN
                     VTKERTVLGQVFHYDMQSGQKHFFDLTEIAPVNIFDLGHDTLAIEHEKNEAGKIGFSL
                     FHLNDKTSTFIDLSQFGLSIESDYLKDVKQIDENTLLILAGHTLIGYHINDHQAIFNK
                     QVSDDAFHIWVK"
BASE COUNT         1109 a          756 c          914 g         1311 t
ORIGIN      
        1 gattatcgtc tgattttgtt acctatggct aaaaataaga agcacaactg actgcccgta
       61 ttgccctaaa aaaggaacaa aagtaagcgc catcatcgtt ggtatatctg cttttgtgaa
      121 aagagacaaa tatggcgata ggatattgac aaaaagccta ataaagatta tgattgaagt
      181 gttaactagt tgtattagcg taaacgtaca aaattagagg gaggccctat ggaaaaggaa
      241 cagcagcgct tatacgatgt catcaaacag gcctacgatt acccagaaaa tcgtgctaat
      301 agccatttag ccagattatt gctgtcagct tctaaccaat taatcaaaaa cagtaatccg
      361 ctgacgattg cagagcagct aaatcaagcg cttgatgatt acttacaggc caatgatttg
      421 ttgttgccta agtccttgtg tggctttaag cagtcgcttg acgcttattt attagaaaaa
      481 ggctgaccag cacgagcgtc tggtttagga taggagagag ttatgataga atttagacat
      541 gtttcaaagc tatacggtga caaggaggcc ttgagtgatg taagcctcac gattaaggac
      601 ggtgaaatct ttggtctcat tggtcacaat ggggctggca agacgacaac aatcagtatc
      661 ctgacctcta ttatcgaagc aagctataga gaggtcttgg tcaatggtca gctgctgagt
      721 gagcatcgta acaccattaa aaggcaaatc ggctatgtgc ctgattcacc ggatattttc
      781 ttaaacctga cagcctatga atattggcag tttcttgcta agatttatgg cgtcagtgag
      841 gcggatacca aagctcggat tgaggagctg acgcagttat ttgagctgac gcaggagatg
      901 cacaacacga ttgataactt ttcacatggt atgcgtcaaa aggtcattgt gattggtgct
      961 ttgatctcca accctagtat ctggatcctt gatgagccct tgactggact ggatcctcag
     1021 gcttcatttg atctaaagga aatgatgaaa gagcatgctg cttctggtaa tacggttctt
     1081 ttttcaacgc atgtcttgtc ggttgctgag cagctgtgtg accggattgg gattttgaaa
     1141 aaggggaaat tgatttttgt tgggacagtt gagcagctaa aggctgatta tcctgataag
     1201 gatctggaga ctatttacct tgaattggca ggacgtcaag cacaggaggc atagtggtat
     1261 gaattggtca actatttggg aattagtcaa gattaatatc ctttattcca atcctcagtc
     1321 cctgacagct ttaaagaaaa agcaagaaaa ggctcccaaa gagaacttca aggcctacaa
     1381 gagtatgatc agacagcaag ccttgatgat tgctctgttt ttagtcattt acatctttat
     1441 gtttatgggt gttgatttta gccaatatcc gggactgttg tcactttata ttgctatttt
     1501 ctttgttatg gcaactgtta atgcctttac ggcaatgtat gcggtctttt atgagagtaa
     1561 tgacgttaag ctctatgttc atctgccgat aagatctgag gagcttttca ttgctaagct
     1621 gatttcctca ttaggtatgg gatccatatt tttaatgccg ctgctaagcc ttttcgtgat
     1681 tgcctactgg cagatcattg gaaatgcttt ggcgattgtg ctagcgttta tcctgtttgt
     1741 ggtgctattt gtcagctcga ttgtttttgc tctgtatctc aatgcttgga ttggcaggat
     1801 tattctgagg agtagtaagc gcaggctgat ttcagcggtt ttgatgtttg cttctacctt
     1861 tggtgctcta ggcttgattg tatttctcaa tatgactaac aatcagcgaa tgatggctga
     1921 tcaagccttt tcagatcgcc ctttgattcc ttattttagg ggcagctatg atgttgttgt
     1981 ggcaccgttt tccagtcagg ctctgcttaa tttttggctt cccttgcttt tggtcatgct
     2041 gatgctgtat ggtcttgtta gacggatcat gccggcttat tacagagaga ccctctatgt
     2101 tggtggaaaa gctaaaaatg cagcagtggc gcgcaaggcg gctgcatctg atcgtcagca
     2161 aagtctacag cgattgttga caaagcacca tcttgcaacg ctgcaaaatg cgacactatt
     2221 gacacagact tatctgatgc ctttgattta tgtgatgatc tttatcactc ctagtgtgac
     2281 aagtggtgca caattttcaa gctacattac cgatgagtac tttggtattg cgcttttggt
     2341 gggggtgctc ttgggaagta tatgtactgt gccgaccagc tttgttggtg ttgggatctc
     2401 tcttgaaaag gacaatttca cctttattaa gaccctaccc attagcttaa agggcttttt
     2461 gcttaacaaa tttcgcttgc tgatagggct gcaaatcctt gctcccttgg tggtttatgc
     2521 tcttattgga ttgtttgtat taggctttca ccccgttatt gtcctatcct tttcattagg
     2581 ctttgtcttg atgggaatca tacaagggca attgatgttt aggcgtgatt accgcatgct
     2641 ggatctgaaa tggcaggacg tcacccagct tttcaccaga ggaaatagcc aatggtttat
     2701 gcttgggctg atgtttggcg acttaattgt tggtggcttt ttgattgttt tagcgattat
     2761 gtgtgctacc attagtcagc agcctcttct tgtgagcatt gctgtgagcc ttattcttct
     2821 tagctgtttg ctctttgccc agctctggat tcaaagaagc ttttggaaaa atctgaataa
     2881 gatgtaaata gctctggggt attaattctc cagattggcc aaggtaagat gtgacgaagt
     2941 tttggttcta gctcaaatag tgagagtaat tgcagtaact atatgttaaa agctagagca
     3001 gctattgaaa aaagaaagca aaaagcttta gcaagctagc agtgccctac ggtgctagct
     3061 tgtggggcat caagatcaag ctcctaaagc tgttagtgat gttgctcgac acatagcttt
     3121 gggagcctca cgaaaaaagc taactcaact gttgcagctg ctagctttag atcaacagtc
     3181 atgtgctaaa ccattttcaa aaagagcttt tatgacgttt ggattgaagt gacattctga
     3241 taacccatca caagcatgct ggctttatca catcttaatg gcagttccaa atactactaa
     3301 tttaggctag cttcttagaa aaagctagcc taactatttt aactaaaaag tcaaggactt
     3361 gtgctttgac cttttgttgt tttcagtaac tgagtagcta ttttacccat atatgaaagg
     3421 catcatcact cacttgtttg ttaaagatag cttgatggtc attgatatgg tatccgatta
     3481 atgtatgacc agctaatatt aatagggtgt tctcgtcaat ttgtttgaca tcttttaagt
     3541 agtcactttc aatggataaa ccaaattgag ataagtcaat aaaagtagac gttttatcat
     3601 tgaggtgaaa caggctaaac ccaatttttc cagcttcatt tttctcatgc tctattgcca
     3661 gtgtatcgtg acccaaatca aaaatgttga ctggagcaat ctcagtgaga tcgaaaaaat
     3721 gtttttgacc tgactgcata tcataatgga aaacctgccc taaaacggtt ctctccttgg
     3781 taacattgtt tcgatagccg cttaaggcgg tatagagctg cttttctttg acaatgctat
     3841 catggaaaaa gtaagtggat tcaggctgtt catagagcag ctctttgttt ttcatagcta
     3901 attgcccatt tttgatagat agcgtatata agtaggttgg gtagttatcc ttgattttca
     3961 catctgttcc taagaggtaa atgtcatctc catcaactga aaaatcgcta gcaatgacag
     4021 aatcctcaaa gatatgctta tcaatttctt tgagcttagg atcaaaaaca gcaataaaac
     4081 tatcgtcggt
//
LOCUS       DARYXS010000119         4023 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.120, whole genome shotgun sequence.
ACCESSION   DARYXS010000119 DARYXS010000000
VERSION     DARYXS010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4023
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.120"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            37..1467
                     /locus_tag="TV193_001786"
     CDS             37..1467
                     /locus_tag="TV193_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1513950.1"
                     /translation="MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMES
                     RAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKR
                     HQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRRKKKKGRLRRFFRILFFLLLLLV
                     AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDART
                     DTIMVVNVGNKENKIKMVSFMRDTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGA
                     EFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVP
                     DDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQI
                     KDPTKLFTGSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDE
                     YDMYGGQALFIDFAKYQNRLSKLGLR"
     gene            1545..3176
                     /gene="rlmD"
                     /locus_tag="TV193_001787"
     CDS             1545..3176
                     /gene="rlmD"
                     /locus_tag="TV193_001787"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1513951.1"
                     /translation="MLSKNDIVQVEISDLSHDGLGIAKHEGFVFFVENALPGEIIQMR
                     VLKVNKNSGFGKVETYLTTSPMRQKKLDVTYLRTGIADLGHLLYPQQLLFKQKQVQDS
                     LYKIAGISNVEVKETIGMEYPYAYRNKAQVPVRRVNGQLETGFFRKHSHELVPISDFY
                     IQDKEIDRLIAFTRDLLRRFDIKPYDEKEQSGLIRHLVVRRGHYSGEIMLVLVTTRPK
                     IFRINQMIDSLVAEFPAITSILQNINDKPTNVIFGKAFTRLYGKETITDTILGNQYCI
                     SAQSFYQVNTTMAEKLYQTAIDFSELTADDVVIDAYSGIGTIGLSFAKEVKAVYGVEV
                     IEAAVRDAEKNAALNGITNAYYVADSAENAMANWCQEGIKPTVIIVDPPRKGLTESFI
                     KASAAMQPDKITYISCNPATMARDIKRYEELGYKLQKVQPVDLFPMTHHVETVALLSK
                     LNVDKYISVEIELDELDLTSAESKATYAKIKEYILEKFGFKVSTLYIAQIKRKCGIEL
                     RENYNKSKKDKQVIPQCTPEKEKAIMDALRHFKMI"
     gene            3196..3477
                     /locus_tag="TV193_001788"
     CDS             3196..3477
                     /locus_tag="TV193_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513952.1"
                     /translation="MRWIIKIILFPFSLLLSVLTAFLTFILGIGTTILYFLMLMCIVA
                     AIGSFMQKDISLGIEALVLGFLLSPYGIPMVGAAVIAFFKGINEAIKSI"
     gene            3492..>4023
                     /locus_tag="TV193_001789"
     CDS             3492..>4023
                     /locus_tag="TV193_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL1513953.1"
                     /translation="MVTKGDREKLSSFSLQIFKEGGEAMDFDYFYNREAERFNFLKVP
                     EILVDGEEFKGLSAEAIILYSMLLKRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNIS
                     KPTAIKTLDELDSKKGIGLIERVRLGLGKPNIIYVKDFMSIFQVKEDDLQKLKNFTSE
                     VKDFNLRSKENELQEVK"
BASE COUNT         1288 a          694 c          893 g         1148 t
ORIGIN      
        1 aagaaattgt attagaatac taagagttgg aagagcatga cgagatacca aaagggtggt
       61 ctaagccacc acgaagaatt acgatatttt tatttattaa gaaatttaaa ttatttgact
      121 gagactgaac gcagagaatt taccttttta aagtcaaaga tggagtcaag ggctatgcct
      181 tctcgttctc agcgctcctt gactcattat actaggggtg ggcgtgacga ttatgctcaa
      241 gcttcacagg ataatgctga tgcttatgat atgagtgatg agcagcaggc tgggcctaat
      301 ggcctgcctc tttatccaag atcagaaaga cgtagcaaaa ggcatcagca aaagccaata
      361 ctagcccctc agcaggactt ctatgatgac ccagatcagg cgatctatga ggagcttgcg
      421 cctgaggcta tgcctaaaaa gggtagaagg aaaaaaaaga agggacgtct gagacgtttt
      481 ttcagaatac tctttttctt gttgctgctg cttgttgcag ggatagcttt catgtttttc
      541 aagggaatga tggacgtgtc tactaacaag gccaattata agccagcagt ttcgcaggtc
      601 tttcatggtc aggatactag cgatggcact aatattttaa ttctaggctc agaccagagg
      661 attacgcaag gctcaacaga tgctcgaaca gatacaatca tggtggttaa tgttggcaat
      721 aaggagaata aaatcaaaat ggtctccttc atgagggata ccttggttaa tattcctggc
      781 tatagctata ataatcagga ttcctatgat ttaaaattga acgcctcctt taatttagga
      841 gagcaggaaa atcatcaagg agcagaattt gtgcgtcaga cactcaagca taattttgat
      901 attgacatta aatattatgt catggttgac tttgaaacct ttgctgaggc tattgacaca
      961 ctgtttccag atggtgttac cattgatgcc aaatttgcta ctgtaaatgg cgaagcagtc
     1021 gctgctgttg atgtaccaga tgatttacga atgaaagacg gagtggttcc caaccaaacc
     1081 ataacggttg gtgagcaaaa aatggatggt cgtaccctgc tcaactatgc tcgcttccga
     1141 aaggacgatg agggtgattt tggtcggacc gtacgtcagc agcaggtgat ggctgctatc
     1201 atgtctcaaa tcaaggatcc aaccaagctc tttacgggct cagcagctat tggtaagatt
     1261 tatgccctaa cctcaaccaa tgtctccttc ccatttgtcc ttaaaaatgg agtgtccgtc
     1321 ttgactaatg gcaaaaacgg tgtggagcat gtgacgattc ctgaaaatgg ggattggatt
     1381 gatgaatatg acatgtatgg tggtcaggct ctctttattg attttgctaa gtatcaaaat
     1441 cgattatcta agctgggatt acgctaagat atgctataat gaagggtaac gatggttgct
     1501 cttctttttt gagtgattag tgtagtaaaa gaaaaggaaa gtaaatgtta agtaaaaacg
     1561 atattgttca ggtggaaatt tctgatttaa gccatgatgg cttaggaatc gctaagcatg
     1621 aaggctttgt tttctttgtt gaaaatgctc ttccaggtga gatcattcag atgcgtgtcc
     1681 taaaggtcaa taaaaacagt ggctttggca aggtagagac ctatctaaca acctcaccga
     1741 tgcgtcaaaa aaagctggat gtgacctatc tgcgtacagg tattgctgat ttggggcact
     1801 tgctttatcc gcagcagctg ctctttaagc aaaagcaggt tcaggatagt ctctataaga
     1861 ttgcagggat tagcaatgtt gaggtcaaag aaacaattgg tatggaatat ccttatgctt
     1921 atcgaaataa agcccaggtt cctgttcgtc gtgtcaatgg tcagctagag actggttttt
     1981 tccgtaagca ttctcatgag ctagtgccga tttctgattt ttacattcaa gataaggaaa
     2041 ttgatcgctt gattgccttt acacgcgacc ttttgcgccg ttttgacatc aagccctatg
     2101 acgaaaagga gcagtcaggc ctgattcgtc atcttgtggt tcgtcgtggg cattattcag
     2161 gagaaatcat gctggtttta gtgacaacac gacctaaaat ctttcgtatc aaccagatga
     2221 ttgatagcct tgtcgcagaa tttccagcga ttacttctat cctgcaaaat atcaatgaca
     2281 agcctactaa tgttatcttt ggtaaggcgt ttacaaggct ttatggaaaa gagacaatca
     2341 cagatacgat cttgggcaat caatactgta tttctgctca gtccttctat caggtcaata
     2401 caacaatggc tgaaaagctc tatcaaacag ctattgattt ttctgaattg accgctgacg
     2461 atgtggtgat tgatgcctat tcaggcattg gaaccatcgg gctatccttt gctaaagaag
     2521 tcaaagcagt atacggtgtc gaagtgatcg aagcagcagt gcgtgatgcc gagaaaaatg
     2581 cagcgctaaa cggtattacc aatgcctact atgtcgctga cagcgctgaa aatgcgatgg
     2641 caaactggtg tcaggagggc ataaagccaa cagttatcat tgtagacccc ccacgaaagg
     2701 gactaactga gagctttatc aaggccagtg cagcgatgca gcctgacaaa ataacctata
     2761 tatcctgcaa ccccgccacc atggcgcgtg acatcaagcg ctacgaggaa ctcggctata
     2821 aactccagaa agtccagcca gtagacttgt ttccaatgac acatcatgtc gagacggtag
     2881 cattattgtc caaacttaat gtcgataagt atataagtgt tgaaatagag cttgatgaac
     2941 ttgatttgac aagtgcagaa agcaaggcta cctatgctaa aattaaagag tatatattag
     3001 aaaaatttgg ttttaaagtt tcaacactat atatagcaca gataaaaaga aaatgtggaa
     3061 tagaacttag agagaattac aataaatcaa aaaaagataa gcaagttatt ccgcagtgta
     3121 cacctgagaa agaaaaagct attatggatg cgttaaggca ctttaaaatg atttaagaga
     3181 aaggagaggt attatatgag gtggataata aaaataatat tgtttccatt cagcttgcta
     3241 cttagtgtcc ttactgcctt tctgacattt atacttggca taggaacaac tattctgtat
     3301 ttcttaatgc tgatgtgtat agttgctgca ataggatcat ttatgcaaaa agatatatca
     3361 cttggcattg aggcattagt attaggattt ttgttaagtc cttatggaat accgatggtt
     3421 ggagcagcag ttatagcatt ctttaaagga atcaatgaag caataaaatc aatctaaaaa
     3481 atttcataaa aatggttacc aaaggcgata gagaaaaact atcgtctttt tctttgcaaa
     3541 tttttaagga gggaggtgaa gcgatggact ttgactattt ttataacaga gaagcggaaa
     3601 gatttaattt cttaaaagta ccggagatat tggttgatgg agaagaattt aaaggattat
     3661 ccgctgaagc aattatcctt tattcaatgc ttcttaaacg gacaggaatg tcctttaaga
     3721 ataactggat tgataaggaa ggcagggtat ttatctattt cacagtcgaa gaaattatga
     3781 aaagaagaaa tatctcaaag ccgactgcca taaaaacatt agatgaatta gatagtaaaa
     3841 aaggaattgg actgattgaa cgggtacggc ttggacttgg aaagccgaat atcatttatg
     3901 tcaaagattt tatgagcata tttcaggtaa aagaagatga cttacagaag ttaaaaaatt
     3961 ttacttcaga agtaaaagat tttaacctca gaagtaaaga aaatgaactt caagaggtta
     4021 aga
//
LOCUS       DARYXS010000120         3801 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.121, whole genome shotgun sequence.
ACCESSION   DARYXS010000120 DARYXS010000000
VERSION     DARYXS010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3801
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.121"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..250
                     /locus_tag="TV193_001790"
     CDS             <1..250
                     /locus_tag="TV193_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513954.1"
                     /translation="TGKNRQFEYGEGGQLMISLPNPKYPDRSFLDRVTLESLLTDTEK
                     IEAVDYAFGRYEHRLEIALAILKDYLDSDEAKVLLKNE"
     gene            243..656
                     /locus_tag="TV193_001791"
     CDS             243..656
                     /locus_tag="TV193_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513955.1"
                     /translation="MSEQYLSIKESLGYKNVKQALWTIFSANLDEISIHEGEDENFNF
                     VFTYKNCEMMMGIYDTGKNIQFQAGEGGLFSVSLPNPKYPEQSFQKIVSLSYLISDKN
                     VSENIRWCLGLDLKSVEYVMRVLKDYLDQKCEEEQ"
     gene            919..1311
                     /locus_tag="TV193_001792"
     CDS             919..1311
                     /locus_tag="TV193_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623140.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1513956.1"
                     /translation="MTPAFLKTGDLLDRYGESGGTFTSPIVDRKVIPFNKRGLPYPED
                     YQNYHQYKVLKDINMENVEKGYHNLSDSRKKELNLLMNRFDFSLVDIATPQKGMIDLV
                     FGSGGGIQIKLGTSVSWYEKLGLIKEIK"
     gene            1312..1635
                     /locus_tag="TV193_001793"
     CDS             1312..1635
                     /locus_tag="TV193_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513957.1"
                     /translation="MKNLDHQKAELLEAVHQLGYDSLRYSIFSKERPGEWETVIEYDN
                     SQGLYVVYATMDRASYNKKLTFETFQEAKEKFLEKLRLDIQINRYYVEEGMPVNYDSP
                     LWSKN"
     gene            1948..2418
                     /locus_tag="TV193_001794"
     CDS             1948..2418
                     /locus_tag="TV193_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1513958.1"
                     /translation="MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALPPEKI
                     RAWMYRVAVRKYIDRYRRDKAYLDILQRDFFHQERVVEFDHPNYEPLYTAVNELPEKY
                     RWVLSFYYFQDLSVKEMASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFN"
     gene            2402..3495
                     /locus_tag="TV193_001795"
                     /pseudo
     CDS             2402..3495
                     /locus_tag="TV193_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623137.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
BASE COUNT         1262 a          624 c          800 g         1115 t
ORIGIN      
        1 aactggtaag aatagacaat ttgaatatgg agaaggagga caattgatga tttcacttcc
       61 taatccaaag tatcctgata gatcctttct tgatagggta accttagaaa gtcttttaac
      121 agacaccgaa aaaatagaag cagttgacta tgcttttgga agatacgagc atcgtctcga
      181 aatagcgttg gccattctaa aagattattt agattcagac gaagcaaagg ttttattgaa
      241 aaatgagtga gcaatattta tcaataaaag aaagcttagg ttataagaac gttaaacagg
      301 ctttatggac tattttttca gccaaccttg atgaaatttc tatacatgaa ggagaagatg
      361 agaattttaa ctttgtcttt acatataaaa attgtgaaat gatgatggga atttatgata
      421 ctggtaagaa tattcaattc caagctggag aaggtggttt attcagtgta agtttaccta
      481 atcctaaata tccggagcag tcatttcaaa aaattgtatc actttcttat ttaatttctg
      541 ataaaaatgt aagtgaaaat ataagatggt gcttaggact ggatctgaaa tctgttgaat
      601 atgttatgcg tgttttgaag gattatctgg atcaaaaatg tgaagaggaa caataattct
      661 aatcacttct ggagggcata tagatgagtg aagaacagta tttaccaata ccttcgaaga
      721 gaataccagt taaagggaag gtattttgca gaaagaatca ccatgccaga tggaaaatat
      781 gcttatctgt ccaatgacat tgataaagct accggaacac caattcctgt ccgatataga
      841 aattacctta aggctgatgg ttctattaat tggccaaact ataatggctt tagtcttgat
      901 gtaaagggaa ggcctatcat gactccagct ttcctaaaaa caggtgattt acttgataga
      961 tatggagaat ctggaggaac attcacaagt ccaatcgttg accgtaaggt tataccattt
     1021 aacaagcgag gcttaccata cccagaggac tatcaaaatt atcatcaata taaggttctt
     1081 aaggatatta atatggaaaa tgttgaaaag ggttaccata atttatctga tagtagaaaa
     1141 aaagagttaa atctattaat gaatagattt gatttttcac tggtagacat agcaactcca
     1201 caaaaaggaa tgattgatct tgtctttggc tctggtggag gtatccaaat aaagttagga
     1261 acttctgtaa gttggtatga aaaattgggt ttaattaagg agataaagta gatgaaaaat
     1321 ttagatcatc aaaaggcaga actattagaa gcagtccatc aattaggtta tgatagtcta
     1381 aggtattcca ttttttctaa agagagacca ggagaatggg aaactgtcat tgaatatgat
     1441 aatagtcaag gcttatatgt tgtgtatgca actatggata gagctagtta taataagaaa
     1501 ttaacatttg aaacatttca agaggctaaa gaaaaatttc ttgaaaaact tcggttagat
     1561 atccaaatca acaggtacta tgtggaagag ggcatgcctg taaattacga ttctcctttg
     1621 tggtcaaaaa attaatacaa gtaaaggaga atatacatgg catgtagtca attagagtgg
     1681 gaagataaat gaaataatgg tcctaggaaa tgtcccgact ggaaactatc ttatgaactc
     1741 ttttatggaa aagtgttgca cttaatttga attttgtcat ataaaaaagc cctataatct
     1801 ccatggtgga cttacccact acagaaatga tagagctaaa aatctccatt tggggatttt
     1861 tttgtaacca aatgaagcag tcgttcgtta tataggtgaa gaagggaggg gagaattatc
     1921 aggctagatg cttatgaaag agagctagtg gcttattcta aggaaattat tgcctaccta
     1981 gtgagatcag gtgttgctaa ggagctagcg cgtgatatta gtcaagacgt tttgttaaaa
     2041 atgcttgaga gtgaccttgc tctgcctcct gaaaaaatac gtgcctggat gtatcgggtt
     2101 gctgttagaa aatacattga ccgatatagg cgggataagg cttacttgga tattctccaa
     2161 agggattttt ttcatcaaga aagggttgtt gaatttgacc accccaatta tgagccgctt
     2221 tatacagcag tcaatgaatt gccagaaaaa taccgctggg tcttgtcgtt ttattacttt
     2281 caggacctat cagtcaagga aatggcgtct ctgctccatt ggtcagttag cagcgtcaag
     2341 gtcaacttga tgcggggaag acgatgcctt aaagaaaaac taaagaaagc aggttatacc
     2401 tatgacgatt tcaactgatt ttgaagccat tgctaagcgc cataaaagga ggctgaccct
     2461 taaatatgta gtgctgagtg ctggcttagc cttagtagct cttgtactgg gctatatggg
     2521 attaaatcga ttgacaagca tgaacggtca gtatttaatg gcttattaca acaatcgtat
     2581 acaaattgct tatcccaata ttgatgttaa tagcttcttt tacaatgcca attcgcagtt
     2641 tactggtgag cttcattctg agcggaccaa ggatattgct gggatttcgg taccgtttga
     2701 gccctataga gctccttatt ccttgccttt acccagagag agatggacta taccaatgaa
     2761 taccttgttt caggtgatga tggacggtca acctacacaa gaggtacaca ttataaaatg
     2821 cctcgcttct tcaacactaa ggccaagatc acagaaagca actatgacaa gccaacgcag
     2881 gacctagact ttattgctga catgtcagga caggcgattg aggtagccat tacctttgat
     2941 aagccttatt tattatcgga catagtcaag ctggttccag accagctaaa gctgaattgg
     3001 atctggattg gcacagaaag cagctatgac acctcagggc ttttccctgc taatttatat
     3061 ggctttaagc caaactggaa ggctaatatg acgtacaagg agcaaaagca gttagataaa
     3121 aaaataaacg atatcctaaa aaaggacagc gaggctgatt tgtctaagct taatgctgct
     3181 tacgataagc cagtcagtcc aacggtggct ctgcaaaatt cctatgatac cttcaggcac
     3241 tatctacaag aggcagctga caatcattgg attaatagta cctatggcgg cgctaatgga
     3301 tctcatttaa gtgagcagga ggatgtggcc ttatttctaa aaaacaatcg caatgtcaaa
     3361 acagctaagt ttgctggcat tattttaacc ggcaaggctg agcagtttgc ctccttaaaa
     3421 acagctgatt ggatttatgc ctcaaatatt ggtcagtctg ttgccattca gccctatcat
     3481 cagctaacca agtaaataaa aagcttgtgc tgctaatcaa gcgcatcagg caaaggataa
     3541 aaagcctaaa agagattaga ttaagtaaat cgatgcttaa aaaagctcca gcttaggtca
     3601 aaagacgtca aaaggctctt ggaggtcagt gtttgatcac tgcttctggg gctttttgct
     3661 ttgctgcaat caaaaaagct tgaagcagct ctctcaattg agcatgtcct tcaagctgag
     3721 actcttatat tttatagtat ttgtaagtat agttttagct agccttcttt taagcccaag
     3781 ggcttagctt actgtttagt a
//
LOCUS       DARYXS010000121         3760 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.122, whole genome shotgun sequence.
ACCESSION   DARYXS010000121 DARYXS010000000
VERSION     DARYXS010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3760
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.122"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..1790
                     /locus_tag="TV193_001796"
     CDS             <1..1790
                     /locus_tag="TV193_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1513959.1"
                     /translation="AMGNRQMKLKKYFLRFLLLLFAAIYIYFSSFAYQHSYLGISADY
                     VNHSWVVSNIHNGGEASSSGLAVGDKILEIDHKSSQDNPLLNKLLIVEQATSMTVLHQ
                     GIQRQIVFQKTHGSKKIFLMFSLLSIILFALSYGYSRRHEISRTSQRYYIFTFLTSLL
                     LVSIIPSSMGNVVARLILVIYITLFPFFIDMFWRAGTLQQESVKFSKFSKLIITYSAA
                     TLCLLLYSKWFSVPLVITIYLVRGIFYVSFTFLVALFLITLVKDIKNNAFPRLNIVLL
                     VILCLLPLFIGYVFPLPYDIPFMYTIPLLLLPILAIINNLIINRLTTFRFHLPVPILY
                     VFIAMLGTVMIICLYLISDFMPKWLMISYSFLLTLCSIPIVKDLIFLNIRTGYQLSNK
                     SIFLAVEAEREDISIYLHDTIIQDIIYYKKRLENMDAVSKKAASDILDDVIFELRELC
                     SNIYPLMIQELGLKNAILDIISKFQKKESVIINDNIQVEQLDFGQPINNFILRSIREL
                     INNSILHGNAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEKLALLG
                     GQLLVDKHPTTIVMLIPRKQVNYDKNSNH"
     gene            1768..2367
                     /locus_tag="TV193_001797"
     CDS             1768..2367
                     /locus_tag="TV193_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1513960.1"
                     /translation="MIKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLK
                     YKSVDVLIIDLMLKDIHGFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAF
                     LPKECSYDELISTVYNVAKGNQVIPDDLLQREESHLLTESEIEILKLISDEYSNEKIS
                     KKLYISRRTVDTHVSNICAKLNVTSRVGAVREAIRLKLI"
     gene            2475..3401
                     /locus_tag="TV193_001798"
     CDS             2475..3401
                     /locus_tag="TV193_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="avirulence protein"
                     /protein_id="HEL1513961.1"
                     /translation="MVDVDTLLGDHKTRYFGDGHKRTSYSINHDQNNQAYGTITQSGV
                     WSNKSDKVIQPHLSTLDGIVLASLAAERYLKEQYEACEDFYLSQFSVKSGRKPIEDLN
                     RVPIVVQKSSFNGDKASFSVSVLDMTVNLVFKRIDTYTAKDNKPAAEAKDYLSNHLKD
                     IHHHIYDVNFLDALDIADKCSIFCKANKAIRHVSNYKGISSQLSSSYSLLELLIIFSQ
                     MAEMLAYYADDIDRRYSETLWMKNVSAELVEPIPDGELALLGKITKNKLLDMKGKDWK
                     LFEMSGTDTQNRVRISSKIAHQLPSSEMLNNA"
     gene            3394..>3760
                     /locus_tag="TV193_001799"
     CDS             3394..>3760
                     /locus_tag="TV193_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1513962.1"
                     /translation="MLNKEIRLVISGTYSTGKTTTATALSIATGIPLINALSAREILT
                     DLYPGRRFQDMNATELMALGLKRFEERVREEAILYLQHTNFISDGSVLNEWIYGTVRM
                     KVGLNPGSGFIHRAAKAILG"
BASE COUNT         1158 a          706 c          739 g         1157 t
ORIGIN      
        1 gagcaatggg taaccgtcaa atgaagctga aaaaatactt cctcaggttt ttattgttat
       61 tatttgctgc aatctacatt tatttttcct cttttgccta tcagcattcc taccttggga
      121 taagtgctga ttatgttaat catagctggg ttgtcagcaa tatccataat ggcggggagg
      181 ctagctcctc aggactagct gttggggata agattttaga gatagaccat aaaagcagcc
      241 aggacaatcc tttgttaaat aagctgttaa ttgttgagca agcaacctca atgactgttt
      301 tgcaccaagg catacaaaga cagattgtat ttcaaaaaac acatgggtct aaaaagatat
      361 ttttaatgtt tagcctgtta tccattatct tatttgcctt atcctatggc tattctagaa
      421 ggcatgagat cagtcggacc agtcagaggt attacatctt taccttttta acatcgttat
      481 tactggtttc gattattcca tcaagcatgg gaaatgttgt tgcccgcttg attttagtga
      541 tttacatcac tttgtttccc ttttttattg atatgttttg gagagcaggt acattgcaac
      601 aggaatctgt taaattttca aaattttcaa aactgatcat cacctattct gctgcaaccc
      661 tctgcttatt gctatattct aagtggtttt cggtcccact cgtcattacc atttatttgg
      721 ttcgaggaat tttctatgtt agctttacct ttttagtggc tttattttta atcaccttgg
      781 ttaaagatat caaaaacaat gcttttccaa gactcaatat tgtcctgttg gttatcctgt
      841 gcttgctgcc attgtttatc ggctatgtgt ttcctttgcc ttacgatatc ccttttatgt
      901 acacgatacc cctattgctg ctgccgattt tggcgatcat taataaccta atcattaaca
      961 ggctcacgac ctttcgcttt catttgccag ttccaatcct ctatgtgttc attgctatgc
     1021 taggcactgt gatgatcatt tgcttgtatc tcatatcaga ctttatgcct aagtggttaa
     1081 tgattagtta tagcttttta ctaaccctgt gctcaatacc aatcgtaaaa gacctgattt
     1141 ttttaaatat cagaacaggc taccagctga gcaacaagtc tattttccta gcagttgagg
     1201 ctgaaagaga ggatatttcg atctacctgc atgatacgat catacaagac attatttatt
     1261 acaaaaaaag gctggaaaat atggacgccg tctcaaaaaa ggctgcttca gatattcttg
     1321 atgatgtaat ctttgaatta agagagctgt gctcaaatat ttatcccttg atgattcaag
     1381 agctaggctt aaagaatgct attttagaca ttatctctaa atttcaaaaa aaagaatcgg
     1441 tgattatcaa cgacaatatc caagtggaac agcttgattt tgggcagccc attaataatt
     1501 ttatcctcag atcaatacga gagctgatta ataatagcat tcttcatggt aatgctaagg
     1561 aaatagatat acacatctac aatgctgagc aatacgttgt gatcaagatt gttgatggcg
     1621 gacattttaa gactgctcgt cagacagaag cgcctcactt tggcttaact gttatcgctg
     1681 aaaagttagc attgctgggt ggtcaattgc ttgttgacaa acaccctacg actattgtca
     1741 tgctcattcc tagaaagcag gtgaattatg ataaaaatag caatcattga cgaccacgaa
     1801 ttggtcttac aaggcctata tgatcggtta aaaaaggaaa cacattttga ggttgtcggc
     1861 gcttttacca gctaccaaga tttgttattt tgcttgaaat ataagtctgt tgacgttttg
     1921 attattgatc tcatgctaaa ggatattcat ggctttgact taattgcaca aatccagcag
     1981 aaatgtcaga ccgtgccaaa aatgatttta atttcaggat tttatgagcc cttgctgcac
     2041 aaaagagcct tggatctagg cataaaggcc tttcttccaa aggaatgctc ctacgacgaa
     2101 ttaattagca ctgtctacaa tgttgcaaag ggaaatcaag tgattccaga tgacttgctg
     2161 cagagggaag aaagtcatct gctaaccgag tcagaaattg agatattgaa attaatctca
     2221 gatgaatact cgaacgaaaa aatctccaaa aagctctata tcagcagaag gactgttgat
     2281 acccatgttt caaatatatg tgctaagctc aatgtaacaa gccgagttgg agcggtgcgg
     2341 gaggctatca ggctgaagct gatctaacaa gtcaaccaaa aaaggcagac agatattcgt
     2401 aaattacgga tgtctgtttt ttgatagtgt tttatcataa gccttggtta taaataagaa
     2461 aaggagagaa actaatggtt gatgtcgata cattacttgg tgaccacaaa acaaggtatt
     2521 ttggtgatgg tcacaaaaga acaagctaca gtataaatca tgaccaaaat aaccaagctt
     2581 acggaacaat tacccaatcg ggtgtgtggt caaataaatc tgataaggtg attcagccac
     2641 acctaagcac cttagatggc attgttctag ccagtctagc agctgaaaga tatctaaaag
     2701 agcaatatga agcatgtgaa gatttttatt tatctcagtt ttcggtcaaa tcaggcagga
     2761 agcctattga agatttaaac agggttccaa ttgttgtcca aaaaagctct ttcaatgggg
     2821 ataaggcaag cttttcggtg tcagtgctgg atatgactgt taatctagta tttaaacgca
     2881 ttgacaccta tacagcaaaa gacaacaaac cagctgcaga ggcaaaggat tacttgtcaa
     2941 atcatctaaa ggacattcac catcatatct acgatgttaa ctttttagac gcattagata
     3001 tagcagataa gtgctctatt ttttgtaagg ctaataaggc aatccgccac gtcagcaatt
     3061 ataagggcat atcctctcag ctatcaagca gctattcctt attagagctc ttgattattt
     3121 tctcacagat ggctgaaatg ttggcatatt atgctgatga tattgataga agatacagtg
     3181 aaaccttgtg gatgaaaaat gtatcagccg agctcgttga accgatacct gatggtgagc
     3241 tggccctttt aggtaaaatt accaaaaaca aattacttga tatgaagggc aaggactgga
     3301 agctgtttga aatgtcaggt actgacacac aaaatcgagt gagaatttca agtaaaatag
     3361 cccatcaatt acctagttcg gagatgctta acaatgctta ataaagaaat tagacttgtc
     3421 atatcaggca cctattctac tggtaagaca acaacagcaa cggctctgtc tattgcgaca
     3481 ggcatacctt tgattaatgc actttcagcc agagagatcc tgaccgacct gtatccaggc
     3541 agacgctttc aggacatgaa tgccactgag ctaatggctc taggattaaa aagatttgag
     3601 gagcgggtgc gcgaggaagc cattttatac ctccagcata ccaactttat ctcagatggc
     3661 tccgtgctaa atgaatggat ctatggaaca gtacgaatga aggtaggctt aaatccgggc
     3721 tctggcttca ttcatcgagc tgcaaaggcc atccttggac
//
LOCUS       DARYXS010000122         3459 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.123, whole genome shotgun sequence.
ACCESSION   DARYXS010000122 DARYXS010000000
VERSION     DARYXS010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3459
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.123"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            158..490
                     /locus_tag="TV193_001800"
     CDS             158..490
                     /locus_tag="TV193_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEL1513963.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI
                     LTSIDNRD"
     gene            505..2076
                     /gene="ffh"
                     /locus_tag="TV193_001801"
     CDS             505..2076
                     /gene="ffh"
                     /locus_tag="TV193_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEL1513964.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV
                     ALPVVKTFIKRIRERAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT
                     VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMGELREVKALAKPNEI
                     LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAAKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEEREQPE
                     LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP
                     KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM
                     KRQANKIKKAKKKRK"
     gene            complement(2229..3452)
                     /locus_tag="TV193_001802"
     CDS             complement(2229..3452)
                     /locus_tag="TV193_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1513965.1"
                     /translation="MINVAFNSKIGISAQEHDQFVKQHQQVNLLQSSSWAAVKNQWQN
                     ERIGIFQGDNQVASMSLLIKPLPFGMTMIYIPRGPVMDYTNADLVAFTIKTLKAYGKK
                     KRALLIKFDPMILLKQHQLGEKAPDNSKALTIIKHLKRFGAHWTGPTTKLSDTIQPRF
                     QANCYTNADIEASFPKHTKRLMKDARQRGVIAYRGNQSDLHTFADLISLTEKRKGVAL
                     RNEAYFRQLMTTYGDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARL
                     TDQKQSLQRYLSEFKDFLDKYPDEVVIAGILSISYGNTMEMLYAGMNDDFKKFYPQYL
                     LYPKVFMDAYHDDIAWANMGGIDGSFKDGLTAFKSNFSPTIEEFIGEFNLAISPFYHL
                     ANLLYKIRKQLKHRH"
BASE COUNT         1078 a          661 c          707 g         1013 t
ORIGIN      
        1 ttttcaacac ttgtcaagta tatcaatatt tcaagaacag ttattaaaac aagctactat
       61 tatcctcatt tttgctctaa gaaagcttcc tgataaaagg ctgatcgcta tcatttacca
      121 ctgttaaaaa tgctcatgat gtgataaaat gaagattatg gaaattgaaa aaacaaaccg
      181 aatgaatgct ctttttgaat tttatgctgc cttattgact gataaacaga tgaactatat
      241 cgagctctat tacgctgatg attatagtct ggctgaaatt gctgaagaat tcggtgtcag
      301 ccgccaagca gtttatgata atattaagcg cactgaaaaa attctggaag cctatgaaat
      361 gaagcttcat atgtattcag attatattgt acgtagtgaa atatttgatg atattcttgc
      421 aaaatatccc agtgaccact atttacgtga caaaatttcc attttaacta gtattgacaa
      481 cagagattaa gaggagttat agctatggca tttgaaagcc taacccaacg tttacaggac
      541 gtttttaagc acattcgtgg taaaaaaacc ttatctgaag ccgatgttca ggaagtgacc
      601 aaggagattc gtctagcctt attagaggca gatgttgcac ttccagttgt taagaccttt
      661 atcaagcgta tacgtgagcg agctgttggc cacgaaatta ttgataccct tgatccaacg
      721 caacaaatac ttaaaattgt taatgaggaa ttaactggta tcttaggatc agaaaccgcg
      781 gagcttgata aatcacctaa aatccctact gtcatcatga tggtgggctt gcagggagct
      841 ggtaaaacga cctttgcagg aaaattagcc aataagctca tcaaggaaga aaatgctcgt
      901 ccattgatga ttgcagcaga catctatcgt ccggctgcta ttgaccagtt gaaaaccttg
      961 ggacagcaaa taaatgttcc tgtttttgat atggggacaa atcattcagc agttgatatt
     1021 gttgccaatg gtttggcaca ggcaaaagag aaccgtcatg actatgtttt gattgatacg
     1081 gcaggacggt tacaaattga tgagaaacta atgggcgagc ttcgtgaggt taaagcacta
     1141 gctaaaccaa acgaaatcct tcttgttgtt gacagcatga tcggacaaga agctgccaac
     1201 gttgcctatg aatttaacaa tcagctcgat atcactggag tagtgttaac aaagattgac
     1261 ggtgatactc gtggtggtgc ggccctttct atacgtgaaa taactggtaa gccaatcaaa
     1321 tttaccggaa ctggtgaaaa aatcaccgat attgaaacct tccatccaga ccgtatgtca
     1381 agtcgtatct tgggaatggg agaccttctt accttgatcg aaaaagcaag tcaggaatat
     1441 gatgagaaaa aatcattaga gcttgccgca aaaatgcgtg agaatacctt tgattttaat
     1501 gactttatcg agcaattaga ccaagtgcaa aacatggggc caatggaaga tctgttaaaa
     1561 atgattccag gtatggcaac taatcctgct ctagccaata ttaaggttga cgacaagcaa
     1621 attgctcgca agcgtgctat cgtttcttct atgacacctg aggagcgtga gcagccagag
     1681 cttttaacac caagtcgccg ccgtcgcatt gcagctggat caggtaatag tttcgttgaa
     1741 gtcaacaaat ttattaaaga ttttaaccaa gccaaagcca tgatgcaggg tgtcatgtca
     1801 ggtgatatga ctaaaatgat gaaacaaatg ggaatcaacc ctaataacct ccctaaaaac
     1861 atgccaaata tgccaggagg catgcctgat atgtctgccc ttgaaggaat gatggggcaa
     1921 ggtggtttac ctgacatgtc tgcattgggt ggtgatatgg atatgagcca gctctttgga
     1981 ggtggtctaa agggtaagat tggtcaattt gccatgaagc aggccatgaa gcgtcaagct
     2041 aataagatta aaaaggccaa gaaaaaacga aaatagacta aaagaatggt tgccttgtat
     2101 tctgcctcta atcgttagat gctattctaa tttggagtgc aggtcagtag cgaccatctt
     2161 ttttataaat acaatcacta gatctttggt tctaaccatt aaacatgata tcatttcact
     2221 attagctgtt agtgcctgtg ctttaattgc tttctgatct tatatagcaa attagccaag
     2281 tgataaaaag gactgattgc taggttgaat tctccaataa actcttcgat agttggactg
     2341 aaattggact taaatgctgt caatccgtcc ttgaaggagc catcaatgcc gcccatattc
     2401 gcccaagcta tatcatcatg ataggcatcc ataaagactt taggataaag caggtactga
     2461 ggataaaact ttttaaagtc atcattcatg ccagcataga gcatttccat cgtgttgcca
     2521 tatgaaatcg ataaaatgcc cgcaatgaca acctcatctg gatatttatc caagaagtcc
     2581 ttgaattctg atagataacg ctgaagcgat tgcttttgat ctgttagtct agccagtcgc
     2641 tttttttgat gcgcttgcgt ttgagcaagc tcttgttcaa cagctttcag ctgaagctcg
     2701 taattcttga gtttttctgg aagattaacc tttgctaaat gcaaataagc attgtcgcca
     2761 taagtcgtca tcagctgtct aaaataagct tcgtttctta gagcaactcc ttttctcttt
     2821 tcagttaaag agataaggtc agcaaatgta tggagatcag actgattacc tcgataagct
     2881 atcacgccac gttgcctagc atccttcatc aatcgcttgg tatgcttagg aaaggacgct
     2941 tcaatatcag cattagtgta acaatttgct tgaaaacgcg gctgaatagt atcagatagc
     3001 ttggttgttg ggcctgtcca atgggcacca aatcgcttta aatgcttaat aatggtcaga
     3061 gccttggaat tatcaggtgc tttctcacca agctgatgct gctttagcag aatcatagga
     3121 tcaaatttaa tcaaaagagc tctttttttc ttaccatatg ccttcaaggt tttaatcgta
     3181 aatgccacta gatcagcatt ggtatagtcc atcactggac ctcttggaat ataaatcatc
     3241 gtcataccaa acggcaaagg cttaatcagc aaggacatag aagccacctg attatctccc
     3301 tgaaaaatac cgatgcgttc attttgccac tgatttttaa cagctgccca tgagctgctc
     3361 tgcaagaggt taacctgctg gtgctgtttg acaaattggt catgctcttg agctgaaata
     3421 ccgatttttg aattaaaagc tacatttatc atcatattt
//
LOCUS       DARYXS010000123         3426 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.124, whole genome shotgun sequence.
ACCESSION   DARYXS010000123 DARYXS010000000
VERSION     DARYXS010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3426
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.124"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..1435)
                     /locus_tag="TV193_001803"
     CDS             complement(<1..1435)
                     /locus_tag="TV193_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1513966.1"
                     /translation="MKFTIVRNYDKLSRTILRLESDKMTIFRKKRQAINKTEMNRHLK
                     MLDLIFLGLGSMVGTGIFTITGIGAANYAGPALTISIILSAIAISILALFYAEFASRI
                     PANGGAYSYVYATLGEFPAWIVGWYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPN
                     ALNGTFDPQKGTYVDLLPVLVMLLVTAIVLMNSKAALRFNSFLVLLKFSALALFVIVG
                     LFFIDVANWSHFAPYGFGQIYGGKSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTI
                     PRGIVLSLTIVTILYVIVTMVLTGIVHYTKLDVPDAVAFALRSIGLYWAADYVSIVAI
                     LTLITVCISMTYALARTVYSISRDGLLPRALCQITEKTRIPRNATLVVGALSMICAGI
                     FPLASLAEFVNICTLAYLVIMSFAIIKLRKNAGEPQRGEFKTPFVPLLPILAIIICVT
                     FMSQYMVFTWIAFGISTILGIVVYACYG"
     gene            complement(1525..>3426)
                     /gene="ftsH"
                     /locus_tag="TV193_001804"
     CDS             complement(1525..>3426)
                     /gene="ftsH"
                     /locus_tag="TV193_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEL1513967.1"
                     /translation="VAGFQYYLRGTSTQSQQISYSKLIKHLKAGDIKSLSYQPSGSIV
                     EVKGKYEKPQKVSIDTGLSFLGNSAATEVTEFTALILPSDSVLKEMTSVADKNGTDIT
                     VKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGGGARGAMSFGKNKARSQAKGDVKV
                     RFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARIPAGVLLEGPPGTGKTLLAKAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAERAIIFIDEIDAVGRRRGAGMG
                     GGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPD
                     VKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVGADLENVLNEAALVAARRNKTKID
                     ASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEAGHTIVGLVLSNARVVHKVTIVPR
                     GRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRVAEEIIFNAQTTGASNDFEQATQM
                     ARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKSYSAQTAQMIDDEVRDLLNEARNK
                     AADIINDHRETHKLIAEALLKYETLDAAQIKSIYETGKMPNDPENDEAEVHALSYDEI
                     KDKMTEAKE"
BASE COUNT         1077 a          794 c          573 g          982 t
ORIGIN      
        1 agccatagca tgcatagact acaataccaa gtatagtgct gataccaaaa gcaatccacg
       61 taaataccat atactgactc ataaaggtta cacagatgat aatagctaaa attggcaata
      121 gaggcacaaa aggagtttta aactccccac gttgaggctc tccagcgttt tttcttagct
      181 taatgatagc aaaggacatg atgacaagat aagcgagagt acagatattg acaaactcag
      241 caagactggc tagggggaat attcctgcac aaatcataga taatgcacca acaactaggg
      301 ttgcatttct aggaattctt gttttttctg tgatttgaca aagggctctt ggtaaaagtc
      361 catctctact gatactgtaa accgttcttg ctaaggcata ggtcattgaa atacaaactg
      421 taattagagt taaaatggca acaattgaga cataatctgc tgcccaatat aacccaatac
      481 tccttaaagc aaaggcaact gcatcaggta catctaattt tgtatagtga acaatcccag
      541 ttaaaaccat tgtaacaata acatataaga tcgttacaat cgttaaggat aatacaatac
      601 ctcttggaat tgttttttgt ggttctttga cctcatctac tgtcatggaa atagactcaa
      661 agcccaagaa agcaaaaaac atgactgagg ctccagcgaa aatacctgac ttaccaccat
      721 aaatttggcc aaagccataa ggcgcaaaat gtgaccagtt ggctacatca ataaaaaata
      781 agcctacaat gacaaataaa gccagagctg aaaattttaa cagaactaaa aagctattga
      841 atcgcaatgc tgcctttgaa ttcatcaata caatagcagt cactaatagc atcactagca
      901 ctggaagtaa atccacatag gtcccctttt gaggatcaaa ggtaccattt aaagcattgg
      961 gcaattgtaa gccataatta gccagtaagc cttttaaata gctcccccag ccgacagcta
     1021 cacttgaaat tgctgttaaa aattccatga tgatatacca gcccacaatc caagctggaa
     1081 attcacctaa tgtcgcatag acatagctat aagcaccacc atttgctgga attcgtgaag
     1141 caaattctgc ataaaagagt gctaatatac taatagcaat agcagataga ataatagaaa
     1201 tcgtcagcgc tggtcctgca taattagcag ctcctatgcc tgtaatagtg aaaattcctg
     1261 ttcccaccat tgatcctagg cccaaaaaaa tcaaatccag catttttaag tgcctattca
     1321 tttcagtctt attaatagct tgcctttttt tacgaaagat tgtcatcttg tcactttcta
     1381 gtcttaaaat agttctactt agtttatcat agttcctgac aattgtaaat ttcactaaaa
     1441 tgaccccaat atagcctaag acctattaaa aaacgagcta ggaccaaacc cagctcatct
     1501 tatatatcaa taatgactaa ttatttattc tttagcttct gtcattttat ccttgatttc
     1561 atcataggat aaggcatgta cctctgcttc atcgttttct ggatcatttg gcattttacc
     1621 agtctcgtaa atggacttaa tttgagcagc atccaacgtt tcatacttaa gaagtgcttc
     1681 agcaatcagc ttatgagttt cacgatgatc attaataatg tcagcagcct tgttacgagc
     1741 ttcgtttaat aaatcacgaa cctcatcatc aatcatttga gctgtttggg cagaatatga
     1801 tttttcaggt gacaattgcc ctggcatcat agcatgattg ccttcatatt ggactggtcc
     1861 aagtttttca ctcataccat actctgtgac catagcccta gccatttgag tggcctgttc
     1921 aaagtcattt gaagcacctg ttgtctgagc attgaaaata atttcttctg caacacgacc
     1981 acccataagc cctgcaagct gctccttcag atcatcttta gataaaagca tttgatcttc
     2041 ctttggaagc gcaatcatat agccgcctgc tcggcctcga ggcacaattg ttaccttgtg
     2101 cacaacacga gcattggata agactaaacc aacaatagta tgacctgcct catggtaggc
     2161 aaccatttcg cgctctctct gtgaaatgct acgatccttc ttagaaggtc ctgcaataac
     2221 acgatcctct gcctcatcaa tatcactagc atcaatttta gttttatttc gacgcgctgc
     2281 aacaagggct gcttcgttta gaacattttc aaggtctgca ccgacaaaac ctggagtttg
     2341 ttgagcaaca accttcagat tgacatcctc agcaagtggc ttatttttag cgtggacgcg
     2401 taatatcgcc tcacgcccct taacatctgg tcgaccaaca agcaccttac ggtcaaaacg
     2461 acctggtctt aacaaggctg gatctaagac atcactacgg ttggttgcag caatgacaat
     2521 gatgctttca ttaccttcaa agccatccat ctcaataaga agctgattaa gggtttgctc
     2581 acgctcatcg ttaccaccac ccatgccggc accacgacga cgaccaacag cgtcaatttc
     2641 gtcaatgaaa ataatcgctc gctcagcctt tttagcatct tcaaataaag aacgcacacg
     2701 actggcacca acaccaacaa acatctcaac aaaatctgag cctgaaatgc taaagaatgg
     2761 tactcccgcc tctccagcaa cagcctttgc aagcaatgtt ttacctgttc ctggaggtcc
     2821 ctccaaaaga acaccagcag gaatgcgcgc accgagtgcc ttgtatttct taggattctt
     2881 tagaaaatca acaacctcta ccagttcttg tttttcttcc tcagcaccag ccacatctgt
     2941 aaatctaacc tttacatcac cctttgcttg tgatctagcc ttatttttac caaaactcat
     3001 ggcaccacga gcaccaccac cttgattcat gatcatcatc atgaaggctg caaaaatcac
     3061 aatcggcaga aagctcataa gaaaggtaat ccaagcccca cttgagcttt cttgttttac
     3121 agtaatgtct gttccatttt tatctgcgac agaagtcatt tcctttaata cagaatcaga
     3181 tggtaaaatt aaggccgtaa attctgttac ctcagtggct gcactattac ctaaaaatga
     3241 caagcctgtg tcaatagaca ccttttgagg cttttcatat tttcctttaa cctcaacaat
     3301 gctgccacta ggctgatagc taagtgattt aatatcacct gccttcaaat gcttaattaa
     3361 ttttgaatag ctaatttgct ggctttgtgt actagttcct cttaagtaat attgaaatcc
     3421 tgctac
//
LOCUS       DARYXS010000124         3404 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.125, whole genome shotgun sequence.
ACCESSION   DARYXS010000124 DARYXS010000000
VERSION     DARYXS010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3404
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.125"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..1982
                     /locus_tag="TV193_001805"
     CDS             <1..1982
                     /locus_tag="TV193_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1513968.1"
                     /translation="QSSKGNNGLSKSMYITFTIEAEDLKQAKSRLERMEMDVLNNFKQ
                     MGVKAYVLDGEERLKTIHDILNPNDKLVFSFEDLKYSGLTTKEYIVPPSFNFSKPTYF
                     KTGEVFAEVNFLQLLASDIKDEMLSEFLALEENMIVTFHIRAIDQMEAIKHVKRKITD
                     LDKMKLEENKKAIRAGYDMDILPSDLVTYGAEAKNLLSELQNHDEKMFLITILFMNTS
                     KSKGKLDNTVFTLKSIANRHNCSLKNLNYRQEQGLVASLPLGINEVEIERGLTTSAAA
                     IFIPFTTEELFIKGESLYYGLNALSRNIIMADRKKLKNPNGLILGTPGSGKSFAAKRE
                     ITNAFLITDDDIIIADPEAEYSPLVEALKGQVIRISPISKDYVNPLDINIDYADEDNP
                     LSLKSDFILSLFELVVGEKKLSAEEISVIDRCLPILYKTYFENPVPENMPILEDLYNL
                     LQKQEEIVGKKLAVEMEIYVKGSLNVFNHRTNVDTNNRVVCYDIKELGKQLKKIGMLV
                     VQDQVWNRVTINRASKKATRYYVDEFHLLLKEPQTANYSIEIWKRFRKWGGMPTGLTQ
                     NIKDLLASPEIENIFDNTDFILMLNQAGTDRDILAKKLNISKHQLSYVTNSGEGEGLI
                     FYGNTIVPFIDQFPKNTKLYSLITTKPEEVKKAGE"
     gene            1984..3009
                     /locus_tag="TV193_001806"
     CDS             1984..3009
                     /locus_tag="TV193_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1513969.1"
                     /translation="MSVSRSKEEFIKENTNKIICSDALETLRKIPDESISCCITSPPY
                     YRLRNYHKEGQIGRESTVEEYLDRLLQVFREVRRALKKEGTCFIVIGDSYADSGGGKG
                     QYIDPKYPKARNGSNALATENISGYKSKDLMGIPWRLALLLREDGWYLRSDIIWHKEN
                     AMPEACRDRPTRSYEHIFLLTKSPKYYYDYDAMVEPMKEVSKKRYVRGRKSDNKYLKE
                     NSGAKLQKINEARKYGEYKGDNVPQFRNKRDIWTINTTSFRGNHYATFPPKLVEICMI
                     AGCPKNEIVLDPFIGSGTVGFVALRHNRKYIGIELNEEYVNLAKNRISEEVKKFNEEQ
                     KQEVQKE"
     gene            2975..>3404
                     /locus_tag="TV193_001807"
     CDS             2975..>3404
                     /locus_tag="TV193_001807"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1513970.1"
                     /translation="MKNKNKRYKKNREKLLNQEIQSLQSQTQDNYETGSSKNQNETLL
                     KDETYDKKQFLSEKKLSNHLDNRHINNYSDRTISSYCLSDTGNINQNRSSFQAEKHKK
                     KMQKQINKFQKGEKEVYDPLSKDMDNDGVIDRYDVDFRDSK"
BASE COUNT         1306 a          479 c          689 g          930 t
ORIGIN      
        1 atcaaagcag caaagggaat aatggattat caaagagtat gtacattacc tttaccatag
       61 aggcggagga cttaaagcag gcaaaaagta gattagagcg aatggaaatg gatgtattaa
      121 acaactttaa gcagatggga gtgaaagcct atgtgttaga tggagaggaa agacttaaaa
      181 caattcatga cattttaaat ccaaatgata aacttgtttt ttcctttgag gatttgaaat
      241 acagcggact gacgactaag gaatacattg tacctccgtc ttttaacttt tccaagccga
      301 cgtattttaa gacaggagaa gtctttgcgg aagtaaattt tttacagctt ttagcatcag
      361 atattaaaga tgagatgtta tcagagtttt tggcattgga agaaaatatg attgttactt
      421 ttcatatcag agcaatcgac cagatggaag ctattaaaca tgtaaaaaga aaaataacgg
      481 atttggataa gatgaagctt gaggaaaaca aaaaagctat tcgtgcggga tatgatatgg
      541 atatcttgcc aagcgacctt gtaacttatg gtgcagaggc aaagaacttg ctatcagaac
      601 tacaaaacca tgatgaaaag atgtttctca taacaatttt atttatgaac acgagtaaaa
      661 gtaaggggaa actcgataat acggtattta ccttaaagtc cattgcaaat agacataatt
      721 gtagtttgaa aaacctaaat tatagacaag aacaagggct tgttgcaagc cttccacttg
      781 ggataaatga agtggagata gaacgaggac ttaccacaag tgcagcagct atttttatac
      841 catttacaac agaagaactc tttatcaagg gagaaagcct atattacgga ctaaatgcac
      901 taagcagaaa tattattatg gcggacagga agaaattaaa gaacccaaat ggtctaatct
      961 tagggacacc gggttctgga aagtcctttg cagccaaaag agagattact aatgcgtttt
     1021 tgattacaga tgatgatatt atcattgcag atccggaagc ggaatattct ccgcttgtag
     1081 aggcactaaa aggacaagtt atcagaattt ctccgatttc aaaagactat gtcaatccac
     1141 tggacatcaa tattgactat gcggatgaag ataatccttt gtctttaaaa tccgacttta
     1201 ttttgtccct atttgaattg gtggttggag aaaagaaatt aagtgcagaa gaaatttctg
     1261 ttatagaccg ttgtttacca attttatata aaacctactt tgaaaatcct gtgccggaaa
     1321 atatgccaat tttagaggat ttatataatc ttcttcaaaa acaggaagaa atagtaggaa
     1381 aaaagcttgc agtagaaatg gagatctatg taaaaggaag tcttaatgta tttaatcata
     1441 gaacgaatgt agatacaaat aacagagtgg tttgctatga catcaaagaa ctgggaaaac
     1501 agcttaaaaa gataggaatg ttagttgtgc aggatcaagt ttggaataga gttacaatta
     1561 acagagcaag taaaaaagca accagatatt atgttgatga atttcatctt ttgttgaaag
     1621 aaccgcaaac agccaattat tcgattgaaa tctggaagcg tttcagaaaa tggggtggta
     1681 tgccaacagg acttactcaa aatatcaaag accttcttgc aagcccggag attgaaaata
     1741 tttttgataa tacggatttt attttaatgc ttaatcaagc aggaacagat agggatattt
     1801 tagccaagaa gctcaatatc tccaagcatc agctttctta tgtaacaaat tcgggggaag
     1861 gagaaggact tatcttttat ggaaatacga ttgttccttt tatcgatcag tttccaaaaa
     1921 atacaaaact atattcacta atcacaacca aacctgaaga agtaaaaaag gcaggtgaat
     1981 aggatgagtg tgagcagaag taaagaggaa ttcatcaaag aaaatacaaa taaaattatt
     2041 tgttcggatg cacttgaaac tttaagaaaa attccagacg aaagtataag ctgctgcatt
     2101 acatctcccc catactacag gctcagaaac tatcataaag aaggtcagat aggaagagaa
     2161 tctacagtag aagaatactt ggatagattg ttacaggtat ttcgtgaagt aagaagagct
     2221 ttaaaaaaag aaggtacttg ctttatcgta attggagatt cttatgctga ttcaggaggt
     2281 ggaaagggac aatacattga tcctaaatat ccaaaggcaa gaaatggaag taacgcttta
     2341 gctacagaaa atatctcagg gtacaagtca aaagatttaa tgggaatacc ttggagatta
     2401 gcgttacttc taagagagga tggttggtat ctgcgttctg atattatctg gcataaggaa
     2461 aatgctatgc cggaggcgtg tagagataga cctactcgtt cctatgaaca tattttttta
     2521 cttacgaaat caccaaaata ctattatgac tatgatgcta tggtagagcc gatgaaagaa
     2581 gtcagtaaaa aaagatatgt aagaggaaga aaatcggata ataaatatct gaaagaaaat
     2641 tccggagcaa agttgcaaaa aatcaatgaa gcaagaaaat atggagaata taagggcgat
     2701 aatgtcccgc agtttcgtaa taaaagagat atttggacta tcaataccac atcttttaga
     2761 ggcaatcatt atgcaacatt tccaccgaaa cttgttgaga tttgtatgat tgcaggttgt
     2821 cctaaaaatg aaattgtact tgatcctttc attggaagtg gaacggtcgg atttgtggca
     2881 cttcgtcata acagaaagta cattggaatt gaattaaatg aggagtatgt aaatcttgca
     2941 aagaatagaa tcagtgagga ggtgaaaaaa tttaatgaag aacaaaaaca agaggtacaa
     3001 aaagaataga gaaaaactct taaatcaaga aatacagtct ttacaatctc aaactcaaga
     3061 taattatgaa acaggatcct caaaaaatca gaatgaaacc ttgctgaaag acgaaactta
     3121 cgataagaaa caatttttat ctgaaaagaa gttatccaat catttggata atagacatat
     3181 aaataattat tcggatagaa ctatatcttc ttattgcttg tcggatacgg gaaatataaa
     3241 tcaaaatagg tcttcctttc aagctgaaaa acataaaaaa aagatgcaaa agcagataaa
     3301 taaatttcaa aagggagaaa aggaagtcta cgatccttta tcaaaagata tggataatga
     3361 tggtgtaata gacaggtatg atgtggattt tagggatagc aaag
//
LOCUS       DARYXS010000125         3363 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.126, whole genome shotgun sequence.
ACCESSION   DARYXS010000125 DARYXS010000000
VERSION     DARYXS010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3363
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.126"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            284..>3363
                     /locus_tag="TV193_001808"
     CDS             284..>3363
                     /locus_tag="TV193_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513971.1"
                     /translation="MKLKKIIALACVGILTLHQLSPAIVYATTDTSDGIAATVNAGDT
                     AAPSAEAKLSQLMTDTQALFTDNSCSKLASGVTQEKIDTLKQKATDSTEPEKEQILGL
                     LDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKRGQPHSYFSTNYATITILN
                     NKKETVYSKEYAGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPY
                     TYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSY
                     EKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAV
                     EAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFTDESTSKLASGVTQEKIDA
                     LRKKATDSTEPEKEQILSLLDKAASLLQQFTLQGLGNGIFAQLYFYADGSYTASLVTK
                     KGQPHSYIANNYATLTILNEKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEP
                     NRFYTNHNDALKQNNTNPYTYVVRNGQLERIDDSNRTLRFLGLGNAEYATLKVDYNAS
                     TLTLKTKKAKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQALTAKTETIPFKVGYKI
                     RLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVE
                     KRLTKEKIEDFKKQDDKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTY
                     NLTNELEALELWFKIWDKYETSHQGIQLKMAIAVALEFNKPVGAWYNESRKIDPLERF
                     ATFAEAEQGNILFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVETNKPAMINRNDIT
                     KGYSLISYVMTNPETGVSVQSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVP
                     AFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNA
                     SEYERYKAEAATDKETKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLN"
BASE COUNT         1135 a          709 c          654 g          865 t
ORIGIN      
        1 atgattaaga attttccaaa cctatttatc atttctagga ttaaagaaaa tatatattga
       61 catattctga ttttttaata ttatggaata agagagacaa aatagtcaaa aaggagggat
      121 aggattttta gcaccgtaac aatatcatca ccacagcatc aagagctaag gagggtaaat
      181 agtctttcta ttttatagta tttgcgagta tagttttaag gctagctatt cttttcccag
      241 agttttgaat cactttattt tattgtaaaa ggactttata acgatgaaac taaagaaaat
      301 aatagcacta gcatgtgttg gaatattaac attacatcag ctctctccag caattgttta
      361 tgcaactact gatacttctg atggaatagc cgctacagtt aatgcaggtg atacagctgc
      421 tccttctgcc gaggctaagc tatcacaact gatgactgat acccaagcct tatttacaga
      481 taactcctgc agtaagctgg caagtggtgt cacacaagaa aaaatagata ccttaaagca
      541 aaaggcgact gactcaacag agcctgaaaa agagcaaatc ctaggtctac tagataaggc
      601 agctagccta ttacagcagt ttaccctaca agggttaggc aatggtgtct ttgctcaact
      661 ttacttctat gctgatggca gctacactgc aagtttggtc actaaaaggg gccagcctca
      721 ctcttatttc tctactaatt acgctacgat aaccattctt aataacaaga aggaaaccgt
      781 ctattcaaaa gaatacgccg gcaatgtttc tcaggtagca caaacagaag agcttgagct
      841 aaaagaaggc tattacctca tcatcaataa acaggagcct aaccgcttct acactaacca
      901 taatgacgct ctaaagcaaa acaataccaa cccttatact tatgtggtga gagatgggca
      961 gcttgagcgt attgatgata gtaatagaac gctgcgcttc cttggcttag gcaatgcaga
     1021 gtatgcaacc ttaagggttg attacaatgc ctctacccta accctcaaaa ccaagcagac
     1081 caagccacat gtttacttca gtggatctta tgaaaagctt gaggtgctgg atacagaaaa
     1141 tcaagtaatc tacacaaagg actttattgg aactcaagtc ctcgaagcta aaacagagac
     1201 tattcctttt aaagtaggct acaagatccg cttgacaggt agtgagcacc ataccagagt
     1261 gaaattctac gatgattatg cggtagaagc gccattaaca ctctctaaaa atcaagcaac
     1321 cttaaagctt cttgaccact cactagagct aatgaggtct aaaacaggct cagagcttga
     1381 gtctgaggta ctgactctat ttacagatga gtctacaagt aagctagcaa gtggtgtcac
     1441 acaagaaaaa atagatgctc ttaggaaaaa ggcgactgac tcaacagagc ctgaaaaaga
     1501 gcaaatccta agtttacttg ataaggcagc tagcctgcta cagcaattta ctctacaagg
     1561 gctaggaaat ggtatatttg ctcagctcta cttctatgct gacggcagtt acactgcaag
     1621 cttagtcact aaaaaaggac agcctcactc ttacatcgct aacaattacg ctaccctaac
     1681 cattctcaat gagaaaaaag aaaccgttta tgctaaggaa tacgtgggta atgtttccca
     1741 aacagctaaa acagaaagcc ttactctcaa ggaaggctat tacctagtca tcactaagca
     1801 ggagcctaac cgcttctaca ctaaccacaa tgacgctcta aagcaaaaca ataccaaccc
     1861 ttacacttat gtggtgagaa acgggcagct tgagcgtatt gatgatagta atagaacgct
     1921 gcgcttcctt ggcttaggca atgcagaata cgcaacctta aaggttgact acaatgcctc
     1981 taccttaact ctcaaaacca aaaaggctaa gccacatgtt tacttcagtg ggacttacga
     2041 aaagcttgag gtcttagacc taaaagacaa ggttgtctac acacaagact ttattggaaa
     2101 ccaagctcta acagccaaaa cagagactat tcccttcaag gtgggctaca agatccgcct
     2161 aactggtagt gagcaccata ctagagtcaa agcctatgat gaagaaaaca aggctgtttc
     2221 tcttagcctc cctaaaaata aggcagagat tcgaatcacc aagggtggtt tggcttctgt
     2281 atttgcacta gaggctaaag ctactaatac actcgtacaa gccgttgaaa aaagactaac
     2341 caaggaaaaa atcgaggact tcaagaagca agacgacaag cataaagcct ttattgattg
     2401 gttgctcaaa gataatgaag caatgcaatt atatcttggt gcaggctatg cccattctgc
     2461 agcacagggt ggcatgtcat cataccaatt caaaaacacc tataacctca ccaatgagct
     2521 agaagcattg gaattgtggt ttaagatttg ggataaatac gaaacctcac atcaaggtat
     2581 tcagctcaaa atggccattg cggttgcctt ggaatttaac aagcctgtag gtgcttggta
     2641 caatgaaagc cgcaagattg atccacttga aagatttgca acctttgcag aggctgagca
     2701 gggcaatatc ctatttgaag atttttacag cttaactgtt gagcaaatcc gaaatgtcgt
     2761 caatgctaaa attactgatg aggacatgaa atggttaaga caatacgttg aaaccaataa
     2821 gcctgctatg attaaccgta atgatattac taagggctat tcactgatca gctatgtcat
     2881 gaccaaccca gaaacaggtg tgagcgtcca aagctctggc ttttacggac caaatccaac
     2941 catcaaggaa gtcatcaaat atggtggtgt ctgcggtgct atgtctaaat taagtagtgt
     3001 gctagcacag gcttatggtg taccagcctt tcctattgga caaccaggtc actgtgctta
     3061 tatctactta aatgctgacc atacctatca gctcggctat gatgtctcag gctggacagg
     3121 ctgtggtaac tacaacacaa cacttcctta tgtccaaatt cataacgtct actctcttaa
     3181 tatagacgct tataatgcct cagaatatga acgatataag gctgaagcag ctactgacaa
     3241 ggagactaag cttaatcatt tagatgctgc tctaaaggca gagccattaa actataaagc
     3301 atggaatgac aagctagcat tggtagcctc agaccaaaca gcatatcaaa gcactctaaa
     3361 tga
//
LOCUS       DARYXS010000126         3301 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.127, whole genome shotgun sequence.
ACCESSION   DARYXS010000126 DARYXS010000000
VERSION     DARYXS010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3301
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.127"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(180..473)
                     /locus_tag="TV193_001809"
     CDS             complement(180..473)
                     /locus_tag="TV193_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1513972.1"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
     gene            complement(494..1369)
                     /locus_tag="TV193_001810"
                     /pseudo
     CDS             complement(494..1369)
                     /locus_tag="TV193_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677217.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1359..2609)
                     /locus_tag="TV193_001811"
     CDS             complement(1359..2609)
                     /locus_tag="TV193_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513973.1"
                     /translation="MSIDMYLSLSEEQAQSVEAVLARRQTAYQSLQETLIQLISNSPD
                     LSGRTYDSAKAYSSQVLIPLLKGCMLLDEAIITACKRLPSEYRSQVDQIDLKESDLVE
                     RIAQFDHVIGRYMDLISIEYSREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRHFD
                     TNSVHLFSTIQTLAAAVQIGMRQARTSWHAGSQVFVISEDMAWADTINSKWSKSKGLS
                     YLSDYVYDPDVLSKRAAINHSWIKTGYTMSKNFGKAVSKDYTKASFLSYGKAAKATGW
                     TSMAVDTGITSVREYNKKNSRAYGSEGKALIHASVAQIKSMGPIEGAIIGSKAGPWGA
                     LMGFVTGGINVTWGVVHPESKDNMFLWIQDKMDDVYDSIVQTDLGKGTHHAKESVKGH
                     IGRAIVRTWDFVSQSFGKGVGYDI"
BASE COUNT         1016 a          760 c          513 g         1012 t
ORIGIN      
        1 tttttttacc gattctattg aaatgctacc tttatttaat gagcataaat gctattataa
       61 cactcatttt aaagcctttt ctaaactttg gaactttaga ggtatttaag ccagagaaag
      121 tcataatctt tcaatataat catgacaatc tactgacaaa tatatctgct acagttcatc
      181 tatagcttta ttttggaaat ttctaaagta ctctcccaat cagaatacac ttctaaaaag
      241 cgttgttctt cttcgtcctt gaagccttca aagactgttt ttgcaatatc ttcatggttg
      301 aaaaaaatcg cgtcttctgg attgatccct tctggataca ttactccaac ataatcactg
      361 tagacatttt ggccattaga ttcaaatata ggaccacgtc cgacaatcat tagcttgctt
      421 gttgctccct ctagatagac aacacttcct aacggtaata attctttttg catatgatta
      481 ctccttatat cgtttatttt aataatattt ttaaacgcca tttaccgtac cactgctcat
      541 cgcttatatt aaaatgcttg cggtattctt tttgatatct aaaaaaataa taggctatga
      601 tggtattttt taacgcttga cccagtgcaa atagcatcaa aaacatgaac aatagaaaaa
      661 tccagccgta cagaaaactc aacaaaccag ggctttcctt gactagctct cctagattga
      721 gagtccagcg gttgagaaca gagaggccta ataagatacc accataagac ttaataaagc
      781 ttactagctt actgccccaa tcaggtgcta tggtgctttc ttgataaatt gctgtgcgta
      841 gctgttgaca cttatctatg acacaaacct tccacaaata aaggcaaagc aatagctgaa
      901 gcaaaaaacc gatccagcca aaagctgcaa ttgtaaggcc agcagttaaa gggaaggctg
      961 agataatagt tgtaatacta agtataataa gagtagcatt gccatataat aattgataag
     1021 cctagttagg ctttggaagg atattactaa taattaatcc aacagacata caaataaaac
     1081 aaatgataaa gtatcgactg aactgtccta atctggcaat aatctctatt gcagccaatg
     1141 aaatagcttg aactccttct gttgattatt gaaagtgttc aggtaacaca actcctactc
     1201 catatgaaat agcaaataat ggcaacatca tcaagcctgt tattctcttc catagactca
     1261 tagatgagaa tactccaatc tgcgcacctt cttctgtcaa tatactttta gacacaatct
     1321 tttttgattg ctcaaacgtc ccactaaaaa gctgatcttt aaatgtcata gcccactcct
     1381 ttaccaaatg attgactgac aaagtcccat gtccttacaa tagctcgacc gatatgacct
     1441 ttgacacttt ctttagcatg gtgcgtccct ttgccaagat ctgtctgaac aatcgaatcg
     1501 taaacatcat ccattttatc ttgtatccat aaaaacatgt tgtccttaga ctctggatgc
     1561 actactcccc aagtaacatt aatgcctcct gtaacaaacc ccattaatgc tccccaaggt
     1621 ccagctttac tgccaattat cgccccttct ataggtccca tgctcttgat ttgagccaca
     1681 ctagcatgaa taagcgcctt gccctcactg ccataggctc tactattttt cttattgtat
     1741 tcccttacac tagttattcc agtatctact gccatagaag tccagccagt cgccttggct
     1801 gccttaccat agctcaaaaa gcttgctttt gtataatctt ttgaaacagc tttgccaaaa
     1861 tttttagaca tagtatagcc tgttttaatc caagagtgat taatagctgc tctcttagag
     1921 agcacatctg ggtcgtaaac ataatcacta agatagctta accctttact ttttgaccac
     1981 ttagaattaa tcgtatcggc ccatgccata tcctctgaaa tcacaaatac ctgacttcct
     2041 gcatgccacg aggtcctagc ttgacgcatg cctatttgta ccgctgctgc caaagtctga
     2101 atagtcgaaa aaaggtgaac tgagttggta tcaaaatgcc ttagccttcg caatatctcc
     2161 tcaagacgcc gcttaacggc ccgatggagc tgctcagctg atcttaaatg agagatataa
     2221 gaatagctag gctcctctct actgtattca atactaatca aatccatgta ccgaccaatc
     2281 acatgatcga actgggcaat acgctcaacc agatcactct ccttcaaatc aatttggtct
     2341 acctgactac ggtactcact aggtagcctc ttacaggctg ttataatcgc ctcatctaaa
     2401 agcatacacc cctttaacaa aggaattagc acttgactac tataagcctt agcagaatca
     2461 taggtccgcc ctgataaatc aggactgtta gaaatcaatt ggatcaaggt ctcctgtaag
     2521 gattgatagg ctgtttgtcg cctagctaag acagcctcta cactctgtgc ctgctcttca
     2581 gataagctca aatacatgtc aatactcata gaatgtctac tcctcttgtt agttataaaa
     2641 acactgtgct attacttttc tatcactagc cagttagtgc ttctcatgct ctaatgtctc
     2701 ctaagtgctg taagcctgag cctattgcct atgtagacta ctcctcaaac aagtccgcaa
     2761 agaaaaacaa ctaaataagt cttataaaag tataatggtt tcttcataaa acacatctca
     2821 tgtccgttga tgcttgatca tattttccca tacgatcttt atcgttgtta agaacttgcg
     2881 tgatagttgc taagccaagc tttcctaagt ctgtttcaat tcatttaaca tcatgcaaac
     2941 taaagctcct acctcatatt tacagctaat agctgttcac ctagctaaat atccatcgac
     3001 caaaggccac ataacacctc ctgtaagttt taaaacatga ataggataag ccaagcagcc
     3061 actctctgag acaggcacac catctgctgc tgtatgccag aaacccttgt ctatgtatca
     3121 agcgtaacta attcgctgct agctaaggca aatattacat ttgccaaggc tgttgcgcct
     3181 tgttgagcaa ttaccgtatc atttgtaaga gtgcattatg tctgtacaga atgcctcttc
     3241 gtaaaactag cattatatca agggggcata ccttaacctt acacattcat tttctaaaac
     3301 t
//
LOCUS       DARYXS010000127         3256 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.128, whole genome shotgun sequence.
ACCESSION   DARYXS010000127 DARYXS010000000
VERSION     DARYXS010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3256
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.128"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(1..484)
                     /locus_tag="TV193_001812"
                     /pseudo
     CDS             complement(1..484)
                     /locus_tag="TV193_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515631.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(697..2259)
                     /gene="guaA"
                     /locus_tag="TV193_001813"
     CDS             complement(697..2259)
                     /gene="guaA"
                     /locus_tag="TV193_001813"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEL1513974.1"
                     /translation="MTEISMLNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHI
                     TAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPILGICYGMQLITHTLGGK
                     VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG
                     GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV
                     VWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2546..3244
                     /locus_tag="TV193_001814"
     CDS             2546..3244
                     /locus_tag="TV193_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1513975.1"
                     /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL
                     RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR
                     QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF
                     QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS
                     QYVGDRFEFYLENN"
BASE COUNT         1018 a          692 c          574 g          972 t
ORIGIN      
        1 ataatcgtat tatcctctta agttcctcaa cattataacc atcacaatct gttggcagtt
       61 tatttttttc aagccactta tcaaccactg ctattcccaa agaaattgaa aaatcttttt
      121 ctttatcaaa cttacacaat tccactgcca aagtcaatac aaaattcctg tgaatattat
      181 cgtaattttc atcaaataat tgcctttcca aacccacaat agatagccga ctaaatatgt
      241 atctccctat ttcttcgtca ataccttcag tagccttaat agcttcttgg acaacattat
      301 tccagaaagc atttttatta cgctcttcta taaaagtttt aagtttcatt ttgaaaatat
      361 cagtaatttg accaactgct ttatcaataa cctatgaaac aatattcttc atcattatga
      421 ttttctcctc gtatacataa ataattgtat ctttgctata taattgtggt atctcttcaa
      481 tcaaccaata ttgttcttaa actattccct caaaagcctt ccaccaaaac gatggaaggc
      541 ttttaaacca ttcacctaaa ttcaacaact cccttttgaa cttgctattt tagcttttta
      601 gtatcaaagc agtatcactc aagagttttt tgtttccaca aaccgcaaaa acccactgtt
      661 ttcaacactt tcatggcagt aatatatttg cttctgtcac tcccactcaa cggttgctgg
      721 tggtttgctg gtgatgtcgt agacaatgcg attaacgtgg tcgacttcat tgacaattcg
      781 aactgagatt ttctttagaa cttcccaagg caattgggca aagtctgctg tcataccatc
      841 aattgaggtg atagcacgaa tagcgatggt atagtcatag gtgcgaccat ctcccataac
      901 tccgacggaa cgaacacctg tgttaactgt aaaatattgc cacacatcac gctcaagtcc
      961 tgctttagca atttcttctc gaaggatagc atctgactcg cgaactgttt caagcttttc
     1021 tgctgtgatc tctcccatga cgcgaatggc aaggcctggg cctgggaaag gctgacgcca
     1081 gacgacttca tctggcatac caagggccgt accaagagca cgaacctcat ccttaaagag
     1141 tgtattgagg ggttcgatta attcaaactg catatcctct ggcagaccac caacattgtg
     1201 gtgagatttt atcgtttgag cagtttctgt tccagattca atgatgtctg tgtaaagcgt
     1261 tccttgtgca aggaagtcaa cgcccttaag cttgctagcc tcgtcatcaa agacgtaaac
     1321 aaactcatta ccgataattt tacgtttttt ctcaggatcc tcaacgcctg caagaagatc
     1381 taaaaagcgc tttgaggcat caacacgaat aatattgaga ccaaatcttc caccaagcat
     1441 ttccataact tggtcacctt catttttacg aagaagtcca tggtcaacaa agatacaggt
     1501 taattgatct ccgatagctt tttgtaaaag gacaccaaca actgaagaat caacaccacc
     1561 agacaaacct agcaaaacct tacgatctcc gactgtttcg cgaattttag caatttgcat
     1621 gtcaataaaa ttatccattg accaatcacc acgtccacca cagatagaga tagcaaagtt
     1681 cttcaaaata tcattaccat agacagagtg tcttacctct gggtggaatt ggataccgta
     1741 gagcctcttt tttgtatttt ccatagcagc gtaagggcaa tcgttagaat ctcctacaag
     1801 atgaaagccc tctgggattt ctgtaacagc atcaccatga ctcatcaaaa caagctgctc
     1861 atctggagtg cccgcaaata atgctgatgc agaacgtaaa cgtaatgatg attgaccata
     1921 ttctcggtga cctgcttgac cagctgggac taccttacct cctaaggtat gtgtgattag
     1981 ctgcatgcca tagcaaatcc ctaaaattgg aatccctaat tcaaagattt caggatcaat
     2041 accaaaggca tcagttgcat aaacagaatt tggcccacca gacaggacaa tcccgattgg
     2101 attgatgtca cgaagctctt gcgcagtgat gtgatggctt ttgagctcag aaaaaacacc
     2161 aaactcccga atacgtcttg caatcagttg attgtactga ctaccataat caagaacgat
     2221 aattttttga atatcattca acattgaaat ttcagtcatt ataacccttt cattatatac
     2281 cagaaccttg ttagctgata gttttcaatt aattgtagca tattttcact aaaaaggcat
     2341 tagcttttca ggtgatgtga tgaaaaaata agctttttgc agagatatta aaatgaatga
     2401 cctcaactat cttatgtatg actactattg tcagtcttag catgaaaaag ctgattgatg
     2461 atgagtgttt ttggtaataa ttgggctgct atttaggctg aaaatatgat aaaataaaac
     2521 catcatcacc ctcaaggagt aaagcatgct gccagcttat ataaaaattc atgacgctat
     2581 taaaaaagac atcgaaaaag aagtttggac tattggtagt cgcctgccaa gcgaacgaga
     2641 tttagcagaa cattttgagg tcagtcgcat gacgttgcgt caggcaataa cactgcttgt
     2701 agaggaggga attctagaaa ggcgtgttgg tagtggtact tatgttgcca gccatcgcgt
     2761 acaagagaga atgcgtggga ccactagctt tacagagatc gtgaattctc agggacgtaa
     2821 gccatcttca aaactgattt cctatcaacg tcagctagca agtgatacag aaataaatca
     2881 attgcactta gaagaatcag attacgttat tcgaatggag cgcattcgtt atgcagataa
     2941 ggttccctta gtttacgagg tagcatctat tcctgagaaa tttattaaaa atgtcaaaaa
     3001 aactgatatt acagagcact ttttccaaac cctaacctca aacggttatg aaatcggcaa
     3061 aagtcaacaa accatttacg cgaaaatagc cagtgagcgt gtcgcctctt atctagaggt
     3121 cgctaagggg catgctattt tagcattgac tcaggtttcc ttttttacag acggtaggcc
     3181 ctttgaatat gtgcgtagcc aatatgtagg tgatcgcttt gaattttatt tagaaaataa
     3241 ttaatcataa gcaatg
//
LOCUS       DARYXS010000128         3255 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.129, whole genome shotgun sequence.
ACCESSION   DARYXS010000128 DARYXS010000000
VERSION     DARYXS010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3255
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.129"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..1555)
                     /locus_tag="TV193_001815"
     CDS             complement(<1..1555)
                     /locus_tag="TV193_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1513976.1"
                     /translation="MFYLKLAWNNLRKSLSVTAPFLLASTVLYMLNCIVLIIMMSPVS
                     ESMRHGFMLLGLAIFVLIIFATIMEIYSYNFLLKQRSREFGLYNILGMNKKQVGLVST
                     IELVFMYLGTVVVGSILSAIFSHVFYLIFANLVGAVHLELQINPVAFIYTTLIFAAIF
                     GLLEVVGLIKIRKTSPLMLFRHKEQGEKEPKGNLLLAALSIILLSIGYYISLSSTKLT
                     ALDTLYRFFIAVIIVIIGTYLFYISFMTWHLKRRRQNKAYFYQPEHFVSTSQMIFRMK
                     QNAVGLANITLLAVMAFVAIATTTALYANSEAMSNQLFPKNTHINFDNSEIDNQKEVF
                     NRLIVEKTNKPASDFLVYYSSMVSFEVSQKETIVVTKESLLNPSPVTTGYVYLVTQDD
                     FRALGNQLPELKDNQTAFFKQRGDSQLRQLDILGKSYTNVKNLTSVTFPEAANTYNGA
                     VLVVKDMETLKDIQDSIQSINHTGGRASISAYADLTKADLRSISDDKGIISDGDTVIG
                     HIETKKEYLR"
     gene            complement(1558..2310)
                     /locus_tag="TV193_001816"
     CDS             complement(1558..2310)
                     /locus_tag="TV193_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1513977.1"
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESG
                     SGKTTLLNILATLEKPTKGSVLLNGTDITKIKEGDLANFRLQNLGFVFQDFNLLDTLS
                     IRDNIFLPLVLNRKPFKEMERRLNIIAPKLRIETLLDKRPFEISGGQKQRVAIARSLI
                     TNPQLLLADEPTAALDYRNSEDILNLFEAINLDGQTLLMVTHSANAASHAKRVLFIKD
                     GRIFHQIYRGNKTNLEFSKDISIAMAGLLGGE"
     gene            2641..3120
                     /locus_tag="TV193_001817"
     CDS             2641..3120
                     /locus_tag="TV193_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEL1513978.1"
                     /translation="MAKKIKKTLGTVGKLFSIIPDTTEIIGKTIDNTRPIIEKHMEQK
                     HEKEMQLTLLDDVINLPVDKAQKHLEQLGFVVALLPVKPSKKWIHASLNEVVSMSPKP
                     GKHKLGSLVKLYYVTVDVLEKSQAILDQETLKAVERNQKIADTIEAVKQIKLPFKKR"
BASE COUNT         1036 a          605 c          609 g         1005 t
ORIGIN      
        1 atcggaggta ttccttttta gtttcgatat gacctataac agtatcacca tcactaatga
       61 ttcccttatc atcactaata ctcctaagat cagccttagt taaatcagca taggccgaaa
      121 tgctggccct tccgccagta tgattaatgc tttgaatgct atcttgaatg tcctttagtg
      181 tttccatatc tttgaccaca agaactgcac cattataagt gttagctgcc tctgggaagg
      241 ttactgatgt taaatttttg acattggtat atgatttgcc caaaatatcc agctgtcgta
      301 attgactatc ccctctttgc ttaaagaagg cagtctgatt gtcctttaat tcaggcaatt
      361 gattgcccaa ggcgcggaaa tcatcttgag tgactaagta gacatagcct gtagtgactg
      421 gactaggatt tagcaaggat tctttggtta ctacaatggt ttctttttgg gatacttcaa
      481 aagaaaccat gctactataa tagactagaa aatccgaggc aggcttattg gtcttttcaa
      541 caataagtct gttaaaaacc tctttttgat tgtcaatctc tgaattatca aaattaatat
      601 gagtattttt aggaaaaagc tggttagaca ttgcctcgct attagcataa agcgcagttg
      661 ttgttgctat tgcaacaaag gccataacag ctaagagggt aatatttgcc aagcctacag
      721 cattttgctt cattctaaaa atcatctgag aggtgctgac aaaatgctct ggctggtaaa
      781 aataagcctt gttttgacga cgacgcttta agtgccaagt cataaaggaa atgtaaaaga
      841 gataggtccc gataataacg ataataactg ctataaaaaa ccgatataaa gtgtctaatg
      901 ctgtcagctt tgtcgatgat aaggagatgt aatagccaat actaagcaat atgatggata
      961 aggctgctag taataaatta ccctttggct ctttttcacc ctgttcttta tgacgaaaga
     1021 gcattaaggg agaggtcttt ctgattttaa tcaagccaac aacctctaat aaaccaaaga
     1081 tagcagcaaa gattaaagtg gtgtaaataa aagcaacggg attgatttgt aattctaaat
     1141 ggactgctcc gaccagatta gcgaaaatca aataaaagac gtgtgaaaaa atagctgata
     1201 ggatacttcc tacgactact gtccctaagt acataaaaac aagctcgatc gttgagacta
     1261 aaccaacctg ctttttattc attcccaaaa tattgtacag accaaattct cgacttcttt
     1321 gctttagtaa aaaattatag ctataaatct ccataatagt ggcaaagatg attaaaacaa
     1381 agattgctag tcctaatagc ataaacccat gtctcatcga ttctgatacg gggctcatca
     1441 tgataatcaa gacaatacaa ttgagcatat ataaaacagt gcttgccagt aaaaaaggag
     1501 ctgtgacgga taaggacttt cgtagattat tccaagctag tttgagataa aacatcttta
     1561 ttcacctcct aaaagaccgg ccatggcaat cgagatgtct ttgctaaatt ctaaattcgt
     1621 tttatttcca cgatagattt ggtggaaaat acggccgtcc ttgataaaca gtactcgctt
     1681 agcatggcta gcagcattgg cagagtgtgt taccatcaag agtgtctgac cgtctaggtt
     1741 aatggcctca aaaagattga gaatatcctc tgaattgcgg taatcaagtg ctgctgttgg
     1801 ttcgtcagct aataataatt gcggattggt gattaagctt cttgcaatag caaccctttg
     1861 cttttgacca ccagaaattt caaatggacg tttatctaaa agcgtttcaa tgcgcagctt
     1921 aggggcaatg atgttgagcc gtctttccat ttctttaaat ggcttacggt ttaaaacaag
     1981 gggtaaaaag atattatctc tgatcgatag ggtgtctagg aggttaaaat cctgaaaaac
     2041 aaagcctagg ttttgaagtc ggaaattagc taggtcaccc tccttaattt ttgtaatgtc
     2101 agtgccattc aataaaacag atcccttggt tggtttttcc agagttgcca gaatatttaa
     2161 tagggttgtt ttccctgagc ctgactctcc catgatggca ataaactcac ccttgtcaac
     2221 cttaaaatca acatcttgta aggctctagt ttcttccttt gaaaagcgtg tccgaaaaac
     2281 cttctctaaa tgattaattt ctaataacat atgaaactcc tttgtgtcta ttatactctt
     2341 ttagctttaa atatagccac tatcgtgacg tatttagcta gtgatgcatt tagtgccttt
     2401 tgtcagcctt aaccactcct tctttcatga agcagcccag ctctcaacaa gaatcgtctt
     2461 agctgactga acctattgct ctaaactctt ttttctttac agcttatagt ttaccctaat
     2521 taatagtctg gttagcttac aagatttgat gggtgactta cagatttgta agttttataa
     2581 catcattttt cttatcattt tgatataatg aaaggagaat tctatttagg agaagcgtca
     2641 atggctaaga aaatcaaaaa aacgctaggg actgtcggaa agctgttttc cattatccct
     2701 gataccactg aaattatagg aaaaacgata gataacaccc gtcccattat cgaaaagcat
     2761 atggaacaaa agcatgaaaa ggaaatgcag ctaacgcttt tagatgatgt gattaattta
     2821 cctgttgata aagcgcaaaa gcatctggaa cagctaggtt ttgttgtcgc actattgccg
     2881 gtcaagccta gtaaaaaatg gatacatgct agcttaaatg aggttgtttc catgtcacct
     2941 aagcctggaa agcataagct gggaagctta gtaaagcttt attatgttac tgtagatgtc
     3001 cttgagaaaa gtcaggctat tttagatcaa gagaccctaa aggctgtcga acgaaatcaa
     3061 aaaatcgctg ataccatcga agctgttaag caaatcaagc ttccttttaa aaagagataa
     3121 ggctatactg taaaaaataa gctgataccg ttaggatcag tttatttttt atgttgtgac
     3181 tttaagtcta tctcgcttag caggtgccaa acaaataaac cacccgttat gtaccgacct
     3241 tcaatggtta aagtt
//
LOCUS       DARYXS010000129         3199 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.130, whole genome shotgun sequence.
ACCESSION   DARYXS010000129 DARYXS010000000
VERSION     DARYXS010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.130"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..156
                     /locus_tag="TV193_001818"
     CDS             <1..156
                     /locus_tag="TV193_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HEL1513979.1"
                     /translation="WYKSKQTDLNAAEVQDLALEMSYKEVVDGNNAAITGQWSDSPQI
                     ILDGGNQ"
     gene            153..1268
                     /locus_tag="TV193_001819"
     CDS             153..1268
                     /locus_tag="TV193_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1513980.1"
                     /translation="MTENIPLRVQFKRMTADEWARSDVILLEGEIGFETDTGYAKFGD
                     GRSRFSELKYLTGPKGPKGDDGPQGKTGDTGPQGPAGKPGTTDYNQLQNKPNLDAFAQ
                     KKETDSKIAKLVSSKADKSAVYLKAESKIELDKKLSLTGGVMTGQLKFKPAATVAYSS
                     STGGAVNIDLSSSRGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYKGTTNAVN
                     IAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEASYDENAAA
                     LSIDIVKKQKGGGKGTAAQGIYINSTSGTTGKMLRIRNLNDDKFYVKPDGGFYAKETS
                     QIDGNLKLKDPIANDHAATKAYVDGEIKKIKALLTAK"
     gene            1287..>3199
                     /locus_tag="TV193_001820"
     CDS             1287..>3199
                     /locus_tag="TV193_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1513981.1"
                     /translation="MSRDPTLTLDESNLTIGSDGRVHYTFTASQDNQKVRLASNCLGT
                     TRFNQVMIERGDKATDYVAPVVVEGSGESTGVFKSLEEMLSGLQSINLELTDTKNSNL
                     WSKIKLNNRGMLQTYFDTTIKNEILTTAQGIRETISDTERGLKSEFLKTVQGQRIQLE
                     SLLEQKTAQIGLTVDGLRLDLNKAGKQTASLQASIEGLRQDYQDADRQLSASYQSGIS
                     GLKTQLANDKIGLQAEIKLSAQGLSQKYDDELRKLYAKITTTSSGTTEAYENKLEGLR
                     AEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIRDRTGAVSRVQQDLASYQRRLQ
                     DTEKNYSSLTQTVSGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSIINESGDSI
                     KLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNTTVNGAFGAKLGEFIK
                     LKADQIIGGTIDAAKIRVINLNASSIVGLDANFIRAKIEHTITSLLEGKVIRARNAAM
                     MIDLSNSKIDFNSNATINFNSSNNALVRKDGTHTAFVHFSTATPKNYTGSALYASIGI
                     TSSGDGINSASSGRFCGARFFRYARGYEHTALVDQAEIYGDDIVFSDDFNIDRGFKMR
                     PSLMPKMVDLNKM"
BASE COUNT         1011 a          644 c          773 g          771 t
ORIGIN      
        1 tggtacaaat ctaagcagac ggatttaaat gcggcagagg tgcaggattt agctctggag
       61 atgtcttata aagaggtggt tgatggtaac aatgccgcga taacagggca gtggtcagac
      121 agcccacaaa tcatcttaga tggaggtaat caatgacgga aaatatacca ctacgagtcc
      181 aatttaagcg catgactgct gatgagtggg ctcgtagtga tgttatctta ctggagggtg
      241 agattggctt tgagactgat actggctacg ctaaatttgg tgatggtcgc agtcgcttta
      301 gtgagcttaa gtatcttact ggtcccaaag gtcctaaagg agacgatggt ccccaaggca
      361 agactggcga tacaggtcct cagggccctg ctggcaagcc tggaacgaca gattataatc
      421 aactccaaaa taaaccaaat ctagatgcgt ttgcacaaaa aaaagaaact gatagtaaaa
      481 tcgccaaatt agtatcaagc aaagcagata aaagcgctgt ttacttaaaa gcagagtcaa
      541 aaatagagct agacaaaaaa ttgagtttga caggtggcgt tatgacaggc caactaaaat
      601 ttaagccagc cgccactgtt gcttattcct cgtcaacggg tggagcggtc aatattgact
      661 tgtcgtctag cagaggtgct ggtgttgttg tctattctaa caatgatacc agtgatgggc
      721 cgttaatgag cttgcggacg ggtaaagaga ccttcaatca atcggcgctt tttgtcgatt
      781 ataagggaac aacaaatgcc gttaatattg cgatgcgtca gccaaccacc cccaattttt
      841 catcggcgct taatattact agcggcaatg aaaatggtag tgcgatgcaa attagaggcg
      901 ttgaaaaagc attgggaacg ctcaaaatca cgcacgaaaa cccaaacgtt gaggcaagtt
      961 acgatgaaaa cgctgcagcg ttatctattg atatcgttaa aaaacagaaa ggcggtggaa
     1021 aaggtactgc tgctcaagga atctacatta actcaacatc aggcacaact ggtaaaatgc
     1081 tcagaatcag aaaccttaat gatgataagt tctacgtcaa gcctgacggt ggtttttatg
     1141 ccaaggaaac ttcgcagatt gatggcaacc tgaaactcaa ggatcccata gcgaatgatc
     1201 atgcggcaac caaagcttat gttgatggtg aaatcaaaaa aataaaagca ctcttaacgg
     1261 ctaagtaaat gtaaaaagga ggagatatga gcagagaccc aacattaaca ttagacgagt
     1321 caaatttaac gatcggctca gatggacgtg tgcattacac gtttacggct agtcaagaca
     1381 atcaaaaagt cagattagcc agcaactgtc taggaacaac tcgctttaat caggttatga
     1441 ttgagagagg cgacaaagcg actgactatg ttgcgcctgt tgtcgttgag ggcagcggtg
     1501 agtcgacagg tgtgtttaaa agtcttgagg agatgcttag tggtctacag tctattaatt
     1561 tagagctgac agataccaaa aactccaatc tttggtcaaa aatcaagctt aacaatcgtg
     1621 ggatgttaca gacatacttt gacacgacta ttaaaaatga gattttaaca acggctcaag
     1681 gtatcagaga gactatatcc gacaccgagc gaggacttaa gtccgagttt ttaaaaacgg
     1741 tacaaggtca gcgcatccaa ctcgagagct tgctagagca aaagacggct caaattggct
     1801 taacagtcga tggcctaaga cttgatttaa ataaagcagg caaacagaca gctagtttac
     1861 aggctagtat cgagggattg agacaagatt atcaagatgc tgatagacag ctatcagcta
     1921 gttatcagtc tggtattagc ggcttaaaaa ctcaactggc caatgacaaa atcggtctac
     1981 aagctgagat taagctgtca gctcaaggct tgtcgcaaaa gtacgacgat gagctgcgca
     2041 agctgtatgc taagattacc accacctcat caggcacgac cgaagcgtac gaaaacaagc
     2101 ttgagggctt gcgtgctgag tttacccgta gcaaccaagg catgcggaca gagcttgagt
     2161 cgcagatcag tggcctaaaa gcagtacagc agtcaactgc aaaacaaatc tcacaagaga
     2221 ttagagacag gacaggagct gttagtcgtg tacaacagga cttagctagc tatcagcggc
     2281 gattgcagga tactgagaag aattactcta gcttaaccca gaccgtcagc ggtctgcaaa
     2341 gcgatgtcgg ctcaccaaca ggtaaaatcc aatcacgcct tactcaacta gcaggacaaa
     2401 ttgagcagcg ggttactaga gatggtgtca tgagtatcat caacgagtca ggcgatagca
     2461 ttaagctagc gatccaaaag gctggtggga ttgatgctaa gatgagcgct aaagagatta
     2521 tctcagcgat taatcttaat ggctatggcg tcagaatctc cggtgagcgt attgctctgg
     2581 acggtaatac gaccgtcaat ggggcttttg gggctaagct cggtgagttt attaagctca
     2641 aagctgatca aatcatcggt ggtacgattg acgctgctaa gattagagtg atcaatctta
     2701 acgctagcag cattgttggt ctagacgcta actttatcag agccaaaatc gagcatacga
     2761 tcactagctt gcttgagggt aaagttatca gagctcgcaa cgcagcgatg atgattgact
     2821 tgtcaaactc taagattgac tttaacagca acgccaccat caactttaac agtagcaata
     2881 acgcgcttgt ccgtaaagac ggtacccaca cagcctttgt gcattttagc actgccacgc
     2941 caaaaaatta cacaggatca gcactttacg cctcaatcgg gataacctca tctggtgacg
     3001 ggattaatag tgcgtcgagt ggtcgttttt gcggtgctag gttttttaga tatgcacgag
     3061 gttacgagca cactgcactt gttgaccaag ctgagattta cggtgatgat attgtcttta
     3121 gcgacgattt taacatcgat cgtggcttta agatgcggcc tagcctaatg ccaaaaatgg
     3181 tcgatctcaa taagatgta
//
LOCUS       DARYXS010000130         3196 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.131, whole genome shotgun sequence.
ACCESSION   DARYXS010000130 DARYXS010000000
VERSION     DARYXS010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3196
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.131"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(97..1722)
                     /gene="groL"
                     /locus_tag="TV193_001821"
     CDS             complement(97..1722)
                     /gene="groL"
                     /locus_tag="TV193_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEL1513982.1"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGIGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TV193_001822"
     CDS             complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TV193_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEL1513983.1"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGDFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
     gene            2383..3196
                     /locus_tag="TV193_001823"
                     /pseudo
     CDS             2383..3196
                     /locus_tag="TV193_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          980 a          720 c          605 g          891 t
ORIGIN      
        1 agggataatc atatcacctt aacgtcaggg gagtctttat aagttatttt tatatcctat
       61 gacagacaca ctagtctatc ctaacaggcc ttcttgttag aagccaccca tcatgcctgg
      121 atccattcct tgcggcattg ctggtgcagc aggctctggc ttagtggcaa caacagcttc
      181 ggtggtcagg ataagacctg caacagaggc tgcattttga agtgctgaac gtgttacctt
      241 gactggatca atgatacctg tagcaatcat atcaacccat tcaccagttg ctgcattaaa
      301 accaatacca gcagcactat ttttcagctt atcaataatc actgaacctt catagccagc
      361 gttgtaagca atttgacgca caggctcttc aagcgcacga agcacgatat tgcgaccagt
      421 tgctgcatca ccatcaagct caagggctgc aaccttatcc atgacattga taagagcagt
      481 accaccacct gcaacgatgc cttcttcaac cgcagcgcgt gttgcattta gcgcatcctc
      541 aatacgaagc ttcatttctt ttagctcggt ttcagtagct gcacccacct tgataactgc
      601 aacaccacct gctaattttg ctaagcgctc ttgtaatttt tcacgatcaa attcagatgt
      661 ggttgtttct aattgtgatt tgatcaggct aacgcggttt gaaatagctt ctgagctgcc
      721 tgcaccttct acaatcactg tattatcctt gtcaacagtt actttagccg cttgtccgag
      781 ggcagccatt gtagcatcct tcaattcaag accaagatcc tcagtgatga ctgtaccacc
      841 agttaagaca gcaatgtctt caagcatcgc tttacgacga tctccaaagc caggcgcttt
      901 aaccgctaca acattgaagg taccacgaat tttattaagc actagggtcg gaagggcttc
      961 gccatcaaca tcatcagcaa tgatcaacaa tggacggcta gtcttaagca cctcctcaag
     1021 caatggaaga atgtcttgga tattagaaat tttcttatca gtaatcagga taaatgggtt
     1081 ttcaagatca gcaaccattt tttcattgtc agtgaccatg tattgtgaca aatagccgcg
     1141 gtcaaactgc attccctcaa caacctcaag ctctgtttcc ataccacgtg attcctcaat
     1201 agtaatcaca ccatcatttc ccacgcgctc catagcttca gaaatatagt caccaacctt
     1261 ttcagaacgt gatgacaccg aagctacttg agcaatagct tcttttccag atactggttg
     1321 agcaacagcc tttaaggcct cgacagctgt cgttgtcgct gcttcaatcc cacgacgaat
     1381 accaattggg ttagcacctg ctgttacatt tttaagccct tcacgcacaa tcgcttgggt
     1441 caaaacagta gctgttgttg tcccgtcacc agcaatatca tttgtttttg aagctacctc
     1501 tgatacaagc ttagccccca tattttcaaa atgatcttct aattcaatct ctttggcaat
     1561 cgttacacca tcatttgtga tcaaaggaga accaaaggcc ttttcaagga ctacattacg
     1621 ccctttaggg ccaagggtta ccttaacggt atccgccaaa atatcaacac cacgtaccat
     1681 gctttcacga gcatctgctg aaaattttat atcttttgcc atgttatttc ctctattcct
     1741 atttgaatgt atatctgtta atcctacctg aaatgatagg gattcacaat taagctaaaa
     1801 ctgcaagaat gtcagcttca cgacagatga caagctcttg atcgccatct ttaacctcta
     1861 agcctgatcc atattcaacc aaaaccttgt cacctacagc cacacttggt ggaacaatgt
     1921 ctccagtaat agtacgaata cctgtctcac taacagctac aactgtccct actttagtgg
     1981 cttctttgtg actagcagca agaacaaagt caccgacggt ctgctctttt tctgcttcaa
     2041 attttaggac cacacgatct cctaacggtt ttaacatgaa tagtacctcc aataatgact
     2101 agattatcta ttttgttagc actcttgttt tatgagtgct aactttcttc tctattttat
     2161 cacttggtca aaaatagtca agaaaaaaag tctaggaaaa aagaaaagac ccagctggtg
     2221 acccgcaccc caaaagttag acagaaaatc taccaatggg gtgcttttta tatgaaatta
     2281 agttacgatg ataaattaag aatatatgaa ctaagaaaaa atgggatgtc ttgttcccgc
     2341 attggtcaac agtatgatat tcaggtttct aatctcaaat acatggtaaa gcttatggac
     2401 agatatggag ttgagattgt tagaaagggt aaaaataagt attatcctcc agaattaaaa
     2461 caagaaataa ttgataaagt tcttcttgaa ggtcagtctc aactgtctgt ctctcttgag
     2521 tatgctctcc caaatgctgg tatgcttccc aattggatag cgcaatacaa gaaaaacggg
     2581 tatactattc ttgagaaaca aagagggaga ccaacgaaga tgggccgtaa accaaagaaa
     2641 acttgggaag aaatgacaga gctagagcgc cttcaggaag agctagaata ccttagaacg
     2701 gagaatgctt atctaaaaaa gttgagggag cttcgtttac aggacgaagc cagagaatga
     2761 gaaaggcaga aacaattaga gagatggtcc aagaaggatt ccgattaaac ctcctacttg
     2821 agatcgctaa gatggctcgt tcaacctatt attatcaagt caagcaattg gataagtcag
     2881 ataaagatga agcaatcaac tctgaaatca aagcgattta tgaggagcat aagggaaact
     2941 atggttaccg tcgcattcat ttagaactca agaatcgtgg gtttatcgtc aatcacaaga
     3001 aagtgcaacg cttgatgaaa gagatgagat tagctgctcg aattcgtcgt aaacgcaggt
     3061 attcctctta caaaggcgag actggtaaga aggctgataa tctgattcaa cgccagtttg
     3121 aagctgctaa gccatatgaa aaatgttata ccgatgtgac agagtttgct ttaccaaaca
     3181 acgatgaaaa acttta
//
LOCUS       DARYXS010000131         3158 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.132, whole genome shotgun sequence.
ACCESSION   DARYXS010000131 DARYXS010000000
VERSION     DARYXS010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3158
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.132"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            141..211
                     /locus_tag="TV193_001824"
     tRNA            141..211
                     /locus_tag="TV193_001824"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:173..175,aa:Cys,seq:gca)
     gene            complement(318..1385)
                     /locus_tag="TV193_001825"
     CDS             complement(318..1385)
                     /locus_tag="TV193_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1513984.1"
                     /translation="MAKFRKRGDKWSYRIYYTDSQGNKREKSKGGFKTKALASAAAIK
                     VEAELNKDIDDISLYDFCKEWAKIYKRPHVVDKTWETYTKNLKHIKKYFGDIKLNNVT
                     HTFYQKTINEFAKKYAQETLEKLHYQIKGAVNVAVRDGLIKTNFAEGAIVKSQKEARA
                     KEFDFLEEDEYLNLIKVTSEKYQYVSYFTLYIIAVTGLRFAEATGITWSDIDFEKGFI
                     DINKSFDYSKTQEFKETKNEQSKRQIPIDQQTIKLLRAFKENYYNENKLNRVLYGASN
                     SLCNRLVKKIVGRPVRNHSLRHTYASFLILKGVDLISISQLLGHENLNITLKVYAHQL
                     DKLKEKNNQAIKDIFGNLTDF"
     gene            complement(1512..1787)
                     /locus_tag="TV193_001826"
     CDS             complement(1512..1787)
                     /locus_tag="TV193_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1513985.1"
                     /translation="MRYKVLFTKKAKKQLKKLDRSTAKQLYQWIMTNLDGTDNPRRYG
                     KALQANRTGEWRYRLGNYRILAEIIDDEVVIEVFKIEHRSSVYKIKR"
     gene            complement(1777..1995)
                     /locus_tag="TV193_001827"
     CDS             complement(1777..1995)
                     /locus_tag="TV193_001827"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEL1513986.1"
                     /translation="MIAMTLNLEKDDAYIADYIKENNIDTSNLTVDQFLEIIEDAKDL
                     YELRKAKAEDDGTRFSMEDVAKELGFAL"
     gene            complement(2011..2532)
                     /locus_tag="TV193_001828"
                     /pseudo
     CDS             complement(2011..2532)
                     /locus_tag="TV193_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059208.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            2921..3127
                     /locus_tag="TV193_001829"
     CDS             2921..3127
                     /locus_tag="TV193_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1513987.1"
                     /translation="MLNIDKVRKEKGVAIVDMADFLGVRAQTVSDKLRGTYDFKFTEA
                     LALQQKFFPEYDLEYLFNKAVDTA"
BASE COUNT          924 a          580 c          547 g         1107 t
ORIGIN      
        1 ttttaatatt attaaaaatg attttctgat ttaaactcta aaaaataaca taaaccgaaa
       61 aaaggagcag cctgctaaaa aatagctgct atttttatct tgacgaatgc tatcaactag
      121 ggtaaaatag ttcttgttat ggcggtatag ccaagtggta aggcacggct ctgcaaaagc
      181 ttgatcgtcg gttcaaatcc gtctaccgcc ttttatatac aaacgaatcc ttgattaacc
      241 tcgtaaaaac gttgttaaat caaggttttt attttttgtg gcaggataaa aaaagagaaa
      301 aaaagaaata aagtcggtca aaagtcggtc aaatttccaa aaatatcttt tatggcctga
      361 ttgttctttt cttttagctt atctagctga tgggcatata ccttaagcgt aatgttcaaa
      421 ttctcatgcc caagcaactg agatatggat attaggtcaa caccctttaa gattaaaaaa
      481 gatgcgtaag tatgacgtag agagtgattg cgtacaggac gaccaacaat ttttttaacc
      541 aatctattgc agagtgaatt agaagctccg tagagcaccc tatttagctt attttcatta
      601 taataatttt ctttaaatgc tctaagcaat tttatagttt gctgatcaat gggaatttgt
      661 ctttttgatt gctcgttttt tgtttcctta aattcttgag tttttgagta atcaaacgat
      721 ttattaatat ctataaatcc cttctcaaag tctatatcgc tccaagttat cccggtcgct
      781 tcggcgaatc gtagtccagt cactgctatg atgtataaag taaaatagga aacatactgg
      841 tatttctcac tcgttacttt gattagattt agatattcat cttcttcaag gaaatcaaat
      901 tcttttgctc tagcttcttt ttgagatttt acaatcgcac cttcggcaaa atttgttttg
      961 ataagcccat ctctaactgc tacattaaca gctcctttta tttgatagtg gagtttttcg
     1021 agtgtttctt gggcatattt tttggcaaat tcgttgattg ttttttggta aaaggtatgc
     1081 gttacattat taagcttaat atcaccaaaa tattttttga tgtgcttaag atttttagtg
     1141 taagtttccc aagttttatc gacaacatgc ggacgtttgt agattttagc ccattccttg
     1201 caaaaatcat aaagtgatat atcatcaata tctttattta gctcagcctc gactttaatc
     1261 gcagctgcag aagccaatgc ttttgtctta aaaccacctt tggatttttc ccttttgttc
     1321 ccctgactat ctgtgtagta aatacgataa gaccacttgt cgccgcgttt tctaaatttt
     1381 gccattgtta attacctcat ttttatgtta aaatgggtac agtaaagaga cctactgcga
     1441 agcaggtttt ttactataca ggatttgcct cacgctcaga ctcgccaaag tttgagagcg
     1501 tggggctttt tttaacgttt gattttatag actgagcttc gatgctctat tttaaaaact
     1561 tcgatgacaa cttcgtcatc aataatctca gctaaaatac gatagtttcc taaacgataa
     1621 cgccactctc ctgtacgatt agcttgtaaa gcttttccgt atctccttgg gttatctgtg
     1681 ccatcaaggt tagtcattat ccactgatag agttgtttag cagtagatct atctaatttt
     1741 ttgagttgtt ttttggcttt tttagtaaac aatactttat aacgcaaaac ctagctcctt
     1801 cgctacatct tccatgctaa atcgtgtccc atcgtcctca gccttagctt ttctcaattc
     1861 gtacaaatct ttagcatctt caatgatttc caaaaactgg tcaactgtta gattggaggt
     1921 gtcaatgtta ttttctttga tgtaatctgc gatataagca tcgtcttttt caaggtttaa
     1981 tgtcattgca atcatagtat ttttctcctt ctatatttct actggtgtaa agctgccgac
     2041 gacatcatag attttgatgt aagtatcttc tgctggcggg tagtcgataa agatatcatt
     2101 gtatttttta ttgagagata ctaatctaag cccgtcttcc tctgtgtata cttttttaaa
     2161 ataggtctgt ccgttatgca caactataca tagctgaccg gcatatgctg acatgccccg
     2221 atctacaata tagagcatat ctccttgctc gtactttggt agcatactat cgccccgcac
     2281 tccaattgca tagtcgtagt gaggtggttc ttcgtcagtg tagacagtat atgtgtcata
     2341 ttcatctgct tcaaatccac gaccaaagcc acttgcggct gccgcgtaag ttacgccttg
     2401 aaccgaaaat aattcttcat gcgtagaaac aactttattt tgttcttcca attgctcctt
     2461 ggcaaagtca aggacttttt cttgtctagg ttgttctagt tggttgtaga tggacactat
     2521 ttcagatgta ttttttgggg catctagcag agacgaaaac acctcgggtc tgatacctaa
     2581 agctgagcaa atttttatgg cattctcgac gttagcattc attattcctc gctctaatat
     2641 cgagcgaacc gttgagtaag gcatgttgtt ttcttctgca aaagatttta cagagctata
     2701 acgagaaagt ataagatgtt ttagattttc ttcattcatg gctgcctctc tttctgattt
     2761 cattataaca cacgattttt cgtttgtcta acaaaaaaac actaagaaat acgaatttta
     2821 gtattgacaa acacgaaaaa aagtattaaa cttgtatcaa gctcagatga gcttaacttt
     2881 aaaaccaaaa acacgaaaaa tcgtgttaga aaggagttat atgttaaata ttgataaagt
     2941 gcgaaaagaa aaaggcgtag caatagtaga catggctgat tttcttggcg taagagctca
     3001 aacagtaagc gataaattgc gcgggactta cgattttaaa tttactgagg ctttggcgtt
     3061 gcaacaaaaa tttttcccgg agtacgattt agaatatctt tttaacaaag cagtagacac
     3121 tgcttaactt taaaaccaaa aacacgaaaa atcgtgtt
//
LOCUS       DARYXS010000132         3149 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.133, whole genome shotgun sequence.
ACCESSION   DARYXS010000132 DARYXS010000000
VERSION     DARYXS010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3149
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.133"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(153..356)
                     /locus_tag="TV193_001830"
     CDS             complement(153..356)
                     /locus_tag="TV193_001830"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513988.1"
                     /translation="MKRYIIEQLANETDTITIMFTNGKQHTFCQVANECPDNPNIIEL
                     KLSDAQYIVLVNLDQVTYISHHS"
     gene            416..877
                     /locus_tag="TV193_001831"
     CDS             416..877
                     /locus_tag="TV193_001831"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513989.1"
                     /translation="MQANRIFYGKEKPTNAVAGDCWFRDNELMILKDNWEASVNNLKS
                     PKVIGEIEIDLEQHDVLLTARGSRPPLLMIDGIMLGGVSKVIIINELSESCAIVSLNE
                     YIKENLFPFDDFESLQRLFQKGHQKLSVRELCLEKRLGEHSYQDHRKSCDE"
     gene            1018..1746
                     /locus_tag="TV193_001832"
     CDS             1018..1746
                     /locus_tag="TV193_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEL1513990.1"
                     /translation="MNELINITVNDNHEPVVSGRDLYKVLEIKTQYTKWLERMSEYGF
                     VENEDFMAISQKRLTAQGNQTEYTDHILKLDMAKEIAMLQRNEKSKQVRKYFIQIEKD
                     FNSPEKIMARALLMADKKVHKLEAQIEADRPKVLFANAVSASKSSCLIGELAKILKQN
                     GINIGQNKLFQWLRTNGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNV
                     TPKVTGKGQQYFINKFLNQEYLPV"
     gene            1780..1929
                     /locus_tag="TV193_001833"
     CDS             1780..1929
                     /locus_tag="TV193_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513991.1"
                     /translation="MPEDLIKQLEAGSEFLAKTCLHSKIIITVDGVRLVETKEFHPVS
                     GTLLD"
     gene            complement(1926..2126)
                     /locus_tag="TV193_001834"
     CDS             complement(1926..2126)
                     /locus_tag="TV193_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KTSC domain-containing protein"
                     /protein_id="HEL1513992.1"
                     /translation="MQRQYVSSSNVRSVGWENNTLEVEFNNGSIYHYHNVSQTEYRSV
                     LVGSVGSNIHRLAKIHTYTRIV"
     gene            2237..2521
                     /locus_tag="TV193_001835"
     CDS             2237..2521
                     /locus_tag="TV193_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1513993.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKIKVIGMLNNETEIYPLELNKKQIS
                     KMLGVDPKTFDVRFNSHKDFPRIETGGREKYPRDLVIEWYSKNWERTGIR"
     gene            2518..2664
                     /locus_tag="TV193_001836"
     CDS             2518..2664
                     /locus_tag="TV193_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1513994.1"
                     /translation="MIKKLFNFIFAKPKEESRQPYQQPRGFLDFETGKRIEIDPITRK
                     EYFV"
     gene            2868..3113
                     /locus_tag="TV193_001837"
     CDS             2868..3113
                     /locus_tag="TV193_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL1513995.1"
                     /translation="MLLTILSNSDEWRVYPEELAKRCRDSVDAVRTQLKALEKAGYIR
                     SYRKSLGGRYGTETHRFCSDTKISDEVFQELLKELNC"
BASE COUNT         1099 a          530 c          667 g          853 t
ORIGIN      
        1 tgacaaaatt ttcagaagaa ataaaaatag taaggacgaa gtcttctgtt tatgtaaaca
       61 gcgtcttaga cgttgcagat aaaaaagacc ccgcgtctgt tgcagcagtc gcagagcttt
      121 taaaggcgta taagtcgtta acagaattgt aatcaactat ggtgacttat atacgtgact
      181 tgatcgagat tgaccaaaac gatgtattga gcgtctgata gtttcagttc aataatattt
      241 ggattatcag ggcactcatt tgcaacttgg cagaatgtgt gttgcttacc atttgtgaac
      301 atgattgtaa tggtatcagt ttcattcgct agttgttcga taatatatcg tttcatacaa
      361 tcacctcctt tctgctcata ttatagcagt taaggacaac tagagaaagg acactatgca
      421 agcaaatcga attttttacg gaaaagaaaa accaacaaac gcagtagcgg gcgattgctg
      481 gtttagagat aacgaattaa tgatactcaa ggacaattgg gaagctagcg taaacaactt
      541 aaagagccct aaagttatcg gagagataga aatagaccta gagcagcatg atgtactgct
      601 gacagccaga gggagccgtc ctccactatt aatgattgat gggataatgt tgggcggagt
      661 atctaaggta ataattataa atgagttatc cgagtcttgc gcaattgtct ctcttaatga
      721 gtatatcaag gagaatttgt tcccttttga cgattttgaa tcacttcaaa ggttatttca
      781 aaagggccat cagaaattat ccgtacggga actttgctta gaaaaacgtt taggtgagca
      841 ttcttatcaa gaccatcgaa aaagctgcga tgaatagtaa aagttttctt accgctcgca
      901 agagctttct cgtaatcctg agtcagtagt ttaacagaga gatctaattg atagtcgtac
      961 acttttgttt atcctccttc cactaggata actacattat acaacagaaa ggacgctatg
     1021 aacgaactaa tcaacattac agtaaacgac aatcacgagc cagttgtcag tggtcgtgat
     1081 ttgtacaaag tgcttgaaat taaaacacaa tatacaaaat ggcttgagcg aatgagcgaa
     1141 tatggtttcg ttgaaaacga agacttcatg gctattagtc aaaaaagact aacagctcag
     1201 ggcaatcaaa ctgaatatac agaccacatt ctaaaactag atatggcaaa agaaattgcg
     1261 atgttgcaac ggaatgaaaa atctaagcaa gtccgcaagt attttattca aatcgaaaaa
     1321 gactttaaca gccccgagaa aattatggca agggcgttgc tgatggcgga caagaaagtg
     1381 cataaattag aagctcagat tgaggctgac cgacccaaag tactatttgc taatgccgta
     1441 agtgctagca aatcatcttg tctgattggt gagttagcta aaatcctgaa acagaatgga
     1501 atcaatattg gtcagaataa gctatttcag tggcttagaa cgaacggtta tctaattagc
     1561 agacgcggcg agtcatggaa tcagccaacg caaaaaagta tgcagcttgg attgtttgaa
     1621 ctcaaaaaaa cagccatcaa tcactctgac ggtcacacta caacaaatgt aaccccaaaa
     1681 gttactggta aaggccagca gtattttatt aataaattcc ttaatcagga atatctgcca
     1741 gtttagaaag gaaacaaaac caacgaaaag gagaaaagta tgccagagga tttaatcaaa
     1801 caactagaag ctggttcaga atttctagca aagacatgtt tacatagcaa gattattatc
     1861 acggtggatg gtgttcggct tgtggaaaca aaagagttcc acccagtgag cggaactcta
     1921 ctagattaga caatacgtgt ataagtgtgt atcttagcta atctatgaat atttgagcca
     1981 acagacccaa caagaacaga acggtattcc gtttggctta cattgtgata atggtaaata
     2041 gaaccattat taaactcaac ttccaaagtg ttattttccc aaccaacact tcggacgtta
     2101 ctagatgaaa cgtattgacg ttgcataact ttttctcctt tccgcgatga tagctttatt
     2161 atagcacgca aggagaatac aaaaaaagtc cgacgggaat cggactcgac aataatattt
     2221 atgaggtaat tttatcatgg atagtagatt attacaaatg cttgatgagt ttgaggcggg
     2281 tctgatagac cgtaaaatca aagtcatagg catgcttaat aacgaaacgg aaatttatcc
     2341 gctagagctt aacaaaaagc aaatcagtaa gatgctggga gttgatccta aaacatttga
     2401 cgtaagattt aatagccaca aagattttcc gcgcatcgaa acgggaggtc gggaaaaata
     2461 cccacgagat ttagttattg agtggtatag caaaaactgg gaaaggacgg ggataagatg
     2521 attaaaaaac tatttaactt tatttttgca aagccaaaag aagaatcaag gcaaccttat
     2581 caacaaccga gaggttttct ggattttgaa acaggtaaac gaattgaaat agatccgata
     2641 acaagaaagg aatacttcgt atgatgcatc aaattaatat atcgcttaga aattttgtcg
     2701 agactggaga gattgacaac atcttcgaca tttttagaat tttagatttc tactttcggg
     2761 aggtggtcag ctgatgcagt acatttttca agacgttgag agggagttac acgagcgtta
     2821 gtaatgagtt tgtcaacgat aaaaaacttt ataacaagga aaagggattg ttgttgacca
     2881 ttcttagcaa tagcgatgag tggcgagtat atccggagga attggctaaa cgttgcagag
     2941 atagtgttga cgctgtcaga actcagctaa aagcacttga gaaagctgga tacatcagaa
     3001 gttatcggaa gtcgcttggc gggcgatatg gtaccgaaac ccatagattt tgctcagaca
     3061 caaaaataag tgatgaggtt tttcaagagc tgcttaaaga attaaattgc taatgtgcaa
     3121 attgctaatg tgcaaattgc taatgtgca
//
LOCUS       DARYXS010000133         3114 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.134, whole genome shotgun sequence.
ACCESSION   DARYXS010000133 DARYXS010000000
VERSION     DARYXS010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3114
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.134"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            18..98
                     /locus_tag="TV193_001838"
     tRNA            18..98
                     /locus_tag="TV193_001838"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="TV193_001839"
     tRNA            105..175
                     /locus_tag="TV193_001839"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="TV193_001840"
     tRNA            187..259
                     /locus_tag="TV193_001840"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="TV193_001841"
     tRNA            268..339
                     /locus_tag="TV193_001841"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            358..441
                     /locus_tag="TV193_001842"
     tRNA            358..441
                     /locus_tag="TV193_001842"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Leu,seq:caa)
     gene            complement(785..1915)
                     /locus_tag="TV193_001843"
     CDS             complement(785..1915)
                     /locus_tag="TV193_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009855141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1513996.1"
                     /translation="MILRKYNDFCRLFLGRLISNCGDSIYTLVLSWYVLETTNSTWYV
                     GLLNFLIFIPNTFSFIFGKKIDSYPKKNLLVILEWAQLLAVLGIILGMSLREIHASLS
                     LTIIFSCVFLASMVGLNTYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTDYVFTAISG
                     FLLSVISYIPLLFINIVTFLGSILFFRRIAFKEIIEQTNERTDFLSGLRFIWHNKVVL
                     AITLGGAIANFLFASLNVYQLLIAREVGNSAFYGLLVSVSAIGTLVGTTFVANLVLQK
                     LSVGKAFWLATTLLGTGIGLTALVPNRFGLLLLWFLSCLFLGITHVTQKPILRTEIPD
                     EHLGEVFSAFYTVTIPTLALGSLILISLLYFSNKMLRQYDIC"
     gene            2480..>3114
                     /locus_tag="TV193_001844"
     CDS             2480..>3114
                     /locus_tag="TV193_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1513997.1"
                     /translation="MTTKEKQTKLMRRYGIFSVVVALTALAGLGAANEVKATAKKSLN
                     ELPNPVEIIQYNSTRTTDREARKYLNQLYEFLKPYLGSLEEEAQKGGPQGPVGPAGPR
                     GERGEPGPKGDRGPEGQRGEQGPAGPIGPQGPRGDKGETGEIGPRGEQGPTGPTGKPG
                     ERGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKG"
BASE COUNT         1003 a          578 c          692 g          841 t
ORIGIN      
        1 gtaatttaat atgttttgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctgaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttcag
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttagttttat acttaaagcc
      361 ggcgtggcgg aattggcaga cgcgctggac tcaaaatcca gtgtccgcaa ggacgtgccg
      421 gttcgacccc ggccgccggt atagtttaaa aatattgaaa aaacaaggtt tgtaaacctt
      481 gtttttttgt tttatgactt gatgtcagag gatcagattg gtcctctcta gatgttaaag
      541 gtaatgagaa tcttggcttc aaagctccta aatccaaagc attgcgcttg atgtctttga
      601 tcacctgtta gtggcgtgca gcttagcgtt tgaatttgga ataaggttgc tccaaggcat
      661 gtgtgatgtg agctttggat actaggactt ttagccaatt ctttgtgggt gagctttttc
      721 tttacgtttg gttttgatta atgtcgcaat atcagttatc atgtgttctc tggttaatga
      781 cgctttagca aatatcgtat tgtcttagca tcttgtttga gaaataaagc agactaatta
      841 agataagcga acccaaggca agtgttggga tggttacggt ataaaaagca ctgaaaactt
      901 caccaagatg ctcatcagga atctcagttc gtaaaatagg tttttgggta acatgcgtta
      961 ttccgagaaa tagacaggaa agaaaccaaa gaagcaacaa accaaaacgg ttggggacta
     1021 atgctgtaag gccaataccg gtgcccaaaa gggtagttgc tagccaaaaa gcttttccta
     1081 cacttaactt ttgcaagaca aggttagcaa caaaggttgt tcctaccagg gttccgatag
     1141 cacttacaga tactaagagg ccataaaaag ctgaattccc tacctctctt gctattaata
     1201 actgatagac atttaagctg gcaaaaagga aattagcgat agcacctccc aatgtgatgg
     1261 ctaacaccac tttattgtgc cagataaagc gcaagccact taaaaagtct gttcgttcat
     1321 ttgtttgttc aattatttct ttaaatgcta ttcttctaaa aaataggatt gaacctaaga
     1381 aggtaacgat attaatgaaa agcaaaggaa tgtagctgat cacagaaagc aaaaagccac
     1441 tgatggcagt aaaaacataa tctgttccat tataagccac tgacatatac atttctgctt
     1501 tagctagatc tttagtagga atgagtttag gtacaagagc atcttgaaca gtataggtat
     1561 tcaacccaac catagaagcc agaaaaacac aactaaaaat aatggttaag ctaagacttg
     1621 cgtgtatctc tcttaaggac attcctaaaa taatacctaa gacagccaat aattgggccc
     1681 actccagaat cactagcagg ttcttcttag ggtacgaatc aatctttttt ccaaagataa
     1741 aggagaaggt gtttggaata aaaatgagaa agttcaataa tccaacatac caagtactat
     1801 tagtggtttc tagtacatac caggacagca ctagggtata aatcgagtca ccgcaattgc
     1861 taatcagtcg ccccagaaat aaccggcaaa aatcattata tttccttaat atcatattgt
     1921 atcctttgat aaagagttta aacatctttt atattatagt atcagatgat aaaaaatcac
     1981 tgaatgatag ctgtgtttga tgtttgcaac attttaaaat atctttgcaa aaatcatacc
     2041 tagacacata caatcccaca taagttttaa aagcattcaa ttgcctttta agatctttat
     2101 gagtcatgtt tgtaaagata tcctcttgca acagatctct taatctctaa ttgtatccaa
     2161 taagaagcag ctttgtcaat acggaagccg aatagtcttt ttgcctttcc ttgtcagctg
     2221 ggcaatcatg agggctttgt gctttgatct tttgcatcta taaaagggtg aatctattga
     2281 tgaggtgtta tcggtagtgg ggcctactga tgtcaataac tgacgtcaga taattacctc
     2341 tttaattaga aaaaaaaaaa aacgaaacta cggagagaac ctaataactg gctatttctt
     2401 gatataagcc agcgtgttaa aatcttcttt gggagaaaat ttagaaaaaa ataatatttc
     2461 tatcactaag gagagaaaga tgacaactaa agaaaaacaa acaaaactaa tgcgcaggta
     2521 tggcattttc tcggtagtcg ttgccctaac agctctagca ggtctaggag cagctaatga
     2581 agttaaggca actgctaaaa aatctttaaa tgagttacct aatccagtag aaattattca
     2641 atataattca acaagaacta ctgatagaga agctagaaag tatcttaatc aattatatga
     2701 gtttttgaaa ccttatttag gaagtttaga agaagaagct caaaaaggag ggccacaagg
     2761 acctgtggga cctgctggtc ctagaggtga acgcggagaa ccaggaccta aaggagaccg
     2821 aggtcctgag ggccaaagag gtgagcaagg cccagcgggg cctattggac cccaagggcc
     2881 tcgtggtgac aagggtgaaa ctggagaaat tggacctagg ggagaacaag gtccgaccgg
     2941 tcctactggt aagccaggag agcgtggccc taagggtgac agaggcgaac gcggcgaaaa
     3001 aggcgagcaa ggccagcgtg gcgaaaaggg cgagcaaggc caacgtggcg aaaaaggtga
     3061 acaaggccaa cgcggtgaaa agggcgagca aggccaacgt ggcgaaaaag gtga
//
LOCUS       DARYXS010000134         3089 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.135, whole genome shotgun sequence.
ACCESSION   DARYXS010000134 DARYXS010000000
VERSION     DARYXS010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3089
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.135"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..1243
                     /locus_tag="TV193_001845"
     CDS             <1..1243
                     /locus_tag="TV193_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1513998.1"
                     /translation="TADKEKAETEAKKAKEEAKTAKEAAHQEQEKAKQLEQANQQANQ
                     RANLAEKSKKDLETQKEKLEQEIKEATEAKNKAEQKLKDLQDSASQGSELSKQLLKEK
                     EELTTKLQELQKQAEEKTTEIEKLKQELEANKQNSGQLGQQEQKLQEQLNKVQKELKQ
                     KEMELKQAQEQLKQEQKPHEGGGDSDASKARITELEKQVQTLTKEKADLSSTLESTKA
                     QLSETQARLSEAQKQLTAAQEKLTTLEAEKTALQHQVETISKQLSETRDLSEKEKAAL
                     QEQINKLKAEIEQKTKEIEALKQGMQSHQGQEKPKDPKTPETPKDPKTPEKNDQPQAP
                     EKRSVPWTALTPAKPIDTTKAPKSSAPSPQTGAATPKKQLPATGDTATPSFFTAAAMA
                     VLASVGVLNLSPRRKKNQNNR"
     gene            1660..2502
                     /locus_tag="TV193_001846"
     CDS             1660..2502
                     /locus_tag="TV193_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEL1513999.1"
                     /translation="MVSVLSRVIKGIIIALGFILPGVSGGVLAAILGIYERIIAFLAH
                     IREHFVENVLFFLPVGVGGILGIALFSYPVDYLLKHYQVPVLWGFAGAIIGTVPSLIK
                     TSTKTSQRDQVDWLWLVLTFVLSGLGLYFLNDLVGTIPASFTAFVLAGALIALGILVP
                     GLSPSNLLLILGLYSPMLIGFKSLDLVGTFLPIAIGGLLTMLAFSKIMDFALKHYHSR
                     VYHFIIGIVLSSTLLILIPNSSNKEAISYAGAGLGTWLMALLLFGLGVWLGLWMSQLE
                     EKYK"
     gene            complement(2605..>3089)
                     /locus_tag="TV193_001847"
     CDS             complement(2605..>3089)
                     /locus_tag="TV193_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL1514000.1"
                     /translation="FKPGEVSFPSGRVEEGETYQQAAIRETVEELNIEPEQVHVWGEI
                     DYLVQPTRSIHCFVAELAIDDWRRLRVNEEVDSLFTVPLEELMAQAPVAYPLQMQSII
                     SSDFPLDRIPNGEQYRLRYMQDQVLLYEHLEKPIWGITAQLTNRFIEIVTEARQHDDI
                     "
BASE COUNT         1040 a          696 c          585 g          768 t
ORIGIN      
        1 tacggctgat aaagaaaagg cagagactga agctaaaaaa gcgaaagaag aagctaagac
       61 cgctaaagaa gctgctcatc aagaacaaga aaaagctaaa caattagaac aagctaatca
      121 acaggctaac caaagagcta atctggcaga aaaatctaaa aaagatttag aaactcaaaa
      181 agaaaaactt gaacaagaga ttaaagaagc tacagaagct aaaaacaaag ccgagcaaaa
      241 attaaaagac ctacaagatt cagctagtca aggcagtgaa ttgtctaaac agctgttaaa
      301 agaaaaagaa gaattaacaa caaaacttca agagcttcaa aaacaagctg aggaaaaaac
      361 aactgaaatt gaaaagctaa aacaagagct tgaagctaat aaacaaaaca gtggtcagct
      421 aggtcaacag gaacaaaagc ttcaagagca attgaataag gttcaaaaag agctgaaaca
      481 aaaggaaatg gagttaaaac aagctcaaga acagctgaaa caagaacaaa aacctcacga
      541 aggtggcgga gattctgacg cttccaaagc aagaatcact gagctagaaa aacaagttca
      601 aacactaacc aaggaaaagg cagatctgtc atcaaccctt gagtcaacaa aagctcaatt
      661 gtcagagact caagcaagac tatcagaagc tcaaaaacaa ttgactgctg ctcaagaaaa
      721 gttaacaaca cttgaagccg agaaaacagc gcttcaacat caagttgaga ccatttcaaa
      781 acagctatca gaaacacgtg accttagcga aaaggaaaaa gcagcactcc aagagcaaat
      841 caataagcta aaggctgaga ttgagcaaaa gaccaaggaa attgaagcct taaagcaagg
      901 catgcaatca catcaaggtc aagaaaaacc aaaggatcca aaaactccgg aaacaccaaa
      961 ggatccaaag actcctgaga aaaacgatca gccacaagcg cctgaaaaac gtagtgtccc
     1021 ttggactgct cttacaccag ctaagccaat tgacactacc aaagctccta agagctcagc
     1081 accaagccca cagactgggg cagcaacacc taaaaaacaa ttaccagcaa ctggtgatac
     1141 agcgacacct agcttcttta ccgctgctgc tatggcagta ttggctagcg tcggtgtcct
     1201 aaatctctca cctagacgca aaaagaatca aaacaaccgt taatgtagag actctcatat
     1261 ctggattgaa taacagcaaa cccgacatga gcaaaaacaa atgtctaacc aaaaatcact
     1321 gacattagta ctttaaccaa agcctttgag tcaagctaaa caggctgtcc tgcctattgg
     1381 cttgactcgt tttgtgattg tgaaacacac caaggtcaaa cctaccttgt cctccatttt
     1441 aaacctactc ttttctccca tacccacttt agcttacgca agaaggtgcc taatcatcac
     1501 ttttggtagc ttcgatgctc tatataaatg gatcaacaaa gataaatcat acaaaactgc
     1561 gagttgttcc tatagtcacg atagctctta cagatatgaa aagtaaatac agctattaaa
     1621 aatatggtac aataggggta cgatttttag gaggcatgta tggtttcagt tctttcacga
     1681 gtgattaagg gaataattat tgcgcttggc tttattttac cgggagtatc tggaggagta
     1741 ttagccgcta tccttgggat ctatgagcgt atcattgcct ttttagctca tatacgtgag
     1801 cattttgttg agaatgttct ctttttcctg cctgttgggg ttggtggtat tttagggatt
     1861 gccctctttt cttaccctgt tgactatctg ctcaagcact atcaggtacc agtcttatgg
     1921 ggcttcgctg gggccatcat aggaaccgta cctagcctga taaagacttc gacaaaaaca
     1981 tctcagcgtg accaagttga ttggctctgg ctagtattaa cctttgtcct atcaggactg
     2041 ggactttatt tcttaaatga tctcgttggg acaatacctg caagctttac cgcctttgtc
     2101 ctagctggtg ccttgattgc tttaggtatt ttggtacctg gtcttagccc gtctaatctt
     2161 ttattaattt taggacttta ctcacccatg ctgattggct ttaaatcact tgatttggta
     2221 ggaacctttt tacccattgc tattggtggc ttattaacca tgctagcttt ttccaagatt
     2281 atggattttg ctctcaagca ctaccattca cgcgtttacc actttattat cggtatcgtc
     2341 ctatccagca ccctgcttat tttaattcca aatagcagta ataaggaagc tatctcttac
     2401 gccggtgcag gtcttggcac ctggctaatg gctctgctat tatttggcct tggtgtctgg
     2461 cttggtctat ggatgagcca gcttgaggag aaatacaaat aacactcgat acaccagcaa
     2521 gtacctctaa cagcagcatt aagatcaaaa aaacgaatga ctagctctca gccttatcac
     2581 cagctgtgac tagcattcgt ttttttatat gtcatcatgc tgtcttgcct ctgtcacgat
     2641 ttctataaaa cggttcgtca attgagcagt tataccccag ataggctttt ctaaatgctc
     2701 atagagtaat acctgatctt gcatgtacct caacctgtac tgctctccat tagggatacg
     2761 atccaacgga aagtctgacg agattatcga ttgcatttgt aaaggataag caacaggagc
     2821 ttgcgccatg agctcctcca aaggcaccgt aaacaagcta tcaacctctt cattgaccct
     2881 aagccttctc caatcatcaa tagccagttc cgcaacaaag caatgaatgc tacgagtcgg
     2941 ctgaactaaa tagtcaatct ccccccaaac atgaacctgc tcaggctcta tattgagctc
     3001 ctctaccgtc tcacgaatag ccgcctgctg ataagtctca ccctcctcca cgcgcccact
     3061 aggaaaagaa acctcccctg gcttgaatg
//
LOCUS       DARYXS010000135         3078 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.136, whole genome shotgun sequence.
ACCESSION   DARYXS010000135 DARYXS010000000
VERSION     DARYXS010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3078
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.136"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            59..778
                     /locus_tag="TV193_001848"
     CDS             59..778
                     /locus_tag="TV193_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1514001.1"
                     /translation="MPRFSKAFQYMGATTMLGLSLLAANVNANTNADTVTVDLTYTAY
                     SNLTNEQKAGIQKGTPNEVPIQDKLHYVLVYDKSCGVTASPKGMMSTPKANAKVLPKT
                     GGAADGLVGLAVGLGLLSVSGYLIYKNRKSGSYVLIALLVAGGATTAVSAVDVVRHLN
                     DIVTKTTVKGVSFTYTPEEKVDDYCYVGYIVTQENSPAPTPEPKPDPVPTPEPKPEPK
                     LDPVPTPEPTPDPEYFEAIPQ"
     gene            complement(890..3076)
                     /locus_tag="TV193_001849"
     CDS             complement(890..3076)
                     /locus_tag="TV193_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1514002.1"
                     /translation="MKNFKTFITSFINTRLGFVLTLLFCFWIKTLWAYHADFSLDLGN
                     AYQVFLTIINPIPLALLLLGFTLYIKNTRAFYISSWIVYIILNLLLISNSIYYREFSD
                     FITVSAMLASSKVSAGLGDSALNLLRIWDIVYVLDFIILISLSVTKTIKKDPRPFNKR
                     ASFAVTALSCLLLSVNLFLAEIDRPELLTRGFSNTYIVRALGLPAFTIYSGNQTYQAQ
                     KERNGATAEELVDVKQYVKNHYAAPDPQYFGIGKGKNVIVIHLESFQQFLIDYKLKDD
                     DKDYEVTPFINSLYHSNATLAFSNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYG
                     GENTQFATPSILAQNGGYTSAVFHGNVGTFWNRNNAYKQWGYHYFFDSSYFSKQTDKN
                     SFQYGLNDKYMFRDSIKYLEQLQQPFYTKFITVSNHYPYTSLRGESSEEGFPLAKTDD
                     ETINGYFATANYLDSALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNVSLAELLGK
                     DPETWSEYDNAMLQRVPYMIHIPGYTNGGIKETFGGEIDSLPTLLHILGIDTSKMVQL
                     GQDLLSPQNSQMVAQRTSGTYITPDYTSYSGRLYNTQTGLEITNPDEMTMAKVKEIRA
                     AVAQQLAASDAIQTGDLLRFDTDNGLKPVDPTTFIYTKQLKQLKEISEKLGSHSTSIY
                     SKNGNKSTQKLFKAPSYLELNPKEAEKPESTSSSDPKEESVKEQSQ"
BASE COUNT          907 a          571 c          682 g          918 t
ORIGIN      
        1 ggagatgcct ttttagttat tggttttatt ctacaaaaca ttaaggagaa tagttataat
       61 gccacgtttt tctaaagcgt ttcaatacat gggagctaca acgatgttag gtctatcttt
      121 gctagcagct aatgtcaatg ccaacactaa tgctgatacg gtaacggtag atttgaccta
      181 tacagcctat tctaatctga caaatgaaca aaaagcaggc attcaaaaag gcactccaaa
      241 tgaagtacct atccaagata aattgcatta cgttcttgtt tacgacaaaa gctgtggagt
      301 gacagcatct ccaaaaggaa tgatgtctac ccctaaggct aacgctaagg tcttgcctaa
      361 aacgggtggt gcagcagatg gtctggttgg tttggcagta gggctaggct tactaagtgt
      421 ttcaggctat cttatttaca aaaataggaa aagcggtagc tatgtgttga ttgccttgtt
      481 ggtagctggt ggtgcgacaa cagctgttag tgcagttgat gtggtacgtc atctcaatga
      541 tatcgtcact aagactacgg ttaagggggt aagctttact tacactccag aagaaaaggt
      601 tgatgattac tgttatgtgg gttatattgt gacgcaagaa aatagcccag caccgacacc
      661 cgaacctaag ccagatcctg tgccaacacc agaaccgaag cctgagccta agctagatcc
      721 tgtgccaaca cctgaaccga caccagatcc agaatacttt gaggccattc ctcaataaaa
      781 gtgtcagaac taaaaagccc tcattaagtt gtaacgctca atgaaggctt ttagcttgct
      841 tttagtcttc tacgagagcg atcctagtga ggcttgcttt agacatccac tactgacttt
      901 gttccttaac ggattcttct ttagggtcag aagacgaagt agattcaggt ttttcggctt
      961 ctttaggatt taactccaga taagaaggtg ctttaaagag cttttgagtt gatttgttgc
     1021 catttttact ataaatgctg gttgaatgtg atcctaattt ctctgatatc tctttgagtt
     1081 gttttagctg cttggtataa atgaaggttg ttgggtcaac aggtttcaga ccattatcgg
     1141 tatcaaagcg tagtaggtct cctgtttgga tagcgtcact agctgctagc tgctgagcaa
     1201 cggctgctcg tatttctttg accttagcca ttgtcatctc atcagggttt gtaatttcca
     1261 agcctgtttg agtgttgtaa aggcgaccgc tatagctagt gtagtctggc gtgatataag
     1321 ttccagaggt tctttgtgct accatttgac tattttgtgg cgacaagaga tcctgtccta
     1381 gttgaaccat cttgctggta tcaatgccca agatatgcag taaggttggt aaggaatcaa
     1441 tttctccgcc aaaggtttct ttgatcccgc cattggtata gcctggaata tggatcatat
     1501 atggtacacg ctggagcatt gcattgtcat attcggacca agtttcaggg tctttaccta
     1561 gtaattctgc caagctgaca tttctggaat tagaaatacc atagtggtca ccatatagaa
     1621 caaagataga attgtcataa agtcctgtcg ccttgagata atcaaaaaat gatttcaagg
     1681 ctgaatccag atagttagct gtagcaaagt aaccattgat ggtttcatca tcggttttgg
     1741 ctagtggaaa gccctcttca ctgctttcgc ctctaaggct ggtgtaaggg tagtggttgc
     1801 tgacggtaat aaacttagtg tagaagggtt gttgaagctg ttcaaggtac ttgatagaat
     1861 ctctaaacat gtatttgtca tttaggccat actggaaaga gtttttatca gtctgttttg
     1921 aaaaatagct tgaatcaaaa aagtaatgat agccccattg cttataagca ttattgcgat
     1981 tccagaaggt tcctacattc ccatgaaaga cggcactagt atagccgcca ttttgtgcta
     2041 ggattgatgg tgtggcgaat tgtgtgtttt cgccgccata atttaccata aaagaaccac
     2101 tgtttaagcc aaataatgaa ttttccatca tggtctctgc atcagacgtt tttccagcct
     2161 tgacctgatg gaaaaagtta gagaaggcta gtgtggcatt ggagtggtag agggaattaa
     2221 taaaaggtgt gacctcatag tccttgtcgt catccttgag cttgtaatca ataagaaatt
     2281 gttggaagct ttccaagtgg atcacaatga cattttttcc cttaccgatt ccaaaatatt
     2341 gaggatcagg tgcggcgtag tggttcttga catattgctt aacatcgact aattcttcag
     2401 cggttgctcc gttacgctct ttttgtgctt gataggtctg gtttccgctg taaatggtaa
     2461 aagcaggcaa tccaagcgct ctaacgatat aggtatttga aaatcctcta gtcagaagct
     2521 ccgggcggtc aatctctgca agaaacagat taacagataa gagcaagcaa gacagtgctg
     2581 taacagcaaa ggaagcccgc ttgttaaaag gacgcgggtc ttttttgatg gtcttagtta
     2641 ctgataaact aatcagaatg atgaaatcaa ggacgtaaac aatatcccaa atgcgcaaaa
     2701 ggtttaaagc agagtctcct aaaccagcag aaaccttact actggctagc atagcactaa
     2761 ccgtaatgaa atctgaaaac tctcggtaat aaatagaatt tgatattaac aagaggttaa
     2821 ggataatata gacgatccaa gagctgatat aaaaggccct agtattcttg atataaaggg
     2881 taaatcccaa tagtaacaaa gctagaggga ttgggttaat aattgttaga aagacctgat
     2941 aggcatttcc caaatctagt gaaaagtcag catggtaagc ccatagggtt tttatccaaa
     3001 agcagaagag aagcgttagc acaaagccta atcttgtatt gataaagctt gtgataaatg
     3061 ttttaaaatt cttcacag
//
LOCUS       DARYXS010000136         3054 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.137, whole genome shotgun sequence.
ACCESSION   DARYXS010000136 DARYXS010000000
VERSION     DARYXS010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3054
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.137"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..159
                     /locus_tag="TV193_001850"
     CDS             <1..159
                     /locus_tag="TV193_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514003.1"
                     /translation="WYKSKQVDLNAAEVQNLALEMAYRDVVDSNNASLVLDWSENPDV
                     IFDGNGGS"
     gene            159..1262
                     /locus_tag="TV193_001851"
     CDS             159..1262
                     /locus_tag="TV193_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_115223326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1514004.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGPQGPPGKTGEQGPPGPAGKPGTTDYNQLQNKPNLDAFAQKKE
                     TDSKITKLASSKADKSAVYLKAESKIELDKKLSLTGGVMTGQLRLKPNSGIKHSSSVG
                     GAINIDMSKSTGAAMVMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGKTNAVNIVM
                     RQPSAPNFSSALNITSANEGGSAMQIRGIEKALGTLKITHENPSLGADYDENAAALSI
                     DIVKKANGAGTAAQGIYINSTSGTTGKLLRIRNENKDKFYVNPDGGFWSCANSTVAGN
                     LTVNDPTSEKHAATKKYVDEKIAELKKLIQKTD"
     gene            1272..>3054
                     /locus_tag="TV193_001852"
     CDS             1272..>3054
                     /locus_tag="TV193_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1514005.1"
                     /translation="MSRDPTLTLDESKLVIGPDGRMHYTFTASQDNQKVRLASNCLGT
                     TRFNQVMIERGDKATDYVAPVVVEGSGESTGVFKSLEEMLSGLQSINLELTDTKNSNL
                     WSKIKLTTNGMLREYHRDHIKTEIVESADGIAKRIADDTGQKLALINETIKGIKREYQ
                     DADRQLSASYQAGIDGLKTQLANDKIGLQAEIKLSAQGLSQKYDDELRKLYAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLRSVQQSTAKQISQEIRDRTGAV
                     SRVQQDLASYQRRLQDAEKNYSSLTQTVKGLQSTVSDPSGKIQSRFTQLQNQIDQRVT
                     RDDVMSIINLSGDSIKLAIQKAGGIDAKMSGSEIISAINLNTYGAVIAGKHIALDGNT
                     TVNGTFTTKIAEAIKIKADQIIAGTLDASKARIINLNASSIVGLDANFIRAKIEHTIT
                     SLLEGKVIRARNGAMMIDLSNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSNAT
                     PKNYTGSALYASIGITSSGDGINSASSGRFCGARFFRYARGYEHTALVDQAEIYGDDI
                     VFSDDFNIDRGFKMRPSLMPKMVDLNKM"
BASE COUNT         1005 a          612 c          709 g          728 t
ORIGIN      
        1 tggtataaat ctaagcaagt tgacttaaat gcggcagagg tccaaaattt ggctctggag
       61 atggcttata gagacgtagt tgatagcaat aatgctagtt tagttttgga ttggtcagaa
      121 aatccagatg ttatttttga tggaaatgga ggtagttaat gtcagagact atatcagcta
      181 tagttgtgca taaaagcatg acaaaaaacg agtgggagtc tagtgacatc attttgccac
      241 aaggccagct cgtctatgag tctgacacag gccatagtaa atttggcgac ggtaaaaata
      301 gatatgcaga tttgatctat caaggtgggc caccaggtcc ccaaggccca ccaggtaaaa
      361 caggggagca gggcccgcca ggccctgctg gcaagcctgg aacgacagat tataatcaac
      421 tccaaaataa accaaatcta gatgcgtttg cacaaaaaaa agaaactgat agtaaaatca
      481 ccaaattagc atcaagcaaa gcagataaaa gcgctgttta cttaaaagca gagtcaaaaa
      541 tagagctaga caaaaaattg agtttgacag gtggcgttat gacaggccaa ctacggctta
      601 aacctaatag tggtattaag cactcatctt ccgtaggagg agcgattaac attgatatgt
      661 ctaaatcaac aggtgctgct atggtgatgt atacaaataa agatactact gatggaccat
      721 tgatgatttt acgctctgac aaagatacgt ttgatcagtc agctcaattt gtggattaca
      781 gcggtaagac taatgctgta aatattgtaa tgcgccagcc aagcgcacct aatttttcct
      841 cggcacttaa tataaccagt gccaacgaag gcggtagtgc gatgcaaatt agaggcatcg
      901 aaaaagcatt gggaacgctc aaaattactc atgagaaccc aagtcttgga gcggattatg
      961 atgaaaacgc tgcagcgtta tctattgata ttgtcaaaaa ggcaaacggt gcaggaacag
     1021 ccgctcaggg aatctacatt aactcaacct caggcacaac agggaagttg cttagaatta
     1081 gaaacgaaaa taaagacaaa ttttatgtaa atccagatgg tggcttttgg tcatgtgcaa
     1141 attcgactgt agctggtaat ctaacagtta acgatccaac atctgaaaaa catgctgcga
     1201 ctaaaaaata cgtagacgaa aaaattgctg agttaaaaaa acttatacaa aaaacagatt
     1261 aaggaggata aatgagtaga gatccaacac taacattaga cgagtcaaaa ctcgtcatag
     1321 gaccagacgg ccgcatgcat tacacgttta cggctagtca agacaatcaa aaagtcagat
     1381 tagccagcaa ctgtctagga acaactcgct ttaatcaggt tatgattgag agaggcgaca
     1441 aagcgactga ctatgttgcg cctgttgtcg ttgagggcag cggtgagtcg acaggtgtgt
     1501 ttaaaagtct tgaggagatg cttagtggtc tacagtctat taatttagag ctgacagata
     1561 ccaaaaactc caatctttgg tcaaaaatca agctcacgac aaacggtatg ttacgcgagt
     1621 atcatcgtga tcatattaaa acagagattg ttgagagcgc agatggtatt gccaagcgga
     1681 ttgccgatga cactggccaa aagctggcac taatcaatga gaccatcaaa ggtatcaagc
     1741 gtgagtacca agacgcagat agacagctat ccgcgagcta ccaagcgggc attgatggcc
     1801 taaaaactca actggccaat gacaaaatcg gtctacaagc tgagattaag ctgtcagctc
     1861 aaggcttgtc gcaaaagtac gacgatgagc tgcgcaagct gtatgctaag attaccacca
     1921 cctcatcagg cacgaccgaa gcgtacgaaa acaagcttga gggcttgcgt gctgagttta
     1981 cccgtagcaa ccaaggcatg cgcactgagt tagagtcgca gattagcggg ttaaggtctg
     2041 tgcagcagtc aactgcaaaa caaatctcgc aggagattag agacaggaca ggtgctgtta
     2101 gtcgtgtgca acaggactta gccagctatc aaagacgctt gcaggacgcc gaaaaaaatt
     2161 acagcagttt aacccagacg gttaaaggtc tacaatcaac tgttagcgat ccgtcaggta
     2221 aaatccagtc gaggtttaca caactacaaa atcaaatcga ccaacgtgtg acaagagatg
     2281 acgttatgtc aatcatcaac ctatccggag atagtatcaa actagctatc caaaaggctg
     2341 gtgggattga tgctaaaatg tctggcagcg agattatctc agcgattaat ctcaatacgt
     2401 atggcgcagt cattgcaggt aaacacatcg ctcttgatgg caatacaacg gtcaatggca
     2461 cttttaccac taagatagcc gaggctatca aaatcaaggc tgatcagatt atcgcaggta
     2521 ctttagatgc ctcaaaggct cgtatcatta atctaaacgc tagcagcatt gtcggcttag
     2581 atgctaattt tatcagggcc aaaatcgagc atacgatcac aagtttgctc gagggcaaag
     2641 ttatcagagc tcgcaacgga gcgatgatga ttgacttgtc aaactctaag attgacttta
     2701 acagcaacgc taccattaac tttaataaca aagacaacgc tttggtacgt aaagacggta
     2761 cccacacagc ctttgtgcat tttagcaatg ccacgccaaa aaattataca ggtagtgcgc
     2821 tttacgcctc gatcgggata acatcgtcag gtgacgggat taacagcgcg tcgagcggtc
     2881 gtttttgcgg tgctaggttt tttaggtatg cgcgaggtta cgagcacaca gcgcttgtcg
     2941 atcaggccga aatttacggt gatgatattg tctttagcga cgattttaac atcgatcgtg
     3001 gctttaagat gcggcctagc ctaatgccaa aaatggtcga tctcaataag atgt
//
LOCUS       DARYXS010000137         3012 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.138, whole genome shotgun sequence.
ACCESSION   DARYXS010000137 DARYXS010000000
VERSION     DARYXS010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3012
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.138"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..199
                     /locus_tag="TV193_001853"
     CDS             <1..199
                     /locus_tag="TV193_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009530021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1514006.1"
                     /translation="EEQEEMENIEVLKEYRSIDISIDDFLEMMRRYKKEEKQEKMKLQ
                     EMRNTENHNNMEENHENQMEE"
     gene            204..1640
                     /locus_tag="TV193_001854"
     CDS             204..1640
                     /locus_tag="TV193_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1514007.1"
                     /translation="MAITLSGVIFLILALLGTMLFNHQIVFAQGSLIPTLISPTEVLA
                     QTKVEVKIKYIFKDESVYKEEIIEVETGQVLDSGDLPMLEDNMKFIDEFLFYKVKGDG
                     TDEIIRKVEKITVKDKEIQTEEEKPKQDESTETEDKKTEDKGTQTELSKDDISKMEKE
                     AKELQDKLDKLNGEIRDKDKLSDKQKEKIKDLEAEIESLKEKMKKDKGNKDLSEDMKK
                     EIDKLTEKVKELEKKPTETNKAPVTSQSVTPISPISGIKTSSGISSQTPQSSGKGSSD
                     AVSSGNTTKDTGKTESKEKEKEVRYPNKLTPKAPANNSSQDSSMDGASSNVNTNKGVA
                     SAPSKARGTVTENKDNANNDYPIHHGDSSDNKEADKYSADARQFITFQTKSGKTFHLI
                     INHDEQSENVMLLTEVSEDDLLNMVEKKENPQEEIKKMEETVPESEVKKEEPKKEEGK
                     GSGSYIFLGIIVLAVVGAGYYFKIYKKK"
     gene            1893..2486
                     /locus_tag="TV193_001855"
     CDS             1893..2486
                     /locus_tag="TV193_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005956659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEL1514008.1"
                     /translation="MNYENKIEKYLKQSGGIITTAYCKENNIPTIYLSRLLKDGRLSK
                     VRKGIYITKDGDYDEYYFFQHQYKKAIFSYETALYLLGQTDKIPWSIDVTVYNGYKFN
                     EKPNGFNVHYVKKSIYDLGVTQKPTMFGNKVKVYSYERTLCDFIAHKEEMDIEVYVKL
                     IQSYSSYKERDIHSLYDIAMKMGIENKVREVMEVAYE"
     gene            2479..>3012
                     /locus_tag="TV193_001856"
     CDS             2479..>3012
                     /locus_tag="TV193_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL1514009.1"
                     /translation="MNKAKLTALCHKVSKEVGLSFNAVMLYYFLESILKKLAGSKYSE
                     RFIFKGGFLLSSVVGIDSRSTVDIDFLLRNMQLSEENIVQMLNETLKPEEFDDIFYEL
                     QNIVPIKEEDQYGGFRANILCKMENIRQIVPLDIATGDVITPHPIDYKYVSSFGEEEI
                     IIKAYPIETMLAEKIQTI"
BASE COUNT         1246 a          372 c          627 g          767 t
ORIGIN      
        1 agaagaacag gaagagatgg aaaatattga ggttttaaag gaataccgaa gtattgacat
       61 ttctattgac gattttttag aaatgatgag acgttataaa aaagaggaaa aacaagaaaa
      121 aatgaagtta caggaaatga gaaatacaga aaatcataat aatatggagg aaaatcatga
      181 aaatcaaatg gaagaataaa aaaatggcga taacattgtc cggagtaatc tttttgatac
      241 ttgctttact tggaacaatg cttttcaatc accagattgt ttttgcacaa ggtagtttaa
      301 tcccgacact gattagtccc acagaagttt tagctcaaac taaagtggag gttaagataa
      361 aatatatatt taaggatgag agtgtatata aggaagaaat aattgaagta gaaaccgggc
      421 aagttcttga cagtggggac ctaccaatgt tagaggataa tatgaaattt attgacgaat
      481 ttttgttcta taaagtaaag ggagacggta cagatgagat tatccgtaaa gtagaaaaaa
      541 ttacagttaa ggataaagaa attcagacag aagaggaaaa gccaaaacag gacgaaagca
      601 ctgagacgga agataaaaaa acagaagata agggaacaca gacagagctt tctaaagatg
      661 atatttccaa aatggaaaaa gaggcaaaag agcttcagga taaacttgat aaattaaatg
      721 gtgaaatcag ggataaagac aaactaagcg ataaacagaa agaaaaaatc aaagaccttg
      781 aagctgagat tgaaagtctg aaagaaaaaa tgaagaaaga taagggaaat aaagacttat
      841 cagaagatat gaaaaaggaa atagataagc tgacggaaaa ggtgaaagag cttgagaaaa
      901 agccaactga aacaaacaaa gctcctgtaa catcacagtc tgttacaccg attagtccta
      961 tttcagggat taagacaagc tcaggtattt cttctcaaac accacagagt tccggtaaag
     1021 gttcatctga tgcagtaagc tccggcaata ctacaaaaga tacaggtaaa actgaatcaa
     1081 aggagaaaga aaaggaagtt cgctatccca ataagctgac accgaaagct cctgctaata
     1141 acagtagtca ggattcatca atggacggtg caagtagcaa tgtaaatacc aataagggtg
     1201 tggcttcagc tccgtcaaag gcaagaggaa ctgttacaga aaataaagat aatgcgaata
     1261 atgattatcc aattcatcat ggggatagca gcgataacaa agaagcagat aagtattcag
     1321 cagatgcaag acaatttatt actttccaga caaaatccgg aaagacattt catttaatca
     1381 tcaatcacga tgagcaaagt gaaaatgtaa tgcttttgac tgaagtatct gaagatgatc
     1441 ttctgaatat ggtagagaag aaggaaaacc cgcaagaaga aatcaaaaaa atggaagaaa
     1501 cggtaccgga aagcgaagta aaaaaagaag agccgaaaaa ggaagaaggt aaaggtagcg
     1561 gctcatatat ttttttagga atcatcgttc ttgcagtagt tggagcagga tattacttta
     1621 aaatctacaa gaaaaagtag gaagatgatg attatgatga agatgaggaa gaatatgatg
     1681 aatttgaaga tgagtatgaa aaagaggacg atacagaaga tttggaagaa acagtagaag
     1741 aacagcataa catagatgat atggcaatcg actcttatga tgaagaagat gaggaataaa
     1801 gttataaaaa gagaaatgta aaccctgatg ttgcgtttac acttaaaaaa tggtataatg
     1861 caagtgtaaa cgcaacaaag ggggtggatg ggatgaatta tgaaaataaa attgaaaaat
     1921 atttgaagca atcaggtgga attattacaa cagcatactg taaggaaaat aatataccga
     1981 cgatatatct cagtcgacta ttgaaagatg ggagattgtc aaaagtaaga aaaggaattt
     2041 atataacgaa agatggggat tacgatgagt attatttctt tcaacatcag tataaaaagg
     2101 cgatattttc ttatgaaaca gcactttacc tgcttggaca aacagataaa attccttgga
     2161 gtatcgatgt aaccgtttat aacggatata aatttaatga aaaaccgaac ggtttcaatg
     2221 ttcattatgt aaaaaaatca atttatgact taggggtaac ccaaaaacct acaatgtttg
     2281 gaaataaagt taaggtatat tcatatgaga ggacactctg tgattttatt gctcataaag
     2341 aagaaatgga tatagaggtt tatgtaaaac ttattcaatc atattcctct tataaagaaa
     2401 gagatatcca ttccctctat gacattgcaa tgaaaatggg aattgaaaat aaagtaagag
     2461 aggttatgga ggtggcttat gaataaagct aaattaacgg ctctttgcca taaagttagt
     2521 aaagaagtcg gtctttcgtt taatgctgtt atgttatatt attttttaga aagtatttta
     2581 aaaaaattag caggaagcaa atatagtgaa cgatttattt ttaagggcgg ctttttgtta
     2641 tcaagtgtag ttggaattga ttcaagaagt actgtagata tagactttct tttgagaaat
     2701 atgcaactat cagaagaaaa tattgttcaa atgctgaacg aaactttaaa accggaagaa
     2761 ttcgacgata ttttttatga attgcaaaac attgtgccaa tcaaagaaga agatcaatat
     2821 ggaggatttc gtgcaaatat cttatgtaaa atggaaaata taagacagat tgtaccactt
     2881 gacattgcaa caggagatgt tattacacct catccgatag attataagta tgtgagttct
     2941 tttggagaag aagaaataat aatcaaggct tatccgatag aaactatgct tgcagaaaaa
     3001 atacaaacta tt
//
LOCUS       DARYXS010000138         2839 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.139, whole genome shotgun sequence.
ACCESSION   DARYXS010000138 DARYXS010000000
VERSION     DARYXS010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2839
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.139"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            15..698
                     /locus_tag="TV193_001857"
     CDS             15..698
                     /locus_tag="TV193_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1514010.1"
                     /translation="MYKILVVDDDYEILKLMRTILEMKNYKVTTYQEVTFPINFRDFQ
                     GFDLILLDVMMPNVEGTQICQLIRDKVASPIIFVSAKDTEDDIIKGLNLGGDDYLPKP
                     FSVNQLIAKVSAHLKREERVKHGENVEKITRELLPITFYLQEKMLCVSGKPVPLTSRE
                     YHILELLSSHPNKVFTREDIYEHVYDDEANALFRSISEYVYQIRIKFAPFNLNPIKTV
                     RGVGYKWYD"
     gene            691..2043
                     /locus_tag="TV193_001858"
     CDS             691..2043
                     /locus_tag="TV193_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1514011.1"
                     /translation="MTKTYSIRYRVGITVGEILIGIAILVISLLIIPYLLVFTKQLNI
                     HGTSFDIVLGDKVSTEEITKQMDTLTFDYVLFNRKNGEVLNGNYQKTELSYYETVFED
                     KKPINVGTIDYKAYSNDQILLVVRQPTLPEFVNPSLRKVSFNTLSIILFIVGTLSIVF
                     ISVTKLLREFAHDFRLIQKISLNMGSRDYKIERSTTKISEFNDILAMLYQKDDELTIL
                     LEAERAEKKDLSFQVAALSHDIRTPLTVLKGNLELLEMTDLSNQQISFIGSINHSVSV
                     FEKYFNSMITYSRLLIEERDYQEVIEVTEFMSGLQIEIQEIMHTEQVDFDMKNNLRIT
                     HFKGNRFNLERALINILVNAAQHATDVKQVSLTAKEEQDQLIFEIWNSGSKFSKQALN
                     GANKLFFTEDNGRSSKHYGIGLSFAQGVAVRHQGKLQLLNPLKGAQVNLIIRKYELLL
                     "
     gene            2527..>2839
                     /locus_tag="TV193_001859"
     CDS             2527..>2839
                     /locus_tag="TV193_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1514012.1"
                     /translation="MDVKIQDIRKSYKDRDILKGVSFEIQKGTICGLLGINGAGKSTL
                     MKIIFGLEKADSGNVIFYNQKDQHVNYEIGALIESPAIYMNLSAFDNLKTRALLYNIS
                     GE"
BASE COUNT          952 a          411 c          535 g          941 t
ORIGIN      
        1 tatgaggtaa gactatgtat aagattctag ttgttgatga tgattatgag attttaaaac
       61 ttatgcggac cattcttgag atgaaaaatt acaaggtaac aacctatcaa gaagtgactt
      121 ttccaatcaa ttttagagat tttcaagggt ttgacttgat tttattagat gtcatgatgc
      181 ctaatgttga aggtacacaa atttgtcaat taatccgaga taaagttgct tctcctatta
      241 tctttgttag tgctaaagat actgaagacg atattattaa aggattaaac cttggtggag
      301 atgattacct cccgaagcct tttagtgtga atcagcttat agctaaggtg agtgctcatc
      361 tgaaacgtga agagcgagta aagcatgggg aaaatgtcga aaagataaca agagaattat
      421 taccaatcac cttttattta caagaaaaaa tgctttgtgt tagtggaaaa ccagtaccat
      481 taacgagtcg agagtatcat attttagagt tgctttcaag tcatcctaac aaggtattca
      541 ctcgtgaaga tatctatgag catgtctatg atgatgaagc aaatgctcta tttcgctcta
      601 tttcagagta tgtttatcag attcgtataa aatttgctcc ttttaacttg aatcctatta
      661 agacagttcg tggagtgggg tataagtggt atgactaaaa catactcaat aaggtataga
      721 gtaggaataa cagttggcga gattttaata gggatagcaa ttttagttat atctcttctt
      781 atcattccct atttgttagt gtttactaaa cagttaaata ttcatgggac aagttttgat
      841 atcgttttag gtgataaggt ttcaacagaa gaaatcacta aacagatgga tacacttacg
      901 tttgattacg tcctttttaa tcgaaagaat ggtgaagttc ttaatgggaa ctatcaaaaa
      961 acggaattaa gttattacga gacagttttt gaggataaaa agccaattaa tgtgggtaca
     1021 attgactata aagcttatag taatgaccaa atattattgg ttgtgagaca accaacactc
     1081 ccagagtttg ttaatccctc ccttcgaaaa gtttccttta ataccttatc tattatcctg
     1141 tttatcgtag ggacactatc tattgtattt atctctgtca caaagctatt gagagagttt
     1201 gctcatgatt tccgtttaat tcaaaaaatt tctttaaata tggggagtcg tgattataaa
     1261 attgaacgct caacaacaaa aataagtgaa tttaatgata tattagctat gctctatcaa
     1321 aaggatgatg aactgacgat attgttagaa gctgaaagag ctgaaaagaa ggatctctct
     1381 tttcaagtag cggctctttc acacgatata aggacacctt taacggtttt aaaaggaaat
     1441 ttagaattac ttgaaatgac agatctttct aatcaacaga taagctttat tggttctatt
     1501 aatcatagtg tttcagtatt cgagaaatat tttaattcaa tgataaccta ttctcgcttg
     1561 ttaatagaag agagagatta tcaggaagtt atagaggtaa cagaatttat gagcggtttg
     1621 cagattgaaa ttcaggaaat tatgcatact gaacaggttg attttgacat gaagaacaat
     1681 cttagaatca ctcattttaa aggtaatcga ttcaatttag aaagagctct cattaatatt
     1741 ttagttaatg ctgcacagca tgctactgat gtgaagcaag ttagcttaac tgcaaaagaa
     1801 gaacaagatc agctaatttt tgaaatctgg aatagtggtt cgaagttttc aaaacaagca
     1861 ttaaatggtg ctaataaatt attctttact gaggataatg gtagaagcag caagcattat
     1921 gggattggtt tatcttttgc tcaaggtgtc gctgtaaggc atcagggtaa gttacaatta
     1981 ttaaatccac tcaagggtgc ccaggttaat ttaatcatta gaaagtatga gctcctcctg
     2041 taaagtagat agttaaatca tgaccacccg ttagatgagc tgtacttcca ttcgttagag
     2101 tttctgtcta actttttgga gattgcttca aaaacaagtg ccttggcttc tgtaggttga
     2161 tctcctcagc cgagcctaaa gacaatcact gaacagtgtt tacttgatta tcgcccgttc
     2221 aacgggcttt tttcatattc tgaactcgct ggccttcata ttcttaaata ctcaagaatc
     2281 aactgaatat tattttactg acattatagc ttttagtcat aatgaaggtt atgcaacgtt
     2341 tgtagcccaa ataagtcttt aaccggacaa agataggttc catattcacg ttgtaagaac
     2401 atttggttgc ttgcttctat aaaaatgttt gattttcttt ttattccaaa tcttgatgct
     2461 ttcattattt tctgaacaaa tattgaaaaa gaaaccgtat gattaaataa aaaaggaggt
     2521 gtaatcatgg atgtaaaaat tcaggatatt aggaaatctt ataaagatag agacatttta
     2581 aaaggagttt catttgagat acagaaaggc actatatgtg gactgcttgg tatcaacggt
     2641 gctgggaaat caacgctaat gaaaattatt ttcggtttag aaaaagcgga tagtggaaat
     2701 gtgatttttt ataaccaaaa ggatcagcat gtgaactatg agatcggtgc attaattgaa
     2761 tctccagcga tatatatgaa tttgtcagct tttgataact taaaaaccag agcactctta
     2821 tataacattt ctggtgaaa
//
LOCUS       DARYXS010000139         2761 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.140, whole genome shotgun sequence.
ACCESSION   DARYXS010000139 DARYXS010000000
VERSION     DARYXS010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2761
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.140"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..484
                     /gene="glmU"
                     /locus_tag="TV193_001860"
     CDS             <1..484
                     /gene="glmU"
                     /locus_tag="TV193_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="forms a homotrimer; catalyzes the acetylation of
                     glucosamine-1-phosphate and uridylation of
                     N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc;
                     function in cell wall synthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEL1514013.1"
                     /translation="SRLGEGVVVSQSVIEDSVLADGVTVGPYAHIRPDSQLDESVHIG
                     NFVEVKGSHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKYQTVIGDHAFI
                     GSHSTLIAPVEVGENALTAAGSTIAQSVPADSVAIGRSRQVVKEGYAKRLPHHPNQAK
                     "
     gene            515..1069
                     /locus_tag="TV193_001861"
     CDS             515..1069
                     /locus_tag="TV193_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1514014.1"
                     /translation="MDFEEKTIKRQEIFDGHIFKVAVDDVQLPNGLGQAKRELIFHRG
                     AVAILAVTPERKLLIVKQYRKAIEAISYEIPAGKLEVGEANSALEAAARELEEETAYS
                     GDLRLIHEFYTAIGFCNEKIKLYLATDLQRVANPRPQDADEVIELLELSYQECMDLVA
                     QGKLVDAKTIIALQYYALHFGGDV"
     gene            1069..1317
                     /locus_tag="TV193_001862"
     CDS             1069..1317
                     /locus_tag="TV193_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514015.1"
                     /translation="MGKPLLTDDIIEKAQRGEQFEPDDYADFETKIMTFEDKHTDRIY
                     KSRRIENAKRSRFQSRLNLILLAVLVLIALLVYAVFNL"
     gene            1341..2042
                     /locus_tag="TV193_001863"
     CDS             1341..2042
                     /locus_tag="TV193_001863"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEL1514016.1"
                     /translation="MKIGIIAAMEEELRFLLEQLHDSQEHQVLSNTYYTGRLGRHELV
                     LVQSGVGKVMSAMTVAMLAEHFQADAIINTGSAGAIASGLAIGDVVVADRLVYHDVDV
                     TAFGYDYGQMAAQPLYFDSDSKLVETFKQVLDQEKTNSRIGLIATGDSFIAGQDSIDT
                     IKAHFPETLAVEMEGAAVAQAAQAAGKPFIVVRAMSDTAAHDANMTFDQFIVEAGKKS
                     AKVLIAFLEALPDKK"
     gene            complement(2098..2745)
                     /locus_tag="TV193_001864"
     CDS             complement(2098..2745)
                     /locus_tag="TV193_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL1514017.1"
                     /translation="MTPNKEDYLKCIYEIGEQNIKISNKMVAERMKVSAPAVSEMIKK
                     MIAQGWIVKDKTCGYYLTEQGQRLVANLYRKHRLMEVFLIHQLGYTAREVHQEAEVLE
                     HTVSDMFIDRLDKTLGYPTFCPHGGTIPRRQQPLIEINKTTLNTIKELGIFRLSRVHD
                     HFELIQYLEAHQLTINSEFRLIQIDDFAKTYTITYADKELIIPENIAKQLFVTAI"
BASE COUNT          758 a          539 c          695 g          769 t
ORIGIN      
        1 ttcgaggctt ggtgagggcg tagtggtgag ccagtcagtg attgaggatt cagtcctagc
       61 agatggtgtg acagtagggc cctatgcgca cattcgccca gactcccagc tcgatgagag
      121 cgttcatatt gggaactttg tagaggttaa ggggtctcat ctaggggcca ataccaaggc
      181 agggcatttg acttacctgg ggaatgccga gattggctca gaggttaata ttggtgcagg
      241 aagcattacg gttaattatg atggtcaacg gaaataccag acagtgattg gcgatcacgc
      301 ttttattggg agtcattcga ctttgatagc tccagtagag gttggggaga atgctttaac
      361 agccgcaggg tctacgatag cccagtcagt gccggcagac agtgtggcta tagggcgcag
      421 ccgtcaggtg gtgaaggagg gctatgccaa gaggctgcca catcacccaa atcaagcaaa
      481 gtaaaatgat ggagagaaag caaggagatc agacatggat tttgaagaaa aaacgattaa
      541 aaggcaagag atttttgatg gtcacatttt caaagttgcg gtagatgatg tccaattgcc
      601 aaacggccta ggtcaggcta agcgcgaatt gatttttcat cgcggtgcag tcgctatatt
      661 ggctgtaacg ccagagcgta agctgttaat tgtcaagcag taccgtaagg ctatcgaagc
      721 gatttcttat gaaattcctg ctggaaaact agaggtcggt gaggccaact cagcattaga
      781 agcagcagca cgagagctgg aggaagaaac cgcctattct ggtgatttgc gtcttattca
      841 cgagttttat acagcgattg gtttttgtaa tgaaaaaatt aagctgtact tggcgacaga
      901 cctgcagaga gttgccaatc ctagaccaca ggacgcagat gaggtgattg agcttcttga
      961 gctgagctat caagaatgta tggatctagt ggcacaagga aagcttgtcg atgctaaaac
     1021 catcattgcc ctgcaatatt acgcccttca ttttggaggt gatgtgtaat gggcaagccc
     1081 ttgctgactg atgacattat cgaaaaggct cagcgcggag aacagtttga gcctgacgat
     1141 tatgcagatt ttgaaaccaa aatcatgacc tttgaggata agcatactga tcgtatttac
     1201 aaaagtcgca gaattgaaaa tgcaaagcgc agtcgctttc aatcgcggtt aaatctgatt
     1261 ctcttagcgg tgcttgtctt gattgctctc ttggtttatg cggtctttaa tttatagaaa
     1321 aaaacaaata aggatatcat atgaaaattg gaattattgc ggctatggaa gaggagctgc
     1381 ggtttttatt ggagcagctc cacgatagtc aagagcatca ggtgctttcc aatacctact
     1441 atacaggtcg tcttggtcgc catgagctcg tcttagtcca atctggtgtt ggaaaggtca
     1501 tgtcagcgat gacagttgcg atgctagcag agcattttca ggctgacgct attataaata
     1561 caggatcggc tggagcaata gctagtggct tggctattgg tgatgttgtt gttgctgatc
     1621 gcttggtgta tcatgatgtg gacgtgacgg cctttggcta tgactatggt caaatggctg
     1681 cgcagcccct ttactttgac agtgatagca agctggttga gacctttaag caggtgcttg
     1741 atcaggaaaa gaccaatagt cggattggcc tgattgcaac aggagatagc tttattgccg
     1801 gccaagacag tattgatacc attaaagcac atttcccaga gaccttagca gtggaaatgg
     1861 agggagcagc agtggcacag gcagctcaag ctgctggcaa gccatttatt gttgttaggg
     1921 cgatgagtga cacagcggcc cacgatgcta atatgacctt cgatcagttt attgttgagg
     1981 ctggaaaaaa atcagccaag gtcttgatag cctttttaga ggccttacct gataaaaaat
     2041 gatgaccaaa aaaacctgat agcctgtggt gacagcaaat atcaggtctt tttttattta
     2101 aatagcagta acaaagagct gcttggcgat gttttcagga atgatcaatt ccttatctgc
     2161 ataagtgatg gtataggttt ttgcgaagtc atctatttga atcagtctaa actcactatt
     2221 gatcgtcagc tggtgtgctt ctaggtactg gataagctca aagtgatcat gcaccctgct
     2281 caaacgaaaa attcccagct ctttaatagt attaagcgtt gttttgttga tttcgattag
     2341 tggctgctgg cggcgtggaa ttgtccctcc atgagggcaa aaagtaggat agccaagggt
     2401 tttatccaag cgatcaataa acatatctga cacagtatgc tctagtacct cagcctcttg
     2461 gtgcacctct ctagcagtat agcccagttg atggatcaag aaaacctcca tcaatcggtg
     2521 cttacgataa agatttgcca ctaagcgctg cccttgctct gttagataat agccgcaggt
     2581 cttatccttt acaatccagc cttgtgcgat cattttctta atcatttctg acacagcggg
     2641 tgcagaaacc ttcattctct ctgcaaccat tttgttagaa attttaatgt tttgctctcc
     2701 gatttcataa atacatttca aatagtcttc tttattaggc gtcatgtcta aaagcctttc
     2761 t
//
LOCUS       DARYXS010000140         2730 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.141, whole genome shotgun sequence.
ACCESSION   DARYXS010000140 DARYXS010000000
VERSION     DARYXS010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2730
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.141"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..525
                     /locus_tag="TV193_001865"
     CDS             <1..525
                     /locus_tag="TV193_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1514018.1"
                     /translation="KDREKLDFYATDKRAIHELLKREQFLSPIYEPACGMGHIGKVLE
                     EYGYKVKATDICYRGYGEEREVDFFTVTENILDIVTNPPYFCASEFLRHALEISGPKV
                     KIAMLFRLAFLEGQSRYELFRKYPPKRVYVFSKRLNCAKNGEFEKYKSSAIAFAWFIW
                     EVGYKGITELRWIR"
     gene            567..1313
                     /locus_tag="TV193_001866"
     CDS             567..1313
                     /locus_tag="TV193_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1514019.1"
                     /translation="MDKNEVLQSQENQTKEVMQEIKEEYTKTADFLEEHINQQLVIAK
                     EMKEEMQNKDFDVNIKELKALKEEITGLKAEIKRLNEMENITFGSLIIRDIKSVGNTL
                     INLQEKAVGSIKHLYDNMKHQLSYNLTKAQEKFVQMKIGIVKGLVNSMQDFIKDQQKK
                     LDSCLAKLDNLSKEIQKDEEKLEKGNLNKEKTLIKKREQSIEEKESQKEKMEKKPSVL
                     KKLKENQQKIKQEEKNKDIKALKKDKGMEL"
     gene            1330..>2730
                     /locus_tag="TV193_001867"
     CDS             1330..>2730
                     /locus_tag="TV193_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1514020.1"
                     /translation="MNDLIKNYENIPDEMKKEKRWCLYKIIQRDGKNTKLPLMPNKEP
                     AKSNDKATWNSYEDCIMALKHNVGEGLGFFLGDGYIGIDIDKVSDDIMEYNTNHHVSS
                     MTADFLREVSTYAEISPSKTGLHFIGKGEVPGERKRYKNLEIYDKDRFFTVTGNVIKD
                     RDRSKIESIDSELKPLYEKYMPKTNKISAENKRSPTVTSYNGDQDILEKLFDRGYFSY
                     AGEDLRQIYYGNYERYFNSQSEADFFMLQRLLYYTGNVEMAISFMESSGLKREKWYKR
                     RGNTDYIHYIADKAISSINQFYDWEKVYTSKEKIEEKRYENKKKKEGDTVPRYEFDEV
                     KQILDFAKEEFKENIDRYETYLKVMGNNYKYPYFNQLSIYTVNENATACAEYDYWKSI
                     GRNVNRGEKGIPVLDIEREKIKYIFDASQTVSLNHNISEVKLWEYSNNKHVAALDTLI
                     DVFKEKNSNLIFSTEDK"
BASE COUNT         1150 a          316 c          567 g          697 t
ORIGIN      
        1 aaagacagag aaaaattgga tttttatgcc acagataaaa gggcaattca tgaactttta
       61 aaaagagagc agtttctatc tcctatttat gagccggctt gtggaatggg gcatatcgga
      121 aaagttctgg aagaatacgg ttataaggta aaagctacag atatttgtta taggggatat
      181 ggagaagaaa gagaagttga tttttttaca gtaacagaaa atatattgga tatagtaacc
      241 aatccaccat atttttgtgc aagtgagttt ttaaggcacg ctcttgaaat atcaggacct
      301 aaagtaaaga tagcaatgct atttcggttg gcttttttgg aaggtcaatc aagatatgaa
      361 ttatttagga aatatcctcc aaagagagta tatgtatttt ccaaaaggct taattgtgca
      421 aaaaacggag aatttgagaa atacaaaagc agtgctattg cctttgcctg gtttatatgg
      481 gaggtgggat acaaaggtat tacggagtta aggtggatta gataaaagga tggaataaaa
      541 caactgaaaa aacgaaggag gatagtatgg ataagaatga agtattacaa tcacaggaaa
      601 atcagacaaa ggaagttatg caggagatta aagaggaata taccaaaaca gctgactttt
      661 tagaagaaca tataaatcag cagcttgtga ttgctaagga aatgaaagaa gagatgcaaa
      721 ataaggactt tgatgtaaat atcaaagaat tgaaagcact caaagaagaa atcaccggat
      781 taaaagctga aattaaacga ttaaacgaaa tggaaaatat aacttttggt tcattgatta
      841 taagagatat caaatctgta ggaaataccc ttatcaattt acaggaaaaa gcggtaggaa
      901 gtattaaaca tctgtatgat aatatgaaac atcagctttc ctataacctt accaaagcac
      961 aggaaaaatt tgtacagatg aaaataggaa ttgtaaaagg attggtaaat tccatgcagg
     1021 attttatcaa ggatcaacaa aagaaactgg atagttgctt agcaaaactt gataatctat
     1081 ctaaagaaat tcaaaaagat gaagaaaaac tggaaaaagg caatctgaat aaagagaaaa
     1141 ccctgataaa aaaaagggaa caaagcatag aggaaaaaga aagtcaaaag gaaaagatgg
     1201 agaaaaaacc gtctgtgcta aaaaaattaa aggaaaatca gcaaaaaatc aagcaggaag
     1261 aaaagaataa agatataaag gcacttaaaa aagataaggg aatggaacta taaaaaagag
     1321 gtggtagtta tgaatgacct cataaaaaac tatgaaaata ttcctgatga gatgaaaaaa
     1381 gagaagcgtt ggtgcctata taaaatcatt caaagagacg ggaagaacac gaaacttcca
     1441 ctaatgccaa ataaagagcc ggcaaaatca aatgataaag ctacatggaa tagctatgag
     1501 gattgtatca tggcattaaa acataatgtt ggcgaagggc ttggcttttt cttaggagat
     1561 ggatacattg gaatagatat tgataaagta agtgatgaca ttatggagta caatacgaat
     1621 catcatgtaa gctctatgac ggctgatttt ttaagagaag tttccaccta tgctgagatt
     1681 tctccatcga aaacaggact acattttatt ggaaaaggag aggtgccggg agaaagaaaa
     1741 agatataaaa atcttgaaat ttatgataag gataggtttt ttacagttac cggtaatgtt
     1801 ataaaggata gagataggag caaaatagaa agtattgaca gtgagctaaa gcccttatat
     1861 gaaaaatata tgccaaagac aaataaaatt agtgctgaaa ataaaagaag tccaacggtt
     1921 acttcttaca atggggatca ggacatatta gaaaagttat ttgacagggg atatttttca
     1981 tatgcaggag aagatttaag acaaatttac tatggtaatt atgaacgcta ttttaacagc
     2041 caatcggagg ctgatttttt tatgctacaa aggctgcttt actatacagg aaatgtagaa
     2101 atggcaatat catttatgga aagtagcgga ctgaaaagag aaaaatggta taaaagacga
     2161 ggcaataccg attatatcca ctatattgca gataaggcga taagctctat caatcaattt
     2221 tatgattggg aaaaagtata tacatcaaag gaaaaaatag aagaaaaaag atatgaaaat
     2281 aagaagaaaa aggagggaga tacagtgcca agatatgaat ttgatgaagt caaacagatt
     2341 cttgattttg caaaagaaga atttaaagaa aatatagaca ggtatgaaac ttatctcaaa
     2401 gtgatgggaa ataactataa atatccgtac tttaaccagc ttagcatata tacggtaaat
     2461 gaaaatgcaa ctgcttgtgc agaatatgac tattggaaaa gtataggaag aaatgtaaat
     2521 agaggagaaa aaggaatacc tgttttagac attgaaagag agaagataaa gtatatcttt
     2581 gatgcaagtc agacagtaag tttaaatcac aacatttctg aagtaaagtt atgggaatat
     2641 agcaataata agcatgtagc tgccttagat actcttatcg atgttttcaa agaaaaaaac
     2701 agtaacctta tattttctac tgaagataag
//
LOCUS       DARYXS010000141         2680 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.142, whole genome shotgun sequence.
ACCESSION   DARYXS010000141 DARYXS010000000
VERSION     DARYXS010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2680
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.142"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            22..1461
                     /locus_tag="TV193_001868"
     CDS             22..1461
                     /locus_tag="TV193_001868"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEL1514021.1"
                     /translation="MDLPRSIRYRPYQEWSKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKCEQVLIDKPDD
                     VTEHFRDPQLFTYQDQLYAIIGAQNLQQQGIIKLYKANNNDVTSWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRRKLLGGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDIDYPTDKYAYQGALSLVKELRLKNG
                     RLHQAPVPALSKLRDKAQPFQNKKNSSNCYELALTIEAQQATELLLFADTQHKGLKLT
                     VDTCKGQLTIDRSKAGAQYAQEFGAKRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEGQSGIELLKGQVSGYYYEMRY"
     gene            1466..2431
                     /locus_tag="TV193_001869"
     CDS             1466..2431
                     /locus_tag="TV193_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1514022.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKQGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPHIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKGADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDNLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEVLLKKIGNEKTSKDYVLPITLLPGGSL"
BASE COUNT          811 a          652 c          555 g          662 t
ORIGIN      
        1 caatacctaa ggagacctga catggattta ccaagatcta ttcgctaccg accatatcaa
       61 gaatggagca aggaagccta tcaagcaatc caacaaaagg tggcccagtc tttatggcgc
      121 agccatttcc atatagaagc tcgtacaggt ctcctcaatg acccaaatgg cttttcttat
      181 tttgctggca gctttcagct tttctatcaa aattggccct ttggagcagc tcatggtcta
      241 aagcaatggg tacacaccac atcaactgac ttggtgcatt ttacagaaac caaaactcgg
      301 ttgctgccgg atcatcaaaa cgatagtcat ggcgcttatt ccggctctgc ttatcctatt
      361 ggtgacaaac tctttttatg ctatacagga aatgtccgca gcaaggattg ggtacgccac
      421 ccactacaaa taggtgcctg gatggaccaa tcaggccaca tcacaaaatg tgagcaggtg
      481 ctcattgaca agccagatga tgtcacagag cattttcgtg acccccagct ctttacctac
      541 caagatcagc tttatgccat cattggtgca cagaatttgc aacaacaagg tatcattaag
      601 ctctacaagg ctaacaacaa tgatgtcacc agctggcaat ttgttgctga cttggatttt
      661 gatgactcag gcaccgcata catgattgaa tgccctaatt tggttttcat tgaagataag
      721 cctgtgctta tcttctgccc tcaggggctt gccaaatcag agcttgatta ccaaaacatt
      781 tatcccaata cctataaggt atttcagacc tttgatccta aaagacgcaa gctccttggg
      841 ggaggtccaa tccaaaacct tgattttgga tttgaagctt atgcgacaca ggcctttaat
      901 agccctgatg gtagggtact ggcagtttct tggattggcc tgccggacat cgactaccca
      961 accgataaat atgcctacca gggagcgctt agtctagtca aggaattacg actcaaaaat
     1021 ggaaggctac accaagcacc agtccctgct ctcagtaagc tacgagacaa agcccagccc
     1081 tttcagaaca aaaaaaacag ctcaaactgc tatgagctgg ctttgaccat tgaagcacag
     1141 caagcaacag agcttttgct ctttgccgat acacagcaca aggggctgaa actgaccgtt
     1201 gacacctgca aaggacagct aacaattgat cgcagcaagg caggcgccca gtatgcccag
     1261 gaatttggag caaagcggtc ttgccaaatt cctgtcaatc gtgctacact taatatctac
     1321 gtagacaagt ctattctaga gatttttgtc aaccaaggcg aagcagtcct cacgagtcgt
     1381 gtctttccaa atgaggggca gtctggcatt gagctgctaa agggccaggt gagtggctac
     1441 tattatgaaa tgaggtacta gacaagtggt cgcaaaatta acagatgttg cagcattagc
     1501 tggtgttagc ccaacaacag tctcacgtgt gattaacaaa aaaggctatc tgtcccagaa
     1561 aaccattgat aaggtgaaca aagccatgcg agagcttggc tacaagccaa ataacctcgc
     1621 acgaagcctg cagggcaaat cccctcagct cattgggctg atctttccta acattagtaa
     1681 tattttttac gcggaattga ttgagcattt agaaatcgag ctctttaagc aaggttataa
     1741 agccatcatt tgcaacagtg aaaacaaccc gatcaaagaa cgagattatt tagaaatgct
     1801 agctgccaat caggttgacg gcattatctc atcaagccat aacctaggta ttgatgatta
     1861 tgagcgtgtc gaggcaccca tcgtcgcctt tgatagaaac ctcgctcctc atatccccat
     1921 catatcctct gataattttg aaggagggaa attggccgca aaaaccctgc aaaagcatgg
     1981 ctgccaaaaa atgatcatga ttacaggaaa tgatcattct gactccccaa caggtcttag
     2041 acagctaggc tttaattacc agctcaaaaa aggcgctgat attataaaac tgccaaatga
     2101 tctttccagt attcgccgcg aaatggaaat caagtctatt ttggcgacaa gaaggcctga
     2161 cggcattttt gcttctgatg atttgacagc tatcctcatc atgaaggttg ctggccagct
     2221 tggcatagca attccagata acctgaagct tatcggctat gacggtacgg cttttattga
     2281 gcattatttc ccacagctca ccaccatcaa gcagccgatc aaggagattg ccagcttaac
     2341 cgtagaagta ttactgaaaa aaataggtaa cgaaaaaacc agcaaggact atgtcttacc
     2401 gatcaccctg cttcccggag gcagtctcta agagcaatag ctcttcttct gtgattagcg
     2461 gctttcccct agcttctccc ttacttgggg cactaaagta aaaaccaaag cacgaggtgg
     2521 gaaaccctag accaccagga tacacccaga taggtcccca aaagaaagct tgataagcct
     2581 gaccacctaa caaaacctgc acacaaggaa agcttcctca agctgtcctt tgtacccttt
     2641 tcctaacaat gccaccaaaa acacatgtaa cagcaagtga
//
LOCUS       DARYXS010000142         2599 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.143, whole genome shotgun sequence.
ACCESSION   DARYXS010000142 DARYXS010000000
VERSION     DARYXS010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2599
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.143"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..1529
                     /locus_tag="TV193_001870"
     CDS             <1..1529
                     /locus_tag="TV193_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1514023.1"
                     /translation="HVTLGEFVANCAETYKDKTAIVDGELNLSYDELDKLSNKYANGL
                     LKAGFKKGDKIVLQLPNCYEFIVISFAMFKTGIIPIMSLPAHRKNELKGIIEKSEAVA
                     YISKDKYLGFSYVDMVRDMKSELNTNLEIYILGESEEYKNFSSLIENDCFYKYPDVDY
                     RSIGLLLLSGGTTGIPKLIPRRHCDYIYVAKKTTDRCNVNQESVYLASLPIAHNFPLG
                     CPGIMGTFAKGGKVVLCNVTSPDEILPLIEEEKVTITGFVPAIANICMDYLEYEEYDL
                     SSLEVIQVGGSVLEPWLAEKIEKVFDVKLQQIFGIAEGLILTTNEEDNDKIRWQTQGK
                     PISEHDEILIVDEQGKIVGIEEYGELIVRGPYTIYGYYNLPEVNETCITQDCYFKTGD
                     KARKLKDGNYQIVGRIKEIINRAGEKITPLELEEILLTHENINSVQVVGLPDRLQGES
                     IAVFILNGDKELTLEEVRKFLISNNVADFKLPDTVKYIDAWPLTALGKIDRNKLKETF
                     "
     gene            1544..>2599
                     /locus_tag="TV193_001871"
     CDS             1544..>2599
                     /locus_tag="TV193_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="HEL1514024.1"
                     /translation="MELNNIKERAKELVKDWLKSIFVEKVVSENENLIEKGLSSIQVM
                     QLSGKLKKTGIKISFAKLMEEPNLSKWYELIDKSRVKSDKNIESSIIQSDESKFDLTD
                     VQYSYLIGREDDQILGGVGCHAYLEIDGENIDEDKLKEAWNKLQYRHPMLRTKFTKDG
                     KQEILYKPYSEEIEVFDLSDLDEETLHLKLVEIREQKSHRKLNVNQGQVAGVALAKFS
                     DEKSRIFFDVDLLVSDVMSMSIMIKELAELYSGVELDNLNEYTFKDYMQNGIGESIND
                     ADKEFWEQKINSFEIERPNLPLRKQPEQIKETKFTRRKRIIKKSEWETIKDIAASYRS
                     TPSMVLLTAYALVLERWC"
BASE COUNT          973 a          305 c          557 g          764 t
ORIGIN      
        1 aacatgtgac cttgggagag tttgttgcga actgtgcgga aacgtataaa gataaaacag
       61 cgattgtaga tggagaatta aacttatctt atgatgagct tgataaactt tcgaataagt
      121 atgctaatgg actacttaaa gcaggtttta aaaaaggaga taagattgta ttacagcttc
      181 caaattgtta tgaatttata gtgatatctt ttgcaatgtt taaaacagga attattccga
      241 ttatgagttt gcctgcacat cgaaagaatg aattaaaggg tattatagaa aagtctgagg
      301 cggtagcata tatttcaaag gataaatatt taggtttttc atatgtggat atggttcggg
      361 atatgaaatc tgaattaaat acgaacttgg agatttatat tcttggagaa agtgaagaat
      421 ataaaaattt ttcgtcactt attgagaatg attgtttcta taaatatccg gatgtcgatt
      481 acaggagcat aggattattg ttattatctg gcggtacaac aggaataccg aaactgattc
      541 caagaagaca ttgcgattat atctatgttg caaagaaaac gacggaccgg tgtaacgtaa
      601 atcaggaaag tgtatatctt gcttctttgc caatagctca taattttcct ttggggtgtc
      661 cagggataat gggtactttt gcaaaaggcg gaaaggtggt tttgtgcaat gtgacaagcc
      721 ctgatgaaat tttaccttta attgaggaag aaaaggttac gataacagga tttgttcctg
      781 caattgccaa tatttgtatg gattatttag agtatgaaga gtatgatctt tcctctttgg
      841 aggttataca agtcggaggt tcagttttgg aaccttggtt ggcagaaaaa attgaaaaag
      901 tttttgatgt taaactacaa cagattttcg gaatcgctga aggattgatc ttgacaacaa
      961 atgaagaaga taacgataaa ataagatggc aaacacaagg caaaccaatc agtgaacatg
     1021 atgaaatact gattgtggat gaacaaggaa aaattgtagg gattgaagaa tatggagaac
     1081 ttatcgttag aggtccttat accatttatg gttattataa tcttcctgaa gtaaatgaaa
     1141 catgtataac acaagattgt tattttaaga ctggtgataa agcacgaaaa ctaaaagatg
     1201 gtaattatca aattgtcgga aggatcaaag aaatcatcaa tagagcaggt gaaaagataa
     1261 caccacttga attagaagaa attttgctta ctcatgaaaa tatcaactcg gtacaagttg
     1321 tagggctgcc agatcgtctg caaggagaat ccattgctgt atttatttta aatggagata
     1381 aggagcttac actggaagaa gttagaaaat tcttgatttc taataatgtg gcggatttta
     1441 aattgccgga tactgttaaa tatattgatg cgtggccatt aacagcttta gggaaaatag
     1501 atagaaataa attaaaagaa actttttaaa ggaggatttt ggaatggaac ttaacaatat
     1561 aaaagaaaga gctaaagaat tagtaaagga ttggttgaaa agtatatttg tagagaaagt
     1621 agtttcagaa aatgaaaatt taattgaaaa aggtttaagt tccattcaag tcatgcaact
     1681 gtctggaaaa ttaaagaaaa cggggataaa aatttcgttt gcaaaactta tggaagaacc
     1741 gaatttgtcc aagtggtatg aacttattga taaatccaga gtgaaaagtg ataagaatat
     1801 agagtcatca attatccaaa gtgatgaaag taagtttgat ttaacagatg tccagtactc
     1861 ctatttaatc ggaagagaag atgatcagat tttaggtggc gtgggttgcc atgcatatct
     1921 tgaaatagat ggagaaaata ttgatgagga taagttaaaa gaggcttgga ataagcttca
     1981 atacagacat cccatgctta gaacaaaatt tacgaaagac gggaagcagg aaatattata
     2041 caaaccgtac agtgaagaaa tagaagtttt tgatttatct gatcttgatg aagaaacgct
     2101 gcatctaaaa ttagtagaaa ttagagaaca aaaatctcat aggaaattaa atgtaaatca
     2161 aggtcaggtt gcaggagtag cactagcaaa attttcagat gagaagtcaa ggatattttt
     2221 tgacgtagat ttgcttgtat ccgatgtaat gagcatgagt attatgatta aagaattagc
     2281 tgaactttat tcaggagtag aacttgataa tttgaatgag tatacgttta aggattatat
     2341 gcaaaacgga attggcgaat caatcaatga tgcagataag gagttttggg aacaaaaaat
     2401 aaattccttt gaaatagaaa gaccgaattt accattaagg aaacagccgg aacaaattaa
     2461 agaaacgaag tttacaagaa gaaagagaat tattaaaaaa agtgaatggg aaaccataaa
     2521 agatatagca gcatcgtatc gaagtacacc atctatggtt cttctaactg cctatgctct
     2581 tgttcttgaa agatggtgt
//
LOCUS       DARYXS010000143         2476 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.144, whole genome shotgun sequence.
ACCESSION   DARYXS010000143 DARYXS010000000
VERSION     DARYXS010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2476
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.144"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            68..682
                     /locus_tag="TV193_001872"
     CDS             68..682
                     /locus_tag="TV193_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514025.1"
                     /translation="MAYKLYTKADVGDNMLLVVGHLPDNTKRLKIQRETLDVLSITHY
                     SSYDMVQLKSTVKRSHSKNTVVTLVAAAASKPKAKPKHVLNFAKANKVYLGSTRVIAV
                     YLGDRLLWSDKDSSGNKTVSVVGSLDIRQSQKMLYLYLIASDIADVKSKRIKSIAING
                     VNLSSAAQINFEDSDYYCLVTIERVANIKEIKNIAQKNKITLEF"
     gene            693..>2476
                     /locus_tag="TV193_001873"
     CDS             693..>2476
                     /locus_tag="TV193_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1514026.1"
                     /translation="MSRDPTIVIDETNLVIGTDGRMHYTFTASQDNQKVRLKSNCLGT
                     AHFNQLMIERGDQATDYVAPVVVEGTGQATGVFKSLEEMLSGLKSIKLELTDTKNSNL
                     WSKIKLTTNGLLREYHHDHISTEIVETAAGIAKRIVDDTGQKLALINETIKGVKREYQ
                     DADRQLSASYQASIDGLKAQLANDKIGLQAEIKLSAQGLSQKYDDELRKLSAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIKDRAGAV
                     SRVQQDLDSYQRRLQDAEDNYSSLTQTVKGLQSTVSDPKGKIQSRFTQLQGQIEHRVT
                     RDGVMSIINESGDSIKLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNT
                     TVNGAFGAKLGEFIKLKADQIIGGSIDAAKIRVINLNASSIVGLDANFIRAKIEHTIT
                     SLLEGKVIRARNGAMMIDLSNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSHAT
                     PKNYTGSALYASIGITSSGDGINSASSGRFCGARFFRYARGYEHTALVDQAEIYGDDI
                     VFSDDFNIDRGFKMRPSLMPKMVDLNKM"
BASE COUNT          777 a          501 c          593 g          605 t
ORIGIN      
        1 caatcagagt atgatgatct gtatgattac agcgacaatg agttgatact cgtgacggag
       61 ggttgacatg gcatataagc tttacactaa agctgatgtt ggtgacaaca tgttgcttgt
      121 tgttggccat ttgcctgaca atacaaagcg attaaaaatc cagcgtgaga cgttagatgt
      181 attgagtatt acccactata gctcttatga tatggtacaa ctcaagtcga cagtcaaaag
      241 atcccacagc aaaaatacag ttgttactct tgtagctgca gctgctagca agcccaaagc
      301 taagccaaag cacgttttaa actttgctaa ggctaataag gtctatctag gcagcactcg
      361 tgtaatagcg gtttatctgg gtgatcgact gctctggtcc gacaaagaca gcagcgggaa
      421 caaaactgtc tctgttgtgg ggagtcttga tatcagacaa tcacaaaaaa tgctgtattt
      481 gtacttaata gcgtcagaca ttgcagatgt caaaagcaag cgcattaaat cgatagcgat
      541 aaatggcgtt aacctgtcaa gcgctgcaca aatcaatttt gaggatagcg actattattg
      601 tctagtgaca atcgagcgag ttgctaacat caaagagatc aaaaatatag cgcaaaaaaa
      661 caaaatcacg ctagagtttt aggaggtaac aattgagcag agacccaaca attgtaatag
      721 acgagacaaa cctcgttatt ggcacagatg gccgcatgca ttacacgttt actgctagtc
      781 aagacaacca aaaggtcagg ctaaaaagca actgtttagg cacagcgcat tttaaccagc
      841 tgatgattga gcgaggagac caagcgacgg actacgttgc gcccgttgtt gttgagggta
      901 caggacaggc aacaggcgtc tttaaaagtc tcgaggagat gcttagtggc ctaaagtcaa
      961 ttaaactgga gctaacagat accaaaaact caaatctgtg gtcaaaaatc aaattgacga
     1021 caaatgggct tttgcgtgag tatcatcatg atcatatctc gaccgagatt gtcgagacag
     1081 cagctggtat tgccaaacgg attgtcgatg atactggcca aaagctggca ctaatcaatg
     1141 agactatcaa aggtgttaag cgtgagtatc aagacgcaga tagacagcta tccgcgagct
     1201 atcaagcaag tatcgatggc ctcaaagccc agctggccaa cgacaaaatt ggcctacaag
     1261 ctgagattaa gctgtccgcc caaggcttgt cgcaaaaata cgacgatgag ctgcgcaagc
     1321 tatctgccaa gattacaacg acatctagtg gtactacgga agcctacgaa aacaaactcg
     1381 agggcttacg ggctgagttt actcgtagca accaaggcat gcggacagag cttgagtcgc
     1441 aaatcagcgg cctaaaagca gtacagcaat caactgcaaa acaaatctca caagagatca
     1501 aggatagggc aggggctgtt agtcgtgtgc aacaggatct agatagttac caaagacgct
     1561 tgcaagacgc agaggataat tacagtagct taacccagac cgttaaaggc ctgcagtcaa
     1621 ctgttagcga tcccaaaggc aaaatccagt cacgatttac acagctgcaa ggtcaaattg
     1681 agcatcgtgt gactagagat ggggttatga gtatcatcaa cgagtcaggc gatagcatta
     1741 agctagcgat ccaaaaggct ggtgggattg atgctaagat gagcgctaaa gagattatct
     1801 cagcgattaa tcttaatggt tatggcgtca gaatctccgg tgagcgtatt gcgctggacg
     1861 gtaatacgac cgttaacggg gcttttggag ctaaacttgg tgagtttatc aagctcaaag
     1921 ccgatcaaat tattggtggt tcgattgacg ctgctaagat tagagtgatc aatcttaacg
     1981 ctagcagcat tgttggctta gacgctaact ttatcagagc taaaattgag catacgatta
     2041 caagtttgct tgagggtaaa gttatcagag ctcgcaacgg agcgatgatg attgacttgt
     2101 caaactctaa gattgacttt aacagcaacg ctaccattaa ctttaataac aaagacaacg
     2161 ctttggtacg taaagatggc acacacactg cctttgtgca ctttagccat gcgacgccta
     2221 aaaactatac aggatctgcg ctatatgcat ctattggtat tacctcgtca ggtgacggga
     2281 ttaacagtgc gtcgagcggt cgtttttgcg gcgctaggtt ttttaggtat gcgcgaggtt
     2341 acgagcacac agcgcttgtt gaccaagctg agatttacgg tgatgacatt gtctttagcg
     2401 acgactttaa tattgatcgt ggctttaaga tgaggcctag cctaatgcca aaaatggtcg
     2461 atctcaataa gatgta
//
LOCUS       DARYXS010000144         2472 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.145, whole genome shotgun sequence.
ACCESSION   DARYXS010000144 DARYXS010000000
VERSION     DARYXS010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2472
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.145"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            50..1003
                     /locus_tag="TV193_001874"
     CDS             50..1003
                     /locus_tag="TV193_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1514027.1"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAIRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            1063..2262
                     /locus_tag="TV193_001875"
     CDS             1063..2262
                     /locus_tag="TV193_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1514028.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKQTIS"
BASE COUNT          730 a          440 c          557 g          745 t
ORIGIN      
        1 ggctagtggt attcttttca tttcagcctt attttgatat gatagacgta tgaattttga
       61 aaagattgaa caagcctatg agcttatatt agaaaatagc cagctgattg aaaatgattt
      121 aaaaacgcat atctatgatg ctattgttga gcagaattct ttttatctgg gagcccaagg
      181 agcaagccct caggttgcta aaaatattga gacgttgaag gccttgcagt taaccaagga
      241 ggagtggcgc caggcttatc agtttgtttt gatcaaggct gggaaaacag agccattaca
      301 ggccaaccac caatttaccc cagacgcgat cggctttatc atgctttata ttttggagac
      361 cttgagctca caagagtcac ttgatgtgct tgagattggc agtggaacag gtaatttagc
      421 tcaaactatt ttaaaccact cacataagag cattgattat ttaggcattg agcttgatga
      481 tttactaatt gatctatcag ctagtatcgc tgaaatcatg gggtcatcag cccagtttat
      541 tcaagaggat gctatcagac ctcagctgtt aaaagaaagt gatctcatca ttagcgattt
      601 gccagttggt ttttatccta acgacgatat tgctagcagg tatcaggtgg ctagctcaga
      661 tgagcatacc tatgcccatc atttactgat ggagcaagcc ttaaagtacc tgaaaaaaga
      721 tggctttgct attttcttag caccggtaaa tcttttgagc agcccacaaa gtcacctctt
      781 aaaacaatgg ctgaagggct atgctcaggt tgtggccttg attactttgc ctgaggctgt
      841 gtttggaaat ccagctaatg caaaatcgat tattgttctt tgtaagcaat cgaatcgctt
      901 tgcagaaacc tttgtttacc ccattaggga tttgaaatct gttgataatg ttcgtgattt
      961 tatggaaaac ttcaaaaatt ggaaacggga taatgttatt taagagaatt ttttgatata
     1021 atagaaaagc attgcagaaa acgatttcaa gagaggtaaa acatgtcaaa gacaattgca
     1081 attaatgcag gaagctccag cttaaaatgg cagctatatc aaatgccaga ggaaaaggta
     1141 ttagcacagg gaattatcga acgtatcggt ctgacagact caatctctac tgttaaatac
     1201 gatggcaaaa aagaagagca tattcttgat attccagatc atacagaggc tgttaagcgc
     1261 ttgttgaatg atttgattca ttttggcatt attggtacgt atgacgagat cacaggtgtt
     1321 gggcaccgta ttgttgcagg tggtgaatac ttcaaggaat ctgtggttgt tgatgataag
     1381 gttgttgagc aggttgagga gttagcagcc ttggcaccct tgcacaatcc gggggcagca
     1441 gcaggtattc gtgcctttcg taagattttg ccggacatta cgagtgtttg tgtgtttgat
     1501 acttcgtttc ataccacaat gcaaaagcat acctaccttt atccaattcc tcaaaaatat
     1561 tatacagatt ataaggttcg caagtacggg gcgcatggga ctagccataa atatgttgct
     1621 gaggaagcag caaaaatgct gggtcgccct ctagacgaat taaagctcat tacagcccat
     1681 gttggtaatg gtgtgtctat cacagccaat tatcatggtc agtcagtgga tacctctatg
     1741 ggctttacac cgcttgctgg tccgatgatg gggacacgct ctggtgatat tgatcctgct
     1801 attattcctt atttgattgc tcaggatcct gagctaaagg acgcagcaga tgtggtcaat
     1861 atgcttaaca agcaatctgg attaggtggt gtgtctggta tttccagtga tatgcgtgat
     1921 attgaggctg gcttgcaggc taacaatcca gatgccgtct tagcttacaa tatctttatc
     1981 gatcgtatca agaaatttat cggacaatac tttgcggtat taaatggtgc agatgccttg
     2041 gtctttaccg caggtatggg tgagaatgct cccttgatgc gccaagatgt cgtcaatggc
     2101 ttgtcatggt ttggtatgga aattgatcca gagaaaaatg tgtttggtta tcgtggtgat
     2161 atttcaacag cagcttcaaa ggtgaaggtg cttgtcatct caactgatga agagctgtgt
     2221 attgcgcgtg acgttgaacg cttgaaacag actatatcat aatctgataa tatactctta
     2281 gctcagctga tcagttttaa agagtccaaa aaatactttt aattggtacc gacctccaaa
     2341 agttagactt aaaggtttaa cgattggagg tcggtattat tatatagcca aatattctca
     2401 agacaaagac agccaaaaaa tgagacggtc gtaaccgtct caaaaaagtt taatttaatt
     2461 aaaaacattc at
//
LOCUS       DARYXS010000145         2436 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.146, whole genome shotgun sequence.
ACCESSION   DARYXS010000145 DARYXS010000000
VERSION     DARYXS010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2436
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.146"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..205
                     /locus_tag="TV193_001876"
     CDS             <1..205
                     /locus_tag="TV193_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1514029.1"
                     /translation="VQAVNVLKILVMAIGAGLGAWGVINLLEGYGSDNPGAKSQGIKQ
                     LMSGGGIVLIGLKLIPLLANVLR"
     gene            205..1068
                     /locus_tag="TV193_001877"
     CDS             205..1068
                     /locus_tag="TV193_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514030.1"
                     /translation="MFDLFGKIEEFFKDIMIDIIKDNLSAMLVDINDKVGTVAGEVGK
                     TPSSWNSEVFTFIKSINTNVVLPIAAIILTAILCIELIQVVMRKNSMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFDFSMAVFDVAQSMIGKAAGVVGTSANITPGNFDAMVEALKTKE
                     LGTLIGIALETGLVKFSLTILSILITVILYGRMIEIYIYCSVAAIPFSTMGNKEWSNI
                     GTNYIKSLFALGLQGLFILIFFGIYAVLVKTVNFTDIHTSILQVLAYGLILGVMMMKS
                     GSIAKAILNSH"
     gene            1141..1635
                     /locus_tag="TV193_001878"
     CDS             1141..1635
                     /locus_tag="TV193_001878"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1514031.1"
                     /translation="MNKINKKTRILIGAGSALSIGTIITVLLKKKTKKLSDLEEDDFD
                     FDFDEIEEDSCVNDKFATENDKDDTVKGEIDFLVDESKTENEKQEEFRDLSVKVMDLL
                     LKEVISMSETLNLVKRDIDRIGEVKALVEELENCKEEIISLWEHMEKLSDLREEITGK
                     KNRG"
     gene            1639..2049
                     /locus_tag="TV193_001879"
     CDS             1639..2049
                     /locus_tag="TV193_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1514032.1"
                     /translation="MAYVKIPKDLTKVKTKVALNMTKRQLIGFSIAGLIGFPVYMLCK
                     NFLSTDISMIIMSIVVLPVLFVTLYEKDNLPFEKHLAYILRFHKSKKIRLYKARSIYH
                     TERAKKQDIGNKNKASGRRKKVEQRQKKKTGTTN"
     gene            2009..>2436
                     /locus_tag="TV193_001880"
     CDS             2009..>2436
                     /locus_tag="TV193_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEL1514033.1"
                     /translation="MNKDKRKKQEQRIKKDELELRKNRKELSELKKTGKKKTKSKTKG
                     KSSKKNGWFPFFMKEEKKETVQDTIPYKRMLKDGICQIEKNKFNKTIRFLDINYRLME
                     EIDQEGIFSEFSSFLNFFDSSVEVEFSYINSIGENEEINKL"
BASE COUNT          916 a          315 c          512 g          693 t
ORIGIN      
        1 tgtacaggca gtaaatgtgc ttaaaatttt ggttatggca atcggtgcag gacttggtgc
       61 atggggagtt atcaacttac ttgaaggata cggatcagat aatcccggtg ccaagtcgca
      121 aggaatcaag caattgatga gcggtggagg aattgtttta atagggctga aactaattcc
      181 gctacttgct aatgtcttga gataatgttt gatttatttg gaaagataga agagtttttc
      241 aaggatatta tgattgatat tattaaagat aatctttctg caatgcttgt ggatattaat
      301 gataaagtag gaaccgttgc aggagaagtg ggaaagactc cgagttcttg gaactcggag
      361 gtcttcacct tcattaaatc aatcaatacc aatgttgttt tacccatagc agcgataatt
      421 ctaaccgcaa tactttgcat agaactgatt caggtggtaa tgagaaaaaa ttctatgcac
      481 gatacggata cctttgaatt ttttaagtac attattaaaa tgtggatagc tgtatggctt
      541 gtgtctcatg cgtttgattt ttcaatggca gtctttgatg tggcacagtc catgatagga
      601 aaggcagcag gtgttgtggg gacaagtgcg aatatcacac cgggaaattt tgatgctatg
      661 gtagaagccc ttaaaacaaa ggaacttgga acactcattg ggattgcact ggagacggga
      721 ttagttaaat tttctttaac gattctatca atcttaatca ctgtaatcct atatggaaga
      781 atgattgaga tatatatcta ttgctctgtt gcggcaattc cattttctac gatgggaaat
      841 aaagaatggt caaatatcgg aacaaactat ataaaaagtc tatttgccct tggacttcag
      901 ggacttttca tcctaatatt ttttggaatt tacgcagtct tagtcaaaac cgtaaacttt
      961 acggatatcc acacaagtat tttacaggta ttggcatatg gattgattct tggagtaatg
     1021 atgatgaaat ccggaagtat agcaaaggcg attttaaaca gtcactaaag gactttagtt
     1081 caaaatgagc aaaagttgat gaaataatca gaacaaaaaa tataattatt ggaggtaaga
     1141 atgaataaaa taaataaaaa aacaaggatt ttgataggag caggctcagc cctttctatc
     1201 gggacaatta ttacagtgct attaaaaaag aaaacgaaaa aattatccga tcttgaagaa
     1261 gatgattttg actttgattt tgatgaaata gaagaagatt cttgtgtcaa cgataaattt
     1321 gctacagaaa atgataaaga tgatacagta aaaggagaaa tagatttttt agtagatgaa
     1381 tcaaagacgg agaacgaaaa gcaagaagag tttagagatt tatcggtaaa ggtaatggat
     1441 cttcttctaa aagaagtaat ttcaatgagt gaaaccttaa atttggtaaa aagagatatt
     1501 gatagaatag gtgaagtaaa agcattggtt gaagaactgg aaaactgtaa agaagaaatt
     1561 atctcacttt gggagcacat ggaaaagtta tccgatttaa gagaagaaat taccggcaaa
     1621 aagaatagag gttaggctat ggcttatgta aagataccaa aagaccttac aaaagtaaaa
     1681 accaaggtag ccctgaatat gacaaaaagg cagcttatag gttttagcat agcagggctt
     1741 atcggttttc ctgtatatat gctgtgtaaa aattttctta gtacagatat ttccatgatt
     1801 ataatgagta tagtagttct acctgttctt tttgtaacgc tttatgaaaa ggacaattta
     1861 ccttttgaaa aacatttagc atatatcctc aggtttcata aaagtaaaaa gatcaggcta
     1921 tataaagcga ggagcattta tcatacagag agagcaaaaa agcaagatat aggaaataaa
     1981 aataaggcaa gcggaaggag gaaaaaagtt gaacaaagac aaaagaaaaa aacaggaaca
     2041 acgaattaaa aaggatgagt tggagcttag gaaaaataga aaggagctat ccgaacttaa
     2101 aaaaacagga aagaaaaaaa caaagtctaa aacaaaaggg aaatcatcga agaagaatgg
     2161 gtggtttcct ttttttatga aagaggagaa aaaagaaacc gtacaggata ccattccata
     2221 taagcgaatg ttaaaagacg ggatttgtca aattgaaaag aataagttta ataaaaccat
     2281 tcgatttttg gacattaact atcgcttaat ggaagaaata gaccaagagg gaatattttc
     2341 ggaattttct tcttttctaa atttctttga ctcatctgtg gaagtggagt tcagctatat
     2401 caacagtatc ggagaaaatg aagaaatcaa taaact
//
LOCUS       DARYXS010000146         2386 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.147, whole genome shotgun sequence.
ACCESSION   DARYXS010000146 DARYXS010000000
VERSION     DARYXS010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2386
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.147"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..902)
                     /locus_tag="TV193_001881"
     CDS             complement(<1..902)
                     /locus_tag="TV193_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004819958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL1514034.1"
                     /translation="MSKLEEAKNILNELKVPPKQQSDLCGYVILAMADIKKNDEWANA
                     TNKWIRIHDVIAFIREFYEVSYAENSRETFRKQAMHHFRNAAFIEDNGKATNSPNYRY
                     RLTDEMLLLVKTFQSSLWEEQKNNFLKSHQNLIDLYSSKKAVRKMPVKINGDDFTFSP
                     GKHNQLQKFIIEEFAPRFAENSECLYVGDTIQKDLVKNEEKLKELGFEITLHDKMPDV
                     VLYSEDKNWIYFVESVTSVGAMEPKRIKEIEEMTENVSAGKIYVTAFLDFKTFKKFSE
                     SLAWETEVWIADMPDHMIHLNGDK"
     gene            complement(895..>2386)
                     /locus_tag="TV193_001882"
     CDS             complement(895..>2386)
                     /locus_tag="TV193_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEL1514035.1"
                     /translation="KIIDYVIESTNKYIKQMPKEIRKKNGQFFTSKETALFMASLFDL
                     SSFSKEISILDPGAGSGILTAALIQRIIDTDKIEAIKITCYETNDDILELLNANLSWI
                     SKNTSLKIEYKVIKDNYITSQTLEYNNMLGVSTKPEKYDVIIGNPPYLKVGKMANEAL
                     SMPDICYGSPNLYFLFMEMASFNLVDNGELVFIVPRSWTSGAYFKKFREKFLNEVVLK
                     HIHLFVSRDKVFDKESVLQETMIIKAKKELNKLKNITITTTNDNFDFGSKTVFEASYD
                     MVVSGEHKYVFLITDKEEADTIKKVNEWNDTLPTLGLKMKTGLTVDFRNQEALRNDAE
                     EKAVPLFYSQHIKDGKVIFPVGKENEYLLTEKKGLLQENTNYLFVKRFTAKEEKRRLQ
                     CGIYLAKKFPTYKAISTQNKINFITGLQGLSDCLVYGLYVVLNSTLYDNYYRILNGST
                     QVNATEINSMPIPPLTCIEDMGKELIKLKDMSEENCDEILGRFIYV"
BASE COUNT          745 a          458 c          288 g          895 t
ORIGIN      
        1 aatttatcac catttaaatg aatcatatgg tcaggcatat ccgcaatcca tacttccgtt
       61 tcccaagcta aagactctga gaatttttta aatgttttaa agtctaaaaa tgctgttaca
      121 tatattttcc cagctgaaac attttccgtc atttcttcaa tttcttttat tcgctttggc
      181 tccattgcac ccacagaagt tacagactca acaaagtaga tccagttctt atcttctgaa
      241 tataaaacaa catccggcat tttatcatgg agtgttatct caaagccgag ttcttttagt
      301 ttctcctcat tcttcaccaa atccttttga attgtgtcac caacatacaa acattcagag
      361 ttctcagcga atcgtggagc aaattcttca ataataaatt tctgtaattg attgtgtttg
      421 ccgggagaaa atgtaaaatc atctccgttt attttaacag gcatttttct taccgccttt
      481 ttagagctat atagatcaat taagttctga tgagatttta agaaattatt cttctgttct
      541 tcccacagac ttgattgaaa tgtttttact aataacaaca tttcatcagt taatcgatac
      601 ctgtaattag ggctatttgt tgctttccca ttatcttcaa taaatgctgc attcctaaaa
      661 tgatgcattg cctgtttacg gaatgtttct ctactattct ctgcatatga aacctcataa
      721 aactctctaa taaaggcaat aacatcatga attcttatcc atttattagt tgcattagcc
      781 cattcatcat tctttttaat atctgccatt gccaaaataa catatccaca tagatccgac
      841 tgctgttttg gtggaacttt caactcattc aaaatattct ttgcttcttc taatttagac
      901 atatataaat ctccctaata tttcatcaca attttcttca gacatatcct ttaatttaat
      961 cagttccttt cccatatcct caatacaagt tagtggtgga attggcatcg agttaatttc
     1021 agtagcatta acttgagttg atccatttaa aattctgtaa taattatcat aaagcgtaga
     1081 gttcaataca acatacaaac cataaaccaa acaatctgat aatccttgta agcctgtaat
     1141 aaaatttatc ttattctgtg tgctaattgc cttatatgtt ggaaattttt tagctaaata
     1201 aattccacat tgtaatctac gcttttcttc ctttgccgta aatcttttca caaataaata
     1261 attagtgttc tcctgcaata atcctttttt ctccgttaat agatactcat tttcttttcc
     1321 aacaggaaaa atcactttac catcttttat atgttgcgaa taaaataaag gaactgcttt
     1381 ttcctctgca tcatttctta aagcctcttg atttctaaaa tcaactgtca aaccagtttt
     1441 cattttcaag ccaagagttg gcaaggtatc attccattca tttacctttt taatcgtatc
     1501 agcttcttct ttatcagtta tcaaaaaaac atatttgtgt tctccggaaa caaccatatc
     1561 gtaagaagct tcaaaaacag tcttgctgcc gaaatcaaaa ttatcattcg ttgtagttat
     1621 agtaatgttt tttaacttat ttaattcttt cttggcttta ataatcatag tttcttgcaa
     1681 aacagactct ttatcaaaga ctttgtctct gcttacaaat aaatgaatgt gcttcaaaac
     1741 cacttcattt aaaaacttct cacgaaactt tttaaagtac gctccagaag tccatgatct
     1801 tggaacgata aacaccaatt cgccattatc aaccaaattg aaacttgcca tctccataaa
     1861 aagaaaatat aaattcggtg atccataaca aatatcaggc atggataaag cttcattagc
     1921 catttttcca acctttaaat aaggtggatt tcctataatt acatcgtatt tttcaggttt
     1981 agtactcacc cccaacatat tgttatattc aagtgtttga cttgttatat agttatcttt
     2041 aatcactttg tattcaattt ttagtgatgt attcttactt atccacgata aatttgcatt
     2101 taacagctct aaaatatcat cattggtttc ataacaagta atttttatgg cttcaatctt
     2161 atcagtatca ataattcttt gaataagagc tgccgtaagt attcctgaac ccgctcccgg
     2221 atcgagtata gaaatttctt ttgaaaatga tgataaatca aataatgatg ccatgaaaag
     2281 agctgtttct ttacttgtga aaaattgccc atttttcttg cgaatttctt ttggcatctg
     2341 tttaatatat ttatttgtag attcaattac ataatcaatt attttc
//
LOCUS       DARYXS010000147         2304 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.148, whole genome shotgun sequence.
ACCESSION   DARYXS010000147 DARYXS010000000
VERSION     DARYXS010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2304
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.148"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..805)
                     /locus_tag="TV193_001883"
     CDS             complement(<1..805)
                     /locus_tag="TV193_001883"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514036.1"
                     /translation="MSVQVALKKALKPTWKRKLRQSWSIQRSTHLFSWYMVKHMDLTS
                     FRYVETNDYVLPEYGFKIHISGTFQNYKAIFSVVFPYLKCHHISFKYLKDEKMILENV
                     SDMEDPSESGKFITIYPRDREHCKQLLSDLYELIPVETEGVYILSDRNYKDSNVIFYR
                     YGLIEPREKVFVNAVPILIGPNGEQWQDFQKCYFDLPHWIEDLQEKQILLSSYLSENY
                     QVESLLKQSNGGNIYKAIHLDTGKNVVIKECRSHIICTASISKKQLRDNE"
     gene            complement(1221..2087)
                     /locus_tag="TV193_001884"
     CDS             complement(1221..2087)
                     /locus_tag="TV193_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL1514037.1"
                     /translation="MQYMGEMFKLLRTSRHISLKEATGDDFSHSMLSRFENGESDITI
                     SKLLVGLSNIRTELNEFIYLANGFKPSPYAVLKQEIWEAISKKDLSSLHQLYTKELEQ
                     YHLYKKDIYFLNALMIKSQMLFLDENIKMTPDEQSFLYDYLFSVEIWGIYELQLFSDI
                     SPLLSLDVYLRYTREMLGRVDFFEELWQHRNLVHSILLNGLFKATQEKRLGIAAYFDK
                     MINNHFFEENDTYLRIVYMIADGQHLYCKGEKELGLKQINDAIHILKALNCDESAAYY
                     SDSLEKWLKEVE"
BASE COUNT          728 a          441 c          310 g          825 t
ORIGIN      
        1 attcgttatc tctcaactgt tttttactaa tactagctgt acagataata tgagagcgac
       61 attctttgat aactacattt tttccagtat ctagatgaat agctttataa atatttccac
      121 cattagattg ctttagtaag ctttccactt gataattttc acttaaatat gacgacaata
      181 aaatctgttt ttcttgtaaa tcttcaatcc aatgaggtaa atcaaaataa cacttctgga
      241 aatcctgcca ttgctctccg tttggtccaa ttaatattgg aactgcattt acaaaaactt
      301 tttctctagg ttcaataagt ccatacctat aaaaaataac atttgaatct ttatagtttc
      361 tatcactaag tatatagact ccttctgtct caacaggtat caattcatac aagtcactta
      421 ataattgttt acagtgttct ctatctctgg gataaattgt gatgaatttc ccagattccg
      481 aaggatcttc catatcggat acattttcta aaatcatttt ttcgtctttt aaatatttaa
      541 aagaaatatg atgacatttt aaatacggaa atactacaga aaaaattgct ttatagtttt
      601 gaaatgttcc tgaaatatga attttaaatc catattcagg taaaacataa tcattcgtct
      661 ctacatatct aaagcttgtc agatccatat gcttcaccat gtaccagctg aataaatggg
      721 tacttctctg gatgctccat gattgtctta actttctttt ccacgtaggc ttcaaagctt
      781 ttttcaaagc tacttgaaca ctcacgagaa tcttctttat agatacattt ttaagtaatc
      841 attggttttc tcatagcaat acatctcctc agtcttatta gtataaaact aaaaacgctc
      901 acattaacag gtctttttga gcgtttttag taggactagt tactaaatta tggtttgtag
      961 attggacatt tccaagtcac aacaaagcct ttcactggcg caaagcatct actagcctcg
     1021 tatgcaaatt gagtcatgtt tgtgatctcc tttcattctt gatgagtcta gtgtatcatc
     1081 aaaaaccgta ccaaagctaa actgttcata tgttcaaatc atggttttga cattaatcaa
     1141 aaaacagtag ctcaaaaagc cactgtttgc tactagctaa gcatctaaac cattttgctt
     1201 atcaatgctt taagttgcat ttattcaact tcctttaacc atttctctaa actatctgaa
     1261 taataggctg cactttcatc acaatttaat gcctttaaga tgtgtatggc gtcatttatt
     1321 tgctttaagc ctagttcctt ttccccttta caatataggt gctgaccatc agcaatcata
     1381 taaacaattc ttaagtaggt gtcattttct tcaaaaaaat gattgttaat cattttatca
     1441 aaatatgcag ctatacctag ccttttttcc tgagtagctt taaacagccc atttaataaa
     1501 atgctgtgca ctaaatttcg atgctgccaa agctcctcaa aaaagtctac tcttcctagc
     1561 atttctcgag tataccgcaa atacacatcc aaggataata agggagaaat atctgaaaat
     1621 aattgtaatt cgtatattcc ccaaatctcc actgaaaaca aataatcata taaaaagctt
     1681 tgctcatctg gagtcatttt gatattctcg tctaaaaaga gcatttggct tttaatcatc
     1741 aaagcattta aaaaatagat atcctttttg tataaatgat actgctccag ctcttttgta
     1801 tacaattgat gtaagctgga caggtctttt tttgatatgg cctcccagat ctcttgcttt
     1861 aggacagcat atggggaagg cttaaagcca tttgctagat agataaattc attgagctct
     1921 gtccgaatat tgctaagtcc aaccaatagc tttgagattg ttatatcgga ttcaccattt
     1981 tcaaatctgc ttaacatcga gtgagaaaag tcatctcccg tcgcttcctt taacgatatg
     2041 tgtcgcgatg tccgcagtaa tttaaacatt tctcccatat attgcatatc aatacctctt
     2101 caatctttca ttttagtata gtatataacc ttaaaaatgt aaatccagtc ttgattgcat
     2161 aaacctttaa ttcaacgttt gatgctacta aatatcctat ttttctgaag tagatcctca
     2221 tctttatgct ataagcactt gctgcgtttt agaaaatggg ctaaatcagc tatactcctt
     2281 tttaataaca aaaaagcctt attt
//
LOCUS       DARYXS010000148         2258 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.149, whole genome shotgun sequence.
ACCESSION   DARYXS010000148 DARYXS010000000
VERSION     DARYXS010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2258
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.149"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            8..283
                     /locus_tag="TV193_001885"
     CDS             8..283
                     /locus_tag="TV193_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005606224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514038.1"
                     /translation="MKNRGFESLHYVLFDEEKRLPWAFHLYQKNGKFYVEGRDERSYI
                     IGHSREYRKFDDAKHELLKKLELVIESNRLKKQLGEPTEYPSPLWNE"
     gene            542..1171
                     /locus_tag="TV193_001886"
     CDS             542..1171
                     /locus_tag="TV193_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514039.1"
                     /translation="MTTLAGMSPEDSQRYIQWHKYAKAGLSPSDRVRILEISEKAPKI
                     EYLPGKTSDSILAISKGDRPNVEKVYSPDYIGFHRKQFDNGATRFQKFKPNVDYQDGL
                     VGDDLGNSFWLSTKDADIIQEIGKGNNRLYETLLGFDEGYLEDGPLYRLDVSPEVVSQ
                     KGVSIPSGNEKGANSWWRPGGRTYPGNIPEGVMQGISTKKGDHTWHAVN"
     gene            1153..1575
                     /locus_tag="TV193_001887"
     CDS             1153..1575
                     /locus_tag="TV193_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514040.1"
                     /translation="MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEEGGIAVQR
                     VVYELPYDLFELLESGERSLGDVHSKLQDGNWPPTEEEKKQSHRKFVIDTPTALIADP
                     TSVSLFSEEELSKLVPIAEQQWIDWKGKLPDDYVSPLK"
     gene            1834..2238
                     /locus_tag="TV193_001888"
     CDS             1834..2238
                     /locus_tag="TV193_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514041.1"
                     /translation="MSKNYTEADVAKLTELTTHNAKTKTALLGYYEANSVTSYEQIAH
                     QNKLTYFDAGSDGWNAMSRVDSKLAQRVNREFLIKQIEKRKTFILTSNPYTAQSIADV
                     SGIGKSYAKEIQILAENGYNIEKFERFWRAYK"
BASE COUNT          772 a          372 c          536 g          578 t
ORIGIN      
        1 agaagcaatt aaaaatcgag gttttgagag tttacattat gttttatttg atgaagaaaa
       61 gcgacttcct tgggcatttc atctttatca aaaaaatgga aaattctatg ttgaaggaag
      121 agatgagcga tcatatatca ttggtcatag cagggaatat cgtaaatttg atgatgccaa
      181 gcatgaattg cttaaaaaat tagaattagt tatagaatct aatcggttaa aaaagcagtt
      241 aggtgaacct acagaatatc cctcaccact atggaatgaa tgagtttcat gtattgtatg
      301 ccatggcacc aagcttttag gaggcagcga gcaagacgcc caaagagcaa cattagttgg
      361 gaatatccta ggaggacttg ccgcctcaag cgccgctaga aggttcagct tgaatgagcc
      421 aatagcaact agggtgacga aaccgaccca caaccgccag cagcttttga agaaccttga
      481 gaacagcaga ctggcaagag aaagctcaag gtttaagaat tatgtagcaa gagaaaaatt
      541 catgacaacc cttgcaggca tgagtcctga ggatagtcag cgctatattc aatggcacaa
      601 atacgcaaag gctggactta gtccgtcaga tcgagtaagg attctagaaa tatctgagaa
      661 ggcaccgaag atagagtatc ttccgggaaa aacatcagat agtatattgg caatatccaa
      721 gggtgatcgt ccaaatgtgg agaaagtcta cagtccagat tatattggat ttcatagaaa
      781 acaatttgat aacggtgcaa ctagatttca gaaatttaag cccaatgtag attaccaaga
      841 cggtttagtt ggtgacgatt taggcaatag tttttggtta agtaccaagg acgcggatat
      901 tatccaggag ataggaaagg gaaataaccg tctttatgag acactcttag gctttgatga
      961 agggtattta gaagatggtc ccctctatcg cttagatgtt tcaccagaag ttgtttcaca
     1021 aaaaggtgtt tcaataccaa gtggtaatga aaaaggggca aatagctggt ggcgtcctgg
     1081 aggtcgtact tatccgggga atataccaga gggagttatg caaggtatca gtacaaagaa
     1141 aggagatcac acatggcacg cagtcaatta gagtgggaag atgttagtca atatgaggag
     1201 gtaaagggct atggtcaaag ggtgtggaag catcaaggga aatattactt tgttgccgaa
     1261 gaaggtggca ttgctgttca acgagtagta tatgagttac cgtatgactt atttgaattg
     1321 ttggaaagtg gagaacgtag tcttggagat gttcattcaa agctacaaga tggtaattgg
     1381 ccaccaacag aagaggaaaa gaagcaaagt catagaaaat ttgttattga cacaccaact
     1441 gcgctgattg cagaccctac tagtgtgtct ctgttctcag aagaagaatt atcaaaatta
     1501 gtgccaatcg ctgaacaaca gtggatagat tggaagggaa agctgccaga tgattatgtc
     1561 agtcctttga aataatgttt aagatagcgg agccgagatt agctctgcta ttttaaagca
     1621 tgttcttaat aattagcctg cgacagctta tcagggagta gctcgtcacc ttgaagccaa
     1681 tgccaagcgt ctccaagcgc cgccagaagg ttcagcttga atgagccgat agcagctaaa
     1741 gtgacgaaat cagcgaaaat aaccctttct gaaaaggtac tagacacaaa ggttcggttt
     1801 gatgagtctc gcattgtggc ttacgcagaa agtatgagta agaactatac agaagctgac
     1861 gtggccaaat taaccgagct gaccacccac aatgcaaaaa ccaaaacagc tttgctggga
     1921 tattacgaag caaacagcgt tacttcgtat gaacaaattg cacatcaaaa taagttaact
     1981 tactttgatg ccggaagtga tggttggaat gcgatgtcga gagtggattc taagctagct
     2041 caaagggtta atcgtgaatt tttgataaaa caaattgaga aaagaaaaac atttatatta
     2101 acgtctaatc catatactgc tcaatcaatc gcagatgtta gtggtatcgg gaagtcttat
     2161 gctaaagaaa ttcagatttt agcagaaaat ggatataata ttgaaaaatt tgaaaggttt
     2221 tggagggcat ataaatgagt gaagaacagt atttacca
//
LOCUS       DARYXS010000149         2199 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.150, whole genome shotgun sequence.
ACCESSION   DARYXS010000149 DARYXS010000000
VERSION     DARYXS010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2199
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.150"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            181..1608
                     /locus_tag="TV193_001889"
     CDS             181..1608
                     /locus_tag="TV193_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1514042.1"
                     /translation="MERLMRTQLKKLLAGTAAGTLLLFNLTCGMINAFAEQYYGWSDG
                     SSSYPSALYVTPVGDTTKKIAIPVYCFDYKFQEPLAWKEITQPSHLIVYDKYDGKNLM
                     AALVEKPNMVSYETKTKLQTLLKTKSNLITAILSRGYPNKSFFDKYKKLTDEDKRRVT
                     QCALWYHTDNISEQDLITKHLDGDSGEKSQALKELIGVVKNTSNELGEGLTFYTRYND
                     RYGPKYQNLIGSIIVPEEPQNDLEIGGGNVIDLNYQSGPMVEEGGHSGGKEEVEDTKK
                     PDVIIGGQGSVTETTEDTQKGMSGSTETQPEVEDTKQPQSDIILGGQGNVIDTTENTQ
                     EGMGGQSGDTTETEDTKQPQSDIILGGQGNVIDTTENTQEGMSGSNNGQTFEEDTRPK
                     LEFHFDNEVPNDDDAPKPEQPEQPEKPEQPRKPQQEQQSLPRPIEGNQSLPKTHEAKG
                     VLALVGVGILAMLGLGFWFRPYQKD"
     gene            1874..2143
                     /gene="rpsO"
                     /locus_tag="TV193_001890"
     CDS             1874..2143
                     /gene="rpsO"
                     /locus_tag="TV193_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEL1514043.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
BASE COUNT          769 a          382 c          486 g          562 t
ORIGIN      
        1 taatagataa aaaatgataa tcgttcgtaa ataaatcaaa catctaatct aaaaaaatta
       61 tattgttctg attgttcggt aattaaagca atagcgcttg tcgaaaaact aatgttctct
      121 taatatcagg tagccatgcc aagggttttg tgttaaagta taggacgttc aaaaaatgaa
      181 atggagagac taatgagaac acaattgaaa aaattgctgg caggaacagc agcaggtacc
      241 ctgctgctgt ttaacctgac ctgcggaatg attaatgctt ttgcagagca gtattacggg
      301 tggagtgacg ggagtagcag ctatccgagt gctttgtatg ttacaccggt aggagatact
      361 acgaaaaaga tagctattcc tgtttattgc tttgactata agtttcagga gccacttgct
      421 tggaaagaaa taactcaacc gtcacacttg attgtctatg ataagtatga tggcaaaaat
      481 ttgatggcag cactggttga aaaacctaat atggtaagct atgagactaa aactaaactt
      541 caaacacttt taaagacaaa gtcaaatcta ataactgcaa ttttaagtag aggttatcca
      601 aacaaaagtt tttttgataa gtataaaaaa ttaactgatg aagataaaag acgagtgaca
      661 caatgtgctc tttggtatca tactgacaat atttcagaac aagatcttat cacaaaacat
      721 ttggatgggg attcaggtga aaaaagtcaa gcgctaaagg agttaatagg ggttgtaaaa
      781 aatacttcta atgagttagg agagggatta accttctata ctcgttataa tgatagatat
      841 ggtcctaaat atcaaaacct aataggctca attattgttc ccgaagagcc tcagaatgat
      901 cttgaaattg gtggtggaaa tgttattgat ttaaactacc aatctggacc aatggtagaa
      961 gaaggtggtc attcaggtgg caaggaagag gtcgaggaca ctaaaaagcc tgatgtgatt
     1021 attggtggtc agggaagcgt tactgagact actgaggata ctcaaaaggg tatgagtggc
     1081 agtactgaga ctcagccaga ggttgaggat actaagcagc cacaatcaga tattatccta
     1141 ggcggacaag gcaatgtgat tgacacaact gaaaataccc aagagggcat gggtggccaa
     1201 tcaggtgata ctacagagac tgaggatacc aagcagccac aatcagacat tatcctaggt
     1261 ggacagggca atgtaattga caccactgaa aatactcaag agggtatgag tggttccaac
     1321 aatggtcaaa catttgagga ggacacacgt cctaagctgg aattccattt tgataatgaa
     1381 gtgcctaacg atgatgacgc tcctaaacca gagcaaccag aacagccaga gaagccggag
     1441 caaccaagga agccacagca ggagcagcaa agcctaccac gtccaataga gggcaaccag
     1501 tcattgccaa aaacacatga ggcaaaaggt gtactggctc tagtaggagt aggaatcctt
     1561 gctatgctag gactaggctt ttggtttaga ccttatcaaa aagactaaat caaggctcag
     1621 cagctattta agctaaacag ctgtgctcag ctaaatgata aaacaattaa gattggagaa
     1681 tgtggctatt agtagcttct ccaatctttt ttgatagcag catgtgcttt ttctgccgta
     1741 ttttattgag aataatagtt gaccagtcta ggcgattttg ctagaataga gaggtcgcaa
     1801 gacagactaa ctttttcttg gttttaggag tgccaaccct aaaactcgga ttaagcaaaa
     1861 aaggagaatt attatggcaa tctcaaaaga gaaaaaaaat gaaattattg cacaatatgc
     1921 acgtcacgaa ggtgacacag gctcagttga ggttcaggta gctgtcctta cttgggaaat
     1981 caaccacttg aacaaccaca tcaaggagca caaaaaagac cacgcaactt atcgtggatt
     2041 gatgaaaaaa atcggacacc gtcgtaacct attagcatac ctacgtcgta cagatgttaa
     2101 ccgttaccgc gagttaatcc aatcacttgg acttcgtcgt taattggctt gacagaggtc
     2161 attttagaga taaccaagtt ctattgaaaa aagatctgc
//
LOCUS       DARYXS010000150         2126 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.151, whole genome shotgun sequence.
ACCESSION   DARYXS010000150 DARYXS010000000
VERSION     DARYXS010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2126
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.151"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..397
                     /locus_tag="TV193_001891"
     CDS             <1..397
                     /locus_tag="TV193_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1514044.1"
                     /translation="YVLTGGFLFTGFLLGLSFVLGAALIIYYKQYSEGYEDKKSYNIL
                     QEVGMSKQQVKKTINSQIVLVFFMPIAMAVLHFCVALVMLKQMLFLFGVLDTNLIYLV
                     SALTIAVIIVIYFTIYRITSKTYYNIIER"
     gene            441..1106
                     /locus_tag="TV193_001892"
     CDS             441..1106
                     /locus_tag="TV193_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1514045.1"
                     /translation="MIKAGKIYIVEDDAAILTPLKEHLSQNYQVLTVSNFRDIKQEVI
                     DYKPDIILMDITLPFFNGFYWTTEIRKTSTVPIVFISSSNDEMDTVMALNMGGDDFIS
                     KPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILT
                     ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDRIHTVRGVGY
                     IIK"
     gene            1103..2080
                     /locus_tag="TV193_001893"
     CDS             1103..2080
                     /locus_tag="TV193_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1514046.1"
                     /translation="MIRAFFKEYYSWYIQYGVVMAGYLLIFWLYRLPLGYFKVTSLTI
                     LTLLILQGFGNYIRFKKKMKILQEFIYVKELDQLHSPSEQAYRSLIIKLKEAEAEVAL
                     YQLNNQKNTEALIKMWSHQMKLPLAAMSLMLQTNHIDIKDYQIQVLRLEHYLNNLLSY
                     LKFNQHSDDFRFQVCSVKQLVTSVIKKSSQTCIAKGISIAVDGDWQLSTDNKWLSFAL
                     TQIIDNAIKYSKPQGHIKVSIKEGSIFISDNGIGILEEDLPRLFEEGFTGYNGHEHQK
                     ATGLGLFMTKQILDKLNLNITISSQVDQGTLVVIQKKHSKQTKFSTSLL"
BASE COUNT          685 a          393 c          388 g          660 t
ORIGIN      
        1 ctatgtccta accggtggct tcctttttac aggctttctt ttaggcttga gctttgtact
       61 tggggctgca ctgatcattt attacaagca atactctgaa ggctatgagg ataaaaaatc
      121 ttacaatatt cttcaagagg tcggcatgag caaacaacaa gtcaaaaaaa ccatcaattc
      181 ccaaattgta ttagtgttct ttatgcccat agctatggca gtcctacatt tttgtgtcgc
      241 tctggttatg cttaagcaaa tgctctttct ctttggcgtt ttagacacta atcttattta
      301 cctagttagt gcgctgacca ttgctgttat tatcgttatt tactttacta tttacaggat
      361 aacaagcaaa acctattaca atattattga aagataagac gagtggcgat ttttcgccac
      421 ttttttgata aaataatatt atgattaaag ctggaaaaat ttatattgtc gaagatgacg
      481 ctgctatctt aacaccctta aaagagcatc tgagtcagaa ctaccaggtt cttaccgtct
      541 ctaactttag agacattaag caagaggtga ttgattataa accggatatc atccttatgg
      601 acatcacctt accgtttttt aacggctttt actggacaac agaaattcgt aaaacgtcaa
      661 cagtgccaat tgtttttatc tcaagcagta atgatgagat ggatacggtc atggcactta
      721 atatgggggg agatgatttc atctctaaac ccttttctct aaccatttta gacgcaaaaa
      781 tcgcagcctt tttaagacgc tcacagcaat ttagcagtga tgatgtgacc atagatcaat
      841 ttaagctaca ttttgatggc accttatcta atggcacaga tagcattcat ttatcgccaa
      901 cagagcacaa aatcttaacg attttattta ctcacccgca gcaaattgtt tcaaaggagg
      961 atattctagc aaggctttgg gaaaacgaga gctttattga tcaaaacacg cttaatgtta
     1021 acatgacgcg tctacgcaaa aaaatatcag ctattggttt tgaccgtatt cacacagtga
     1081 gaggagtagg ctatattatc aaatgataag agcatttttt aaggaatatt attcctggta
     1141 tatccagtat ggggttgtta tggctggtta tctgctgatc ttttggcttt ataggcttcc
     1201 tttaggctat tttaaagtga ctagcctaac catactaacc ttgctaatat tgcaaggttt
     1261 tggaaactat attaggttca aaaagaagat gaagatttta caagaattta tttatgtaaa
     1321 agaactagat cagctgcact cccctagcga acaagcctat aggtctttga ttattaagct
     1381 taaggaagca gaagcagagg tagcactgta ccaacttaac aaccaaaaga atacagaagc
     1441 actgattaaa atgtggtctc accaaatgaa gcttccccta gcggctatgt ccttaatgct
     1501 tcaaaccaat catattgata ttaaggatta tcagattcag gttctacgct tggagcatta
     1561 cctcaacaat ctattaagct atttgaagtt taaccagcat agtgatgatt ttcggtttca
     1621 ggtttgctct gtaaagcagc ttgtgacctc agttatcaaa aagtccagcc agacttgtat
     1681 cgctaagggg attagcattg cagttgatgg cgattggcaa ttgagcactg acaacaaatg
     1741 gctgtcattt gctctgacac aaatcattga caatgcaatc aaatattcta agccacaagg
     1801 ccacatcaaa gtcagcatta aggaaggcag tatttttata tcagataatg gtattggaat
     1861 actagaggaa gatttgccac gtctgtttga agaaggcttt actggctaca atggccatga
     1921 gcatcaaaag gcaactggtt taggcctctt tatgacaaag caaatccttg ataaattaaa
     1981 tttaaacata actatttcca gtcaagttga ccaaggaact ttagttgtaa ttcaaaaaaa
     2041 gcattctaaa cagaccaaat tctcgacttc tttgctgtaa aaaataacag ctataaatcc
     2101 ctataatagt gacaaagagg attaaa
//
LOCUS       DARYXS010000151         2116 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.152, whole genome shotgun sequence.
ACCESSION   DARYXS010000151 DARYXS010000000
VERSION     DARYXS010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2116
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.152"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..1684)
                     /locus_tag="TV193_001894"
     CDS             complement(<1..1684)
                     /locus_tag="TV193_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEL1514047.1"
                     /translation="MQTLVISEKPSVAISISKVLGATKKKDGYNEGNGYRVSWCVGHL
                     IQMANPDAYDEKYAKWDMADLPIIPKDYKYEVAKATKKQFNILKKLMNDKEIDTVINA
                     CDAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDHLKDGKKYDNLFESAQ
                     ARAIADWLVGMNISRLYSCLYNQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVEL
                     SMDGFILSTDRIDDKVAAEQLINLVGDKIEITDVIQNEKITKPDLPFDLTTLQRECNK
                     YFGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMITSMINNILGQNDFDTGRIKVI
                     FNSSKVTDHHAIIPTVSSMSEDLLSIPESEAKVYGLIFNKLHASVGYPLIENTTKIVV
                     TFDGFKFTSSGKVIKDEGFTKYLKEYKTKKNEDIELPNVNIGDSLKIKDKEIKEKYTQ
                     PPKHFTENTLLKSMETAGNDALKKGIEVERKGIGTPATRAGIIENLIYKGFIQRDKKN
                     LVATHKGISLITIVADNFKSAETTAKWEMELSDISQGKSSKEEFLRRVEAEIR"
     gene            complement(1856..>2116)
                     /locus_tag="TV193_001895"
     CDS             complement(1856..>2116)
                     /locus_tag="TV193_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL1514048.1"
                     /translation="YIIYKLKDKDVNVEILREACRKTFSYRKTEFDIGKIIDLLEKLK
                     INEAFLKRWQAYSRKNLYAKDITFEEVLDNGIKMVEKIKNEN"
BASE COUNT          575 a          437 c          262 g          842 t
ORIGIN      
        1 ttcttatctc agcttctact cttcttaaaa attcttcctt tgaagatttc ccttgagaaa
       61 tatcagacaa ctccatttcc cactttgcag ttgtttcagc agatttaaag ttgtctgcaa
      121 caattgttat aagactaatt cctttatgtg tagctacaag atttttctta tctctttgaa
      181 taaagccttt gtaaattaga ttttctataa tccctgcacg agttgcgggt gtgccaatac
      241 cctttctttc aacctcaata ccttttttta aagcgtcatt tcctgctgtt tccatgcttt
      301 ttaataaggt gttttccgta aaatgttttg gaggttgcgt atatttttct ttgatttctt
      361 tatccttgat tttaagacta tcacctatat ttacatttgg aagttctata tcttcattct
      421 ttttcgtctt atattccttt aaatacttag taaacccctc atccttaatt acttttccgg
      481 aacttgtaaa tttaaagccg tcaaaagtca ctacaatctt tgttgtattc tcgattaaag
      541 gatagcccac acttgcgtgt aacttattaa aaataagtcc atacactttt gcttcactct
      601 ccggaatact caataaatct tcactcattg aacttactgt cggtataata gcatgatgat
      661 ccgttacctt gcttgaatta aaaatgacct taatacgccc tgtatcaaag tcattttgtc
      721 ccaatatgtt atttatcata cttgtaatca tatcttcagt aaggcatcta ctgtctgttc
      781 ttggataggt aataagtttc ttctcataca gactttgagc ataatcaaga gtctgcttag
      841 ctgagtatcc aaaatattta ttgcactctc tttgaagtgt tgtcaggtca aaaggtaaat
      901 ccggctttgt aatcttttca ttttgaatga catcggtaat ttcaatctta tcaccaacta
      961 aattgattag ctgctctgct gctaccttat catcaattct gtctgtggaa agtataaaac
     1021 cgtccataga tagctctaca gtataatatt tttctttttt aaagtttgct atctcgtcat
     1081 ctcgttttac aatcatggca agagttggcg tctgcaccct accgacagag taattttgat
     1141 tatataagca ggaataaagt ctactaatat tcattccgac taaccaatct gcaatggctc
     1201 ttgcctgtgc cgattcaaag agattgtcat atttctttcc gtcttttaga tgatcaaaac
     1261 cctctttaat cgcactatct tccatagatg aaatccaaag gcgtttcatt ttctttttac
     1321 aattcacttg attataaaca agtctaaaaa tgctctctcc ctcacgacct gcatcgcaag
     1381 catttataac cgtatcaatt tctttatcat tcatcagctt tttaaggatg ttgaattgct
     1441 tcttggttgc ctttgctact tcatacttat agtccttggg aataatcggt aaatcagcca
     1501 tatcccactt ggcatacttt tcatcataag catccggatt tgccatctga attaaatgac
     1561 caacacacca acttacccta tatccatttc cctcattata tccgtctttc ttttttgttg
     1621 ctccaagcac ctttgatatg cttattgcaa cactcggttt ttcacttatc accagtgttt
     1681 gcataaattc ctcctttttt ctacatgaaa aaagacaatc agagtttgca tttctccaat
     1741 tgtcttttaa agttttatat atttcatttt ctatttttta atccattttc ctgtttggga
     1801 actaacttac aaaaaaatgt ttgacgcctt cttttcattg taaaaccgtt atatgctaat
     1861 tttcattctt tattttttcc accattttta ttccgttgtc caatacttct tcaaaagtta
     1921 tatctttcgc atacagattt tttcttgaat aagcttgcca tcttttcaaa aaggcttcat
     1981 ttattttcaa tttttccagt aagtctatga ttttacctat gtcaaattct gtttttctat
     2041 aactaaaagt ttttctgcaa gcctctctta atatctctac atttacatct ttatccttta
     2101 atttataaat aatata
//
LOCUS       DARYXS010000152         2076 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.153, whole genome shotgun sequence.
ACCESSION   DARYXS010000152 DARYXS010000000
VERSION     DARYXS010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2076
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.153"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..857
                     /gene="galU"
                     /locus_tag="TV193_001896"
     CDS             <1..857
                     /gene="galU"
                     /locus_tag="TV193_001896"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEL1514049.1"
                     /translation="LPATKALAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKR
                     SIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFV
                     GNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAP
                     QGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIFAILENQAPGAGNEVQLTD
                     AIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKHPQVKDDLTDYIIKLGKAL
                     ESTQQQTK"
     gene            complement(964..1356)
                     /locus_tag="TV193_001897"
                     /pseudo
     CDS             complement(964..1356)
                     /locus_tag="TV193_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
     gene            complement(1353..1880)
                     /locus_tag="TV193_001898"
     CDS             complement(1353..1880)
                     /locus_tag="TV193_001898"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEL1514050.1"
                     /translation="MIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEAQT
                     LVTYLPLPHEYQSHLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFGLMEP
                     RCTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWEDF
                     VVEAHDIAVKEVYCQ"
BASE COUNT          617 a          516 c          458 g          485 t
ORIGIN      
        1 tcctgcctgc cactaaggca ctggccaagg aaatgctccc aatcgtcgat aagccaacca
       61 ttcaattcat cgtcgaggaa gccctaaagg ccggtatcga ggagattctt gtcgtcaccg
      121 gcaaggccaa acgctctatc gaagaccact ttgactccaa cttcgagctc gaatacaatc
      181 tccaagccaa gggcaaaacc gagctgctca agctcgttga tgagaccact gccatcaacc
      241 tgcacttcat tcgtcagagc caccctagag gactagggga cgctgtcctc caagccaagg
      301 cctttgtggg caatgagccc tttgtggtca tgctaggaga cgacctcatg gatattacca
      361 atcctagtgc caagcccttg accaagcagc ttatcgagga ttatgactgt acacacgcct
      421 caacgattgc tgtgatgagg gttccgcatg aggaggtttc caattatggc gtgattgcac
      481 cgcaagggaa ggctgttaag ggcttgtata gtgtggagac ctttgttgag aagccaagtc
      541 ctgatgaggc acctagtgac ttagcgatta ttggacgtta tttgttgacg cctgagattt
      601 ttgccatatt ggagaatcag gcgcctgggg ctggcaatga ggttcagctg accgatgcga
      661 ttgacaagct caacaagact cagcgggttt ttgccaggga gtttaaggga gagcggtatg
      721 atgttgggga caagtttggc tttatgaaga cctcacttga ctatgctctc aagcaccctc
      781 aggtcaagga cgacctcact gactacatta taaagctggg taaagcacta gaaagcactc
      841 aacagcagac aaaataggag ttggggcaac cgtcctagaa gcattaaaaa gcaacagcag
      901 caaaaccgtt gctttttgtt taaatcaaag atacacctgt cctagcactt ataagcttga
      961 aggaaaaaga ccaaaaagag aggtggaagc acctgctgct acggtatctg gtgtcagcca
     1021 catgataaaa gcattcccca taatccctga acacacatac agcagcaaaa actgtcttga
     1081 cccccaaatg gtctcagcca tccgcccgac aaaataaagg gttaaggtat taatgaaaaa
     1141 atgctcaaag ccaatatgaa ccactatagg tgtcaccaag cgccaaagct gatcaggcat
     1201 tgctctgaca acaagaccat tcatgccacc aaatataaca acagcataag ggtgcgtagc
     1261 aaactggcca tagaccagct gcattatcaa aaaaactaaa ccagtcaagc ccaagaaaaa
     1321 gagtgttatc gggtattttt tgatcatcag tctcattggc aatacacctc cttcacagca
     1381 atatcatgtg cctctaccac aaaatcctcc cactgacagg cataaatcgt gctaaaggta
     1441 gccccctgat aatccctcaa ataacgatca tagtagccac caccatagcc tatacgatag
     1501 cctgcagggt gaaaaacaag ccctggcaca tgaatggcat caatctccga cttagcaaca
     1561 gctatggtac acctaggctc cataagacca aaagccgtct gtatcaagtc acaaggatca
     1621 taagccacaa acaccatctc tccacgagaa cgagtcttgg gcacaaggat agtcttgccg
     1681 tcctgcaagg ctcgctcaat cagtagatgg ctttgatact cgtgtggcaa gggcagatag
     1741 gtcacaagag tctgcgcctc ttgatagctg ctactagcaa ctactgctgc caatagagct
     1801 aagtcctttt ccagcttatc ctctggggtc atcatggcta ggcgctgaag cactagttgg
     1861 cgataatctt ttttaatcat gcccatatca taacacaaag cgctgctact attcaagaat
     1921 cggccacaat caaggttctt tccttagttg tcctaccaga cagggcagca gctcaatcag
     1981 tgaatgtcct tcttacttct tgaggtgagc ttgtggtctc atgagatcaa aaaattattt
     2041 ttctaggtta agaaaagttt aagctttatg ctatac
//
LOCUS       DARYXS010000153         2045 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.154, whole genome shotgun sequence.
ACCESSION   DARYXS010000153 DARYXS010000000
VERSION     DARYXS010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2045
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.154"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(166..531)
                     /locus_tag="TV193_001899"
     CDS             complement(166..531)
                     /locus_tag="TV193_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEL1514051.1"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQASLSCKLSI"
     gene            complement(592..1638)
                     /locus_tag="TV193_001900"
     CDS             complement(592..1638)
                     /locus_tag="TV193_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001868451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1514052.1"
                     /translation="MTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYEPLHF
                     FLKSFLGRMAVPYFLICTAFFLRGRLREANREKQYFKQILKTYLLWSLIYLPYAYAFF
                     ESLRLPKHYLPLGLCLALSYFGMCYHLWYIPALWLGWVLVQLSLKTFGKKVTLIIVAG
                     LYLLGSMETYSHFLSSTPFEPLLTGYMHIFQTSRNGIFYTPAYLCAGCLLYDHFSSSL
                     FSQRYMRKAAVCLILLALESLLIYHHQGLDKNFFLLSALFTTFLFNASVRISLLSKYS
                     LAKLKKLSYYYFFLHPMFIECSLFLLRPYQLAPATKGKLVFLMTLLATHLCSEALMLL
                     VRSQAHAKAYLKRQ"
BASE COUNT          675 a          433 c          379 g          558 t
ORIGIN      
        1 gattttatca taatgaggct cgctatgttg ttttctctat cccaatcagg cactgctaga
       61 ttagacatct ttccagacaa caaaaatagc ctaaggtcag ctctctaatt agctgatctt
      121 aggctatttg agtgataata gatttgactg atagctgtaa gcctctcaga tgcttaattt
      181 acagctaagg gaggcttgtg ggcagtcatt tctttgctca aaatatgact gataatgatg
      241 ctttggcaca atgtctctat cctttagcaa taaaagagag tgatactgct gcagctcctc
      301 atcgcaatcc tcacaccatc ttcgctcatc ttccctccaa aaggtagcca ataagctttt
      361 ttgactgtgg tagctgggat agctcttttt catgcgctgc cattcttcct caaaataagc
      421 cagtgcagca ggccagctgt caaacgattt ctcctgaaca atatcgtctt gccaaccatc
      481 tataaaccac caaggctccc agtctccata catttcaatc acttgataca tgttctcatt
      541 tcctctattg cctattatag ccgaagaaag atatttttaa aaaacatctg ctcactgcct
      601 tttaagatag gccttggcat gagcttgaga acgtaccagc agcataaggg cctctgagca
      661 aagatgagta gctagcaggg tcatgagaaa gaccagtttc ccttttgtgg ccggggcaag
      721 ctggtagggc cttagcagaa atagcgaaca ttcgataaac attgggtgca agaaaaaata
      781 ataatagctt agctttttta atttagctaa agaatattta gacagaaggc tgatacggac
      841 actggcattg aataaaaagg tagtaaacag cgcagaaagc aagaagaaat ttttatccag
      901 accctgatga tggtaaataa gcaggctttc caaggccaat aagatcaggc aaacagccgc
      961 ctttctcata tacctctgag aaaaaagcga cgatgaaaag tgatcataga gcaagcagcc
     1021 cgcacaaaga taagcagggg tgtaaaaaat accattgcga cttgtttgaa aaatgtgcat
     1081 gtagcctgtc agcaaaggct caaaaggcgt cgagcttaaa aaatgagaat aggtttccat
     1141 actccctagt aaatacaagc ccgccactat gatgagcgtt accttcttac caaaggtctt
     1201 cagagaaagc tgaacaagca cccaccccag ccataaagca ggaatatacc acagatgata
     1261 gcacatccca aaataactaa gggctaaaca caagccaagg ggaagataat gcttaggcag
     1321 acgaagcgac tcaaaaaagg cataagcata agggaggtaa atcagagacc aaagcaaata
     1381 ggtttttagt atttgcttga agtactgctt ttcccgattc gcctctctaa ggcggcctct
     1441 tagaaaaaag gcggtacaaa tgagaaaata aggcaccgcc attcttccta aaaagctttt
     1501 caaaaagaaa tgcagcggct catactgaaa cagcctaccg ctatgaataa caataaccat
     1561 tatggcaaaa cagtattgta acaggcttac cacagaggta ttgaggctgt cagtgacttt
     1621 ctggctctct tttgtcatca attcaatcac tttcttttaa gagattaata tacgtataac
     1681 ttttagtatt tatcgcattt gtctctcatt ttgattaata ttgtttttat catagcgtaa
     1741 tataaccaat taatctaatg attttagcat aacaaaagga gctaaggcta gctcctgaac
     1801 atcacaaaag agcagacgaa cttcatctcc tctcgtgctt agatataagc cacccactac
     1861 agttaacatg gagccataaa acgaaggaat taactccttc gttttctttc aatttttctt
     1921 ggaatatttt tatagacttt tcttacggat atagtaagaa taactaccag caataatgac
     1981 ataattcaat aaaagacata attaatcaca acttgattgt ctttctaaca aatccattcc
     2041 ctgcc
//
LOCUS       DARYXS010000154         1998 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.155, whole genome shotgun sequence.
ACCESSION   DARYXS010000154 DARYXS010000000
VERSION     DARYXS010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1998
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.155"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..307)
                     /locus_tag="TV193_001901"
     CDS             complement(<1..307)
                     /locus_tag="TV193_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1514053.1"
                     /translation="MRWDYGKIYQAIRKSKGLTQEKICGDFLARSTLARIESGQVIPK
                     FDTMIFLLNQLNMTLEEFRYVCNTYHPSTRQDILNQFYNQVSAVNITELEKLRQKCFN
                     "
     gene            604..1176
                     /locus_tag="TV193_001902"
     CDS             604..1176
                     /locus_tag="TV193_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL1514054.1"
                     /translation="MKKRLAFILVAFGILGFSLGNEVLAADTAPASATMATDSDVSFY
                     NGELLKKYLVQSGDRLYFDYDKAIQDKVSDGVIDMGFLVETISEDYSQQTFTSRKYFK
                     AGWQLYGNYCGPGHNGNHFTLPVIDVLDQGCQNHDSCYRWGAGIGANCECNRQLVNYI
                     KVYRRWMPAHALGVADAIRVYFETVGAIGC"
     gene            1170..1460
                     /locus_tag="TV193_001903"
     CDS             1170..1460
                     /locus_tag="TV193_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514055.1"
                     /translation="MLTLKNIINRYYMYYVFLIVVIWIGMFFVRWDTTVAGVLLYPLI
                     MKQVFIVLGVVAMIMAIISRKIVLGIFGLLCCAAFWINLFLAFYLLPGLLGN"
BASE COUNT          612 a          261 c          395 g          730 t
ORIGIN      
        1 aattgaagca tttttgacgt aatttttcta attcagtaat atttacagct gatacctgat
       61 tataaaattg gtttaaaatg tcctgccttg tgctaggatg ataagtgttg cagacatatc
      121 taaactcttc cagtgtcata ttgagttggt ttaataaaaa aatcattgta tcaaatttag
      181 gaatgacttg tccgctttca atacgagcta gtgtagaacg agctaaaaag tctccacaga
      241 tcttttcttg tgttaatcct ttagattttc gtatagcttg ataaatttta ccgtaatccc
      301 aacgcataaa acacctctaa aatgttacta aatgctacaa aaaaataaaa tctacaatag
      361 tattttataa tagcatttag aaagagtaaa ggaggaaaat ttatgaggag acatctaaag
      421 gttgtattat tacttgcagc actattggca tttattgtaa atgagggtaa ttttccatgg
      481 tggccttggg gaccatagta cttaactgat tactgttatg ttgttgccat tagactatct
      541 agattaatca aagagtaaaa tacaagtagc ttagtgaaag acattttaag aggagaaaag
      601 catatgaaga aacgtttagc atttatatta gttgcttttg gtattttggg atttagttta
      661 ggaaatgaag ttttagctgc agatactgca cctgcaagtg caactatggc aacagatagt
      721 gatgtgagtt tttacaatgg agaactgttg aaaaaatatt tggtccaaag tggtgataga
      781 ttgtattttg attatgacaa agctattcaa gataaagttt ctgatggtgt aatagatatg
      841 ggattccttg ttgagacaat tagtgaggac tattcacaac aaacgtttac ctctcgaaag
      901 tatttcaagg caggatggca gctttatggt aattattgtg gacctggcca taacggaaat
      961 cattttactt tacctgttat tgatgtttta gatcaaggct gtcaaaatca tgacagttgt
     1021 tatcgatggg gagctgggat tggtgcaaat tgtgaatgca atcgtcagtt agtaaattac
     1081 attaaagtat atcgacggtg gatgccagct catgccttgg gggttgctga tgctattaga
     1141 gtatattttg aaacggtagg tgctattgga tgttaacctt aaaaaatatt atcaatcgat
     1201 actacatgta ttatgtattc cttattgttg tgatctggat tgggatgttt tttgtacgat
     1261 gggatactac tgtggctggt gtattactct atccactgat tatgaagcag gtatttatcg
     1321 tactaggagt agttgcgatg ataatggcca ttatttctag aaaaattgtt cttggaattt
     1381 ttggtttact atgctgtgct gctttttgga ttaatctttt cttagctttc tatctattac
     1441 ctggactttt gggaaattag cgattaaact gtttttgatg ttttgaagat gagaaacaga
     1501 ttgtttttct gtaaggcttc ctgttacttc tcaaatgctt tggagtatct ctttatcatt
     1561 tgttcactgt tgacaacgtt aaaaagatta ttccaaacat gggaattgct gcttcagggt
     1621 attccttgtt aatattggat tgattagttg ttatttatgc aaaatcctta gagcattgct
     1681 ttctcattct tggttcattt gaataaaatg taactaaaaa aactttgtaa tcaattcaaa
     1741 ttgtcacaag tataaaagta aaaaagcgac tttgttagtg atctgatatt cggaagtcct
     1801 atcattgctc gctttttgtt ttttgaggtt gatttttatt ccgaaattgt tgtgaataag
     1861 tgcaatttta agctaagaat tacctaaaat cttttgaaga ttactgctta gcttctaata
     1921 cctatttatc ggtgtgttga taattggaga gatagcggga ttgtcatatg aaataaattt
     1981 tagaaaattt aaacaagt
//
LOCUS       DARYXS010000155         1973 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.156, whole genome shotgun sequence.
ACCESSION   DARYXS010000155 DARYXS010000000
VERSION     DARYXS010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1973
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.156"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            162..1286
                     /locus_tag="TV193_001904"
     CDS             162..1286
                     /locus_tag="TV193_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEL1514056.1"
                     /translation="MAKKEMKFYLRKSAFGLASVSAALLVGAAAVSADSVESAGPVAV
                     AVTDSLDSEAAATKAEADLVAAKADLAAAEVAITAAKAEFDTAQADLATAEATIAELE
                     QKIPELEKKIQEAQEKLNYENRPSPKRVGSDDEDDTVARKLMSEKEALKAELQKTKEA
                     LDTAKRAYAGIEERKQVAATKLDAANKAFAGVEEKHAQAMAAFGAAFAAYKEAVKAEL
                     KAAGASDFYTKKIDSADTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPK
                     QDTNKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN"
     gene            complement(1448..1973)
                     /locus_tag="TV193_001905"
                     /pseudo
     CDS             complement(1448..1973)
                     /locus_tag="TV193_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515444.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
BASE COUNT          691 a          378 c          425 g          479 t
ORIGIN      
        1 tgctaaagta atggttgaca tataattgta aaaaaacaga aataaaaaaa aaacggttta
       61 atattgacct aattggcaat aacgtttaca ataaaggtat aattatctgc cgttgataat
      121 taggagacat catgtctaga taaaaacaaa aggggaataa aatggcaaaa aaagaaatga
      181 agttttacct tcgtaaatca gcctttgggc tagcttcagt atcagcagcc ctcttggttg
      241 gtgcggcagc tgtatcagca gattctgttg agtcagctgg gcctgtagca gttgctgtta
      301 cagatagttt agatagtgaa gccgcagcta caaaggcaga agctgatcta gttgctgcaa
      361 aagcagacct agcagcagca gaagtagcaa tcacagctgc aaaagctgaa tttgacaccg
      421 ctcaagcaga cctagctacc gctgaagcta ctatcgcaga gcttgagcaa aaaattcctg
      481 agttagagaa aaaaattcaa gaagctcagg aaaaactaaa ctatgaaaat cgaccatcac
      541 ctaaacgtgt gggcagtgat gatgaagatg acacagtagc tagaaagctt atgtcagaaa
      601 aggaagctct taaggctgag cttcaaaaga ctaaagaagc gctagataca gctaaaagag
      661 cttatgctgg catcgaagaa agaaaacaag tagcagcaac taagctagat gcagctaaca
      721 aggcttttgc tggagttgaa gaaaagcatg ctcaagcaat ggctgcattt ggagcagcat
      781 tcgcagcata caaggaagct gttaaggctg aattgaaggc agcaggtgct agcgacttct
      841 acaccaagaa gattgactct gccgacacag ttgacggtgt taagacactc agagaaatga
      901 tcttagactc aattgctaag ccagaggttg aaccagaggc taagcctgaa cctaagccag
      961 aaccaaaacc tgagccaaaa cctgagccaa aaccagaacc taagccagaa ccaaaacctg
     1021 agcctaagcc agagccaaaa ccagaaccta agcctgagcc taagccagaa ccaaaaccag
     1081 aacctaagcc aaaacctcaa cctaaaccag ctccagctcc aaaacctgaa gctaagaagg
     1141 aagagaagaa agcagcgcct aagcaagaca ccaacaaatt gccatcaaca ggtgaagcta
     1201 caaatccatt cttcaccgcg gcagctcttg cagttatggc aggtgcaggc gtggctgcag
     1261 tgtcaacaag acgcaaagaa aactaagcct tataccccag tggtaaagct tgagcgagaa
     1321 caatttgttc tcgctttttt agtgtcttaa aagcacctac agcaatcata ggtgcttaac
     1381 aagatatgtc taacgattgc tatcagctgt agagaataaa aaggagagac taagccttgc
     1441 tcacaagcta cttagaccga aggagcttta ggatttctat gatttgctga ggggagtcct
     1501 tacagccgca gctgatccac ttaatgatga tgacctcaat agaggcaatg tatagctcaa
     1561 aaacatattt ttgggtaact tcaggataat cttgtgattc tgcacaattc atgaggttgg
     1621 aataggaaat aatatcccta atataatgat taaaaatttt ataaatatta ggataataaa
     1681 ggattaagct ttgcatgacc tcctgattgt cagagaggta gtttaggatt tttaaggtaa
     1741 tagttgtatc aagtgatggg gattggtaaa tgatagaggt gatatcatct aggtaaacgc
     1801 cgatcatttc cctatctaag tccttcttag agttgaaata atgttaaaag gttgttcgac
     1861 tgatattaga agccttgcta atatctgata cagtaatact gtccttatcc ttgtattgta
     1921 gtagtcggca gtagctttta attatttttt tacaagtttg tttattttta tcc
//
LOCUS       DARYXS010000156         1911 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.157, whole genome shotgun sequence.
ACCESSION   DARYXS010000156 DARYXS010000000
VERSION     DARYXS010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1911
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.157"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            39..344
                     /locus_tag="TV193_001906"
     CDS             39..344
                     /locus_tag="TV193_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514057.1"
                     /translation="MLAVSTLSFGSAATARVVSAATAHPAPYPIIDEWNYGVSDNYGY
                     SNDYVKSPNNIGSKSSVTNLWGTVKDRDSQKYGWANSSATKSWNDVRLNTHWNYFTF"
     gene            411..>1911
                     /locus_tag="TV193_001907"
     CDS             411..>1911
                     /locus_tag="TV193_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1514058.1"
                     /translation="MKLKLCIVGFFFCLIAAIGLVSINDTQKPIPLPIDGAFSIQGKS
                     NLSNEEVYQTISDLSKEKKVTIYKPVVQNSGQLTYIKFDNTNHEQLKSAPITGMYYTL
                     GKLDSNSLKPLTSTGLQVIYLAYPWQIGGMIQFTGPLRLLLMISIYLTLLVVLFVVRA
                     RQIKEGVIRRSLGLPVHDLRRDYFMSFTFELVMAALLMISYSSFLGSGFFTYSSKLFF
                     SMLLTNLIIFQIIDIITFVLFWLTIKVEKPIEIIKNKAKNSLIFIVWLAVISIIIVVS
                     GVFLRETKASQSKINMQIKHLKPWSAVKDWKRPEFLGIENESVTNGEEANDSGAKYVE
                     IAKALKKLDFIYIKSSSAYVPEYMAASDVTEDFSKQLKSDGITHPEVNKELVYINQTG
                     AKVQNKVNGTNYQSLDNKIATIYIPHKFKENKASIENTVVAEQFTGTNYTKDDLTVQV
                     IPDGQEFFYFNENGSSVPENKDNLPLESVTDSKDNIVVVLDTDKMIENND"
BASE COUNT          667 a          277 c          351 g          616 t
ORIGIN      
        1 gagaactaat atgaaaaatt ggtgacaaaa cattagtttt gcttgctgta agcactttaa
       61 gttttggatc tgctgctaca gctagagttg ttagtgcagc aacagcgcat ccagctccat
      121 atccaattat tgatgaatgg aattatggtg taagtgataa ctatggttat tctaatgact
      181 atgttaagtc tccaaataat attggttcaa aatcttcagt aactaatcta tggggaacag
      241 ttaaggatag agattctcaa aaatatggat gggcaaactc aagcgcaaca aaaagctgga
      301 atgatgttcg attaaataca cattggaatt actttacatt ttaaaaatgg tttatgaaag
      361 ctaaaggccc aataatgcta tagggccttt tatgatatag gtaggtgctt atgaaattaa
      421 aattatgcat tgttggattc ttcttttgtt taattgctgc cattggtctg gttagtatta
      481 atgatactca aaaaccaata cctttaccaa ttgatggtgc cttctccatt caagggaaaa
      541 gcaatctttc taatgaagaa gtgtatcaaa cgattagtga cctatcaaaa gagaaaaaag
      601 ttaccattta caaaccggta gttcaaaatt cggggcagtt gacttatatc aagtttgata
      661 atactaatca tgaacaatta aagtctgcac caatcacagg gatgtattat accctaggga
      721 aattagattc aaatagttta aaaccgctca catctacagg tcttcaagtc atatatctgg
      781 cttacccttg gcagataggg ggaatgatac aatttactgg tccgttgaga ttattgctaa
      841 tgatttcaat ttacttaacc ttattagttg ttctatttgt tgttagagcg agacagatta
      901 aagaaggagt gataagacgt tctttaggat tacctgtaca cgacctaaga agagattatt
      961 tcatgtcatt tacttttgaa ctggttatgg ccgctttatt gatgatttct tatagttctt
     1021 ttttgggtag tggttttttc acctacagtt ccaagttatt tttttctatg cttttaacta
     1081 atttgatcat atttcaaatc attgacatca tcacctttgt tctattttgg ctaactatta
     1141 aggttgaaaa acctattgaa attataaaaa ataaggccaa aaatagcctc atttttatcg
     1201 tatggcttgc ggttatttct atcataatag ttgtttcagg agtcttttta cgggaaacaa
     1261 aggctagtca atcaaagata aacatgcaga taaagcattt aaaaccatgg agtgcagtaa
     1321 aagattggaa aagaccagag tttttgggta ttgaaaatga atctgttact aatggagaag
     1381 aagcaaatga ctcaggagct aagtacgtag agattgctaa agccttaaaa aaactggatt
     1441 ttatatatat caaatcatct tcagcctatg ttccagaata tatggcagct tctgatgtta
     1501 cagaagattt ttctaagcaa ttaaaaagtg atggaataac gcatccagaa gttaataagg
     1561 aactggttta tattaatcaa acaggtgcta aggtacaaaa taaagttaat ggaacgaact
     1621 atcaatcatt agataataaa atagcaacca tctatattcc tcataaattt aaagagaata
     1681 aggcatcaat cgagaataca gttgtagcag aacaatttac tggtacaaac tatacaaaag
     1741 atgaccttac ggtgcaagtc attcctgatg ggcaagaatt tttctatttc aatgaaaatg
     1801 gtagtagtgt tcctgaaaat aaagataatc tacctttgga aagtgtgaca gatagtaagg
     1861 ataatatagt cgttgtgcta gatactgata aaatgataga aaataacgat t
//
LOCUS       DARYXS010000157         1874 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.158, whole genome shotgun sequence.
ACCESSION   DARYXS010000157 DARYXS010000000
VERSION     DARYXS010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1874
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.158"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            396..854
                     /locus_tag="TV193_001908"
     CDS             396..854
                     /locus_tag="TV193_001908"
                     /inference="COORDINATES: protein motif:HMM:NF025561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HEL1514059.1"
                     /translation="MKETVVLAKKEYILENEIYTPIVKESPFERQGGTYRLEKMEDGA
                     EVLVPNMKMPEKINASKLNRFGKERLKYLKEEKQEEYQIMLMEETLMDHLIDIQEQVE
                     DFLNIEEPRMKEAWKMTTEMQDQDFLKYTGLKKNLDMTLTKMAMEQIIWV"
     gene            740..>1874
                     /locus_tag="TV193_001909"
     CDS             740..>1874
                     /locus_tag="TV193_001909"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1514060.1"
                     /translation="MENDHRNAGSGLSEIHRTEEELGYDTNKNGYGTDHLGIDEYRKE
                     NIQKIEQNHVENEEKEVERTSFSFAQNVGVQGRFELPMQQEEIGAVLIHGGNEDNLHL
                     KVLAEYSKEKSMEELADFLQKTFQGGNGYELNGNKVCAWYEMDGIHLSNDVSSRENPM
                     QILPWKDAAIRIGELIDYGKYSTNVEVAEAFSFERAELSEKLWFLKGDLSDEVKNQFL
                     PILNEKQRNGYPEKTEYLTKKLEDKEFRVNLKEEYIEFFKAYKENSNVLRFHNHDLDD
                     ISKRLDDLELPRKEFTSTLIELPAIQGFITEDEIDRYLSSGSNVSGGKERIYNFFREA
                     HTTEERANFLKDEYGTGGQTHALSRARGSSEWHDAKGIKLEKEN"
BASE COUNT          762 a          213 c          426 g          473 t
ORIGIN      
        1 taaggtactt aattctttaa gtgatgaaac tttaaaggaa aataagaaag tacaaattct
       61 tcattttttg gaagaatctg caaaagtatc ggtatatgag agaatgggag ttgcattttc
      121 cggtgatata gaaaaattag agatgctttc aaatgtttca agtatgcagg atattgacag
      181 attacttttc tttacttcaa acaatgtaaa aagaatactt atggatataa gtagagaaat
      241 ttcaaaagtg gaagaaagag aaaaaatttc agaaattcaa aaaagggagc agacaaatag
      301 tattgcggag cgttatacta atgttacaga tgaaattaac ggaaataccg aaattataga
      361 aaatgaaaaa gaaagaaatg aaggaggttt ggaagatgaa agaaaccgta gtattggcga
      421 agaaggagta catcctagaa aacgagattt atacaccgat cgtaaaagag agtccattcg
      481 agagacaggg agggacttac agattggaga aaatggagga tggagcggaa gtattagttc
      541 cgaatatgaa aatgccggag aaaataaacg caagcaaact gaaccgattt ggcaaggaga
      601 gactgaaata tctcaaagag gagaaacaag aggaatatca gattatgctg atggaagaaa
      661 ctttaatgga tcatttgata gatattcagg aacaagtgga ggatttcctg aatatagaag
      721 agccgaggat gaaagaagct tggaaaatga ccacagaaat gcaggatcag gactttctga
      781 aatacacagg actgaagaag aacttggata tgacactaac aaaaatggct atggaacaga
      841 tcatttgggt atagatgagt atcgtaaaga aaatatacag aagatagaac aaaatcatgt
      901 agaaaatgag gaaaaagaag tcgagaggac ttctttttct tttgctcaaa atgtaggagt
      961 tcaaggaaga tttgaattac caatgcagca agaagagatt ggtgctgttt taattcatgg
     1021 aggaaatgag gataatttac atttaaaggt tttagccgaa tattctaaag aaaaaagcat
     1081 ggaagaatta gctgattttc ttcaaaaaac ttttcaagga ggaaatggat atgaactaaa
     1141 tggaaataag gtttgtgctt ggtatgaaat ggacgggata catttatcca atgatgtttc
     1201 ctcaagagaa aatcctatgc agattttacc atggaaagat gcagcaatac gcataggaga
     1261 attgattgat tatggaaaat acagtacaaa tgtggaggta gcagaagcct tttcttttga
     1321 aagagcagaa ctttctgaaa agctgtggtt tttaaaagga gatctaagtg atgaggtaaa
     1381 aaatcagttt ttgccaattc taaatgaaaa acaaagaaac ggatatcctg aaaaaacaga
     1441 gtatcttaca aaaaaattgg aagataaaga gtttagagtg aacttaaaag aggagtatat
     1501 agagtttttt aaggcgtata aggagaactc gaatgtttta agatttcata atcatgattt
     1561 agatgatata tcaaaacgat tagatgattt ggaactgcca agaaaagaat ttacctcaac
     1621 acttatagaa ttaccagcaa tacagggatt tatcacagaa gatgaaattg atagatattt
     1681 aagcagcggt agcaatgtat ccggcggaaa agaaagaata tataactttt ttagggaagc
     1741 ccatactacc gaagaacgag caaatttttt aaaagacgag tacggaacag gaggacagac
     1801 tcatgcttta tcaagggcaa gaggaagtag tgagtggcac gatgctaagg ggataaaact
     1861 tgaaaaagaa aatt
//
LOCUS       DARYXS010000158         1872 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.159, whole genome shotgun sequence.
ACCESSION   DARYXS010000158 DARYXS010000000
VERSION     DARYXS010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1872
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.159"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..177
                     /locus_tag="TV193_001910"
     CDS             <1..177
                     /locus_tag="TV193_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1514061.1"
                     /translation="EFKQAVDNGYITGDVVMIVRKNGQILDYVLPHESVRAWEVVTVE
                     AVADVLAELYNKEF"
     gene            192..455
                     /locus_tag="TV193_001911"
     CDS             192..455
                     /locus_tag="TV193_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1514062.1"
                     /translation="MLLVLLIISVLMLLFVPNLSKQKDKVTDTGNAAVVKLVENQAEL
                     YELSHGEKPSLKQLQEDGSISDKQQKAYQDYYAKHKDEAKKLN"
     gene            433..858
                     /locus_tag="TV193_001912"
     CDS             433..858
                     /locus_tag="TV193_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEL1514063.1"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLYLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            815..1105
                     /locus_tag="TV193_001913"
     CDS             815..1105
                     /locus_tag="TV193_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1514064.1"
                     /translation="MVIIKKQVKAYIALEGLIATGLILVIVTLILSALRYSQQELSAC
                     RQKQELLNTAVMAMQTKQRALSLNGCHIKLLSHQKGIAIVEKDQTIIRIERQ"
     gene            1092..1526
                     /locus_tag="TV193_001914"
     CDS             1092..1526
                     /locus_tag="TV193_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1514065.1"
                     /translation="MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMANERYLAA
                     NDQNNWLLFSQQLRAELSGTTLQGVRNNRLYVEKDKKALSFGQVKGHDFRKAASNGQG
                     YQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG"
     gene            1504..1866
                     /locus_tag="TV193_001915"
     CDS             1504..1866
                     /locus_tag="TV193_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1514066.1"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHQEYQAQM
                     DYAKAQLIAEMVYQEQPSGDGQIAFNCGQVSYKSHKQRFIIEIKLPHQQLYQFSYPEV
                     QQASQTSKKQSELKQSLP"
BASE COUNT          562 a          343 c          436 g          531 t
ORIGIN      
        1 gagtttaagc aggcagttga taacggttat atcacaggag acgtggtcat gatcgtgcgt
       61 aaaaacggac agattttgga ttatgtgttg ccgcatgagt ctgtgagggc ttgggaagtg
      121 gtgacagtcg aggcagtagc tgatgtttta gctgaattgt ataacaaaga attttagtat
      181 cttttattga aatgcttctg gttttgttaa tcattagtgt tttgatgctg ttatttgttc
      241 caaatttaag taaacaaaag gataaggtga cagacacagg caatgctgcg gtggtaaagc
      301 tggttgaaaa tcaggcagag ctttatgaat tatcacatgg ggaaaagcca agcctgaagc
      361 agctgcaaga ggatggaagt atcagtgaca agcagcaaaa ggcttatcag gattattatg
      421 caaagcataa agatgaagct aagaagctca attaaagctt ttaccctctt agagggttta
      481 ctgacacttt ttctgattag ctttatgctg ctgtacttgt cactaccggt atcagatagc
      541 tatgctaggg ttgaggagca tctctttttc atgcgctttg aacaggctta taggcaccta
      601 cagaagctat cgatattacg tcaaaaagag catgtgctgg tcttaaagcc acattatatt
      661 aaggccgaag aagctatttt gcctctacca aagcaggtca agctaaaatc tacccagacc
      721 ttaaccattg ataaactggg cggcaaccat tcgctggcaa gagttgtctt tgaaaataga
      781 gatcggcaga ttacttatca attttattta gggagtggta attatcaaaa aacaagtcaa
      841 agcctacatc gctcttgaag gcttgatagc gacaggactt attcttgtta ttgtaacact
      901 gatactgtca gccctgcgtt atagccaaca ggagctgtcg gcctgtcgcc aaaagcaaga
      961 gctgttgaat acagctgtga tggctatgca gacaaaacaa agggcattaa gccttaatgg
     1021 ttgtcatatt aagctattat cacatcagaa gggtatcgct attgttgaaa aagaccaaac
     1081 gattattagg attgaaagac agtaggctaa aggctttcac cttgatagag tgccttattg
     1141 ccttgcttgt catctcaggc tctttattag tttatcaggc cttaaccaag agccttatgg
     1201 caaatgagag gtatctagca gcaaatgatc agaacaactg gcttttgttt tcccagcaat
     1261 tgcgagcaga gctttcaggt actaccctac agggtgtccg caataatagg ctatatgttg
     1321 aaaaggacaa gaaggctttg tcctttggac aggtcaaggg ccatgatttt agaaaagcag
     1381 ctagcaatgg tcaaggctat cagcccatgc tgtttggctt gtcaagtagc caaataacag
     1441 cagtaggtca gcaggtgacc atcaagctga aatggcaaag cggcttagaa aggaccttta
     1501 tttatgcatt tcaagagaag ggttaaggca ggagtgcttt tgtatgcttt gctgatggca
     1561 tcggtctttt tattactgtt acaggcttat cttagtcata ttagccagct acatcaggaa
     1621 tatcaggctc agatggacta cgcaaaggct cagctaatag cagaaatggt ttatcaggag
     1681 cagccttctg gcgatggtca gattgccttt aattgtggtc aggttagcta taagtcgcat
     1741 aagcagcgtt ttataattga gatcaaatta ccacatcagc agctatatca atttagctat
     1801 cctgaagttc agcaggcctc tcagacttct aaaaagcagt ctgagcttaa gcaatcactc
     1861 ccataactaa gg
//
LOCUS       DARYXS010000159         1847 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.160, whole genome shotgun sequence.
ACCESSION   DARYXS010000159 DARYXS010000000
VERSION     DARYXS010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1847
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.160"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(32..664)
                     /locus_tag="TV193_001916"
                     /pseudo
     CDS             complement(32..664)
                     /locus_tag="TV193_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(666..1433)
                     /locus_tag="TV193_001917"
     CDS             complement(666..1433)
                     /locus_tag="TV193_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEL1514067.1"
                     /translation="MEQKLNHLAVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     GRQQMIATVAYLESGQDRFVYNTTPISYQQFLKDPIIIVVTPQSTGPQSVMFWFDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQSGYQNYITLLNNIQRERWIMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIVIKRIAGLRFLEIHRNYLLAQLGVFLLGFVASVFLQVE
                     IVIAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(1715..1847)
                     /locus_tag="TV193_001918"
                     /pseudo
     CDS             complement(1715..1847)
                     /locus_tag="TV193_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
BASE COUNT          547 a          377 c          344 g          579 t
ORIGIN      
        1 tagctaaaaa taccaaaaaa attatgaatc attatcgcaa actatccata gtgatcattt
       61 catcagccat ttcccatatt gctggattat gagttgctac gatgattaat ctgttagcgt
      121 cacgaagaga cagtacaatc tccataatca acttggacgt ggttggatct attgaagccg
      181 ttggttcatc tgccaaaata aatggcggat tttttaagat gatctttgct aaggcaactc
      241 gttgtgacta acccccagat agctcaaaaa tgcgtttatc taggttcaga taggataaac
      301 ctacacgttc taaggcctgt ttctgtctca tcgtttgctc agatttattc aatttttgac
      361 caatgagacc aagtttgagg ttttcttcaa tcgtttgatt ttcaatcaaa ccaaaatttt
      421 ggaataggta acccaattca tgacggaaaa aatcactaga tttatagctg gctaagtctt
      481 tgtctcggta aaaaatagtc ccatgataag gttctaattt ccccatcatg ttcatcaagg
      541 ttgttttccc gctaccgctt gaaccaatca aagcatagac ttttccaacc tcaaatgtca
      601 ttgaaagatt agaaaatagc tctcgttctc caaaagattt actcacttgt ttaagttcaa
      661 tcatgttaac ctcctttcaa aacaagcatg gacatcttgt tttctttctg catttgaaca
      721 tgtaattgta aaagagatag gccagtgaag agcaacaata ctaagaaagc aatcactatc
      781 tctacttgaa ggaatacact cgcaacaaat ccgagtaaaa agacacccaa ttgagccagg
      841 aggtaattcc gatggatttc taaaaatctt agtccagcaa tacgtttgat gacaatggca
      901 cgtctaaatt cttcaaagta gagcctattc atggtgttaa acaacaagat tgaggttgct
      961 atcccaagca cagctcccgc aagcattatc caacgttccc tctggatatt attcaacaat
     1021 gtgatgtagt tctggtatcc tgattgcatt tctgagaccc aattttcaat gccctgtctc
     1081 tggataagct cctgggcatc ggacaactga ttaaagagga cataattctg taccgcgtca
     1141 aaccaaaaca tgacggactg aggtccagtt gactggggtg ttacgacaat gataatcgga
     1201 tctttcagaa actgttgata ggaaataggt gtcgtattat acacaaaacg gtcttggcct
     1261 gattccaaat aagccaccgt cgcaatcatt tgctgtcgac catcttgact agacatgcga
     1321 ctagttaagt cgtcttcaaa aacagatttg taatgttctt cctctgaacg gagatgctca
     1381 ggcaagagca agacaaattc ccctactgcg aggtgattca gtttttgttc aatagccgta
     1441 tctacaggga tgttttgacg ctccaagtat tgcggtgtga caataaggac attgccattt
     1501 gggctgtaat cttgccattc tgtagaagtt gtcaagtttt tggaaaagtc ttagcctttg
     1561 ttatcaatac ttgagtagca cctatgtttt tcagattagc ttgctcttgt aactgttctg
     1621 agctattaaa tgctgtcatt tcaacggtga tattttcagt tgattctgcc tgcttgttat
     1681 cttcttttgt tggagattct ggacgtttct caaaataaaa ataattataa agctgttgag
     1741 ccgttactcc tccaccagcc cagccagcaa caggttgacc attcttcaga tatagtattg
     1801 ttggtgttcc tgggattcca actgttttaa ataaaaactc ctgagct
//
LOCUS       DARYXS010000160         1826 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.161, whole genome shotgun sequence.
ACCESSION   DARYXS010000160 DARYXS010000000
VERSION     DARYXS010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1826
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.161"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(207..1721)
                     /locus_tag="TV193_001919"
     CDS             complement(207..1721)
                     /locus_tag="TV193_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1514068.1"
                     /translation="MLDYYLERDIVERKLILAVLLTEKEITLDSLCSQTSITPRKAKE
                     YLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFHSIYASSDTLKMLKFLLTDNYRT
                     KCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDIDDYRVIGDEYRIRYLIAMLHKEY
                     GFAVYEMTPKDMEIIHAFIFLTPTRLKPTVFLDKKFYLFDILLMLSWKRQNYDVSLPQ
                     LTLFDRLKELSIFEQISCYAKQEIETRTQVVFNSGDLDYLYLVYLTVDSSFLMHYWND
                     KQLRLVYNILEEDPLYKELVNRLEMLFGRQLHLRDQMYFLLPFFRRCLFQLHDLISFQ
                     DYYSKRYQGSQLLLEKVEEQIKDWLMVSYQSETLSPGHLHFMCLHLEQMLELSLPPVE
                     VIIVENKRALGDVLSYFVISSIPSYKVNITRINMLTDSLENYEQAPDFVITSDNILPF
                     LEEQQVFPDKSVLIGMSMDYIKEQGKTVVKSILNFHRKHYEQLLEQLLIGDRVE"
BASE COUNT          633 a          375 c          295 g          523 t
ORIGIN      
        1 aaatccactt gaaaggctta tcacaagtgg atttttcaga aatattgtac caaataggca
       61 cgagctattg attgctgcta tttagcatag gtgttatcac gatcagcagt aagccaatca
      121 aaacaggtat cgctaaagca aatcctcaca aaaaatggtc caaagaaaaa cctagcagcc
      181 ttataccact tgcttagcaa aaaaacttac tctaccctat ctccaatcaa gagctgctct
      241 aaaagctgct cgtaatgctt acgatgaaag ttcagaattg attttaccac tgtttttccc
      301 tgctccttaa tgtaatccat gctcatacca attaagacgc tcttatctgg aaatacctgc
      361 tgctcctcaa gaaaaggcaa aatattatca ctcgtaatca caaaatcagg agcctgctca
      421 taattttcca gactatctgt tagcatgttg atacgagtaa tattaacctt ataagaagga
      481 atacttgaga taacaaagta agacaagaca tcacctaatg ctctcttgtt ttcaacgatg
      541 atgacctcta caggcggcaa ggacagctca agcatctgct ccaaatgaag gcacataaaa
      601 tgcaggtgcc ctggtgagag cgtttctgac tggtagctaa ccatcagcca gtccttgatt
      661 tgctcctcaa ccttttctag cagcagctga ctgccttgat acctctttga atagtaatcc
      721 tgaaagctaa tcaaatcatg caattgaaag agacatcttc tgaaaaaggg aagcaaaaaa
      781 tacatctgat cccttaaatg aagctgacga ccaaacaaca tttccaagcg attaacaagc
      841 tccttataca gcggatcttc ttctaagata ttgtagacaa gacgtaattg cttgtcattc
      901 caataatgca taagaaaaga actatcaact gtaagataaa ccaagtaaag ataatctaag
      961 tcaccagaat taaacacaac ctgagtacgt gtctcaattt cttgcttagc atagcaactg
     1021 atttgctcaa aaatagataa ttcttttaaa cgatcaaata aagtaagctg tggtaaggat
     1081 acatcataat tctgcctctt ccaagacagc atgagtaaaa tatcaaaaag ataaaatttc
     1141 ttgtccaaga aaacagtggg ctttaaccgc gtaggggtta aaaaaataaa ggcatgaata
     1201 atttccatat ccttaggtgt catctcataa acagcaaacc catactcctt atgaagcatg
     1261 gcaattaagt agcgaatccg gtactcatcc cctataaccc ggtaatcatc gatatccaaa
     1321 tgaatggatt gcaggtagcc ctttagctta ttgacaagat gataggcctt tgatttggaa
     1381 ataaactgtc ttctgatgaa agttgtcaga cactttgtcc tgtaattatc cgtcaacaga
     1441 aacttcaaca ttttaagcgt atcagatgat gcataaatac tgtgaaaata cttctccttg
     1501 ttattaggat caaactcaca ggtaatgcct gacttcaata cagtaataga caggtctttg
     1561 tcaaatagtg cattaatctg attaaggtat tccttagcct ttcgaggggt tattgacgtc
     1621 tgcgagcaca atgaatcaag tgtaatctct ttttctgtca ataagacagc caatattagt
     1681 tttcgctcaa caatatctct ttctaaatag taatctaaca aaataatctc tctccttatt
     1741 agtttgtatg accatataca ttttagttga taggatttaa aagtcaacta aaaaaaatac
     1801 acaaaaaata acgactgctt cctttc
//
LOCUS       DARYXS010000161         1814 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.162, whole genome shotgun sequence.
ACCESSION   DARYXS010000161 DARYXS010000000
VERSION     DARYXS010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1814
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.162"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(40..588)
                     /gene="raiA"
                     /locus_tag="TV193_001920"
     CDS             complement(40..588)
                     /gene="raiA"
                     /locus_tag="TV193_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEL1514069.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNL
                     KVYREKTAKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KMSTSQVFTSEFEAEKAEETPEIKVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDA
                     EDGATNVLYRREDGDLGLIEAK"
     gene            complement(664..1290)
                     /locus_tag="TV193_001921"
     CDS             complement(664..1290)
                     /locus_tag="TV193_001921"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEL1514070.1"
                     /translation="MSITAILLLSPNKDLMCDACQRHFCRITQPTCSNCYQYRHEGAC
                     QDCIAWKRQGYQVDHQSLYQYNTAMKDYFSRYKFQGDYVLRSLFAQELAKHIKKYYKA
                     YTLVPVPVSKQRYDERGFNQVTAILEYANLAYLDLFERIDDTRQSSKTKKERLQLNNR
                     YRLKKGAALPPKILLIDDIYTTGSTIMSLRQELVRHGCQDIKSLSIAR"
     gene            complement(1473..1658)
                     /locus_tag="TV193_001922"
     CDS             complement(1473..1658)
                     /locus_tag="TV193_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1514071.1"
                     /translation="MLTYEEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPGEEVQPWE
                     VVTVEAVADILNELQII"
BASE COUNT          500 a          392 c          312 g          610 t
ORIGIN      
        1 gcaaaaaaac aagaggtgag atgcctcttg tttttcaaat tattttgctt cgataagtcc
       61 taagtcacca tcctcacgac gataaagaac atttgttgct ccgtcctcag catctgtata
      121 gatgaagaaa tcatgcccta gaagttccat ctgcaagcga gcttcctcaa cgtccattgg
      181 ctttagagtc acatttttcg tgcggaccac tttgatttct ggagtttctt cagctttttc
      241 tgcttcaaat tcactagtaa acacttgact agttgacatt ttttcacgat gctttttggc
      301 aatttttgtt ttattttttc taatttgacg ttcgatttta tcaacgacta aatcaataga
      361 accatacata tcctgtgaaa cgtcttctgc acgaagtgtc actgaaccaa gcggaatagt
      421 gacttcaacc tttgcagtct tttcacgata aacctttaaa ttaacacgcg catctatttc
      481 ttgctcttca acaaaatatt tttcaatctt agtaagcttt gattctacat aatcgcgaat
      541 agcctctgtc acttcgatgt tttctccacg aatactgaat ttaatcataa gagtacctct
      601 ttcttgcgtt taaaacgctt tctttagttc tactatagcc gttttcatga aaatttgcaa
      661 gttttatcgt gcaattgaga gacttttgat gtcctgacag ccatgcctga caagctcctg
      721 ccttagactc attatggtgc taccggttgt atagatatcg tcaattaata agattttcgg
      781 tggaagagct gctccctttt tgagtcgata gcggttattt agctgcaggc gttctttttt
      841 cgttttgctt gattgtctag tatcgtcgat tcgctcaaat aggtcaagat aggctaggtt
      901 ggcatattct aaaatagctg ttacttgatt aaagcccctt tcatcatacc tttgcttgct
      961 aacaggcaca ggaaccaaag tataggcttt ataatacttt ttaatgtgct tagctagctc
     1021 ctgcgcaaaa agactgcgta aaacataatc tccttgaaat ttgtaacggc tgaaataatc
     1081 cttcattgcg gtgttgtatt ggtaaaggct ctgatgatca acctgatagc cttgcctttt
     1141 ccaggcaata caatcctggc aggcgccctc atgacgatac tggtagcaat tagagcaggt
     1201 tggctgagta atcctacaaa aatgacgctg acaggcatca cacataagat ccttattagg
     1261 acttaacaac agaattgctg tgatagacaa gctatcttta ctatttattg tggcagagta
     1321 gacagttcat tttgataccc tttttgattc atgtccttta tctcccgcac tgccttgagc
     1381 atagcctggc taataccatc atgaaaaaat agcacctgtc cttcaggtct ttccaaagag
     1441 cgcccaacgc gacctgaaat ttgaattagc ggtcaaataa tttgtaattc gtttaaaata
     1501 tcagcaactg cctcgactgt caccacttcc caaggctgca cttcctcccc tggcaacaca
     1561 taatcaaata tctgtccgtt tttacgcacg atcatgacca cgtctcctgt gatatatcca
     1621 tgatcaatag cttgcttaaa ttcctcgtat gttagcataa attacctcct tatcttatta
     1681 ttcgtaaaaa tctggtattg gtatattgga cacatttata tgtaccgaac aaaaaaacgc
     1741 cctcaattaa gagggtattc cttggtttct tgatactaac taattttctt tgtttgtgaa
     1801 tagatagaca tcaa
//
LOCUS       DARYXS010000162         1754 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.163, whole genome shotgun sequence.
ACCESSION   DARYXS010000162 DARYXS010000000
VERSION     DARYXS010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1754
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.163"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..>1754
                     /locus_tag="TV193_001923"
     CDS             <1..>1754
                     /locus_tag="TV193_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HEL1514072.1"
                     /translation="SHSEYNGVQVQRDISKKQGTSVYIAPVVFACNIDYPLETEFSRK
                     NLGKVSYMISQTPGVWLDFQTYIVDGDLILCWDSVDELFPTGMLEDMMDSLYELIISL
                     TQKEEWEKKVDVLPEKQKSIRMQDVEGILPLQYPSETLYDGFLRNVKLNPDRVAIIDS
                     ETKEEITYHKLYEISLKVADCLGKNGVKKGDYVGITLPRGSRQLYAIFGILFTGAAYV
                     SIGIAQPNDRRTKIYDQIGIKCIISDEKTVIDCKLNKNEVKIIDLDVAMANVAKLKQP
                     VEISPYDSAYIIMTSGTTGVPKGVEIMHTSAVNTCIDLNEKYNVNAEDTILMVSAIDF
                     DLSVYDIFGILHAGGTVITTSEDNYRNPDEWLNLVDEYKVTIWDSVPILFDMIVTMAE
                     GKNRNLPFRIVMLSGDWIAINLPERFYNISENINSIVVAMGGATEASIWSNHLNVPRK
                     IPKDWISIPYGRPLKNQVYRVVDEFGRICPNYVKGELLIGGVGVAKCYHGDEELTNKK
                     YFEQDGMRWYRTGDNGRTWNDGIIEFLGRKDTQVKVKGHRIELGEIENALIVFENIKK
                     AIALIVKDGNVNKLVGFA"
BASE COUNT          626 a          193 c          383 g          552 t
ORIGIN      
        1 tctcacagtg agtataacgg agtgcaggtt caaagagata tatcaaaaaa acaaggtaca
       61 agtgtgtata tagcacctgt ggtttttgcg tgtaatatag attatccatt ggaaactgaa
      121 ttttcaagaa aaaatttagg gaaagtatct tatatgattt ctcaaacacc aggagtttgg
      181 cttgattttc aaacatatat tgtagatgga gatttaattc tttgctggga tagcgtggat
      241 gaactttttc caacaggaat gttagaagac atgatggatt ctttatatga attgatcata
      301 tctttaacac agaaggaaga atgggaaaag aaagtagatg ttttacctga aaagcaaaag
      361 tctattagaa tgcaggatgt tgagggaatt ttaccacttc aatatcctag cgaaacgtta
      421 tatgacggat ttctcagaaa tgtaaaactc aatccagata gagttgcgat tatagattct
      481 gaaacgaagg aagagataac atatcataaa ctttatgaaa tctctttaaa agttgcggat
      541 tgtttaggta aaaatggtgt taaaaaggga gattatgtag gaataacact tccaagaggt
      601 agcagacaac tttatgctat ttttgggatt ttatttaccg gtgcagcata tgtatcaatt
      661 ggtattgctc agccaaatga tagaagaact aaaatttatg atcaaatcgg aataaagtgc
      721 attataagtg atgaaaagac agtgatagat tgtaaattaa ataaaaatga agttaaaatt
      781 attgatttgg atgtagctat ggcaaatgtg gctaaattaa agcaacctgt tgaaattagc
      841 ccttatgata gtgcgtatat tattatgacg tctggaacaa caggtgttcc taagggtgtt
      901 gagattatgc atacaagtgc cgttaatact tgcattgatt taaatgaaaa atacaatgta
      961 aatgctgaag atacaatact gatggtgtcg gcaatagact ttgatttgtc ggtttatgat
     1021 atttttggaa tacttcatgc tggaggaacg gttattacaa caagtgaaga taattataga
     1081 aatcctgatg aatggttaaa tttagtcgat gaatataagg ttacaatatg ggattctgtg
     1141 ccgattttgt ttgatatgat tgttactatg gctgaaggta aaaatagaaa cttacctttt
     1201 agaattgtga tgctttcagg ggattggatt gctataaatt taccagaaag attctataat
     1261 attagtgaaa atataaattc tattgttgtc gctatgggtg gagccacaga agcatctatt
     1321 tggtcaaacc atttgaatgt accaagaaaa ataccgaaag attggatttc cattccatat
     1381 ggtagacctt tgaaaaatca agtgtataga gttgtggatg aatttggtag gatctgccct
     1441 aattatgtta aaggtgaact tcttatcggt ggagttggtg ttgctaaatg ttatcatggt
     1501 gacgaagaat taacgaataa aaagtacttc gaacaagatg ggatgaggtg gtatagaact
     1561 ggagataatg gtagaacatg gaatgatggg attattgagt ttcttggaag aaaagatact
     1621 caggtaaaag ttaaaggaca tagaatagaa cttggagaaa tagagaatgc tttaattgta
     1681 tttgaaaata taaaaaaagc gatcgcttta attgttaaag atggaaatgt taataaactt
     1741 gtaggatttg cgga
//
LOCUS       DARYXS010000163         1723 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.164, whole genome shotgun sequence.
ACCESSION   DARYXS010000163 DARYXS010000000
VERSION     DARYXS010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1723
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.164"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            1..1636
                     /locus_tag="TV193_001924"
                     /pseudo
     CDS             1..1636
                     /locus_tag="TV193_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
BASE COUNT          699 a          205 c          378 g          441 t
ORIGIN      
        1 tgtaaaagac acattttcta aggaaagaat gaaatcagaa aaccagaaga aatatgtgag
       61 gagcaacttt gatgatgaag agttcacaag aaataaggat acgaaaaata atttatttca
      121 ggacgtaaat aataaaagaa aaactaccga taaaaattca tcacgaaaaa gaaaaggaaa
      181 atttgaaaat aaggaaaaga aaatatccaa gttacagcag aaaaagcaaa gacaagagca
      241 aaaactgaaa aataagggaa ttgacgggaa aagtcaaagt gctaaaagtg cagtaatagc
      301 aacgggtatg gcaaagaggt atttggaaag tggaaaagag gacaatgccg gagtaggtac
      361 tgcttataag gttacagatc aggtcgaaaa tatttcaagg aaaatatatt atcatggaaa
      421 aaagaaaaat ttaaaaaggc aaaaaaagat aacaaaatta ggtaaaagca ttgataaaca
      481 ggagaagaaa ctcttttttc aaaagaatat ggaagagatg aaaaaaagcg tggattacca
      541 aaatacctca aggctcagac aattctttaa gagaaggcaa tataaaaatc agattcaaaa
      601 gaagtataaa gatagtgtga aaaacagaat aaaaaaatcc tttatagagg gcagtaaaag
      661 atttggcgaa tttgtaaagg gcagagggaa aaagataata tttctatcac ttttagcggt
      721 aggaatattt tttatgttat ttcaggctgg gagcatgatg atgaatatgg gaacgggaat
      781 ggtaagtaat actgtttcaa ccacctactt atcatcagaa gacaccttaa aagaaatcaa
      841 tcagaggttt tcatctttgg aacaggcttt gcaagaagaa atggacagtg tggaggaaaa
      901 tcatccgggc tatgatgaat atattatcaa aggaaaagag aaaattggtc ataatgttca
      961 tgaactcttg tcatatatca cagcccgtta tggaattgta aagaatattt ctgaagtaga
     1021 aagtgaacta aaacatctgt ttcaaaaaat gtatacgctg acttataaag aagagattga
     1081 aatcagatat agaactgtta catccagcta tacggatgct gatggcaatg aacatactga
     1141 aagtcatgaa gagccgtatg agtataggaa actcattgta accttagaaa aaagagagat
     1201 ggacggaatt attagagaag catttaagcg ttatcctaat aatttggcac actatgaaac
     1261 tttatttttg acacaaggaa atatgggaga agtatttgga aatattgacc ttataaattc
     1321 aaatggtgga attggtggtg gtaaagagta tgaagcatca agtgaagtgc aaaagaaaat
     1381 agtgaatgcc gcttatatta caccatctcc aggagcaggt tggtgtgcca tgtgggtatc
     1441 acaggtctat caaaatgcag gacttggatt tattggagga aatgcttgtg atatgtatcg
     1501 aaattatact tttacttctg ataggtcaaa gttaaaggtt ggaatgcttg ttgcagttga
     1561 aagtagcagt agtggtagca gtttaggtgt tacctatggt catgtaggta tttatatcgg
     1621 agatggaaaa gtaatggata atatcggaca cataagagta actaccctag atgattggat
     1681 tgcaacattt tgcaaacatc accctgtagg ttttggattt cca
//
LOCUS       DARYXS010000164         1666 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.165, whole genome shotgun sequence.
ACCESSION   DARYXS010000164 DARYXS010000000
VERSION     DARYXS010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1666
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.165"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            22..420
                     /locus_tag="TV193_001925"
                     /pseudo
     CDS             22..420
                     /locus_tag="TV193_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(444..941)
                     /locus_tag="TV193_001926"
     CDS             complement(444..941)
                     /locus_tag="TV193_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HEL1514073.1"
                     /translation="MAKRQVFFSFHYDNDNWRAGQVRNMGKVDSSSTFSDNDWEEVKE
                     RTESKIKEWIDEQLNKRSCLVVLIGEKTANRKWINYEIRKAYELNKGIVGIYIHKLEN
                     SLGEQDDKGNNPFDYLTLEGEKLSKYVKCFDSNYSSSKYVYSDIKDNIEGLIEYGINH
                     KPSTW"
     gene            complement(942..>1666)
                     /locus_tag="TV193_001927"
     CDS             complement(942..>1666)
                     /locus_tag="TV193_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="USG protein"
                     /protein_id="HEL1514074.1"
                     /translation="ADEDYEYKKARQELQIEDLNRYGIFTYLVNKYDEITEILSTLVD
                     RFRRKTIFISGSAYSYSAYSQKTGENFIHKLSFELSKNGYHIVNGYGKGVGEFVLNGV
                     ADYCLTHKSKINDFLTLMPFPQNSSLGIDLDKLYKENREQMIESCGIAIFLFGNKEAE
                     DIASGVMDEYELSKKHGLVCLPIEYTGGASKEIYDQTTQEISDKNTISAIEQANKQCD
                     GDIDMSVKNIVQAVKILNKEEF"
BASE COUNT          547 a          312 c          204 g          603 t
ORIGIN      
        1 tattgttttc gaatataatc gaaatatatc ataaaagcag ccgatgaaag gcaaaattta
       61 caggataaga tcaaggctat tgataaggaa atgcaggagc tttctgccac tatggagcaa
      121 gttcacactg ttaaaaaata caggcaatac tacaaagaat ataaggcaag tccatctgac
      181 aaggcatttt ttgaagagta caaagctcag attaccttat atgaaaatgc cctttcagag
      241 cttaaaaaat catattccaa gttgccaaat tctaagggta ttttagatag acttgataaa
      301 ttgcaagaaa aaaagaatac ccttatgcaa gagtattctt cctcaaaatc tattatggac
      361 gaactttaca agatacgaaa aaattatgga atttacatgg gtaaggagat ggagagataa
      421 ttttttctct ccatcatcat ttattaccaa gttgatggtt tatggtttat tccatactca
      481 attaaacctt caatattatc tttaatatcg ctataaacat atttacttga tgaatagttg
      541 gagtcaaaac atttaacata ctttgaaagt ttttcacctt ctaatgttaa ataatcaaaa
      601 ggattattac ccttatcatc ttgctctccc agtgaattct ccaacttgtg aatataaatt
      661 cccacaatac ctttatttaa ctcatatgct tttcttattt cataatttat ccattttctg
      721 ttcgctgttt tttctccaat caaaacaacc aaacatgaac gcttatttaa ctgttcatca
      781 atccattctt taattttact ttcagttctt tcttttactt cctcccagtc attatcagaa
      841 aaggtagaac tactgtctac tttccccata ttgcgaacct gtcctgccct ccaattatca
      901 ttgtcgtaat gaaagctaaa aaatacctgt ctttttgcca tttaaaattc ctccttattt
      961 aatattttaa ctgcttgaac tatgttttta acagacatat caatatcgcc atcgcattgt
     1021 ttatttgcct gttcaattgc acttattgta tttttatctg aaatttcttg agttgtttga
     1081 tcatatattt ctttagatgc accgccagta tattcaatag gcaaacatac taatccatgc
     1141 ttttttgata actcatattc gtccataact ccgcttgcaa tatcttctgc ctccttatta
     1201 ccaaaaagaa atatagctat accacaactt tcaatcatct gctctctatt ttctttatat
     1261 agcttatcta aatcaatacc taatgaacta ttttgaggaa aaggcataag tgttaaaaaa
     1321 tcatttattt tggacttgtg agtcaaacaa taatctgcaa ctccatttaa tacaaattca
     1381 ccgactcctt taccatatcc attcacaata tgataaccat tttttgatag ttcaaaagat
     1441 agtttatgaa taaaattttc gccagttttc tgagaataag ccgaatagga gtacgcacta
     1501 ccagatataa atattgtttt ccttctaaat ctatcgacaa gagtgctcaa tatttcggtg
     1561 atttcatcat atttatttac taaatatgta aaaataccat atctatttag gtcttcaatt
     1621 tgtagctcct gtcttgcttt tttgtattca taatcctcat cagcat
//
LOCUS       DARYXS010000165         1640 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.166, whole genome shotgun sequence.
ACCESSION   DARYXS010000165 DARYXS010000000
VERSION     DARYXS010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1640
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.166"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..1612)
                     /locus_tag="TV193_001928"
     CDS             complement(<1..1612)
                     /locus_tag="TV193_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL1514075.1"
                     /translation="MGTDFFEVPRESLRNKLINGIQSFSYLELVGTSKDKNNKSPRKR
                     SDAMADSLIQISIVPQQAKNTGKTWTDNWTSDGFLRWAVSLNFVSVDRETDMFSITSK
                     GLHFSRAIINSEEETAILRKALLSYPPATQILSLLADSGTYCTKYYLGEQLGFRGEKG
                     FTSYNEDIMFDWLGSATKSEKKLIKADIEGTSDKYARGICNWLKNVGLVDSQTIKRTF
                     TNGEKDGFQGYKINGRGLHALRQAQGDSKHSKLEKFVMWEFFATHGNNREYVRTRRAY
                     IVKFLQETNSLAILLDKLRAKGFYDELEIILSDIQGLNYFGLRIDISSNRVSLKDKIN
                     DFSIPELEITQELKDEQAEKRKAKFLKETNLPMKYIELLDIAYDGKRNRDFEIVTMEL
                     FRNVYRLHSKLLGGGRKPDGLLYQDRFGVIVDTKAYGKGYSKSINQADEMIRYIEDNK
                     RRDENRNPIKWWEAFPDTIPQEEFYFMWVSSKFIGKFQEQLDYTSNETQIKGAALNVE
                     QLLLGADLVLKGQLHISDLPSYFQNKEIE"
BASE COUNT          521 a          346 c          221 g          552 t
ORIGIN      
        1 attcaatttc tttattttga aaataagatg gtaaatcgga aatatgcagt tgtcctttaa
       61 gaaccaaatc tgctcccaaa agcaattgct ctacattgag ggctgctccc ttaatttgtg
      121 tttcattaga ggtataatca agctgctctt gaaattttcc aatgaattta cttgacaccc
      181 acataaaata aaactcttct tgtggaatcg tatctggaaa agcttcccac cactttatcg
      241 gattacgatt ttcatctcgt cgcttattat cctcaatata ccgaatcatt tcatcagcct
      301 gattgataga tttagaataa ccttttccat aagcctttgt atctacaatc acaccaaaac
      361 gatcttgata gagtaaacca tctggctttc tgccaccacc taaaagctta gaatgcaatc
      421 tatatacatt tctaaataat tccattgtaa caatttcaaa atctcgattt cgcttaccat
      481 cgtaagcaat atcaagcaat tcaatatatt tcattggtaa attagtctct tttaaaaatt
      541 ttgccttacg cttttctgcc tgctcatcct ttaattcttg tgtaatttct agttcaggaa
      601 tagaaaaatc gttgatctta tccttcaaag aaactctatt gctagaaata tctatcctca
      661 aaccaaaata attcaatcct tgaatatctg ataagataat ctccagttca tcgtaaaaac
      721 ccttagccct tagtttatct aatagaatag ccaaagaatt agtttcttgg agaaacttga
      781 cgatataagc tctccgagta cgaacatact cgcgattatt gccatgagtt gcaaaaaatt
      841 cccacatcac aaatttttca agcttgctat gcttagaatc cccctgagct tgtcgtaaag
      901 catgaagacc acgaccatta attttataac cttgaaatcc atctttttca ccattagtaa
      961 aggtacgctt aatcgtttgt gaatcaacca aaccaacatt ttttagccaa ttacaaatac
     1021 cgcgtgcata tttatcactt gttccttcta tatcagcttt aataagtttt ttctctgatt
     1081 tagtggcaga tcctaaccaa tcaaacataa tatcttcatt ataggaagta aagccttttt
     1141 caccacgaaa accaagctgc tcacctaaat aatatttagt acaataagta ccgctatcag
     1201 ccaataaaga taagatttgt gtagctggcg ggtatgacaa cagtgccttt cttaaaatag
     1261 cagtttcttc ttccgaatta attattgccc tagaaaaatg caaccccttc gaagtaattg
     1321 aaaacatatc cgtttctcta tctaccgaca caaaattcag gctaacagcc catcttaaaa
     1381 aaccatctga tgtccaatta tccgtccaag ttttacctgt attttttgcc tgttgaggta
     1441 cgatgctgat ttgaatcaaa gaatctgcca ttgcatctga acgctttcgg ggagatttgt
     1501 tattcttatc ctttgatgtt ccaactaatt ctaaatatga aaatgattga atcccattaa
     1561 tcagtttgtt tctgagtgat tctcgtggta cttcaaagaa atctgtaccc aaccataagt
     1621 tcttattttc ataagagctc
//
LOCUS       DARYXS010000166         1634 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.167, whole genome shotgun sequence.
ACCESSION   DARYXS010000166 DARYXS010000000
VERSION     DARYXS010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1634
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.167"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            6..263
                     /locus_tag="TV193_001929"
     CDS             6..263
                     /locus_tag="TV193_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HEL1514076.1"
                     /translation="MDNVKEASTVSTASGENYEYVVLQVTLKEKLIGTGSGNLTELEN
                     VINKQAKKGYRLHTITTSNGGSKGFGGGDRIQATMVFEKIK"
     gene            391..1530
                     /locus_tag="TV193_001930"
     CDS             391..1530
                     /locus_tag="TV193_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1514077.1"
                     /translation="MWSEKHKSGKVNFVERYKHPYTGKWCRASVLMEKDTPRIRKEAQ
                     KYLDEKISKILTSLTTTDAYLLDVMNEWWEHHQKSLKSTSVRSLDFRIRELRNLIDPE
                     VMIAKITTKYLQSIIDKIPGSYDKRKRARQLLKQTFDYAIALEYVSINPVISTQLAKP
                     VKTIKDFEDVAQKFLEKDELKRLLDEMYRRKGSIKMAYLAEFMSLNGCRIGEALAIQP
                     DNIKNDIIEIHGTLDYTSNGYRNAIKTTPKTNSSWRETLITKREKEIIQDILKINALE
                     KNTNPNYKDMGYIFISRNGVPIQDNALNTSIRAANKRLEKPIQKELTSHIFRHTLVSR
                     LAENKVPLKTIMDRVGHADSKTTQQIYTHVTKSMKNEVVDILNRL"
BASE COUNT          624 a          323 c          287 g          400 t
ORIGIN      
        1 gatttttgga caatgtaaaa gaagctagta ctgtttcgac tgcttctggc gaaaattatg
       61 aatatgttgt gctacaagtt acactaaaag aaaagcttat aggaacaggc tcaggaaatt
      121 taactgaact tgaaaatgtt attaataagc aagcaaaaaa aggatatcgc ctacacacta
      181 ttaccacatc aaatggtggc agtaaaggat ttggtggcgg agatagaata caagctacaa
      241 tggtatttga gaaaatcaag taaaataaaa aaagccctac gctcaaattt tggtcggtgc
      301 gagcgtgagg caaatctagt atagtaaaaa cctgcttcgc agtaggtctc tttactatac
      361 ctattttaac agaaaatgag gtaaaaaaca atgtggtcag aaaaacacaa aagcggaaaa
      421 gtaaattttg tagaacggta caaacacccg tatactggca agtggtgcag agcttctgtc
      481 cttatggaaa aagacacgcc acgaatacga aaagaagccc aaaaatatct tgacgaaaaa
      541 atatctaaaa tcttaacaag tcttaccaca accgatgcct acctactaga tgtcatgaac
      601 gaatggtggg aacatcatca gaaatcactc aaatcaactt ctgtccgctc tcttgatttt
      661 agaataagag aattgcgaaa cttaattgat ccagaagtga tgattgccaa gataaccacg
      721 aaatacctgc aaagtattat cgacaaaata ccaggtagtt atgacaaacg taaacgagca
      781 cggcagctgc tcaaacaaac cttcgactac gctatcgctt tagagtatgt ctcaatcaat
      841 ccagttatta gtacccaact cgcaaaacct gttaagacca tcaaagactt tgaagacgtt
      901 gcccagaagt ttttagaaaa agatgaactc aaaaggctat tagatgaaat gtatagacgt
      961 aaaggatcga ttaaaatggc ttatctggca gaatttatga gcttaaatgg ctgccgcatt
     1021 ggagaagctc tagctataca gccagacaat atcaaaaatg atatcattga aatccacgga
     1081 actcttgact acacctcaaa tggctataga aacgctatca aaaccacccc taaaacaaat
     1141 tccagttggc gtgaaacatt gataaccaaa cgtgaaaaag aaattattca ggatatactg
     1201 aaaattaatg ctcttgaaaa aaatactaat cctaattaca aggacatggg ctacatcttc
     1261 atttccagaa atggtgttcc tattcaagac aacgccctca acacctctat cagagcggca
     1321 aataagagac tagaaaaacc gattcaaaaa gaactcacca gccacatctt ccgtcatacc
     1381 ctggtgagtc gccttgcaga aaacaaagtg cccttaaaaa ctatcatgga tagagttgga
     1441 catgctgact cgaaaactac tcaacaaatc tatacccacg tcacgaaaag catgaaaaat
     1501 gaagtcgtcg acatcttaaa tcggctataa tatgccccaa aaatgcccca aaacacaaga
     1561 aaaaaccttg acatcttcaa caaacgttga tatgacaagg ttttttaatg ttttatttaa
     1621 tcacttattg attt
//
LOCUS       DARYXS010000167         1633 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.168, whole genome shotgun sequence.
ACCESSION   DARYXS010000167 DARYXS010000000
VERSION     DARYXS010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1633
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.168"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..748
                     /locus_tag="TV193_001931"
     CDS             <1..748
                     /locus_tag="TV193_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1514078.1"
                     /translation="TNKEVTMTTANEIVQYCVDLANSGMGVDKDGCFGTQCADLPCFI
                     VKNWFGIDLWGNAIDLLNSASAQGLEIIYNAPGVNPRAGDLFVMEVAGSPYGHTGAVI
                     EDSDGYTIKTVEQNIDGNWDSLQVGGPARFNTRDFTGVVGWIRLPVDHTKQTVDTAPQ
                     TSDTIVETPKTGTFTVDVAEINIRRWPSLASEVVGSYKQDDTVSFDSEGYANGYYWIS
                     YVGDSGKRNYLAIGQTDKDGNRISLWGKLN"
     gene            883..1425
                     /locus_tag="TV193_001932"
     CDS             883..1425
                     /locus_tag="TV193_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1514079.1"
                     /translation="MTEALFVANYIIEYCNDHNLEINNLRIQKLLYFINARNLVENGS
                     PLFQDKIEKWKFGPVVPKVYHEYKRFGASTITKDDISAQIWKFNFEVSPFGEESPIEV
                     LTYNKEEFSDSQIQLIESTILALKKYSTFKLVDLTHEDDMWKSDNQLIMSGEKGLTYD
                     NNEIRDFFMSHIESQIWNNI"
     gene            1429..>1633
                     /locus_tag="TV193_001933"
     CDS             1429..>1633
                     /locus_tag="TV193_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514080.1"
                     /translation="MNNLYATINKLNKVEQSVFLVINDIIDNNTVFPDVNARNSLKKI
                     AISTLGDRTFSTPYDFISEHIYNN"
BASE COUNT          554 a          258 c          341 g          480 t
ORIGIN      
        1 aactaataag gaggtaacga tgacaaccgc aaatgagatt gtacaatact gtgtcgacct
       61 agccaattca ggcatgggtg ttgataaaga tggctgtttt gggacgcagt gtgcggactt
      121 gccatgtttt atcgtcaaaa actggttcgg cattgattta tggggtaatg cgattgacct
      181 gttaaatagt gcatctgcgc aagggctaga gatcatatat aatgctcccg gagtcaatcc
      241 tagagctggt gacttatttg tcatggaggt agctggtagt ccctacggac acacgggagc
      301 tgttattgag gacagtgatg gctatactat taaaaccgtt gagcaaaata ttgacggtaa
      361 ctgggatagt cttcaggtag gtggtcccgc tcgctttaat actcgtgact ttactggtgt
      421 tgtcggctgg attagattac cggttgatca cactaagcag acagtagata cagcaccgca
      481 aacgtctgac actatcgtag agacaccaaa aacaggtact tttaccgtag atgtcgcaga
      541 aatcaatatc agacgttggc caagcctagc gagtgaagta gtaggtagct acaaacaaga
      601 tgatactgtc agttttgata gcgagggcta cgctaatggc tactactgga ttagctatgt
      661 tggcgactca ggcaagcgta actacctagc tattggacag acagataaag atggcaatcg
      721 catcagcctt tggggtaaat taaattagat aagacaaacg ccctcgcttt tgcgggggct
      781 gtttttatta tcaaaatcaa tatgtagtgt tagctaaaaa gttagctaac aagatatagt
      841 acttgacaaa tatgttataa ttaaaaaaag gaggtggact ggatgactga ggcactgttt
      901 gtagcaaatt acatcattga atattgcaat gatcacaatt tagaaataaa taatttaaga
      961 attcagaaac ttttatactt tataaatgct cggaacttag ttgaaaatgg cagcccactg
     1021 tttcaggata agatagaaaa atggaaattt ggaccggttg ttccaaaagt ctatcatgaa
     1081 tataaaagat ttggagcgtc tacaattacc aaggatgata tttctgctca gatttggaaa
     1141 ttcaactttg aggtaagccc ctttggagaa gaaagcccaa ttgaagtatt gacatataat
     1201 aaagaagaat tttcggattc tcaaattcaa ttaattgaaa gtacaatact cgcattaaaa
     1261 aaatatagca catttaaatt agtagatttg acacatgaag atgatatgtg gaaatctgat
     1321 aatcaactca taatgtctgg tgaaaaaggt ttaacttatg acaacaatga aataagagat
     1381 tttttcatgt cgcacattga gtctcaaata tggaataata tttagcaaat gaataatctt
     1441 tatgcaacta ttaataagtt aaacaaagta gaacaatctg tttttttagt aattaatgac
     1501 attattgata ataatactgt tttccctgat gtaaatgctc gcaatagttt aaaaaaaata
     1561 gctatttcaa cacttggcga tcgaactttt agtacaccat acgatttcat ttctgagcat
     1621 atatataata atg
//
LOCUS       DARYXS010000168         1617 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.169, whole genome shotgun sequence.
ACCESSION   DARYXS010000168 DARYXS010000000
VERSION     DARYXS010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1617
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.169"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..317)
                     /locus_tag="TV193_001934"
     CDS             complement(<1..317)
                     /locus_tag="TV193_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1514081.1"
                     /translation="MTFLDDIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVVG"
     gene            complement(433..804)
                     /locus_tag="TV193_001935"
     CDS             complement(433..804)
                     /locus_tag="TV193_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEL1514082.1"
                     /translation="MFIFLRQLIQTQDGKILFTLGAIAVAMMIDFLTGTVAAKINPNI
                     DFRSKEGINGILRKICSIALMIFFIPLSILLPNDTGVAFLYVMYVGYLLFELKSILEN
                     LNKMGIDVALFKQFIDMFSKK"
     gene            complement(815..1426)
                     /locus_tag="TV193_001936"
     CDS             complement(815..1426)
                     /locus_tag="TV193_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1514083.1"
                     /translation="MRNWKVTGKYPQYDGTGAVASTHIIIAAEDGAVIPQLIKQDLTS
                     TSDTEIIKAALEEFKKAEYVEIAMGEAVQKVDDLEKLSQATAKTATTAQAAAGLAKLS
                     AERTQKMINLQTIHMLTSVDKIEPDIYKGMLELIEPGKKGQYQEHDVFTVVDESHEDL
                     AGEGKLVFVYVNEAFTYDKQTLKDLESEDKVTVIKYADLVKGK"
     gene            complement(1430..>1617)
                     /locus_tag="TV193_001937"
     CDS             complement(1430..>1617)
                     /locus_tag="TV193_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1514084.1"
                     /translation="ELNDFLDELANEPIVIKGHEYSKRFIDFLEYLAEAEDEFTGAEI
                     ILIDNILEQYEANKKGE"
BASE COUNT          433 a          372 c          308 g          504 t
ORIGIN      
        1 ccgacaactg atttgtagcg tggattgtct actaaaaact ggccatgatc aaggatcgac
       61 tcgtcccagc tatcataggc cctaaaacga tctacaatat ccgttacaac acccggctga
      121 tactcctcct gagtttttgt attaaatgac ttacccgtcc aagagctatc tgccttgata
      181 ccaaatagag cgttatgtgg ggcgtacttg ccccaaccac tctcaaggat tgcctgtgct
      241 gcggtcaacg atggcaagat tttatacttt gtccagccat ctaagcagcc ttgcttaatg
      301 tcatctaaaa aggtcatctg tcctccttat ctaaaaacgg ataaacaatc agagcaatca
      361 cagatagcgg taaatatagt attgtgattg ctatgactat tgctaatcgt gtgattgctc
      421 gcatatctcc ccctattttt tactaaacat atcaataaat tgcttaaaca aggctacatc
      481 aatccccatt ttgtttagat tttctaggat tgattttagc tcaaagagca gatagccaac
      541 gtacatgaca tacaaaaagg ctactcctgt atcgtttggc aacaagattg acaaagggat
      601 aaaaaagatc atcagggcaa ttgagcaaat tttgcgcaaa ataccattaa tcccctcttt
      661 gctcctaaaa tcgatgttgg ggttgatttt tgctgcaacg gtacccgtta aaaaatcaat
      721 catcattgcg actgcaattg ctcctaaagt aaataggatt ttaccatctt gggtctggat
      781 taattgtctc aaaaaaataa acatggatca cctcttactt gcctttaacc aaatcagcgt
      841 acttgataac tgtgacttta tcctctgatt ccagatcttt gagggtttgc ttgtcatagg
      901 taaaggcctc gttaacatac acaaagacaa gtttaccctc gccggccaag tcctcgtgag
      961 actcatctac aacagtaaag acatcatgct cttgatattg cccctttttg cctggctcga
     1021 taagctctag catgcctttg taaatgtcag gctcgatctt atcgacgctg gtcaacatgt
     1081 ggatagtttg taagttaatc atcttttgcg tgcgctctgc ggacaattta gctagccctg
     1141 ctgcagcctg tgcggttgtt gctgtcttag cggtcgcttg tgagagtttt tcgagatcat
     1201 caactttttg cactgcttcg cccatggcaa tttcaacgta ttctgctttt ttaaattcct
     1261 ccaaggcagc cttgataatc tctgtgtcgc tagtggacgt caggtcctgc ttaatgagtt
     1321 gagggataac agctccgtcc tccgcagcga taatgatatg tgtgcttgcg actgctcctg
     1381 taccatcata ttgtgggtat ttacctgtga ctttccaatt acgcataatt tactctcctt
     1441 ttttatttgc ttcgtactgc tctaaaatgt tgtcgattaa gatgatttcg gcccctgtaa
     1501 actcatcttc ggcctcggcc aaatactcca aaaaatcaat aaatcgctta gagtactcat
     1561 ggcctttgat gacgataggc tcgttggcta actcgtctaa aaagtcgtta agctcag
//
LOCUS       DARYXS010000169         1598 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.170, whole genome shotgun sequence.
ACCESSION   DARYXS010000169 DARYXS010000000
VERSION     DARYXS010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1598
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.170"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            81..638
                     /gene="efp"
                     /locus_tag="TV193_001938"
     CDS             81..638
                     /gene="efp"
                     /locus_tag="TV193_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEL1514085.1"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDETAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
     gene            681..1070
                     /locus_tag="TV193_001939"
     CDS             681..1070
                     /locus_tag="TV193_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1514086.1"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            1063..1515
                     /gene="nusB"
                     /locus_tag="TV193_001940"
     CDS             1063..1515
                     /gene="nusB"
                     /locus_tag="TV193_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEL1514087.1"
                     /translation="MTKHFQHSRRDLRERAFQALFAMEMGGDFLPASQFAYDYDKEAA
                     DDKQPSELPVFLLNLVNGVMDHKAELDEVIKKNLKTSWSIERLTVVDKTMLRLGLFEM
                     TLFEETPDRVALNEIIEIAKKYSDDTSAKFINGLLSQFVSDESAAVTE"
BASE COUNT          480 a          288 c          371 g          459 t
ORIGIN      
        1 aatggtcata aaacatttga gcctacagct cttttgtggt aaaataagac gataactatt
       61 ttagtaagag gtaataacaa atgattgaag caagcaagct tagagcaggt atgacgtttg
      121 aagcagaagg aaagctaatt cgcgtacttg aagcaagcca tcataagcca ggtaagggaa
      181 acactatcat gcgtatgaaa ttgcgtgatg ttcgtactgg ctctacattc gacacaacct
      241 atcgtccaga cgaaaagttt gaacaggcta ttatcgaaac agtgccggct caataccttt
      301 acaagatgga cgagactgct tactttatga atactgaaac ctatgaccag tatgagattc
      361 cagtagccaa tgttgagcaa gagctattat atatccttga aaactctgat gtgaaaatcc
      421 agttttatgg aacagaggtg atcggagttc aggtaccgac tactgttgag ttgactgtta
      481 cagagaccca gccatcaatc aagggagcaa ctgttacagg ctctggtaag cctgcaaccc
      541 ttgaaacagg actcgtggta aacgttccag actttattga ggtaggacaa aagctaatca
      601 tcaatactgc tgaggggact tacgtttctc gcgcttaatt cgctttccgg aattagtcta
      661 agagaaagaa aggaaatgct atgacaactg aaaatatcgg tgaaattgtt atttcgccac
      721 gagttcttga ggttattacg ggaattgcta cgatgcaggt cgagggtgtt cactcgcttc
      781 acaataaaaa catggcagat acctttaata aagctagtct tggtaagggc gtctatcttc
      841 agacggaaga aaatggaaca gtcaatgcag acatctatgt ttacctgcaa tatggtgtaa
      901 aggttcctgc ggtgtcaatg gctattcaaa gggctgttaa gtcagctgtt tatgacatgg
      961 ctgaggttac catttcttat gttaatatcc atgttgaggg gattgttcct gaaaagacac
     1021 caaagccaga aatgaaatca ttgtttgatg aggatttttt ggatgactaa gcattttcaa
     1081 cattcgagaa gagatttgcg tgagcgtgct tttcaagctt tatttgctat ggagatgggc
     1141 ggagattttc tgcctgcctc acagtttgcc tatgactatg acaaggaagc agctgatgac
     1201 aagcagcctt ctgagcttcc tgtttttctg ttaaatcttg tcaatggcgt tatggatcat
     1261 aaggctgagc ttgatgaggt tatcaagaaa aaccttaaaa cgagctggtc cattgagcgc
     1321 ttgacagtgg tagacaagac gatgttgcgt cttgggctct ttgagatgac cctgtttgag
     1381 gagacacctg atcgtgtagc cttaaatgaa atcattgaaa ttgctaaaaa atattctgat
     1441 gatacctcag ctaagtttat taatggctta ctcagtcagt ttgtttctga tgagtcagct
     1501 gcagtgacag aataacaagc tggtgaaagc ttcttaagtt actaaagccc tatagggctt
     1561 tttgaatgct caaaaacgtc tcatctggtt ggctatgt
//
LOCUS       DARYXS010000170         1588 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.171, whole genome shotgun sequence.
ACCESSION   DARYXS010000170 DARYXS010000000
VERSION     DARYXS010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1588
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.171"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..413)
                     /locus_tag="TV193_001941"
     CDS             complement(<1..413)
                     /locus_tag="TV193_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEL1514088.1"
                     /translation="MLSKQKLSLEISHYLISGLLTTILYFVFRYVIYSWLHQATISAG
                     FANIIAIIAAFLMNDSYVFKQTSEKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV
                     IGSLVEHDSESINSVESILSQAIMISLNFIVSKYY"
     gene            614..1306
                     /locus_tag="TV193_001942"
     CDS             614..1306
                     /locus_tag="TV193_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1514089.1"
                     /translation="MFSGIQLKTARLSRHISQEQLGQLLGVNKMTISNWEKEKNRPNQ
                     KHFEELVSIFQLPAEYFYQENRLLLPYSQLSASNKEKVISYSESLLEQKEKIIALPAK
                     KKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEV
                     VLIKQDSFDYDGAIYAVEWEEQTYIKKVYREENGLRLVSLNKKYPDKFASFDDNPRII
                     GKIIANFMPLDV"
BASE COUNT          523 a          253 c          279 g          533 t
ORIGIN      
        1 atatagtatt tactaacaat aaaattcaag ctaatcatta tggcttggct caaaatgctt
       61 tcaacagaat taatgctttc agaatcatgt tcaacaaggc ttccaatgac ctctgggtat
      121 ttttcgacta ataaataggc taatagcata tctaagccta atgttactac tctagctagg
      181 aaaaacatgg caaatctaaa caagcgtttt tcagaagttt gcttaaaaac atagctatcg
      241 ttcatcaaga aggcagctat gatcgctata atattggcaa agcctgctga tatggtggcc
      301 tgatgtaacc atgaatagat gacataccga aaaacaaaat aaagaatggt tgttagaaga
      361 ccagatatca ggtaatgact gatttcaagt gataattttt gtttgctaag catttttctt
      421 tcctatgtgt atttatcttg actgttatat tttgatggat ctatataagt ataacatgtt
      481 tggcattaaa cctaagacag cttactgtct tttcgatata aacataaaaa gcttgaatat
      541 tcttataagc tatgttatac tctggtaaag ttaatacttt actagagtat actgacaaag
      601 gagatttatg ctgatgtttt ctggtattca attaaaaaca gcacgtttat caaggcatat
      661 tagccaagaa cagctaggac agcttttagg agttaataaa atgactattt ccaattggga
      721 aaaggagaaa aatagaccaa atcaaaagca ttttgaagag cttgtgagca tttttcaatt
      781 acctgctgag tacttttatc aagaaaatcg tcttttactt ccctatagtc agttaagcgc
      841 ctctaataaa gaaaaagtta tcagctattc tgagagctta cttgaacaaa aagaaaaaat
      901 aattgcttta ccagctaaga aaaagacact ttacccttat cgtgtttatg aaaggttgtc
      961 tgcagggact ggctattctt actttggtga tggtaatttt gatgttgtct tttacgatga
     1021 gcagttagat tatgattttg cttcatgggt ttttggtgac tccatggagc caacctattt
     1081 gaatggcgag gttgttctca tcaaacagga tagctttgat tatgacggtg ctatctatgc
     1141 tgttgagtgg gaagaacaaa cctatatcaa aaaagtatat cgtgaagaaa atggtctgcg
     1201 tttggtttca ttgaacaaaa aataccctga taaattcgct tcctttgatg acaatccgcg
     1261 tattattgga aaaatcattg ccaactttat gcccttagat gtataagcct ttgtattagc
     1321 ttaaaagcat gactgttgta caaccaaact cattgcatga cattggtgca ttatttttga
     1381 agtggcttct acttctttga tttacttttc tgcattaaaa agcccattaa aggtttttga
     1441 aacttattac ttagacaaag gctctattaa aaatcataac caaccggtgg tggtttattt
     1501 gtcatgtacc ttgcattttg tgacagactt cataaaacga acaaaacaca tcgctaaaag
     1561 attttaccat cttaaagtta tgtgtttt
//
LOCUS       DARYXS010000171         1513 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.172, whole genome shotgun sequence.
ACCESSION   DARYXS010000171 DARYXS010000000
VERSION     DARYXS010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1513
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.172"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..>1513
                     /locus_tag="TV193_001943"
     CDS             <1..>1513
                     /locus_tag="TV193_001943"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HEL1514090.1"
                     /translation="EKIDNIRQIIEDWNNNQLLTEYEYFYLLNALIEAIPYVSNITGT
                     YGAFLKHWDNRALHSLTLAEETIFDNYRPNKAFNENANELVKKIKADIVYIDTPYNAR
                     QYASNYHLLENIARHQKPILKGITKIFDWKTLKSDYSTKTKALKAMEDLIANINASHI
                     ILSYNTEGIISEEDLTLLLQRYSFNNQIDVKRIPYRKYQSKKKSQNKDLYELLFYIQR
                     KPINNRFKSQTKKKAAIISQKKYIKSPLNYIGGKYRLLNQIIPIFPRHINTFVDMFSG
                     GANVGINVPAKKHIFNDMNYRINDMFRYFQSHDPLEILEQIEHRISEYQLSKTNEQGF
                     LTFRKHYNTHPNPLDLYVLSSYSYNYQFRFNNSMEFNNPFGRNRSHFSENMKSNLLNF
                     VARLHRLDATFSDQFFSDFDISTLSIDDFVYLDPPYLITTGSYNDGNRGFTNWGEKQE
                     IEMYQLIRDLNKKQIKVALSNVLVHKGKHNDLLEQFVQDESLYLTTLNYNYKNA"
BASE COUNT          572 a          269 c          208 g          464 t
ORIGIN      
        1 tgaaaaaatt gataatatca gacagatcat agaagattgg aacaacaatc aattactcac
       61 agagtacgaa tatttttacc ttttaaatgc tttgatagaa gctattcctt atgttagtaa
      121 tattactgga acctatggcg cttttctcaa gcattgggac aaccgagcgt tgcattcctt
      181 aacattagca gaagaaacta tttttgataa ttatcgtcct aacaaagcgt ttaatgaaaa
      241 tgctaatgaa ttagtcaaaa aaataaaagc agatattgtt tacattgata ccccctacaa
      301 tgctcgacaa tacgcatcaa attatcattt actcgaaaac atcgcccgac atcaaaagcc
      361 aattttaaaa gggattacta aaatttttga ttggaaaact cttaaaagtg attattcaac
      421 aaaaacaaag gctttaaaag caatggaaga tttaattgct aatattaatg ctagtcatat
      481 cattctaagt tacaataccg agggtattat atccgaagaa gatttaacac ttttacttca
      541 acgatattcg ttcaataatc aaattgatgt gaaacggatt ccttaccgaa aatatcaatc
      601 taagaaaaaa tctcagaaca aagacttata cgaacttctt ttttatattc aaagaaagcc
      661 gataaataat cgcttcaaat cacaaactaa aaaaaaggca gccatcatca gtcaaaaaaa
      721 gtatataaaa agcccattaa attatatcgg tggaaaatat cgactgctaa atcaaatcat
      781 tccaattttt ccccgacata tcaatacatt tgttgatatg tttagtgggg gggcaaacgt
      841 tggtatcaat gttcctgcta aaaaacacat ctttaatgat atgaactatc gcattaatga
      901 catgtttcga tattttcaat cacatgaccc acttgagata cttgaacaaa ttgagcatcg
      961 aatttcagaa tatcaactca gcaagaccaa tgaacaaggc tttttaacat tccgaaaaca
     1021 ttataatact catccaaatc cactagactt atacgtacta tcgtcttata gctataacta
     1081 tcaatttcgc tttaataact caatggaatt caataaccca ttcggcagaa atagaagtca
     1141 ttttagtgaa aatatgaaat ccaatctact caattttgta gctcgactac accgtttaga
     1201 tgccactttc tctgatcaat ttttctcaga ttttgatatt tctacattat caatagatga
     1261 ttttgtttat cttgatcccc cctacctcat aacgactggc agctataatg atggaaatcg
     1321 tggcttcaca aactggggcg aaaaacaaga aattgaaatg tatcaattaa taagagacct
     1381 taacaagaaa caaattaagg ttgcacttag taatgttctt gttcataaag gaaagcacaa
     1441 tgatttactt gagcaatttg ttcaagatga aagtctatat ctcaccactt taaattacaa
     1501 ttataaaaat gct
//
LOCUS       DARYXS010000172         1503 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.173, whole genome shotgun sequence.
ACCESSION   DARYXS010000172 DARYXS010000000
VERSION     DARYXS010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.173"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            71..1468
                     /locus_tag="TV193_001944"
     CDS             71..1468
                     /locus_tag="TV193_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEL1514091.1"
                     /translation="MIESKKYLVIKAVCEGKKQKNRACVELGLSKRQVNRLILAYREK
                     GKSAFVHGNRSKRPTHAMSLETKRRIIEKYQSYGDLRPNVVHFCELLAEEENIAYSDT
                     TVRKLLYQAGFLSPKTQRATKRRLKQEAKQKKREAEKRGSKLPTASNFFEEPDKAHPS
                     RARKKFKGELIQMEASQFPWFGQQETHLHVAIDDASGDIVGAYFDTQETLNGYYHVLE
                     QILEVHGIPFQFLTDKRTVFTYASSQSKKIEEDTFTQFGYACHQLGIAIETSSIPQAK
                     GRVERLNQTLQSRLPIDLQRNQITSISQANRYLKRWIKRFNKQFGGLASESVFEKAPK
                     PAQRNLLLARISERVIDSGHHIRYQNNFYLPVEGDKKIYFTRKTKALVIEAFDGDIYL
                     NIADNIYATRKLPKHEKHSKEFEMVPKTKKERRKYIPPQSHPWKLASFKQYLHKIGKS
                     YEEFKRERNTSQPQL"
BASE COUNT          530 a          300 c          299 g          374 t
ORIGIN      
        1 gtcttagcta ggtcgaatgt gaaaatgtcc cgtctgttaa actagaaaga tgaggaaaat
       61 agaactaact atgatagagt caaagaaata cctagtcatc aaagctgttt gtgagggtaa
      121 aaaacagaaa aacagggctt gtgtagaatt agggttaagc aagaggcagg tgaaccgatt
      181 gatactagcc tatcgagaga aaggaaagtc agctttcgtt catggtaata gatcaaaaag
      241 accaactcat gccatgtctt tagaaacaaa gagaaggatt atcgagaaat atcaaagtta
      301 cggtgattta agaccaaatg ttgttcattt ctgcgaacta ctagcggaag aagaaaacat
      361 cgcctattca gatacaactg ttagaaaact actctaccaa gcagggtttc tatctccaaa
      421 gactcaacga gcaacgaaaa gacgattgaa acaagaagcc aaacaaaaga aaagggaggc
      481 agaaaaaaga ggatccaaac tcccaactgc ttccaacttc tttgaagaac ctgacaaagc
      541 tcatcccagc cgagcaagaa agaaattcaa aggggaactc attcaaatgg aggccagtca
      601 attcccttgg tttggacaac aggaaacaca tcttcatgtc gctattgacg atgcctccgg
      661 tgatattgtc ggggcttact ttgatactca ggagacgcta aacgggtatt atcatgtctt
      721 agaacagatt ctagaggtac atggtatccc tttccagttc cttactgata aaaggactgt
      781 attcacttat gcttccagtc agtctaaaaa gatcgaggaa gataccttta cacagtttgg
      841 atatgcttgc catcagcttg gtattgccat tgaaacgtct tctatccctc aagctaaagg
      901 gcgtgtagaa cgtcttaatc agacccttca atcgcgtcta ccaattgatt tacagaggaa
      961 tcaaattacc agcatctctc aagcgaatcg ttatcttaag agatggatta aacgatttaa
     1021 caagcagttt ggtggactgg ccagtgagtc tgtttttgag aaagcaccta aaccggccca
     1081 gcgaaaccta ctgttagcga gaatctctga aagagtaatt gatagtgggc atcatattcg
     1141 atatcaaaac aacttctact tgcccgtcga aggggataaa aaaatctatt ttacgcgtaa
     1201 gacaaaggca cttgtgattg aggcattcga tggagacatc taccttaata tcgcagacaa
     1261 tatttatgcc actagaaagt taccaaaaca cgagaagcac tccaaagaat tcgaaatggt
     1321 gcctaaaact aaaaaagaaa gacgcaagta tattccacca caatcccatc cgtggaaact
     1381 tgcatctttc aaacaatacc ttcataaaat cggaaaatct tatgaagaat tcaagcgtga
     1441 gaggaatacc tctcaaccac aattataaca gatttttctc ttatctaacc gattttttca
     1501 aga
//
LOCUS       DARYXS010000173         1422 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.174, whole genome shotgun sequence.
ACCESSION   DARYXS010000173 DARYXS010000000
VERSION     DARYXS010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1422
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.174"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..230
                     /locus_tag="TV193_001945"
     CDS             <1..230
                     /locus_tag="TV193_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514092.1"
                     /translation="LGLFPFGKAIEIGQGAGSLLLNIIWIVCCGWSLAIMHLTSALLL
                     CLTIVGIPFARQSLKLAKISLFPFGAIIYDI"
     gene            249..893
                     /locus_tag="TV193_001946"
     CDS             249..893
                     /locus_tag="TV193_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1514093.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGANGDSPLLESSKDDLRQLARELW
                     DISFDAIYSSDLKRAVDTARIIVDEANCKTDISYTKQLREWNLGTLEGTKIATVSAIY
                     PSQMSAFYHNLAKFKPSQFKAESLYESTQRLYQLIKSLEDKAYQQVLMVGHGAHLTAS
                     IRALLGFEPGMLRAQGGLDNASLTVIETLDFKHFHCLRWNDTSFLQKKTTRLTP"
     gene            complement(1324..1422)
                     /locus_tag="TV193_001947"
                     /pseudo
     CDS             complement(1324..1422)
                     /locus_tag="TV193_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          420 a          300 c          273 g          429 t
ORIGIN      
        1 ctttgggtct ttttcctttt ggaaaagcca tcgaaattgg ccaaggagca ggcagcctgc
       61 tgctcaatat catctggatt gtctgctgtg gctggagctt agcgatcatg catttgactt
      121 ctgcccttct cttgtgcctc acgattgttg gcattccatt tgcccggcaa tctctaaaat
      181 tggccaagat tagcctcttt ccttttggag ccatcattta tgacatttaa ttaggaagca
      241 aaagacttat gaaattgtat tttgtcagac atggtaaaac cttgtggaac ctagagggcc
      301 gttttcaggg agctaacgga gattcgccct tgcttgaaag ctctaaggac gatttgcgcc
      361 agctagcaag agagctgtgg gacatttctt ttgatgcgat ctactccagc gacctaaaaa
      421 gagctgttga tactgctcgc attattgtgg acgaagctaa ctgcaagact gatattagtt
      481 ataccaagca gctgagagaa tggaacctag gcaccctgga aggaaccaaa atagcaactg
      541 tatccgccat ctaccccagt cagatgtcag ccttttatca caatttagcc aaattcaagc
      601 ccagtcaatt taaggctgaa tccctttatg aaagcacaca aaggctttat cagctcatta
      661 aaagtttgga agataaggcc tatcagcagg ttttaatggt aggacatggc gcccatttga
      721 cagcttctat tcgtgctctt ttaggctttg agccaggtat gcttcgggca cagggaggac
      781 tggataatgc cagcctaacc gttatagaaa ccttggattt caaacacttt cattgtctaa
      841 ggtggaatga tacatcattt ttacaaaaaa agactactag attaacaccc tagtagctct
      901 taagcacaaa gctccaagac agctaaactg tactccattg gttagagaac acatctcatt
      961 ttttgaggga cgctttatta gctgtaggaa gttatgaaaa gctaaataca cgagaggact
     1021 aaattggaca agctcaaaag tttgacaatg tatttcaaaa aaggattgaa ttctgtatcg
     1081 aacaggactc agtccttttt atcatttatc aagccgacca aggctttcaa ccacgacaaa
     1141 cgcgcaaaac agttatttcc tgatgatagt agagactaca gcagatattt tcaatgattt
     1201 tcttgtagta acatctatac aaaacaatac agctcattga aatataggaa cattaaaatt
     1261 cagaaagatt tcttttcttg ctaaaaatct ttcatccatt tcaaactggt tttcatttgt
     1321 cctctccttt ttcagttctg ctttttctcc ataagctgca cagttgatgt actccttgcc
     1381 tttaccgtac ttctttacaa atgtaaaatt tacaacttat ac
//
LOCUS       DARYXS010000174         1418 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.175, whole genome shotgun sequence.
ACCESSION   DARYXS010000174 DARYXS010000000
VERSION     DARYXS010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1418
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.175"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            432..1181
                     /locus_tag="TV193_001948"
                     /pseudo
     CDS             432..1181
                     /locus_tag="TV193_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241300.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
     gene            1275..>1418
                     /locus_tag="TV193_001949"
     CDS             1275..>1418
                     /locus_tag="TV193_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1514094.1"
                     /translation="MEKQNSLTQFQELNSSELNQITGGDWWSEILNFNRSQKYKHTSV
                     GSNN"
BASE COUNT          553 a          271 c          201 g          393 t
ORIGIN      
        1 catcaataca gtcaactagc aacaatgcta tcgttaaaaa taatcttaaa gaaaaccaac
       61 tcgttaaaaa aggaaaacgt ttaatcaaat ataaagaaac cattgagagt tctcaaaaga
      121 attctctaga atcacaatta aatacgttga ataaacaaaa agttggttta gagacattga
      181 aagaaagtct caaacaagga acgaacctct taccacaaaa tgatgaattt ggtcttgctg
      241 acaccttcaa caactttata aatcagtctc aagagattaa acttggtatc gctaaaataa
      301 atacagaagt atccaatcaa tccacacttg caaataacac ccttgctgca attgatactc
      361 aaatcaatac tataaaccag cagatttcag aatatgaaga tcttcgtcaa gctatctcaa
      421 atcataacac aatcttacca actggtaatc ctcatcaaga tattctcaat aattatctgt
      481 ctcaatcaca agaagaataa acttccacgt ctaaccagtt tatctctcag attaaccaga
      541 ctatttcagg tttagaatca tccctctctg ggcttagcat tcaaagagca ggtactggta
      601 gtagtgcaac atacgataac agttcagaaa ccaaagttga agtcttgagg actcaatttc
      661 tacagaatgc ttcacaacag ctgtcaacca tcgacagtca aatcactgaa cttaaagctc
      721 agctagaaca agcaagtgta tagttagaca ctaatgttgt tttagcacca gaaaccagga
      781 ttattcatct aaataatgaa tacgagggga aaagtcttat cccaaatggt agtgatattg
      841 ccaaaatcta tcctaatatt actcaaacta gaaaagctct gattacatac tttgtaactt
      901 ctgattatgt ttctctcctt aaaaaaggtc aaactgttcg tctaaatctt caaaaagtga
      961 gaaaacagtc catcactgtt aatggaaaaa tttctactat tgataaaaca gcaacaaaaa
     1021 cagaacaagg taatcttttc aagattacaa ctcttgccaa actcccttcc aaggatagct
     1081 acttgataaa atatggtgca cagggtcgtg ttacaagtgt tatcgctaaa aaatcctact
     1141 tcgactttta taagaataaa ctgttgtcaa atcatgatta aaccattccg gacgtttcga
     1201 tgaccattta ggatttagag aaataatata ttgatcttaa attataatat tagaaaaaag
     1261 aaggaggtcc acaaatggaa aaacaaaatt cactcactca atttcaagaa ctaaattcat
     1321 ccgaactcaa tcaaataaca ggtggagatt ggtggtcaga gatattaaat tttaatcgct
     1381 ctcaaaaata taaacatacc tccgtgggtt ctaataat
//
LOCUS       DARYXS010000175         1366 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.176, whole genome shotgun sequence.
ACCESSION   DARYXS010000175 DARYXS010000000
VERSION     DARYXS010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1366
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.176"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..361
                     /locus_tag="TV193_001950"
     CDS             <1..361
                     /locus_tag="TV193_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEL1514095.1"
                     /translation="RTRNNGIYLMLSDDELEILNKKYELSGCKSLRQFIMKCILEKDI
                     FVLDMKVFKEMSTNIGRITGSINQIAKRVNSTAVIYKDDINDLKKLLEKQGKDIYFLR
                     KKLYELGNFGTSGTEEI"
     gene            361..>1366
                     /locus_tag="TV193_001951"
     CDS             361..>1366
                     /locus_tag="TV193_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEL1514096.1"
                     /translation="MAVTKIHPIEKTLYLALDYIMNEDKTDEKILISSFGCNPKTAHL
                     EFEHTKKECNSKAKILARHLIQAFAPGETTPEQAHQIGLDLCERVLRGKYEYVLTTHI
                     DKGHLHNHILFNNVSFETGKAYQSNKRSYHQIRTVSDDLCRENGLSVIDENYKKFKNR
                     YSTNGKTYMEYTEFKKGNSWKNKLQLTIDKAVLKSKTYEEFLKTMEDFGYEIKIGKYL
                     SFRHKDKRDKGRFTRAKASTLGEDYTKERIKERIEDSNKQNIYVNQEYHYEKRSYKKP
                     DTIVDMKNNEKVKSSKGYEVWAGKHNMKTMASALNEMRKSGINSYEELDLKLKKVASD
                     R"
BASE COUNT          563 a          197 c          252 g          354 t
ORIGIN      
        1 cagaacaaga aataatggaa tataccttat gctttctgat gatgaacttg aaattttgaa
       61 taaaaaatat gaactgtccg gttgtaaaag tttaagacag tttattatga agtgcatcct
      121 tgaaaaagat atttttgtac tggatatgaa agtgtttaag gagatgtcta caaatatcgg
      181 aaggattaca ggtagcatca atcagattgc aaaaagggta aattcaactg ctgtaattta
      241 caaagatgac atcaatgatt tgaaaaagct cttggaaaaa caaggaaaag acatctactt
      301 tcttcgtaaa aagctatatg aattagggaa ttttggaaca agtggtacgg aggaaatcta
      361 atggcagtta caaaaattca tccgatagaa aaaacacttt atctagcatt agactatatt
      421 atgaatgaag ataaaaccga tgaaaaaatc cttatctcct cttttggctg caatcccaaa
      481 acagcccatc ttgaatttga acatacaaaa aaagaatgta attccaaagc aaaaatcttg
      541 gcaaggcatc taattcaagc cttcgctcca ggagaaacta cacctgagca ggcacaccaa
      601 atcggactgg atctatgtga gagagtcttg aggggaaagt atgaatatgt ccttacaaca
      661 catatcgaca aggggcatct acacaatcat attctgttta acaatgtcag ctttgaaaca
      721 ggaaaggcat atcaaagtaa taagagaagt tatcatcaaa tccgaacggt cagtgatgat
      781 ttatgtagag aaaatggctt gtcagttatt gatgaaaact acaaaaaatt taaaaacaga
      841 tactctacaa atggtaaaac ctatatggaa tataccgaat ttaagaaagg aaactcttgg
      901 aagaataaac tacaacttac tattgataaa gctgttttaa aatccaaaac ttacgaggaa
      961 tttctaaaga caatggagga tttcggttat gaaatcaaaa taggaaaata cctttccttc
     1021 cgacataaag ataaaagaga taagggaaga tttaccagag cgaaagcatc tactttaggg
     1081 gaagattata caaaagagag aatcaaggaa cgaatcgaag attcaaataa gcaaaatatt
     1141 tatgttaatc aggaatatca ttatgaaaaa cgctcctaca agaaaccgga tactattgta
     1201 gatatgaaaa acaatgaaaa ggtaaaatca tctaagggat atgaagtatg ggcaggtaaa
     1261 cataatatga aaactatggc atctgcctta aatgaaatga gaaaatcagg tattaactcc
     1321 tacgaggaat tagatttaaa attaaagaaa gtggcatcag atagac
//
LOCUS       DARYXS010000176         1318 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.177, whole genome shotgun sequence.
ACCESSION   DARYXS010000176 DARYXS010000000
VERSION     DARYXS010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1318
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.177"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(1001..1105)
                     /locus_tag="TV193_001952"
     CDS             complement(1001..1105)
                     /locus_tag="TV193_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1514097.1"
                     /translation="MTAFEVVQILLGFSSFTIALISLCYQIFKDDNKK"
BASE COUNT          448 a          216 c          240 g          414 t
ORIGIN      
        1 accagttaac tatatcaatc tatcaaaaaa aatatagtat gtcaacctct taaagtgatt
       61 taatcagaac aaacgtatga agaaaatcat ttggtgaaaa agaagcttat tttagctgaa
      121 atagatccat tataaaagag gtgtcgtgaa gtaactcaat attcacctat ttttgtcgca
      181 agtattctaa taggaataga aaaagggcag ttgcttgcaa caactaccca atgtaaaacc
      241 gttaaagacg gtgacagaaa ataactgtta actgaactac ctcaaaagtt aaaccaaaga
      301 tctaaccgtt ggatgttggt ttgtagagcg gttatttttt tattgttatg tttacaacga
      361 ctaagctcat cagtgtaagg gaaagggact tccatattaa gaagtatata tacatcctag
      421 atgagacgtg taatgaatgg gttgaacaaa tagttgctta attttgggat aagggttata
      481 ataaaaatag aaaaagggca gttgcttgca acaactaccc aatgcagaac cgtttgagac
      541 ggtggctggt tttatagtta aaagataacc gttaactcgc caaagttaag gacggttatt
      601 ttttattgtc atctttgaag atttgatagc acaagctgat aagcgcaata gtaaagctac
      661 taaagcctaa aaggatttat accacttcaa aagctgtcaa tgctttgact catcctttct
      721 gttagatttt gatgaactgc ccataggcct cacctacctt tcagaaataa gagccaccgt
      781 cttaaccttt ctgctttatc attatagcat attgttatta aggttgacta ttcagactcg
      841 tctaaagaag tgtaatagtt gcttaatttt gggataaggg ttataatgaa aatagaaaaa
      901 ggtagttgct cgacacaact acccatgcag aaccgtttaa gacggtggca tgttttatgt
      961 tattaaaaaa taaccgttaa ctcgccaaag ttaaagacgg ttatttttta ttgtcatctt
     1021 tgaagatttg atagcacaag ctgataagcg caatagtaaa gctactaaag cctaaaagga
     1081 tttgtaccac ttcaaaagct gtcaatgctt tggctcctcc tttctgttag attgtgatga
     1141 actgcccata ggcctcacct acctttcaga aataagagcc accgtcttaa cttttctgcc
     1201 tttttattat agcataccct atctctgatt gactagctta agaaggaggg gatgtgattt
     1261 ggatacaaat ttttgttaac ttttttaaag tctccaaatg atttaaaaaa atgatatt
//
LOCUS       DARYXS010000177         1307 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.178, whole genome shotgun sequence.
ACCESSION   DARYXS010000177 DARYXS010000000
VERSION     DARYXS010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1307
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.178"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..>1307
                     /locus_tag="TV193_001953"
     CDS             <1..>1307
                     /locus_tag="TV193_001953"
                     /inference="COORDINATES: protein motif:HMM:NF012873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514098.1"
                     /translation="RYSLDIDELPLTEIQSAYLLGRRNHFELGGVASHVYMEVILPLL
                     DIDRAEKVWNDIILKHDALHSIFTSNNTQKVLKEFAYYKIECNEGADIKEKIALTRDK
                     LKGKSYNADIWPLFDISVSQLDDNSLLHLSFDFLILDWASIWILLKEFEECYFDGKTI
                     MDNSYDLKEIRTSQLKLKHSSKYLSDKDFWERRIPFLPDAPLLPIKNKIVKNGFERIQ
                     LRIDENTWSKIKSNISEIGVTQTSFLVTILALVLNRWSSNSEFTINLTTMNRPKEYIK
                     SDVVNDFTSTELLEFRMESLQPFYVLLKHIQQQMIEDLQHETFTGVEVTREVRKNVER
                     RDAIFPFVFTSALGIKASEYKYISLQKEGLSETPQVLMDCQVMEVNHELIINFDLRAD
                     AFSKELSNSIAEDYSNLLNCFFDLEYFKKTLTEMYDENEMNDV"
BASE COUNT          499 a          150 c          233 g          425 t
ORIGIN      
        1 tagatattca ctagatattg atgaattacc tttaacagaa attcaaagtg catatttatt
       61 aggtagaaga aatcattttg aacttggtgg tgttgccagt catgtttata tggaagtaat
      121 attacctcta ttggatatag atcgagctga aaaggtttgg aatgatataa tactaaagca
      181 cgatgcatta cattcaatat ttacatcaaa caatactcag aaagtactga aggaatttgc
      241 ttactataaa atcgaatgca atgagggtgc agatataaaa gaaaaaattg cattaacaag
      301 ggataaactt aaggggaaaa gttataatgc agatatatgg ccactattcg atataagtgt
      361 aagtcagtta gatgacaata gtttattgca tttatcattt gattttttga ttttagattg
      421 ggcaagcatt tggattttat taaaggaatt tgaagagtgt tattttgacg gaaagacgat
      481 tatggataat tcttatgatc ttaaagaaat aagaacgagt caacttaaac tgaaacatag
      541 ttctaagtat ttatcggata aagatttctg ggaaagaaga attccttttt tgcctgacgc
      601 tccactatta ccaattaaaa ataaaatagt caaaaatggt tttgaaagaa tacaacttag
      661 aatagatgaa aatacttggt cgaagataaa atctaatata agtgagattg gtgtcacgca
      721 aacatctttc ttggtgacaa tattagctct tgttcttaat agatggagtt ctaattctga
      781 atttaccatt aatttaacaa ctatgaatag accaaaggag tatataaaga gcgatgttgt
      841 taatgatttt acatctacag aacttttaga gtttagaatg gaatctctgc aaccattcta
      901 tgttttatta aaacacatac aacagcaaat gattgaagat ttgcaacatg aaacatttac
      961 aggagtggaa gttactcgtg aagttaggaa aaatgtagaa aggagagatg ctatatttcc
     1021 atttgttttc acaagtgcat taggaataaa agcttcagaa tataaatata ttagtttaca
     1081 aaaagaaggt ttgagtgaaa ctcctcaagt attaatggat tgtcaagtaa tggaggtaaa
     1141 tcatgaacta ataattaatt ttgacttaag agcagatgct ttttcaaaag aattatcaaa
     1201 ttcaattgca gaagactatt ctaatctatt aaattgcttt tttgatttag aatatttcaa
     1261 aaaaacactg acagaaatgt acgatgaaaa tgagatgaat gacgttt
//
LOCUS       DARYXS010000178         1289 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.179, whole genome shotgun sequence.
ACCESSION   DARYXS010000178 DARYXS010000000
VERSION     DARYXS010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1289
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.179"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            54..485
                     /locus_tag="TV193_001954"
     CDS             54..485
                     /locus_tag="TV193_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1514099.1"
                     /translation="MDLTVQNKDLNTLYSVLDKIKVTNMRVNRGRAKLLAKVEAKLRE
                     YAKDEVDIIDQYAAKNDKGKWLVDDKGNAKLADVTKAAELNELLDELANEPIVIKGHE
                     YSKRFIDFLEYLAEAEDEFTGAEIILIDNVLEQYEANKKGE"
     gene            489..1100
                     /locus_tag="TV193_001955"
     CDS             489..1100
                     /locus_tag="TV193_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1514100.1"
                     /translation="MRNWKIIGKYPQPNALGVIEGTHVIITGDDGASIPQTIKKDLSS
                     TNDFEVIKMVLDEFKKSEYVEIAMGEAVQKVDDLEKLSQETAKTATTAQTAAGLARAA
                     AERTQKMINLQTIHVLTTSDKVEPDIYKGMLELIAPAKKGQYQEHDVFTVLDDKHEDL
                     AGEGNLVFVYVNEPFEYDKQTLKDLESEDKVTVIKYADLVKQD"
     gene            1111..>1289
                     /locus_tag="TV193_001956"
     CDS             1111..>1289
                     /locus_tag="TV193_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514101.1"
                     /translation="MIDFVQIGAFCGAALSILGVWGFIVNPFKKAMEANELAMAQLKD
                     SIKELAYELKNLDRD"
BASE COUNT          433 a          248 c          306 g          302 t
ORIGIN      
        1 agtgcaatca tcagagagta taactcatat attaatggat tataggagac aacatggatt
       61 taacagtaca aaacaaagac ttaaatacgc tctatagcgt actagacaaa attaaggtta
      121 ctaacatgag agttaatcgc ggccgcgcta agctgcttgc caaagtcgag gctaagctaa
      181 gagagtacgc taaggacgag gttgatatta ttgatcagta cgctgctaaa aacgacaaag
      241 gcaagtggtt ggtcgatgac aaaggcaacg ctaaattagc tgatgtcaca aaagcagctg
      301 agctaaacga gcttttagac gagttagcca acgagcctat cgtcatcaaa ggccatgagt
      361 actctaagcg atttatcgac tttttggagt acttggccga ggccgaagat gagtttacag
      421 gggccgaaat catcttaatc gataatgtct tagagcaata cgaagcaaac aaaaaaggag
      481 agtaaattat gcgcaattgg aaaatcatcg gcaaatatcc acaaccaaac gcgctagggg
      541 ttattgaggg tacacatgtc atcatcacag gtgatgacgg tgcatctatc ccgcaaacga
      601 taaaaaaaga tctgtcatct acaaatgatt ttgaggtcat taaaatggtc ctcgacgagt
      661 ttaaaaaatc agagtatgtc gaaatcgcaa tgggcgaggc agtccaaaaa gtggacgact
      721 tggaaaaact atcgcaagaa actgctaaga cagcaacaac tgcacaaaca gccgctggtt
      781 tggccagggc agctgcagag cgcacacaaa agatgattaa cttgcagact atccacgttt
      841 tgacaaccag cgataaagtc gagcctgaca tctacaaagg catgcttgag cttattgcgc
      901 cggccaaaaa agggcaatat caagagcatg atgtctttac ggtgctagac gacaagcatg
      961 aggatcttgc aggcgagggc aatctcgtct ttgtgtatgt caacgagccg tttgagtatg
     1021 acaaacaaac gctcaaagac ttggagtctg aggacaaagt cacagtcatt aaatatgcgg
     1081 atttggtaaa acaagattag aggtggttag atgatagatt ttgtacaaat tggtgctttt
     1141 tgtggcgctg ctttgtctat cttgggtgtt tggggattta tcgtcaatcc ctttaaaaaa
     1201 gccatggaag ctaacgagct agccatggcc caactcaaag actcgatcaa ggagttagcc
     1261 tacgagctaa aaaatcttga tcgcgatag
//
LOCUS       DARYXS010000179         1288 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.180, whole genome shotgun sequence.
ACCESSION   DARYXS010000179 DARYXS010000000
VERSION     DARYXS010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.180"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            85..1288
                     /locus_tag="TV193_001957"
                     /pseudo
     CDS             85..1288
                     /locus_tag="TV193_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISSeq1 family transposase"
BASE COUNT          392 a          309 c          242 g          345 t
ORIGIN      
        1 gggttatagg gctttatgag tatcaaaaaa gtcccatatg acctataatg aaaagcgact
       61 aaactatcat ttagaaagac tcatatggaa caatcacatg ttatcacaca actactggga
      121 attaaagacc ctcatatcac attctccaaa gaaatacacg acatgaaaac tcataaggaa
      181 ttgaaagctg tccttgacta cgatgcccca ccttgcccta actgccaaag tcagatgggc
      241 aagtacgact tccaacggga atccaaggtc ccttttctcg attgcgcagg ctacaagact
      301 ttgattcgcc tcaaaaagcg ccgtttcaaa tgtcagtttt gcggaaaaat tactgtcgct
      361 gagacttctc tagtccctaa aaaccatcaa ataccaacca tcgtcaaaca gaaggtggcc
      421 cagcttctca tcgagaaagt ctccatgacc gctatcgctg atagactatc catctccacc
      481 tcaaccgtca tgcgaaagct caacgagttc acgttcaagt ctcatttgac ttatttaccc
      541 gaacatatgt cctgggatga atatgccttt aagaagggca agatgagctt tattgctcag
      601 gactttgaca ccaacaacat catcgctatt ttggatggac ggacgaaagc tgtcattcgc
      661 aaccacttcc tgagatatcc tcggcaggtc agaaacgacg ttaaactcat caccatggat
      721 atgtttaccc cctattacaa cctggctaag atgcttttcc caaacgctta gattgtcctt
      781 gatcgtttcc acattgtgca acatttggga cgtgccatga accgtatccg tactcaaatc
      841 atgaactctt ttgatcgaaa atcccacgaa tacaaggctt tgaaacgtta ctggaagctg
      901 attcaacaag atagtagcaa acttagtgac aagcgttttt accgcccgac ttttcgcatg
      961 catttgacaa acaaggaggt ggtcgagcgt cttttgagct actctgacga gcttagaaag
     1021 cattatgacc tttatcagct tctgcttttt cacttccagg aaaagcaagc tgaccacttt
     1081 ttcggcctga ttgaggagca gatagacagt agcaatcctc tctttcagac cgttttcaag
     1141 acctttttga aagacagaga caagattgag aacgcactgg atttgcctta ttctaacgct
     1201 aaactggagg ctaccaataa tctcatcaaa gtcatcaagc gcaatgcttt tggatttcgg
     1261 aactttgaaa actttaaaag acggattt
//
LOCUS       DARYXS010000180         1285 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.181, whole genome shotgun sequence.
ACCESSION   DARYXS010000180 DARYXS010000000
VERSION     DARYXS010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1285
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.181"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            241..1200
                     /locus_tag="TV193_001958"
     CDS             241..1200
                     /locus_tag="TV193_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1514102.1"
                     /translation="MKLEKGDIVKTALSENTTVLDVKDNQAVLFSGTQFVLATGIKEN
                     KESGKFEWDNGRYANDLKSISDIQNNNFETMKETLSFLAEYNHSDFVKGILSLETGIE
                     NEDTLDAAYDNYMNDKIMGLVDEKFYHYIDENEIEAPDLESEIQDKNSVLSDEENVKE
                     DNNTTSEKSNENKEKANTVNINGNIASDIDIKNLTSKDGRDFTVASFAVAENDKEGNV
                     KYTNCLAYNDKVSSVENLKKGDFVHVFGKEKISQGKDGKEYTSLKVYSAKLLKAKEQS
                     KTNQNAKDVKKPSALGKLKEYKEKAGEKSKEQVSVKKDKNIER"
BASE COUNT          553 a          126 c          262 g          344 t
ORIGIN      
        1 actaaaatga aaaataaggt atacgaattt aatcaaaaaa aatatccggg ttatgaggat
       61 atggatataa aactaacaat atctactatt aagggtatcg aggatttcga tacccttaat
      121 gatttttatg atagtttgaa aaggaaggga tatttagaag cgataaaaga aagtattaaa
      181 aatattattg ataaagaatt agaagaaaac atacaagtaa aagtacagga ggtaaaaaat
      241 atgaaattag aaaaaggcga tattgtaaaa acagcattaa gtgaaaacac aacagttttg
      301 gatgtgaaag ataatcaggc ggtactgttt tcaggtactc agtttgtact tgcaacaggg
      361 attaaagaaa acaaggaaag cggaaaattt gaatgggata atgggcgata tgcaaatgat
      421 ttaaaaagca tttccgatat acaaaacaat aattttgaaa cgatgaaaga gaccttatct
      481 tttttagcag agtataatca tagcgatttt gtcaaaggaa ttctgtctct tgaaacagga
      541 atagaaaatg aggatactct tgatgctgct tatgataatt atatgaatga taaaattatg
      601 ggtttggttg atgaaaaatt ttatcattat atagatgaaa atgagattga agcacctgat
      661 ttagaaagcg aaatacagga taagaatagt gttttatccg atgaggaaaa tgtaaaggag
      721 gacaataata ctacgagtga gaagtcaaat gaaaataagg aaaaagcaaa tactgtaaat
      781 atcaatggca atattgcttc agatatagac attaaaaatt tgacatcgaa agatggtaga
      841 gattttactg ttgcaagttt tgcagttgct gaaaatgaca aggagggaaa tgtaaaatat
      901 accaactgtt tagcctataa cgataaggta agtagtgtag aaaatttgaa aaaaggagat
      961 tttgttcatg tattcggaaa agaaaaaatc agtcagggaa aggacggaaa ggaatataca
     1021 tctcttaaag tttattctgc aaagctgtta aaagccaaag aacagagcaa aacaaatcaa
     1081 aatgcaaagg atgtaaagaa accgtcagca cttggcaagt taaaagagta taaggaaaag
     1141 gcaggcgaaa aatcaaagga acaggtcagt gtcaaaaaag ataaaaatat agagagataa
     1201 aattataaaa atagtgggta aatagctgat agggctgttt atccactatt tttctttgtt
     1261 tttttattag aaatggaaaa ataaa
//
LOCUS       DARYXS010000181         1264 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.182, whole genome shotgun sequence.
ACCESSION   DARYXS010000181 DARYXS010000000
VERSION     DARYXS010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1264
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.182"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..>1264
                     /locus_tag="TV193_001959"
     CDS             <1..>1264
                     /locus_tag="TV193_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1514103.1"
                     /translation="IKTEEEYFDEDTYTEQNSKENEQDWQREQEILLIQDEREVSYEE
                     AEEIYERQAEIEHNAFATGVENNISSTQSNKDYWIVEFNEGSNLIEKNYAGEVVTKKL
                     LDEIKVLDEKIRVHNKTVGEDEYGEMTDEWVGYSKFYFDHIVDGKVEEHFRMDIGDGN
                     EVNQRDFQYLYEQIEPEKENKEYGMDSIDSVIKDILEKESMTVVSSKDDYIKLFPYFR
                     NFVYTDGLRLDEYNPFEDDENISDLIRLTFFQNNDGEYRVVYNNADSLLYSSNVDYFL
                     EKIEAEKVRLEDNIAEIPNEDKIAVKVGNYYAVVEKERVKDISLEETGVRVYPKENNF
                     EGKIYPLYRGSTFEESAKIDKLFDEIAIGMKEVNLTDLNDVFYLENQGLYEISSDRVT
                     EEKAGYDFEVASFNEQFPDYYNDIYVYN"
BASE COUNT          498 a          136 c          279 g          351 t
ORIGIN      
        1 gcataaaaac tgaggaagaa tattttgatg aagataccta tacggaacaa aactctaaag
       61 aaaatgaaca agattggcaa agagaacagg aaattttgct gattcaagat gaaagagaag
      121 tatcttatga agaggcggag gaaatatatg aaaggcaagc agaaatagaa cataatgcct
      181 ttgcaaccgg tgtagagaat aacatatcgt caactcaaag taacaaggat tattggattg
      241 tagaatttaa tgaaggctca aatctgatag aaaaaaatta tgccggagaa gttgttacga
      301 aaaaattgct tgatgaaatc aaggtgcttg acgaaaaaat tagagttcat aataagactg
      361 tcggtgaaga tgaatacgga gaaatgacag atgaatgggt aggttattct aaattctatt
      421 ttgaccatat tgtagacggg aaagtagaag aacacttcag aatggatatc ggggatggaa
      481 atgaggtaaa ccaaagagat tttcaatatc tttatgagca gattgaaccg gaaaaagaaa
      541 ataaagaata cgggatggat agtatagata gtgtcataaa agatatttta gaaaaagaat
      601 ctatgactgt ggtatcaagc aaagatgatt atataaagtt atttccatat tttagaaact
      661 ttgtatatac cgatggtcta aggcttgatg aatataatcc gtttgaagat gatgaaaata
      721 tttcggattt aattcgactg acttttttcc aaaataatga tggagaatat agggtagtct
      781 ataacaatgc ggacagttta ctgtattcaa gcaatgttga ctattttttg gagaaaatag
      841 aggctgaaaa ggtaaggtta gaagataata tagctgagat accgaatgaa gataaaattg
      901 ccgttaaggt tgggaattac tatgctgttg tagaaaaaga aagagtaaag gatatatcct
      961 tagaagaaac aggagttcgt gtttatccga aagaaaataa ctttgaggga aaaatttacc
     1021 cattgtatcg tggcagcacc tttgaagaaa gtgcaaaaat agataaactt ttcgatgaga
     1081 ttgcaatagg catgaaagag gtcaatttga ccgatttaaa tgatgttttt tatcttgaaa
     1141 atcaaggact ttatgaaatt tcatcggata gggtaacgga agaaaaagcc ggatacgatt
     1201 ttgaagtggc aagttttaat gaacagtttc ctgattacta taatgacatt tatgtatata
     1261 acag
//
LOCUS       DARYXS010000182         1245 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.183, whole genome shotgun sequence.
ACCESSION   DARYXS010000182 DARYXS010000000
VERSION     DARYXS010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1245
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.183"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(32..1213)
                     /locus_tag="TV193_001960"
     CDS             complement(32..1213)
                     /locus_tag="TV193_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1514104.1"
                     /translation="MTKRLLLFVLVCLCFLGISQVHAEDVMEITRKAGYTVSEVNRPK
                     ASIVVDAKTSEILWQDNIDMPRDPASMSKMFTLYILFEELAKGKVTLDTTITATETDQ
                     AISKIYEISNNNIVAGVAYPIRDLIIMTVVPSSNAATVMIANYLSNNDASAFIDRINK
                     TAKELGMTNTHFSNASGAIAQAFQGYYLPEKYDLTASNITTARDFATLIYYFLTNYPS
                     ILDFTNQTVVRTMVGTPYEEEFHSYNHSLPDGKFGIEGVDGMKTGSSPSAAFNAVVTA
                     KRGNTRLITVVLGVGDWSDQNGEFYRHPFINALTEKAFKDSKTLTKAKRSKLKRLAAK
                     PASTAAAAKKQLPQATTDQSFLEKIEQFVDDHRPLVLICLAIFILIVLLLALMAFMMG
                     R"
BASE COUNT          362 a          241 c          263 g          379 t
ORIGIN      
        1 taccaagaag tctttttaat cagcaatgag cttaacgtcc catcataaag gccatcagag
       61 caagtagtaa aacaataagg ataaaaatgg ctaagcaaat caagacaagg ggacgatgat
      121 catcgacaaa ttgttctatt ttttcaagaa atgattgatc agttgtggct tgtggcaact
      181 gctttttggc agctgctgct gtgctggctg gtttagcagc aagcctttta agcttgcttc
      241 gttttgcttt ggtgagtgtt ttactatctt taaaggcttt ttcagtcaaa gcattaatga
      301 atgggtgacg gtaaaattct ccattttggt cagaccaatc accaactcct aggacaactg
      361 taatcagtct ggtatttcct cgttttgctg ttacgaccgc attgaaagca gcacttgggc
      421 tggatcctgt tttcatacca tcaacaccct ctattccaaa cttaccatca ggcagagagt
      481 ggttgtagga atggaactct tcctcataag gggttccaac catggtgcgg acgacagttt
      541 gattggtaaa atcaagaata ctaggataat tggtcaaaaa ataataaatt aaggttgcaa
      601 aatcacgtgc tgttgtgata ttagaagctg ttaaatcata tttttctggg agatagtagc
      661 cttgaaaggc ttgtgcgatt gctccgctag catttgaaaa atgcgtatta gtcatgccga
      721 gctctttggc tgttttgttg atccgatcaa taaaggctga cgcatcgttg ttggataggt
      781 agttggcaat catcactgtt gcagcatttg atgacggaac cactgtcata atgattaaat
      841 cacgaatagg gtacgcaact cctgcaacaa tattattatt gctgatttcg taaattttac
      901 taatcgcctg atcagtctct gttgctgtaa tggtggtatc aagtgttacc tttcctttgg
      961 ccaattcctc aaagaggata taaagcgtaa acatctttga catactagca gggtctctag
     1021 gcatgtcaat gttatcctgc cataagatct ctgaggtctt tgcgtcaaca acaatggagg
     1081 cttttggcct attaacctca ctaacggtat agccagcctt gcgggtaatt tccatgacat
     1141 cttcggcgtg aacctgagaa atgcctagaa agcacaggca caccaaaacg aatagtagca
     1201 atcttttagt caattcaaag ctccttaatg taaaaaaata atgta
//
LOCUS       DARYXS010000183         1235 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.184, whole genome shotgun sequence.
ACCESSION   DARYXS010000183 DARYXS010000000
VERSION     DARYXS010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1235
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.184"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(170..1219)
                     /locus_tag="TV193_001961"
     CDS             complement(170..1219)
                     /locus_tag="TV193_001961"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515503.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1514105.1"
                     /translation="MKTIAYPNKPHSLSAGLLTAIAIFSLASSNITYADDYQRNATEA
                     YAKEVPHQITSVWTKGVTPLTPEQFRYNNEDVIHAPYLAHQGWYDITKAFDGKDNLLC
                     GAATAGNMLHWWFDQNKTEIEAYLSKHPEKQKIIFNNQELFDLKAAIDTKDSQTNSQL
                     FNYFRDKAFPNLSARQLGVMPDLVLDMFINGYYLNVFKTQSTDVNRPYQDKDKRGGIF
                     DAVFTRGDQTTLLTARHDLKNKGLNDISTIIKQELTEGRALALSHTYANVSISHVINL
                     WGADFNAEGNLEAIYVTDSDANASIGMKKYFVGINAHRHVAISAKKIEGENIGAQVLG
                     LFTLSSGKDIWQKLS"
BASE COUNT          357 a          239 c          244 g          395 t
ORIGIN      
        1 tatctagttt acttatctta gaaaagaaca acaggcacat taatgtttaa caaaacaaga
       61 gcttaaagag ttcatgacaa gctttaacca atgacagtga gctaataggg ctattgttag
      121 acgaaaaaac agaccaataa gcacttggtc tgttcctaat gatgactggt tagctcagtt
      181 tctgccatat gtccttgcca ctggaaagcg taaataagcc taatacttga gcgccaatgt
      241 tttctccttc tattttcttg gcagaaatgg cgacatgtct atgagcatta atgccgacaa
      301 aatatttttt cataccaata gacgcattag catctgagtc tgtgacatag atggcctcaa
      361 ggtttccttc agcattaaaa tcagctcccc acaagttaat cacatggcta atgctaacat
      421 tggcgtaggt atgtgataaa gcaagggctc ttccttcagt cagttcttgc ttgataatgg
      481 tgctgatgtc atttagtcct ttatttttta aatcatgacg agctgtcaag agcgttgtct
      541 gatctcctct ggtgaaaaca gcatcgaaaa taccacctcg tttgtccttg tcctgataag
      601 gtcgattgac atcagtagac tgtgttttaa acacatttaa gtagtaacca ttgataaaca
      661 tgtctagaac aagatcaggc ataaccccga gttgacgtgc tgatagattt ggaaaggctt
      721 tatctctaaa ataattaaaa agctgactat tggtttgact gtccttggta tcgatagcag
      781 ctttcaaatc aaatagctct tggttgttaa aaatgatttt ttgcttttca gggtgtttac
      841 ttaaataggc ttcaatctct gttttatttt gatcaaacca ccaatgcagc atattacctg
      901 ccgttgctgc gccacacaag agattatcct tcccatcgaa ggccttggtg atatcgtacc
      961 agccttgatg agcaagatat ggcgcatgga tcacatcttc gttattatat cgaaactgct
     1021 cgggtgttag tggtgtaaca cctttggtcc atacagaagt gatctgatgt ggtacttctt
     1081 tggcataagc ttccgtagca ttcctttggt aatcgtcagc ataagtaatg tttgaactcg
     1141 ccaggctaaa aatagctata gcagttaaga gaccagctga taaggagtga ggtttatttg
     1201 gataagctat tgttttcata taaccctttc ttgtt
//
LOCUS       DARYXS010000184         1200 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.185, whole genome shotgun sequence.
ACCESSION   DARYXS010000184 DARYXS010000000
VERSION     DARYXS010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1200
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.185"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..242
                     /locus_tag="TV193_001962"
     CDS             <1..242
                     /locus_tag="TV193_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1514106.1"
                     /translation="NGMLKISVINDVSPNLNVNWNMVTSKFYRGDLSRRISNNGSGLG
                     LTIVNDIVKHLGGNFEIGEENKRVCAKVILPYRLN"
     gene            520..903
                     /locus_tag="TV193_001963"
     CDS             520..903
                     /locus_tag="TV193_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEL1514107.1"
                     /translation="MKKALSLVLLTGLMLASSVPAFAAEETNLPYVEGLGYEVEVFEE
                     DYTQPKLFSYDSGWKSFLGGKWRHGVGSRYVWSKYDHNNKTHKTTVQGAGGQFSYSGW
                     TSAGSRAEASWEKALSGNRAWADVK"
     gene            1011..>1200
                     /locus_tag="TV193_001964"
     CDS             1011..>1200
                     /locus_tag="TV193_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514108.1"
                     /translation="MKKTVGILAILLIIVIGIGKFFYSDGMFLNIFIKEFNTTVNIVT
                     KPEIADKTIIELQKIANKN"
BASE COUNT          450 a          122 c          255 g          373 t
ORIGIN      
        1 taaatggaat gttaaaaata agtgttataa acgatgtttc tccaaattta aatgtgaatt
       61 ggaatatggt tacttcaaag ttttataggg gagatttatc aagacgaata agcaataatg
      121 gatcgggact tggacttaca attgtaaatg acattgtaaa acacttgggt ggaaattttg
      181 aaattggaga ggagaataaa agagtttgtg ctaaagtaat acttccatat agattaaatt
      241 aaatcgcaaa gaaaacgcaa gaattattca aagataccgt taagtataaa gcaaagagct
      301 attctataat gtgagtaagg atagctcttt tatatttgaa aggaattatt aatttgaata
      361 agcatctgtg attataaata tataaaatgg aggtggagtt ttatgaatta caataatcct
      421 cataggtata ggaacggaga ttgagtagag ttttgggaaa ctttattcgg aagaaaaatt
      481 ttacaaaaaa tttaagtatt tgagagagga gaatttatca tgaaaaaagc attgtcatta
      541 gtattattaa caggtttgat gttagcatca tctgtaccag catttgcagc agaagaaaca
      601 aacttgccat atgttgaagg tcttggttat gaggtggaag tatttgaaga agattatact
      661 cagccaaagt tgttcagtta tgatagcgga tggaaaagtt ttttaggtgg aaaatggaga
      721 catggtgtag gtagtcgata tgtttggtct aaatacgatc acaataataa aacacataaa
      781 actacagtac aaggtgctgg tggtcaattc tcttattcgg gttggacaag cgctggaagt
      841 agagcagaag cttcttggga aaaagcttta agtggtaata gggcttgggc tgatgttaaa
      901 taacaataaa taaaaaatag ttgaacgagt ttgagcggtg ccacgttgtt attttagcat
      961 tgtggcatta ctcatactcg ctatttttat aaagttggag atgatacaga atgaaaaaaa
     1021 cagtgggtat attggcaatt ttactaatta tagtgattgg tataggaaag tttttctatt
     1081 cagacggcat gtttttaaat atattcataa aagagtttaa tactactgta aacattgtaa
     1141 caaagccaga aatagctgat aaaacaataa ttgaattgca gaaaatagct aataaaaatg
//
LOCUS       DARYXS010000185         1174 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.186, whole genome shotgun sequence.
ACCESSION   DARYXS010000185 DARYXS010000000
VERSION     DARYXS010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1174
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.186"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            5..1156
                     /locus_tag="TV193_001965"
     CDS             5..1156
                     /locus_tag="TV193_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1514109.1"
                     /translation="MSKNFKNSLVKIAIAALASFAVITIPTYQHSVISAKTVSVNQTY
                     GEYKDYYTVIGESNIDKSTFPEIYKTTERVYKGQGTSEKRVTVSDVVYNPLDGYKRST
                     GAYGVVTKDMIDMSKGYREKWETNPEPSGWFRFYNRADHEEISEKEYDSRRTKSYKVT
                     NNVPVVLTTLKGKKYNSHLFVRSHLFADSLGGKSIRKNAITGTQMQNVGTRKGGMQYI
                     EKKVLSHITKNPDVYVFYSAIPEYQGTELLARSVLVSALSSDGVINETVRVFNTADGF
                     NIDYQKGGLLSPTADVDTNNTEENVENETETTKDEVESEVDINTVKEDDENISLQNTV
                     YVASNGQSNVYWYSKENMPKNVNLDKVVEMSEQTALARGKHHSTQENIE"
BASE COUNT          446 a          193 c          219 g          316 t
ORIGIN      
        1 tgatatgtct aaaaatttca aaaactctct cgtcaaaata gctattgcag cacttgcatc
       61 atttgctgtg ataactatac caacttatca gcacagcgta atctcagcta aaacggtctc
      121 ggtaaatcaa acttacggtg aatataaaga ctactacact gtaattggtg agtcaaatat
      181 tgacaaatcg actttccctg aaatatataa gaccactgag agagtctata aaggacaagg
      241 tacaagcgag aaaagagtaa cagtctctga tgtagtttat aacccattag atggctataa
      301 acgttcaaca ggcgcctacg gcgttgtcac aaaagatatg attgacatgt ctaaaggata
      361 tcgtgaaaaa tgggaaacca atcctgaacc aagcggttgg ttcagatttt ataatagagc
      421 tgatcatgaa gaaattagtg agaaagaata tgattcaaga cgtactaaat catataaagt
      481 tacaaataat gtacctgtag tgctaacaac attaaaaggt aaaaaataca acagtcattt
      541 atttgtacgt agccatctct ttgctgatag tcttggagga aagtccatac ggaaaaatgc
      601 tattactgga actcaaatgc aaaatgtagg aacacgtaaa ggtgggatgc aatatattga
      661 gaaaaaagtt ttaagccata tcactaaaaa tcctgatgtt tacgtattct acagtgccat
      721 tcctgaatat cagggtactg aattattggc aagatcagtt ttagtatctg ctttatcttc
      781 cgatggagta attaatgaaa ctgttcgtgt tttcaatacc gctgatggat ttaatattga
      841 ttaccaaaaa ggtggactct tatcccctac tgctgacgta gatactaata acaccgaaga
      901 aaatgtagaa aatgaaaccg aaactactaa agatgaggtc gaaagcgaag ttgacattaa
      961 tacagtaaaa gaagatgatg aaaatatttc tttacagaac actgtatatg tggcaagcaa
     1021 tgggcaatct aatgtatatt ggtacagcaa ggaaaatatg cccaaaaatg taaatttaga
     1081 caaagttgtg gaaatgagtg aacaaaccgc tttggctaga ggtaagcacc attccactca
     1141 agaaaatata gaataacaaa tctaacaaac caac
//
LOCUS       DARYXS010000186         1155 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.187, whole genome shotgun sequence.
ACCESSION   DARYXS010000186 DARYXS010000000
VERSION     DARYXS010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1155
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.187"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            9..>1155
                     /locus_tag="TV193_001966"
     CDS             9..>1155
                     /locus_tag="TV193_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1514110.1"
                     /translation="MNKKIIFKGDQDSKFAYFSLMFSAGTAIENTEELGFSHLIEHLL
                     LRSGGEQSLNELFDNNGAFIGGETSRDYINLMGYCKAENFKNIFEAIVSRVFNLNLTE
                     EELLREKRVVLVELTQYENGSKTEKLVSDNRLIFKNSKWSEDIIGVRENIESVDLKKL
                     YKFYTENIQNGEFQIAISGPNHLKEEIAIIENKLPVGRTPVKSNFPIFSSGVTERKKN
                     QQVSEISMYIDISKMTTSSHDVAILTILNAMLTGVKGSVLGGKLRTKNQWVYNIISFP
                     IFYNGLTILKILTRTPEIHKHQVVQVLKEDLVNREDLKNTKLFDKAKKRVINEVLMSY
                     EVKKVEFLKTLCREKLFNIPSWESVTGEIEKVSLNELNQFAKDALMQN"
BASE COUNT          449 a          132 c          214 g          360 t
ORIGIN      
        1 aaaaatagat gaataaaaaa attattttta aaggtgatca agatagtaaa tttgcttatt
       61 tttcattgat gttttctgca ggtactgcca ttgaaaatac agaagaactt ggtttttcac
      121 atttgataga gcatttatta ttacgatcag gcggagaaca atcattaaat gaactatttg
      181 ataataatgg tgcatttatt ggaggtgaaa cttctagaga ttatattaat ttgatgggtt
      241 actgtaaggc tgaaaatttc aaaaatatat ttgaagcaat agtaagtagg gtatttaatt
      301 taaatcttac tgaagaagaa ctgctaagag aaaaaagggt agttttagtt gaactaacac
      361 agtacgagaa tgggagcaaa acagaaaaat tagtttcgga taaccgccta atttttaaaa
      421 atagtaagtg gtcagaagat attattggtg ttagggagaa tattgaatct gttgatttga
      481 aaaagcttta taagttttac actgagaata tccaaaacgg agaatttcaa attgctattt
      541 caggaccgaa tcacttaaaa gaagaaatag cgattattga aaataaatta ccagttggaa
      601 gaactcctgt taaatctaat tttcctattt tttctagtgg tgtaacagaa cgaaagaaaa
      661 atcaacaggt ttctgaaatt tcaatgtata ttgatatttc aaaaatgaca acatcatctc
      721 atgatgtagc gatattaaca attttaaatg cgatgttaac aggagttaag ggttcagtgt
      781 taggaggtaa attaaggacg aaaaaccaat gggtatataa tataatttca ttcccaatct
      841 tttacaatgg gctcactatc ctaaagatac tgactagaac gcctgaaatt cataagcatc
      901 aagtagtaca agttctaaaa gaagacttag taaatagaga agacttaaaa aatacgaaat
      961 tatttgataa agctaaaaaa agagttatca atgaagttct tatgagctat gaagtgaaga
     1021 aagtcgagtt tttaaagaca ctttgcaggg agaaattatt taatatacct agttgggaga
     1081 gtgttactgg ggaaattgag aaagtttctc tcaatgaact taatcaattt gctaaagatg
     1141 ctctcatgca aaaca
//
LOCUS       DARYXS010000187         1143 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.188, whole genome shotgun sequence.
ACCESSION   DARYXS010000187 DARYXS010000000
VERSION     DARYXS010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1143
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.188"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..233)
                     /locus_tag="TV193_001967"
     CDS             complement(<1..233)
                     /locus_tag="TV193_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1514111.1"
                     /translation="MKTLLKLIVFIVGALVLILGMEVKHRMDIYDQVKQVELKNAHSK
                     EAIDIYEKKLKRLDPQALTDEGLIKSYTIDSDST"
     gene            complement(230..631)
                     /locus_tag="TV193_001968"
     CDS             complement(230..631)
                     /locus_tag="TV193_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1514112.1"
                     /translation="MKTLLKLIVFIVGTLVLMLGMEVKHRMDTYDQIKQVELKNAHSK
                     EVIEMYEQELISMDPQALTDEGLIKSYTIDSDSLFINPMGGFSIHLIINDDPDIYLRV
                     GLGRYDMERNLEIDGIYRSEKLEKLLKGVER"
     gene            complement(706..1098)
                     /locus_tag="TV193_001969"
     CDS             complement(706..1098)
                     /locus_tag="TV193_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1514113.1"
                     /translation="MNRFLKISLLIVGVIVIMLGMEVKHRMDIYDQIKQEEIKIAQSK
                     EAIVIYEQELKWLDPNALTNEGTIKSYSIDLDSITLNPMGGFSIALHINKNPKYKYRI
                     SLMWNTPMRDLCVGGSSLSPELQELLDR"
BASE COUNT          334 a          236 c          158 g          415 t
ORIGIN      
        1 gttgagtctg agtcaatagt ataagacttg ataagccctt catctgttag ggcctgagga
       61 tccaatcttt ttaacttctt ttcataaatg tctatcgctt ctttactatg cgcgtttttg
      121 agttctacct gtttgacttg atcgtatata tccattctat gctttacctc catgccaaga
      181 ataagtacaa gggcaccaac aataaataca ataagtttta acaatgtttt catctctcca
      241 ctccttttag tagtttttct aacttttctg agcgatagat accatcaatc tccaaatttc
      301 tttccatatc atatctacca aggccaactc tcaagtaaat atctggatca tcattgataa
      361 ttaaatgaat ggaaaagcct cccatcggat taataaagag tgaatctgag tcgatagtgt
      421 aggacttgat aagtccttca tctgttaggg cctggggatc cattgatatt agctcctgtt
      481 catacatttc aatcacttct ttactatgcg cgtttttgag ctctacctgt ttgatttgat
      541 cgtatgtatc cattctatgc tttacctcca tgccaagcat aagtacaaga gtaccaacaa
      601 taaatacaat gagttttaac aatgttttca taactatgct ccttttcatg aaaattatat
      661 tgttctttgg tgcaatcaat tgtttctgat agcctgtcat aatcattacc tatctaacaa
      721 ttcttgtaat tctggcgaca aagaggatcc tcccacacat aaatctctca ttggtgtatt
      781 ccacattaaa cttattcgat acttatactt tggatttttg tttatatgta aagcaatgga
      841 aaagcctccc attggattaa gagttattga gtctaaatca atagaatagg atttaatagt
      901 cccttcattt gtcaatgcat ttgggtccaa ccattttaac tcctgttcat aaatcacaat
      961 tgcttcttta ctttgggcaa tttttatctc ctcctgcttg atttgatcgt atatatccat
     1021 tctatgcttt acttccatgc caagcataat gacaataaca ccaacaataa gcagactgat
     1081 ctttaaaaac ctattcatgt ctatactcct atatcattcc tatacttatc gataaattcc
     1141 caa
//
LOCUS       DARYXS010000188         1126 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.189, whole genome shotgun sequence.
ACCESSION   DARYXS010000188 DARYXS010000000
VERSION     DARYXS010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1126
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.189"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(1..585)
                     /locus_tag="TV193_001970"
                     /pseudo
     CDS             complement(1..585)
                     /locus_tag="TV193_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407284.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            complement(872..1006)
                     /gene="rpmH"
                     /locus_tag="TV193_001971"
     CDS             complement(872..1006)
                     /gene="rpmH"
                     /locus_tag="TV193_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEL1514114.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
                     "
BASE COUNT          274 a          302 c          201 g          349 t
ORIGIN      
        1 aatcttgccc tcagctatca ctgatacccc tgcatcacac aaggcactta tcagctccat
       61 atccggacct gtcccctgac gactataggg cgtataccct gataaggtcg tccctacaaa
      121 atctatacca gcctcatagg ctgctagacc ctattcaagc gtactgatgt ctgccataaa
      181 cagctgctct gggtacttct cccttatcgc tcgaataaaa tccactatcg ctaagccatc
      241 atgacgctcc ctttgcgtac aatccaaggc tatcaccgct acacctaagg ccgctaaggc
      301 atctacctct gccatggttg gcgtgataaa gggcgcttgc ggaggatact cctttttgat
      361 gatccctatg attggcagat ccgtcaccgc ttggatttcc ttaatatctc gaaccccatt
      421 agctcttatc cctactgctc ctgcttcctc tgctgccttt accatcagag gcatgatacc
      481 tcctgcctct gaatagagag gctcgcccgg cagagcttga caggaaacga tcagcccgtc
      541 cttcagagct gccagtagct ctgccttgct tggtttttca agcatgcttt ctactccttt
      601 tattaatttt agagaacgtt cacatcttta ttgtagcaga tattaaagcg ttttcaatac
      661 ttcctctggt tttagaaact actttcattt ttagccctat ttccgttatt tttgaaaacg
      721 tattcaggaa gagcaattaa aaaagcagcc tctttttggc tcctatctcc tgctttataa
      781 gcactcatca agctgctctt agcacttttg aacaattaaa aaaccaagag cctcgagcac
      841 tcctgatttg tttaattgat gtattctgca attatgctga caatactttg cgtcctttgc
      901 gacgacggct agcaagcaca cgacggccgt ttttagttga catacggtga cggaagccat
      961 gcttgcgctg acgacggatc ttacttggtt gataagtacg tttcacagtg aatacctcct
     1021 catagatttt cgtattcgtt tagccggcta tttgtgatat cagttactaa acatacccta
     1081 ttattctata ataatcaaac tcccctgtca agctctattt tccttt
//
LOCUS       DARYXS010000189         1110 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.190, whole genome shotgun sequence.
ACCESSION   DARYXS010000189 DARYXS010000000
VERSION     DARYXS010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1110
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.190"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(345..575)
                     /locus_tag="TV193_001972"
     CDS             complement(345..575)
                     /locus_tag="TV193_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514115.1"
                     /translation="MKNIDEKILMTDGEIKQLQNKRKKPIIQSKQEERKKRDRRLYEK
                     GAVNQKILKIIEKREQTEENIEVQEEATDTEE"
     gene            complement(669..1082)
                     /locus_tag="TV193_001973"
     CDS             complement(669..1082)
                     /locus_tag="TV193_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514116.1"
                     /translation="MARKLAIIVIATGILFALIACILFFKKDILQVFPRMDIAWVGFL
                     VVAILLCVSGIWVFSISGKKQDWINETDERESLITAKANMVGYVIQTTLLGIVFFLLV
                     FMGYLNKVSGFSIIGVVLISGIVSWIYHLYLRKVE"
BASE COUNT          298 a          225 c          134 g          453 t
ORIGIN      
        1 tataggtcta cctcttgctt ctttgtctgt gttaatcgct tttcttgttt ttataactgc
       61 tctatacaag tcttaacttt ttctgcctgt ttaatttttt ctcgtatctc taatatttta
      121 ttgtgtaagc tctttttttc tttcttcata ttggcgactt ccgattttca tttgctaatg
      181 actaaggtct tgctttcgcc caaatgctct tttagatatt tcttggcact ctcaaataaa
      241 ataatctctg ctgtatcaac gttagctgat atgccctctg caagagcctt cggagaacgc
      301 acgcacctgt tgaggtgtat atgtacactc ttgtaaacaa gggactattc ctctgtgtcc
      361 gttgcttcct cttgcacttc tatgttttct tctgtttgtt ctcttttctc tatgattttt
      421 aggatttttt gattgactgc tcccttttca taaaggcgtc tatctctctt ttttctctct
      481 tcctgtttcg actgaatgat gggctttttt cttttgtttt gtaactgctt gatttctcca
      541 tctgtcatta aaattttttc atctatgttt ttcattttct attttcctct ctttctgttt
      601 tgagcaacaa aaaaacagta aaccattttt ttgatttact gttttctaat aaatattatc
      661 ttagttatct attctacttt tcgtaaatat aaatgataaa tccatgatac gataccactt
      721 atcaaaacaa ctccaattat agaaaaccca gaaactttgt ttaaatagcc cataaaaact
      781 agaagaaaaa aaactattcc cagtaaagtt gtttgaatca catatcctac catattagcc
      841 ttagctgtta ttaaggactc tctttcatcg gtttcattta tccaatcttg ttttttacct
      901 gaaattgaaa atacccatat tccactaaca cacagaagaa tagcaacaac gagaaagcct
      961 acccatgcaa tatccattct tggaaatacc tgtaaaatat cttttttaaa aaataatatg
     1021 caagcaatca aggcaaaaag tattccagta gcaataacta taatagctaa ctttcttgcc
     1081 ataaccatct ctttttttat atttcttttc
//
LOCUS       DARYXS010000190         1108 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.191, whole genome shotgun sequence.
ACCESSION   DARYXS010000190 DARYXS010000000
VERSION     DARYXS010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1108
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.191"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..1064)
                     /gene="xerS"
                     /locus_tag="TV193_001974"
     CDS             complement(<1..1064)
                     /gene="xerS"
                     /locus_tag="TV193_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEL1514117.1"
                     /translation="MKRDLLLTKIEEYKNIMPWYVLDYYQSKLSVPYSFTTLYEYLKE
                     YKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNIYSTKKGVS
                     QTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQK
                     LFLGDETMAFLDYVDKEYEYKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLD
                     LKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAY
                     RGLPNRIDASSIEKMVGKYSEGFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALD"
BASE COUNT          319 a          219 c          214 g          356 t
ORIGIN      
        1 ttatctaggg catttttttg ctcatcgtta acaatatgag tatagaggtc tgtaacttgg
       61 gtcgaggcat gaccaagctg atgacttact aggacctgtg actttgtagt atcataaagt
      121 ctcgttgcaa gcgtatggcg tagcttatga ggagttacac gaattttaaa gccttcagaa
      181 tatttaccta ccattttttc aatgcttgag gcatctatcc gattggggag cccacgatag
      241 gctgttaaaa agaaggctac atcctgtttt tctgcttgat agcggtcttt tcgaactgat
      301 aaataggctt ctaaatgagg cttggcaaaa gcagcaacat tgaccgaatc tctcttacct
      361 cccttacggg taacctcaac cagcatcatg ttgaggttga catccttaag gtctaggtta
      421 actgcctcgg ataaccgaat accagatgcc agcagtaggg cgataatggc taggtcgcgt
      481 tctttatttt ttcggaaaga agcctttgcc cgatttgaca gcttatattc atattcttta
      541 tccacatagt ctaaaaatgc catcgtctca tcgcctaaaa aaagcttttg tttaatattt
      601 tcagccctgg ctgctaaggt ttctcttttc tttttggttg ccaccttttt catgacattt
      661 cgataaaaat aaggctctcc atgctcattt tcaacctcct cagtaaggta tttatacaag
      721 ctggatagtg cagaaagggt acgattaatg gtggtttgcg ataccccctt tttagttgaa
      781 tagatgttca aggaaggacg ctcacgaaga tagagaataa aggcttccat atccttttta
      841 ctcaaatgct ccagagtagt caagtccaca tcagcaatcc tagcagcttt tgatagatca
      901 gaatcaatta accactcaaa aaagcgtttg tattctttca ggtattcgta caaggtcgta
      961 aagctataag gaacagatag cttagattga taataatcaa ggacatacca aggcatgatg
     1021 tttttgtatt cttcaatttt agtaagtagt aaatcacgtt tcataataaa ttctcacaat
     1081 gtttcgtcaa caaatgaatt atccattg
//
LOCUS       DARYXS010000191         1097 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.192, whole genome shotgun sequence.
ACCESSION   DARYXS010000191 DARYXS010000000
VERSION     DARYXS010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1097
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.192"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..1021)
                     /locus_tag="TV193_001975"
     CDS             complement(<1..1021)
                     /locus_tag="TV193_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1514118.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVIGETDYKKACHAIKAAGYATASDYAELLIQLIEQNDLQKWDAEALAKRKESQMISS
                     QCREVIEFYINLANAGMGVDKDGAYGTQCADVPCYAAKHWFGVDLWGNAADLLDSASA
                     QGWEVHRMPTDANPRAGAFFVMDAWFGGINYGHTGLVYVDSDGYTMQTIEQNIDGNAD
                     ALYVGGPARFNTRDFTNVAGWFYPPYQGDVAAQTVSTDPQTSDTIVETSKSGTFTLDA
                     AEINVR"
BASE COUNT          292 a          282 c          227 g          296 t
ORIGIN      
        1 ggcggacgtt gatctctgcg gcgtcaagtg taaaagtacc tgattttgat gtctctacga
       61 tcgtgtctga ggtttgcggg tctgtgctga ccgtttgtgc agcaacatct ccctgataag
      121 gaggataaaa ccagccggcc acattagtaa agtcacgagt attaaaacgg gccggacccc
      181 ctacatacaa cgcatctgca ttaccatcaa tattttgctc gatagtctgc atagtgtaac
      241 catctgagtc aacgtacaca agacccgtat gaccataatt gataccacca aaccaagcgt
      301 ccatgacaaa aaatgcccca gctcgtggat ttgcatctgt aggcatgcga tggacttccc
      361 agccctgcgc acttgcgcta tctagtaagt ccgctgcgtt gccccagaga tcgacaccaa
      421 accagtgctt agctgcgtaa caagggacat ctgcacattg cgtgccataa gccccgtcct
      481 tatcaacacc cataccagca ttagccaaat tgatgtaaaa ctcgataacc tctcgacact
      541 gcgaactaat catttgtgac tcctttcttt ttgctagggc ttccgcgtcc catttttgta
      601 ggtcgttttg ctctattagt tggataagca gctctgcata atcacttgca gtggcataac
      661 cagctgcttt tattgcatga caagcctttt tatagtcggt ctccccgata actgatttgt
      721 atcgtggatt atccactaaa aactggccat gatcaaggat tgactcgtcc caactgtcat
      781 aggctctaaa gcggtccacg agatccgtca cgacacctgg ctgatactcc tcttgtgtct
      841 tggtatcaaa agatttacca gaccatgagc tatctgcctt gataccaaac aatgcgttat
      901 gtggggcata cttgccccaa ccgctctcta aaatagcttg agcagccgtc agagatggca
      961 aaatcttatg attgtgccac tctgcgataa ctgcgctttt tatgtcgtct aaaaaggtca
     1021 tctgtcctcc tcacctaaaa acggataaaa gataagagca atcacagata gcggtaaata
     1081 tagtattgcg attgcta
//
LOCUS       DARYXS010000192         1077 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.193, whole genome shotgun sequence.
ACCESSION   DARYXS010000192 DARYXS010000000
VERSION     DARYXS010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1077
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.193"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            41..>1077
                     /locus_tag="TV193_001976"
     CDS             41..>1077
                     /locus_tag="TV193_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634-like element ISSeq4 family transposase"
                     /protein_id="HEL1514119.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVKQRILKKFGLLDELEL
                     EEPGILERLKREAKEDTLNNPKVLQVSYDLLAPMNQPDQSYGWMVLDNLFESLGLTAF
                     LKGIKTKSEYDLVQVLKLLVFQRILRPDSKLATYASQADLFGHWDISLNAIYRSLNKL
                     NTLKDDLQHHLHKVVSQMIKREASLVFYDVTNYYFETDIPDNELVSENGEILQEGLRR
                     RGPSKEHRPKPIVQLGLFRDTNGIPISYKLFRGNQTDPVTYLPAVEEVKKQFGIERLI
                     VVADKAMNSMANVSEMLKQEDGWLFSQKHRGRRGAPKDIQEHILDSSDWQFNPELTFA
                     KKSYIRERKLG"
BASE COUNT          337 a          209 c          228 g          303 t
ORIGIN      
        1 tttttcttgt tgtgtatggt tatatatgtt ataataaact atggctttta ttaaaacaac
       61 aacgaataaa gaaggtagga cgcatgtcta ccttgtagaa gggtatcgta aagatggtaa
      121 ggtcaaacag cgtatcctta aaaaatttgg tctcttagat gagcttgaat tggaagaacc
      181 agggattctt gagcgtctta agcgcgaagc taaagaagat actttaaata accctaaggt
      241 actccaggtt tcctatgacc tccttgcccc catgaaccaa ccggatcaat cttatggttg
      301 gatggttttg gataatctct tcgaatctct ggggctcaca gcctttttaa agggtatcaa
      361 aacgaagtct gagtatgact tagtgcaagt gctaaagcta ttagtttttc agagaattct
      421 ccgaccagat agtaaacttg ccacctatgc ctctcaagca gacttatttg gccattggga
      481 catcagctta aatgccattt atcgctcctt gaacaaattg aacaccttga aagatgatct
      541 tcaacatcat cttcacaagg tagtgagtca gatgatcaaa cgtgaagcca gtctcgtttt
      601 ctacgatgtc accaattatt attttgagac agatattcca gataacgagt tggtttcaga
      661 aaatggagag atactacaag aagggcttcg aagacgtggt ccgagtaagg aacaccgtcc
      721 aaaacccatt gtgcaattag gactctttag ggataccaac ggtattccga ttagctataa
      781 actgtttcga ggtaatcaaa ccgatcctgt tacctatctt ccagcggttg aggaagtcaa
      841 aaaacaattt ggaattgagc ggttaattgt agtcgccgat aaggcgatga atagtatggc
      901 taatgtttca gaaatgctca agcaagaaga tggctggctc ttctcacaga aacatcgcgg
      961 acgccgagga gctccaaaag atattcaaga acacatcctt gattcatcgg attggcaatt
     1021 taacccagaa cttaccttcg ctaagaaatc ttatatccgt gaacggaagt tagggaa
//
LOCUS       DARYXS010000193         1047 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.194, whole genome shotgun sequence.
ACCESSION   DARYXS010000193 DARYXS010000000
VERSION     DARYXS010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1047
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.194"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..239)
                     /locus_tag="TV193_001977"
     CDS             complement(<1..239)
                     /locus_tag="TV193_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin M precursor"
                     /protein_id="HEL1514120.1"
                     /translation="MRIFLRQNCRLVNMSTTFFIVVLSLVVFSVRMVSAEGTINIKDI
                     YSPRWDVDKTLSPTTLREIYNRDTIKKENKPVTGK"
     gene            complement(506..>1047)
                     /gene="spek"
                     /locus_tag="TV193_001978"
     CDS             complement(506..>1047)
                     /gene="spek"
                     /locus_tag="TV193_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeK"
                     /protein_id="HEL1514121.1"
                     /translation="IFNTDENTTVWNDNTFKKVISSNLSPSQERMFNVGDHVNIFAIV
                     KSYHVVCKEQFNYIDGGIIKTSDVKPEEKAIYINIFGEKELRTLTAKDKITFKNNIVT
                     LQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFWDIHYKDGGIRHTNLFTYPDYTDNETI
                     DMSKVSHFDVYLNEEFSKN"
BASE COUNT          359 a          187 c          121 g          380 t
ORIGIN      
        1 ctttttccag taacgggttt attctctttt tttatagtat ctctattata aatttctctt
       61 aaggtagtag gggataatgt tttatctaca tcccaccttg gagagtatat atccttaata
      121 ttaatagtcc cctccgcaga aaccatccta acagaaaata ccaccaatga caatactact
      181 ataaaaaaag tagttgacat attaaccaaa cgacaattct gacgtaaaaa aattctcatt
      241 tatcttatta ttctccttaa taaatcaata tagctgtgaa actatgtttt ttgaacttga
      301 acctcaaaat gcttaaatcg gaagtacttg agcagacttc ttaaaagata ataaactgat
      361 tctataacgc acagaaatta atctgagcgg ttttatcata ttcctcggtt gaccgatagt
      421 gatgcctaga agtctactaa aaccgtctaa ttcatcaaaa tctatttaaa tagactaaaa
      481 attaaattaa aatagcattc gaccgttaat ttttagaaaa ttcttcgttt aagtaaacat
      541 caaagtgact aactttactc atatcaatcg tttcattatc tgtatagtcg gggtaagtaa
      601 ataaattggt gtgtctaatg ccaccgtctt tataatgaat atcccaaaac ccttttttat
      661 acaaagaatc gtactcatac aattttattt tgctgtctcc catcaaactt ttcctaagtc
      721 taacatcaat ctcctgaaga gttacaatat tatttttaaa ggtaatctta tctttagctg
      781 ttaatgttcg taattctttt tcaccaaaaa tattaatata aattgctttt tcttctggtt
      841 ttacatcact tgtttttatt attcccccat caatataatt gaattgttcc ttgcatacaa
      901 catgatatga ctttactata gcaaaaatat tcacatgatc accaacatta aacattcttt
      961 cctgtgaagg agaaagatta ctagatatga ctttcttaaa agtgttatca ttccaaactg
     1021 tagtattttc atccgtatta aaaatca
//
LOCUS       DARYXS010000194         1045 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.195, whole genome shotgun sequence.
ACCESSION   DARYXS010000194 DARYXS010000000
VERSION     DARYXS010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.195"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..>1045
                     /locus_tag="TV193_001979"
     CDS             <1..>1045
                     /locus_tag="TV193_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1514122.1"
                     /translation="EKAKVLEIRDKKEVLSTLIFKDVKEVGEYQFHPQSEEFILNELS
                     ISEEKLKAPEHITDKIDKKEGYEAELVLDMKNKELRQHLRYNGYMLSSNVAVSYDSYK
                     AILKNLSYLLDDNHRNIMLTGYVNEQIEKDKAKEERKEPVYQEGMNVRYQGKEYIISE
                     IQDYKTYKTIKLDDSEGYLNGFITGSEIIPFRNERELDLEIISTTEKLQEQSINGEDL
                     ILLDIEEYNKKGLSVIFQNKEYEITGNNFNPVGMSRLQLVSNTEKLMTEISYTPQRPV
                     ANLYAKKDLLERFNLNEKNSEKSIEAKQMSLTDIFEEQDTTKGKEEISSEKERVPVNI
                     GAKVIYQGEEYTV"
BASE COUNT          448 a          122 c          203 g          272 t
ORIGIN      
        1 aagaaaaagc aaaggtgctt gaaattagag ataagaaaga agtcttatca actcttattt
       61 ttaaagatgt aaaggaggtc ggcgaatatc agtttcatcc acaaagcgaa gaatttatct
      121 taaatgaatt gagtatatct gaagaaaaat taaaagcacc ggaacatata acagataaga
      181 ttgataagaa agaaggctat gaggctgaac ttgttttgga tatgaaaaac aaggagttaa
      241 ggcagcattt aagatataac ggatatatgt taagtagcaa tgtggcggtt tcctatgata
      301 gttataaagc aatacttaaa aatctttctt atctgcttga tgataatcat agaaatatta
      361 tgcttaccgg ctatgtcaac gaacagattg aaaaggataa agcaaaggaa gaaagaaaag
      421 aacctgtata tcaagaggga atgaatgtaa ggtatcaagg caaagaatat atcatttcag
      481 aaattcaaga ctataaaaca tataaaacaa taaagctaga tgattcagaa ggatatttaa
      541 acggctttat aacgggcagt gaaattattc cttttagaaa tgaaagagaa cttgatttgg
      601 aaatcatatc tacaacagag aagttacaag aacaaagtat aaatggtgaa gatcttattc
      661 tgttagatat tgaagaatat aacaaaaaag gactttccgt tatctttcaa aataaagagt
      721 atgaaattac aggaaataat tttaatcctg taggaatgag caggttacaa cttgtctcga
      781 atacagaaaa actgatgaca gaaatttcat atacacctca aagaccggtc gcaaatcttt
      841 atgcaaaaaa agatctcctt gaaaggttta atttaaatga gaaaaatagt gaaaaaagta
      901 ttgaagcaaa gcaaatgtct ttaacagata tatttgagga acaggataca acaaagggaa
      961 aagaagaaat ttcaagtgag aaagaacgtg tacctgtcaa tataggggca aaggtaatct
     1021 atcagggaga agaatataca gtaag
//
LOCUS       DARYXS010000195         1040 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.196, whole genome shotgun sequence.
ACCESSION   DARYXS010000195 DARYXS010000000
VERSION     DARYXS010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1040
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.196"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            145..1040
                     /locus_tag="TV193_001980"
                     /pseudo
     CDS             145..1040
                     /locus_tag="TV193_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSeq3 family transposase"
BASE COUNT          355 a          190 c          221 g          274 t
ORIGIN      
        1 gacataaaat ctaacaattg gggggctatt tttatgacat tgagttatga agacaaggtt
       61 caaatctatg agctacggca cattggaaag tccattaaat gcttatcaga aaagtttagt
      121 attgcagaat ctgacctcaa atacatgatt cgcctgattg acaggtatgg gttagccatt
      181 gtccaaaaag gtaagaatag ttattattct ccagaactga agcaagagat aatagataaa
      241 gttctgattg atggtcaatc tcaaaaacag acgtccttag actatgcttt accaaattct
      301 agtatgcttt caaggtggat agcgcaatac aagaaaaacg gctatactat tcttgagaaa
      361 agaagaggga ggccaccaaa gatgggacgt caaccaaaga agactttaga acaaatgaca
      421 gagttggagc gactccaaaa agaattagac taccttagag cggagaatgc tgtgctaaaa
      481 aagctgagag aataccggtt gagggacgaa gcaaagctca aagagcaaca gaaatcatcc
      541 aagaattaat cggtcaattt tctctagcaa ctttgcttga aatccttgat ttatcgcggt
      601 caacctatta ttatcaagtc aagcaactag ctcaagaaga taaggacatg gacttaaagg
      661 agctcattca aggcatctat gatgaacatc atggcaatta tggctatcgt cgcattcatc
      721 tggaactaag aaatcgtggt tttatcgtca atcacaaaaa agtacaacgt ttgatgactg
      781 tcatgggctt aaaagctcgt atccgtcgta agcgcaagta ttcttcttac aaaggtgagg
      841 ttggcaaaaa ggctgataat ctgattaaac gtcagtttga aggttctaag ccctacgaga
      901 agtgctatac cgatgtgacg gaatttacct tacctgaggg gaaactctat ctatcgcctg
      961 ttcttgacgg ctataacagt gagattattg atttcaccct gtctcgatcg cctgacttga
     1021 agcaagtaca aaccatgctt
//
LOCUS       DARYXS010000196          985 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.197, whole genome shotgun sequence.
ACCESSION   DARYXS010000196 DARYXS010000000
VERSION     DARYXS010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..985
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.197"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(45..755)
                     /locus_tag="TV193_001981"
     CDS             complement(45..755)
                     /locus_tag="TV193_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1514123.1"
                     /translation="MAKKKGKLTLISLFVLVACLGVYSSIRQSENTSDVSAETVSTSS
                     TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQAPYYNFFGIKGAYNG
                     SSVTMTTWEDDGAGNTYYIDQTFRAYPTVADSLYDYTNLLSSDIYAGARKSNTLSYQD
                     ATAALTGLYATDTSYNWKLNNIIETYGLTAYDIVNNQAQEALAAAPLTSVWNPYRKSY
                     TDTETLAIDKAWAQRMGY"
BASE COUNT          293 a          202 c          172 g          318 t
ORIGIN      
        1 ggctagaact caagccttgg agtgctaagt catttttcta ttctttagta gcccattcgt
       61 tgtgcccatg ccttatcaat agcaagggtt tcagtgtctg tatagctctt gcgataagga
      121 ttccagacag aggtcaaagg agccgcagca agcgcttctt gcgcctgatt atttactata
      181 tcataggccg ttagaccgta ggtctcaatg atgttgttta atttccagtt atagctagta
      241 tctgtagcat acaagcctgt taaagctgct gtagcgtcct gataagacaa ggtatttgac
      301 tttctagcac ctgcataaat atctgagcta agcaaattag tgtaatcata taaggaatca
      361 gccactgtcg gataagctct aaaggtttga tcgatgtagt aagtatttcc agccccatcg
      421 tcttcccatg ttgtcatcgt cactgatgac ccattataag cccctttaat gccaaaaaaa
      481 ttataataag gtgcttgact taaagctgat ttaccgttag ctgactctaa aatagcttga
      541 gcaatcataa ccgaagcata caagtctctt tcttgagcaa caacactagc agttgctcca
      601 atctcttcaa taaaggcttg cgttgacgac gttgacacag tctctgctga gacatctgat
      661 gtattttctg actgtctaat tgaactataa acacctaagc aggctactag aacaaaaaga
      721 ctgataagtg tgagcttacc tttctttttt gccatttatc attccctctt tttttgataa
      781 atagattata gcacagaatg ctcataaaaa gacttatcca caaacaattt aatcatattg
      841 ataacttttg tctttaaatc gaaatatttt aatgtaaaga aggcttacca agtccataaa
      901 gcgaaggctt ttcataatct tttacgcctt atttgctata tcgccttgta atagcttcaa
      961 tacctttgaa aggttattac accta
//
LOCUS       DARYXS010000197          980 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.198, whole genome shotgun sequence.
ACCESSION   DARYXS010000197 DARYXS010000000
VERSION     DARYXS010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..980
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.198"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(171..461)
                     /locus_tag="TV193_001982"
     CDS             complement(171..461)
                     /locus_tag="TV193_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514124.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            complement(442..834)
                     /locus_tag="TV193_001983"
     CDS             complement(442..834)
                     /locus_tag="TV193_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514125.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKGYQKREDSLSERRH
                     VLDDLINSEYQKMSVFLKRLDLSANAASDFFKELDRLKDQSNAEFHLQRAALEEERAQ
                     STKTFRQEQDQRETELLDMRRAYANTNN"
     gene            complement(816..>980)
                     /locus_tag="TV193_001984"
     CDS             complement(816..>980)
                     /locus_tag="TV193_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514126.1"
                     /translation="VRDFQDYTQSKVSKLSALATDFENLNRDIQTVIDSKLETDQQLA
                     GEFRAWQTEL"
BASE COUNT          215 a          247 c          188 g          330 t
ORIGIN      
        1 tcagtacact ggtcctctct cgtctttagc tatcggtcac tctgtataca attatcccct
       61 tttaaaaata acaggacaaa agctctggag gctgatcgcc ttttttgatc atacttgctt
      121 ggtaggtatt gattgaaccc ctacggtctc ttataaatga caccatttga ctatagcttg
      181 ttgtattttg gcagcttctt ctttacgacc tgctccagct gatctctgac cgctcctttt
      241 atggccgtat ctagctgccc ttccatgatc tgaaggcttt ccttagtttg gctggcagtc
      301 gctttgatct ggtctttaaa cgtttttttg atcgcttcac cttggctgtt cgcaagccta
      361 gccactgtgg caatcctttg acgctccagc atttgacgca ttagcctcag ggcataggcg
      421 tattcttctt cgatataata ctcagttatt ggtattagca taagctctcc tcatatctaa
      481 taactctgtc tctctttgat cctgctcttg acgaaaagtc ttggttgact gtgctcgctc
      541 ctcttcaaga gctgcccgct ggaggtgaaa ctctgcgttg gattgatcct ttaagcgatc
      601 tagttccttg aaaaaatctg acgcagcatt ggcagatagg tctaaacgct tcaaaaaaac
      661 actcatcttc tggtactcag agttgatcaa atcatctaag acatgtcttc tttcggataa
      721 gctgtcttca cgcttctgat agcctttttt ctggcgcaga aagtcctgct cggcatcatc
      781 catctcccgc agcttacgat agatagccac ttcctctaca attctgtctg ccatgctcta
      841 aactctcctg ctaactgttg atccgtttca agcttgctat caataactgt ctgaatatct
      901 ctattcaggt tttcaaagtc tgtggccaag gctgacagct tgctgacctt ggattgagta
      961 tagtcctgaa agtctcggac
//
LOCUS       DARYXS010000198          964 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.199, whole genome shotgun sequence.
ACCESSION   DARYXS010000198 DARYXS010000000
VERSION     DARYXS010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..964
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.199"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            177..590
                     /locus_tag="TV193_001985"
     CDS             177..590
                     /locus_tag="TV193_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514127.1"
                     /translation="MTVKKKVIILLGMVAILVMGGIFMFSYNQNQAKMLERQFNHEQK
                     RIVLYLLNHYSGINEIEFNDIENNSTTGSKNVLLTINNKIKMEVTFFNLNDDTDNYVI
                     SWNGKLSLIDKNPITHLSSIDKIKVKYWSNNDSNR"
     gene            574..828
                     /locus_tag="TV193_001986"
     CDS             574..828
                     /locus_tag="TV193_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514128.1"
                     /translation="MIVTDKNYNDIADGVYKVDAGKVIRPWRNGKTFKTNGKDYRVLK
                     TEDNPDNGMQAIAVAPIKGSEVGKSHIMIVYVKSSYWLAS"
BASE COUNT          381 a          113 c          192 g          278 t
ORIGIN      
        1 agtatatgat gttgatgcta ataaagtaac tattcctgtt agaaaaaata cggatattct
       61 taatcgttat gtcaaagtcc ttgaagccga agacaatcct gacaacggta tgcagtttac
      121 ggtgtcaaag agtaatagga atgttctagc tttaaattat aaactaagga gcttctatga
      181 cagtaaaaaa gaaagtcatc attttattag gaatggtagc aattttagta atgggaggta
      241 tatttatgtt tagctataat cagaatcaag cgaaaatgtt agaacgacaa tttaaccatg
      301 aacaaaaacg aattgtcttg tatttgttaa atcattatag cggaattaat gagatagaat
      361 ttaatgatat tgaaaacaac agtacaacag gttctaagaa tgtattgctg acaataaata
      421 ataaaattaa aatggaagtt acatttttta atttaaatga tgatacagat aactatgtta
      481 ttagttggaa tgggaaatta agtttgatag acaaaaatcc tataactcat ttaagttcaa
      541 tagataaaat aaaagtaaaa tattggagta acaatgatag taacagataa aaattataat
      601 gatatagccg atggggttta taaggttgat gctggcaaag ttattagacc ttggcgaaac
      661 ggtaagactt ttaaaactaa cgggaaagat taccgcgtcc tcaaaacaga agacaacccc
      721 gacaatggta tgcaggctat tgctgtagct ccgattaagg gtagtgaggt gggtaagagt
      781 catatcatga ttgtttatgt aaaaagcagc tattggctag cgtcctagca ataaaaggag
      841 ttgatgatga aaaagcaaca aagcaaacga cggaaactaa ttggcatagt ggctttaata
      901 acaattttag gaggaatact aacaatgaat tggtttaatg acgaaaaact aaatagagag
      961 cgta
//
LOCUS       DARYXS010000199          953 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.200, whole genome shotgun sequence.
ACCESSION   DARYXS010000199 DARYXS010000000
VERSION     DARYXS010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..953
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.200"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(108..>953)
                     /locus_tag="TV193_001987"
     CDS             complement(108..>953)
                     /locus_tag="TV193_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1514129.1"
                     /translation="SATHVLEILDKTLDNLDKIKNADFLDDNGKDMELSSHNIVFDKV
                     RFAYDKIPIIKDVSFEIKENTVTAIIGPSGSGKTTICNLISRFYDVSGGSIKIGNVNI
                     KNLTLSSLLSNISTVFQKVYLFNDTIENNIKFGNPNVSKEEIINAAKKSHCHEFIMNL
                     PNGYETIVGEGGDFLSGGEKQRISIARAMLKDAPIIILDEATSSIDPENEYLIQRAIS
                     NLSKGKTVIIIAHRIVTIEEADQIIVLKEGEIAQIGKHTELMSQDGLYRDYMRIRGKT
                     EDWKI"
BASE COUNT          296 a          194 c           87 g          376 t
ORIGIN      
        1 aaatataatt atcttcccat ttagacactt tttccataaa aagcgaacct atattaccat
       61 tgcaacctaa aactcctata ttatacataa acctcctcct atctatatta tattttccag
      121 tcctctgttt tacccctgat tctcatataa tctctataca gaccatcttg gctcatcagt
      181 tctgtatgct ttcctatttg agcaatctct ccttctttca aaacaattat ctgatctgct
      241 tcttcaattg ttacaattct atgagcaata ataattacag tcttaccttt actcaaattc
      301 gatattgctc tttgaattaa atattcgttt tcaggatcta tgcttgatgt tgcttcatcc
      361 aaaataataa ttggagcatc ttttagcatt gcccttgcta tagatattct ttgtttttct
      421 ccaccagata aaaaatcacc accttcacca acaatagttt catatccatt tggcaaattc
      481 attataaatt catgacaatg tgacttcttc gctgcattta ttatttcttc cttacttaca
      541 ttcggattac caaattttat attgttttcg attgtatcat taaacaaata caccttttga
      601 aatactgtac ttatatttga aagtaaactt gataaagtca aattttttat atttacattt
      661 ccaattttta tactcccacc acttacatca taaaaacgag aaatgagatt acaaattgtt
      721 gttttacctg accctgatgg tcctataata gctgttaccg tattttcctt tatctcaaat
      781 gaaacatcct ttataattgg gattttatca tatgcaaatc ttactttgtc aaaaacaata
      841 ttatgactac tcaattccat gtcttttcca ttgtcatcca aaaaatcagc attttttatc
      901 ttatctaaat tatctaatgt tttatctaaa atttccaaaa catgagttgc aga
//
LOCUS       DARYXS010000200          949 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.201, whole genome shotgun sequence.
ACCESSION   DARYXS010000200 DARYXS010000000
VERSION     DARYXS010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..949
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.201"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..390)
                     /locus_tag="TV193_001988"
     CDS             complement(<1..390)
                     /locus_tag="TV193_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1514130.1"
                     /translation="MAFFNYSQALTVGQIDIKNARLKAGKTQKELAKLIGVTKQTIIN
                     DEKGTTEPSWDRLQEIATALNVDIDTLFPYNMLGEKRDFKWMEHLERLENNWLYSRMA
                     EEEVLLQKILDFAIFQNKLDKNTLTTKE"
     gene            complement(616..688)
                     /locus_tag="TV193_001989"
     tRNA            complement(616..688)
                     /locus_tag="TV193_001989"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(653..655),aa:Lys,seq:ctt)
     gene            complement(690..883)
                     /gene="ssrS"
                     /locus_tag="TV193_001990"
     ncRNA           complement(690..883)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="TV193_001990"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
BASE COUNT          283 a          181 c          158 g          327 t
ORIGIN      
        1 ttctttagtt gttagagtgt ttttatctaa tttattttga aatattgcaa aatctagaat
       61 tttttgaagt aatacttctt cctcggccat acggctataa agccaattat tttcgagtct
      121 ctctaggtgc tccatccact taaagtctct tttttctcct aacatattgt agggaaataa
      181 ggtatcaata tcaacattta aggctgtagc aatctcttga agcctatccc atgaaggttc
      241 agtagtcccc ttttcgtcat taataattgt ttgcttagta actcctatta atttagcgag
      301 ttctttttgt gtttttccag cttttaagcg agcattttta atatctattt gtccaactgt
      361 taaagcctgc gaataattaa aaaaagccat ttttctccaa attccgtcgc aggtgatgga
      421 ggtgaaaata ctccgattgt atcaccttgt gttaattata ttattgtcat gtgttagctc
      481 tctttttaaa aagtaataaa ttctttattt aacatcatat cataaaaaat tgtttcgggg
      541 acaaatggtg ggacaaaccc tctttaggca agcaaaaaag ccctgcaata aaggcttttt
      601 gtcgttttta cactataccc cctacagggc tcgaacctgt gacccataga ttaagagtct
      661 actgctctac caactgagct aaggaggtaa ggaaagctgt attggcaccg gtgattcacg
      721 ttttgtattg aacccgcacg atataagcag gtgggcaaca tacttctctt cagattgctt
      781 ccacgtgaaa cggcttgcat actagagata gactttgttt ccctaaaata caaaaaaata
      841 gtcggtcaac acttagatgt gaattcgtat gccacagcaa taactctatg ctcttatgat
      901 accacttttt gaaaattttt caagccctaa aatgaaaaaa agatcgtat
//
LOCUS       DARYXS010000201          945 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.202, whole genome shotgun sequence.
ACCESSION   DARYXS010000201 DARYXS010000000
VERSION     DARYXS010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.202"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..359)
                     /locus_tag="TV193_001991"
     CDS             complement(<1..359)
                     /locus_tag="TV193_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL1514131.1"
                     /translation="MDLSLQEYVKGHGYELLFYDNRGTDKEAFVNHDCKVLGIGSYLD
                     DHEKKKAIYHEIGHKEHTNRQYELNRELCELEADRNMIHHLLKEELSYLDNVNEFNYA
                     RFMEKYKLKTITDEKMV"
     gene            complement(362..712)
                     /locus_tag="TV193_001992"
     CDS             complement(362..712)
                     /locus_tag="TV193_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1514132.1"
                     /translation="MFPTFEKIKELCKQRGITLIQLEETLEYSRNTLYKLKTQKPNAE
                     RIAEIADYFNVSTDYLLGRTDNPAIANGTTSQKTIDFKEIAAQSMSYDGKPLTDDDID
                     LIAAVLEQRFKNRD"
BASE COUNT          283 a          155 c          152 g          355 t
ORIGIN      
        1 attaccattt tttcatcggt aattgttttt aacttatatt tttccatgaa acgagcatag
       61 ttgaattcat ttacattgtc taaataagat aactcttctt ttagcaagtg atgaatcata
      121 tttctgtctg cttctaattc acacagttct ctatttagtt catactgtct gttggtatgc
      181 tctttatgac cgatttcatg atatattgct ttcttttttt catgatcatc aagataagaa
      241 ccaataccaa gaactttgca gtcatggtta acaaacgctt ctttatctgt gccacggtta
      301 tcataaaata aaagctcata accgtgacct ttgacatact cttgaagtga taagtccata
      361 gttaatctct attcttgaat ctttgttcta agactgctgc aatgagatca atatcatcat
      421 cggtaagtgg ttttccatca taagacattg actgagcagc tatctcttta aagtctattg
      481 ttttttgact agtggtgcca ttagcaatag caggattatc agtgcgacca agcaaataat
      541 ctgttgaaac attgaagtag tctgctattt cagcaattct ttcagcgttg ggtttttgag
      601 ttttcaactt atagagtgta tttcggctat attctaaagt ttcctctagt tgaataagtg
      661 taattccacg ctgtttgcac aattctttga ttttttcaaa cgtcggaaac attgatttat
      721 caacctttct aaggcatgac aaaaaatatt tcaacttttt gggtgaaaaa tgttgacaat
      781 tcaaccaaat gggtgtatca tattttttgt aagcaagaga taactaaaaa aacaactaag
      841 caaacaacta taaaacagtt ttggcgaacg agtttaagtt gatttgttaa ggttctttaa
      901 tatgctttaa ttctaacttt ttaggtgtga gttgtcaagt ggtca
//
LOCUS       DARYXS010000202          944 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.203, whole genome shotgun sequence.
ACCESSION   DARYXS010000202 DARYXS010000000
VERSION     DARYXS010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..944
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.203"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            131..805
                     /locus_tag="TV193_001993"
     CDS             131..805
                     /locus_tag="TV193_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1514133.1"
                     /translation="MQNEKELQITLRNVSKKYGEHSILENISLDIYKGDFVCIFGKSG
                     GGKTTLLNIIGTLENYDSGSVTCFSNRDPIKAPKVGELLRREKIAYLFQNFALVEKMT
                     VEENMMLAAKYNQEKNKKNLIEAALNKMGISDKLKSKVYELSGGEQQRVALARNMIKP
                     FEIMLADEPTGSLDYENKKIVIDTLIRLNDEGKTIVVVSHDKDFEKVAHKNYIIEKSA
                     IREVLR"
     gene            802..>944
                     /locus_tag="TV193_001994"
     CDS             802..>944
                     /locus_tag="TV193_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1514134.1"
                     /translation="MKRKIALLVPVIVLCICGLFFYMNRNSDDIDVAFTVKNETKEKI
                     DTVG"
BASE COUNT          369 a           86 c          200 g          289 t
ORIGIN      
        1 gagtatgtct aaacttttga ttagtttaat aataggtatt tgtggaagct ttatatgttt
       61 tggcatagaa attttacaac taaagaaaag tgaaagaagc attgtactta ggttaaagga
      121 gggttgttaa atgcaaaatg aaaaggaatt gcaaataacc ttaagaaatg tctctaagaa
      181 atatggagaa cacagtattt tggaaaatat tagtttggat atttataaag gagattttgt
      241 ttgtatcttt gggaaaagtg gaggaggaaa aacaacactt ttaaatataa ttgggacatt
      301 agaaaattat gatagtggta gtgtaacctg tttttcaaat cgagatccta taaaagctcc
      361 taaagtagga gagctattac gcagagaaaa aattgcttat ttatttcaaa attttgcttt
      421 ggtggaaaaa atgacggttg aggaaaatat gatgcttgct gcaaaataca atcaagaaaa
      481 aaataagaaa aatcttatag aagctgcctt gaataaaatg ggcatttcag acaaattaaa
      541 atcgaaggtt tatgaacttt caggtggaga acagcaaagg gtagctcttg caagaaatat
      601 gataaaaccg tttgaaatta tgttggcgga tgaaccgaca ggttctcttg attatgagaa
      661 taaaaaaatt gtaatcgata cacttattag attaaatgat gaaggtaaga caatcgtagt
      721 tgtaagtcat gataaggatt ttgaaaaagt agcacataag aattatatta ttgaaaagtc
      781 agctataagg gaggtgttga gatgaaaagg aagattgctt tattagtacc ggttatagta
      841 ctgtgtattt gtggtttatt cttttacatg aacagaaata gtgatgatat tgatgttgca
      901 tttacagtaa aaaatgaaac aaaagaaaaa atagatacag tggg
//
LOCUS       DARYXS010000203          939 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.204, whole genome shotgun sequence.
ACCESSION   DARYXS010000203 DARYXS010000000
VERSION     DARYXS010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..939
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.204"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..>939)
                     /locus_tag="TV193_001995"
     CDS             complement(<1..>939)
                     /locus_tag="TV193_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL1514135.1"
                     /translation="SIFLLASNIIPAWYTSILFMTACMIGNIAEKQVILSGITSGAAW
                     LVISGVIIGAAVKHTELDRLLARFFIPVCMGKYSKVLFGTILLGVVLIFLMPSAMGRV
                     VLLLPILNALSLELGYEKGSKEWEGIVMSGVLATYIPAFYVLPSNVPNNVFTGAILSL
                     YSINISYSRYFLLYFPILGVGKILILYFTMRLFYRRCKDSICVSKKAIDITKEQKLLI
                     VLLFITLSFWMTEHIHKVPTGWTGMATALIVMLPNSNFMEKQPLRKINFEPFFYVAGI
                     ISLGNIAKSSGLANVIAVHLINIVSLETASAFNVLTF"
BASE COUNT          340 a          181 c          130 g          288 t
ORIGIN      
        1 aaaagttaaa acattaaatg cacttgctgt ttccaaagaa acaatattga ttaaatgcac
       61 agcaatgaca tttgcaagtc ctgaagattt tgctatattc cctaaactta tgattccagc
      121 tacataaaaa aatggctcaa aatttatttt tcttaaaggt tgcttttcca taaaatttga
      181 atttggtaac attacaatca aggcagttgc cattcctgtc caaccggttg gtactttatg
      241 aatatgttct gtcatccaga aagacagagt tataaataac aaaactatta acaatttctg
      301 ctcttttgtt atgtcaatgg cttttttgga cacgcaaatc gaatctttac atcttctata
      361 aaataaccgc attgtaaaat ataaaatcaa tatttttcca actcctaaaa tagggaagta
      421 caagagaaag tatctgctat aggatatatt tatggagtaa agacttaaaa ttgctccagt
      481 aaaaacatta tttggaacat tggaaggtaa tacataaaat gcaggtatat aggttgctaa
      541 aacccctgac ataacaattc cttcccattc cttacttcct ttttcataac ctaattctaa
      601 agatagggca tttagaatag gtaaaagcaa aactactcta cccattgctg atggcatcaa
      661 aaaaattagt accactccta gcaaaatcgt cccaaataac actttagaat atttccccat
      721 gcacaccgga ataaaaaatc tcgcaagtaa tctatcaagt tcagtatgct ttactgccgc
      781 ccctataata acacctgaaa taacaagcca tgctgcacct gaagttatcc ctgataagat
      841 gacttgcttc tcagctatat tccctatcat acaagctgtc ataaataaaa tgcttgtata
      901 ccatgcagga attatattgc ttgccaaaag gaagataga
//
LOCUS       DARYXS010000204          925 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.205, whole genome shotgun sequence.
ACCESSION   DARYXS010000204 DARYXS010000000
VERSION     DARYXS010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..925
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.205"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(427..783)
                     /locus_tag="TV193_001996"
     CDS             complement(427..783)
                     /locus_tag="TV193_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514136.1"
                     /translation="MEDTYMTQACKKFMVSTMAALALAGVCLTASTHISKADDYVYGD
                     VEYLLTPKQEGYDDLVSFLESLGLNHFDATLYSDSMADQDYKKLLADFKGKTRSEVIS
                     AVLSELAKFYNDYSPF"
BASE COUNT          281 a          149 c          188 g          307 t
ORIGIN      
        1 tttatttatt agtaaatagt gatgagatag tagagatgct ggcagactgg atctctataa
       61 tggatatttc agcttggttt atgttagcgt tacctatttt accaatgatg ataccgtttg
      121 gtattgttgg tgtcatgcct tagacatgag ctgttattat tgagaccact aataagagct
      181 agtgtaggct ttgatgttat tgggattctt gcacaatctt agccaagctt agtcagcaaa
      241 tcagggcatt agctaggata gtaaggacaa tggtgcagtt attacttgat tagctaggcg
      301 gacgatttag gagatggtct ggttactaag cagattgaca aagagaagca tagctctatc
      361 aagttaaaac cgctcggaag gttgtctgag cagttttgat ctatgataac ttattgggtt
      421 atttcattaa aaaggggaat agtcgttata aaatttagct aattcagata gaactgcaga
      481 aataacttca ctacgagttt tacccttaaa gtcagctagt agctttttgt aatcttgatc
      541 agccatagag tccgaataaa gagtggcatc aaaatggtta aggcctagac tctccaagaa
      601 tgacaccaaa tcatcgtatc cttcttgctt aggcgtcaaa agatattcca cgtcaccata
      661 aacatagtca tcagctttgc tgatgtgggt tgaagctgtt aggcagactc ctgccaaagc
      721 tagggcagcc attgtagaaa ccataaattt cttacaagct tgtgtcatat aagtgtcctc
      781 catttccaac ggttcctttg tccgtcgtta tttttgtgat attttcctta tcacaatgtt
      841 agtttaactc aaaatctgtc aaaagtcaaa tgtttttgta attaaattaa taaagtgttt
      901 ttaaaaaatt aaataaatgt agctt
//
LOCUS       DARYXS010000205          918 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.206, whole genome shotgun sequence.
ACCESSION   DARYXS010000205 DARYXS010000000
VERSION     DARYXS010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..918
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.206"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            57..476
                     /locus_tag="TV193_001997"
     CDS             57..476
                     /locus_tag="TV193_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514137.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGEELKKKKYR
                     QEQDRVVKYIGEHIELCNGQPITKIEFIEFQLETATTGTWSITTIVNEKYLIHFSEDR
                     LGEEIRTSYYSPKEFKQYSEKMRNNMTNVETIYYEEK"
     gene            473..>918
                     /locus_tag="TV193_001998"
     CDS             473..>918
                     /locus_tag="TV193_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514138.1"
                     /translation="MMIDRDYKNISEDVYKVDSGKERDPIQEGYPVANGKYRVLEAED
                     NPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITA"
BASE COUNT          338 a          152 c          191 g          237 t
ORIGIN      
        1 tttgtaaaag caaaaaactt gcaacacctt atgataaagc ataaaggaat acaagcatga
       61 tagtctacct aaagcaacac aaaaattact ggaaattagt cagcatagcc gctttaatca
      121 ttattttagg aggaatacta acaatgaatt ggcttaatgg cgaagagcta aaaaagaaaa
      181 agtacagaca agagcaggat agggtagtga aatacatagg agagcatata gagctatgta
      241 atggtcagcc tataacaaaa attgagttta tagaatttca gttagaaact gcaaccaccg
      301 gaacttggtc aataacaaca attgttaatg agaaatatct gattcatttt tcagaagata
      361 gattaggtga agaaatacgg acttcctatt attctccaaa agaatttaag caatacagtg
      421 aaaagatgag gaataatatg actaatgttg aaacaattta ttacgaggag aaatgatgat
      481 tgatagagat tataaaaata tttcagagga tgtgtataag gttgattctg gtaaagaaag
      541 agatccgatt caagaaggat atccggttgc caatggaaaa taccgcgttc ttgaagccga
      601 agataacccc gacaatggta tgcaggctat ggctgttgtg ccaataaaag atggcaaaga
      661 ggatagaagt catatcgtca ttgcctatgc cgggacaaat agcagtgata tacgcgatat
      721 tgacaccgat attcaatccg ttgtttttgg agatgatcaa tacctgtgta cccatgagga
      781 gcctgattct tttaaagtag tcaagagtca gctaagtact gctaaagcct tttccgacta
      841 cattaggaca agctacccta acgctgccat ctcctatacc ggacactctc tgggaggcta
      901 tctggcactc atcacagc
//
LOCUS       DARYXS010000206          902 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.207, whole genome shotgun sequence.
ACCESSION   DARYXS010000206 DARYXS010000000
VERSION     DARYXS010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..902
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.207"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(308..>902)
                     /locus_tag="TV193_001999"
     CDS             complement(308..>902)
                     /locus_tag="TV193_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1514139.1"
                     /translation="NLTYQVENRKIFTNFSFEFKKGNTYAIIGPSGVGKTTLAKLILN
                     YYPKHLYDGEIRIDGRNIAEINSESLYKKIAFVQKNDFLVEGNVSDNIKLDGSLNLTD
                     KLKDSLGFDETFLNKKLFRVQSLISEGEKQRIDLARFLNRRYSIYIFDEPTGNLDPAR
                     SKAILDYILSIKNAIIIVITHNQDIKTLEQFDEVICL"
BASE COUNT          300 a          163 c           92 g          347 t
ORIGIN      
        1 cacaacaaga aataaaatct gaccaaaaaa ttgagtttcc tttgatttct agaacatcat
       61 tatcatcagc tcctatcctt aatttatcat tttgccatga atatacaatc ctatcctgat
      121 tccattttgg aaaaaaatta ttcattttat tgtcctttct atattttaca aaggcatgca
      181 aattctcatt gcatgccttt gtgattaaac aaaataccaa tttgtggttt gttcatttcg
      241 aacttcgaca aactctagtt ctaaaacttc aaaatcttcc ataatcatgt tcatcacccc
      301 ctttcattta caaacaaatg acttcatcga attgttctaa cgtttttata tcttggttgt
      361 gagtaatcac aatgatgatt gcattcttta ttgataaaat ataatccaat atggctttag
      421 atctagctgg atcaagatta ccagttggtt catcaaaaat ataaatagaa tatctacggt
      481 ttaaaaatct tgctaaatca attctttgtt tttctccttc tgagattaaa gactgaactc
      541 taaataattt tttgtttaaa aatgtttcat caaatcctaa actatctttg agcttgtctg
      601 ttagattcaa actcccatct aatttaatat tgtctgaaac attaccttcc acaagaaaat
      661 catttttttg aacaaacgca atcttcttat acaaactttc tgagttaatt tcagcaatat
      721 ttcttccatc aattcttatt tccccatcat ataaatgctt tggataataa tttaatatca
      781 gttttgctaa tgttgttttc ccaacccccg aaggaccaat aatggcataa gtatttccct
      841 ttttaaattc aaatgaaaaa ttagtaaata tttttctatt ttcaacttga taagttaaat
      901 ta
//
LOCUS       DARYXS010000207          855 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.208, whole genome shotgun sequence.
ACCESSION   DARYXS010000207 DARYXS010000000
VERSION     DARYXS010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..855
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.208"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            441..>855
                     /locus_tag="TV193_002000"
     CDS             441..>855
                     /locus_tag="TV193_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622467.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1514140.1"
                     /translation="MVDNLGNPITEQVTLKAGQIIDRYGSSSGRFTSPIENGVTLPFN
                     KRGLPYPEGYQDYYKYELVMDLTKKNIVNAYYQSEEIIRKQISVEMKKWNLSFDDLAN
                     IQKGEITKVFGQGGGIQIKFPTGVGIYKKMGLLKEI"
BASE COUNT          289 a          138 c          202 g          226 t
ORIGIN      
        1 attaataaaa gaactattga aataccatat ggcattttga gttcagatgc ccagtcatgg
       61 caggaggcag cgaacaagat gctcagcgag ctacattagt aggcaatatc ctaggaggat
      121 tcgccgcctc aagcgtcgcc agacggttca gcttgaatga gccaatagca gctagggtga
      181 cgaaaccgac ctacagccgc cggcagcttt tgaagaacct tgagaacagc aggctggcaa
      241 gagaaagctc gaggtttgat gattatcttc gaagagaata ccggttaaag ggaaggtatt
      301 ttgcagaaag aaccactatt tcaaatggaa agataggtta tctttcatct gactattttg
      361 aaggcaagca aattccggtt cgctctagag cttttgttga cgaagcaggc catattaaat
      421 ggccaaatgc cgatggcttt atggtggata atttaggtaa tcctataacg gagcaggtca
      481 ctctcaaagc aggtcaaatc attgatcgat atggatcaag tagtggtcga tttaccagtc
      541 cgatagaaaa tggggtgaca ttaccattta ataaacgtgg attaccctac ccagaaggat
      601 atcaagacta ttataagtac gaattagtaa tggatttgac gaagaaaaat attgttaatg
      661 cgtattatca atctgaagag attataagaa aacaaatatc tgtagaaatg aaaaaatgga
      721 atctttcctt tgatgattta gctaatattc agaagggtga gattaccaaa gtatttgggc
      781 aaggtggagg aattcagatt aaatttccga caggtgttgg tatttacaag aaaatgggtt
      841 tattaaagga gatta
//
LOCUS       DARYXS010000208          837 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.209, whole genome shotgun sequence.
ACCESSION   DARYXS010000208 DARYXS010000000
VERSION     DARYXS010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..837
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.209"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            56..406
                     /locus_tag="TV193_002001"
     CDS             56..406
                     /locus_tag="TV193_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1514141.1"
                     /translation="MFSTFEKIKELCKSRGISIAKLEENLGLSKNAIYAIKRNQPSAE
                     RLQEIADYFHVSTDYLLGRTDNPKIAQSDHTPSAIDLKKDAEETFFFDGHELNDEDID
                     LITSILETRIKNRK"
     gene            420..824
                     /locus_tag="TV193_002002"
     CDS             420..824
                     /locus_tag="TV193_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL1514142.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDG
                     TYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLREELSYWDNVEEFNYVR
                     FMQQYDLTSFVDEVMVKEEYYNLTGYYDKKSF"
BASE COUNT          310 a          151 c          157 g          219 t
ORIGIN      
        1 aaatagatat ttctctaaaa tatttttcgt gatgcttaga aaggttgata tatcaatgtt
       61 ttcaacattc gaaaaaatca aagagctttg caaaagtaga ggaatctcta ttgcaaagct
      121 agaagaaaat cttggattaa gtaaaaacgc tatttacgca atcaagagaa accagccgtc
      181 cgctgaacgt cttcaagaaa tcgctgacta cttccacgtc tctacagatt accttttagg
      241 tcgcacagat aatcctaaaa ttgcacaaag tgaccatacc ccgtctgcaa tcgatctaaa
      301 aaaagatgca gaagaaactt tcttcttcga tgggcatgaa ctcaacgacg aggatataga
      361 ccttatcaca tctatattgg aaacgcgcat caaaaataga aaatagagag gacagctcta
      421 tgatgacacc agaaacagtc tgtcaggaaa agggaatcga tttagtgtac ttcgacggta
      481 gggggacaaa cacccctgga atgtttaaca aaaaacacaa cgtcattgcg attgacactt
      541 atcttgacgg cacatacaag cacaaagtca tctatcatga actaggacat agagaacata
      601 ctgcgagtta ttacaagcta aacaaagaaa aagcagagct acaagctgat agatgtatga
      661 tacatcactt gctgagggaa gaattgtctt attgggataa tgtagaggaa tttaactacg
      721 tccgatttat gcaacaatac gatctaactt catttgtcga tgaagtcatg gtcaaggaag
      781 agtattataa tttaacaggt tattatgaca aaaagagttt ttaattctag ctttcaa
//
LOCUS       DARYXS010000209          797 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.210, whole genome shotgun sequence.
ACCESSION   DARYXS010000209 DARYXS010000000
VERSION     DARYXS010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..797
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.210"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..709)
                     /locus_tag="TV193_002003"
     CDS             complement(<1..709)
                     /locus_tag="TV193_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEL1514143.1"
                     /translation="MGMWFEYVNKEMENTKASLFVFPFAGGGVSSFRRWGNQFKDINL
                     FVAQYPGRENRFSEKAISNIEELVKGLFEDLKMTFDFNSPYYFFGHSMGTKIAYELAL
                     KIKENGLPNPNGIIISAGRAPCYKEPNPIYHLDDEGFIEGLRRYDGTPNEILDNKDLI
                     GIFLPTLRADFIIDEDYQDTKGEKLNSKILGLMGDIDEEMELEELLKWQDYTTKEFSY
                     RYINGKHMFVNTSPESVI"
BASE COUNT          248 a          170 c           91 g          288 t
ORIGIN      
        1 ttatcacact ttcaggagat gtatttacaa acatatgctt gccattaata tatctgtaag
       61 agaattcttt cgtcgtataa tcttgccatt ttaaaagttc ttcaagttcc atttcttcat
      121 caatatcacc catcagacct aaaatcttgc tattcaattt ttcccctttt gtatcctggt
      181 agtcctcatc gataataaaa tcggctctta gtgttggtaa aaaaatccca atcaaatctt
      241 tattgtctaa tatctcattt ggagtaccat catatcttct taacccttca ataaatcctt
      301 catcatctaa atgataaatc ggattcggtt ccttatagca aggggctcgc ccagctgata
      361 tgataattcc attcggattt ggtaacccat tttctttaat tttcagagcc aattcataag
      421 caatcttagt tcccatacta tgcccgaaaa aataataagg tgagttaaaa tcaaaagtca
      481 tttttaagtc ttcaaacaat ccttttacaa gttcttctat gttgctaatt gctttttcag
      541 aaaacctgtt ttctctccct ggatactgtg caacgaagag atttatatct ttaaattgat
      601 taccccatct tctgaatgat gatactccac cacctgcaaa tggaaacaca aataaactag
      661 ctttcgtgtt ttccatttct ttattaacgt attcgaacca cattcccatc aaaacacctt
      721 ccatctgatt attaatatac tactagaact attattgtta gatacatcta acaataatag
      781 tttaatcctt ctaacat
//
LOCUS       DARYXS010000210          763 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.211, whole genome shotgun sequence.
ACCESSION   DARYXS010000210 DARYXS010000000
VERSION     DARYXS010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..763
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.211"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(241..>763)
                     /locus_tag="TV193_002004"
     CDS             complement(241..>763)
                     /locus_tag="TV193_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1514144.1"
                     /translation="INFAFMLAGMIPVMWIMMPSLIALFTGVPYMMICNKVQKAGAIL
                     IMGTVTVLIYYATGQFTTVILATFAVGCILAEIIRAITRYTSFIGNTLSFALFSIGMI
                     GSPLPIWLFKESFFAHISEVGMSQDYINALEKFTSPAILIGVIILTFICSLVGALIAK
                     RMMNKHFKKAGII"
BASE COUNT          293 a          143 c           95 g          232 t
ORIGIN      
        1 atagcaatta aacttggtag tttcggtaaa accaaaaatt ctatcaaata aagcaaccaa
       61 taagtaaaaa tgaatttgat tgctatccta caatatccat tacacattgc ataaacacag
      121 ttccaaatta atagcacaaa taatgcataa actgtggata cattaaatat cgtaaagttt
      181 aagataaaaa gcagggaaat ccctgctctc ggatctattt ttaatctata ttcacgcatt
      241 ttatataatt cccgcttttt taaaatgttt attcatcatt cttttcgcaa tcaaagcccc
      301 aactaacgaa caaataaaag tcaaaataat aactcctatc aaaatcgctg gcgaagtaaa
      361 cttttccaag gcatttatgt aatcctgcga cataccaacc tctgatatat gagcaaaaaa
      421 tgattcttta aacaaccaaa taggaagagg cgatcctatc attccaattg aaaatagtgc
      481 aaatgataaa gtattcccta taaaacttgt atatctagta attgctctaa taatttcagc
      541 taatatacaa cctactgcaa aagttgcaag aataactgtt gtaaattgtc ctgttgcata
      601 atatatcaaa actgtaactg ttcccatgat taaaatagca ccagcttttt gaactttgtt
      661 gcaaatcatc atgtatggca cccctgtaaa taaagctatc agtgaaggca tcataatcca
      721 cataactggt atcattccag ctagcataaa tgcaaaattt att
//
LOCUS       DARYXS010000211          752 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.212, whole genome shotgun sequence.
ACCESSION   DARYXS010000211 DARYXS010000000
VERSION     DARYXS010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..752
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.212"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..267
                     /locus_tag="TV193_002005"
     CDS             <1..267
                     /locus_tag="TV193_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEL1514145.1"
                     /translation="YNFSENGLGTFQNVFLAAEDISDLQIIMNSQLDNYIERLSAYIK
                     STGKTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEYDKGEHL"
     gene            264..>752
                     /locus_tag="TV193_002006"
     CDS             264..>752
                     /locus_tag="TV193_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate hydrolase"
                     /protein_id="HEL1514146.1"
                     /translation="MIKELEKVMIEDVEYSYDPEKEYIKDGHAFCKVCHERKDRKVME
                     FFDNKMIFKISCKCDRDREARKKEREKQMEIERLKKNCFNSIIQWSYTFENYQGEENQ
                     SLIIAKNFVKDYEQMKKENIGLLFYGSVGSGKTYLACSIANSLIEQYQIGVKIRNFAQ
                     LIN"
BASE COUNT          310 a           99 c          148 g          195 t
ORIGIN      
        1 tataatttta gtgaaaacgg gcttggaaca tttcaaaatg tgtttttagc tgctgaagat
       61 atatcagact tacaaatcat aatgaactca cagcttgata attatattga gagattatct
      121 gcatatatta aaagcaccgg aaagacctat aaagaccata aggcaacaat cctttcatgg
      181 ttttataaag atcagggaag gggcaaagaa gtgaaaacat caaatatccc gacatgggaa
      241 gaatatgata aaggagaaca cctatgataa aagaattaga aaaagtaatg atagaggatg
      301 tagagtattc ttacgatcct gaaaaagaat atatcaagga cggacacgcc ttttgtaaag
      361 tttgtcatga aagaaaagac agaaaagtga tggagttctt tgataacaag atgatattta
      421 agatttcttg caaatgcgat agagatagag aggcaagaaa aaaagaaaga gaaaagcaga
      481 tggaaataga acgattaaaa aagaactgct ttaactctat tattcagtgg tcatacacct
      541 ttgaaaatta tcagggagaa gaaaatcaaa gtcttatcat tgcaaagaat tttgtaaaag
      601 actatgagca gatgaaaaaa gaaaatatcg gactgctatt ttacggctca gtaggaagtg
      661 gaaaaaccta tcttgcctgc tccattgcaa atagccttat tgaacagtat caaataggcg
      721 ttaaaataag aaattttgca cagcttatca at
//
LOCUS       DARYXS010000212          751 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.213, whole genome shotgun sequence.
ACCESSION   DARYXS010000212 DARYXS010000000
VERSION     DARYXS010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..751
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.213"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            1..751
                     /locus_tag="TV193_002007"
                     /pseudo
     CDS             1..751
                     /locus_tag="TV193_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371017.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
BASE COUNT          271 a           89 c          145 g          246 t
ORIGIN      
        1 agtatttaga taaattctca aatcgaaatt tattggaaat attggataat ccaataaatc
       61 aattacagga ttataaatca attgagtcgt tagaaacata ttatgctagt gaaggaattg
      121 gtgggattaa actattaaaa atgttaggga atctaaagat ttctattctg ggatgtggtg
      181 gtggtggatc tcatattgca ttacaattag ctcaattagg agtgggaaga attcatttgg
      241 tggattacga tattgttgaa gaaaacaata tcaacagaca atccatgttc acatttaacg
      301 atgtcggaaa ttacaaagtt gattgtgtag ccaaaaatat tcagcaaaga aattctaaat
      361 gtttggttac caaaagcact tctaaaatga ttaatgtacc tgatgtaaaa aaaagaaata
      421 tctgaaagcg attgggtatt ctgttgcatg gatgaacctc cttatatagc acagaggatt
      481 gtaaatagag catgttattt attaaaaatt ccaagtatat actgttttag ccaacgtagt
      541 gcggggaaac ttttgttttg taatcctaat attgaagatt ctggctgtat tgattgtttg
      601 ttatctgaac aagataatga aaactttcaa aagctggtga caacgttcac tacctataat
      661 aggaaattgg taactgcaaa tatcttacca aatattttat tattgacatc gtgggtggtt
      721 aaacgatggt tagattgtgt aacagataaa a
//
LOCUS       DARYXS010000213          704 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.214, whole genome shotgun sequence.
ACCESSION   DARYXS010000213 DARYXS010000000
VERSION     DARYXS010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..704
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.214"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(1..674)
                     /locus_tag="TV193_002008"
                     /pseudo
     CDS             complement(1..674)
                     /locus_tag="TV193_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622164.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
BASE COUNT          230 a          150 c          100 g          224 t
ORIGIN      
        1 atagataatc aactcctcca gctttttaat aaaaaaatca acataaaaag ctgccttgtc
       61 atgataatat ttaagagagt gatgtgagct gcctttctat gttgtggaag agaaaggaaa
      121 atcttatctc gttcgataaa tgcttttccc aaaaaaatca tatcctcatc agataaaata
      181 gccaaacaac cgccaaaaat gtatagctca tactccgtcc actcttcaat actataaagg
      241 tattctgtca acaattgctt gtctgattct tcaattttaa catttggatc aagtgagtag
      301 atagcacttt taatgattaa ttcatttaat ctattataaa cagaaaaaat gtcatcaccc
      361 ttatattggc tcagaagctc cttcaatcca tctatatctg atgctgtttg tagctcggca
      421 accttggtgc ctaactgaaa aaaatcgctg actttatacc catttacagc atgaccaaat
      481 tcagcgaatg tcatatggat tcctgaaata gctaatagta gtttgtcagc tgccagcatg
      541 ctctggccat tttcaaactt agatagctgt gaaactgata aattgtctct agcaacgtcc
      601 tttagcctaa gtccacgagc aatacgaagc tccttataaa gctctcccag tctcatcaaa
      661 tctgtactat tcattatact ctctctacac atagttctaa tttc
//
LOCUS       DARYXS010000214          697 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.215, whole genome shotgun sequence.
ACCESSION   DARYXS010000214 DARYXS010000000
VERSION     DARYXS010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.215"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..495
                     /locus_tag="TV193_002009"
     CDS             <1..495
                     /locus_tag="TV193_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1514147.1"
                     /translation="GNNGVGKTTLLRCIAGLHKETKGEITLNGDVISGKKRQRLSAMV
                     MQDVNYQLFADSLVEECCLGNNCDNIQIDKVLGELKLIESKKSHPMILSGGQKQRLVV
                     ANAILSDKKILIFDEPTSGLDYEGMLAVSNELKKLSEKNYYIFVVSHDIEFINEICDR
                     VYEF"
     gene            518..>697
                     /locus_tag="TV193_002010"
     CDS             518..>697
                     /locus_tag="TV193_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1514148.1"
                     /translation="MSNKNWINTILDFASDCKGKLILSVVMASIGVFFSIIPYWSVYK
                     LMAVFIEQKATGEDVL"
BASE COUNT          264 a           68 c          146 g          219 t
ORIGIN      
        1 ggaaataacg gtgttggaaa gactacactt cttcgatgta ttgcaggatt acataaagaa
       61 acaaaaggag aaattacatt aaatggtgat gttataagtg gcaaaaaaag acaaaggcta
      121 tctgcaatgg ttatgcaaga tgtgaattat cagttatttg cagatagctt agtagaagaa
      181 tgttgcttag gaaataactg tgataatata caaattgata aggttttggg tgaactaaaa
      241 ttaattgagt caaaaaaatc acatcctatg atactttccg gtggacaaaa acaaaggtta
      301 gtagttgcaa atgcgatttt atctgataag aaaatattaa tttttgatga accgacatca
      361 ggattggatt atgaaggtat gcttgcagtg tctaatgaac taaagaagtt gagtgaaaaa
      421 aattactata tttttgtggt ttcacacgat atagaattta taaatgaaat atgtgataga
      481 gtttatgaat tttagataaa ggaggtggag aagttacatg agcaacaaaa actggataaa
      541 tactatatta gattttgctt cagattgtaa aggaaagttg attttatcag tagttatggc
      601 tagtatagga gtgttcttta gcattatacc ttattggtca gtatataaac ttatggcagt
      661 ctttatagaa caaaaagcaa ctggagaaga tgtattg
//
LOCUS       DARYXS010000215          696 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.216, whole genome shotgun sequence.
ACCESSION   DARYXS010000215 DARYXS010000000
VERSION     DARYXS010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.216"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(93..563)
                     /locus_tag="TV193_002011"
     CDS             complement(93..563)
                     /locus_tag="TV193_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1514149.1"
                     /translation="MLEVIKNWVNICVKEGDKILLLNRQHDDFPGWIQPGGKVNTSES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEDFEGKLLTKSREG
                     LPQWHAIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTITHLYD"
BASE COUNT          203 a          130 c          144 g          219 t
ORIGIN      
        1 atcaaggctt ttgcaggaga tttatgaaaa agaaaaattt aggatagtgt aagtataagc
       61 tagtttcctt aagaaaagct taactgaagc aattaatcgt agagatgggt gattgttttg
      121 acgacttttt tctccttgtc agaccaataa tgaaggcgtt caaaagatcc ttgtcgccag
      181 tagagtggta gcctttgtcg aatatcctct tgcatgtcta gcttatctag atcagcaata
      241 gcatgccatt gtggtaggcc ctctcgtgat ttagttagca gcttgccttc aaaatcttcg
      301 caaagaaagt cataataaac atagcgctca ggcttatcag gattggtaaa gcctgagatt
      361 ccctttaatt gcagatttaa ggcggttaag ccggtctcct cctttagctc acgcactgcc
      421 gcttcaaaaa aggattctga ggtgttaacc ttgccacccg gttggatcca gccaggaaaa
      481 tcgtcatgct ggcggttgag aagtaggatc ttgtcgccct ccttgacaca gatattaacc
      541 caatttttga tgacttcaag cattagttac ctcgttttta gttttatttt atcaaaaaaa
      601 gatcagtatg aatagctgag agatttattg atatggtcat aatggcttca gatagtttta
      661 ctgctgcttt agccatctgc ataaataata taaaaa
//
LOCUS       DARYXS010000216          672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.217, whole genome shotgun sequence.
ACCESSION   DARYXS010000216 DARYXS010000000
VERSION     DARYXS010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.217"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            54..455
                     /locus_tag="TV193_002012"
     CDS             54..455
                     /locus_tag="TV193_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1514150.1"
                     /translation="MAVKRKYIYVKGQKIYVPDEVYRAYKKGLNHETHLKRLDRKHGV
                     FRFGDFNTSIVDIADNTVDVEKIIETKMLIEDLYYALDSLNDEERKLIEALYFDDKTL
                     TEVAKQRDTNPMKISRLRNKILEKLRKFLDK"
     gene            complement(577..>672)
                     /locus_tag="TV193_002013"
     CDS             complement(577..>672)
                     /locus_tag="TV193_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL1514151.1"
                     /translation="ITDYIFYYNNKRIKAKLKGLSPVQYRTKSFH"
BASE COUNT          262 a           72 c          129 g          209 t
ORIGIN      
        1 tttttattca aaaaataagt ttgaaatttt tgataaaaag gagggcttta caaatggcag
       61 ttaaaagaaa atatatctat gtaaaaggtc aaaagattta tgtacctgac gaagtgtata
      121 gagcatataa aaaagggctt aatcatgaaa ctcatttaaa gagattggat agaaagcatg
      181 gcgtatttcg ttttggagac tttaacacaa gtattgtaga tattgcagat aatactgttg
      241 atgttgaaaa aatcattgaa acaaaaatgc tgatagaaga tctgtattat gcattagaca
      301 gtttaaatga tgaagagaga aaactaattg aagcactata ttttgatgat aaaactctca
      361 cagaagttgc aaaacaaaga gacacaaatc caatgaaaat cagtagatta agaaataaga
      421 ttttagaaaa gctgagaaaa tttttggata agtaaattaa gtagagggca gggaaacatc
      481 tctgtcctct atttttgaaa atttttcaaa aatagtgtta aaagttgtcc tgaaagtaag
      541 gttttgtact gacccccaaa agttggacac gacatattag tgaaaggatt tagttctgta
      601 ttgcacaggg ctaagtcctt ttagctttgc tttaatgcgt ttgttgttgt agtaaaaaat
      661 gtaatctgta at
//
LOCUS       DARYXS010000217          662 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.218, whole genome shotgun sequence.
ACCESSION   DARYXS010000217 DARYXS010000000
VERSION     DARYXS010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.218"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..>662)
                     /gene="speh"
                     /locus_tag="TV193_002014"
     CDS             complement(<1..>662)
                     /gene="speh"
                     /locus_tag="TV193_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeH"
                     /protein_id="HEL1514152.1"
                     /translation="IDKKIYSMIICLSFLLYSNVVQANSYNTTNRHNLESLYKHDSNL
                     IEADSIKNSPDIVTSHMLKYSVKDKNLSVFFEKDWISQEFKDKEVDIYALSAQEACEC
                     PGKRYEAFGGITLTNSEKKEIKVPINVWDKSKQHPPMFITVNKPKVTAQEVDIKVRKL
                     LIKKYDIYNNREQKYSKGTVTLDLNSGKDIVFDLYYFGNGDFNSMLKIYSNNERIDST
                     QF"
BASE COUNT          208 a          109 c           84 g          261 t
ORIGIN      
        1 aaattgagtt gagtctattc tctcgttatt ggaatatatt tttagcatgc tattaaagtc
       61 tccattgcca aaataataca aatcaaaaac aatatcttta cctgaattta aatctaaggt
      121 aacagttcct ttagagtatt tttgttcccg gttattatag atatcgtatt tcttaatcaa
      181 taactttcta acttttatat ccacttcctg agcggttact ttcggtttat tgactgtaat
      241 aaacataggc ggatgttgtt tacttttatc ccacacgttt ataggaactt taatttcttt
      301 tttttctgaa ttagttaatg taattccacc aaacgcttca tacctttttc ctggacattc
      361 acaagcctct tgtgcagata gagcataaat atctacttct ttatctttga attcctgtga
      421 tatccaatct ttctcaaaaa aaactgacaa atttttatcc ttgacactat atttcaacat
      481 atggcttgtt acaatatctg gagaattttt tatactatcg gcttcaatta agttagaatc
      541 atgcttataa agcgattcta gattatgtct attggttgta ttataagaat ttgcttgaac
      601 aacattggaa tataaaagaa atgacaaaca tataatcatg ctgtagattt tcttatcaat
      661 at
//
LOCUS       DARYXS010000218          621 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.219, whole genome shotgun sequence.
ACCESSION   DARYXS010000218 DARYXS010000000
VERSION     DARYXS010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..621
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.219"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..603)
                     /locus_tag="TV193_002015"
     CDS             complement(<1..603)
                     /locus_tag="TV193_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1514153.1"
                     /translation="MFKTTVRILNWSRKYSTRIKKGFILSFLNSVFIAMPIMLSIYVF
                     NLVLGNYYGSTTYGNKEIAIVTTIMIGLVLGRYITAYFKSVNQDSIGYEMSADERVQI
                     GDILKRVPLGFFQENNPGELTTAVTTDLSFFENYSMKMIDIVINGYIMALVMIISISF
                     LSWELGVVAVSGVVLSYFCLLLLRKHSEKNSVFYLNAQSKL"
BASE COUNT          233 a          116 c           65 g          207 t
ORIGIN      
        1 taatttactt tgtgcattaa gataaaaaac agaatttttc tcagaatgtt tacgaagtaa
       61 caataaacaa aaatacgaaa gtactactcc agaaactgct acaacaccca attcccaaga
      121 taaaaaagaa atactgatta tcataacaag tgccattata taaccgttaa taactatgtc
      181 tatcattttc atcgaataat tttcaaaaaa agacaaatct gtggttacgg cagtagtcaa
      241 ttctcccgga ttattttctt gaaaaaatcc caatggtact ctttttaata tatcaccaat
      301 ttgtactcgt tcatcagctg acatctcata accaatacta tcctgattta cagacttaaa
      361 ataagcagtt atatatctcc ctaaaaccaa tccaatcatt atagtagtca ctatggctat
      421 ttctttattt ccatatgttg tactcccata atagtttcca agaacgagat taaaaacata
      481 tattgatagc attattggca ttgcaataaa aacagaattt aagaaagata atataaaccc
      541 tttttttatt ctcgtactat attttctaga ccaatttaat attctgacag tcgttttaaa
      601 cattgcacta acctcctata t
//
LOCUS       DARYXS010000219          619 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.220, whole genome shotgun sequence.
ACCESSION   DARYXS010000219 DARYXS010000000
VERSION     DARYXS010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..619
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.220"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            186..>619
                     /locus_tag="TV193_002016"
     CDS             186..>619
                     /locus_tag="TV193_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1514154.1"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAKTLD
                     QLPNPEEQILYNYWDTNDQKAREYLGDLYGFLKSYLGELEKKAKEPGPAGPKGEKGEK
                     GEKGETGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKG"
BASE COUNT          245 a          110 c          149 g          115 t
ORIGIN      
        1 caatgtcaat aacatcaatc aaaaatcaga cgattaggat tttgattaaa aaaaaaaaaa
       61 aacgaaacca aagattgaaa ttgatagata gctattccca ctctaatagt ggacatgtta
      121 gaatttcctt tgggaaagga agttacagga aactaagact gtttctacca caaaaggaga
      181 gaaagatgag atacacatta aacaaaaaca agcgtgctcg taactacggg ctatgctcag
      241 cagctatcgc tctagcagca gtagccagcc taggaacagc tggcagcgct aaagctgagg
      301 aagcaaaaac attagaccaa ctacctaatc cagaagagca aattctatat aattattggg
      361 acacaaatga tcagaaagca agagaatatc ttggagacct atacggtttc ctaaaatctt
      421 atttaggaga gttggaaaaa aaagctaaag agcctggacc tgctggacct aaaggtgaaa
      481 aaggcgaaaa aggcgaaaaa ggcgagaccg gtccgatggg gcctcaaggc ctaaagggtg
      541 aggacggaaa agacggcgca cctggagaaa aaggagaaaa aggtgatccg ggtatccaag
      601 gccctaaggg ggaaaaggg
//
LOCUS       DARYXS010000220          604 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.221, whole genome shotgun sequence.
ACCESSION   DARYXS010000220 DARYXS010000000
VERSION     DARYXS010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.221"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            9..>604
                     /locus_tag="TV193_002017"
     CDS             9..>604
                     /locus_tag="TV193_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEL1514155.1"
                     /translation="MFIIKGEVSRKDLIREIEKAIKSDELGAFIGAGLSIPAGFCSWK
                     ELLREPAEEIGLDVEKESDLVNLAQYYSNSKKRTSIDDLIKGQFSQLVKPTENHKLLS
                     QLPISTFWTTNYDKLIEKALENNMKKPYVKTKDEQLRGTNHNFDAIVYKLHGDVETPE
                     DAVITRSDYEEFGYNKRKLFREVLEGDLLTKTFLFLGF"
BASE COUNT          238 a           62 c          123 g          181 t
ORIGIN      
        1 gggaggaggt gtttattatt aaaggtgaag tatccagaaa agatttgatt agagaaattg
       61 aaaaagctat taaaagtgat gaattaggag catttattgg agcaggatta tcaattcctg
      121 ccggattttg tagttggaaa gaacttctaa gagaacctgc agaagaaatt ggattagatg
      181 ttgaaaaaga aagtgatttg gttaacttgg ctcagtatta ttctaattca aaaaagagaa
      241 catcaataga tgacttgatc aaaggtcaat tttctcaatt agtaaagcct actgaaaatc
      301 ataaattatt gtcgcagctg cccatttcaa ctttttggac aacaaattat gataagttaa
      361 tagaaaaagc tttagaaaat aatatgaaaa agccttatgt aaaaacaaag gatgaacaat
      421 taagaggtac aaatcataat tttgatgcga tagtatataa gctgcatggt gatgtagaaa
      481 ctcccgaaga tgcagtaata acaagaagtg attatgaaga gtttggatat aacaaaagaa
      541 aattatttag agaggtttta gaaggagatt tgcttactaa aacatttcta tttttgggat
      601 ttag
//
LOCUS       DARYXS010000221          587 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.222, whole genome shotgun sequence.
ACCESSION   DARYXS010000221 DARYXS010000000
VERSION     DARYXS010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.222"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..>587
                     /locus_tag="TV193_002018"
     CDS             <1..>587
                     /locus_tag="TV193_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514156.1"
                     /translation="ATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAY
                     FGTDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLT
                     VLASKKRMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKVAREGADEALD
                     HKTVADAKLMEVWSAIDFNAFHELPYYEVQALFAS"
BASE COUNT          152 a          117 c          144 g          174 t
ORIGIN      
        1 gcaacaacct ttaatggtcc agaccctgtt cgcggcatgt cagctgaagc tatcacatgg
       61 gttaaggcta atagcaatat gtacaataat ttccgcatta attttgatgg cattggcaat
      121 tttggtgcct attttggaac tgatgatttg gctatttctc ggaatgtcga tgctatgctc
      181 ttatcagcca accccttgta ttatcacgat ttaggagctt atcgttttaa tcaaaagggt
      241 cagattgtag atagagacgg taagctcatt ggaacacaat accttgtgag tcgggcctat
      301 ttaactgtcc ttgcctcaaa aaagcgtatg tcaagctaca atcagctcaa aaaacactgg
      361 cagtctaccg gtaaggggat cagtagttct gaggagctct ttttagatgc ggcacaggga
      421 atgatcctag gctcgtccat ggctaaggtt gctcgagagg gggctgatga ggcactggat
      481 cataaaacgg ttgccgacgc aaagcttatg gaagtgtggt cggcgattga ttttaacgct
      541 tttcatgagc tgccctatta tgaggtgcaa gccttgtttg cttctta
//
LOCUS       DARYXS010000222          555 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.223, whole genome shotgun sequence.
ACCESSION   DARYXS010000222 DARYXS010000000
VERSION     DARYXS010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..555
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.223"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            21..>555
                     /locus_tag="TV193_002019"
     CDS             21..>555
                     /locus_tag="TV193_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514157.1"
                     /translation="MISVKKNLCRLGVLSSSLLLLTAATTPSVIAFADIQTSAIKNNT
                     DDADGMYFVQSYEMSVEDKELLVRNVKANHPTVSEDFIREVIERQLVGDYTLPEEETL
                     FRSAWQGVTVDQLGAALDVAIGMALTGGAGSIAAGVLRVGKREAVGRVKSILIKYGLG
                     KMIAEIPVDYMLNLLSPG"
BASE COUNT          178 a           74 c          127 g          176 t
ORIGIN      
        1 gaagggcatg gtgaatcaat atgatttctg taaagaaaaa tttatgtcgc ttaggtgttt
       61 tgtctagtag tttattactt ttaacagctg caacgactcc atctgtcatt gcttttgcgg
      121 atattcaaac aagtgccata aaaaataata cagatgacgc agatggtatg tattttgttc
      181 aaagttatga aatgtctgta gaagataaag aattgcttgt tcgaaatgtt aaagcaaatc
      241 atcctacagt ttctgaagat tttatcagag aagttattga aagacaatta gtaggtgatt
      301 atacattacc tgaagaagag actcttttcc gctcagcatg gcaaggggtt acagtagatc
      361 aattgggagc agctctagat gtggctattg gtatggcatt aacaggtgga gctggatcaa
      421 ttgctgctgg tgttttgaga gtcggaaaaa gagaagctgt tggtcgggta aaatcaattc
      481 taattaaata tgggctaggt aaaatgatag ctgaaattcc agtcgattac atgttaaatt
      541 tattatcgcc aggat
//
LOCUS       DARYXS010000223          541 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.224, whole genome shotgun sequence.
ACCESSION   DARYXS010000223 DARYXS010000000
VERSION     DARYXS010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..541
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.224"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..>541)
                     /locus_tag="TV193_002020"
     CDS             complement(<1..>541)
                     /locus_tag="TV193_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEL1514158.1"
                     /translation="SEIDQKIVRFKGFEDINDRDLRVGTFYYPKNEEKKHLILLVCGY
                     EESYLDFKSEIFFWLKNGYTVFCYDVRGTGRSQGRKVGGFTQFLKDCLLSIEYIEKNE
                     TFKKVSLVGHSMGGFAVATSLQFKTNIIDNSVIISGFDYPSEFVRKSVTNISFIFTWP
                     IEISIKLIEFLKFGNLSFLG"
BASE COUNT          189 a          109 c           53 g          190 t
ORIGIN      
        1 cccaaaaaag acaggttccc aaatttcaaa aattctataa gttttatgga tatttctatt
       61 ggccatgtaa aaataaacga aatatttgtt acactttttc ttacaaattc agatggataa
      121 tcaaatcctg aaatgattac actgttatct attatattgg ttttgaattg taacgaagtc
      181 gctactgcaa aacctcccat actatgcccc actaaagata cctttttaaa agtttcattt
      241 ttttcaatgt attcaatgga caataagcaa tccttcaaaa actgagtaaa acctccaact
      301 tttcttccct gacttcttcc agttcctcta acatcatagc aaaacacagt atatccattt
      361 ttcagccaaa aaaatatctc ggatttaaag tctaaatagg attcttcata tccacaaact
      421 agtaatatca aatgtttctt ttcttcattc ttgggataat aaaatgtccc tactctcaaa
      481 tcacgatcat taatatcttc aaatccctta aatctaacta ttttttgatc tatttcagaa
      541 a
//
LOCUS       DARYXS010000224          539 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.225, whole genome shotgun sequence.
ACCESSION   DARYXS010000224 DARYXS010000000
VERSION     DARYXS010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..539
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.225"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..>539)
                     /locus_tag="TV193_002021"
     CDS             complement(<1..>539)
                     /locus_tag="TV193_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514159.1"
                     /translation="TVFNAPSSVNNLSKEAIDFVKANKGLYHSYRINNDYIGNLGTYL
                     GDDELGISRWVDGKAGIGRHSLAAYRFNSKGQVIDRKGHPAAAQAPALATLRSRLTDY
                     RRLKKQYAASNGISSSEEFYLDQFQSRAVAQALEQTTQLAQEEIIARRKEAVAEAEAL
                     HQKTRDMPFFVSELSWAEL"
BASE COUNT          130 a          138 c          127 g          144 t
ORIGIN      
        1 tctagctccg cccagctcaa ttcactcaca aaaaagggca tgtctcttgt cttttggtga
       61 agtgcctctg cctctgcaac cgcctccttc cgacgagcaa tgatctcctc ttgggcaagc
      121 tgagtggtct gctccaaagc ctgtgcgact gctcgagact gaaattgatc aaggtaaaac
      181 tcctctgagc tactaatacc gttagaagcg gcatactgtt tcttaagccg gcgataatcg
      241 gttagtctgg atcttagggt agcaagagca ggtgcttgag cagcggcagg gtgaccctta
      301 cggtcaatca cctgcccctt tgagttgaag cgataagcgg ctaagctatg acgtcctatt
      361 cccgccttac catcaaccca tcttgaaatc ccgagctcat catctccaag gtaagtgcct
      421 aggtttccaa tgtagtcatt gttaatgcgg tagctgtgat agagtccctt gttggcttta
      481 acaaagtcaa tagcctcctt ggagaggtta ttaacagagc ttggcgcatt aaagacagt
//
LOCUS       DARYXS010000225          538 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.226, whole genome shotgun sequence.
ACCESSION   DARYXS010000225 DARYXS010000000
VERSION     DARYXS010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..538
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.226"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..>538
                     /locus_tag="TV193_002022"
     CDS             <1..>538
                     /locus_tag="TV193_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1514160.1"
                     /translation="DFEMHELANLIGTVFQNPKAQFFHTNSDAEIVFGLENNGMKPEK
                     IRRRYKEVVDELNIHDLTNRDMFSISGGQKQIIAFASIYAMNPKVYVLDEPTANIDKK
                     TIIKIGKIIEKLKKRGHTVIICEHRLYFLKDLVDRVFYVDQGEIKRTFSGDEFFRLEN
                     KERISMGLRTLEVPKLKN"
BASE COUNT          220 a           51 c          103 g          164 t
ORIGIN      
        1 aagattttga aatgcacgag ctagctaatt taattggaac cgtttttcaa aatcctaagg
       61 cacagttttt tcatacaaat tcggatgcag aaattgtatt tggtttagaa aataacggga
      121 tgaaaccgga aaaaataaga agaagatata aggaagttgt agatgaatta aatatccatg
      181 acttgacaaa tagggatatg ttttcgattt cgggtggaca aaaacaaata attgcatttg
      241 cttctattta tgcaatgaat cctaaggtgt atgttttaga tgaaccaaca gcaaatattg
      301 ataaaaaaac aattataaaa ataggaaaaa tcatagaaaa gctaaagaaa agaggacata
      361 cagtaattat atgtgaacat agactttatt ttttaaagga tttggttgat agagtatttt
      421 atgttgatca aggagaaatt aaaagaactt tttcagggga tgagtttttt agattagaaa
      481 ataaagaaag aatatctatg ggtcttagaa ctttagaggt accgaagtta aaaaatat
//
LOCUS       DARYXS010000226          499 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.227, whole genome shotgun sequence.
ACCESSION   DARYXS010000226 DARYXS010000000
VERSION     DARYXS010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.227"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(275..>499)
                     /locus_tag="TV193_002023"
     CDS             complement(275..>499)
                     /locus_tag="TV193_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1514161.1"
                     /translation="IQGQGEHGHKGHHGKDAKPSAPKADSKSTAKAMAPAAQKGTLPA
                     TGETNHPFFTLAALGVIASAGMLTLKGKKN"
BASE COUNT          120 a           92 c          117 g          170 t
ORIGIN      
        1 gaaattagcg catagaaaaa acgtatcagt tacgattata gtctagtttg tctttatgaa
       61 atatagataa cactgtacaa tccttttctt ttattgtacg actttataca aagaaaagcc
      121 cttggaaatt attttctaag gacttttttc aatttgagag gctggtgata gcctcttttt
      181 gaacttaggt catcttctta gggcaatgct gcctgaagag atgagaaaag ctgttactag
      241 ctcattgcct aaggggaaag gtgcaatggc tggtttagtt tttcttgcct tttaatgtta
      301 gcatgccggc gctagcgata acaccaaggg ctgcaagggt gaagaatggg tgatttgtct
      361 cccctgtagc tggcagtgtg cccttttgag ctgctggcgc catagctttt gctgttgatt
      421 tagaatctgc tttaggtgct gatggcttag catcttttcc atggtgaccc ttatgtccat
      481 gctcgccttg gccttggat
//
LOCUS       DARYXS010000227          482 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.228, whole genome shotgun sequence.
ACCESSION   DARYXS010000227 DARYXS010000000
VERSION     DARYXS010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.228"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(19..336)
                     /locus_tag="TV193_002024"
     CDS             complement(19..336)
                     /locus_tag="TV193_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514162.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKRAYQKREDSLSERRH
                     VLNDLINSEYQKMSVFLKRLDLSANAASDFFNELGRLKDQSNAEFHLFLKLGKILNNK
                     SLG"
     gene            complement(318..>482)
                     /locus_tag="TV193_002025"
     CDS             complement(318..>482)
                     /locus_tag="TV193_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514163.1"
                     /translation="VQDFQDYTQSKVSKLSALATDFENLNRDIQTVIDSKLETDRQLA
                     GEFRAWQTEL"
BASE COUNT          133 a          112 c           84 g          153 t
ORIGIN      
        1 ttagtcatcc tatagaaatt atccgagtga cttgttgttc aaaattttcc ccaattttaa
       61 aaagagatga aactctgcgt tggattgatc ctttaagcga cccaattcat tgaaaaaatc
      121 tgatgcagca ttggcagata ggtctaaacg cttcaaaaaa acactcatct tctggtactc
      181 agagttgatc aaatcattta agacatgtct tctttcagat aagctgtctt cacgcttctg
      241 ataggctctt ttctggcgta gaaagtcctg ctcggcatca tccatctccc gaagcttacg
      301 ataaatagcc acttcctcta caattctgtc tgccatgctc taaactctcc tgctaactga
      361 cgatccgttt caagcttgct atcaataacc gtctgaatat ctctattcaa gttttcaaag
      421 tctgtggcca aggctgacag cttgctgacc ttggattgag tatagtcctg aaagtcttgg
      481 ac
//
LOCUS       DARYXS010000228          471 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.229, whole genome shotgun sequence.
ACCESSION   DARYXS010000228 DARYXS010000000
VERSION     DARYXS010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.229"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..>471)
                     /locus_tag="TV193_002026"
     CDS             complement(<1..>471)
                     /locus_tag="TV193_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514164.1"
                     /translation="KLKGINVIALLKGYRRSYHRSSFFIKTGSIVMVLYLAIVSILGL
                     TDYLSMRQYIPTWESSKYYANMACAWSWSYEKDDDKFHEIVIPKLNNLWNSLDDSGAI
                     LFNAPNVRKEGMNDDEEYLNQQPFQGNYAYVNKNYLHIANLLDKDTNKIEQYKIH"
BASE COUNT          154 a           86 c           52 g          179 t
ORIGIN      
        1 atgtatttta tattgttcta ttttattcgt atctttatct aagagattag caatatgtaa
       61 ataattttta tttacatagg cataattacc ttgaaaaggt tgttgattta gatactcctc
      121 atcatcattc attccctctt ttctaacgtt tggggcatta aataatattg ctccactatc
      181 gtccaaacta ttccataagt tattcagctt tggaataaca atttcatgga acttatcatc
      241 atctttttca taactccaag accatgcaca agccatattt gcataatact ttgagctttc
      301 ccaagttgga atgtattgtc tcatactcaa gtaatcagtg agtcctaaaa tacttacaat
      361 tgctagataa agaaccataa caatcgaccc tgtttttata aaaaaagaac ttctatgata
      421 acttcttcta taacctttca ataaggcaat aacattaatt ccttttaatt t
//
LOCUS       DARYXS010000229          437 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.230, whole genome shotgun sequence.
ACCESSION   DARYXS010000229 DARYXS010000000
VERSION     DARYXS010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.230"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(68..139)
                     /locus_tag="TV193_002027"
     tRNA            complement(68..139)
                     /locus_tag="TV193_002027"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(104..106),aa:Arg,seq:ccg)
BASE COUNT          144 a           82 c           64 g          147 t
ORIGIN      
        1 attggtagat tttctgtcta acttttgggg tgcgggtcat ttaataggct tttttatatc
       61 gtttctatcc accttgaggg aatcgaaccc ccatctcaag aaccggaatc ttgcgtgata
      121 tccattacac taaaggtggc acctttaacc ataccactac agtatagcat aaaagtggat
      181 attttaaaat ccttttttct aaaaagatca caccatacac atgacgaaaa tgcatgtcat
      241 tattttctag tcatatgcat tttatcacta tatttttaat attttgacat catcagtggt
      301 tcaaatacag tttagttata ccataaatgt tcttgaaaaa acacattgat tacgaaaatg
      361 ctaccagaaa atgtcagttt ctccatgcat tggtatgcta aaaaaatact ataaaaagct
      421 gagcaattac ccagctt
//
LOCUS       DARYXS010000230          407 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.231, whole genome shotgun sequence.
ACCESSION   DARYXS010000230 DARYXS010000000
VERSION     DARYXS010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.231"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            257..>407
                     /locus_tag="TV193_002028"
     CDS             257..>407
                     /locus_tag="TV193_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1514165.1"
                     /translation="MKNRLEEIRKENGITQEELASILEVSRQTIGSLENGRYNPSIIL
                     AFKIAK"
BASE COUNT          171 a           52 c           77 g          107 t
ORIGIN      
        1 atgactactc aaaattaaga taaaaatccc aaaaatgaaa agcatagtaa agatatcatc
       61 acaaagagaa gcaagtgctc atcaacagac agaagtataa gaggaaaatg cagatataga
      121 ggagtcgtac atgtaaaaaa gtaagggcta gacctataag gaaacgattt tatggaaagt
      181 atacttgcca ttttctctaa aaaacattat actatatgta aagttagctt gtcattgttg
      241 caggaggtca ttaaatgtga aaaatagact tgaggaaatc agaaaagaaa atggaataac
      301 acaggaagag ttagcatcta ttcttgaagt atcaaggcag acaattggtt ctttagaaaa
      361 cggaaggtat aatccttcca ttattttagc ttttaaaatt gctaagt
//
LOCUS       DARYXS010000231          388 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.232, whole genome shotgun sequence.
ACCESSION   DARYXS010000231 DARYXS010000000
VERSION     DARYXS010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.232"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(55..127)
                     /locus_tag="TV193_002029"
     tRNA            complement(55..127)
                     /locus_tag="TV193_002029"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(92..94),aa:Thr,seq:tgt)
     gene            complement(135..216)
                     /locus_tag="TV193_002030"
     tRNA            complement(135..216)
                     /locus_tag="TV193_002030"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(180..182),aa:Leu,seq:tag)
     gene            complement(222..294)
                     /locus_tag="TV193_002031"
     tRNA            complement(222..294)
                     /locus_tag="TV193_002031"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(259..261),aa:Lys,seq:ttt)
     gene            complement(298..370)
                     /locus_tag="TV193_002032"
     tRNA            complement(298..370)
                     /locus_tag="TV193_002032"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(335..337),aa:Asp,seq:gtc)
BASE COUNT           98 a          119 c           85 g           86 t
ORIGIN      
        1 cccaccttgg caaggtggtg ttctaccact gaactacgtt cgcaactcta tcaatgccgg
       61 ctacatgact tgaacacgcg accctctgat tacaaatcag atgctctacc aactgagcta
      121 agccggccta tctatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      181 taaatctggt gcgtctgcca attccgccaa acccgccttt atgacccgta ctgggctcga
      241 accagtgacc ctttgattaa aagtcaaatg ctctaccaac tgagctaacg agtcctacgg
      301 tcccgacggg aatcgaaccc gcgatcttcg ccgtgacagg gcgacgtgat aaccgctaca
      361 ctacgggacc tattcataac ttatggga
//
LOCUS       DARYXS010000232          378 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.233, whole genome shotgun sequence.
ACCESSION   DARYXS010000232 DARYXS010000000
VERSION     DARYXS010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.233"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..>378
                     /locus_tag="TV193_002033"
     CDS             <1..>378
                     /locus_tag="TV193_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="equibactin biosynthetic protein"
                     /protein_id="HEL1514166.1"
                     /translation="NIGKTEVIIKAFNEMGRKNLDTDMRMLFSMTVGYASGRLTLSSP
                     LGPVLWEQSPNVPKIDLIPRFLDGNDNEGCSKPWLSILYEGDTYYKSYVYRNIWVEAI
                     MDDLKEFVFEDKSKKQSNSMKIQ"
BASE COUNT          139 a           41 c           77 g          121 t
ORIGIN      
        1 taaatattgg taaaacagag gttattataa aggcatttaa tgaaatgggt aggaaaaatt
       61 tagatacgga tatgcgtatg cttttttcta tgactgtggg atatgcgtct ggtaggctaa
      121 ctttatcaag tcctcttgga ccagttttat gggaacaatc acctaatgta cctaaaatag
      181 atcttatacc aagattttta gacggcaatg ataatgaagg atgtagtaaa ccttggttat
      241 caattcttta tgagggagat acatattata aatcatatgt atatagaaat atttgggttg
      301 aagcaataat ggacgatttg aaagagttcg tttttgagga caaaagtaaa aaacaaagta
      361 atagtatgaa aattcaac
//
LOCUS       DARYXS010000233          370 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.234, whole genome shotgun sequence.
ACCESSION   DARYXS010000233 DARYXS010000000
VERSION     DARYXS010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.234"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(<1..>370)
                     /gene="spel"
                     /locus_tag="TV193_002034"
     CDS             complement(<1..>370)
                     /gene="spel"
                     /locus_tag="TV193_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeL"
                     /protein_id="HEL1514167.1"
                     /translation="SVEGKFNVGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKG
                     AGKTIYMNVFIDGHKKDETSKYKITFEKSPVTFQEVDVRLRKSFMLNDEIKLYQYGSK
                     VLSGNWEFHGSGENEEGADLF"
BASE COUNT          114 a           82 c           48 g          126 t
ORIGIN      
        1 taaataagtc agcaccttcc tcgttctcgc ctgagccgtg aaattcccag tttccagata
       61 gaactttgga accatactga taaagtttta tttcatcgtt cagcataaat gattttctca
      121 atctaacatc aacctcctgg aaggtaacgg gagatttttc aaaagttatt ttatatttcg
      181 aggtctcatc tttcttatgc ccatcaataa aaacgttcat gtaaatcgtt tttccagctc
      241 cttttctctc attaacttta acgagaccac cattgattga atgtatttga tcttttgaaa
      301 atacttcagc cgataatgca agaccaaaaa catcgacatt atctccaaca ttaaatttac
      361 cttctacaga
//
LOCUS       DARYXS010000234          367 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.235, whole genome shotgun sequence.
ACCESSION   DARYXS010000234 DARYXS010000000
VERSION     DARYXS010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.235"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            complement(98..>367)
                     /locus_tag="TV193_002035"
     CDS             complement(98..>367)
                     /locus_tag="TV193_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514168.1"
                     /translation="FTGVNKIVFTWKGYDLYLDSTNANRLSALGWGSTALSGLIPDPI
                     VSKVLAAALGVVSASISYANAAGRGVIVAFVGTFPRGVIHWVASQ"
BASE COUNT          137 a           77 c           47 g          106 t
ORIGIN      
        1 actttccaaa aaatagtatt atttttaaat aatttatcaa caaacaccaa taatatcaaa
       61 ttaattgcta aacacagtat ttttaaatat aatgctatca ttgtgaagcc acccaatgta
      121 tcacacctct tggaaaagtt cctacaaagg caacaattac tcctcttcct gcagcattag
      181 cataagatat tgatgcagac acaactccta aagcggctgc aagtacctta gatactatag
      241 ggtctggaat aagacctgac aaagcagttg atccccagcc tagtgcagat aatctattcg
      301 cattggtact atctaaataa agatcatagc ctttccaagt aaaaacaatt ttatttaccc
      361 cagtaaa
//
LOCUS       DARYXS010000235          361 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.236, whole genome shotgun sequence.
ACCESSION   DARYXS010000235 DARYXS010000000
VERSION     DARYXS010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.236"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..>361
                     /locus_tag="TV193_002036"
     CDS             <1..>361
                     /locus_tag="TV193_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514169.1"
                     /translation="VRLKDNQSVFSFDSGKRIDEANLKNYVLVAVNGKELLPDHGIKL
                     SSLVNGQLHPYVKEPSRAYESLKDIIEETESEPFILYISSVYDDIVSRIDEYKMEASI
                     YVIGLVLSIVILATLLKI"
BASE COUNT          130 a           46 c           73 g          112 t
ORIGIN      
        1 tgtaaggctg aaagataatc aaagtgtatt ttcttttgat agtggcaaaa gaattgatga
       61 agcaaacttg aaaaattatg ttttggtagc agtaaatggg aaagaattac tcccagatca
      121 cggaatcaaa ctatcatctt tagtaaatgg gcagctacat ccatatgtta aagagcctag
      181 tagggcatac gagagtttga aggacataat tgaagaaaca gaatctgagc cgtttatact
      241 ctatatcagc tcagtttacg atgatatagt ttcaagaata gacgaatata agatggaggc
      301 aagtatatat gttattggtc tcgtcttatc tattgttatt ttagcaacgt tattaaaaat
      361 a
//
LOCUS       DARYXS010000236          359 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.237, whole genome shotgun sequence.
ACCESSION   DARYXS010000236 DARYXS010000000
VERSION     DARYXS010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.237"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..>359
                     /locus_tag="TV193_002037"
     CDS             <1..>359
                     /locus_tag="TV193_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1514170.1"
                     /translation="ILRNIRENLGEKLLSISMGNASKKTIGEYKSIIVDKVETIEMPL
                     AHIIPECVAALLLSLGIAIFMVFISWEMALAMFITVPFALMAYKKLMGNFNQLYEAQM
                     KSNKYMNSTIVEYISGI"
BASE COUNT          129 a           43 c           69 g          118 t
ORIGIN      
        1 aatcttaaga aatataagag aaaatttagg tgaaaaattg ctcagtattt ctatgggaaa
       61 tgcgtcaaaa aagacaatag gagaatataa gtcaattatt gtagacaaag ttgaaacaat
      121 tgagatgcct ctagcacata tcataccaga gtgtgttgct gcattgcttt tatcactagg
      181 tattgcaata tttatggtct tcataagttg ggagatggct cttgcgatgt ttattacagt
      241 gccttttgct ttgatggcat ataaaaaact aatgggtaat tttaatcagc tttatgaagc
      301 tcaaatgaaa tctaacaagt atatgaattc tacaatagta gaatatatta gtggtatag
//
LOCUS       DARYXS010000237          358 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.238, whole genome shotgun sequence.
ACCESSION   DARYXS010000237 DARYXS010000000
VERSION     DARYXS010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.238"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
BASE COUNT          117 a           80 c           56 g          105 t
ORIGIN      
        1 ttttacatcg tcaaatcatt agagaaacca tatatgctaa actgtcatag cctccactac
       61 tctctaggag atgatagaga tgacccgctt agtaacaagc ctaaaagtat cttgcaatag
      121 cttctaaagc tttgcttgca gtaaaaaagg tgagcgttct agcctaaatg cttgtcacac
      181 ataagcaagc ctcagacagc ctcaaaataa gcttttccat agcaagtctg tcacgctgga
      241 cgggataggg gtcttatatc tcattaatat ataaaataaa tctctcggcc acataataca
      301 ttgttaccta cagacgaatt cctcaattta gataacctaa gttcttcttc cctttaat
//
LOCUS       DARYXS010000238          357 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.239, whole genome shotgun sequence.
ACCESSION   DARYXS010000238 DARYXS010000000
VERSION     DARYXS010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.239"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            109..357
                     /locus_tag="TV193_002038"
                     /pseudo
     CDS             109..357
                     /locus_tag="TV193_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017839.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          115 a           51 c           70 g          121 t
ORIGIN      
        1 caaaagaatt ttattttgcg aacaactaca gaggtggaag agcgagccca tgacctcaaa
       61 gacaaaacaa aagctataga acaaaaaatg tttaagtttg atgaaataaa atcatcaatt
      121 tacacagact ttattgctat cttaggtgtg ttttcagctt ttgtttttgt tatgtttggt
      181 ggcatagatg tagcgagagc gatatttgac attggtagtg atcttcagac tctggactta
      241 tcaagaatga ttaccattgc aagcttaatg ttaattggta tattgacgct tatgtattct
      301 ttactgcttt ggatagctag aattacaggc aaaaattttg gtaactgcta ttcgtca
//
LOCUS       DARYXS010000239          349 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.240, whole genome shotgun sequence.
ACCESSION   DARYXS010000239 DARYXS010000000
VERSION     DARYXS010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.240"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
BASE COUNT          135 a           59 c           45 g          110 t
ORIGIN      
        1 taatctctaa taaactaatg ctatctagtc ttagctagca ataacctagt gcttctaaca
       61 acaataatca gctcaacaat ttttagcagc taccttttta aaaaaactgg gataaaaaga
      121 tttctcaggt aagaaaaata gagattcacc aaacagtgaa tctctatttt ttgaactgaa
      181 actccttttg tcccaaactc ataagatgta ttgactttat gagatgaaca atttgttaca
      241 cttgatttga tcatcggggc ttagaaaaaa tagtgaaaag aatcctcata attcgtgaaa
      301 aatataattt ctcacccaaa aatccaattc aagattgtat ttataagaa
//
LOCUS       DARYXS010000240          337 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.241, whole genome shotgun sequence.
ACCESSION   DARYXS010000240 DARYXS010000000
VERSION     DARYXS010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.241"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            <1..168
                     /locus_tag="TV193_002039"
     CDS             <1..168
                     /locus_tag="TV193_002039"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514171.1"
                     /translation="IVNSKYYISVTFMGGEIYTGVEQASKDNEEFLNRRKKAENKTTL
                     SKDIEVIYKEK"
     gene            171..>337
                     /locus_tag="TV193_002040"
     CDS             171..>337
                     /locus_tag="TV193_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1514172.1"
                     /translation="MVSDKDYNKLSEKVYDVDANKVTISVRKNTDILNRYVKILKAED
                     TPDNGMQAMAVV"
BASE COUNT          129 a           40 c           69 g           99 t
ORIGIN      
        1 attgttaata gtaagtacta tatatccgta acgtttatgg gaggtgagat ttatacaggt
       61 gtagagcaag cttcaaaaga caatgaggaa tttttaaatc gtcgaaaaaa agcagagaat
      121 aagacaacct tgagtaagga cattgaagtt atttataagg agaaatagta gtggttagtg
      181 ataaagatta taataaactc tctgaaaaag tatatgatgt tgatgctaat aaagtaacta
      241 tttctgttag aaaaaatacg gatattctta atcgttatgt caaaatcctc aaagccgaag
      301 atacccccga caatggtatg caagctatgg ctgttgt
//
LOCUS       DARYXS010000241          317 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.denovo.242, whole genome shotgun sequence.
ACCESSION   DARYXS010000241 DARYXS010000000
VERSION     DARYXS010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.denovo.242"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            88..>317
                     /locus_tag="TV193_002041"
     CDS             88..>317
                     /locus_tag="TV193_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002948623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein FlaR"
                     /protein_id="HEL1514173.1"
                     /translation="MKIVIIGYSGSGKSTLANVLGQHYNCAVLHLDKIHFASNWQERT
                     VSQMVSDISTFMSQKHWIIEGNYSSCLYEERM"
BASE COUNT          111 a           45 c           59 g          102 t
ORIGIN      
        1 tgcttgtcta aagaggattt gtccccaaaa tatattcttt atgctataat ataagtcaaa
       61 gtacagcatt gacaaaggag acaaagattg aaaattgtaa taattggcta tagtggttct
      121 ggaaagtcga ctttagcaaa tgttttaggt caacactaca attgtgctgt acttcattta
      181 gacaaaattc attttgcatc aaactggcaa gagcgaacag ttagtcaaat ggtctctgat
      241 atatcaacat ttatgtcaca aaaacattgg attattgaag gtaattattc aagctgtctt
      301 tatgaagagc gtatgag
//
LOCUS       DARYXS010000242        18476 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611952-rid16723983.guided.035, whole genome shotgun sequence.
ACCESSION   DARYXS010000242 DARYXS010000000
VERSION     DARYXS010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611952
            Sequence Read Archive: SRR18311089
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574818.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574818.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:29:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,055
            CDSs (total)                      :: 2,023
            Genes (coding)                    :: 1,936
            CDSs (with protein)               :: 1,936
            Genes (RNA)                       :: 32
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 25
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 34 of 87
            Pseudo Genes (incomplete)         :: 32 of 87
            Pseudo Genes (internal stop)      :: 27 of 87
            Pseudo Genes (multiple problems)  :: 6 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18476
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611952-rid16723983.guided.035"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: PA"
                     /collection_date="2020-11-17"
                     /collected_by="Pennsylvania Animal Diagnostic Laboratory
                     System, Pennsylvania Veterinary Laboratory, Harrisburg,
                     PA"
     gene            215..595
                     /locus_tag="TV193_002042"
     CDS             215..595
                     /locus_tag="TV193_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL1514174.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            595..1443
                     /locus_tag="TV193_002043"
     CDS             595..1443
                     /locus_tag="TV193_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1514175.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            1543..2754
                     /locus_tag="TV193_002044"
     CDS             1543..2754
                     /locus_tag="TV193_002044"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL1514176.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            2747..4614
                     /locus_tag="TV193_002045"
                     /pseudo
     CDS             2747..4614
                     /locus_tag="TV193_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            4719..6464
                     /locus_tag="TV193_002046"
     CDS             4719..6464
                     /locus_tag="TV193_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1514177.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISISKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            6464..8240
                     /locus_tag="TV193_002047"
                     /pseudo
     CDS             6464..8240
                     /locus_tag="TV193_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            8381..9730
                     /gene="gdhA"
                     /locus_tag="TV193_002048"
     CDS             8381..9730
                     /gene="gdhA"
                     /locus_tag="TV193_002048"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL1514178.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            9862..10272
                     /locus_tag="TV193_002049"
     CDS             9862..10272
                     /locus_tag="TV193_002049"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1514179.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(10463..12469)
                     /locus_tag="TV193_002050"
     CDS             complement(10463..12469)
                     /locus_tag="TV193_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL1514180.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            12918..14639
                     /locus_tag="TV193_002051"
     CDS             12918..14639
                     /locus_tag="TV193_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1514181.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            14641..15804
                     /locus_tag="TV193_002052"
                     /pseudo
     CDS             14641..15804
                     /locus_tag="TV193_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            15956..16732
                     /locus_tag="TV193_002053"
     CDS             15956..16732
                     /locus_tag="TV193_002053"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL1514182.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            16725..17690
                     /locus_tag="TV193_002054"
     CDS             16725..17690
                     /locus_tag="TV193_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL1514183.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEEIIEKALEIYFKEYIGQ"
     gene            17786..18445
                     /locus_tag="TV193_002055"
                     /pseudo
     CDS             17786..18445
                     /locus_tag="TV193_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
BASE COUNT         5502 a         3273 c         4313 g         5388 t
ORIGIN      
        1 ctttcaataa ttattcgttc aactttttgg gggcagtaca ccttggggtg tttttttgtt
       61 gtaggagatt gattggttga tagaaggcag gtttatattt attgaagtga caaggtctgg
      121 aaaaaaatta tccaaaatac tggtttaagt ctactttaat attcgtcaaa tctatgctat
      181 aatgggtcat atcgccatta aggagaacga aatcatgcaa ttagtacgtg aaaaagaatt
      241 tgtcaatcag taccattatg acgccagaaa tttagaatgg gaaaaagaaa atggaacacc
      301 ggaaacaaac tttgaagtaa cctttcagtt gattaataaa gatgtggaaa ataaagagac
      361 ggctattgtt tctgttttac aatttgtcat tgtcaaggaa gagtttgtga ttagtggtgt
      421 gatttcacag atggttcgta ttttaggacg cttggtggat aagcctagtg aatttacaca
      481 agaggaggtc gaatccttgg ctgctccatt attagacatg gtgaagcgct tgacctacga
      541 agtgacagaa attgccttgg atcgtcctgg tattaatttg gagtttaaaa gttaatgaag
      601 ttagcaataa taactgataa tacagctcac cttccagagc agttagcgga gcatgccgat
      661 atttttgtat tagacatacc tgtaatcata gatggtcaaa gctatgtcga aggacaaaac
      721 ctgaccattg aagcctttta ccaaagcatg agagaatctc aagagctgcc aaaaaccagt
      781 cagcccagcc tctctgaatt agatgattta ctagggcgtc tgtcaactga gcactatact
      841 catgtgattg gcttgttctt ggctagtggt atttcaggat tttggcaaaa tattcaattt
      901 ctcatcgagg agcaccctga gttgaccatt gcttttccag atagtaaaat cacctcagca
      961 ccattaggca gcatggttag aaatgcttta gagtggtctc agcaaggctt gagctttgca
     1021 gagattatgg ataagctaga agagcaaatc gctggaacca cagcctttat catggttgat
     1081 gatttgaatc atttggtcaa gggaggacgc ttatcaaacg gttctgcttt gctgggaaat
     1141 ttgctcagca tcaagccaat tcttcgcttt gatagtgaag gaaagattgt cgtctatgaa
     1201 aaggttagaa cggaaaaaaa ggccatgaag cgcttggttg atatcttaaa ggaattgaca
     1261 gctagtggtc agtacgaggt atcaattatc catgctagag cgcaggataa ggctgatatc
     1321 ttaaagcagc tcttgttgga taatggctat acctgccctg ttgaggaggt tcattttggt
     1381 gcagtgattg cagcccatct tggagaagga gctgttgcct ttggcataac gcctcttgtc
     1441 taaagaggct tgcccatgac caatctgagc ttgatatgac agcctttaac gggaagcata
     1501 tgacaaggct ctaggagctt ttaggtggta gattaaaaca tgataacatt aatgacaatg
     1561 ccttctgaat ttcagaaggc tttaccaata gtgaaaaaaa tcaagcaggc tggctttgag
     1621 gcctattttg ttggtggaag tgtgagggat agcttattaa acaggcctat tcatgatgtt
     1681 gatatagctg ctagctgcta tccagaggag acaaaggcta ttttcttaag aacaattgat
     1741 gttgggattg agcatggcac agtgcttgtt ttagaaaatg gcagtgaata tgagatcaca
     1801 acgtttcgaa ctgaggacgt ttatgtggat tataggcgcc ctagtcaggt atcctttgtt
     1861 cggtccttgg aagaggattt aaaacgaagg gattttactg tcaatgctct tgccttagat
     1921 gaggacggac aggttattga tatctttaat ggcttagagg acctaaagca taagcttcta
     1981 agagctgttg gaaggcctca ggagcgcttt gaggaggatg ccctgcggat tatgcgaggc
     2041 tttcggtttg ctgccagctt agattttgat attgaggctg agacctttga agcaatgaaa
     2101 agccatgctc ccttgctgga gaagatttct attgagcgct cttttattga gcttgataag
     2161 cttttaatgg ccccaaaatg gcgtaaaggt atcttagcta tggtggcatg tcaggccttt
     2221 aactatttgc caggcttagt gggcaaggaa gaagccctgc aaaagtacct gaaaacctta
     2281 gcagcggatt atgtgtttca ggacaatcat caggcttggg cctatttgct ggttatgctg
     2341 gagcttgatc agcctaaagc ctttttaaag gcttggaaaa cctctaatga ttttcagcgt
     2401 agggttacga tgatggcctc tctttatcag attcgccaag aaagacagct agaaaaatgg
     2461 gatatttact cgtttggcaa ggacttggct ttactcgttg acgatttacg acaggcacag
     2521 ggcttggtca gtgaggccaa gcgtgttgag agcttgtatc aggagctgac gatccatgat
     2581 aagcatgata ttgtggtcaa tggctcttat ctgattcgtg agcttggaat gaagccagga
     2641 ccacagctgg gaatgctttt aaatcagatt gagcaggcca ttgtagaggg gcgtctcgtc
     2701 aatcaaagag aacacattga ggcttttgtt agaagggaac tactaaatga gtgattttat
     2761 cgttgaacat ctgacgaagt ctgttggaga taagaccgtt tttcaggata tttcctttat
     2821 tattcatgct ggtgatcgca ttggcattat tggtgtcaat gggacaggaa aaacaacctt
     2881 gcttgatgtt atttctgaaa aagtgggctt tgatggtgac cgctcacctt tttcaaaggc
     2941 aaatgactat cgtatatctt atttaacaca ggagccggac tttgatgatg atcagtctgt
     3001 tttagatact gttctgtccc tagaattaaa ggaaatgcag ctgattcgcc aatatgagct
     3061 gttgatggct gactattcag atagcaatca ggaaaagcta gcagaggtga tgactgagat
     3121 ggatcgatta gatgtttggt cgatcgaaag tgaggttaag acggtcttat caaagcttgg
     3181 tattgtcaat ctggatcaga gagtgggtga cctgtccggt ggtatgagac gtcgggtaca
     3241 gctggctcag gtcttgcttg gagccagtga tttgttgctg ctagatgagc cgaccaatca
     3301 tttggatatt gataccatcg cttggttaag tcattactta aggacctcta aaaggactgt
     3361 tctatttatt acacatgatc gctatttttt ggatagtata gccacacgta tctttgaatt
     3421 ggataaggct catgtgactg aatatcaggg caattaccag gattatgtgc gtctgaaggc
     3481 tgagcaagac gagcgcgaag cagctcattt gcataagaaa aagcagctct ataaacagga
     3541 gctggcttgg atgaggacac agccacaggc gcgtgcgacc aagcagcagg ccagaattaa
     3601 ccgctttgaa cagttaaaaa aggaccttca tcaggaaagg cctatagatc aattagatat
     3661 ggcctttgaa gccagtcgta ttggcaagaa ggtcattaat ttcaaggagg tttcctttgc
     3721 ttatggtgat caggccatta ttgagcattt taacctgatc attcaaaata aggaccgtat
     3781 cggcattgtt ggagctaacg gtgctggaaa gaccaccctg cttagcttga tgactggtga
     3841 cttaaaacca acagctggtc agctagagat tggcgagacg atccgtattg gttatttttc
     3901 acagcaaatc aaggatatgg acggcagcaa gcgcgtgatt agctatttgc aggaggtggc
     3961 agatgaggtc aagaccagtg ttggcaccac tagcatcagt gagcttttgg agcaatttct
     4021 ttttccgcgt tctagtcatg gctccttaat cgctaagcta tcaggcgggg agaaaaaaga
     4081 ctgtatttgc taaagctctt gatcgaaaag cccaacgtcc tgctgctgga tgagccgacc
     4141 aatgatttgg atattgcaac cttgacagtg ttggagcatt ttttagctca atttgctggt
     4201 ccggtcatta cagtgagtca tgatcggtat ttcttggata aggttgcaac aaaagtattg
     4261 gcttttgagc atggagctat cagagaatac tatggtaact atagcgacta tttagatgaa
     4321 aaggcttttg aagcagaggt catagagcct gctgtcagtg agcaaaaagc tggcactgac
     4381 catcaggtca cctctaaaaa gagaatgtcc tatcttgaga aaaaggaatg ggcagctatt
     4441 gaagaaaagc tagctgctat cgagcaacaa atagctacta ttgaggagca aatgctcaga
     4501 gcggcaagtg attacgacca attggcacaa tatcaaaagg agctggatca gcggaatctt
     4561 gagctgcttg aagcctatga gcgctttgat tacctaagcg aattagaaga ataattaatt
     4621 atgtgtcaat ttcatatttt tgtgttaaac tagttataga caaaaagaag tgctagcttg
     4681 cgcttctttt catatcacta ttatttggga ggaaatgaat ggctttaatt tggtcctatt
     4741 taaaaacaag acctaaatgg atttgtttcg atattgtggg tggcttgtta tttgttctgg
     4801 tcaatctggg gctaccaaca atattggctc gtatgattga tcaaggcgtt atgcagcagg
     4861 atcaaagggc tctttatttt tgggctctga tgatgtttat tatcgtactt ttaggtgtca
     4921 ttggacgggt gattttatcc tatgcttcgg gtaagctaac caccaacatg atcaaggatt
     4981 tacgtaatga catgtatagc tgcttgcagg attattcgca ttcggaatat gaaaaaattg
     5041 gcatagcctc cctggttact cggataacaa atgatgcctt tgttttgatg caatttgctg
     5101 aaatgtcctt gaggctgggt gtcgtaactc ctttgatgat gatcttttca gtggtgatga
     5161 tctttttaac cagtccatca ttggcttgga ttgtggctgt tgccatgcct tttttagtta
     5221 ttgtggtgct ttatgttgcg ataaagacaa gacccttatc agaaaagcag caggagagcc
     5281 ttgatcgtat taaccaattg gtgcgtgaaa acctgacagg tctgagagtt attcgagcct
     5341 ttgcaagaga agactttcaa gaagagcgct tcaataagcg caatgatcac tattctggaa
     5401 tctcaaagcg actatttacc ttgacaggct taacagagcc cttatttgtg caaattatca
     5461 ttgctatgat tgtggggatc gtctggtttg ccttggatcc cttggcaagg gggcagttta
     5521 agattggtga tttggtggcc tttatcgaat atagctttca tgctcttttt tcatttttaa
     5581 tgtttgccaa cctctttacc atgtacccta aaacagcagt gtcaagcaag cgtatcaagg
     5641 aagtgctgga tatgccgatt tcgatttcta aaaatgaaga tggtataaca gcgttcacaa
     5701 cacgtggtta tctagaattt gataacgtga cctttgccta tccgggtgaa acggaaagtc
     5761 cagttttaca taacatctca tttaagacta ggcctggaga gaccattgct tttatcggct
     5821 cgacaggttc aggaaaatca tctttggtta atctgatccc acgattttat gacgtgacct
     5881 tagggagaat cttggttgat ggcattgatg tcagggatta tcaattaaaa gcgctgcgtt
     5941 ctaaaatcgg ctttattcct caaaaagccc tgctatttac aggaaccatt gaggaaaacc
     6001 taaaatatgg taagtcagat gccagccaca gtgagcttga gcaggcaaca gaggtttccc
     6061 aagcgaagga ctttattacc agtcgtgaaa agggctatca aacccatcta gctgaggccg
     6121 gcagtaatct atcaggaggg caaaagcagc gcctgtctat tgccagagca gtggtcaagc
     6181 agccagacat ctatatcttt gacgattcct tttctgccct agattacaag acagatgctg
     6241 aattacgcag acggctgaaa gaggtgacac aagatgcaac ggtcttaatt gtggctcaaa
     6301 gggtgggcac gattatggat gctgatcaaa tcattgtctt ggatcaggga gaaattgttg
     6361 gccgaggtac acatgaggaa ttgcttacaa gcaatgccat ctatcgtgaa attgccaatt
     6421 ctcagctaaa caaggaagac atgacaaaag aggaggggga ttaatgactg aaaagcatgt
     6481 gtttagaaga atttggacct accttagtgc ctataggctc tcactaataa ctgccattat
     6541 tttaaaaata gtcagtgctg tgatgagtgt cttagagccc tttgttcttg gcttggtgat
     6601 aacagagcta tctgcaaacc tattagacat agcaaaggga gtctctggtg caggcattaa
     6661 taaaacctat atcgcctttc ttttagctct ctatatcatt agggcccttg tttacgagtt
     6721 aggctcttat ggttcaaact attttatgac aagggctgtg caatcaagca tttgtgatct
     6781 tcgtcgagac ctcagtcaaa aaattaatcg tatccctgtg tcttattttg ataagcatca
     6841 gttcggcgat atgctaggcc ggtttacctc tgatgttgag acagtctcta atgccttaca
     6901 gcagtccttt ttacagattg ttaacgcctt ttttaccctt attttggtgg ttggcatggt
     6961 cttgtatatt aatgcccccc tagcctctgt tgtgattatc gctatcccgt tgatatatgc
     7021 tgcttctcga tttgttttaa aaaaatcaca gccttatttt aaagcgcagg ctaatatttt
     7081 gggagaaatg aatggctttg tgcaggaaaa tttgaccggc tttaatattt taaaactgta
     7141 tggtcgtgaa gaagcctcaa aggaggaatt tcaccagatc actgagcgat tacaagaagt
     7201 aggctttaag gccagcttta tttctgggat catgatgcca gttctgcatt ttatttcaga
     7261 ttctgtttac atgattgttg ccttaatcgc tggcttacag gtgatagcag gccgcctgac
     7321 aatcgggaac aaacatgcaa gcctttgttc agtacatttg gcaaatcagt cagcctattc
     7381 agaccataac acagctggct ggtccactgc aaagtgccaa gtcatcctta gaacgtatct
     7441 ttgcagtgct tgatgaggca gatgaattga ctattgccca agagcattta gaacatgatt
     7501 taacaggtca ggtgtccttt aatcaggttg attttagcta tacagcagac aatcctctga
     7561 ttagaaattt caatttagag gttaagcctg gtgagatggt agctatcgtt ggtccgacag
     7621 gagccggcaa gaccaccctg attaatttat taatgcggtt ttatgatgtg aatgagggct
     7681 ctatcacagt tgatggtcag gacattcgtc agttgtcacg tcaagcctat aggcgtcagt
     7741 ttggtatggt gctgcaggac gcttggctct ttgagggcag cattcaggaa aacttgcgct
     7801 ttggtcattt agaggcgact gatgaacaaa taattgaggc tgctaaggct gccaatgttg
     7861 atcatttcat taggacattg ccaggtggct atcatatggt gatgaatcag gaatctagca
     7921 atatttccct ggggcaaaag cagctgctga ccattgctcg agctctctta gcagatccaa
     7981 agctgctaat cctagatgag gccacctcgt ctgttgatac acgtttagag cttttgattc
     8041 aaaaggcgat gaagcgatta atggttggca ggactagctt tgttattgct caccgcttat
     8101 caaccattca agaggcggat aagattttag ttctaaaaga tggtcagatt atcgagcagg
     8161 ggaatcatga cagcctatta gctgctaagg gcttctatta tgagctttat catagccaat
     8221 ttaagaccag tcagtcttaa aaagcttagg gtcttggaat gaatcgttcc aaggctcttt
     8281 taatttgctt tagatcatag taaaagcttg acatcaaaat tcagaaaatt tataatattg
     8341 actatactta aaatagaatg aagaagcgag aggatatata atggtatcag caaaagacta
     8401 tgtagccagt gtttttgata aggtcaaaag ggataatccg catgagactg aatttcttca
     8461 ggcggtcaag gaggtatttg attccttgat tcctgttttt gaaaaatacc ctaattatat
     8521 tgaggaaaat ctattagagc gcttggttga gcctgagcgt gtgatttcct ttagggtgcc
     8581 ttgggttgat gaccagggca gggtccaagt taatcgtggc taccgcgtgc aattttcatc
     8641 agctatcggt ccatataagg gagggcttcg ctttcaccct tctgttaacc agtctatagt
     8701 taaatttctt ggctttgagc agattttcaa aaatgctctg actggtcagc ctattggagg
     8761 aggaaaagga ggatcaaatt ttgatcctaa aggcaaatca gacctagaaa tcatgcgctt
     8821 cacacaaagc tttatgacag agctgcaaag gcatattgga cctgaccttg atgttcctgc
     8881 tggtgatatt ggtgtagggg ctcgcgaaat tggctattta tttgggcaat ataagcgtct
     8941 taatggcttt aagaatggtg tgttgacagg aaaaggctta gcttatggtg gctctttggc
     9001 tcgcacagag gccacaggct atggtgtggt ttattttgct cagcaaatgc tggcggctaa
     9061 ggggcaggac ttggctggta aaacagctat tgtatctgga tcaggaaatg ttgccattta
     9121 cgcaacggaa aaattgcagg ccttaggtgt taaggtatta gcagtgtcgg attcctctgg
     9181 ttacgtttat gatgataagg gcattgatct tgagacccta aagcaaatca aggaagtgaa
     9241 gcgtgagcgt atcaagacct atctagagag tcacccggct gctgtgttta caccggctgg
     9301 tgagggatcc atctggacta ttaaggcaga ccttgccttt ccatgtgcga ctcaaaatga
     9361 gctacaagag gcagatgcta aagccttgat tgagcatggg gttaaagctg ttgtcgaagg
     9421 ggctaacatg ccctcaacct tagaggctat tgagcaattt cagcaggctg gggttctttt
     9481 tggacctgct aaagcagcaa atgctggcgg tgtagcagtt tctgcgctgg aaatggcaca
     9541 aaatagcgga cgtaccgcat ggacctttga agaggtggat catcgattgt atgacatcat
     9601 gaaggctatt tatcaaaaag cagccgctgc cgccaaggaa tgtggtcaag aaggcaacct
     9661 agtggtggga gctaatattg caggctttct caaagttgct caggccatgt cagcacaggg
     9721 aatcgtttaa gagctgtggc tggtatatgc tgaatatatc agtagggtta gcacattaat
     9781 cttagctcaa tgacgttaag atatacgatc ggtcatctag acaatgcatg ccgattagag
     9841 caatgaatca aggagaagct gatgatcaaa aaaatcgtga aggacacctt tttcttgcag
     9901 caaaaagcac agccagcaac gaaaaaggac ctttggattg gtcaagacct gcaggatacc
     9961 ttagcttatt atcgtgatag ctgcctgggg ctggctgcta atatgatagg ggaaaacaag
    10021 agggttatta ttattagcat gggctttgtg gatttggtga tgtttaatcc tgtattaatt
    10081 gctaagcgtg aagcgtttga ggcagaggaa tcctgcctat cactaatcgg ccaacgtaag
    10141 acaaagcgtt atcaggagat caaggttgat taccttgatg cacattggca caagaaatcc
    10201 ctgagattga caggcctgcc tgcacaaatc tgccagcatg agctggatca tctggagggc
    10261 atattgattt aaatcatgac cacccgttag tgaactgcac cccaaaagtt agacagaaaa
    10321 tctaacgaat gagggcagtc catagatggg tggtttattt gtcttgctca acaggtgcga
    10381 aacaaataaa cgtcacataa atcagaaaac cggctgtatg cttaagatac agtcggttat
    10441 tgctgttatg gctaggacga ttttattggc cttccttttt cttgaaaagg ctagtaccag
    10501 ttaaggttag tagtcctagg attgtcatgg cagcagcaga atgctggctt gttcctgttg
    10561 ctggtaaggc agcattagct tgctttttag ctgctagagg cttgatgctt gtggcaggat
    10621 tagcattttg agcaggcgta aataggtcag agacaagctc agtagcaagc accttgccct
    10681 cacgattctt aaagacgcgg ttgatgatct cgtgcttgcc ggtatgatca ctttgagtag
    10741 agccttcaag actggcagtg acataggttt tcacaccgtt aataccagca cttacagtct
    10801 ttccagctgc ttcaaggtcc ttgatgtatt cgataaagac ctcagtatca ggattaatgg
    10861 ctcctagtag cttagcgtcc ttaaagacgg agaagccatc accaccgcca tataggaagt
    10921 cgttgatgat tagggtgtat tgagctgctg gatcaatttc ttcaccatta tctttataag
    10981 cctttactac cttaaacggt gttgaaggat cgttagcctc attagctgta taagtgtatt
    11041 tgagtccaga catttgaagg aagtattttt ggtcttcatc gtattgttgg ttcaagacat
    11101 catagatttg ttggccagtc atttgaacga cctgaagaat attgccaaat ggttgaacag
    11161 cctgtgcagc tccccaggta atggtttgat cctctttgac caccaagtca gcgcgaatac
    11221 cgccattatt tgtcatggca aaatcaacat gagggaaggt ttttctacca atggttaatt
    11281 gggcagttgt tatcaaattg ccaacaggag attccttgtc ttcgttttct gttttagaaa
    11341 tcgttgaaga ggtagctgct gtaccgatct ttagctcggt aacggttttg acaatgtcat
    11401 tggcttgatc aacaatggct tgaatgtcgg cattgcctgt ttttatgcca ggagcaacgg
    11461 caatgacctt tgcttcagga gtggctacaa aatcattgag gtcagtgtct agtgttccac
    11521 gaacatctgc ataggctttc ccctgtgaaa cagcctgaac gacacgtgtt gtgccaatgg
    11581 taccgttggt gtattggtgg ttgtgaccag caaagacaat atccacacta tgctcaggat
    11641 aaagctggtt aaccttttcc ataactgctg ccatctcatc atgaactacc ccgttatcac
    11701 ttgttgctgg gatatgagct aggacaacaa tcgcattgac ctgctgctct tggagctctt
    11761 tagcatattt aacgatggtt tctgcagagt ctaggtaatc atattgttca taattttgtt
    11821 ttaggacaag gtttggaatt tctgttgtca caacaccgat aaagcccacc ttgactgact
    11881 tatcattaac tgggacttct ttgacagcat aaggcttcca gccaaaagga atcgtgttgg
    11941 tctccttgtc aacgacattt gcaatgacaa gggtttgatt tgaagcttca tgctcgtatt
    12001 gcttagtaat gtcgttgata gctgagtctt cagcaggtgc agtgcctgtc atgatacggt
    12061 tgaattcagc taagccctca tcgaattcgt gattcccaag ggttccgtat tcaaagccca
    12121 tctggttgaa taccttaacc gttggctcgt cctgtaatag tccagaatta gcaggactag
    12181 ctccgaccat atctcctggt tgaacacgaa tgcttgtccc atctgggctt gtttgcttaa
    12241 agtcagcctc tgcatcgtcc agataagcag ctaattgtgc tgcggtacca gcgttagata
    12301 cctttccttc tggcatgtag gcagagccgg ttgtgtctaa ggcaccatga aagtcattga
    12361 caccaagaaa ttgcacgtct acctgatcgg cctgcacgcc ggttactagc atagaaactc
    12421 cggcaaagac accaagaaca ctacttttta aaacaaaatg ctttttcata aacgctccta
    12481 aaagtttaaa gtattgtcac aagttaagtg tactattatt taaatgagaa ttcaacaaaa
    12541 attaataaaa aagctaacaa aaattcaacg atagcgtttg ctaatcactg aaaacgttta
    12601 aaatgcaaac attggaagcg ttttttgtaa aaaaatagaa gaactatcca aaaaaggctt
    12661 tacaagccca gtattctatg ataagatgtt aggcagatta aaagaaagga gaaattaata
    12721 atgatccgtt tcattcaact atttaaccat tattacgata gtctcctttc taaccaaaac
    12781 agttagtttc ttttagtttc actaaataga aatagtagag cccgcggtag gaaggatatc
    12841 ttattgcggg ctttttgtgt gcaaaaatcc tattttaaga cagcttgaaa taggttagtt
    12901 cagaaatgga ggatatgatg ctgaccttaa ttgttcaaca tattaagcaa aagaaatgga
    12961 tttatatcct tattgcaatg actttagtga tatatgatgc ctcacttgtg ataccaacaa
    13021 gggttattca agacttggtt gatttgatgt caaggcatca gctaagctca ggggcattgg
    13081 tgaggcatgt tatcattctt ttggctacgg cagtagtgtc ttatggggtt gcttatttgt
    13141 ggcatcttca tttatttcag gaggcagttc attttaagtt tgatattcag cagcgtgcct
    13201 ttcgaaagct tgtttttatg agaacgcctt tttatgagaa atttcgctca ggtgacatga
    13261 tcacgcgttt ttcaacagat gtcgaagcac ttatggacct tatcggctat ggcttgatga
    13321 ttatcctata tgctggtggt atgattgctt ttattattcc gaccatgttt ttgatttctt
    13381 ggaaaatgac cttgatagga atagtaccga ttttgcttat gatggtgatg atctatggtg
    13441 tgacgaaaaa gcaagagcat ttggttgaag aggcgcgtga ggcgatttca agccttagtg
    13501 atgaggtact agaaaccgtt gagggcatta gagtgatgcg tgcttacagt aaaaaagatt
    13561 atttggcact tcattttgct caaaagactc agaatttggc agataaatgg aatcaggtgg
    13621 ccaagtatcg tgccttgtac tttcctcttt acagcgtcat gattgccatt agtacagtaa
    13681 tcattttaat ggtaggccta cagctcatag caagctcaga ggtaacactt ggtcaagtca
    13741 ttgcgctgca gctttatctg gtgtctttgg tggagccctt tggcatgctg tcagacttta
    13801 ttttggttta tcagacagga aagacctctt ttggtaagat taatgaactc atcgaaacaa
    13861 gtgatgatat ggagcctgat ggccagcttg agttagagag ctttgatcag attgctttta
    13921 tagactatag ctttacctat gccaatagtt ctaggcctag cttagaaaag atcaatttaa
    13981 ccctgaaaaa gggacaaacc ttagggattg ttggtaaaac aggctctggt aaaacaaccc
    14041 ttgtcaggca gtttttgaga caataccctc ttgggcaggg gcagctgatg attaatcatc
    14101 gtagtgtctt ggattataag cgtcaatcac ttgagcgtca aattggctat gtgccacagg
    14161 agcatatcct gttttcaaaa acggttgctc aaaacattgc gatggggaaa aaggcagcta
    14221 caactgagga aatcttggag gcgattgaaa ctgcggcctt tacgcgtgat gttcaaggaa
    14281 tggcaaaggg cttggatact gagattggag agcgtggtct gtctatttca ggaggtcaaa
    14341 agcagcgtat ttcgattgcc agagcctttt tgtcccagcc agatttgctg attttagatg
    14401 attccctgtc ggcagttgat gctagaacag agactgatat tattcgacac attcaagacg
    14461 aaagaaaggg aaagacaaca cttattgtta gccatcgctt gtctgcgatt cagcatgccg
    14521 attgggttat tgttctggat caggggcaga tagtagagga aggtcagccc caacaacttt
    14581 tagctcagaa gggctggtat tatgaacagt accagcgtca gcaggctcag gaggtttaag
    14641 atgaccctat ttataaaatt aataaaagaa attaaagctg tgaccttggc tttttccctg
    14701 gcaataggct ttttgctagt ggcaacagct ggaggtcaga tggctccctt attgttgcaa
    14761 caaacgattg atcattactt gactccgata gctagaggaa aagaggtacc gattgaaggc
    14821 tttcagcgct tgctcctgct gtatttgctg ttaattgtga taacagcagt tttgcgttat
    14881 atctcttatc gaatgctggt ttattcctct aataggatcg ttgctaatct tcgtaatcga
    14941 gcctttgatg tcatgcagag gctgccgata gcttattttg atcatcagcc tgcaggaaag
    15001 attgcaacta ggattgttaa tgatactgaa accctgaaga atcaatttta tgataacctt
    15061 ttgtctcaaa ttattgtcag tctttcacaa attattttta tttatgtggt gatgatttac
    15121 cttgatgtga agtcaggctt gctgttgctg cttattatgc cactctttta tggcatgcaa
    15181 tggctgtata aaagcttgac tgaccagcca atgaaggatt tttatcaggc taggagcgct
    15241 gtcaacacac aagtcaacga aaccatgaat ggtgtttcta ttattcagct ttatcatcaa
    15301 gaggatacga tcttagagga atttgaagag cagatccacc agatgaaaac agctgatgat
    15361 aggattattt ttgcagagtc agttgcttca tggaccctga cggaattggt aaagtatggc
    15421 atgattgccg ctattttggc tgttattggt taccagttct tgcaggggag atcaggcatc
    15481 acagttggta agctctttat ttacgtcaat tatttgctgc gcttgtttga tttattaagt
    15541 atgctggtta ggcagctacc taatattcag cgctcaacag cgacaggaac gcgcctaatg
    15601 aagctgcttg aggcgcagac agagccggat aaagcacgag caattgagct aacagatggt
    15661 actgtggatt ttaccaaggt gtattttgct tacgaaaatg gcaagacagt tttatctgat
    15721 attaccattc atgctgataa aggggagacg gttgccctag tagggcatac tggctctggg
    15781 gacaatgcta taatgatgat agtacaataa atccaagtaa aatcaatggt taaaggcttc
    15841 cgcaaaactt ttaaacttga tgatggattg aggctatcat ctttttttat atctaaaatt
    15901 atataaaagt atagcataaa atgaaatctc tgtatagaga agaaggaggg actttatggc
    15961 agaagtgata accatagcca atcgaaaagg cggagttgga aaaacaacta caactctaaa
    16021 ccttgcctat tcactaaaag aactggggaa aaaagtatta gtcattgacc ttgatccaca
    16081 agctaatctt acaagatgtt ttgatatggg aaatacagaa aatataaaaa ccatagggca
    16141 tttgttaatg gtagaactgg aggaagaaga aagctatttg gtagagggct ataccaaatc
    16201 ttatgatgag atagatatta tcccctcaag cattttctta tccgccgttg aaacacaaat
    16261 gagagcagaa acaggaagtg aacgtatatt atcggaaatt attaggaggg taaaagagaa
    16321 ttatgactat attctcatag atacatcacc atcacttagt gttttgacta taaatgctct
    16381 ttgtgcctca gacagtgtcc ttatagtagc ggatacacag ctgttcgcag ttgttggaat
    16441 caatgaactt ttaaaaactg ttcaaaaaat aaaaaagaga gtgaatccga aactgaaagt
    16501 gcaggggatt ttactaacca tgtgtgagaa tagaaccaat ctgtccaaaa cactgatgga
    16561 gcaagtagaa gaaatgttcc aaaagaaaat caaggtcttt caaaccaaaa ttccgaaaac
    16621 agttaaagtt ggggaagcca tctatagcgg gcaaagcata aaaaaatatg caaaaggcag
    16681 tagtgtagac attgcctatg acaatctggc aaaggagatc tgctatgagt aaaaaacttc
    16741 taaagagaga aatcaccgat gccgtagatt ttttgcttga tgatggaaat gccttggaac
    16801 aaggaaatat acagaatata gaacttgatt tgcttgaaaa ttatcataat catccgttta
    16861 ctttatatac aggtaagaga ttagacgata tggtagagag cattaaggaa aacggagttc
    16921 ttaatccaat tatcgtcttg aaaaaagata acaactatga aatactttcc ggacacaata
    16981 gagtaaatgc agcaagaatt acaaaaataa aaagtattcc ttgtattgtt aaagaaaatc
    17041 taacggataa agaagcctat acctatgtaa ttgaaacaaa ccttatacag cgttctttct
    17101 ccgatttact gccgacggaa aaagcccttg ttcttaaaat gagatatgaa aaaatagcaa
    17161 gtcagggcaa gagaaatgat ttgcaaaagg agataaacaa tttagatcag ggaattatag
    17221 aaaaggaaag taaagaggaa gataaaatag acagcagaaa aacacttgga aaagaatata
    17281 atctttcagg ggcatctatt gcaaggtacc taagattaaa tgaattatct aagtcttgga
    17341 aaaaagatgt ggatgaagat aaaataggtt tgacgatggc agtagattta tcctatcttt
    17401 ccaaagaaat acaggaatat ctgtatcaga agtgcgaaga attggaacta agtttaaaac
    17461 caagcgatgc caaagcactc catctgatga acagacaaga agatctgaat caagagatgg
    17521 ttataacata cttgctgaac ttgaaaaaaa cgaaggtaaa aaagtatcag aatatcaaac
    17581 tatctcagag tgtctataaa aagttttttc atgatgaaag gaaagaagat gtagaagaaa
    17641 ttatagaaaa agcattggaa atttacttta aggaatatat tggtcagtga aaagacaaaa
    17701 ttataaattt aaggtataat ataaggtatt aaaaagggaa aagacctgtt taacaggata
    17761 agatataaaa gaggcaggtg tcagaatgga cgaaataaaa ttgtatgaaa ataaagagat
    17821 acgctccatt tgggacgaag aaaaagaaga gtggtatttt tcagtagtcg atgtagttgg
    17881 agttttgaca gaacaagaaa acgtaagagg tgctagtacc tattgggctg tactaaaaaa
    17941 gagattaaaa gaagaaggaa atgaactgct tacaatttgt aagcagttga aaatgaaagc
    18001 aacagatgga aaaatgcgtt taactgatgt agcagatatg caaggaatat tccgtattat
    18061 ccagtccatc ccatccccta aagcagaacc ttttaagtta tggcttgctg aggttggaaa
    18121 agaacgaatt gatgaaatta tcgatcctga acttacgatt gacagagcct tagaaactta
    18181 tctaaagaag ggatatacac gtgagtggat aaatcaaaga cttcaagcca ttcaggtaag
    18241 aaaagaactg actgatgctt gggatgacca tgggatacaa aaaggcaaag aatacgcaat
    18301 tcttactgat gaaatcacca aagcatggtc cggaatgaca acaagaggtt ataaaaatct
    18361 gaagggtttg aaaaaggaaa atctaaggga taatatgacc actcttgaaa tagttcttaa
    18421 tatgcttgca gaagccacaa caacaaacgc attaaagcaa agctaaaagg acttag
//
